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<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M402</accession>
    <name>A0AAV4M402_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_24561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019335">
        <property type="protein sequence ID" value="GIX66693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M402"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349194" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX66693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="11489" checksum="24A2EAFE301CEC26" modified="2024-11-27" version="1">MTVSFRFSRFSEHFILLFCCMTSAVPRLRFFCSKNCVLLEYYRRYDEGRRRHRGKLLGMRGMKYEICLSSVWIVREWILLLRSHDERRQKCGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4E4</accession>
    <name>A0AAV4M4E4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_293971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019391">
        <property type="protein sequence ID" value="GIX67321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4E4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10722" checksum="E7B99121F735E759" modified="2024-11-27" version="1">MPNFLCSFLEEWRLKSSLSLMPKIWHSLVFKNVWNLNIGEWNSYKLYPTFYILSPRMGNEIYTELSAKGMHSYHSCPRMPVAEKYLHYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5G4</accession>
    <name>A0AAV4M5G4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_680171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001806">
        <property type="protein sequence ID" value="GIX66641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5G4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10838" checksum="8C1DC9D752755912" modified="2024-11-27" version="1">MSNYIEIRKGNLKANEFCDQSQVVNNLPNFTNELDQNLRRKIAPFGVRCEEEDFSLREKDEKKIFQTCRMKKKIAPASEWDKNTNKLPEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M735</accession>
    <name>A0AAV4M735_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_82571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019331">
        <property type="protein sequence ID" value="GIX66659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M735"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="14306" checksum="0D84FA5D547E78E9" modified="2024-11-27" version="1">MSRRREERLVSLFKATEQWWMHHTRQWFVLALCCCVYLRNPTVRKASHVIYSERGKDDFAVCASMTRNNLIPFDVKKTAFRKRRRLFRMYRLEKKTKASAPDSRRQAIIEAYRISDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAV1</accession>
    <name>A0AAV4MAV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_235397_1</name>
        <name evidence="2" type="ORF">CEXT_250141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002066">
        <property type="protein sequence ID" value="GIX69568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000437">
        <property type="entry name" value="Beat-IIIc, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="242" mass="27667" checksum="E758A7D1C71E9D10" modified="2024-11-27" version="1">MTFSLEIKETNLPKHRLLNDSWIFAWISKSVTSLRLLSLDVPDRVARGQGTRLTCGYDLEGDTLYSIKWYRDDVEFFRYVPTDRPPGQFFSSARHQSGFDKSRNGSVFIRDISHLTAGVYKCEISADAPSFQTVSAEKPMSVQGMYFRFSVKIGWPCSTESRSKQCQHLALKHAADITISSVMVQFLCLREFFSKQLLCALSILSLNREASKFDNGKLFLEEESFLNIKFKDKVKELKQLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDL6</accession>
    <name>A0AAV4MDL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-dependent protein kinase catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prkdc_1</name>
        <name evidence="1" type="ORF">CEXT_545221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002007">
        <property type="protein sequence ID" value="GIX68909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14202" checksum="2AC3DC9950B55F76" modified="2024-11-27" version="1">MSDIIELVRKHLETLKTFLDNKKFSDNEGTVSDIIKSIRDNYSNYSLKTQDREILNAHLLNNENGILGFLRSILLLKERMIPSMDMMRIYRHAWKFFDSTTVADIFMLFRCLKSSVTKCFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHH5</accession>
    <name>A0AAV4MHH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_541951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002257">
        <property type="protein sequence ID" value="GIX71833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11064" checksum="8ABA7A27F0F5ECA9" modified="2024-11-27" version="1">MPQIPILKISRKTRIGDPETQKRSFETNIYFFAKHLYEPVDGFNSPWRHKGKDEKRGTEKGVAEKGNAGIEQTIDIRVLKESASRDLMLKKSMTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJ65</accession>
    <name>A0AAV4MJ65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAP30-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SAP30BP</name>
        <name evidence="2" type="ORF">CEXT_55141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019856">
        <property type="protein sequence ID" value="GIX72532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJ65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012479">
        <property type="entry name" value="SAP30BP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464:SF0">
        <property type="entry name" value="SAP30-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07818">
        <property type="entry name" value="HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="299" mass="33467" checksum="BF57C89E2FF21C74" modified="2024-11-27" version="1">MSSESRSLALASLHETYTDSEGEAESDSEETTNEKIISPNKEENSPNSMDDSSKSFKYSKLVSYSTEAHEDEDMSDSADTKSSFDPLDDQSSSENKVAPVGVPPLSPISFHRSLLNLKREEIQLPPESVGRCSKALQDKIGDLYNKKKKGQDMNASLQRRKDFRNPSIYEKLIQFCNIDEQGTNYPPENYDPHCWGPESFYEELAKRQKEEMDKKEKEKKETNGKRFKVEFMSGTVKKSSDSNSEIGKRKSKWDIGISQLPASTLKPAMLVTPSVLPVATGTKPTVISAFGSIVKKSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ML43</accession>
    <name>A0AAV4ML43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Scm-like with four MBT domains protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sfmbt2</name>
        <name evidence="3" type="ORF">CEXT_529411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019859">
        <property type="protein sequence ID" value="GIX72585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ML43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20093">
        <property type="entry name" value="MBT_SFMBT_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004092">
        <property type="entry name" value="Mbt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050548">
        <property type="entry name" value="PcG_chromatin_remod_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247:SF129">
        <property type="entry name" value="SOP-2-RELATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02820">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00561">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51079">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="MBT" evidence="2">
        <location>
            <begin position="13"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX72585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11964" checksum="4B87D5CE188F91AF" modified="2024-11-27" version="1" fragment="single">MESTIKDGTDPDFVWQDYLEDTNSVSAPPTAFSSGFKVGMKLEVPNPEDSAMYWPASVIMTCGDLLTLRYLGYGDDRSADFWFNIKTGEFHPIGWCAFNSKKLKPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMB0</accession>
    <name>A0AAV4MMB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_372711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019974">
        <property type="protein sequence ID" value="GIX73672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14593" checksum="656A68096A97549E" modified="2024-11-27" version="1">MTDSQSIKGAETHPNSSDYNGQKAKKIRLSSLLTQDSHYASLWKYALRKWNMIAKSASVNTIAFQIVCRKDSIDGCSSSRRPMTGIRSKMRPVNVSEHFTKCPSIFSAHVYVEITCQNGLIFVTLIPYCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPY9</accession>
    <name>A0AAV4MPY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Fat-like cadherin-related tumor suppressor homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">kug</name>
        <name evidence="12" type="ORF">CEXT_343391</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020001">
        <property type="protein sequence ID" value="GIX73895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030855">
        <property type="term" value="P:epithelial cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001736">
        <property type="term" value="P:establishment of planar polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007424">
        <property type="term" value="P:open tracheal system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000013">
        <property type="entry name" value="Cadherin EGF LAG seven-pass G-type receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000015">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026">
        <property type="entry name" value="FAT ATYPICAL CADHERIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026:SF125">
        <property type="entry name" value="FAT-LIKE CADHERIN-RELATED TUMOR SUPPRESSOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="51"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="155"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="260"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="366"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX73895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="544" mass="59912" checksum="14E108892CBE29E3" modified="2024-11-27" version="1" fragment="single">IIKTVKNLDREKQSRYNLKAHVEDRNHPEWECTSLIEIYLEDVNDNVPQFTQPIFIVAVAEDVPVGSLISKVHAVDKDLGGSRKISYSFLNNHLGQFEIDPKTGIVRLRRSLDRETESEYNLTVQATDHGVPSLSSTVLLSITVLDVNDNPPEFTNKIVYATVSESVPIGSEITSVHATSEDIGVNAEITYSIIGGDEQGVFEISATGGQIKLLKSLDYEAVQDFFLTVQAVDGGSPPLSNQAVVNITVTDSNDNDPIFSQSSYRAIVREDATVGSQVIQVLANDADSPPNAQLTFSIMSGDDDNHFKMDSNSGVIKVSKTLDREMVPNYVLQVMWSDNGIPQLSSTAFVNIEISDVNDNAPMFSQNNYTVIIIQEGRPLGYTALKFTIIDADVPPNTGPFNLEIVSGNEDAAFRLVQQDASLRTAIKFSHKRKDRYESHLKVSDNGSPPLFSDALVTALIIEECRFPPVVSSLEVVINSYRDEFPEGVMGRIHATDGDPYDKLYYEVVSPYKDMFSVDREDGTLVVLPGLDVGSYNVNISVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRT0</accession>
    <name>A0AAV4MRT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_150031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002475">
        <property type="protein sequence ID" value="GIX74141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7595" checksum="2C3D8737D8A7E9E4" modified="2024-11-27" version="1">MEGSQSYTRTATVTVCTVLGCLLMASDIVGGFNIDTKSAVVHRGTPGSWFRFFGGTLQRQGKQLLIRKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MST3</accession>
    <name>A0AAV4MST3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_754201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002589">
        <property type="protein sequence ID" value="GIX75459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MST3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043842518" evidence="1">
        <location>
            <begin position="17"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17912" checksum="FFFE99B16F21456A" modified="2024-11-27" version="1">MFDYRILLAALKAVWAQKVLCLWCTTEAFCIGASDRNSCFNPSQLKQFTSDSKRRTLNNVLTELFNRCGQDCFRLCVRYRSFVQNFLDLAPPFCIGSSDINSYFNPPRLKQFTSDSKRRALNNVLTEFVRRVREVLGENFLDLAPVFFNPRQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTJ1</accession>
    <name>A0AAV4MTJ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sodium channel protein Nach</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_50420_1</name>
        <name evidence="2" type="ORF">CEXT_532361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020192">
        <property type="protein sequence ID" value="GIX75729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="49840" checksum="07431B4EA93DD966" modified="2024-11-27" version="1">MSASKSCTWNAKFGHPSDVDWNQETVHTPQRTKPCSCSWNCGNPKKRRQLVEILSDVQRSRHALHLLQKNTSRLLKFIYKILFSLCILAVISNVALLLQEAFDQESTFINTINKDVELGREEDPGYFPDYPQITLCRKPFLQSSYRNLVEYSYLALGYPFIPFTPEEVSMIVEISMKLDHEKLKSEVLKFHNHLEDMEKDFNNCKTPLRLFRTDARSSSCTASPWCSPSTAATSSDQVLTSMGLCYALIDSKEILRLLENAPVDFSIIIDLFSPPHLEVNGRRIQRVPQRPQRDVAALPAVGRSKDRAGTCHHGQCPAGQNGRSALHTPWHSLTVNCPKWPFSSDPLNLKPHRYSYRTCDTYTYFISLRKACNCESVFFPGIPTLRYCRPKDIYICFTAATIANNFTDLVNICRQPCIVYRYKSEASYIGLGGENLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N1F1</accession>
    <name>A0AAV4N1F1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_687691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020301">
        <property type="protein sequence ID" value="GIX77144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N1F1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="214" mass="25033" checksum="16A753FEA0EB749E" modified="2024-11-27" version="1">MWIKATSSHYKSSTSIASKLFIFENQIYINILQSGYTNCIKAILYTTSKYDGINYKTTEPTAPKIFRMAQIWGSKLDPLIAKLSYTNSIKNSLHKRIKPTPTSYKGTILTTSKLFHIRQVKKYDDTSEIRRNLIRSLLTLKVCSHRERERRDEQAIFAKSNLLAEMKSKLSPPLSPYTQIPERVMKRPFSYARNESLWWGDQPVKRFARTKWEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4Z3</accession>
    <name>A0AAV4N4Z3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_686731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002971">
        <property type="protein sequence ID" value="GIX79779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4Z3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="50" mass="5542" checksum="0429F2974FB0380A" modified="2024-11-27" version="1" fragment="single">MSEIFTFGIRTGERAGATLRYGVDHSRGSTATFSTASREFEALARRPFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6J7</accession>
    <name>A0AAV4N6J7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_743781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020595">
        <property type="protein sequence ID" value="GIX80467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6J7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="46" mass="5451" checksum="9AA2BD14AF5E3B6D" modified="2024-11-27" version="1" fragment="single">MLKSDEFEEIEIIPDIHIQDDGYTCLENDFNIENEYLGIKLKNFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7S0</accession>
    <name>A0AAV4N7S0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial inner membrane protease subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_86651</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterodimer of 2 subunits, IMMPL1 and IMMPL2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S26 family. IMP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002992">
        <property type="protein sequence ID" value="GIX80013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7S0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037730">
        <property type="entry name" value="IMP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041:SF2">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX80013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17963" checksum="5F8F3F1577A62FFF" modified="2024-11-27" version="1">MTAERQTKPSSVPSVRKKLTNDELMEKDDAWLASSFTTASRLASSFSTASWSPRDPDEKLIKRVIAVEGDTVKASDMLRYVSIPAGHCWVEGDHTAHSMDSNYFRTGVRGVDLRQGVPHRVAPVPLAEAEQRHGEETRRLATPLTPPHHSMTNSKCYVDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAX0</accession>
    <name>A0AAV4NAX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mortality factor 4-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MORF4L1</name>
        <name evidence="7" type="ORF">CEXT_433551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020614">
        <property type="protein sequence ID" value="GIX80682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18983">
        <property type="entry name" value="CBD_MSL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000024">
        <property type="entry name" value="Mortality factor 4-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.30">
        <property type="entry name" value="MRG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008676">
        <property type="entry name" value="MRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038217">
        <property type="entry name" value="MRG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026541">
        <property type="entry name" value="MRG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053820">
        <property type="entry name" value="MSL3_chromo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880:SF48">
        <property type="entry name" value="MORTALITY FACTOR 4 LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880">
        <property type="entry name" value="MORTALITY FACTOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05712">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22732">
        <property type="entry name" value="MSL3_chromo-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038133">
        <property type="entry name" value="HAT_Nua4_EAF3/MRG15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51640">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="6">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX80682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="318" mass="36226" checksum="79EE678ABF44364E" modified="2024-11-27" version="1">MAPTPKFVIGEKVLCFHGPLLYEAKCLQSKIKERYVEYFVHYNGWNKNWDEWVPEIRVLKFNETNVQKQKELAEAQKAKKKQLAKKLGTLAVAKKEVDKATSEPSTSSGKTSALRAEKRPGCAAALSSDQVQKSKKGLKVIKNENLNLTSVKVTMPDAVKEWLLDDRDLIIHQEIVQLPAQITVDQIFASYVKEKVSTKTFTKAQSVVFFSENMRALFNVSLGKSLLYKFERPQYGQLLKDHKGKKMCELYGTIHLVRLLCHIGEMLVSAGLGNQDKAHIKKFVEPVEDMLRFMASNEYFSEDDYVVASPEYIRKTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJF2</accession>
    <name>A0AAV4NJF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_107051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021015">
        <property type="protein sequence ID" value="GIX84932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14139" checksum="7D66F3DEF74A2B01" modified="2024-11-27" version="1">MSKTSLTVTKLLLFYIIHISTIYDLCYLDLNFSSSYADNFIITSALHHPFFSIVTHLQAHHLPQYFKVLNPTSTQCLIATPLFTSRNFNKGTFQELSVIKNKLFPRTIPHHNCSVLFTLYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKJ3</accession>
    <name>A0AAV4NKJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_337231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020904">
        <property type="protein sequence ID" value="GIX83802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10234" checksum="90AEA5C17B12475E" modified="2024-11-27" version="1">MNLNIELTALIKDHDRSRRGRFKSAVETAGEDERSLMNDGGIPSYRHFSPQSIKIPICVLLKINGLRSWREWGKGESSRILTREANYDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVM6</accession>
    <name>A0AAV4NVM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_425951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021317">
        <property type="protein sequence ID" value="GIX88403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13727" checksum="178819A42794E7E0" modified="2024-11-27" version="1">MSAKKKKKNRSRSSATDPIRCPECAVVRALSDGDNFTQSVSSEKWLGVVKSETDWWILVVLPRLISGQRDINTRKCIIRYRIESWNFLFIRSERMWICNPQTSFRDANVCINMELEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWG4</accession>
    <name>A0AAV4NWG4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Macrophage mannose receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MRC1_3</name>
        <name evidence="3" type="ORF">CEXT_328601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003829">
        <property type="protein sequence ID" value="GIX89154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043977469" evidence="1">
        <location>
            <begin position="26"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="40"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="188"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="297"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="412"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX89154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="555" mass="63448" checksum="D817D687D3AECA1E" modified="2024-11-27" version="1">MWIDMAFSVHLLLLVTLSFIPFLNGYKQFEYCTGTSWIKFQGNCYLFRSSYGNRVSYYDAEDYCRTQGAHLVSIHSEAENEFLLDTMVEGRFGGRLWIGLNILAGKNSQQWSDESPVDYMKKVAKEFYVNEKCFIMFGSKKGWRPEDCSLHYAPICKRPESVTPTPIPPVTTPPPPTGNCPKDWIQFAFLTQHLYPLNTSAWIGMHHIDSDEIGHDLVFGWMDNSRTDFTYWAKGHPPPGTWKYCGCLSYEGIAKGQWIADYCEINKKGYICQRPTVSDLPIVPPKPSKCGDGFSGYRNSCYKYISTPENQKKAEETCQNLGGHLVSLVDSLEQSFLLNFIEQKSSLVWNGLKTVEGTRYLRWTDKQPFYYSNWESEPKLPFVCEVTDDAIPDFPETLGTCPSSESSWVDIGDEYCYHVAESPNHILSWDTTSRYCLTKGMKMIKANSDHQLKSLIAYLWRESYNVHLSLIRTFDKKSFIWTDGSSLDYTNWDTREPSSFSQGNDCVAFDQSTGKWKTINCSNGGVVMCQIPKIKKRYWASGHLSGVLPVIHSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P243</accession>
    <name>A0AAV4P243_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_688931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004007">
        <property type="protein sequence ID" value="GIX91277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P243"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9328" checksum="60DEF153CB7BB055" modified="2024-11-27" version="1">MALSSAVMAIVGIPLVKTYSFVNFHAFLPKQKGVKTLTLVGAKVFGGKCLLVGCAFLGWLRLSSSENSKARGGKILRREEQGKVFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3E5</accession>
    <name>A0AAV4P3E5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_749071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004049">
        <property type="protein sequence ID" value="GIX91690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11771" checksum="FD1E8EDA54150F94" modified="2024-11-27" version="1">MPTAQKTSSTARNTQLRKCTRNVLMRFAQEIASAYLPAALRDASTLIMTALSHTTLMTSILMTCTQHNVLSPMRDFNLNDVYLTEKLIESIAQQVPFPEYLFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6H2</accession>
    <name>A0AAV4P6H2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_309961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021657">
        <property type="protein sequence ID" value="GIX92093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6H2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10276" checksum="8FAE35942A468A49" modified="2024-11-27" version="1">MAMTMMQVRAGKSRFLLSAALTPFRCIDRPRKMKLNTPPGIAEVAIRWPREWFILTRGVKMPPSKRKKITEKKHLSLATLLCVFRNGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6V5</accession>
    <name>A0AAV4P6V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_387201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004114">
        <property type="protein sequence ID" value="GIX92325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10163" checksum="A89B7D2864A59A19" modified="2024-11-27" version="1">MQQQRPLAEPFESGGARAEQFLDDGLLCQGARVAQVLVVTGDLPQDPAQDLPGPGLGQAAGHVDEVGGGEGAYLGTHCGGEEIVSRQKHFIHVITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PB88</accession>
    <name>A0AAV4PB88_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Delta-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">CEXT_391971</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="16">Putative Notch ligand involved in the mediation of Notch signaling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Membrane</location>
            <topology evidence="1 16">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004357">
        <property type="protein sequence ID" value="GIX94303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PB88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045179">
        <property type="term" value="C:apical cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043208">
        <property type="term" value="F:glycosphingolipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048018">
        <property type="term" value="F:receptor ligand activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030855">
        <property type="term" value="P:epithelial cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030718">
        <property type="term" value="P:germ-line stem cell population maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042063">
        <property type="term" value="P:gliogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046331">
        <property type="term" value="P:lateral inhibition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016330">
        <property type="term" value="P:second mitotic wave involved in compound eye morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035239">
        <property type="term" value="P:tube morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000018">
        <property type="entry name" value="Delta-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000061">
        <property type="entry name" value="Delta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000117">
        <property type="entry name" value="Delta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000431">
        <property type="entry name" value="Delta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.140:FF:000001">
        <property type="entry name" value="Delta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000143">
        <property type="entry name" value="Protein crumbs 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000122">
        <property type="entry name" value="Protein crumbs homolog 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001774">
        <property type="entry name" value="DSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051022">
        <property type="entry name" value="Notch_Cell-Fate_Det"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049">
        <property type="entry name" value="CRUMBS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01414">
        <property type="entry name" value="DSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21700">
        <property type="entry name" value="EGF_DL_JAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12661">
        <property type="entry name" value="hEGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00010">
        <property type="entry name" value="EGFBLOOD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00051">
        <property type="entry name" value="DSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51051">
        <property type="entry name" value="DSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="2 16" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-0221">Differentiation</keyword>
    <keyword evidence="12 14 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 14 16" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <keyword evidence="4 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="826"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="DSL" evidence="19">
        <location>
            <begin position="138"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="281"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="319"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="385"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="424"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="478"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="517"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="555"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="18">
        <location>
            <begin position="593"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU280815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="GIX94303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="961" mass="107172" checksum="8C27EF257FAE20A8" modified="2024-11-27" version="1">MYPGIVTSAVTTDEVSLPYAIVQSSIVVMPSLADPCTNNYPHPPLCLTADSITTNLRVLKQELMMIIIGMVWRLPLFQNLARSFTFILDALDVVNKDIPYTARIIERKVYSGIILPSTEWHTLLYTGTAAKINFRIRVICGPYYYNSTCTVFCKPRNDKFGHYMCSDKGEKICLPGWTGNTCEEAICKEGCHPEHGYCEQPGQCLCRHGWKSELCDQCVPYPGCKHGYCNGSPWQCICDINWGGIMCDQDLNYCGNHHPCQNSGTCENVAPDQYRCVCSQVDNPCMINPCLNGGTCSELNSTSSCECTPGWTGAHCEININECESSPCSNGGTCVDLVKWLSLHLHTRMEGIFRKNCSHQLSDCILPYCEDIDSCIAYIGSNTSNAEIVKTNVCGEHGKCISEPFSDFNCVCDLGYTGRYCHENINDCASYPCRNGGTCIDGMNSYICLCREGWKVHNAMLKLDFGVTASRDGKENLQFDHCDVTTCQNGGTCRDMGDTFHCTCNEEWVGHSCHIPINPSCQSNPCQNGGTCINKENTYLCMCREGFGGQQCQHNIDDCQPNPCFNGGHCIDGINWFMCECTPGFTGPDCRININECASSPCSAGSTCVDGINDFKCICPPQKTGRVCETDIKKKTCEFQGIIRMDGSQWEFECNTCLCQDGKVICSRDSFVYLFILHHVFSKPCAVTGRCLSEPNANLYIADHLPKHCKPNNAIISDNCAKLSVKFSENILPMQILSNSYCKFINNNRICLVIQKYIWSLDFVNIPVFAQCAIQENTVQLMEITISTDIKETKETQLVLMKVVQEVMTETYAIASESIAVNQQKYLVPFVTSLSIALVVGIAALIIIFKQRCHQMKISCSFSHSDENNKQEHPSSVNNQNADNWKRYLNKLHAPSDTATLSDCITKVDSSFYQVSDKMYKTLPPEANKNRSIPLPFKNNLHKCDSVMQGKECYPENELIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUP3</accession>
    <name>A0AAV4PUP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_42161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005074">
        <property type="protein sequence ID" value="GIX99650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="45" mass="4822" checksum="5DC59723698BEF0F" modified="2024-11-27" version="1" fragment="single">ALLCQEAVSLHAVEPIPPFRDWLAAVVTTLSLLNGRSDCGNEEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW47</accession>
    <name>A0AAV4PW47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ankyrin repeat domain-containing protein 54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ANKRD54</name>
        <name evidence="13" type="ORF">CEXT_197851</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005043">
        <property type="protein sequence ID" value="GIX99402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="11" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX99402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18349" checksum="C5833DFBE6540573" modified="2024-11-27" version="1">MMLILVHLIIDKRSALHFAAAGGHTEIARLLIERGADLINGLVGNTPLHLAACTTHIEMVTLLLKAGTDINALDYSGRSPFQLAQSKLKLLQRNTEYSSAQLKTEVEHVLEMMQVYLQRSGRSVEMDLINSFSNRLHHHQTREEVDTDVKDLLSSLSHLNIQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWB9</accession>
    <name>A0AAV4PWB9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_603481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005157">
        <property type="protein sequence ID" value="GIY00236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWB9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11190" checksum="3A050EC7CDD470B1" modified="2024-11-27" version="1">MRVKACVLKRTRLAFAVDEFRKSLSVSYKGLMLREVTGMSRQGKGPTPPNPAVPGAVAQQAQQYLNKTLWPDATQTTRPVAEGKKVESWKESVMNSLSVAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWW0</accession>
    <name>A0AAV4PWW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_781961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005341">
        <property type="protein sequence ID" value="GIY01582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="21710" checksum="9F3F1263B4E3D188" modified="2024-11-27" version="1">MNVAVTVSCKSTLQHDEAQSPKPNNYRSASESMSYSTSNNKHTASNIMTGTRIHLGPSAFLPSTQEKLRFWNSGIDPGHYHSSLAIQRNKTKKPSVSPERTKAKQPLIHSFSPLRCLCWGKIIKRDICSMPRVTNCPSDQNHPDYVIAGLPDNGGTKELDKADIFLAFPPLFVSACCPIRAHKRLRLFSYLLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZI6</accession>
    <name>A0AAV4PZI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_647901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005334">
        <property type="protein sequence ID" value="GIY01542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15717" checksum="3C25957A77EDD1B0" modified="2024-11-27" version="1">MYKETAFAEKEKDSIQRDKFSSPVNHLESDMEQSAELAAGRVGLEPFLFQVQRIFQDLKTGAFEVLKFIRSLRGGKGPKETFSTAPIIRESFFHVTGQGASSSWFSETPDAKRTFGIKELVQGELLIKEESKDFRCTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1Q5</accession>
    <name>A0AAV4Q1Q5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfotransferase 1C2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Sult1c2a</name>
        <name evidence="4" type="ORF">CEXT_277961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005409">
        <property type="protein sequence ID" value="GIY02102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1Q5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="51"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="296"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY02102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="340" mass="39188" checksum="29F108F071A40F7A" modified="2024-11-27" version="1">MAGTPQEKQIPSITMAETDSPTCSQFVDGFQIFGKLPVENFRAALEYKPRPDDVFVATYPKCGTTWCQHILTLILNHGELPSITDFFRTSPYLEFVGVKGVEKMVRPGSIKIHLPFHLAPFSEEAKYIYVTRNPKDCCVSYYHHMKDVHQGFGFQGTFDEFFELFLEGKVDYGDYFDHLLGWYEHRNDPNVLFLTYEEMKADTEAVVLKMASFVDEEKYAKPLREDPEKLSNVIKLSSVKHMREGFMKNFAGLLSQPMDELLNNPDIPEEFKNLFSSVAEMMKPTEGAENQPPPVMNFIRKGVVGDWKNYFSEDQRRRLDEKFAERTKGTDIANLFKNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4E7</accession>
    <name>A0AAV4Q4E7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein phosphatase 1H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ppm1h</name>
        <name evidence="7" type="ORF">CEXT_121171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005559">
        <property type="protein sequence ID" value="GIY03252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4E7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF354">
        <property type="entry name" value="GM14138P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="164"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY03252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="533" mass="59782" checksum="FD4C353E02729849" modified="2024-11-27" version="1">MFNRVKNALYNVVGGLDSYPAIKDGEYSDRPPLKFRYTRPTFLQLTSDDEVQVSADHVIRPIIVPRDITKLPWNSGYAEAINAGKSVRNEDQGATMRGVLYTLAAISTKPEIQEPVQIKISPPDPIVPKQNEAKPTTETELNNVADGDDSTNLNNTNVSDDSKFTTPPSTPEPLRKTVLDHTIPWIYFALFDGHAGSGVADKLQEVADLLILPPPQLNLLAKGSHERSAQPAGFLGFSSERDVTADSLITGALESAFWEMDRLIAIDKRHYTMTGGCTALIAVFMFGKLYVANAGDSRAVICRGTKTFPMSNDFTPETERNRIRKLGHLRPELLGGEFTHLEFARRPARKDLGEKILYRDAYMSGWSYKTIAMEDLKFPLIYGEGKRVILATIGVTRGFGDHDLKALNTDIDIKPFLSPEPEVKIFNLLEEELTDGDVLVMGTDGLWDVTTNEKSAEIVQKSLDHFPANDAQRYKYRYTSAAQDLVMHARGKLRERNWRTADNKLATIDDISVFVIPLRPYKEEYLQWEKSMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q583</accession>
    <name>A0AAV4Q583_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nrf-6_12</name>
        <name evidence="3" type="ORF">CEXT_784051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005567">
        <property type="protein sequence ID" value="GIY03347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q583"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF0">
        <property type="entry name" value="O-ACYLTRANSFERASE LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="514"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="557"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="192"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY03347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="615" mass="70288" checksum="F6830A65C35F7ADF" modified="2024-11-27" version="1">MIQVELKTFVGRYCMVGYHSPLMAPLTQKTPTGENYIDAYGNPPDWFKLLIIINFLSIFRCRLISKSGPYLTRSAFWFGTCVPSTCSEADVKEITTYATKPMGFNVKLAGCEVDEPTEWPTSALIAVCCLSFILGFCILGTIVDIIIRYFIENHQYSEPDQILLQILRAFSLYSNTEKLFASASGSNTLGCFHGIRFFSAVWIILGHTYFFTDTWKFLKYRDALKIDDLFNYYLPVAVLENFSIPVGSFFFMSGFLLVYSTWKKLEKSDGKLNLFMFIVHKYWRMTPALGLMIAMFLALPVIGSGPLWGSTLNPPIEACENHWWTNLLYINNWWGSEDYCLIHTWYLAALMQFHIIGIFILLLSFRWPTIGVLLGFTTAIISCVMTALLTIWNNFPMPTPGINKDMDVMEDYNTKIYIKPFCHAPTYLIGMVVAHLVLKYKDKQIGLGYQILGWLLAIFGALASVYGIYAPSERVEVRAFYLSCYRIGWTMSIGWLAFACITGRGGIANRLLSWNAFIPLGQLSYLVYLLHPMIMLYRTASLRERINYGHNELVFEFLTYTVIAFSLSYIGYVAVEKPFLILEGIFFRNKLQVNLKKTIVKKEPVITYAAKTIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBZ0</accession>
    <name>A0AAV4QBZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_797061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005963">
        <property type="protein sequence ID" value="GIY06481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="15931" checksum="862F56FC45C34A9C" modified="2024-11-27" version="1">MNPIESPQNGPSSASHGYEGRGGGVQCIANLLMLRAGPLIRNSSSRRCSNDLFWKWFFLSNSLKPKEPISRIHHDSTQSLFDASEWNFSPSATDSRRVSESFSATLFRGIQLHSPTYLYDSLHLHTVGYLTLNLTFARKCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHY8</accession>
    <name>A0AAV4QHY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_757051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006144">
        <property type="protein sequence ID" value="GIY07721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17037" checksum="218EDA3562640D73" modified="2024-11-27" version="1">MSCIINWSSSSITNGHTSSIGHHLQQQMAIINWSYLQLVIIFIFNNKWPCIINWSSSSTTNCHASTTNGTQKWHCLEKSEIKIAAQTNNASSTGILHYQQHASSTINGHASSTTNGHASSTKNGHGSSTTNRNQKWHCLQNMGDNAGLPNGTFPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QI07</accession>
    <name>A0AAV4QI07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_349311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006268">
        <property type="protein sequence ID" value="GIY08566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QI07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.300.10">
        <property type="entry name" value="Tie2 ligand-binding domain superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042635">
        <property type="entry name" value="MEGF10/SREC1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043:SF8">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="239" mass="26841" checksum="501F7DDA0542A680" modified="2024-11-27" version="1">MRVWVLWSGLPKQRCHCAYGDMHCNSVTGFCVKLGALEAEGYSCEIEGKPSYKCYYVNLEIHTQVQMSLNMCSGSCIEARDKCIEQTATVSHCPLGTYGTKCKNVCHCAENDYCDFISGRCYLGCENGWEGPTCGTCRRGRYGDNCERICHCRDGHDDCDEHGFCMSGCEPGWSGFTCQIKCIPGRFGPNCAETCRCPGYLFSVCDRVTGECRRQNEPNVHHIDRPHVIEKVSRILFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJX4</accession>
    <name>A0AAV4QJX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_585241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006345">
        <property type="protein sequence ID" value="GIY09241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="365" mass="41793" checksum="240E3AD7A7F857E1" modified="2024-11-27" version="1">MQAALIETITLKRKLLEKLAERKPETVLIWLRVGQTADRIHQSLRGENAKKIRTVSPPNKLMTRFSSGWRSQMGGCHRSETEQTQFFCFGIFLISMVQFQETVREVSRAETSKTVLIWLRVGQTAYRIHQSLRGENAKKMRTVSPPNKSITRFSSGRHFSTGWVSPIRNEEHKFSVSGFFSFRCFSSSEFEICYQKFVEKDKWSGSRNGSHLAAGGDKLRIAFINLRGAKMKKMRTLSPPPNKLVTRFSSGRRFSTGWVSSIRNGERKFSVSNFSNGSMPHLIRNVNFEKHSFKPSQSFPRCASGAKRTITLKRKTAREVRGAETRNGSHLATGGTNSVRLSHLSISEWRKCEESENRFPFLTRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QK29</accession>
    <name>A0AAV4QK29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_117101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006343">
        <property type="protein sequence ID" value="GIY09209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QK29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="15000" checksum="16015C6161D31E7E" modified="2024-11-27" version="1">MEPFNDKRQEQKSLEAFLARSNNAQPGDFEFASRMFCRFIFTPNHVLQFGFGLQLKKERRPVQDEYILNWNPSHWIQISLFAEHHPINPPWTIKTSNVRYYYLVEIHFKRYFPVQSSVTLYAVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R428</accession>
    <name>A0AAV4R428_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_15021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007385">
        <property type="protein sequence ID" value="GIY16485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R428"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10477" checksum="57CECE65FC7D8657" modified="2024-11-27" version="1">MTKRMSPNSLYKLCLEETSFHLIENFIHWNREDTNPFSQANCNIVNDLFQFLVIHMNIETPSPLKLLLKSGQLQDFMLDGLVFTENSGGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4G8</accession>
    <name>A0AAV4R4G8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007177">
        <property type="protein sequence ID" value="GIY14988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4G8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="20233" checksum="B4B84D86130978DC" modified="2024-11-27" version="1">MQFHLTHIKIYKRKEKKERKPLCLQTQNRPNWCFRKTSNKNSERSRRSGPPLLPAGRCSLPGKKKAPLFFFFLISFLLRSRAKNKELQDGWEDSNEDLEGGGGRKGVSGTRARRSPFAKERKRERESENLLKATLIRAWVARLLWCRWVAMGTDLRRGPPPYCVLLLVFKSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7I4</accession>
    <name>A0AAV4R7I4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_128741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007561">
        <property type="protein sequence ID" value="GIY17908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7I4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10244" checksum="159592C1347109A3" modified="2024-11-27" version="1">MMKMKTQSPSERLVKEQRKISANIAFLTRSNAESELKRNSMQAAHSFTFSTSERSSTAPETDWWMPATIITKPARGPRELTNQGQDVNGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGT5</accession>
    <name>A0AAV4RGT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nephrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_100811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007769">
        <property type="protein sequence ID" value="GIY19541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY19541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13792" checksum="BEC4CD9659D19588" modified="2024-11-27" version="1">MVAIAFAHHFNSGVCFFPVRPLEVSIEGNRRPLSANNPVELVCRATGSRPPAAITWWKGNTKMKRTKERISIDGYVTTSILIFTPTSEDSGKYLSCRAENPLIQGSAIEDGWKLDINCKLDTCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGV9</accession>
    <name>A0AAV4RGV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Homeobox protein Hox-A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hoxa1</name>
        <name evidence="10" type="ORF">CEXT_634171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007840">
        <property type="protein sequence ID" value="GIY20131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000113">
        <property type="entry name" value="homeobox protein Hox-B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046327">
        <property type="entry name" value="HXA1/B1/D1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45946">
        <property type="entry name" value="HOMEOBOX PROTEIN ROUGH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45946:SF4">
        <property type="entry name" value="HOMEOBOX PROTEIN ROUGH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="9">
        <location>
            <begin position="72"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="6">
        <location>
            <begin position="74"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="125"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="137"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY20131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="20862" checksum="56F56EE5B8013088" modified="2024-11-27" version="1">MIPKLFRREILHLSFGSRPRFYSDYPITLPACLFLITGRRQKSGMPVKSDYNGYNSSTANGNDPNGGPGTGRTNFTTKQLTELEKEFHYNKYLTRARRIEIAQALHLNETQVKIWFQNRRMKQKKRMKEGLIPTDPPSSGGETGSSPPVCPVGSVTGSASGSSPNSVPSTSVVVSGQLTPPDTKSVTLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RI65</accession>
    <name>A0AAV4RI65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_577431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007915">
        <property type="protein sequence ID" value="GIY20626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RI65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13296" checksum="FECC562567354C31" modified="2024-11-27" version="1">MRVPLVPEGCLPVIPPCMICIRRSLHHTKEDHAVDNVVGTRICTKITERPFVSPFCIVWAVCFPYLPNEQRGLLSPGQLNPCSEIWAAASNLDKHSSPTPMGPNDAIILPSLCASLSWSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLP8</accession>
    <name>A0AAV4RLP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_84791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008057">
        <property type="protein sequence ID" value="GIY21811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10877" checksum="C1681E1C2014A09E" modified="2024-11-27" version="1">MKWNLLTVTEFPMSFQKLRIIQDSVPGTSLDHFTPIFQGHEESRGKNCSSILNSQLLTPFRWNTLICGFQGLSRGVSFSYEHLISILFLWPEGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RR37</accession>
    <name>A0AAV4RR37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_264431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008336">
        <property type="protein sequence ID" value="GIY24004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RR37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10606" checksum="F296F44229B7A4F9" modified="2024-11-27" version="1">MKFERIWTNGSSVNLMEFYCTGVFGELRDRLKSSKFCGWRSFYGVFLSRCSEQHVEEPVGGIKVLFSAESASFALASFDESACLSFSCDSSCFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY04</accession>
    <name>A0AAV4RY04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_142861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008440">
        <property type="protein sequence ID" value="GIY24693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16472" checksum="E406D079187B4622" modified="2024-11-27" version="1">MAHERVYVEEKSRLLFFWRSCALGVAFDIINTPDLVHKLRFPLQPMCCFFCAPARLPPLAFCPPGLFYTACLYIRWFCAPILCFLIPSILLQPLFAIPPCPPYSSWVRFLEALFAVGRKSRTDKPPLSHQGIQTKTAGSIQFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY49</accession>
    <name>A0AAV4RY49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_621741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008736">
        <property type="protein sequence ID" value="GIY26818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9716" checksum="FCE9EAA539573985" modified="2024-11-27" version="1">MASKQTDHARDAITMPFFTPLIFNNDDCTERVITVFKSEGISTMSLCHSPKDAVLETAKRRIWLETIFRRSCDAERRSVLLLPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1B5</accession>
    <name>A0AAV4S1B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_275731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008851">
        <property type="protein sequence ID" value="GIY27769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10487" checksum="415FDB9766584CCC" modified="2024-11-27" version="1">MKLSKQLLLAEIMDPLSIAACFSPILDVKNSASDLFSYVGDPVYLLTVEVLHSKNNYIFFDPSSWDSNFCAPYIFVNFGTDNIRVKAGVNWFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8Y1</accession>
    <name>A0AAV4S8Y1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_554681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009252">
        <property type="protein sequence ID" value="GIY30615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8Y1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10919" checksum="3EF0E31B5E6AF386" modified="2024-11-27" version="1">MVVINSAHCPMKRLIGPVNEMKHDPSNLATHRPGLHPFIEPLPHLEGLRCQLLTNRTLNHAARDTVNGLLFFFFFSRRKSVASWKKLAFVGINKCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAZ9</accession>
    <name>A0AAV4SAZ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_142557_1</name>
        <name evidence="2" type="ORF">CEXT_692111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009386">
        <property type="protein sequence ID" value="GIY31468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="24567" checksum="BEC7130C286D6F4F" modified="2024-11-27" version="1">MVVWWYGGMVVHGMVVWCMVWWYGAWYGGMVNKMVVICLTCTLLQDLYDNLLDQLNNDHLTEEMEKLLEVYEIMTTTIRNIDECFSFPAFLATLLNLVGLFWTGYRIAFLTNNLDHSFFLICPVVYLLSHHLLLLISASKTNEKAAKAKLITQCLLRNCHLETRRKIKYEKNIALESNLTSWKIYVFDRSLLITSFGCLLTYGILLGTLGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBU5</accession>
    <name>A0AAV4SBU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ZZ-type zinc finger-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ZZZ3</name>
        <name evidence="4" type="ORF">CEXT_621271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009151">
        <property type="protein sequence ID" value="GIY29900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037830">
        <property type="entry name" value="ZZZ3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705">
        <property type="entry name" value="ZINC FINGER, ZZ DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705:SF0">
        <property type="entry name" value="ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="147"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY29900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="223" mass="26160" checksum="2F09C6E7504B068E" modified="2024-11-27" version="1" fragment="single">MDDIQIKIEPVDFDSNLDIMPGTSNTSTEDSETHDSNILQAHEIKKENFETTQEMDSDSLDEFCFDSDHPALKNNQDYKELIKAIAVLEAQRTKTIQDIDFPVIDWSKYAINDNSSRRQQTRLSRRAALDPYRAVFKDKSCQSQEQKTNKPNQYWTVEEQKKLEELLVKFPPEEIESRRWVKIANCLENRTPVQSRVQEIFHQTPESWHAIPGRMPNLQYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SEL4</accession>
    <name>A0AAV4SEL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine proteinase stubble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Sb</name>
        <name evidence="5" type="ORF">CEXT_519771</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009290">
        <property type="protein sequence ID" value="GIY30905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SEL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="141"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY30905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="368" mass="40886" checksum="75E8BDF1B46FE182" modified="2024-11-27" version="1">MSPSTINEQMSSSLENMRTSTSGDASSFNEIFGDSTTNTAEETIITSTASDLNRETVFDKTESTAKTVYTDIPHTETSTDKDIFLTSTSTPEITETVPTHITTETTYTTTEVPRTTTELDLASADYKEVCGKPVPGPMGRIVDGGNSYFGEWPWVLETLTHFSPRQMHQNSVDGVPLADILLRMGEYDITHENEPLPFVERRVQIIASHPQFDRRTFEYDLALLRFYEPVVFQRNILPACVPAGNDTYVGKYATVTGWGRLYEDGPLPDVIQEVSLPILTNKQCETMYRSAGFVEEIPDIFICAGYVNGGKDSCEGDSGGPMVLQEEDGRWVLAGVISWGIGCAMPNQPGVYTRITKFSEWINQIIIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFM4</accession>
    <name>A0AAV4SFM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_811241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009547">
        <property type="protein sequence ID" value="GIY32794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10619" checksum="371D6DB819227721" modified="2024-11-27" version="1">MGNLEEAPGIYSSINRIGIFPKALFKRPLTSSLKPTPLYYHAVRKFPAKILDCDIDLQRGSGIIIAEENQLARKLQLWKCVYVPWRRSVRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNS0</accession>
    <name>A0AAV4SNS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protocadherin Fat 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAT4</name>
        <name evidence="3" type="ORF">CEXT_518181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009713">
        <property type="protein sequence ID" value="GIY34022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="37"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY34022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16629" checksum="B73D2F2E3B4E698E" modified="2024-11-27" version="1">MTRTLFLQKEVYKTHVLEAAAITGARIRVKLSLDPPIHAYDQDVGVNAPLRYSIIQGNEKGLFEMHDQMADLYLVKEVDRESLKSPILTLHIQHETMIPQICHDPPPNGAATNPSLIHFWPSEESSLSLDAIQNHKSTAHLSFEPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STU9</accession>
    <name>A0AAV4STU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_604001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010218">
        <property type="protein sequence ID" value="GIY37783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18572" checksum="76CC88A74281949F" modified="2024-11-27" version="1">MGNVSSRFGSLEISKGAHSIRIFRRNKCGMVFVPVCNSREMNSPGPRDFKNKRNTLSHPHHVIRVTRSESTQMEYNHHFGLNFSPLITCKRVKSPTPHAKRKGGPGLCLFLVRVSDCNLARTVLMSKIYFISISKRKTRVPMNYKRYMSRLKGSCPNAHDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9S5</accession>
    <name>A0AAV4T9S5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_529761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010975">
        <property type="protein sequence ID" value="GIY43418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9S5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11224" checksum="A61CB916A104B3C5" modified="2024-11-27" version="1">MTHGFRDTLDPLIYYRGLFVFLNREPREVASINLPRYSVCARGRCLHRDPMMLCLVCQLVHARLPMPFDRHGQGPLCLGWRLLQRWENWNILMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFT3</accession>
    <name>A0AAV4TFT3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_150849_1</name>
        <name evidence="4" type="ORF">CEXT_776031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011162">
        <property type="protein sequence ID" value="GIY44564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="564"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY44564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="611" mass="64492" checksum="0AE03881FB0C33C1" modified="2024-11-27" version="1">MVVGSGGSELRISPITEIDIDFNFFTAEVRYQFGPPSRKIHFKVRAMAIDQGLVYPGAYIMLNMPTFVSLPSESITFKWYLEKEPNILPSNMQASPSGSVLTISELRKEQEGVVACAVYTNLGILATQKRFLIKQVDENNNKLIFTATRPPTRFLDINRWRKQQESRGWRIDGKRDASKSSQLRNERKKRSLQVNGFEMSDESPLNVQDLLETNTGFYYNQENQIGLSSNGQDNSIPSSRTKKSAPSRTIQSQGNRVNPNQPDLSYTIGENQSRRLNQFNNFADAKSQYNNGKPNRRFAPSVDLNLLRNNRQMDYDYNRMGGGIGELADVNMAGNVGDGGAMVGVTGGGMDGAAVDSGGIGGFGVADVDGAASGGMVGPGGVEGVGGGMVGPGGVEGVGGGVGGVGGNIGATGGPNIVAGIGASLEAVTEQVAGTVAKIGQETVINKDIGGKVGQGAAGNAAVGTGQGIVGGVDPSAGIGQSLISASVQQGMGVGAQQGPSATSDELGIAAGTITQGVDPIKIANPPNAQINMYPESLQGIAGIQTEISIPEVEIQERDLLSMLIAECSKDSQCSLNAECVRRPDKSGFCRCLPKFEGNGIFCWENYKFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJG2</accession>
    <name>A0AAV4TJG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_185121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011478">
        <property type="protein sequence ID" value="GIY46763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11913" checksum="90207204AB341F4E" modified="2024-11-27" version="1">MPFFGRRRLSKSNKLSGKKIKTKIEFSRRGSASRTGFRAFPPCISPGHNWFPNPQKRKKGSWKWKKEKNSCGPDYSWVGRHLQKGDLVLWRRLTPPLSVPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMF1</accession>
    <name>A0AAV4TMF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_637981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011554">
        <property type="protein sequence ID" value="GIY47254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10741" checksum="CB0621ED5DAADAB6" modified="2024-11-27" version="1">MRSAGCSLWSRIDSNPFPVPIPVAHSRNKSVRTSPVSGTTSKFQRFYTPDEPFASPLVFALTTMWRKKIKCFSFPFLCFVRENTVQKNWIRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQV5</accession>
    <name>A0AAV4TQV5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Spidroin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_253291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011721">
        <property type="protein sequence ID" value="GIY48520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1350">
        <property type="entry name" value="Spidroin domain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021001">
        <property type="entry name" value="Spidroin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038542">
        <property type="entry name" value="Spidroin_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11260">
        <property type="entry name" value="Spidroin_MaSp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spidroin C-terminal" evidence="1">
        <location>
            <begin position="231"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="340" mass="30534" checksum="2CCC6EBCEA07318D" modified="2024-11-27" version="1">MVQEVVVLQQQPGVWWRFWRRPRCWTRTRAVGQGGYGAGGGGSTAAAGGGYGSGAGGGQGAGGQGGYGAGVSAAAATSGAGAAGGQGGYGGQGAGGQGGYGAGSGGAAAAAAGGYGGSAGGGQGAGGQGGYGAGVSAAAATSGAGAAGGQGGYGGQGAGGQGVYGAGSGGAAAAAGGSTGGGYAAGGQGGYGAARATGGYGAGAAAGQAAGVRGGYGSGGQGGVGNIVSSTTSQLSSGAAASRISSAASSLAAGGALNVAALPSTISDLYSQVSSSAAGASSTEILCQVLMEVVSALIHILTSSSIGYVDLRIGVFLGCYSSSICYSCNGLAQMTSSFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TU14</accession>
    <name>A0AAV4TU14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_497801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011722">
        <property type="protein sequence ID" value="GIY48526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TU14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10688" checksum="66C89BAD4BCC07BC" modified="2024-11-27" version="1">MNSVPKKNRFANSHRINSKDTDPSPNSRVCTFPRVIRNESTQRIPQRKRNGNQKEIFGNSKTGIIMIDHAKKDFEKRSRKKKIRNLPDIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVK1</accession>
    <name>A0AAV4TVK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_593351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011780">
        <property type="protein sequence ID" value="GIY48980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8371" checksum="D4BE2DDA6C5537A1" modified="2024-11-27" version="1">MMSVDRGDHESNSLLPSRDLLYPSKGDIPKGFMNYIADLCSHETGLMVVSGSNPTYNYFDPLFPLPQRRERHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1W6</accession>
    <name>A0AAV4U1W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_271441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012158">
        <property type="protein sequence ID" value="GIY51771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15977" checksum="36EEE249A0BD7EA3" modified="2024-11-27" version="1">MLNARHVLFHEDVSSFLPRRAIDFVSDTQSAFNFCQSPSRLFHFFTAPYTMLQLKAWSFWREYPTRMRYTCFQKHFLIARKRNCFLRCNLLTHTYMRWLLDIIDGTIFEQYSAISILFCIMSLDLSATNYNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U571</accession>
    <name>A0AAV4U571_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012305">
        <property type="protein sequence ID" value="GIY52880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U571"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8875" checksum="AA4B19B129009835" modified="2024-11-27" version="1" fragment="single">KVARFLSEGGQNHCSFPPTISFRVFLTAWWAPHLRRRATTKALQNTHPFEINFENQLSGTECDPSVAAHLAKLALSAEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0N8</accession>
    <name>A0AAV4V0N8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_234563_1</name>
        <name evidence="2" type="ORF">CEXT_446501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013755">
        <property type="protein sequence ID" value="GIY63526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0N8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57277">
        <property type="entry name" value="Granulin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043371773" evidence="1">
        <location>
            <begin position="21"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14242" checksum="9E4F444B099AF7C4" modified="2024-11-27" version="1">MSSFGLSIALAFLLVVMTTALPNELMSALKDMPDLTQPENTMMGQSLKEIGVEICPDKLHLCPATAYCCQKEDGKWDCCPKTAANAPNNIFLGAGECCHQLGFIWHCCTPLHPNASGGDAGLSSDVHPTWICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V341</accession>
    <name>A0AAV4V341_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_580701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013815">
        <property type="protein sequence ID" value="GIY63990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V341"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11655" checksum="95461A468606D05A" modified="2024-11-27" version="1">MKLPFNASVLSRKLRKCKMVSFHLTCYPTTERNSLYVNENSAMSISLLNSKLLDDVCNGSSLHSAILFLDSVCTEFAPELQQPNDTVNEFRVVINSRRMVLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCA3</accession>
    <name>A0AAV4VCA3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_42700_1</name>
        <name evidence="1" type="ORF">CEXT_16161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014279">
        <property type="protein sequence ID" value="GIY67752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="46185" checksum="39FACE29E973625F" modified="2024-11-27" version="1">MEEMFTGEAKELGAKYVIKEINDFNELLSEQKTSDFLILDCTGRNSKLRSRMLGSDENNIVSEPLQHAMYINFKAIITTVTSLYQVMKNVPGIKLTEVVVSKNKDSDGFTNVTIPVFITKALAKHFDKEHPDINRNPLNPFNSSFAVSDKIFFPISSIIDINGKSIFKISEVLRAVGGKQSLYRQDFNFLLKCFKARREVVIYNTCSEIKEITVVFIIYNLVNQLGENITNVLHKVKRICTNEKFSNEEKIRLIKFTISNTFEKNSKELVLETAEKAIGLWPKLLGLRFDGNEVRLNIVLTLIKNELRACYRNCSQSTSIMGSTSNHEDSSESSNQNKLSIAVSEENLLLDDWVLVDSMQTIRESRRYRSQTNLTRVCKSIECAPIYNPTSEIWELKNKIKCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VE94</accession>
    <name>A0AAV4VE94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_186601</name>
        <name evidence="3" type="ORF">CEXT_806831</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014412">
        <property type="protein sequence ID" value="GIY68632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01018300">
        <property type="protein sequence ID" value="GIY98493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VE94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY98493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18839" checksum="A49B1DA03DA4EC76" modified="2024-11-27" version="1">MYEKSTIEFAETEAHSILAAGAMFARQREIYQFLEHEAFILMGSSKCSTFRLILDTSVDGTINHQIWRHGQPAPDHFLHYHPVQQYRPQCQPLCHQMYAVFETGNTETNDTDTANRYKSCRSKGKRRKNSTRKGCSELRSYPSPNFGGKYCLNGFHSLIPGHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUH2</accession>
    <name>A0AAV4VUH2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_66196_1</name>
        <name evidence="3" type="ORF">CEXT_402761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015166">
        <property type="protein sequence ID" value="GIY74080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21190">
        <property type="entry name" value="GH10077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21190:SF1">
        <property type="entry name" value="GH10077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY74080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="380" mass="42248" checksum="F17EAAE6FDB36FAC" modified="2024-11-27" version="1">MHGIDVDKVQQDRWPTAPGGGVYCDICQKFLCSKYFLKVHKQNVHHILDDSTKLSVVGSPSYNSNMSASEKKIDWHSNNFSQGIKLSSNVLNDSCLGSDDSKKRNNGNLFSCDICGQEFIDKVSLNFHLVNKHVKSSESKLYPSNVASPFSHSMEDSREALTNGILPCSCCSFINLDDSSKLSQLNSSDVKLISCSVCNVTYHQLDYYTHHLSHGISLPTVKKLPSLENGVHELNAGFNHSGNHMVDRNDSDKLQPRKCKRFRCSKCDKTFRTKLRCLHHIQVMHKSKKGFQTKNGTGLLGGKEINKLNLMVSGFKDGSLLPGSFQVPENSNVIMQPFHLSEPKPDGVTKQNVFVPSLVYLPVNQKVSETVTVAFTLTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W173</accession>
    <name>A0AAV4W173_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_158521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015369">
        <property type="protein sequence ID" value="GIY75619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W173"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13169" checksum="049D49254BC265BE" modified="2024-11-27" version="1">MKNIENKSPLWVSLTIDFTESRFEWLGDNEVLPNGQSIHTQRRTLMKNNENKKPLLGELNDWFHWRAVSNGREIMKSHRVDDPFTQRRYRSNVIGFPFLSVFVAELSSVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4M8</accession>
    <name>A0AAV4W4M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_311461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015658">
        <property type="protein sequence ID" value="GIY77652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13105" checksum="5CE562471C2B0311" modified="2024-11-27" version="1">MNFPTDDVGLSLPTDDVGLSLSTDDVGLSLNTDDFGLSLNTDDFGLSLPTDDFVKFANRRFSTMFGLSLPTDDVGFSLPPDDVGFSLPPEDVGLSLPAEDVGLSLPTEDVGIILPTGDVGLILPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WAF6</accession>
    <name>A0AAV4WAF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_511341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015863">
        <property type="protein sequence ID" value="GIY79228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WAF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11250" checksum="D48AC14D362CA65B" modified="2024-11-27" version="1">MDKRREKSAAKVVDMKVIDTKPNKMAVLLRLGFVKKKKTYLGGDLVLPCRSFVMLTNVRKKKKGIEKKKKREQLLSGCKIPGNSSGTKWKDLFFFLCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCK7</accession>
    <name>A0AAV4WCK7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_346161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015921">
        <property type="protein sequence ID" value="GIY79681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8458" checksum="C54E8EAC1374FE09" modified="2024-11-27" version="1">MSCKTIETSKKKDKADIRKQRHQLKIFPSNDFGLKDDKNISGDANDENDGNDMVIKMSEKSMVTNNHIFDDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCU8</accession>
    <name>A0AAV4WCU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_739001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015887">
        <property type="protein sequence ID" value="GIY79428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="289" mass="34071" checksum="05F1D7EC2A14DAB7" modified="2024-11-27" version="1">MEAELEHFAHALFFYEYGDFESFNIILYSLNSEESLALKRAWKTIKKMDGIYGKIFDYYFKNLNNDHFLYSKKDFAAFVLVRSLDICRSPSFYNFLLVVLFMCRLLQSQPRCLLLVQVMAKCLMIVYSRRYEDFFMANGGLIGMRKYFDEIKKEDLRSFISRHANSENEGILIPAFEDVFEIVAEFAKYNVVNFYMEDSELQYLYDSCYPFIDMQVVNGNLKFPKTSVALNIEDENSKIEYVLDKLNIHSEQAVNRVQTKCSYCGEKCCKYIMFQVLYRLHAMPGESIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WD57</accession>
    <name>A0AAV4WD57_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_14150</name>
        <name evidence="2" type="ORF">CEXT_553181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016027">
        <property type="protein sequence ID" value="GIY80582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WD57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8463" checksum="AE76F604BD833A27" modified="2024-11-27" version="1" fragment="single">IVGFRCPDQITGLSSKFYPFPRYPHPTDCQKLFVCVNDKPRLLNCGYGSALNLESYTCDALENVPDCNIRYKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WI76</accession>
    <name>A0AAV4WI76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016190">
        <property type="protein sequence ID" value="GIY81988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WI76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18895" checksum="A9D19D36302F4FF7" modified="2024-11-27" version="1">MIVTYREAFRHVGDGVFQEKASDAHCADGPQCVRERETGHTGRSGHRGRRISPHPFFSDETRQTCCQPYSSIARALPALNPFLILSSMKIRQHPLLSVSQPSFIKRSLYPRTDLVSLNRWSVTISLPERTGVSIEVLHHRFFSAVFTNNSRSRNGLRKLSQKLLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMZ1</accession>
    <name>A0AAV4WMZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_573071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016439">
        <property type="protein sequence ID" value="GIY83876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY83876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="10028" checksum="25AD128A19E6342A" modified="2024-11-27" version="1">MKEKEKEYSNWKRRDFDNEERQELEQEKLTEKKDPAEQRPFCFHWEGEEGGQRLEQKRTSDDLIEWNGKTRFSRSYAGDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WND7</accession>
    <name>A0AAV4WND7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016432">
        <property type="protein sequence ID" value="GIY83799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WND7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8781" checksum="4393133FD2203ADC" modified="2024-11-27" version="1">MSRRGNFWSRFLMGSSGRRWKVTAVAPRCFIVVIRKSLVPLGHPIPSMSRQGQFLLSFSDGSIGRSLKVTAAAPAVQCCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSF6</accession>
    <name>A0AAV4WSF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_199081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016659">
        <property type="protein sequence ID" value="GIY85457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16737" checksum="59CFDA34E683048F" modified="2024-11-27" version="1">MYTELPSPYIQSNLRWRHIVPPSNPRNTMYLRRVEGVAQKQITVVKRNESFKGVKKKRRALLRNVKDDIKDDTRGHDKVDKLCKNVAGVQVLAGALPGWGWGAPVITAAAVTGVLISEGATNDRSAVHASRSTDPLMGRSNRSGPPLCQARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1I5</accession>
    <name>A0AAV4X1I5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_569461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017089">
        <property type="protein sequence ID" value="GIY88676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1I5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="10574" checksum="4410B520D8AB7F9D" modified="2024-11-27" version="1">MKFIIDLKKFVIPSNILPKKPFSTTSSSVTVSMGIEVVLVVLVVAMGVGVVLVTIGCGFGGSVVIIPPPSVQGESTISTANPQKVLKIPLYNLTAGGVVKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8C3</accession>
    <name>A0AAV4X8C3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_673941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000021">
        <property type="protein sequence ID" value="GIY91521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8C3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13956" checksum="283D35A225DF7A10" modified="2024-11-27" version="1">MRRRSSPNISRNRCWVESMMGGSVLSLPECYTTTPFSQRNGKSGWYYRTSYWKRLSCSSGTESQFTSILTEDHRLPRNLVHYCARKEDEWTKRRCEELVKRDHAGNRKGDNQERDGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9C5</accession>
    <name>A0AAV4X9C5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_428361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017322">
        <property type="protein sequence ID" value="GIY90494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9C5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9440" checksum="9F5C2CFE499C6523" modified="2024-11-27" version="1">MKYALFLMNEKGEIRKIREILCDGPSKKMEGIISEISKAKAAANEFRRSLILQLCPEVHPLFRGLITPDDLGHGGEENGKTLSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDL3</accession>
    <name>A0AAV4XDL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_445231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017649">
        <property type="protein sequence ID" value="GIY93292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13563" checksum="F141105C10927BEF" modified="2024-11-27" version="1">MCLYTGISQDIARIKTAKLYLNLKLYLQYNFPSPFWKQSTFPLQSAAAAIITEKVNSPTLKKKGTSTANKPASELPASPPEYKHLLLMTPIRNSGSVTEPPHLHSGPREGPPISDPARPGGAPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFY0</accession>
    <name>A0AAV4XFY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017606">
        <property type="protein sequence ID" value="GIY92954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12120" checksum="CF46F8941B828CFD" modified="2024-11-27" version="1">MTICISFGIQVQGVWLSWKLCKISVGRSMAFRVLRSSKNKAEAERESVAAKESSASSDIYKPLRGLFQSRDGRYLIDCERKPHPTSVDEVNFAAWPYGFCIGAAITVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKB1</accession>
    <name>A0AAV4XKB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_25964_1</name>
        <name evidence="1" type="ORF">CEXT_140442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000538">
        <property type="protein sequence ID" value="GIY95530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15836" checksum="C8825ADE901D2662" modified="2024-11-27" version="1" fragment="single">MMNFNRRLSRFYSGNSILHTLSRTALHGEPCRSSFKNLHQTLKRLECYDALHLDNLLHVVKKLEETLLHWRPKKYDVLQLFWDLSKRSFDNDKRCRNSETAKLIRDLLLKHIIEVLQLFIASYTLLPKKAAGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLM4</accession>
    <name>A0AAV4XLM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Liprin-alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPFIA1</name>
        <name evidence="3" type="ORF">CEXT_404551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000607">
        <property type="protein sequence ID" value="GIY96012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048786">
        <property type="term" value="C:presynaptic active zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029515">
        <property type="entry name" value="Liprin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12587">
        <property type="entry name" value="LAR INTERACTING PROTEIN LIP -RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12587:SF15">
        <property type="entry name" value="LIPRIN-ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY96012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="27940" checksum="BFF43C48CF2868B1" modified="2024-11-27" version="1">MDVFFFEIFLSEQLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKEGPIGKALYGLMFSALISVCNLRIRPKIPINTEKDHNKFLAAGNSDDLSQMLRSRKLRVAIERVVALEEIVSQQNEELNQYKSMGFIRGHDDMKMKESLSENSKIANGNLDVGVEASKMIELQNIVEKQANEILVGRNKLLDYGGKVRELEENVTSSQKEIAHLKQEKQLVNKRLTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLY3</accession>
    <name>A0AAV4XLY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein RCC2 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rcc2</name>
        <name evidence="5" type="ORF">CEXT_560781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017819">
        <property type="protein sequence ID" value="GIY94743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028641">
        <property type="entry name" value="RCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207:SF1">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="125"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="160"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="212"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="264"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="340"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="441"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY94743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="512" mass="55980" checksum="2F23EB060D6C51CA" modified="2024-11-27" version="1">MNPKKRKADDDEGSDTKESFERQSIKSETADINASNYGSSECGNSTDQQKSDNGGSSEQPGTSNEQVPEEQCKDNISQSPEQRERKHIRLEGSKLPGVLLFSGGTNWDLIGRKELPKNAKGAVGRNLWGPHRIASLQGIKVTSVFSGSCAVHSVIVIEGGQAFTWGRNDKGQLGHCDNKRRDIPTMVETLKDHNIVSAACGRGHTLFLSERGLVYSSGDNKMGQCGIGSQNTAINIPTKITFKGRSICKVACGAEFSIIVDVKGGMYSFGCPEYGQLGHNSDGRYFVTSNKLSFRCELVPRRIIAYIEKTREGHVSLVDDVQIINVACGINHSVAVDAKKRCFSWGFGGYGRLGHAEQKDEMVPRLIKAFDGPRNVRGVKKVFAGGTYSMAVNELDVLFFWGQNKRAGEATMYPKPVQDLVGWQVRDVGCCNCSIVCVADESVISWGPSPTYGELCYGESRPKSSTTPQEVKPLDGIHIHSVACGYGHTLLIARDDTDEDRNKLNQLPEYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNX8</accession>
    <name>A0AAV4XNX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_238601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000563">
        <property type="protein sequence ID" value="GIY95686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12208" checksum="9F3E1AA923C3D051" modified="2024-11-27" version="1">MPTEPFAFGMRTLESKDKRNTQWSPDKRSSYHREKGSRSNCTHSRSLISHLNHPHVDLYIVSCKSISAVILASHSRSRRTLESNNLNIALGSKYPAITSHEFDTYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVQ1</accession>
    <name>A0AAV4XVQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_490481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018343">
        <property type="protein sequence ID" value="GIY98829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11594" checksum="6310C622953976C8" modified="2024-11-27" version="1">MTEVLCWKRYSSAENCYKLNSQVQWPLKQSQEKMHQKKNSDQCETDLHSEEDPATGRSLHFRECFDLEKWTCSFLLMREKKILSFLFLCSVLFGGAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XW68</accession>
    <name>A0AAV4XW68_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sleeping Beauty transposase HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_289021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001028">
        <property type="protein sequence ID" value="GIY99296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XW68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057667">
        <property type="entry name" value="HTH_SB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25787">
        <property type="entry name" value="HTH_SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sleeping Beauty transposase HTH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11507" checksum="E8304FEB72D004AE" modified="2024-11-27" version="1">MPRSSELSGFEKGIIIGYHKCGRSLRDISSDLKYPKSTVAYVIKKWKVSGDCRNVPESEDQRNWEIETDECSPEKFGRTTPNQWPSSVRSFNRHPGVLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWY1</accession>
    <name>A0AAV4XWY1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_371771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018379">
        <property type="protein sequence ID" value="GIY99073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWY1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10501" checksum="E4B7E45E120A7AE3" modified="2024-11-27" version="1">MICCCGYCLKLPFTPIASLQVNGIPSSGVSLAISSSDFTPLARNLSTFLASFKSVLVALVYHSVDVGMDLLGPLHVSFHDFFGAQLKRKNTQMSLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0X7</accession>
    <name>A0AAV4Y0X7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_794371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018621">
        <property type="protein sequence ID" value="GIZ01063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0X7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12261" checksum="64AF5A2812162603" modified="2024-11-27" version="1">MFRYTDDWNKKKCHSFPSIVGTLIHVTSEIALSIASSFHRLVSTRSRISPDAVVEIEEYFSPSHEGVKISITRRFQHPVKYRTGGVVVCFVLLPDAPFCSFNVGRKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2A1</accession>
    <name>A0AAV4Y2A1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_168401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001298">
        <property type="protein sequence ID" value="GIZ01422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2A1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13962" checksum="D1E800130A6370FE" modified="2024-11-27" version="1">MYGPVRMRSAFNRRGRPEPKPRVVFRTVDDLYVYLATEKVLYTRAKLANKRLNKVRACFGLSKSKQTIKSREGCRPIFKLRFIISKRHGHRGLILHLECGVLRRDLACIIHRKISVVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3J3</accession>
    <name>A0AAV4Y3J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_292911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018580">
        <property type="protein sequence ID" value="GIZ00714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10963" checksum="F75306B2BCA97B7B" modified="2024-11-27" version="1">MNENSLKCTLKCLVLYKKNTEAQKGVQYSGTPGATTIFSGTHKAFLAFCDDYVINEHSVKCTLKCLVLYKNDTEAQKDVQHSGTPGTNGIFWYKESLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y662</accession>
    <name>A0AAV4Y662_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_14741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018851">
        <property type="protein sequence ID" value="GIZ02742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y662"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12799" checksum="E08AA7E6255584FE" modified="2024-11-27" version="1">MESHSRSRALIEERSSKHAITEPVADAHSPHISPGTGTESCSRQFNSEGSRQKHYFRCQINYATKRKAIGRPATQLQKKRALRASETGEQLEERLEIFEYALFDPEEHCTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAM6</accession>
    <name>A0AAV4YAM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001571">
        <property type="protein sequence ID" value="GIZ03217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8417" checksum="9922E625846263B5" modified="2024-11-27" version="1">MESHDSSALSQWTMKSYYEWKGNSRWWKSEPGASLCSRKYDIHQMPSLSIPITHRAEHSEMIYPAKEQKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M2F9</accession>
    <name>A0AAV4M2F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_09582</name>
        <name evidence="1" type="ORF">CEXT_19891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019320">
        <property type="protein sequence ID" value="GIX66534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M2F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13691" checksum="E87C5206A6FF8A90" modified="2024-11-27" version="1">MSISIEEHLSPGRCQVTAMASVGSDLYIGTTWGCIVVAEGTTMRPVTVFRPFEEEVKAILPLLPRKPSDSKDPSSSQNTDCIPYIATVGKGYRNLIGRYASINAPALLQDNMFLLLWRADNWASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4I0</accession>
    <name>A0AAV4M4I0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_72361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019388">
        <property type="protein sequence ID" value="GIX67284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4I0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11324" checksum="F971B7BA010A61A0" modified="2024-11-27" version="1">MNRWKNSAKSPEYDEVRGMEKCSPSSNFSKGGERGNTDLSFGLFPTHVAARHLPFCFHFFCLQKRGVFGSRRLLGLHGQHPSRIRPRELQFIVNLTDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD22</accession>
    <name>A0AAV4MD22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_710471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019618">
        <property type="protein sequence ID" value="GIX69798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9427" checksum="FD18442386EFDD4D" modified="2024-11-27" version="1">MATSSPLGSVLCHLSDVFFWPNISLPDMSNRIAAGILVKRRRPVSKVFLKKIQRTALLARKRRFSVLEYKFSGFVLSTFRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLD4</accession>
    <name>A0AAV4MLD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_505761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019830">
        <property type="protein sequence ID" value="GIX72281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10003" checksum="8B78D5DACCFCD0D7" modified="2024-11-27" version="1">MSMCGDGMDRSSQSRQIYLRHVENQEPRTQSNNSEIPLPQIIFVDLPDGAPAMQINTSLEEETQTRGPTRQTLTAAFKCRVFSPQIIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN43</accession>
    <name>A0AAV4MN43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_775351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002291">
        <property type="protein sequence ID" value="GIX72209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7988" checksum="A6C4F42EE82FBE0E" modified="2024-11-27" version="1">MSQSGSREDLEGGLSKCDIALSGFCARKRLMFLYVCWFQVLVTVMQVEEKKCCVMLLMGRFLKDEMPGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR63</accession>
    <name>A0AAV4MR63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_79333_1</name>
        <name evidence="1" type="ORF">CEXT_678871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002535">
        <property type="protein sequence ID" value="GIX74890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12407" checksum="FCF9CFEA18F39B62" modified="2024-11-27" version="1">MFLRNETEEQNESLIHEIPYNENLPSSSSNTEQIIVFPYVGPPGAGPGLLGSKPGSGKLEYLVALERHANSLKSALAIAATLNGLKNRNVHEEVVCNSICNIENEDLARYRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MV27</accession>
    <name>A0AAV4MV27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_499841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020245">
        <property type="protein sequence ID" value="GIX76330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MV27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="14178" checksum="A7F85BDF6879370D" modified="2024-11-27" version="1">MEGKKKRKKTTQKKTNRRKRKKNPITMSFLAFNVGLETSNNRKQFSPLAFQSENETCATTLRRTHSWRSFHYLMGAVIERNKGRWENARPDMIQKIRAPLRLGHRRFPANRGASSESRWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N160</accession>
    <name>A0AAV4N160_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_182301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020419">
        <property type="protein sequence ID" value="GIX78520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N160"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9921" checksum="DD09962145051954" modified="2024-11-27" version="1">MKVERRHLGKRTVLVDTVHKKANEDYQFSKGFEGTRKLFYDEESLVEKILRRSRFWFQRLLVLEDGCKKRFAINRPSSKIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2J1</accession>
    <name>A0AAV4N2J1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_776231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020363">
        <property type="protein sequence ID" value="GIX77876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9639" checksum="6F10DB0FC5A813E9" modified="2024-11-27" version="1">MTRNRTKTLLGIYLGSGFLDFANQISKQCVTLSPFAGHRATTPDVPRAPFATDTTPPPHGLKIDLWTIFCIKNGPLWKKTLYRMTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAQ9</accession>
    <name>A0AAV4NAQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dscam2</name>
        <name evidence="4" type="ORF">CEXT_482771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020605">
        <property type="protein sequence ID" value="GIX80564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007417">
        <property type="term" value="P:central nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000104">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF53">
        <property type="entry name" value="DOWN SYNDROME CELL ADHESION MOLECULE 1, ISOFORM BQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="103"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="222"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX80564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="280" mass="31344" checksum="0B735627CF967F0B" modified="2024-11-27" version="1">MRIPPRWIIEPSDTSAVAGRPAKIDCQADGVPLPHVRWKVSAGEPPEKFKTIVSSSHVHILVNGSLNFQSIETSDSGFYLCEANNGVGTGLSTVVRLSVHSAPQFHSKYMLMASRRGERATMECRALGDKPMSFSWKKNGVILDPVAEVRHMNTSFFLQIFTAFRGHSIGRSIKPHHRESREKDSALFTCSAVNDYGEDSKNIQLTIQGKTSLNRGESIPDAPQSTEVHDVSSRSVRLSWSKPFDGNIPITQYTVMWRQVGVHFRHMIEYEQPETTRNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE55</accession>
    <name>A0AAV4NE55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_251541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020824">
        <property type="protein sequence ID" value="GIX82981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="16517" checksum="2BD1350EFB5D20CA" modified="2024-11-27" version="1">MYNILQSPDIHGSAVLPPRNAHLKGGSPPPHPPPRVVDASGLSLALTDGLGEFDYEVGGGVFQEGMRILVTSFARPIENNNIRKRAKNVCFGCISPISKKKGNVAIGAMIRKDLIILYFQYGSCPHSFRAAPSGSREAEFLRNNDAESNAKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLI6</accession>
    <name>A0AAV4NLI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Orct</name>
        <name evidence="6" type="ORF">CEXT_182991</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003441">
        <property type="protein sequence ID" value="GIX84596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX84596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="24298" checksum="E9CF518538066E31" modified="2024-11-27" version="1">MRGSESVHVLRFVIHNNDLAGNPYLNFFLAGVLEFFLRNPILGYQEEGFGDPPIALMMVGGIACAAIALYSTKLSWLSTSFAMVGKFCVTGSFGLMYLYTGELFPTVVRNVTLGSCSMCARIGSILAPLYGTARTYREGKATHPAVPNILYGLLALSSGVLAFLLPETRDQKLPDTLEEGENFGKLMELESPEDSEKEAVIEYPLEDFSESTGEENILNETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NN77</accession>
    <name>A0AAV4NN77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_658011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003469">
        <property type="protein sequence ID" value="GIX84989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NN77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12786" checksum="90D12E77C3086F47" modified="2024-11-27" version="1">MVPDQVFCSFWTSNRTKENILFSHPITNNITNDTLIEEVVATKVEAVTIETISLRDVSGIKLQVAGWKVVKFPNWSCSLRNPTSDTELNDPMPGMETTTLWICLPYSYFLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRL6</accession>
    <name>A0AAV4NRL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_114221</name>
        <name evidence="2" type="ORF">CEXT_467851</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003673">
        <property type="protein sequence ID" value="GIX87328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01000473">
        <property type="protein sequence ID" value="GIY95024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8741" checksum="7E99F923FC4ABA1D" modified="2024-11-27" version="1">MDHGGVAAAFRKHHVRKKLCMSEEKAEYLDSKERACSCLHESTSTEQQVSEIRSIKQDIKTLPLVESMKIAAAFSDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NX44</accession>
    <name>A0AAV4NX44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_296481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003847">
        <property type="protein sequence ID" value="GIX89308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NX44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9436" checksum="CCF51A06E0928BFD" modified="2024-11-27" version="1">MTSGLFVKILLHRISGGPSIKITALNSSPLTAVASHASNSKLWNPAPEHSDAFDPRGGAYKNDFRHCNLMKGFPHFRYPTEHACDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P357</accession>
    <name>A0AAV4P357_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_135587_1</name>
        <name evidence="2" type="ORF">CEXT_548662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003940">
        <property type="protein sequence ID" value="GIX90425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P357"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="454" mass="48447" checksum="49C129234A134D2A" modified="2024-11-27" version="1">MSKLQLPRRSPTLQCSMPKCDPGCTIDYSTKPCPGCSCGGEGGVQCSTPKCDPGCTVDHSVKPCPTCACGDSTPAWQCSPVKCESHCQQVLGPQGCPTCKCPSCTPPRCAEGCWVDTSAKPCPTCICDRHQRRYAVQLNVFSDPFCRTLKCGPRCERALAPSSPTERCPMCLCKGRAGQQLTCAAMRCELPCRFERFSEHGCPSCICNPIPCPEIFCPPGQAPVKSAWQRCPVCQPIEFEGPPAIQCSMPKCDPGCTIDYSTKPCPGCSCLGPPLCSARCPNAIPAAPSTTPRSPVPAAPAPQVFLKFSVAFRDVMPAAPSTRPRSPAPPASAQTHPRSPAPPASAQVFLKFSVAFRDVMPAAPSTRPRSPAPPASVQIFLKFSVACPGAMPVASSTRQRSPVPPASAQAHEICPELAMAMILISGNEPFSLLRKKKHHLLKELSVFLPKHRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4N5</accession>
    <name>A0AAV4P4N5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_347201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003976">
        <property type="protein sequence ID" value="GIX90935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9482" checksum="8AEF83A69C218EB7" modified="2024-11-27" version="1">MFDVPCSRVGHIYRKFAPFPNPGMGDFVGRELEEKYFSEKRVGNNRLFVYLEKTVEIKETQTTTRFIKLFCFREGETTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAK6</accession>
    <name>A0AAV4PAK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">THAP-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_31580_1</name>
        <name evidence="8" type="ORF">CEXT_391931</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004357">
        <property type="protein sequence ID" value="GIX94297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.210.20">
        <property type="entry name" value="THAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026516">
        <property type="entry name" value="THAP1/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006612">
        <property type="entry name" value="THAP_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038441">
        <property type="entry name" value="THAP_Znf_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46600">
        <property type="entry name" value="THAP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46600:SF11">
        <property type="entry name" value="THAP DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05485">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00980">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50950">
        <property type="entry name" value="ZF_THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="THAP-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX94297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="20400" checksum="477B7C70C5B324E5" modified="2024-11-27" version="1">MHTTYDLWQVTSPMKALPLKFLTKLQLFYIFIKSDKSGIEFLNIKMVKKCCVPCCRSNYDPTVYISCFQFPKEEDRRNLWLKKINRKDYSQSSKNTVVCIKHFSEKFVITEDHAVRNDGSVLTVKRIYPKLTPDAYPSIFPNEPAYLSSDPVSKRKTPSERRNEILKRDEKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBK2</accession>
    <name>A0AAV4PBK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_707711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004265">
        <property type="protein sequence ID" value="GIX93546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10280" checksum="88C0973FB43349E4" modified="2024-11-27" version="1">MQISNTFDAKANLISEKPTLDPRISPGRELCKAIRPFLLLGREKRLKWPSPPSHYPLASPKEFILPDFSSRGRSILTAASAAHLEGISALKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PM03</accession>
    <name>A0AAV4PM03_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isocitrate dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Isocitric dehydrogenase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NAD(+)-specific ICDH subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Idh3a</name>
        <name evidence="8" type="ORF">CEXT_437031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01004618">
        <property type="protein sequence ID" value="GIX96207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PM03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX96207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="247" mass="27211" checksum="9E53D0B6BB2351D5" modified="2024-11-27" version="1">MTRHILSTPGGQVSIEWEIEDVTPVRGPDGRFGIPQRAIDSINKNTIGLKGPLETPIGKGHRSLNLAIRQAFHLYANVRPCRSIDGVETLYNDVDIVTIRENTEGEYSGIEHEIVPGVVQSIKLITKEASHRVAEYAFEYAAKNNRKTVTAVHKANIMRMSDGLFLQCCRQVAEKHPNIKYEEMYLDTVCLNGISLVVLPLIPSGQQEICSDVNVTGIIRRTKAVKRVNSISCGGNCAEAGEVEEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTN8</accession>
    <name>A0AAV4PTN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transport and Golgi organization protein 2 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TANGO2</name>
        <name evidence="1" type="ORF">CEXT_92281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005224">
        <property type="protein sequence ID" value="GIY00793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="302" mass="34033" checksum="887BC2FBC2DA2AF3" modified="2024-11-27" version="1">MLGQSLKSVLLQEQILKMCLLTFYLNPDAGKHELYLVLVNVRDEIYTRPTQLASFWEKHPHVIGGMDLESGKEGGTWLAMSKKGKIGALLNILQPDEEILPGKKGRGFLAVDYVVDEKNCTTYLEEISSQGVNYNEFLLVTIEFTSLNVPKIACYTNSSSLPPVSLQPGIHAFGNSIEREKPWPKVSKMKEMFTEVVKKYPSVSTKQTLVDELFSLLQDSTRHTVDDNMKRQGKNKSSAFLEKLGAIFVNIPESNYGSRCHTIILIDGSGNVDYMERSRSENLQSEGCDEWHTNHHIFKLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QLJ3</accession>
    <name>A0AAV4QLJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_589901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006229">
        <property type="protein sequence ID" value="GIY08313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QLJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9576" checksum="965F11C60D9569D7" modified="2024-11-27" version="1">MNGNSLEVRESTAPDPYSVFNKIPGGKCVLSFKGDSIKRVKLGEGLVYKVSGESACSFCFMFSEWRLNDDKWDRFQKRCTIKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWY4</accession>
    <name>A0AAV4QWY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_247161_1</name>
        <name evidence="1" type="ORF">CEXT_617471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006757">
        <property type="protein sequence ID" value="GIY12213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051521">
        <property type="entry name" value="tRNA_Mod/Golgi_Maint"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15627">
        <property type="entry name" value="NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15627:SF8">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11459" checksum="A880592C93404C0D" modified="2024-11-27" version="1">MAVSEMRGLISPKPALHRAFVVQVSVLAILQEKLDTHLSTIEAIYYFLVELHGLMHPEVPYDGEYDNMLFFFKFMYFKIRTLYDPLKLKAYRNGDPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QX33</accession>
    <name>A0AAV4QX33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_117701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007003">
        <property type="protein sequence ID" value="GIY13822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QX33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9861" checksum="467AFDC70BD471E4" modified="2024-11-27" version="1">MHKGEQELSIKIWAPTSSIMLSQQGSQHPDWSILRLPCVGSCTEAAFNKKPSSRILPFQLCWTSMAIGSPPADQGAERVLPRTPWTHCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0Y6</accession>
    <name>A0AAV4R0Y6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_769531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007024">
        <property type="protein sequence ID" value="GIY13961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0Y6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11037" checksum="223006DB280AE7B4" modified="2024-11-27" version="1">MKLPELSIHCIKKNSLQRKNRKNKIAPAILPKPLIPLPSEDDKTDKMKKVKVQIILNTSTDQHLSKGYLRMLFLIKVPHAIKHQKNSGRRNFCASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1Z5</accession>
    <name>A0AAV4R1Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_472641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007126">
        <property type="protein sequence ID" value="GIY14649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="33600" checksum="74D5332688CD6595" modified="2024-11-27" version="1">MAELLEAAMPFQAGKGTGKMDLPGIPEEKLLVLDCIVVWSIKTRLKNKEMVSLILKIIPILTHMDEEQRRNAINSGICPPEPSTRRQLPNLDHRKQNAPINLEQGLPPPILKHMPSLSDTSTYTEGRNGGIPRTVPLTSLAQTLEQQQDIRVTTKRNDQYHEPDNGTSQGWREGRRNKPMPPEENFQDLEGYQDEEEEQNIDDYFEMIEKAISRPQQQTIAGGKKSAEIQRQLLNREPETGHSIPGSSDFGSSKGQVSAVLRQIDAYNKIICTKLKTLSSSSKTYSTSYEQKEIHQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8A9</accession>
    <name>A0AAV4R8A9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clavesin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CLVS1_1</name>
        <name evidence="2" type="ORF">CEXT_221701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007535">
        <property type="protein sequence ID" value="GIY17710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8A9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15593" checksum="BBF810AC57806E9D" modified="2024-11-27" version="1">MSIDDFTRISLFTAAQALRHPLTQMAGFRFIVDFKDTGFRQIKYCTLSNVKLIYLSGMECLPVTFKSYHVINGNFATKFLWAVMKLVLPASLRNMFNFHSSTEELFDFFPRSIIPKEYGGELENYFHGGLAQTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAG0</accession>
    <name>A0AAV4RAG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_46586_1</name>
        <name evidence="1" type="ORF">CEXT_427181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007573">
        <property type="protein sequence ID" value="GIY18029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17719" checksum="DDD190D3AFDD16A0" modified="2024-11-27" version="1">MEQYLKDIINKLEGKSQVSLDVTKWKVQGMIRDMKLQMQQMTNRFQVKDNLARCIEKMEEVMTTLVNVYGRIQVYQEQQSLANYIADISSTAANDINISKPELVSALNELEIHIRSNLVLKQYKTAVDAFKQWVFPFAHTFFGNIHAAIAFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RH93</accession>
    <name>A0AAV4RH93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_194491_1</name>
        <name evidence="1" type="ORF">CEXT_121521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008049">
        <property type="protein sequence ID" value="GIY21698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RH93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="262" mass="29340" checksum="573FCF8C61C1772E" modified="2024-11-27" version="1">MAKSLSSRSELKAITESEFSIAFETALDLVGTKASMQAYSENFSSEISKLLGKKRLLLEASLKEKADFIANVIVHGLPMEKVSPELKTFSQNLGENNNADVGFCERNVFGETESIYKKKYAAAFAFEIAHVFDTYEILSWDKIREYVESISQAMLSGLPADISTKEEKQANNIIHKEQDNDTLSNLSLRFGKQKENLTSIDILEYQLLTSELFNETFNGSMSFQNSFELAEVVSQAVINISESKIVGKLTYSLPYYAAIRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RL32</accession>
    <name>A0AAV4RL32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_119991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007953">
        <property type="protein sequence ID" value="GIY20975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RL32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20073" checksum="F28250E13204158F" modified="2024-11-27" version="1">MVPVEIALSCLRDPSSACITVDITGERFTDKNYRTNRWIFRNQSKLPFPYRGKYSLDTARANIQQLYAQKDAGRGLYTEVLGDCPKYDELPTPSEQLNKPCEIHLAGDDYRCSKRVAFAFARYLESREGDQLLVLQPDAMDDGDAVNESVIIEMNRDATKPICFVKNNIHFTILLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMJ9</accession>
    <name>A0AAV4RMJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_237651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008221">
        <property type="protein sequence ID" value="GIY22939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8717" checksum="37C7D4132DC8825A" modified="2024-11-27" version="1">MIYLNPGRRDLTEPLSLPLRILVGNCAHKSGIYVRGRNNETPGCGNSPGEYIKLAQKPVICHGPHPLSRMRTGHSTRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMW1</accession>
    <name>A0AAV4RMW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Bone morphogenetic protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Bmp1</name>
        <name evidence="14" type="ORF">CEXT_678731</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008227">
        <property type="protein sequence ID" value="GIY23055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005041">
        <property type="term" value="F:low-density lipoprotein particle receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000005">
        <property type="entry name" value="Procollagen C-endopeptidase enhancer 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF5">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CUB" evidence="12">
        <location>
            <begin position="38"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="13">
        <location>
            <begin position="180"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="368"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="446"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY23055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="554" mass="63401" checksum="4958E08689493006" modified="2024-11-27" version="1">MKIHLQSCFRNSRSRYRGFYARYKSVECPGCGVGDFQCSELHVCESPCGKIVSIGHPLNYQNNHRCRWLIRTEPSHFINLTLQDFDIVGGENCQYDYLAVYDGDTIQKSSLIGKFCNMKKPPTEIVSSWNSLLLEFSSDAETNGRGFSLKFASKNFQMPADIHVYDLDDELACPPPWKYYNGNCYNVFHADDAIQWYEAEDRCRKIGGDQNGHLVSMTKQKEGVYRWSDWNPMIYTDWASAGRSLRTQPDGGAYQDCTMLRVDSGHPTAHWHDIPCSLGKLAFHNWDGIDWGDDDPNKAGNENEVLSSISDYICKMKSDRPAGNVELIKSIPAQIGGTAAVPMLPSASAAEKYFLCRNKEIISTQFVCNLAEDCRDGSDEETCSLKECPKSSFRCHNTKCVSIAAYCDYKDDCGDLSDEFRCQHRECLPGEFQCRNGQCIPEEQRCDLLPNCYDKSDEHDCKGFCNPNSTFQCYDGTCIPRYTLCDGHRDCPGKYHEDEQYGCSRREDRDGRNEEKNYAPKEENMPGSLHIGQHSYQRLLHHRLRWYRWSYSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNY9</accession>
    <name>A0AAV4RNY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_121621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008049">
        <property type="protein sequence ID" value="GIY21708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15147" checksum="48ABE1FE959E7E16" modified="2024-11-27" version="1">MNHKERLFLFLPEPRGRGKKPPAPAKPTNEQKPVPLHRKQGGKKAEKADADGFRAPPKHMTKVPPPTGNITPTLPLTNPSLEMADEQPEQSARKPRIQPFFEERLDSKPIHVTIYHSIYEISPIKEQFFITHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RR53</accession>
    <name>A0AAV4RR53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008369">
        <property type="protein sequence ID" value="GIY24225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RR53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12020" checksum="E350718B1C57A7E1" modified="2024-11-27" version="1">MEETRCVSLIFFWVGLGLLAQYLYLHTIWSFIHLLFYTELMTITVKENGGLRDLISGLDRWAAESSSPTSFLGITILALLCLYHFMGISQHLPTNNILALLCQNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWU7</accession>
    <name>A0AAV4RWU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_273361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008629">
        <property type="protein sequence ID" value="GIY26119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13620" checksum="766CC879282B96B4" modified="2024-11-27" version="1">MTVSKHEDTAWYMRRDQMRSTTHNYLASLVPQRQTNQALNYDKPRITGPFSIDPTTALFCLLGFILAWASSPPFNSEHWVIAASTDMWPGCELPGQADMIHKCKTHSCDCWKEARPFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYS8</accession>
    <name>A0AAV4RYS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_529331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008475">
        <property type="protein sequence ID" value="GIY24993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="14482" checksum="C7413E388243583E" modified="2024-11-27" version="1">MLQWKGFLKKYHGLPVVSMCSTIPSLFLLVLLHFFLRELCKWFKEMVQNENLVRRRKAYYLLVHRNIKRKKVMFLHVLCHRDTVYKSYQEERDLEKKVIWERFVIVFMIIICKWKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZ88</accession>
    <name>A0AAV4RZ88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_208151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008727">
        <property type="protein sequence ID" value="GIY26755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZ88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14485" checksum="D58CF20879F21411" modified="2024-11-27" version="1">MLNIIHINSKLTNKNILSFKETQSTTSLFPKSISTGNTNVSTTTHSLLFGSRLKSTPDSLRKLPRGSNAIYYYLPDNVSPVTSAGDTAAALLCPAGKKKPNLCRGKKNHCIGDLWTAAKLTISLESDTHSPLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZL9</accession>
    <name>A0AAV4RZL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Rbp1</name>
        <name evidence="4" type="ORF">CEXT_766462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008745">
        <property type="protein sequence ID" value="GIY26890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12373">
        <property type="entry name" value="RRM_SRSF3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001074">
        <property type="entry name" value="Splicing factor, arginine/serine-rich 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="69"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY26890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24269" checksum="10EF9B76F06A4B62" modified="2024-11-27" version="1">MLVNTDGLSLIEPIHRKLTKGVVLSSDVSFKIEASLPNIQERSETCCLAILLIYIFVMTRRFSDWDLDCKVYIGSISTRTTKDDIESLFSKYGPLRNVWIARNPPGFAFVEYEDRRDAEEAVAELDGVRLCGQRIRVEMSHGKTRRDRRSDTRRSPPQLIHQLLHKAASLISNFQRNYILPSNILIKIWPFRTTHSSHCASDVNSNSYINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZX9</accession>
    <name>A0AAV4RZX9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_813321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008760">
        <property type="protein sequence ID" value="GIY27010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042778">
        <property type="entry name" value="ZCWPW1/ZCWPW2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999:SF2">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="88"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY27010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18307" checksum="71B0CB352BE11057" modified="2024-11-27" version="1">MEIDLEEMDDVIKGVAGSRTGCRSRPSRSYALSPRSKSRNPRKSAKVGQQCKTKNEIRGEKKKTDSGEPSGEDAGETRRPDQITQYVPGDLISAQMKGYPSWPAMIDIERQNGIYFKIIKENTHYNVRFFDEPVTRAWVAKESIKELRIKIIVSIFSPRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S604</accession>
    <name>A0AAV4S604_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mpv17-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mpv17l</name>
        <name evidence="7" type="ORF">CEXT_373501</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009016">
        <property type="protein sequence ID" value="GIY29050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S604"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF85">
        <property type="entry name" value="MPV17-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY29050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="21850" checksum="5E3385D4FBBC6985" modified="2024-11-27" version="1">MSMLGRTKLLFQKHPFLMNVASYGTIYVSAEVAQQSLRILKESKTKSIDWTNVGRFATIGIVGIAPFLFTWYRCLDYVLPTVTKIVVAKKVTADLLICSPTTITIFFAGMGVLEGREDVFAELKAKFWSTYKLSCCFWLPAQALNFALLPPYTRVAFVGVASFIWVNVLCLIKRQEFADPKKENLELTEKAGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8A3</accession>
    <name>A0AAV4S8A3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transposase IS30-like HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_263734_1</name>
        <name evidence="3" type="ORF">CEXT_65231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009093">
        <property type="protein sequence ID" value="GIY29594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase IS30-like HTH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY29594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12187" checksum="4C1AF5F376795165" modified="2024-11-27" version="1">MDLKGKEITPEERKIIIKLRNEGKILREIGKIVGRTHSSIQRVINNYASSKSIISKPRSGRPSKLTAREKKYVFKSVRLNPRISAFQIANDVRQRFKKKHFMKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SI20</accession>
    <name>A0AAV4SI20_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exosome complex component 10 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">EXOSC10</name>
        <name evidence="12" type="ORF">CEXT_14871</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the exosome component 10/RRP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009604">
        <property type="protein sequence ID" value="GIY33202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SI20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071044">
        <property type="term" value="P:histone mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071040">
        <property type="term" value="P:nuclear polyadenylation-dependent antisense transcript catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06147">
        <property type="entry name" value="Rrp6p_like_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000059">
        <property type="entry name" value="Exosome complex exonuclease Rrp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.80:FF:000001">
        <property type="entry name" value="Putative exosome component 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012588">
        <property type="entry name" value="Exosome-assoc_fac_Rrp6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045092">
        <property type="entry name" value="Rrp6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049559">
        <property type="entry name" value="Rrp6p-like_exo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124:SF47">
        <property type="entry name" value="EXOSOME COMPONENT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124">
        <property type="entry name" value="POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08066">
        <property type="entry name" value="PMC2NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="HRDC" evidence="11">
        <location>
            <begin position="447"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="624"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="691"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="646"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="737"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00070365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY33202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="785" mass="90548" checksum="134D6077493126F0" modified="2024-11-27" version="1">MEDNVEEMTDHPFFIPGYTDANSYSQAALRSILLATKASNELPTADNDFNICHLYPGFQEVLNHEKKEILSFMTTIIQSHGISGKFGDSTPEENFDLVAQANDVIQEIASTYLDEAAGLKKSEEELITAIKPTSAINTSWNKSPQSYKLLTAKIVTRSQQYFKDKIDNSNSPFVPIITEKPHSIKPLAIIYESDKDEFCHPYEWEIEKFSPQEEDLQTVEPVFPKPLEDTKFIFVKTEDELKKMCETLNKEKEIAVDLEHHSYRSFQGFTCLMQISTREEDFIIDTLALRSELFILNEIFANPKIVKVLHGADMDVQWLQRDFGVYIVNLFDTGQAARVLHFAHLSLAYLLKHYCKIDMDKQFQLADWRIRPLPEEMIKYAREDTHYLLYVYDCIKNDLIKAGNDMKNLLFSTIERSKTICSKKYQKPLFTEDKYLELYGKSKKVFNAKQLYCLKELYEWRDKIARENDDSLAYVTNLLYFNRYVLPNHIMLQIAEALPREQQGILACCNPIPPFLELLELKQKAQVTKSVHSNIDLNSLIHCPHDIHHLEDKKSQSFDQSGNAESLLPFITKKHSSSSLLKEKPILSFTVPMNEKNIPEQVVKVLKTLISPYERYQITKQLQAKESSTKKIIEDTNSRVREENIETSQEQNDSMNSAENNDSIVEEEDIEINDEKNTTAEISTPSVLDDDIELAPLRKRKNKNKKRKSLTSFEPHGPPAKKKSCSPVMKKDIEVVTVDDDDDDEFTPYDYSKADFSSFTGNKNKPNKEKNNKKRKVIKFCSSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJ09</accession>
    <name>A0AAV4SJ09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_712751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009721">
        <property type="protein sequence ID" value="GIY34080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJ09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11730" checksum="B60D3107674DD331" modified="2024-11-27" version="1">MCKPKYSASKIVDLIFTTKNKITKDYSLREELLINLTLKSLEKKKRKLCKKRRVLSLESVNAICQPRIDYSQLPEDDDPLGLNDFYSNLKSTSASTTEEKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYS7</accession>
    <name>A0AAV4SYS7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_741091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010282">
        <property type="protein sequence ID" value="GIY38286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8409" checksum="4EEC7D1B7C085708" modified="2024-11-27" version="1">MPLARENWKSTRRIMETRSPTLPATVQRVIDILDATSYHIFIQQSCSLSQNALPLHGGLLMNTPDLQVNTEFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZ82</accession>
    <name>A0AAV4SZ82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_301601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010455">
        <property type="protein sequence ID" value="GIY39360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZ82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12342" checksum="4AA62744F4D6D594" modified="2024-11-27" version="1">MQSNPKRAARQSANNCKCLNSDWRAESPFRALSGSRESNICRKKEVIVLLNNFFPFGYPPAGLKQIDSQNLLLLTGRLGDVFFLTIPFSPGTANYIFHISPVFLPDCSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0N0</accession>
    <name>A0AAV4T0N0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010436">
        <property type="protein sequence ID" value="GIY39254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0N0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="43635" checksum="F2FE7A63584B2917" modified="2024-11-27" version="1">MAKFVNELKNINLEYKRRELSLQESVNELTDRINTAAKIYKAQFLLIEKLNRKLKKLESTPSTKDAAQNISDSDTGEHVLGKAASLLNKETECQGTEKSLGARPKLKVFRRTRLFADNVFSGLHTAPIRSDNTINPFTNKPASIPPSTISIETKNATSTADIRTDPIRIVPTNLENISSFPVNTETKNQISTVDKGIDPIRIVPTNPTSIPSSTINVGINHSVSPAKSGFENKVISEKDILKDPLKFLPRYVHFKNHGRPPLPHILTVVKEKEDAMKNMIAVKNMGAIQNMDAMQKVLTDFFFQLRKGPAKEELENKVEELHVMLFCNACNLSFFLNSEKCPFKLLEHLEKEHQLRTCFICGQMFDESVPMKYFYYHLDNHFGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T385</accession>
    <name>A0AAV4T385_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_672941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010499">
        <property type="protein sequence ID" value="GIY39716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T385"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9494" checksum="950631862FD9E4DD" modified="2024-11-27" version="1">MSNSVFGLKRKTSKIKSFRVLVWLSDFSGSRNPVMVTASLCDAIDPLEFYHGSWFSEIGFSVSSVCIQEVLEVRNTCALGFTLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T974</accession>
    <name>A0AAV4T974_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_637131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010947">
        <property type="protein sequence ID" value="GIY43223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T974"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043932545" description="Secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY43223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12145" checksum="07AE759D81174F0D" modified="2024-11-27" version="1">MSAGCVIFFFLTAGSALSEHLCKLISVSSFSGVLNTIFCFSDDQRTRECCFMTLQWKRIVFLVHPFSLWIAFLNFCAADNRTPLMQSGGRRPRSQAISKHSEIKNEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGY5</accession>
    <name>A0AAV4TGY5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_746661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011135">
        <property type="protein sequence ID" value="GIY44386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10196" checksum="952D1FC58DFAC3D6" modified="2024-11-27" version="1">MKIQNSLRMLRNLPTLLKESLFSPTAVDNAEQLQSVSVKMKVQSGKLCYLIVIVLAFINLCFSLRMEFDEDDDENVYDDDYALINSQVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNK6</accession>
    <name>A0AAV4TNK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_6001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011466">
        <property type="protein sequence ID" value="GIY46696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8509" checksum="2CF8728BCFFCD5EC" modified="2024-11-27" version="1">MIRSDPFRISPDLGVQRDRLMSSCHHANTCIVMNFSGQARDSVIQNRGSGCACLFFREWNFFTLREFQRTVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TPT2</accession>
    <name>A0AAV4TPT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cadherin-related tumor suppressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ft</name>
        <name evidence="10" type="ORF">CEXT_339251</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011583">
        <property type="protein sequence ID" value="GIY47456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TPT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000033">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026">
        <property type="entry name" value="FAT ATYPICAL CADHERIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026:SF125">
        <property type="entry name" value="FAT-LIKE CADHERIN-RELATED TUMOR SUPPRESSOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="11"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY47456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11745" checksum="C773BA96FE698B35" modified="2024-11-27" version="1">MDENDNTPAFLHQQYSATVSENTSVGLSVLQVFASDADEGLNGQVRYSIIAGDLNHDFVIDQDTGIIRVSKNLDYERKSLYSSRYRLRTAGGHQARHRLCGDCNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVL4</accession>
    <name>A0AAV4TVL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_550761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011909">
        <property type="protein sequence ID" value="GIY49875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17840" checksum="68BF96E62733774F" modified="2024-11-27" version="1">MAEGKWSLIRGCPSIRPQSSLRAILRANAVKAEEEFFFRAFHRNIRHNASFAVIEKEKEIESCRTIFAWDAYVKRGAIDFAASNVLLLFLPHRITTSKTAIETTIPEVAEKFIVFLALRHLVLQLAILMGGIEGGGGAPVIGGVGLPYNIQRQSRNSLHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U174</accession>
    <name>A0AAV4U174_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_438051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012119">
        <property type="protein sequence ID" value="GIY51505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U174"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="91"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15435" checksum="F241CB96EF70E15C" modified="2024-11-27" version="1">MSFCSFKCVIQGDYTIVMRLSCSGFPSKLKLSLDYNSVTKTILSCRKGCPHGAINPTEYSKNQLHLKSIQDFLLDVADKANIRTTAKQVVLDVGCGPGMGTKELMLPLIQERLEKMFAFDVSPVMIEIANQKYSDKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4C4</accession>
    <name>A0AAV4U4C4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_770541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012260">
        <property type="protein sequence ID" value="GIY52599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4C4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10182" checksum="3EE4566B3ED07842" modified="2024-11-27" version="1">MIGGVGENPFLLLHQVGGVASVKGSEVTGVEPSRPPPSSPLPIPGSHSEKAASDRTSLLPPSDDDWGREDPISPLHQIGMINEQGLHRSEDTAELTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U560</accession>
    <name>A0AAV4U560_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012305">
        <property type="protein sequence ID" value="GIY52908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U560"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11760" checksum="D720D6A6EB356A98" modified="2024-11-27" version="1">MFQKNTHRKNPDYFSLSLFLFAQNHVHPKAKKKKNNRKKSSPKVFYAKQKTTESFASIILFVIFYNNLPTLCSIPKDFMNKASVLDRTVSLAEVVEKFLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6A2</accession>
    <name>A0AAV4U6A2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_625291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012348">
        <property type="protein sequence ID" value="GIY53306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14213" checksum="2343D5808FBC4785" modified="2024-11-27" version="1" fragment="single">MIGYASMNSELQEAKKENCSPGCCFTMDLRLAHSTSKSSATSKAEMNRRDAEDKELFSTLENTPSNLKQVAIDIETLVTELSKQKERKEETPESHLHNEREHRGTQTKHRLIPRTISRCYGCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAM6</accession>
    <name>A0AAV4UAM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_132351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012541">
        <property type="protein sequence ID" value="GIY54675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11324" checksum="A0D5794946BDC9F3" modified="2024-11-27" version="1">MRRIFFVVNNTHSTAVKTELQGQVDGWNTHKNNTFRARRGKSVPQIHRVLRAKTSAFTVRRDNPVASPARRSAQVGRVTTLWLRAFFVPGIARRRQGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB15</accession>
    <name>A0AAV4UB15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_131331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012588">
        <property type="protein sequence ID" value="GIY54989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7775" checksum="787A4CE31A73774F" modified="2024-11-27" version="1">MVVFTCRLHGRTVCSGQPKYSLKLSFSESILGVKIGALQSEVREYVSSLHSRQICGSRVLIADRSVDLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBD3</accession>
    <name>A0AAV4UBD3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_668451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012603">
        <property type="protein sequence ID" value="GIY55089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="13471" checksum="1844B29D3EC32C77" modified="2024-11-27" version="1">MRDARRARFSKSTTPARRHVMPSTHRGACAVLFREEIGAASVIQPTYDLSSSVQFSARFLALLPLSQTIFFKGALSSVAKRHFLAHFFRSISRLFISAFSFLFFYRLSFWNDLETRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEZ3</accession>
    <name>A0AAV4UEZ3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein SREK1IP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVEN_248406_1</name>
        <name evidence="9" type="ORF">CEXT_815151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Possible splicing regulator involved in the control of cellular survival.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012759">
        <property type="protein sequence ID" value="GIY56338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437:SF1">
        <property type="entry name" value="PROTEIN SREK1IP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437">
        <property type="entry name" value="SREK1IP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13917">
        <property type="entry name" value="zf-CCHC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="82"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY56338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21782" checksum="FF930CB8770DFBFB" modified="2024-11-27" version="1">MDHSLKDLMAKLTNQAADNIRPACKKCGYPGHFTYQCRNFLKINPDKDIVLDISSTSSESEEDFISPLTKLRGNVKICFINIKKKKKKMEGRKRKSKHSKSKKPHRSRSPHSDSDSEKDSVSRSKKHRKKKHSDSESEDNDSISRSKKDKKRKHTDSESEDSSSAKKHKKKHKKHKHHKTGHKKKRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHC9</accession>
    <name>A0AAV4UHC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_259871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012881">
        <property type="protein sequence ID" value="GIY57307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9780" checksum="F51713CB038B3A97" modified="2024-11-27" version="1">MRDTFIPPPEPNLSKLNGKSVRNQFPRDSRETPKAKNIRLLLKESRSFLSPTIHFQRYRRKTLNYRDGRSSAARYYRGTKMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPB1</accession>
    <name>A0AAV4UPB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_369931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013215">
        <property type="protein sequence ID" value="GIY59573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12767" checksum="E8123B36E4E9E846" modified="2024-11-27" version="1">MHDEYINRNLRINPSFTSPPPFDLKKADDCENRSFHRTQLGEFASENKYTSGRLLITSRKNDFMRGVKGHSLFFTAILEHHRIMRRHLNSIAVLLLFWKEVPDCQSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWK4</accession>
    <name>A0AAV4UWK4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_126662_1</name>
        <name evidence="1" type="ORF">CEXT_71491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013585">
        <property type="protein sequence ID" value="GIY62128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14910" checksum="DBB7ECA94414F809" modified="2024-11-27" version="1">MKCQLLTSYSVDSSSLLPSSNGSLGLIWKQRLADIEVEPSVPFNLLTPTAVLSNVTFNEDLKVKFIKHEVHPVLLRQLALEIINNISARALVIYTDGSKSDSGRTDSGIFMKTSTGEFRYHFKTRTTAQYSAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWZ7</accession>
    <name>A0AAV4UWZ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_552601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013600">
        <property type="protein sequence ID" value="GIY62258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="34" mass="4015" checksum="4037D1D111119C97" modified="2024-11-27" version="1" fragment="single">MGGIHTRTRNPLCKTPESSGVYARDMRQYMSFHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY64</accession>
    <name>A0AAV4UY64_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_510051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013644">
        <property type="protein sequence ID" value="GIY62645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY64"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14851" checksum="221B5C3D197BA152" modified="2024-11-27" version="1">MSILSLHSDFYNVTGATVSVSYYKQCKFVYRPSLYMNTDFCQQLRCLSHRRTTCTAPCYSSHDLFQLFTLFIKLKSASCMKSAAPQEVEAFAEAANELMTQLMMTMKCRPRDTKNCRFFLCQSKDGNPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYU4</accession>
    <name>A0AAV4UYU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_117811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013682">
        <property type="protein sequence ID" value="GIY62918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14664" checksum="11324DA11A8FE049" modified="2024-11-27" version="1">MFSSVDAWWKHSHNLFAREVSNSTANGYLAETIFLHGKPSFLLVIGAHSNILRYFSTRGLGGWLTGALPGQAHVLMVQSWLDAQEWLESMLNKNPACYPAHKISLKSITTVFRKLISLLVSLYPGKLFSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V037</accession>
    <name>A0AAV4V037_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_452851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013761">
        <property type="protein sequence ID" value="GIY63591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V037"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10946" checksum="460CE73BC319F322" modified="2024-11-27" version="1">MFPKCKCELTPVIAFPAPTLSHHQKLKNETALRYKLGLARTGLAQLLLKHDKLQTTSFPELRIYIYIPIHIAYIFLVVPWSNAKENAASEIERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3Z5</accession>
    <name>A0AAV4V3Z5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_280771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013874">
        <property type="protein sequence ID" value="GIY64414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11318" checksum="942C60047302D599" modified="2024-11-27" version="1">MFSLHGCLMMQRKTIAFSLSTVMTCLLLQVVFNVLVESFHAFVRVQPQTDEVRGVCGGRMMSLQPRPVIEAMFRSLDCPGTWTGTDTPGDIRPRRKEAATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAY9</accession>
    <name>A0AAV4VAY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_23417_1</name>
        <name evidence="1" type="ORF">CEXT_513241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014223">
        <property type="protein sequence ID" value="GIY67287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="272" mass="31172" checksum="C5C956CC339919CD" modified="2024-11-27" version="1">MSEAEKVHPEPIEKNRRIRGSLRTNVTKLIKKIDEELASVNPNADSLQESFIILIEREQKLGNLDDIIIFQSPDAEIETEMEISLEYSEQIIKYKSRVNRYLSESVQVEPVRNSSDVSTLRKLYDEIIIQIRCLESLKVDINSYGNLLLPILYKCIPNDLVLRFNRQNSEGEVTVTSLLSCIKKEIEARGKDTSERSYICEAIAERAGLKTGERKRNKCLMLYESVFGWTLRGRDGEFNERTVGKESTGLFIRSSNESEENLSQVIRAFVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFR5</accession>
    <name>A0AAV4VFR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ceramide transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cert1</name>
        <name evidence="4" type="ORF">CEXT_741831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014431">
        <property type="protein sequence ID" value="GIY68731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001881">
        <property type="term" value="P:receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13283">
        <property type="entry name" value="PH_GPBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000104">
        <property type="entry name" value="collagen type IV alpha-3-binding protein-like isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045188">
        <property type="entry name" value="Boi1/Boi2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902:SF27">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902">
        <property type="entry name" value="SESQUIPEDALIAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="271"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY68731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="350" mass="39975" checksum="9BB2A5BE355902D7" modified="2024-11-27" version="1" fragment="single">MCDDHSVTLSEDEEDIENGFTQPELHGTLSKWTNYIHGWQDRYIVLKDGTLAYYKSEDDTAYGCRGAISIFKAAIKPHEFDECRFDVSVHDCVWYLRADSPEERNRWVETLEAFKIDSAYGSENNLRRHGSAISVGSTSLSNASITSFKKARGLRVKLAEMETFKDILCRQVDTLQSYFDVCAEMLKDETHKDNDVHMDDIDEDYDESTGDISVTNEQKNESPVHRFKGHSTLVTKELLAQHGAHAVDFKGEAITFKATTSGILNTLSHCIELLSQREENWKRRLEKEVEKRKKLEDAYKHALSEAKSMRPIVLGGPDYEEGPHSMINEDEFFDAVDAALDKSEQQEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHF0</accession>
    <name>A0AAV4VHF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphonate ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_253761</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014552">
        <property type="protein sequence ID" value="GIY69566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052443">
        <property type="entry name" value="E3_ubiq-ligase_RNF220-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031824">
        <property type="entry name" value="RNF220_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13459">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13459:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15926">
        <property type="entry name" value="RNF220"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="E3 ubiquitin-protein ligase RNF220 middle" evidence="5">
        <location>
            <begin position="171"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase RNF220 middle" evidence="5">
        <location>
            <begin position="211"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="460"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY69566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="501" mass="56117" checksum="23ED905B0ABF1A91" modified="2024-11-27" version="1">MRDSVTLQINETLNYSEEASYIGPSAAKRLKCASESLNLDEVKATKSNGSNFEDSCVNENAHWPVDCATPVSNSTEIEESNSSTNCGDSEQLQCTKSREETDSDNSQDSVLSGCSTVINSASDVSQSAVSPSSAESNDPCEVQTVEASEESNVPRRTRSSSNKRTKGINLRCPICSLTIRSAELETHFKQEVDKLTQVSRKLRKLKTDDSGINTTFVQVKSNRENRLSAKIGQYTAKNRKEIQCPGCSLWLSGPGTKLNEHISHCMEEDNLDEYIVVDDDEEDNFEEYTIGDETRIRAVSLIPGGHNSLQGQTVRNQHSEDDDVDIDVDTIAHGQPHKDKENDENLEQLRKAVLLDPNVQPCVLESRKWSNNEVSQSDEAKESRYLFLHLSIKMFSFCNHSHNLESAESTNSEGFLTDHTVDLSDICSEIVSNKNDNTLSKEQSFERKIKDINNQNQQVKCLICMDFYTKPVVSTSCWHVYCEECWLMTLGVKKRLVHNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKS0</accession>
    <name>A0AAV4VKS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_814811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014737">
        <property type="protein sequence ID" value="GIY70942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12103" checksum="CC4F623AB3D2B25C" modified="2024-11-27" version="1">MSKKSNDKNSKNNNKTEEQESKLRESFFPKLASKTAPDNDDSDETDNKEKEREQMQSSIDAILKKSPMPHKSKKRVPRKKKTLHKGKSRKIEIKSDLRMTSKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VN69</accession>
    <name>A0AAV4VN69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_573181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014837">
        <property type="protein sequence ID" value="GIY71636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VN69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18314" checksum="E5BCE9A40EE55182" modified="2024-11-27" version="1">MEDNTYKHENNDTNSSKNFESETLEDPKPTVDDKKTNQFFPPGKIQIAHDPENKILAHFVGESGDHLPCASEDSSRLDTQTNETVSSTLEKEIDTLESCSQKYSTNLLMSFENSLEVDKSINKQDVRKAKENLLLQMAAWKIILELLETFLSKKCLSLKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNB5</accession>
    <name>A0AAV4VNB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_138401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014867">
        <property type="protein sequence ID" value="GIY71845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8632" checksum="247B3D35703A2EC7" modified="2024-11-27" version="1">MWIRVCVTAKQKVEDGKHLAIKLFSWLPFLEPRSAEITPFRIKILPECPPLGWNGGVRGSKDKNNGVYACNRISSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTC3</accession>
    <name>A0AAV4VTC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_482801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015100">
        <property type="protein sequence ID" value="GIY73562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="22044" checksum="78FC7BF620BDC3BC" modified="2024-11-27" version="1">MVRNKKKKSFPVNAATSNLKLSKNHPLLKCEQRAAVRVQIMTNCRLKEYRDQLRLMQPGSIEADELANSINISSQTFKKLARLTQLSAEDLPNSKEDYNKILLEAGIETEEYQKKHSLHDVIGIMAKVANTPDSHMDIDQPVKNPRTPDAEGFIPPSRHLTAQPNIEQETERPIEAKKKSIRCIRNNRIRKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4W7</accession>
    <name>A0AAV4W4W7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_291341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015593">
        <property type="protein sequence ID" value="GIY77244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4W7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10899" checksum="6C126E7004E881A5" modified="2024-11-27" version="1">MRISYSNHQIAGILISVFYPLLNRSHRFSMGLKSGDFAGQSSCNKVCECLSCTRIFSLIIFAVVILKNMGVNLILISQIWTETKHPIIQNAKKAGSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W995</accession>
    <name>A0AAV4W995_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015765">
        <property type="protein sequence ID" value="GIY78526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W995"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12483" checksum="82534FE2DC1064C9" modified="2024-11-27" version="1">MENLQCGSPNGKMVILLMVNGNSSSGWINGKRFPGLAEQLRLMRSQYKVEIEFFLPTFQQALTNGSSFTGCHGETAELCIHSTGGLQLRHNELSNRDEHRLVPKMVHLFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9K0</accession>
    <name>A0AAV4W9K0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine--fructose-6-phosphate aminotransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Gfpt2</name>
        <name evidence="4" type="ORF">CEXT_785091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015769">
        <property type="protein sequence ID" value="GIY78569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9K0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046349">
        <property type="term" value="P:amino sugar biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000002">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="233"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="365"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY78569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="479" mass="53085" checksum="DF81C662BA7A8BD6" modified="2024-11-27" version="1">MALSPAEKIADCWKLQFELNPNTSHSFTNNLIASETEKYFNSPHTNYIQNVTATEAWKSSFFVGIKSKTHLNTNYIPVLYSKDLEKQKKQDLRSAQLAPPLSSGTMPSQGIHRSGSTTEFHPVGEEKQVEYFFASDARAVIEHTNRVIFLEDDDVAAVKDGNLTIHRVKRSLDGSMSREIITLKDGYPEIMKGSYISFMQKEIFEQPESIINTMRGRVNLTEETVVLGGIKDYIPEIKRCRRLLLIGCGTSYHSAVATRQILEELTELPVMVELTGQCETADTLIALRYCKNRGALVVGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQFLSLVISKDRISTQLRRSEISRDVSSKVSVGHGYNHATCLEGALKIKELTYMHSEGILAGELKHGPLALVDDAMPVIMIVTKDPMYSKCMNALQQVTARGGRPLIICEKGDVETQKFAFKYLEISHSVDCLQGILILAVAVLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WB95</accession>
    <name>A0AAV4WB95_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rap-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_139082</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015845">
        <property type="protein sequence ID" value="GIY79099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WB95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11210:FF:000002">
        <property type="entry name" value="Signal-induced proliferation-associated 1-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050989">
        <property type="entry name" value="Rap1_Ran_GAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711:SF32">
        <property type="entry name" value="RAP GTPASE ACTIVATING PROTEIN 1, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711">
        <property type="entry name" value="RAP GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21022">
        <property type="entry name" value="Rap-GAP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="6">
        <location>
            <begin position="148"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="469"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY79099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="609" mass="68433" checksum="C12CD54FB7E6D788" modified="2024-11-27" version="1">MLSNPGPYPLIALPSGGGYWIDGIHHNYPTDCLGNPILPNYDFVPKIERDESAQLYRKFFYGKEHFNFIALDETWGPLVMSLKVDVVSSQEQLRVLIRTKEGLLQDVFHVNHASTSSLNPIQILKLMCEDIITEKFTPVLFPRASEMLLAYDEHVLVKTFKFGIIYQKFGQTTEEELFGNRTHSPAMEEFLDLLGNRIKLKDFKGFRGGLDAHYGQTGDDSVYTQYKDCEVMFHVSTLLPYTEGDSQQLQRKRHIGNDIVAIIFQDSNTPFLPSMIASHFLHSYIVVQAVDPLTPNVTYKVSVTARDGVPVFGPALPNPTVFRKNEEFREFLLTKLINAEIACYKAEKFSKLEKRTRISLLQSLYDELRIKTQEFCGIVGDSGKTEINGNSNRFLDSVRKAITSRVRSHSVETNLANSVMNKRSSSSTSNSSLSSIVAGEVSQNVPKVPKETLLKISSPNSVRREFRNRSLDSLNSGGTPLWVRTNSSPGTPISSPDTPPPPHFKPRPSESDSSSVNSLELEHIHNGSTDLTNDSTFSTSGEISSTNCSQCTENEAIIKQYEILKQELNKLKSDKLDLLKHNLACQREIKKLKEKEVKLTTDLSLASER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLU9</accession>
    <name>A0AAV4WLU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_299251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016306">
        <property type="protein sequence ID" value="GIY82921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16783" checksum="6D1A87CF91CBC621" modified="2024-11-27" version="1">MAIRRRPLLISQHCNIFRWQIPVTKAVISAKIPDAIIVYLLEEVLRKTSTNEVMKAEEDLEELLEEASSANDENKITHSLALKGLPREAELKHYMIHACRNKDKEITLLKFRQLQCENNLTVIYEMLWLVMQYLQSSPEKKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WT73</accession>
    <name>A0AAV4WT73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_283571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016663">
        <property type="protein sequence ID" value="GIY85528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WT73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9405" checksum="EFC508C17A23BDCB" modified="2024-11-27" version="1">MAAFRLGLSFQGEGRAIGKRRKKEFHHCSKSCLISTSAQLSAVAMGIGGRGEGREGGEGLNNFSRYFLVHDAPPPNDFWDYGTELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0K8</accession>
    <name>A0AAV4X0K8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC14-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Sec14l2_0</name>
        <name evidence="2" type="ORF">CEXT_668601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016966">
        <property type="protein sequence ID" value="GIY87710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0K8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="8"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="199" mass="22697" checksum="8B38FD224994147A" modified="2024-11-27" version="1">MDDRNYKPPEVLEKYVSTSYVCFDKDGSVVRYSDIGQTDIKALWKCVTKMEMLKFLMMQIEYDTDLLNLQRKGCNRPAVKWLPFTHALGSVMWCGVLGKPLMNIVYIFDYNHFSLAVATHLQTLQNLLFFLKNYVDNYPERLKCGMIINASIYYNLVFNVAKSILPATIIKAALLRHRGLEGSVARNGGRGSSAGLPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2M6</accession>
    <name>A0AAV4X2M6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017067">
        <property type="protein sequence ID" value="GIY88445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2M6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20086" checksum="73D2BFA8ABC0D058" modified="2024-11-27" version="1">MENSLIEQKMKFILLLRKAIGVSCDREGKKLSTENSLEEKAGLELGRCISGVPSMCGYPRITSNRMTRKKAKGVSRDSGGKKLSMKNSWREKAGLGSGRRISGIPSICGDSRITSNRMTRKNGFLKAEGVSRDRGENKLSMENSLEGKSWSWTYLRDFGFEMGLNFLKISQMDSTQIGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8A1</accession>
    <name>A0AAV4X8A1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_727271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017298">
        <property type="protein sequence ID" value="GIY90181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8A1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13046" checksum="2BDCE242B50057EA" modified="2024-11-27" version="1">MKGLRYDSSSNETLLAIFAACIFMEAKRYKMGLYGDDARPIKSAMHTRDIQDTHISRAIHLRIFLSTRTYPLKRNGKKRSQQELKTELQYHFFAQKKEVAPTFQKSIPPLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBZ1</accession>
    <name>A0AAV4XBZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_314111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017499">
        <property type="protein sequence ID" value="GIY92109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="11064" checksum="2122FC3CA4831A6D" modified="2024-11-27" version="1">MDKKFFESVVPKGNQKFEDSSSKLYRFIQDQITDESVSKECDDKEQKPVFVEEARRMCVYHLMASIQYIYTRYIFHKKTFYSWFKDSFVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XE30</accession>
    <name>A0AAV4XE30_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_517081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000202">
        <property type="protein sequence ID" value="GIY92859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XE30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="18747" checksum="1D943F1E8291AD7E" modified="2024-11-27" version="1">MHTFSIKSFSEICPECPWSRKLFPNIAAFVFTRKPNTPQKLKTRTTTRALKYFKSVPPSLPPLTILFNNDSLQEEFYYASFPLGAPELFKELISRGELPRATFEFTRKPNTPQKLKTWTTTRALKHFKRLPLLPPAAILFNDDSLQEEFYNELISTRGSRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFR3</accession>
    <name>A0AAV4XFR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_691271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017565">
        <property type="protein sequence ID" value="GIY92613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7533" checksum="807325CF022F2CD8" modified="2024-11-27" version="1">MFSLPFNCYCMASQDEAEDDECDRVYAIQLPSDFSSKNLLLFVPSWGRGVELSRGVLSFSNVQMTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ28</accession>
    <name>A0AAV4XJ28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_180571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000367">
        <property type="protein sequence ID" value="GIY94220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14778" checksum="A35A0C08CDC62811" modified="2024-11-27" version="1">MYSKFYYMFPIDKIKNTSDMKHLLHHLKHESSKHKIYDLHCIKENEKPHLITFAENLNHKYEVPSLLCSGILRGALRCPGRGSTWTPACCQIRTTSDHPETWKPGGTGCVKRCKIFERHTDSIAGKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLL3</accession>
    <name>A0AAV4XLL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_6761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000439">
        <property type="protein sequence ID" value="GIY94830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7679" checksum="41FC7A3B25D0AC21" modified="2024-11-27" version="1" fragment="single">CYFLQWCKDMLKQSAKSPSVAVLHSEVSVAQGHHVEVGSEVPQGCPPSNQLNRSGQPREVSCFFKNNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP24</accession>
    <name>A0AAV4XP24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_440141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017934">
        <property type="protein sequence ID" value="GIY95554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="28" mass="3042" checksum="AD5FC19AAC9A5E00" modified="2024-11-27" version="1" fragment="single">MDVGFAICWSDSTHTLLVTSADKTFAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVK5</accession>
    <name>A0AAV4XVK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_470431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018395">
        <property type="protein sequence ID" value="GIY99205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12590" checksum="F26F759992D5AA9B" modified="2024-11-27" version="1">MKEKGTSQALTSSKGVTVLEVTNNLLYDPYMKYQNRWRTSLKTDIPQSSRQQEYNSYLSGPRERSPNHQKLCTPSNRNLRMWRTSAHPSAMMGLCSGRSSFLIKDDSSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWV5</accession>
    <name>A0AAV4XWV5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018283">
        <property type="protein sequence ID" value="GIY98385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="19472" checksum="BCB48EB7BECEA276" modified="2024-11-27" version="1">MKGGPPSRREATRHRNLIAFSKDVRQTLPRRIKARKSINSASNSPPVAHKDFLGAKKNILRLLRLLKNFFRKFSAHYKGGPPSKREATRHQNLIAFFGRLFGRHFLAELKRGNPLPLRQTVARWRIRFSWYQENILSLLRFLIKVTIIIGKNYKLHNLSPLIPILEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXC1</accession>
    <name>A0AAV4XXC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_189731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000973">
        <property type="protein sequence ID" value="GIY98840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9258" checksum="977F676526E5FA69" modified="2024-11-27" version="1">MLHIKRKKPADMAQVKRRLVYGGFKLSRRLINKDRSHVFSPFQNIKNKRLGIIEPLQLDVSRSNKAKEHLFVRRFGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZB5</accession>
    <name>A0AAV4XZB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helitron_like_N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">EVAR_86116_1</name>
        <name evidence="1" type="ORF">CEXT_286731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018503">
        <property type="protein sequence ID" value="GIZ00105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9639" checksum="7C2096A1D53A350E" modified="2024-11-27" version="1">MSQPDCVVHQKVQLPEIETAPEPLHGLLIGAETNKNVSSKDYYAYRLMIRRGQDNVILRCRELCQQFMVDMYVKIESERLTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y040</accession>
    <name>A0AAV4Y040_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_333681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001067">
        <property type="protein sequence ID" value="GIY99586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y040"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12824" checksum="3E80B10F502BD18B" modified="2024-11-27" version="1">MQVIAANLDLMQVIPVLLDLDQMITVHLDLMQVIAANLDLMQVIPVLLDLMQVIIVHRDQVTTVQTIRIIIFERKFQYFRKFSRNPVYGQKRKNFQIAANFFLNVALPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0H7</accession>
    <name>A0AAV4Y0H7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transposase IS30-like HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_263734_1</name>
        <name evidence="3" type="ORF">CEXT_767541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001211">
        <property type="protein sequence ID" value="GIZ00822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0H7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase IS30-like HTH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ00822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11935" checksum="B6CC0165959FEE11" modified="2024-11-27" version="1">MDLKGKEITPEERKIIIKLRNEGKILREIGKIVGRTHSSIQRVINNYTSSKSIISKPRSGRPSKADCREKRYVFKSVSLNPLISAFQIANDEERDLKKHSMKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1X7</accession>
    <name>A0AAV4Y1X7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_693721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001128">
        <property type="protein sequence ID" value="GIZ00172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1X7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003654">
        <property type="entry name" value="OAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45882">
        <property type="entry name" value="PITUITARY HOMEOBOX HOMOLOG PTX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45882:SF3">
        <property type="entry name" value="PITUITARY HOMEOBOX HOMOLOG PTX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03826">
        <property type="entry name" value="OAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50803">
        <property type="entry name" value="OAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OAR" evidence="4">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ00172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10477" checksum="3BF11F222C4FCD4B" modified="2024-11-27" version="1">MGCFNASSPQGITSSSIMPSVSMPVNSLSNPAPPCPYATPTPPYVYREQCSTMTSSIATLRLKAKQHTAAGFGSYAPMSPRQTPTLSPCQYATVDRTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y357</accession>
    <name>A0AAV4Y357_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Centrosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Cep97</name>
        <name evidence="1" type="ORF">CEXT_497011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018736">
        <property type="protein sequence ID" value="GIZ01921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y357"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19108" checksum="87DD96745EFD9A07" modified="2024-11-27" version="1">MSAIPSADGDACYMQSSHLPNVHLAKNSMLLNKTNYVEYPNSSVENSPCSVNSEPYSFSKHHIYSNVVTNPPCQAKPEEFSKWKNSCISNGFVDVVQGKEHFPESLAGCCSKSCLSHQMKDKIITHHARCPKSGTQNLCKHVEKTDKSSESSESFFAGKGCAMLPKRQFAQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6E3</accession>
    <name>A0AAV4Y6E3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_86771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018815">
        <property type="protein sequence ID" value="GIZ02464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11808" checksum="90603FE33846F7EF" modified="2024-11-27" version="1">MDSSAGYCVKYVQFKDQAIPRSLHVCTSLLDPFCNAMTTSSTDVEAIDFLPLLDFTAKEPVSWSPLASIRPQPLPSPFHDRDFFKAAATHSHSCKRARGNVEINYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9I7</accession>
    <name>A0AAV4Y9I7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_605051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001548">
        <property type="protein sequence ID" value="GIZ03086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9I7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13427" checksum="5E4427CEFAB9177D" modified="2024-11-27" version="1">MVRLPAELVMIQMCFNNIYQIEKDFLYVFQKEHLSPSLLRRVIPSQKEPQLLSLGRWELKKFLPVEDARAVPSSGYSAKKREFGMMHGIIHSNWNGGKMRFNKRRRDFILERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M599</accession>
    <name>A0AAV4M599_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SHC SH2 domain-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Shcbp1</name>
        <name evidence="2" type="ORF">CEXT_473551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001875">
        <property type="protein sequence ID" value="GIX67405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M599"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007112">
        <property type="term" value="P:male meiosis cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057508">
        <property type="entry name" value="SHCBP-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045140">
        <property type="entry name" value="SHCBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14695:SF4">
        <property type="entry name" value="PROTEIN NESSUN DORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14695">
        <property type="entry name" value="SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23762">
        <property type="entry name" value="SHCBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHC SH2" evidence="1">
        <location>
            <begin position="32"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="228" mass="26217" checksum="F9CF6913F89DED28" modified="2024-11-27" version="1">MDTESDFSVSYSCPNVYRVELASMKDLAITFAEILEGVSFSGVEGSLVDYVTSVVEPIGWKAVWRSTKDTSPLDLEYDFIAEVTNVSLCGLEAEIHLKSVIIDDEISSSLDYLKEGLNIENPRNVPLRELYVVSEDDHEEFFQKTAIAIEHVRFYYKHICRPWDDEPDFVYTEEIIKTRVQLYFDMKNNIIPKTMISKIKSILKEGTRIAKELKQLYSDMGISDSKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M858</accession>
    <name>A0AAV4M858_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_195001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001917">
        <property type="protein sequence ID" value="GIX68010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M858"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12405" checksum="26FEF545829B5B4D" modified="2024-11-27" version="1">MSTLPRRKRCENGTTRCTSLYPNAALLLVKYPTVSLSPCSFPESHFLLPQPEISPALASPPSSQPENPRRLAVRRLIRTNLSLPGVPRPLSHLGGNKYWSLLRREEQERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MB18</accession>
    <name>A0AAV4MB18_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_582171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002072">
        <property type="protein sequence ID" value="GIX69667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MB18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043943675" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10800" checksum="B9015E7C9908BEF3" modified="2024-11-27" version="1">MFLGLRFICLIPYSSVYPLGYGNEKVVSRLTTARTLARLPQTPTSALYPHPSSGSEPRSGIMICPRDLTTVKKIPLFLWYHEAYENTKGAALSSTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCU8</accession>
    <name>A0AAV4MCU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Teneurin-m</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Ten-m_6</name>
        <name evidence="1" type="ORF">CEXT_59271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002101">
        <property type="protein sequence ID" value="GIX69992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18051" checksum="68E8EEB1382A58F2" modified="2024-11-27" version="1">MSRVAVVLVGQKDRPGFLYVMISVWVEAAMNDTQRYDKRRGKNEGTHIILTNSSLSDCCARECAMPFQKGRHPRVNYFCRLFVFPLERLASEEGFRATPGNKLLHYLEPGTWYFSVINDDSTSVGISFLPSLARDVPTSCPNNCHHHGNCHLGSATAFLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD91</accession>
    <name>A0AAV4MD91_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_687021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002134">
        <property type="protein sequence ID" value="GIX70389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD91"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8818" checksum="6123D882A9D59F10" modified="2024-11-27" version="1">MSTDESLTNIGGNNQRIVSDFQQNLSQPQINVDCVWSFPRSTKKSLFTQVLPVLADQFTPFALENAQGSSSNQTVILWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDC5</accession>
    <name>A0AAV4MDC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_557801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019655">
        <property type="protein sequence ID" value="GIX70172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8977" checksum="E10C8B545D2FE576" modified="2024-11-27" version="1" fragment="single">GVMLTNAFSHASLFFVDHWSSYRRTKQIKSLAPQSFQQSPTYIKLRAFAWLNLSRWGQLAELVLKLWEEHASLCQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHB4</accession>
    <name>A0AAV4MHB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_297121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019701">
        <property type="protein sequence ID" value="GIX70826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="14110" checksum="37F6D41DE0B1A4D7" modified="2024-11-27" version="1">MRLDCGSRKCFRVPCLRKKPNSIFHSESKSFICTPYAKLIKYRISDKSPIKRHVQIEFDTSSEMVARVDAHVQPSVSLDKAGTEQTRILRGLKRKTYYRKQRILFSRRAGDETPKKPRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQF5</accession>
    <name>A0AAV4MQF5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_419401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019975">
        <property type="protein sequence ID" value="GIX73691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQF5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19675" checksum="3B1DD754F1D9F0D3" modified="2024-11-27" version="1">MPLIDNSDWKLVEMRFLDNSVCHFAGLIECNCCLIGNGTPFDLIAYYFVSEDIEQEQKLVNVDIAGSDKAVVNGLVPSGKYQFKFQIDPPWRIRRDAKSFQHHIVASCSRCHLQKRGDVWQQNRDCVINIKIPIACTGSRFTIAGLSTGFYYEIRVRAHTKTGYEIPIETKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTN6</accession>
    <name>A0AAV4MTN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_407771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002569">
        <property type="protein sequence ID" value="GIX75215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10848" checksum="C7C42904048CFD5F" modified="2024-11-27" version="1">MFIHEKNEKGFEVISVVPSSSSHTICPTRFPQSLSETALVWFFPVSFDEPNNYVSHSPDDALRPGSDGPQVLVPLLDAELGLNDLLHEEAVALPFKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWL0</accession>
    <name>A0AAV4MWL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_7241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020276">
        <property type="protein sequence ID" value="GIX76673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11182" checksum="715D27AF213755E1" modified="2024-11-27" version="1">MAILVEKITTHQAKSTHPNLGDRRVKKAKITKEFPWVMEKNSIKVNTKKIEKEKRKMPYGGQPVGHQDLRICPGSMFSSMDICEYHMGSLLKALSLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZA5</accession>
    <name>A0AAV4MZA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_208421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020359">
        <property type="protein sequence ID" value="GIX77829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14695" checksum="9F8492A4675014B3" modified="2024-11-27" version="1">MGKKSNTKSKFAEAIDPRFTGLFKNSSSNENDSNHILENESDIQEGIQMFDQDLGFQDFLSKKLFEYLDRSIKEIEVEGPFQENHIIQHETGDISYLPTSDILSEVLPSTCVEPTIKPKKKKKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0L5</accession>
    <name>A0AAV4N0L5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Estradiol 17-beta-dehydrogenase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hsd17b2</name>
        <name evidence="3" type="ORF">CEXT_775491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002785">
        <property type="protein sequence ID" value="GIX77721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0L5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF36">
        <property type="entry name" value="D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX77721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="368" mass="41295" checksum="A38307B331D3424B" modified="2024-11-27" version="1">MHLIGRYALVGVTHFLCTGLALKVLSYILPCFLTCYYGCAAKFLMCAIVAQLTFGFTKKKFLSDKIQPDNKAVLITGCDCGFGHQLAKRLDKGGYHVFASCLNPNGPGADDLKKSCSKRLQIVEMDVTKDDSVKEAVNYVKDNLGTSELWAIVNNAGIQKGFITELTSIQDFKDTMEVNAFGPVRVTKGFLPLLRQSRGRVINIASLAGRISLPACAPYAMSKFACVAFSESLRYDLDVWGVRVISIEPEFFQTDMTKVENLRQRVDDTFASIDDDVREDYGKKFIEDFRARVNLMSASSKVYKVLNALELAISLEHPSLVYRPCRNCIVAVLYRIFEYSPKVMQLLMVKFYFYITGFPKPKEADNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3Q5</accession>
    <name>A0AAV4N3Q5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_544891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002862">
        <property type="protein sequence ID" value="GIX78711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3Q5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9030" checksum="F6EE0048C104602F" modified="2024-11-27" version="1">MQDFIILTTHAFNGVSGEISRQRFPVSKSLQSWSMFWMGDGPVTGRFMAHFKALDLGRYQTKFSVKICQDDTAKDYMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NC78</accession>
    <name>A0AAV4NC78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_516231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020660">
        <property type="protein sequence ID" value="GIX81266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NC78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11227" checksum="710EED9765B3D69A" modified="2024-11-27" version="1">MEGDNGPGPSVQWTPVGNEISGQEADLVVVVGNLNGNIGWMYRIVLQVVHTIVGRASNDAPEAALFAQPNDTDKDGRGGTMDPPLEMRFLVRRLIWLQWWAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFN0</accession>
    <name>A0AAV4NFN0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_615071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020797">
        <property type="protein sequence ID" value="GIX82653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9778" checksum="32EE1C244EB9AC38" modified="2024-11-27" version="1">MRVLFVKLDNIHVRYVHQKKKKMKLNYVCGRRKKKIAQVLRVLINGFGTGSKAAKTVDPITYISDYRRHNNEDECVTQGFPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLD8</accession>
    <name>A0AAV4NLD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_91870_1</name>
        <name evidence="2" type="ORF">CEXT_714761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021078">
        <property type="protein sequence ID" value="GIX85607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="257" mass="28854" checksum="A11967E34F29DC03" modified="2024-11-27" version="1">MMGWNDSSLWKYGCPLAGASGDILKLQVVILDGENVAYDAKLLSAINFNKDIAGDIHSMNGDDLRRFYCFLVFYCAFPYLSSNDLLATTSWKSKLICASCMWSSLSITADAVPNTEESAKCQLLCFPSNEKVVKGTQLLEDLNNVLELVKDNLRKGGSIDMGLIAKIRGIKETFNQLKMNPSDLSEELLENFKEKTFEAFRLILQGLNVDSMNSQQNSNPKQYEKISLRGTLKPWLSYKSEDNGEERDTTNKESLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM95</accession>
    <name>A0AAV4NM95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SH3 domain-binding protein 5 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pcs</name>
        <name evidence="4" type="ORF">CEXT_697791</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3BP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020956">
        <property type="protein sequence ID" value="GIX84372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007940">
        <property type="entry name" value="SH3BP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19423">
        <property type="entry name" value="SH3 DOMAIN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19423:SF1">
        <property type="entry name" value="SH3 DOMAIN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05276">
        <property type="entry name" value="SH3BP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="96"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX84372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21817" checksum="3C707F58D39663CA" modified="2024-11-27" version="1">MDESTEAVDPRVKDQLEFLNSYTDEINSLELQLDDANATFRNTLSEYSQRLKLIAKKLGKCVRIARPYYEAEESSQAAKLECEEAAIRYHRACGVHKEARETIAMAEKKFDSQKEDYEFDAAWQEMLNRETIKLMNAESLKKESEQEHKRTAQVFSAAVQKVKILEHQLKKEIIKSRPYFEQKKKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR47</accession>
    <name>A0AAV4NR47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_150971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021120">
        <property type="protein sequence ID" value="GIX86223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9342" checksum="31BC837086A4CEBB" modified="2024-11-27" version="1">MEPSKNRSPFIKKGLERNDEQIRLGNLTSSAPKKSSAAIRRATTQQINRWNGGRSDVFVFRQGRREGSSISSGSHHLPGTKTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3T1</accession>
    <name>A0AAV4P3T1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_755541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021522">
        <property type="protein sequence ID" value="GIX90693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3T1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10289" checksum="975A0A6D0E3CAF84" modified="2024-11-27" version="1">MEKNKKNKTKQNKIIIKNRSRSWGCSGRAEKNKWGQTKIYDPVLSPRMPGDATDRMLEVPTLPLDPLMWKAPCLFSQTMGSAETVPPCLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P633</accession>
    <name>A0AAV4P633_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_390511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004023">
        <property type="protein sequence ID" value="GIX91415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P633"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="58" mass="6696" checksum="254F4AFA9B8E1AF5" modified="2024-11-27" version="1" fragment="single">MRTFRCEKILSKNITVFIKSTNEYLISKRPVCMPKVLMLFLGRLGSPLHAEMPKNKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6S8</accession>
    <name>A0AAV4P6S8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_276801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004105">
        <property type="protein sequence ID" value="GIX92198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6S8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14505" checksum="9EF29D96E2C6FD4F" modified="2024-11-27" version="1">MKKSTKKKQDKKATLKNHILELRCSSLEKDAFNAAHFNTKQCILMKLSPPLRKGNKGERRWGGIIFELKRLCSDAWKLMGKKGSRRKKKTGKGEGEDSYLISRPKVPFNIKPDEGVTLYRRYSLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9N7</accession>
    <name>A0AAV4P9N7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynein heavy chain 3 AAA+ lid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_802921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004207">
        <property type="protein sequence ID" value="GIX93173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9N7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="24805" checksum="5FEA720801F00713" modified="2024-11-27" version="1">MGLRQEKVDYYPGRYQHATHQLLGRPAEDCFCTFFCLRLNRNKGQIMLFTQKVCEHQFPMQCPDMEMWPPAQIAQSCLGSGSDQKDRDMGSKANVKMKPTLYVGDILVAIEFRKVEFCFQKSKLNSFVHENSSVFFRNVFLISVNSNCCRADHHDADSAKFHYVFNLRELSRIWQGMTSTLPSIISDQALSSPVEARVLQGHLLTGSVHSWILIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBB7</accession>
    <name>A0AAV4PBB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_675771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004402">
        <property type="protein sequence ID" value="GIX94652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23215" checksum="11C2D8481EBA8513" modified="2024-11-27" version="1">MFHPCDLPTHYEAGADAVSKAWFHLLACRPTSINLKSGGYQGCCFCIVGCADKRTLILVCELLFKCGHDSLKIVINAHQLSRIGHIWNSSWEHQRALSHPLKTTAVYIFETLIGITDTTGHIWNSPRDHQYYRAYLELFYGSSTLQGIYGTLLGSTILQGIFGTLLGIINTTGHIWNSSREHNTAGYIWNSSRDHQYYRAYLKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PI28</accession>
    <name>A0AAV4PI28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_633581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004531">
        <property type="protein sequence ID" value="GIX95549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PI28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8809" checksum="BED5BBADE7FB33D1" modified="2024-11-27" version="1">MENDLMKPCIHWSRHTRAGGRSREGINGNKTVHRSKTQSNKEIIQWISMYKKWLDLEMEWKNVNHFEKRNIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PN13</accession>
    <name>A0AAV4PN13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_135911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004810">
        <property type="protein sequence ID" value="GIX97688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PN13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="48" mass="5820" checksum="8D368234BFB31DF6" modified="2024-11-27" version="1" fragment="single">SLRMNRDGEVLPSEEKIFLEQKERQNVFDWDGGWKEKRDQTIREVDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPL1</accession>
    <name>A0AAV4PPL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_355871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005031">
        <property type="protein sequence ID" value="GIX99337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16524" checksum="73EF628F46BFF141" modified="2024-11-27" version="1">MFAEEDLAQTELWQGNFTYAIPIPFNSLSKAFARFVTHVSAFLGLFPVTLSFFCPDKSRASSLSEWKTFVPYTCKKGPTEVPTAFPPLFFRNIFARRKKNSPRGLFFYKYSQTLFSKEEPRYGGDFRLIFDQNVGFERVKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPT5</accession>
    <name>A0AAV4PPT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_240961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005073">
        <property type="protein sequence ID" value="GIX99632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9126" checksum="91FC1DEAEA765143" modified="2024-11-27" version="1">MTETMVDTFSDETCRPQDICIELLLASPDNLQDMINHFDESHLDFSMQISYCWCGKISITSNHGHQKNLDSINFVSTSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSZ1</accession>
    <name>A0AAV4PSZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_603511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005157">
        <property type="protein sequence ID" value="GIY00240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7908" checksum="EE476D43B7A3A579" modified="2024-11-27" version="1">MVHECISVGMDWGLRDETERVLPVPCDVLGERRRCFSAVRSPVGPPIETAELAPDARLDEGRWRFCAHTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUW4</accession>
    <name>A0AAV4PUW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_202961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005237">
        <property type="protein sequence ID" value="GIY00900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12034" checksum="78F1A521ED4F0E27" modified="2024-11-27" version="1">MGGFLFPQEVIRHTLFSQVKGELSVPAIPVLGRLNEVYTLSSGFGSVGCYGDGQQSELQGPDNEPWGANNAPLGLIKGQAAFTLVQSRETTNTGVKVSWTIYMDIRVFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PYH2</accession>
    <name>A0AAV4PYH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_606031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005242">
        <property type="protein sequence ID" value="GIY00962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PYH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13848" checksum="1935E5988F18CBAE" modified="2024-11-27" version="1">MSKRQKRTSMQMYQLLSINHLKVNRLQKSVDTLPYIPTLLADIYVEKEKLTTFQQRQLPFPHWNRCRVNPISSRVRFPGCETCCWVTKDGITSKGDSTELQGRSELPVTAKVSFTCRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q264</accession>
    <name>A0AAV4Q264_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bestrophin homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BEST1</name>
        <name evidence="8" type="ORF">CEXT_648001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Forms chloride channels.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005468">
        <property type="protein sequence ID" value="GIY02631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q264"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034707">
        <property type="term" value="C:chloride channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000615">
        <property type="entry name" value="Bestrophin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021134">
        <property type="entry name" value="Bestrophin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10736">
        <property type="entry name" value="BESTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10736:SF65">
        <property type="entry name" value="BESTROPHIN 1, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01062">
        <property type="entry name" value="Bestrophin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0868">Chloride</keyword>
    <keyword evidence="6" id="KW-0869">Chloride channel</keyword>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="228"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="325"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY02631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="369" mass="41810" checksum="E1607474E54A3996" modified="2024-11-27" version="1">MGWLKVAETLVNPFGEDDDDFEVNWVIDRDIQVSYLIVDEMHQEHPELIKDQYWDEINGIPCETTNNRSLLSNHLSGSAFSGISKLGRSFHPMSYERKGIINMMQDFLSRESSVRKKSCGRLHPKIARLIHLHPVRLLVLRHQKSIKIVVDSMMISFIYQIYPLLIHVALVHKVLVIIAICQWKTYFGREDIKGPTDISKFEAVFFVLAKYRSSQKSLIGSVHGRSKLTMKTDNNKDTDSIAPDKRDDNRDDENSLTNSDEEVTVRESYQDPQDMSKSTTDIGKLGKDSSTSTLVPIDGSLEGTPPAENRQSGYESDSSKKSVFIETSSKENFQSNSTIDMNMDNTLNDNIKSNPCLSKPSSIIPQKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2X3</accession>
    <name>A0AAV4Q2X3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Uridine kinase</fullName>
            <ecNumber evidence="17">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CEXT_254413</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="15">May contribute to UTP accumulation needed for blast transformation and proliferation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 17">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 17">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="17">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with RNF19B.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="17"/>
    <dbReference type="EMBL" id="BPLR01005570">
        <property type="protein sequence ID" value="GIY03370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2X3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000010">
        <property type="entry name" value="Uridine-cytidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000200">
        <property type="entry name" value="Uridine-cytidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="19">
        <location>
            <begin position="87"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="20">
        <location>
            <begin position="315"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00056790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00065923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="GIY03370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="533" mass="60504" checksum="D3A8380C572B8CFB" modified="2024-11-27" version="1">MRVFGSGDELNFEDVPADDEMQSSPLSPGFSPLASPSHRVKKRERTWSSSKSAVLREPVLRTRQRTIYTAGRPPWYDTHGQLVEPFVIGICGGSASGKTTVARKVIEALDVPWVTLLSMDSFYKVLDETEHRKAKQNNYNFDHPDAFDFDLLIETLRKLKEGKSVDVPIYNFVSHSREKRMKTMYGANVIIFEGILIFAHKQLIEMMDMKVYIETDSDIRLARRLRRDIMERGRDLEGVLKQYEKFVKPAFDYYIAPTVVHADLIVPRGGENEIAISLIVQHVHTQLQLRGLKLRTKLAQCHTNQPLPEALVILPSTSQIKGLYTFIRDKNTSRDEFIFYSKRLMRLLIEFSLSLLPFKAITIETPQGIPYQGKRIATEKICGVSILRAGETMEQALCDVLKDVRLGKILIQTNQDTGEPELYYLRLPKDIKDYFIILMDATVATGAAAMMAIRVLLDHDVPEENIMLCSLLMAESGVHTIAYAFPKVKIVTSEVDPEVNDSFRHINSVRQWANGSIIFGEAVQAKACMNQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3R3</accession>
    <name>A0AAV4Q3R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_8191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005644">
        <property type="protein sequence ID" value="GIY03964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="62" mass="7230" checksum="7C24BDBC682B1325" modified="2024-11-27" version="1" fragment="single">MRKLNQYDNAFKTSLLTTFHVVKFAFRKQFLIKKKRNCPGTGNAVVKLKGTYKQVQPSHNRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4U4</accession>
    <name>A0AAV4Q4U4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_642021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005701">
        <property type="protein sequence ID" value="GIY04354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="221" mass="25783" checksum="FC7C560F12B1A60E" modified="2024-11-27" version="1">MHGLLNNKTVVLEPNTASPSTHKGEMHSKLNFSDVEMVLHGTACKCFTVAVFLNDLFCGEVRHDLYTSSNNPTYSTAILKKKNRRFLKNVKKEKSLEQQQMKFNSFREKRTLVNLTWRKTLVQTPPQTNTSFTQTNPIPKCHPSPLFSFRGDQWREKEEWFWEERRRKMHDLLKNKAVVLEPNTVDLQRIRRKCIVYTTYPSFLQHLSNPPPPPAPNSIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QEC7</accession>
    <name>A0AAV4QEC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoinositide 3-kinase regulatory subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Pik3r4</name>
        <name evidence="3" type="ORF">CEXT_690051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005981">
        <property type="protein sequence ID" value="GIY06612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QEC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY06612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="30164" checksum="03D01C5E65CC946C" modified="2024-11-27" version="1">MITDKAGILIRQYVKDNLYDRISTRPFLNSIEKCWIAFQLLQCLSQCHELGVYHGDIKLENIMITSWNWVLLTDFASFKPTNLAVDNPADFSYFFDTSRRRTCCIAPERFIKTMTSSNFYSAGTATVSSSSSSSVAPSSPSLIIHADEIKTGDLTEAMDIFSLGLFTEGTCPFDFSQLLKFITGDFDPHETIQKIEDSNVKKLIQSMMQKDPAARLSASEYLELQHDKAFPEYFYTFLNGYMKSYVSVPESPDEKIYRLKKTLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMB6</accession>
    <name>A0AAV4QMB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_19619_1</name>
        <name evidence="1" type="ORF">CEXT_294081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006508">
        <property type="protein sequence ID" value="GIY10330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="19797" checksum="9341ABB0702F05FA" modified="2024-11-27" version="1">MISQLEDAFQQSVDPIAEAIYFSTLVLASQKHKGIRQDKIDMCSEYALRTPPMPSHPKYRDRVFCLCAKNGHVELRAQSAGRLRSVVQPRVELAADGADGQLLGAHGIPLHDIGRHRKIQRNFVIYTAAELVQIKRNVSRDMTTLEKAVNNYVPVLNPASREVGKKTSGQSWTDAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QV83</accession>
    <name>A0AAV4QV83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_769501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007024">
        <property type="protein sequence ID" value="GIY13958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QV83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10498" checksum="2E5F153E83DE4B0C" modified="2024-11-27" version="1">MPVCSTTKPSRAVSEIARWFALPRAPTAQNEITLLEKVVGGGGGVCVHEVIMHPEYYTRKGIKFCQSVVEHLYIRKLVSATKNRCLKLLGRATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZA4</accession>
    <name>A0AAV4QZA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Probable uridine nucleosidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">URH2</name>
        <name evidence="3" type="ORF">CEXT_488351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006946">
        <property type="protein sequence ID" value="GIY13457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052775">
        <property type="entry name" value="IUN_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190:SF1">
        <property type="entry name" value="SI:CH211-201H21.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190">
        <property type="entry name" value="SI:CH211-201H21.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY13457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="359" mass="39476" checksum="392E7DD75B06BDE8" modified="2024-11-27" version="1">MAYSVLRRKRVLTRRMINLILNVLFQCARHIIQMSDKEDTRHLLIIDTDCGSDDAMAIMTALGPSGRRTHRLLAITCCFGNTTLDHVCLNVFRVLHVCQETGVLVYRGSSAPLLTDKVRPEIVHGSDGFGDCGHLFPTGEGVLEDTPAPAALVALSKKHPSITLVVLGPLTNVALAHRLDPEFTGRLSKIVILGGNYKGVGNTTETAEFNFYCDPEAANIVLTESQCPVHIVPWETVLEYGIDWEEFEAMLAPPTPKARLLKSATAIVTEVCHKEGYCQFLDCDVLATVAALRPDCVTTSLRRSASVECDGTLTRGMVVCRKHVPGETEVNIAVNFDESILNNLRKEMVMESTPEDWSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZH4</accession>
    <name>A0AAV4QZH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_688551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007128">
        <property type="protein sequence ID" value="GIY14665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14003" checksum="7508CBCEFE340840" modified="2024-11-27" version="1">MACRDGIPVVIAEIYLGELLFPICWLSSFVCEYTGRNCVVKLGKDIQEMQVMSVGNPDYNLNWQTYKSRSVDFVRRITMRAEIKLIRPLHVMSDSRPIGFACINCGPDKGIPIMSSAKFSTVFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6H3</accession>
    <name>A0AAV4R6H3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor Adf-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_01379</name>
        <name evidence="2" type="ORF">CEXT_528081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007450">
        <property type="protein sequence ID" value="GIY17002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6H3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006578">
        <property type="entry name" value="MADF-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039353">
        <property type="entry name" value="TF_Adf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12243">
        <property type="entry name" value="MADF DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12243:SF69">
        <property type="entry name" value="SI:CH73-59F11.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10545">
        <property type="entry name" value="MADF_DNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00595">
        <property type="entry name" value="MADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51029">
        <property type="entry name" value="MADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MADF" evidence="1">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10890" checksum="379EF1F56C261F2A" modified="2024-11-27" version="1">MDKFIKAVKNNPCLWDMGHPAYKDFEVMDKCWVKVAAIANFPDAKAAKIQWKKLRDNFREALKRKKNPRTTLGHGDINAKWNSSSLLCKVKIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9M8</accession>
    <name>A0AAV4R9M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_138771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007420">
        <property type="protein sequence ID" value="GIY16842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8969" checksum="A14144AEC8BACF67" modified="2024-11-27" version="1">MFCLESQHLIAAQSPKIPKQSCSIRTNLDGYRSRELFCFFENSRGNSKRFDDLRCKFCIQAPPPPSSTKRKIFPNTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9X1</accession>
    <name>A0AAV4R9X1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_82651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007464">
        <property type="protein sequence ID" value="GIY17096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9X1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14599" checksum="4ED7EB007E04207C" modified="2024-11-27" version="1">MAHTAEMAHSADSSLGRDGSFGRDRSSGRDSSFGRDSAFGRDSSFGRDSSFGRDRSSGRDSSFGRDSSFGRDCSFDKFSNLTNPARPKARGVFRPSSRQQSRLKIVPLKFSCHRTISIFFITVDPVVEMRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDI0</accession>
    <name>A0AAV4RDI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_569541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007868">
        <property type="protein sequence ID" value="GIY20348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8379" checksum="9CAC8905E418AFAB" modified="2024-11-27" version="1">MPSAPLCTRALYMALSSASFGITKSLRLKNQNFVQPELHEEMKGNTWEFSGKEERMGVKNKCALDWRSEDRGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4REJ7</accession>
    <name>A0AAV4REJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_263211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007637">
        <property type="protein sequence ID" value="GIY18522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4REJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12679" checksum="187FC6568BCC04B7" modified="2024-11-27" version="1">MSSGLKAFTLSLCDSGGLADVDLQKHVLSRFRFTALLSLLYWNIRLKMHKTTSVPKLHLSIFKRNVIVVSAVAYADVHHHKVPGACIYIAHRGVVAQSSGARITRQEPKEDILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLZ2</accession>
    <name>A0AAV4RLZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclin-dependent kinase 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CDK9</name>
        <name evidence="8" type="ORF">CEXT_1451</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008069">
        <property type="protein sequence ID" value="GIY21931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF233">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY21931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="274" mass="31295" checksum="E40BED09A626691C" modified="2024-11-27" version="1">MRASNVGTPITNHLIYGCFSLKKCPKLSRVVSGPFLSGERNRGGWHPENLKCPDVSNYRIISKIGQGSYGFTALREIKILQHLKQENVVNLIEICFSKVACLRFPKTTFYLVLDFCEYDLGRLIYNPKISFTLEDIKTIMKQLLNSLYFIHSSKILHRSPELLLGETNYGPPIDIWAAGCTMAEIFLKNPVMQVIIKEQRAIDLMDRMLCMDPHKRIDSDAALNHDFFWSDPMPNNDLSKTLSSTMSRTESKKVKICEVSRVYSSSYRGSRSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMA6</accession>
    <name>A0AAV4RMA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SOCS box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_123340_1</name>
        <name evidence="2" type="ORF">CEXT_351491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008115">
        <property type="protein sequence ID" value="GIY22199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03587">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001496">
        <property type="entry name" value="SOCS_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036036">
        <property type="entry name" value="SOCS_box-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07525">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00969">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158235">
        <property type="entry name" value="SOCS box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50225">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SOCS box" evidence="1">
        <location>
            <begin position="343"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="390" mass="46252" checksum="7CA2871413EB487C" modified="2024-11-27" version="1">MEILFSDEIQYRIIELRTAWEVALHSSLVHSSLDYLDFNTQTFTQEGFRKFHNNRREILYRFHLDLPKGLETNLKKEFIRDLPKCYASMSNENALHLEAFYVEYDLYSINLALDVVRTIESAVDKVDMVRRYTEIFQIHFSDVMDDDNQCLVTYMYDRILLLLYKSNCTDSDLVVDFIHSLDFHQWFLERENPILLRYVLKHMQIKRHDIRDYSPMAPVFHCFQNSFYGNVRPLLEYGIDPDFDIDDITEYGVLKTKLMAVLGIRMISERRAYLLSIFCLVYRNRTRDGIHEAHTVFWRTIPDHYPTSPEIYMIFRGAFRQSRLIRMGEMAASLSDEGTEHILSKGTPRSLRHLSRTAVRGCLNRSYQLPGGIWHLGIPKYLKHYLNLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RND2</accession>
    <name>A0AAV4RND2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein Wnt</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">WNT7B</name>
        <name evidence="11" type="ORF">CEXT_16531</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Ligand for members of the frizzled family of seven transmembrane receptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
            <location evidence="1 10">Extracellular space</location>
            <location evidence="1 10">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Wnt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008222">
        <property type="protein sequence ID" value="GIY22960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RND2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005109">
        <property type="term" value="F:frizzled binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007517">
        <property type="term" value="P:muscle organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046330">
        <property type="term" value="P:positive regulation of JNK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19339">
        <property type="entry name" value="Wnt_Wnt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2460.20:FF:000001">
        <property type="entry name" value="Wnt homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005817">
        <property type="entry name" value="Wnt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043158">
        <property type="entry name" value="Wnt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018161">
        <property type="entry name" value="Wnt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027:SF112">
        <property type="entry name" value="PROTEIN WNT-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027">
        <property type="entry name" value="WNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00110">
        <property type="entry name" value="wnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01349">
        <property type="entry name" value="WNTPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00097">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00246">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0879">Wnt signaling pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY22960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="325" mass="36948" checksum="A2692E6CCDF3D76A" modified="2024-11-27" version="1">MHSVWRVTKKKRDCFPTLVQMLVALRERTTYRGPLSEGTRLGVAECQRQFRYHRWNCSSIGSNQVFGHVVVVGSREAAYVYSITSAGVTFVITQSCSRGNVSDCGCDKSQNGQKALHHGDWKWGGCSVNVKYGIRLSRKFIDAREIEGDARSLMNLHNNQAGRKAVKHNLKTECKCHGVSGSCTMKTCWKTLPPFGQIGDYLMKAYRLSKKVIPHWGPTTSRSPIHLKLKKTKRQNRKPRPRDLVYLANSPNYCEIDPAHGSLGTVGRECNRTSSDIDGCDLLCCGRGYNTHQYMRTWQCNCKFHWCCYVNCDVCKERTENYVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPU8</accession>
    <name>A0AAV4RPU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_669321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008307">
        <property type="protein sequence ID" value="GIY23745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15393" checksum="51D4092D0251853C" modified="2024-11-27" version="1">MTNPLDNPEYCFGVSNEMCEIFLHFNGDDVDDIGCYECLPHLSEANIKLNEFSKLDMVIDKEDLSFGTSIPHCPPSHPHCHPSSSRSSSLVLTPSSPPFFINKKVSDLQNLWIVLVIEPGVFYLVSLVEFRANTSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSP7</accession>
    <name>A0AAV4RSP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_472571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008444">
        <property type="protein sequence ID" value="GIY24750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11704" checksum="FE2984F34A77E10B" modified="2024-11-27" version="1">MFWNIPASAKKEEIYILFFWRYFNRTFNSSAIFSFLSGIRKNLKTLTSEGECFRVTPSLGKKKKNIKSTKENKKKKEKERKSETGNGTTVSLAGGIFFAGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S086</accession>
    <name>A0AAV4S086_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_457511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008884">
        <property type="protein sequence ID" value="GIY27953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S086"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13834" checksum="7452B4163B907F24" modified="2024-11-27" version="1">MDLIQPLQKSAHVIPLNKKYSNSSAETISLLKRPDVYMQYAQSSKTNYSDVVKINTKAPNIEEIVNQRVESIVQNITIKMEQQTTLLIEIFQKTIENLVQYLVTVFHQTDLKKSPNRKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAU7</accession>
    <name>A0AAV4SAU7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_60232_1</name>
        <name evidence="4" type="ORF">CEXT_284511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009125">
        <property type="protein sequence ID" value="GIY29771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY29771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="42290" checksum="150C389C379078DE" modified="2024-11-27" version="1">MFTKALFPTFINYSVKTLQFNSLGLNCIKVNGVPNIDIVRYAARKGTRAAAVAKKRARKLADQNKPQPIPKYLQRKIKVNSELERKRCIDENWLDSQPIDNVFNMKLYRGKPYPFAEAIQMHRDAHVPAMLNDPSALVYANIELELKLKKKDRYIEELNGILNFPHEFQTFKKNRIVVICKSPEDQLLATDAGASYAGSATLVKQILAGSISKEDFDFLVCHPDMLKEVNTLRGILGRKFPNTSNKLLRIDIAEAVKGFMNGVEYNLKHSNSELDFGWVDVPFGRLDMPIEQLEENLKTVLNHVEKQKPPNTQNLLFIIRSLLFCERSKEKFKIAHWEYLPNYPINGIIREEVDEEEPKQEIASTQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SF54</accession>
    <name>A0AAV4SF54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_433001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009360">
        <property type="protein sequence ID" value="GIY31346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SF54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7455" checksum="03353B29369AA32B" modified="2024-11-27" version="1">MLQRNCQTALAGSGRAYESHVYSDVLHKLGCWPGSSPLLHKTDGWRLQDLDEKNEEKFLPRTLGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKY0</accession>
    <name>A0AAV4SKY0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alpha-latrotoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CEXT_536251</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="14">Homotetramer in membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cationic peptide 01 (latrotoxin) family. 03 (alpha-latrotoxin) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009646">
        <property type="protein sequence ID" value="GIY33491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="12" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="620"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="687"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="753"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="786"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="819"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY33491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="895" mass="101703" checksum="E26A62CBA2BF3333" modified="2024-11-27" version="1">MATVMEEYLTNLLGKSEDELVTEFCACNEEGKERIYLTILFALQKVILQSDTDILKKISLIFNIFKNEISEGLLLKFYENINNPFKITNPVILCCKQGNVEIIKLLFEEHGAFCNLLPKNSNEFNINPTDVDEDCHNAFYYAMRSGKTELLQYLINSWPGISEQDLDKILSDAYNELRLRNVAVPIEMHVVIRYHLIKQRFFNQTGDKSRVSVRMNDFHTFVEERINVLLEDIKELAKLSNVDEVFLTQSKIHNCALSADAEENEGKLTITRALQVIGEHIKNTLETPKLSDATGKLLLYSLPISTRDVIVDLRNALSHAESLAKRSELKQNNEYFFSKIQNDFIKLHSLVSEILCKIKTRVIVALLNKIFECTSIEDMKETISCFNLIEANEAFSRSPVSEELEQLENFMQDLRVAFNAIYRVLTKLKDSKNNETDIEFIKNNVDQSLLTVNMMTAKLDQSRIQEVGSLLKCILINVGPRMSWEDLDEVTGIAMKVFYIPEYELFDRQPQFLENNPPTLIGKNLRNHLAHFNAVNDVLEVDVFLDTILNAWKLVAEVTMAQSEKIDKVVQNVHLKETFQHHLDKIIKQKELYSALVKGDNSTITNCLRTGADLHGRDLNLWTALHFASKGPCLEVVKYVLSKNIDIGAKDVSGMNSLHVASYFGRADIVEFFLKDQNMSPNEETSDGMTPLDLAIGHDHKNVVETLLKNNASIQLKRGSHAPMRYAIWYNRKDIVEIILGKEWNIDASVTMGGFTSLHIAAERGHTDLVNFLLTKNANVRSKSDERYEPLHLASMNGEADIVRSLLSKGADSNAETLDGRTPLSFAAEMGRTTISELLVEHKANVNVADKTTQYSPLILSVKTGNLAMVKFCWGIKHVSMHKTSWDRLLYILQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2W6</accession>
    <name>A0AAV4T2W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167223_1</name>
        <name evidence="1" type="ORF">CEXT_80031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010390">
        <property type="protein sequence ID" value="GIY39027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="30708" checksum="4760DCCF740E7194" modified="2024-11-27" version="1">MCLSSANCFKIFPVVAHLLFRCPKLTSVGLLDTSMAITQLLNCLPNPPARFALRSCFWGISHRFHVEDDKEDYSAAYKTRFPKLIQTSVAMCPFVEKLVMEVIHIDSLKFLPYLSNLTFLNLNFKFCDSFCLPEIITLLSKVGHKLKYLLIEKPLEDFHLRFPVNVICKHCDNLETFGVFGNSVVEGKQVDYPSLKKLKKLSILNSDKDSLYYMLKNCVNLEELSLFFAFYLDDYLLGKFWLRTLCRSSSCSRYTSAISAELAWRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5E0</accession>
    <name>A0AAV4T5E0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_735421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010622">
        <property type="protein sequence ID" value="GIY40496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5E0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11112" checksum="72CA7FCF48F43E55" modified="2024-11-27" version="1">MTIHHKSDVIFKRKTMSSPNQEVYQVSSAGKGVRGRGTRVAHLLVVFLGQRLGQRDKAAKRLPMTYIHQQRRMLVYSRDLQTIDLKTSMKSAWVAGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TAG8</accession>
    <name>A0AAV4TAG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_709911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010680">
        <property type="protein sequence ID" value="GIY40953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TAG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="524" mass="60669" checksum="383B8C84C9377E9D" modified="2024-11-27" version="1">MDQKNSQQTEKQLSEIRNPGNHGEKQISHQQFHEEETNDGLDVSRRNHLFERENILLNRIFHVLDKYEELMEMQKKHLVLLDFLVRDLSQNILGSCDLSDSSKTVNRTDSSTRLDDSDSSSSMHKSDSFSISPTGSWKNLYHNRGTEDCEVQQIAKNCEPPKPIAHYEPEKYEGNYPTANIQQPSKDNELQQHSEDNYSLTVNPSSSWNKMWIVNSTLECKEQRDAKVYKSVKFMEDRGPRKFTEEYPEGYSQQHTRCKKSQNLEHSVQELHSVKYERYLQSGNDARSLHSKNNVCPLSSKKYAQLSNSERHRSSETLPNKANMLMYDPNLHSENNRGDLRSKNYGLDKPSGSYNRDHPTENYGLHLSSGNYDRHLPSGTYDRYLPSGTYDRDLPPGSYDRDLPSGSYERDLPSGSYDRDLHGKYDRDFPSGNYDGHLPSGNYDGHRPSGKYHRRPDSKKNDCQSNSENCGQNSENFARNMLSVNYDQHLLSQNKQPKRLPKNGFLKSVETNIWSPIRKYFDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TAT6</accession>
    <name>A0AAV4TAT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">E3 ubiquitin-protein ligase HERC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HERC2_1</name>
        <name evidence="1" type="ORF">CEXT_386961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010835">
        <property type="protein sequence ID" value="GIY42324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TAT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19211" checksum="B57280789C3DE27E" modified="2024-11-27" version="1">MGLYADNVPKPAINSLSGLLRSILNTVYGDTQIVKNSTNWLALEQHKEWASLSFMRAIACSSAMCQALSTPSWINLLIKIIGSSQLLTGGQLITKNTLIKGKWEMRPKVSLTASHCSTLAEEYVSVIRHLHSLQPWKTYISQFIAEYLQLLIDTFSQPLNLCDKLSLKNTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCW4</accession>
    <name>A0AAV4TCW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_54171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011151">
        <property type="protein sequence ID" value="GIY44498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12319" checksum="C6789CB90259901D" modified="2024-11-27" version="1">MVFILKGNISTPSPIDYEPIADFQNKDLSILKNNPKKKMVQIPIPDVKKSIYCDVYYTNSNRSYILSLIFRHQIFSSILTLSHPGLSSTRKLVKKRFIYKRLPIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TG04</accession>
    <name>A0AAV4TG04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactadherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Mfge8</name>
        <name evidence="3" type="ORF">CEXT_267112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011234">
        <property type="protein sequence ID" value="GIY45094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TG04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00057">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000016">
        <property type="entry name" value="Contactin-associated protein-like 4 isoform 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24543:SF334">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24543">
        <property type="entry name" value="MULTICOPPER OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00231">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01285">
        <property type="entry name" value="FA58C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01286">
        <property type="entry name" value="FA58C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043674638" evidence="1">
        <location>
            <begin position="21"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="168"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY45094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="512" mass="58667" checksum="10D7E468B32529C1" modified="2024-11-27" version="1">MLKTLLWIIAQCSLSSLSFGSVTGCSSPLGLMTGAVQDWQISVSSMADHRKDPGCHMRYARIYQPPGRAWCAGRKAAMEWIQVDLGVSAIITGLMTQGRGDGHQWVTSYLLSYSLDAYHWKYCSDVYGNRKIFKGNIDSHSTQTGYLDQNVTARFLRLHILQWHQHPSMRIEVLGCQECNSVISVPPQAQLTASSSRPWSKQGTCTPEDAHIYSFGGWCAKTNDMRQWLQIDLGPPTRVTGVVTKGRGDSRRKQWVTSFALSYSNSTNHWHYYKDDNLVSPKEFGGNMDKNTERRHYFNQPFTARYVRVHPMTWRGRVSMRLGLIGCQLKGECGQGFFRVHTDSECVENLAYKKDTWVNDKRHSWTGWKDGHSSYAVDGDEDTHLRRCAILDNYYVDYPVWMVDLGHRKSVRGVVITTWQGRGEGNRTNVYKEYIYNLEKLTVFVENKARLETSTSGSKCASISRLNNALFRRTLHFECPDQLIGRYVYVKAYGVPRWNRLYSAILCEVRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGM6</accession>
    <name>A0AAV4TGM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_152341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011315">
        <property type="protein sequence ID" value="GIY45758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12843" checksum="819956699E869D05" modified="2024-11-27" version="1">MWIPNIHVTAFKPEACDTKGRAFSMEMVTHHVREMNMHEPYPAPAPAPLWKVYIKTKSRKMWCRRTYVLPLRWPCKKYYLNSISDLTEYVLYQCVTYYRSSFVICID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUK0</accession>
    <name>A0AAV4TUK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_187711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011723">
        <property type="protein sequence ID" value="GIY48537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="23885" checksum="4D2029EA66E7F26A" modified="2024-11-27" version="1">MLDDDRLKRHGYGVAMMMINTTKSVCLRKKGIYPSRKGIDAQWFGERDNIKDGNVHDDVLGADEQAHVHDGSDHDEDVLYVDDHDKDVLGVDDHYDDVLGDDVHDDVLGDDDHDEDFLGDDKHVHVHDGGDHGENVLGYDVHDDDDHDEDVLGDDVLGDDKQIHVHDSGDHGRDVLGDNDHDEVVLDSDIHVHAHAGDDPDDGFHHDEVHDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZN2</accession>
    <name>A0AAV4TZN2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alpha-latrotoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">AVEN_246182_1</name>
        <name evidence="18" type="ORF">CEXT_46371</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="14">Homotetramer in membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cationic peptide 01 (latrotoxin) family. 03 (alpha-latrotoxin) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011965">
        <property type="protein sequence ID" value="GIY50328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="12" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY50328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="25263" checksum="843DE4738F754685" modified="2024-11-27" version="1">MDIVAQNVLEEDHTTTINIYKLNYEALIFTLVFFFVIVVMIFYLWKGKRIKTMKPPVPVIYYLAKTAYKKEHEELCMALIQKEEYDLNYTNSDLQLSTFLCACLSGNADLVSFMIKKGANVHTVSSYGDSGLYLAVYGLSSKTSDFKILDILLSAGCDINCQNDNGFTVLHLAGSKGNFSLVNYLLEKGADPTIASTDSVLPYDMAVIEGHEEIAQYLKNKRCIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U087</accession>
    <name>A0AAV4U087_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_58571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012075">
        <property type="protein sequence ID" value="GIY51163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U087"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12869" checksum="ABCAA1240833ED27" modified="2024-11-27" version="1">MILGKKKRKVIEEADDIKFLVQKNSLTPTTSRPRVISPAEHLIFVHRTNPVLKRGWDRYWGRQCILGTFSKVPAHRSINNVSRTQKLLFVSVGTVVKFIFLTINPLHYPHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3S4</accession>
    <name>A0AAV4U3S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_444491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012235">
        <property type="protein sequence ID" value="GIY52390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="21244" checksum="F033A229B3ECF11A" modified="2024-11-27" version="1">MPHRKLITLDQITPRGMEWGCVDITCKLTRDPGPAKNLSIPPPLFWSVSTGARKCDAKIASAGGRTQPPLLKPFPAMSYIKLPNAGRLMSGCCSARILLSRVKIINPTTFSEPIGLKKKEKVVQKTEEERKVAKSRPGVLSPLQQLLRFCCNGLNNASPTFQPCKFDTISQLLSSNNIIIFAICAILVNNTKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7A3</accession>
    <name>A0AAV4U7A3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Formin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FMN2</name>
        <name evidence="3" type="ORF">CEXT_414471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the formin homology family. Cappuccino subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012393">
        <property type="protein sequence ID" value="GIY53697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030866">
        <property type="term" value="P:cortical actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45920">
        <property type="entry name" value="FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45920:SF7">
        <property type="entry name" value="FORMIN-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY53697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8583" checksum="D470F8D62B018FBE" modified="2024-11-27" version="1" fragment="single">MFHAAFTETISSIENRLNNLKMTCDFLMSDADIQKVFGIILAFGNYMNGGNRNRGQADGFGLEILPKLKDVKKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB33</accession>
    <name>A0AAV4UB33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_296341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012587">
        <property type="protein sequence ID" value="GIY54984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9106" checksum="687A63444FF26163" modified="2024-11-27" version="1">MNEKDLEVVFAPRYVAEIFLERNGLEWPLFNLLLPMENRLRRFMSKQDLECLLGSLASLRRQPGCQGFIYKEPITEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPA6</accession>
    <name>A0AAV4UPA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_369821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013215">
        <property type="protein sequence ID" value="GIY59562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="8886" checksum="CE7B5A8C61D42649" modified="2024-11-27" version="1">MNLTNDSFIREEPFCVSHCCRVDGEETHVGAETNRVRHSASSVRRLPPVAQKVSLSNSGGTLLPTSPAVADTSVCHSRHVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQ47</accession>
    <name>A0AAV4UQ47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich PPR motif-containing protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Lrpprc</name>
        <name evidence="1" type="ORF">CEXT_683711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013261">
        <property type="protein sequence ID" value="GIY59995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQ47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070129">
        <property type="term" value="P:regulation of mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033490">
        <property type="entry name" value="LRP130"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46669">
        <property type="entry name" value="LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46669:SF1">
        <property type="entry name" value="LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="964" mass="111402" checksum="6784BFC6CCA0E10A" modified="2024-11-27" version="1">MMPNLYEWKQEVTNAMIILINKNMDNYAFKLLLAIATPESNFPNLFVKQLINKDKPAEEVIKFCEEIFKQEILLALIESDPNKNSFVQPQLFHALLSCFKNKEEGIWLTLKKMFQFGVPADLNIYSNYVFPAVTTSCPESVLSEIEKTGHSVTTAIDPLLKYYCYHGEFANALYIIQKYPVTLSQSFFNIENFVNSRVHKDNKNNSEVYYQVISFLLKNVGAFKQDHEVAFGRNLAALIQINPSLFENLLDNSDKQFEVSNKSLLICRNILRKKNPKLLNYIRRLNNFESHSKGMTDAEEVEKLNLLKVNISLSFRKGLSTSGFLIECLHFYLKQKNIPKINELKEELDKVTVQYPPSLLSELLNFHSANGDLEQAQKSFSDLKENYPSFKLDSVKVFSYASLLIKYSKFDDAINVVNSESKELHYTAISSLLKSLKKLLTIAVETGSVDLVKNLQSSLLNHIEFLHLSYFHDPLLKICLYKNDLNGAIEEFRRCIENHQIAPCLRLIMKKCIIMENPVKLESVIQIASTLLGREVVLYELVITLLKFNRESEAMKVMKNLRTKNNSGCLEDFCINMYNLNQKEELIDFVKFICVADHVNRESIVQCKNDFKTAVNLYNVTKDLFQLNDETRNLLFNLISRNKQNVPFTVPETNYEGKTSFVVSEVVSKFLQNMNEEDAHQALEQLQNMKKVEVRSISVDDMSKFLDMLLQKRSLNDLSKNVHAMDYIKDNMPKILKPLLEKYSSSGDVDAINEMKKNFPELAFMKNYYSKAYIVSERYEDLLFAYENNLNEARSIFKMSAFLDILKRPHLEGRAISLAKKYKEQDFDLPIAAVWAHCLTNEHYRKAEEFCKLFSISAHLVGRMVSKVAREKENVTMAMNYLSAIKDIDCQNKHKENAYGTLLDILVLKEMYDDASLLVVEAQEKDINLEKHYRSTLVMLKNALQRERKNVPFTIQSEDFAVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYA3</accession>
    <name>A0AAV4UYA3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_365541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013654">
        <property type="protein sequence ID" value="GIY62701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13181" checksum="DA9A8B5CAEECFFF7" modified="2024-11-27" version="1">MATKESISKSLISANLPSAAFQHIKCHLYRVFLVIITGQKPVWVQIKAILRQLQWPDLILSPCTAEVNPDSAMSSPKPWGRFSFPPGFFPAIPLDLDYHQHPPSFLRGPFDDLINNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V431</accession>
    <name>A0AAV4V431_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_302881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013918">
        <property type="protein sequence ID" value="GIY64741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V431"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="27649" checksum="F87A23CF95E8BD26" modified="2024-11-27" version="1">MLLSSESTFVCGGCLRRRKILFFQYFVHILLHADVPIAADHSLFPKRLRKTIARHRTAVVTSSQRGDFSCLGDGFVLAHQWSMNGAPYYGQRHQRRISRHLFPSAVAKGNDKGARNSPFAPPSSIFAHITWVRSDRHGSNKAHTFPGLAQRSKGALFEIHWVTGEKKNLSVRPSRPRRSISNTAKYTSPRNKEQIRKGRRGTFVGEQTKSHPAPTPFSSHFIVFKGRATSGCDQRGPPSWIQLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4D1</accession>
    <name>A0AAV4V4D1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">inx</name>
        <name evidence="13" type="ORF">CEXT_420521</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013924">
        <property type="protein sequence ID" value="GIY64790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4D1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF43">
        <property type="entry name" value="INNEXIN INX4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY64790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="268" mass="31998" checksum="989E989609AE7290" modified="2024-11-27" version="1">MARQLFGDNIVCHSARASLSQSYLDNKCFINGTMTMDEKFQPLVYHDYYQWVAIVLLLSAFTSYFPFSIWSRRCGSYLNELTTKIHDDSSCERLYKLVEKSRGNYMFWKIWALEWYYMVHFVVHGIVFDKFFNRVWTDKGWSWTAIDTLFPESGFCNFDYFNGGDLTTGKFVCLLPLNSVYRKVFWGLYVLAIFLIVLQIITFFYRVLTVIRFGNKWVNVWWVLHVAQSEAQTWESQQWIKQKWKRMMAGRPVNYIPPLMMEDNETKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V861</accession>
    <name>A0AAV4V861_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_217275_1</name>
        <name evidence="2" type="ORF">CEXT_692651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014096">
        <property type="protein sequence ID" value="GIY66218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V861"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10896" checksum="F8FD5217B6E99167" modified="2024-11-27" version="1">MNKRTLQPVSNCFRVALFGCQRNTQEGFLSVLESLTNSAFLTHTGDNTPSLFYRTVNSVKVFGDELNICESEYQDNEDDEMDPTRTAEDMQSSIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V947</accession>
    <name>A0AAV4V947_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_503001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014119">
        <property type="protein sequence ID" value="GIY66466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V947"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="12014" checksum="677666E7E9252F61" modified="2024-11-27" version="1">MYYFALTYKNGTVRISSLPKSKVSDEEAKSTEILLTALPSEYEIYLKNNHRQTTTQERRSSSESLCLLFSKIKEKYNGVPPEENPLRLRQVKITAIAGFMYSGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VC95</accession>
    <name>A0AAV4VC95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prosaposin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Psap</name>
        <name evidence="3" type="ORF">CEXT_229011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014263">
        <property type="protein sequence ID" value="GIY67633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VC95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.10">
        <property type="entry name" value="Saposin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011001">
        <property type="entry name" value="Saposin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008139">
        <property type="entry name" value="SaposinB_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00741">
        <property type="entry name" value="SapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47862">
        <property type="entry name" value="Saposin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50015">
        <property type="entry name" value="SAP_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saposin B-type" evidence="2">
        <location>
            <begin position="43"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY67633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15252" checksum="CDDE6709A0504454" modified="2024-11-27" version="1">MLASRMDPTMVCTVSGMCFPSKKNMELEKHIFKYVRDYFLKNKDSQCAECTQMMTDVQAFLQSTPEDEAKTYMEKFCHEKLPSYLCNIAMNEYFHEIYTYIKTTDAAKMCSSVGVCPQKCEVQLSQKLRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFN6</accession>
    <name>A0AAV4VFN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dhdh</name>
        <name evidence="2" type="ORF">CEXT_142341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014369">
        <property type="protein sequence ID" value="GIY68373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7344" checksum="8D0150F083479DAB" modified="2024-11-27" version="1">MATKWGVVSAGKICNDFVVSVKSLGSNEHEFVAVAARNLSSAKLFSAKHCIPKAYGSYEELAQDPEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWM5</accession>
    <name>A0AAV4VWM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nrf-6_65</name>
        <name evidence="2" type="ORF">CEXT_208191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015152">
        <property type="protein sequence ID" value="GIY73999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF0">
        <property type="entry name" value="O-ACYLTRANSFERASE LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15517" checksum="FD2BC07198E09807" modified="2024-11-27" version="1">MIVVAFFTTLNTYTNNGPLWPDYDVDANCKVSWWWNLLYINNFQTSEKQEFCWHIICTKRKQNNSPKLNLIILSVGWIVASSVSLACVFGLYNHELTRRSLLLQQFKSHLLRFWVSMGYFCMRHWPRRCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0I9</accession>
    <name>A0AAV4W0I9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015380">
        <property type="protein sequence ID" value="GIY75714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9614" checksum="EA4646C7A66430F0" modified="2024-11-27" version="1">MLYPSLVHSDSLFKNLNGTLNSHTREITEQKIFLKLPTFLVGEIYSEDWMRIRNENYMSGRLRTSSGWGGGQMSPDYPSDLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4U5</accession>
    <name>A0AAV4W4U5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hemocytin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CSH_0392</name>
        <name evidence="5" type="ORF">CEXT_399321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serine protease inhibitor-like (TIL domain-containing) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015552">
        <property type="protein sequence ID" value="GIY76919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19941">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000055">
        <property type="entry name" value="alpha-tectorin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050780">
        <property type="entry name" value="Mucin_vWF_Thrombospondin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036084">
        <property type="entry name" value="Ser_inhib-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002919">
        <property type="entry name" value="TIL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014853">
        <property type="entry name" value="VWF/SSPO/ZAN-like_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11339">
        <property type="entry name" value="EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11339:SF386">
        <property type="entry name" value="HEMOLECTIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08742">
        <property type="entry name" value="C8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01826">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57567">
        <property type="entry name" value="Serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWF/SSPO/Zonadhesin-like cysteine-rich" evidence="4">
        <location>
            <begin position="2"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="TIL" evidence="3">
        <location>
            <begin position="46"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY76919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="22727" checksum="348D018449AB0CB1" modified="2024-11-27" version="1">MDCCNMGAEESCQCTSMGEFVLECSRAGVDMSKGWRQPDYAVSLGCTNGSVYNECGPACPPTCRDLQPVCNFQKCVDGCHCPTGTVLEKGQCISKDLCPCHYGSQHFDSGETIQQDCNAVVVFQLNLRFILGITIHTPEEAVVKLKPSMDVTVNGREMESLPIKAPGIYIGQSTSSFMRVPHLSHSGTNVLAVSTGATGLESNKMTDQSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8V3</accession>
    <name>A0AAV4W8V3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rap1 GTPase-activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RAP1GAP</name>
        <name evidence="7" type="ORF">CEXT_139081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015845">
        <property type="protein sequence ID" value="GIY79097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8V3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11210:FF:000002">
        <property type="entry name" value="Signal-induced proliferation-associated 1-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050989">
        <property type="entry name" value="Rap1_Ran_GAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711:SF32">
        <property type="entry name" value="RAP GTPASE ACTIVATING PROTEIN 1, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711">
        <property type="entry name" value="RAP GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21022">
        <property type="entry name" value="Rap-GAP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="6">
        <location>
            <begin position="148"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="459"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="555"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="488"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY79097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="610" mass="68520" checksum="47F6995D67E0FA84" modified="2024-11-27" version="1">MLSNPGPYPLIALPSGGGYWIDGIHHNYPTDCLGNPILPNYDFVPKIERDESAQLYRKFFYGKEHFNFIALDETWGPLVMSLKVDVVSSQEQLRVLIRTKEGLLQDVFHVNHASTSSLNPIQILKLMCEDIITEKFTPVLFPRASEMLLAYDEHVLVKTFKFGIIYQKFGQTTEEELFGNRTHSPAMEEFLDLLGNRIKLKDFKGFRGGLDAHYGQTGDDSVYTQYKDCEVMFHVSTLLPYTEGDSQQLQRKRHIGNDIVAIIFQDSNTPFLPSMIASHFLHSYIVVQAVDPLTPNVTYKVSVTARDGVPVFGPALPNPTVFRKNEEFREFLLTKLINAEIACYKAEKFSKLEKRTRISLLQSLYDELRIKTQEFCGIVGDSGKTEINGNSNRFLDSVRKAITSRVRSHSVETNLANSVMNKRSSSSTSNSSLSSIVAGEVSQNVPKVPKETLLKISSPNSVRSREFRNRSLDSLNSGGTPLWVRTNSSPGTPISSPDTPPPPHFKPRPSESDSSSVNSLELEHIHNGSTDLTNDSTFSTSGEISSTNCSQCTENEAIIKQYEILKQELNKLKSDKLDLLKHNLACQREIKKLKEKEVKLTTDLSLASER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPA0</accession>
    <name>A0AAV4WPA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_562731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016500">
        <property type="protein sequence ID" value="GIY84311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7898" checksum="E7AC1FDA635BF041" modified="2024-11-27" version="1">MAVDEIKSYYSALLSVGSSVTSCELCDLSFPSRSFVQNSVANSAVAPAFLINSGRSTWNREKKALLFGEISFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSC0</accession>
    <name>A0AAV4WSC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peroxisomal sarcosine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">X975_05810</name>
        <name evidence="7" type="ORF">CEXT_289431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016654">
        <property type="protein sequence ID" value="GIY85391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF10">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="141"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY85391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="393" mass="43526" checksum="94CB7D0D18C1DAC3" modified="2024-11-27" version="1">MTAEIVFDLCVIGAGMFGSSAARHASANPSIKVCLVGPSEPTDAELSKERYLDLTTMKVELPEYLTIHQLARFFLNMPLGDTRNWKNYQGLLFMILLAVFCGEKNGEFMLNFLESASDVTLVELSNETFQKEGDEQILFDDNGGGHISPRNFVVAQKKVAHLQGCHIVDSVACSTETLENGVHVVSTESNEVICAKRLLIATGAFVNMKDLSVLRPLKVTRCKETVVYLKLQKEEAQRLSAMPSIIYAKENNGTGIGAYILPPIKYPDGEYYIKIGDSPFVRDDVELKTLEELRKWYLSEGNEKMVKTHVELLTELIPGLKYTDIHRRTCATCETPSGLPYIERVSPTVTVAIAGNGKGAKFSDEVGRIAAELSITGKWDSELSPNLFQAIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1S1</accession>
    <name>A0AAV4X1S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_627151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017067">
        <property type="protein sequence ID" value="GIY88449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14773" checksum="49F9AC9B64A91E7B" modified="2024-11-27" version="1">MENPQRKLGQGTGERRHCRLIIQEERPLRMEFPCRAYFGFWSPFTLSAVDVELTASSILSTMGVSQILMTDAPKNTNKNAVSKYLKLEIMLAQPVILFIMLFVSQMRMSNMPKQSTKMKENMSPNNKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X456</accession>
    <name>A0AAV4X456_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_234111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017074">
        <property type="protein sequence ID" value="GIY88548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X456"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12859" checksum="DFBAAEBAEAFEB310" modified="2024-11-27" version="1">MDHRIIFGHNHGPQNLFGHNHGPQNLFGHNHGPQNLFGHDHESYNLFGHERRFDKGPIVDGLQNRGVLKQFTVTWVIVDPFRTKLHPSLVLRTAEEHRGISDKEIIFDLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XES5</accession>
    <name>A0AAV4XES5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_589341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000152">
        <property type="protein sequence ID" value="GIY92519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XES5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9938" checksum="3D14A744988F3D13" modified="2024-11-27" version="1">MHPLSLNVRLIDWFDFKSTESRSARKGMNASNLLPIDWLKRFKRQYGGELLAEGLTAGKFVLHTGFEVNSRKTLRSLEIRFKNPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFS9</accession>
    <name>A0AAV4XFS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017742">
        <property type="protein sequence ID" value="GIY94086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="18478" checksum="B014FC66321FFDB8" modified="2024-11-27" version="1">MEIEVDYEINTRTFPEDLLILADNTTMLILTEYDILWPRKFTNDERYREFCRKYANSIANNLYCEIFAWELKLELCPKYWSTDEATFRNCVRPFRDLARMYPYDKNAFFFYSHFVLSAANFFYQLGLEEAPMLAFLEVVSVAKSVFPNGVFDAVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ15</accession>
    <name>A0AAV4XJ15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_643641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017705">
        <property type="protein sequence ID" value="GIY93784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14797" checksum="F4E50E640FB4FC18" modified="2024-11-27" version="1">MFDEENPLTEVYFGAYDRNDEDGSCEFCECWKEFWNCGTQERLFQVCFALSYYFTFLILMLIHLAKYKTNGIVDGESEISLTAWIVLGVGVSISFAVRLYAIKRSYLDRIRQKWRFIKLLWRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKT2</accession>
    <name>A0AAV4XKT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pancreatic lipase-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PNLIPRP2</name>
        <name evidence="6" type="ORF">CEXT_464951</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000553">
        <property type="protein sequence ID" value="GIY95591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF185">
        <property type="entry name" value="LD47264P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00821">
        <property type="entry name" value="TAGLIPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Lipase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY95591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24365" checksum="DA54BEF677AF2743" modified="2024-11-27" version="1">MKTAFSKLSAIEDWVASTLVHLSKKQIPFRPISLKPLPQEIIRTEFLLFTRKNRNNPVVFPPTKLEAIFRSHFNPTEWTRLLIHGYMDGSYITSWLFETKDELLRRADDNVIVVDHSTTNMLPRIIYQQSVADTRVIGVQVANLINFLHKKLGAEMKRVHIIGHSLGAHAAGYAGLDPAGTYFRKVPRNVQLDDTDATFVDVIHSNQLEYITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLC8</accession>
    <name>A0AAV4XLC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017803">
        <property type="protein sequence ID" value="GIY94594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18942" checksum="4D34DEC16A859DD0" modified="2024-11-27" version="1">MSGLRLSRITGAARVELGASLWRRREESLVKWSSLGPLSRLKIFLRGRVGSEEAVNCGFRSGTHYGSRRHNQPTLRHRPTELQEKVSCMRVLPLKDSLWGSLSGQRGRFVVIESPAGTDDHRAQVAQGLAKWRNKGPRQLRQAFRWPNSVPFMVSEVDLCLDFAYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM68</accession>
    <name>A0AAV4XM68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_175161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000577">
        <property type="protein sequence ID" value="GIY95784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10039" checksum="819280FC240EEDA3" modified="2024-11-27" version="1">MRVGRGYYLENAVINALVARHVARGLMLLILEPGCDLRWLEDATTRENANSCASRHYGRLNAPRVTVKSDVNLVRCGAAFIFRDCAEGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQ24</accession>
    <name>A0AAV4XQ24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_510691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000761">
        <property type="protein sequence ID" value="GIY97282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQ24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9200" checksum="7ACA6D15364B3A97" modified="2024-11-27" version="1">MGKAIAVRNSIQNSSAVCFGEKCQYEERDSCEIFEEASQLTAAEDIYRRINSICSSVDSEQIMDSVCFSKFSIIFKIKTVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSV0</accession>
    <name>A0AAV4XSV0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynein heavy chain 7, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dnah7</name>
        <name evidence="4" type="ORF">CEXT_174181</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000733">
        <property type="protein sequence ID" value="GIY97066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000223">
        <property type="entry name" value="Dynein heavy chain 3, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF70">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 2, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="2">
        <location>
            <begin position="46"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="3">
        <location>
            <begin position="199"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY97066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="465" mass="52714" checksum="7894F8E789006738" modified="2024-11-27" version="1">MEKIRSSTSLCLNLIPPMWPKLPLPLKVSVGGFLAMEIYDRTAKVVAPKKAKLEEAEQQLAVIMELLNAKRSELAALEDKLAVLKRDCDESIQKKKDLEAQARLCEINLKRAEKLIGGLGGEKIRWADEAKNLKIKFENLPGDVLLASGVIAYLGPYTSYYRSICITDWVKFCMNHRIPCTQNFSLSETLGNPVKIQFWNLNGLPRDAFSVDNGVIVEFGKRWPLMIDPQGQASKWIKNMEKENLSIVKLSDADLLRTLENSVQFGWPVLLEDVGEELDPSLEPLLLRKVFKHGTIDMVQLGDSTIEFNKDFRLYITTKLRNPHYLPEISTKVSLLNFMITPEGLEDQLLGIVVAQERPDLEEARQQLIVQTAANKKSLQELEDKILFTLAQSEGSNILENEEATEVLDSSKFLVADETTVNINQSRESYKSVAQRSSVLFFSITDLPNVDPMYQYSLNWFLNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUG2</accession>
    <name>A0AAV4XUG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_448191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018177">
        <property type="protein sequence ID" value="GIY97559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="18995" checksum="37712E8AB24EF0C1" modified="2024-11-27" version="1">MLDWCFDIPHAQSLKAISSSRPVQPPIGQTSALCSFKVKHITSQNMYNQIKLMVEALCIQRLTTLSHTKKLPMAETHTIGDFYSAVVFRQRTVGSSGSKLFLMPIDAGIKVLVAHGLKPSPTPPYTLSGMQKHPVAGGVEMIYDAIKSGISIIFLETRGVTEAATFYGSRAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUI1</accession>
    <name>A0AAV4XUI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bardet-Biedl syndrome 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Bbs12</name>
        <name evidence="1" type="ORF">CEXT_765611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018327">
        <property type="protein sequence ID" value="GIY98711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045494">
        <property type="term" value="P:photoreceptor cell maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042984">
        <property type="entry name" value="BBS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46883">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 12 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46883:SF1">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 12 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="346" mass="39644" checksum="F12B373C1B2475DC" modified="2024-11-27" version="1">MLSVVEKLSHGDFDCMNLICDIWIKQAKSSDCLEFNINGIIICPVTMHCSYSTVVDGLIIKSNQSHLYTQDLNIESCRALIIKGSITYEYVHLGYTENISVTVKKSAEQLQISTKELWIRKCCDLLSELEVNCLLVTGDVETDLESFCSANSILLLPGISWTHLQDLCISVNEFPCTYLLDCDQENIISNLIVKKWNFDYNESLSDTLYVHIDFMNIKGKNKLYTVMLCHPNQFLLNSQEHQFWHLASRLHSATKNNILLPGGGKTEKWCFDLLQKSPSENEIKDRIRVAISKGFLSYSQMISNKNIREEICNALDEMQSKVQAWRSAMALVLTVMQCDFFDFKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XV00</accession>
    <name>A0AAV4XV00_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_203180_1</name>
        <name evidence="2" type="ORF">CEXT_247451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000937">
        <property type="protein sequence ID" value="GIY98567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XV00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9328" checksum="C06E282F46F81BC4" modified="2024-11-27" version="1">MSFSIKDDSFPGCSSSRSHIPLRINMLHIPNPVVTGDSVRLRCAYELGNETLYAVKWYKNMGSSSDTYRPPTHRSRSSHRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1C8</accession>
    <name>A0AAV4Y1C8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_734501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001127">
        <property type="protein sequence ID" value="GIZ00155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1C8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9412" checksum="B617624D2989EE5F" modified="2024-11-27" version="1">MNKIVRALPDPTPTRQHSFLRTSLFAKCSFARPAPLPLRLTNQAKDDSGQREPVVPPPSRGGCCSHLYHWSYALQVSVWVSPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y442</accession>
    <name>A0AAV4Y442_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_4711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018701">
        <property type="protein sequence ID" value="GIZ01669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y442"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11932" checksum="318024230D36E273" modified="2024-11-27" version="1">MAAVEVLTEFFCFMCYKDKEERYECYEQHVLLRRKREQPSDTFYSCVECKAEVKEVISVTAFFDSFRDSVFECTGCDCDVENKESLQFHAECGCTTRRISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4Y4</accession>
    <name>A0AAV4Y4Y4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_535241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001435">
        <property type="protein sequence ID" value="GIZ02307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4Y4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12094" checksum="251C5ED26AD0D349" modified="2024-11-27" version="1">MSAFKSDFLIRANLLRLPLPNGVRDQGWHHISQLDCMCNETTDLLAKEGTSDVPISNDSMTFSEICSKIKTSNQQLWKILQFSPSRPSWCNYHQGLTTTLSRPEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YA60</accession>
    <name>A0AAV4YA60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_101971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018899">
        <property type="protein sequence ID" value="GIZ03085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YA60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10308" checksum="2312B038DF09738F" modified="2024-11-27" version="1">MLSHLANENKKGKGASKSEISVDFLSDHSHIPALLTQSMSQPGAQPNSDQKVHCCEIELHQQHKRCGLLQCLWHSTHSLKIKVGSLLQWQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAK8</accession>
    <name>A0AAV4YAK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ankyrin repeat and LEM domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Ankle2_0</name>
        <name evidence="1" type="ORF">CEXT_271131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019059">
        <property type="protein sequence ID" value="GIZ04272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="19557" checksum="08DE398DEABBE9DB" modified="2024-11-27" version="1">MKVDWTEYFPTLDVFANFTTKEGLNILENHLNRLRHDEPLYLPAVEPSEQSIALVHLYPSHENPSLQSQCICIRAFQQNTEKFDIKHPVYIQGSTLSELDIDVYLAIQDCELRPDEYPNVYKWKIFIKSEIKCQYSMKRSLTPLPRDLTPIKPRAEMKIISRKKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE37</accession>
    <name>A0AAV4YE37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_746701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019092">
        <property type="protein sequence ID" value="GIZ04480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8738" checksum="A2DA10788785DCD7" modified="2024-11-27" version="1">MAGNLKSPKEKGEKKRKNPLLENVEVALPWQRVPSDFSFFRFPPLTKAKRPSISPAFSIEKGQLDVKMSTKLSVFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3Z6</accession>
    <name>A0AAV4M3Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_22733</name>
        <name evidence="1" type="ORF">CEXT_765271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001805">
        <property type="protein sequence ID" value="GIX66597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9776" checksum="FEFBB480338B523D" modified="2024-11-27" version="1">MTEKTEQVETEAKLKAVQAKLDTKLRHERTNLRRRCIVSANVFDEIHRKADIEKDIHVQYNKINEKAERLFKVDEEIKDLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MA85</accession>
    <name>A0AAV4MA85_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_143201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002019">
        <property type="protein sequence ID" value="GIX69145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MA85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="45"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10205" checksum="EAECB1D971560C90" modified="2024-11-27" version="1">MDSTPNSKCAFLHLKLGKKYNNNKSKCTFHTERDIELMLHENVLCDVKLRTGAETFPAHWFILSARSPVFRAMCQSDMKEKSSRLHPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ME63</accession>
    <name>A0AAV4ME63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_3021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019650">
        <property type="protein sequence ID" value="GIX70140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ME63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13965" checksum="A0B4279B0D310640" modified="2024-11-27" version="1">MMMSVFNDDDKRLMMMMLVFNHHDDVGGVTNVLWRHVKEVDVPQQPLLLPIDSRANGTIHVSAVAAHGECSARDVSRQTRMSYGSIWKALRITLKRYPYKLQHKQELKPPDSPRFCEFGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHC5</accession>
    <name>A0AAV4MHC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_637711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002245">
        <property type="protein sequence ID" value="GIX71695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10071" checksum="E3F4D9D4E0FDD008" modified="2024-11-27" version="1">MISTPTTEVDFTSPQIFRESLSNAVPLPILRPNMPRKIQSGTSYIVGCGHWVSLFWQLAKESYAHFIYYFSREYFVPNRIPFRIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLU0</accession>
    <name>A0AAV4MLU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CUGBP Elav-like family member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">celf2</name>
        <name evidence="4" type="ORF">CEXT_611921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019937">
        <property type="protein sequence ID" value="GIX73300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000016">
        <property type="entry name" value="CUGBP Elav-like family member 1 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="279"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX73300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="364" mass="37844" checksum="6C5B5B383BE8F674" modified="2024-11-27" version="1">MFINGNSSPITSSLWSFLFFFNAKTTGRNTINLLVTAINPLVVKFADTQKDKDQKRHCQLMANILNMASLANIGGVNPQFLVNEAAMQPGFGAFANIPQVSGGLGSLSLQQQITALAAAQAAANSNKHKSHVLLVSLLDLNSASLQSIATLAGLANTSGLNPVLMQNLAALAAAGNSSPSGLNLSTSGNNSSTSSSLNGINPISPVTNMGLGLSTSSLGSLSGVNGIGNKAALSANGASLDALTQAYSGLQPYSGIPFTQIGLQPPSPAGKQIEGPEGANLFIYHLPQDFDDSDLAQTFAPFGNVISSKVFIDKQTNLSKCFGFVSYDSPSSAQNAIQSMNGFQVGMKRLKVQLKRSKEASKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMG0</accession>
    <name>A0AAV4MMG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_784241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019866">
        <property type="protein sequence ID" value="GIX72671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15299" checksum="859A2FE7CCA0F59E" modified="2024-11-27" version="1">MNFLVTIITIHPSRHILQMISLVTPKIFLVTITTTHPSGHSYQRISSVNITAIHTSGHPHSPIDLSSYYNHHPSFSSHPPNDLFVTPKIFLIIIATVHPSGHSHQRISLVIITITYASGHPHLPNDLCGQYSHHPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRL1</accession>
    <name>A0AAV4MRL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_668881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020074">
        <property type="protein sequence ID" value="GIX74524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9398" checksum="FC97FE157C1DD26D" modified="2024-11-27" version="1">MNVEDGGQSQYLCKGNKRLTNMPMWEIFSHVGGLVGCWLGISVWTAINLFEDLYKSTVKLAFKMRNRSKLLASTFISPMLPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSR7</accession>
    <name>A0AAV4MSR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_580291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002508">
        <property type="protein sequence ID" value="GIX74487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="19" mass="2137" checksum="7CA3BB986E21F137" modified="2024-11-27" version="1" fragment="single">RALENGQYQKVNMKLCLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MW50</accession>
    <name>A0AAV4MW50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Afadin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AFDN</name>
        <name evidence="4" type="ORF">CEXT_208942</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002692">
        <property type="protein sequence ID" value="GIX76762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032880">
        <property type="term" value="P:regulation of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06789">
        <property type="entry name" value="PDZ_AFDN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000032">
        <property type="entry name" value="Afadin isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028842">
        <property type="entry name" value="Afadin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10398">
        <property type="entry name" value="AFADIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10398:SF2">
        <property type="entry name" value="AFADIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dilute" evidence="3">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="278"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="957"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1381"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="712"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="905"/>
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            <begin position="981"/>
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            <begin position="1039"/>
            <end position="1050"/>
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            <begin position="1051"/>
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        </location>
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        <location>
            <begin position="1087"/>
            <end position="1098"/>
        </location>
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            <begin position="1209"/>
            <end position="1221"/>
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        <location>
            <begin position="1385"/>
            <end position="1401"/>
        </location>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX76762.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1407" mass="160295" checksum="6811520E7A3DEFBF" modified="2024-11-27" version="1">MLCLPAFLEDRDDINEEEGTTEVLAVLASAMSLLRRCRVNAALTIQMFSQLFHFINMWLFNKVVCETRTNLCTRGWGSRLKRRLSRVEAWAEKQGLELAADCHLSRIVQAAHLLQAPKGNSEDLASISSLCFKLNSLQLQTLLERYQPSEDEPLIPRELIESVVKVAENTADEQARSEGREIKLEEDSDLQLPFLLPEDGYSCDIVRGVPAGLQEFLQPLIHAGYCRLTIQPTSSGYWTIYMSDQDIGRMPSGGRSPSVHSHVDDNSSWKHHEPEVATIRLQKSNNGIGLSIVAAGDHDKLGIYIKSVVKGGAADLDGRLQAGDQLLKVDGHSLVGVNQEKAAELMTRTGPVVTLEVAKQAAIYNGLSDLLSKPSPTIQREVKNLFTDFSFDCPCPFCQSHLNQVYDHLKEDRSALYRVTEDSEDDCSLTTVRRMSERDIPTRVMHDNRPEGRLPTGPGQMMPPRMQGSKSVPSLNSNHDAEPVRVQANGTIRSHEVYNPAYSRTSSTASIPKASDYSDQHSRLKSANNLRQEIPGDSRLQYGNTPDDANPPPYPGPPDTNRTIPNSHVPPSQPNMHPPPQVPSMPPSAIQEERHYQNISVYQQPPPPPQQMTAQQPNPCPQHPRSQAHPQHPPRLLHGSQSSLSRPDPQGLQSPVDRSRPLSTLVSPREQEQYANSMGYPHPNVGPPRSPKGSQHSSVDSHYGPQNYPPRPLHDQRDFRSADPLRPPENDMRPYQDNMSHPELNNKPYPPMNPQDYNMMHMDPRQRDLLRQEAKMEEMREEVRRREDRERLIIQQQQQQQQHHNNIRMSRGATWSLPRGPVPPRLPHDFHHSQQMTGHMHPPYPGGPPAPAPKPRPQMYTNPTIERIQRPPGGYMPPLDTSIPHDANTMHPPPQPGPRMQHQPPPVVSYRYGPSGYPPRSEDGMEQQKLIRPQLMPDPRLTALPAKPANISQNSVAYEAQQHVAGHDKKEPSNLLSPSPWEREEKEKLHKQRQEEARRARDEEIRELESRPHLTPQQEDRLRALRLEQEFQRRAEELHGEEEDDDDEDLLDRAETRERKLKMQEELERARQRRLEWDVQQNQTQMKMQQQQQQQQQMSHNDEWKRQQQTLEEQEGRLRQLRLEEVQRKRELEVAKNAEEKLLREARRRQDEFKMPNAIPNQIPNRPSQPIINHQMMSNNHSHMPDHQPMPSYTIEKMNHIDNSNHQDVPPPLPTSPPPVEPSYQTVYSQKPASMRNQRLNDSHVMQQNSGGEYGKQQLEPPAPPTRKSSYEITNQMSTIGTGSRYVPSSIRNCDNGAPHYPKKSYTLDDINEVLATPLNSQNLNTYNPGNTPGVIGSQEVYRDPRQRIEAERTQQGGVAKNPGPEKLTFKEKMKMFAQEVGEPETPKDKMKISRAQREIETNLNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7X2</accession>
    <name>A0AAV4N7X2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_265201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003064">
        <property type="protein sequence ID" value="GIX80844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7X2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17728" checksum="483DCC1885FCF0F6" modified="2024-11-27" version="1">MEEEITSNVQPKETDDHSPTESLAIMLGSTPAFINCPIKALPKLQHYHFGNTSISKSQIKKDSFHQSQLIFQDHSNLLLSILLDHFHKLLAATLLKSKLLLLSPLPSPWKTTTTKNYLQFFHSFKKLKKSEKHEKQLFTMGLFTQALTTDPASNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9Z5</accession>
    <name>A0AAV4N9Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_6991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020613">
        <property type="protein sequence ID" value="GIX80660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043371717" evidence="1">
        <location>
            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7941" checksum="F5356B80754F8739" modified="2024-11-27" version="1">MAFSLATSVLAVLVALAHSRTFNDIVKMDRMMVDPDEELSPRVIGGRDALERENSLGWLHSTIKDDLSVVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDI8</accession>
    <name>A0AAV4NDI8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Apoptosis-stimulating of p53 protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">Ppp1r13b</name>
        <name evidence="21" type="ORF">CEXT_456272</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020679">
        <property type="protein sequence ID" value="GIX81447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002039">
        <property type="term" value="F:p53 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11807">
        <property type="entry name" value="SH3_ASPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000008">
        <property type="entry name" value="Apoptosis-stimulating of p53 protein 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047163">
        <property type="entry name" value="ASPP1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24131:SF10">
        <property type="entry name" value="ANKYRIN-REPEAT, SH3-DOMAIN, AND PROLINE-RICH-REGION CONTAINING PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24131">
        <property type="entry name" value="APOPTOSIS-STIMULATING OF P53 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 16" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 17" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="15" id="KW-1053">Target membrane</keyword>
    <keyword evidence="8" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="575"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="608"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="20">
        <location>
            <begin position="674"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="333"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="12"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="GIX81447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="732" mass="83186" checksum="EE2A3DED85A2611E" modified="2024-11-27" version="1">MVLLPEDAAMTLAELRQMAARQQHQIEAQQQLLVAKEQRLKFLKQQEARQHNLAEHQLDPACLQNLRDKIDTQEHKLRQLRALRGQVEQQKTNNENLGTELDSIRALFCEKEKELNLAVSKVDELTRQLDEIRNNKNRKNFIISSSATELENLKRELMYRTKLSEQQNNHICQQREDIALRQQDIAILDKKINELTQRLHRKRLLNEQLASQIHSVALSRNYNGSNFNNGFYHATNVVAVEPLPRETLESEHTRDDMSAKLHGSHKGDLGEFGLNKNDPKYQTLPYNTKFTLKANYRERLLYYQCVPRYHQSKDAKNESSVKSKIATYFQKSVINKDSSSQQEHQKKEPAESTEMPKRKSTIGQLPIKPKPLTIRKTPGLEPPKLKVQPVINTNFHRKSSDSNLASHLKVSYLPQQPEETLPVKALKSLESNNKEGTVPVLEVAPLKKEDLSEQLNAKAEVANWVEEDSPVGNKEENVENCDEPDFSESQASAEKNWYEIIETTAENESDDEKIHSAALRRMRKGNLKGENSSRNCRRVSFDPLALLLDAALEGELELVKKTAGEVPNPSAANDEGITALHNAICAGHVDVVTFLVEFGCDVNAQDSDGWTPLHCAASCNNLPMVKFLVERGACIFATTLSDHETAAEKCEEDEEGFDGCSEYLYSLQENLGVMNNGIVYAVYDYEGQNADELSFKDGDMLTVLRKGDDEESEWWWSRLLDEEGYVPRNLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NG13</accession>
    <name>A0AAV4NG13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_97291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003332">
        <property type="protein sequence ID" value="GIX83423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NG13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13516" checksum="E693E38877661110" modified="2024-11-27" version="1">MPKRTLIRYDQKELSHQISSWLLALSLQVSILSETCQGLWDQFTVINHDIFLVGVQFPVRLDTNFFSVRQPKYDGNLRFLYKIQEDKIEREDMAVSFQSCQGQRCQVEAQKDLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NN25</accession>
    <name>A0AAV4NN25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Connector enhancer of kinase suppressor of ras 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Cnksr2_1</name>
        <name evidence="3" type="ORF">CEXT_75231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003570">
        <property type="protein sequence ID" value="GIX86176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NN25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06748">
        <property type="entry name" value="PDZ_CNK1_2_3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051566">
        <property type="entry name" value="CNKSR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12844">
        <property type="entry name" value="CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12844:SF42">
        <property type="entry name" value="CONNECTOR ENHANCER OF KSR PROTEIN CNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="40"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX86176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="604" mass="67811" checksum="ABCC615741E379C4" modified="2024-11-27" version="1">MFEAEKTVLKLSIELASTTQRDQFAERPHSLIKKNPASLDIAFNKEKPDEELGIHIKSTYSGCISLETPAKSCNKVEKGDEIVQVNYQTVIGWQQKKLVTAMTEHSMELHLTLKKTPSHKHSWRINKCHKWSDDNRLCCPDTCSTSNESECLRDDFNEDEDDSAFLPASANHLILNDPSLQLRLYSGPSMATVQRRATVSGASPTILKPPINIEDLVNGVPNVKTNDTFVRSISYDPAGSKFNSKFGSVFSENVNCIEPCKNNPNKEKKETPDKSADQPAVETEPVTDFNPPSTIYSYDTCSSNDINPALVLETLPVHEEEYTVLENKSLNKVDDYLVLQKEPSTNFITREKEKHCSSAEAKESCTVPSNIDITAAKHNIILYDWEGVDTEFCGRRPSAHDISNEIAGIKASEINPVLLRRASKLETSPMNTDTFQEKHIGDIGNYQVVVIAGVPQRCVPSSKEGKEKNKGFELSSHQHRVKDSFVGKFSSRRISCKDLGKGDCEGWLYKLKERKGFFPSGHHWVKRWIVLKDHFYILIKMKIWMNKMGLAAIAYDASADITTSSFTKPAIILGVANNFYSETEDSENGSPTCIRRTLENDKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NU12</accession>
    <name>A0AAV4NU12_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metalloendopeptidase</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nas-15</name>
        <name evidence="6" type="ORF">CEXT_203021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3 4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01021304">
        <property type="protein sequence ID" value="GIX88213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NU12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF897">
        <property type="entry name" value="ZINC METALLOPROTEINASE NAS-15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="5">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX88213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="18229" checksum="A65C51FEC2468B74" modified="2024-11-27" version="1">MEFARNSCVRLVPRSNETDYVSLFRDNGCYSMVGRMGGEQKLFLANACDQVGIVIHEFMHGLGFWHEQSRIDRDKYVTIHWDNIRPGTENNFQKYTSYVQQTLDEEYDYASLLHYSRRAFSRNSLPTVEPKNRRKLQYWSTVWLQPNVYQEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5Z7</accession>
    <name>A0AAV4P5Z7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_511071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021710">
        <property type="protein sequence ID" value="GIX92662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5Z7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17401" checksum="E2F05EC0BFAD86F5" modified="2024-11-27" version="1">MGDRYDLMLIRSLRILHTLTPLTGNGFKNYFQTVTFKLLDVKRILFAFAFVALAALVKSNRSKGKDSMVILTNMVTKCPLSINLMDMNTINMVDTVTAKDISTSSIMDIMDTMDTTDTTIRAPMGFYSLENPLRYSQHSGGLVSEHDEASSRFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8E8</accession>
    <name>A0AAV4P8E8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_609211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004020">
        <property type="protein sequence ID" value="GIX91392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8E8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9909" checksum="6AB7B031BC95A826" modified="2024-11-27" version="1">MAALEVSCLLKSAERFSQQIERSGAFVEKTGAQKYCKPQGVESVLTEKNEKKKKKKNEQPAMACNHSPPNSNDSNSFVAECVVITQFGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9V8</accession>
    <name>A0AAV4P9V8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_514951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004159">
        <property type="protein sequence ID" value="GIX92780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9V8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11050" checksum="36E9A37A4EF1E594" modified="2024-11-27" version="1">MMKRSLHHPIDFSGVGFGTHHPSSLLDDSSQTGEIAGRKRILRIHLSLPFVDPVCRGARGPWFLVSNHLSVADVRPFFVFWCHGSVGQVSRLGSSKELGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA96</accession>
    <name>A0AAV4PA96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_204521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004242">
        <property type="protein sequence ID" value="GIX93383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10034" checksum="C71574FBDE210474" modified="2024-11-27" version="1">MAILHTGSGRVHRALWHSPYFLESVWALVLATKGPLSTAVPSREERKFFEKAGIDAKVPYHPILENPRHREEHQKSGIKFDRKDFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBR0</accession>
    <name>A0AAV4PBR0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_179551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004197">
        <property type="protein sequence ID" value="GIX93116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9322" checksum="13B65729A0A3965C" modified="2024-11-27" version="1">MACCDVETTLLRALVHHLLTHSESHTEKDYPNANTAHLREGNRLAHPFCLILCRLAFDEKEAFCNIRRGRWALLKRSHIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PG39</accession>
    <name>A0AAV4PG39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_768631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004507">
        <property type="protein sequence ID" value="GIX95393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PG39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12053" checksum="198074EB53D98F05" modified="2024-11-27" version="1">MTNSASNKYKKPIANRTVKILTDFTESGISKNTLNQLYYLKRKEELTKLHLQVEFPPPCYYSDPELHANLSRRESSCWMFSLLELRFYRSNGISKEVGGRIPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHZ5</accession>
    <name>A0AAV4PHZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane protein adipocyte-associated 1 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tpra1</name>
        <name evidence="8" type="ORF">CEXT_60961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0359 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004501">
        <property type="protein sequence ID" value="GIX95366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018781">
        <property type="entry name" value="TPRA1/CAND2/CAND8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15876">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15876:SF8">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10160">
        <property type="entry name" value="Tmemb_40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX95366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="23326" checksum="1B9C69C1FB492F13" modified="2024-11-27" version="1">MGGMLFWFISSIVFSMVYLVVLILPWTKLRDRLALPSKPSFYWYILFLDMLNIFQAIGSGLLYYKQEAGLCVVDVTAYVYFTIFTPLVYRTFLADFFSVTQPSIMFSYKAQVDDVVEDDNVSLPHQLSCSSLKTDSDYIYQNNSLYDSTHFDAANINPLYIHSLQSPDSFNGFEAPSMAGSINSSPAPQPQYQQVPFSTNVKKASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLI1</accession>
    <name>A0AAV4PLI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_295521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004789">
        <property type="protein sequence ID" value="GIX97504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="429" mass="49850" checksum="C1C1F690101849FD" modified="2024-11-27" version="1">MVIGSTLFQYKDIHEMTWRSPDDFTYDQIDLILIESRHVSNLLDVRTLEETMQTWMIFLVICKIRAKIAMKFTRNATGEYKLARRDEKRQHKSKKICHKENLLEEVEKLKSSNESRAFYRAVNKERKDFKPRTTLCKDKNGVIISEKEKTTPSFRLSTLELGFTGLWHTQLFHSRLLHLSVSVLWSSASLVCGIRSYFTVDYSIFPSQYFGARLHWFVAYAVISTVDYSIFPSQYFELGFTGLWHTQLFHSRLLHLSVSVLWSSASLVCGIRSYFTVDYSIFPSQYFGARLHCTLELGFTGLWHTQLFHSRLLHLSVQYFGARLHWFVAYAVISIDYSIFASQHFGALLHIYICGWRCSSLLKLEYSTEIIPMPSSMKSAEECIEKWSLKDALYPARIRTVAGNGCEDHLQHPTSMILTISLTSLLERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSG6</accession>
    <name>A0AAV4PSG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_717021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005127">
        <property type="protein sequence ID" value="GIY00007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10657" checksum="28AF55EE6E2E521E" modified="2024-11-27" version="1">MLLPRSPTSKNSFQKRHNSKKSTFHLSGKMSGLGKREVVQPVSIIKLKTREQSLLSVFFQLLWGSLSPCFHQSVWRGEKFAELSDDRNCCTGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0J6</accession>
    <name>A0AAV4Q0J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_437951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005509">
        <property type="protein sequence ID" value="GIY02839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="546" mass="59447" checksum="B174FB36188AC17F" modified="2024-11-27" version="1">MNNEICRRKIITIYFYKIISNGSDKAIHLALASPGNTTISRLSRQYSYLSPRLQAQLSLASPGNTAISRLSRQYSYLSPLQAYSYLSPLQAIQLSLASPGNTAISLASPGNTAISRLSRQYSYLSPLQAIQLSLASSGNTAISRLSRQYELSLASPGNTAISRSLQAIQLSLASPGNTAISRLSRQYSYLSASPGKNNLSPLQAIQLSLASSGNTAISRLSRQYSYLSASPGNTAISRLSRQYSYLSPLQAIQLSLALQAIQLSLASPGNTAISRLQAIDSYLSPLQAMKTAISRLSRQYSYLSPLQAIQLSLASPGNTAISRLPRQYSYLSPPQAIQLSLASPGNTAISRLPRQYSYLSSPQAIQLSLVSQTIQLSLVSPDNTAIFSSLQTIQLSLVSPDNTAISRLSRQYSYLSPPQAIQLSLASPGNTAISRLPGNTADLSSPQTIQLFRLSRQYSYLSSLQTIQLSLVSPDNTAISRLSRQYSYLSSLQTIQLSPRLSRQYSYLSITLTELQEESTLYELTFCPKKTNRRYASDSILTNVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3Z4</accession>
    <name>A0AAV4Q3Z4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Latrophilin Cirl</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Cirl</name>
        <name evidence="5" type="ORF">CEXT_284351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005554">
        <property type="protein sequence ID" value="GIY03194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3Z4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22830">
        <property type="entry name" value="Gal_Rha_Lectin_dCirl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.740:FF:000001">
        <property type="entry name" value="Adhesion G protein-coupled receptor L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001879">
        <property type="entry name" value="GPCR_2_extracellular_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000922">
        <property type="entry name" value="Lectin_gal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043159">
        <property type="entry name" value="Lectin_gal-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46780">
        <property type="entry name" value="PROTEIN EVA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02140">
        <property type="entry name" value="SUEL_Lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00008">
        <property type="entry name" value="HormR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50228">
        <property type="entry name" value="SUEL_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUEL-type lectin" evidence="4">
        <location>
            <begin position="121"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="418"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY03194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="457" mass="49503" checksum="EC653A1EB3119627" modified="2024-11-27" version="1">MKYDGFDGVLRNFGPRSETTHRYSCRRIIEMLSPDLVYDLKLEWSLLRFEVGGQKPVFSLSCLPDGNEGPIPETVSRNCVRAICQWCASRSPLHPPPRASADPRTLLHYPLEENKYRTAYACEGRQLQISCEPGHMIHLLRANYGRFSISICNEHGNLDWSVDCTSHNSFNVIKDTCGMKNSCSLSASPTLFGDPCPGTPKYLEAHYQCTAEKSAVTPSTSTTTSTSSSTSTSRPSIIIPVTPNRNARPHHVVPPSSPPAAPSTTPAAITLRDATSEAAAVAAVTTTVTTLLVDVTTTLADSLLMMISGTPETSTSEPSTVHLSRFSPENREDDPHNTMSCFPTEARGLFWNWTRAGHMALHKCPGGGTGRVKWRCDAVTVQWIPESPDFSDCSSQWVENLKYRMARGDPITSLAAELAAGGGNGREDPDDGRPPAATEGTARTSGVCIGSEQQSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7W8</accession>
    <name>A0AAV4Q7W8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_387671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005849">
        <property type="protein sequence ID" value="GIY05479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7W8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="51" mass="5736" checksum="3B9FDFA14955886D" modified="2024-11-27" version="1" fragment="single">PKSTLHLKGFASSSSGKTGRFRFEIQEFENPIPLSLRLLFSPEEISPKSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9T9</accession>
    <name>A0AAV4Q9T9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_704931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005676">
        <property type="protein sequence ID" value="GIY04158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9T9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8134" checksum="FA2840C32E164CE1" modified="2024-11-27" version="1">MKPGFRQLASSNDESVEAASLSGTLFVECATGTLLPNKTRMCPIAPASFALNMYASVFTASYLFLCSYTCAPSSGTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCC9</accession>
    <name>A0AAV4QCC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_425991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006026">
        <property type="protein sequence ID" value="GIY06967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11926" checksum="F959C3C1A003301C" modified="2024-11-27" version="1">MNVAVSPTDCCSGRMRRRRFPTKEKGNDDDFLAEPDAEKKIQPYTINLGKGFMMELKEFRNAYYIGLVKFGDVQEVRNRFNIPIDQIGVLKKAVEAMSNYVDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QEN0</accession>
    <name>A0AAV4QEN0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005990">
        <property type="protein sequence ID" value="GIY06717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QEN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12040" checksum="91A6275540C1872B" modified="2024-11-27" version="1">MKCKLSIKLNHWNNCTKFYEVQNILPLKPVINSMLSAVQSLYPLRTLRERAAGVEMRKLWLFKIWDEIRKTPAVGKTEIDFVLKSSLQEVLDSPCCPEPISGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGI2</accession>
    <name>A0AAV4QGI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_589371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006051">
        <property type="protein sequence ID" value="GIY07145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11664" checksum="D54503956357179D" modified="2024-11-27" version="1">MEREIHKSVSRIRRIRLIECHSSPHPVKFQCCSNRSWLVRQNLLMTLERCQNLSLVFYYRHSQVTSQWESGNNLLGYHGVSRKMLSFARLRITRFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QP93</accession>
    <name>A0AAV4QP93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysosomal acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ACP2</name>
        <name evidence="1" type="ORF">CEXT_63441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006492">
        <property type="protein sequence ID" value="GIY10206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QP93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10066" checksum="75021775CF91F202" modified="2024-11-27" version="1" fragment="single">MLHSPLVKDFVQKDAFLYEFWTENSGMLVEDWLDVAKLYDVIDKELKAGLKVPRWARTYLADMKRITDYAFTWIYNTATSLQLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QR25</accession>
    <name>A0AAV4QR25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_147403_1</name>
        <name evidence="2" type="ORF">CEXT_630191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006622">
        <property type="protein sequence ID" value="GIY11249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QR25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043932518" evidence="1">
        <location>
            <begin position="24"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="21805" checksum="372DAD6894896DA9" modified="2024-11-27" version="1">MAWPLKSLLIAAILLIGSKSLDGRSSSSWGKKLPIAIGEPEDDGMQVIRFGAILPHTSLITVSRSYNKKITDSLDTFNQRKKCQIQFRQVQKYLKPLIVPLPLDPSPTVVLNALCNQMLPSNVTAILYLTNAEVYGSNAASAQYLLQLTGYLGIPVIAWNADNIGLRKGDIKILKTFEANPLTRRHNKSKLQERYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRX0</accession>
    <name>A0AAV4QRX0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stathmin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_64574_2</name>
        <name evidence="2" type="ORF">CEXT_290211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006729">
        <property type="protein sequence ID" value="GIY11980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031175">
        <property type="term" value="P:neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031110">
        <property type="term" value="P:regulation of microtubule polymerization or depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000956">
        <property type="entry name" value="Stathmin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036002">
        <property type="entry name" value="Stathmin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10104">
        <property type="entry name" value="STATHMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10104:SF1">
        <property type="entry name" value="STATHMIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00836">
        <property type="entry name" value="Stathmin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00345">
        <property type="entry name" value="STATHMIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101494">
        <property type="entry name" value="Stathmin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51663">
        <property type="entry name" value="STATHMIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28750" checksum="92A05C480C1ACE94" modified="2024-11-27" version="1">MTDNESTEVRCSEHSKGGIKYELVLSEPVVESPKHVALSPPKSNLSIEDIEKKLKAAEERRQSLELQRLASLTEKLGNLETVKVKKEVFNHNFMQSSRENLEQKLESMKENRETHIKNIQEKAREIVTKVEEKRKGGNSPDREEKLEAIKRKLESAQEQREAFLNNLQEKLKEHDKHIADVKKQMDEQTESLREKSIKKLEVAQAKRESMLKEIQEKMKEHERHIEEVRQKAMSVSNDETCKENLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCQ2</accession>
    <name>A0AAV4RCQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="17">G protein-activated inward rectifier potassium channel 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">KCNJ5</name>
        <name evidence="17" type="ORF">CEXT_113832</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>K(+)(in) = K(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29463"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007763">
        <property type="protein sequence ID" value="GIY19470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005242">
        <property type="term" value="F:inward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034765">
        <property type="term" value="P:regulation of monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1400:FF:000001">
        <property type="entry name" value="G protein-activated inward rectifier potassium channel 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000078">
        <property type="entry name" value="Putative Inward rectifier potassium channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1400">
        <property type="entry name" value="G protein-activated inward rectifier potassium channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041647">
        <property type="entry name" value="IRK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016449">
        <property type="entry name" value="K_chnl_inward-rec_Kir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013518">
        <property type="entry name" value="K_chnl_inward-rec_Kir_cyto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040445">
        <property type="entry name" value="Kir_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767">
        <property type="entry name" value="INWARD RECTIFIER POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767:SF102">
        <property type="entry name" value="INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01007">
        <property type="entry name" value="IRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17655">
        <property type="entry name" value="IRK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01320">
        <property type="entry name" value="KIRCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 17" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 12" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <keyword evidence="5 12" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel inwardly rectifying transmembrane" evidence="15">
        <location>
            <begin position="89"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Inward rectifier potassium channel C-terminal" evidence="16">
        <location>
            <begin position="235"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="418"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY19470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="478" mass="53760" checksum="34C59B9FEA770750" modified="2024-11-27" version="1">MKYYFDPDLGAWQDSREDSRNPQMDLDAVSMSSASVVVEPSGARGGLYRSKSTSSKYSLKSNGTDGGAGSGIMRLSKGLSTRQRKRVILKNGNVNLSKEHVSKRKQRFLQDIFTTLVDIQWRFNLMVFAMGFLLSWLGFALIWWLICLAHGDFDHIGDEEWTPCVSEVHNFATAFLFSVETQHTIGYGSRCTSEECPEAIFIMCVQSITGVMIQCFMAGIVFAKLSRPKNRSQTLMFSRYACVCLRDGRLCFLFRVGDMRKSHIIGATISAQVIRRKTTAEGEVIPYYHTLLDVRFDNGGDSVFLIWPATIVHEINESSPFYLKSAEDMLRERYEVVVILEGTIESTGQSIQARSSYIGTEILWGHRFDQVVSFRKETGEYLVNYSKFNATNEVQTPLCSARDFYEYQKMLSEVTKVTPPFINPSPATDNSTTTTSSSREGYQRSNSSPEGRMSVNKGQEPTAETPLLAEQPPTSTDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RE60</accession>
    <name>A0AAV4RE60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_206761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007635">
        <property type="protein sequence ID" value="GIY18500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RE60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12751" checksum="E0427C539F394743" modified="2024-11-27" version="1">MRDTSLMAPRISDVIHQSENISSLLLPHTDARDTLSPLPPPNPVTSQPPRTPLETSVKQLKSQTKKQAPSFVILDIHFPAKLEKEFNLSDYRGMKGLELPIYKTEKRIIWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFQ2</accession>
    <name>A0AAV4RFQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_586481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007679">
        <property type="protein sequence ID" value="GIY18828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12281" checksum="24306707B15EA541" modified="2024-11-27" version="1">MGAFNDLGPNLPQWYNNAPGLLNEEENPKRMEKLLIEHNQTIFRGSERRAFKRGALPFKMGRIFAEIVSGREKPYIKSISLPLSIRKESDVVSLSSRAITHLRQSTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTE6</accession>
    <name>A0AAV4RTE6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Vacuolar protein-sorting-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">ESCRT-II complex subunit VPS36</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Vps36</name>
        <name evidence="9" type="ORF">CEXT_40291</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the VPS36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008478">
        <property type="protein sequence ID" value="GIY25005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000416">
        <property type="entry name" value="Vacuolar protein-sorting-associated protein 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021648">
        <property type="entry name" value="GLUE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037855">
        <property type="entry name" value="Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128:SF12">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11605">
        <property type="entry name" value="Vps36_ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51495">
        <property type="entry name" value="GLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLUE N-terminal" evidence="8">
        <location>
            <begin position="54"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY25005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="440" mass="49871" checksum="234D5593CEB8593B" modified="2024-11-27" version="1">MPVPKVILVVNDVKSKIDLMFEVIFIKLIWHQLKVLKSTAVVFSNYIYSKKQKMDRFQWWEDMSLPGENEILNQASVKLYDGNKKTLYESGNLTLSTHRLRWKDDFNPNTDLSLNLSQIVLIEKESSTWTKSAKIIAHLSAILEEDKKPGPVKYSPFNYVKFSFRGGGDKEFFNALSDALAKKAWEDPSASYPKGKKYRAGIVGIERQIRDRNEATDGTISEAFEDLKCLMKMAKEMVMLSKSVIQKLKEKQSNITEDETIQFKSQLLSLGISDPVTKSEYGSGHTFHMELAKQLAEALIKPLQEAGGILSLTEVYCRVNRARGVELISPEDLLNACLLLGKLNLPMKLHKFDSGVMVLRANTYDITDEAHKITEILSEKGSLTADELSILTKVTLVIAKERLLYLEKIGIACIDDSIEGLRFYPNCFSQKDHKFTIINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUH1</accession>
    <name>A0AAV4RUH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hexokinase_2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_225768_1</name>
        <name evidence="1" type="ORF">CEXT_580331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008342">
        <property type="protein sequence ID" value="GIY24041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="363" mass="41332" checksum="2F5DFE3AE3E1998D" modified="2024-11-27" version="1">MDEIAINGQEGMLFDMTAVLNPHTSMLMMGSYIDAKCDIALNLRRNFGLAYFEDIFNLNNLILPQSHAKEVSVEIDISKFGSNDCFDAIATEFDWGVTTVPLDFSKFQLFVGDDGLLEQIRFAFLELHHQLLLCRKCDMEDLFKNIGLSFPDIHKFLSAETHSDMISALPVTTGTPTLDDTSIASYVAKIILMRGALLTSISVILANCYLEHENFDVPHSIIWAFNFMCEDYEEAENLFLKHPVSLKQVNSIICQKIRSTQNISLIKSYSEFLRKHCTDVNVRVKAYRCMLNLLVNTNMYKEASKLVQEFMETEIPLNNLQLSSLKLLHNYCLRNLDKDHDVLTFALPIKETYSSSSESDAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWD9</accession>
    <name>A0AAV4RWD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_654101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008544">
        <property type="protein sequence ID" value="GIY25439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10907" checksum="7E3E844F4258E1BF" modified="2024-11-27" version="1">MAVSTEYLMRGELGKGRPLWVYFFVHFMARDLAEIAGQKKEEKKITAAFTSGCNNRSSTGPPGSRPREKREKGERTRDSVTSSEGGRRPSPRIKPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S671</accession>
    <name>A0AAV4S671_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_314961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009104">
        <property type="protein sequence ID" value="GIY29640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S671"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8146" checksum="67FDBCDBEBD0EDE0" modified="2024-11-27" version="1">MSELQILKTHRNDTGTYSCSAVSDIGTDEAMIQYIVQEHLIPLLTSTLSTLPVAWVTLQEVKHDGKQSCDREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S686</accession>
    <name>A0AAV4S686_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nephrocystin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NPHP1</name>
        <name evidence="1" type="ORF">CEXT_506361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009106">
        <property type="protein sequence ID" value="GIY29655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S686"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12195" checksum="387E79BF70091B6A" modified="2024-11-27" version="1">MLEGHLELENGRKLNSSIDSKSPFRKIISDESIDNLSITEETDLSKPLMDQFSQLTVNQELLPEGFRSSILFEMQKSSFYNLGNFMAPKLDETGISFSRASIMRRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJF3</accession>
    <name>A0AAV4SJF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_691611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009496">
        <property type="protein sequence ID" value="GIY32357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10860" checksum="55E558769AC0723D" modified="2024-11-27" version="1">MQRKLLLLRIVLNIMDTKTCRILNKTDIKNHPNTLQNGYQSNTNTQQNGYQNNQNSQQNGYQNTQQNGYQNNQKKKWIPKQYKFPTKWTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNK1</accession>
    <name>A0AAV4SNK1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidine-rich glycoprotein-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_146311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009809">
        <property type="protein sequence ID" value="GIY34806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043775082" description="Histidine-rich glycoprotein-like" evidence="2">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY34806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16387" checksum="5EF80F06D0CCD39E" modified="2024-11-27" version="1">MFRLLLSFLVVTVLVAYCEGQGETRPGHDHQGHHHHHHHCPPPPPCLCNTTELPSPQPQVTGNEVGSSSSEESSAEHHGHGNDHANHNHGHDHSNHNHGHDHANHNHGHDHANHNHGQGGHGHGHDHSNHTHNHNHTHRCPPPPPCVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYX5</accession>
    <name>A0AAV4SYX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_323861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010207">
        <property type="protein sequence ID" value="GIY37700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7708" checksum="50EAA829236E60A6" modified="2024-11-27" version="1" fragment="single">SESLEALVLPKWLPKCVYLTLKTSSYLYRSFLSNKIPEFSTLPDHRQTIEQLTTYHSKKGANQVLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T400</accession>
    <name>A0AAV4T400_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_155761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010712">
        <property type="protein sequence ID" value="GIY41378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T400"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10872" checksum="D03974352178B6A8" modified="2024-11-27" version="1">MAGDVEGGRPRAHSPFFSDPSPSEGRSPVTERKGDQQLKGAESQHNGSDFWDSFSTCWSFICSSPKSDSPFCMGVVTILVELTIVCSIRFKETRWCNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TK78</accession>
    <name>A0AAV4TK78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_342121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011432">
        <property type="protein sequence ID" value="GIY46519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TK78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8764" checksum="E3D2181CFC162A96" modified="2024-11-27" version="1">MYCNLFFKATVPQKPSYLFSISGQEKPQGTLTADPPPEIFHQRECLIDKSLPRFNLTLSDFEGISPTEESLVEGQVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQQ2</accession>
    <name>A0AAV4TQQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_205524_1</name>
        <name evidence="1" type="ORF">CEXT_460811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011397">
        <property type="protein sequence ID" value="GIY46308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15835" checksum="6BF52AF4A62214CF" modified="2024-11-27" version="1">MANFDLDKWLCLLDVDASSITTSSLHSAWTRSRSQNLRLEVTCRSNPRMAKRSPSCLPEPCTDRKLPREYQNLPYQSISTSYDSYGNAPYQEEFNMTKERIGGFAGSGDTRGYGAYDFPKNHHPESVEHLEVEPFFWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U092</accession>
    <name>A0AAV4U092_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_117388_1</name>
        <name evidence="3" type="ORF">CEXT_58491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012075">
        <property type="protein sequence ID" value="GIY51152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U092"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY51152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="235" mass="26309" checksum="8319CCAFC531BFE2" modified="2024-11-27" version="1">MPFLLTIKSMTRNFDGGASEEFICKDSHYCFSTVDNSCAEMRTYCIDKSLVCNGHPNCGNEDYTDEDKCNIPLLAGCGAAGGVLLLSLIVGFCLYKRHNGLRSPRSHPLNMQLRQLGTALPTRVGRPLDISITLIDQVAVFTQQQAMSCYTGSLLPVDGGIKSDYQRPIACPLLQPFDFDHPPFPWRLSVFENKGSQEIPLMARAIISVKFQVEQDSQEDRKIYDTSNHFLMEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3V4</accession>
    <name>A0AAV4U3V4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_415401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012237">
        <property type="protein sequence ID" value="GIY52412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3V4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044659">
        <property type="term" value="P:viral release from host cell by cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004929">
        <property type="entry name" value="I-spanin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03245">
        <property type="entry name" value="Phage_lysis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11998" checksum="54A820CBA0D425AE" modified="2024-11-27" version="1">MLLRSPSASAHQQSNQQAPEAPHLFRRDAASPPKADTAEWDYFTLRERLITMQKQLKEPRSAMNRHCIPGLTMSTVPDGELLWWECPGILKTMHRFSARTRIALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6L3</accession>
    <name>A0AAV4U6L3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_70081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012365">
        <property type="protein sequence ID" value="GIY53411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6L3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16312" checksum="CBD84BFE02056646" modified="2024-11-27" version="1">MAAPAPCPLDCCRHPEISRIAKGQEGSRGGETHDKERHASSKMFFFRSRRLIMNACAMISYSKYDLVDIPLCLNVRNTRAIITKNYFESFDFWGHVITRLLGTLFTDMELHRYEKLWLDSKYWSQLRESGVIRGVHEIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UA35</accession>
    <name>A0AAV4UA35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_307751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012530">
        <property type="protein sequence ID" value="GIY54602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UA35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10169" checksum="D86B84E2AA556DEE" modified="2024-11-27" version="1">MSDNKFVFLFKNRENDNGTTQKSTDTAQKHSIGQPTHTTCSKIEIRCRQRKKVCHAGSVILLADKAPTNLRKCRKAIFQKAGMATQRTMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEY8</accession>
    <name>A0AAV4UEY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_344921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012752">
        <property type="protein sequence ID" value="GIY56296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13867" checksum="180A83A68A8B1817" modified="2024-11-27" version="1">MMKDSNRERQQKEPGVDHSCTFFLSVAYNDRHRIVIKTGGRFGVSITDKNLRQVQRQEKLSSSTSSSSQFCQCLLRNADHEEPRKRVVIFRSKKDTPVALIHDRLQCWPILEQYQKADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJL1</accession>
    <name>A0AAV4UJL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_440311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012985">
        <property type="protein sequence ID" value="GIY57899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12694" checksum="50B5DBBADEBF77E2" modified="2024-11-27" version="1">MRPSMSLEIQSSVPSVSRYTCKEFTSNKHLGNSKIQIKIDYACSQEILSTTSGWRPLHLPEVETMNGLFQANSHVSVLHSLVQYVIPANKERRRPLNKVVYNSISRKYTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNN3</accession>
    <name>A0AAV4UNN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inorganic phosphate cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Picot_56</name>
        <name evidence="6" type="ORF">CEXT_473781</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013147">
        <property type="protein sequence ID" value="GIY59025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY59025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="21889" checksum="E873B8B32F4B9AED" modified="2024-11-27" version="1">MAQNFHISSLLRSIGWDTWTVLDFFLLLDSSFHVSGNNTTFSITENGYWSCLPFLMKAFGEYTSSSIANWLLMKNYVTVDVLRRTCNTIGSLSGLLNGAGGSTSFIVPIIVGILTKNKTLEEWHLVFFISIAVVMFSCVVFAIFGSAKVQPWNFVEEEKDLKSIAMNDYEKKEIPPQISTIVSNGQTSPNFHNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UP63</accession>
    <name>A0AAV4UP63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_295911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013211">
        <property type="protein sequence ID" value="GIY59517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UP63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11304" checksum="D2B23E9FC842D5B1" modified="2024-11-27" version="1">MNYNENPLLTLINKNICIENTYKKKTYKTFKLLTTTESPLQLSAAQRAWGVFPPIETQQLNATFPNVDCFAESTDLKSTMKITASEMRNKKKAIPQNCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWA7</accession>
    <name>A0AAV4UWA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_576441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013591">
        <property type="protein sequence ID" value="GIY62201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12787" checksum="9A0FA0E642E2E2CB" modified="2024-11-27" version="1">MDPFSLQLMNVYPINQLLILGSFHAEKRRSIEEKNRPNLQTLSHNGPIFAPAYERVPNQPIIDPRIISRRKRRSIEEKNRPNLQKFAIMDPNMILGSFVNREKNRPNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWD9</accession>
    <name>A0AAV4UWD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_157461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013504">
        <property type="protein sequence ID" value="GIY61714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9594" checksum="463FFB19EF56E11B" modified="2024-11-27" version="1">MDGDGLEGMRPSLLKGSIVVCFWFYGEEDRAALIKVVITDISGVVSEIRELSCRSSLNGNQWMKSEDNPNLELHNTPCSEEIDPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1X5</accession>
    <name>A0AAV4V1X5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_25341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013816">
        <property type="protein sequence ID" value="GIY64033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12552" checksum="2082E1190EC7E3AF" modified="2024-11-27" version="1">MLKRHCSCKLQCLLVTEIFHKGIYVHNLSIVQQTLVSYESQRMNTNSSARTEHINNCRYDPEQFITVLLFHSKCKSHFVLHCQVCGSSGSVFPLFSYFHLCHGIIVCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2H9</accession>
    <name>A0AAV4V2H9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_613011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013838">
        <property type="protein sequence ID" value="GIY64160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2H9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="14376" checksum="DF9FCF19EFA59B15" modified="2024-11-27" version="1">MIYRYAEKFNYYYYYFFPADTVQIVFLLYGKKGKGYFWSARWTAICSVETTGRQLIALSHLYLTCKTTTEYGERYLTRFLMLVACFILCPQMSNDFHVTPTMPTHFHRFVIAHQRKFSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6M4</accession>
    <name>A0AAV4V6M4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl15</name>
        <name evidence="6" type="ORF">CEXT_517691</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014056">
        <property type="protein sequence ID" value="GIY65961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY65961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="24080" checksum="D528C4EEC4379D2E" modified="2024-11-27" version="1">MGAYKYMQELWRKKQSDVMKFLLRTRCWYYRQLNTVHRASRPTRPDKARRLGYRAKQGYVVYRIRIRRGGRKKQVPKGCTYGKPKNHGVNQLKPVRSHQAIAEERVGRRCKALRVLNSYWVAQDSTYKFFEVCLVDPAHNAIRNDPKANWICKAVHKHRELRGLTSAGSKSRGLGKGHKFNKTKGGSRRACWKRRNTLQLRRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAZ8</accession>
    <name>A0AAV4VAZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_482991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014195">
        <property type="protein sequence ID" value="GIY67064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="10838" checksum="D2316356D5B969BA" modified="2024-11-27" version="1">MRAPPPHAPFPGVTGGGVSSGGEPAAHQPPRGRARGRRGEGGRPQQAPRPPMLAVVGGGGFPGRQLRVGALQTRVRIPDAGQVHGKGMTLCEGAADISCVECSLIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDG9</accession>
    <name>A0AAV4VDG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_195361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014259">
        <property type="protein sequence ID" value="GIY67608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8056" checksum="D3E1EBABD56BE8EF" modified="2024-11-27" version="1" fragment="single">ITKPPSKPSGVPKQEQVILLQGGASGKGQERATNDSRVGSRDEMRRCSPPWNTESEGSCGCHATTSSRNAAPSLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEB1</accession>
    <name>A0AAV4VEB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_302621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014411">
        <property type="protein sequence ID" value="GIY68612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15579" checksum="53E3096B7DB417BA" modified="2024-11-27" version="1">MKTICSTTVSQITVRSHLEDNPSQEVLCMLQFLRFNCQKRLPVASAQDASVSTRGVRLRIEQRNWSRTGNGGKNFCPLTKIFKKKKKKVGPQVSRPRLKTNNRMQHAPESPPIARLLVVNLLKNLVLPLLVALIVHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEW0</accession>
    <name>A0AAV4VEW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_286991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014395">
        <property type="protein sequence ID" value="GIY68544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10138" checksum="99D196D5825B04BF" modified="2024-11-27" version="1">MEDSTPEMASQEVAYYSASPRAAWKGPLYPSLFRFPLCGATQQRSEFASRNPKSFGSLEREDIQMASSVSECASRVDEKPRKSRNKKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VI81</accession>
    <name>A0AAV4VI81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_72592_1</name>
        <name evidence="2" type="ORF">CEXT_291201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014569">
        <property type="protein sequence ID" value="GIY69684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VI81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="620" mass="71837" checksum="6A486712E0F743D5" modified="2024-11-27" version="1">MLEFCQEMKIPVNTSAVLSYIKAIKPTEIPLYKLISFLEYVKDVCRIPSPKILLHEVLERFSEELSELPSGSISKLGQMGVSLMLEFFSQEKYEYAFEILRVLHKYNINYIKLQEPLYKLPYLNILLEKNDFFFFPFKVASIAMDICLHLKRPKDAYQIYQSFPFSIPEELDEKLKVEIKCQLFGSLLKLAEHLCFIEPLGLGLVIFRDLMLRTKGFDTEKFKDFIGKIQDIYNKYLTIVLNEQQLSIALEFYKYYQSWEGETFAIEPQPQTDKFSWHLIILSSWTNFEVKSAIDKFFENLAPALSSKSNIGFDIWCTVKITFQESENDNFEINCLKESRHTIVSAKKIACNALKTLDSDIAWIEYANPHCLDIDPKTIYNYCLKECISLKSLKNLTNQLTPENPVIDNSHQSTLFKTDSNPVHNISESCHQMTSEKMILESIKQEEISSNTNEMNFNKENSSDNSNESTLKQEEISNNANELIFKKENISDNSNESTLKQEEISNSIDEFSFNDKCTILNSEVTSETISEDTSNRILDQINFKVSSSLIPENISTNAQRPVPNKSSQIKVRKRFYQATSNKWKKRISKQINLKTFNIGRKVSDIVTSRKFYSKKSKNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLW5</accession>
    <name>A0AAV4VLW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_671331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014810">
        <property type="protein sequence ID" value="GIY71451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7396" checksum="BF9078BF7A2B0722" modified="2024-11-27" version="1" fragment="single">IHVACCIFLLTRADAPWNTNLVNKFQEAAKIVVWGNAKISRVLSHHGKVSIDNDKIEPMICSHFPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7M8</accession>
    <name>A0AAV4W7M8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_628501</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015794">
        <property type="protein sequence ID" value="GIY78777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000774">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="270"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="298"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY78777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="355" mass="40286" checksum="0E8A8159A3248A42" modified="2024-11-27" version="1">MSPIPRIFYCHLKRVKYLYPSIQNTPPNIPMSVTEQSISTGSQQTFGQRNALMHQMAQHPSAFSQTECSGISTTNELPPHFSSTYHNFGESDHTLTNRVKAFILHVDTLCANKEESTLNRTDTENLKYYTKQFSLPSTSQNSMMSQEYRVSNPGAVKFKEDDNYPKNKQWTGFSYGISENTSYPSSATHIHQHNFGGGIKNSDIESHTWGHSNLVATSSENKNACIIPNTMSASEVSEKCKKNSADKTFGRNAFTLKKKMEVPQKMNSLYECSKCPMTFRRKDYLESHERCHNVEKPYVCKFCDKAFTQSGALVKHVRSHTGEKPYSCTECSKSFVTGDDLKRHVRTHTGKTIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WER5</accession>
    <name>A0AAV4WER5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_449561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016024">
        <property type="protein sequence ID" value="GIY80570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WER5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11048" checksum="77521CBE8B4A55B7" modified="2024-11-27" version="1">MGLDALSNCNPDQTREKGRERKGGGREVKRYDLMAIGYEIQDDIVLFLLTTTIIDDLGLFQFRLNKNFKENSIIFASLIHEKSFNRGVLGFDRIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WI23</accession>
    <name>A0AAV4WI23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat-containing protein 55 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NWD1</name>
        <name evidence="7" type="ORF">CEXT_56681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016126">
        <property type="protein sequence ID" value="GIY81454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WI23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052752">
        <property type="entry name" value="NACHT-WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057588">
        <property type="entry name" value="NWD1/2-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871:SF28">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871">
        <property type="entry name" value="BETA TRANSDUCIN-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25469">
        <property type="entry name" value="WHD_NWD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NWD1/2-like winged helix-turn-helix" evidence="6">
        <location>
            <begin position="61"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="328"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="412"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="495"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="498"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="621"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="621"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY81454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="660" mass="74542" checksum="3F234109AD5E49E9" modified="2024-11-27" version="1">MQSNLKDNKHVLTSDQWAHVKQRLDGKTVCPLYVKLLSSLARRWPSYKTLTDKDVPLTLDELVNIFLKDVENKYGVETIRKIATYLTCTNFGLREAEIVELLSNSEYEGPQMDTQLDNRKVEFSVIHWLDVKKELGVLLKMYYVDKRPYLYWSHKSIKNAIRSLYLPNIRDSRLCHTDLANAFHLGFLMEKDQKGSPLDESKSKRKDDWSDMLREIDELWCHLMLSGQSNDSVMLDWEVELLYCMTKQSVDVLSQDPSQLATEIINWLKPFLKQLAHPESPASGNHDDVPQSPHPPCEYPDSQHVIGCVRETQIEMYHLPSRNLVRTFSGHKNRITCLHLTLSGRWLISGSKDSEIIIWEKDTGTMTHKFSHHSSGVQCLTTIHSEALIISGSDSGVVVVSRLYTGQVIHKLENHRGVISSVAVNSGDDIFASASTDRCVCVWSLEDFCLLNTIHLSAPITHMDISWDSTFLLVACTDHSVHVRSLTTGSDVHCLYGHQAAVTSLCFARDNCRCAVGCKDGRIHLFDVHSAKMLNTLSGHTDPVTSMQAQDNDRFLITSGGNKVVVWNFFCKKEMFVPKSRSRKEDRHQEPVTCAAVSRDGSLAVSVMIMRKLTAGYSTGLTGSVSPELSGRTPSHQEAMAKRPPKSIRRFHVRKASTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIK7</accession>
    <name>A0AAV4WIK7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_670161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016219">
        <property type="protein sequence ID" value="GIY82193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="9262" checksum="431A36DFED9EDEDC" modified="2024-11-27" version="1">MLPALAFKCVFGFRSLAYKMPIKTLEGIIARIVVAVLAHHQHTRYLFLRIIAHRRYRVRNDIAKPHFEIAHAIISLLWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WN99</accession>
    <name>A0AAV4WN99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mushroom body large-type Kenyon cell-specific protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Mblk-1</name>
        <name evidence="1" type="ORF">CEXT_178071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016326">
        <property type="protein sequence ID" value="GIY83028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WN99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8545" checksum="05243136BCEF8A0C" modified="2024-11-27" version="1">MEQRDSIYSWLGATSRGADGSTEMENTLQPFTDLESETSTDWYPEDTCYFCNAKKQPPYDPASGIIPTVEGYNSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3R6</accession>
    <name>A0AAV4X3R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_715151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017064">
        <property type="protein sequence ID" value="GIY88414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7750" checksum="05F0ACCD96EADD4C" modified="2024-11-27" version="1">MENLVSPAKGFLISGCLACCEGGGYRSGIPVLLREAIAVIRNLLAQTLILWRDVVEPFLKTTSREHHKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8W6</accession>
    <name>A0AAV4X8W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_552181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017318">
        <property type="protein sequence ID" value="GIY90420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8963" checksum="DA4DCE9769F42EF3" modified="2024-11-27" version="1">MFEYDCSLLPARLFRLICANRIPLHPTTLLCGRGKVLQERTRAKCSRNLYSVYCVGCQGLGSILRTRPVLFVVNYGVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9W3</accession>
    <name>A0AAV4X9W3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_46091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000087">
        <property type="protein sequence ID" value="GIY92061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9W3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10703" checksum="F5979B73B15AB9A5" modified="2024-11-27" version="1">MNNAPCDEGVFILGIKHTQINLEKCPPKVHGYTRNLFCLSDVTHPEYLRSGTGKLFAERVPPSPKVARLKFVRPERWLRMYSVPDSKYGMRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAE5</accession>
    <name>A0AAV4XAE5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PCMT1</name>
        <name evidence="9" type="ORF">CEXT_688492</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:12706"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01017364">
        <property type="protein sequence ID" value="GIY90945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000027">
        <property type="entry name" value="Protein-L-isoaspartate O-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY90945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="234" mass="25625" checksum="167182A342505737" modified="2024-11-27" version="1">MAWRSHGKTNAELILNLKRHGIIKDPKVEQVMLSVDRANYCKNNPYADSPQGIGYAVTISAPHMHAHALELLKDNLYEGARALDVGSGSGYLTACRESGLAVGIDHIDNLVNMSIENVKRDQPGLIESGRIKLLVGDGRLGYIDNAPYDAIHVGAAAPELPQELVNQLKPGGKLIVPVGKEGHNQTLLQVEKLPDGTVRESSLMGVVYVPLTDKEAQWPGRLIRRILQRKHLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBA4</accession>
    <name>A0AAV4XBA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_518071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000043">
        <property type="protein sequence ID" value="GIY91703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11688" checksum="253B762AE074CA1C" modified="2024-11-27" version="1">MQPPPPQQPFVIPKELLQETDALHEEISSPLPSRMNINAKYIAYTVPKTRKNPKLSEVSSPRTSVSKPKKRTTSERSRTLSSRESSPDMSEIQPIKWTSWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCS9</accession>
    <name>A0AAV4XCS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_730171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000080">
        <property type="protein sequence ID" value="GIY92015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF5">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12566" checksum="EF21579B74276B4A" modified="2024-11-27" version="1">MQQVFTGLTSYLTGKNTTKCKVLQTVAKAYDPIGFIAPFVIRIKFLLQELWQLANCVCQIQDQVSPSQWTYSKGTENPADSVSSGLATSNIYNKSLSIPWSSMVEEGNLLTSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDX0</accession>
    <name>A0AAV4XDX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_675861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017506">
        <property type="protein sequence ID" value="GIY92161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10987" checksum="0028F061FFE1E7B5" modified="2024-11-27" version="1">MTAVLFVLSAQSPLELSNLGKYVSAIRGGTRPESCLHQGRGRMNRIYEWLRNGLKEHRISFGATYRSSMVTSMGYHLVEIGYRCNLILCCLLCLGFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHQ6</accession>
    <name>A0AAV4XHQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_89182_1</name>
        <name evidence="2" type="ORF">CEXT_781731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017727">
        <property type="protein sequence ID" value="GIY93983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8428" checksum="96B34ED36583198A" modified="2024-11-27" version="1">MASDSEYRLPLKRRKISRRKLRKHPKIHKGDDDIPTYREGKATPAARRYRIVRRKRLTRTKLTIIYGKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHU8</accession>
    <name>A0AAV4XHU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_98551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017758">
        <property type="protein sequence ID" value="GIY94217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8266" checksum="2244FF9E323529F9" modified="2024-11-27" version="1">MALFPPPPAPKTRLLHEEIKAVKNIPKLTSSYIFSNLFNTTSDGTFLPPPPKNTPAAESKSSASEWAHILITRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJD0</accession>
    <name>A0AAV4XJD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized oxidoreductase ZK1290.5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ZK1290.5</name>
        <name evidence="2" type="ORF">CEXT_299351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017752">
        <property type="protein sequence ID" value="GIY94154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF10">
        <property type="entry name" value="ZGC:110366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="202" mass="23326" checksum="00E959727D09AF31" modified="2024-11-27" version="1">MLHWPLCPSNFMDKETVLEDTWRELELLYDEGLCRAIGVSNYNIEDLEKLMDSASVTPHVNQVEFHPFQNPIELREFCQENKIQMEGYCPLGKGKLLGEKAVIKVAKRCGRTPAQILIRWSIQNNVVTIPKSTQVKRIKENCGVFDFKLTEEEMNILNNLHDGRRIVDISSIQEKIDSCLPDGYKLKLANYESDTINYRNCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM04</accession>
    <name>A0AAV4XM04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger protein 91</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ZNF91_24</name>
        <name evidence="9" type="ORF">CEXT_90971</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017855">
        <property type="protein sequence ID" value="GIY94981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002349">
        <property type="entry name" value="Zinc finger and BTB domain-containing 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000744">
        <property type="entry name" value="zinc finger E-box-binding homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000202">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13465">
        <property type="entry name" value="zf-H2C2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="264"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY94981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="355" mass="41155" checksum="A2D0D2C8B3F9467A" modified="2024-11-27" version="1">MATFTEVILPEQSENIEKVAETEIPKKKSKGHRCYFCGQKFMDKNVLRKHISIHKDRDFFCNVCGKAFSAAWGLRKHMKTHTGERPYQCEHCGKAFVQKCTLQFHIKAIHGNKPHPKCKTCGKRLKSFSYSQCWLCRYEGKEVLPETDSHLQQIEDYSVDKLNNCDSQAIEFMDLDTGLCREGETVDVMSLNPDINGLNLEKVEENTVFICETCNKECSSLIQLRQHQIDDGHQQLSCEHCDSKFTSSLAMKKHLITHTQLRPFVCQKCGKDFKRDYNLRQHMITHKEDRPYVCKICKSAFKSIPTLKQHLNLIPDNMETVSDEHRKISPGLNYITFGSSKISFHRKFNRLVKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM45</accession>
    <name>A0AAV4XM45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_330951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000434">
        <property type="protein sequence ID" value="GIY94803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8711" checksum="67B856D454480F2F" modified="2024-11-27" version="1">MIHFTSIANVYKLLTALEGTFATVLAGYLAAGASRVDMFYSSLSHMMTQRGFQISIKRAFPFHNIICKILKFFVPYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQ18</accession>
    <name>A0AAV4XQ18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_193761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000707">
        <property type="protein sequence ID" value="GIY96819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQ18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="13101" checksum="5472362B73EA28DA" modified="2024-11-27" version="1">MDIEEYWLAFGISSKDTWSIQGKDMINPYDRETFHWRKRMQTSTPSFLNLQVVKVFYQRRYCFCEVVTPPLSLPFSSQFGEPPFRYLITEHIAANSRGLRSEFEKCILFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU74</accession>
    <name>A0AAV4XU74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_226741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000823">
        <property type="protein sequence ID" value="GIY97715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12056" checksum="9B548EB8C41DB46C" modified="2024-11-27" version="1">MDEQQQQNNVKLMEFRSWTLKMGKMTLFAPAQRLLSPALLQTVPICINGVLPVIKIRPKQNNVQINGVSKLDAEDTMGKMALFASAQRLLSPALSQTAHSAFMELFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVD3</accession>
    <name>A0AAV4XVD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein unc-93 A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">unc93a_0</name>
        <name evidence="3" type="ORF">CEXT_554631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the unc-93 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018229">
        <property type="protein sequence ID" value="GIY97919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051951">
        <property type="entry name" value="UNC-93_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444:SF13">
        <property type="entry name" value="PROTEIN UNC-93 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444">
        <property type="entry name" value="UNC-93 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="276" mass="31246" checksum="2730058752CDF9BB" modified="2024-11-27" version="1">MRSPCSKYNEQSRRNRCHFSSSDIHSAGAVITIPFQLCPEEIWHKSLSNHWHGNCCSLYFVKFLSNVDNYDTFSNADRLNEKEGTVTFSWSHAFATVKFNTKEEQVLLIPLTLLSSMYRSFYMAAFTKACIRCAWSTSHIGLVTVFYGLSAAVSSLLSGYVVKFVGRKCVFVVCQAVSTINLVFMLLWKPRPRQSLLFYLAGSLWGMNAGVISTQLKGEEETASSCFSVHLAAGFAISFVYDEYLCTSVKLYILLVFSCVELIGYLLTEREYQREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZE4</accession>
    <name>A0AAV4XZE4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_610211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018543">
        <property type="protein sequence ID" value="GIZ00477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15763" checksum="41D6C4A34FF6E324" modified="2024-11-27" version="1">MDDYFKDLWANAHQVTKKDRRKVVTKHDIMSALYKRAEHQGAVLSIQVPIHCSLLIQDYLKDLALFDEVLEELCQEYHGAVLSNEVPTWSSAEMDYLKALWATVRQVTKKKRRKVVTKHDVMSALYKRAEYQGAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y026</accession>
    <name>A0AAV4Y026_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GPS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_268119_1</name>
        <name evidence="7" type="ORF">CEXT_499291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001065">
        <property type="protein sequence ID" value="GIY99571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y026"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057244">
        <property type="entry name" value="GAIN_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046338">
        <property type="entry name" value="GAIN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000203">
        <property type="entry name" value="GPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011:SF347">
        <property type="entry name" value="FI21270P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01825">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00303">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50221">
        <property type="entry name" value="GAIN_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GAIN-B" evidence="6">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY99571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="21145" checksum="A77D4D987EBABB8E" modified="2024-11-27" version="1" fragment="single">MTRPDFTDGVNCSGCFENEVIRLTICNMAMLESVNKQVSQSKATRLYAFQCHSIVMEITSRIIGVGLGDSNDTRLLPDEKSIKIILTHPPRPSQSAPGTVLMGWETEGCSVVRSEIDFTECECNHLTNFAILMDFAGPEFKPEDENVLNILSSVFCDLFSSRRNTITCNLAVCLLAMNILVQTGLKREATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0W0</accession>
    <name>A0AAV4Y0W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cilia-and flagella-associated protein 57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CFAP57</name>
        <name evidence="2" type="ORF">CEXT_22791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001085">
        <property type="protein sequence ID" value="GIY99798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052993">
        <property type="entry name" value="CFA-57"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="649" mass="73782" checksum="B48D39E798000AE9" modified="2024-11-27" version="1">MPRCTSSAFAPSTRASSSWWGGTFLRLYRCKDEQRLIEIALHDQERTEKTFHCVAWMSSPDRAMIGTSDGKILIFQNITLLREVLVTKELIRIQRSVNVEDRNVTCILLTSDGLMCSHGTTSVLCFKEDFKLHKVLNIPHSSSESRVVQLAMNLRKAYSQWLRGTAGLCTTAWHSDLTEKDCEDDFRVVQDYQLTRGVICADTIQSVSLQVACSDAALTIRDFSSSSRVVLRGKLPESPCSISLCPQATSVVLGYEGAVKVYNIVFESLVESYSFETDANPKVCFSPSGHLIAFTKGSEICLYYSSGFKAHTSFQRHKAKVQNLIWRHDKCLLSSDAAGAIYEWDLLRKGPPGKHTLPEVIHTSMATPKRNSPMYFSLSVRMATYGASETAKSEVTAMVVVDELVLVGSPEGKLVGFELSLRFPIFEISHHIGSIVHLVEIREGTSIIALDTYGIASTWKFNDKNYTGATSFRTELLINVDKKEEFVREIRAMEVMLRDCTEKAELERQQLRSEHEQKEAETLQKHRDIQSALQSSLDRLKDELKTIKEYWETKDVSKIEEIQREKEENESDFQLKMVEEEKCLLRAKEERTRLQEDFEQSVVQRQDEKAGDHRGFWYQVCATSKKNRRIAPGAGKGNRKTLLEKERYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y165</accession>
    <name>A0AAV4Y165_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_434011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018521">
        <property type="protein sequence ID" value="GIZ00239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y165"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11698" checksum="E945AD0CDF0B0ACB" modified="2024-11-27" version="1">METHDYGTGNATILTYPNTTDQCTCKKQDIKSDFTDVSLDTVPEETISNKQKDIYRYEENDSCLPSPVFRTPVRKKDFINLRAKTVRSPNRSRSSECISLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1F6</accession>
    <name>A0AAV4Y1F6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_360471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018481">
        <property type="protein sequence ID" value="GIY99994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1F6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="16282" checksum="52C494E30D72D9B8" modified="2024-11-27" version="1">MYLFQKKILISKELERFQIIKRVCPLQLYTLKTIFVFAVLYAKPCSTVDEIIDAVEEAVGDESDEYQTILAGDFNINMSTEDRRTFCKVLRDVYWSHLRTNPQSLDDKRKNIHRCCLFDTRFKKCCGAYFQIFWINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1P7</accession>
    <name>A0AAV4Y1P7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-5-taurinomethyluridine 2-sulfurtransferase</fullName>
            <ecNumber evidence="4">2.8.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Trmu</name>
        <name evidence="13" type="ORF">CEXT_94501</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP = 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47040"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11732"/>
            <dbReference type="Rhea" id="RHEA-COMP:11733"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:87171"/>
            <dbReference type="ChEBI" id="CHEBI:87172"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.14" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01018534">
        <property type="protein sequence ID" value="GIZ00371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1P7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061708">
        <property type="term" value="F:tRNA-5-taurinomethyluridine 2-sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000104">
        <property type="entry name" value="Mitochondrial tRNA-specific 2-thiouridylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933:SF5">
        <property type="entry name" value="MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933">
        <property type="entry name" value="TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIZ00371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19686" checksum="78669A5ECBCB8161" modified="2024-11-27" version="1">MSGAVKKVVCAMSGGVDSAVAALLLKNRGYQVQGVFMRNWDIADEKGYCHADKDKDDAEYVCKKIGIPLMEVNFVKEYWNNVFSAFINEYKEGYTPNPDIHCNKRIKFDLFFKYALERLKADAVATGHYARIATSSEKNFRLLKGIDKQKDQTFFLVADSQISSRKMYFSCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2Z0</accession>
    <name>A0AAV4Y2Z0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_94401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018534">
        <property type="protein sequence ID" value="GIZ00351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="13234" checksum="0EE304EF07D64715" modified="2024-11-27" version="1">MNYSFPYFHAAFCCFFSRDGPQGQIYQQFSQSLVRRPCLCRVWADGRHTEPVSERERPRRWIKDRGGSTRGWRWYRLAALVSRVGFPPKLRRLPPRRRVPHTTSSPNRGVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4L5</accession>
    <name>A0AAV4Y4L5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Titin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ttn_2</name>
        <name evidence="3" type="ORF">CEXT_426681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001258">
        <property type="protein sequence ID" value="GIZ01135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4L5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF101">
        <property type="entry name" value="ZWEI IG DOMAIN PROTEIN ZIG-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="84"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ01135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21293" checksum="2C1413511C9D8A02" modified="2024-11-27" version="1">MLVCELLLHVPLRLGIHHLNLLGSRMKQKVIETRGISLRKIDEFTSNLVISKVEAESNGNYTCKVSIPLDLIRNRLFLWLKIFPKISPFHFLVNWTLACELFVVCGVLAGDPPFEFVWFKDGQKLLDTRGISIKFDEFTSNLVISKVDAESIGNYTCKVSNSAGFDQKSAFLSVKDVPRIGPFHLRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6C5</accession>
    <name>A0AAV4Y6C5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_68161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018874">
        <property type="protein sequence ID" value="GIZ02893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6C5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12250" checksum="AD7E182DC52B1630" modified="2024-11-27" version="1">MISRPQDSQPTGNVSSNMSWCYKAQGVNNGVSSIMMWRNNDECEFNLKYNIMPHTSIAITMGFSKSHRRRPLKVKSINQLFRKTLYKSANPGVCDANTLHITPTRNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7K5</accession>
    <name>A0AAV4Y7K5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_484432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018759">
        <property type="protein sequence ID" value="GIZ02122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="275" mass="30583" checksum="D57152262E7708F1" modified="2024-11-27" version="1">MNEQISPDNKAVLITSCDTGFGNAFARKLDAEGFLVFASCLNPAGPGATELNKETSERLKILGMDVTNDESVAKAAEFVKDNLGNCKLWAIVNNAGVYKRKSQGRVVNVTSLGGRVGVPHLTPYIVSKFAAVGFTECLRREMDIWGLRVIGIEPEPFRTPMTNTEVAVTRLDEMLPTLNPSIMEDYGPKYFKQLKAFVMLYDKVVSPKIYRVVDALYSAVASKYPSPIYRPSRNYFVEMSTIVTHFLPTCVMDFITRVTLFVLNSPIPKMAEKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB07</accession>
    <name>A0AAV4YB07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_679451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018936">
        <property type="protein sequence ID" value="GIZ03352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11651" checksum="DE61CF0CF6A8ED82" modified="2024-11-27" version="1">MSAVFAHSSNGWHFNHLRCNLSHLVARTPCHSFNIHKESGIPLGTWNKRPPSPKRDPLDAQAPSISLINLHLQPAKGLSSRSAPVCISVALRNKINVIGRGEVNQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB32</accession>
    <name>A0AAV4YB32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_425431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001620">
        <property type="protein sequence ID" value="GIZ03560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8142" checksum="120BAFAB3F76424E" modified="2024-11-27" version="1" fragment="single">RLERVPITPTFRKNQTDPTSSAVEISSAHKNNDRLSVPSGALIPPLGIYIRASLLSSERRLCSALAMDRDQLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCA2</accession>
    <name>A0AAV4YCA2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_381171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001656">
        <property type="protein sequence ID" value="GIZ03834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044011291" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="10054" checksum="FF3E42488E01B62F" modified="2024-11-27" version="1">MKLILSISCLLLLFVVSSDALNPSPMSENDMYRCYYVILCDLRKPEEFQQLVYTAGPETTAKAMEWMREVTKIEDAEDTQNSGKNILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3F7</accession>
    <name>A0AAV4M3F7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_484681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001821">
        <property type="protein sequence ID" value="GIX66788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3F7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX66788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12649" checksum="DF2C1A958C2F68EA" modified="2024-11-27" version="1">MTTTSDEQKRDTSKETETIDGTPIVTKTVTTVIRKIVTSDEGDDESYTTMTTTSDEQKETQVVSKTDSSQTVTTEVLKSPPEKKSDSHVTEETEETETIDGTPIVTKTVTTVIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEI7</accession>
    <name>A0AAV4MEI7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_800481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019625">
        <property type="protein sequence ID" value="GIX69851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043595989" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9216" checksum="9F3494C3DA5AC036" modified="2024-11-27" version="1">MLHYACVVCLATAVVTGIVTTVGTNEARRSPKGRRPKANAKGPYLEPFFYLDTDRLLRIFHLYEGHNHNRLEVHNSQFFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJ81</accession>
    <name>A0AAV4MJ81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent helicase Rep</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_79401</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002310">
        <property type="protein sequence ID" value="GIX72383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJ81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049912">
        <property type="entry name" value="CRESS_DNA_REP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02407">
        <property type="entry name" value="Viral_Rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52020">
        <property type="entry name" value="CRESS_DNA_REP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="12" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRESS-DNA virus Rep endonuclease" evidence="11">
        <location>
            <begin position="4"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX72383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="24968" checksum="23AD776AAFABC3C9" modified="2024-11-27" version="1">MAPRQYAKRWCFTINNPRVNDHPSIWLQGHDNYGFQYEIGQNNTPHVQGFVCFTERRSNQHVKLLHSTAHWETMKGTIKQNIEYCSKKDTSVSDFYSFNLNNFIKENPLTKLQNDCEEQNTLLQVYKENFSLSCKYHTFIQKYFGLQQKPRNHITSCVVITGPTGTGKTGQISSTISLAEFVELTIKCFGKSSFEISRPVLSPQRKHSSLPPPPTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJI6</accession>
    <name>A0AAV4MJI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Septin-8-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sept8-a</name>
        <name evidence="2" type="ORF">CEXT_275911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002345">
        <property type="protein sequence ID" value="GIX72729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="61" mass="6755" checksum="E955D481C54723CA" modified="2024-11-27" version="1" fragment="single">MSELVSNGVQIYQFPTDDDSVAEINSTMNALLPFAVVGSTDFVRVGNKMVRARQYPWGTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR45</accession>
    <name>A0AAV4MR45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-tyrosine kinase 2-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PTK2B</name>
        <name evidence="2" type="ORF">CEXT_670851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020121">
        <property type="protein sequence ID" value="GIX74992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041390">
        <property type="entry name" value="FADK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46221">
        <property type="entry name" value="FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46221:SF9">
        <property type="entry name" value="NON-SPECIFIC PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18038">
        <property type="entry name" value="FERM_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="FERM" evidence="1">
        <location>
            <begin position="33"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="23069" checksum="C66173A7E357CC3E" modified="2024-11-27" version="1">MNRICRECIQSHGDNAKFKKVDSNLTCDKQERTTLKVFLSNGNSNIVKFGETTAVKDVIDVVTKRLSETPRPFESVFGIRLVHAPSDEMHWLHSDAGMFQILMKYSYYPIDEWRFELRVRFVPKDLRDMFEKDKVTFLYFYEQEIFKDMTHVALDKKSNFEFLEKDVGLHKFLPSPVITNNKVHFIAIAKLSFLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSI7</accession>
    <name>A0AAV4MSI7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription elongation factor SPT6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Transcription elongation factor spt6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SUPT6H</name>
        <name evidence="12" type="ORF">CEXT_1391</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Histone H3-H4 chaperone that plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPT6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002533">
        <property type="protein sequence ID" value="GIX74854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00164">
        <property type="entry name" value="S1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09928">
        <property type="entry name" value="SH2_Cterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09918">
        <property type="entry name" value="SH2_Nterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000494">
        <property type="entry name" value="Suppressor of Ty 6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2740:FF:000001">
        <property type="entry name" value="Transcription elongation factor spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.650:FF:000002">
        <property type="entry name" value="Transcription elongation factor spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3500.10:FF:000006">
        <property type="entry name" value="Transcription elongation factor spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.140:FF:000004">
        <property type="entry name" value="Transcription elongation factor spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000089">
        <property type="entry name" value="Transcription elongation factor spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2740">
        <property type="entry name" value="Spt6, Death-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.850">
        <property type="entry name" value="Spt6, helix-hairpin-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042066">
        <property type="entry name" value="Spt6_death-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032706">
        <property type="entry name" value="Spt6_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028088">
        <property type="entry name" value="Spt6_HTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035420">
        <property type="entry name" value="Spt6_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035018">
        <property type="entry name" value="Spt6_SH2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035019">
        <property type="entry name" value="Spt6_SH2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028231">
        <property type="entry name" value="Spt6_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055179">
        <property type="entry name" value="Tex-like_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017072">
        <property type="entry name" value="TF_Spt6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145:SF6">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14635">
        <property type="entry name" value="HHH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14641">
        <property type="entry name" value="HTH_44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14633">
        <property type="entry name" value="SH2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22706">
        <property type="entry name" value="Tex_central_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14639">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036947">
        <property type="entry name" value="Spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1035"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1400"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1406"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1444"/>
            <end position="1457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00070625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX74854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1492" mass="171259" checksum="B1583AF0CE00CAB9" modified="2024-11-27" version="1">MVVDEEGSRLPTYDTQEALEESEGESDESDFIVDDDGQPISKGKKKKHIKYTDAALQEAQEIFGVDFDYKDFEQEEDEYDEDEIEEDYEEEDEEEGGEVRQRRKKGSRKYGTRKSIFEVFEPSEIERSHLTDLDNDIRLADIPERFQLRGVPVTKADDDEIAEEAEWIFKQAFSINTISIQEGEHAGTGHQPIAGRKNPSAVGKIREALKFIRNELFEVPFIAFYRKESVEPDLNINDLWTVYRFDEKWCQLRTRKKNLAKLFEKMQQYQCDIIMADPDKPIAEGMRTLDHSDILRLKKKHKQLKKSKIKKASKEKELVTEPEAEQETETKVKHVPHRNTYAVCKETGIDGLAKKFGLTAEQFAENLRDNYQRHEVDQYPVEPKEVASDFVFANCLKAARYMVATQLSREPAVRKCVRQTYFERAKLNVKPTKKGLKEIDENHPCFSFKYLKYKPIMDLRGDQFLKLYMAERDGFLTMDIVIDKPDGNDGRPRYIDEIKNLYERDEFSKNVQEWNVQRMQALEMAIVSILYPTFQKELRMRLLNEAKEGVIKACCRKLYNWLKVAPYQIDPQVEDEDDFDTREGVRVLSISYSPERDVPAFCALLDGDGEVVEYLRLPHLLKRRNAWREDERMLKENDLNSLRNILLSKKPHVVVVAGESREALMVVEDVKSVINDLIDSEGFPPINVELMDNELGVLYMNSNKGENDFRDYPPLLRQAISLGRRLQDPLLEFSQLCSADEDILCLKYHPLQGEVNKDDLLYALYLEFVNRTNEVGVDLNRAVQFSHTSNIVQFICAFGPRKAAFIIKLLKSHNKQLESRAMLVTFCKIGPKVFINCSGFIKIDTASLVDSTESYIEVLDSSRVHPEGSEWARKMAVDALEYDDTSEDVNPAGALEEILENPEKLKDLDLDAFAEELERQGYGNKSITLYDIRAELNHRYKDLRTPYKPPNGEEIFNMLTKEVPETFYIGKMIFVTVTGIARRKARKDQLENANPIRNEESRLWQCPFCLRKDFPELSDVWSHFDSESCPGQAMGVRVRMDNGISGFIPTKMLSDKHVSNPEDRVKIGMTLHARVTKIDIERFAVDLTSKTSDLADKNNEWRPPKDQYFDYEAEEKDTKTEVDIAKKQNRQVYLKRVIVHPSFKNGKDHLTVSWKVADDITQHIDVKEEGKENDFSLGHSLLIDGDSFEDLDEIIARHIQPMAGYARDLLNFRYYTAANGGKKEDTEKVLYDEKKKAPSKIHYYISASKQWPGKFLLSYLPRNKVRHEFVTCTPDGLKYRSKMFRSVNSLFRWFKDHFRDPIPGTTPAMSVRTPMGQSSYIGNTPSINLATLDPQAIQRAAANLPSHVFSALSQVAGQTPGAFHGASAFAAGYSGGYGYAQPYTPSQPMATPMAITPSYHAIPTPAHSQVPTPRYSQTPQQNWQHPTQTPSRSTPKSSGTTTQDWKRMAEQWAKKSQENMNRSTPRTPAHGSPSPMVMESTPADATPLIDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWP2</accession>
    <name>A0AAV4MWP2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GATOR complex protein NPRL3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nitrogen permease regulator 3-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Nprl3</name>
        <name evidence="5" type="ORF">CEXT_704781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NPR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020236">
        <property type="protein sequence ID" value="GIX76190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056603">
        <property type="entry name" value="HTH_NPRL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24064">
        <property type="entry name" value="HTH_NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03666">
        <property type="entry name" value="NPR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GATOR1 complex protein NPRL3 C-terminal HTH" evidence="4">
        <location>
            <begin position="259"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX76190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="336" mass="38276" checksum="8DDDC98463B1CA68" modified="2024-11-27" version="1">MVHSKINNWIDLSFCLPIKVHRLQDERLLVEPGDINACLKDLRPYHGLLLLVDASELLSSLPEDSSPALIRLISVTSPLKNLQQLAADADIILSHVFQLVSHLLYWGKATIIYPLCDSNVYMISPYAPTHMYSSLEAKFCEQFPNMSLLAVLSQFSLPISLSVLDDPMNSSYQQHRLLTQLHTYVYLIPPERASSSLQNGELIEDTTRTIKTLESSDLSSSYQSEESLLSPSHSKASSVSDEEDLSLREQDCIRQANLTPLERDSIIRDASHNSKDDLKNFIRFCPYFRGRHHLEEIMYCENIRRSHLLSLLDKFRNVLITCQFEDTAVVALNKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXV1</accession>
    <name>A0AAV4MXV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_290591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020200">
        <property type="protein sequence ID" value="GIX75809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11990" checksum="D4CAFEA4E807728F" modified="2024-11-27" version="1">MIRFERRSNLSIKGIEKGSFLLCVCVSFRRQGCVGGREGDGRASNTRGLLKTQRLSGLPSASRCNIKRSAEEFELGPFTKRASAAIAAISNIVLKIIFPLLYQWKITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZ50</accession>
    <name>A0AAV4MZ50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_406471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002656">
        <property type="protein sequence ID" value="GIX76274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZ50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="18973" checksum="FEBD8361A33C155D" modified="2024-11-27" version="1">MLIKPTLRSNSSHPRSCRVPRTKRVINRAHVYPERNLHPILSLMSGDFSVRWVYFQAISPTNELSLLGKPPFINNKRHAEAALSPFVGLGSTFEDIISCRGIICRVFIAPVWGLWSVVLDLWFLGLPSGMSWQTMNCIEARHPIGIGKGGGQYRKIKEANEFGGDTVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N042</accession>
    <name>A0AAV4N042_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Voltage-dependent calcium channel type A subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CAC</name>
        <name evidence="15" type="ORF">CEXT_373841</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020270">
        <property type="protein sequence ID" value="GIX76604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N042"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="3" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="117"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX76604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="224" mass="25847" checksum="5A00DBDDA7915707" modified="2024-11-27" version="1" fragment="single">MHNVRRVISKVLIIFDLPTSKKSCCKTEKLKGLRGQSEEDDEEEGDDEGMARSPYLKQSLKEKGRCKKFWRAERRLRYAIRNASKSQAFYWFVIVLVFLNTVCVAVEHYDQPKWLDDFYVICGSIFEVVWSSVRGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGAFNFPEGTPPANFNTFSYCLAYSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N1V9</accession>
    <name>A0AAV4N1V9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homeotic protein female sterile</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fs(1)h</name>
        <name evidence="6" type="ORF">CEXT_768162</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002766">
        <property type="protein sequence ID" value="GIX77562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N1V9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05497">
        <property type="entry name" value="Bromo_Brdt_I_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.10:FF:000002">
        <property type="entry name" value="Bromodomain-containing protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043508">
        <property type="entry name" value="Bromo_Brdt_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="65"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="161"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="242"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="187"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX77562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="33755" checksum="D8A258AAA6454A99" modified="2024-11-27" version="1">MALQDENENNANQNNGDNVMSKYVEPNLEPVNGIVQPLVHPPPGKPHRNTNQLHFLLKTVMKAVWKHQFAWPFYHPVDAVKLKIPDYHKIIKNPMDLGTIKSRLENYYYYTSSECIQDCNTMFMNCYIYNKPGEDVVLMAQTLEKLFLTKIAGMPKEEIELPIPTPKASGAKGKGKKGKSRVNSVDSSSGKESTSNSTMAVQSSQKSPISTSSSAISSVTVPGSTNSTTTVSASVVSSTGISQNLRSNNSLGGPSTSPKKTTNSVDKTAGPKTNSVYPNDSQSAQLPSLSPSVGIANQKGPTKVRTSVDFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N239</accession>
    <name>A0AAV4N239_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_527311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020439">
        <property type="protein sequence ID" value="GIX78778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N239"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12476" checksum="AE8B33BE170B6996" modified="2024-11-27" version="1">MESKLRLPGRKHKKRKFTTPATNIPDPGRQILGALIKFTSPVPRGTLNGISGTFESPEFRNSDKWRNNSRFLLLLPPPTVAAIVQEEGGSISPICRGRVFPIKVNQPSFETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N961</accession>
    <name>A0AAV4N961_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_289791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020630">
        <property type="protein sequence ID" value="GIX80884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N961"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="22590" checksum="831A89C97AD4EB1A" modified="2024-11-27" version="1">MNKCNFCSYETSNSTCFRRHLSVKAYWRETISVFCLLNAIFIERKFTNPSSNTLWIEAIQVQYLWKVFQAESPSCDSFCCAFKNAYDTIKSNKEALEGLDKSIECVINDNDELQKEIKDWKHSRGRDNPAKRLTRGITIKDLENDELWWFGSSWLFKDYEVWPKKKEVKVTVDETFLKEERKGNVAPQNLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAV0</accession>
    <name>A0AAV4NAV0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_814501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020677">
        <property type="protein sequence ID" value="GIX81435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19293" checksum="B59BEA6F41A58706" modified="2024-11-27" version="1">MSRHRLKHNLVLPQSQPSARHAGQPDNVAAACWKTHPRKIPRRTLLLGKYANSELEESRGKGNKRNQIKFENKRESRTKELYFTNPFSRWDVTPQQGKNNDSSNKKESDTETTVLRLLTMFWSIIGRCRDTKPDALTKSANQPAEGWGTNYGYEFAEMSLRLSDTNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBD6</accession>
    <name>A0AAV4NBD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_567531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003152">
        <property type="protein sequence ID" value="GIX81664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11683" checksum="30BCDB6F2ABF89BB" modified="2024-11-27" version="1">MNNGSAIEKDEKVLSFGPTKGIEKERYHQSKGSRSLIADRLSELIEYMHCTTGITRHAMESTANQLGRLVCIGGASVAVIVMWHLQFRCSIGIAATHCSSFAQCVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFY5</accession>
    <name>A0AAV4NFY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_277391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003359">
        <property type="protein sequence ID" value="GIX83724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="12901" checksum="3E03362A20DF244C" modified="2024-11-27" version="1">MDSPVARSAMQSYTDAPLLQGDAVVEGVEEELGAGPGEDAGGAVHAGGALVPTGVEGQGVHHARVDNFVDEQQPQVLQRLSCPQASHGDPQEQTQGVHLAGGQKVLVRCLQEKVKSSLMVLEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJI1</accession>
    <name>A0AAV4NJI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_679271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003467">
        <property type="protein sequence ID" value="GIX84969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15150" checksum="01AEB0DE5FBEB62C" modified="2024-11-27" version="1">METETTAVNKIDQNTFHKCAKITVEKTYSGRLKDHAMSEAYKQIALLQSGCMTYGDEPSIYKKVKKVEITEKVMSKMTALMISKFSSGVGRLVSVSQPNLNFERRARILLGRRMHNFAKILAQDADATFPDKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTG6</accession>
    <name>A0AAV4NTG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_415071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003703">
        <property type="protein sequence ID" value="GIX87683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9759" checksum="EEFBF6834DD99C91" modified="2024-11-27" version="1">MEIGLIATPLQPHKSITKRKTLVYMLCTPSSIIEPILYLRQQGMLLSIHSTFQTNGNAGNLLTTSGCNHFCPLVVQSQTNTRCRTRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NU05</accession>
    <name>A0AAV4NU05_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spaetzle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_46908_1</name>
        <name evidence="6" type="ORF">CEXT_54081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003646">
        <property type="protein sequence ID" value="GIX87074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NU05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005121">
        <property type="term" value="F:Toll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0021556">
        <property type="term" value="P:central nervous system formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032104">
        <property type="entry name" value="Spaetzle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052444">
        <property type="entry name" value="Spz/Toll_ligand-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199:SF12">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16077">
        <property type="entry name" value="Spaetzle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Spaetzle" evidence="5">
        <location>
            <begin position="725"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="198"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="298"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="436"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="567"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="567"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX87074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="823" mass="91454" checksum="89F38F3D34B44603" modified="2024-11-27" version="1">MNFFNQDPNFFSSLGQNNNAQSAMGQLQQPPQLGNQAKLPHSQPQRPQFTNKPSHNDYQNLKPFTNGNPSLPGVLGSPGETGIPSSFGNNQGMVQYDGSSIQSNLKNPNSDKDLQQMVQYYQQIQQQQLQSPTHAKQYPTPLANPLMSTYNESPQPPSPLPNYPPSSSSLSNYPPSQQFPSAPIQTSPYNEYQFMQGSSYQDSHSQMPGGQPAYGNNKNVPYEDSGYPSTYQASQDQAKSHISEIQNADQAGYTMPPFSPIDPLASAIDGSHQDIQEYYGYQQASTQHKSPLYSTEQIAQNGGSTGMHEISPYSDEKNSPEYENPTKSSSSKSSSSSDSTAGYMTPEQLFAPHSTGLQSEAKYGFASNHGEHSESSKDSIEAEAAGSTLNEQHEGSERAALHLPEEVSIYVARQTDNPYLYEYTEAYDPFAYDVSNDKSKAESDSSKQMDAKDAFNEAESDEKFNERIREYQKLLTKAPKNNYMVEPTQSPSLTSSPLTTTTRMPVFKKASDAEADEMKNHKTTHSYMFQYMPSERSTNTKPNPVWNSKKPNATRYHFLVPETKLQTTTTPSTTTTMTTTTTTTQAPPSFPQTSATPSYYNSVSASQSYYHEPETPACARYNNLTYCLQDSEYQSKCLLISDVSWTIRRKLNIRCQLDEIKRAIEKNRHPLDHFLVDISASSNIVDDSLNKVFENSVPLQSTSVSYSFEGKAISPSKSDSQNATGCISNVQYAKPLRAINTAGLWKIIVNVEFEETGANYTQTVRIEECSHTAGFVATCGTETISACLQQYKLYRLLAWEPHRGFYIDAFLLPISCFCGSQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWD3</accession>
    <name>A0AAV4NWD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_787601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003731">
        <property type="protein sequence ID" value="GIX88055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9140" checksum="71D5862F37A144AF" modified="2024-11-27" version="1">MNPFPNICGEIINALPFNTTVRDLKGPSKSLVQKPVPRLRESDRITMVARSITERDFWLSCWARMEAETMHQPYIACFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZZ8</accession>
    <name>A0AAV4NZZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LIM domain-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LDB2</name>
        <name evidence="1" type="ORF">CEXT_530941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003902">
        <property type="protein sequence ID" value="GIX89974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10282" checksum="B7D70067EA054A11" modified="2024-11-27" version="1">MRQMYSQPIPGGPAMDPFYSSPFSSYFRRQTPYFGQPDYRIYEMNKRLQQRTDDSDKDGPKDTLLGELLIPRYFRSIFEGGVSDLSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1H6</accession>
    <name>A0AAV4P1H6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_420751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021445">
        <property type="protein sequence ID" value="GIX89621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1H6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8162" checksum="17CADDABD5925744" modified="2024-11-27" version="1">MYHILCTKIDLCPDKWPGADRSESFHKAVMGSGTMRVFSDMIDVLTAPRESRKTIQFKGGLDNGRSQPGDDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1K8</accession>
    <name>A0AAV4P1K8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_309391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021393">
        <property type="protein sequence ID" value="GIX89112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1K8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10887" checksum="5C408A4EA56C6F23" modified="2024-11-27" version="1">MPTMPIWRSQCHAQFCESLSSSAKDQAHQDWEAPEDPTAKHAPKALIIAHQKPPPHGEASRGREEIFSSSSHRSHRNRFKLSDVPVAPKTPIGSIQVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3W9</accession>
    <name>A0AAV4P3W9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_134678_1</name>
        <name evidence="2" type="ORF">CEXT_643331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021514">
        <property type="protein sequence ID" value="GIX90614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3W9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11406" checksum="4DD9D43B47DC9C62" modified="2024-11-27" version="1">MDGLLDVPSIPHPKLSAAQKQHIKERSLSPTDRHSHVPIRPFLTKGSVAERVLLFECCPDRALERTSSGNKSKQNLISTWRPGGSDVQNKTHVSYLKYLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6H6</accession>
    <name>A0AAV4P6H6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004111">
        <property type="protein sequence ID" value="GIX92254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6H6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10827" checksum="07DCD2AEE2440212" modified="2024-11-27" version="1">MCKLTHGVGGRPSGLLVKSDIHVPQDKKLIFKTPMGMFYNKVSQKNDPRFSEGAIITPCWRQASRLVNQPTAPETKATKMLRFIYPWWICGFGGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDN9</accession>
    <name>A0AAV4PDN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_169771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004490">
        <property type="protein sequence ID" value="GIX95305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX95305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8548" checksum="CBBA336AD328843C" modified="2024-11-27" version="1">MQDHLGCLEREGRKCHKPPRKPRPSPSEKRFFNSRKTDQTLAYTNAMHGKLRTVLPLIQLLPSALLILLVGTLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PFY6</accession>
    <name>A0AAV4PFY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_653341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004443">
        <property type="protein sequence ID" value="GIX94880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PFY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9796" checksum="9C3FA5AFAA7B5C91" modified="2024-11-27" version="1">MVVPEKGGACSSGTLPPPPLSPRDLKRKWGFSGTAFRWFLMQGIILPTVRCTVANEILDAKVGWYDVKILFKFCWDFMTLRIGNGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PFZ3</accession>
    <name>A0AAV4PFZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_371951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004598">
        <property type="protein sequence ID" value="GIX96016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PFZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9460" checksum="A4344B38956C0CF1" modified="2024-11-27" version="1">MIREFIATLEQKQKGRVRGGERLRGNIPSIKEDGRESTAPRNYFLFTLRINKKKVERNTTLSPKMLLPQNFLPPLQTLLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PML5</accession>
    <name>A0AAV4PML5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_306601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004880">
        <property type="protein sequence ID" value="GIX98248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PML5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8436" checksum="95D321EB35206687" modified="2024-11-27" version="1">MSCVSSNGYGCSKGKIGHSKQDGVIDWQLFKVKEKLQKLKFTNGKLFSNSERPKRRMESPEDPRITFRAKSEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PP51</accession>
    <name>A0AAV4PP51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005012">
        <property type="protein sequence ID" value="GIX99172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PP51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10449" checksum="A55828F0836B4C4D" modified="2024-11-27" version="1">MDPFAFENLVDSSNSDPGLGKHPQRYPYLRPADIRPTVVPEKGKDRIRIPFLKQISALVFEVRGGQVVNNECYKEWKSSEITCKMGSSCLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUB5</accession>
    <name>A0AAV4PUB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_379511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005116">
        <property type="protein sequence ID" value="GIX99930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18882" checksum="BB231FCC84DA177D" modified="2024-11-27" version="1">MWHQHIEPETCGTSTSSPKHGTSTARNMWHLGIQPHRARNMWHQHIEPETCGTSTSNPKHVAPALIDPKHVAPAHRTLNMWHQHIEAETCGTSTSNPKHVAPAHRPETWYQHIEPETCGTSTLNPKHVAPASNPKHVAPAHRKHVAPAHRTRNMWHRASVTRHQTMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5Q6</accession>
    <name>A0AAV4Q5Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_760481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005618">
        <property type="protein sequence ID" value="GIY03741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12541" checksum="FE1AD8FEA5EE784A" modified="2024-11-27" version="1">MVLQGGMIQEKLTKSPVSAIRDIGHAVVQNGWFIEATLKSIGKTVFEENTVVVATRPFFVNHYDKEVYVAPDYFYSAQYGLVIHKSSAAKSCWDRKLRRIVATGLYEKVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q835</accession>
    <name>A0AAV4Q835_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MICAL-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Micall1</name>
        <name evidence="6" type="ORF">CEXT_485021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005702">
        <property type="protein sequence ID" value="GIY04367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q835"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000023">
        <property type="entry name" value="EH domain-binding protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050540">
        <property type="entry name" value="F-actin_Monoox_Mical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23167">
        <property type="entry name" value="CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23167:SF46">
        <property type="entry name" value="EPS15 HOMOLOGY DOMAIN CONTAINING PROTEIN-BINDING PROTEIN 1, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY04367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="16902" checksum="F71D1FE03A5C5237" modified="2024-11-27" version="1">MGEKRGMRALELWCRRVTDGYRNVRVNDMSSSWKDGLAFCALIHHFRPDLIDFESLAKENMLYNNALAFQVAEDRLGIPALLDAEDMVKYDEPDTLSIATYVSQFYQFFENGASHKLGIPAPKPVSNRVAPLPCSRPSATSIHTGPLNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAL5</accession>
    <name>A0AAV4QAL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005820">
        <property type="protein sequence ID" value="GIY05252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13511" checksum="825684F354C2A9FB" modified="2024-11-27" version="1">MTLALSDQVMLTKAPGEKMGIPLKTNIGKQGGDKECFLKEEDTAAVEDKKAQRVKDAVREHKVLMEASFCVYTASCGLNFGVMSSWNETLKQVSGVTHGKCHRYFRYCGNGSGEKPNVYDVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAS6</accession>
    <name>A0AAV4QAS6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="3 13">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RABGGTB</name>
        <name evidence="15" type="ORF">CEXT_136061</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterotrimer composed of RABGGTA, RABGGTB and CHM; within this trimer, RABGGTA and RABGGTB form the catalytic component B, while CHM (component A) mediates peptide substrate binding. The Rab GGTase dimer (RGGT) interacts with CHM (component A) prior to Rab protein binding; the association is stabilized by geranylgeranyl pyrophosphate (GGpp). The CHM:RGGT:Rab complex is destabilized by GGpp. Interaction of RABGGTB with prenylated PTP4A2 precludes its association with RABGGTA and inhibits enzyme activity. Interacts with CHODL. Interacts with non-phosphorylated form of RAB8A; phosphorylation of RAB8A at 'Thr-72' disrupts this interaction.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="3 13"/>
    <dbReference type="EMBL" id="BPLR01006053">
        <property type="protein sequence ID" value="GIY07148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000004">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5 13" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="14">
        <location>
            <begin position="19"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00062019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY07148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="36111" checksum="327322DDCE849455" modified="2024-11-27" version="1">MAALIKDVELTDKLPTKLFLEKHCDYISAYGKKKDDYEYCITEYLRLSGIYWGLTALDLMGQIDKLDKESVIDFIKKCQHKCGGFSSSIGHDPHILYTLSALQILTMYDALGVIDVEKTVSFIKSLQQEDGSFIGDKWGEVDTRFTFCCVASLALLNRLNEVNIDKAVEFVLSCMNFDGGFGCRPGSETHAGQIYCCLGILSITQQLHHVKADLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRIHWIDKDKLSRFILASQDEETGGFADRPGDMVDPFHTVFGLAGLSLLGDETIKEVNPVFCMSQDLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QF75</accession>
    <name>A0AAV4QF75_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LRRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_220595_1</name>
        <name evidence="7" type="ORF">CEXT_252361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006236">
        <property type="protein sequence ID" value="GIY08368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QF75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365:SF541">
        <property type="entry name" value="PROTEIN TOLL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365">
        <property type="entry name" value="TOLL-LIKE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="317"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY08368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="38664" checksum="C88527719EF8FFFE" modified="2024-11-27" version="1">MNSLTDLHLEGNRIATLGSKIHALTQLRILSISNNRIRTISTNQIPPRLMHLYLAGNPFSATARCYLLFLQFLNSSEELTIDEDLCTPSLNGNAHASPPARCPAPCRCSCSIDNFILVDCSSTGLTHLPPLFKRAGRDQEGLNLSNNKIQSLEEARLPSRMRFLFLDHNLMQKPPVFFLKSLKFLTRVTLSNNPWTCDCAALDFKKWVVSKSVLVLDVNETRCGPDMPNSTVVAERAIWLLPDLELCPDYTALYIYIVCGVLSKFVVGGGRRNNRLDTIQDEREGVALLTRSDLGQGEGHRQGQGVRRIHLLQLQRSRPRHSGANRGGRREGPGYQVVPSLQTLPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGS2</accession>
    <name>A0AAV4QGS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_793851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006123">
        <property type="protein sequence ID" value="GIY07551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="16785" checksum="697410BE06D7ED09" modified="2024-11-27" version="1">MVVEDVLEGLVFVGLQIGVQERAGHLHVPHYELLSVSIADGTEVVVVSDASCLAGHWSATEWISVATCVTFAVLDHELGSVPFLHAAVHHQGLPLADEVLGTLGGVRLEVLGVGAAVVVDGAGAVAVARPRSHDSFAVALVSAKGIFRRNCFPQYQESTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QU56</accession>
    <name>A0AAV4QU56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_476801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006777">
        <property type="protein sequence ID" value="GIY12359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QU56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8048" checksum="91CF82243D98538B" modified="2024-11-27" version="1">MDVMDGIDVGGWMLCLMLVGMDMGMDVMLDVGRMDVMLDVVMGWMLCWTLMGWILCWTLMGWMLCWTLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUC0</accession>
    <name>A0AAV4QUC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_341771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006723">
        <property type="protein sequence ID" value="GIY11916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8668" checksum="B0756750D6D575C7" modified="2024-11-27" version="1">MLNIVRQTPHDNDGSRSFILTADTKLDHCFRYPNVHQRFLHVELWECARFLSLKTIKLTGSNRLINTVDVITIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6M9</accession>
    <name>A0AAV4R6M9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">La-related protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LARP6</name>
        <name evidence="9" type="ORF">CEXT_270671</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007569">
        <property type="protein sequence ID" value="GIY17978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000158">
        <property type="entry name" value="La ribonucleoprotein domain family member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002344">
        <property type="entry name" value="Lupus_La"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024642">
        <property type="entry name" value="SUZ-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00302">
        <property type="entry name" value="LUPUSLA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51938">
        <property type="entry name" value="SUZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="7">
        <location>
            <begin position="62"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="159"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ-C" evidence="8">
        <location>
            <begin position="377"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY17978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="433" mass="47614" checksum="3AC4A6A17755C478" modified="2024-11-27" version="1">MSTEVISVEKIETTMPVSTKLIDVDDETSSCGNHSDGQNLSDSDPKDSGIECNVSEQKHVSDIPDDETAVAILKMVEYYLSDANILKDPFLLKHVRRNKEGYVSLKLLASFRKVRSLSRNWKAVAYSIQKSSLLALNSEGTKVKRLTPLPDYDETVTSRSVIVSGFSSDKPSVDSVSEMFSSCGDIALVRILRPGGSIPSDVKKFLSKNPDMQSKICALVEFEEHAAARKALESVQVPGISVISVAIKEKVTPESPKKTPPKDNQTENPKESPKKKKKNKKSIEKKSHDGETTAEQKRSRRSSSGSVSSQSSGYLSSSPTSNPFDSKFPRRHSYNPAIYNDPNSSFASLANRHFGSRDRLQKSGSESTEVLSPWRRRREQMMLSDSNLVSSTTSSTGSLLQSLPVRTIRMPKGPDGTNGFCTRAKTRLPSTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFP5</accession>
    <name>A0AAV4RFP5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="9">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">l(1)G0196</name>
        <name evidence="11" type="ORF">CEXT_61541</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
            <location evidence="9">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="9"/>
    <dbReference type="EMBL" id="BPLR01007938">
        <property type="protein sequence ID" value="GIY20803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000828">
        <property type="term" value="F:inositol hexakisphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="216"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="462"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY20803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="523" mass="57404" checksum="73ED38171CFC7621" modified="2024-11-27" version="1">MRADCQNGNLFPQHPPDRVKIFFSSPMYSHGVSSPERHVRTRLYFTSESHIHSLLTVLRYGGLLDLPEKCLLCSCLPEDSQDEQWRRAMEYVSAVSELNYMTQVVIMLYEDPTKDVCSEERFHVELHFSPGVVCCVQKNLPPGPGFRPQSRSGPKDRPSCPPSLCLTASGGYDCEKQTPRIDEEDDDLTLEDEMNCASDPDSPTLFEESEEKKLILGRNKASEPIPIQRASPKVSCSLPHKPCVAVRSGSDAHRPRSLDSESSKAAKPDKGSPHTQSLEDVSLNNKTAGQQREPFQHRHSIPNQLSSYLRMCSAADLPKVYGSANSLFSTAVISGSSSAPELKDAGPRRKGCLEPPSRELRPYALVVAVGEIHFERPVSASAQHPPPGDSAQRPLPAPAGLLPGAHDLLLLPRGPAVPGPPALPALAARRLTLRKRSLEWAPLVRVEQRALLPQFLHAGHLGPVARPGGRSPRLPQQPALPARPPVPQQQPLRVEDPRNLISSCVPARYSALILDIQFLNTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJL7</accession>
    <name>A0AAV4RJL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_289201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008160">
        <property type="protein sequence ID" value="GIY22508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11582" checksum="F28A9A1CF23E433D" modified="2024-11-27" version="1">MPQFGYIIENFKTKIFKLLPSVWKSLLQGPFNGKTQCSATVAVHLPLAAALGSLLSQHPLCSEDSIRLALLLINVLTELCWCRELLEVGSLGSSGSLPFHRMDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKN2</accession>
    <name>A0AAV4RKN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_3881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008021">
        <property type="protein sequence ID" value="GIY21451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12044" checksum="FB0BA479643B2F81" modified="2024-11-27" version="1">MSFIPCLFRAPKQDCEGKVPNPMQTLPLVSWTEPNTLLTSALQSKHGLKAALHASSMHALFGPFLNCHRMKWWPIADDSLCLPYKLHRRHLTMVKGSHIARPFVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSA5</accession>
    <name>A0AAV4RSA5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Epidermal cell surface receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_243931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Has antibacterial activity.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008262">
        <property type="protein sequence ID" value="GIY23327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00214">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00217">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57603">
        <property type="entry name" value="FnI-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0800">Toxin</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="40"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="125"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="6">
        <location>
            <begin position="296"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="386"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="854"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="401"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="857"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="871"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY23327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="931" mass="102857" checksum="C04493F1AE9FB223" modified="2024-11-27" version="1">MFGREPNESKSAKRPGGTFESPQESFGNPPLPTGSAELARPLSIEVFDVTSNSAKVRWGSSESELQPQALVFYSSLYRELHTQWNKVIGVKPVVLENLLPGKIYYVKVEEDGKQEISTFRTKDNVIGNMPKILVKQRSQTSLTVVWDDFRLPSYHSEYILEYKPSGDSNQNWTKVQAGTQTIVTVSQLKPNTPYDMKVAVWEDDKLELPSEVITAYTADGCIKDNRMYNVGEEYFLECDARCVCNGNNETSCTPRCNAPYVKIGSKEADPLCYEKPLPSDPCCVTIRCTESKFYEAQNKSGECPEIFEDSETESKCLSDCDHDGDCSGNLKCCLSSCGGAMFVNISTVDPMLSVSGKMACECDEGYEGNPHDFLTGCVLANATDGNVTEPQAGRSGFDINLDEKEHTDEMKEPSTTDMPEDKSNNSELKNELETESKESTKETVPTEAPFQLDLSPNANKTTTSLLDEKEKEDTNSSGTPSDEENFHLRRPQDSDPEELKPDTETAEEISGRDMNNQTIDVPIAFDGCEFNNVTYDRGAAFEDGCEARCTCEGRGHVSCVPRCTVLSAGGPTCKEVQDPDDHCCKIMVCSFPGSTEKEQVEDLPVKILSALAQNGTSIRVRLGLSMSKPPTMVGRDMFEAWYRESSDSDNDLSQWNKKLITQNELTEVQQGVFEFDINDLMPQTDYYIKVGKQSQGSPNFNMAEFSNTVNVKTFPAAVKSVFQGCFHHNQSYSLGEVFYQGCEHKCVCREKGFIECQDRCEVYIDTVGYEGCDWVPSEEDPCCTIPMCNNRRKIPIMPDGRVPFTGAPENMCVVDHSEMYRVGDIWESGDECKIKICRCTLLANGSTSIQCQSECPRSPPTPTSPPPAAPIPCSSSPTRPATAPTSSATTPPGVSCNPKDLSASTKARDMTWAKNSTMAALPCAIVDRTCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXW7</accession>
    <name>A0AAV4RXW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_44529_1</name>
        <name evidence="2" type="ORF">CEXT_501181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008570">
        <property type="protein sequence ID" value="GIY25726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043360505" evidence="1">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13505" checksum="D1984BAEC930D7EC" modified="2024-11-27" version="1">MVIFLAMFFNHLCMTLEVLAKNIHLCLNSPHFQSSLNFFPEHKDPFPNFHEGLFPTLPPEVKRHWQPLQPPSVPSPPQRPSVDEKFEGPLKNYDVVLGHTRYPKIFRFNEEKSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S131</accession>
    <name>A0AAV4S131_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_6924_1</name>
        <name evidence="1" type="ORF">CEXT_615101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008806">
        <property type="protein sequence ID" value="GIY27337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S131"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17063" checksum="69DF98F4D7236438" modified="2024-11-27" version="1">MFDDLKTPVIASNNHHLFDDWREVFFDNERADFDGYNCSSGHLRLEPAGDFYAFFTGDSFFITCIPDPSSGATRLTWQTPNGRDITHTREDFCSVIYVTKLILLSQREKNQISKYSLHFKETMTDRKISQTDFIGCDGQFNCVNRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1H4</accession>
    <name>A0AAV4S1H4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_807161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008682">
        <property type="protein sequence ID" value="GIY26426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1H4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9431" checksum="D876CE8AB3CBB4A1" modified="2024-11-27" version="1">MLQLPQLLSSLLSNHNRHDFSSLQHLKSIARWKTHQSFGELACLSHQHFSLGAGDRFIWSDSFFFPVVTFGFQCLLEVHNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S524</accession>
    <name>A0AAV4S524_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_625331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008831">
        <property type="protein sequence ID" value="GIY27575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S524"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9159" checksum="B33A4CE694B85B53" modified="2024-11-27" version="1" fragment="single">MKDPHSIRDLFSVWELDWGRRVHLNEKSLPPGASCTPPKASRSSPEAALRKVTASLSSSSSTSITVLFGLNGCCTYFITDSLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S786</accession>
    <name>A0AAV4S786_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_373451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009016">
        <property type="protein sequence ID" value="GIY29041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S786"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12194" checksum="BB24425BB774F3FA" modified="2024-11-27" version="1">MSCPEIFSGILDVTELMNTMPSGTVKSVGSRWNGWSARSPGGLSQKQQFSVALEGGRFVIALIISHSSDLLPAHPTGWDCSRHPSRGYWFTCHSCGGGAIPQICTCGMEMMNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7B9</accession>
    <name>A0AAV4S7B9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_149801_1</name>
        <name evidence="3" type="ORF">CEXT_251571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009183">
        <property type="protein sequence ID" value="GIY30163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7B9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.60">
        <property type="entry name" value="Spidroin, repetitive domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043070">
        <property type="entry name" value="Spidroin_repeat"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043461609" evidence="2">
        <location>
            <begin position="24"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY30163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="883" mass="96166" checksum="BAA5A2E015B23A18" modified="2024-11-27" version="1">MNCIKCCAVFFVLISTLLVLSSASSHSKLQTAQRYENCVVRNLSELSIFDEEDRMRMNKLALETGVRMYKLQLDPENDENARTMLRLFAAALANVVADTDSSNRHDREKACIMAFESCSEALLEKDGAELVKELRKIFSSMERVISLLDAAPDNKTPSASQKQEKHLEESTEHTCSKEEEEEVKNRSKRAYVPLFGLRSSNVQFRSNQSLESIIADILLKSTSFNNYFKAGISQPDAIYYSRAMVGAGLAGYRYDLIDEALNLVTNEVTSLGEFAGPRDYAYAIARSIATVISNRNMFANGFDIGNASVFKLDSLLEPVSSFSVPSFGASASSSSWASAGGGQTGAFSFAQFNPGFIEPSFSTFNTQNSKDQFQNRMSDLLSQSNIISEAFCSGSYPNLFILFNSALSGFGFLVSSTVANIASNSLSMLPTNAACTQYADVISEVITNVLQNNGLLETADAQEIVNNIEININYNPSERAENLGKQPFSGFSDFQLNPSFSDTPANFNPEYPVVENPDSSYVPSFQFDEPQFPFNPTEFKDANVQSQSGIDASAIEVSDKQDFSIPATSGSDGIDSTIQTSTLLGDSKLSNTSIAVSGLLSNATKPLDKLNQTRVSLDVSTGVLLEPVSVISEDAPVEKSKPEEANVKIEETPAISAEINVKQPEVTTPTPIITDGPTTINKLEITTPAPQVAAKDDESKVSDVILDDIYSSLRELNMTSEDVKPQVDAPKEDKTVKVIQDGDLTITKPPEPVADTKVLVSTVSPPTLNDKPVLEAELNIEVKASAEPSTAVSESPDADDKKESENNPLEEDLIKEFANIIATVTNESIGLIRSRDFKIDDLCSKLNTLAPLVDLPPLEYCEEMAIIDYILNVLSAVNYIYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8Z1</accession>
    <name>A0AAV4S8Z1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_573511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009270">
        <property type="protein sequence ID" value="GIY30718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8Z1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16564" checksum="3ED941640387F1D1" modified="2024-11-27" version="1">MAGDGLMGGNCGVLLERRSICQWWVWVAEEKCLLGERLMAVKGDGDYLCFEVIISYNIKSTISTTSTNRTQERNNKNERTWKQERNPKVPNCREKWSDFYPKILYFRRDFGTLPLIPSPPKFPLSDFLLLFKPSGLKSLHSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLE0</accession>
    <name>A0AAV4SLE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_3581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009815">
        <property type="protein sequence ID" value="GIY34834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8078" checksum="64E3A02AE558CC72" modified="2024-11-27" version="1">MAYLTKDMPNQTLFNKHLDEVLASMGPSRQSLLSWQGGGSLTIKAFHAFINRGFHPSALLEDYLRTLKAGGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWB9</accession>
    <name>A0AAV4SWB9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_299191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010342">
        <property type="protein sequence ID" value="GIY38668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWB9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12995" checksum="33E80051450EF9C9" modified="2024-11-27" version="1" fragment="single">MCVEECENCPSVRELLPFTEVIADVIVECERQVGKSITSMSATARPVRMALVGDTMFLRVKTMIFRTLAVIPKRQTMKLRKRRSLRNSAHLCALQRQPEMEIDLDRKTEAWAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZE6</accession>
    <name>A0AAV4SZE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FERM, ARHGEF and pleckstrin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Farp1</name>
        <name evidence="5" type="ORF">CEXT_604101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010218">
        <property type="protein sequence ID" value="GIY37797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070161">
        <property type="term" value="C:anchoring junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17098">
        <property type="entry name" value="FERM_F1_FARP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000040">
        <property type="entry name" value="FERM, RhoGEF and pleckstrin domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014847">
        <property type="entry name" value="FA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019747">
        <property type="entry name" value="FERM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018979">
        <property type="entry name" value="FERM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018980">
        <property type="entry name" value="FERM_PH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051835">
        <property type="entry name" value="RAC1-GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45858">
        <property type="entry name" value="FERM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45858:SF5">
        <property type="entry name" value="MOESIN_EZRIN_RADIXIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08736">
        <property type="entry name" value="FA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09380">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09379">
        <property type="entry name" value="FERM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01195">
        <property type="entry name" value="FA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01196">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00660">
        <property type="entry name" value="FERM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0965">Cell junction</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="4">
        <location>
            <begin position="23"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="254"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY37797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="549" mass="62353" checksum="E0EC1C021CCFEF63" modified="2024-11-27" version="1">MSSPTSDSQETKVASSHRSRKFINVTVYFLDDSSHVFQLQAKSLGQALFEKVCKFINVLEVDYFGLEFEDDKKIKCWLDALKPLCSQVTTSFPTMYFCVKFYTPDPVQLEDEFTRYLFGLQVKKKKILQMITGQTPAEADLNLLETARRCELYGVKMTAAKDHEGVPLNLAVAHLGLLQRHCEFFFEGRNECKNFWKKCIENHTFFRCTDAKQGMRQKPKIFSRGSSFRYSGRTQKQVSEFVRENCFKRQPFQRSTSLRTPSSPSRSIGTSISPQPLLPSSTTPSVKTALGCQTPLSQVQYPPDGDYGHEYYSQDTDDNISHDSYNVLDKESATKTNTECLSTNIANTSNSKDQDMESSATKNDGGKSNDEYEDDDYRRKSRRHHRPETLCKAYPRTVDFVYVNQLPAVGSFSYRDDSVELKSPGKLKLEMLRQKLKDEDFSSCIVNGSDFRARSKSQPLLPLGVDLLNDLVHVNNLSQKPSCSRDFNHKESAMKVIADNLDVKKNKPSIIQNADVLPSTSNQVTSIPPDCIPKKKEPEITTERLHLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDH4</accession>
    <name>A0AAV4TDH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_170781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010911">
        <property type="protein sequence ID" value="GIY42947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7465" checksum="76206737980E096A" modified="2024-11-27" version="1">MMEMKAVIANILRRFRVTSLDPRDKVNVYPNLVLRNVSPFATASSSNCFRVVVIEVRNDGNEGCYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TF41</accession>
    <name>A0AAV4TF41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_212801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011042">
        <property type="protein sequence ID" value="GIY43831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TF41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12477" checksum="7698DA3E7D4D8CEB" modified="2024-11-27" version="1">MCQLRRVKASMLNHSPRCPGTVEIVRKLLRAVCCRWCRPLCWSEYLAHHVAMCPEELLECLRLHSKILSYSRKGYSSYELRWLSSFNSRFWGGIPDDTEWFPGAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFF1</accession>
    <name>A0AAV4TFF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_555971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011064">
        <property type="protein sequence ID" value="GIY43944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10393" checksum="A4D0A342B06E9157" modified="2024-11-27" version="1">MRTEVSQQLVHHSDDDRNSQFAPRGFIVYGRHHRFFASLSHTTWQLALALTNYQIIAICIMRRGRRLNFKTGFRFALLLCAPFNAVEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJE0</accession>
    <name>A0AAV4TJE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_381381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011210">
        <property type="protein sequence ID" value="GIY44907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13627" checksum="711717C17C59618E" modified="2024-11-27" version="1">MSDAHQIRLNSLNSPDVIITCADECISRGLVLSGTHMLELTDALSLCRTTYSGMGNSSSGRIPRGFEPYSSESKGIVWFSVFSRLSAWRIRTGSGSAFVFFADRILIILLLQWATYNEAGVSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TW65</accession>
    <name>A0AAV4TW65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_518471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011972">
        <property type="protein sequence ID" value="GIY50359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TW65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9924" checksum="CC3D872920A80C99" modified="2024-11-27" version="1">MNGYFYENRDRNNEITRQNVSDERGKATNRIIPKGSQKQYKIHKNNYFEGCHLPVRLLDFLLKKCNAGSNIDPSKTSVQFALLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYT3</accession>
    <name>A0AAV4TYT3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SmB</name>
        <name evidence="13" type="ORF">CEXT_40541</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011964">
        <property type="protein sequence ID" value="GIY50327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="4"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY50327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12233" checksum="6B174D0EFC526884" modified="2024-11-27" version="1">MTVGRSNQILQFINHRMRIILRDSRTFIGTLSAYDHHMNLVLTDCTEYRKYKPHRKAEIEGKKVIGTAIFRGENITSIILENPPKSSSRSESESGSRYGGGNSYSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8A9</accession>
    <name>A0AAV4U8A9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_728851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012463">
        <property type="protein sequence ID" value="GIY54057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8A9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9503" checksum="611E35F9BA092247" modified="2024-11-27" version="1">MCKSSPEPLVEQSVSNYESTVPLEHHNSFRCEIVNVQSIPVKNSVTEEQNKQRADRKIQRIDVNNFLREKRKISDDFSKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UC62</accession>
    <name>A0AAV4UC62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_741401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012637">
        <property type="protein sequence ID" value="GIY55390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UC62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11608" checksum="F54AFD21FF367E7C" modified="2024-11-27" version="1">MLESVHGVVYNINNSKIFRVIISIRGISHSFQNVLWRSLPPPLRCSTETKKFEFLVAPERRWRAPIFFVRYGVKHSNGGDFHCAIPLCFACDEFPRKLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULQ7</accession>
    <name>A0AAV4ULQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_444721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013083">
        <property type="protein sequence ID" value="GIY58625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10893" checksum="8A4A6F01DBC414BA" modified="2024-11-27" version="1">MSNTTLKELITATTKSFQITVGCAVDPEAKALLRQRKMIFSSKYSPELRRAGNLHLWKGSGVKIAVRKRVCQPTAWDDHEYYSSVFMAIQKNVNKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUR3</accession>
    <name>A0AAV4UUR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_515901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013471">
        <property type="protein sequence ID" value="GIY61469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="391" mass="44718" checksum="5EE924FEE2CDE7FE" modified="2024-11-27" version="1">MFKIQVQPDLKLWVYRKMKEPYYTQLTNACIIGRLCGIDSFSTKILFFHKKVHPRPGKQPHYSKYQSSKNYQITVNAFRGKIWGPNINPHMSYKTNIDQPRQVTACRRIVVIIVVTVDKYFLAAERDAIVHEKLIISMGRLSGFIKTVTLAPKLNSADQGICNDIKLNPHHHKQHWPPTGKEISEKENLRPELSGKGSLLMFFIGREQIRFFLSLSRPEPHFVDKKIFRVHKHLCYFGVEWDSEVFGSPLISVVTGFSHGELQRLPEDHRSKGVQSISLLKAGYFTWLLPAELDSLVAAHGLLTLETRAGRLLSWLGRRQQVEPFGTEVAMQMELFPLENILWGLSTTSADFAIQAIPSRCWFAIWCLLKGVWRQLLLTALGAQCDLPEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWQ1</accession>
    <name>A0AAV4UWQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_667341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013572">
        <property type="protein sequence ID" value="GIY62073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12961" checksum="5FB7B8CCA08B611E" modified="2024-11-27" version="1">MKRAFLLPPPPFARSCLGPPTPSTPAFPPVKIGLYECERRQEDKAPKKERRMKKKKRKKRRKKKIERKVSKIQNLEGKRGNKDDDAAASLSIMHKAKQRAPVGLLKDACMQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY41</accession>
    <name>A0AAV4UY41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_510021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013644">
        <property type="protein sequence ID" value="GIY62641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17878" checksum="530140459F35F35F" modified="2024-11-27" version="1">MCPWQMQFSDISAKCDHRATHPSGYHRSNLKRTMHINDRNYKSQDRCGTVIAVSAICYVETMTKGFFSLVMSYKKFEDGLFTCHTITKTCTINSPMQKLFDKEVWNAEAYAKYSGQVVLACFDPDTFSLRRVSLLRSLQTGIIRFPDLECKRSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V302</accession>
    <name>A0AAV4V302_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_317791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013845">
        <property type="protein sequence ID" value="GIY64218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V302"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11450" checksum="4D70747C33B235CF" modified="2024-11-27" version="1">MSAIAHRHHTIFQSSHALFVIILFQNTTPRRSPRIPCSCLKYPKKSLSGKQSINGSHYSSPTRGQHQFTGSKSGEQRSKWKMGHLNFLEIFLGNAYFESDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V424</accession>
    <name>A0AAV4V424_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">N-alpha-acetyltransferase 20</fullName>
            <ecNumber evidence="5">2.3.1.254</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Methionine N-acetyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">N-acetyltransferase 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">N-terminal acetyltransferase B complex catalytic subunit NAA20</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">N-terminal acetyltransferase B complex catalytic subunit NAT5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">NatB catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">naa20</name>
        <name evidence="18" type="ORF">CEXT_758461</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N-terminal L-methionyl-L-asparaginyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-asparaginyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50484"/>
            <dbReference type="Rhea" id="RHEA-COMP:12694"/>
            <dbReference type="Rhea" id="RHEA-COMP:12695"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133356"/>
            <dbReference type="ChEBI" id="CHEBI:133358"/>
            <dbReference type="EC" id="2.3.1.254"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N-terminal L-methionyl-L-aspartyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50480"/>
            <dbReference type="Rhea" id="RHEA-COMP:12692"/>
            <dbReference type="Rhea" id="RHEA-COMP:12693"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133045"/>
            <dbReference type="ChEBI" id="CHEBI:133063"/>
            <dbReference type="EC" id="2.3.1.254"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N-terminal L-methionyl-L-glutaminyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-glutaminyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50492"/>
            <dbReference type="Rhea" id="RHEA-COMP:12698"/>
            <dbReference type="Rhea" id="RHEA-COMP:12699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133361"/>
            <dbReference type="ChEBI" id="CHEBI:133362"/>
            <dbReference type="EC" id="2.3.1.254"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N-terminal L-methionyl-L-glutamyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50488"/>
            <dbReference type="Rhea" id="RHEA-COMP:12696"/>
            <dbReference type="Rhea" id="RHEA-COMP:12697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:133359"/>
            <dbReference type="ChEBI" id="CHEBI:133360"/>
            <dbReference type="EC" id="2.3.1.254"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the N-terminal acetyltransferase B (NatB) complex which is composed of NAA20 and NAA25.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.254" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01013905">
        <property type="protein sequence ID" value="GIY64649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V424"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120518">
        <property type="term" value="F:protein N-terminal-methionine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="17">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY64649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16630" checksum="396BA0D6B04A080D" modified="2024-11-27" version="1">MTTIRPFTCEDLFRYNNVNLDPLTETYGLSFYLQYLAHWPEYFQVAEAPNGDIMGYIMGKAEGHSENWHGHVTALTVAPEYRRLGLAATLMNGLEDISEKKKSIFCRFVCDPDEDAFDMRKALSRDINKKSVIPLAHPVRPEDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4M4</accession>
    <name>A0AAV4V4M4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_463411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013914">
        <property type="protein sequence ID" value="GIY64713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10638" checksum="720118DE013CBF4B" modified="2024-11-27" version="1">MPKTTALMVILVSFEMMWNSFLANRAHILACVFYLFVRYCTHSIDVVPKYKDMKIPLHYNPAMKSPDAKKWQSAMQEEIMSSKNVCEFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6B9</accession>
    <name>A0AAV4V6B9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_315711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014004">
        <property type="protein sequence ID" value="GIY65563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6B9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14718" checksum="10AA90285D874277" modified="2024-11-27" version="1">MPNALQRSPSSYKIANIDVPQVPIGVYGASALKHFHQTSMVPPIGPLKKRGRPPTKTGQTVSTINAGSATRCSRRNQRGGGNMSGYDRGSTYAHCKPCFHCINDILSKPRRVFYFSAPKTRNKNTEGMVKNIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8E0</accession>
    <name>A0AAV4V8E0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein beta chain, ciliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DYHC_1</name>
        <name evidence="2" type="ORF">CEXT_440431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014027">
        <property type="protein sequence ID" value="GIY65790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8E0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12365" checksum="962944F46EC39E14" modified="2024-11-27" version="1">MDLLISKGHPIMLVGSSGCGKTSVIRSTLDALDQESTYLIVNVPFNFYTSSATVQRHGAAPREEVGKNFGPPGRRRSSTSSMISTYLRWICTGHVNLIPSFGSIWTTATGTIATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V929</accession>
    <name>A0AAV4V929_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_24631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014137">
        <property type="protein sequence ID" value="GIY66627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V929"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11384" checksum="352AB478011414E0" modified="2024-11-27" version="1">MALSKRIDIKTYPLSGAKGKCYGYFKKWWYLKIYSGDDEEQFIKEYSSCSIMITNGQKFDCAVLIRREKFSISIHAKGLENSRGIRQRIRNKRFESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJU9</accession>
    <name>A0AAV4VJU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_244521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014639">
        <property type="protein sequence ID" value="GIY70235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="22478" checksum="C3B15EE9C14BD6EA" modified="2024-11-27" version="1">MEFLSPIRFSSALRRIVRFDKAINPFWSPQRIKEKWKMNYNTDVKSGDYKKGGGEEEGLENQEKSIVWNDDTKISRLHRRRRRRKMARNHDNEQQRRSEFEESSHFKPITFTLLLPNSPPTPRKTLKRPKLNAVGKDESLPMSRSFIQLPMSPDGGAPRALSLFKRKGKGKGRQKRTTADRLRRFIERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNS1</accession>
    <name>A0AAV4VNS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_71911</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014884">
        <property type="protein sequence ID" value="GIY72022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050328">
        <property type="entry name" value="Dev_Immune_Receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373:SF370">
        <property type="entry name" value="FISH-LIPS, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373">
        <property type="entry name" value="SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043697106" evidence="4">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY72022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="33949" checksum="C8D3232558C5F5D6" modified="2024-11-27" version="1">MSILCTVILFLCVSLTQAQCPSDGRILEPCHCTSTREGGDELSCFGPIGLVNLTTILRNKMCGRTLDRFKLTLSDIEYLPSNLFFKIIVRDIQISFTTISHFTKGGTSAFFGLESHLLSLSMRRGRLVDNLQWEKIGDLHALTYLDLSFNNLTKIPQQWFHHPPPNLLSLILKGNKIRTLESGALKHMHELIELDLSDNQISTITRDVFPFPGNALIFLRLNDNELRELPLDLFDEMMGLRRIYMDNNQLEDIPHNLWGPIWGDLEILDLSGNLLDCNRSSVEWIKEVLPPLHLYGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRB4</accession>
    <name>A0AAV4VRB4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_93096_1</name>
        <name evidence="2" type="ORF">CEXT_275331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014988">
        <property type="protein sequence ID" value="GIY72746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118:SF12">
        <property type="entry name" value="CYCLASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY72746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="27487" checksum="A640B069B11C1CD2" modified="2024-11-27" version="1">MHMIDMTYNFDETAQYSPIAEGFKINVVMNGTNENGVWIQLEEYSSYIHVGTHMDAPAHFSKGGQTVEQIPVDRLIAPAAVIDITAKAAAEPDAEATIEDLLHWESVTGQTLNETIVVLKSGWGKKWSDRAAFLGTPENDASKFHFPGLDPDAAAWLVKSRNIYGIATETLSFDKGSSKTYASHQILLGNNIFALENIANADKIPIYGAKLYVMPMKIGKASGSPTRIIATFPKITYDHSSASNEQNCFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRR6</accession>
    <name>A0AAV4VRR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_118771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015015">
        <property type="protein sequence ID" value="GIY72972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22044" checksum="3497A4002739E18E" modified="2024-11-27" version="1">MLHHFEKKSLTNLDPAINKECTFSTIKIPEIIFESNNLDVPKSNEFTDKTKIMQAKPFMDSEYDSCTSISSNKSCNSKSSDDVFHSCESLSEILDSSSELDESKNSLMQSNQSLCEVNSSVDLNSSITENVDYPNEAKIAISNVSIKSQQQYVTLSFPVNLVPKKVLKNIKLHAMIKVGLIPHVLPHLSHVLYMDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUW0</accession>
    <name>A0AAV4VUW0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cuticle protein 16.8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_228291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015034">
        <property type="protein sequence ID" value="GIY73110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF235">
        <property type="entry name" value="CUTICULAR PROTEIN 73D, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY73110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="32600" checksum="EE8A3D0E648D1EB1" modified="2024-11-27" version="1">MTNWLEFYVLSFCSPFVAGPRKVGLLPVGPREVFYFLPTIHRRPMKASPYPPPGDALSRGYRLPEDLMHINSCRFYCSLLYSSLLLASIDEHHEHHHPQPYKFGYQIKDHHGSQHRQEHGDGHGNVQGSYGFTDHKGIYREVHYVADHHGFRATVKTNEPGTANQNPANVQLHSNAQHGLEHYGYHHHHHQQHHGHRQGYNNQQYPILPLQHHDHEQVYHQQHHDDQQVYHQQKHYQDHPYEQNQKHQQQYHHEHQQHQPEHEYHDENRPHGGHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVJ4</accession>
    <name>A0AAV4VVJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_746131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015222">
        <property type="protein sequence ID" value="GIY74470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13935" checksum="0A83D549DC81059E" modified="2024-11-27" version="1">MIKAVQKHIPVLFGLSADGSFSLIFGRQQDINNGRLICVRNFLEEQFSAGNDSVSKFNMQELNNKHIKSCRQTIPKSPYPGSFHQPAIKSLQDGIESLVQMWVEISEVIAATPIAPDRSLVHNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3Q6</accession>
    <name>A0AAV4W3Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_805381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015587">
        <property type="protein sequence ID" value="GIY77186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8390" checksum="C4CD955DEE0E51A7" modified="2024-11-27" version="1">MLQLKLGCFASSMFLDIDLDVQFIEAHHTVEATSPVGCPLTSAWKEYQGWNDKLCMEPFHTSSGEAFHTSVPTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5L6</accession>
    <name>A0AAV4W5L6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_306151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015636">
        <property type="protein sequence ID" value="GIY77499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14911" checksum="B8897F01A7B1DF1D" modified="2024-11-27" version="1">MSKGFAELTNYVTQSSRRSLFPHHANINSFLPAPLLTRATDYGCHKTPMGIVQHTQYYIIHFIFLLYNPPEWLLKRKPIPNTSAYGSRERAKRRLSARRPFHLSQGAPAGGSKRNSIKLTLTRPRSTFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8R7</accession>
    <name>A0AAV4W8R7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_628461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015794">
        <property type="protein sequence ID" value="GIY78773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8R7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12887" checksum="347F0AD40F447EE7" modified="2024-11-27" version="1">MPFGSSPCISSTKCLTETQAKNLWSASDMGIFAGCSGFEASEGCKFLIPYCGSDDCCKCIDLYSFFLQMVGLEKENLKLQDYMDSGFDHSTGEIFQQLTSRHSLFFDASQEKALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCU0</accession>
    <name>A0AAV4WCU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_234691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015849">
        <property type="protein sequence ID" value="GIY79125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11359" checksum="503FA8F1B829683B" modified="2024-11-27" version="1">MSRICKRFKDTGNGHRQSGQGRKHVTIDFQDHYLATIAKRKRQLQLFQIAREFPAATGTRLYMFTVNDRFIKEGSMQEKTLCKSLICIPLTPAAKCVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJN9</accession>
    <name>A0AAV4WJN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ras-related C3 botulinum toxin substrate 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RAC1</name>
        <name evidence="7" type="ORF">CEXT_548441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016334">
        <property type="protein sequence ID" value="GIY83091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046843">
        <property type="term" value="P:dorsal appendage formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007254">
        <property type="term" value="P:JNK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030032">
        <property type="term" value="P:lamellipodium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035011">
        <property type="term" value="P:melanotic encapsulation of foreign target"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008078">
        <property type="term" value="P:mesodermal cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007520">
        <property type="term" value="P:myoblast fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006911">
        <property type="term" value="P:phagocytosis, engulfment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090303">
        <property type="term" value="P:positive regulation of wound healing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903391">
        <property type="term" value="P:regulation of adherens junction organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050770">
        <property type="term" value="P:regulation of axonogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007426">
        <property type="term" value="P:tracheal outgrowth, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01871">
        <property type="entry name" value="Rac1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000088">
        <property type="entry name" value="Ras-related C3 botulinum toxin substrate 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0581">Phagocytosis</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY83091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="21514" checksum="A2E7D95BC1912ABB" modified="2024-11-27" version="1">MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVSHHCPNTPIILVGTKLDLREDKETIEKLKERKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKNVFDEAIRAVLCPQPKPKKRRHCRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMB5</accession>
    <name>A0AAV4WMB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_176391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016384">
        <property type="protein sequence ID" value="GIY83424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY83424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9895" checksum="A476362BBB2A9A46" modified="2024-11-27" version="1">MKISNKAEFPPHLTPATSFSPRRDPSNPQFCQPPSYPQTSLLIKDGEKSQVCAPERKERSPDKISFISSSQSSGDLQDLGLDCSKRKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMJ4</accession>
    <name>A0AAV4WMJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_588161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016399">
        <property type="protein sequence ID" value="GIY83548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11876" checksum="C22423C0E3882C4B" modified="2024-11-27" version="1">MTSGGRDTLGHSCSLQEISKSVPFPTILFAAEYLMSVWESPLQEFRFVCSHYSSSSSRMKIWAGGSSGLYFFSYASLKSSTAFVTFSKSLGKIKFFILTIFRMTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXW6</accession>
    <name>A0AAV4WXW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_640481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016922">
        <property type="protein sequence ID" value="GIY87311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9093" checksum="2C9EB40C394F8CCE" modified="2024-11-27" version="1" fragment="single">MTRNSWIQRVRLTSLIFPERLPNLSDEERCARITTAIKKDIAQNLYGAYAATLTGHSPDDDDLKKITILHDDLQHAMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X117</accession>
    <name>A0AAV4X117_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Antistasin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_472421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017071">
        <property type="protein sequence ID" value="GIY88496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X117"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043517603" description="Antistasin-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11734" checksum="3A5998C3D26400B3" modified="2024-11-27" version="1">MKTLFVLLIVGAALALANASDCDNGNCPPMIQCDLPRCEKPCRMNYNTEPCPSCDCPDDCDDEKYPPIIQCDLPRCEKPCRMNYNTEPCPSCDCPMIVTMKNIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2S9</accession>
    <name>A0AAV4X2S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_556231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017022">
        <property type="protein sequence ID" value="GIY88084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13360" checksum="8C6BE817D463FC9B" modified="2024-11-27" version="1">MKDVWAVLIAEFSVSTKGALMRKPYILVSTIRKKLGGRLLPWAVEDPAETNDSGTSSETMKLKKTSEAAFEKGQGHPSCKKKGKKKLTRKTKNASSPLPLYSGNTAVWMHIYFNSETNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9T0</accession>
    <name>A0AAV4X9T0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_349381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017344">
        <property type="protein sequence ID" value="GIY90721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9T0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8254" checksum="11B31B90382BDD38" modified="2024-11-27" version="1">MCEHDKLHIRNPTVDWTSTACYATLDMHHHHIPSQFVWQNSVDRAHTLTLDRLLVDRPYKVLFFPGDLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XA87</accession>
    <name>A0AAV4XA87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_374411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017358">
        <property type="protein sequence ID" value="GIY90885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XA87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9110" checksum="7D7932C9A021CD7F" modified="2024-11-27" version="1">MGDVRSGIGDQNTINASASCVLSQASWSINEPTFCWVTNYIPLPAGQCMETVHSAPLSRNAHSNITVPLGSQIVEPVLWNLWNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAW0</accession>
    <name>A0AAV4XAW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000056">
        <property type="protein sequence ID" value="GIY91813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16429" checksum="EAD458318E3D1630" modified="2024-11-27" version="1">MLKRVQNKYEPALKIGPNIPADHSHSRSSVHLSCTASLTTNGSTDCSTLLISSKHAIWSRITSEFGGTTCNRNCIELPRMDYVKRKPYRKVITSFWSCFIKSPNPHNYQTWKTYEFDNLEAVKSDRDKSCVSTSWIALELVLLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBH7</accession>
    <name>A0AAV4XBH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_767321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000076">
        <property type="protein sequence ID" value="GIY91967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9657" checksum="089F70B3EC6EFDE9" modified="2024-11-27" version="1">MKGFSVKDNPKIYSLKKPMHTAAGLFAGSQSSTNCAFCNEKNHESKNCKLALNLDLQEKNNFAGQEEMLLSMFQDRTHGKAVYKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM07</accession>
    <name>A0AAV4XM07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_659321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000567">
        <property type="protein sequence ID" value="GIY95724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11585" checksum="76B9845C62AF3029" modified="2024-11-27" version="1">MRAISIFTFASRKKKKDCVLQDKQETNSCTVALTFSHASNDANRPRLATNRYLLRHRPCVLMEDFCTHRRRNGLGWLVRLLFAKNPVEELLGSHVKQLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMG3</accession>
    <name>A0AAV4XMG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_169021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018027">
        <property type="protein sequence ID" value="GIY96280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9518" checksum="905BBBCF0B7427C2" modified="2024-11-27" version="1" fragment="single">AAVVTSEIACCAQTVLNVMSLVVNGNFNQFPTFSSNIPNGNKSLKPSLVERNGRSIGVCIKRTNSPSMYRSSFSHVAYEYEDIQSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y402</accession>
    <name>A0AAV4Y402_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_140101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018754">
        <property type="protein sequence ID" value="GIZ02057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y402"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9082" checksum="5AED016F908691D1" modified="2024-11-27" version="1">MSSMGVYTPDSSTNSGYNSVEIDVCQLGLESPTSVCSSEITQQNSVEARSSPQSYPDCAQLSNNPSPYCTNLSISNSVLIIIAVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y455</accession>
    <name>A0AAV4Y455_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_167561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018750">
        <property type="protein sequence ID" value="GIZ02022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y455"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="24566" checksum="C440BCD1392B88FC" modified="2024-11-27" version="1">MGPFERMISRQCSTDLTDCQFTAHDCRENKFIFHRGHAVHWPLQRLTNRGYVQTIIKLKEVKGYLSQLNTVDPHHGWFLSIDVLGYRQQKFLKKYCEFNSVVDLYRECPHFSMLIYMEAPWAHVPISPRFHKGFHHEKNAKCSRYMVWYFEGLYTTNKGNWPGKWNKNHSQCFGSHCNGFYTCTIDFWFHLRCSVFTNLSSQIHIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5P6</accession>
    <name>A0AAV4Y5P6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_19461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001504">
        <property type="protein sequence ID" value="GIZ02776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5P6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12536" checksum="DA02F9A7116D1805" modified="2024-11-27" version="1">MDVKMEEKSRIIGERMYYNAVKYNPHTISTVQCLYQRGVFSRDGGGIIFRLVRQTIKVEESASSRKAKKELIDLLGLPFRITLARAIKGDRCDAMRFYPFYCVKYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5U5</accession>
    <name>A0AAV4Y5U5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inactive selenide, water dikinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SelD</name>
        <name evidence="8" type="ORF">CEXT_12051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001482">
        <property type="protein sequence ID" value="GIZ02622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000006">
        <property type="entry name" value="Selenide water dikinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000010">
        <property type="entry name" value="Selenide, water dikinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256:SF0">
        <property type="entry name" value="INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="SELENIDE, WATER DIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036407">
        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0711">Selenium</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PurM-like N-terminal" evidence="6">
        <location>
            <begin position="65"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="7">
        <location>
            <begin position="190"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIZ02622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="379" mass="41922" checksum="AC644A82F7FC61FA" modified="2024-11-27" version="1">MEDPNQQCLSAAVQLEVSNTPWGYRFPQETLHKLLEGLDQDGFIHDVEEQAHFMQMPITRIGIGMDCSVTPLRHGGLSLVQTTDFFYPLCDDPYLMGRITCANVLSDLYAMGVTECDNMLMLLAVSSKMTVAERDVVIPIIMRGFKDCAYEAGTRITGGQTIVNPWLTIGGVATTVCQQNEFIVPDNAVVGDVLVLTKPLGTQVAVSAYQWLDVPERWNRIKLVITQSDVQKAYQRAVDVMSRLNRIGSRLMHKYNAHGATDVTGFGLLGHAENLAKIQKNEVSFVIHNLPVIAKMAAVAKACGNTFQLLQGRSVETSGGLLICLPREQAAAYCKDIEKQEGFQAWIIGIVEKGDRTARIIDRPRVIEVPAKDKDGELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD31</accession>
    <name>A0AAV4YD31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Solute carrier family 25 member 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">slc25a39_2</name>
        <name evidence="13" type="ORF">CEXT_393541</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019280">
        <property type="protein sequence ID" value="GIZ05312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIZ05312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8043" checksum="441454F24EA86108" modified="2024-11-27" version="1">MLFVKISRYEGVTSLWSGLLPTLLISVPSTVIYFTAYDQLREAFSSHFVPPLGAVSVPFLSGTTAGKKFIFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD38</accession>
    <name>A0AAV4YD38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_92881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019307">
        <property type="protein sequence ID" value="GIZ05386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8515" checksum="A61F57060777F0B0" modified="2024-11-27" version="1">MDTICHRAKALKGIASETFYDNLPLISSFSMNSCSDGVTVTINYPDSFKEQNGPGSISFPFWLCLVINYQRKSDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7T3</accession>
    <name>A0AAV4M7T3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MAGUK p55 subfamily member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MPP6</name>
        <name evidence="8" type="ORF">CEXT_214861</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAGUK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001913">
        <property type="protein sequence ID" value="GIX67938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7T3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030054">
        <property type="term" value="C:cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10832">
        <property type="entry name" value="PDZ_MPP6-MPP2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11862">
        <property type="entry name" value="SH3_MPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000069">
        <property type="entry name" value="MAGUK p55 subfamily member 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.650">
        <property type="entry name" value="L27 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014775">
        <property type="entry name" value="L27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004172">
        <property type="entry name" value="L27_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036892">
        <property type="entry name" value="L27_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050716">
        <property type="entry name" value="MAGUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23122">
        <property type="entry name" value="MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02828">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00569">
        <property type="entry name" value="L27"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101288">
        <property type="entry name" value="L27 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51022">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="L27" evidence="7">
        <location>
            <begin position="81"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="164"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="248"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate kinase-like" evidence="5">
        <location>
            <begin position="373"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX67938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="593" mass="67519" checksum="C93C0A2CD8C05E04" modified="2024-11-27" version="1">MVICGSKHDDEGRELLKSMEKINEQKQGTAFQHVRENIEDLNGRVGARDTDIIFLKGLMESPVVSSLVKVQDQLEDSCESFQPVGVGNGKLIKDVLKLCRHSSNKDSEELVKLLNNPYLEAMIEAHDIVASKKYDSPESPPPPPLIPVTPIPQYNGPTTEAIRMVGIRKTDEEPLGITVRNEEDYLVIARILAGGIIDRQGLLNVGDIIIEVNGSEVHTPADLQQQLQKSMGSVTFKIRPSNTDIIVPTQTYVKALYEYDPSKDSLLPCKDIGLSFKQGDVLQILNQDDPNWWQARRLDSMSHAGLIPSQELEERRRAFVRPEYDHATKSTMCGTKIIRKKRKTMYQSRANAEFDKAELLLYEEVARMPPFERKTLILLGAQSVGRRTMKNRLIKDDQGKFGAPIPHTSRPIRETEQDGKNYFFVTREAMEADIAENKYLEYGEHNGHLYGTKLESVRAIIRSGKMCILDCNPQTSEFMPYVVFIAAPPIDQLKNMHEFGRHHNYSSKNLTFDRAMGRHGSRRARTMESLASLYEEEDLRNTVEESARLQRAFDKYFDLVLLNTNFDKTYEQLKEAIDALSTEPQWVPISWVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M938</accession>
    <name>A0AAV4M938_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_545021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002007">
        <property type="protein sequence ID" value="GIX68874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M938"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10179" checksum="004535BE0F9BED33" modified="2024-11-27" version="1" fragment="single">MQLRFSHDEPSYTCSSCRTIRTKYCFSSSVSSHENPLKHRVNVLHSFFNRIRKEEKYTTPPSSPEFTPPSSPCDSPVFDIKHPVYIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDK2</accession>
    <name>A0AAV4MDK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_156861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002081">
        <property type="protein sequence ID" value="GIX69762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9626" checksum="5C3B6508F6BCD7CA" modified="2024-11-27" version="1">MWKRHNPVGEKGKASFAVELSEVQWLLIRRLSQTVKMSCKEGFLKAKHISASVSRSVFEVAGKLDVECEKWIALLFVIFYVKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6H8</accession>
    <name>A0AAV4N6H8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_183043_1</name>
        <name evidence="2" type="ORF">CEXT_38811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0696 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020565">
        <property type="protein sequence ID" value="GIX80033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6H8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015034">
        <property type="entry name" value="Bles03"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977:SF1">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08939">
        <property type="entry name" value="Bles03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17666" checksum="0DAD3DEE69F1B2B4" modified="2024-11-27" version="1">MDNILLPSNCKNKEYIYMPSDQDDFEEVTYRQGGKWMLYTEDSNHDSHWKSLMPLYNEGLILGLKASATKTTELQIKINSPYKIIMCYTEDSDDLEYVSKVVRAIRSATKYGQIMYYKSNAASMDGLYPHEGKKVCFQVYAYCQRRIVHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAV8</accession>
    <name>A0AAV4NAV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_808261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020611">
        <property type="protein sequence ID" value="GIX80609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9607" checksum="26B0FCDF7E078EBC" modified="2024-11-27" version="1">MDRGQQQKTRITFSHFNKRFKKTVRRHSDRISAISRNALQERWGRDFFPLITAPASRRTCAKEGTYRPPQEKQKPQNSAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NF95</accession>
    <name>A0AAV4NF95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003336">
        <property type="protein sequence ID" value="GIX83484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NF95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9019" checksum="E71ED500FE35CA72" modified="2024-11-27" version="1">MIEAPEPKLPPIMVRYTDNLKDQIAEISNQFEDDVRIKLAGEQLKIFPQTLIYTEPSLNILLMGKSNSTSSPLRINARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFP1</accession>
    <name>A0AAV4NFP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Techylectin-5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_8491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003214">
        <property type="protein sequence ID" value="GIX82182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143:SF458">
        <property type="entry name" value="FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="1">
        <location>
            <begin position="53"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="31777" checksum="C28E217E8214EF7B" modified="2024-11-27" version="1">MKSGIVSHSFSACSEPFLLLIISDLGLTASIEIPHAEAVDSKSDEFKADECKCEKHFKPMDCSEIFENGNTESGIYTIWPRNRLANCSSLEVYCDMDTAGGGWTLIQRRGDFGNGEDYFAKNWEQYKAGFGDLKKEFWIGNDNIFIITNQAQYSIRFDMTHGNGKTAFTHYENFWIDDEDKMYLLHISEASGPGGGAISNHDQCPFYTRDRPNRLDGKVMEKVHSGGWWNNAWPSSNLNGLNLNGQKITDVDGIQWMNFGGFYNSLAATEMKVRPKRFHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NII8</accession>
    <name>A0AAV4NII8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_272620_1</name>
        <name evidence="2" type="ORF">CEXT_496771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020968">
        <property type="protein sequence ID" value="GIX84463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NII8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="371" mass="40417" checksum="E203EB54B663C183" modified="2024-11-27" version="1">MNTLNETLDALEYDIYKHDLMHQISESEHTNPSRPNSRDGELDDFDTSSCSSLSAVTVLSKDMKKNFDVNSTGSRSLEKNLSEEFSTFRNSIYGVGKVMPGIFAETTGKDIERSPDGSEEGSQRKYETETIDIHAPTSRVPSPPNKRSKTLTNSPVVFSEDSLSESAAEYAEESSNASVSYSNGSALYSDISPESPTSYSIESSNAQTVHSMNSTKESNVYPEESTKAPTTDSVESITVCTALGPSNASATSPSEDEGKSSASERQPNKCHGHKSSNTERKDQAVKKSDKRHLLTKSPSTESVTTISTDMTTDSLESCPSSPTLERSSLLFESNTKFGGHVDKQVDPKFHSIFQIATKIQEKLVLPENRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJN2</accession>
    <name>A0AAV4NJN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Wee1-like protein kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WEE2</name>
        <name evidence="7" type="ORF">CEXT_655891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021009">
        <property type="protein sequence ID" value="GIX84883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF185">
        <property type="entry name" value="WEE1-LIKE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX84883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="27600" checksum="AAFE9E75E9900C24" modified="2024-11-27" version="1">MPKKRLVCNETIPLIWKNVTEHIVKYYDAWGSLAMKIRKKMHFSEGQVEKMHFPEEEVKTIILHISRGLAYIHEQKYAHLDIKPSNILISNKLRYVSPSFDTSNEEIVVSGIEMETIYKIGDLGHLTSFKSKNVEEGDIRYLDPEIFQGKYVDLAKADIFSLGITIYQACTLKDIPKNGVGWIDLQNGKLEYVPNYSEELNTLIKKMANPSNSERPTAADLEELLNQDDVQIMEVEEVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPI7</accession>
    <name>A0AAV4NPI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleic-acid-binding protein from transposon X-element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ORF1_97</name>
        <name evidence="2" type="ORF">CEXT_725151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003573">
        <property type="protein sequence ID" value="GIX86220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="614" mass="71056" checksum="30DE616348C3B50E" modified="2024-11-27" version="1">MFVLYSGTNRFSPEFVQPRGRSYYHQAHSGTSYDDDCRHRYAQTRLPPGIKLEMRQLNLERGDSGYLKCTSCTYDRYLRPAGLPSREPWQTQLEAEDEALEKERHRTRYFRDDCHQRHRNLNVNVQWKPPKFGKGDSDHEKLSDLYLRPAGLPSRERKPDMNLERPPKEEEKVQHSTKERREYNSHNDEDKKSTDHESTDRAIDTSQFDYENLITWIRTLSENSVLQNIFSFFDTLSVHFFNERTPDSIKQAYRLKDLALAAQNTMVVHLSGELQALTDHYKKEMNAMSQMLQDLKSRLPPPESVAPINKKTKRTKPLTSSNTKKTKSSNNDIVLSNKFSALDNGTDIDTPETTLNDHANEIEITKAINDMQVDDEFTSLNDSMKINDSKKRPYIPPIVVDKVNDGKKLMGELNALTNEKVKARVVGDKLKIFPPSAEAHRLIRSEITDNRKLQAHTFLLPQDKQLKIVIRGLSHDYPTEDLIEALRNESFHVEYVTQLKHRVVKVTCPSFWLFCQKLTNQKNLFNLEFLNFFKIKCEPLRKKPGPAQCFNCQNSFTIPGFALETQSVGNVQAHINLETVQNQRTLLPAAPCDQPSTPNICEQYPTLYKCYRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQA1</accession>
    <name>A0AAV4NQA1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable ATP-dependent RNA helicase spindle-E</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">TDRD9</name>
        <name evidence="19" type="ORF">CEXT_78701</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01003637">
        <property type="protein sequence ID" value="GIX86992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001760">
        <property type="entry name" value="ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF113">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE TDRD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="8" id="KW-0221">Differentiation</keyword>
    <keyword evidence="10 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="12" id="KW-0744">Spermatogenesis</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="143"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="372"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="16">
        <location>
            <begin position="933"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="GIX86992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1393" mass="158739" checksum="4A94CFB549F8A39E" modified="2024-11-27" version="1">MTTSNQITLDHISSYLTLNDEIQPLDIAPTATGGAGIDNLDQYPPPQIVIPNWRRAGTEYVEKIRKRDKELEDARKQMQGLSINSIGSLDTLDDVEDTTLPGDGNSRNDLENDLTQTIYDTYFKNSPKYDPTLAITHYRNEIISQLQINPVVIIQGHTGCGKTTQVPQYILDLHKTKGTHCNIVVTQPRKIAAISVARRVCYERKWELGSIVGYQVAMDSHTSIDTRITYMTTGVLLEKLVHAKRMDMYTHIIIDEVHERNQDTDFALLIIKKFLMTNCPRVKVILMSATFDTSEFAEYFRIFSHSQQPPTVNITGKTYHVTEHYLHELKTLLKKVPEFDFKNPCIDPCLFEAVLKLMCIFDRIEKHEQKVPNDQNYAYNRGAVLIFLPGYEEIRALSNTLATASFNKNFWIIPLHSTITIEEQSKVFRDAPSDQRKVIISTNIAESSVTVPDVRYVTDPATGYTSLQLEWASKANCIQRKGRTGRVDIGKVYRMVPMQFYNALSDYGIPEIKRCPLAKTILHVKKLSICKPEEMLAYALDPPDLGDIATAVLHLKEALALTSNDDPCDGNLTFLGRIITNLPLDIKLSKLIIFGYAFHCLEECIIIAASLSLQSFFARPFLKNFARCLQIIGKKLSRLSWADSTFSDCICFLNAYQTWKTLSIQGQFKRPGGLSENEWAALHFIQMKRIKEVDLLVKDIKKRLEYFHIVLSNKPRYENNEESNILIIKMVIAGAFFPYYYVQESLDESKINRDINENNPLSTVLVSGLPSRHGILYASALKEMFSGCSENIAIEFEESRAYIKFMNNYDKNASLIHPAVYMAIKMRKLQMPLNLVVFAPDEAERKTQQLLSKNGLTSDTLASNRITVSGTALKKMTLPAMDVLFTDIFITQVNNCGHFWARYVTPEISNLVMFIDTTINRAKGADLKHLTQPPKINMLYLAPYIVGSTDKLYYRAQVQEIKKNKATVFYIDYGSIAKINFSDLRDIPDSTPDVLNTPALAFECFLSEVRPSSHKNINGQWSNEANKWFKNEISGRHLHVKIYSVVQGALRVELLKYANDGRVLNINKELIKLEYAEPAEENIASKQNHEMRINSYNTPNSYSERASKDFELSWLDTPDYTTIQRTGRSIRLHGPYNPLEVSFSGLSHIDCCKSVRIERDSVNSVSFDGDPQNSFSSILVAANIGIGQFNSELILRSTTLMPKIRGLPSLICLLFAPFVEFRTNKERTSYTGALCGLGCDPETGESVYPDHDIELSFDTEITLDDIQEINAVRMSFNLLYHSDTDKLQYSFNPISIVQEETRKYVFNLLRRKECQKNLSVLSLHKPISLLAETDDIDQNLYDLYKATESVTSEYHEYECKLCFVTVDSSRKLLFHLNSEKHQVKENQLRLQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR76</accession>
    <name>A0AAV4NR76_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transposase IS30-like HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_93191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021212">
        <property type="protein sequence ID" value="GIX87178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase IS30-like HTH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX87178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11993" checksum="93CDD1AAEAB989DD" modified="2024-11-27" version="1">MDLKGKKITPEERKIIIKLRNEGKTLREIGKIVGRTHSSIQRVINNYTSSKSIISKPCSGRPSKLTAREKRYVFKSVHLNPRISAFQIANDVRERFKKHSMKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVM8</accession>
    <name>A0AAV4NVM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_355311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003701">
        <property type="protein sequence ID" value="GIX87641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9172" checksum="4BEC79FF039F1332" modified="2024-11-27" version="1">MSLQKDVHFKPSFFFLSFLPFQVGSHSKGRPTRSNAGMNQEVLDEWGVEEDCPRNGTTNGWFNIVAWIHGFVLCAAVSIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVU5</accession>
    <name>A0AAV4NVU5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_525042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021382">
        <property type="protein sequence ID" value="GIX89012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048208">
        <property type="term" value="P:COPII vesicle coating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06401">
        <property type="entry name" value="PB1_TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034857">
        <property type="entry name" value="PB1_TFG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033512">
        <property type="entry name" value="TFG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15335">
        <property type="entry name" value="PROTEIN TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15335:SF7">
        <property type="entry name" value="PROTEIN TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX89012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="283" mass="30813" checksum="EF28CB90BE48EFDC" modified="2024-11-27" version="1">MAVNSYGGGGTEEGGYAQLDLSGKLIIKAQLGDDIRRIPIHNEDITYDELVLMMQRVFRGKLDANDEVLIKYRDEDGDLISIFDSSDLSFAIQCSRILKLTIFVNGHPEPLQSDEVKHIRTELQKIRNQVNQLIDQLEPRQSLPGNRGEPDKGIINAQASNTPNAAAPKEFDPLSSKESGEARNKVATSFGLQEDGRGGSPDSISSLGSSASQKQPQQIQQGVPPPTSMYQSQQHQVYVSSQNNPGVPSHHYFPGTGAPVPHQQQQQTTAAATTTTISCFKCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NX48</accession>
    <name>A0AAV4NX48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_383121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021368">
        <property type="protein sequence ID" value="GIX88875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NX48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14348" checksum="2CA828397689E6A7" modified="2024-11-27" version="1">MKLRNEEKKRKMIVTGRREKKTSEATWSWTMAKREWVQVLCCFGNDNQSGSKPTKQLIHLKERPDFIKTVEDITKISQTNKHSCIDFLGFSNINGSLFNGGFDHICLEAKSIDNRSKNKLDQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2Y9</accession>
    <name>A0AAV4P2Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Disintegrin and metalloproteinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_594711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021580">
        <property type="protein sequence ID" value="GIX91404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11918" checksum="B81BB7D254346434" modified="2024-11-27" version="1">MKYPKCVSTFLPFFPAAGLKLHATPAEAERLKRLYPENEKFIANIPSRYYEVIYPVQVRQHQKMGVLTRETDANKTGKHYYSTSLLVKAFNYKFKLDLELNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P523</accession>
    <name>A0AAV4P523_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_558521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021535">
        <property type="protein sequence ID" value="GIX90851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P523"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12573" checksum="E5DAC0CE29C249CB" modified="2024-11-27" version="1">MTDVAIFTFRKLSSRHINIFYATIINTCHVNVYSTVSVRPISSFTRPYNGHWAHFTAQAVTVRKTKVSAHFYCSKQDSARVAIAAHPLLLKNNTTPGANTKNYGDTTLTIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P553</accession>
    <name>A0AAV4P553_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroline-5-carboxylate reductase catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_312571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021563">
        <property type="protein sequence ID" value="GIX91158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P553"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX91158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11638" checksum="C5A70A24F0597C11" modified="2024-11-27" version="1">MRIGFIGAGGMAQALARGLISAGIQFESRLPRMQMSKLDEREICYIVVTYLSWSTVEEDKITQKAYSRTPGYKAGNQTLSRKRKEESLPGSLQGRTHISSRSLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8M5</accession>
    <name>A0AAV4P8M5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_770291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004117">
        <property type="protein sequence ID" value="GIX92358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8M5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10418" checksum="D362E54F9AC10404" modified="2024-11-27" version="1">MKPKFSQIQQFLSHLLPGNRLTLFDRRIMPHRKSLSNKRNTLPLNLLSDTFIGYPLFEEDGPQLSVRPSGKEEPLGREAIKQSGSLSRRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDC2</accession>
    <name>A0AAV4PDC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_115215_1</name>
        <name evidence="2" type="ORF">CEXT_187121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004342">
        <property type="protein sequence ID" value="GIX94146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="23861" checksum="1F21B8175B0198D8" modified="2024-11-27" version="1">MSSPPHTSEYSYLGPLSTSTLYGHSEDWQWSPEDKYNHYTYLTSSSTSQEPLDYSIGSSMFFSNEENVDSSSYKEKPVNSDSNYPMDNNERHEERPADEQVFETLGQTVIKHDPYQYEDYDEIPPPPKKRGRKKKEPNGMSYEYINTPDGVKCVKQERIAESSFLSHGLDIVIIGINPGLMAAYKDIIMLDPEIISGNVSFCLVLYQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKF8</accession>
    <name>A0AAV4PKF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_318091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004635">
        <property type="protein sequence ID" value="GIX96359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9312" checksum="0CFCDE9883E6D228" modified="2024-11-27" version="1">MIRKLHISTPTLVSHRCYVIKTGRQPSQSEKEDSVKFKEKIAGLCRQNKINLQTRSIFRKGSFLQSFCQSKVYQSVHWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSZ8</accession>
    <name>A0AAV4PSZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Receptor-type guanylate cyclase Gyc76C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Gyc76C_3</name>
        <name evidence="7" type="ORF">CEXT_325111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005215">
        <property type="protein sequence ID" value="GIY00713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Receptor ligand binding region" evidence="6">
        <location>
            <begin position="67"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY00713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17468" checksum="493A58A8F344BF64" modified="2024-11-27" version="1">MPNRKYWIQWSHWSTAQLLKLIMVLFGLFAIMNNNKSNVSAETFTIGYMTNMQGRTNTQKQGIVISGAMSYALDVINSNASYLNGHKLRMIYNDTEGDTLIGTYVTIEQWREGAVAFFGPEDSCAVEATVAASLNLPMISYVSTFQNLLLFYYCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PT95</accession>
    <name>A0AAV4PT95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_145261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005168">
        <property type="protein sequence ID" value="GIY00345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PT95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8817" checksum="F3B668F51B574B8C" modified="2024-11-27" version="1">MVRTFRFSRYGRWSSLHGKSYFDESASLERVSVLGSSLNTSYLLGDLNPTLVRRRRAPDPITLGDATVVLIHTYGKGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXY0</accession>
    <name>A0AAV4PXY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Toll-like receptor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tlr8</name>
        <name evidence="9" type="ORF">CEXT_472321</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005222">
        <property type="protein sequence ID" value="GIY00752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365:SF530">
        <property type="entry name" value="MSTPROX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365">
        <property type="entry name" value="TOLL-LIKE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043360483" evidence="7">
        <location>
            <begin position="17"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="TIR" evidence="8">
        <location>
            <begin position="139"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY00752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="23804" checksum="F3B78031FB121AB5" modified="2024-11-27" version="1">MLKIFCSCIYLTCILAINIRELVAQNFTTEDYRSKELEGCRLENNSEIVGLVAFCTQYQSIKRLIYFQGLSLDFSYISYCIPKVLDVAKIVYCTLGPLLVFGTVLVLVWYRFKWDIKYFLFLARSRTRTFKEQVICDRYAFDAFISYCDKDLPWVRNHLLPAIENDEDRISCCIPDRNFIAGNCALNTTASYFTEQNNCFSCEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0W6</accession>
    <name>A0AAV4Q0W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_397491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005560">
        <property type="protein sequence ID" value="GIY03298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="17646" checksum="EFAF961674C6A3A8" modified="2024-11-27" version="1">MCCSICKDFIGAVLSSGESSICDPFYVLSVKVLIAPKLKTIIMQKSLKKLSCFYHNDILFPAVSLHKSKFNSVVFGLVLGLCIWAGRSVKAQCVPEIESPNLKRKVGKEGLKNARCHSHVITSALSVIKNRLSWGTKDKPQCIKGLSRDRIQPLLPLMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q613</accession>
    <name>A0AAV4Q613_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_126778_1</name>
        <name evidence="1" type="ORF">CEXT_806761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005630">
        <property type="protein sequence ID" value="GIY03831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q613"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24309" checksum="2218FEB767101D0E" modified="2024-11-27" version="1">MNELLFASIFTKSNKLNSIERRGQATGPTGLSNLPPGKTFTCDLWKSGTIQKRIRLHVQHGPCEAGAVPSNGESSVRSLLAGSGVPMADSLIKFHPICFSHFKIPFFVGDAVQLGVYTGGPLHDFKISDGVLLKMSECKSQKSDSFKKYRSRCMKINRHYGSGSPVCQFDKGAVVMQEIEGRFYLLGLSSYAISCAAPRVFYDVNWAFEWISVLSTLLATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8W5</accession>
    <name>A0AAV4Q8W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_598221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005718">
        <property type="protein sequence ID" value="GIY04511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14077" checksum="A999439ED9B3C238" modified="2024-11-27" version="1">MTLLNISFNGPSISLELQTPRTLLLLLNQALERRDQDGKAKRRILLDVYANDNRDGLDFPLHGWPHDSSSRDNRCPKRGLRRQEGKAKRGILLDVYAKDNRDGLEDRFASMVLCCLHDFPVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFU2</accession>
    <name>A0AAV4QFU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_80671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006188">
        <property type="protein sequence ID" value="GIY07990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="22181" checksum="434E7A924EB1EA3A" modified="2024-11-27" version="1">MPACLFVVNEQLISKLRAVDLKFAKQVQIAISVFAIAEYDIRKSRNFSVCFKEGSRRCCKSPNMTPLEFVPNCGVSYKSDVKIWYSVVDSYKSDAKIWYSVVDSYKSDAKVWYSVVDSYKSDAKVCVVDSYKIDAKVWYSAVDYYKSDAKIWYSIVDFYSDAKIWYSVVDSYKSGAKLWIRCCRLLQEWEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QR57</accession>
    <name>A0AAV4QR57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Inhibitor of Bruton tyrosine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Ibtk</name>
        <name evidence="14" type="ORF">CEXT_697701</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006551">
        <property type="protein sequence ID" value="GIY10667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QR57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF2">
        <property type="entry name" value="INHIBITOR OF BRUTON TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="10" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="RCC1" evidence="11">
        <location>
            <begin position="144"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="11">
        <location>
            <begin position="198"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="13">
        <location>
            <begin position="566"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="13">
        <location>
            <begin position="711"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="873"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1053"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="873"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1055"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY10667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1148" mass="129634" checksum="AB65D28879E06BC8" modified="2024-11-27" version="1">MEQCIERDCTSKCKSSTHAKQILTCVPFATTSQLRTYAVWLCHNFAAVSDNFGRHLLHLAAACGKWETVEWLLKQCNAEIDIKDRESGWSALHRSFFYGQLACARILCMNGASLKLIDHEGFTPLDIIVKDRLPYIEYQHSDPSDVYAWGSNFNYNLGVGNSQCKVIPDVLEVFRKDFIDIKQVEICKFHSVFLSTNGLVYTCGYGHGGRLGQETEDISLVPSLVKGLGNQLVMQVAAGQDHLVLLLENRQVWSCGLNVYHQLGHIPPPERLLAPKALSLKFLKGKAVIGICAARFHSVIYTKDSVFTFGLNAGQLGHPKGDRTQIHPRQVSALYTEECHLTHVATSDGAIVCATSRGDVYVLHEYQIRKIASRQLEILKLSVVGGHLDSRCDVAGVREGGGLELRVALLTKSGKVFLWRQTDPYLRRCLFTSLKELIISDIHINHYSIGMITSDNEGYIGTISNFKGKRSAPPTNICNPTLFNIKTSKGLTVLLDTDDCHFIKAKKLPNIYRGTSITSDSKGRNFAVLQSNAKMGLVEIPMISNSKIQQDFTRLYLETHELDDFHDIIINVDKRKFAAHKFILASRSEFFKKQFCKENFSDGELVIDNMKHEAFEQILKFMYTNHCDFLVNGYEVKWGNFKENGKKNKSNAKNKASNPVHIVQEACKKLGLTRLSKRLEGVKLVNGKISVNEPRTMPRLTFSRLSLSNLCDVNLISSVNEASSSDKKTVFSCHKCILAARLDYFHSMLSHCWEESSRLNNLKLPIPSRILEVLINYLYSDDAGEISDSDDVEFLCHILMTSDQLLIPHLKEICEFSLVKLLVSDEVMEELSAYYRNLVPCMYNRRISMNRNGVENDLELLEKEFPVSDASVFDKSRSDSHDGKSKTRRRCASWRSDSKDMSSVIENDVKSLDNNIVLDILIPDIIENTVMSTSPIVKQSTVTKIINKQEAPKPGQWVMRCPTEEQVLSLDQIMLKEKRGLTPLQKKTNFPDKKPLPHLSQKQKKMMKANKVPFSSEISIPNSPTSTNWCPWGKLPEQSPPSPSFWDILAKKELQPSSSSKENSTPVKSFSTAEQKKSNLRDNSPVVENSQDIVISLHDIQLAEEQKLRRAAQPTIKPLHILNIEDQAIEEPWHCTMLTIIIKKNYCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3N6</accession>
    <name>A0AAV4R3N6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_324671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007183">
        <property type="protein sequence ID" value="GIY15032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9324" checksum="EBEED5E27802103E" modified="2024-11-27" version="1">MSGIMASQFELITLHEPTLPISESDQGNRVGGVIIKWYYTSRLSSSSFQGHTQTDRRHLNVIKCLVEVRTLLLRAFNDLNTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4E1</accession>
    <name>A0AAV4R4E1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exportin-T</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Exportin(tRNA)</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA exportin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">XPOT</name>
        <name evidence="3" type="ORF">CEXT_309341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Shuttles between the nucleus and the cytoplasm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007394">
        <property type="protein sequence ID" value="GIY16605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071528">
        <property type="term" value="P:tRNA re-export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045546">
        <property type="entry name" value="Exportin-T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040017">
        <property type="entry name" value="XPOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952:SF11">
        <property type="entry name" value="EXPORTIN-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952">
        <property type="entry name" value="EXPORTIN-T/LOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19282">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Exportin-T C-terminal" evidence="2">
        <location>
            <begin position="70"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY16605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="701" mass="79474" checksum="65CF913961AF9898" modified="2024-11-27" version="1">MDPIAKVKIVESYATILKQAGVLNFTGSPDDEDFMVKLSTLVNTMGTALLSSWTRLQKSKDTRGMTIVANAIHDKIELLLKFLSNDDDEVSQAVVEFAREYLQFLKNKASVKAYGTADSSNVERILYIVINKYKYDLSTDFSYQDEDEAYFQEYRKLLKVLFDNLAMLDLDLVFSQTKNMIASTLNRWQTLPYNELEVAITFLYLLGEVVPNCHGTSDGNISDKKTEINEMLHLLITSGVSRQGHKAVILQFFETVVRYEKYFGQEPVLIPEILAAFLDDRGLRNSDPHVRSRASYLLSRFIKYLKTHMSNYTEGILKQLQDLLDLALPVNGISHTLVSPDDQLYLYETAAVLIVSGSFSPETKQAFLKSLLLPVAEKFQLLLQKLPTTSDELQRREIAKCMNHAIAVTSRTSKAFSNQQTMQTNGCVEVYLQALQIFLGALNLPYEQTTLQSAVRQYLHRMVVCLESEVLPYFPIAAEQLLKSSDIQKKVVPFVQEIFMPFVTAIFNTLSVPIDENDQPAQNERQQLQRSYFLFIAAIVTSNIAEVISTQSVQNFRQVLLTVIQGAVHFPDPVAQKTCFSILRKMVELWGGADGLDGFVEFMYHNIVPACFMAPLKETFDLNDAQTILALSESALCLRTVLDKRGVEFVTFLKTSYLPTLRINPEKMDEYCRALSSDSKAFKNYLKFFLPKCKDVAVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5C1</accession>
    <name>A0AAV4R5C1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KASH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_78071_1</name>
        <name evidence="2" type="ORF">CEXT_787321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007286">
        <property type="protein sequence ID" value="GIY15816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5C1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="372" mass="41246" checksum="52C1F75294AA6CE8" modified="2024-11-27" version="1">MRNQVSNNFRQSHYRTVVFSPFFVTGCGETMIEYFTSHLANIPLSSTFKKGFRNAKRKLFHFNKALKNLTSALNHREASDFELDEGPLNKHRRLTLDRWTAVNSTANMDKMRMERNKTTNVIKTGLLTKDIGVLCSDLIPVNDKCIMVGTTGIAALKAEYGDDFTNFEIIQDVGYSSESSTHLSSDDGISVGGDRYFNIRVYNYADEKTPPKTINLKEDLDKADSSKQSSSLASSVGSSSGAPSFNDSGLGAADLLVTRETTSPEIDKTLLTDDCDPYDLCLPGEESDFLETVLDNCVDFCTSESEKDGNGIDDLQYNLSGIESDDSADNFHNKSVNSDGRETRARPGFEPGTSRTQIENHTPRPPSRKSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R978</accession>
    <name>A0AAV4R978_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_202321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007397">
        <property type="protein sequence ID" value="GIY16653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R978"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9202" checksum="346ED4494ABB41B2" modified="2024-11-27" version="1">MMLITIRAISHDYVHYFHLVLNVCRAKCLEPQCVNSSRNHKDSGRPFYFTSPAMPPMADVLGILGNGWQRGQLKCPSPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGM0</accession>
    <name>A0AAV4RGM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_622511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007789">
        <property type="protein sequence ID" value="GIY19749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="22395" checksum="8568884468E90454" modified="2024-11-27" version="1">MRFSSDVKQKFLGMGPENRDNKNSRETRTAFKGADRKTRCVEWSHIARNYQGSYCVQKNNSDNIIPPSDITVLIKNTKIKSVPDFDSICSKILKKFSNVTIIKLCYLINKVLEDCNYHPYTKTWKRSYEPRKLFIIFISLLSILSKITESIILNRLNQFVEPNIICKEQFDLEGTSPPPSTSKSCGMHHFWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJB7</accession>
    <name>A0AAV4RJB7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BTBD10</name>
        <name evidence="5" type="ORF">CEXT_332351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007839">
        <property type="protein sequence ID" value="GIY20103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042327">
        <property type="term" value="P:positive regulation of phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18318">
        <property type="entry name" value="BTB_POZ_KCTD20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000017">
        <property type="entry name" value="BTB/POZ domain-containing protein 10 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039886">
        <property type="entry name" value="BTBD10/KCTD20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039885">
        <property type="entry name" value="BTBD10/KCTD20_BTB/POZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21637:SF0">
        <property type="entry name" value="AT10158P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21637">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16017">
        <property type="entry name" value="BTB_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="168"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY20103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="290" mass="31995" checksum="88240F9B1FAEEEAD" modified="2024-11-27" version="1">MRDTTTTTKLRNVCSGKKRVGENKSQKPSHSSEWDDFIGLKQGEKMPSAFTPKIGERPRVERYSNSTKLKPCLVSRMGDQIESSSSPSSSGSSRDSPPLTMGPTQKASVAAGSKNKHRTHQLPQQLALALNLSSEHSCMGLTEGNHQKSCSTIPTVNQAVVAPPVSDERITLVVENTRIVVDPALFAAHPDTMLGRMFGSSLENNFTRPNERGEYDVAEGISAVVFRAIMEYYKTGIVHCPPSVSVPELREACDYLLIPFDANTIRCHNLRGFLHELSNEGARQQFEKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKI1</accession>
    <name>A0AAV4RKI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_686521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008061">
        <property type="protein sequence ID" value="GIY21862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7773" checksum="3A3942A68246BD59" modified="2024-11-27" version="1">MTPYGGKEKLIFNSRPFFHAPFASVVTRFAPGSTGASKGKREEKPPRRAATCTEKPSSSDHPRFFSRLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQ55</accession>
    <name>A0AAV4RQ55_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_261671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008323">
        <property type="protein sequence ID" value="GIY23850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQ55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11454" checksum="EAE5F6B4033E8F47" modified="2024-11-27" version="1">MVWIPVLALEVSGRVFTPLLILRSESKPSIPLSLVLPAERQQVSRKTPTASSFCHPAKLKYLLSSLRGTMLSWPRQDPVKMVPSSRTRINELRRGQQGPGCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQW2</accession>
    <name>A0AAV4RQW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Neurexin-3b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nrxn3b</name>
        <name evidence="11" type="ORF">CEXT_241</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008317">
        <property type="protein sequence ID" value="GIY23812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000029">
        <property type="entry name" value="neurexin-1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050372">
        <property type="entry name" value="Neurexin-related_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036:SF49">
        <property type="entry name" value="AXOTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036">
        <property type="entry name" value="PIKACHURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 8" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Laminin G" evidence="9">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="139"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="9">
        <location>
            <begin position="179"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY23812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="30527" checksum="89116C3EF0CEB80F" modified="2024-11-27" version="1">MLPLGMLALNYSGIMSSYDELSSQSVVKATTRRVDDGQWHSVSLKRSGKSGRVTVDESAVDFITPGNSNQLDLEGPLYVGGVGTSAQGVLIPSELWSGSLRYGYVGCMKDLIINGRTVDIAGVSQKQDSGSIRPACHTPTPQCDSQPCLNNGLCLEGWNHFTCDCSHTSYSGAVCAKDATTLSFDGTQYMKITVLEGPTQAEDIRLRLKTTRPSGLLFATSSEKSSTAMSAALEAGRFKLVLNLGDGNKVFFVGQGLNDDQWHTLHVTRRGQSMDVKSRLGGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTX9</accession>
    <name>A0AAV4RTX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_243942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008262">
        <property type="protein sequence ID" value="GIY23328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="20294" checksum="91C324A9A10E84E7" modified="2024-11-27" version="1">MGAPTGEGEGCEVMGLPSIESSEASVTYKHHCFDGKHCSNCCSSDLAFSYALLDYLIVRLFSCRFLFCFFNYDVPVLDLKKRGKFVMLVFGDLQPTSEKNRYFFLLPPFYRQNIDDDEKGLKECSVVALKMQKRTVTASESDKKKKSSSRTMPQGQRFFQTWERTSQSLITVTSKLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVB8</accession>
    <name>A0AAV4RVB8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein DEK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_119114_1</name>
        <name evidence="2" type="ORF">CEXT_437181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008318">
        <property type="protein sequence ID" value="GIY23823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000779">
        <property type="term" value="P:regulation of double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044198">
        <property type="entry name" value="DEK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468">
        <property type="entry name" value="DEK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468:SF1">
        <property type="entry name" value="PROTEIN DEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="41497" checksum="BA90522C36DAF8A4" modified="2024-11-27" version="1">MQRIKKKRTFQPKDNNDDEEESKDEPRTRRLRSNTVEKGKEEPKKKAEVLGKRKPEISKSTPVSNKKQKISKDEDLKKGKKNTKVTGKRLRSAVQSSPKVQKSVKVTRTSLKQTEAKPETKRLSLRKATLLKTANAAAAAASASATASTSAVASTYISTGKSKVYILNCGENKNLSVIPEIKENVDKSDMKFLRYLYRILYDQWPPKEIDELKREILNFSGYNFKKKSQDLEKREQVLKKMPDSSVIEICKILDLKQGTKENMISDIIKFLLKPAKIVISTVDPLDPSMQPVVRLQRISISTNNTSKAITKSEVKPPVKISKRVRIPSVKLDIYDTDIKSKLFLPEKVPTKHKNRKKGNHNQELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RW22</accession>
    <name>A0AAV4RW22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008421">
        <property type="protein sequence ID" value="GIY24566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RW22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10165" checksum="544E7395D8DDB73D" modified="2024-11-27" version="1">MGSDDLNKKPSGFQSLFTQPHCHPLPSLRTVLLCGGNKENNTTKEEKENASLAKSLLFFLGKGKNLLCDVRLTCLLKYKVAFYRKVIRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S589</accession>
    <name>A0AAV4S589_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_329541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009057">
        <property type="protein sequence ID" value="GIY29353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S589"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9764" checksum="C79BBC92D4EEA290" modified="2024-11-27" version="1">MSLNLLLGLARTFYRRKLNRSTCLDDYWQERRTSEDPEDEELGMDTSDSPLVHQSFEEKVAEDSETTYKYLPFSNNLIQILAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SD63</accession>
    <name>A0AAV4SD63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009134">
        <property type="protein sequence ID" value="GIY29823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SD63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12927" checksum="0660C25D5F1B1112" modified="2024-11-27" version="1">MFAVRLLLREEVNTKFPKKLSNVTLLVYHINIVFDAWITNRTFSKTMTVWSERIFAVRLLLSEEVNRFQEKLSNVTLLVRHIIIVLKPQVGGSFNEERKSHNQKDSSIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SH60</accession>
    <name>A0AAV4SH60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_495061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009427">
        <property type="protein sequence ID" value="GIY31850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SH60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13009" checksum="7EC1E14A37B5537C" modified="2024-11-27" version="1">MDDVQSCNSMISSNNNYFKSSKSINELVLRLGQKSFEEIHIVCQHRDAKHKIPRSNPFLIQADIKKHINRHDNITNMKFSRQGKLIFSTADPVCAAQILNLDKILKRQFLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKD0</accession>
    <name>A0AAV4SKD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Gatb</name>
        <name evidence="6" type="ORF">CEXT_781431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009771">
        <property type="protein sequence ID" value="GIY34459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004012">
        <property type="entry name" value="PRK05477.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aspartyl/Glutamyl-tRNA(Gln) amidotransferase subunit B/E catalytic" evidence="5">
        <location>
            <begin position="66"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY34459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="432" mass="48611" checksum="9AC2B7EBA7C954FB" modified="2024-11-27" version="1">MIRQYVKKHQNFVCGGVRKDSNGVQLPSMKHRQVILSSNRLIFRNLRLNFSTKISTADSISKYEGVVGLEVHAQISSKSKLFSSSPVEFGAPTNTKVSFFDAAFPGTLPVLNKSCVEAGILTALALNCTVNKISTFDRKHYFYPDLPAGFQITQQFKPLASNGYIKFVVHGKTNNSPSYECIAYLKQIQLEQDSGRSFHVKGAKSLIDLNRAGIGLMELVFEPNLKNGTEAAALVKALISVLKQIGTCTCEMEEGTLRVDANVSVNKIGEPFGVRTEVKNINSLRYIARAVDYEMERQIKIIENGGLIVNETRAYDYSSKKTIFMRDKEILQDYRFMPEPNLPPIRLYDNSDKDKLENCDNVLNIDDFQKRLPVLPEKERETLICKYKLPLNVADRIVHSSGFMKIFKVAASRINDYSSICNFLFLQLGKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLB8</accession>
    <name>A0AAV4SLB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_26861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009629">
        <property type="protein sequence ID" value="GIY33372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9962" checksum="B8C6CB22ED117A47" modified="2024-11-27" version="1">MTKLSGLKASLFLKQLLDDINPSSLLECYNLSDEENCFTAGHTQTNQFPRPPRAPRAYLTRPEQFRAGKESVILFFSPRTFPPSNSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SRY0</accession>
    <name>A0AAV4SRY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_486501</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010020">
        <property type="protein sequence ID" value="GIY36202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SRY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043122">
        <property type="term" value="P:regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001293">
        <property type="entry name" value="Znf_TRAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF157">
        <property type="entry name" value="RECEPTOR-ASSOCIATED FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50145">
        <property type="entry name" value="ZF_TRAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="TRAF-type" evidence="8">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TRAF-type" evidence="4">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="367"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="464"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="168"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="277"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY36202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="525" mass="59234" checksum="6560D37AB2EF2D68" modified="2024-11-27" version="1">MAPPSWAYQVENLDPPPDEELVCSICRSVFCDPVQSPCHHVFCRNCIMKWLERNRNCPICRKRLLRSAVQDVVPLIKNMILKLNVMCCNRQNGCTGKFSLENCETHTVECPFAMVGCRNKPCKVKVLRKDLEGHEKNVCPHHYVKCKTCCLKIRTSNPNKHNCILALKKRLREKNEVIRKKTDKIKELQEEIKNMTMAQSVMFDSETSSLGSASAGDITLSFPSSSSSSSDSSSSSDDYNSEIFLVDSGYSFVSDEMRNSDRPNQDTNIFDSLYNALNSTEEELRGIDHTLDQASQNHQETSRTIANLMEDTASGDEQPIRRPAKRRHVAARILDTSEEDNDRPSEPPSAPTPKHKIWQDILRGWRQPSAGGATTSVSSGNGNLQNPWACSSSSESNPPATDTNPSFSLQPVWRRENTDQEQTESIFSPQRNRHRMFERTMALLQQEFSDSDPEWVPTPNLETYTDSSSLLSGDEGSTETLSSSNSSDEDAPSTTNMIRGNNRNADLLRRIERITLKSKRSRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSQ7</accession>
    <name>A0AAV4SSQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_601521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010089">
        <property type="protein sequence ID" value="GIY36790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11898" checksum="00A7EFA2716B484B" modified="2024-11-27" version="1">MVKVALICRCGDDSCCLHLPRRRRPSTLSSTVPKKSSQKQYLRTWVHLPSVQSAVSRESNRFSKRRHSSKEKPHTKKSRAKKNDVSRRRFYPFIYPSAPGNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SV99</accession>
    <name>A0AAV4SV99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_411011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009925">
        <property type="protein sequence ID" value="GIY35523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SV99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12712" checksum="2A726DB0EBC536F0" modified="2024-11-27" version="1">MNIGRQVSELPYSSMFVHIEGKTQDLCVGDSKHWMTISCRVRPRDVVQIPGTTSTSTQKRVVQRFGKDEGSISMFGEYVKLKGFDDRSIDYVQKAIGGMVFDAEMEKYAKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVZ5</accession>
    <name>A0AAV4SVZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TD and POZ domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Tdpoz3_23</name>
        <name evidence="2" type="ORF">CEXT_467641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010129">
        <property type="protein sequence ID" value="GIY37151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10080" checksum="6FEB3386B282AACB" modified="2024-11-27" version="1">MLGYLYTADVEGLQWESAIDLYKAADKYEILSLKKKCSSFLKLNLTPTTACDILLLSDLHMDGDLKTYVQNFIVKHHNEILTPTTGIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2F9</accession>
    <name>A0AAV4T2F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_807491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010380">
        <property type="protein sequence ID" value="GIY38945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7444" checksum="7C714B2F6ABCD442" modified="2024-11-27" version="1">MVSTGHFPTIECPNEIYRQPPADHPCTANPYSGHDGGSSTPSIPLFNNRLLREYILAGPFDMSLSLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBQ5</accession>
    <name>A0AAV4TBQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-catulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CTNNAL1</name>
        <name evidence="5" type="ORF">CEXT_685731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the vinculin/alpha-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011018">
        <property type="protein sequence ID" value="GIY43725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.230">
        <property type="entry name" value="Alpha-catenin/vinculin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036723">
        <property type="entry name" value="Alpha-catenin/vinculin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030045">
        <property type="entry name" value="CTNNAL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006077">
        <property type="entry name" value="Vinculin/catenin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46342">
        <property type="entry name" value="ALPHA-CATULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46342:SF1">
        <property type="entry name" value="ALPHA-CATULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01044">
        <property type="entry name" value="Vinculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47220">
        <property type="entry name" value="alpha-catenin/vinculin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="131"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY43725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="262" mass="29258" checksum="E13B2CA4CAB9FCFA" modified="2024-11-27" version="1" fragment="single">YKRRHSNKLKNFKKYMDKLTLLNRLKHASITGDHPRLEEFSERFSEQSDHLQEVCKLLHHVASAESVQVLSKNTEACLQVYGPQVLSACHTLFLHPSSKVVRENVEVFMDVWKALDQDVTALAQEVAELCRSSSSNPGKTEKAPNTNYSANPATTADFSRQQQSHPSPSNLNNHPAVPKSIVTANQLAVPGQPTTLDAEEQSNIAKLGLEMKQLTSEMDAETDKWPTADNDIVRRAKSMSTMAFSMYQFTRGEGELKTTQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCM4</accession>
    <name>A0AAV4TCM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_79891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011127">
        <property type="protein sequence ID" value="GIY44323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10724" checksum="A8B293BEA3E440D4" modified="2024-11-27" version="1">MRLKVVRKQIMFPISDTSYQVIKVTIPMWFGGGDTLFRIKSANEVQFVNGTGFNQTTSTLPTMAEPRGFKNPLSAVWKRFEFIKLYATAFKAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSB2</accession>
    <name>A0AAV4TSB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_27391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011617">
        <property type="protein sequence ID" value="GIY47750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="21" mass="2403" checksum="2D578E0BF236A6C1" modified="2024-11-27" version="1" fragment="single">MWTKQNSPGTTSLVIFRPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TW95</accession>
    <name>A0AAV4TW95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_624231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012033">
        <property type="protein sequence ID" value="GIY50833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TW95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY50833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13205" checksum="07E9901BA2D12336" modified="2024-11-27" version="1" fragment="single">ILPLCNFPHPVFLLAAFSMQLCVGLTVYMEFVDMKGVRYPELKLATMGWAIPMIVVGATLAAQVPIGFRLDSWWIQMQTNYFYAYSISVIIITVILFRFRIRCGGFAICLCNLNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZ51</accession>
    <name>A0AAV4TZ51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_461271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012022">
        <property type="protein sequence ID" value="GIY50767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZ51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9039" checksum="E7A13595E163B776" modified="2024-11-27" version="1">MVKNDFESDNSISFRFSCFEHHMQIIAHLVWVRRINLQVGMSIDFARVGVEETSNYYRCLQPLGVFAQNLDDKRSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U651</accession>
    <name>A0AAV4U651_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransf_25 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_149691_1</name>
        <name evidence="1" type="ORF">CEXT_389662</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012339">
        <property type="protein sequence ID" value="GIY53264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U651"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="299" mass="35323" checksum="EE0BD238F4C30732" modified="2024-11-27" version="1">MAIWYNSDISNETRYFLEFIAEKFQWSDVSSDIIMNVFCDNLKIEFCDLLIKLFRKVKKIITINKKSITINYIKLALGLPQIHYSQGDIENWLSESQMNYRRLKDVAPVSLYFGKFVYNDLITIHQSHWSTLKEWEGKISKFVSNQCLHQVKDYKTCFRNVFKLLKPGGEAAIFFCLKSGYVDWLYKLIGNPEWQKYFNGKSPEMPSTQFKYIPVSDYETMLQKIGFSVIECKIEERFIPFKKDDIISLALTYFQMPEASIEIFKRDAYNILMKYFPQNPLKPGTISIFLTVLLRKPEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UF23</accession>
    <name>A0AAV4UF23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_815211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012759">
        <property type="protein sequence ID" value="GIY56346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UF23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8185" checksum="797DCCD1DB28C97C" modified="2024-11-27" version="1">MGTFVTWMQLRICESHPGHLAKDDALKIEEYFMSLIGFRELMKLFVAGEVLSLIYWKFTGGNTNPAITLEAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UGC0</accession>
    <name>A0AAV4UGC0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">slc9b2</name>
        <name evidence="8" type="ORF">CEXT_760451</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012822">
        <property type="protein sequence ID" value="GIY56875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UGC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051843">
        <property type="entry name" value="CPA1_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31102">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31102:SF1">
        <property type="entry name" value="CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="7">
        <location>
            <begin position="3"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY56875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="421" mass="45411" checksum="840658F6B39800E2" modified="2024-11-27" version="1">MVFGFVLRNVPHINVAKDIPEEWAGNIRNMALILILLRAGLEVDANILKNNKSTCSKLIFIPFIAEFFSAAVASHYLLDMTWIWSFLMASMLSAVSPAVVLPVMLKLQKKGIGVTNGVPTMVIAVAGIDDVLALTAFEVLLGVTFSTGTLGWTIAQGPLEVLGGIIYGIILGMIMWYIPSPEQKSKSVFRFMILCFGGMFVLFGSQAVNCGAAGALGCICLPFVAAIRWKQSDWDEDNNPVGEALAFVWRIIEPFLFGLIGSEIRIEYLQPGTVGLGLATMFIGIAMRMLAALAAAFSAGLSLKEQIFVTFAGLPKATVQAAIGPVALSYARKLKLGAEVEEYGIMILTVAVLSILIAAPLGATAIALLAPRLLERDVNVNSSINEKTKTDIAETMVPMFDNNSYHSYGTKDDETEMNSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UID5</accession>
    <name>A0AAV4UID5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_421861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012929">
        <property type="protein sequence ID" value="GIY57602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UID5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15371" checksum="1A25EF68B189AB13" modified="2024-11-27" version="1">MMKCGQRWQKPRLGSVRGGSVALKASFLITLITVTESLPRRRKGSRRFATNAHGGERNVWSLRSAVIRLQRRWVSFVIVERHTANSQREIGFCCFCTEHAGANLDCAVGTDNGFLGSILPHFYTRSFNIGNKMVRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULD4</accession>
    <name>A0AAV4ULD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LDLR chaperone boca</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">boca</name>
        <name evidence="7" type="ORF">CEXT_332191</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MESD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013087">
        <property type="protein sequence ID" value="GIY58676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019330">
        <property type="entry name" value="MESD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17600:SF2">
        <property type="entry name" value="LRP CHAPERONE MESD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17600">
        <property type="entry name" value="MESODERM DEVELOPMENT CANDIDATE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10185">
        <property type="entry name" value="Mesd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0879">Wnt signaling pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY58676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14911" checksum="C95A50C7DEA10F9B" modified="2024-11-27" version="1">MFGDQVQSEGNPTERETEEITGLWQSSLMNNHINVERYPIGQDRVIFMFKDGSQAWEAKDFLVKQERLELVTIESKEYFGKHSSKGNPQSSAHPLKSFAEDLIMQIPQLHGNANFGISSAVSAGSTDFQEDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMX5</accession>
    <name>A0AAV4UMX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_712271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013164">
        <property type="protein sequence ID" value="GIY59118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17170" checksum="940CE7218924CE4E" modified="2024-11-27" version="1">MIRRKKLNYHSLSRNTPDVKPFFFLQLGTSITNFANVNNVVTSPASQSAATHILRRELSLVVASKQRWREHTRLSNLASLLQLCNQNVFDLSALDETGFEAAQAKPDVDCGSVGERRRRRLYKNVFKSEAWYFLNTNIDESDYRFQILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UST7</accession>
    <name>A0AAV4UST7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cuticle protein 14 isoform a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_446281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013388">
        <property type="protein sequence ID" value="GIY60872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UST7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044011264" evidence="4">
        <location>
            <begin position="18"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY60872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="17032" checksum="C1965D2D875A2161" modified="2024-11-27" version="1">MVLKGLIFVVLIASSQALPVLVASNALAETGASSQYKTEDNLGNYAFGYSEDHSSGGSFRKEAGDTLGNKVGSYGLHDADGRARVVNYVADSAGFRADVHTNEPGVDPTQDPADVTVNKAAVIVAPAVVAKTPTLLAPAPIIAHSHVHPTVTVLQPPLYHVHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXW3</accession>
    <name>A0AAV4UXW3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_583381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013660">
        <property type="protein sequence ID" value="GIY62747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14945" checksum="24709C1294211038" modified="2024-11-27" version="1">MQFLVNPTFHKLRKRGTCKNGKRAEFPPFLPGRNPPPSPSSSRTHPSPPEKNIPLILPMKPDRTLPYPPTLPIILSSIGLLPFPHPYTLFNPSSLPSLPRNTFDMSRRKIGIDFSPALPLAEKEERGGNRIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1M7</accession>
    <name>A0AAV4V1M7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_193523_1</name>
        <name evidence="1" type="ORF">CEXT_769301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013820">
        <property type="protein sequence ID" value="GIY64046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15638" checksum="1CEE318C3C4B49CA" modified="2024-11-27" version="1">MIFGIVKTTLWTSATSNNAHGFKNSGAKWRHRPTAVCRPGLPPAGVPLVPERDGLSVSPVRLGHRREMVGGTLILRNAEIRDSGRYICVLTSSGNEDRAETELVVTGNTDKWFCIWLSLFWVLQNDEWGFLLVLNESPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3G0</accession>
    <name>A0AAV4V3G0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Moesin/ezrin/radixin homolog 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RDX</name>
        <name evidence="13" type="ORF">CEXT_65391</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell junction</location>
            <location evidence="3">Adherens junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Microvillus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell projection</location>
            <location evidence="8">Rhabdomere</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013892">
        <property type="protein sequence ID" value="GIY64538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3G0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005902">
        <property type="term" value="C:microvillus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13194">
        <property type="entry name" value="FERM_C_ERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17187">
        <property type="entry name" value="FERM_F1_ERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000003">
        <property type="entry name" value="Radixin isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.10:FF:000002">
        <property type="entry name" value="radixin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000013">
        <property type="entry name" value="radixin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011174">
        <property type="entry name" value="ERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011259">
        <property type="entry name" value="ERM_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041789">
        <property type="entry name" value="ERM_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046810">
        <property type="entry name" value="ERM_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000798">
        <property type="entry name" value="Ez/rad/moesin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019747">
        <property type="entry name" value="FERM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018979">
        <property type="entry name" value="FERM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018980">
        <property type="entry name" value="FERM_PH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008954">
        <property type="entry name" value="Moesin_tail_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23281">
        <property type="entry name" value="MERLIN/MOESIN/EZRIN/RADIXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00769">
        <property type="entry name" value="ERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20492">
        <property type="entry name" value="ERM_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09380">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09379">
        <property type="entry name" value="FERM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002305">
        <property type="entry name" value="ERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00935">
        <property type="entry name" value="BAND41"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00661">
        <property type="entry name" value="ERMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01196">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48678">
        <property type="entry name" value="Moesin tail domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00660">
        <property type="entry name" value="FERM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="12">
        <location>
            <begin position="5"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="291"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="60"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)</name>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)</name>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR002305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY64538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="562" mass="66542" checksum="9860A877B282AB66" modified="2024-11-27" version="1">MPKPVNVRVITMDAELEFAIQPNTSGKQLFDQVVKTIGLREIWFFGLQYTDSKGLTTWLKLNKKVLNQDVKKENPLQFKFRAKFYPEDVSEELIQDITVRLFYLQVRNAKLSDEIYCPPETSVLLASYAVQAKHGDYNSEIHKPGCLANDRLLPQRVMDQHKLTKEQWEERIMNWEDAMMEYLKIAQDLEMYGVNYFDIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFFAPRLRINKRILSLCMGNHELYMRRRKPDTIEVQQMKAQAREEKLAKQQEREKLRREMEAREQAEKKQQEYAEKIKQMQEEMENRQKELMEAQDSIRRLEEQLRQVQKSKAELESKQNELEEMLKKLENDKAMEAEEKARLAEAIQMKQQEVMRIQEEVNQKDEETRKLQQEVEEARRRQEEAAAALMDATTPQHLNIHEDEHEENDDMVNGEFGAELSCDDSINLPKPEEERITQVSKEKHLQDQLKELSKELASSKDETKLTKNDLLHQENVRQGRDKYKTLREIRKGNTKRRVDQFENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5P7</accession>
    <name>A0AAV4V5P7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_687281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013995">
        <property type="protein sequence ID" value="GIY65472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5P7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="273" mass="30806" checksum="890991BF8900C542" modified="2024-11-27" version="1">MCAKFEEPLGACDFSDGVRSGDCWQSSPPKLQLFSQSICAIYDTFASLQWRRYQQCAHNTVTFLLDKLTDGEAISGIPLMPENYLKKVEILKDQFDHRGLGPIAERSHFFFFFEAVVVVFGTRPPTALLGWWGNIWLALQRLSPRETPSFLIPGATSPSKLLSGEAMDVYSSSESSAEKKDRDFQCRHLNFAFSGKFKRFKFYTMDLENELSNALRLDAPLNKGPVPRWQRKALENSVSSLSLNESNNDSTLINKSLNKSLKATATPKKLVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VA09</accession>
    <name>A0AAV4VA09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_436341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014211">
        <property type="protein sequence ID" value="GIY67176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VA09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10647" checksum="F6263A700D56C2F5" modified="2024-11-27" version="1">MSITSTRKLGTSKNGYKITQGVLNYTGSRSTWDTSVTRGADELAKAATLRTDVDHMVTFDTQVIKKLLKKKSWLNGNISGVIQLKEEKCSLYYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VB62</accession>
    <name>A0AAV4VB62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_526981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014252">
        <property type="protein sequence ID" value="GIY67537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VB62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12727" checksum="24403B62D4D41B0B" modified="2024-11-27" version="1">MDMESLVFIKSASSRRPSTCSCRQQDDRKHIIYSCTKWSHIRKVYFPPNHHDTKMDLLLFNKKSLQCLRLIIMEIKLKSSIQQSDYSHTWSSSAHLKYKKLSISPSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBP0</accession>
    <name>A0AAV4VBP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TAR DNA-binding protein 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tardbp</name>
        <name evidence="6" type="ORF">CEXT_72181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014236">
        <property type="protein sequence ID" value="GIY67419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12322">
        <property type="entry name" value="RRM2_TDP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000107">
        <property type="entry name" value="TAR DNA-binding protein 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033">
        <property type="entry name" value="RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033:SF9">
        <property type="entry name" value="TAR DNA-BINDING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="62"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY67419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="33362" checksum="B685526DC0E0B4EA" modified="2024-11-27" version="1">MLFYLLGKKDPKTGQSKGFGFIRFSSYESQARALSKRHLIDGRWCDVRIPNSKDGQVAELNRKVFIGRCTEDITADDLEEYFSKFGEVTDVFIPKPFRAFAFVTFLHPEVAQSLCGEDHIVKGASLLVSSAVPKNANANYHNRKSDNRAMNVNFPPNAAGFGPGHHGGNANIWNQPPYNMPVRGGDNIQNLAQLSTTLGLGNPNPNQGGGKGMNTTPPTLSMGALNLGAALPLSSAVVAAALNQAGLGLLGGITNQSSSEECPNPNVTTANPGNSNMGGNGCPTWMNQPSGNNEAIQWNPRDSKGYSMQVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBT7</accession>
    <name>A0AAV4VBT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_174697_1</name>
        <name evidence="1" type="ORF">CEXT_242721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014250">
        <property type="protein sequence ID" value="GIY67498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18575" checksum="56CA4E933152C4E1" modified="2024-11-27" version="1">MEEEYNDTSTGTLAPSLSKDKSGVDLLYATFWFYPSDTQGLLPEDKECIQSRLKQEKERFDPTNAFYGMDHDAYKDMVTEECLKKSGHLKNQKNSKKGYNPFNRQMGQMTVYRTHINCACPLINKTPHHKCAQILPFDEQMWPSYMGYYGNSVAKQRHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VM50</accession>
    <name>A0AAV4VM50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_232981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014701">
        <property type="protein sequence ID" value="GIY70669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VM50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12307" checksum="C884113DC4485CF3" modified="2024-11-27" version="1">MLLDEQKYLQWKDTETKFYFAKSGPFHSFKVRVSLPRRNRKLGGSVGWAKGVDEDTRSFREADSPNSLDSSEMGANLSPSSSTDLDRSGERIGWPSPLLIDKVIIDARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRE2</accession>
    <name>A0AAV4VRE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED17</name>
        <name evidence="6" type="ORF">CEXT_277361</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014996">
        <property type="protein sequence ID" value="GIY72837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY72837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="628" mass="70462" checksum="D260A21B795A70DC" modified="2024-11-27" version="1">MSVNVCIEAHQEYQVQEITYDGQEIYSQPLSMSENLTRLAHKIDFMKTDGDQQTSAESTEEESKELATFQASLWPWDSVRGKLRSMLTEICVLVDVLSIAKEKRYLILEPIPQDPPEPKPLIAVLQKKKALANAAAILMRGSERLRESQSETVRSRTPTDYHMELLQMRHAWRLKKVGNTILGDLSFRSSGSRYWQSGVFEVSKNEPSENSTPGPTPGCPPVRCNAIKVTLPNELEGFSYIHVSIQMDNEQISSGELTIPVSSSSLAQTEIHWQQKLEAAQNVLFCKELFCQLASEAVQMQSSIPNLVVGNQITTSLFPGVQLIIGLCHTTILDRAKNTVISAQAREHKPVLEHSLHQLLRELHYKAIHHPMPHPTTSGLGISKTRRLAGPEAADLETIRRSIDYETILEQIIKQTRHVVLRLRTMMIIDTFACEIKDPLIFTHWLSLSSPTLSSVKINIMTLGYETMCRTPLVIHVEEKSLKAICRDGRTMSLSYEPEELRYLLMCQASQHQVNAAQSLAKLMGWKVLSLGVNLGVGNVEPTGNASSVLMTSPTGDRVIALRCSPKNGIHVSVSFSPQTTDFYPSTLVRDRKWQNLGGSFREVMLEKMEGRNFLNKLEHLMACLTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUS6</accession>
    <name>A0AAV4VUS6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Voltage-dependent calcium channel type A subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cac</name>
        <name evidence="8" type="ORF">CEXT_698411</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015050">
        <property type="protein sequence ID" value="GIY73233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031649">
        <property type="entry name" value="GPHH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014873">
        <property type="entry name" value="VDCC_a1su_IQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08763">
        <property type="entry name" value="Ca_chan_IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16905">
        <property type="entry name" value="GPHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY73233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="28422" checksum="9A3F7C815F18388C" modified="2024-11-27" version="1">MDNFDYLTRDSSILGAHHLDEFIRMWAEYDPSATGQIHYTEMYDMLRNMDPPLGFGNKCPYRLAYKESVFTRKHAINPIGAYSSETTFSMNTKIDKLIRMNMPLSPDLKVNFTTTLFALIRENLSIKIRPIDEMDQADRELKETIRKIWPLQAKKAIDKLLPPEDDVAYICISKKLYGLGKYVTPSINFELPIPEQPSILSRLMGAVCNSNSRNSHVRCNVDNYYDDDKSQFSRSPRGSILQSNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VXR9</accession>
    <name>A0AAV4VXR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_65771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015276">
        <property type="protein sequence ID" value="GIY74933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VXR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8896" checksum="AADD05089AE1B59D" modified="2024-11-27" version="1">MVLFTKALEGNARAAQQLYRERFHREMYSNSSVDFFVWRALKAAVCATPIESEMDLVAIIADVAALFKKILGYLRAPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W447</accession>
    <name>A0AAV4W447_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_615371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015639">
        <property type="protein sequence ID" value="GIY77526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W447"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12120" checksum="8D2D2156B0054EC0" modified="2024-11-27" version="1">MNLGSSSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGSPSVRMNLGNPSIRINLIALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9A3</accession>
    <name>A0AAV4W9A3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase domain-containing protein 3, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ECHDC3</name>
        <name evidence="4" type="ORF">CEXT_594821</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015825">
        <property type="protein sequence ID" value="GIY78953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052377">
        <property type="entry name" value="Mitochondrial_ECH-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602:SF1">
        <property type="entry name" value="ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY78953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="331" mass="36286" checksum="90AAD7286381A5A5" modified="2024-11-27" version="1">MALFRKSKVLSSFLIRRCSNLSNLTIVSVDKGVKRITLNNPKKRNALSSAMLDQLERDIFDDAQDVNLRCIVLQSNGPVFSSGHDLKELYNSDQKTREEIFKKCSEVMVGIRNVPVPVIAVVNGLAAAAGCQLVASCDISIASSKSQFSTPGASVGLFCSTPGIAVSRNVPLKIASYMLLTGNNLIAKDAIQAGLISRMVEEQELEIETEKSEGSNVMVKNLSHKEAKEAYTIDVVSRTPTIKRPQESPTEGELAKYEENTSLFEINIGISKYKVGVLESYSDASHITGHSITGIVCWWSHFQTESKPVHSNHFSLQKEIVAVIKAVRELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLA3</accession>
    <name>A0AAV4WLA3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_522241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016327">
        <property type="protein sequence ID" value="GIY83034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7280" checksum="FC63E3FF540DE3B7" modified="2024-11-27" version="1">MDGSPHERGGRIIINCVTFDHSGGRLEERPVRLTMLGAQDSPFTKDRPQNENGAGGDCYYAAVADTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUX9</accession>
    <name>A0AAV4WUX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_199331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016659">
        <property type="protein sequence ID" value="GIY85485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20207" checksum="4767BBE37F223AE4" modified="2024-11-27" version="1">MEGNWWGRENAPGKIKKKKRKEKEVLAASNAKWRNHPSSFGECFPSLISLVFQNIWLRRVIFSFAQVTKTNPFRGVFVFSLQIEFDRFGKEGVGGRAGGGKGCNSTIWRGQVKKGGPNPLVPTGVEPPQQKWGGPNDLRKEDGNRISCSGQVRMPLVRSFPQRGGLIDLFIGGVGGRVRVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYH7</accession>
    <name>A0AAV4WYH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional repressor protein YY1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YY1</name>
        <name evidence="9" type="ORF">CEXT_715292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016948">
        <property type="protein sequence ID" value="GIY87527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000109">
        <property type="entry name" value="Transcriptional repressor protein YY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000163">
        <property type="entry name" value="transcriptional repressor protein YY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000174">
        <property type="entry name" value="Transcriptional repressor protein YY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="283"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY87527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="45525" checksum="2AD8512C97381D49" modified="2024-11-27" version="1">MASSDSFPDVQLGSGIHEVDLDGIPVEMPIETVETTVESVDDNPIISLALEPDDQDLILPDPEDIIVDVGDSEVYSAYDALSVPQQEELLETDPGTSKRSRKKSSKVKVDDDLSYEMERSSRRWAQKQIQIKTLEGEFSVTMWASGADEDETATSEPDPDFTEYMTGKKIPATGLPGVDLSDPKQLAEFAKMKPRKLSDDLSKTIACPHKGCIKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQFSLDFNLRTHVRIHTGDRPYVCPFDACSKKFAQSTNLKSHILTHAKAKGRKMHFTYVIAKPKASFLAKHIEALILELPATDPEVIGSFETVAISTLLFKDLISIRKPHLKKFWKVENCDFYTYFVNIHDKSSRELTNFKWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3D8</accession>
    <name>A0AAV4X3D8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_569431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017089">
        <property type="protein sequence ID" value="GIY88670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3D8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043955047" evidence="2">
        <location>
            <begin position="21"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY88670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="510" mass="52194" checksum="4AFB52941144A5B6" modified="2024-11-27" version="1">MILLQMLIFWAAMFCILIHSRGIANAKSLRRSPTDNVNAAKSSELLLKMSNRFKRSPQSGNCSMPTVEPANPDNETATNNTTSTTAVAINTTSRTTSVSSISASPTTSTTSIPFTSTTPIPVSSTTLTPLTSTTPIPITSTTPNPSTSTTSIPISSTTPIPITSTTPIPITSTTPNPSTSTAPIAITSTTPIPITSTTPIPNSATSIPITSTTPIPITSTTPIPVTSTTPIPITSTTPIPISSTILPVTSTTPIPITSTTPNPISSTILPVTSTTPIPITSTTPIPISSTILPVTSTTPIPITSTTPIPISSTILPVTSTAPIPITSTTPIPISSTILPVTSTTPIPITSTTPIPISSTILPVTSTTPIPITSTTPIPISSTILPVTSTTPIPITSTTPIPISSTILPVTSTTPIPITSTTPIPISSTILPVTSTAPIPITSTTPIPISSTILPVTSTTPIPITSTTPIPFLVLYSLLLVLPPIPITSTTPIPISSTILPVTSTTPNPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X538</accession>
    <name>A0AAV4X538_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fatty acyl-CoA reductase</fullName>
            <ecNumber evidence="1">1.2.1.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Far1_0</name>
        <name evidence="3" type="ORF">CEXT_690751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA</text>
            <dbReference type="Rhea" id="RHEA:52716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="EC" id="1.2.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the fatty acyl-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.84" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01017155">
        <property type="protein sequence ID" value="GIY89100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X538"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102965">
        <property type="term" value="F:alcohol-forming long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080019">
        <property type="term" value="F:alcohol-forming very long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026055">
        <property type="entry name" value="FAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011:SF45">
        <property type="entry name" value="FATTY ACYL-COA REDUCTASE CG8306-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011">
        <property type="entry name" value="MALE STERILITY PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="2">
        <location>
            <begin position="34"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY89100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="20890" checksum="142D3BA184E6C51A" modified="2024-11-27" version="1" fragment="single">MCREMSNLEAVGVLPWPAYSPDLTRIENVWSMVTKRLAVVHVSTSYVRKEPDNYVLEEIPKTKVTPKQILDAMQWMDEGAQEGVEDYLLEGKLTTYLVTKALGEIVVSQVYRDVPTSIIRPCNISRTFRDPFPGWCESIQGLSVLMLAGAKGVLRALMSVLDLKLNVVPVDLVANSMIVSAWHVAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDA1</accession>
    <name>A0AAV4XDA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_189349_1</name>
        <name evidence="2" type="ORF">CEXT_416991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017478">
        <property type="protein sequence ID" value="GIY91936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="30765" checksum="08101D6053F0C009" modified="2024-11-27" version="1">MEGLKSPMRSPAPSPALSPARSPALSPNRSPNKSPNISPGRSPSRASSNYGSPPHARHRSASIPVTPEALKGVRNRFLNAPGGLYPLGEANKDSTNLLKVEADSRTRLPRSAPELTVDEASPGSISPGMMTQASIPILWHTQCRDHRLRFYPEDSPRHLLALKKNSQYTWDDFRPRGNSVPCADPLLPKSRRASHQYVRRDRSVSPRPSLPFEMDDDKYYMLRQFCITSKGDVVNKGDLYRERSRSNNSVASTGSNVTGCASSATSCSSGQPSSAPPKRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEV7</accession>
    <name>A0AAV4XEV7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_560851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017634">
        <property type="protein sequence ID" value="GIY93163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10352" checksum="9F1FD44CABCB1F35" modified="2024-11-27" version="1">MFRSKQRRTSGWTNSTEGPVQRYYCIAANSTSLQEEDYCYFIASRISKKIFRVKTRRTSGWTNLQRTCTEYYCTAANSTSLQEEDYCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEY6</accession>
    <name>A0AAV4XEY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_97621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017585">
        <property type="protein sequence ID" value="GIY92795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9910" checksum="D47207E63EF95147" modified="2024-11-27" version="1">MPQLEQLEAHLPTGRQIFLTPTQFRFSEPVGAASLAKSVNNETAHTGPLDYCCDFSIQPRKRKTLTNRMFRFHGRLALSPLNPFPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJQ4</accession>
    <name>A0AAV4XJQ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized oxidoreductase ZK1290.5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ZK1290.5</name>
        <name evidence="2" type="ORF">CEXT_299361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017752">
        <property type="protein sequence ID" value="GIY94155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF10">
        <property type="entry name" value="ZGC:110366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10231" checksum="351F74EEDD7C6442" modified="2024-11-27" version="1">MPIFGLGTSHSGGYSQEAVVYALKNCNYRLIDTAKRYGCEEFLQSAIHLSGVPREDIFLTSKLWCTDYGSSTTRKAFQGSLKRLGVDYLGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMA4</accession>
    <name>A0AAV4XMA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_62901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000615">
        <property type="protein sequence ID" value="GIY96086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9828" checksum="B4662AAAB591E103" modified="2024-11-27" version="1">MESHQTVAEGKEGRVNSKSFRTRERRSAPNLVTQDEPLLAVIKFVPPQVPKRELMNTIHPSFSANYNLIRRSVEGLLAQMALQQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNK9</accession>
    <name>A0AAV4XNK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">THO complex subunit 5 homolog A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">thoc5-a</name>
        <name evidence="6" type="ORF">CEXT_737431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017899">
        <property type="protein sequence ID" value="GIY95343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="301"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY95343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="47907" checksum="0BF6BF786139F829" modified="2024-11-27" version="1">MSKKEKVEITTREKKAKRIKTHNARSNILSILPVNVDCFRLEEQEPAEDCYDNFLETCDKMRDYFRTICSAKRGKENETVAIKLRPHVCMLTMRLKKLNRLDKHQWKKSKDDVNEGKQRVDALHLQYQNLLYEVTHLQKEVTKCLEFRSMDEEIELVSVEEFYRDAPESISKPEITKNDPYELRMAQLIWETEQRKRYAERLKEVEITKQQYIKQQKALQENLDSILPILKSILHAAEPFQSKVGMPFQAMHTAHKLAKYLSQPLYILYVQISAYKEHHKGWKIEIDIEGNVDDVKGLQTKSEALSDESGESDREESTEVEMHRHKKKNENKKDILMKHPMTVILTIEKRYQKTGHIFELFISQRCRSRIAKSCKCLSNEKQIWVSEFEHFVNSIRFCSYFIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPV1</accession>
    <name>A0AAV4XPV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000690">
        <property type="protein sequence ID" value="GIY96688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8708" checksum="EE1A6255886656FF" modified="2024-11-27" version="1">MATDFHFSPDGFSEFSCRLRLVTPPSARPDTLCRRASKQLLVPLIRTSSESKKMTTMKRFPPRSTFTGFEQHNCVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRM8</accession>
    <name>A0AAV4XRM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CEXT_265481</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ankyrin SOCS box (ASB) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000817">
        <property type="protein sequence ID" value="GIY97677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045732">
        <property type="term" value="P:positive regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051573">
        <property type="entry name" value="Ankyrin-SOCS_box_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136:SF15">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136">
        <property type="entry name" value="SOWAH (DROSOPHILA) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="10" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="12" id="KW-1053">Target membrane</keyword>
    <keyword evidence="7" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY97677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15797" checksum="F3AB4EF26D6F8BDB" modified="2024-11-27" version="1">MNLITPLHYACEGGSVCWHRIAFQNGMLMFILLKVGLHLACINDKVECAEMLLKYGANINSLDEDKETPLHNAYFIGNIACTKLLLKMDANVHTHEGVTKPLHLSYLEDKGECAECYLNMEQISTSFVEEFVLLKDTCRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0L6</accession>
    <name>A0AAV4Y0L6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_496871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018595">
        <property type="protein sequence ID" value="GIZ00887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="30" mass="3433" checksum="B70B355BA5D9C41A" modified="2024-11-27" version="1" fragment="single">KAMKQKDWVARSPDLNPCKASVKWAIRFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y127</accession>
    <name>A0AAV4Y127_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_423771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001092">
        <property type="protein sequence ID" value="GIY99873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y127"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11531" checksum="BC9BF6829809142D" modified="2024-11-27" version="1">MRRQSSRPTRMFVDLNHLINSIPACTLHICVYYSISVWGHICVHYSISACTIPYLHILLHPCVYSPHLRLLLHICMYSLYLHVAIYACSTAYLHILSISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y237</accession>
    <name>A0AAV4Y237_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_531401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018620">
        <property type="protein sequence ID" value="GIZ01050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y237"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19316" checksum="A8B7C08999F1C2F0" modified="2024-11-27" version="1">MHMHMATYERKGGGINTRHSRSISHQNQRKESSLTTFSFGRRQGTQNGTYYIDIKRSALPTPLAFSSCCHKHLTFFFFHRRNLSKKIDKKRERTAPLGKVRIKKLYDAIKKKTAIPTDFGEISRFPRLPLPATTFRCTPRHGAFFCRWGRCVPAPPWPYTWEKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4R4</accession>
    <name>A0AAV4Y4R4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WASH complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Washc4</name>
        <name evidence="2" type="ORF">CEXT_650881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001229">
        <property type="protein sequence ID" value="GIZ00951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4R4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028191">
        <property type="entry name" value="WASH-4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027307">
        <property type="entry name" value="WASH7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31409">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31409:SF0">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14745">
        <property type="entry name" value="WASH-4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WASH complex subunit 4 N-terminal" evidence="1">
        <location>
            <begin position="30"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="25313" checksum="ACD698F33CA39D3D" modified="2024-11-27" version="1">MIVDVKEWDVDKIDDGVIKIVEEVQLRKYGKFLEGYSNQLRAIEHALDETLDDVWKYEIDPVSLVLLPKEKTSILELISTDNKVLNKIISVLAVLCCEVDNICSEAKRKYFPALLFYGEGEASDREALQDGEAHIYIGRMIPFMQELSCFIKHIYSVVKNIVHQLSALYNNGKNGVAVIDVTDVHFKKKSRGIELVCHGYAADRFCQSSIEDFYQGDPGHFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6Z6</accession>
    <name>A0AAV4Y6Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_722091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001570">
        <property type="protein sequence ID" value="GIZ03211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9434" checksum="7C1E08881AE0491E" modified="2024-11-27" version="1">MGLSAVKSPDDSTSTFFSSHSFSDAIDAVFKPFNSFLSIQLRSKGVEEENRTQLQCHISPFNEPPPSLEQDHSFCGNSISPRKKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8M1</accession>
    <name>A0AAV4Y8M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_585811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018929">
        <property type="protein sequence ID" value="GIZ03274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17475" checksum="10765DD5DE2ED552" modified="2024-11-27" version="1">MASGGKLCTNSTFLARTTDVPRLSNNLISEENGWFFDDDMEEKQKSRKAFSTSDLTPGISACHRQYVILQSKADGGSYTKRRDPLLELSGMVLQEVSIYEVLSLISSEMVMLWVIAERCGLKLSRISSLLSLISASTFPSRFINALARVINARCSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCD5</accession>
    <name>A0AAV4YCD5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_701731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019009">
        <property type="protein sequence ID" value="GIZ03880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10485" checksum="A5EC23AF2A2F3918" modified="2024-11-27" version="1">MNSDEATGILKEFSFSNSKGREEHILYATIASLRLSEVACMNKFPNGKREKNYGLFSFSSDNFYAVLVGLKCFKKCKFHKGRTNLASLCGQFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCG5</accession>
    <name>A0AAV4YCG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_337991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001637">
        <property type="protein sequence ID" value="GIZ03681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="13877" checksum="6CB8965A67D992D7" modified="2024-11-27" version="1">MTTSATTPASTPSQGSSAASPASGGSSGTPGTTSSGGSSGTPGTTSSGGSSGTPGTTSSGGSSGTPGTTSSGGSSGTPGTTSSGGSTKKSSAKTPAHAPTKGSSPASGGSSGTPASTSSGGSPMTTSATSPASTPSQGSSPVSSSGGSSGTPGSTSSGEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCK8</accession>
    <name>A0AAV4YCK8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Rpb10</name>
        <name evidence="9" type="ORF">CEXT_13501</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001692">
        <property type="protein sequence ID" value="GIZ04121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIZ04121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8702" checksum="46246BE258F84EBC" modified="2024-11-27" version="1">MLIVRQVANMIIPIRCFTCGKVIGNKWEAYLGLLQSEYTEGDALDSLGLKRYCCRRMLLGHVDLIEKLLNYAPLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDJ9</accession>
    <name>A0AAV4YDJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_304551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019087">
        <property type="protein sequence ID" value="GIZ04445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13309" checksum="DF4401DB9FE267A6" modified="2024-11-27" version="1">MTFYEKPGGSPGYLIVILHLHLVTMETNASQKKKTAHWEKDHKRMEQEITEPQESGNPLREEGKIERICDFWKRRSFLQKLTTTTATDKAEFNIRLTLFIEMVVKGNVGISFWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8N1</accession>
    <name>A0AAV4M8N1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_672641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001940">
        <property type="protein sequence ID" value="GIX68238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8N1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="342" mass="39493" checksum="A97DD44D7A8A3B41" modified="2024-11-27" version="1">MAEDQEMKFLVYQLIPNVMIETGTIETKQPLGIESFGNITREIIIHLTHAAAIKMHFNGETWKDFIIEKSSDFFNTEERYLSCVLYAVHIVNSRTGGIYERFIEVIATVLAIAHLMYDSNIKILEYSPQILTVFFDSVLKKLFYKRGGWKHLVKHIKSQNYMNCFEQISNLAPQPDNVTMEKAFEGTLESFKQNFRYEPVVVTPEELQNHALTAELVKKVMEAHEKDPPLHPCIFPNKEYDYIWSANIANSTGREALVLFTEDLEMEFVPLNYIRCKPLGSTENQQHFNCGIREDSEDLRLPEKCLLNTDAVNDIEGCILDVVDDIEYRFSTVKTLLDSLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBL3</accession>
    <name>A0AAV4MBL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_15611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002091">
        <property type="protein sequence ID" value="GIX69862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15853" checksum="4E3EA3D393432534" modified="2024-11-27" version="1">MKPRAAENRDFSFNSFLKTSWLQTNEWEEDASDFSAPVVDWGVLRPPWAVVCFRPGEAFSTPPVHPLQHLVSVMNSSHSVLNGTNAFLNRRRLRGCAVCVARQLPLKTRESSAIPVGCRRCPCSERFQRIRIEQGVGRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCN2</accession>
    <name>A0AAV4MCN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_747291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019551">
        <property type="protein sequence ID" value="GIX69161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8896" checksum="2C9211C5F614691C" modified="2024-11-27" version="1">MPDETSPSRPPGNQIVITIPDGPAPPSGMHVNHPLHRDAPRINGLLLCLLLVFSWKWFSPSRTDVRLGKTSKELFLWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHY0</accession>
    <name>A0AAV4MHY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Midasin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MDN1</name>
        <name evidence="4" type="ORF">CEXT_92061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002223">
        <property type="protein sequence ID" value="GIX71475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="332"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="458"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="483"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="625"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX71475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="648" mass="73303" checksum="C6E9A39E1C8D4AC2" modified="2024-11-27" version="1">MPSLISDQNLLCSFVKDDLKWTAVVKCINESSAELENHFQRMCNSASNTSMFTTWERFSQTVENFKILMMSVYTVGNTIRKPGFKREQHPTLSLDRLSDKVQKEFLKAQERYNAIHYKSKIKGTQDCTKNITFNNIVQKLTKEVLLAYQDVVALCKSSNEINVSDDMCPENLFTVRITACMSDFEKCLRFQTITKLLNRLKKRIQQNMTSLEDIKAINDSLSPPMWACPLVNLILITLNLTPVLNQYFQLVKVYLAVHLGMHRTSCKFLTILLEIFNRLATKGFCIPADLEEEAKKSDETKFEDFEAGGFDDGEGVKDVSEKIESEDQLEGASKEGQEKEENKDQNDIKEEEKGIEMSDDFEGKSYNPDEKQEESEGSDNEEGNEDLDKQMGDVDTEEAEKLDEKMWGSDSEDEEEDLNDANDTGGVTENRPSELVAKDDMKKDSDNTGKKDMPQETLPDEQNDEYQGEAPDPLIDAPVQEPEVVELPEDMEITDDVDKEDGDGDEEPEEMEMEFVSDEDLESKEVSEETEEDTEKSDAENNANKTTQEEENITKSDSAELAEENDDTNDKTIESNLPTHSSTAENEALPSEQTQSNSEDPVQEDSDKDWEGSGQRSDEQHKGQSETNNPSDQSAANESGATTKKEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLC2</accession>
    <name>A0AAV4MLC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019865">
        <property type="protein sequence ID" value="GIX72660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7436" checksum="87362AE7533E55F0" modified="2024-11-27" version="1">MNLSLTSVDIGSVHLPSNLSVGNNTFCKKQVERGVLAVSARNLESFLRPNKLLANLHYVESIHCRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY39</accession>
    <name>A0AAV4MY39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_318431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020284">
        <property type="protein sequence ID" value="GIX76860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9902" checksum="EF8E680F5BEC2705" modified="2024-11-27" version="1">MNAFDETALSVFIEAALNVFDKTVMALFNEATLNVFDKKVMALFNETALRAFVETALRAFVETALRVFIETALNVFDEKAFGALMKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5Z5</accession>
    <name>A0AAV4N5Z5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_82411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020535">
        <property type="protein sequence ID" value="GIX79789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF193">
        <property type="entry name" value="CYTOCHROME P450 4V2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX79789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="19724" checksum="E3EA22175BE2BFCD" modified="2024-11-27" version="1">MRYRRRYTKSWTVYWELTSKGPISIGDLNELKYLDCVLKECYRLYPVAAGFGRKISEDISICGYKIHKRAHVIVAPFFLHRDEDVFPIQRNLIQNDFYRKTGRIFLIVRTFLLVRDRETALRSENPGVSHSEKLLPSLSGLEEPSASHYQNQSPIVSNPPASNFDVDNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7Q9</accession>
    <name>A0AAV4N7Q9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KAT8 regulatory NSL complex subunit 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">KANSL1L_1</name>
        <name evidence="2" type="ORF">CEXT_284091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003068">
        <property type="protein sequence ID" value="GIX80872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7Q9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044545">
        <property type="term" value="C:NSL complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035035">
        <property type="term" value="F:histone acetyltransferase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026180">
        <property type="entry name" value="NSL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22443">
        <property type="entry name" value="NON-SPECIFIC LETHAL 1, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22443:SF18">
        <property type="entry name" value="NON-SPECIFIC LETHAL 1, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="632"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="892"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="979" mass="108983" checksum="CB5DD7BA838DC005" modified="2024-11-27" version="1">MAPALTKADRRADCLPVVLPFCVSKTADPENRKDNDYNLAKFQKIACWLNKRKYMNKAWFRAYVRNTSELSDKNRYSQIDLRKSLLSSKLRINAEARNKSWHGTNVTLAVADKVRLKYTMNKNNNSIRNMGLARANTSLGLHSMKKMNRITQLPHRDKGNPSNLTHELGESSPELPDPANVELETPYRIVKLVQGTEELSSSSDLNCNMAPSKENALSTTNNQSSDIVSVSVNSDVPLSISPNDVEASLCDSNLSVILTDSKCSLNTAKNLDSGIVKLPVPETNSIQLLLPEVEDTPVSDIESKATSVIEEESLVLPHLSNEDIIQEASNFKDSELHDSSVDHLNCIASLPSPLCDVHVQDDIADITASLEARTSPFSIPSPCSPSRLFNDGSDVESDSLTSSTLSADASPIPSSVEEGVEKVFITFPDSFLASPSGVHKELAAPAFSDVACLSIDNSDFIGSDDEMHIMRKTCCPPADQDLSFFRDRLIEHERKISNTLKETEALLRMHSMDHIHQQIRSFVQHFQKKLMIPCQRQHKMGISKNNRNLVDLKAELLQNEDVKNLSTAALVSLVRTWSNPSTGNLPPQNAILQDSELRNKLISTFTPEDIDDVKNASKIFLKNMKKLLRSADPELTESSDDGSSDLEQSEESPAQKKALWKFMKQRAALASRATLLTAKIRELENQLRTVAGYLTKVNSSYGDLRFENQRTSTTSTLPIFVSESSGDVSLESAMKQNKPKSLNRPVNGYLDHGPINNTIHVGTTNSYTSVCLEQKLSNRIDAEDTCSRTRALKTSNFHKRKLLVTTGLHLTNPKSAKLSTVNCVCNCQDAILPCILCTGRYNCIQSVDPDSMPLLDRVALLDPPFHPHLSFEKDISLLMHFENILKKNEAQYQSERSASPSSHRRLSLGTKQRHLNDTKSHGRKLKRYSHLSEKVKYRKRRRNISGSINLCLESGGNFKIKFMPEIVAGLSSCIKLQFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7W3</accession>
    <name>A0AAV4N7W3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_431201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020631">
        <property type="protein sequence ID" value="GIX80905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7W3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11882" checksum="5EEF891BEC2A9E8F" modified="2024-11-27" version="1">MGGGNPTRQQISFLLFRSEEMSVDIDGDCGSIIDIADGRRKPYKATNQFPSFQKRGNDRRHRRGRNSMMENERKGAPGQGLQSANGLKTEREIEISLMLFLRGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N948</accession>
    <name>A0AAV4N948_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020629">
        <property type="protein sequence ID" value="GIX80869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N948"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14906" checksum="4CF85411500915ED" modified="2024-11-27" version="1">MPSYLANATSCRIYIAPPDDDVGILQWVLCFCSAINPDSKTKKVEMSRWLLSSPELNSEILHDVYGEGKIPSCLANAKSCRIYIAAPDDDVGILQWVLCFCSAINPDSKTKKVEMSMASVLSRVKQCRQMVQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NA56</accession>
    <name>A0AAV4NA56_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cdk14</name>
        <name evidence="13" type="ORF">CEXT_734901</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01020658">
        <property type="protein sequence ID" value="GIX81214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NA56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07844">
        <property type="entry name" value="STKc_PCTAIRE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000131">
        <property type="entry name" value="cyclin-dependent kinase 14 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000007">
        <property type="entry name" value="Cyclin-dependent kinase 14, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF246">
        <property type="entry name" value="ECDYSONE-INDUCED PROTEIN 63E, ISOFORM N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="15"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX81214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="337" mass="38375" checksum="23C383550F541218" modified="2024-11-27" version="1">MEDDPSLGFGRSESYIKLEQLGEGSYATVFKGFSELNNKVVALKEIRLQPEEGAPFTAIREASLLRGLKHANIVTLHDIIHTRETLTFVFEYVHTDLSQYLERHPGGLHPRNIKLFMFQLLRGLAFCHQRRVLHRDLKPQNLLISEVGELKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLLGSTNYSTSLDMWGVGCIYVEMITGKAAFQGMKDTMDQLDKIFRVIGTPTDDTWDGVSQFPNYKPQKFGHYQSQPLSAAFPRITEICQGENLAYSFLQLQPRLRISASEALRHTYFDELPPKIYDLPEQVSIYTVSGCKMSPETNNQTVIKIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBW0</accession>
    <name>A0AAV4NBW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_245944_1</name>
        <name evidence="1" type="ORF">CEXT_224041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020678">
        <property type="protein sequence ID" value="GIX81441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14205" checksum="7E1E499B4542B046" modified="2024-11-27" version="1">MFNHMPYSSPAASQHSNYFSNAPIPQPTVPRFPIKDMFQGAFSQYPSKPSFLNKIKPYLFGNTGPRSLPHDPYYPNIFSSSPIHSKWPYHNRPPALSFLSVSSNAPFSCHDETRKSPVLALCMLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NF78</accession>
    <name>A0AAV4NF78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003334">
        <property type="protein sequence ID" value="GIX83469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NF78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12379" checksum="5EB0F31BBC98D5BF" modified="2024-11-27" version="1">MKCSILISNNIKSSMEVIHYSHAISRFFNIKQGLPVHNSMLYPHYTSVLPVKMIISCLFYERRKGCHSFSRGWTFWCHYNFKQVSPRTIYEELSPSSNPIEAHPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFW1</accession>
    <name>A0AAV4NFW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_398071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003356">
        <property type="protein sequence ID" value="GIX83672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11331" checksum="02C0CA60F94414BA" modified="2024-11-27" version="1">MICESPEIELQGDVKWHLPPACSDQRQEQEKATASGRMCRRHPRLQLLIRLLHRNPAFRLISQLATPARLSSSTCLTTSRRHTLGLRTLLALLLAWNHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGP3</accession>
    <name>A0AAV4NGP3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_52511</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020818">
        <property type="protein sequence ID" value="GIX82886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="200"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="229"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX82886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="492" mass="57013" checksum="703BA0F7224D2BF0" modified="2024-11-27" version="1">MAPGIADKKNNTLPLWGNDKTMNLNNLILTNIQSSHYFKVNLYQLKTYHEVIDEIYFKVNHLEPWEKGSRKTAGQTGMCGGVRGVGAGGIVSTAFCILYKLFTLKLTRKQVVGLINHIDSPHIRALGFMYIRYTQPPADLWEWYEHYLDDDEELDVKAGGGQVMTIGEMLCHFLSKLEWFSTLFPRIPVPVQKDLERKLSNRRANAKTSIAIVPEESEPAEPKQSVQNHWEEEGHSRRNSSRSRDSGKNAKDSRSRDEITEDAGKERDRSRRERHDKSSKHHHSSSKRNKHSSRRSTSNVNKHARHRTRSPSHENYKYSSHRVRSQSPSSADYRHSNYRTRSPVELNSRSSHRVQSRSPSSADYRHSNYRTRSSVDRDFGHTSHRTRSPVEVNSRYSHRVCSRSPSSADYKHSNYRTRSSAELDSRSSHRMRSRSPSSADYKHSNYQTHSSADRDSGHTSYRTRSPVELDSRYPSHRSRSPVDHRHRNHHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJK6</accession>
    <name>A0AAV4NJK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein arginine N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PRMT5</name>
        <name evidence="1" type="ORF">CEXT_151261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003434">
        <property type="protein sequence ID" value="GIX84529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8885" checksum="50DFCEC96D0FA608" modified="2024-11-27" version="1">MPTREHISCGVFYHNVHDMYDSLGNASQAGYNFIVAPIVHPRFRREFFAGKARNRLGAFTRSDLVLSTQGIVLVRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK39</accession>
    <name>A0AAV4NK39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 4V2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Cyp4v2</name>
        <name evidence="11" type="ORF">CEXT_440501</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020992">
        <property type="protein sequence ID" value="GIX84690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX84690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="33020" checksum="7008BD693E2D7CE9" modified="2024-11-27" version="1">MYRILRPYLYPDTIFRLSSTGRKFFASVIKDKKAEIIANRKLNPIVETAPDGSPMLRKKRKAFLELLMEYHLKDPTFTEEDIREEVDTFMFEGHDTTAMALSWALYSLGSHPDIQKTAQEELDGIFEDDMERDIRREDLPRMKYLECVIKEALRLYPSVPLIARKNKQPFKVLNYTVHAGSLCVIFPQALHLDEGSFPDPEKFNPERFFPENSTGRHPYAYVPFSAGPRNCIGQKFALMEEKTVLASILRKFRITSLDPRDKILQIPSMVTRSILPLRVRFEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNK2</accession>
    <name>A0AAV4NNK2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcription and mRNA export factor ENY2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Enhancer of yellow 2 transcription factor homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ENY2</name>
        <name evidence="12" type="ORF">CEXT_327591</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ENY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003562">
        <property type="protein sequence ID" value="GIX86033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071819">
        <property type="term" value="C:DUBm complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.140:FF:000001">
        <property type="entry name" value="Transcription and mRNA export factor ENY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03046">
        <property type="entry name" value="ENY2_Sus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018783">
        <property type="entry name" value="TF_ENY2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038212">
        <property type="entry name" value="TF_EnY2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12514">
        <property type="entry name" value="ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10163">
        <property type="entry name" value="EnY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0010">Activator</keyword>
    <keyword evidence="4 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 11" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX86033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9914" checksum="1AB0B54024E0153E" modified="2024-11-27" version="1">MQEKFTIESAEEERLKELLRTRLSESGWKEEMKAVCRDIIRDRGVENVTIEGLVKEMTPKARELVPDSVKRELLQKIKIHFEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNW5</accession>
    <name>A0AAV4NNW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_562001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003489">
        <property type="protein sequence ID" value="GIX85229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12263" checksum="2E62F019E03BC563" modified="2024-11-27" version="1">MSTNLLSPVIEVLQAVLEEVAIRDARHGQPGNQCSVSVPMSTLECSRGVPRRRAEGRVLRGNAQKTSVASSLSPICLHRMLASHPKQTSQPPVPTQNASIVFNHSTGNLSHCTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSR9</accession>
    <name>A0AAV4NSR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_227371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003636">
        <property type="protein sequence ID" value="GIX86976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20812" checksum="082FC12E882D5FFC" modified="2024-11-27" version="1">MLLKTLKKSNLCYFAQQVAPNRKQTPNASAFAKYSVLKTALESVPVSEESVAFARILHHCRRNLLRDTNAECHLLLRLRQEKKLRWWPICRSFRLDASFHLPQEKSSGAFDAVSDLFPRICFRRISPDHTSSEKRGLMKMMMHIMWDPPSVSSGTGMHTTSPKRSPKLAEDHTNHVAIAFPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P338</accession>
    <name>A0AAV4P338_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_122867_1</name>
        <name evidence="1" type="ORF">CEXT_201391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003878">
        <property type="protein sequence ID" value="GIX89622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P338"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="326" mass="37615" checksum="55C082C56EFD9FD3" modified="2024-11-27" version="1">MDLNGFVNTSNDDSKCISVAFETFGGKIYNNACKNGNNLMTVQTLKCRTMAYVMNLLGISWDMLKNITLNYTPVHPQVAQELFRLVPNDDKIEYLLSQDFIRNNELFSIMKKLNRNERDKLAAVDGLVGVDSSSGPNFDFKRYSENLSYSMDGSPGFFNDDKERGLKGKHVQAIRRMYCEMHRYISAERLAPYVYRVVRQVCEELGGPTLPKIENEPQMSDNVLLGCKNIYVETMGQVEARKFMENIKVKLHKKDNEPTAHMSKNEKEWSVLLTKRLINVEINVCEKCLVNLKTVGFWLYRKLLSLKNLSAQRILKKKKKKKKKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PF49</accession>
    <name>A0AAV4PF49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_659521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004549">
        <property type="protein sequence ID" value="GIX95668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PF49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="25968" checksum="891D8D0B0DE604EB" modified="2024-11-27" version="1">MNSKHIPGNVKADLLMTEEEPVDYRVLDKPAYPDIINEDQNNIDMLRDKICIDNQQVSGIMNSKHIPGNVKADLLMTEEEPVDYRVLDKPAYPDIINEDQKNIDMLRDKICIDNQQVSGIMNSKHIPGNVKADLLMTEEEPVDYRVLDKPAYPDIINEDQNNIGMLSDKICIDNQQVSGIMNSKHIPGNVKADLLMTEEEPVDYRVLDKPAYPDIINEDQNKYRYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PG37</accession>
    <name>A0AAV4PG37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_280791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004453">
        <property type="protein sequence ID" value="GIX94940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PG37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9698" checksum="6C233E89AB84CE32" modified="2024-11-27" version="1">MPPELFHHGSVPPQKLLTTHESAHLFESLDRNIVLKSPPRVFPWKSDEIVSGMGDILLCYSSCVIRRHLLSLPAINAMALPTQEDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLB5</accession>
    <name>A0AAV4PLB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_411281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004737">
        <property type="protein sequence ID" value="GIX97103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13355" checksum="DC66F2E2D9125AEF" modified="2024-11-27" version="1">MELFREADSKGPLNEDLEKQEREEIQFSTPSERNQGKRGMINYKKQTHRPGSKIKSLTASTVDINRQIREMISSRCPQVEREPNRRNKYRLTVSEDSNKLQESCGHNCWKIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLL6</accession>
    <name>A0AAV4PLL6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adult-specific rigid cuticular protein 15.7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_500301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004764">
        <property type="protein sequence ID" value="GIX97305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043932511" description="Adult-specific rigid cuticular protein 15.7" evidence="4">
        <location>
            <begin position="18"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX97305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="15042" checksum="7F063433C1859977" modified="2024-11-27" version="1">MIAKVAILFAALAAVHANVLLGGHGHLVNTGVSTSARTQDAFGNNAFGYTIKDGLGATNSRSEVGDGYGNRKGSYTITDIDGRARRVDYVADGHGFRATVKTNEPGTAASAPAAALINSPYAGPVAPVVNHVAPAAPVVAAPWPSPHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PP34</accession>
    <name>A0AAV4PP34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_559721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004967">
        <property type="protein sequence ID" value="GIX98836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PP34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17557" checksum="46955A8198E10DEA" modified="2024-11-27" version="1">MMAGYSISTTSPMTARESFCCQSIDGRIFSFLYSPSVLGLMYPSALHLSNDCQRIFCCQSIDGLIYPSGPPYDCQRISNPLHAEIFCCQSKMAGILLTINRRFPSVSLMYPGIPLANDCQRIFCSSINRWRIFTRNCHVAPNDLGVVQCQYSRQMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PT08</accession>
    <name>A0AAV4PT08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_175361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005154">
        <property type="protein sequence ID" value="GIY00184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PT08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17510" checksum="7174414473CCA509" modified="2024-11-27" version="1">MLATFTNPSAESYLFFFGALLFFRLEELLAVLCLIDNGWCRSQRQVHIHVRSRRQIGNISRGRRYYTRALRRAFPCRVNTTVVINFHLQNLTFTETASSKNDHRPLSNQLSKTEYIDLPQVSDPIRIDRAKLISTSFEHFSSAKPIFSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0M3</accession>
    <name>A0AAV4Q0M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_760961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005514">
        <property type="protein sequence ID" value="GIY02872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="11010" checksum="FD01D685F88E21AB" modified="2024-11-27" version="1">MPLWARPIPSFSNNGNTDEMFLSWESFQLFYIFPPRTKYPLYPKKETIPAKCFPQTAFRSKFLLLLFLAGKRFPLDILMPRNDRQLKRDYCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q337</accession>
    <name>A0AAV4Q337_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable arginine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_485221</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the attachment of arginine to tRNA(Arg) in a two-step reaction: arginine is first activated by ATP to form Arg-AMP and then transferred to the acceptor end of tRNA(Arg).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01005663">
        <property type="protein sequence ID" value="GIY04063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q337"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF11">
        <property type="entry name" value="ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR anticodon binding" evidence="12">
        <location>
            <begin position="422"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY04063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="537" mass="61722" checksum="05F4386D7F7B658F" modified="2024-11-27" version="1">MTSVFRRRITYQIINTLNPYLKKEDRAIIYDSLPLSLKLSQPKHLPPQFEFSWKKIVKLKPELQDLVHPNTLTTYLKIRYYEFPIDGITDILTDSLTEEKLIFTVDQNQFSANVILNIIKNIENIPSWSCFFRNIPPENVIVEYSSPNVAKPFHFGHFRSTIVGNFVANICKYVGHKVTRLNYVGDWGLQYGILAVGFNKFGCEKELQKDPLNHLFEVYKQANEQNESNPSFNEEAKMYFKKMENGDADALALWQRLRDLSLKEMNATFIRSQGIASCNEDGSIEAIIAEENDKVEKAVLRKKDGTSLYLTRDLAAAIDRWKKYHFDSAFYVVDSTQRSHFQHLTHILKSMGYSWADEARERTLEGMRNSPNTKVTENLEQIAGVLGASSLIVNDFSMRRKRDYPFNWDKILNMKSNSGITLQYCHARLNNLKENCGIDLSMGCEFSYLSEPEALSLIHHLAKFEEAAYFAYTELEPCVLVHYLFSLSQEVGRALKALKVKGSHPCIAEARLLLFHSAHLVMRKGLQLLGVTPLDKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7J2</accession>
    <name>A0AAV4Q7J2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nrf-6</name>
        <name evidence="5" type="ORF">CEXT_64011</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005784">
        <property type="protein sequence ID" value="GIY04981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7J2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006621">
        <property type="entry name" value="Nose-resist-to-fluoxetine_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF0">
        <property type="entry name" value="O-ACYLTRANSFERASE LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20146">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00703">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043461585" evidence="3">
        <location>
            <begin position="28"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="724"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="751"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="792"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="829"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="871"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="903"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="933"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="Nose resistant-to-fluoxetine protein N-terminal" evidence="4">
        <location>
            <begin position="362"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY04981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1004" mass="113148" checksum="E5F98556AF5E59DF" modified="2024-11-27" version="1">MVAHKKIILKWGALFILVALKIDSVASRTLIDSEQDRTTNSSGALRDFPYSSEIVPSSSSFHHANTTMTHRQSDIPVSVQNEDRNSSFTSPNTDDPLEITEISNGSSVNTMKSVPKDELTMSYDNQHAVQDEMSNHFKTDSLQNSSHVLSNEEAVLDEVLNDSIESIPAVVDIEESNTTMVKVVIEHFGKNIKKLKENVHSFKDNLRKILFETDTHMSSKSPENHTMPSTSIHVEESSENKHNEHGNVTFQHQSIIEECQERGGSLELNKISAVASNISEVSRRVGAFLQDHYWDSNKDQKQSEMISRGLENLVGGVEEVVPSSQVLQQWVNLEESFRESVDAVVRQALPLLVRASSEMQLSNGCYTSFFQLLLGLRRLRPWAFQMIDAFGKPPAGMLQGTVTSFGAYDECVNIVAASDAKKYSQQYFRGKYCTVEIKPPLPPKPQYYTMYQPVSILANFSNGDDNVIRQAARQAHAFYFLTYRMDICVPSTCTQEDVNNMAQFAAKYIDIEVTVPRCSVKENLHFDKTQVITICILGVLVLLVVFGTILDILKEMFNRTKFIIRCLSSALFKFLRSFSLNTNANLLLNTDSAQNGLDSVHGMRFFGMGWLILGHTYFNSNIQMYGNLSEASAFAEGFFFQIIVNSTVSIDTFFFISAKTYKDPPHLHDGDQRHLHPAASRFGPLLERDRRPRGGLLQAELVDQPPLHQQLHHHSRQRCLEHSWYISCDFQLFVIALFILLALIKRPVFGMVLNIMMIVVSMVTTGLLTYYYKVPPTLLASFPDPEERKFLNHVIISKPFCHLGPYCVGLATGYFFYKCKEIKLKPYHHIIGWGSAISVTAAVVYGVLEWNKGHLPSTAAALAYAATHRTAWALGLSWITIICVAGYGGLINSILSWKVFIPLSRLTCMVYLIHPLIQYILTGYIRERLQTNHIILAYFFFGHIMTSYALSAACFFLFDGPVEALMRLILGDYTAPIPELAKTSAIKKVLNNNIYNEKKSNLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q818</accession>
    <name>A0AAV4Q818_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_243151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005591">
        <property type="protein sequence ID" value="GIY03528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q818"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13323" checksum="CE7A9056C15E8A5B" modified="2024-11-27" version="1">MEERMDGRKSGWTNGWMNEWMDLRMDGWMNGWDFRWMDGRMGGWMDGWTDGWMDGRTEGRLRDGWMGGRMNGRMDAWTGGRMVNGWNVNAEMGQKSSAVLKTHYISNGNCKIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGT4</accession>
    <name>A0AAV4QGT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_82361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006203">
        <property type="protein sequence ID" value="GIY08116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19611" checksum="1F902594C000CCCC" modified="2024-11-27" version="1">MEAGELLRVEFEQTYLNLEPNESSSTIPEEVHSNEPPALTEKGAFRSHRRSSTLLLRGGGASDKSRLLFQFLQRGRRLPLGEGDAGGVHQGGPSPWPRPPTSCWVTPPSTWPLSTASRERKRGRRTNGKRRRTGSSGSLSPLEYWRTRRRSWTRSGTRGAKSKGSRMCQTSWSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QK56</accession>
    <name>A0AAV4QK56_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="4">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Formylglycinamide ribonucleotide amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Formylglycinamide ribotide amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">Pfas</name>
        <name evidence="23" type="ORF">CEXT_694691</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="17">Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01006245">
        <property type="protein sequence ID" value="GIY08435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QK56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01740">
        <property type="entry name" value="GATase1_FGAR_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02204">
        <property type="entry name" value="PurL_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000010">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000008">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000007">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000028">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.750:FF:000001">
        <property type="entry name" value="Putative phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.750">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055181">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003672">
        <property type="entry name" value="PRK05297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22689">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13507">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01211">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109736">
        <property type="entry name" value="FGAM synthase PurL, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="PurS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase N-terminal" evidence="21">
        <location>
            <begin position="41"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase linker" evidence="20">
        <location>
            <begin position="147"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="19">
        <location>
            <begin position="448"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT PurM N-terminal-like" evidence="22">
        <location>
            <begin position="598"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="19">
        <location>
            <begin position="783"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00057317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00071729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF22689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="GIY08435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1251" mass="137709" checksum="675C09A31622FF53" modified="2024-11-27" version="1">MLLQFFVTPALSDHKLNERRYNLNQNLTKLNVEIEEIKTEFCCYVEVERLLNDDELPKLKWLLQSYGTELSNNSNFADFSEGTKKQFAVEVGPRLNFSTPFSTNAVSICKSINLPVSRIERATSFSIDFTPTPWEEVDILGRGRDALEEVSINLGLAMDNWDLDFYTRIFREELKKNPTTVECFDLAQSNSEHSRHWFFKGNMIIDGVPMKENLFEMIMKTQKHSNQNNVIKFSDNSSAIKGFNIHLFSPVDSDQPSYFKTRSGVRHIIFTAETHNFPTGVAPFSGAATGTGGRIRDVQAAGRGAHVIAGTAAYSFGNLNIPGYDLPWEDKTFEYPSNFALPVDVAVEASNGASDYGNKFGEPIILGFARSFGMKLANNERREYIKPIMFTGGIGSIDEKLIKKKDPEPGMLVVKIGGPVYRIGVGGGAASSVHVQGDQKEELILVHIHDQGAGGNGNVLKEIVEGAGAVIYADQFQLGDPTISTLELWGAEYQESNAILVNPKDRDALQNIGDREKCQISFVGEVNNSGDIVLVEKRDEDVPRHPVDLKLSCVLGSVPPKTFHLNRQPSVFRNLELPTTLKLQEALDRVLRLPCVASKRYLTNKVDRSVTGLIAQQQCVGPLHTPLADVAVIALSYWDTVGSATSIGEQPIKGLLNPAAGARMSVAEALTNIVFARLSCLQDVKCSGNWMWAAKLPGEGAALYDACKAMCSIMGKLGIAIDGGKDSLSMAARVSNETVKAPGTLVISAYAPCPDITLTVTPDLKCPDDKGILLHVNLSGGKARLGGTALAQCFNQLGAEPPDLDNPISLKESFNITQKLISQRKITAGHDISDGGFLVCLLEMAFAGNCGVNVNISTNNSLFETLFNEELGWVIEVNENDMEYVMNAYKNKGINCHSIGFSCNQSKNSQIVLSVNSEIILNQSMVLLREIWEETSFQLEKRQTNNICVEQEKNGLQKRGTPEYSLSFDVSPLQLCNLWKPTGPRVAVIREEGINGDREMNAALFMAGFTAFDVTMTDLLTKKVTLGKFQGVVFPGGFSYADVLGSARGWAASFLFHPDIEAEFAAFKNRSDTFSLGICNGCQLMALLGWIGSISDEDKLTQSVTLSHNVSERFESRFVTVKIVNSPSIMLSGMENSVMGVWVAHGEGQFKFKNSDVLNYIKSKNLAPVLYVDDHGVPTTEYPLNPNGSVDGIASVCSADGRHLAMMPHPERCVLPWQWAWMPEEWKSSMTTVSPWLKMFVNAYDWCCRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSS8</accession>
    <name>A0AAV4QSS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_461191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006618">
        <property type="protein sequence ID" value="GIY11192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="21301" checksum="91C26FC477675FD0" modified="2024-11-27" version="1">MAVPQNSHFAMSRERQGSREEGGGAEMPRREPEQADNWRDADKSNKGKRHRFYFIFVPIIFPFWEPTNIYHSNKSLSKPRSGYPQHSFPPYLNTALGYYNPLKMYIASSTKCFCQISELSWGSLFIFESFVKCNEQSTSFCSCVFEKPYGNDGRKSEVTVFRDILGIPKGIHWYLKTLRCVAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QY40</accession>
    <name>A0AAV4QY40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_732781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007051">
        <property type="protein sequence ID" value="GIY14170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QY40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10016" checksum="CAA9C622C2DF820C" modified="2024-11-27" version="1">MTKGPRPSSMNPAMFINTHLEVCNENSGLKNMGSLFPILTIASKLSKNSIPQNNGSRTTSPENERRECPKGGQPFYQTTINSGGRRVEAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZ05</accession>
    <name>A0AAV4QZ05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_646741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006960">
        <property type="protein sequence ID" value="GIY13569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZ05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8801" checksum="50889132A86028E8" modified="2024-11-27" version="1">MNRTSTFQSSTFPQSTTQERHWDVNSTATTDVRYALSNAVQNKNFDYFKSSRGSLIPAAQYFENSACTSGVENLPNAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1X9</accession>
    <name>A0AAV4R1X9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_587641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007240">
        <property type="protein sequence ID" value="GIY15490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11269" checksum="524285FC06812A34" modified="2024-11-27" version="1">MKDMKFARMKGNGEGINNSTKKGKKAVELHTQDKNVNTGSELLLLHKLGLWLFVTNNSSVHTPRRFMTASCFWSTFYTMGIRICSTRQGKINEWQNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4C1</accession>
    <name>A0AAV4R4C1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sodium-dependent glucose transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MFSD4B</name>
        <name evidence="5" type="ORF">CEXT_809421</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007171">
        <property type="protein sequence ID" value="GIY14928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4C1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23121">
        <property type="entry name" value="SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23121:SF9">
        <property type="entry name" value="SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY14928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="228" mass="25087" checksum="C290F4CE293F11B9" modified="2024-11-27" version="1">MYQIKTSLINPAGITTKRKYRSAGCAFGNIAGGVIFDALTRTQMVLTVFNLSTALTMLSIPWSRSMEVLTVLMTINGISLGILETGSNVCCLSLWGKDSGPYFQALHCIFGLGALIAPLIAAPFLGDYESDFLKFDKHIEFDFNNSSTIFANTTTQNSTHYFPNEGFEIISEIPRVTYAFTIIGVFALLVTTLFFIVCIITPKDSQGQRTDETSTGKKNVIFILLIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RF65</accession>
    <name>A0AAV4RF65_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rho GTPase-activating protein 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_221325_1</name>
        <name evidence="7" type="ORF">CEXT_259661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007680">
        <property type="protein sequence ID" value="GIY18845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RF65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="6">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY18845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="41132" checksum="A1BDB88A2745C700" modified="2024-11-27" version="1" fragment="single">MSDVYVQVLYDFHYRTENGEEVTMKAGEELLLLKKSNENWWQVIRDSDNNPFYAPSNYLSIIGLNCKESIESTDVNSNIQSNNSSCSVNQNNIALKSKCIIDVQKNVNKLSKSVTENLSIKKVTDALSFKNPLCENEFLNNDHDHDDSYQKQVLLTNELPSKIECENEISTSYDSSLLQDSMSPIYVNIPVSFGRLPPSPKPDQKPIRKLTNDWFEYVEEESGRKYYFHSASGKVTWKPPRRHENMQSTPLSSEPSSPKSISSLNAVPDPPPKQLKPKLKKLAHSSNESLESQSSPCMFTILPPGWSEESDSNGAVYYHHGLSKKKWYASSADENGRTYFMMRIILSLYGNYLISLFPQIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RIW0</accession>
    <name>A0AAV4RIW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_225811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007887">
        <property type="protein sequence ID" value="GIY20454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RIW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7741" checksum="4CA3A4E8A58F8ED4" modified="2024-11-27" version="1">MDSDWKIDSEHNVGQARNRLCISSLRSLLLIRFLPLIFESSKPHFPSLLSLALSHTELQPLKWKTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJB6</accession>
    <name>A0AAV4RJB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Calcium-activated potassium channel slowpoke</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">slo</name>
        <name evidence="14" type="ORF">CEXT_21461</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007910">
        <property type="protein sequence ID" value="GIY20582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060072">
        <property type="term" value="F:large conductance calcium-activated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF33">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01449">
        <property type="entry name" value="BKCHANNELA"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="13">
        <location>
            <begin position="7"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated potassium channel BK alpha subunit" evidence="12">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="161"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY20582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="340" mass="37350" checksum="BFE8A9CAB49F0A29" modified="2024-11-27" version="1" fragment="single">KIIVTEQVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDEIRVIIQLMQYHNKTHKMHILNIDSTHSFQAPDMPNWQNDYLCGTGMEMYTENLSPSFGGMTFPQAAVALFKKGVRAVQVVGRANESVHNSTFPTFTPPEIPKRVKLRVSNIAGQVGGRHNATYHGSQGTTVAHGTTARQRNSTSGLKPQRAPGANPATPLLTSPATKNGVGQPTANPGLFPRPTSRAAGTNGSNKQEGPLAVGLADDQAKDFDFEKTEMKYDSTGMFHWCPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKTCCHRWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RP69</accession>
    <name>A0AAV4RP69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_353321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008252">
        <property type="protein sequence ID" value="GIY23245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RP69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12768" checksum="F2BE02D23DEDAE1A" modified="2024-11-27" version="1">MGNRLPEILELEETHQRKYSSLISEKLALKGFDKSSSGVQSSQKLLWKVPTNSSVLFVNGKPILSAIHLESYGGYLTYGDFLSTFIQRVVEEKLQGSEYKFIFYFYCRSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RT07</accession>
    <name>A0AAV4RT07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_143001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008440">
        <property type="protein sequence ID" value="GIY24724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RT07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8934" checksum="76B2BC33AECB3320" modified="2024-11-27" version="1">MEAMCSGSRSRALKQQVKFSAWLNVRDRIHEFKYDNSTGFSSTTGRFGGKLIRRKNEKIKQKVECRDFSFMTMTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RT51</accession>
    <name>A0AAV4RT51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008421">
        <property type="protein sequence ID" value="GIY24562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RT51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10629" checksum="2077290F480CF720" modified="2024-11-27" version="1">MVMCVRTSLPRGRKGWGGGAEFSSHANAGRSLLEDVSECRDIDFRCYQRCKISAGFICIRVGTWNCSDAKDSQKKGVAQMEIFILTVFLASFQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RW34</accession>
    <name>A0AAV4RW34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_196101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008348">
        <property type="protein sequence ID" value="GIY24078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RW34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039323">
        <property type="entry name" value="ANKRD_45/46/60"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677:SF4">
        <property type="entry name" value="USHER SYNDROME TYPE-1G PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="8" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="9" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="182"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY24078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="221" mass="24217" checksum="5018B393A12EE7EA" modified="2024-11-27" version="1">MPIISIGRGAFSLLLDRTPVHWAASKGHIEILSLLLQAKCDIEVIDKFGMTPLLMAAWFGYKDAVQLLVKAGANLRAVNRQGQTVLHCAAQNNQEEIISFLLENVENLNIDAVDKNGMTTVHVSAANNCMAIVEKLIQAGAEISIKDKSDRSPVHTVAIRGHHLILVRLLRVGVEVDDQDEEGKTALHLTSEHGHQKALLTLLEHNCDLEAKDTKSRTALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYQ4</accession>
    <name>A0AAV4RYQ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_125071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008818">
        <property type="protein sequence ID" value="GIY27443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="15138" checksum="93891D5970F0F2EC" modified="2024-11-27" version="1">MVNTNRGAQSIPMFQNLFDHSWYARNLCFDDRYDCCQNLASARQKRTACWIETLCLMIVRITHDHAKPFLSNRMSFNQPSTPNLMRLHRFKKNPVLCWQRHMASSLLHREINKGKRKDRAGGGEGVQHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZT8</accession>
    <name>A0AAV4RZT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_493091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008752">
        <property type="protein sequence ID" value="GIY26965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8138" checksum="107B48DDD1C0A894" modified="2024-11-27" version="1">MSADQTVEESHLSPFLLEPIGKSYQWIPQLSHLAAIFLTAVIIDILGRLIIPSPIRKPPEETVNESHFEFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S114</accession>
    <name>A0AAV4S114_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_375701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008623">
        <property type="protein sequence ID" value="GIY26082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S114"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11535" checksum="989DAF9CF25CDC7F" modified="2024-11-27" version="1">MFHSTPYTTPSSSASLLLHPFRPYINRIVIIIAQRGLLLLPPAWRLRSKTRRYFLSTTPDEIFGGKMFDIDSVQLFTGCCGGAIHIWGGEVAIQRMGGIPKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4K6</accession>
    <name>A0AAV4S4K6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_674451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009023">
        <property type="protein sequence ID" value="GIY29083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4K6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13748" checksum="B7CB97CED515F919" modified="2024-11-27" version="1">MDSWLSTRPPRVVLRTFWGIDILWSIGTSLLGAGIARLLVGVGSFLIMTVDDRVFLFAPPVSALDHTFRPPLSTAMMDWCWILTPIILSHLEIAFSLHIRLSSNIVQRINSAPNNNYKIDSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBQ8</accession>
    <name>A0AAV4SBQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_325771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009175">
        <property type="protein sequence ID" value="GIY30101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13228" checksum="D22056AAB6E23AD9" modified="2024-11-27" version="1">MAEDDKGERGGGDRSTENLFDSSSPGEWDVTDFPILITIRIPSTRVGLVEKFLHHALLILFFSLPILLPKIVMKGCEEHVSGLSYIFSACSTNSPHPPTPQRLGGMWEEGDARCRKEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIX0</accession>
    <name>A0AAV4SIX0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_107431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009759">
        <property type="protein sequence ID" value="GIY34373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9374" checksum="904575CFC39773A0" modified="2024-11-27" version="1">MAPLLSSVYGWGFSVCRFPLSLTSLPAPESEMMNGMLLPYTGVPGAANSFRDRPSLAVVWHISLPRKGMILHRNRIDQKGELRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0E8</accession>
    <name>A0AAV4T0E8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Speckle-type POZ protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">spop-b_57</name>
        <name evidence="2" type="ORF">CEXT_528331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010403">
        <property type="protein sequence ID" value="GIY39097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0E8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="487" mass="55878" checksum="69C4580898FB3EDD" modified="2024-11-27" version="1">MGFTVQWALTNPRYVWHAVRESIHSPAFVVDALEGTKWSLGLCGKRLSDENHFEYCLFREGDCDVGVEEIEVNYELSLLRADGSVLEKGETMNRSFRKGGTCGTGVHVTPGNRTTLKRLGFTKDTLTTRCRMWRPDGKATENVHCFVRTRVEEEKRSFVWNIEKFSTLRASQKTTYTMKSFMTNEPLMKVNHSLVYKGIYPGLIQFKFTAANYVKMKFLEIRLFTLDTKGNRTEFLKRQNLFCDGEIFYVILSWFVTENQFLEAKKMYFPDDVFSLLGECTFSTGTVHQQIEAVHYGDFPLQTKLPGSKCPGAEARAETSTSVSEKNRKSSFNHGPMSDAKLKNETCSFPTHKNVVGSAVFEGRLSNDANESVCNDDDTARRMLEYMRTADVDKLNWKSACRFYTYDKKYQVLKERCRSYLKTNLLPNNACEALVLADRHCDEDLKGSVQQFILKHSKEVIDSAQWDSLMKTDIHLAAETMRLKCKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T595</accession>
    <name>A0AAV4T595_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G_PROTEIN_RECEP_F1_2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_263733_1</name>
        <name evidence="2" type="ORF">CEXT_693111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010614">
        <property type="protein sequence ID" value="GIY40451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T595"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19336" checksum="3B43EE5176789667" modified="2024-11-27" version="1">MFLLTIQRYKKHLKVLESRRCLESREEHLQRQLVKSNAVAYLIFLGFWMPFLVTIVTSSPETIIRAIKRDSSQVDYVSGPTNSVENALRIAQSFSCFCPFIYAFTNGTFAQAFVHLVKYFCCKSHSSSPKVLYKKGPEAQFVCIGMETRSRGTAVTSVVTHESSRNSSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8E5</accession>
    <name>A0AAV4T8E5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_540051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010688">
        <property type="protein sequence ID" value="GIY41030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12728" checksum="021148427B636B2B" modified="2024-11-27" version="1">MFLDQRKSGVSRHSRFTEDLTNIKSISVLHLEEITRTVSVGIEITITFDNHIEVMSAIMEGRKKEKEKRSESRRRKKQPAKKEEQLNLFESRTDASIFFNEEGRADGLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDD3</accession>
    <name>A0AAV4TDD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010904">
        <property type="protein sequence ID" value="GIY42867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14195" checksum="C453F94F42FE1FE2" modified="2024-11-27" version="1">MDDSERVKYFHPKITQIRGHKFQSGKGFSNISQSNKGKPKTLVCLFPDGLIRYKIYIKRNAINYFIGGSNKRKLLPTISRDGEVAINNSDFSREEPKEVTSSIILSGENCVGEGRRTKIYRSIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TE13</accession>
    <name>A0AAV4TE13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_253221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010915">
        <property type="protein sequence ID" value="GIY42995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TE13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10808" checksum="06149CB8CA0EDA5C" modified="2024-11-27" version="1">MADEEPKDSSTEEGEFPRKHRVARNEACPSGPVESRLADLHLTSVFLSSSFLKPKPFIAKDIHSSPSTSVLRNAIKLFKRSLASVVHQRHCFYSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGW1</accession>
    <name>A0AAV4TGW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_596411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011324">
        <property type="protein sequence ID" value="GIY45823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16966" checksum="B0635DC717D87A13" modified="2024-11-27" version="1">MPGGEKKKRNKKNNNKESRRRSTPLLLPYFGSSDIPKCLFLQEPLQVKDRFGSLMKPKPKMVPTDWGLSARRREKKGTKVLQQQRIKKKILHQPLLLPFIFSCSPIPKWFFPPRASSSKGSIWKLNEAKPKMVPTGWCLSPGGGGRRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKK4</accession>
    <name>A0AAV4TKK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_499021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011259">
        <property type="protein sequence ID" value="GIY45312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11205" checksum="C37B740504C15E8E" modified="2024-11-27" version="1">MSPSGFEPEACITKERQPSVTAISISRISLSISYLYLASAISRIDIAHMEPLDTVRIKLFLRSWDKDLPQFFLRDAKNNPTLKRLFFRFILRLASFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNS5</accession>
    <name>A0AAV4TNS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_750481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011520">
        <property type="protein sequence ID" value="GIY47066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12273" checksum="69E9C3D7E4157B7B" modified="2024-11-27" version="1">MKLSSRCCSDPRSAKVVSDHELIGGNRVDRSWIERQTRKETKLSQPQPWIKTPAEDKKGALFGSDKNLRRETPNGIRKRFRGWGGIKLSDKESFYEQWHADSGRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS67</accession>
    <name>A0AAV4TS67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">M514_20056</name>
        <name evidence="1" type="ORF">CEXT_44741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011772">
        <property type="protein sequence ID" value="GIY48904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="25515" checksum="FD702FC46D83526C" modified="2024-11-27" version="1">MHFSVETLETQHRWFSGRMLACHAGGPGSIPGRCTIFIFFQPAGRTIFISGISTLRCTLVSKPSRRSIGGSVVECSPATRAARVPFPADARFLSFFFASWPNDFYQRNFHAAMHFSVKTFERQQRWFSGKMLAYHAGFRFRFPADARFLSFFQPAGRTIFSSEISTLRSTLVSKAWRLSVGGCVIECSPATWAAQVRFPADARFLSFFSQLAERFLSAEFPRCDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U0D2</accession>
    <name>A0AAV4U0D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_270479_1</name>
        <name evidence="2" type="ORF">CEXT_603291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012084">
        <property type="protein sequence ID" value="GIY51197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U0D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33964:SF1">
        <property type="entry name" value="RE45066P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33964">
        <property type="entry name" value="RE45066P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043641006" evidence="1">
        <location>
            <begin position="20"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="23697" checksum="BB7C5535475F763D" modified="2024-11-27" version="1">MDGIKSLLVLSALVSVALADSECSVDGLKCCLSEFLPLVSPAGIRLTAQRLQAACTIGHDTLECISDFSDQCVSQDNHQLDQSINETKNFISHICQPTSNFTKSVEEYEDCFLNSSESFRICYNKTLLPESTENDDESKWKAECCEYKQLRNCAVQSVENNCGATASQVLQDEIVHLNGAGLELACKDVFEKCSNAGKMLASSLLLVASLFVLRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U207</accession>
    <name>A0AAV4U207_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_328411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012167">
        <property type="protein sequence ID" value="GIY51824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U207"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14457" checksum="379031247518CF85" modified="2024-11-27" version="1">MAQLKKREREREKRLNKYTTRLLQMRGNEAIVFCPVVEQVLSLIWKMSQGAADKDCNFRNPFPLESGWCSCGTNYVRGAVGSHIESGHWLQMVGKILPSLGERERMVAAAVVFGILSNGLFVVWVCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3A0</accession>
    <name>A0AAV4U3A0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP synthase F0 subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_676521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012219">
        <property type="protein sequence ID" value="GIY52274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3A0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="12851" checksum="551D27B0CD5BC8AF" modified="2024-11-27" version="1">MLVLGSSVIIVYFCVVTHTARNPAVAFASMSSKPCLFQMFGTAPISPYQPNLLVYPLLLSILYFIIVFLLYLFFEYHFQLWETCLVTLGLEQLKPSAWAIKKMSGSNFLVKYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5G6</accession>
    <name>A0AAV4U5G6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_77791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012318">
        <property type="protein sequence ID" value="GIY53046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5G6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="25446" checksum="BE9BB9E4D65BEA86" modified="2024-11-27" version="1">MRLGGQRAGLLMGEKKKKKKKNPNLKPCQQVRSKVTPKISRIIREFENPSIVFKKKILAVTPLWSRCCSWGCSFHNALVTVVLPSGHLWATVAPASMSSHWTRVFNYCDVAASDWLLESQKRCRIRLLRRSRSRVQCPLQEREEEQEQEGMSSEEGGGSAVHHAAQVVPRDVGDGLTLRRGGESQRVSRGMFTTLDFWSLTRSRNQAMRQSHVKGFSANEKKGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB94</accession>
    <name>A0AAV4UB94_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA topoisomerase I DNA binding eukaryotic-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_204031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012593">
        <property type="protein sequence ID" value="GIY55018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA topoisomerase I DNA binding eukaryotic-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="13522" checksum="7D9CC94A5BC2A501" modified="2024-11-27" version="1">MHSVFFQKHHRNQMRLSKKTEEVAGLYAQMMGHRCASTQRFKNNFFNDWTEVMTSREREIIEDFRYCDFADFKDYYKQKARERKTMTREEKLVSHHFQNISLNYAKYFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBM5</accession>
    <name>A0AAV4UBM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_373011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012612">
        <property type="protein sequence ID" value="GIY55157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13980" checksum="2C180CFCF9FCD76B" modified="2024-11-27" version="1">MTRHFIFSEPAIYSPSYNRPAKRVHLLIPRSLSTGRRGGQYLLLQLAIRCAIRHSHGGPVSCNCAVTNARRGVSLSLAWEGKKKKKRTTYSIPCAQFPRWAVSIKQKTPPSLIRGPARSAPMCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCC0</accession>
    <name>A0AAV4UCC0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentapeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_741511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012637">
        <property type="protein sequence ID" value="GIY55412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="23782" checksum="BEE7AF8288D48CF8" modified="2024-11-27" version="1">MKVIRFIYELMTFQINSSLLDAKVTFGWLLNAKEAFNSFDAKEAFNSFDAKEAFNSFDAKETFNSFDAKVIFNLFDAKEAFNSFDAKVIFNSFDARVIFNSFFDAKVIFNSFFDARVIFNSFDARVIFNSFDTRVIFNSFDAKETFSFFYLMQKKLSASLLDAKRNFQLLYLMQKKLLALYLITWMPKEQSRNEDNQFIMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPQ8</accession>
    <name>A0AAV4UPQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tachykinin-like peptides receptor 99D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_04365</name>
        <name evidence="3" type="ORF">CEXT_396371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013246">
        <property type="protein sequence ID" value="GIY59841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY59841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10091" checksum="864DC1D40B13B69C" modified="2024-11-27" version="1">MCVPPQRLPVGNFSGQDRDRNPSFVPLRPRMSKVAAYAILTSVWLAGGALSCPSLIYSTTMTFRYADKGQRTICYLVWPDGPAGHSYADYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UR19</accession>
    <name>A0AAV4UR19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein transport protein Sec24A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sec24a</name>
        <name evidence="3" type="ORF">CEXT_653061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013314">
        <property type="protein sequence ID" value="GIY60341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UR19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000004">
        <property type="entry name" value="SEC24 homolog B, COPII coat complex component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="2">
        <location>
            <begin position="530"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY60341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="621" mass="67641" checksum="AE984C365A9CC507" modified="2024-11-27" version="1" fragment="single">MSSTSRKILLNGKDWLKEFFQSNSRFLLRQGKIRNLDGKNDKEFLKINKKEKMSQNPNLSQPFPYQNVFSPNTNQPPSSLNPMSGSPFPPPQFSPANIGTSPALMPQPCPPFDGSPYNAQNYNTRPSLPAEHSIKPPPLQNLSGMNPSLKNLSSPFPVEKQNSFPHQNGPFPPSPFNNVNSTEQTINGSISSQVNGVGGANRSVQNVPPSSPWASQPRMPLISGGQPNQKLSGEGVGPPPINQFPSVPPQSLAVDGKTVPKLSQVPSSSGLPMPYGNQAIHSTSPQVTPGTSQPPSARSSRNPSPIATQRYDYMEGQFSNKPSPTNSSLNLPSLGASPNPGLIPPNRRNSGDARQYTSPHPPVHASETTISQQVGYSNQSASPYASPLANQPNSIQPPPSAFSNSPQPPPAPSMYNSSPMPPPNLTQSPYLQSQLQSPAPQFQGGLPEGPVGGVAGYDPQLHAKMAGLSVHSSFSRLWGNDNINLLQDRNILPPVPFEPPKPVLTPERPNCSPDIFRNINSLSVIQCNTIVRCRNCRTYINPFITFIDQRRWKCNLCFRVNDLPEEFLYDPSSRSYGDPARRPEIKNATIEFIAPSDYMLRHPQPAVYLFLLDVSHAAVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UU92</accession>
    <name>A0AAV4UU92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_590401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013457">
        <property type="protein sequence ID" value="GIY61359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UU92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8363" checksum="42CA93E86507D1E1" modified="2024-11-27" version="1">MPLSGLQIYHLDVLRFEVFSRSSILAKPFCKLSKQVTISAFGCSNLLECPYTTGATYLGKGNDYAEIKIEITLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VA11</accession>
    <name>A0AAV4VA11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_351661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014122">
        <property type="protein sequence ID" value="GIY66484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VA11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11178" checksum="78BA1578247C080F" modified="2024-11-27" version="1">MHYLQVDQKLQPPLSLLSYPNPERCRVLLLRCTRSLAHVINCSIVYCSGTWWQTKEKKQNKKQESKSKKKGAVSCPFLGGIQLPGPRRCRPAVILESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJ93</accession>
    <name>A0AAV4VJ93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_515581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014617">
        <property type="protein sequence ID" value="GIY70029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJ93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="282" mass="31715" checksum="F348BF37F29F60E0" modified="2024-11-27" version="1">MLNLTLIQKHLIGFLEYKRIIGLVSDCNVNHNRQPRYRAELSRDDVFYHRVTDSGTPYGPSIPARPIFSPKGSQYDRAVERSPLHGKDFQSLATCRDCPGHYWDEPKTACLLPALTTTLKERFYTHTQKCTPFVVLRTDLDSCTSMDYTKIYPITCAIRTHGGFQELSAANDGGLYYSSHIDFAKRPVVYVGRDTVDLAAIKFGPKDFGQIPSSVFRGQLGEIDFQTKPRPSFRKVALRSRPSPKSRVGAHPLLLVSIAVGLLPLKRSYALRLPALGWISSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMM5</accession>
    <name>A0AAV4VMM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_782741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014796">
        <property type="protein sequence ID" value="GIY71378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10617" checksum="2CC53DAA19EB9CF3" modified="2024-11-27" version="1">MLSSFPFVLWSDVIVRIPFPSPNDQLRSGILTSVLFADSILSRLSLTRYAMRVITSPLRLNYHTDISRPPVKLLAIYENVTNNPEFIIVEKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VS52</accession>
    <name>A0AAV4VS52_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">eif3g</name>
        <name evidence="9" type="ORF">CEXT_277371</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014996">
        <property type="protein sequence ID" value="GIY72838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VS52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="201"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY72838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="283" mass="31742" checksum="FB330F5E0FA49DFA" modified="2024-11-27" version="1">MPSILDSKPISWADQVEQGEADLAPPGEVVRGDTKIITEYKTEDGKKVKCVRYYKVERKMVSKSIAKRKIWKKFGLAANDPPGPNPANTNVCEEIFMQFLSNKEEEKGQEEDPLAKLKGQKMVKCRICKDDHWTTQCPYKDRFGGLPEMANQETAKPATPTAANSQAEEKVKAGKYVPPSMREGANRRGESMAPSRRDETPTIRVTNLSEDVRDSDLQELFRPFGTIARIYLAKDKSTGQSKGFAFISYHRREDASRAIQSVDGFGYDNLILSVEWAKPSGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSG9</accession>
    <name>A0AAV4VSG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_669491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015066">
        <property type="protein sequence ID" value="GIY73330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10779" checksum="9339A055C594F66C" modified="2024-11-27" version="1">MAGPGSNGGNLLIKFQEHTYENGIFCSANRSRPRFSAFLSCHSAACRRKYGLPAKHVIGKSRLLRLYFAEYCFLMEKGFPYVARYLCLSSYYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSL0</accession>
    <name>A0AAV4VSL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_552591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015019">
        <property type="protein sequence ID" value="GIY73003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="17070" checksum="542D01925B070EA2" modified="2024-11-27" version="1">MSSVRQSNTKHLVSTNFASKTSLKIIAERIGKQMLILTTRYTCPCQTSQQGVVLCVQTLILRDRTERVSELRKNEMFVRLSCPKHFCWTYWSLDDVQEEFIPADFEIDDTPFSEEDDMSASDVDDMDSLNDLLALDDLSFLDEEDEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVK5</accession>
    <name>A0AAV4VVK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_632881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015151">
        <property type="protein sequence ID" value="GIY73989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="258" mass="29059" checksum="FBA4CFA38B7DF021" modified="2024-11-27" version="1">MGHPLNLAFPQAQSNHPCTKVIEEQQQRRICTAGKPRTVYEAFDRHNSQGQPFSLDFSAPLSHIGKNTCRFSQGLKYLLVWPRLSHNPNGYCSHSSGGGASYGGGSSARATETSQRHCMENRLQRRLLHISESVGSRSPQKMTQVLLGKPRTVYEPFDRHNSRSQPCSLDFPRHCLISAKTLVALSQGLKYLLVWPRLSHNPERILLPFIRGKGTSYVGGSSAEQQKLLRGIAWKIDCRGDCYTFPSRFRARVFNFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W860</accession>
    <name>A0AAV4W860_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_531501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015826">
        <property type="protein sequence ID" value="GIY78966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W860"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10190" checksum="CCAC3BD630241BF2" modified="2024-11-27" version="1">MIGNRSPVLEFRHTIRKVKLAVRRRTPYQWGFAVRKGAPLDGRAPMGASPAGGSVCPTLVIWLASAAAVDTAVAENASTKKQSPDDRWLQGKGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8N6</accession>
    <name>A0AAV4W8N6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Golgi SNAP receptor complex member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_61701</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOSR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015772">
        <property type="protein sequence ID" value="GIY78594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048219">
        <property type="term" value="P:inter-Golgi cisterna vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY78594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18918" checksum="C3EEBE6268F37099" modified="2024-11-27" version="1">MSIETNNWEELRREARQLENEIDLKLVSFSKLGTSYGSQEYRNENDTVPLLSSTNSDHMFETMALEIEQLLSKLTDVNDKMISYCQTQAVPGSTVTHTLQRHRDILQDCTHEFQKTKANIQARKEREQLLSSVRKDIDAYKSSSGLNRRTDLYLKEHEHLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WG93</accession>
    <name>A0AAV4WG93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_381731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016058">
        <property type="protein sequence ID" value="GIY80864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WG93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9728" checksum="8022F78DB758D306" modified="2024-11-27" version="1">MRPAVPAVLCKIATSDAPAGKLNPNSETSVRAKRKIMILGRPELASSNSPLKIPFAPPNCMRAPGAFDSRTFVRHFGNSVGCRAPVLHFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZW4</accession>
    <name>A0AAV4WZW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_423371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016978">
        <property type="protein sequence ID" value="GIY87804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12061" checksum="14BFA47571F86549" modified="2024-11-27" version="1">MIYFLTTRFLSTTSGREPVTSVKSPPTSPFTQYSWPIRCLPSQSLRSSPRKSLMVNETRVVARDSIPVIATVFKLLIQGRSAKSVTRTPALQVVAKTLLCCLLFLSVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8P2</accession>
    <name>A0AAV4X8P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_88651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017365">
        <property type="protein sequence ID" value="GIY90954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8855" checksum="0C861AE3CF752B14" modified="2024-11-27" version="1">MLDDLSGSKRKLCGGVLDPLSRLSTSLKAKWDATYSKDTNLMELFNIYGELSAKCGIYILKIMCKIRPQTVTSRVLARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB23</accession>
    <name>A0AAV4XB23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_682861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017500">
        <property type="protein sequence ID" value="GIY92111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="15962" checksum="9BA1ACD0A0FA6E97" modified="2024-11-27" version="1">MIGNEKAVYLYALGVGGLAGLGAGIHGGRYAGFGTGVGVRGLGPRIRGGGFAGLGSGFIGTGYAGLGPRIRGGGYAGLGAGVYGGGYAGIGAGIHGGGSTGIGAGVHGGGSADVGTDVHGGGSAGLSAGVHGRGSADLGCWCTRWRIRRLRCWCTRWRIRRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEU1</accession>
    <name>A0AAV4XEU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_150381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017548">
        <property type="protein sequence ID" value="GIY92520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12499" checksum="8247CD2EDE1B815A" modified="2024-11-27" version="1" fragment="single">IGQLSGWSHSQMLIIAKLKLEEMPEKFMKPFLQNDKELTYEKFKGAMTSHFKETPPYATEFVKFSSAMQFENVKDFSIRVQGLSQKCLESDSENEKVSEGFKRETSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGJ0</accession>
    <name>A0AAV4XGJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_431491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000346">
        <property type="protein sequence ID" value="GIY94076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="277" mass="31626" checksum="5935B0261D26A233" modified="2024-11-27" version="1">MLENSHYKLSQGNLSVGAYTAYKFDKQSESRQLQGTGLAQCKLFLSCSPTVRDTTDQRVSKKIAVKNYHLPLNRQALSRTTPFGFESNYRFPPVRLFLSSKLPGIFEGTAASDKIFFEYFIAYGRRRVSVKVSGLDKALWLLLCGRTTSFGFKSNYRSAPSPVRLFLSSICPEFLKEQPPLIKYCSNNSMLTEDGRRNSIIFASKIHESCPSFVDRAEKKMMLYSKIPKSKLCSRFSLAKRFVPDKGQKFNQVCYEVHNEKFSPQDQIGKYFISLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHD0</accession>
    <name>A0AAV4XHD0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_73751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017682">
        <property type="protein sequence ID" value="GIY93635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001708">
        <property type="term" value="P:cell fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.820:FF:000014">
        <property type="entry name" value="Optomotor-blind protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.820">
        <property type="entry name" value="Transcription factor, T-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046360">
        <property type="entry name" value="T-box_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036960">
        <property type="entry name" value="T-box_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001699">
        <property type="entry name" value="TF_T-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11267:SF181">
        <property type="entry name" value="OPTOMOTOR-BLIND PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11267">
        <property type="entry name" value="T-BOX PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00907">
        <property type="entry name" value="T-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00937">
        <property type="entry name" value="TBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00425">
        <property type="entry name" value="TBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50252">
        <property type="entry name" value="TBOX_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="T-box" evidence="7">
        <location>
            <begin position="33"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="119"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY93635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="332" mass="37189" checksum="353CF363E730C16F" modified="2024-11-27" version="1">MVLNDTISHDTNVDIVDDKFLYRIKSAQFFLRNFQTRQISGPRASYRNRTHWAGELCPTILNSMHKYQPRFHLVRANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITRLKIDNNPFAKGFRDSGAARKDKRQNSLFGSHSYQEESLTASPPEDGRGDEADDSSDNENVDVDTPDNDDLEPQTLVNGHHQSHHSPGTNSLRMFDSSIPRGSPTSPAGSASPGSSASTAEQRMMHEKLFGGADLAGLENLQKYLPLPYPPSFYTGLMGHLPFLMPNPTAQQQIGALFPPTDGAQLAAMRQLHAQLGHNRLLMDSLQDGLVGGQDPSFCQWWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHD6</accession>
    <name>A0AAV4XHD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_646191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017651">
        <property type="protein sequence ID" value="GIY93346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13127" checksum="B88D5ECA23A9483F" modified="2024-11-27" version="1">MVRRKRFHPICIYAREIKTASEQQHLARGGIFQQQRKGWTKNLYFICSRGEEEKVSSLFTQFEGWRRGWGVLRGDKHWEDIVCSVAKWQLRAPSRNALCKAVWKARFPAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHL6</accession>
    <name>A0AAV4XHL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tyrosine-protein phosphatase non-receptor type 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PTPN23_1</name>
        <name evidence="2" type="ORF">CEXT_780611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000266">
        <property type="protein sequence ID" value="GIY93435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF30">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9316" checksum="0EC9B5FEF0A558BC" modified="2024-11-27" version="1">MEAVPRLPMISCDMKISPQNTEFGRILRKNAIKAPMDFTGCSILKRYYSQLHKLGSRFPMTDDGPACVPFMWTDIYSGLLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMH1</accession>
    <name>A0AAV4XMH1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_49431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000645">
        <property type="protein sequence ID" value="GIY96322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15786" checksum="02C85D369A78759D" modified="2024-11-27" version="1">MVKRKKESTACFLAFDLYTTPEITERPSAGGRKETTPSETYRLLSTTYGLRDSATNRCENTHLFPAIRPRKLLYRTGPLRNVGRKWLNDFSLPSEEGKKKVLLAFWPLIYIPHQKSQSVHLLEEGKKPRQVRHIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPY7</accession>
    <name>A0AAV4XPY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_635451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018019">
        <property type="protein sequence ID" value="GIY96200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10123" checksum="5BD92FDA21B757C9" modified="2024-11-27" version="1">MHEYATYNSLKKLHFILRAYKEWNSTLIVSYSACYRTHLKKKKSSKKGGEEEFSCSAGDDSAKNKSSPPQMKIGEYLARINALASQRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQL6</accession>
    <name>A0AAV4XQL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_262001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000772">
        <property type="protein sequence ID" value="GIY97346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="19525" checksum="220CF59CFC6FED6D" modified="2024-11-27" version="1">MKNDIRETIVFKSISEKAEIAFKASSLAQANQFVLFVHQNCRLIIHSVSVPQRIFLSDVSDMLNNSPAVSGDKAETAFKAISPAKRGNSYFSSIKTGDLLLIRKLRQPLKSNQSLHKHEPIRPFRPSKLETYYSFGECSAIFLLSDVSDMLNNSLAVSGDVSVSSPKSWDSDTVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XW22</accession>
    <name>A0AAV4XW22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Neurexin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NRXN1</name>
        <name evidence="3" type="ORF">CEXT_549041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018235">
        <property type="protein sequence ID" value="GIY97968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XW22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Laminin G" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13708" checksum="75228AE1799B7889" modified="2024-11-27" version="1">MGTEDHPIGELSVNVNDHQYHVIRFTRSGPNSTIQIDDHNVRTKQPTGRQHTIFNSHSKIQVGGKFNTIKNRIERPFQGVISGLVFGGNRILDMAAEDDPRVSLQGGRRTAYRHATWRADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWK8</accession>
    <name>A0AAV4XWK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018275">
        <property type="protein sequence ID" value="GIY98269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14594" checksum="067234CC231E2161" modified="2024-11-27" version="1">MYRRFHLSGMDGWNGALTTIGTPGGVDSRHLLMQDLAVLVVSLLFFARPQNVPDEEGPHSRVQHGAHQNRARVAVAKHSSTGRKTKCFEYHCLIQDFPSTKCESFTSNHSALLSSAVDDKLQSQLNSISTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1J0</accession>
    <name>A0AAV4Y1J0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_612741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001137">
        <property type="protein sequence ID" value="GIZ00230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1J0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13779" checksum="C41BEDEA12598939" modified="2024-11-27" version="1">MYCESLQGFSLYIHLDNEYPYELRSVYIDCIEESADPNPRQSYLFALSAIDIYPNESPNHPLMVCEGESGVQEMAAWEISIGHHRNPKWNRYIAHRCNDPPPPTWPDPSVRGCSDYKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y208</accession>
    <name>A0AAV4Y208_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018516">
        <property type="protein sequence ID" value="GIZ00202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y208"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="14511" checksum="1829474393B0923C" modified="2024-11-27" version="1">MSRKKSFTTVIYSLCSSQYLLCPARSLYCFDRFQKQCKWRNRRWNCWIKKLVCFVEKHLFQHSWAFRDLLKATRDVNLLAFGECLVSFVAQSCMFVDKPLRGTLSGTWAFKREKNQCQNGMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y285</accession>
    <name>A0AAV4Y285_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_87591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018635">
        <property type="protein sequence ID" value="GIZ01163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y285"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="23050" checksum="F14EEFF54ED922F5" modified="2024-11-27" version="1">MRASLVIYHAQLADIQLRCYRNTNKLLFSVYPPSLLYPDLFTRPSPPPHPSVPPLSRVWLRLRSHSQNSRKAFRHIHGKTSSFFFFVTATSRHIHIQCTSFSCNPKHRISAHNTAPDGLAFLNPSPVVSPKFKLDVNGSPSSAHQRRTRGLLMHCCDCFIRAKGAPSLAERVPFRCNFVKVNGVNFVKLAPACSPRAFKFRLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5E7</accession>
    <name>A0AAV4Y5E7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">T11_5838</name>
        <name evidence="2" type="ORF">CEXT_426451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018660">
        <property type="protein sequence ID" value="GIZ01374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5E7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="314" mass="32927" checksum="87BE03731E61C48F" modified="2024-11-27" version="1">MPLASVGSNKNEGSVSSPENKARIFLAARTLQCRPPHGAPPLLPALHGVQLPGRHGHLPHLPLRGGRRAAPHQPLLLRRLAALRAPGLPAAVDQELRHPLLRALQVPLHHALQDQALQEVGEAGDVAGGAAQGSLFHHVPRGGHNVRGVVPVRADRPHGRGDALGGAGVAVLDQADRGGHRLHGGTRLHVRAVQDVRAAVQAVARLQPHHLRAERAGEVRQPAAAGGLLCGRAHGGGAGQERGEALLARGGGVPQLQDQQLGQRGQRAGMRRAGRRGRPAPPARRGDGLHQDHPHLGDGQRPGQRRPSPGPPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y815</accession>
    <name>A0AAV4Y815_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_609311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001560">
        <property type="protein sequence ID" value="GIZ03165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y815"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10546" checksum="78CF5BBCFFAF4F49" modified="2024-11-27" version="1">MNDGGTKHHLGNIFKIAKSAYNNVQQEMNRNYGRPASRSILMSAKYQFFSQTIGTMDMLIDKHLAQILKKMSENVSLIYSNMGVINHNAGKPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAH9</accession>
    <name>A0AAV4YAH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_374091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019020">
        <property type="protein sequence ID" value="GIZ03983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10512" checksum="22DA15551B9BFC26" modified="2024-11-27" version="1">MSVVTSSNRTESMLCDVVEIRRETASLANGIVFKSLPHFSPRIIDVSLIAERRTSAKSPTVCGFQFYHVKYGISKDAREVFSKTVVYFSKNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBD4</accession>
    <name>A0AAV4YBD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_733341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001771">
        <property type="protein sequence ID" value="GIZ04633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF13">
        <property type="entry name" value="SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ04633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="31" mass="3226" checksum="7B270488128475F9" modified="2024-11-27" version="1" fragment="single">MGIAGSDVSKQAADMILLDDNFVSIVTGVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3S7</accession>
    <name>A0AAV4M3S7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_249971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001799">
        <property type="protein sequence ID" value="GIX66522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3S7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX66522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12212" checksum="D8194769F08B3273" modified="2024-11-27" version="1">MQPLPYRHSNVLVNTLLNHPINNPKTRSGNNPKSVYSVPWKSIKLSDHWINRGCCDSSGMSFAVIKVLLFGCTGLLQIFQFCCWFLIHRFKNEIEKEWLVETNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M581</accession>
    <name>A0AAV4M581_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_791361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001864">
        <property type="protein sequence ID" value="GIX67277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M581"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11855" checksum="F4770237EB2597CA" modified="2024-11-27" version="1">MGGYGGYNRGYDNQMSGYGGYNNGYGNQISGYGGYNRGYDNQMNGYRGYNRGYDNQMKEYDGYDSGYGGYEAGNRGYGYGNVNYAEQLKVDLLKVMIVDFQTWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8D6</accession>
    <name>A0AAV4M8D6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_256301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019419">
        <property type="protein sequence ID" value="GIX67631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8D6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7770" checksum="EF9B335015F1C206" modified="2024-11-27" version="1" fragment="single">LKWKEVKTSLSSPQNKESGIKWLKFAGVVREGFSMHACKTLLVMSVFDVIGNGRKIIIAALPREYIDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9C1</accession>
    <name>A0AAV4M9C1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_522261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001877">
        <property type="protein sequence ID" value="GIX67424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9C1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10847" checksum="79ECD5F64D643354" modified="2024-11-27" version="1">MYLGESFSLEECDRLNTQVNLLSFEKSHLQIEKKAMFIVQWGKDLDCCQRSATSDTFSRSSKNKPWSLSDLEISYVQIFYFGIRHLQRINVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAE5</accession>
    <name>A0AAV4MAE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_681651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001995">
        <property type="protein sequence ID" value="GIX68727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="28" mass="3161" checksum="85130CAD1E8CA1AC" modified="2024-11-27" version="1" fragment="single">MSTDRGLLPDHSQKEPHTCCYTTIIVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCC5</accession>
    <name>A0AAV4MCC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_209018_1</name>
        <name evidence="1" type="ORF">CEXT_62311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002077">
        <property type="protein sequence ID" value="GIX69726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="401" mass="46181" checksum="465415EEF42CF3CE" modified="2024-11-27" version="1">MDTLDESSNGLFLQQLKNRLSIRDHSIQLISPDNFNLQNEEKEIKSDSSEDEGYFATLPLPEPQWGSEPDYLEFSSQVTLEFFLEELRDILASELESHSYNTVGSFLEFYDDFSRQSLPLCDFYRGYNAKILPESMSCVGLGCSLMEHMKSVMGNCYPEMKSALFLASCEEMVSEIDIYTSSSPPSQSFSVKEHVLVVLKIRMEGRDGYILLDPGYHVNIPVIVMSDGLFPNTGWFLLSNTAKSKKEYNYSCVGSYIEWQVKETRCGKVNSWSNLIYVGRKFLNYINVSEKRNLVFNFRTIVKRDKKQPVAGLYCNLEGDERFTFFFHDESCERVEVKIPFDYFQGSRENNHFECAISTCAAQIGFNETLVSRMIEGVIEAYFNSEFMPFVRILNTEIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD47</accession>
    <name>A0AAV4MD47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Teneurin-m</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ten-m_6</name>
        <name evidence="2" type="ORF">CEXT_59291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002101">
        <property type="protein sequence ID" value="GIX69996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057629">
        <property type="entry name" value="Teneurin1-4_GBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23093">
        <property type="entry name" value="GBD_Tenm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Teneurin-1-4-like galactose-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11151" checksum="AF3BB51DF378D168" modified="2024-11-27" version="1">MTPQPVCAVVPRDISEFEELLPGNEDSRTLQPQESWNTFFSHPDASFVRLNFSVPHNSRLALLARKNAPPSITSYDIMEVIGDELRRYVRGTLVSIMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKL4</accession>
    <name>A0AAV4MKL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_240031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019851">
        <property type="protein sequence ID" value="GIX72499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9615" checksum="659B45CF3FF5CDE6" modified="2024-11-27" version="1">MIEAPEPKLTPIMVRYTDNLKEQIAEISNQFEDDVRIKLAGEQLKIFPANSDIHRAITKYLTDGKIEFYVITPKNQRPLKKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN20</accession>
    <name>A0AAV4MN20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_136851_1</name>
        <name evidence="1" type="ORF">CEXT_149901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019981">
        <property type="protein sequence ID" value="GIX73734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9101" checksum="4F6B04EBD81580F2" modified="2024-11-27" version="1">MGEEAGSKPRKAIFSFITPSTTVRASYSVQKRSFTKALQRHRWFDEGELLDTMEKGGRPHEPLMPPCCVREEEEVKEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRK9</accession>
    <name>A0AAV4MRK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_40041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002509">
        <property type="protein sequence ID" value="GIX74510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21460" checksum="D218824A9789616E" modified="2024-11-27" version="1">MRIHRGRITILLRVQESKGRRANIPPPHPPPPPPNFLSYHPRSERRALRVVLIFAGHYLQSVSFINRNQFTLQGPYRYISDSKTKRSPPSHLNREIHLQRERERESKHIIFVNFIPEIVLSSQLKYLQPSQIQCIAFNQATKLISHKPPSFDRDCPAGRIRAAFNLPQTLRDIESPFSGGTIPGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTV0</accession>
    <name>A0AAV4MTV0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CEXT_290671</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01020200">
        <property type="protein sequence ID" value="GIX75823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000004">
        <property type="entry name" value="Chitinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF144">
        <property type="entry name" value="CHITINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="4" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GH18" evidence="14">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="306"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX75823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="459" mass="51933" checksum="48756AE2F3C2AF97" modified="2024-11-27" version="1">MKKKGGVKSMVQKMLKQQLNSNCFLIFDKWVQKTNCSSGQASSSEDPSCSRGGRKVEESIPTWWVKSRRDTFVRSAVKWVTDFGFDGFDLDWEYPGASDQICSLSEEYFAQVSRKERENSNKSFKSCQLQNLDSGGYEVPRLAELFDWINVMTYDLRARWLTFMGQHGAPKHKLVVGVPFYGRTYTLGSKENNGLRAGIKKWMDGGLPGPYTNASGFLAYYEICPHVNSGAWTKKYDDIGKCPYAYYDDQWIGYEDEDSIGIKMDYIREQGFGGAMIWAIDMDDFNGVCGRKNALLEVMNEKLRGYAAPTPDPRQTTEGSTLSTSKWWPPRASESTTQQTWWPPASTKSTTVWWSPNTSTTPRPSSGSGSSSGSSERIVVSPYDQPGAPDCKSGPETRPHSERDKYYWCIGDRPVLMQCESGSFYDPRKGKCAWNPFFNRADNTGYGGYHHQFRTYLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWE6</accession>
    <name>A0AAV4MWE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_223901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020189">
        <property type="protein sequence ID" value="GIX75687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12504" checksum="DB3F40B40E957EA6" modified="2024-11-27" version="1">MHTRSFRGAQKVKRIRNGRGEECTPFPPRFLLFLSGGKSLLQSFFVLASRDINEIRVEVCYFFFHGGSSKLIKSPPHLVDYVKYLCEAMQMDCVLVCKEELHLVLTPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N498</accession>
    <name>A0AAV4N498_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_677671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002859">
        <property type="protein sequence ID" value="GIX78665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N498"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11174" checksum="5FA69F0EE12846B2" modified="2024-11-27" version="1">MNFIIYLEPFVYELTIYIPENGSFEDAENAFAKVRIEPLFILEETGQSSASSRLIFDLEWVFNEDAENAFAKVRIEPSFHLGRDRSLHFCDIKAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4D9</accession>
    <name>A0AAV4N4D9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1758 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_269890_1</name>
        <name evidence="1" type="ORF">CEXT_111911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002922">
        <property type="protein sequence ID" value="GIX79306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4D9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10129" checksum="2443B4097DE2CB4B" modified="2024-11-27" version="1">MGYISVREETVNHSLFGGVISEKYKHQCYRIRLADLNESFRCNFEALDQTVICGNIIPVSSGSWLEQLHNMKISLTDLGENRNQFIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N577</accession>
    <name>A0AAV4N577_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002952">
        <property type="protein sequence ID" value="GIX79576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N577"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11773" checksum="BEFF0C9D5329EA97" modified="2024-11-27" version="1">MNGRPYLGTSDNFFLLTLLLENEPHPLMVLSFLSNDAEMFMPKPLEDRSLSRAWDVPSTGSCDWSTGRYWRDDFGVPGNRENVFLILSFFRLKKNRKGQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBP2</accession>
    <name>A0AAV4NBP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450 4V2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Cyp4v2</name>
        <name evidence="12" type="ORF">CEXT_196961</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020761">
        <property type="protein sequence ID" value="GIX82254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX82254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="500" mass="57556" checksum="36CA0F581E4A3F3F" modified="2024-11-27" version="1">MKSLPISDVDLEDGDFRRAILLVRNTVLLLLGCAFLGACLLVLRYLIWRRKVSRLIPGVKKVSFFSLLGNTNHLRLSVKSRNGHSLTVCVKSVHAFLLFLDAQQIVAGFAKILPHEKLYCIWLFCHPIIVLAKAETVELILSGTKIIEKAWFYKLLQLFFGTGLVTRDNKDHTRIFKPLSLCSLDIICETVLGVYLGAQESETELEFIYATKWGMRYVVERVMNCFLWLDFIYYSTTNGKKLKKHTQTVGDFTRNLIRQEKQKYLNGDFNVLNSKRKSLMHLMLEHHLQTKDLTEDDIAEELITFMVAGHDTYGCGYLLTLYLLGLNPVIQQKVHEELDWIYGKDVERDVTVDEFKEMKYLEALRLYPPAPFLARQIVEDTTICGYQVPKGASCVISTYNLHRDEEYFPNPEIFDPDRFLPENSADRHPYAYIPFSAGPRNCIGQKISTMEQMTIVSTILRNYTVESVDPRDELLPALTIVTTASKPIKIKIRERHSRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCE3</accession>
    <name>A0AAV4NCE3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 11">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="3 11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">UCHL3</name>
        <name evidence="13" type="ORF">CEXT_801221</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 11">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3 11"/>
    <dbReference type="EMBL" id="BPLR01020784">
        <property type="protein sequence ID" value="GIX82494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000006">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="12">
        <location>
            <begin position="6"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00055560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX82494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="243" mass="27346" checksum="DF23612A93CD7067" modified="2024-11-27" version="1">MACDKKWLPLESNPDVMNKFLSNVGVPDDFTMIDVVDLDDEHLENLPKKVKAVLFLFPTGEQHEEFCQSEQETIDAEGQVVSDRVYFMKLEANNASGTVSLIHAIANADEELELGPTSTLKEFLDRTADMSSEERGQELEMDENLCCVHEELAKEGQTEAPEADEEIKLHFITFVTVDEQLYELDARKNYPINHGSTSVDTLMKDSVSVCKKFMERDPENVNFSIMALVAGASAETEEEEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEG8</accession>
    <name>A0AAV4NEG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Neuroligin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nlg-1</name>
        <name evidence="3" type="ORF">CEXT_225331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020714">
        <property type="protein sequence ID" value="GIX81792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX81792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15531" checksum="8AE7563B1150A386" modified="2024-11-27" version="1">MGIEEDRRDRLLRTLVRNLYNYHLQEIFLTVVNEYTDWSKPDQHPINILDATADAMGDALVVAPLIRTGNYHSKLHKSSQKGTFMYVFMYKLKKAIMLNAWAVSMVKMFRIFLGHHSSIRFHIFHRNFFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJH7</accession>
    <name>A0AAV4NJH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_361381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020973">
        <property type="protein sequence ID" value="GIX84499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15373" checksum="C4784DD734E29D7E" modified="2024-11-27" version="1" fragment="single">VEDIKNPGAAQSTTGSPQRVPLEAELTKQKRTIIIPLLLTEDAKTADSENASTFNSFIKTRPPVEDIKKIPEQRNQLWVAPKGSALAAELTKQKRTIIIPLLTEDAKTADSENRFAPHPSSPGLCIVLPEEWRQLYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKQ8</accession>
    <name>A0AAV4NKQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_431751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020963">
        <property type="protein sequence ID" value="GIX84408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12626" checksum="753D282F129A7AFB" modified="2024-11-27" version="1">MHNAEVRTTFCIRLCKDRDVVNYLCRVKVADLWSAEVFRRGRGVPEQQRRGGIKFVFAGLRTLAGISQENVKASFDCRKIYGKLRSTCTGSCKTCAKCSKSRVSINRLIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNR3</accession>
    <name>A0AAV4NNR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_804091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021139">
        <property type="protein sequence ID" value="GIX86416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15082" checksum="ED04E50D9132BD2C" modified="2024-11-27" version="1">MNLFTGLNCYFFHNFREAISGCTKSLCQGTESIEKMYQIYKHVLMLADAVENEFGHLFFLVTADGCLQAFTGISYFMGLETGWITPPHSHVFILYSLTYILNWTFFIVVAGEVHEQDAVFKKPIAFKSVKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYB3</accession>
    <name>A0AAV4NYB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_346681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021460">
        <property type="protein sequence ID" value="GIX89890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12039" checksum="46AD42D6A3D6E790" modified="2024-11-27" version="1">MLKPHLTTADITVNSNQYLSELEGPPQMHDPSIAPTKCKQTKNLFPFGILSRSIPLLVYKKNFSSVPDSIYLMMSAHGHEDPGPDKYGIGFRPAIRAHYCTRVSLGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZW1</accession>
    <name>A0AAV4NZW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_494821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021491">
        <property type="protein sequence ID" value="GIX90286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="22935" checksum="3CF853166E5E79B9" modified="2024-11-27" version="1">MGNPAIRRTPSFRSHQLSAEVGERRSRCHFPTSNPVVAINAQPGALHVVLHESVKYWTTVSNIEKKPKSLAILFTFTASDIQKRKPSFTQTYNSWKTCDPSSISFRSHQLSVANVDHVATFQLPILSLPINALPPRLKHSPGLCTQPCTECVILTAGIKSACLIMDQWCVGMACMIYKRPTLCVTSQWLGILGNSVAVRVAGCVFGGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P713</accession>
    <name>A0AAV4P713_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat-containing protein 74A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Lrrc74a</name>
        <name evidence="2" type="ORF">CEXT_618541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004030">
        <property type="protein sequence ID" value="GIX91496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P713"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16479" checksum="1AE86781659E341B" modified="2024-11-27" version="1">MRVNLKFVQTLAKYEKAGRDVKVIYGSEIRYDVLPRSSQPVAESTEGEVLTESSAMVFIQRLADEKGLSLKHIFRDIHAKFINQKAEEALQNAEEGQKKGRKRTSRPHDHGRIRQSSACQQSRCPKSKSSRSCERVQCRGPGEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPP4</accession>
    <name>A0AAV4PPP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_179911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005002">
        <property type="protein sequence ID" value="GIX99054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="17731" checksum="96EE14E06288EE8F" modified="2024-11-27" version="1">MLLCCLNVIAIPHSKQLGSSVFYFDSPSANRRRSVNTGEIQDKLENPSEPFTANLVPDYGNPKKASFGNLAKRNFPIPVKIKGFGGIFGAQSIHFGLRDLEGFAKSLENPSVHFIENLVPYYGNPKELLLATSPKEFSDSCKNKRIWRHFGGSMDPFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSP2</accession>
    <name>A0AAV4PSP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_261451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005011">
        <property type="protein sequence ID" value="GIX99168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9756" checksum="D75CA90A04399B36" modified="2024-11-27" version="1">MVIILRMVGMELNELQKSSSLHEDNESIYSRLCEPILLISNKFLYLGYVEDLATLEAIQEILDAIMFKTSLASKCFETSSNTTSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXR9</accession>
    <name>A0AAV4PXR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_532131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005357">
        <property type="protein sequence ID" value="GIY01696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15113" checksum="8D2A635274DAE855" modified="2024-11-27" version="1">MDLVESKIACHLHKVRLLGSCPIKTCIIHYPPSTSHKNFKPNSHPKQNPLKRATAEDSDFQLPTTRNTVKAPTFFSPNAISTSNKFMNLDNLTEPDPPLPQTPKSRPSWSSSKNTPAEETEQELSDLNFKNSKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q120</accession>
    <name>A0AAV4Q120_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sleeping Beauty transposase HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_423861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005530">
        <property type="protein sequence ID" value="GIY03019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q120"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057667">
        <property type="entry name" value="HTH_SB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25787">
        <property type="entry name" value="HTH_SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sleeping Beauty transposase HTH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11954" checksum="0A8E6F529EC595F1" modified="2024-11-27" version="1">MPRSSELSDFEKDIIGYHKCGRSLRDISSELKYPKSTVAYVIKKWKATAVEYELPSSGSKKRNRKKKLKEEANKHIHTIVDTINVEVEPEEKINEQDVGQYSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6M4</accession>
    <name>A0AAV4Q6M4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_178551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005534">
        <property type="protein sequence ID" value="GIY03048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019170">
        <property type="entry name" value="Meckelin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21274">
        <property type="entry name" value="MECKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21274:SF0">
        <property type="entry name" value="MECKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09773">
        <property type="entry name" value="Meckelin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="371" mass="42859" checksum="640B9B3FA76CEC65" modified="2024-11-27" version="1">MLVQNSEEFQKKYLIECPKKRLWLYYINEEGEWHTEKDLYMDNVPNVFTPSISLETSKIQLIAMKYSLNGTFLGLTKINSNDLHLCQESDIEEDIAFIIGTRVERVCIRSLQYLWQSSELVFFDLYLINNQNKTELYPIPVLIRNIVVNGELVNMEKDMSKWRLVRRFFLTDHISGIEEETNLNHKHNQPVAKVFRYASEVSLKIVFKSEGKPGTIYPPLLVISYAEATPDDYMKNKKLHIFAFAWSVLQTYSWFRRSGKHAADLVTVGKFIIFMSGNLGKDVMYTLLPTSQQEDFLSVYIGIAFALKALQLIHLLVVQCNIDIFYIDWERPRVRTSSVSARTATTSKNIAETPAGADHKKSSTNFLKSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QM37</accession>
    <name>A0AAV4QM37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006332">
        <property type="protein sequence ID" value="GIY09125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QM37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="202" mass="22366" checksum="14299C41B339B372" modified="2024-11-27" version="1">MVVSRFAPMSSPAHAQQRGLSSLPIHCTEMQCRQGEAFSSPSVLENYKSGLVTGINMGITPANRKPDHVLSKAAIGRSSFKAKYHNFDYNVLLRQSIQISRLKCSFNARSTIIFRLQCSFKRKCFSASPISDGTSSCQSIPLSSGTTQTKRRANEVRSKNNGCDKPKTGYSRYTASINRLSPLIWSSSRFLLVDSFVEVSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPP2</accession>
    <name>A0AAV4QPP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_131581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006619">
        <property type="protein sequence ID" value="GIY11197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="13819" checksum="B10FD325BE4FCAD2" modified="2024-11-27" version="1">MMAQTYKNGLSGSDTSYRKSLHSRVHSTGCHQHSEGLVGQLHLTFVARETVRVIGLLIVHDALVVRNGVLAAETPHPEVPHVATLAVHKVSVWYEAARSDGLLTINAPEAVDVKGLVLQEVEYQNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPT4</accession>
    <name>A0AAV4QPT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_44601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006398">
        <property type="protein sequence ID" value="GIY09543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17410" checksum="F7BBBB9C85616E33" modified="2024-11-27" version="1">MISCYSSYRGFISRFKPPSGASHLAGAPPFGQHHSAPEDLDRPVEPRWVLCSRWDAAETTLQRLSPGCAISVLFPEDKSLANSNNPNVGMDFYPLVAPICAAIRQLLCTPAVEFQPLVTAGPSPAGSASSLLQQIGSGVQSLSENNDLDDGWKTKRERKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRR5</accession>
    <name>A0AAV4QRR5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Jafrac1</name>
        <name evidence="12" type="ORF">CEXT_208721</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01006663">
        <property type="protein sequence ID" value="GIY11581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF163">
        <property type="entry name" value="AT16346P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="28"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="9">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY11581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="24553" checksum="E2EC90E587142568" modified="2024-11-27" version="1" fragment="single">SDIALYNTHFSLLSIKYSTSTLIFEMAPELTKPAPNFEGTAVVNGAFKNIKLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSERAEEFRNINCEVVACSTDSHFSHLAWINTPRKEGGLGKMNIPLLADKNCDISKAYGVYKDDAGISFRGLFIIDEKGNLRQITINDLPVGRSVDETLRLVQAFQFTDKNGEVCPAGWKPGDATMKPDPEGSKAYFTKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QU07</accession>
    <name>A0AAV4QU07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_57921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006955">
        <property type="protein sequence ID" value="GIY13538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QU07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9301" checksum="257A0877F20486DF" modified="2024-11-27" version="1">MIFILYMGKSVDRFSTPFFRRGGHIQRFCPRHLYWLEKQVIFRYPMAAVTRGQGSYGGGERLAGDPLSGEGEGGLQDLSDGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QX24</accession>
    <name>A0AAV4QX24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_329011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006859">
        <property type="protein sequence ID" value="GIY12861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QX24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9704" checksum="A252BCC879544E04" modified="2024-11-27" version="1">MAAVGFEPTPPQRLVPKTKDHSATLPTSRIKKKTEKFFHFGHSSNPQRLVPKTSALDHSATLPTSCSSRIKRKPKFFHFKFRTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYI6</accession>
    <name>A0AAV4QYI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MFS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_271286_1</name>
        <name evidence="3" type="ORF">CEXT_412371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006902">
        <property type="protein sequence ID" value="GIY13187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008028">
        <property type="term" value="F:monocarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF303">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY13187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="367" mass="40879" checksum="04C69FB30859A182" modified="2024-11-27" version="1">MNTDGPDSFYSWTVAVACCSVYLLMYGMTRISGLLFIGTMDLHHVNREQASFPFVFGVTMRYVSGPLSGLLARRLGIRFVIVLGCCMAFVGVGSCFLAQNILQMILLWGVLYGMGCGLATCILPQIVNLYFKKHVTKAYGLTYAGSSLSGFILPPIAEILLEKYGISGTFLILAGIVLHGFAAAILLKKPKFEISSDASDKRRVFNIQSDNYNTEGNASGKLSVDQKSHHGLPTQVNRNDCFKKDKYMLSTDQSKYDSNSDIKLKMSHSSKNNTKSEKDEPKVQESTLQNPITTLSTTITYGSTLNAKQNNVENLKLNPIRLLNIRSLPDDISEYMDKEHCRHNKTSEFLSQNTKQTILIQNIYKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBU9</accession>
    <name>A0AAV4RBU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_574991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007738">
        <property type="protein sequence ID" value="GIY19309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13059" checksum="E692D1D4832501CF" modified="2024-11-27" version="1">MKRRPPKEPKPKKPKSPKPPKSPKPKKPKKSKRQKMLTLLIHCLLMCKIMLFYSRKPADSAAEANGVVNDETKENIEVDKETKEKKTKSKSPKTPKDGTPKEPKKSTPKKNFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKS5</accession>
    <name>A0AAV4RKS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_601221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008040">
        <property type="protein sequence ID" value="GIY21629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9357" checksum="74054426B4E9F3DE" modified="2024-11-27" version="1">MSNKGNFPIECPGEKKVEWDKWEGCNRIGIYCFPLQLPFNYCHVTQLEERSLASIMSPGLLFDQSCQDTVTGMRFMGGSIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RN77</accession>
    <name>A0AAV4RN77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_118531_1</name>
        <name evidence="2" type="ORF">CEXT_250251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008023">
        <property type="protein sequence ID" value="GIY21468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RN77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="347" mass="37706" checksum="D724553C4E3CD871" modified="2024-11-27" version="1">MSLQQREICKVGESPSARRRSISPRRGSGQSANEENPDQPGIEHSSDTSKSFKLTSSPSSSGCTTPEVRSPSKSERRISTRLLMQKGRKVDSPGKNKSPKHAAWKSSKFFSRSMASGELLKGFKKLSTATPVTSIVVSEEDGTSTTITTETKEVDTKTFKSRFSSLRRKSGSDSDSVPNVDSESLKSSDFTNPSLEVPLTQSSTQLTPHPRSFRSSRSASLDPTTLPNIERVVSRLPNKPAIRSSVYQPTRQGSKKTTDDICIKKTGAFLEVVPEVKRRLSGPLIEVKDKIVEENEDVEGDGAETPVQWDDSNFVDPNLLGGAIEAFLKGMGSSPSPTPTTEKEGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRX2</accession>
    <name>A0AAV4RRX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_573781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008182">
        <property type="protein sequence ID" value="GIY22683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7944" checksum="810BACCACA5E71DC" modified="2024-11-27" version="1">MPQDAECALVYLDMSKFSNIPPTATTFPQLHSRNKTSEEILLKAICPPFPVVVCSEMSNLNKHLSIPNATRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RT55</accession>
    <name>A0AAV4RT55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_654431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008431">
        <property type="protein sequence ID" value="GIY24610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RT55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10203" checksum="82DEE84816FC499A" modified="2024-11-27" version="1">MIDGLLVGSFCLFYVRRMRRHSGHQATEGVLKGKVLPSQDSTLKGDTVISEATKYAHLFYFLRIKLGICVPSGCSLEDINEAAKYVGKKQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWA4</accession>
    <name>A0AAV4RWA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008569">
        <property type="protein sequence ID" value="GIY25720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13279" checksum="A82655118A60810C" modified="2024-11-27" version="1">MVSDFRFLFHSVKTCKLPIETFSKDIESLGSIITTFIENYDILKKELILFSKEVVDFVKCTVHFDPETSDEFFEMYNDIVIYGCDVVQYFVDCKESFDEYFNVRHKLGASLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S044</accession>
    <name>A0AAV4S044_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_187001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008666">
        <property type="protein sequence ID" value="GIY26304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S044"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14384" checksum="6DB5103874D7B948" modified="2024-11-27" version="1">MIYANTMSCCVVYIKTHFPFTECEDCVNRWQYDRCPENFHPVPLHHHFRPGGKTLFGKLFRNNQLLHRFISCEPGNKCKIRTIQSLSVAREEKNILLERSLGGKKAKNWQSSEASLQKNRENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3N9</accession>
    <name>A0AAV4S3N9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_719391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008780">
        <property type="protein sequence ID" value="GIY27140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3N9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="17308" checksum="20BCB2A25BA8ED02" modified="2024-11-27" version="1">MCHNRHSLFLKAVTAAHPSSSVYSASNPAYSASNPACTLPRIQRALCLESSVHSASNPACTLPRIQCLESSVYSASNPACTLPRIQRVLCLESSVYSASNPACTLPRIQLHSASNLACTLPQRALCPNLALCLESSVHSASESSVHLPPESSVHSASNPGTLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S5K4</accession>
    <name>A0AAV4S5K4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_409481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008938">
        <property type="protein sequence ID" value="GIY28356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S5K4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9777" checksum="1B60D6FF760F31CB" modified="2024-11-27" version="1">METLYFRSALSSSHCWRHEEQLACRHVIYFHFPPHSLLLLLTPHEELVAPLVPPLLRLLLISPHKSTHSRSLWGFFSFSLGIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDG5</accession>
    <name>A0AAV4SDG5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MIB/HERC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Mib2</name>
        <name evidence="2" type="ORF">CEXT_691571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009496">
        <property type="protein sequence ID" value="GIY32353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010606">
        <property type="entry name" value="Mib_Herc2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037252">
        <property type="entry name" value="Mib_Herc2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24202">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MIB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24202:SF4">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06701">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159034">
        <property type="entry name" value="Mib/herc2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51416">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIB/HERC2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10613" checksum="DF9083DBD23FB1D9" modified="2024-11-27" version="1">MLPIGGDGKTGKVLDIRGWDNESERSVANVTWSSGATNVYRLGHKGKVDLKYIQDAVGGYYYRDHLPILGQVEATCSKAPPGKTIQDLLLEIKFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFV7</accession>
    <name>A0AAV4SFV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Monocarboxylate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_68241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009472">
        <property type="protein sequence ID" value="GIY32204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008028">
        <property type="term" value="F:monocarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF303">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17201" checksum="CC06F5806E014C3C" modified="2024-11-27" version="1">MDICDSSYRNKVVKTRPCIRVRMEGPDGGWAWAVAFAACIISFIMAGLGRMSGILYVSFIETFAVDRKSASTPFSVRSSTRNLLGPVVGILGQKYGVRAVTITGGVLATVSASVCFFAPDIVWITVLWGGLNGIGTALTVTLPQVVIGQYFDKYATLHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T133</accession>
    <name>A0AAV4T133_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_11098</name>
        <name evidence="4" type="ORF">CEXT_314611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010508">
        <property type="protein sequence ID" value="GIY39769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T133"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042333">
        <property type="entry name" value="LRAD2/Mig-13-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24652">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24652:SF67">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY39769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="324" mass="36073" checksum="2819EE6AA4DBF552" modified="2024-11-27" version="1">MVDVDVECNDDVNVECIADDMTTICKRLPNFKIRMHHSNAGSTGILKATDYLSEEEESECVAKITPPRGYGVIYYFEGMELRKDANNDCRDYIKIYNETSWSNNTAPICRDCCRFSKSEQLCQGHCGYESDGLVCEEFCDKNNGSFISTGTARSLSIHYHTRCGTCTDKKEHVGFRMVFTAFKLHSGPDVRCALSSEFQCDNGRCIWSGLTCDGHNNCGDNSDENKTGHSHCAEFPDPVKAVIVASAVIVTVLLGVLLAYIPKLSMLSFLGQKKKSATLRLSGSYRKKSSTVELIARKPSHNRTVSFQTPLPKIREMTFGESEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1I9</accession>
    <name>A0AAV4T1I9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_346101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010430">
        <property type="protein sequence ID" value="GIY39226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9763" checksum="DA686107CA28FF8A" modified="2024-11-27" version="1">MFNNATANAPLQNNQPPKAPIQAQAAAVDATVNMRPNGARMISRITRHPVLNISFQPYSDASLENANIPRCVFPVSFPEVISACNRKACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TA72</accession>
    <name>A0AAV4TA72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_345921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010982">
        <property type="protein sequence ID" value="GIY43483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TA72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12789" checksum="B74BDA418D91A49D" modified="2024-11-27" version="1">MTLHGMACGEGGSNWNLLVQQSKRSNPEPLFQSESKMSFLRQGSMSIYWWPCASYPCPSATLHNPTDFRPNALVIFRAQQRPLSSGKVLVASLNPPHSPSVYKGMGLLKHRWTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCV9</accession>
    <name>A0AAV4TCV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_637121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010947">
        <property type="protein sequence ID" value="GIY43222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10982" checksum="E714A91E0BE92969" modified="2024-11-27" version="1">MFEMLRRVPFRKDEQPTFFEKDDVLSENGFVGTRSPVNRAKHHGPSGQQHGIPPLASGRAAFGGVRRSESSASATNSRFKFHSTDESSYGKKCVVHTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVB2</accession>
    <name>A0AAV4TVB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_592551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011959">
        <property type="protein sequence ID" value="GIY50288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9109" checksum="5EE44561F6E8880D" modified="2024-11-27" version="1">MSNSCEVKSRLVYGRHLTGIDESFDSQDGGNYLIVKKRNPLMAKETNYLIAKIEELFDGQDEKSLDGQGDELLDSQDRGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYT2</accession>
    <name>A0AAV4TYT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_4591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012035">
        <property type="protein sequence ID" value="GIY50846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8116" checksum="30D8F452C14A99C1" modified="2024-11-27" version="1">MASAPVLVEPVHVPKDTVTEHDAFERGLGCHVYSALGFKVRQLGLKPTKPCPAHKASSLNAEDEHIESADNKVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZZ8</accession>
    <name>A0AAV4TZZ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Semaphorin-1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SEMA-1A</name>
        <name evidence="14" type="ORF">CEXT_762521</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the semaphorin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012065">
        <property type="protein sequence ID" value="GIY51082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1680.10:FF:000016">
        <property type="entry name" value="Putative Semaphorin-6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1680.10">
        <property type="entry name" value="ligand-binding face of the semaphorins, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002165">
        <property type="entry name" value="Plexin_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01437">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103575">
        <property type="entry name" value="Plexin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0221">Differentiation</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="43"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="155"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY51082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="22800" checksum="0D50720BB9D8947D" modified="2024-11-27" version="1" fragment="single">ECVALQDPYCAWDKSRGVCTSSRQRLWKRDNFVQNIEEGFDSRCREGGRSSNGGTTPQRSPHHSASRHDSTGNGSPPASSTTETEDELSEGGTAGASRGHQYMYTAETLAIAVTTSIVSSLVVGFISGYIFSRRCRSEEVDSPYDDSHYLEQRGSCDTPHLNHTEGFLSPTSNKPINLVLNVPPKNGNGKSANSSADNRPVQKVKKIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U024</accession>
    <name>A0AAV4U024_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_799851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012070">
        <property type="protein sequence ID" value="GIY51110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U024"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8067" checksum="4DB006CE4B724B80" modified="2024-11-27" version="1">MQGHVEALGGASTTLGPRRSRSVVDICSCNKQKKHRAPAPNMIFEGQPLWETSRWVADGFSPTLDDDDKLKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1V5</accession>
    <name>A0AAV4U1V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012146">
        <property type="protein sequence ID" value="GIY51699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19178" checksum="9E2B1DAAB2F9D759" modified="2024-11-27" version="1">MGFQNFEKDSDENFELDDIRTLPKNIFRRPFIKTDMTGRKILSPEISTFHTSFFSPRRFFFLNHHPRHRGLFVRITATERSFRGVPPPSRYRLISVQNSDATKRSELNGTERSSHERTCITFCKANTHGCSAKQEMRNVFPSRDISFCGCQPPFSFCSECLQGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U364</accession>
    <name>A0AAV4U364_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thrombospondin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_01580</name>
        <name evidence="2" type="ORF">CEXT_596361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012204">
        <property type="protein sequence ID" value="GIY52160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U364"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043416642" evidence="1">
        <location>
            <begin position="25"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17981" checksum="95544B4FF6A79DE7" modified="2024-11-27" version="1" fragment="single">MVISTRGCNLVLFFIVLVVHRVASRGSLVQDSRTTTELGNALCNKNASIAILFREMSSRPRPFTHTIVTIDFLVTNYRLTFGIDPSKGKMLLTVNGPQNLERKYQIPGNLSAGEHIAVFVPDPRESSPANLRVYVNCSLQQSIELPKSMFDMLKQNTEVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4A0</accession>
    <name>A0AAV4U4A0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EH domain-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_18104</name>
        <name evidence="2" type="ORF">CEXT_452961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012256">
        <property type="protein sequence ID" value="GIY52560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4A0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022735">
        <property type="entry name" value="bMERB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050540">
        <property type="entry name" value="F-actin_Monoox_Mical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23167">
        <property type="entry name" value="CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23167:SF46">
        <property type="entry name" value="EPS15 HOMOLOGY DOMAIN CONTAINING PROTEIN-BINDING PROTEIN 1, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12130">
        <property type="entry name" value="bMERB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01203">
        <property type="entry name" value="DUF3585"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51848">
        <property type="entry name" value="BMERB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BMERB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16339" checksum="4FD9976753CBDD9C" modified="2024-11-27" version="1">MYDLATVDSIPIRQPLTSSVHHLHRIMTSLFSCHRSLAACFAVVSQPSAKRFRALSPPSFLCNALPFEAELLSQTNCTGEKECDLEKRYEFLNEELRALLVLEEWQKTEADKAREKLLLEELVIIVNKRDELVRELHTQEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9V7</accession>
    <name>A0AAV4U9V7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RclHR1_00930026</name>
        <name evidence="1" type="ORF">CEXT_675301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012519">
        <property type="protein sequence ID" value="GIY54511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9V7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34410">
        <property type="entry name" value="INTRON-ENCODED HOMING ENDONUCLEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34410:SF2">
        <property type="entry name" value="RRNA INTRON-ENCODED HOMING ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="262" mass="28097" checksum="75648B40CA8DE361" modified="2024-11-27" version="1">MQQSSDLRERALLLDQNQSGLSQGPSSVVTLYNFGLIARARPGDVSFKCLPYQLSMVGYAPTMVVTGDGESGIHWRASLVPAAAVIPAPIAYIKVVAVKKLVVGSQLEPGGPPTGGHCLCSALSPVSPDDLHRLSRVTGKFTLKKLECSKQARRLNNGAWNNGIGPRFYFVGFRNTRRTTAKAFAKNVSINQERKLEVRRRSDTALVLTINDASQRSGCVPQMTRRAASGKPKLVGSGGSMVAKLKLKGIDGRAPPEMEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UE51</accession>
    <name>A0AAV4UE51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BRICHOS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_105947_1</name>
        <name evidence="2" type="ORF">CEXT_554871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012717">
        <property type="protein sequence ID" value="GIY56031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UE51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="362" mass="42150" checksum="7446F1A72A941490" modified="2024-11-27" version="1">MCITLKAVAYISDSQTKTFVVRYKVGEQTIPVTVVLDYKKQTEYVINMSPRATTKTVTLYDFKQKTIAYKDLTNRECFLGHLTHETLNEETDALSRIQNPVEHQPKILSLDPHRSSLTPTEIRNMAGQKTAVFCRKNEHVACIQKREAEEIDERTYHRHGYHTIRYSHYGHETRRRFRNPYRNTTRHLSQRRGNASEINNSKIENSVTSLPFEDNPFPSQSLTVQQQFPRPEHLRANFNGNSLSTHPNSNYQTPPEADVKAAPPPVPSYYRPSLETNLNHENYSSTFPPNYLSRQNEYDSSTFPPNYLSRQNGYDSQIPFDSRFRAIQENQDNRIQDNTHIKKKHPIILQETIFPNLMTLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFJ7</accession>
    <name>A0AAV4UFJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_260511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012776">
        <property type="protein sequence ID" value="GIY56526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11086" checksum="76C2A38A7206A72D" modified="2024-11-27" version="1">MKTKCACSKNNKRLRNVKIRKQVKAKEEHKFTPTVLFSNGPFRLKYSFLTPPLQLRVTFQLYNSIKSSYCSSAGVLIRVPFISMAVLTYSGLLGWPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNP5</accession>
    <name>A0AAV4UNP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_633731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013201">
        <property type="protein sequence ID" value="GIY59394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13707" checksum="30AA95BBCC1D2D7B" modified="2024-11-27" version="1">MITLHTSWIRIPCFGDHCLRDLRTLKFENHCVPPNPLAEFDLIQVNKFCSINSVRNCCSIKQLASKLVQDVIGGVGICCPVFGCRRTEHYSSSEYFPCIYCDSTCQTSTQYPFSRERICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V310</accession>
    <name>A0AAV4V310_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013828">
        <property type="protein sequence ID" value="GIY64084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V310"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11036" checksum="32690169CB529053" modified="2024-11-27" version="1">MEVCQRGKSNTSKNQQICCHQTETLRTPELSQVVSNAEGASGDTRHCVLDALREVNDSRNHFRHHHHSLEHPTTLPPPKDFFRSLLPISNVNLQEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAZ6</accession>
    <name>A0AAV4VAZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_789201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014242">
        <property type="protein sequence ID" value="GIY67462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13755" checksum="364989B37FCEBC40" modified="2024-11-27" version="1">MPLGITACVAYDGDLLWRLSGYEYGTDFSQEVGLVHGLEVSHTEVFSLSFSYGLICHEFSSELEKPFLVRNARKCPEYKSCSQVSQLQTTFISTDRALSRNSSPPKKVVNINLQQAIFPQATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEN0</accession>
    <name>A0AAV4VEN0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_781991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014375">
        <property type="protein sequence ID" value="GIY68420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13091" checksum="749BDC2B425C8E48" modified="2024-11-27" version="1">MVLFFAVGLGFWIRQNSSLVTVVGSSRGIGKFKMYSRYDLVLGWFIFSNLSDLVWIFGFVRIPRWFVGSSDMVLFFAEGLGFSIRQNSLVPLVGSSRGIVKLSDLFEIWFCSWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPJ0</accession>
    <name>A0AAV4VPJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_138351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014867">
        <property type="protein sequence ID" value="GIY71840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19366" checksum="D8455583FA906B8F" modified="2024-11-27" version="1">MKRIRIAIFNSFKQFLKNEHISLNHVLDIDYPPDPRSVLILRLLKSQGASRNPHRKTRKILQHHPHHKSYRGVSGRISIQAASPRTWGTESETENASFLSSLWQQFVRPHKERGSTMGVSNIENQMDYCVACQRGLQDSEGAFFFFFFPRALAAPFPGKRKKRTMNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPP2</accession>
    <name>A0AAV4VPP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_787511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014868">
        <property type="protein sequence ID" value="GIY71919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8187" checksum="61B72D0F1B80F203" modified="2024-11-27" version="1">MDWMRRNGQKRKAVLLKMSCRPIANKYREGKLQRTLKREIKSDTAQRQTGGPSKSCGGRIQSGGGDVRQERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VV15</accession>
    <name>A0AAV4VV15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Retrovirus-related Pol polyprotein from transposon 17.6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pol_1413</name>
        <name evidence="1" type="ORF">CEXT_270761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015132">
        <property type="protein sequence ID" value="GIY73843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VV15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15660" checksum="6B221581E3D0DB2D" modified="2024-11-27" version="1">MIDNPSSLSEAVEFTLSVEKSIQIVFPNVNAIAGKESNMTEATSEGFAKSLRCRCNITFDYQLRYPDLLVKKSDWSFRVVADPRKLNGKTIPNNFPLPNLNEIIDVKILILDNITRDFTSGPHQMLMNLNHAYLTGITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W148</accession>
    <name>A0AAV4W148_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_130181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015418">
        <property type="protein sequence ID" value="GIY75924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W148"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9995" checksum="F5B0BC3311CBF045" modified="2024-11-27" version="1">MDICSNDHVRIGVNWGKCDDFFFMRYLPIFWPEGCQYLRKQDYRPLSRIWMSASAGVGTRQYIKRCAEDTGIGMHSGMSDPSAMYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5K1</accession>
    <name>A0AAV4W5K1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_393441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015635">
        <property type="protein sequence ID" value="GIY77484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5K1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="21000" checksum="D8EA5598B965400C" modified="2024-11-27" version="1">MQIHFHINCQKVTSNYSITIKYSAKKIKRLSIKQQKRFKDYPSSIKRDSKTIHQISKEIRRLSFKYQNRFKDYPSNIKTDSKTIHQISKEIQRLSIRYQKRFKDYPSDIKRDSKIILQISKRDSKTIHQKSKEIQRLSIKYPKRFKDYPSNIQRDSKTIYQITKEIHRLYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8P0</accession>
    <name>A0AAV4W8P0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein SSUH2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SSUH2_0</name>
        <name evidence="1" type="ORF">CEXT_61711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015772">
        <property type="protein sequence ID" value="GIY78598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8P0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052789">
        <property type="entry name" value="SSUH2_homolog"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48465">
        <property type="entry name" value="PROTEIN SSUH2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48465:SF1">
        <property type="entry name" value="PROTEIN SSUH2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="30255" checksum="D9F78C008F665F76" modified="2024-11-27" version="1">MLVMYTLESFTEMRQVSWSFEPYTGVPLDEVNVSEPPPEPWDIECPLPKPFQMHSMILDVPHTDVLMICHVCGGIGSRRCTACSAAGWERCSLCLGDGHKISIQGYRERCFRCLGTGRKKCWKCNGETIAVCRGCGGTGQIRCFIAITVSWSNHVDTDILEPSEALAVTEKLEYANGHLIFQDEKSVIPSVSFPVKDLQMIASAILEKHRNISFSEKLLLQRHGVWAIPVSKVTYEWKEDEDVFFIYGTKNEVFAPEFPESLCCCCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9N5</accession>
    <name>A0AAV4W9N5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_327141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015818">
        <property type="protein sequence ID" value="GIY78924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14035" checksum="30C66A5381F335D5" modified="2024-11-27" version="1">MPTYVSYTMPSNTCHVKLNAVNDTNDALLTSVIRCRVTLAMSNYTQLTIPITPTYVSYTMPSNTCHVKLHAVNDINDACLCSVIRCRVTLAMSNCMQLTIPMTPTCVSYTMPSNTCHVKLHAVNNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WL52</accession>
    <name>A0AAV4WL52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_564701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016398">
        <property type="protein sequence ID" value="GIY83542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WL52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13262" checksum="7D20C66B9460C3E3" modified="2024-11-27" version="1">MRKPCSDLGGSLLFLPVPDLRILQEKKKGKSAPGMVHLLSSSQDYLQLQTWWNTLIMFETLGKNLDINAEKCDFTIVPRVTLISSTLFSVVTKDFMVRTKQDEIRSGGTFYKSSMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSA2</accession>
    <name>A0AAV4WSA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_729571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016546">
        <property type="protein sequence ID" value="GIY84704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18816" checksum="140C6DA83151ABBF" modified="2024-11-27" version="1">MIIERWNEDRACLVVCRSAGLYEPRCREAHCVGRIISLYKGLVAAELLPFQTPEKHALTEDRMMPKHKGHRFICGRHVLDFEICIKNMSNEKNNNNKRNHNKAMSAVFDVFMLHISSLAKTQSGFMPEKISASIEGGHFFLGIGSNFCRKRQKIVVRVGKSSLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WU93</accession>
    <name>A0AAV4WU93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_90011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016626">
        <property type="protein sequence ID" value="GIY85219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WU93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11616" checksum="AB6D5675146791F2" modified="2024-11-27" version="1">MPVPIADELSETGGFAQMPQRRLRCFRERQDFTDTPAVHAVGGVTGGPFQGAQPQRCIEQRGQEHTIALGFIWGVFIHSVQEGFFHVWMSYGSYSSPFLRAGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVF2</accession>
    <name>A0AAV4WVF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_810791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016860">
        <property type="protein sequence ID" value="GIY86905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12529" checksum="5203DB5301C996A4" modified="2024-11-27" version="1">MHLFIPPHILPITCPLLETATGSSPARRAKCIKLMPLRKIGSLTPVFESPLDHSSSSHSISDGHGPLRRGREAIFLQTIFSGSHCKKDPRGWGERRSLLVIALPGGSYSGFSSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWC7</accession>
    <name>A0AAV4WWC7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_782091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016730">
        <property type="protein sequence ID" value="GIY86025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="21641" checksum="3C2FCF6F97708644" modified="2024-11-27" version="1">MEQGKFYKSKKQSRVAIIKAVHLLQKLNSCSVKSLKRYLANQYNVDCNAVDTSTKSIMKYALDRNILNKLGHTAKISETRSSGRSNRRSSSSGNRNNSRSPGNRRSGSRRSGGRSSGSRRSGRRSSGNRRSGSRSSSRRRSGSRSSSSRRSGSRRSGRRSSGSRRSGSRRSRSSSRSRSPDRSSQRRDRESSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWJ2</accession>
    <name>A0AAV4WWJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_75831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016835">
        <property type="protein sequence ID" value="GIY86698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10205" checksum="7D18B6CD3029931C" modified="2024-11-27" version="1">MLSAHNSLLQMKLIRQSLSTAAPLFRRGNGINENKETCCSFVSVAPECGARWKNQGPTKPTGGESQGQRSRIKAMDGSGRTDHPRTDVSVVYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3B8</accession>
    <name>A0AAV4X3B8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_461591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017235">
        <property type="protein sequence ID" value="GIY89622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3B8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19108" checksum="0DB44500D9E23B31" modified="2024-11-27" version="1">MDASSSSGCLHVRRPYYPQNVIWLQNLGNEFICTAKMSNFDDGLFLLKYIWCLASYFDKSTHCCFPKTYTFQDFYFPDASSVKIGLTQDQESGGIRQFFPLITLSLFVSRALVSMNHLWNSFVIAMDASSSSGCLHFWCLHYPRNVIWLQKLAKCIYWYGEDVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X851</accession>
    <name>A0AAV4X851_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_157921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017381">
        <property type="protein sequence ID" value="GIY91091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X851"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11288" checksum="395012257C400C92" modified="2024-11-27" version="1">MFSFKPCRRRVRIWWKHHESMDVTPLQADCRNVMILAMFSWHALDSLIQVSRLLNKASYFNIGANLVHPIMLIVYPHSNSCFNKIAFMNMKDGLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAV1</accession>
    <name>A0AAV4XAV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_700911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017404">
        <property type="protein sequence ID" value="GIY91325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="20433" checksum="25B53F391E6DE328" modified="2024-11-27" version="1">MSSSGEKYTRSYPFRDRHLENFDTHMGFKKQHVYLVKLNFLLDIRLSRKHSRLLCHAILYTTRHHPRAVVDLKWFPLSLVVPLGAPTATFLIEKHHLNQYKQPSPPPLLAYDCLMVDVSLPTENECLALAPEASLVHLLYEISTVNTLLETYARGAKHFFGARSGERIFELSHHGDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDE6</accession>
    <name>A0AAV4XDE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_42511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017618">
        <property type="protein sequence ID" value="GIY93057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8760" checksum="12AC47E90AE43BAF" modified="2024-11-27" version="1">MDGMGTCAFFISYRIRIPSANHNVSDKQMVPFHNMMQLRPSNVFDVMVSLLWFGDKWWCGSVVKWTSTYSDEHKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDP7</accession>
    <name>A0AAV4XDP7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_354451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000164">
        <property type="protein sequence ID" value="GIY92573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12845" checksum="12B998C0A60B766C" modified="2024-11-27" version="1">MSDFCANSKICKWLLIPSLATSLASRGNDWQLRSGNPLEKDRRSFRWESMMNGQPTQACRGSCGGHLPSPLLSVCYILGPQGCSTGELVSKERSARVAVHTAFVAKEEKGPRNSEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKI1</accession>
    <name>A0AAV4XKI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_490771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017952">
        <property type="protein sequence ID" value="GIY95691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10655" checksum="E355575F9BF43A2A" modified="2024-11-27" version="1">MFQESFAPLFFPDLWVGLAGRTFLDPWSTLFHLVQVPFLRVWRELFWHEFKVVELFVVVVSAPPVLGFCVLRDFMALHRIEFLQVMRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLH4</accession>
    <name>A0AAV4XLH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_204901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000540">
        <property type="protein sequence ID" value="GIY95544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16440" checksum="AFF5B1DD65C063A1" modified="2024-11-27" version="1">MLRLLSNQYKIIRFDIQSISNATSERKSISTFTYLNDPNDGKEINAFRGKSRKQSVSLTADGTWRRSGLGEGWGNPSASCFRGFRAGTSMRKKSDGNETTNEKNNRDQHHDGERTNEINTTMERDKRDQHHDGVRTIAINIMME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLS4</accession>
    <name>A0AAV4XLS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sterol O-acyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SOAT1</name>
        <name evidence="11" type="ORF">CEXT_206111</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017981">
        <property type="protein sequence ID" value="GIY95936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF8">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY95936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="385" mass="45326" checksum="F3BAD819D3635FD2" modified="2024-11-27" version="1">MAPHASSEETDKTSKEINKNADTVHWKQNASKKSSLPTKVFVHRNSVLTDLMEVNHLQTVYNISVAFVMLLLLNSVMYYIVLRDMKLIGWAAANVQLFIKCWISYHVLAFLVLYGFKTWIRVRNKINTKIADFVFLQMFIFASILMFVVTSYAMVTNGFRITIHLAIMSEQVRLYMKIYSFVRESVPRVLNYKPSKDGKQEHVLYPTASHYLYYLFAPVLIYRDSYPRTFAFWRQRLYQDWWNSTSFSEYYRKWNAVVHDWLYTYVYMESINAGMGRSIALVTVFFVSSVFHEYILSLSFGFFYPVLGVVYLSVGVPVIFLTKKKTSQLWNTFMWSMLFAGWGFVVFLYSIEWYARANCKGTEDPILDYFIPRSWSKSCHILSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM41</accession>
    <name>A0AAV4XM41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_740961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000568">
        <property type="protein sequence ID" value="GIY95732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12519" checksum="3D4D7C70583D562D" modified="2024-11-27" version="1">MYTAIRQEDKRQQCLFTGYVSFPHYVEKGHACYWAVFKKDYFRSLNNIRFRVSIYISDSLHKRKTFIHSCFPRVLIPLCVSSFGSTQDFCLQASRWRQTVWQCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP29</accession>
    <name>A0AAV4XP29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_270431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018085">
        <property type="protein sequence ID" value="GIY96761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17509" checksum="7E16C1F6EBEA0665" modified="2024-11-27" version="1">MHDKRFPRCLEFTPFLPFAFLASLKLATERIFGAKNALNERKWQTKECTDLAFADDREVTTDMGVLRPRPTKKKPTGRARTHPGIRPVSSGGSSGGRRRGFGRHGSHHCHRHEDTESTTPKKFMKRKGNLKKRALMIMDPTCPHSHLVRLWHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUV1</accession>
    <name>A0AAV4XUV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_490491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018343">
        <property type="protein sequence ID" value="GIY98831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY98831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="221" mass="25791" checksum="7A9FD343391EB561" modified="2024-11-27" version="1">MYRNSGIKGVRPQKNRTKKKRKDSIFSSLIKSKEQVPFSGLKHSRNRAIFQSQELRPSEGRFPLVTIFYWCIFLGFVSEAIVLGESIPERKYWNIGLKKCAKRTKQRRKKRQYFLLSKEKNESLFPDRSISKMKRSSSRRSSFRVKIAFTGQCFLPVFFLALFQRPLCRERVKFVIVLRTIHLSQQRASVIERARSLTKLGIGKNTIFTGSINNGSKLTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XV68</accession>
    <name>A0AAV4XV68_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_198561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018191">
        <property type="protein sequence ID" value="GIY97638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XV68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831416" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10838" checksum="DDFD24CF659A4512" modified="2024-11-27" version="1">MYRSYCRSILLWIVLYASPYSFFPSPCNGGRVKGGRAMRTQKSVDPRDVGGHASHPTRTVRRRKRTQTAIASGVRRHGSSETRKTGAPFDEDGPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XV83</accession>
    <name>A0AAV4XV83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vesicular glutamate transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">slc17a8</name>
        <name evidence="6" type="ORF">CEXT_738781</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018212">
        <property type="protein sequence ID" value="GIY97774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XV83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY97774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="319" mass="35578" checksum="D8527894C0271790" modified="2024-11-27" version="1">MTEYSVEVNIEEHQNQGVTFPTLTSLIAYWSPEFERSRISSVIFSGTWVGTVISLSVSGWLCSMDFLGGWPSAFYVFGTISCIWFSLWCIFVYETPFKHPHISKQELLLFKDIQSTSKIIKMPWCDMLTSIPFWILLVAFIGQYFANIFLLLELPTYLNNVFHINVEKNRTLYFSAGYALSLAFIAIPLSGCQFSVIVTLLCLGWFINGSHMSGFNIVTVELCPDFSATVYGICNGIGSLTGIVAPNLVGVLTKSGPTVANWGKVFYITASLLSITTTLFALFASAEEQHWGEARYTKGIRKSQVNTSVAMETKNTVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVG3</accession>
    <name>A0AAV4XVG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Netrin receptor UNC5C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Unc5c</name>
        <name evidence="3" type="ORF">CEXT_29411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018387">
        <property type="protein sequence ID" value="GIY99126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005042">
        <property type="term" value="F:netrin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008045">
        <property type="term" value="P:motor neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08781">
        <property type="entry name" value="Death_UNC5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.533.10:FF:000092">
        <property type="entry name" value="Netrin receptor unc-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037936">
        <property type="entry name" value="UNC5A-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033772">
        <property type="entry name" value="UPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12582:SF47">
        <property type="entry name" value="NETRIN RECEPTOR UNC-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12582">
        <property type="entry name" value="NETRIN RECEPTOR UNC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00531">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17217">
        <property type="entry name" value="UPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00005">
        <property type="entry name" value="DEATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Death" evidence="2">
        <location>
            <begin position="401"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY99126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="471" mass="52417" checksum="0CE909F9C334E006" modified="2024-11-27" version="1">MSDNYKVIPVQPDLTQTALVNGVQINGGFGEKLVTPLLSHHFPIPPSPAQSRAPLLDQQHQQRSLTPSSTGKPPHSGSCPSVVSSSASTVSHPSTISDNETPSGRHSVTSAALPPNLDIECIAWELSPKVVGVLPYQGLSRGAVWSVRRGAEKICHHHFPAQCLAQLQNWKINIQASESGTEEREPGVEERGDPGQGDHQHPLYCQLDGRQCHVVTDHLCRYALVGETEESGGWAVKSLAWQLSPLPCIPQANLCLCLEDVALGWRCKPGANYQEIPFQHVWNGRQNNLHCSFTLENVDRSQKVRCHILVYQRGIQAHRQMLKVNPQDIREKCYNDYYCLSESNVPSPTLTWSSQPLSSTVTANDNGSPLVALDQPIAGFRLTQQARKQLRTFLDPPNLNGNDWRRLAQELQVDRYINYFATKPSPTEHILDLWEARHRDSSAITDLLNILRMMGREDAAMVLEKEAGSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVI0</accession>
    <name>A0AAV4XVI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_409091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001017">
        <property type="protein sequence ID" value="GIY99175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16020" checksum="DC4D55D62D4516CD" modified="2024-11-27" version="1">MKILLLPTFPLKLATKQVKGITQYFGYHFPDIKLTCQDYFPTQSCGGSLQQFSQQVCALHFKGDHIIPLIKIFIWEVENNLLPFLWKPCINIAGSTQYDGSIGWGIGRAGNYPVAVERSLVGVSAIMLGCFYFAIDIGFLTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ87</accession>
    <name>A0AAV4XZ87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dscam2</name>
        <name evidence="4" type="ORF">CEXT_317481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018538">
        <property type="protein sequence ID" value="GIZ00407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="45"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="148"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="251"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ00407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="464" mass="52130" checksum="B65D24D39E137877" modified="2024-11-27" version="1">MSSNKKVSSLTIDPIIESSGGNYSCVVSNANGRDHFSVVLLVIAPQCGSKEPEDADVIENQNLDLKCTASGSPNPQIMWRKINHAHDDEFPSSQNLKTRNGSLLLEPVLKFHEGHYTCSADNGAGQTLKKTVAVTVRDFPKIQPFQFPQYIQIGYKNKHYVHDYTRNLKIQKAFEGEHVSIHCVATGFPPPNIRIWKLDEAEMKYFQNNVNGSLSFKPVHKSHEGKFSCEADNGVGSPLRKIISLVVHVPPSWIKEPQDVETVEGHKSVFICLASGSPSPKVMWRKIGMLEKETFIYQDFIETMATELYRIFNPTSRRGRLLRVRGSQWNWREFDKSSSSYSSRESQDTALPVSPEHSTGRQDERHLHDHGGDKRQQCTSGTRALMKHPKNNIVTTISKSNQSTANAHLLLNHVLKSHSGKYVSPVQWVSEPVNREVLLGENVKFSCSASGFPAPTIKMEENIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZL8</accession>
    <name>A0AAV4XZL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001031">
        <property type="protein sequence ID" value="GIY99318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17696" checksum="8C41BCB62A85F77C" modified="2024-11-27" version="1">MSRGFEGTPLNLFETQDRMSCELRTLSAGALGRGALLLIPFRLNSSAGMGTIRGRGVKRRNKKPINSKLIFNTSLTALPSITVNPTVNITLLSWPVQVTRSLNLETSTFNHFPLLYILPAQSYAFQPILRSIAFNLRCHFTQEFHPLKVSWTFGENTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1I7</accession>
    <name>A0AAV4Y1I7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001088">
        <property type="protein sequence ID" value="GIY99840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1I7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="231" mass="26004" checksum="E30AB2253B679BB3" modified="2024-11-27" version="1">MDKYYIFLNQFISEFLHQEGTARWCQMKDAMCYYQDGNDSRPENCAQGRREDADAIIVGITWVGSELLRFMPDSVSSRGGYNGFFSLIAVTHFWDYLCIFSLSDRGWCLPQVRAPDIAPKKVQKDLLPGKARSAMCTSCKQKGPKHRCSTSSNEKLFLLPNSDPARALEWGVGEAQHTYVHTYAEKKKVLCVCTFLGAEYRKLSIPLPQLRKGSPGAPSLEECWAARAVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y687</accession>
    <name>A0AAV4Y687_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_808681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001454">
        <property type="protein sequence ID" value="GIZ02404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y687"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8472" checksum="BFE548BDD557FD07" modified="2024-11-27" version="1">MPIRWMTGMIGRTPAQAQSRFRRPLKGNVPAANGMASLTTAYQSSQYSKQTDIDRLKMELELLQLFLGLLFSIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y896</accession>
    <name>A0AAV4Y896_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_696701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001447">
        <property type="protein sequence ID" value="GIZ02377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y896"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="321" mass="33776" checksum="DEAA44A5A91C7B49" modified="2024-11-27" version="1">MASMSEERRKEMEEEMSRFELEIAAPSKPKSSGNKPLSPPPPPPAVAVLLPEVLGPPPPPALSPPVGTTLQAPPRLPVLHAQPATPAMRFIPHQLQRQPPRPPMRSNFMGMRGPPAPFPPPGSFGPHMGQGPPMPQVGPMPPRGPMHPGGPMLPMPPGAIPMQPMPHQMGAMNMGVNLPVPPGFCPPGPPIGSSTNMMYESQTHTSSASNTETEPSMTTSTAKSSESSVVASAPTIYAAPFMKSSENAAEGLTSGNGQETQVTSAASSVAPKLEKVSVTKVSRETSAVPTASGITEETVVSKKKEKKKKDYPHGWWASVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9P1</accession>
    <name>A0AAV4Y9P1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_214461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001688">
        <property type="protein sequence ID" value="GIZ04063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10606" checksum="D57DFB3D5A2B484A" modified="2024-11-27" version="1" fragment="single">SSVRRASDLWIPAIHRYSPPLCQLSYRRADGTQRLKKVHSVRRAESNQRPMDTTSVEPESRPSTYGYQQYTATVHRSANCSYRRADGSALIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFP6</accession>
    <name>A0AAV4YFP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein MCM10 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mcm10</name>
        <name evidence="11" type="ORF">CEXT_146081</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019154">
        <property type="protein sequence ID" value="GIZ04851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055065">
        <property type="entry name" value="OB_MCM10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015408">
        <property type="entry name" value="Znf_Mcm10/DnaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22379">
        <property type="entry name" value="OB_MCM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09329">
        <property type="entry name" value="zf-primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM10 OB-fold" evidence="10">
        <location>
            <begin position="150"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger Mcm10/DnaG-type" evidence="9">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIZ04851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="315" mass="35963" checksum="2E1C9D05D0BAB86D" modified="2024-11-27" version="1">MDQSEEMDIDSLMELLDEPFEEEPVVTIQINNNFTSEKINHTKELKDKIRHDFLTPMLVENPKPEEPYIKPADLLKDSVIHSGETDSSDEESQKYLSECGLDIKKQIKQKFNHSSTRPAIPSVSTWKSHVKSSNNTKKPTAENSFIVDSYSGIRIINPLVSFSSLQQRMENRRMIKMSFIQNFIKNGDIEGDWVTMGVIVQKIPPKTSANGKTYSIWKMSDLHDIEKILSVFLFKTAHKDLWKTTVGTVIGILNPSIMSNRDVFAKSKRKDGTSCNVAVNMLQCEYCTYHIKKNTRNLVVSAVNFILHFQLKTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3X5</accession>
    <name>A0AAV4M3X5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_101431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019379">
        <property type="protein sequence ID" value="GIX67162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043808691" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="12299" checksum="1546B61EB592082E" modified="2024-11-27" version="1">MWYFVLIVFGFWNGAFSANQTCIENLGYACSNYRMIPNEFPGTEDELKEPCTELESIKRCLMERLNECDSNNYDDLVMARSDLPGLIATLTEICQEDTELHACKLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5H9</accession>
    <name>A0AAV4M5H9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_82541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019331">
        <property type="protein sequence ID" value="GIX66656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5H9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="30" mass="3358" checksum="D6DF701B75693873" modified="2024-11-27" version="1" fragment="single">MAVVPEPDSSIGGNDTWHLHMARHQTCCYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M816</accession>
    <name>A0AAV4M816_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_31147_1</name>
        <name evidence="2" type="ORF">CEXT_102741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001976">
        <property type="protein sequence ID" value="GIX68566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M816"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22727" checksum="2BE5AA805BAAE251" modified="2024-11-27" version="1">MLYAYAHATFFMLTFANGLITMMFVSLLSYKIYYDLSDIMNEYRRSLLKLIINNYIDELSIQKCLADYRLIVDCIDQVETGFSGLTLFWLDLIAGKNLSRRRCLEKLVVRFSEKAAYNFYVDGKICLPKLHCFGLLAETIRGTTLELSGGNLFVLKYNLILSVIGLMVTYGVLIFNLNNFDVHDYNKTNASHMIPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M979</accession>
    <name>A0AAV4M979_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_580101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019515">
        <property type="protein sequence ID" value="GIX68702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M979"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9917" checksum="917624D051661D19" modified="2024-11-27" version="1">MTPKEKNMSDSEMSSMQVILKQLSEIPEETTAFKQDPFHCIFKNAFIPKCMLTKSRTKGARMEPTRAHMEQDPRVALRTLVGKTSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAS4</accession>
    <name>A0AAV4MAS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_88581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019539">
        <property type="protein sequence ID" value="GIX68988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11564" checksum="C545F9F9795004C3" modified="2024-11-27" version="1">MQQKGRECRFHNTADVCRTLKFPFADPQMNDEIIRSHCLSRITRTQNCRMQNFAANRRSEMNVATGLFNYCVPNLVWPNDWKVGVANNIPNCLTNGVQFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MC86</accession>
    <name>A0AAV4MC86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_165821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019640">
        <property type="protein sequence ID" value="GIX69991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MC86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9325" checksum="72FA344EC3C1FD52" modified="2024-11-27" version="1">MFTGGKKRKCQQTCTQNVVYGETKRVYCDSGEKTKVFIPKNRKECATVFLKFLLILQEFRCTLVGGSDPRLVGFRLKQSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDR5</accession>
    <name>A0AAV4MDR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_59261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002101">
        <property type="protein sequence ID" value="GIX69990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="15021" checksum="7DD576DFD92F746B" modified="2024-11-27" version="1">MGIMVWIYVQWIKTYLLFGYLWVLWFGYMSNGSKTYLLLDTYEYYGLERYPNHRIPIHSLTYYGFLRNTSNYVYISYGLDTYGYYGLDTYGYYGLDTYGYYGLDRCPMDQKLFTLWIPMDTMFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFG1</accession>
    <name>A0AAV4MFG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_527391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002181">
        <property type="protein sequence ID" value="GIX71020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="338" mass="38538" checksum="382E923CECCBFFFF" modified="2024-11-27" version="1">MNISIKMPKHAFNRPSTYTTNHESSKCDSKFMHANSDKGEICYGRIWSEESVSIEQASNPSRVIEEPMYFNIEEINSMEKMNDSNLSGNDVVCGEETSDENLNLRKTEYRTHYEDSTRKIPKEFSTSSPLEAAINRLPRSFNVKSLISKIDNPVLVQAEKSSRFSRQLRNIHRASFVPQSTFVDACGEETSDENRNLRKTENVTHYEDSTRKIPKELSASSPLEAAINRSPRSFNVKSRVSKINNAVLVQTGVSSKLTRQLANSNNIHRTSFVPQNTFVDHSNSSQTKHDESLPSNPFDLTTKNSSRGRDSSKWRRSNKLGSNQNSSSWKRQRCIFWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLV7</accession>
    <name>A0AAV4MLV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitinyl hydrolase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_785551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019891">
        <property type="protein sequence ID" value="GIX72949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13697" checksum="E82F6825CFAE0E9A" modified="2024-11-27" version="1">MGLCDTYGTLCELIAAAQVFPFVFEVWNAGTLYYTTAVHNRADVPTKRLRFTGNFSGGHFDVLEDAETKKESAIEDDVFRPHHGKNIRQQGDRRCKRIYENRARRSARRMSRSVAEKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQ15</accession>
    <name>A0AAV4MQ15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_556461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019967">
        <property type="protein sequence ID" value="GIX73572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQ15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="203" mass="23026" checksum="C56D8FBEECC03C3C" modified="2024-11-27" version="1">MYHKIKLSNTLLHLSINLNCHQCLQVRFSSSTLRKPPGPPFQSSNIQQYAIPSPMPQAHSQSFDEVPVMHGRAIPHQYEALPQQSNYPYLPPRLPGEGMFKDLKATVNKLFGDKHMMPPGFMNKQNNEKWDSDHSNAPFLAHHYDSGGPNRAMGSGKDLERHPRGPMEYEDNLSVHSNMSISDPHISNERMYVPPPDTKVSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX97</accession>
    <name>A0AAV4MX97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_46361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002723">
        <property type="protein sequence ID" value="GIX77137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10763" checksum="6196A73ECDA71198" modified="2024-11-27" version="1">MYNKLGRWEVDFNGDRTVVTKHLKDMSTSIGAWPTPVRNVIHAQHPLLGHNNVCIYRHVQHRVSISMQRIPQDLSDAERSLLSLGHGDVAEPRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXW3</accession>
    <name>A0AAV4MXW3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_66951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020235">
        <property type="protein sequence ID" value="GIX76167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10482" checksum="1E640B8786AABF64" modified="2024-11-27" version="1">MRLNRFDGMDFMVFVAIVPSRLCDVQTKRELIQTRSFHLRYNVENVIWSYSQPKLRLLLDVKRRLVDIFRQNIFLSNAMPHSYFSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N046</accession>
    <name>A0AAV4N046_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_156831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002710">
        <property type="protein sequence ID" value="GIX77021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N046"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12463" checksum="A9679CC6C73B32CE" modified="2024-11-27" version="1">MSLMRSEIVPLIDGDHRGVSDSTVCGSTKILQKPRQPHLRRNTLESFCSFQSFSFPSLGYIPTFSLADKKSTVIKSVTDAGSLEVPYLRIVEEEEKKKKKKEGLSLRYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N1H1</accession>
    <name>A0AAV4N1H1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription initiation factor IIA subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_274761</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIA subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020428">
        <property type="protein sequence ID" value="GIX78579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N1H1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07976">
        <property type="entry name" value="TFIIA_alpha_beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.100:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004855">
        <property type="entry name" value="TFIIA_asu/bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03153">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01371">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX78579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="44386" checksum="16FAE5C3C905DB6E" modified="2024-11-27" version="1">MESLEPKLYHSVIEDVINNVREAFIDEGVDEQALTELKQVWEKKLQESKAIEREEAPVTKIVTQTPIQPVPQATTIGGTSATITHQLAMPTGNMIPQALLQYTPGTNDLQKTLHMPGKVTLSLPAHMAQTGLQTLVSGPGTTHVQLPPEFASLFQGNIITSAPNTLQQGSAPLSIITKPNLICGQPISGVYQAITSDQLKNAQQFTVTIPVTTQQSQQPSVVSQIDGANDTSDDDDDDDFPDNDDDRDDDNDDQNEDDIGEEDEEPLNSDDDVSEEDPSDLFDTENVVVCQYDKNHSKQKPVEVPLERWHHELARQRFCVPKGSWGLRVVAPASSLAMTILIIFIHGCRSSHCCTDIILHAAFRCCRGNYYFLSHFIVNKYVVNFLDVILNAYRFKNMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6D0</accession>
    <name>A0AAV4N6D0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_714051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020477">
        <property type="protein sequence ID" value="GIX79241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6D0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10599" checksum="68EFD17FB864A573" modified="2024-11-27" version="1">MEEKFPEHRWVRILLDGFQIDDVAGADVYSELFSHAALQRWIVGVGSMESNLFGGQFEIAVQCFCTVGTISSVIGLKIRYRRFCKVLAVSSVVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6G6</accession>
    <name>A0AAV4N6G6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_413011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002997">
        <property type="protein sequence ID" value="GIX80086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6G6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="12970" checksum="C60B6FD92F0BC828" modified="2024-11-27" version="1">METVLDITIADSIAAQCVIVKNISTPLFSGSFESLIIQRKEITLGGLEVLSRFRSGYFTTPPSRGAFTVVLPTSRGCSIPHTKIRCLAPEYLRNCVIAVMATICEKAAKAKPGYGNACSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7I7</accession>
    <name>A0AAV4N7I7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_265091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003064">
        <property type="protein sequence ID" value="GIX80812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7I7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11506" checksum="4633B0AFCE7CB30B" modified="2024-11-27" version="1">MEINLNALSVAGEDNCDLPESFTSTSFDLDQFSSWSNFLSPFRTISETPVIESPIQMDTLNTSSVMSSKIEDQPGSLVKPPPTLQRPVPSQLSLETIRTSRKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8U2</accession>
    <name>A0AAV4N8U2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_399891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020621">
        <property type="protein sequence ID" value="GIX80745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8U2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11429" checksum="FCE180DFEFCF3AF5" modified="2024-11-27" version="1">MWVKLFPFKPSSHLPSFGIPFERSSAVMEFVHRDRNSRQLRNGERWRAEEPPSSSTAHPQTNREKATSYCRLDQGVLEQKTLISFPAMAAFHVNVCNVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NC12</accession>
    <name>A0AAV4NC12_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_21101_1</name>
        <name evidence="3" type="ORF">CEXT_241141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM154 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020657">
        <property type="protein sequence ID" value="GIX81191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NC12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036126">
        <property type="term" value="C:sperm flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033336">
        <property type="entry name" value="SAXO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516:SF17">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX81191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="296" mass="33369" checksum="4C0AD2368ECCEAF3" modified="2024-11-27" version="1">MERVIRKSRVHEEPATAKKGTLTKLGQPFKGITETATSYQPPPLAQRELCLPPKGELRPEGDFEGITTHKADFTPKYQPRSKPCKLESKWKRGDPGKFEGVTTHAYDYKCPPVPEKPEIIKPTGNLQTSEGPFEGVSTTREIFLHMKQHCEYYLNGTLPFNGARHQMGQCLDKTYRTDFEAPSEELQQPYQKKPLKHNLTILAGKFSGCTTTHCDYTPKMVEKPVVSKVPDNLGPEDGPMEDLTTSMRDFQGLGIDCPLNTSNCTVKEALPQYKFDKTEKGHDFFKKLKKSKQSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ND87</accession>
    <name>A0AAV4ND87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_654351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020767">
        <property type="protein sequence ID" value="GIX82305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ND87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10832" checksum="753AD7507EFBBA54" modified="2024-11-27" version="1">MSPEFTSSLLTNKPTAWIGDYRNIKQYLLENPLPSTRCISQDLISTTTIFIPVTALKDPSPTRPLFRPPPSDASLLPRNRESRKADDEDQKDGGSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKJ9</accession>
    <name>A0AAV4NKJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_643841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003415">
        <property type="protein sequence ID" value="GIX84348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="223" mass="25496" checksum="ADE14DD9FB50AC8F" modified="2024-11-27" version="1">MSENVDLTVSPVKEIFHKNDSTNVKKSPKRKTNKKTRVSKNNNKNAFHLANSSMEKESISKKRIEMPEDTIPSTVEDNVDECESVEKELTKEQAIESENVFEESVVLSNELEQDHSSDINSVKQSRVVNEIPENNDDNFTALNEPIHKSDGSYRSKIQNKKNQNDDVNLFLDGNSLMNKNKTIHDGYVKENVTDFTENFKKSSILDERNCNLENRKGSTLCRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM85</accession>
    <name>A0AAV4NM85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_271781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021106">
        <property type="protein sequence ID" value="GIX85907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="62" mass="7138" checksum="F319212EC5CD97CB" modified="2024-11-27" version="1" fragment="single">MLPDIGTTKKDAQEYLTFLKKRDVAQHLYDAYAAALTCHSPDDDYLKRIAILHDELQNAMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRR9</accession>
    <name>A0AAV4NRR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alcohol dehydrogenase class-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_342751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021156">
        <property type="protein sequence ID" value="GIX86601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="8">
        <location>
            <begin position="34"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="7">
        <location>
            <begin position="201"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX86601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="374" mass="40066" checksum="AEE71B55274D368F" modified="2024-11-27" version="1">MATVGKPITCKAAVTWEVGGGFKIETVEVAVPKKGEVRIRMTSTGVCHSDLHVMEGIDKDWPFPCVLGHEGAGIIESVGEGVTSVVPGDIVVPVFEGHCGECDFCKDPRTCMCQKQTRNHLQMDGTSRITCKGKPIAQMSTISTFSQYTVTNEINVAKVNPKANPNTLCLAGCCIPTGYGAVMNAGRVHPGATCAVWGLGGVGMCVLMGCRDAGASKIIGIDTNPNKFPLAKQFGATEFLNPKDVSSVPEKLAEMTNGGVDYCFVSVGITPVMEQAFMSSHPQWGKTVIIGLADIGETMKAGIWELIYGRQLVGTFYGSYKARLGIPDLVDKVVSGQIQLEKLISHRLPLDKIEEGFKMLTTGESLRAIIDYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NU15</accession>
    <name>A0AAV4NU15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_791131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003662">
        <property type="protein sequence ID" value="GIX87213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NU15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14188" checksum="F8C32534D9599848" modified="2024-11-27" version="1">MASLPTIYTLCIKARITCDSWGKNDSWPVSRAELWPGHFHAFSKPGQFGRNIPSQTARTVNFRAPSRLKFFGFSSSMGVIIKSIFSVKIFQLVSGESVDGVQKSPVDLKLIWGADTIGPPPKWTVFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NV02</accession>
    <name>A0AAV4NV02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_457671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003778">
        <property type="protein sequence ID" value="GIX88543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NV02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12331" checksum="2DF6B19A7544D60F" modified="2024-11-27" version="1">MIKARKGAPDQTRNVLQFHLKLKELRQCYRKKHNSFYITFSCSVEGITSSETCMAFNVIRQQSKRFFWLLNYIMTKAFNDIMNDYYDELPKPMSDHQSANHAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P095</accession>
    <name>A0AAV4P095_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_201421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003878">
        <property type="protein sequence ID" value="GIX89631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P095"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="13008" checksum="4BF69BCE05DA8799" modified="2024-11-27" version="1">MYHKQCLKIYVGNNRFANCAACHRVLTSQDFKQIGIRVPVVRQFQRRDLFENPPRQGPEEDASDEGYESGDYDTRAFQKLVQKRFLSEQERRRLRMPRERQDEGYTSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3R3</accession>
    <name>A0AAV4P3R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone H1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_152231</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021566">
        <property type="protein sequence ID" value="GIX91215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000140">
        <property type="entry name" value="Histone H1.0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF20">
        <property type="entry name" value="H15 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="9">
        <location>
            <begin position="30"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="131"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX91215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="19494" checksum="6DDF2BC6364144EA" modified="2024-11-27" version="1">MAETEAVATPAATPKKAKAAKPKKPKTAPNHPKVSEMVNTAISTLKERGGSSLQAIKKYIGAHYKVDVDKLSPFIKKYLKNAVVSGNLVQTKGKGASGSFRMTTTTKEKTAKPKASAPKPKKVAKPAATKKAAKPKAAKKTVAAKKPKPKLAKSPKKVKAVKPKTPKPKKTKAVKKATPKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PF52</accession>
    <name>A0AAV4PF52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_160521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004586">
        <property type="protein sequence ID" value="GIX95962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PF52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9313" checksum="AC749C39D32569AE" modified="2024-11-27" version="1">MPPKMEIGGTRDHKQSILEELFSLHSVFLFVSFRSLTEGRLLFDYRAFLHGPSIHLWETNEEALRNDPEADRRSTPVQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHM6</accession>
    <name>A0AAV4PHM6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004662">
        <property type="protein sequence ID" value="GIX96571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="15439" checksum="B6586238B8BFD1B4" modified="2024-11-27" version="1">MPKIKHRTLPFLKSRVTHYFSFTDENTDKTQSQRLPHSYQQRSFQNEVTTFSELYEDLQLQCHFKPSKNVYLRLGKGALRSRSYYKVDNRHEIMLFYTGGIFSGFLPYTQCEMITANTRWAETRLRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PK69</accession>
    <name>A0AAV4PK69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Craniofacial development protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CFDP2_1</name>
        <name evidence="2" type="ORF">CEXT_255341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004534">
        <property type="protein sequence ID" value="GIX95577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PK69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16786" checksum="100CA2BE1778990F" modified="2024-11-27" version="1">MGVILKNLLEKNDNFKDACKIMNQQTPLDSIFVLRLLFQKNAEKQNKPFHVAFLDLKPLYFGIQHPKLFRELEKCGIHKALIGIVKHLYSLNTFRLVTHNKLSEKFTLCKGLISQCSLTPTLFKMYIRETMKIWSEEKPSKWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUT5</accession>
    <name>A0AAV4PUT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005309">
        <property type="protein sequence ID" value="GIY01373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10317" checksum="AF9EBDBE759B269E" modified="2024-11-27" version="1">MLDEFFQKAILIGEGTAYVEPTRATKKSRHEDLSFRTQRFVQQAVFLSFSSSSKAPSPSPTQLLMKTSSSSAAYHLLFAAQRFFHQQIEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXN0</accession>
    <name>A0AAV4PXN0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_638171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005374">
        <property type="protein sequence ID" value="GIY01837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15196" checksum="D98898FDDAE8208A" modified="2024-11-27" version="1">MMELISSAIDSHVPGKRNRKKSHKGLKYIKILKYALPDKSSSTDPWIGMDNLINQNSKFAIYSVGLSENTKKMLIVAAFSHNLSQKEIKYAAPMKVLTFISRSKTKKGVNKRPGAMASDIRELAVRAAFKKVEQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PY34</accession>
    <name>A0AAV4PY34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_440281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005283">
        <property type="protein sequence ID" value="GIY01221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PY34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9896" checksum="69E7071850674897" modified="2024-11-27" version="1">MHIKVATQLRSIQAAATEVKATTSTESFMSTISHFIEFPSQSLGFNLIEYFRRYTDKRVDALSPSYYTIACFEKICKSNGSRFQMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBJ5</accession>
    <name>A0AAV4QBJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_155911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005923">
        <property type="protein sequence ID" value="GIY06074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12067" checksum="6EAE11FDC1E21D45" modified="2024-11-27" version="1">MEFFHSPSKRTPLSDPLPHQQVNGIDWGLRERLSPPAHFPFSNQEDLRTWFFPPNATLINGSIFHVAFQNECPPSNCNRLPNREIGSLLLWLQRINNEQKMSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHR6</accession>
    <name>A0AAV4QHR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_738811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006404">
        <property type="protein sequence ID" value="GIY09593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10237" checksum="9967539224AA3BE1" modified="2024-11-27" version="1">MACFNSKAHQWGVTGAVHAGLIIFIMFIGRHRVLWADFIDFLFDMTLSQCDICSSRQNGAAVAKIFSYQWSWAIVQAHINRLIHQQLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPK3</accession>
    <name>A0AAV4QPK3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">WARS1</name>
        <name evidence="14" type="ORF">CEXT_384191</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01006637">
        <property type="protein sequence ID" value="GIY11340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000033">
        <property type="entry name" value="tryptophan--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY11340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="30224" checksum="268FBD53503CFE9B" modified="2024-11-27" version="1">MSAAANDMNAIKPTDNGYKETENSSNDPKDGDIVDPWNVVSNSQSGIDYDKLIDRFGSSKIDEKLLTKFESVIQKPVHHLIRRGIFFSHRDMYEILKRHEQRKPFYIYTGRGPSSGALHMGHLIPFMMTKWLQETFNVPLVIQLTDDEKFFWKDLTVEKAQQLAIENAKDIIALGFDPDKTFIFANFQYIGQCPAFYQNITRVQKNVTFNQVKGIFGFGNSDCIGKISFPAIQAAPSFSSSFPDIFGNQKDIACLVPCAIDQDPFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTQ7</accession>
    <name>A0AAV4QTQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_328951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006859">
        <property type="protein sequence ID" value="GIY12855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9619" checksum="A4102E794C5B7929" modified="2024-11-27" version="1">MTDRLMRRKDCKSFKNAQYMKFQKSISASDFSEAPTQSSIPGTPDPRRIRKGFSQDFPLPDSAPSDRRDGHERQCWQNCRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QU35</accession>
    <name>A0AAV4QU35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_338951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006898">
        <property type="protein sequence ID" value="GIY13168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QU35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10702" checksum="FC03402AF4DAC29F" modified="2024-11-27" version="1">MQSKQNFDFVSPWQQRPISSFRNSDMLVREILDQSEELQQLVQVTFTSYSNKQSCGSSYTTRKSGSYTTREWLLHNREWLLHNPRVAPTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QU97</accession>
    <name>A0AAV4QU97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_752161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006678">
        <property type="protein sequence ID" value="GIY11666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QU97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10607" checksum="645BF1B7F094380F" modified="2024-11-27" version="1">MRESKYVGINVFETHKQYLNLKSSTAHTKKTLQITVIELFAVNLNLLCWDENEIGVAWSKSVRVTELKVPSTAIFGESVTPSAAMTWAVRNFMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVK1</accession>
    <name>A0AAV4QVK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_96097_1</name>
        <name evidence="2" type="ORF">CEXT_149781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006776">
        <property type="protein sequence ID" value="GIY12351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="580" mass="62639" checksum="D7ED57D63F76E6A6" modified="2024-11-27" version="1">MSYRLVFPLQAQEEGAELLAVQDSPPGSMRHGGAAGITYDDVLINHHPTRLPNHLNPDTNTLTPIELLDVKYGNYVQQHADPLTRTNFTIPSGANNTNQQQQQQQAPTERQRQHRQHHSQNHHHRSGHHKKKDHQFHPIYEEVSATSDDNKVGGRSYDSDIEDSEVEGRTVGSEDEFAEDELSVAGEYPLNPEESQPCSATSSLQGSTGGDLYPDVVTGSSERFCSDGSPSDARTLKSNFRCMDMGSGHNKLTHSLERNKDGHPSNSFQAKQNYYLNKSMLGPDFTYPDGGADGNSCVSPSGDMVQQSDQSQYPPSRAMGSSLNFIPALLQQQQQQQRGGPMPSRSASNSPPPPPYASSTNPRPGQGSSNSGIISALYNPQIVSPGNQQAGRIPDALLRELTFKMPSPNCGGGTLPAVAPMSSRSLPVPPSCRAGGSGVLFTVENPYPVQQAQLPSLSRTRSGSATEFTTTGGRGGYPQYPHHVVGGGRPPTPPPPENIYASIDDVGPFTIDGGRHRSPFVPGRKNSGEQRNTFGRSVGRGQKSSGEKFQANNVPNRHPNNEGGSYGDIRPIYDSRTACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1G9</accession>
    <name>A0AAV4R1G9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_57971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007015">
        <property type="protein sequence ID" value="GIY13908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1G9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10708" checksum="C93A6D822F32EF34" modified="2024-11-27" version="1">MHDSSPMHGFVAASHQCMDSSLLLTNAWTRRCFSPMHGFVAASHQYGFIVALLTVHGFGLIRLLLIVMDGPVHGFVAAFHQWIHECTSLVVGLVAAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R966</accession>
    <name>A0AAV4R966_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_99021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007521">
        <property type="protein sequence ID" value="GIY17536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R966"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19664" checksum="02DDDFAAD2DC6A8F" modified="2024-11-27" version="1">MPLNDHKPSVEMMSDYYSCCCELGKLLFREVMVSSELWRTISAKKERRREWRRNVIVFGKALRFVRNRVGRFRRPDAELFIASCPLPLGGGTHVGGIANNGAKQRMPKKASLLLPSLSLGSSRKIVSGIQIGGSSRNLLRRVSPLGMLISPRVGSNQMNSTKWQTIVLGRYRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJ99</accession>
    <name>A0AAV4RJ99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_443311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008101">
        <property type="protein sequence ID" value="GIY22069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJ99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10017" checksum="07B223F2B314516B" modified="2024-11-27" version="1">MMTTFLLYRHQIHQVAIPSKKLDMLIMKEASVRFERWHLLEVYSIFSKSMEGPTRFTDLPCLFLALIARTQRVPPFQKFNKPGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RML6</accession>
    <name>A0AAV4RML6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Formin-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FNBP1</name>
        <name evidence="9" type="ORF">CEXT_163542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008060">
        <property type="protein sequence ID" value="GIY21849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RML6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11619">
        <property type="entry name" value="HR1_CIP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11911">
        <property type="entry name" value="SH3_CIP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000203">
        <property type="entry name" value="Cdc42-interacting protein 4, isoform F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057870">
        <property type="entry name" value="HR1_TOCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF12">
        <property type="entry name" value="CDC42-INTERACTING PROTEIN 4, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25610">
        <property type="entry name" value="HR1_TOCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="7">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="REM-1" evidence="8">
        <location>
            <begin position="261"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="426"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="338"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="351"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY21849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="490" mass="55513" checksum="FCE25198CBE732B2" modified="2024-11-27" version="1">MLNEVNDTAGQHEVIAETYCNQIQVEISDLVKEIKDERNGFFMRGKSTKVIYRIPDIVLISIKKTYEKSFKESEKANDTFVKIDADINLSRADVEKARLHAQLKNRTAEDYKTDYANQLQKTNELQRLHFYDLMPNIFQQLQDMDERRICCIQNVMQRFASVHKQVLPIILKCLDGIITAAEAINPREDTRLVIEKYKSGYDPPEDIPFEDLSNPRNGDVCNTLSSNRTDSLTVRGTMTVGKNKRRGILNIFSNNKEDFSDLPPNQRKKKLQQKIDEIKTKIQQETAARDGLMKMKGVYEKNPAMGDPATVEGQLADNGLKLEKLQNELLKFQGYMTDAEGNGNLSRDNRSSISEDSLSRSASDSSVCNPMNYKISAPNTPQQTHGSSNSPESGIGTSQPSITDDAENFPDPEFENEYEYNDEFDAVLGTGKALYPFTGQSEGSIGVVEGEEFDIVELDQGDGWTRIRKRNFEEGFVPTSYIETYLYNNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPM8</accession>
    <name>A0AAV4RPM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_435071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008271">
        <property type="protein sequence ID" value="GIY23410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="20300" checksum="94B5E166E4CAFCF4" modified="2024-11-27" version="1">MEKHRNRRRGQRSVVTWTARAFVRPGGNTGQRSLVAAGRANNGHQEYISPPSGTSVGLIWRSRWESCEREGVPPTSEVVRVSWSISHKLPRAGQSGVWELLLCAGVKSSVVRLTSNGVKGTFHSFPPSLSPSLGWDLSAETDATETSNFVREEGERTADIKVFLLPFVAREEKKIILKLGCNCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRI7</accession>
    <name>A0AAV4RRI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_708011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008259">
        <property type="protein sequence ID" value="GIY23289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10282" checksum="4575D6CA167B1DD9" modified="2024-11-27" version="1">MNFSHKSIEKFLNSKCPTISRNHDDKSQKKWPFLSINNLRVYSSASDKSESTADLRPLSSGARKCTSRKGWGWDGGEHLLPPRPQNISGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSG9</accession>
    <name>A0AAV4RSG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SET and MYND domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SMYD5</name>
        <name evidence="4" type="ORF">CEXT_295801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008349">
        <property type="protein sequence ID" value="GIY24089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402">
        <property type="entry name" value="SET AND MYND DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY24089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="32946" checksum="7838C5D0556D1EC9" modified="2024-11-27" version="1">MEDYLPRVEVRVIDDEKGKGLFALHKFNKGDMIFEERPLVCAQFLWNQAYGYLACDYCMRPLETAEENVRRLTGILDLVLPYPECCEIKKDDYIECPYCEFLLSRTSLGAISSSSLYIFFARKYSASFDQLQDAWREMHYPPETASIMLIARMIATVKQAKDKGGAAHLFSQFCHKTKSKNGDISHKLLGKQFQVQVEHLRQLIIKGLQDEDLLQWFTADGFRSLIALVGTNGQGIGTSAFGVWVKNCDSLDLSLEEQEKLNLYIHNLYERIESGNFPFSDLKVLMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXC5</accession>
    <name>A0AAV4RXC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_527441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008756">
        <property type="protein sequence ID" value="GIY26993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9773" checksum="8BBD91BCF78DB142" modified="2024-11-27" version="1">MQQSHWLLFRGKSEVTWILRNQNILYANFLLSRYAFTSISVAFIAFESQLQHASRSPPEWPEVYCADQIRVGITSKDMHDIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXY8</accession>
    <name>A0AAV4RXY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_193021</name>
        <name evidence="2" type="ORF">CEXT_193111</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008497">
        <property type="protein sequence ID" value="GIY25145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01008497">
        <property type="protein sequence ID" value="GIY25163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9980" checksum="5CCAD5B012AEE092" modified="2024-11-27" version="1">MPHPGKMAHATSKYNSFFPQNCCHRQLTLQRLNLQPGGALQPSFLVGRTNSGGKFFLRASQDRPDFNTFFWLLHSHITAVFSSHQHPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYU4</accession>
    <name>A0AAV4RYU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_30651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008767">
        <property type="protein sequence ID" value="GIY27073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="14741" checksum="BBDAA7BF6A12E770" modified="2024-11-27" version="1">MQGTEEVTYFNISHNRLTSLLQTCSNHGRSLKVRDSLPQPAAACRPALPHHPPQSHLSAIHAVSGFVLATDGMYCNSVNQCKPAALSLRLESAPGILVSQTGDLFENPRKTGEPSPSEFATIGFLFFSRKKWSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S617</accession>
    <name>A0AAV4S617_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_310891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008968">
        <property type="protein sequence ID" value="GIY28636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S617"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9999" checksum="D274C1D6B9B7059C" modified="2024-11-27" version="1">MCPFVGLRNKIKSDQVKYQLSYQQNALTDLDRPVNAFCQHQSPFCQRVRHLVTPNKGKGTSRKATLPTILPGKFLSSRTPDRTPKGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDK3</accession>
    <name>A0AAV4SDK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_440021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009231">
        <property type="protein sequence ID" value="GIY30477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="22073" checksum="871301A9BAAAB69B" modified="2024-11-27" version="1">MLENENNSAPFHSRALRNVMTVVHSPGNHSSTRGFIMFRIAFPSSGRCPLHPKQISEQEEPPWCSWKELRPWYQTMPWYAEEEEQCLHGMAASSMGENPPVLWEDYCSTCYYIPENYVREKGIRPPNMSEHSCTQGLRAFENMFSSPSIDSRTGSLSPLKARKHSEELGNLSLRRARNANALLHHHRKASEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHH2</accession>
    <name>A0AAV4SHH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_269595_1</name>
        <name evidence="1" type="ORF">CEXT_517981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009526">
        <property type="protein sequence ID" value="GIY32616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15227" checksum="874D35CF17F0CD1B" modified="2024-11-27" version="1">MPRWCDGGPPSCRMGVEAGGALGAEGACPSRSSLRGPLVSLGLLADPWEEIAIASCWPPTGEVLLLFGLPDDSGLLRSAARACALAVRRMRIDRFSLFHPSSPSPHTPLLFNPPVHPCSAGRGLRDLTRLATPFSFRSPLEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY23</accession>
    <name>A0AAV4SY23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_266261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010452">
        <property type="protein sequence ID" value="GIY39353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11868" checksum="235594C98531848C" modified="2024-11-27" version="1">METAENEWWRRMEREVTMDYSVRETALGASNPELMDTTCAAIPSERLASPIFPEKQSILSDEERCTRIFTVIKKKDIAQNLYDAYAATLTGYSPDDDDLKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T377</accession>
    <name>A0AAV4T377_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Afadin-and alpha-actinin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SSX2IP_1</name>
        <name evidence="10" type="ORF">CEXT_753001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ADIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010512">
        <property type="protein sequence ID" value="GIY39796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T377"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070161">
        <property type="term" value="C:anchoring junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034451">
        <property type="term" value="C:centriolar satellite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052300">
        <property type="entry name" value="Adhesion_Centrosome_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021622">
        <property type="entry name" value="Afadin/alpha-actinin-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46507">
        <property type="entry name" value="AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46507:SF4">
        <property type="entry name" value="SSX FAMILY MEMBER 2 INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11559">
        <property type="entry name" value="ADIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="73"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY39796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="523" mass="59775" checksum="2E37D0BA08DE2381" modified="2024-11-27" version="1">MENNFASEINDFCSSENIDECLKHISQELSALGYPSICSNSRTCQYAVNCDIVRLLNATFDLIRSYREHAHIKDELESRNHRLFSDLNALIKKNAQLKENLEQAENKQKSALEKERQVKEKNNRLLQAIKSEKEEMKKLSSQLLQQKNTYQHEIRKYENSINQLKAKLNQMIADKNPDKKSCQYISFKFTAEEFQTTREMENCMEEMYSSVISSYENRCQAMTKEILDYRQSLECIQQEVIATNSSLEGTSGDLLSLLPLSIYWNRNDLQKSLEGRFKFLLCRLKILVSLKRITLKMENNPEKGANEKKLSLCDKNVKDSKSSEETVSCRKVEEIEKEKADLELQKLETVKLALKQESPKIQWHENLNMVPSFSVVTTKEGLTAVPSAEDLKQCLNSPNQHVESLAPLWKNISLDSAKERKFRSELTVQNSQDISPLPSAIVEPPKDLAAESSHLPKWAIAAMASPTLSVISPEETSIHETSIITNTGEGQQELSNVSTTEQNLDLLKAVMEDIEKRRNQSPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGX8</accession>
    <name>A0AAV4TGX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_487551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011183">
        <property type="protein sequence ID" value="GIY44696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10044" checksum="79CE5A56C9184E7B" modified="2024-11-27" version="1">MNTIYSRNKIGNAYFELSLPLLYALTHSSHNVVRTYISHFGNNDLDVIGGIGLLDHQTYHALDVSALVIGSNWYIARKMTKPTICFTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGY0</accession>
    <name>A0AAV4TGY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein lifeguard 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GRINA</name>
        <name evidence="7" type="ORF">CEXT_430341</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011097">
        <property type="protein sequence ID" value="GIY44132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF47">
        <property type="entry name" value="TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY44132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="367" mass="40884" checksum="C6FD44629BC55551" modified="2024-11-27" version="1">METDDSKKEKKETKSQTNAADKKEEGTESFQSHLISAGSRYYSNATTTNLSSRNLSYATTTKYGATRNLSNAATTSRKPSNGQPFLVKDNKDSMPKQEPPQTNTIQEKDNQNNDFSRPSPPPEQQPQQNQAESGQVPQPQQIQGPNQTSQPQQYYNPQYIPSFSYAYSGRNYPPPLPYNQGVSHFNTTTVIHFGSYCTIHIRVFTLDLFVLKSKTLAASIMMGIMSSYDINTVLIAVGICASVCFAVTIFSFYTKFDFTSCGGILCILLLILVLFGIIAIFVRERAMTLIYAGLGSLVFMMYLAYDTQMLMGGKDDRNKSGRAYICGHTSLHRRHLHIHVSLNDGGRSSKQLTVGSNCFKTNELLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TLD8</accession>
    <name>A0AAV4TLD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_495721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011439">
        <property type="protein sequence ID" value="GIY46559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TLD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15402" checksum="463EA14E9C0B6035" modified="2024-11-27" version="1">MSHHFQLCSAFDPSTFNRSRILTGVESYVQVLWWTMTYGPVEGNERYPMRYTPLQVSLNATIFDEVYPIVPLDEMISDEAHSQSWFPFDEMISDEVCSQTIAWMQRYPMRHMPHHNPFLDAMVSDKAYSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TM83</accession>
    <name>A0AAV4TM83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_316731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011421">
        <property type="protein sequence ID" value="GIY46462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TM83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10544" checksum="E79F9B78393546E3" modified="2024-11-27" version="1">MHGDYPSDFLVGSFIEKERRPPLSSSTTASNSFWGLVMSCFAAADLIMMFREKMKVRVISCVLFVSRIVEFWSIYCLLCRNFLCPPSSQVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQ50</accession>
    <name>A0AAV4TQ50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_69231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011741">
        <property type="protein sequence ID" value="GIY48688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQ50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9167" checksum="741917AC73B38BC4" modified="2024-11-27" version="1">MSSRVNYINGGHHFDLCSVGIDRQQSAINSYLFAGEMAVVPESEMSGGWVNKIGYGGFVKHVRDSVSKIFYGCFCVFNCVDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS25</accession>
    <name>A0AAV4TS25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_705401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011829">
        <property type="protein sequence ID" value="GIY49408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20963" checksum="1E43E328505371F7" modified="2024-11-27" version="1">MFTNGLRVTSAVAHHALPGIHPHSHYRIWIINFDLKEKCVSFISLQPENFLELLLLRRLIREELTKILNKMDVHWKCGFTSATISLSIDWCYTEYLSTSGFRAVGLEPLYYTKGIHLNSSRRMTKMMLFECSIDTVYKWENRSSERPLNLDSERQMTYGSQFYGDNIIRSLLMTEIRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4E0</accession>
    <name>A0AAV4U4E0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_264631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012269">
        <property type="protein sequence ID" value="GIY52649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4E0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11753" checksum="5A8C0837D274F252" modified="2024-11-27" version="1">MKAHYYRNLFLICRALLKTFNEGNKGERKPQNTSPQVNVLCIFHHSTLAGVGGGFDVGKRKHLTRITLCRKAPFWKGCGQVRFAPCIYSGASQFYLNLEKEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7E3</accession>
    <name>A0AAV4U7E3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like-conjugating enzyme ATG3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atg3</name>
        <name evidence="10" type="ORF">CEXT_149281</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012397">
        <property type="protein sequence ID" value="GIY53742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044804">
        <property type="term" value="P:nucleophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY53742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14675" checksum="1537DDC89F8D327A" modified="2024-11-27" version="1">MQSVINNVKGRALNVAEFFTPVLKESKFKETGFVYAGDHLVHHYPTWQWAKGDEANLKPYLPPDKQFLVTRNVPCYKRCKEIENAEHHEELLEVDDEDGGWVDTHHYTDSAVAALADQVHEMTVQPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKG3</accession>
    <name>A0AAV4UKG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_698101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013044">
        <property type="protein sequence ID" value="GIY58263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9696" checksum="94E4F32FE5ED0E3E" modified="2024-11-27" version="1">MDEIMVDTLNNLPKTTFVKPVSLAIPYLISHSSRQLEMTVRNPQFHPHQTAHPPLFLQLQINHLCIAYPRPLMSMEGFTSTLPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULQ5</accession>
    <name>A0AAV4ULQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_800071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013095">
        <property type="protein sequence ID" value="GIY58731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8807" checksum="7EF7512AC97739A1" modified="2024-11-27" version="1">MRGNGSKENKPSQNGSYRKIDVHKKTYDRSKMRGNGSKENRHPQKSRHLQKIDVHRKTDDRPDTIEGRPIPARNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMY6</accession>
    <name>A0AAV4UMY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_771951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013153">
        <property type="protein sequence ID" value="GIY59086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9475" checksum="7DCC96DD589614BF" modified="2024-11-27" version="1">MQMSRKVGYRGDDDDDAVGYLPPLGGYLLHDGGDQLLFIDANCETETNRRPAVITHRLLSGQLQITVSISNSGRFFIGFHSLCSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4USK7</accession>
    <name>A0AAV4USK7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_454841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013416">
        <property type="protein sequence ID" value="GIY61012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4USK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11746" checksum="5C5C0245A1A7F7B1" modified="2024-11-27" version="1">MNSISGSICFAKCRLFGRRITQLGLSNFNPNTPPNKASLDRHHPIRRKKRNKKMTGRKTTHVSSLLTVGRQGRVAKDTVARYSLPETGWPSLVIYRPFVLLSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT79</accession>
    <name>A0AAV4UT79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_368091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013413">
        <property type="protein sequence ID" value="GIY61002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="38" mass="4575" checksum="53C50940F4EFEFC8" modified="2024-11-27" version="1" fragment="single">IHLISIVRRKIDKFVMSQDRIHFPPEKFQSLLKNRKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUN4</accession>
    <name>A0AAV4UUN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_517601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013478">
        <property type="protein sequence ID" value="GIY61527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15777" checksum="44381539A45910E3" modified="2024-11-27" version="1">MDHYQVHREVPENGTFFEGARQKSPSGCELIDFQLRELYKTLQMDIVNNERLVTVCLNTSNEPVRILIPFMILSSNCGYKSRCLKCGGGEHCFKECTKYPKTEKINQPNSISCGAIRQHAISEGAQDSLSPVLTLLRVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYA5</accession>
    <name>A0AAV4UYA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_583341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013660">
        <property type="protein sequence ID" value="GIY62743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="8866" checksum="E291B8E505B2464E" modified="2024-11-27" version="1">MPNTSKRTLMNGSPVTQTDPILPSATHSSLPPPHSNRGIGLNEKAQERYIMSSPPSVLSALSRQTLTSDSLSANQPLRPSAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V328</accession>
    <name>A0AAV4V328_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_764131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013904">
        <property type="protein sequence ID" value="GIY64641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V328"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10860" checksum="A07A178804FB1484" modified="2024-11-27" version="1">MPKELYLCYEVFSSLTSFSQCQRDPQGGRQTEKILKACTRQTICTMLVEERTVFLRQHRKMQYFGWWKRITKLSTCALITEMNVSSSTVHML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V346</accession>
    <name>A0AAV4V346_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_37791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013901">
        <property type="protein sequence ID" value="GIY64607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V346"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10936" checksum="9001E881E820B1A6" modified="2024-11-27" version="1">MLMKLICSRIYFASDADSSGETDRKKKAATGVCIAVREIHPKPLREQLGFFTVFAENLKKEKQSSKTKCSDLRRDGIRSENKQRRNYPEAIVAIASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V718</accession>
    <name>A0AAV4V718_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_300311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014001">
        <property type="protein sequence ID" value="GIY65523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V718"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11562" checksum="2A6B6D9A2E8312CA" modified="2024-11-27" version="1">MRVFSVFNNLDVGFQVNLEFDSLRIVETETWREEASFREVHSGGLCGQSFRCLFVCTIAKKSASFPCSGKEPPEQWTLGDDGSAQDASRFRDSRFRPTDCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7Y2</accession>
    <name>A0AAV4V7Y2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fatty acid synthase</fullName>
            <ecNumber evidence="5">1.1.1.100</ecNumber>
            <ecNumber evidence="2">1.3.1.39</ecNumber>
            <ecNumber evidence="6">2.3.1.41</ecNumber>
            <ecNumber evidence="4">2.3.1.85</ecNumber>
            <ecNumber evidence="3">3.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="69" type="primary">FASN</name>
        <name evidence="69" type="ORF">CEXT_234751</name>
    </gene>
    <organism evidence="69 70">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="69 70" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="32">Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="39">
            <text>(2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9627"/>
            <dbReference type="Rhea" id="RHEA-COMP:9628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78453"/>
            <dbReference type="ChEBI" id="CHEBI:78454"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="39">
            <dbReference type="Rhea" id="RHEA:41813"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="62">
            <text>(2E)-decenoyl-[ACP] + NADPH + H(+) = decanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41864"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="Rhea" id="RHEA-COMP:9640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
            <dbReference type="ChEBI" id="CHEBI:78468"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="62">
            <dbReference type="Rhea" id="RHEA:41865"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="46">
            <text>(2E)-dodecenoyl-[ACP] + NADPH + H(+) = dodecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9643"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="ChEBI" id="CHEBI:78472"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="46">
            <dbReference type="Rhea" id="RHEA:41881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="41">
            <text>(2E)-hexadecenoyl-[ACP] + NADPH + H(+) = hexadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41912"/>
            <dbReference type="Rhea" id="RHEA-COMP:9651"/>
            <dbReference type="Rhea" id="RHEA-COMP:9652"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78481"/>
            <dbReference type="ChEBI" id="CHEBI:78483"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="41">
            <dbReference type="Rhea" id="RHEA:41913"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="42">
            <text>(2E)-hexenoyl-[ACP] + NADPH + H(+) = hexanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41832"/>
            <dbReference type="Rhea" id="RHEA-COMP:9631"/>
            <dbReference type="Rhea" id="RHEA-COMP:9632"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78458"/>
            <dbReference type="ChEBI" id="CHEBI:78459"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="42">
            <dbReference type="Rhea" id="RHEA:41833"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="55">
            <text>(2E)-octadecenoyl-[ACP] + NADPH + H(+) = octadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41928"/>
            <dbReference type="Rhea" id="RHEA-COMP:9655"/>
            <dbReference type="Rhea" id="RHEA-COMP:9656"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78489"/>
            <dbReference type="ChEBI" id="CHEBI:78495"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="55">
            <dbReference type="Rhea" id="RHEA:41929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="48">
            <text>(2E)-octenoyl-[ACP] + NADPH + H(+) = octanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41848"/>
            <dbReference type="Rhea" id="RHEA-COMP:9635"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78462"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="48">
            <dbReference type="Rhea" id="RHEA:41849"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="57">
            <text>(2E)-tetradecenoyl-[ACP] + NADPH + H(+) = tetradecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41896"/>
            <dbReference type="Rhea" id="RHEA-COMP:9647"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78475"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="57">
            <dbReference type="Rhea" id="RHEA:41897"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="31">
            <text>(3R)-hydroxybutanoyl-[ACP] = (2E)-butenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41808"/>
            <dbReference type="Rhea" id="RHEA-COMP:9626"/>
            <dbReference type="Rhea" id="RHEA-COMP:9627"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78451"/>
            <dbReference type="ChEBI" id="CHEBI:78453"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="31">
            <dbReference type="Rhea" id="RHEA:41809"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>(3R)-hydroxydecanoyl-[ACP] = (2E)-decenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41860"/>
            <dbReference type="Rhea" id="RHEA-COMP:9638"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78466"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:41861"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>(3R)-hydroxydodecanoyl-[ACP] = (2E)-dodecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41876"/>
            <dbReference type="Rhea" id="RHEA-COMP:9642"/>
            <dbReference type="Rhea" id="RHEA-COMP:9643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78470"/>
            <dbReference type="ChEBI" id="CHEBI:78472"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:41877"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="30">
            <text>(3R)-hydroxyhexadecanoyl-[ACP] = (2E)-hexadecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41908"/>
            <dbReference type="Rhea" id="RHEA-COMP:9650"/>
            <dbReference type="Rhea" id="RHEA-COMP:9651"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78480"/>
            <dbReference type="ChEBI" id="CHEBI:78481"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="30">
            <dbReference type="Rhea" id="RHEA:41909"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(3R)-hydroxyhexanoyl-[ACP] = (2E)-hexenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41828"/>
            <dbReference type="Rhea" id="RHEA-COMP:9630"/>
            <dbReference type="Rhea" id="RHEA-COMP:9631"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78457"/>
            <dbReference type="ChEBI" id="CHEBI:78458"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:41829"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>(3R)-hydroxyoctadecanoyl-[ACP] = (2E)-octadecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41924"/>
            <dbReference type="Rhea" id="RHEA-COMP:9654"/>
            <dbReference type="Rhea" id="RHEA-COMP:9655"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78488"/>
            <dbReference type="ChEBI" id="CHEBI:78489"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="29">
            <dbReference type="Rhea" id="RHEA:41925"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>(3R)-hydroxyoctanoyl-[ACP] = (2E)-octenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41844"/>
            <dbReference type="Rhea" id="RHEA-COMP:9634"/>
            <dbReference type="Rhea" id="RHEA-COMP:9635"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78461"/>
            <dbReference type="ChEBI" id="CHEBI:78462"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:41845"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>(3R)-hydroxytetradecanoyl-[ACP] = (2E)-tetradecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41892"/>
            <dbReference type="Rhea" id="RHEA-COMP:9646"/>
            <dbReference type="Rhea" id="RHEA-COMP:9647"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78474"/>
            <dbReference type="ChEBI" id="CHEBI:78475"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="28">
            <dbReference type="Rhea" id="RHEA:41893"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="43">
            <text>3-oxobutanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxybutanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41804"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="Rhea" id="RHEA-COMP:9626"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="ChEBI" id="CHEBI:78451"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="43">
            <dbReference type="Rhea" id="RHEA:41805"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="37">
            <text>3-oxodecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41856"/>
            <dbReference type="Rhea" id="RHEA-COMP:9637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9638"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78464"/>
            <dbReference type="ChEBI" id="CHEBI:78466"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="37">
            <dbReference type="Rhea" id="RHEA:41857"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="58">
            <text>3-oxododecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydodecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41872"/>
            <dbReference type="Rhea" id="RHEA-COMP:9641"/>
            <dbReference type="Rhea" id="RHEA-COMP:9642"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78469"/>
            <dbReference type="ChEBI" id="CHEBI:78470"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="58">
            <dbReference type="Rhea" id="RHEA:41873"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="59">
            <text>3-oxohexadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9650"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78478"/>
            <dbReference type="ChEBI" id="CHEBI:78480"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="59">
            <dbReference type="Rhea" id="RHEA:41905"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="50">
            <text>3-oxohexanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41824"/>
            <dbReference type="Rhea" id="RHEA-COMP:9629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9630"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78456"/>
            <dbReference type="ChEBI" id="CHEBI:78457"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="50">
            <dbReference type="Rhea" id="RHEA:41825"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="34">
            <text>3-oxooctadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41920"/>
            <dbReference type="Rhea" id="RHEA-COMP:9653"/>
            <dbReference type="Rhea" id="RHEA-COMP:9654"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78487"/>
            <dbReference type="ChEBI" id="CHEBI:78488"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="34">
            <dbReference type="Rhea" id="RHEA:41921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="60">
            <text>3-oxooctanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41840"/>
            <dbReference type="Rhea" id="RHEA-COMP:9633"/>
            <dbReference type="Rhea" id="RHEA-COMP:9634"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78460"/>
            <dbReference type="ChEBI" id="CHEBI:78461"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="60">
            <dbReference type="Rhea" id="RHEA:41841"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="54">
            <text>3-oxotetradecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxytetradecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41888"/>
            <dbReference type="Rhea" id="RHEA-COMP:9645"/>
            <dbReference type="Rhea" id="RHEA-COMP:9646"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78473"/>
            <dbReference type="ChEBI" id="CHEBI:78474"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="54">
            <dbReference type="Rhea" id="RHEA:41889"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="36">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="36">
            <dbReference type="Rhea" id="RHEA:17399"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="27">
            <dbReference type="Rhea" id="RHEA:13098"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="51">
            <text>a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22564"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.39"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="51">
            <dbReference type="Rhea" id="RHEA:22566"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="49">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="49">
            <dbReference type="Rhea" id="RHEA:22837"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="33">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.85"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="44">
            <text>acetyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxobutanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41800"/>
            <dbReference type="Rhea" id="RHEA-COMP:9621"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78446"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="44">
            <dbReference type="Rhea" id="RHEA:41801"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="61">
            <text>butanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41820"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9628"/>
            <dbReference type="Rhea" id="RHEA-COMP:9629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78454"/>
            <dbReference type="ChEBI" id="CHEBI:78456"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="61">
            <dbReference type="Rhea" id="RHEA:41821"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="56">
            <text>decanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxododecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41868"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9641"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78468"/>
            <dbReference type="ChEBI" id="CHEBI:78469"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="56">
            <dbReference type="Rhea" id="RHEA:41869"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="40">
            <text>dodecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxotetradecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41884"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="Rhea" id="RHEA-COMP:9645"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78473"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="40">
            <dbReference type="Rhea" id="RHEA:41885"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="53">
            <text>hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:41932"/>
            <dbReference type="Rhea" id="RHEA-COMP:9652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78483"/>
            <dbReference type="EC" id="3.1.2.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="53">
            <dbReference type="Rhea" id="RHEA:41933"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="45">
            <text>hexadecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctadecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9653"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78483"/>
            <dbReference type="ChEBI" id="CHEBI:78487"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="45">
            <dbReference type="Rhea" id="RHEA:41917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="35">
            <text>hexanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9633"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78459"/>
            <dbReference type="ChEBI" id="CHEBI:78460"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="35">
            <dbReference type="Rhea" id="RHEA:41837"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="52">
            <text>holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA</text>
            <dbReference type="Rhea" id="RHEA:41788"/>
            <dbReference type="Rhea" id="RHEA-COMP:9621"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78446"/>
            <dbReference type="EC" id="2.3.1.38"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="52">
            <dbReference type="Rhea" id="RHEA:41789"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="63">
            <text>octanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxodecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41852"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78464"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="63">
            <dbReference type="Rhea" id="RHEA:41853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="47">
            <text>tetradecanoyl-[ACP] + H2O = tetradecanoate + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30123"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30807"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
            <dbReference type="EC" id="3.1.2.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="47">
            <dbReference type="Rhea" id="RHEA:30124"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="38">
            <text>tetradecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexadecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41900"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="Rhea" id="RHEA-COMP:9649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
            <dbReference type="ChEBI" id="CHEBI:78478"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="38">
            <dbReference type="Rhea" id="RHEA:41901"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="69">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="5"/>
    <dbReference type="EC" id="1.3.1.39" evidence="2"/>
    <dbReference type="EC" id="2.3.1.41" evidence="6"/>
    <dbReference type="EC" id="2.3.1.85" evidence="4"/>
    <dbReference type="EC" id="3.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01014084">
        <property type="protein sequence ID" value="GIY66143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004313">
        <property type="term" value="F:[acyl-carrier-protein] S-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141148">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016297">
        <property type="term" value="F:fatty acyl-[ACP] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08954">
        <property type="entry name" value="KR_1_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000015">
        <property type="entry name" value="Fatty acid synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049391">
        <property type="entry name" value="FAS_pseudo-KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF7">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21149">
        <property type="entry name" value="FAS_pseudo-KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="17" id="KW-0007">Acetylation</keyword>
    <keyword evidence="21" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="20" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="22" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="19" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="70" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0702">S-nitrosylation</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="67">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="68">
        <location>
            <begin position="687"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="66">
        <location>
            <begin position="1963"/>
            <end position="2045"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="64">
        <location>
            <begin position="687"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="64">
        <location>
            <begin position="826"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="65">
        <location>
            <begin position="2037"/>
            <end position="2061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="65">
        <location>
            <begin position="2037"/>
            <end position="2054"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="64">
        <location>
            <position position="724"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="64">
        <location>
            <position position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00023373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00023388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00023394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00023398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00023399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00023401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00023402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00023442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="ARBA" id="ARBA00044883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="ARBA" id="ARBA00047300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="35">
        <source>
            <dbReference type="ARBA" id="ARBA00047394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="36">
        <source>
            <dbReference type="ARBA" id="ARBA00047400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="37">
        <source>
            <dbReference type="ARBA" id="ARBA00047440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="38">
        <source>
            <dbReference type="ARBA" id="ARBA00047451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="39">
        <source>
            <dbReference type="ARBA" id="ARBA00047500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="40">
        <source>
            <dbReference type="ARBA" id="ARBA00047578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="41">
        <source>
            <dbReference type="ARBA" id="ARBA00047810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="42">
        <source>
            <dbReference type="ARBA" id="ARBA00047897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="43">
        <source>
            <dbReference type="ARBA" id="ARBA00047953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="44">
        <source>
            <dbReference type="ARBA" id="ARBA00047961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="45">
        <source>
            <dbReference type="ARBA" id="ARBA00048051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="46">
        <source>
            <dbReference type="ARBA" id="ARBA00048281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="47">
        <source>
            <dbReference type="ARBA" id="ARBA00048289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="48">
        <source>
            <dbReference type="ARBA" id="ARBA00048420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="49">
        <source>
            <dbReference type="ARBA" id="ARBA00048506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="50">
        <source>
            <dbReference type="ARBA" id="ARBA00048571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="51">
        <source>
            <dbReference type="ARBA" id="ARBA00048650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="52">
        <source>
            <dbReference type="ARBA" id="ARBA00048691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="53">
        <source>
            <dbReference type="ARBA" id="ARBA00048704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="54">
        <source>
            <dbReference type="ARBA" id="ARBA00048935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="55">
        <source>
            <dbReference type="ARBA" id="ARBA00049019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="56">
        <source>
            <dbReference type="ARBA" id="ARBA00049109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="57">
        <source>
            <dbReference type="ARBA" id="ARBA00049171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="58">
        <source>
            <dbReference type="ARBA" id="ARBA00049263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="59">
        <source>
            <dbReference type="ARBA" id="ARBA00049414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="60">
        <source>
            <dbReference type="ARBA" id="ARBA00049422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="61">
        <source>
            <dbReference type="ARBA" id="ARBA00049449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="62">
        <source>
            <dbReference type="ARBA" id="ARBA00049521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="63">
        <source>
            <dbReference type="ARBA" id="ARBA00049533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="64">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="65">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="66">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="67">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="68">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="69">
        <source>
            <dbReference type="EMBL" id="GIY66143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="70">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="2248" mass="248545" checksum="B04927A2B49D2DB1" modified="2024-11-27" version="1">MDTSCSSGALAFYGNSSSFHSFRHQCGSYCWKGAFNLCLRPGTALQFYRLNMLSDDGVCKSFDAAGNGYGRSEAIVTLLLQKSDVARRKYASVVHIKTNTDGFKEQGVTFPSAAMQKRLIKEVYDECKLNPLKISYVEAHGTGTPAGDPIEMSAISDIFCAGREEPLLVGSVKSNMGHSEPTSGLCSVVKVIIGMEKGLIPPNLHFYRPNPSIPALVDGHVRIVTNPTPWEGGYAAVSCFGFGGVNVHAVLKSNTIDGKQKEVENIVIPQLALYNGRTEESVQYLFDYLQSENPPRDFFALLHKSIYSSTAGKPYRGYKLLVKDQEVAEIKKVVSDDRPVWFIFSGMGTQWPCMAKQLMNMEVFANSIKRSAEVLKPYELDLIDLVTNGVKNEVNSRSIIPAFVSIAAVQVALVDVLNEIGIKPDGIIGHSVGELGCAYADGSFTAEQMVLAAYWRGKAVEEANLETGAMAALGITWSQANKCCPKDIFPSCHNAEDSVTISGPKDSVKVFVDALKAENVFAREVDSCGYAFHSQYIFPAAGKLQSALEKVIPNPKPRTSRWVSSSYPKDQWDEPHAKLAGASYFVHNLVSPVLFHEALHHVPKNAIVVEIAPHHLLQAILKRVIGPDAEYIGLMKRNVDNTVHLLSSLGRLYSAGLNPDIEKLYPKVQFPVAKSTPMISPLIKWDHSESWTVAKWDKNTNQSQMITEVNVGSEESPDKYILGHCIDGRCLYPATGYLLLVWKALAELKGKDLSAFPITFEDVKIHRATVLSKAATTKFLVDITNAGGEFEISEGGMTVCTGHVYSPETTKNNDLSPSIKSDDIKSLPLNQNDIYKELKLRGYDYGPTFQGVSGSDIEGNTGLLKWTGEWVVFLDTLLQFTILGSPKRALCLPTRIQSIKIDPAFHKTYMESSLKEYQGVPVFHDKNTKRIISGGVELKNLKASFAPRNQGKQIPLLEEYRFIPYNEANILSQSDEETLERYIHVCSSVAKMILELSGKSKEQISDVMNGFKEADDALIASYLKSYTDNHVLLKSLCGIMNTATSKDLTRHVKNYVNNYLLERDNDILSQTMLREDPLRAVLDVVLENSISRKLKIAEVADTAIPLSAKISEFIQTLGILNVNYLIAHSKSDNMDKSSLSSANFELTSWDPKTALSFKDVDLFVMKFLNYPTKEYSHILENAMATLKDNGFIIVLQRTHLVPAEMFLSAVGETVLPIYTESDLEQTFKDLKLQVVCKKSDSLTSTLYLLRKTPDLSYEDIIIPIVEDSYEKWVNELSEKITSAQGSAGSKRIWLVSEATNNTGIIGLVNCLRQEPGGSSIRCVFTSKGSPKLPDFSLKNQFYQEVLEKNLTMNVFKRGSWGSFRHLTMPDDHGKVVTNHAYLNVLTRGDLSSLVWVDSPLKYFKQPTDSVLCQVYYAPLNFRDVMLASGKLPPDAIPGDLALQDCILGLEFSGRIESGQRVMGLVPAKGLATTVAADPNFVWDVPDDWSLEEASTVPVAYSTAYYALIIRGNLKKGERVLIHSGSGGVGQAAIAIALSLGCEVYTTVGSSEKREFLKKRFSGLEDKNFCNSRDTSFEQYILNVTGGEGVDVILNSLADEKLKASLNCLAQHGRFLEIGKYDLSNNSPLGMAIFLKNISFHGILLDALFESKNYSSRVKKEVVQLVKDGIANGTVKPLNSILFDHEQAEQAFRFMASGKHIGKVVLKIKDEESQKKIVPTPVQFKALSRTTCNPEKSYIIIGGLGGFGLELCQWLVERGAKNIILTSRSGVKTGYQKLCVNRWKQDSINIVVSKLNVTKLDETKSLLKMAEAIKPVGAIFNLALVLRDAFMENQTVQNFKEVCESKVTSTLNLDVASRELCPELEWFVCYSSVSCGRGNAGQSNYGYANSVMERICEERCKEGLPGLAIQWGAIGDVGIIQDTVGSDVVIGGTVPQRINSCLTVLDKFLQQNHPVVSSFVPYQPSETTTQKASKHNVLSTVSKDMSSINPETSLGELGMDSLMGVEVKQFLERDFDLVLAIPELRQLKVKDLKELEGSNEEIKPASKSETKKELVSEQTPESDSKIVEKIPEHFSALPSKQLVPDNTIIHMNSIKNGIPLFIIHPIEGTVAMLNSLAQLINFPVYGIQCTPEAPSESIEQLAAWYWKNIKTVNLSSTIYLAGYSFGGSVAFDMCLQAERNPHDHAKVRNLVMLDGSPALVTAYTREHKSHFKGDSTEEEAQALCSFVMQFIDISMRQLKNRTNEFENSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCS8</accession>
    <name>A0AAV4VCS8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HAP1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_208107_1</name>
        <name evidence="3" type="ORF">CEXT_249141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014284">
        <property type="protein sequence ID" value="GIY67813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051149">
        <property type="entry name" value="Spindly/BICDR_Dynein_Adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32123:SF13">
        <property type="entry name" value="BICAUDAL D-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32123">
        <property type="entry name" value="BICD FAMILY-LIKE CARGO ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY67813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8934" checksum="76394ABD4AD7FF7A" modified="2024-11-27" version="1">MQQHNFYGDLEDYVCQMEKQQAQSAADADDVFAQLARKEKDLILAAELGKALLEKNEEISRANERLTEEYSQQLEVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFE0</accession>
    <name>A0AAV4VFE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_593731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014367">
        <property type="protein sequence ID" value="GIY68359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="23766" checksum="DBF43D503B384496" modified="2024-11-27" version="1">MKLEILVKGRNLIDSPIGNVRFEKSDNDSEFSRRDGEGKQSADLTAASAILAGLVLLRGETVKSKRFIEDVTEGGAAPAFRKQSQRIEKHLQSKATSQLCGTLPQEIVGEELRVGSIDKRTYVVGMELNGVFPSQVLPLDLTFVRVGVIHMTAEWGRSLGAQVTPRTQQRTARARAPRRAMGVGAMEVLESSSSERRWKIGGRAASGWSTPFERMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJR0</accession>
    <name>A0AAV4VJR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_582541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014582">
        <property type="protein sequence ID" value="GIY69768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="15718" checksum="8D6F05FE712397ED" modified="2024-11-27" version="1">MQTIYIMKTVTENPFGLVNADEDAVFSIKRFHDPPQLEPLTHGGSKKESAKEAKKSDKKPSSWPRGADIAVRPDTADLRRYNNHQGGGPGREVPPCLGLITRQVSCSLPSLLPPTNLYIKKLSLNDVPDHQVSDHSKDASRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTR6</accession>
    <name>A0AAV4VTR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_569831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015122">
        <property type="protein sequence ID" value="GIY73795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11393" checksum="C344E114B9FB62D5" modified="2024-11-27" version="1">MLQVSPRKELWTIRGLCPRGTATGWVCVCGRSCLLGNSERMTSQTCLESLRGQPTGLGCSLAQSLGHNASNASQMYDQIIMSSDHVKDSCSPRRSPMFRVEVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWR0</accession>
    <name>A0AAV4VWR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_746041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015222">
        <property type="protein sequence ID" value="GIY74458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9883" checksum="BD64F8E03C7110DB" modified="2024-11-27" version="1">MHFTTTFMHVRCIHYFKTRSFLEPSPLLRIQEPLSMHLPHSPNNTIFSRLTVNNTSAFTAMQFLRSSESCLRVREISPPHIRAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4J0</accession>
    <name>A0AAV4W4J0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_629101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015535">
        <property type="protein sequence ID" value="GIY76799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4J0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10358" checksum="5C41B8D722AC1039" modified="2024-11-27" version="1">MLLTWVYSPRCGCRVVKGQDHIQIGIICQIPRVSLLNTWMKKLSCFYADGEVFRHTRPPYLISSPRWCDGLTLPRRQLKGNALKALSQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6U6</accession>
    <name>A0AAV4W6U6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane channel-like protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tmc5</name>
        <name evidence="9" type="ORF">CEXT_545641</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015659">
        <property type="protein sequence ID" value="GIY77671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038900">
        <property type="entry name" value="TMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012496">
        <property type="entry name" value="TMC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23302:SF43">
        <property type="entry name" value="TMC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23302">
        <property type="entry name" value="TRANSMEMBRANE CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07810">
        <property type="entry name" value="TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="TMC" evidence="8">
        <location>
            <begin position="69"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY77671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="369" mass="42725" checksum="18AF1CB5176DABDC" modified="2024-11-27" version="1">MTLPLTVTCIGIISYFVLKHATRLELYLSNRLRLYLTMIRVVTLRIVMLGIIAYFWIFIHKPPRDDNICYETELGKEIYRLILVNFLVETVVFTLIGEYGRKLISLCFPAIGRSTFDVAYNTLDLIYYQTLAWIAMFCVPLGSLMILIILIILFYMKRISMSVTCKPPVRSWSVNEAQTFYLVLTFIMFFFAALTVGYSIFGLVVYYIRAQARAHISVIKKIREQLILASKDKVFLLKLFDEAFIEHWRNKGVLNTKSKDKETPRRMSDNSQHDVFNEGYTEYYDRPLESPLHQKFSPNYIPAKVPINMINHDNGSPSHNNINNISGRSDGFRSPIASFSKESPLQLRRGSPYPSHQHGFRHLISEDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7S2</accession>
    <name>A0AAV4W7S2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_396251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015822">
        <property type="protein sequence ID" value="GIY78940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7S2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="32" mass="3637" checksum="BB797BF984B9F5C4" modified="2024-11-27" version="1" fragment="single">ADNNHLQFQVWSTRDAISQGDEHPRGGDNRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7W8</accession>
    <name>A0AAV4W7W8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_100721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015709">
        <property type="protein sequence ID" value="GIY78031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7W8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12075" checksum="CA9912703B6D0EE4" modified="2024-11-27" version="1">MHIRIKSQHLIRTNTCYRRSCNGHPLLNQPSERVQHGPLKLLLQERARISSKPAPHTSSAHLVQKLLCLHKSNFSCYFCKRIRRGLYVHPRGGGGRGVPRRFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBP6</accession>
    <name>A0AAV4WBP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_618441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015986">
        <property type="protein sequence ID" value="GIY80232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8842" checksum="AEAC8D629F0D9F5C" modified="2024-11-27" version="1">MESASLLSASSHFLTEEGYIKLAEWRFIHKGKFYLVPQNGAELCKRSNNEGYRRCTESRENPTILDVLPHGIPKMTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEL9</accession>
    <name>A0AAV4WEL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_597471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016099">
        <property type="protein sequence ID" value="GIY81237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12608" checksum="E6D7FC5C77921E09" modified="2024-11-27" version="1">MLLIDVIKKDKVTKIESLPFRNFKAYFKRIQKERIFQKNSKTKITQKRTARSHLAFPKVLAKRSLFHQERLLTPSLSYQTATYCEDACNNLKPESLQQKSPDHPCSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WR82</accession>
    <name>A0AAV4WR82_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_629751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016513">
        <property type="protein sequence ID" value="GIY84440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WR82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9399" checksum="DA6B328780809FEA" modified="2024-11-27" version="1">MHFKLPLTQLSWKRRLHEATPERWCRNQAVHRQFHSNGVESSWLLFGENELFPLSETHKRTGNNGNLFMRRQSSGPAVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRC5</accession>
    <name>A0AAV4WRC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_08449</name>
        <name evidence="2" type="ORF">CEXT_390841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016576">
        <property type="protein sequence ID" value="GIY84834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043719322" evidence="1">
        <location>
            <begin position="23"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="580" mass="64994" checksum="9EE1C3F1ED2E208C" modified="2024-11-27" version="1">MFTMNAGTAFIAFFAFLPIASPFMNVGDFSRNGLKRCYERGTIPEKVNGQDLPLPSSIETFISLIERYETRQPSVTTTDLIRKLLMSFKVDDLSGDFRAWTSSARYANDFETYFFNVVSRPKYEFETGDFTDDEKCALHFMLSHTINGTAWGNEELLEDGTVKHPREYGVVSVHSKWKHAFSLSKVLLGIQAGLLGNNERSANEVIRSLQSGQGDENLGSVKVNRLYAVTLGTLVSHYANKIYKRNEPITFVPNGMWNDASCPTYYVLNENNNKYVTNSVIRGAIDGLIIGLKISDKPETFQKMKLSQILRMYYGPTGLIDETDSGSRSNYQWCERERNFDNLRNVPDEVYKFYLLYTSYLGAEPVERAQEEVNEIINSIQKSSEVFNDILAEASSECLRSDTSLDKRCSTPSDIFAILDWGTEVQRNFQIEIVGNLSVNFDIGPKGSSVAVYSNMKSQLSKGLNTIINNTGVSGCQSCFAKYYQRGGGKNSDIEVIEKLNETLADFVEHYDKAQSEFNTVKSGTPAKEATILGIGPGKESLKVFTLKDDHDIFQIPTGSANALDFASKLRSRICKVSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1K8</accession>
    <name>A0AAV4X1K8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_801871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017061">
        <property type="protein sequence ID" value="GIY88403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1K8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008164">
        <property type="entry name" value="XGLTT_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01744">
        <property type="entry name" value="GLTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="279" mass="27520" checksum="2ECB554A6EB64FF0" modified="2024-11-27" version="1">MSTCERKLDANAIIDVCKGRYLLCCIGSFHASLVGPLGLGAPVLAAGPLGLGLGKGLIAAPAVATVSSQRTAINHVAPAAPIGAAAPIALANGIVANGLIANGLVGNGLIANGLVGNGLIANGLIGNGLIANRVIGNGILGNGVIAGNGILANGLVAGHGIAGAPLAIGTGLLGAPVGLGVGKLGLGLAGPLGLGLGKAILDLRKSVVLNVVSNKCPKCCKDTLIHWCQWHRMWKEFIRALPIPAPRIPAPYPKPRAAPCPITPPYATGAAMAPIPIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDS9</accession>
    <name>A0AAV4XDS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-tocopherol transfer protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TTPAL_5</name>
        <name evidence="2" type="ORF">CEXT_682901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017500">
        <property type="protein sequence ID" value="GIY92116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="51"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="235" mass="27389" checksum="551F8301D0DCE42A" modified="2024-11-27" version="1">MDGYGELSACLYLYLRRNKYDVKKSFKHIQNLISLRKKQANIFESIPDEYFSTKISTHYIAVLPKRCAEGCTIIVSKLGLWNTDELSFEDFKRIIVFTFLQLFRDPMNQINGFKFIHDFSGTSIHHLKYCTPQALHLLYHSSLYCIPGRYKEIHLLYDSIALKAVWAVARLMVSEKIKQRIFIHSSPEELHDYFPRSALPAEYGGEIENIYSEDFARKANKANTEYTLAGQANFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGH7</accession>
    <name>A0AAV4XGH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_224691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017672">
        <property type="protein sequence ID" value="GIY93518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10920" checksum="21C8D2E65B792357" modified="2024-11-27" version="1">MRQSVGRRQSWIKGGLSTSKATFYGAGTQLRKRALSPPFRLLGWDSRISPWSFKSHFLDFLAHVRLSFGFYDEGKRESGIFVHDSYFLLTKEWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK28</accession>
    <name>A0AAV4XK28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transient receptor potential cation channel subfamily M member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Trpm1</name>
        <name evidence="2" type="ORF">CEXT_602651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000522">
        <property type="protein sequence ID" value="GIY95440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005261">
        <property type="term" value="F:monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050927">
        <property type="entry name" value="TRPM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13800:SF1">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL TRPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13800">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="359" mass="42375" checksum="69272DBC7F384F5F" modified="2024-11-27" version="1">MVTWIFWNKLDVVWILFFFVGVTVRLTSYFVYISNWVKLDDVHLIYTFSCILSYIRLYEFYMTMSHIGPKLIVLKRMIGDLIVFFLIVAVCILCYGIGRVALLHRERQPFWNVFTEIFSLPYWHLFGELDLDEDSAGRFPSCDEDPTYCHQSPHAWIVPIMLAIYMLIEIYCWLTCSLLYSRKHVFDEVNANSREIYLFEIYVSGQQFSRRSILPPPFLIVEDLLSGTYFLCMKLYHKIYSKCCCCIQGLNEKCQMQKKLRLIYVGNLRLFEKEGRAKISYLKDFVKKLNLLHNPKQTPKSEKHSKYKESAISKAKMQFFASPGDKKNEEDEDLRSQLDVDDFILQWSTIKKGVLPSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNP9</accession>
    <name>A0AAV4XNP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_602601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000522">
        <property type="protein sequence ID" value="GIY95434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13445" checksum="A13A807B8442A265" modified="2024-11-27" version="1">MTQYVYIPKRHRLNTSREKRRQQTADISHRCDAAFEFELHVWKEATAVVVSKVLGKKSHCRKGEIVDFVSLKYGQCLILQGTSQSFETFTPLSRRMSRVPTARQLSFKWLKVDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQR4</accession>
    <name>A0AAV4XQR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_351511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000694">
        <property type="protein sequence ID" value="GIY96713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10975" checksum="BC28CDD7E2916BDC" modified="2024-11-27" version="1">MDSKTAFKDHTPKRKTVPITANPSKKKIVVYDTILAHNCNLLPLMNKIQKLLGDCAPHNASPNKESQKSGTANLRACEDLLSINCRVEYLTNENLIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XS63</accession>
    <name>A0AAV4XS63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_622951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000868">
        <property type="protein sequence ID" value="GIY98001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XS63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11772" checksum="DEBA53CBFA35EF8B" modified="2024-11-27" version="1">MHCQSAQYIKIAKFHRQTPPDSQKCSNPGILISGLSEQAGIGSRKVEKRSCNPSIISTIIPKCCLLEQCYQMSRVPGKKSPRKRKIRTFPMGTENWGDASSRYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXZ3</accession>
    <name>A0AAV4XXZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001088">
        <property type="protein sequence ID" value="GIY99837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8553" checksum="04A16E43B0E73F6D" modified="2024-11-27" version="1">MMTATVLRRDNGSEMRQGCGALPGRDCPWKKCSMSGGVEGRGKAINETDSIAFRKKERPIEQLDWIQIPFWLNWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZA1</accession>
    <name>A0AAV4XZA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rho-related BTB domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RHOBTB1</name>
        <name evidence="3" type="ORF">CEXT_207042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001022">
        <property type="protein sequence ID" value="GIY99214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY99214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="19236" checksum="56017F09BBF3025E" modified="2024-11-27" version="1">MDNEQPHQEHVKCVVVGDTAVGKTRLICARACNARLTLNQLLTTHIPTVWAIDQYRIYKEVLERSYRRFAYGRSDVVLLCFSIANPMSLRNCKVVWYPEIRRFCPSTPIVLVGCKNDLRYMYRDEQFLSLCRDRSPFFRPLRESDILSPEQGEICCKRNWSTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6M9</accession>
    <name>A0AAV4Y6M9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_237531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001350">
        <property type="protein sequence ID" value="GIZ01792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18564" checksum="04E7D38859AFCB3B" modified="2024-11-27" version="1">MRQDTKCTQDFISTRSRILPPRVGSPNFRPISASHLSAFLEHTSLDCLSGRHRIERMFRTGFRNTGVSFEQDKVQIPRPTSASSLECVLNTGLNRLSDDLEPEWTARSGFRTYCRKFCHHVSGVQIPVPHRLFLNAGLDYLSGRHGMKKKARFGFRNTLVYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE96</accession>
    <name>A0AAV4YE96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_92871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019307">
        <property type="protein sequence ID" value="GIZ05385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="19424" checksum="50F1E4B6C41384EE" modified="2024-11-27" version="1">MLWSIISFLTRLWNDYIKQILFERIYYSEIKWKDNQSIPQVVNRCLDSYQSSEEPNLVPFYIDANDEHFQNYGFDYISDSLLNSDETSLFSTKESSEMGTFNKKILGTRTDLRHRVTTAAEMKNHPLTKSSNGLISEGVCKETDENETMSQKHSPNVEYRKSKIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YG54</accession>
    <name>A0AAV4YG54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_31691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019228">
        <property type="protein sequence ID" value="GIZ05167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YG54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17208" checksum="0FA1860F375EE8A4" modified="2024-11-27" version="1">MDKAGKIPYRKLLAKRSPEQFRVPGCGHNFECREGSLFPLRLGKPSSGFCFPLFFKSEDTGYTMYRCCNAWYHNNIWSQSIGHYLECRELSLGKLSLDIYSVFCSPFLEFGRTSHVPCIVAVMPATESYYDTSLLYEWYEPKMLLAILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YG85</accession>
    <name>A0AAV4YG85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Structural maintenance of chromosomes protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SMC4</name>
        <name evidence="7" type="ORF">CEXT_43201</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019267">
        <property type="protein sequence ID" value="GIZ05289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YG85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF172">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043652210" evidence="5">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="6">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ05289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12302" checksum="DCC899CCB19BF8FF" modified="2024-11-27" version="1">MSCCSVISLFEFIVRLRTSCIVGPNGSGKSNVIDALLFVFGYRAQKIRSKKVSVLIHKSDQYPDLESCSVTVRFATIKDELFAELYTKERNLLFECILSVVLLGKLWGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M612</accession>
    <name>A0AAV4M612_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_438821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019407">
        <property type="protein sequence ID" value="GIX67506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M612"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10534" checksum="D5924D974F51630C" modified="2024-11-27" version="1">MSKVCERQDHKRMNKTLVYETCQEVDFTEALSYDPPKKHYKQNFFHKIWLNVQAGQFWGINRETSGICCTLGKFDYQPLEVPSPELFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAC5</accession>
    <name>A0AAV4MAC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_97381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001992">
        <property type="protein sequence ID" value="GIX68712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8210" checksum="B973B1F2F069EACD" modified="2024-11-27" version="1">MLLLHCGAACEIQVQRGSKFGRGGENRTLQNPPAASDWTIVASPASDSSTWRRAKITDSCRVFGYLQSRGIQLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDN3</accession>
    <name>A0AAV4MDN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Sms</name>
        <name evidence="5" type="ORF">CEXT_538461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019683">
        <property type="protein sequence ID" value="GIX70524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016768">
        <property type="term" value="F:spermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000197">
        <property type="entry name" value="spermine synthase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015576">
        <property type="entry name" value="Spermine_synthase_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315:SF1">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="71"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX70524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="353" mass="39743" checksum="4DCD7B93EB3E67C6" modified="2024-11-27" version="1">MVCFSNEDGSLTCSFKTYPFGLATLTFEDSYDEDTAFTNPVKIEEIRKELHRNFKVKVEKIPIIKRGSPVPLYFTTADERILEYDFNKVVFQDESPYQNIKILYSPTLGNCLILDDLQNLAESDINYTHGVMKHGSVSYAGKEVLILGGGDGESLINSYIDQMVIDACRMHLRGCCGDSLDKLEGPNYKVIIDDCFKKMDEYKAAGKTFDVIINDLTDIPIATSPQGEMWDFVRKIINKSLAILRNDGSYLNHALGESCVESLKTYENLLSALPVKVSFERHSAYVPSFMENWVFYEIKKGEKLQTYFAHSTQGQPLTTIRQPTRTLRGASLDHVLDCLGSPNRSIITTSSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGJ7</accession>
    <name>A0AAV4MGJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_746481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019707">
        <property type="protein sequence ID" value="GIX70970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8654" checksum="BFE18CDF03397080" modified="2024-11-27" version="1">MARAKREGSEVHASTRKDSLEKGWGTCILYGFKRRRKPRIRVIDIPLREEEERTCFHDSISSLCDSTNRVFTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLJ3</accession>
    <name>A0AAV4MLJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_187831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002405">
        <property type="protein sequence ID" value="GIX73387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="29992" checksum="38376EE6A5D506AD" modified="2024-11-27" version="1">MPLEIAKNQSQQESNYRGNNTEIDHQNRMVDSFNLPNTNILASIEAQGSEGSQQTVDILAGVDDGVPKSRDGSLAVKQIPTTVRTTVTDCRQITKCYEVEEDVSRSHDPSEDEVESKFFGSQEVLPGRDTLGQRDDEQRHESVEGQLARVQILHVLDQHGHDGVEDSGQHSQEEALEEEEPARRQDFILVGLDGFSAMGLQLKSLASAGHLVGWMEKELPRTIEINPLKRNQNLPMNLPSRTKYIIKKKKKKKNLQPQHERLVPTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMP1</accession>
    <name>A0AAV4MMP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_220161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019924">
        <property type="protein sequence ID" value="GIX73170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17775" checksum="D6B8D68D827BB965" modified="2024-11-27" version="1">MCGIMQRAVEGLLIGHQRWTLVRREPQFIFVSKLERAKPQFGNPTASRSHFYVEFLVQEEKEKYDHYLSYAGGLWVFVVVGTSTPGCGCGYFSFYYGSNYAPGRLWLWVLLLLRYYGGTSTLGNGLEYFKSGLICQNKGNGKENKMVRRWWMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSS0</accession>
    <name>A0AAV4MSS0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_275141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020162">
        <property type="protein sequence ID" value="GIX75353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043887335" description="Cytochrome P450" evidence="1">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13364" checksum="328480FAD18CB8A0" modified="2024-11-27" version="1">MLLYIALVVVVLFCVRLLLDKQSRVCHLKRLPGLKPQFLIGNIGWILNIYTRKSEYHPSVYILERVLGHNVLFEKHGFHCFWIGSSPIVSVFSPHLLEVSFGLLNAPEHAENKRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MT72</accession>
    <name>A0AAV4MT72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_436131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020023">
        <property type="protein sequence ID" value="GIX74084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MT72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10497" checksum="860298035ACB841C" modified="2024-11-27" version="1">MKLEVYPKHEFLMHLSPVNREEPHSPSIYILTTRLRHHTSKEASPNEPGIKSVAALQRVVAINFPTCKQASPGASQLQARPPFATRERERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2V5</accession>
    <name>A0AAV4N2V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_622651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020462">
        <property type="protein sequence ID" value="GIX79052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="21438" checksum="273187B4CCD00511" modified="2024-11-27" version="1">MCWAFHSSSDLGMGFQANVNTPTFACFWVGSGALQTAPHIGRQTGGKMQVPHWATTPICSWASADSGHGISGRDSHLLTPEHGLPGSLTTDTALTLGMGANQASLTFLLWACFQANGHIGTYFSLHPCFLSMNRTNTLGTLHLLFPEHGEFPESRNIHWSLPPHRLEREFQTASQGMSFQANIHIEPLRNELRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N505</accession>
    <name>A0AAV4N505_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_43291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002984">
        <property type="protein sequence ID" value="GIX79912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N505"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="18317" checksum="F0C8B195142FCA32" modified="2024-11-27" version="1">MFAKAVSAYAPLVNTGVSAVSNQQDAYGNYAYRYDIKDAATGSLNSKAEVGKVGIATIAAPVAYGAIAAPAIGYGGALGLGYGAGALGLGYGAGVLGAGYGAGVLGAGHGVGILGAGYGAGVLGAVITYGDCAAPAIAAPIAYGGYAAPALAARVAYGGFAALLAYGGALGLGYGGALGLRYGAGILGAGLGNAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7Q4</accession>
    <name>A0AAV4N7Q4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_365481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020604">
        <property type="protein sequence ID" value="GIX80551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31569" checksum="67FABF88511BE83A" modified="2024-11-27" version="1">MAGIMTSVPEKRYLPVNLENEANETVKLAQKKPCCMQAHEKIENCTLARKENGTSEIITTPPEMSTNQNNCDDLDPFLKLLAEMDDPKNATKPYVQYIKSLSTKYPGILMTSETGKQSSSNEDARSLEPDIKSQAKPTNEKGITEILELDVKPHAKSTNEKGITEILELDVKPHAKSTNEKGITESLELDVKFHAKSTNVESTTESLELGAKPRIKLTNGKETDANPVDIFGNCFTTKERNKITVACPHCQKKVRALGFISHLSYCMGVGIRKRTRNSYKNFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBR4</accession>
    <name>A0AAV4NBR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_328301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003212">
        <property type="protein sequence ID" value="GIX82157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8567" checksum="345CDC355F2A1476" modified="2024-11-27" version="1">MSENHSAFKNKSTKRVSNQRVDEMLLNLKQQLCSNSTLPRMLQVEPDAIKLKCFSNDWKHTLQRHHLETSSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBZ8</accession>
    <name>A0AAV4NBZ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_374811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020750">
        <property type="protein sequence ID" value="GIX82141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="9226" checksum="2733596906A9E1C3" modified="2024-11-27" version="1">MFAAEEELIILSIKRRLCDLEKSTRFDIEYEKSTFDPPLRICPKCGRKTKYSLLKPMKTKRQFLNESLTFYRESMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE25</accession>
    <name>A0AAV4NE25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_160181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003251">
        <property type="protein sequence ID" value="GIX82560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8687" checksum="682235DC17689834" modified="2024-11-27" version="1">MPSSANGKLLDYAGYLVYVPLSSKDSVDDRLYSPPKYVQQFYINGHLGVPLIHHNITLTCSTLVTQQICYFADYGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGC8</accession>
    <name>A0AAV4NGC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_157271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003268">
        <property type="protein sequence ID" value="GIX82766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8437" checksum="E654A96214B6102F" modified="2024-11-27" version="1">MSESAPNRKDKDRRPHKFLLPTLPSDDLLSGSEIALRWSNYGNGNGEGRHQRLNPKNQFSGNYIPWLDVRSSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NP63</accession>
    <name>A0AAV4NP63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_606661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003599">
        <property type="protein sequence ID" value="GIX86566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NP63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11218" checksum="8D88013893300DBC" modified="2024-11-27" version="1">MSSVNMELDKIMENGSYQVPSKITFRAPKLIYDQLTIYDLEIPNLTTSINMTTTTVDVKNTSEHITNYVNYSQDTPYLGLFQRKPFWVLLHSQLCHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUF3</accession>
    <name>A0AAV4NUF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_242761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021277">
        <property type="protein sequence ID" value="GIX87930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="26282" checksum="C7DE14E3DAE56EFC" modified="2024-11-27" version="1">MELKQRKLTCKLLKKSFLIPSGTINLDFYSTLRTESGRTKTHSIAAGHNFRRKRERTVNALEGVVLLFSLLGMSRKLEKRTVARDRKKVKPKDENAFRELLDRGQWMKQGESNFFSSDEKNASRMQWDCTKEKSRIGQQCKRGKGLRNGTETQVEGGGYKTQLENKIVARDRKKVKPKDENAFHELLDRGQWVKQGDSNFFLLLMKRMHQECNGTAQKKSQNWQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZU9</accession>
    <name>A0AAV4NZU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_195781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003943">
        <property type="protein sequence ID" value="GIX90487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9749" checksum="E008CCE86F073CFD" modified="2024-11-27" version="1">MEVNEVSELNCCCMYEIASTYSTGKLETCLWQNNFAHIITTECALTKINQILMMGVHSWRLPRTGLLMKYFRKEVDQEKERLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2D1</accession>
    <name>A0AAV4P2D1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_156781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003897">
        <property type="protein sequence ID" value="GIX89921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2D1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10397" checksum="DEAB269549488E27" modified="2024-11-27" version="1">MSKITFHFTKPSAWGICTTCNRMTPVKSFENYTMREILRTNGETLNLVLDPSTETAFKYEDANHPVIKIKPKSPNSLFRSWTGRYAHREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4M6</accession>
    <name>A0AAV4P4M6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_747081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004037">
        <property type="protein sequence ID" value="GIX91579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4M6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47641">
        <property type="entry name" value="PERIAXIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47641:SF10">
        <property type="entry name" value="SERINE-RICH 25 KDA ANTIGEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="17860" checksum="E691FDAD18C44CF8" modified="2024-11-27" version="1">MTMPKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKDHISKMDKNHISKMDKDHIPKMDKDHISKWTRTTYFKERQGPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6I9</accession>
    <name>A0AAV4P6I9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CENP-F_N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_264506_1</name>
        <name evidence="3" type="ORF">CEXT_304401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021711">
        <property type="protein sequence ID" value="GIX92671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051310">
        <property type="term" value="P:metaphase chromosome alignment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043513">
        <property type="entry name" value="Cenp-F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018463">
        <property type="entry name" value="Centromere_CenpF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18874:SF10">
        <property type="entry name" value="CENTROMERE PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18874">
        <property type="entry name" value="CMF/LEK/CENP CELL DIVISION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10481">
        <property type="entry name" value="CENP-F_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centromere protein Cenp-F N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX92671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="37325" checksum="DCED1F19C7E615A1" modified="2024-11-27" version="1">MDWASSEWKQNLAPLVIQKINVLEEKLKSSKKRQQKQLQCDCLELALEKEKRKVEKEKQQTIEVQRELQSLAEACKDYENKQQKLQSEIHNRDSRIGSLEGLLTQAKKDNCRLQQLENDFKDLRGIRETAIIEREKKRQSLTLDQNNAQEQKSRMFSDSVNENSGINIFDDKENKKILRENDVHQSLMNKIAEQDRTIEELKTKLSLMDNHEIIKESSHILAKTPGRTKFETVVDASPVIKARNNLNVWDSFASTPAKENKDTILRHHSDSIALGSGDEKLVALQTRLKQLCQELDCQRHNFEASKKFHRAKVQGKRNCIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8G4</accession>
    <name>A0AAV4P8G4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_19949</name>
        <name evidence="3" type="ORF">CEXT_594721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021580">
        <property type="protein sequence ID" value="GIX91407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8G4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF237">
        <property type="entry name" value="MIND-MELD, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="2">
        <location>
            <begin position="26"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX91407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16842" checksum="729809389A8FFC10" modified="2024-11-27" version="1">MHEWGFKQFRIRPPTRIKRDVRQVYKFIELALVIDQAMFENRNSTKAEVVSDAIQILNCVDLYFKTVNTRVSVVYVETWAHGDQIDIIADVRQTLLNLLDYTSRKLYKVAKDATHLITGKHFRGSEVGMAVPDSICTAKAVGISEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PED4</accession>
    <name>A0AAV4PED4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_756651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004369">
        <property type="protein sequence ID" value="GIX94383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PED4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12242" checksum="84517EFE2A30BFEB" modified="2024-11-27" version="1">MKNFAGNFLVAVSMIAMLLGTVMVPGYEAMHHHGYGGGGIAEMLASGLVIELIRNHYGRRRRSVEGYAHEHEERPIVEGMKVLTMYPTSLAVHIHVYMCKIHLYSFKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLG0</accession>
    <name>A0AAV4PLG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_453161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004726">
        <property type="protein sequence ID" value="GIX96996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16506" checksum="63D45ECA4DD33960" modified="2024-11-27" version="1">MDAHLRFIFHCLRVSNALCHNFHENPIPCVQDLAAAALLCKEPESKGKELATTATKQPQTQKVHPHFGLGSQDVKRQDALWIEINRWNESLPEVNAVLNLNKWTLFCGSFFTVYGFQMLFLPQFPRKSHPKHTGLSSSNPPLQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPZ8</accession>
    <name>A0AAV4PPZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cancer-related nucleoside-triphosphatase homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NTPCR</name>
        <name evidence="4" type="ORF">CEXT_64351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004844">
        <property type="protein sequence ID" value="GIX97985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004948">
        <property type="entry name" value="Nuc-triphosphatase_THEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43146">
        <property type="entry name" value="CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43146:SF1">
        <property type="entry name" value="CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03266">
        <property type="entry name" value="NTPase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX97985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19102" checksum="C3A1ED11A388976F" modified="2024-11-27" version="1">MSRIGKTSVIRKACEILKEKNIEFQGFFTEEVKNGRERIGFDIVTTLGKRNILARVSDSSARKGPKVGKYTVDVSSFEALVLPVFDAPSSILILDEIGKMELFSKPFLAKAQEVFSKSNVRVLATIPVVKRVLPFVDELRNRKDCIVIEVTRENRNNLPHEIVQQLLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSG8</accession>
    <name>A0AAV4PSG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_246081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004963">
        <property type="protein sequence ID" value="GIX98786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="14711" checksum="84B5E6704BF82031" modified="2024-11-27" version="1">MSRVLYSKKTPNTHSTNGLQTLNRREENLGREFIKAIWNKKCGVTHSFVLEVGGDGVGAMSEHFEHLGDGPPTVGAGARPVGLGHHVVRGRGAVGGQGGGGAHHRRPGQRAARHAGSEKEKKMQTNQENSRLFTSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWR7</accession>
    <name>A0AAV4PWR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein ERGIC-53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LMAN1</name>
        <name evidence="10" type="ORF">CEXT_233861</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005330">
        <property type="protein sequence ID" value="GIY01519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043921207" evidence="8">
        <location>
            <begin position="18"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY01519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="459" mass="52034" checksum="E64F4EFDB3AA1E4E" modified="2024-11-27" version="1">MLYIFLLICLQIFVVFCELPHHKFEYKYSFKGPYLAQKDGTVPFWEHFGNAIASEEMVRITPSLRRKGVHFLLNSNISFWFTENKGVEGPVFGSNDHWIGLGVFFDSFDNDNRGNNPYIMAMYNDGTKAFDQSDGVAQQLAGCQRDFRNKPFPVRAKIEYYKNVLTILFHNGNSNNDEDFELCVRAENIYLPQHGYFGLSAATGGLADDHDALKFLTYSLYPPGTQPTSQNIGDAEKEKFSKEYEEYKDKLEKQKEEFRKEHPDEAKRKDMEFNPDEAYETSQQRELQQIFQGQSSIFEILRGLHRKIDEVIGRVPQGQGMPPPQVAGGSLGRHEIEALLGGQREIVQSARDIKSFVTDIHQRTGTIIAKQSEQGKPAGGGLAFEANALFQDVKESLNIVKRDLAAVAAKNQGGPCPVVQPVSCLTTTYFFIFMSIQIVVIIGYITYQSNKESQAKKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3U3</accession>
    <name>A0AAV4Q3U3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_619741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005647">
        <property type="protein sequence ID" value="GIY03994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3U3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="20591" checksum="4147CAA9559A127B" modified="2024-11-27" version="1">MNTLKYTRLREEGSLNERTFKRAIVQKCDWAYEDFEIAEMVQDSTMRMLQGRFRKEDDKNTCLRKSIDTLMTVGRIVRTLREIHKLYYEQLPEDFEETACSVIAKVVNKVVEKYLQSMGLSNSLKFWRDLEDWHLSRENGDHFSLPYPTSQILEYFSFVFEHLSIFQRMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3U8</accession>
    <name>A0AAV4Q3U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reticulon-4-interacting protein 1 homolog, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rtn4ip1</name>
        <name evidence="2" type="ORF">CEXT_56951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005736">
        <property type="protein sequence ID" value="GIY04613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="294" mass="32995" checksum="1A906779F383F44B" modified="2024-11-27" version="1">MLKSTSFGASKRESIEVRTDLPIPKILKENEVLIKVIAAGLDNIDLLVTKGYGRCIRSHIRENNEHIQDESTIIMGRECSGIVLNIGKDVTTVSKGDEVWAVSAYCLEGLMAEYVVIKENQVALKPKNLTFEAAASMPYTAIQACNALLKASLNSKSTKGKRILLVTGNSPVGLFAMQLLKSWGGDVTTAVPTAGLPMCHELGADDVIVYTVTDFETELRKRKTMMLQVVAWIKKLKQGMLTNFWWDNFSYDKEYLYMTSIFVEEEKKNDRNFLTTVRLQKLRLSLVDDSTRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIY5</accession>
    <name>A0AAV4QIY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_187504_1</name>
        <name evidence="2" type="ORF">CEXT_764281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006455">
        <property type="protein sequence ID" value="GIY10013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="425" mass="46697" checksum="77577BAC43157847" modified="2024-11-27" version="1">MTGSDLNTHEDSSDVSPMSSNYSLTPSTTENDQDSQSIKDAEGVKVEENKGEDPTISGIEAPELPPEVRNMIWKIVMGIKDKVDDLIMASEKKTIDEIVMLKERIKQQDALIEYLEMRCAQEGVGDASKNPEGVQMPPPVPVEKSSPPNKPSEDSAVSSLDAPSPVDLMTDVKFERGRYVAGGISSEHSCPETPRETLPPATSLQRGGRARDALPPLFTEALHRKLPAAHDVRGAAVLAQEVQRITSQIRFFIFIGATPSWPDVVPLNKSFAAKVRRVLAKVRVNRDSDDQSSSETSSPQSSYKWPQPATKSEDKKARRSSTGSTNLSTLFHQKSTPNKKYQSNPEPEDTSNRRYGSDGNPVVKRILPTITESSSFDSLRDSPLLSHASTQPVISMPNLDNDQLTVVIDMTDAHEELSMKDMSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRX9</accession>
    <name>A0AAV4QRX9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-ribosylation factor-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ARL2</name>
        <name evidence="9" type="ORF">CEXT_561321</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006662">
        <property type="protein sequence ID" value="GIY11579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051649">
        <property type="term" value="P:establishment of localization in cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04154">
        <property type="entry name" value="Arl2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000393">
        <property type="entry name" value="ADP-ribosylation factor-like 2, arl2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045873">
        <property type="entry name" value="Arl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="137"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY11579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="22313" checksum="FAC01EB7B48D31AD" modified="2024-11-27" version="1">MGLLTILKKMKQKEKEMRLLMLGLDNAGKTTILKKFNGEDISIISPTLGFNIKTLEHRGLVFSVALLIFVSFKLNMWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRRRLQDCKDELHTLLLEERLSGATLLVFANKQDLPGALTAEDIKELLELDLIKTHHWRIIPCSAVTGENLLLGIDWILDDIAARIFTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYV7</accession>
    <name>A0AAV4QYV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FYVE and coiled-coil domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_688992</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007035">
        <property type="protein sequence ID" value="GIY14026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072383">
        <property type="term" value="P:plus-end-directed vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901098">
        <property type="term" value="P:positive regulation of autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15730">
        <property type="entry name" value="FYVE_EEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46753">
        <property type="entry name" value="FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46753:SF2">
        <property type="entry name" value="FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RUN" evidence="7">
        <location>
            <begin position="33"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="1029"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="473"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="823"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="894"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="976"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY14026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1294" mass="148351" checksum="E604AEE2A674510C" modified="2024-11-27" version="1">MASCTVTSKALLDIEACIVELKKQFSVEKIPINDDCTVLHQLEEKLETILLLGLKREWWCFWSKKRSYWDYIVTCFSVSKRLHEGIKFVKSNSELKSSLGRGRALIRFCFMQKCLADTLQSCFIDHKTTRDFYSDRCLPLQPKRKVFVPFGNEVSFMNMDSGSNDFSSKISNEIEIHDTDNDVKADCEMTNNHNANSINVTKNCVEDIDTELNLHSSSNLKTQCSTLNDKSNLIDVSNSEISASNISSNLELKSLESILTVCDSSALTNLNFTKSFLQENIDNLLETEINPFHPDISNSLKKLILEMKAVLNNLENSINLSIKDPTALSQITCLKIIRDCVEKSFLINSSVKDNESLYDRICFLKDKLHSFGLLKVQTENNVDFKNNSKLLDESITNAIVVPECINFEHSEDMGNNFLESLTILRNSSTKLHTLNNQASSLKLLLDSSHKLNENLISRIQDQELHMKGITKQLEEAHNLLSVMKKQHQKLQSAENIVKYDLQEKRKLLTKLKQQLETTRENCNLVRLKNSKSEAEWQTLRKEFVQRNKQNSEESGFIDDKGIEDQTSAVVNSVYDCNINDNVPDNVLPLDNNDIETKYELKKNRLQLLEEQCQILCTNLKNSSKKRKEIDYRLESWCKAIESSHKENSHKLTEILSSEEGKSTIDESTSEKIIIDSNSDVDSSLSSPEIGSLNSNCCSFIPQDSNIISTDLSISLQSLKNDEFIPSINLECNQSKSPFEEENSIHSDHILKEIGDNSSESIENAASSCALVESVEFFKEAKENQMQTLIQSTSDVLTQVKPYEIPCSYEESQLVQSPSCNSTFEDLSELVSKLEEEKKMLQLKCQDLEIKIVMISDEFNQKIQELKLSEAAKKQEVVALQFQLNSEVLKYESIIKEFSNNNEGLKEMKQKVSDQEQLIFTLEEALAEIQVEREGEKEHQWEQLQDIQLALSTREEECVSLSSKMLEEFKMSNLKDREILENEIMHLRNDTKELQKKVIRLLKEKDILWKANDRLRYFHKMQIDDRWIDDHEVSECLGCRSQFSFLLRKHHCRQCGRIFCSSCSNNWLSTPSSRRQIRVCNECYMHRIEIKTDVRRDSNVQYCEESEDEAVVDDMSLNLNRSSSLSSEIHSTIADSIISLPAMHVTNLKQKSHFTSAPELHFSLDNQDILKRSFLNESILPSHMEIIENDINGNILIKANDEAILPILNEVNSTSISWKFEPPCEAIPIMLVYEDATHCSQQTVMHQSSCETEGVIHLCLPGLYKFHFDNKSRPSSMLVHYSFKANILKEQEITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R222</accession>
    <name>A0AAV4R222_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_65651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007070">
        <property type="protein sequence ID" value="GIY14351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R222"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8771" checksum="6B38C03E62D4413A" modified="2024-11-27" version="1">MSSPPSNKKRALLCLREGNKPIQVQYLIRSLKRDSATQVKGYILQSESTLPITLMGLGRMLILKLTAPFQEGFIIPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R890</accession>
    <name>A0AAV4R890_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SLC6A3_2</name>
        <name evidence="2" type="ORF">CEXT_770321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007583">
        <property type="protein sequence ID" value="GIY18163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R890"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17689" checksum="6FDDA66396FE6861" modified="2024-11-27" version="1">MGGLESVITGILDECSTYFTKVKMNREIFLRHGHCSCDIFLRIPRQRYKDLFFKTQELEFIFFSQTFLFYTRQKPIPFQFLLGGGYMMYWFDTYSAGISLLCAALFEAIGVAWIYGCYCIRDYQQFYTSISRLCLPSWAVGLGWGLLLFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJ88</accession>
    <name>A0AAV4RJ88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_514981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008139">
        <property type="protein sequence ID" value="GIY22388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJ88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="13410" checksum="C5950995FEF50728" modified="2024-11-27" version="1">MLNIEVMPFYSRLHRCNVKYWRCFFISKSDAVLFYSRLHRCNVKYWRCFYLQKVMPFYSRLHRCNVKYSRRFSAPKVTLFYSRLHRCNVKYWRRFVSPKSDAVLQSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNL6</accession>
    <name>A0AAV4RNL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_16591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008222">
        <property type="protein sequence ID" value="GIY22972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043808732" evidence="3">
        <location>
            <begin position="17"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY22972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="24010" checksum="4075FAE5AE361732" modified="2024-11-27" version="1">MFKTIVVCAVITVAFAQYHQGGGGRGYQSQNELTTPYPRNYHPPAPVHYVNIGTDLAGDYKFGYDTGKGPLGQSFREETRLPDGTVKGAYGILDESGRQRIIRYTAGKGGFMAEGDGLGPAGVAPGPAPQPVANPHAAAPQAAYQPPPQQYSAPAQQYNPPQQQYNPPPQQYNPPQQQYRPAAQAPSQTGQWDPRSDPYYKDGPAFIDVERLSYNIGTAKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWG9</accession>
    <name>A0AAV4RWG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_31961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008625">
        <property type="protein sequence ID" value="GIY26100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11087" checksum="543E216F8EDCEB82" modified="2024-11-27" version="1">MISYRHGSTAMDAQYIYPTIKSRGHIPVSSNSEFPYQVFQQTEVSSLLEVKQPLIWHCFASAVLSTFQRIHIATAPQPWMPSTSSNECRDLAKAGSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWP0</accession>
    <name>A0AAV4RWP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_208131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008727">
        <property type="protein sequence ID" value="GIY26753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14250" checksum="2619E652BC77E659" modified="2024-11-27" version="1" fragment="single">NKNKVLLPLPKSISTGNTNVSYHTFPPFQFQIEIYSRFPHKLPRGSNAIYYYLPDDVSPVTSAADTASAPSRVPRAKKPNWCRKEESLYRRSLDRRQVNHHLTRIRHTLSIINIKMSYDMHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYQ9</accession>
    <name>A0AAV4RYQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_446911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008585">
        <property type="protein sequence ID" value="GIY25839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8578" checksum="89CDBC5052693561" modified="2024-11-27" version="1">MANHSCRRQEAYCRVKALAEMCWFGRHVKCMEGGNNCACDGHQARCLEVVCCCFTLAEWIKLCGFHITINIVPSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8H3</accession>
    <name>A0AAV4S8H3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_530861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009202">
        <property type="protein sequence ID" value="GIY30289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8H3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11460" checksum="F5AFBE28D04FBE74" modified="2024-11-27" version="1">MEIDVLTLSCNFEGACLKIVYNLFPFISNSQRAFQWTDHTHPCIDKDSNGLYPLAIQLEPNKRAFNGQIMVIFGIENESSLNPGIDKVSSLIFGVPINLVSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDR5</accession>
    <name>A0AAV4SDR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNase H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009400">
        <property type="protein sequence ID" value="GIY31627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="24529" checksum="68F0A0CFB67CF0F0" modified="2024-11-27" version="1">MDSVQHRASKIIIGAVSSTNNNKVEQEWGLPSLGNRRNLATSKFINRLLSNNMDHISTRVFNEWKGSTRLKRSSTVQLDKDIRSRINLEHSSLNFVQEPLFPRKPPSETKFGLKLLFETIQKRRPNILKQKGLDTIDKFSQDNLAIAYTDGSSDKFLNKGGFFILLPNRSKYHHKMNTGLIASNFTSELIANKETVVLYLNDSDISGLTDGLVIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMT2</accession>
    <name>A0AAV4SMT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_779111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009751">
        <property type="protein sequence ID" value="GIY34284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9203" checksum="9118A554290137AF" modified="2024-11-27" version="1">MDGRSLQTTLREIPPPRHKEQLVFLNGTISWSCGHTQIRVLKENKSFRGFHAYDPNTKHSGRKSTLLLQMDPLQRVTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SN95</accession>
    <name>A0AAV4SN95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009801">
        <property type="protein sequence ID" value="GIY34726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SN95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9071" checksum="FF730F705A50B807" modified="2024-11-27" version="1">MNALPLFSGAACRALPPPPPSDATFSNKKFLKGQGSREGSGKVWPLEVHRFYPVALGAAASEATVWGLDFSSGDHFRSRLRELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SW17</accession>
    <name>A0AAV4SW17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010341">
        <property type="protein sequence ID" value="GIY38663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SW17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13646" checksum="9E2F0A0842313A2B" modified="2024-11-27" version="1">MLRVGMFSIGCRKEALHDPECVKPWRLGVGVQLDAVVADYCRLFKHSINTFMLKSEASKVHFSSPCHQIALLPYKTIIQTQYIGYSSLSNFATPSTGVQYLPPTLVTGAITTTRNPTVPACLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZW2</accession>
    <name>A0AAV4SZW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinesin-like protein KIF13A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Kif13a</name>
        <name evidence="9" type="ORF">CEXT_502261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010383">
        <property type="protein sequence ID" value="GIY38969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22706">
        <property type="entry name" value="FHA_KIF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043764031" evidence="7">
        <location>
            <begin position="17"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="1"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY38969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="478" mass="53270" checksum="DECB8958ED55402E" modified="2024-11-27" version="1">MCLNAFHFFSLSSVSATFLLMPFYSKQPKSFAFDQCFWSFNENHQHYASQETVFNSLGADILDNAFQGYNACILAYGQTGEVGKSFTMMGSEDNKGLIPRLCDALFERIIASGSQSDYKVEVSYMEIYNEKVHDLLDPKGCKQTLKVREHNILGPYVDGLSTLAVSSYEEINNLMTEGNKSRTVAATNMNSESSRSHAVFTITLTCTITDDFSGVTEGSNINKSLTTLGLVISKLADQSCGKTKDKFVAYRDSVLTWLLKDNLGGNSRTVMVATISPAADNYDETLSTLRYADRAKRIVNHAVVNEDPNARIIRDLRDEVEMLKEQLKSTTERQQALEQMGISVQASGIKVEQDKYYLVNLNADPSLNELLVYYLKDKTVVGYPGASSDLDIQLSGLGIMPKHCTISIENSDLFLVPENGARTCVNGSVVVNRIQLHHGDRILWGNNHFSESTVQKLAIVIVQKFQSVLWIMILLERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4T0</accession>
    <name>A0AAV4T4T0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_56362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010601">
        <property type="protein sequence ID" value="GIY40351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4T0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="21232" checksum="7ABB5769C92D84D4" modified="2024-11-27" version="1">MKADSYIQEVEKCIQSFKVQLEKQQKELKEDERSTLNLLSVLYKKEFPKQNLNLLDPMKLSFPNRSVVNSLFKDDKTENFLFNLGQGNKRDHLAAERRAEYNAYLEKKERQFQTHRKVLEESRSVTPRSILESVDYEKVLAKRKEEESKFRNLNYAEPSVDNNISPNLKFPLKKILIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8Q7</accession>
    <name>A0AAV4T8Q7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_812481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010743">
        <property type="protein sequence ID" value="GIY41711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8Q7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9242" checksum="9E73ADA184BBA521" modified="2024-11-27" version="1">MCPPLAIMISCKLSPEPRREKYPHKFPFRNAFFPKKRHSQRRRGDYIRKAVRVINGHFFSSSKSPSAHLSVQMVDVDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGB3</accession>
    <name>A0AAV4TGB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_151121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011139">
        <property type="protein sequence ID" value="GIY44437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="51" mass="5399" checksum="0176AA2DEB1F7F74" modified="2024-11-27" version="1" fragment="single">MRSVFSSQSPPLHRGGAHHRDHQSVHPGVLATLCPATAPFSSTTCGTGRME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TP29</accession>
    <name>A0AAV4TP29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_85171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011643">
        <property type="protein sequence ID" value="GIY47890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TP29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11563" checksum="8326B23A3AF9EA85" modified="2024-11-27" version="1">MSNQLPCVILMPVLQFVQKAKEVPFLDIIMKENSFAQHCLKLADSDRRFGSYKEVYQHTLPNYRLLAYEHQNLCDYGALRNNKRSMRRPQCQLLTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TY58</accession>
    <name>A0AAV4TY58_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_266101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011936">
        <property type="protein sequence ID" value="GIY50086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TY58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY50086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="288" mass="32301" checksum="AB28DBE3A92A207D" modified="2024-11-27" version="1">MSKDERKFDSFAEIFSDEEENTSVLESLRRAPAGSNVQYQLARGNVGDASNEPAADLFHRTSGLRNPICSDMGAEGGQNVVRSSENVQQSAEYSLLQPASNKRNISDTNDSSTECSVWNKKTCYCQMNLNESRCQLFDLSIREASYKTDGIRDGEINSCQKNQSSTSASSEEYSSLALSSFKTKGQRKIHVCDVCKREFPFLSKLEAHMRTHTDTILNIRKNAPFVMFISTRRSLCNFINVKNCSNVLSVLWEFPATEGYGPSTLPLHQSARLNYCCNNLIKHIINTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3A8</accession>
    <name>A0AAV4U3A8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_375571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012211">
        <property type="protein sequence ID" value="GIY52205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3A8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY52205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10223" checksum="66D806B15E41ECD6" modified="2024-11-27" version="1">MKQQHDLEEAGSSSNFSSAPINTSGLGERHKNNNYDNSRKKNTATRAICVAQVISRQCYQISKLVQLWFRMGICIAFNEFILNNFLFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB13</accession>
    <name>A0AAV4UB13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_184061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012573">
        <property type="protein sequence ID" value="GIY54916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14832" checksum="CEE48B9830D62091" modified="2024-11-27" version="1">MPATHLISIYIHHITLSQIVTLRESNLRFSKSFDIRVREVQNTLYLSNNSLQFFILFLKTFVHLESLRSLLSLPHQASCRFSVFTEKVSRELLEFLSSQSQSVELAAQEYRPCSYSFEKNSGPHHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQ14</accession>
    <name>A0AAV4UQ14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein flightless-1 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Flii</name>
        <name evidence="6" type="ORF">CEXT_225911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013228">
        <property type="protein sequence ID" value="GIY59659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQ14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11290">
        <property type="entry name" value="gelsolin_S1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000054">
        <property type="entry name" value="FLII, actin remodeling protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000021">
        <property type="entry name" value="protein flightless-1 homolog isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00597">
        <property type="entry name" value="GELSOLIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="5">
        <location>
            <begin position="235"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="4">
        <location>
            <begin position="501"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="405"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY59659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="619" mass="70000" checksum="334E01F6003DA021" modified="2024-11-27" version="1">MAVTGVLPFVRGIDFTGNDFQEDYFPKAVSEMTGLRWLKLNKTNIDWIPDELGNLQKLEVLSLVRNNLVTIHGEVTALPCLRYVNCRYNKLKNSGIPVDIFELEDLAVVDFSHNCLREIPRDLEHGKGLLVIENIPSQLFVNLTDLLHLDLSNNKLESLPPQMRRLVNLQTLKLNNNPLGHNQLRQLPALVALQTLHMANTQRSLSNVPTSLDSLTNLQDVDFSQNSLPRVPDALYTLPNLKRLNLSENCIIDISSDVGDLWKNLVTLNLSRNKLKALPATLCKLSKLRRLYINDNQLDFDGIPSGIGKLYSLEVFMASNNNLEMIPEGVVRCGRLKKLVLSNNRLITLPEAIHLLTDLEVLDLHGNPDLIMPPKPEELIMGSGSEYYNIDFSLSTQLRLAGATTNNPVAAPAHSKDPIARKQRLRRKKDDEVDSDQAKVLKGMSDLAKDKKDFALDDKNVSLKPKRWDEALEKPPLDYSDFFDDEVGQVPGLTCWEIENFVPNQVDEALIGKFYEGDCYIILKTLLDENQSLDYQIFYWIGSHATLDKKACSAIHAVNLRNFLGAQCRTIREEQGDESDEFLDLFGSDIVYIEGGRTASGFYTIEEVEYIPRLYRLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTK0</accession>
    <name>A0AAV4UTK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Collagen alpha-2(IV) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_723451</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="8">Trimers of two alpha 1(IV) and one alpha 2(IV) chain. Type IV collagen forms a mesh-like network linked through intermolecular interactions between 7S domains and between NC1 domains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
            <location evidence="1">Basement membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013441">
        <property type="protein sequence ID" value="GIY61236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030020">
        <property type="term" value="F:extracellular matrix structural constituent conferring tensile strength"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009792">
        <property type="term" value="P:embryo development ending in birth or egg hatching"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.240.10:FF:000001">
        <property type="entry name" value="Collagen IV alpha 1 chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.240.10">
        <property type="entry name" value="Collagen IV, non-collagenous"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001442">
        <property type="entry name" value="Collagen_IV_NC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036954">
        <property type="entry name" value="Collagen_IV_NC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050149">
        <property type="entry name" value="Collagen_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023:SF1112">
        <property type="entry name" value="COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01413">
        <property type="entry name" value="C4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SMART" id="SM00111">
        <property type="entry name" value="C4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51403">
        <property type="entry name" value="NC1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0084">Basement membrane</keyword>
    <keyword evidence="6 11" id="KW-0176">Collagen</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Collagen IV NC1" evidence="10">
        <location>
            <begin position="1537"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="307"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1160"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1406"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1447"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="632"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="731"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="817"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="985"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1169"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1244"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1417"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1515"/>
            <end position="1527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00064856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY61236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1766" mass="172257" checksum="5C47F07068E91F2F" modified="2024-11-27" version="1">MEAIWAFQSMCFGYTQQSYQYPQQYHYPAANNYERQYNQTGKPCVGCDNGGCKCIGEKGSRGTPGPPGPQGSPGLRGFEGPEGPTGEKGLKGEIGVSGPRGPKGDRGKMGVPGYPGVNGIPGLPGQMGPRGPPGMDGCNGTDGRPGVDGYPGDPGPRGFPGPPGYKGEKGEPAIGPPGLKGQKGEQGRDGAPGKPGPPGADGRPGTKGERGIPGPHGSKGERGISGDKGNMGVGFQGLKGERGDRGLTGPPGPRGACDGYFLEKKGVTGESGERGDRGHNGQPGLMGPPGDIGMVGEKGLPGYPGPRGKDGFPGPPGVQGFKGDRGEDGLPGLDGLSGMKGESGDLGIPGPRGLPGPPGPPGGIEGRAGPPGPPGPSGITGPQGYPGTDGLPGEIGPRGPQGPPGGPGIPGFPGREGPPGLKGGKGDAGLPGLEGLPGPPGLPGAPGPKGEPGIKGSPGLSIVGPGGMDGSPGLDGLTGQKGETGPKGERGAPGDTVEGIPGLPGVPGPKGERGFSGLPGRPGLPGLSGPKGEKGGSCITCIPGAKGEKGERGLDALPGLQGLRGEPGLPGPLGPKGDDGFPGLVGPPGDEGRPGIPGRDGAKGLPGPPAVIPTDLVLGEKGDKGDAGIQGLPGLPGRDGLPGQPGLPGPSGPIGLVGDKGAQGFPGAPGRPGSPGLPGIIGLKGERGFGIPGSPGERGERGSPGLPGLIGEVGQKGEAGKLPDKEDLIFPPGPRGPPGPPGYPGVDGLQGFPGISGKPGLDGFPGDKGEPGDNGLPGPPGPRGLPGPRGDKGGTGPMGFPGAVGPRGDDGLPGLPGFKGGKGEQGIPGIGRPGQSGLPGLPGPKGDPGFPGPPGLQGERGLPGFPGIKGEVGDAGLPGLSGSKGNKGEPAREGLPGPPGEPGVRGFDGQKGIPGPKGDPGLPGFEGLPGDKGNPGLPGLPGLPGFDGPPGQPGRSGQDGLNGLPGISGQKGERGIAGFPGSPGPVGLDGLPGLMGEKGDRGLPGIPGTDGFPGTSGKKGEPGLPGFPGVKGQPGDAATKGEKGEAGFPGLIGLPGNPGPPGLDGFPGAKGDVGLPGRGLPGLPGPPGERGLEGPPGLPGLPGIKGDGGLPGFSGSKGESGLSGLPGFPGQRGLPGQPGLPGFKGDAGFPGIPGLKGEVGDAGLPGLPGPTGGRGDLGAPGLPGLDGFKGEKGDAGYPGPPGDRADKGEKGQPGLPGVPGATGVKGSRGFDGIPGSPEKGDRGIPGLEGLPGPEGLRGSPGEPGLPGLTGPPGRPGLGIKGDRGLPGKPGIDGFPGQPGSKGESGLPGFPGARGQMGDEGLPGFPGQKGELGDSGFPGPPGRDGSPGLKGESGLPGLPGIKGERGLVGLNGPPGFRGPPGVPGREGLPGLPGFPGPKGIGGLPGQPGFPGPKGDAGFPGQPGLEGPPGEIGLQGQKGEKGFTPPLNLLRGPKGEPGFPGTPGEPGTPGTRGFDGPPGLPGEQGTPGQPGLPGLPGPIGIKGDRGVSGLPGPPGLPGARGQPGPAGLPGIPGGDYLMGILLVKHSQSNFVPTCPQGMQKLWDGYSLLYIEGNEKSHNQDLGFAGSCLRRFSTMPFLFCDFNSVCNYASRNDKSYWLSTNAPIPMMPVGESVIQEYISRCAVCEAPANAIAVHSQSLNIPDCPEGWNMLWIGYSFAMHTAAGAEGGGQSLSSPGSCLEDFRATPFIECNGARGTCHYFANKFSFWLTTIDPNDQFSRPVSTTLKAGDLRSRISRCSVCIKNSNYNTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXI5</accession>
    <name>A0AAV4UXI5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_678621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013621">
        <property type="protein sequence ID" value="GIY62473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13984" checksum="F904FBC9434BDB19" modified="2024-11-27" version="1">MNRTTVTLNTLPIILLYLLPLRRHECIRIGSNRNCGELYEKKKEKKKCREFLCKFPIMLIYHFFSKLALYKVLAKGENFYALVSLQTRANLSPFTKDYRGEEQTNEPRPIFGTPFYWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2Y2</accession>
    <name>A0AAV4V2Y2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_320671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013896">
        <property type="protein sequence ID" value="GIY64570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2Y2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9987" checksum="29B13FA49EEF928C" modified="2024-11-27" version="1">MVEIHRRMMNMYGEAYLSKTTMVEWCSKFNVEVNNILEPIVVGNESWCRHWKLESKASNIQWCHPSSQGAQEPVHLQEKEMLTCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6Z5</accession>
    <name>A0AAV4V6Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TBC1 domain family member 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Tbc1d15_1</name>
        <name evidence="1" type="ORF">CEXT_309211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013981">
        <property type="protein sequence ID" value="GIY65310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9939" checksum="764F5666817C57F5" modified="2024-11-27" version="1">MINDPYNTAMGGFSKVTNYFMDYLMNGTEHKHHRIDLTEMISNNLLHVNIDHHEEPGYELITCIDLPPRPEVTREESVTPRNGLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V811</accession>
    <name>A0AAV4V811_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_17113</name>
        <name evidence="4" type="ORF">CEXT_567401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014088">
        <property type="protein sequence ID" value="GIY66173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V811"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032222">
        <property type="term" value="P:regulation of synaptic transmission, cholinergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030431">
        <property type="term" value="P:sleep"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00117">
        <property type="entry name" value="TFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031424">
        <property type="entry name" value="QVR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050975">
        <property type="entry name" value="Sleep_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562">
        <property type="entry name" value="ATILLA, ISOFORM B-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562:SF14">
        <property type="entry name" value="PROTEIN QUIVER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17064">
        <property type="entry name" value="QVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043528712" description="Protein quiver" evidence="3">
        <location>
            <begin position="24"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY66173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="15940" checksum="0AFA835B682D2C04" modified="2024-11-27" version="1">MNYILNFVVISLFFYLRIHSVSCLKCHVCSSGNPGQEDCISIDPTQTKYLMECHGPMNASCRIQEQWVDFEVLRQKSDKRTIRQCASTPFDPSRPCYYRAGFGGKTNVCNCLGDGCNEATRTTAAATLLVTIGSFLFIKMLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VA18</accession>
    <name>A0AAV4VA18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alpha-actinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_608843</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-actinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014154">
        <property type="protein sequence ID" value="GIY66796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VA18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21216">
        <property type="entry name" value="CH_ACTN_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000004">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000001">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000004">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000005">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000002">
        <property type="entry name" value="Actinin, alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000003">
        <property type="entry name" value="Actinin, alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000148">
        <property type="entry name" value="alpha-actinin, sarcomeric isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000089">
        <property type="entry name" value="Spectrin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014837">
        <property type="entry name" value="EF-hand_Ca_insen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08726">
        <property type="entry name" value="EFhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01184">
        <property type="entry name" value="efhand_Ca_insen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="8">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="8">
        <location>
            <begin position="129"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="741"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="782"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY66796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="887" mass="102541" checksum="D8308C878D351266" modified="2024-11-27" version="1" fragment="single">WIIVKFKLHLWITFNFVKRVVYHDDDGWRIHGAGGGMGARGIARSSMGKTAAKDLHCLVETLPKPDRGKMRFHHIANVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGLIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSWKDGLAFCALIHRHRPDLLDYSKLTKDNPIHNLNLAFDVAEKYLNIPRMLDPEDMVNTPKPDEHINNTPMPDERAVMTYVSSYYHTFSGAKQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTTPWLENRTTDNTLVGVHKKLDEFRNYRRVHKPPRVEQKARLETNFNTLQTKLRLSNRPAYLPSEGKMVSDIHNAWKGLEMSEKGFEEWLLSEMMRLERLDHLAQKFKHKADIHEDWTQGKEEMLQSQDFRNCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYHDAASVNARCQRICDQWDRLGTLTQKRRSALEEAERVLEKIDTLHLEFAKRAAPFNNWLDGAREDLVDMFIVHTMEEIQGLIDAHEQFKQTLGEADKEHKSITALAQEVQTIATQCQIPGGIENPYTTLTSIDITTKWSDVKQMIPKRDQVLQTELMRQQSNERLRRKFAEKANAVGPWIERQMDSVAAIGMGMQGSLEDQLNKLKQFEVSVVQYRPHMDELEKCHQEIQEAMIFENRYTQYTMETLRVGWEQLLTSIHRNINEVENQILTRDSKGITGEQLNEFRMSFNHFDRNRTGRLAPEEYKSCLVSLGYNIRNDRQGEADFRRIMSVVDPNNTGYVHFDAFLDFMTRESTDSDTAEQIIDSFRILAGDKPYITAEELRRELPPDQAEYCIQRMGPFKGPGAIPGALDYMSFSTALYGESDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAI8</accession>
    <name>A0AAV4VAI8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_53731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014125">
        <property type="protein sequence ID" value="GIY66510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8590" checksum="0386506886520F08" modified="2024-11-27" version="1">MRPVEHGQVVDYASYMKCTTNPALARKQVFLSQCSGLKGLRNLLTSTALLWNRHHLPLVSSSSVTRCSNLFLRSVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDJ3</accession>
    <name>A0AAV4VDJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_723041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014366">
        <property type="protein sequence ID" value="GIY68342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10698" checksum="D1C91CBC43D3CC39" modified="2024-11-27" version="1">MATLEAVFLFSSACRAHSRAPTSLPSIACASIKQIAFEHRCALLSVKVTLVTLYLDSTVNLLPTSVASSPGKNNYFAIDEFSPGAPSHYNWTEAVLPLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGR3</accession>
    <name>A0AAV4VGR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_57791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014498">
        <property type="protein sequence ID" value="GIY69159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10802" checksum="8D9E6AD5B4A3213E" modified="2024-11-27" version="1">MARGLLEYLLMKRSDVSQGHQLLSFSGLAVSEVPPDCPEKGRSSHSSLIYKSSTIIFIGHKYSCQKFLSKNLCGFCTIIFKLIPNSQTPVCDFSLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VQP2</accession>
    <name>A0AAV4VQP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_207391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014898">
        <property type="protein sequence ID" value="GIY72121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VQP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12263" checksum="D776C632E00B6F77" modified="2024-11-27" version="1">MFVQNLLNDDKLNASNYTVDEYVDWKVLCCSDRGKEMEANLQYFFDTSVLQKHSAFRKVGQLAFNLKLLVMNWQKQNNSTKNELFYIIKIEEGLHVLHVGSKSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VXL4</accession>
    <name>A0AAV4VXL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_233701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015246">
        <property type="protein sequence ID" value="GIY74694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VXL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10939" checksum="E2F34B6E6A5D6800" modified="2024-11-27" version="1">MFSVKTQLYFNTKKKKKSLTPACTIFPHLKSCEKNNPSLPPACLNISIPTSSASFKTETMGHRFSHFYEPTLSNPINFCREVSAEEGSRKIFCLNSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VY58</accession>
    <name>A0AAV4VY58_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_709151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015295">
        <property type="protein sequence ID" value="GIY75053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VY58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16209" checksum="244CD6F80A918ED3" modified="2024-11-27" version="1">MGKKSTRGPSRGQGRGTLKPTIRENWYTSFSHMRTASPNENGNSEVRFCTRVWGGPGGGGEEHLISFLFLSFLDDRMYMVLRYKRFLVIGRILWNSADAVDAFEWIIMATKKKKKKKNLDGEESESELLGFMYCGPVVQIYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZI5</accession>
    <name>A0AAV4VZI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_633831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015340">
        <property type="protein sequence ID" value="GIY75418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="45" mass="5281" checksum="51B128D1EB90ED82" modified="2024-11-27" version="1" fragment="single">MRNAKEYISCVFLLVSIFTHFKEGIARDALRDIQCTLYDDAHNVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBW7</accession>
    <name>A0AAV4WBW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_235201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015966">
        <property type="protein sequence ID" value="GIY80117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19632" checksum="EAFFA792C98BF3EE" modified="2024-11-27" version="1">MSKVKGKSRLRYKGKFLDFYGKYSEKKCLGSRRFLSLETGRRRGDQIHNPFSGSHDIAGWVISSYGHSSSKLQPGIFPAPSKLVEILISHFETNPPVRVQRSLRRATCRPRSARGTTDRRTMSAARHALCQRSGGRLRIAALRPAATFGDASPSFPYTEMGNVKKKKMRGFKYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCZ9</accession>
    <name>A0AAV4WCZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016049">
        <property type="protein sequence ID" value="GIY80736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9304" checksum="08C4BA3CB66CE122" modified="2024-11-27" version="1">MSRLCPEERCKRKHIEKTMGGSPLFPEVFSDDTSLIPGMTLIERGRFYFEEISIEEGEIQFFDVRRANVSSVGLKRFSALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WG05</accession>
    <name>A0AAV4WG05_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Centromere/kinetochore protein zw10 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Zw10</name>
        <name evidence="15" type="ORF">CEXT_267181</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ZW10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016102">
        <property type="protein sequence ID" value="GIY81293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WG05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048343">
        <property type="entry name" value="ZW10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048344">
        <property type="entry name" value="Zw10_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009361">
        <property type="entry name" value="Zw10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20666">
        <property type="entry name" value="ZW10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20665">
        <property type="entry name" value="Zw10_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06248">
        <property type="entry name" value="Zw10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="7" id="KW-0498">Mitosis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centromere/kinetochore protein zw10 N-terminal" evidence="11">
        <location>
            <begin position="27"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Centromere/kinetochore protein zw10 middle" evidence="12">
        <location>
            <begin position="191"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Centromere/kinetochore protein zw10 C-terminal" evidence="13">
        <location>
            <begin position="418"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="14">
        <location>
            <begin position="568"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY81293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="718" mass="82067" checksum="1C86A60688C5A996" modified="2024-11-27" version="1">MSSIVAEVLRSTKKLAKENVEVKVCDLKRKVEDINLEVHETLKTHYAEFCPRYIKVEKLLDDINDLSYEFDNLNNQIEKEIKPQMMTSVVELGDVVEDLKRIKSLITAVQCLCLAHQYLEEAKNAYSQGSYFISADSLLHYEKVLKDIGSKKEKNIAIISALEMEFILTKEMLTDCLTELFYRKLVIISSLAEKKNNLSIEINESIGSDDKSEILIALKLLKELKPFLEEFGAHFLHLICDTVLTNITNILIHSKEPSSIEIQIIKDHNPEPEEAFEALKTIFDFLQKEFFHLPITKKGEEARSLMSEFGSIIGEDFCSLVIEKCLNTAIPKQSKQSETFHKLIFTAEEFCKSLQCMEFLSSPRNKLLDFIHEMDTLPVDKMVQEFMGRARSLMQKNLHQTIEAGTESYEMTKSGTTFLFPRCQISVSVKELIGLLLEIKKEAKNISPVLAPRLYYAARNVCMLYTSVVFTYHKKGIENIPRQTAIYYNNCIYFAHQLCKISSLYQSDLQLKIPMTFVDLNPEIRKLGTEAFLTQMRNQKEQLLELLQEEEEYDSLLVDDGAVNKAEKAIRLCLCQLQQLKKVWDTVLPLEVYFKAIGTLFNTCLEEIISHVFSMEDIAAESAAQLDGIFSILLKQGRDLFKVSVVDNSASIHFYVKQWFKFQELQIILSASSREIVNRWGGGKGPLAAHFASAEVKHLIRALFLDTDGRAAVLVKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WG14</accession>
    <name>A0AAV4WG14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_801901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016094">
        <property type="protein sequence ID" value="GIY81193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WG14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10486" checksum="EBCEBEFB51958298" modified="2024-11-27" version="1">MEKGRAKETRRIIEATNTTDKEKTSHFTKPEAAVDELLSSPVSCSYEDPFVLPPTLDFYSSLRLDDLTTHRPEAFSPADNVPNDKEMTDNPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMN3</accession>
    <name>A0AAV4WMN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_44011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016356">
        <property type="protein sequence ID" value="GIY83225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12408" checksum="BD3E455DD697AB57" modified="2024-11-27" version="1">MNKDSMYRNGTGEDRILVGVRRERFGGVKLTLLEACIEYCADKEGCQKCSSNTYSWKDFLSKIPLLTFCEAVSVLLCSMNLEHVFLEGYELNNISRVRVEGLVAENEQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQ07</accession>
    <name>A0AAV4WQ07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_512441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016456">
        <property type="protein sequence ID" value="GIY84016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQ07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="13667" checksum="C3A36A280FBBB85D" modified="2024-11-27" version="1">MAPWRWTLPPQNYSPLVTQSTPAAQPPKGDSAPGLLPPLSSLLSHRPPPGSTFTVPPLPTTFAARCRLKWKKTPAPAPVEFPKQEAPAPAPAQLPAPAPAPAPAPAHFLSLFSGSQAPNFALVSASPFWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WR07</accession>
    <name>A0AAV4WR07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PDZ and LIM domain protein Zasp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Zasp52_3</name>
        <name evidence="7" type="ORF">CEXT_512431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016456">
        <property type="protein sequence ID" value="GIY84015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WR07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="114"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="54"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY84015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="376" mass="41024" checksum="0AD66CC8EA50064C" modified="2024-11-27" version="1">METFSMNVIAQTLSQHSEMLAPGVMGINFMKPEKPINTMSEVYKLVQEEEQCKVRSPTPGGCTSPPIFRPSKIPPSVPAKPQAPPAPAPVSAPPAPAPVALKKTAPAPEGPSQGPCSDCGRIIVGPFVNLNDRILHQECFNCSTCGASLKKYRIPQHKQQAHQPSLRHQRLPSLLQHLFRTTETRPGSGDSPLPTTPIASAPHTPGTAAGRRPAQIAHHLDPPAHPHPLQPHEPAPEPQLFGQSRLQGASPRSPSRHNLLCFRPSWSRPLQRSQTSQVTQVVQRTTQVSQSTQQVSQSSQSQYSLDYKQVIGGQSTRGVGGGNDGFLHQTTLTRVSQQMCFPQMSLIFDAKAVQLLCMDHLYPKLHVNMFLEVILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUM4</accession>
    <name>A0AAV4WUM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_737271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016670">
        <property type="protein sequence ID" value="GIY85610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8412" checksum="46A1190D63BA6D5E" modified="2024-11-27" version="1">MGDDCVLENPTPTSRGFYMDRFPLVSESRPPSPLIGAQSPTHHTHLKRNLEGKARIGMRHSETIMHFARYFVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WV68</accession>
    <name>A0AAV4WV68_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Sodium/potassium-transporting ATPase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">Atpalpha</name>
        <name evidence="24" type="ORF">CEXT_48751</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="19">This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.</text>
    </comment>
    <comment type="subunit">
        <text evidence="20">The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 21">Cell membrane</location>
            <topology evidence="1 21">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 21">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016692">
        <property type="protein sequence ID" value="GIY85805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WV68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000106">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000001">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000004">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005775">
        <property type="entry name" value="P-type_ATPase_IIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01106">
        <property type="entry name" value="ATPase-IIC_X-K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF13">
        <property type="entry name" value="SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16 21" id="KW-0406">Ion transport</keyword>
    <keyword evidence="17 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12 21" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 21" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0915">Sodium</keyword>
    <keyword evidence="18" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="7" id="KW-0740">Sodium/potassium transport</keyword>
    <keyword evidence="13" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 21" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="23">
        <location>
            <begin position="65"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="24">
        <location>
            <position position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00037422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00038795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU362084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="GIY85805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="851" mass="92937" checksum="10357F50EEB3E76D" modified="2024-11-27" version="1" fragment="single">MASQDKDDEQLARSDSFRLAVTPSIPDDGKTPDGKPKIVKKAMGTKGGKKGKPDLDELKQEVDMDEHKIPIEELYSRLGTNPETGLTAMQAREIYERDGPNALTPPKKIPEWVKFCKQLFGGFALLLWIGAVLCFIAYSIQVGTSEGSVEDNVSIVLATVVIVTGCFSYYQEARSSKIMESFKNMVPQYATIIREGQKHTLPAEDVVVGDLVEVKGGDRVPADIRVISAQGFKVDNSSLTGESEPQTRSPEMTNENPLETRNIAFFSTNCVEGTGRGIVINTGDRTVMGRIANLASGLEMGDTPIAREIAHFIHIITSVAVFLGVTFFIIAFILGYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSALFAGYFNRGLQYDKTSSGWKALSRVARLCSRAEFKPGQENVPILKECIGDASESAILKCMELATSNVMQYRENNPKVCEIPFNSTNKYHVTVHETDDSNNPSYLLCMKGAPERVLDRCSTIYINGKEKVLDDEMKEAFNNAYLELGGLGERVIDKKFKLLLHFIKHKESMQIFCDYLLPSDQYPSGYPFDADEQNFPIGGLRFLGLVSMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAKAIAKAVGIISEGNETVEDIAQRLNIPIDDVNPNDAKAAVIHGSELRDMETDQIDDILRNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEAYTLTSNIPEISPFLLFILADIPLPLGTVTILCIDLGTDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1F2</accession>
    <name>A0AAV4X1F2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein heavy chain 1, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dnah1</name>
        <name evidence="2" type="ORF">CEXT_298231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016954">
        <property type="protein sequence ID" value="GIY87573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1F2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="199" mass="23625" checksum="3BF8D49220D064DC" modified="2024-11-27" version="1">MDDDDFTTYWRIQELPQITMQRLDTRMASFDSEREIHGENLAVDLKQLEANIEHFSREVSSLAELWDTENTTNTATDIRKTRKEITMMGDRAQLLNKREKLFGKRSDRLFSEIEQLSQKLTPVELFWLNAAEFYKYRERVVSEEISMDPKELREKILEFQTNLEKSLAHFTKDLNPQIHNSIESVITEMNEFLKSKWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8R4</accession>
    <name>A0AAV4X8R4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_155471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000020">
        <property type="protein sequence ID" value="GIY91495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8R4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10600" checksum="D59D390BE1091509" modified="2024-11-27" version="1">MSEATGNTTPISKSEDISYFVVAPKPFYMKGICDRLSWRKEWTSLTDLLKRMCMTISSFSGLDPECLCTLFFARRNPSASTYLPILIWEWSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X947</accession>
    <name>A0AAV4X947_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017449">
        <property type="protein sequence ID" value="GIY91722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X947"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19432" checksum="6A47890DE964EDFF" modified="2024-11-27" version="1" fragment="single">ENDQDTVTVKTEQDMLAETIIGCSWVLYKNLSSKEELVLISFTSERTFERIAVKNDKDTVTVKTEQDKLHPKLLLVAVGYFTKSFSSKEELILVYFTSDRTFESEILSGYSYSENRTRHVTRNYYWLQLGTLRNLSSEEELILLRLRERSRGKKNAKWKELFEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9E6</accession>
    <name>A0AAV4X9E6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_796941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017460">
        <property type="protein sequence ID" value="GIY91812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9E6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13998" checksum="527230B96564ADB7" modified="2024-11-27" version="1">MCWVCINAYNYRKTRTTLMRGYLPTPDAKEPAKLELVLGPLRYLKSTDMKRESHESKFWCNSPSKSVVGEEWYSYFDFTWLSMLNVDLSLRCYCSKALAESSAKAFHACFSGPKKTIPDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCA7</accession>
    <name>A0AAV4XCA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_488331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017596">
        <property type="protein sequence ID" value="GIY92886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8067" checksum="DE95C419C56C05FD" modified="2024-11-27" version="1">MEQDFQLRLKTVLESEPCVWEPETGVDRGNGGKIPTVFGLTPTFEIIDLSNFLRREPFAQGDVLGGVKKEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCE5</accession>
    <name>A0AAV4XCE5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AVEN_227787_1</name>
        <name evidence="14" type="ORF">CEXT_605021</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000029">
        <property type="protein sequence ID" value="GIY91619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071222">
        <property type="term" value="P:cellular response to lipopolysaccharide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006955">
        <property type="term" value="P:immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051713">
        <property type="entry name" value="T-cell_Activation_Regulation"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25466:SF9">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25466">
        <property type="entry name" value="T-LYMPHOCYTE ACTIVATION ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="67"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY91619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="229" mass="25854" checksum="B91324ED253145F7" modified="2024-11-27" version="1">MQKAIDQQSPNAKATWVLNGKTIQPDGTKRILKKNQDLQISKAASKDNGVYTCIITLKKISITVSLSSVAVQNSKSDLEVELGGSFILFCNGVIVGRTFPTKLTQKWYHNTTLYKEYKKSKPQDINELTIKSSKYTDSGIYKCKIDEREGKARGWVTNVITVKVIPPIPLYIKLLPLAAILLVLLILIITILCLCLRRKESHNSKSGKSRRKRSRRVIKKKKKKAKIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH66</accession>
    <name>A0AAV4XH66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_800931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000234">
        <property type="protein sequence ID" value="GIY93109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8541" checksum="08204FDEEA6F63C0" modified="2024-11-27" version="1" fragment="single">LKPETSWVFRPTDVLRYKRLVEIAVTKQRTVSEGEGGACQFIGSSFLRCGKFNEPPFRHLPPALKSSHVILLMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHM4</accession>
    <name>A0AAV4XHM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_448311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000357">
        <property type="protein sequence ID" value="GIY94142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10564" checksum="83C7B835851814C5" modified="2024-11-27" version="1">MNRKVNTSHPFTPCSTPSAMYLARFARTSGWINIENERTRYAIYETRYKSLQFGISTVPIIHLSPISVVKVRGEVLGIKFMDVIDIANGEKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIX2</accession>
    <name>A0AAV4XIX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_60471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000472">
        <property type="protein sequence ID" value="GIY95020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18022" checksum="E4092CD3B8F7117F" modified="2024-11-27" version="1">MRECELPPPGRYFLLSYVLQEDTSHHTSVVIHKWYRGSASAQLPLVPIGSLGGSKPVSRRRSPMSDFVKMRSSVSRSEPPTHVSQLSAKTCRFFCQTSAGGFIDSNKSFLFKNAPRLAPSHSNKRRSFFPYPKYKNGKTRNRLSRKTKFESFTCDQPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJM9</accession>
    <name>A0AAV4XJM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SH2 domain-containing adapter protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Shb</name>
        <name evidence="5" type="ORF">CEXT_564121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017891">
        <property type="protein sequence ID" value="GIY95292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001784">
        <property type="term" value="F:phosphotyrosine residue binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051846">
        <property type="entry name" value="SH2_domain_adapters"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15127">
        <property type="entry name" value="HEAVYWEIGHT, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15127:SF32">
        <property type="entry name" value="HEAVYWEIGHT, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0727">SH2 domain</keyword>
    <feature type="domain" description="SH2" evidence="4">
        <location>
            <begin position="295"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="84"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY95292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="394" mass="44433" checksum="D4115BB0FBE958DB" modified="2024-11-27" version="1">MAVRHLYETAFDSTASPANADEDPAEILETSRRLCSPEPSVSQRPSPASSRSSTDSARRSSPRSPALHLKKLFTPWVCVKGNKNPESPIDVPQPHNNNPTEDKSKTFSPSVEFKKLDVADESKKNLNDRLPDTNTSSSSIDNSFNENNVHTVPYAVPSPSVQDNGYFADVSTSTVIQNYNYDTTNSTYSSQSSKEGWKTVTIDTHSGTNVAYDMKRRENELCNGGETTNSFQTSRTSREDMKRGSFESNSATRGNLWLDFSRAPKRARRHLCLDIKGPEEEDELEPTTYLKKQEWYHGSISRADAENLLRLMKKGSFLVRCSEKLKRQYLLSLKSSRGVMHVKIVQLANGKYVIKQQAQTFDSIPQLIQYFSTHILNIHEMNVYLSHPVVEKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLJ3</accession>
    <name>A0AAV4XLJ3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_380231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000539">
        <property type="protein sequence ID" value="GIY95537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017156">
        <property type="term" value="P:calcium-ion regulated exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF234">
        <property type="entry name" value="SYNAPTOTAGMIN-15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="78"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="20086" checksum="8BD6EF7284D2105D" modified="2024-11-27" version="1">MPSKNAEERILKATVLDSDRGKRYNVVGHALFPLKDIDLATDEMSVQWKDLIKDVDTVVPCDAGELLVSLCYNQNLERLTVTVCEAKGLKLPEGQTALDSFVKLIFLIENKQIKTKKTVAVKKSTDPKLLCRGPNKDKIVGRVVFGSYMFVRGKPLEHWNEAISAGHKQIRHWQKLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN09</accession>
    <name>A0AAV4XN09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_725431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017993">
        <property type="protein sequence ID" value="GIY96032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="9098" checksum="5BC59618E4AD38A5" modified="2024-11-27" version="1">MKLWYPPPVCGRIHSVGGTQYERVVKTAQYFKHGILGCHKKPDKFMEWRKIRLQGKRDFRHYKCNMRERISLPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZG3</accession>
    <name>A0AAV4XZG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_88841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001007">
        <property type="protein sequence ID" value="GIY99120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17226" checksum="2A4ADEB9DD16303C" modified="2024-11-27" version="1">MMYFSQVDEGHQWHPEDHRRQRQSVGEPGHLEPEEGAKRGRRQSTSVSCATALESGASKACWSSQLPTVWHMSACLIMDCEHVIMGVQYSYAVIAVTIKAYFRSSEYGVNLFDVVNFVENYALQRRINALKPESRLMQYWPNALYNLHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZH9</accession>
    <name>A0AAV4XZH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_7751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001174">
        <property type="protein sequence ID" value="GIZ00568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16539" checksum="5DD8953BBCF8D118" modified="2024-11-27" version="1">MENRFKIRAEPNTSVSLTGMGFTNSCSELSFLNKREAKFTLSQNSLIQDSTDTSHHEWLQLGPNTNSNSILYEMFSPETACNASTATGASIKFVVSSNGDDSESAASHKVSYEIHGAFCLRGNLMFELSQQMFRNCCRFAFLHLSSETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y010</accession>
    <name>A0AAV4Y010_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_402012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018573">
        <property type="protein sequence ID" value="GIZ00662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y010"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00322">
        <property type="entry name" value="FNR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052128">
        <property type="entry name" value="Oxidoreductase_NAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505:SF1">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="51"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ00662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="258" mass="29265" checksum="5BA81F17CBF17855" modified="2024-11-27" version="1">MITKIIESYCTQILKISHCFSSQRQIHSNVIRYSSRADFRMAPNVFHKRLVKIYTAVVEDVFNASSTIKILRLYIKEAGFSFKAGQWVDFYVPGIQEVTGYSMTSPPNEAKEKGILELAVKYGTFPPTHWVHNSCSPGGEVQIRVGGDFYYDPLANKKEAEANLLLIGGGVACFSRYFADIEREHPTLTCQYFVTRQPKTGPSPDSRIEEKNVGDSIKTLGKKTLCYVCGPSTMTDDVANMLLKIGIEKEYIRYEKWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0L7</accession>
    <name>A0AAV4Y0L7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbonic anhydrase-related protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CA10</name>
        <name evidence="4" type="ORF">CEXT_516971</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018428">
        <property type="protein sequence ID" value="GIY99525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF208">
        <property type="entry name" value="CARBONIC ANHYDRASE XA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY99525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="302" mass="33925" checksum="724D4AC8BB8F8A8E" modified="2024-11-27" version="1">MHVKRTLPTKEVDLPLFAVSESSSPDFWGLLNPEWSFCTKGRRQSPIDLNPGVLLYDPLLKDIQVDKNRVSGTIMNTGHSIIFRSENLDLESVVNITEGPLSYKYRFEEIHLHYGRTDDKGSEHTLSGYAFPAELQILGYNSDLYNNISEALAMRRSEGVVAIAVLLQMGQEARLQHLSVYDLLPDTHFFMTYDGSLTMPGCQETVTWIVMNRPIFITKQQLYILRKLMQGAQNNQKAPLGIISGPATLNQRVVRTNIDFERIEGERSVPRCATTCTTKQGSGPGTRDDDLQVLVSPSEKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0N6</accession>
    <name>A0AAV4Y0N6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_705061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018429">
        <property type="protein sequence ID" value="GIY99540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9742" checksum="1638B388A0316C73" modified="2024-11-27" version="1">MDELRNRRVMFKSKGKVLPSLYHRHFLRIFVRHSLGPKFSIEARTLCDHVPSGNFIVFRRVRIPWSDLFENAEQELQTIHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y265</accession>
    <name>A0AAV4Y265_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_132061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018666">
        <property type="protein sequence ID" value="GIZ01438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y265"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11658" checksum="12CCF9C028CDC645" modified="2024-11-27" version="1">MQMKTGRDPGGTSSGSLAADICSRNTDGWTLQRRIAVMGKSGKNPAALEGRKSLCARQSVDPRPPRAFSSFFRSVMMPEIMGELCKKKRARVLFLASRTVFHVLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5E4</accession>
    <name>A0AAV4Y5E4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Uracil phosphoribosyltransferase homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">uprt</name>
        <name evidence="10" type="ORF">CEXT_754091</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001339">
        <property type="protein sequence ID" value="GIZ01709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5E4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000026">
        <property type="entry name" value="Uracil phosphoribosyltransferase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="9">
        <location>
            <begin position="36"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIZ01709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="24956" checksum="3CF991F0DEDDC115" modified="2024-11-27" version="1">MLADVPDVLKPSQQANLNADIKTDEFGPNFKVILINDQVRELQTVIRDKNTNRSDFVFYADRLIRLVVEEGLNQLPYKRCGTYEGLKYLKGNCGVSIVRSGEAMEQGLRDCCRSIRIGKILIQSDEDTHEAHVVYAKFPEDIALRKVLLMYPIMSTGNTVIKSVKVLKDHGVKEDNIILLNLFCTPHAATSVMKAYPAMTILTSEVHPVAPNHFGQKYFGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5J6</accession>
    <name>A0AAV4Y5J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_688121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001470">
        <property type="protein sequence ID" value="GIZ02517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14106" checksum="258BE087BB8A589F" modified="2024-11-27" version="1">MLTSTHSWSTILSNADEFSCLIIILMRSHPVQEIPNAIKMADEYYLMNQGSSDSPDQRPPVKCGWEQTNHERGGRNPRELFMDALPTVQLRLDLDLWGKFYKVFLFLSEQYLLQILNEENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5M1</accession>
    <name>A0AAV4Y5M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_685371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018669">
        <property type="protein sequence ID" value="GIZ01449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10040" checksum="3F1230D627DFFFD0" modified="2024-11-27" version="1">MFESSSPTFQPGKCTRFICALSYDSCTHHSPEKIEQSASIFRILFGVQRAGWPLAIKYARQQDIQIDYLHVAKRTKGKLKRDNSELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6Z9</accession>
    <name>A0AAV4Y6Z9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_149041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018737">
        <property type="protein sequence ID" value="GIZ01929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6Z9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11207" checksum="2A3BA47E44A6991B" modified="2024-11-27" version="1">MALKISLGGCNQRRRSAINYGFMPTKNRLAAPQGFVRSSGRGPRSENYIAFPAIYSSGNVHHHTAHDVDGIRALNDIIVYSRAAIFSNSRKCFDAIRIILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y740</accession>
    <name>A0AAV4Y740_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_605061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001548">
        <property type="protein sequence ID" value="GIZ03087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y740"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10277" checksum="65B2D7603735F401" modified="2024-11-27" version="1">MDCLNRVLFCPRLELFKNKGKKQTATFILRGLGHRMDDLLPKHYGIREFKFNGRLWNRIIIGFPEEGLGNELRCLTVSEYSWFVSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB61</accession>
    <name>A0AAV4YB61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein KIAA1109</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Kiaa1109</name>
        <name evidence="3" type="ORF">CEXT_338132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001637">
        <property type="protein sequence ID" value="GIZ03704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048488">
        <property type="term" value="P:synaptic vesicle endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033616">
        <property type="entry name" value="BLTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056742">
        <property type="entry name" value="BLTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31640:SF1">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31640">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN KIAA1109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25040">
        <property type="entry name" value="BLTP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01220">
        <property type="entry name" value="FSA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Bridge-like lipid transfer protein family member 1 C-terminal" evidence="2">
        <location>
            <begin position="114"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ03704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="655" mass="73409" checksum="21A9B7847EBF63D3" modified="2024-11-27" version="1">MSPSLSKADYLAFSSPMNVQSSSSGVATSVASDSIPLSTTFTKTSHALKNIITCETIKESSKPLRPLISNHGHRDRLWLNLDRTVQESKKGVDLRSPSKSGSSSYDESRDSISSEQSSPLHPGRPSSSWETLVLFAVNLSRLNVHMNMGNVKGNTTKGGIVGGTIELSRIDTCMHLKEDWGQEPDHTVALKLGALESRLDYMGTSVLMGRVSSLDITLKDEWRVSTVLNQDHISSHPTKRPALIFVNGELSWDQLQLLISKSTTPDLIKMYSKLEEFFSQQFHSSKRVFSSLQPRLQRHSLKNRSRKSKSSEETEAKHHRHWQKVLSMISGLQLSTMASALPDMGTILGGTMDLHGYNISLACFHGINFRSKAWAIFSMRKPTISFATEAQDVVKDDGTVATHIVQNLSYALGSSSTETAQHASMATVCRISRNVLFPPQFRSMHEWFHYAFATSELDDVGRFPVLEHDRENINDRRVSMPSKGPEFNHNMEVIFALPSPKPTVDCSFVTEFDDHIFVAVDAEAFFFLHDLITSYIKEKEISTFGKSHSPDSDRKLKMADPTDSLQKDWRSYQCHTWHLEPTVRLLSWAGKGIEPYGVDYILQKLGFAHARVTIPKWMQRGCMDPLDKILAVVMEKMISAVKDDKDDGVTSVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFJ9</accession>
    <name>A0AAV4YFJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_789781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019194">
        <property type="protein sequence ID" value="GIZ05034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13536" checksum="A37F743E6A919321" modified="2024-11-27" version="1">MEIVSKVSSIEIMSGSRFVPVGAFGQKKIGYKKGCPRFLVPGRIHDFSEREKMFLFVEAERIYRRQNFSILFCPSDSVFRREKISCDCRIERPGVSGQGILFCCTKILMKLIIPTFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MI27</accession>
    <name>A0AAV4MI27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_2851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019815">
        <property type="protein sequence ID" value="GIX72028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MI27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9376" checksum="2F16187D79CD890E" modified="2024-11-27" version="1" fragment="single">NANLANLVASIDYEFFHEIEVMFLGITHYSINKYSKGSLLANKLLCKLLIQWSTELIFYKNIFAGRATCLSNLFSLQLAQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX76</accession>
    <name>A0AAV4MX76_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NWD2 C-terminal beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_506651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020212">
        <property type="protein sequence ID" value="GIX75971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056534">
        <property type="entry name" value="Beta-prop_NWD2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23586">
        <property type="entry name" value="Beta-prop_NWD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="NWD2 C-terminal beta-propeller" evidence="2">
        <location>
            <begin position="35"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX75971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12722" checksum="C111931E55BA6BE1" modified="2024-11-27" version="1">MKIKSLFIEDFNGIVSSSIDKTIKVWNVKNIFEKVYTIDRMEMAIEAVLLSGDDELAVTVTRSSVGVWSVSTGKLWSKLVDSPVGAIVTHAVITTDSRYVISSESGNLLVWNIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYQ3</accession>
    <name>A0AAV4MYQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020229">
        <property type="protein sequence ID" value="GIX76124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17585" checksum="FC9BD0A09FAC1FF5" modified="2024-11-27" version="1">MGSAFHLSDALAKNDKERDRANDWEKAVLKDLSVQFAGFVSLRADLFLNILNIRDFHREGTSQSERDRHFIYLTPWRRMTKIKAGLTTKKRFYRQGTSQSEWDRHFIYLTPWRRMTKSETGLMTGKRVCKKSPDTAFVISPLVLVCLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZV9</accession>
    <name>A0AAV4MZV9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CEXT_75081</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in transcriptional regulation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020378">
        <property type="protein sequence ID" value="GIX78052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048598">
        <property type="term" value="P:embryonic morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000176">
        <property type="entry name" value="zinc finger protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000585">
        <property type="entry name" value="zinc finger protein 784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="253"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX78052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="36378" checksum="D846949BEE8BD234" modified="2024-11-27" version="1">MERNESLGIEACEREHLWRIENFKIFLANNLYFCIPSKEIPVKVLCLSSLPDCLQRMEDNFDCVEHFQSENTLPVFETLLPVFITVAAWTQEEPNLQTDKETQTEAITGYVCNECKACFSSPEALSRHQRKHPRQKEKLKHKCPYCAYLASCEALLNRHLLTHTGDKPHACKQCGKRFSLESHFRQHLLVHTGEKKHECGTCGKRFAQESNLRTHERVHSRERPYRCSECGKDFSVASNMKRHLRIHTIEKDYPCPNCEQSFIDSSHLTNHIASVHTKEFPHNCSYCQKGFRSPGELKKHIEKKHKEEVPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0K7</accession>
    <name>A0AAV4N0K7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_493851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002788">
        <property type="protein sequence ID" value="GIX77775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="6907" checksum="CF2D97A8D3341866" modified="2024-11-27" version="1">MNVGKVRPEAFPSDAMGMASAVVTEHNKSLVKIESDTAGLKAVGYDPPYRAGGCLASFDPNCLSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3W0</accession>
    <name>A0AAV4N3W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proliferation-associated protein 2G4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Pa2g4</name>
        <name evidence="2" type="ORF">CEXT_182271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020419">
        <property type="protein sequence ID" value="GIX78515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7890" checksum="DC776E5C6FB12513" modified="2024-11-27" version="1">MADREELGEPTIAQDLVVTKYKMAGEMVNRVLNQLVEKCKPGTCVTSICETGDQLLFEEIGKVFKKEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N433</accession>
    <name>A0AAV4N433_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_51441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002952">
        <property type="protein sequence ID" value="GIX79567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N433"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9474" checksum="E90E81A85B94CC87" modified="2024-11-27" version="1">MGESSMDTWPSSALEQSSGHHKMTGAWSRAGAQTWKVTCPISNFFPLSLPLHPHLLLFGSDHPPYLASFSPVKRCYSEINSVISLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7M3</accession>
    <name>A0AAV4N7M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GLIPR2_0</name>
        <name evidence="2" type="ORF">CEXT_794781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020600">
        <property type="protein sequence ID" value="GIX80521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="25"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="202" mass="23057" checksum="EDACE949C43168E1" modified="2024-11-27" version="1">MESTEEGDDSCFLPPANSVSLDVEDFRRRMVMAHNGYRELHGSPKLTPLPELEDGAQIWAETIAAKGYLQYCEKLHNIGENLSSIELLSSVPTAERIVHNWYMEIKNFSFAEPRWRRGAFHFTQLVWRNTSHIGIGIAPVPGEPRLFIVVRYFPSGNSNFPGEFERNVRPRISKGSTGSLDEASFLRTYSRTRSLIFEDAYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N931</accession>
    <name>A0AAV4N931_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_371171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020637">
        <property type="protein sequence ID" value="GIX80963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N931"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13617" checksum="4426C9E3B34C26B8" modified="2024-11-27" version="1">MKKSRAEIKIQITARFFVQRHADVAVGLSSLEKHSVKPLRFSETLQLIGRLYRDTQNCLFRHLHRRHGCANVLATMVTEGQQYEGSRRPRLTNARQDRMMYDRPKLSQPHHLQLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDH8</accession>
    <name>A0AAV4NDH8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_10245_1</name>
        <name evidence="2" type="ORF">CEXT_509831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020815">
        <property type="protein sequence ID" value="GIX82817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDH8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="674" mass="76273" checksum="4B18A7AB66FDD7F1" modified="2024-11-27" version="1">MPPEPPVQGHRYTQSQPGVTSQRFQAPGYPNNNNNNRFESQISHESHRSINSNQRTPVIIPPNFNKEEDEEEDDQDQSSSQNIENTQLQSILPKEKVPQRDLIIDDELRVIHTVEENPLNKTGTVKKYWDFRQENSGLASGQIITVPALQNSNVLPVSILGDNVQNHKIAESVASSTINENLHSKIQVPDVFKDATHTVKTEVLLSEPEEKSIKYQNGSKEFYHIDNKPKVNFESVVDLPPHIMNIETSSVEQNNLKVVSTPETIPNGNFQRDIPKYAINNSNKPDYTRDSSIPQNHKKTLTTDPLLQWNQEIKYIPAEIFRKNSTMSIENNYNDNYNSKDFVSEHSSAPFGINVRNKAQYQQFEDTTKSNEYPIELDDESSETEPKILGYLVQLQLCHREHLLETWLKTITSPCIRRKNIKCLAPCQQSFGRRNNSRLLYPTLSSTTEKPETKRLKFTYASLPRTTTERTSDAFITNGSKRFFNFRTGTTHSVPGITASPVSKSVLDVSKSTESLITDASSEIMGTRSSQSRENLALILIQVEQWSRANARRNQIRIVSATSENEANIQPNTEVLTTEYSTESIIGTTLDEYVNHTETDLTEVVTESGKQHYVTKSPTLSYPTNNTIIDEVTTELINREQIIIDSLKSTKIKNAGHDVQRSSTLDAHGDGSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDX6</accession>
    <name>A0AAV4NDX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gag-Pol polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pol_4146</name>
        <name evidence="1" type="ORF">CEXT_509431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003179">
        <property type="protein sequence ID" value="GIX81881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25759" checksum="6F25CFE521DE397C" modified="2024-11-27" version="1">MILDPGRGLWYFSESSRINRNYRTHHPKLILFSFEKHRSGLQMVLERDTESQFPDLILQQVCFTLNISQTLIPVYFPKRIQCNAKTDSLAILLSDEHDDWHSKLPVIRFAMNTAVFKTMERTPTFQQFGRSMVELWIKPSKISSKVWVTLHFISKLKTKRLMPKRDGPYLISTLKLPTSHSIAHFDKPSDPIVTYHNSAPISFRYQFSSFRKRARHNFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDY3</accession>
    <name>A0AAV4NDY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_251551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020824">
        <property type="protein sequence ID" value="GIX82982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="6996" checksum="8DB4789416A2D48B" modified="2024-11-27" version="1">MKNASPSPKSQYEVWEVERVVMFGRLVGGQCVKAVPSVQLGTLPLGIISGDWPVRLGSGVGVDIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGE9</accession>
    <name>A0AAV4NGE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_309661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020867">
        <property type="protein sequence ID" value="GIX83434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14985" checksum="8E0245FE45520228" modified="2024-11-27" version="1">MTYRESLVSTVKISLRDLFKMQLPFNGQFPFFCYSCKNWGNRKGVQRRSFSCTLAGADRSVGAAPRISGRLLRALCQIEARQHILQEPSSLHTFCGPFFACCNNHSSISILIAKDSIFMWTKNGYDPYDTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIH4</accession>
    <name>A0AAV4NIH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ankyrin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ANK1_3</name>
        <name evidence="13" type="ORF">CEXT_741651</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003442">
        <property type="protein sequence ID" value="GIX84602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="11" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="230"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="263"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="297"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="331"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="446"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="479"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX84602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="514" mass="56405" checksum="BD81F57F4C44C20E" modified="2024-11-27" version="1">MPKNQLPIHVLCHRGRGSASATLSMLLRSGGKDMRLIKDKDGKIPLLIAAENDNNSLCRELLTALSKEQLKFRTVEEGNTVMHIATQRKMENCFGYFLTDEGLTPLHMACENGDLEILKVFFQFRANANITDNQDRTPLHIAAEKGFSAIVEMLADKFKASIFKRTKDGRTLMHIASESGHQETALVFLKRVFRFICQIRGTIALNANAFNHIQEVLNKGKNNLSMEKNTGTKAIHTAAAHGFVEVIRNLLERGENVDATTPENFTALHLAVQANQPEVVEILLGHGANVQLKAGKNGETALHMAAGVIDGHKCAELIIKSGADVNARNEDGETPLHNAARQGQLKTVTQLLEDGAGLDSLSKNGETATHYASSIHKEQIHYPTEDKDLIALMLQNGGSVTTETQKNNETAIHYVCRVGNEDILKEIIARLPQSKLQIACNKQAANGWSPLLYACDSGKSLVVQLLLQNGARVDVFDIEGRAGLHLAAEHGHADVIDILLNHKAFVNVRTKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKW2</accession>
    <name>A0AAV4NKW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_606911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003429">
        <property type="protein sequence ID" value="GIX84468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX84468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="475" mass="53231" checksum="36EF3B483A0DC48C" modified="2024-11-27" version="1">MFPNSDNDTSQRPVVLVDFLLEIACFLVTICGMLFTVYLYDMKNCFYVVLVNTVVEVFLFCALLWSRRHFYFEITENVIEPLLFSQPPQEATTNYQLLEEELSETSSVQRFRELIETSSFRQRAPLDYSLVPETSMKQPAAVCSSMKQPAAVCSSMKQPAAVCSSMKQPAAVCSSMKQPAAVCSSMKQPTAVCSSMKQPAAVCSSMTQCSSISERDFQIAVAKTISQNPLDYSNKSRQRAVPQAAKQMAESDTRGRGNQQQTSVPRKFTRHEFVNDSFQIDDDEKLGVRKEQKDAANSNTRMDTSVTSQEHSTSHTTLLQQRMTVERCISVQNPVYQCGTSPIDMFQHAMSNENQNVVNSGNILRRETQIQSNPSAGESNTNADPQRRITQNIPVNSQQRVLSIHAVEMMSRLDGSAETLHDAIATCHNLSPNEWTTVWNFARKGYSPETIASILGLRLTDETIDEYTESEEMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ46</accession>
    <name>A0AAV4NQ46_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_758971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021046">
        <property type="protein sequence ID" value="GIX85302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX85302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="420" mass="48227" checksum="1ECA88A10A94526C" modified="2024-11-27" version="1">MNAKVLKVYVNVLMMVGLIFIFCLTTIETMITEDASRNVLKETSKQLPWLINPQKSIILANRVINNDLKPENIKGTILPSLFNVNIIEKLFKSNHENLNLGQDEKQQKLSEKSHQKRDFLSVYNKTCTGNETESSKVNLDSDSELDSTTTTKDSDKSRFKRNTFISSPKYLLSESRFKRSLGLETMNKPMSAELFIRNNYPFNSNNKRGIVYNSKEKQHFPSLSDSTQIAKAHKTGNFVITSNALNNFQEDDKPLPKISQSFTTNRTLSHEKLLEKFQDLNMGVDGRFSSQSLNENHDIPRNDTISKFWWKKLPIKINLKNNDNQFTNISNSNSLTKLGNMKSLCNCKEEDFDMNTSGMQVANMMKGNDHLENERHTGKAFTTEDVNTNQKEDNILRTIQINSEYNAENKFPMSQETPYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRF2</accession>
    <name>A0AAV4NRF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helitron_like_N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_27374_1</name>
        <name evidence="2" type="ORF">CEXT_522871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021194">
        <property type="protein sequence ID" value="GIX87004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13213" checksum="83BCE69FF027774A" modified="2024-11-27" version="1">MIRCGQDNVILRCPELCQQFMVDMYVKIESERLRYLRHNPQKLRAEEYIHLRDAIANNADTAEIGNSVILPSSYIGSPRHMHEYIQDAMAFVREYGRPCFSSRLHFCIRFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRK0</accession>
    <name>A0AAV4NRK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_153721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003541">
        <property type="protein sequence ID" value="GIX85752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043977477" evidence="1">
        <location>
            <begin position="24"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14569" checksum="99CF6315A447D863" modified="2024-11-27" version="1">MDSSRRSIFLLIIFSSTLYFCQAQNVTLSDLNATENSNVIFETILPEVSSTSFQDETTISEIITQPLNTEVTTISEIITQPPSTEVTTISEIITQTSSTEVTTTSVETSSLSILQKWQTFEKLSKVFAKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTG1</accession>
    <name>A0AAV4NTG1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Exonuclease 3'-5' domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">EXD2</name>
        <name evidence="16" type="ORF">CEXT_108711</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the EXD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003741">
        <property type="protein sequence ID" value="GIX88157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000041">
        <property type="entry name" value="Exonuclease 3'-5' domain containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="15">
        <location>
            <begin position="41"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00061005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00069878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIX88157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="558" mass="64672" checksum="68F8C3192D64AF7E" modified="2024-11-27" version="1">MSVWKKYPVKYIALASAMGFFAYKFVISKYYNFGRAKYIVIESIEDWNMHETEIIKMFNKSKVIGLDCEWVTIDEERKPVSLLQLANDSGFCVLVRLSCLPVWLMPPALNNLLFDETILKVGVGVSEDANKLFNDYCLEVHGFVDLRYLVKDIKEIQGKSMSLKSLGRELLGIDLNKSKELRCSYWDTSHLSNEQIQYAADDAIIAAKIFTEIQKRNTNFILGNKTKFLKEIIPYIDVPFKQVFINSSKKSDGLPTLKKPYKTRYSKPRQRPMYDNCQLVAPDGELLCSCDKGKAEWYIYKGLGEKISDDPFTVRLNFEPSGRPTLDNVFYTKEKSNQCVVCGKTENFHRKLVVPSEYRKYFPNLMKKNLSHDVLLLCVHCHKKSNMLDQLMRQKLAKMCDAPLGCKKNVKFKFNPELARVKSAATALKTNGNKIPEWRQQELKKVISDYYEVPLVTDEILDEALNIEVSAINNSFISHGLKVYQYFCENDGLIQFEKMWRQHFLDTMKPQFLPAMWSVEHNHKRLAIQVINHEREVDFEESILGLTPELVDEIKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVU6</accession>
    <name>A0AAV4NVU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_391311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003708">
        <property type="protein sequence ID" value="GIX87764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="20788" checksum="5E03EF23FA20339F" modified="2024-11-27" version="1">METDCRSLTRRKCSEKGDRLHNADAKEVCSKRSQMADSERSRQTPEKEQGCSEKRLKGVVINETRRVLKKEKRKCSVKLDRTQRRRKCSVKLDRIQRRRKCSVKLDRIQRRSKCAVKRERFRKVKRDRLGDRETHRKCALKKIQISEDNHIQSEQWKETECRRKTHIKRAVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4U2</accession>
    <name>A0AAV4P4U2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_69321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021671">
        <property type="protein sequence ID" value="GIX92242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4U2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10589" checksum="EED5B3EF651EAD9C" modified="2024-11-27" version="1">MIFFPPTPCLIYCQEEEPEVSHFEFYPYLPFVISSLQLHKSARCLKQPIKPDHRPIRPSSYKSPPATLLIFKREPPTQIGAKPYQMVTNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5H4</accession>
    <name>A0AAV4P5H4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_741241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021611">
        <property type="protein sequence ID" value="GIX91748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5H4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="10003" checksum="B049AE728EDCDE54" modified="2024-11-27" version="1">MRYVAYFVSEGPNKDRKAVTKCKVRDHKVMCETIYECNLMFDFPVRKPPLFISLWKNFRWVFLNALIRFFLCRKQDGHEIIPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCK1</accession>
    <name>A0AAV4PCK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_542061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004449">
        <property type="protein sequence ID" value="GIX94915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="46" mass="5059" checksum="D631903EF384A4B7" modified="2024-11-27" version="1" fragment="single">MVFQSAVRTHSGGGELRRGLNAGASQIARKLQSLMTDRRYNLPEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PEX8</accession>
    <name>A0AAV4PEX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_677631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004547">
        <property type="protein sequence ID" value="GIX95649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PEX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10108" checksum="1BC9AB3BA2D73984" modified="2024-11-27" version="1">MAISVPNPRRRFLHSEIPVTQCTPIRTTRPQGVRQSHANLQMTWRLSTPPGKSFAISLWTKSTGRPLNSSRKKHPPSPTQVVNPKTAVGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKA2</accession>
    <name>A0AAV4PKA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004662">
        <property type="protein sequence ID" value="GIX96561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="228" mass="25821" checksum="93B7A3F01E58C853" modified="2024-11-27" version="1">MKFSRQGKLIFTTADPVCAAQILNLDKIQDTPVSTGVTFENITERFLVFDIPTHLQLSELADEIMNNNDMEVVEVRQCLHCYDFTHATRVCDKKICPLCGANHEGQCQGPEKCILCNGPHSATSNICPRLTLEQKILEFKCRNHLTIGEARRLYAHSSKTNYSEAAKINSAAPNIEEIVNQRVESIVQNITIKMEQQTTLLIEIFQKTIENLVQYLVSVFHQTDLKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLS0</accession>
    <name>A0AAV4PLS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_448831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004795">
        <property type="protein sequence ID" value="GIX97579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9308" checksum="6E4ADBF23065FFE7" modified="2024-11-27" version="1">MKIRYYTTSANARNNLCQRRKRTKKNSPILQYNRFSSSKIMEIHSDAPVVLLAPEFPPLLEILIFPVSARRSANELWKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9M8</accession>
    <name>A0AAV4Q9M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_564911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005745">
        <property type="protein sequence ID" value="GIY04715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043741578" evidence="1">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15234" checksum="FD065B2C669465C7" modified="2024-11-27" version="1">MAKLTCFLVLLVAVILCAEAILIDPEPMPSSGSDNIPNLRERDRKCKTNGVYSTQTIAPCTSKCVNGIGQDVHCPESFKFDTFQHCTPDRRQTAEEGSSVHHYKLDVFKAEDMGWCDLVDNEFIDEDLDWYDLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9T3</accession>
    <name>A0AAV4Q9T3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_607941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005838">
        <property type="protein sequence ID" value="GIY05399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9T3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12159" checksum="6B7DFC6A3009FB28" modified="2024-11-27" version="1">MPLSSAKSIFLVSFYLTFPPIKIPINLQANQTAKPLILLNNLGFVKRKKRESFTIHNSKILRAQNVSFLSTLSEIRLLRILAYGSSLCIILLTGNSVCEVHFGALWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT29</accession>
    <name>A0AAV4QT29_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="9">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ERCC2</name>
        <name evidence="12" type="ORF">CEXT_740651</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="9"/>
    <dbReference type="EMBL" id="BPLR01006627">
        <property type="protein sequence ID" value="GIY11262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY11262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="26971" checksum="3251F3133AA6A3A2" modified="2024-11-27" version="1" fragment="single">VLQELRRLLNYIEEQTGQVNKITGLCLSSEKNLCCHPEVSKEKDGRIVDGRCFALTASHKRSMAAVDPSVDICAYFEVSFFEKHGREFTLPAGVYDLDDLKNYGKKNGWCPYFLARHAITHATIVVYSYHYLLDPKIADLVSKEMSKSSVVVFDEAHNIDSVCIESMSVDITRRTIERSQNGIQILERTVDKIKDTDAKKLQEEYQRMVEGLREAGIARQTDIILSNPVLPDEILKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYS4</accession>
    <name>A0AAV4QYS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_682791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007030">
        <property type="protein sequence ID" value="GIY13996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9210" checksum="45BF0AD0337EEE51" modified="2024-11-27" version="1">MAEIQTGVRNCLTAGEEKEFQWSKTLTAHKGTCDNIYKGREKSELIQMSFEMFRVQKKPTLTSKRFAAKELTCLLGRDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZR0</accession>
    <name>A0AAV4QZR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sod_Cu domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_116806_1</name>
        <name evidence="4" type="ORF">CEXT_581161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007058">
        <property type="protein sequence ID" value="GIY14311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043808723" evidence="2">
        <location>
            <begin position="24"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="3">
        <location>
            <begin position="335"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY14311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="380" mass="42511" checksum="921E377341980817" modified="2024-11-27" version="1">MMAMRAPLLFVAFLVTLLHCNVAQQVQMPEAGALLLPEEELSAQVQSLQRNVSELWTYIYQLRGAVSQHLNHLRTHQVELEDQMHRMSHYHDGHGEETNAAHTDSHHHSGEQHSHSNEQHSHSGEHHSHGDQHSHSGEHSHSHGNDGHSHGSDDHSHGNDDHSHGNDDHSHGDDGHSHGSHGHYHDSHSHSHSHSHDDHGSHSSHEEGDGHHHHDHKDSHEKEDELQQTQQGADLQQVQTGGPVVEPLIPSSCVAQIFEYDLYEFAVCNVQPNRAIPEDQQQEIVGQVTLWQKKIGGSLNLHVRLRGFEMGDHHGHHQQQQQQTEDNETPVPVSHKHGFHIHSSGDLSDGCQSTGPHYNPKTSNHGGPNAWSGMHLLKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2E4</accession>
    <name>A0AAV4R2E4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_293531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007215">
        <property type="protein sequence ID" value="GIY15226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2E4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="469" mass="53137" checksum="5F866265B03D58E8" modified="2024-11-27" version="1">MSILRIHHSYHPSQNSTPTIKDYNLLPNTPRECLMTDTPEVLALPAKKNLFKTPDCHRLLTNNPLSCSSRRQAFSHQQSEGFEVSRETAHNQFISNEPIPRIKEEKKTLDSYSVNENSTAISSSQKICNISAKRFNDGAIKFDFNLNKNVEIKVNPNTYDVSCLLLPSEQNVPITHGKESTHTQTDELPNKDENIVHQKQMPISKFSFVPVQPSNASTPSSFVSNNINTRSYCYTEKESPLDMESSFGYHISLWMYLLEIPKAFSSFSEVIEDAGSFAEWEENLNCEQSRANEANSTPVKKGHSEVNDESANTVPMPSYCKTLPNYTVAVNEKSVINEDDIKAKNKKSDEIFPETLVDEESNYNSLKLGLFKGDKNKEDICLRPNRIHSPGKDHKELIRFVSEEPCKTNYQSEIALDIQSSYKKSPRQLNKNTDLNHSLEKVSDSTCSELDESELSTGMNFTSVEKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R665</accession>
    <name>A0AAV4R665_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_600751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007472">
        <property type="protein sequence ID" value="GIY17149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R665"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10767" checksum="78A86A8F66A8F61C" modified="2024-11-27" version="1">MCRKGKKKKKNKVSQGRKDRKEVEDWARDDRPDKNRGEGGINSGLEIEVSRTGISGVVRNKKFHFSIVYHIFARGTPAMNFYTLSKTPTQVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7R8</accession>
    <name>A0AAV4R7R8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Homeobox protein cut-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ct_1</name>
        <name evidence="2" type="ORF">CEXT_739171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007366">
        <property type="protein sequence ID" value="GIY16376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="285" mass="31587" checksum="610237DF4D91D090" modified="2024-11-27" version="1">MPYLYSPYRNCSPLSSSGDDMGTLDLSMSSQLRNAINSGVKADTTNGSSTDDRSNSEINDDSNLSQDNLMQGDNSDRDSIDDGQTHNREASPLRPSTSNEQVRPAPGSGSSNRRKPAMPQWVDPGLELSPENTDDEDDGLDDEDRLDDESGNEQEEIINGVCVRQTEDFDLLMSPRVETVHVLPVPAPDERSSTKSHRNRNEKNRRTAVVSPDRSDNEVEGLTNGIGDRDSSETNMKNKLLCARDSATLKNPSSWRNKTMMMTMKVGTMLKQRTGVKISKNFNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R824</accession>
    <name>A0AAV4R824_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_14301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007476">
        <property type="protein sequence ID" value="GIY17174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R824"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8535" checksum="BE83E53D7AD9206F" modified="2024-11-27" version="1">MLVLSHCEKTVEVCPLPSMMHDLPEVLIGANVVIKDSLSKTIGVPEYALFSRAVSIVREEFLRPAFGPQLIREQWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RA38</accession>
    <name>A0AAV4RA38_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_486341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007724">
        <property type="protein sequence ID" value="GIY19178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RA38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7898" checksum="81F60943601DBCE0" modified="2024-11-27" version="1">MNKFLRGSINIEPPPSSHSGAREKQMQVFRIDPVPPALTSRLVPPGSSDLHSKPKFIRFGHFQSIFPLSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAI9</accession>
    <name>A0AAV4RAI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_519661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007497">
        <property type="protein sequence ID" value="GIY17321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13235" checksum="5EB381CAA21BB5F8" modified="2024-11-27" version="1">MAIDSRISSTLRIPITFDWDPLILRTPPERVGEDRCGAEKEDPFECCRRIVWEAMRSHARDLHLRYLMSFFHSLGGRDESFKAFSMKGLGLFVSFLFVWLAWEGCSKMIRCSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCF7</accession>
    <name>A0AAV4RCF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_580131</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007616">
        <property type="protein sequence ID" value="GIY18366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="8" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="9" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY18366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13812" checksum="28703EEBAF152B29" modified="2024-11-27" version="1">MRIGVRIPVLRRDEYWIRLFFFTALHWAAKHGNLDVIKLMAGTHKLDSNARTALKAFQLRLAPCIHSKVEIPNNCAGTVVFRELETKEVWAVRRKGNMPSPVGCPHDANQDPRGLTPAGSISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLB3</accession>
    <name>A0AAV4RLB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_463001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008046">
        <property type="protein sequence ID" value="GIY21661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10202" checksum="29505A1BF29E4CD3" modified="2024-11-27" version="1">MTEKFRHIHDIACRDTFCTKKRRKKDPTYIALDHSEKMAVAYRARDSCSKLLVAHATYQFVLPQISLLMAVPFASAPRWKLGEIPPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQY4</accession>
    <name>A0AAV4RQY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_746651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008248">
        <property type="protein sequence ID" value="GIY23226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="207" mass="23545" checksum="55AD162CB217E860" modified="2024-11-27" version="1">MWSSTIPRNKGLNSAKITKELIRCIIELVIVVQMDYSPIRSELEPYAHDVCVKLSTHIQFSTTNMLLAYLKADFSLKWKRDALPPDNECTTSSKPQAGDNSGRSTFSQMIGSFLHPTVRHLWSSCLLWAQNTATCSLKAKESQSTLPCSKFLFPQQEFAKRLKTRKKNSSCSLDVPPGLPRQQQDEKRDIELEKNKQTKVPNSKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQY9</accession>
    <name>A0AAV4RQY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_262051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008360">
        <property type="protein sequence ID" value="GIY24150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17069" checksum="33D069D3BFE2E201" modified="2024-11-27" version="1">MFAKIAFFCAAPRSCQCLCTSRQHWSQYLIQTTRWPDEWTTSLTDMIPCHRQDHTHTQRTRNRCQRPSSSSHCQSLCRPVAPVVNHIAPSCPVAVRRRRRPSSFGAGALGLGHGAALGLGYGAGAPIGLKVLDSAMEPPLCGYGAGIYGAELAKAIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RT14</accession>
    <name>A0AAV4RT14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_645131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008350">
        <property type="protein sequence ID" value="GIY24091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RT14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12524" checksum="37B94D9161B66A5D" modified="2024-11-27" version="1">MLSNDFNERSRTSIQTPAIVCRTPPPLPSNEKFHLQKRCMAAGLNRVINRAGGNVLDAASIRSEDFALFSQKVLNKILKITVECRRINDLLDEGSGKSVCTQRRIVWRNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYH6</accession>
    <name>A0AAV4RYH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TRPL translocation defect protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Ttd14</name>
        <name evidence="1" type="ORF">CEXT_561671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008606">
        <property type="protein sequence ID" value="GIY25936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070300">
        <property type="term" value="F:phosphatidic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045494">
        <property type="term" value="P:photoreceptor cell maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053227">
        <property type="entry name" value="TRPL-trafficking_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932:SF1">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="16138" checksum="BF0924048A0C8C86" modified="2024-11-27" version="1">MHTQRRRDVDTQVIEVKRQITHRDYINMLSQRDEKHYRVLKLRRCFMLNNMYMQMDIYKGPCHPRCEGLILLETYTTLKGNELIGRLPSFLNVTKEVTGNPSFSMFNLSFKTEWTPSKLRSENNCIDGAYTTIIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYM7</accession>
    <name>A0AAV4RYM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_678761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008689">
        <property type="protein sequence ID" value="GIY26482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16603" checksum="68F787DBDF7AC714" modified="2024-11-27" version="1">MSLWKKVSTEFLRSRSACKKRSELRNQLFYLAPPPKKASLSAFQPIKSRRCREKQHKFHPLSSFLIFPTEGTLVHLNAVKVHFAEEHASIFLGKKVKHPIDHASRWSYREPSSPSEAEPAPPCPPCPPSPPSHQCLSVRYTSSKCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1K2</accession>
    <name>A0AAV4S1K2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rap-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RALGAPA1</name>
        <name evidence="4" type="ORF">CEXT_291451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008864">
        <property type="protein sequence ID" value="GIY27859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1K2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF11">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN CG5521-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="3">
        <location>
            <begin position="619"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="814"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY27859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="848" mass="93277" checksum="1306D44476E89B40" modified="2024-11-27" version="1">MLIVRRHDILLLREYTAHFYYALHYGLMANDQDIINTIVKHCGPNFFSIGLPGSTLLIMDFIYAADTVISSSDIKRKFPEVACWQVPRTEAMSILGALLCLTNVYKEIPTLQPSSTELFTIACKDAKDHITSILFKAGKREPAGLARCIAVNSIGIYLYEELMNKTNHYRIKEAVTVLLIAVRSSISPSANKPRTKEFNCKAVARVASDMLLLLCDHAEELRKNHSDSLEQFLASTLENLLPNSDAAIAEEDKKVGSPSVSEQDFVPLLSVFKVLNAAASGRKLDAPQGTQSLTELSTPDVRPQCTGGKFPGGYHPNPICASKITPELAAKSLMYHLINHLGHFPMGVGPSRMTSLVNEHDDVPNLTGDELSAEVFHAPNVQFFVLNSNSIVSFVEIPALDMPGGGATAGLTTSKSQVRIIIRDLGGKFSWDCSILYGPPDLYFSSPDMDPFSAPPSLDISQTLQPTSSLNKDGSILLSSQGLRHRPKDMLPTVENSADDLDNLDDLLQYIGYTSSECVINPGQPLNSTSHLQNEDGHQKEVEMIELILNQRNQEYSQSKKFSLNSCMEAKGVQSPNPADANSQFQHCRLLLNQMGFTSWERRSQFDLLKKNEQLLRELRNLDKQVCRDTHKIAVIYVAIGQEDKNSILSNLGASLEFEEFVAGLGWEVELENHPGFLGGLQRNKSTGDTAPYYATPFTEIPFFGPLFNGAIVGHKVLPGLVRATAINANRAKRSLISLYMNYFEERHKSLETIVQNHKDQTTFEQFAASVYSPAPSKTYAASRSSGPPSRADSSCSKGIPNLAAALLDAHSKGSAYSPSMRSRTVSQSTAEDVSPPQLGHRCLYEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4A5</accession>
    <name>A0AAV4S4A5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_275771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008851">
        <property type="protein sequence ID" value="GIY27774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4A5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16375" checksum="6F428CC45A0BBA5D" modified="2024-11-27" version="1">MGRRNRNAQKMTAPSPWRKVSAIRKTPTIIPPLRNNNDTLITSPPDKAGLIADTWEQQFKLNDIHLNDATKHTLEPTSPEMLSNLTDEEQCARISRILMKKDIAQSLLDTFNATTFGLALDEDDRVKLKTLEQDLINALREVGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9L8</accession>
    <name>A0AAV4S9L8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_135741_1</name>
        <name evidence="3" type="ORF">CEXT_710481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009147">
        <property type="protein sequence ID" value="GIY29866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349240" evidence="2">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY29866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="21489" checksum="E30D635ABCD3912D" modified="2024-11-27" version="1">MVALLYCVLCQCCTSALANITQEILQLKPKQFSPHKQLDILRRKAKIDDILGKLQNIFSLPIFFLIAGNFLTCGSVIGKHLNYGTQQYRSYHIKESSFYGISSFCCLTATLWVAGGVSNQFQKLKEAFHKKEKLRLLNVTSLDEPTLKKGYFEETDFVFTGCDIIFYKRSTILTLFGALLTYTVLAVSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9Z6</accession>
    <name>A0AAV4S9Z6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cuticle protein 16.8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_780161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009129">
        <property type="protein sequence ID" value="GIY29784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043416633" description="Cuticle protein 16.8" evidence="3">
        <location>
            <begin position="16"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY29784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="18547" checksum="BD2A6A6A56E63EA3" modified="2024-11-27" version="1">MFILAVFSCIALAQAQLYHDNHDHHHHHHAQPYKFGYSVKDHHGEQHREESGNGAGGVVGSYGFTDARGIARQVNYVADHAGFRAQVKTNEPGTANQNPAAVHLISNAPYAHSGGVALSMEGLDMEDMVLDMEDMVLDMEEMVLEMEDMVVLDVDTMAMAMEVLLDTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SCA1</accession>
    <name>A0AAV4SCA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_343081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009425">
        <property type="protein sequence ID" value="GIY31800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SCA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="18926" checksum="B570060BFF539C41" modified="2024-11-27" version="1">MENKEGREAPIATSETDCRIKSSLCNSLKWWPLVMIFFPLSLSAFLGATEYPRFPDHPSRGDDCAEAILVDRFGNCVAHKHNKMVGESLERMYSFYSDVACNKLADETRGGSANTKPLDLYGVAGAFMDVVFRCCSFHPAWTGCDEFLLNSQQALWRWQNAVSCSHTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGC9</accession>
    <name>A0AAV4SGC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_61111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009586">
        <property type="protein sequence ID" value="GIY33049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9571" checksum="B28705ECAD5BA102" modified="2024-11-27" version="1">MEVNLLRECPLRRMARRLEGMQFHPAIISYYVLRRARTPVVKSVVAAAIIVYFCIQFYSSCEFRCEFNPLAGIESNGVAVGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIM3</accession>
    <name>A0AAV4SIM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone H1E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_25181</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009666">
        <property type="protein sequence ID" value="GIY33640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000140">
        <property type="entry name" value="Histone H1.0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF20">
        <property type="entry name" value="H15 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="9">
        <location>
            <begin position="34"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY33640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="12426" checksum="6DFFADA877392A8C" modified="2024-11-27" version="1">MAEETAVVASAPIAATPKKKAKNATGKPKNAPPSHPKVSEMVVTAIISLKERGGSSLQAIKKHIASQHKVDMDRLTPFIRKFLKSAVAGGTLVQTKGKGANGSFKLNASGPKAKEPKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJR6</accession>
    <name>A0AAV4SJR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_679321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009796">
        <property type="protein sequence ID" value="GIY34673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13032" checksum="71B31488EC60890D" modified="2024-11-27" version="1">MLLNTLKFFHPPPSPKRRLMKHARRKGVLSGTRKSIVSSLHSLPNSTGKRVLSWNDHCLIVVAVPERKGGMLSANKEKGQTSGTKEGPWDCLWREVKETGVIRRGILGGCLHRISLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMT3</accession>
    <name>A0AAV4SMT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol 4-kinase alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Pi4ka_1</name>
        <name evidence="2" type="ORF">CEXT_378201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009851">
        <property type="protein sequence ID" value="GIY35065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY35065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9832" checksum="C8DCD96992DEDF9B" modified="2024-11-27" version="1">MAGVSSKEFYFNAVQLLARSLASLRPAPWEKVNHLLNMCPQESAQGIFKFDQRGQDAVFALGIFFCNLISSEFFDVFLVVYYISNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQ70</accession>
    <name>A0AAV4SQ70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_679081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009939">
        <property type="protein sequence ID" value="GIY35602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQ70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY35602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11016" checksum="05ACFAB8EA7B6CA3" modified="2024-11-27" version="1">MATDLHILSHRISYEEPAHCKMSSWVMSAFLLTVLVSAFWMAPVESVDCKRLCELSGAPRIGDCYCKIILFGSKRNSDSPSNSETVLTCDELCERSGAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWK4</accession>
    <name>A0AAV4SWK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">EH domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">EHD3</name>
        <name evidence="14" type="ORF">CEXT_619461</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010096">
        <property type="protein sequence ID" value="GIY36842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09913">
        <property type="entry name" value="EHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000147">
        <property type="entry name" value="EH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000038">
        <property type="entry name" value="EH domain-containing protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040990">
        <property type="entry name" value="DUF5600"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031692">
        <property type="entry name" value="EHD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF31">
        <property type="entry name" value="AT21416P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18150">
        <property type="entry name" value="DUF5600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16880">
        <property type="entry name" value="EHD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="13">
        <location>
            <begin position="54"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="11">
        <location>
            <begin position="445"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="477"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY36842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="532" mass="60788" checksum="8E2F6F1F99BBED28" modified="2024-11-27" version="1">MFSYLTKDSRRHQPDLYNNVVEGLKKIYKLKILPLEEYYAFHEFHSPPLNDADFEAKPMILLVGQYSTGKTTFIKYLLEKDFPGIRIGPEPTTDRFIAVMHGEQESIIPGNALVVDPKRQFRPLSKFGNAFLNRFQSSVVNSEVLKSITIIDTPGILSGEKQRVDRGYEFTGVLEWFAERVDRIILLFDAHKLDISDEFRRSIEALRGHDDKIRIVLNKADMIDSQQLMRVYGALMWSLGKVLNTPEVARVYIGSFWDQPLNFDTNRKLFEAEEQDMFRDIQSLPKNAALRKLNDLIKRARLAKVHAYIISSLKNQMPSVFGKEAKKKELVKKLGNIYAELQKEHQIPLGDFPDIKLMQEKLLQQDFDKFNTLRPKLLENVDIMLRDDISKIMEMIPREQEDQNIDTAPVQGGALNALTDNPFGHGRGEGADAGSLQTDWVVEKDRFKFDAVFTRLNPIDGKITGAAAKSEMVKSKLPNTVLGKIWKLSDIDKDGQLDADEFALAMHLINVKLEGHELPQELPDHLIPPSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY65</accession>
    <name>A0AAV4SY65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_551691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010173">
        <property type="protein sequence ID" value="GIY37487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12605" checksum="177DF05E6DA4E561" modified="2024-11-27" version="1">MSHSEKFSSTIPPSLDGLVNSTECGHQLNFLNQALKVKKECAGLRSECFCNQRRCKSLSVSFGTFSPSEQQLDFNCVALLVSCGNKNHFSRIWMAKASFWFSKVNVPDNAHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYR3</accession>
    <name>A0AAV4TYR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_687651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011960">
        <property type="protein sequence ID" value="GIY50297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="16464" checksum="68B9F9FB7B80B4B1" modified="2024-11-27" version="1">MPPEKRTVLRGSCTSRKTETSRCREREESEGESENSSIQEEAAYLTLAEKEGGVPKVGHHCPNEPAIWSDPTNCPRVVGWTDKAATCCMAFSESRQFIHTPCFPSLHAAVLFSLVVGWGLRGCPSEVSLVPSPMAGNMCAWTSPGQQHTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U842</accession>
    <name>A0AAV4U842_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_135041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012435">
        <property type="protein sequence ID" value="GIY53936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U842"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12657" checksum="27591030F6EA86E6" modified="2024-11-27" version="1">MFFSPPPSHGCFCDLSFAFSFRPPLSVTSLPRNHRRRRNFRSKTTTDRRSEFESLCKLISLEVLTLKRQFSLSSFNGGFHFFEKIFQEKLNQLKKLTKYVCSYAFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U901</accession>
    <name>A0AAV4U901_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_739771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012471">
        <property type="protein sequence ID" value="GIY54105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U901"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13403" checksum="43E35C3C1292862B" modified="2024-11-27" version="1">MTGELDNCTGNARMHLCIKWAKGTENVFAENPADLHIYACFQPVLEMRFFAGFRLLAPCGALHAILLHFKHIIIWVHVLGIYGILFYFKNGFVFWISVAVVHSSASCSCGVFLTLSPKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBL9</accession>
    <name>A0AAV4UBL9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">EPHB2</name>
        <name evidence="20" type="ORF">CEXT_373121</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01012612">
        <property type="protein sequence ID" value="GIY55179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005005">
        <property type="term" value="F:transmembrane-ephrin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10319">
        <property type="entry name" value="EphR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000089">
        <property type="entry name" value="Eph receptor tyrosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.10:FF:000001">
        <property type="entry name" value="Ephrin type-A receptor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000143">
        <property type="entry name" value="Ephrin type-B receptor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027936">
        <property type="entry name" value="Eph_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001090">
        <property type="entry name" value="Ephrin_rcpt_lig-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050449">
        <property type="entry name" value="Ephrin_rcpt_TKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46877">
        <property type="entry name" value="EPH RECEPTOR A5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46877:SF14">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14575">
        <property type="entry name" value="EphA2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01404">
        <property type="entry name" value="Ephrin_lbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00615">
        <property type="entry name" value="EPH_lbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51550">
        <property type="entry name" value="EPH_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Eph LBD" evidence="19">
        <location>
            <begin position="37"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="320"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="420"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="623"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="655"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="GIY55179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="792" mass="88688" checksum="61DAAA5CC8948AC9" modified="2024-11-27" version="1">MKIKRNVRGAARKWSYFCDSRSWGRLALIDKLDENQVCVVLLDTTLESSLDWTRYPYGPQSRTPGWVEESFTNFEQGINWRSYVVCDVAYNSVNNWLWTPFIERREANRMYIEVKFSMRDCNLFPGMALSCKETFSLLYYEFDAATKEPPPWEPDSYKLIDRIAADEGRFTSTSEVIINTEVRSVPITKKGVYFAFRDQGACLSLIAIKVYYITCPSVTLNFAYFPERRPPDTNCRPSGRQLDPALGGCKCVAGYEPVDQSCQLCSIGTYKENVGDELCMPCPLHSSATFAGSIECQCDKNYYRSPKDPKSWPCTEPPTKPLNLSETFVDQSSVLLTWLPPKYLGNRNDTFYKVTCDKCGAGVNYVPSQQGFTDTRVTVTGLSPVTTYTFRIYAENGVSSFTASMYSEITITTEASVPSLVSNVRIKSVKSSEIALEWDAPDDPFPDTENYEVRYYQKGHERNGSTATTTKEEIVISNLKEGTVYGFQVRAKTTHGWGDYSKTVFKMTGAKLATEVPIIAGVAVTVVAVIVFIIVIIMLYIRRSSDECNKKQPSDCDTLEYRNGEGKKLVPALVHPPIVPTAWLTTPLFTQCGASRAYIDPHTYEDPNQAVREFTKEIDASHITIESIIGGGEFGDVCKGRLKLQGQTEVTVAIKTLKPSSSDKARMDFLTEASIMGQFDHPNVIYLQGVVTKSNPVMIITEYMENGSLDTFLRANDGKFQVIQLVGMLRGIAAGMQYLAEMNYVHRDLAARNVLVNGNLICKIADFGLSREIESATEGAYTTRVCIKKKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCV7</accession>
    <name>A0AAV4UCV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="8">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RDR1</name>
        <name evidence="11" type="ORF">CEXT_16001</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01012651">
        <property type="protein sequence ID" value="GIY55552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058752">
        <property type="entry name" value="RDRP_C_head"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26253">
        <property type="entry name" value="RdRP_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 8 11" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="RDRP C-terminal head" evidence="10">
        <location>
            <begin position="157"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY55552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="554" mass="64751" checksum="D66B67A90A78126B" modified="2024-11-27" version="1">MGGSDLDGDEYSVLWDDDLIFHRNNERPAHFPSPAQETSLYIRDADMINFLVQYIKNDQVGAIANAHLAHADRQDIFSNICIKIANKFSFAVDYAKTGVSRHLEPNERPTCFPDFMERNYKETYNSKKALGKMFRVAHDYESENKEASITYQDIQMDPDLKFDGWELYKENALKSRNKYNALLKTLLRNYGIQHEAEVFSGAFTNLHCRFQERKDKDEIEKVVVRCMKRLAKNMYEEFLEEFKNFGNVKEMDVRILQKASAWYVVTYSDNNAKFLSFPWTVSKFLANIKLRKTGNQPVLFSPIVVKMDEQIKMHESNNILPHPIHSSLWQDYNYICDSRTVQLAFRVLLLWARDEELLDIYHGIIMDFNVFLRLFLHVAESANYIVSKMNPVSSNERKFSAASLCLEFFSFCLKLRFYNPKEIKEMISFPVHNYNKLSKRAVVAYHKFALLGKFNNLYADDYEEERGIQMKPIYIESKIFPYVPIYVASLQKAEDALRKHSKAEDVSLREIRQTKKVVVSAVGTEQSLKVLKSFLRKKHVWLKELFTTGNLPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDY3</accession>
    <name>A0AAV4UDY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Palmitoyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Zdhhc11_2</name>
        <name evidence="2" type="ORF">CEXT_554901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012717">
        <property type="protein sequence ID" value="GIY56035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="486" mass="55140" checksum="86FFE7ED2BD8868F" modified="2024-11-27" version="1">MCQNFSTYDYIVHKRDPIASSSKRNEKNKPRPNFDCHLQLLQHLKSKKRNQISPKSQDNSKEDGEEWEMQANVQHNKPFENKKPVMPPVTENKCAATNEEEECPLENYVGNVYIGSPHRRRHYLEPLNVRQKQPGPKNKDTKKEDISSKKENIPKQVNDKDEDNLTDGENQDSSTNSQNQTYSHGLPRRHHRSPSPAPLLSPILESEISSGSAIVSWKHRSVSEQSLHTLDESEEDTAAVPTTCTVQIEPSVSKGLGSREDSGSLSNLFLSKDQLEDLEEDNNNTLIDDDNRVHEVCIIPQNMQESCEGNHNMCNSLEAIKNDKSDPIVNGEVWAYASRNGQIRDGIISFRRSCSMQDNERLKNLSSDQLTRCCSEDELKSAQRLTKLQRRLSEDHDLWMLKGGNNIPQTWKEHSPKAGISATAVFCVDEPEESFRIPGIPFGIKRKYNHFSVPNHIVLPCSNSVHPESRKRTRPVGSKPPKAFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEI1</accession>
    <name>A0AAV4UEI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_537631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012728">
        <property type="protein sequence ID" value="GIY56089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10864" checksum="5F7278427DD52A49" modified="2024-11-27" version="1">MIGPSWYYDWIKIGIMIGPSWYYDWIKVGIMIGPSWYYDWIKDGIKIGLKLLAMEEKYPEPRWTRIFTDGSQIDEIAGRHMSTLSCFPSLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UR30</accession>
    <name>A0AAV4UR30_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Receptor ligand binding region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_220861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013331">
        <property type="protein sequence ID" value="GIY60457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UR30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Receptor ligand binding region" evidence="5">
        <location>
            <begin position="2"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY60457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10052" checksum="9872743D690A79C8" modified="2024-11-27" version="1">MYPTFARTRPPDTQISKSVASLLLSFGWMKVAFFILQHRTGTSRKFQEPSSRRWTGSASKFDTSALGQKLTIMVMAKILLMSWLKTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4US16</accession>
    <name>A0AAV4US16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_771821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013342">
        <property type="protein sequence ID" value="GIY60564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4US16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12266" checksum="27357DD8A1B2749D" modified="2024-11-27" version="1">MPLYNLKVSFRFAFFPPLKEANSVEIGPKLTSWNELTISRKIDCKKCGIVGFKISQTLSPTYKIPHRKILLTRNLPLNDAALFDKSSISPTFFLSRCERLDPKKWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVB3</accession>
    <name>A0AAV4UVB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_82261_1</name>
        <name evidence="1" type="ORF">CEXT_472161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013490">
        <property type="protein sequence ID" value="GIY61593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="280" mass="32919" checksum="2BA5EBA7F44439D0" modified="2024-11-27" version="1">MSLDVKFEVFSCHIFRHFFTAIYPEIALRDVRDLYREERLSESDYEDACSGIYISAVKCLSVLTNYSQTEFINNSREEYSESLSDFYDFIIRACNRQDFFGSLTIFERMLSTVEFVMGLGMCCFVNSIHFNTSPVLYIPLSWAMYFDRHSQEFYEQGGWTKLKEVALLYDYLSNSVHRLFALNYRFKVETTIANRVNECVENVLSFQKTLTPFEYKNLVKSWVKFSIQNRKNSCNRNRENPVNISILGMNLISICDNLLREQKKKSESNLQSTMNQETSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UW60</accession>
    <name>A0AAV4UW60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_433401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013556">
        <property type="protein sequence ID" value="GIY61963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UW60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14375" checksum="76DD139F0E58E289" modified="2024-11-27" version="1">MRGDLFARRNESPTRVSRHLNLTRRWIFKLSLENSKLAMRIYTNFTAYNAISYAYCRTDKNAESLLLGCQQRHSRLHELDNNCIQRPALRRESHLSHQRRLHQVSGTSTQRHRLSSLGPASSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXC1</accession>
    <name>A0AAV4UXC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cathepsin L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_622091</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013633">
        <property type="protein sequence ID" value="GIY62556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000006">
        <property type="entry name" value="Cathepsin S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="8">
        <location>
            <begin position="11"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="7">
        <location>
            <begin position="98"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY62556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="314" mass="35148" checksum="CF5DCCF94FFDE920" modified="2024-11-27" version="1">MLFDPELNEHWENFKKAFGKHYDGKEEVARRLIWEQRVADVVRHNLRYDVGIHSYRKGINEYSDMEHREFVKAFNGYRGHHGVQSNSSSWVPPSNIRIPDKVDWRDQGLVTPVKNQQQCGSCWAFSTTGSLEGQHMKKTGQLVSLSEQNLVDCSGPEGNQGCEGGLMDQAFEYIKKNHGIDTEESYPYTAEDGTCHFKKADVGATVTGYVDIPTGDEDALKKAVATVGPISVAIDASQDSFQTYQDGVYDEPECSPDQLDHGVLIVGYGSEDGSDYWLVKNSWGKTWGIKGYIKMSRNKDNQCGIATQASYPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5F8</accession>
    <name>A0AAV4V5F8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_300331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014001">
        <property type="protein sequence ID" value="GIY65526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5F8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16334" checksum="00AFC95BCA233381" modified="2024-11-27" version="1">MKTNTRVTTQPKLITSPNEESPHISVTQLPKITTIVTATVIFAAVGNDSQSMSRRIRTDSPRGAGDSANQTSPCASGPKQLRFHSAKVEINNVFQKHSSGWEMQNDICIFMADGLPQGSFESSDFCTEVWTVFKFLGEEVIILDGLTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBZ3</accession>
    <name>A0AAV4VBZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_745271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014188">
        <property type="protein sequence ID" value="GIY67020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13136" checksum="5E5EC2BD08BDD0B3" modified="2024-11-27" version="1">MKGKKKKKSTIFKLDLAKKIQTSPNEAIAQPTWQPVRLMWRQLRERLPPKNHHSHTRKGKESGRGRNGRSYCILSWELECWKTKRSLTRPPSTTPRGESKDRPFVSGATPAQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGZ0</accession>
    <name>A0AAV4VGZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_544131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014504">
        <property type="protein sequence ID" value="GIY69215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13417" checksum="DD03BD2CC3D63886" modified="2024-11-27" version="1">MSRSIIDSTIVTPTSSTEKSRTPMLIRQPSIPALLEYRPQPFLRKFIHSNHILKFTNWFPTALKNQTQPLLRRSMYQYRIFDIYNLVPSISRDRMTYLPKSSVHSYHFPIFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKU1</accession>
    <name>A0AAV4VKU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_207161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014640">
        <property type="protein sequence ID" value="GIY70249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10489" checksum="9BF34360D0775802" modified="2024-11-27" version="1">MSLFTLLYAVRVRNVPIPIMSLVDFRSCRAKDDYCTFWADYAQRNVINFAYHFINNAESIPQWKGNTIDSLKIGSIWTAWGVSQFKNLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMM0</accession>
    <name>A0AAV4VMM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">spop_115</name>
        <name evidence="1" type="ORF">CEXT_771591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014842">
        <property type="protein sequence ID" value="GIY71691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="547" mass="63923" checksum="FCB966B64AD82C0B" modified="2024-11-27" version="1">MARVKDFTFEWQIENFSFVSGKLRSAPFIAFSIDKDAKWQLQLSLKLSPALGREICVIGLHRVVNHKGIEIIHLEYRLTVVTLDESFKAKNYMCSFPRDGSRNEENKMALLDVNKYLKMRKASYLPSDTLTVRCWMARNEAIPVKRLPRSDVGPKYCLARTWFKVERAAFSACMDNFSEFSEDEIVEMRIKSASHNYQPLFVELSLSDQGMIMMRLVFERNALGRRYTFRWYLLHVWGMKTLLGCREYSTNLREIKFPINVSKRYILGSRNIFLVNDELSLHCEILMTEPQEFSKLEKMEWNLPPLHKKWPFPSDIRNQLLHALEEEKFTDVEIKRKNMMFADEYTVKAHSVILSRQSPKCGLFLACDSSGEGIPTVVQTTIADISILRWAIYLLYVDGDVDWLSMENTIELLRNHDIVSPLVKAKLKKHFEILLDLNNYCRALRLSFESYAWDLVKIAQEFVLRNEQVVFGTAQWRRFEQQCPQLASDTMAISHLLKPGFFNIALVFDGMQFHRAVCSPEFNPKYSSGIQWETTYDSGEHFHFYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNU1</accession>
    <name>A0AAV4VNU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA 3'-terminal phosphate cyclase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RCL1</name>
        <name evidence="3" type="ORF">CEXT_579701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014752">
        <property type="protein sequence ID" value="GIY71070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF1">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase insert" evidence="2">
        <location>
            <begin position="94"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY71070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="232" mass="25385" checksum="0AE4C46EBB5523B8" modified="2024-11-27" version="1">MNERLHQAQQTKNYEHNFLKLLDNITDGSSIVVNETGTVVKYRPGLLIGGKLQHDCGIERSIGYFLEALICLAPFCKKPLEITLKGVTNDGMDPLKNSGKSPGFGLILMAESTTGVFYSAEAISKPSGSGEDFVVPEDVAKQACYKLFEEINRGGCIESFNQSLACLMMALGPADVSKIKTGPLSPYTHIEDFLQLRMKLETEKDEDLQTGTHKVIMTCVGIGFSNLSRSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUP8</accession>
    <name>A0AAV4VUP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_481481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015028">
        <property type="protein sequence ID" value="GIY73050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10980" checksum="CE8B92FBE3F3B311" modified="2024-11-27" version="1">MDCGSKLYLGERSGDTSMSSSYSRGIFQFTILGGKLVICDLLFGLNSVKSDSSPNLPQPIEYQQILNEFNTCGFSSKHSRGTLQFKFDTLIYGRISGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVN2</accession>
    <name>A0AAV4VVN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_629581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015205">
        <property type="protein sequence ID" value="GIY74337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10238" checksum="EA4ED59D98BE7F0E" modified="2024-11-27" version="1">MEKKWKVAQQLSVDLAATPSEILGFRDPCYLPPVSQSQTLGPSPPPPFHNMRPRSSSQSRQRKSYEDSATPKKRPPPPPPKRSETTQLSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWY7</accession>
    <name>A0AAV4VWY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_591581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015279">
        <property type="protein sequence ID" value="GIY74965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18962" checksum="30DAB4DA3C3452CD" modified="2024-11-27" version="1">MMMARITAVDTATRGTTVVLEGFGGHVVDRFDDVLLQDDLHARNFTKVRRGGTKETCWSYLGTNLLLQKTALFTRWWMATCIQLNTPNQTRRYKFGNSEPSSETIRREADGSFENMFTLIGCFNPPPYEKKGRLLTLEEEEIKNEALEGNEWRTEHEVGEECYAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W1M9</accession>
    <name>A0AAV4W1M9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_509231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015413">
        <property type="protein sequence ID" value="GIY75901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W1M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15803" checksum="1892E07AF2787E24" modified="2024-11-27" version="1">MRNPRLLFPSKSYSKTLLSIEDLRIMAFGSENNGVSPENKSRHSRAKQCSILFVYDILKVFSQQNGQTKSYSKIPFYRSSENNGVWRSADYHRKLTLDIREPNNVLFSSYMTFCERFSPSRMDRRERNGERGCIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W544</accession>
    <name>A0AAV4W544_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LHFPL tetraspan subfamily member 6 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lhfpl6</name>
        <name evidence="1" type="ORF">CEXT_268201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015687">
        <property type="protein sequence ID" value="GIY77832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W544"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7818" checksum="BDA865F80473ACD3" modified="2024-11-27" version="1">MEEIEDMVFVEQLNSFVHQWLELGNIFENIPDIPNLRLVQILPPACIALALTTGIESALSRHYWKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W714</accession>
    <name>A0AAV4W714_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_575281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015734">
        <property type="protein sequence ID" value="GIY78251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W714"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13984" checksum="591C1F06903A7B0E" modified="2024-11-27" version="1">MKFQSNTISQNSMHYYPVIQSHITNFSPIQYPKIPSKTNIPKSSLISQIPGQTNIPKIHSNPIFQNPVQSHIPKIQSNIQIPVQSDIPKFNPIHILIQSMSQIPVQSNIPKSYPIQYLKITSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCN8</accession>
    <name>A0AAV4WCN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TLDc domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_75596_1</name>
        <name evidence="1" type="ORF">CEXT_79241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015909">
        <property type="protein sequence ID" value="GIY79619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7522" checksum="12FCFF37FDD05290" modified="2024-11-27" version="1">MFAIAPHPEYGPIFGAGADLCISHNCNANLESYSNLPHSYDGENASCTLLMGDYNFTVLDYEVFTTLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDK4</accession>
    <name>A0AAV4WDK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CEXT_203081</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ankyrin SOCS box (ASB) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016029">
        <property type="protein sequence ID" value="GIY80606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045732">
        <property type="term" value="P:positive regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051573">
        <property type="entry name" value="Ankyrin-SOCS_box_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136:SF15">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24136">
        <property type="entry name" value="SOWAH (DROSOPHILA) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="10" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="12" id="KW-1053">Target membrane</keyword>
    <keyword evidence="7" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="10"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY80606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11858" checksum="05EB4AF7CB6106F9" modified="2024-11-27" version="1">MNADFHIPQNGSALLHEVYQLDKVKYAELVLKQGANINAFDQRNRTLLHDACHGSSACVELHLKMGADAHIPLSARTLLHGAYLLGEIECAEMLLKYETNINAPSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEY0</accession>
    <name>A0AAV4WEY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_805651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016016">
        <property type="protein sequence ID" value="GIY80536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7783" checksum="254DC25F1292B47F" modified="2024-11-27" version="1">MGEMHYIGTTYGVKRVEKLTNIVPLLFGLNTLGGEPGRESGIQGFHRGKDILHGMLDMTDPSLPLSDNIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WI95</accession>
    <name>A0AAV4WI95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_776731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016143">
        <property type="protein sequence ID" value="GIY81584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WI95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8126" checksum="9214ED7476071711" modified="2024-11-27" version="1">MPVIRQRFSAAEWGVGVTAPRGAGRSLEDPPPKYRFETTNSRPTPVVRALAAAHNSWVVTTCLGDAFLANFSHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJK6</accession>
    <name>A0AAV4WJK6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BPTI/Kunitz inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_237371</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016204">
        <property type="protein sequence ID" value="GIY82049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="74"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="219"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY82049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="33680" checksum="1964B259ABC23D35" modified="2024-11-27" version="1">MSMWYYETLDNTCRNFMYSGCGGNGNRFNSSDECYKVCRTESHQAVPDIDVNEEDIESAVLGNVPPNTFSTKIERSWEDGEKDEYRNNTRKQSETIEIKERENNNEKNNNEKKERERTNRMNNKRNESIEEEDNTTGRIKDNERQRGKNKNDRKNSERGRTTKYERGDRMTKKDERKDSKSDRTKEYEMKHEENDRTKGENERRYVAAEKVMKPIKSGSTKENRRNQNGRMKENARRTEINNNRKEVKESDRNRNRSDWGTHKKKENDEEKKEKCRSKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQ22</accession>
    <name>A0AAV4WQ22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_30791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016412">
        <property type="protein sequence ID" value="GIY83640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQ22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="203" mass="23257" checksum="CA0EDDD13801664A" modified="2024-11-27" version="1">MKVYFPPSLLNISLSKVAVSICYAKDLNYLMAGFQYRHKCDHGETRDLIQSVVEKGNEIIFALQIPKSLKETLTGVFKATVLDINIWFSEHKFFLHIYFDILSSLHWNAEGSINRLKTAQALIQRNEASDILLLTLAATYCLEVDLERLWVNVVISEEISQWLNHISMIWNITGAVTGFKSFTIYLRIVSLELTGLRLRMKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSH8</accession>
    <name>A0AAV4WSH8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_712221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016631">
        <property type="protein sequence ID" value="GIY85238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSH8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13077" checksum="D44EADD8FE2A11D1" modified="2024-11-27" version="1">MPRGLFGIPLTDRPHQPQTHFLSRENEVTPLLTSSCLCLAHLLLKVGWPVDHSLSFLKYYFLSRRNPLEPGKPPFPLRWGVGYFGWNPVGGGPALPSTVPRFGLRPVRMKREESGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WT50</accession>
    <name>A0AAV4WT50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_199001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016659">
        <property type="protein sequence ID" value="GIY85449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WT50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13931" checksum="06D64CABFF1B3258" modified="2024-11-27" version="1">MYLRRVEEVAKQIAVVKRNDSFKGVKKKKKIGHSSGTCECPQKMASSRRMRHPEPSIGPLLKFRPDWFRGDSSGRLRCLTDPGYGKMGVMERERERDFPVRGGIFEFLEAKRGLECSLPSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUF1</accession>
    <name>A0AAV4WUF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_799481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016744">
        <property type="protein sequence ID" value="GIY86132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="11824" checksum="61939E526AEC7F85" modified="2024-11-27" version="1">MRCFFHFRSPVNRARSMDARAMASPRAPALDLQSVRQRGPRLALLPQDPVPGEQVPGPCPEARQPPPQGDQAQVTQPLALPRLLAELPELQGLQGLGLRSQSRIGQSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9L6</accession>
    <name>A0AAV4X9L6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_512061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017408">
        <property type="protein sequence ID" value="GIY91378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9035" checksum="6E20BD0493C9972E" modified="2024-11-27" version="1">MSPLNTIVAARINTRLGRRQSTCCHSSQNSGRAGCNSLPEVNEVYELKKSCFLRFGAIRIDGATVAKRAHTPNFGQEDLRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAH2</accession>
    <name>A0AAV4XAH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_394861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017415">
        <property type="protein sequence ID" value="GIY91448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9923" checksum="31E385BDDF1DC4A3" modified="2024-11-27" version="1">MQTEVILNGQKSISNLVRFMWFEMSPMPIALPCNSLRRGRRDVSGPEWPQLVREKRAICLKHNKEQLIKGQCEAGDNPQVPPTPPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCS4</accession>
    <name>A0AAV4XCS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Facilitated trehalose transporter Tret1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Tret1</name>
        <name evidence="10" type="ORF">CEXT_395351</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017579">
        <property type="protein sequence ID" value="GIY92711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000055">
        <property type="entry name" value="Facilitated trehalose transporter Tret1-2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="13"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY92711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="461" mass="50559" checksum="48A6F286A676102D" modified="2024-11-27" version="1">MKFLFLPIVNLKNTHFATGSALLYIIVLGMVNSYSAPATVDMQLPGSRFRDITPDEITWIASLPPSFWCRWELLSGYVTHKLGRKATLMFISTSYTTGWLAIAYATSVPIIYLGRLISGFSAGICAVAVPTYIVEIAPTEIRGFLTSGFQVAFSVGVFLVIGLGAVLRWSWLAISGAVLTTSAVCLMVIMPESPAWLVQESRIGEAMKGIKFLKGKNSDLKKELQDISENQILSESNKFSFREFLNPTFYKPLGFAVLLMVFQQVSGVNIVLSYTVEVFGSIGSSVDPNIASAVVAAVQVGGTILSSFLMDKSGRKRLYITSATCMSVSYFALGVYSYIVKKSEHPVNLHYYGWIPLVSLIVYTFAFSLGLGPIPFVMAPEMAPIRFRSMIVAIGSLMCSLSGFIVTKTFEDGRALLGIYGLLWLYSGLCLLSALFGWFILPETKGLSFREIHRSFSVPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD36</accession>
    <name>A0AAV4XD36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_359511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000232">
        <property type="protein sequence ID" value="GIY93097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7505" checksum="AF415A07F91EE34A" modified="2024-11-27" version="1">MIFGGSTRAIPGHQFSTPFSCSWCPKRENAISSPLILSVTSDGVMGRRENMCRSFQLQELDILVDGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD93</accession>
    <name>A0AAV4XD93_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase aspartic putative domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_767311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000076">
        <property type="protein sequence ID" value="GIY91965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="19156" checksum="0DEAB97B8FC82594" modified="2024-11-27" version="1">MCPELKQVVSTGSDKLVAKAVENSNEKFHTLANPTCSADVLLQTLVVYLYGNDGNFPVRALIDTGSQKSYITKEAVSKMSYEPIRAEDMIHNLFGGVESKQKHHLYKVYASSFQKDYHCSFEAYDQETICIDIPTSICGPWTKEIEKKREYFLATKKPVSMIQRLQCIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHH3</accession>
    <name>A0AAV4XHH3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000261">
        <property type="protein sequence ID" value="GIY93391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9543" checksum="92138B3020566125" modified="2024-11-27" version="1">MFGTPFARSRNFCPRACAITQLMFYLQSAVPPTSGCSCCIDRTAYVVKIDFGVEFSRTLCRAPFLRKEYGRGKHSNELLIIASPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMH4</accession>
    <name>A0AAV4XMH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CUB and sushi domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Csmd1_1</name>
        <name evidence="6" type="ORF">CEXT_449171</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017888">
        <property type="protein sequence ID" value="GIY95264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051277">
        <property type="entry name" value="SEZ6_CSMD_C4BPB_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45656">
        <property type="entry name" value="PROTEIN CBR-CLEC-78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45656:SF15">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="Sushi" evidence="5">
        <location>
            <begin position="47"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="232"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY95264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="309" mass="34173" checksum="8BD7B6FCB548053D" modified="2024-11-27" version="1">MVAGKVLNVMFTSYVSPSSEPHLKDKNETGADGIGSFQIRYKAFDPHRCGRPEQIENGYTVNKGRKVGQTVFYHCHPPYDLIGDSELHCIITDETPVPKWSNKTPKCVIQDCTEGPTVKQGSHGAIASQDILLTFISFQSPAFGEIVTQPNHQIKAKEETGFYLEYSIVSSSCPKPKAPENGEVIGYSTDLGSSVAYRCNPGFVLKRQNNLKMEKKKAKESLSVKDGFNVTETKEKSSVPKHQLIEPVPSSSESAEPNENNPVKKSEKEPGSGPKSEPHLLQVIPPKMAKRSHLQKKVAYQSKDKDPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU58</accession>
    <name>A0AAV4XU58_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_625111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000776">
        <property type="protein sequence ID" value="GIY97399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12618" checksum="1DDB5071A415274E" modified="2024-11-27" version="1">MLVELLPDGKGRVALGVAFAVVPLTTCLGVSLKPSASSGLFQYPGGVEQRSALVFDCCEQEWWLLVLLCRGIPPGLSVHLWSPVRRFERYGGWHSVLHLLEVSFMYEVVLFGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVN7</accession>
    <name>A0AAV4XVN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_679561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001003">
        <property type="protein sequence ID" value="GIY99101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8983" checksum="954062F2384FD8CA" modified="2024-11-27" version="1">MLRGIRTRITFPAKSSIFRCLAHWSSHGWLESNSCDHLSKSDGKSLQGVFAGSFRSLPNILLICISDVSGYTSNVWILIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY56</accession>
    <name>A0AAV4XY56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">G patch domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPATCH3</name>
        <name evidence="3" type="ORF">CEXT_29401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018387">
        <property type="protein sequence ID" value="GIY99125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039536">
        <property type="term" value="P:negative regulation of RIG-I signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032480">
        <property type="term" value="P:negative regulation of type I interferon production"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040341">
        <property type="entry name" value="GPATCH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14390">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14390:SF2">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="375"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY99125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="486" mass="56792" checksum="3F517B5BF0B44116" modified="2024-11-27" version="1">MQHSVQQRNGVYVIVNNIPKEFHSSHLRNFFSSFIETGGFVCFHFRHRPEIQKPSHLIDKSDSEKSRQVSNCCVIKVVPDRVDEFIKTYNGEHWLDNKGETLSTCCFLKRINLSKEDDSYHSGSTSFKKGTISTNLPLDREEFSNQDVESLIEMHPPSFMPNGNIGTKTNHFLNEIRACRLPPSLISKLGLQFPRNRSRRIYGSVGFDYRPKREQLRSKNKIFAIPDFEPTFHKKPWCSRLPVEDLEQDNKEDKEESESEEEEWDRHESLHDDVTGQERNKERLFEEKIELKWEKGGSGLVFYTDAQYWDAKEGDFDAKTSDDWDIDTRIYEQPGVDNDKDMKDLIRMKLEEKNRTGTETERDRLYDFAAFEKYSKGIGRKLLEAHGWKQGQGVGRNAAGIAEPLPNEGQRPFDKKGFGYRGEKLNRRPAREKRKRKYRDSETLEDDFFISTIYDDPKVSDPPESVFASSSFARLKYRQEFLKECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZX3</accession>
    <name>A0AAV4XZX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001048">
        <property type="protein sequence ID" value="GIY99454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12128" checksum="61DA2D0D31E39D4B" modified="2024-11-27" version="1">MARLLSARNELAIPICLSCHISPTFGFSSQTLFIAIFLITRHHISLDKRLFGWAKRRKASLSTPRVSIDGGPAHCGVSFLDWRFRFLILLHHFHALPFRCRSAQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M2X6</accession>
    <name>A0AAV4M2X6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_501011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001822">
        <property type="protein sequence ID" value="GIX66802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M2X6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9889" checksum="B9F6079AE6DA5CB7" modified="2024-11-27" version="1">MQTYLLRKFKEPPIEVAWKTAIRSPDHEDPQCNSIDFCESENSKSLHPRRKEGEKWMEAEIYLQWFHKGKSTPYAFFFPFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9K5</accession>
    <name>A0AAV4M9K5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_810881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019543">
        <property type="protein sequence ID" value="GIX69061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10692" checksum="B47BBD651BE0AA7D" modified="2024-11-27" version="1">MLEVENNVVGFIVNNSMVCFGKTASHKHAVFNAMVENSIAGFVVENNIAYLVVKNNVVGLAVENNVVGLVVEKKKKYYMLLGKQHCMLCSGKHYGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGN6</accession>
    <name>A0AAV4MGN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_736481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002225">
        <property type="protein sequence ID" value="GIX71498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13534" checksum="F30CD5E78FF0A3F0" modified="2024-11-27" version="1">MSQKGGPEYFLKKSSAHRKTVERYDASADRTGTASSSTTPSSSTTASSSTVDYLVICQININYLKIIIIMASNDGEDADCSSSLSSEEALSENEIEMEQYGCEICKMPVRKKLNFPDRRFGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHK4</accession>
    <name>A0AAV4MHK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_650621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019812">
        <property type="protein sequence ID" value="GIX71994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7034" checksum="9BE0749243D5D2AF" modified="2024-11-27" version="1">MVGNGGAKEIKPIATTFVTSPTPPWLLCCGAKGENNPISGERLALVRGVSGVGTGCLNEATNVYLWIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMC5</accession>
    <name>A0AAV4MMC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine-enriched protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gprs</name>
        <name evidence="3" type="ORF">CEXT_556441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019967">
        <property type="protein sequence ID" value="GIX73569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051481">
        <property type="entry name" value="BTB-POZ/Galectin-3-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410">
        <property type="entry name" value="HL07962P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410:SF46">
        <property type="entry name" value="SERINE-ENRICHED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="118"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX73569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="20090" checksum="04B2130CD612DF4D" modified="2024-11-27" version="1">MFLHHHFVVRFSAADMSDEEEEDDYSVFENKMGLAEDMKFLASMPELCATSPSSSGNQGNRSSTRFCMDNSSSSSKHPQGSPREEARIHQRYEAENVPQNSEPLLNIQAPQMPTGGHQTLIVEEFEPDVFRQLIEYIHTGCVTLQARTLLGLMNAADYYGLDELRKACMGFDASLYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNX3</accession>
    <name>A0AAV4MNX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_454321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002422">
        <property type="protein sequence ID" value="GIX73535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10351" checksum="1EA4D8FBAD64199E" modified="2024-11-27" version="1">MYTFSKGEAEVKRDRNKTEDTRDPYLSCQSFYFSVSSRRFTFCRGKFPTDKSTQPEKVRRFEKGPSSSHFRKGSPRKPLDVLCLCLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR21</accession>
    <name>A0AAV4MR21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_150691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020048">
        <property type="protein sequence ID" value="GIX74268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15337" checksum="560CBDF8FF38BE87" modified="2024-11-27" version="1">MDAFWIPLEKLPEFLEHKEGVSSAAKTDVELGRALVTNMVTILLHPSNCTVLQELYNSHRSSTETHESPATFFPPENTMALAARKLDVRQQIDLITSQDGIKWTLHFDGLKKRRLLWDDVFIASYINRSDGPISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRQ7</accession>
    <name>A0AAV4MRQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Pde8b</name>
        <name evidence="6" type="ORF">CEXT_754741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002561">
        <property type="protein sequence ID" value="GIX75121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="157"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="5">
        <location>
            <begin position="427"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX75121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="560" mass="62075" checksum="B00AA6D8000218B3" modified="2024-11-27" version="1">MDPSFLTHSSSFIRFFLNPSSVGTEVGAPAGPEFENYNRLYLPKELVPDHMKGDAEQAYHASTSDGLTHHTSANCCCLGCIIFSVVGAACALAPDILIAEFYAVTHELVPITTNPDIIIPYYRVLIWFVESHNLGVCLNELIQIHHTDISYLLKLRAAQALFSALDSCREGIIVTNLDHNIQYANKASEKLLGYTVEDLCGKNAQTLCRAESVKADIAESINMQVKKGKDWEGTLFHKRKSGENLPLWSRIQSVEIYSGHAELLIHVNECPFNEKSFATEPADLLPFVKAPRKGSCDVRTLSGESGLNRRQSFAKFHPMTLEPPITKVINMILATQEHSPLFVVQALDRVLDILRSTDIYSPQFTGIRQNHADDSVASDLFSGLISNSKQVIRRFSHEAFKASKSVLGVPSSGAVAQLPLTPSAVPTLANAPEKVKELLEDVKEWHCDIIQLEKISEKRPLIWVGMAIFASFNACNLLNCDESVLRNWLSMIESNYHSNTYHNSTHAADVLQATAYFLQKPRLKAIFDPIDEIVSLVAAAIHDVDHPGKTVHFCAIQEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MT54</accession>
    <name>A0AAV4MT54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium-dependent multivitamin transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CG32669</name>
        <name evidence="13" type="ORF">CEXT_301091</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002517">
        <property type="protein sequence ID" value="GIX74622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MT54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051163">
        <property type="entry name" value="Sodium:Solute_Symporter_SSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985:SF40">
        <property type="entry name" value="LD47995P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985">
        <property type="entry name" value="SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX74622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="327" mass="36014" checksum="AC8BBBFD84895AC2" modified="2024-11-27" version="1">MLSVGDLRRAQHALLLSLPLILIFNLFTFWDGIVIYALFHDCDPMKDENVNLNSPDQLMPLTILKLFRHIPGLTGLCISGVFSASLSTVSSAVNSLTAVTMEDFIRPYCFCQRLSESWMAFIAKILAVGYGVLTLLLTFIVANFRGVIEASNVVFGMVGGPILGIYSLGMFTKTANEPGTMIGLMVGFVVNAWMGFGSYLTKHHVPALPQSTAGCPVNSTFSPIEFVNTTEEVFLEGGIEALGLAQEEEKYIFPVYKMSFMWFPFIGSCVVFLVGYAASFLLSYWIHIPDVRPENMSPFVELSEKKDSENDLSHVSNGHTNIAMVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTM9</accession>
    <name>A0AAV4MTM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002570">
        <property type="protein sequence ID" value="GIX75229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10912" checksum="ED80D33EFDDB4869" modified="2024-11-27" version="1">MLVVSTYTCDQCGAETFKTVNSLLFMSLINCESGSNVDDRNLEEDCICRLSDQVPEDDALEDHELTQAKAEEILNIYNYDMMASSISPEIFCIHHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MW98</accession>
    <name>A0AAV4MW98_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_407741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002569">
        <property type="protein sequence ID" value="GIX75209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MW98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="16219" checksum="0DDBE680B45C162B" modified="2024-11-27" version="1">MFIPEYIPLSLSSGVDTEMTLIRKKDFRRVLQSLCHQSKRYNTKRPFLQSLQLTSQAFYPSQAQDTLEERTPICHLHFRRIPFSLSSLVFLNKGKRRNCEELFAVTTILLEKERAGLLLVIRFRKDPPPQLPFRIIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXL2</accession>
    <name>A0AAV4MXL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002733">
        <property type="protein sequence ID" value="GIX77236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="14279" checksum="28490670BD5EEBF2" modified="2024-11-27" version="1">MTQSNKKVFQQYMSLDSFGTGWNGFIELQKRSMSGQGAREIFHCCIEMFPWEFELFSELDLEERQKFLMYFVSNRTLPLDDFRFFISTMEGKHLESYFGCILTKSFNTSFSGRYINIFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N191</accession>
    <name>A0AAV4N191_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_167851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002756">
        <property type="protein sequence ID" value="GIX77441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N191"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9506" checksum="C54ECE8620C21C70" modified="2024-11-27" version="1">MFKHQFFKTEEYPQTSDLREFIDICEEICLSNSYEEAPAVFDVPSYACAVAASVTCLIQTSARPLPSILHHTPEAMKPECVFMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N755</accession>
    <name>A0AAV4N755_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_118283_1</name>
        <name evidence="1" type="ORF">CEXT_794791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020600">
        <property type="protein sequence ID" value="GIX80522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N755"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="723" mass="80200" checksum="2205442E604ACC60" modified="2024-11-27" version="1">MAKAGVDFRRIESSKCAISTPKTVNLEIVGESPESPSELDFSNFFLKQHIAQNGEINSNYASGRNNATDKDLQLSFILHDNQQASQIKRANDTEIDVGLLELLNSTKLTTTSEPCGGKFKSKQDSSSCVGQKMKFKSNFQVSDDLLSSFAIPDNTVVKNNSTKFSLFDCNEDDIVSNSSSNNDKFLPENSVVNSSFKVENGLSDLLSSINIENSKASSFHSFDNKGDCQKISNNSKSDVEFSLSDMLSTAELNDCKLSSWNSNKMTASNDFQDSDSPSLSELLSSLHHSKISENTKDEKTLKENTDTSLLDLISSVQVPDSKVSIDTKHANVINEKEETSLSDFLSSINIDESNTSRFDGSTSSTKCDVKSSSNLINYIESNLSDVLDFDFDQVSDFRKDSSSESSFNLGKEKNNCKNLKLESKLKVEGDDDQTSISELINSFNPQCTNPIPINKSRDTKLENDKDILRDENDECLTMFDLMKTISPEFKNIDSANINVKPTKNSDKLATENSNCTSRTNIIKSINFNLKEYSPQNLKCDVANYNGVIGNDNVDMNILKVEDSAVENMNDFFNDDEQITCVDLRACIKTEKSSSSPNELKEPQNQVSGKLSPIKFPIYDELCISPAMIHPKSPPLWTNTVQSMSQRIKPTLFSKALAAKPKKDSSLLQKVSSIKSKLLKSIYYPTLLNCDTPQPVNEPVIYKNSCILHFAGRRTFGLDASFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDI4</accession>
    <name>A0AAV4NDI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_370381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003270">
        <property type="protein sequence ID" value="GIX82882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="22774" checksum="39AE1DF86F89923A" modified="2024-11-27" version="1">MLFPSRSSEQEWRRRQKKCSSYQFDVTIRKSRAKMSFVGRCYSLEEAAIRNGDDDRRNVHHISLRLQSGRSGRRCHLLGDVILLKKQRTGMETTTEEKCSSRRRFGVTIKKSRAKMSFDGRCYSLEEAAFVGSKKQETTDEKKCSSYHFDGTIRKSRAKMSFVAICYSVEEAAGSRNEADDRRNVHHISLMLQSGRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ85</accession>
    <name>A0AAV4NQ85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_97381_1</name>
        <name evidence="2" type="ORF">CEXT_54071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003646">
        <property type="protein sequence ID" value="GIX87070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="324" mass="36737" checksum="FBDF798AC44F381D" modified="2024-11-27" version="1">MALHETYSVRLNPFSGFSDTNFDQLTDFSINQGAYIPNMPLMSMYSKLNDDNLNAMIGLPSLNSQILPFSNPLLSGMSQTPLSRVPHNRNKAKNIRNNNQRPPNGNQQQKPRTAPQKNRGVTLDIRGGGYKVEPKQNIRPYKAPIPESSVRNTQRVNSNNNNNNNNNNNNNRNMRGNPGRPNSNPPRNRNPNQRPRSPSIKNPYYNMKFETSLPSIPPNVEFVNPENVLPFHPRIYKSFLQQNKQFAPYLQNLNKMNPPKTKPQNNRNFGPPYQGNGRNPPGKPQGPKLTRNRGNPASSSFSNPAQFQALIQTFKHQVSYQVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZW6</accession>
    <name>A0AAV4NZW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exportin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">XPO1</name>
        <name evidence="3" type="ORF">CEXT_630011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003869">
        <property type="protein sequence ID" value="GIX89496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="2">
        <location>
            <begin position="62"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX89496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="21654" checksum="A2F3C3CCDE6CBFB7" modified="2024-11-27" version="1">MTSVQVDGMKEHAGFGGPVNGNMMGVPEAARLLDFSQKLDITLLDSVVNCMYVGVGPEQKLAQEILTALKEHPDAWTRVDTILEFSENQQTKYYGLQILENVIKTRWKVLPREQCDGIKKYIVGLIIKTSSDPKTLDEEKVYLNKLNMILVQILKREWPKNWPSFITDIVGASKSNESLCQNNMTILKLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0F7</accession>
    <name>A0AAV4P0F7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_222481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003907">
        <property type="protein sequence ID" value="GIX90030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0F7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9388" checksum="F238553CA788B3CF" modified="2024-11-27" version="1">MNMLNNSENKQSSIFVVVLPPIQKASLAEVETIKRSDEVGSIQTQPYQVHISHTVGPSQASDRRAFSSSESCCLGKREAKAVGRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2S9</accession>
    <name>A0AAV4P2S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bestrophin homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BEST3_1</name>
        <name evidence="2" type="ORF">CEXT_276311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004032">
        <property type="protein sequence ID" value="GIX91517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="276" mass="30363" checksum="9FAB050EAF95DB7B" modified="2024-11-27" version="1">MQIPQEKQNLLVPEFDEEDDEDKIAATYGMGNRGASLWTLVGGKLNTRFSVSNQNLDTVTLESGSNNWKVSNPSLFIPDADLMSDNKPTTGSVYGIHVPDESSEVGSPQPAAQPQKPQHRKSSDHTTGALKKAVKDSHKETSSATEKPAETHLQTTLTNRRQSFDERSLAALQAKSSSRFQSLPDVKKLASDEWEDMAVEDQDNISTANLLVVHEDQDEDGIVMDRPPMLTFTRASLSPCPSSGDSEDYFGHLGLQSATSLTSMNEFHDEEPENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5R1</accession>
    <name>A0AAV4P5R1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_224261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004147">
        <property type="protein sequence ID" value="GIX92687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5R1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13237" checksum="EFC462FE8DE8E3D0" modified="2024-11-27" version="1">MIHRNLTQLTANNSHENSANLIVYLFNFLANTLHSANFKSTGITIMQKQHCYCAGPSLQDVLNRRLPFKNKTGSKNSTKETITIIFSLNYRRCSHKTLVWQKMLKQKKKQKPANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P758</accession>
    <name>A0AAV4P758_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G_PROTEIN_RECEP_F1_2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_150081_1</name>
        <name evidence="2" type="ORF">CEXT_610481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021720">
        <property type="protein sequence ID" value="GIX92874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P758"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="11658" checksum="B4E980ADF3ACD7ED" modified="2024-11-27" version="1">MDKEVAQIPNEANEVKVTVTLVLNASFSWLERPTKNVLTYHLVACIILSSLAITAVAANVCLLVPIFCSSSLKKVVLNQLISVVSVACVLDCSVNVPFSLYCIKTASGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAR4</accession>
    <name>A0AAV4PAR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_574231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004266">
        <property type="protein sequence ID" value="GIX93563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11258" checksum="3A6CDEB2AB8F5940" modified="2024-11-27" version="1">MSFLRVDNVYIIAQTRSKYFIVYNFLVHSSAYQAQYNFYSTGLRSKTACLRQLQRSHTKRIFRNTFVCIDGSCKSHFGSYQGSPWSEVVRYFSLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBZ2</accession>
    <name>A0AAV4PBZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_95111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004395">
        <property type="protein sequence ID" value="GIX94591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="256" mass="29064" checksum="1AE48F39FC12F425" modified="2024-11-27" version="1">MKPGQPQKVFTMQIGGGFSPPIHQESRAKFPLSPCLRREGGFSKETVTSGCQGSFYEENARVNRWVKSEWLGFSLKEGREKKKKIANRPSRYVKLAFSIHSCIGYSECVVGGGEAHKTGNRETDLRNRCVADPLMRKRSLIHPHRALALLWVSSWQHNVIATACPPLPSNCCRLLVQVYNVGATKLIRISDSSRRKSSRFAGMLQAMIIKSPLVIRMLLQTVMFIDVVEYRVENKLFADSMSPNRMNCQYLYAYFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PD91</accession>
    <name>A0AAV4PD91_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 299</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cfap299</name>
        <name evidence="7" type="ORF">CEXT_442671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in spermatogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004463">
        <property type="protein sequence ID" value="GIX95008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PD91"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027887">
        <property type="entry name" value="DUF4464"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33588">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33588:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14713">
        <property type="entry name" value="DUF4464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX95008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="232" mass="26769" checksum="7AD0B738E16B0F16" modified="2024-11-27" version="1">MDSKSELDKAVNVHDVRRLLRLVAHQKMTSCTSSQWSVWGRVPGLFTGLGSSLRFLFTGLGSSLRFVHRFGVESQVFHRFGIESQVCLQVWGRVPGFIHRFGVESQDKDMCRELLVLGYHSEQENYFRDIFDEKKAQRAAETEYQRSIEMRKCAQELSTSCQLMQALASREEDNLSGCLSTIIFVRDVNEKGEEVSAYMDYAHRLKIENWTAYFKGEKKVVPLESDLRQVHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHE4</accession>
    <name>A0AAV4PHE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004695">
        <property type="protein sequence ID" value="GIX96787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12498" checksum="27BD3E81E8A98001" modified="2024-11-27" version="1">MVLVWVKMIGIIGKYIDGNNIDEYVDGYNSDEYSDGDNIGECSNGDNRGEYSDGYNSGEYFDGVDVGEYIDGYNSGVKHIDGDNVGEYSDGDNACEYIDEYNAGEYSEGDNVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJ67</accession>
    <name>A0AAV4PJ67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004738">
        <property type="protein sequence ID" value="GIX97111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJ67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8744" checksum="3089280206A7C29F" modified="2024-11-27" version="1">MFGPPLRKILGARSHERHLPGQVTMWSNNLLAVTKTTTFHTSISYGQVPFLFDWLARILKTLHGFDEKAVNWTLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PM95</accession>
    <name>A0AAV4PM95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_130574_1</name>
        <name evidence="2" type="ORF">CEXT_457051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004630">
        <property type="protein sequence ID" value="GIX96312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PM95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="21523" checksum="E677892C5B42D32B" modified="2024-11-27" version="1">MPNYLAKSPVPLSIEADQGMEDPQANIAVPMNVECQILEKPKLYKARPPAAKARCLPPTNSFGIHKNELNDSNCDINGESAYELDEADEKMLPNAPSLNVASVPSVPMQTPEVLVEEDLAVSLHDLDNIFDTSSSEGEDNMDVPATPSKLVPYDEFSGKIELSRMYPTPPSLEQHAVPSPFGPLIGNDIATSETDAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNN6</accession>
    <name>A0AAV4PNN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_265547_1</name>
        <name evidence="2" type="ORF">CEXT_215171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004703">
        <property type="protein sequence ID" value="GIX96837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15132" checksum="741D5B1765A50CFE" modified="2024-11-27" version="1" fragment="single">YLANLDCWKKLENDTAYCNENFRGISEEDRRTNLTGRLKIFHSCCAFEWHKNCKANAAENKCNAEAKEYLEYVSDMLGGQILFRMCSTTFGHCYRQLYGVEVERPADNFSNTLYSSILVTLVFLVMTMFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNS3</accession>
    <name>A0AAV4PNS3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_167701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004843">
        <property type="protein sequence ID" value="GIX97973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043999905" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13493" checksum="DD9C77988B46DE0F" modified="2024-11-27" version="1">MGVTIPHIIFFCVIICIQCQHYIITLASNSTCSPVKLAKCRCRKHTVLVLWGMSGQNPFHMLSTIGTHTTHSSYSCDISLDLFGSLVNVRSTPFRGLPPGDVDIYRQRKYRQRENVSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQ62</accession>
    <name>A0AAV4PQ62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_211218_1</name>
        <name evidence="2" type="ORF">CEXT_168981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004887">
        <property type="protein sequence ID" value="GIX98301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQ62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="203" mass="22442" checksum="0947F585FD28CEBA" modified="2024-11-27" version="1">MVISTLQRFGTLCMFVGSIFYNIFMLHPSHALEIGFFQLVASMSIIVIGSILSCGLKAMDDRFLKTLGINLYIIGFGYIFHSLFVAVTTMSTYSHAVIGGILLIVAVIFIYLGKGKPTTTSTRFPLLLVIFCSVLITIMHGINIPAAILIVHDKAVVALIISTMFVLNWILLYYISTIKTQNIPAEPDVIFIGRDNIFDILIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUJ7</accession>
    <name>A0AAV4PUJ7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein hook</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HOOK3</name>
        <name evidence="14" type="ORF">CEXT_662801</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="4">Homodimer. Interacts with microtubules via its N-terminus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the hook family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005071">
        <property type="protein sequence ID" value="GIX99605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030705">
        <property type="term" value="P:cytoskeleton-dependent intracellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22222">
        <property type="entry name" value="HkD_Hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000024">
        <property type="entry name" value="Hook homolog 3 (Drosophila)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043936">
        <property type="entry name" value="HOOK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947">
        <property type="entry name" value="HOOK PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947:SF39">
        <property type="entry name" value="PROTEIN HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19047">
        <property type="entry name" value="HOOK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116907">
        <property type="entry name" value="Hook domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="13">
        <location>
            <begin position="59"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX99605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="28424" checksum="373E4FC2CC34AC59" modified="2024-11-27" version="1" fragment="single">MKFDLSTHTDTYTVMSSGRSTLSTEEIYRRNDYPDSKKACCGIARSCHECPNELQISMEGLSGSLIHWLKTFNIEGVNGPVESFFDGVVISKVLNNIDSEFFDEAWLSKIKTDAGANWRLKVSNLKKILKGILDYYNEQITGFRMPDVAALGEKSDIEELGRLLQLVLGCAVNCTQKHEYIEALMGLEENIQHDVMNAIQELMTTELPAPTYQSETYVDLNNQLKGLTQDLHSTKESKEQITQRCHELDMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QLK9</accession>
    <name>A0AAV4QLK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_810621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006420">
        <property type="protein sequence ID" value="GIY09719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QLK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15232" checksum="64F9222510FDB395" modified="2024-11-27" version="1">MTELMLQRNYFLSALEFQNPLPLSHPLRAGFRYIHSEIRLSHLGPRVHINRDETAEVLGPKISPQHCSTMQIKLRKATNASLNRVYFFFCHHVTSTLMICIESSFQTSVLLSRTTMPLQRQKQRFQKLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSD9</accession>
    <name>A0AAV4QSD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hemocyanin A chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HCA</name>
        <name evidence="11" type="ORF">CEXT_17521</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tarantula hemocyanin is a 24-chain polymer with seven different chains identified.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006749">
        <property type="protein sequence ID" value="GIY12160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1280.10:FF:000004">
        <property type="entry name" value="Hemocyanin subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1370.10:FF:000002">
        <property type="entry name" value="Hemocyanin subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.10">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005204">
        <property type="entry name" value="Hemocyanin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF4">
        <property type="entry name" value="PHENOLOXIDASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03722">
        <property type="entry name" value="Hemocyanin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00187">
        <property type="entry name" value="HAEMOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00209">
        <property type="entry name" value="HEMOCYANIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00210">
        <property type="entry name" value="HEMOCYANIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="10">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY12160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="387" mass="44808" checksum="185852C8C5F1BD80" modified="2024-11-27" version="1">MSLLREKQVRVLKLFERLSVAASGEHIPTDQIDPRLSTVGTLPNSAFFSCFLPEHLEEARRLIEIFYSANDFDDFVYLAEQARTFVNSTLFAFAAEVAILHRADSRGIIVPPIQEIFADRFVPADTLIRAFSIATTKPVGDESDVIVDVHETGNILDPEYKLAYYREDIGVNAHHWHWHVVYPSVYDVTFFGKKKDRRGELFYYMHQQMCARYDCERLSNGLNRMVPFHNFEEPLEGYAAHLTHIATGRHYAPRPNGLALHDLRQVDVQDMQRWTERILEAIHLGKVIDSEGHNVSLDEEHGADILGSLIESNYESKNRQFYGNLHNWGHVMMAYIHDPDGRFRETPGVMTDTATSLRDPIFYRFHRFIDNVFQEYKKLSPFTLRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8U5</accession>
    <name>A0AAV4R8U5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_238951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007508">
        <property type="protein sequence ID" value="GIY17401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12794" checksum="BD6CF0AF59C23B50" modified="2024-11-27" version="1">MHFLQRATKVIRLICESGSCVQTQTHEGCNNSVGANLLSYIVSKVKNIKFRHSFIMFCGWMYDVGMKLRLFVYVRRGTKRLHPLPVHPGRKREESRVRTSCLFRARPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBJ2</accession>
    <name>A0AAV4RBJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_7101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007615">
        <property type="protein sequence ID" value="GIY18361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9590" checksum="0CC3F991EBE9C2A3" modified="2024-11-27" version="1">MEGPIEGRKDGRKEERMDGRTKGTMDGRMDGRKELRMDGWMDGWMDGRMDGRKDGWKEGRKDGRKEGRKEGWVEGRKKGRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RC17</accession>
    <name>A0AAV4RC17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_191661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007529">
        <property type="protein sequence ID" value="GIY17652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RC17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10835" checksum="85469EA39B439968" modified="2024-11-27" version="1">MKLDSSPIFPLNFSNSEHPSEGLLSHEPSFVESSLPALIFCRDLLYCAALSAFEVRYSLPRSKSSPSEHPLHPRGTSSKPISRCSQIRGHLFPLSPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXY5</accession>
    <name>A0AAV4RXY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_419071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008607">
        <property type="protein sequence ID" value="GIY25964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7813" checksum="539C65F4BD2EDCA5" modified="2024-11-27" version="1">MKQRETRRICNGDLQNKFQGSRDLHKFAHFEFETLFPFHEVVHSTEFFNQSGKQEGIVLCVEKAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S358</accession>
    <name>A0AAV4S358_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_724781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008896">
        <property type="protein sequence ID" value="GIY28027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S358"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="760" mass="86139" checksum="B3F0DF74B028BA99" modified="2024-11-27" version="1">MNDYDYSLGNQGFSNSNPFQNSQQQQFPAAQPQNNYWGSSQMQSNPDMVQQQIPQPMNDNDYSQGLSDYPSLSNNGDASGQDYPNTPQDAANSNSDGNPVPFSDQAVPRRPGGLRRRRRKFPFRLRNSNRRTGGSSGLQDQPFQDNDNTDYGNNDSVDQPSDSADSGAMAVNGDSSATSETMTEDESQQFPGDVSNDDSFTTFPPDFWKDLFSGLEGGSTEPPVPATTMEDQINSDNMDEETSVTDDPQVPPNVPDDYPGTTYPPGFFKDMLSDLDTAPSDENSQISKDAENDSDLDSTPQQDETQQSEDQPTSDTVEEPDDPKGPRRRKFHRRRKFPFGRFNDPEMTNRRPSRKWNGEDGNSNDNQDGNNVDYSNDESTDSNDQSETSTAENEEDSQTDVPEDNSATDDPQFPSNMPDIFPGEKFPTGFVQDMISGLDKVTSDDGSVISGTRAPRRHPNGPRRRRFRRRRKFKNGENPANNSNKTDSNAFAQSGDVAASNNNFEPSETTYDENSSQDEMNHKPRRRFRFRRRNLRRNPFTWTQEPQESDASNTKTNTNPEEDSGIEPTSDESGFNNFNKPRRHFRFPYRNFNKNPQQSQESDLSNPEADTNSEKKKTIFSQNPLETNSFDTSDDYNGYSLPFDDWGKQSEQTTLDFTNLEQEYPESTTMYTDTTTEDDNVSYQDSNQPENSSQNNKLRVPTQNWWDAIKHKFNNPFERQQPNSSDDITPQDVSTPETKQRHPFDLSNWLKNLKTFISSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGD6</accession>
    <name>A0AAV4SGD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_234563_1</name>
        <name evidence="3" type="ORF">CEXT_91151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009428">
        <property type="protein sequence ID" value="GIY31856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57277">
        <property type="entry name" value="Granulin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043697081" evidence="2">
        <location>
            <begin position="21"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY31856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="233" mass="25260" checksum="C45FA5D5EF8EB524" modified="2024-11-27" version="1">MNSFGLTLAVALLVLGVTSALPRHARSNAAREHDDGPEPQRDGRRDLSGQTAPVSGNRRLLPEGRRKVGLLSKDTANAPNKIFLGAGSAATNWVFIWHCCTPLAPKCKWWGCWFKLTLAVALLVLGVTSALPNQFMSALKDMPDLTQPENTMMGQSLKEMGVEICPDKLHLCPATADCCEKEDGKWDCCQKTTANAPNNIFLGAGNAVTNWVSSGIAAPPLAPKCKWWGCWFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SRV9</accession>
    <name>A0AAV4SRV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_641421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009758">
        <property type="protein sequence ID" value="GIY34353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SRV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17433" checksum="6224B9409C37D10E" modified="2024-11-27" version="1">MSSLMMKDAFFPTKISPTIAAQKEINQRTGTILSAWLIYLPNGSNTDIFFQLLNIERVSMNGWSFYDYGANFYLDELMDGTRNLAQIATVGLTYGRDTFCVKHSVIHFHGGGYKSEQSLTTQCVSMDDLARKSTWRNIYFIYSCIYVYVYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSB1</accession>
    <name>A0AAV4SSB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_486481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010020">
        <property type="protein sequence ID" value="GIY36196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14188" checksum="EAAABACBB8530CB2" modified="2024-11-27" version="1">MVKKNDKGIEHRLSQRWKRENDKGIERTLLFFRSTNCLNSGKEKIIGNRKNTCVFQEHRLSQRWKRENDSGIEKHSCFSGAPYILRGQEIFSINRIQAIQGYAKHMRPCHYLAAKKGNAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STS7</accession>
    <name>A0AAV4STS7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_110521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010062">
        <property type="protein sequence ID" value="GIY36561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="14063" checksum="D0735657B0F70112" modified="2024-11-27" version="1">MSQVHLFYSFYSHEPKGQTIISNLRISFFQLHPSQLRLRNLLYRDLQFKSCDLSPKNLHISIRDVGSLSLPFRNVLFYALLRLRAHEKLSREKEHRVYVAIRFSIFLSDLRCGKTEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STY4</accession>
    <name>A0AAV4STY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_358511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010054">
        <property type="protein sequence ID" value="GIY36474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15609" checksum="BC8C9587EFD47DDC" modified="2024-11-27" version="1">MANKKLSLKNSQDSIVLMRIQLESTKFESNFESTKFESNSNQPCSSPTRINLVRVQLESALFESNSNLPGSSQTRINQVRGQTRINQSRVQLESNKFGSSSNQQNSRRTRPLCRQYYSPEMILFMCRENKFFKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TE53</accession>
    <name>A0AAV4TE53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_497951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011022">
        <property type="protein sequence ID" value="GIY43746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TE53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15130" checksum="83D50FD5040632FC" modified="2024-11-27" version="1">MLEDCTVGVGVEYILEQIPRGGVGWAAHFIPQTMHFHIRAPTSILWDVINSVELFNDMEALCCPLTFISWCGVGIYSGTDSARGGVGGSSFYSSNPCTLPIRGTDSILWDVINSVELFNDMERHYAVHSHSFHGVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TER6</accession>
    <name>A0AAV4TER6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_80471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011239">
        <property type="protein sequence ID" value="GIY45143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TER6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585:SF1">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585">
        <property type="entry name" value="INTEGRASE CORE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="1">
        <location>
            <begin position="87"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="15143" checksum="A4079B302FF5CCAF" modified="2024-11-27" version="1">MENLYNDIVEPNIKHSSFKLNDSVRISKWKDRFEKGYKNNWSREIFTIHQILPRQPIVYKLKDLKGEIIEGTFYEKEIQKVTDSGFYPIEKIIKKKKKKDGKVEYFVKFLGYPEKFNSWVSSVKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEV7</accession>
    <name>A0AAV4TEV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_50597_1</name>
        <name evidence="2" type="ORF">CEXT_466371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010854">
        <property type="protein sequence ID" value="GIY42498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051333">
        <property type="entry name" value="CLIP_Serine_Protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260:SF136">
        <property type="entry name" value="GH08193P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="1">
        <location>
            <begin position="31"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="300" mass="34085" checksum="3445F9C5E8B3D2A9" modified="2024-11-27" version="1">MDNYMDLRTVMDTIKNKEQRPKRINPARCGYIKHEKNYLKHWTWLAAVYVNSPDKYNATSLQFCSGTLICGQWVITAASCFYHTYQNNGTEEFKRTTEAMFVVLGEKDLMHENRNQMNFYAEGVFIHPDFRAPDGLEHNLALVKLNAPAPPKRFRPVCLPPAERPILLHLELNINVSIAGWGLPPPFDNEREVTGGTVRFRSSNISVALETEDRCRMHDEQQPMSGSIFCAGGLGMQTCIGDLGSPIVAVDPFTNIHHLIGVLTRRSKCQQGINQYTELTRHLKWISDTIDNCHSIHANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVG5</accession>
    <name>A0AAV4TVG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CACNA2D3_2</name>
        <name evidence="1" type="ORF">CEXT_329591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011846">
        <property type="protein sequence ID" value="GIY49506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="20543" checksum="B6FAB9938EB5B9CD" modified="2024-11-27" version="1">MEHPILLKIYLGDIAIQIYQSVFFYISGKKVTESHEVNWMACANKATALTADDNSCYSVFDRRNTKSTNLLGVAGTDVPIREVTKLTRDYKIGFPDLLKPGYRNVDLTEVELVDSDTGLYEFNEALLTKIILFFRLSVALLEPYGHYRVIGQIEVKRREEDWLEYFRGQNWKVHPDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U112</accession>
    <name>A0AAV4U112_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_551921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012101">
        <property type="protein sequence ID" value="GIY51402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U112"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11201" checksum="80FF16C78D66744F" modified="2024-11-27" version="1">MPLGIPELMLFPHDCKTDFPLSCNIKRNLYSVMSVMRRTRKGKYMQTTLQIRIGREQFTVWHVNGFQNRRVSSTWGGVGSKERKKVYFVHPMHSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6N2</accession>
    <name>A0AAV4U6N2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_236531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012341">
        <property type="protein sequence ID" value="GIY53280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6N2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10831" checksum="A41DE4870926A7B1" modified="2024-11-27" version="1">MFLKNNNKGSCEKPKLDGNANWINVKSELLGTLNVRCLCTSCTRLIQQTAFDKHTIPSNRFLLNQGTDESQELLLTLEFPLASLKNWSSVESKCGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8H2</accession>
    <name>A0AAV4U8H2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_597141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012462">
        <property type="protein sequence ID" value="GIY54048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8H2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14876" checksum="EE2F4F0CF78B587B" modified="2024-11-27" version="1">MTLKKFRSHSKEPAETANRRTLSRKYIFVFPTFESASNARCSSIDKRDWNSWKEGKEKKKVLEGDFPRTDTPTITLQNRGRTVSSLRKGPLNVNTQLWGGEGRGPESGPRQKREGGEWHYLFSGSSLRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8V1</accession>
    <name>A0AAV4U8V1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_98021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012475">
        <property type="protein sequence ID" value="GIY54151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8V1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14965" checksum="AFD314EF6EA281E8" modified="2024-11-27" version="1">MHYTSRRRGRKPESQVVRLLPHDPSNCSADGWRLLLLPFKLFILSFLPPTPPSSSRPENGGRKPESQVVRLLPHHPSNCSADSLLTSRCFHSHETFPHAYTIPTPLRNLLLHSPLSTTPDGGFIFFFHLSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U915</accession>
    <name>A0AAV4U915_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Solute carrier organic anion transporter family member 4A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SLCO4A1</name>
        <name evidence="3" type="ORF">CEXT_615601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012485">
        <property type="protein sequence ID" value="GIY54227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U915"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF159">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 74D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="497"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY54227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="604" mass="66647" checksum="7F8FF01B2B144881" modified="2024-11-27" version="1">MPQTQTQFHMRAATTGDSNVPHLHTILKRRRSCRLKAPILNKDCNVPAGLCRVQKHSPLEETGDPSSYHLPYGLKKLKKNDSRISSSNTGLSTPVVTPSKEALFSSKQDQCEERNKTGAHTRTTQTVLIIFFTSLLLIGIGATAVYTLGIPYIDDNVATRESPLYFENTEITTDNPQWVGAWWLGVLFVGASLVLTAFPMMCFLKNLPKSPKACLHGTKEQKNLNHNGNKIVKCNGNAPHPPPQANGTDHNQCQTCQHNYYDQKEELNKPSLRAIRRLLKNEILLYRTASSVLHILPIAGLYTFLPKYLESQFHLTAAMANMVSGIAGILVMGIGIFASGSYMRKFKPNARFVARWIAASAALYAIGMIILMVFGCPLNRYVGLNAGSGYEDTTQMSCNATCSCKPGEFSPYLHQRRSNISVTLLSWLHTGLWFLLRRDCLCLGANVTATNGFCQLQCNNLLPYIFVFAIFVLVHSTSEVGSMLLTLRCVEPKDKAMALGLIAFAIGLFGNVPCPIIYGAVVDSACLFWEDNCGEQGACRLYDPSKFRGVFHGVTAVIMSLAFCVDLIVCKKAQSIQFQDEDEAIDVEETVPFNETSAQSESSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UA77</accession>
    <name>A0AAV4UA77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_414161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012537">
        <property type="protein sequence ID" value="GIY54658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UA77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9912" checksum="5F4209C79EFFCC83" modified="2024-11-27" version="1" fragment="single">MAGTIKEPDMSLLLRNGVAWSAPRTSAFIWRIARDVTRKDSHDVFAFANGIARTENRILLASTRIISRTVEDLFPELPPTKQMETVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJ36</accession>
    <name>A0AAV4UJ36_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_478321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012957">
        <property type="protein sequence ID" value="GIY57762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJ36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="17025" checksum="277D02F4A648E0FE" modified="2024-11-27" version="1">MGAMDIYYIGGKDLWDIYYIGGMGAMGYILYWRYGIYGIYIILEVWDVYYIGAMGFILYWRYGSYGIYIILEVWQIWDIYYIGSMGRILNWSFGVYIASMGCLLYWSYGMFITSELWDVYYIGAMVWLLYWSYPVDEFSSQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJI3</accession>
    <name>A0AAV4UJI3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_434821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012980">
        <property type="protein sequence ID" value="GIY57869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7643" checksum="132CE832B76B6DE0" modified="2024-11-27" version="1">MSKSKLSKPLYPTAWVETVGNRESSATQNSPFSPNIIEEARFRCDGSQSFDIAGRNSFGRLNPVTSETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKD6</accession>
    <name>A0AAV4UKD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_158721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013045">
        <property type="protein sequence ID" value="GIY58300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="292" mass="32743" checksum="E6BC42F181790537" modified="2024-11-27" version="1">MRITYRHNNFPKLIPKSTSSSSPRHQLLPQGTSSSGSTSSSPRHQLFWKTPSPRHQLSGRQHLIPKHQSSPRHQLFWKTALLEDNTSSPSTSSRQHPQGTNFSGRQHLIPKAPALLEDKHPFISKGTPQLEDNTSSPRHPQLFWKTTPHPQGHQLFGRQTLHLQDKDTTSSTGRQEHLISYSTPQLEDNTSSPRQHLNWKASPHLQGNTSTGKQHLNWKGTPHLLFNASTGRQHLISKATAQLEGDTSTGRKHLLLKATSHLQGNTSTGRQHLNRKATDPSNHPSILDQSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URE3</accession>
    <name>A0AAV4URE3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_193961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013278">
        <property type="protein sequence ID" value="GIY60109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000744">
        <property type="entry name" value="zinc finger E-box-binding homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY60109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="42074" checksum="0863412ABDD287BC" modified="2024-11-27" version="1">MKTFGTLTTKQLYLYKSILKSFENPDSIFGNNPQEIPATISHSAEGADFNSLAFTNRTSTLQSSTFSQSTDQERHWDVNSTASTDVRYASSNAVQNENFNYFNSSQSIFFPATQHFENSACTSGVENLKMPFFNAVYTSELNPVQQPRTNNSAFTQRYPNLSFYNQLPPDSPGPSNVLTKYDLTIENFNIWRSMESGKTGMPDFKISRFQEKEYDAVAIARKSNRTEKNKSCASHLNSASLNVQHHGNRYKEKKSRKKIHPCHKIAEVCHESSAVELQKIRKPICEGFSCNVCSKKFPNQSSLDKHILTHTGEKPFPCKICGKRFSLKGNKNVHTLTHYGIKRFQCNTCGKSYTQNQNLLRHKQEHLTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3A3</accession>
    <name>A0AAV4V3A3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Synaptophysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SYP</name>
        <name evidence="10" type="ORF">CEXT_461</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptophysin/synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013873">
        <property type="protein sequence ID" value="GIY64394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008021">
        <property type="term" value="C:synaptic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001285">
        <property type="entry name" value="Synaptophysin/porin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10306:SF17">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10306">
        <property type="entry name" value="SYNAPTOPHYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00220">
        <property type="entry name" value="SYNAPTOPHYSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51225">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="9">
        <location>
            <begin position="37"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY64394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="30074" checksum="E6CCF505789FDE5C" modified="2024-11-27" version="1">MVIEVSKEIDVVRIGIDRYSLKTGLKLRSVMDVSIQVIKEPRGFIRIIQCLMAILAFSTTAGFSTECKFSINCGGDEDDIDVEYEFGYPFSHTELEIPHDCDDKELLHMILPFNYSNASGFFVATGVISFMYTIIILTVYIFFHQTYSNNPKLPVVDLVISVVLSIFWMAGSSAWAQGVTDLKYYLHPETLFQFLFICLNEKNGHDVCDSEEDGSYGTLNASLILGFANFLLWTCSLWFIYKETVFHSPEESAPPQNQSAVKGVGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3V1</accession>
    <name>A0AAV4V3V1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tyrosyl-DNA phosphodiesterase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Tdp1</name>
        <name evidence="11" type="ORF">CEXT_758471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013905">
        <property type="protein sequence ID" value="GIY64651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3V1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019406">
        <property type="entry name" value="APLF_PBZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10283">
        <property type="entry name" value="zf-CCHH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY64651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="33056" checksum="16FB130D8EAE80B9" modified="2024-11-27" version="1">MDSDSDRTIDSDELDEIIRQSQSSTDASSSNNTPKKGQRRPSFHDLSDTDSDDGIVKKKQKLTKASADCPKCEYGKSCYRKNPEHFKKFDHGEENKESKETISPPKKKINKYDIKNKKERMENEPIHKKSPDLNSEVSKKKKKMNDNHPKCVYGKNYYRKNPDHIKEFDHGDEEFEENSSPVNEKTSSIKSQKLLFPRCPNYQFFLTKVSGIPQKHNMLALDIKDLLSFKDVTLLSSAQFNYMFDIEWLIQQYPEKYRSCPLTIIHGEQRESKKALEKSVSKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7K7</accession>
    <name>A0AAV4V7K7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_397561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014050">
        <property type="protein sequence ID" value="GIY65926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052445">
        <property type="entry name" value="ZnF-G_patch_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17614:SF14">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 8-LIKE ISOFORM X5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17614">
        <property type="entry name" value="ZINC FINGER-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="G-patch" evidence="5">
        <location>
            <begin position="40"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="424"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="492"/>
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            <begin position="836"/>
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            <begin position="251"/>
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            <begin position="1892"/>
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            <begin position="1908"/>
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            <begin position="1919"/>
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    </feature>
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            <begin position="1939"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY65926.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
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    </evidence>
    <sequence length="2060" mass="229911" checksum="60330D6D7B69086F" modified="2024-11-27" version="1">MSERYTRFHEDRDYESKNIDSYDDGLLELEQSSMTQPISQDNLGYQLLQKQGWSSGKGLGRTEQGRLDPLPIVMKEDIMGFGRLEMEMDYAEETTEKRRVLETEKQDTVELQQKYKAKQEKDKAVQEGLAVLKANFFCELCEKQYYKYQEFDNHINSYDHAHKQRLKDLRQREFGRNVVSKWKREDKKKEREAKRLHELAEMRAQAAEMRGPIEMGTGEKFIPGGGFKTIGTEELSEDISQKENSYSPTHPSEDEPSEKSFRYYKKDQIDSTTSVPTSNTDSDTSSNNKESTLKDLKNDNLKGGKIEPSDLFMNIRFFSPNDIDLPPLPDLPPLICPSTRKEEESSTKDVSDLLLPKVKPGFVPKSVVLLGKALARKRLMAFSQVRSSEGNCSETSAVKSSPALSFSLARKASQKLNAGVVAAFKEEEEEDSKDSKDSSVENVKKEAAAKKNTDANSTTSKTEVYPSQPPEAFTKKPNFGFLTFVKTGVIKGSEKETSENLSEKKEDANQSEKTSKYRKLDASSSSRYYEDKAWSRDRRRSRERERTSHRYDRDRGRRRDYHDRKPSPSRDRHRRYERDRRYYERDGRSYDKDRRYYEKDRYRKSPGGEWRQSPGREKSYKDEEDKNRTYPKTVEVDHVEELEKMEEKSIKIAERSEEAKDESVQSKDEKETMQIVPDVDNNTNHNLSNFPHEAFSTTFVEVKENSPDQKSADFCDKSIINDGNKNRIQSDLTENLTSQTNKIVFSNAKSNDLFQSSAFNESIALSEKDKKFIETKQSDLVNSDKALCINECKKETCTNISKDKTVLNDALCKNNPASPNKVSETTKGAQDIFVEKEMAKEPQKSNVKKTEKKSASVSKHQDSGSSKKKEDKLLAQMLKHKAFKKLCKETGVDVNEKSKKFAEAIKAMYKVMFTKKKKRSKKSSSSSSSSESEAESSDSSSSSESDSSSSTSSESSSEEVDLKKPRKKKAAQKRKSHKVSEVTSTNAIVEQTTEKQQDVEEKLQSPNPEEETIQNSNELSEEQNALEINLEKTTSNGLPQQKLNIQESSKVPIVSEKAVASEEDGIGEEWNEDCSVPVDEAKLNSKEDNREVSKKIEKRKHKEICDFQAFEESPKKSKPSLESFTYDRKPEKFFMKWTSTKPFLAYCINRTHRTSECIPEQSSSTPEKSHSDNDPSRADSGSLSALDALKVSYSQTQVTPTNLLKRHSESSVDVPSPKRKPSKLMESQSNLLPVTKAPEVEPSPKVLTRVQNEVQSEKISKGKVLPLEIKSEWDTDSDNERSNMDWSPASHENSILQLSAEQTDADDLESNQLQVTKAALIENKSENTITSSEPNCMTVESVSLSPEKKSVSMSSEPAQCDVQCLQNKSVPSEQNTSEISNPKGNPEISLKTSLVPEVMQPESILSVSAESDRVHSSDLDSEYDEFLKLLSLSESQTKLLNQATNSQKREIMYPNSVNVKVELFSSTKNNNSKVVAEKTEVLNFFDTPVFQSKNVMDETNHKKILCASSFSNEPKIAVHCIDREGNLKQAQNQNVIHEESSMEFSEFSGSSIANNSVVQDINETNIIPVVYRETDQNTRGKEEMTSFKELESKIHNLVKESSETKDNSKAGLSDMLNLKSVLDSTVKNPVSYPVGVFKNSGQITADNVLDILQNLGNHSYDAQSGPLEAVTENNLNETYLKNPVKVVSEEDVPYLKNPVTVVSEEDLPCSKANNESFQSSQETQADASKKAVEDARSEIASILNNPLSIEAYNISKTYIEYIQQMQKASGSAVQLQAFQDSDMSKVLSQFMSINSALLEADRIVSPQDKAVSSSVMDAATFDSTPEAVTSSAGTSKKRKHRKSGTPKAGILVMPSRDSQPKKSVTFADGIPPTKDLFVGNISPPPPPPPPKERRHKVKVKHLRRGERPSPPPPPPPPSEVVIPASSAPAPGQAQDERCSCATSTSCSSTTSCTSSSSTTSCTSTSSGSLPAGGAAGALWPGLHRAALRCLLWQLSAVHRGTTGNAAPVPSLPASRYPDVRPLPLSSSRPAARLSHAAAAPRSPATAAAAVISCTITHIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VG89</accession>
    <name>A0AAV4VG89_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_701031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014522">
        <property type="protein sequence ID" value="GIY69337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="GIY69337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="15650" checksum="6201CE9EC30B11D6" modified="2024-11-27" version="1">MNGREPTRLKRSSTLQLDKDIRSRINVEHSSLDFAQEPLFPRKPPSETKFAYTDGFSDKFLNKGGAGIFFLPPNGSKYHHKRNTGLIASKFTSELVAIKEAVALYLNDSNILGLTDGKGSQPEMMSLNVSTDMDGLGRGSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUX4</accession>
    <name>A0AAV4VUX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_193431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015189">
        <property type="protein sequence ID" value="GIY74245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9283" checksum="2E40590E32EF8904" modified="2024-11-27" version="1">MNAEISHACVRGIGVATVKSVFFHIPVSHSGAGQVTTNLEKAISEFGIHPAVNYGIVGGVAHGKPVTDEPNVDNVFVLPDPRLGPRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VV49</accession>
    <name>A0AAV4VV49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_629651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015205">
        <property type="protein sequence ID" value="GIY74346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VV49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15275" checksum="43E998ACC4F388B5" modified="2024-11-27" version="1">MDYEDCHENLSDAEPDSDHEDMDDAQKLLGTWLGELENLKLHITILFHNKKTKQNSPCSQIDLRRLSFYIKISLFHTNEKTHRFRLSRAQHKNPIPVCFKRSWRSVTFPDCVSTATHIFQSSLLLSVFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0Z0</accession>
    <name>A0AAV4W0Z0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Multiple epidermal growth factor-like domains protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Megf6_3</name>
        <name evidence="9" type="ORF">CEXT_111511</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015472">
        <property type="protein sequence ID" value="GIY76322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.300.10:FF:000002">
        <property type="entry name" value="Multiple epidermal growth factor-like domains 10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.300.10:FF:000041">
        <property type="entry name" value="Tyrosine protein kinase receptor tie-1, putative"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.300.10">
        <property type="entry name" value="Tie2 ligand-binding domain superfamily"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042635">
        <property type="entry name" value="MEGF10/SREC1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043:SF8">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="63"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="282"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="330"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="373"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="454"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="631"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="669"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="8">
        <location>
            <begin position="848"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="882"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="864"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY76322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="936" mass="98811" checksum="982D45F820123FCB" modified="2024-11-27" version="1">MSGSHLGCAYPGACVRGTFGPGCMFNCDDCQNGGKCDVRAVSCTCQPGFTGLLCNETCPKNTYGQGCTKKCKCHNGGICDPATGECICPPGIQGKKCEDGCPPGKFGDKCEKNCPQRCPSGRCNKIFGYCECDAGLFGPKCNLPCPDHTYGPNCRSQCKCVKEHTQKCNSKTGKCECKVGFTGARCETVCPPNRYGETCQNTCNCPTGTVCNPLNGECLKECPPGFNGTNCEKGCPDGYYGTNCLKICLCGLRECDRVTGTCLCDAGKMGPQCTQECPPDKYGQDCKNQCYCENGATCDRVNGRCHCSAGWTGTKCHQPCSPRSYGPNCQNECECLHGGECDRFSGECICPPGWSGPLCEKPCILGKYGENCQQECQCENGATCDHISGACTCGPGWRGTFCQIPCPAGFHGFECNQTCDCGHGISCHPETGVCHCPEGKHGDKCLKTCPPGTFGTSCQENCLCQNGAICDPINGTCYCSPGWHGNTCQSACPSGTYGLGCEGGCLCKNDAKCDPRNGRCECKPGFKGQYCAKVCEKGRFGHQCSQMCICGNDQPCHHITGQCSCPPGKIGKGCEKTCSEGKFGIDCKENCTCPLNHQCDPVDGQCFCRLGFHGSNCDKICSEGNFGINCSDHCNCEHGANCDPLTGTCICPPGFTGPTCAQECPTGYHGDQCLKTCHCQNGATCDPKTGQCVCPSGLTGQFCEEACPVGKFGKHCKEKCNCENHKCDPKTGKCLCSPGTTGLECAEGCPQGFFGPNCQLECQCKQNASCDPVTGCCHCPSGFVGSLCEYECPTGWYGKSCFQQCDCTGTALCNPVTGICTCPAGQHGIKCEKACTQGFYGHGCQEECNCGNHSCDPTTGKCHCPPGFTGPQCSEICRDGKYGPGCQQRCQCQHGGTCNPTTGKCTCPPGWIGSTCDISNGSLYGTDEDGITNGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W1Y7</accession>
    <name>A0AAV4W1Y7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_268371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015415">
        <property type="protein sequence ID" value="GIY75904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W1Y7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="254" mass="29836" checksum="7862628F5E908F91" modified="2024-11-27" version="1">MQPLQGRLIVSISAVIITVCVCRVMSGYLPIEKCDELLPEYECECRKAYLKDVALICQNVSDFEAFNDILVEWFCVRGEHNLPDLFIWQHYSAQRVPQWTDSFFPQCRRLPDPGGRRCFRWGTLCQVLLCRKKLYEGDSRLPSHPQLPADLGNGQQPPYPAERRQPQEPDSSLETLLRQQFHRQRGRRRLSENVTHFDISHNLLTYLPPSLFRSWKRLEVVRLSYNQLLHVDHLFFGTNPEVSYIFMSLLWILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4W0</accession>
    <name>A0AAV4W4W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_387661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015600">
        <property type="protein sequence ID" value="GIY77293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9419" checksum="7921AC6811A31D69" modified="2024-11-27" version="1">MGKNRTDSQTLCLSVFSGLNTDHRLPNMQSDSDEKAAEMEDALSSTRVANYQSTGASKRSPKEPQGQVNKTCLKCFSCIYKNALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W735</accession>
    <name>A0AAV4W735_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_785081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015769">
        <property type="protein sequence ID" value="GIY78567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W735"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13040" checksum="29EB35E6C35EBAD7" modified="2024-11-27" version="1">MQLNKFFNENNHRIIAPTSATRIDSRYNAHNIIDFAKFKNIPFPATAAVFHELSSNHLPYLLDINLNINPQTIPNLFFTNWDNYNFNLQQTNLKLININNEEDADTAIENFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8H3</accession>
    <name>A0AAV4W8H3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_657581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015731">
        <property type="protein sequence ID" value="GIY78226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8H3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10460" checksum="1A994783E1C9A99D" modified="2024-11-27" version="1">MGKGQFKVTGSEALLRTIDARVIKTSAKVPQDYGLKHKHKIYDPRTNEKALVSSLLPLSQLLKRRLKKRLPNGKNYFDSSSNPVKPPSVNVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9G8</accession>
    <name>A0AAV4W9G8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_739061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015887">
        <property type="protein sequence ID" value="GIY79437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9G8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY79437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8551" checksum="CDE8EB19B7A38EA6" modified="2024-11-27" version="1">MFNSNIFFTELQEGKGIVLMRGEYDDKTLKAHEAQCLTNQLQLYYGGSDNEKLLLPWKVIKEMFLWQYNQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WAM3</accession>
    <name>A0AAV4WAM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_558241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015937">
        <property type="protein sequence ID" value="GIY79842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WAM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12767" checksum="EB833F04D15D3390" modified="2024-11-27" version="1">MVADLSLQRQIMRWVQVYFFRVYNDESVYNDEQRLTADIPSAFSLQVATEHRKEPINKLAAGSPKQPVRNLISDAKSVAFYQNPVGDSIPGINSRPGTICCAPSAGTMESGYLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBM7</accession>
    <name>A0AAV4WBM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lupus La protein homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SSB</name>
        <name evidence="7" type="ORF">CEXT_784881</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016004">
        <property type="protein sequence ID" value="GIY80365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12291">
        <property type="entry name" value="RRM1_La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014886">
        <property type="entry name" value="La_xRRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002344">
        <property type="entry name" value="Lupus_La"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08777">
        <property type="entry name" value="RRM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00302">
        <property type="entry name" value="LUPUSLA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51939">
        <property type="entry name" value="XRRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="5">
        <location>
            <begin position="50"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="163"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="XRRM" evidence="6">
        <location>
            <begin position="263"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="362"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY80365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="436" mass="49928" checksum="12EC6D557DB1B6C4" modified="2024-11-27" version="1">MKWSDEFRILARLPIMGTEDLSTTAESGKDTSELQKKIIRQIEANSSCLSIPSDHEKLTVSLAMNDSWSKIFIHKKSQLWLELSQTVDSLQGFYTEANWGTLEVMVKFNRLKSLSQNFEVICTALSKSPNDLIEVSEDSTKIRRRVEKPIPDSTSVHDAMEERTLYVKGFKKNNTLDELLDFFKDYKVEHVTMRKRFQNNNRTFKGSCFVLFETVKDAQDFLDNKNIKFEGTELLKEKRKKKKKAKNKKEDENEKNKEVPEIDIIPGCLVKVTELSKNLSREDIKDALAEFGNISFVDFFRGQPEAVVRFETSVAANVLEKAKEEDGVKKFDIGSCKAIVSVLEGDAEKDYWKTIAISRANRKQKFPNQKGKGRFGKKNFGKRQKGNREDDRNQPPSKKSKTDSKEDVSECREANGKDNNTCMEHNEAEKATVEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCA0</accession>
    <name>A0AAV4WCA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_346191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015921">
        <property type="protein sequence ID" value="GIY79685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10971" checksum="F05664200B966C66" modified="2024-11-27" version="1">MGNLVFSFTPGISWKFVAHILRWNLSNRIQRIGEINNLDCKLYKKRWFPMSSGYSSQRILEINNLRYQCASGNKSLHYFAGTPDNELWIRNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCI7</accession>
    <name>A0AAV4WCI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_805521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016016">
        <property type="protein sequence ID" value="GIY80517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17472" checksum="35676560CFEBD6C8" modified="2024-11-27" version="1">MISSLEPTTDTSSSVLVFDPLGSLVAWTIIEAVAVRPHQAAFKSLHHNYHHGYHKPYLILHLYSRDILRLFFKDILDLSGVDDFDRRQPYQNSPPLTEEMLQQMIGIPSSSRIPKIIETVNYTSLSMMEESWNINKEAIQTILLEDLGKTSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFJ6</accession>
    <name>A0AAV4WFJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_316051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016103">
        <property type="protein sequence ID" value="GIY81296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10452" checksum="3817CDA5A390D944" modified="2024-11-27" version="1">MVDADESTPEFMLRVTTSRITDTIDNSPSIANQSRYVQNFGGRFVRKRFPQSREEFLPFSRLPILRVASDEATRYHQNITDRNVLSNDPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGK5</accession>
    <name>A0AAV4WGK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016190">
        <property type="protein sequence ID" value="GIY81996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9917" checksum="C4A8D03FF3AF1B11" modified="2024-11-27" version="1">MLSSMNFLKLVIQNRDKTVLRLLHSPDVSAEHELGVFSSFVIFNSAVTTTVSFILRNVILQGFKRTSTHAHLQTQLLSLLTQNGELYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPT0</accession>
    <name>A0AAV4WPT0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DOLK</name>
        <name evidence="11" type="ORF">CEXT_671701</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01016396">
        <property type="protein sequence ID" value="GIY83535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004168">
        <property type="term" value="F:dolichol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043048">
        <property type="term" value="P:dolichyl monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY83535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="413" mass="47161" checksum="36CEFA5FAD760215" modified="2024-11-27" version="1">MEYKIQTNAGYGFWCYILLLFCLFPFMIRNGPGIYTLLFNVCLCCCLTPVFKENPRKINSWFRENFPIMMLSLPPSLFMSYFLLTISYLLIPHVCLVFCIIVICVITLLSKLHAPFNFPIMKAIPESVLCLQILLLGTFLLVHVLCISPNLRQGIKFFFCCIIFSCIMMLMWQVILNKNIFVWICLYCLRDRKRVFLLLWWLMSTFAAVIFVVWVNRKPNYKASTLARKYFHLIVCVVYIPGILYDLDFLRLASGIALTAFIVLEMFRILKIPLIGPAIEDAFRVFLDEKDTGVLILTNIYLLLGCSSSVWLAGVKNGIISVGLGDTAASVGGTFFGKHHWKSSKKTYEGTICAVIVQLVASLYFLSIGHVWSTFNIVVVILAVLFTSLLEALTSQVDNLILPLFMFSFLCWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQ44</accession>
    <name>A0AAV4WQ44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_55931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016511">
        <property type="protein sequence ID" value="GIY84413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQ44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8722" checksum="D971ADF29DF0C8FE" modified="2024-11-27" version="1">MVRRCTNKIKCSQCQRRHYNVMCPELKQVVSTGSDKLVAKAVENSNGKFHTLANPTCSADVLLQTSIVYLYGNDAIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQZ9</accession>
    <name>A0AAV4WQZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein masquerade</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mas_6</name>
        <name evidence="1" type="ORF">CEXT_671381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016616">
        <property type="protein sequence ID" value="GIY85122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14194" checksum="C164B2F0FA13D8ED" modified="2024-11-27" version="1">MLKTIYISNHPQIPLIRPGSQQQGYPNIPLGNPNYGPQKNQQPASPFIHKYRKISFQEKPVPPVRVQHIPNQANANQGYVGAGQTGYGLLPQMPHHGNNGYVNPARKPLKTTIMGLTIIKISSQTTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRE6</accession>
    <name>A0AAV4WRE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_384311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016636">
        <property type="protein sequence ID" value="GIY85272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043741641" evidence="2">
        <location>
            <begin position="20"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY85272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15099" checksum="ADE82DF0D92888BE" modified="2024-11-27" version="1">MGLMAEWLALWGSVPQVSDSPPSGVMDVCSETDCRRTLSTRTRRIKKQQPPPKTKTPYKSNFQSHSLFAHFCTKASPAKLKTTGRRSPNKPWDCYPGTTSTQTTGERRRDSGTAEKWRMIRRNPADISISAAAGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WT98</accession>
    <name>A0AAV4WT98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_469341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016584">
        <property type="protein sequence ID" value="GIY84870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WT98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16185" checksum="11FF2F00F7AF4A02" modified="2024-11-27" version="1">MRSNYNKHFMKLPFCYIKKEEKDLTVDFYDFFKNHCCWFHVTSLIFKGGRSRNGLSHLFRAMAKEKPLIFNKRSGAEREEGLSSACAAKRRTCSRRGSASCPWNVISLPFLRVQRGKVIAGHLLGSHDPPHSCRCLQEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WX44</accession>
    <name>A0AAV4WX44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_334481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016850">
        <property type="protein sequence ID" value="GIY86843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WX44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8209" checksum="C7AB0E946E2D7C7E" modified="2024-11-27" version="1">MSGRCSFCFSSNKVHLKGIEFLLKVYVEHVTSKRTSKLVINDSKTVSLIWRLSPGQPKNIMSDQTGEAIACEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBQ6</accession>
    <name>A0AAV4XBQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_472931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017389">
        <property type="protein sequence ID" value="GIY91219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13144" checksum="0694CE21C6C4D03C" modified="2024-11-27" version="1">MSPYEDIFPFDDPIEWVNQVKYLGLILDSKLTFRKHHHTENESSDGSEAKAVDSVMGGSSAMACGRLDALPPSRRRRKSTASRSRGRGASHTVAKPRTVAEGYPSCLKIPIMKRRNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFI5</accession>
    <name>A0AAV4XFI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017711">
        <property type="protein sequence ID" value="GIY93837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8728" checksum="DA2FEDFA9CA72513" modified="2024-11-27" version="1">MKGISARLLTQKPCSLPRRIVLSFPPPLYRRWGDGLEQWKAEKKFIFGGPTGNSKKKRQLPCSIEPFSFTRDSNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG80</accession>
    <name>A0AAV4XG80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_613631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017683">
        <property type="protein sequence ID" value="GIY93639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043708313" evidence="1">
        <location>
            <begin position="22"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18344" checksum="033415C6B1863F42" modified="2024-11-27" version="1">MAQASLSFLWTIDILPSPAGSLFFGLLDICCVTSIENAKTSHVSNYGYIVRSILFVVACLNPSKWEGTQIRKPEQATPGSKGRESPIWIPFFGEFIVQNYGCDIDINVEDPPMSASFSASTSLSRNEKHFCYYYPASFQLNGFAKIDDSPVREKKEQSNFRAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGA7</accession>
    <name>A0AAV4XGA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_339741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000295">
        <property type="protein sequence ID" value="GIY93703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9892" checksum="DF3D009C771F99FC" modified="2024-11-27" version="1">MLSNSKKNILKKGEVFMTGKKPVSHNARPRIIGRVVLIHVVVFVWVDCCSRVGIVNVEYPSLCKELFICTLLVGRTLRNHCENTIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHS9</accession>
    <name>A0AAV4XHS9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Single-pass membrane and coiled-coil domain-containing protein 4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_547841</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017818">
        <property type="protein sequence ID" value="GIY94731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027960">
        <property type="entry name" value="DUF4519"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34644">
        <property type="entry name" value="SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34644:SF2">
        <property type="entry name" value="SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15012">
        <property type="entry name" value="DUF4519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY94731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11247" checksum="3DCFFE2C100699F7" modified="2024-11-27" version="1">MTLLVVTPKCRSTGANASKHIYLLTYVATTNLESKKTMRQLKGKVKESKKEKRERKKDFAENKRRFFTVALPIIILLIAVLLFFIYTNTREKRKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XI21</accession>
    <name>A0AAV4XI21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_6135_1</name>
        <name evidence="1" type="ORF">CEXT_801631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017680">
        <property type="protein sequence ID" value="GIY93600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XI21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="369" mass="42198" checksum="217AEF90FB6EBE05" modified="2024-11-27" version="1">MGCWFQNHNGTFWVVYCSPNPSGHCHCHWFMGKGTSANDLYSEAPCELHPLSAYKDIQGNIWGVGNGNLWWFNATNLSWSLLPMPNHTSSSGPWKVACVDPRRYTKMLPGALMDFFFAADPLKETLYLLDASEARWTIRDDSQVIPYVNWSTPYGIINAWDGYNGEYIMVGKFGGNYRVMYTNASEIDWVTMSENNSSSLWPDFGETGEGHSLAWKMGSDHLWLWKEDKGRKELWSFGYKSNKWQRGNRAFESKLPPLDNVLTGWENGKRYCILKRSSDCTSQYAMSQIECWTEAEILPTKSESENLVQSPRLTTISTTIQPKQKIHSTLKPGKIIMNPTILLLLELSLLQQPQLKFQRPPRKASPNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XI81</accession>
    <name>A0AAV4XI81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_1527_1</name>
        <name evidence="1" type="ORF">CEXT_339751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000295">
        <property type="protein sequence ID" value="GIY93704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XI81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16427" checksum="98D7D2C99B441D2B" modified="2024-11-27" version="1">MCFLDNPELCTGECGEDDQHICPHRKKGQIVLGCEQHSAKSKKTTVREERIKQRKHWEVKSDAQDISLSTDQLNAIALLADSENAERALTVVDTGNRHEIGFVTEASNWSAKHVPKTLPIKRPDNLKMEGSADFTTMHQLDFTEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLL2</accession>
    <name>A0AAV4XLL2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vesicle-fusing ATPase</fullName>
            <ecNumber evidence="3">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">VPS4B</name>
        <name evidence="16" type="ORF">CEXT_745851</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01017937">
        <property type="protein sequence ID" value="GIY95578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19521">
        <property type="entry name" value="RecA-like_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000004">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000043">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000015">
        <property type="entry name" value="vacuolar protein sorting-associated protein 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MIT" evidence="15">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="160"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY95578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="437" mass="49056" checksum="99D4F85B6A58686E" modified="2024-11-27" version="1">MTTSALKKAIELVTKATEEDNKKNYAEACKLYEQGVEYFLHSIKYDAQAEKTKENIRKKCSEYLERAEKIKKYVQKPQKQPVKDTGNTPSSKNNEKDSDSDSEDPEKKKLISQLEGAIVMETPNIKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRKPWKGILLFGPPGTGKSFLAKAVATEANNSKFFSVSSSNLVSKWLGESEKLVKNLFEMGRQHKPSIIFIDEIDSLCSSRSDNESESARRIKTEFLVQMQGVGNDNDGILVVGATNIPWVLDSAIRRRFEKRIYIPLPDIRARRAIFELSVGDTPHELTDKDFKILAERTDGFSGADISVLVQDALMQPVRLVQQATHFKEVSGRSPCNRDIEVHDLLTPCSENDHGAKKMSWVDVPGEKLLEPSFYNDILSSLEKAKPTVNNADLVKLEEFMKDFGQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM79</accession>
    <name>A0AAV4XM79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">39S ribosomal protein L2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRPL2</name>
        <name evidence="6" type="ORF">CEXT_555761</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000454">
        <property type="protein sequence ID" value="GIY94924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF73">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="5">
        <location>
            <begin position="103"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="4">
        <location>
            <begin position="194"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY94924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="324" mass="36430" checksum="55983C1ECACD15FC" modified="2024-11-27" version="1">MSFLNMLSLTVNLQKRLLTDTLKLVARLDPVTVKPEIPLVTQCLDIVRYSRRNERVFRKIRGGGRPVMEGVVPPEPQKYGWRPVLPEDGIYTTRPLPIIKMGGRHPETGRVVVRTIGGGHKKKFRWVDYKREGPKDGSFLEELVVQVRYDPCRTARIALVANGDHKRWIVATDGIKVGDIVKTSSVIPRIPVRPTVGDAYPIAALPLGTVIHNFEMKPGEGGYFCRAAGTSAQYLKKIDNKCLVQLPSKRQILLDGKCMVVVGQVSNIEHGSIPIGSPNRLRWLGKRPRSGLWHRKDGYCGRKIHPPKSILDTLAEKEKKTRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMM9</accession>
    <name>A0AAV4XMM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_518731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000528">
        <property type="protein sequence ID" value="GIY95480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12971" checksum="C518F159B6B07011" modified="2024-11-27" version="1">MSFLGKGRKSDLIEFGTELGVTILPEAVIVSIKRLITSNENYDEEFVKQVFERIIQERIKRQENERLEKENEKQRTFELEKLKLLNESKVMYQTSTEYDTNAPEVTNQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMW4</accession>
    <name>A0AAV4XMW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_724931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000668">
        <property type="protein sequence ID" value="GIY96516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18541" checksum="AC50C47B8EA79268" modified="2024-11-27" version="1">MLCDIVVDKDVYVICKASHSAIQAPLEEEKNERKKTIDIKDLSKLLPLTSLFFFTLQNISQRLQKPRPKTRGPPQKKKKKRHIVAALFTVLLAGDHLLMDKGEFDEINFAYNQNVPRGPPWGSALKPALMRANYSSREQKCALGFCCDSLRLRGRLCLSGALGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNJ7</accession>
    <name>A0AAV4XNJ7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_358061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000674">
        <property type="protein sequence ID" value="GIY96566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="58" mass="6729" checksum="D9341C4298653C44" modified="2024-11-27" version="1" fragment="single">MEGFYFFGSRLVPNNLWAERRTKSRSRLRWPVSADGWHGKTQNPLSCNAYASSLCHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNQ3</accession>
    <name>A0AAV4XNQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CEXT_335431</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000554">
        <property type="protein sequence ID" value="GIY95611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005272">
        <property type="term" value="F:sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY95611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="388" mass="45009" checksum="6861806166F0675D" modified="2024-11-27" version="1">MSSDNTKYTQENIPISLTNSVSEVSSNHEKTEIERASETNKKPGRIFKETPNALRNSVSEVSSNNEKSEIETVSEASRKARGIFKASVVCKIIKYAIFLTCFSFLFQQSMDFYYYYVTYPITTSIVVRNSKIVKKPAITICNHNPYQNYIITQKGSMLSIDELIYESYFNLSQDSPPFIESNSRWTESMQPVLIFDPMLEMHKASYVKCFSSNLHLLDNEYPETQEEEEHLQPAPYPTDCTDYVALWEKNNKTGPRSQENNMSSEILHCIAKHCFSPNKAAWFETRQTTQKEYTRIHAELGRVVSGFSDSCIGKRRKNINECRMNCKPDCVKDVQYPDSASEKDKYSFLWRKRWHVRLSSKLSVDALVIFRSRYHGQKNFMGYIETTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSQ4</accession>
    <name>A0AAV4XSQ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-fucose kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FCSK</name>
        <name evidence="5" type="ORF">CEXT_88061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018104">
        <property type="protein sequence ID" value="GIY96944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050201">
        <property type="term" value="F:fucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042352">
        <property type="term" value="P:GDP-L-fucose salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012887">
        <property type="entry name" value="GDP_fucose_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052203">
        <property type="entry name" value="GHMP_Kinase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32463">
        <property type="entry name" value="L-FUCOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32463:SF0">
        <property type="entry name" value="L-FUCOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07959">
        <property type="entry name" value="Fucose_pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GDP-fucose pyrophosphorylase" evidence="4">
        <location>
            <begin position="92"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY96944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="20245" checksum="49F560D7416F4391" modified="2024-11-27" version="1">MIKYYIIGIITNVIQKKLELYCYNVPYFGICDCNRKRNRIFEEKERIPNDVCVLTIEDPAKNLGSGAATLNALLVAVEYLSAKQNYMVLSSDVLLQSRILIIHNGRDYLYTCTGKAFITLPEEYAPEDKSKPYSSSILSNLESVFQLLNKLSYESPFGVWVCSTDMLISQKKNYVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU48</accession>
    <name>A0AAV4XU48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_104931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018260">
        <property type="protein sequence ID" value="GIY98128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="26777" checksum="789883E85B82F9B5" modified="2024-11-27" version="1">MSQGDAIIVNDGDNDEIDDDLLPPPEVISATIISHSCSPLTLLRVTFSAVNVSNCCHRLLLIPLPSIRVTSATIISHSCSHLILLPANVSNCCHRLLLLPSSSIRVTYATTVGHCCHHLTLLRVTSATIVCYCCHHLTLLRVTSAAIVCYCCHHLTLLRVTSATIVCHCCHHLTLLRVTSAAIVCYCCHHLTLLRVTFSAANVSNCCHCLPLSPSSSTAYFDFLAAPHRRISKEMPFAISDRPSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4K0</accession>
    <name>A0AAV4Y4K0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_600291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001289">
        <property type="protein sequence ID" value="GIZ01361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4K0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="16864" checksum="821AEAEDE2DF8CE0" modified="2024-11-27" version="1">MERSEARGTKGQRASQLPSGHLVLVEIIFNNIVITHNHIGSQCEFPCGPFVQHSSNFPTPMATLFTRFVPIEFIIKDRPMIAELSLSRYNLPDPLTSHESSTAARRREREGGNVTFRACLARAMTSQKPVLSQIRQPNQQAIHLWDVTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6W5</accession>
    <name>A0AAV4Y6W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_144291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001412">
        <property type="protein sequence ID" value="GIZ02195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17953" checksum="BBFCAD984F12899C" modified="2024-11-27" version="1">MNTKSESSDKSRQLNCEDQCQIIPDLRYKTRIKYGTCKKIVPGKLGMRRNYDKLVPRLLTMDENVCSDPQGHMCVIVEKSLSQKLMFEISTLWAFFATLSAMSQQQLKQRVEIWLALIFLLKNASTKKGFQGSFSKRLQKDSFCDTKPNLLTEMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YC61</accession>
    <name>A0AAV4YC61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_425441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001620">
        <property type="protein sequence ID" value="GIZ03561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YC61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15828" checksum="796363B7DBD0D41A" modified="2024-11-27" version="1">MPFPCGNKQFRSNQHQAKKRRERDRQSKDILCRQCNWLAPRHHKTLPFIKSPAKVNNLGSFRSTSVWKKHIIYVLTLGSKVRSKSFGDWEAIDVFFFFFLQLSGKRIQLIDLFFNAQRNRWAIRVVLLSSVYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDV0</accession>
    <name>A0AAV4YDV0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M12B propeptide domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_807901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019105">
        <property type="protein sequence ID" value="GIZ04571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="16346" checksum="8060D4E79BF7E107" modified="2024-11-27" version="1">MNPAEGLLSATFHVLTVTEGASNSSLEFNRAPFLWNCIYEGFVENEKGSAVTMSVCNGLAQKCKCTLPYLYLPTFTLPEIVLILWKSIEMILFIENCRWVTNKHIRVKLMKMTVRLMTIPLHFYGVEIDSCVFAYGYMETCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6X5</accession>
    <name>A0AAV4M6X5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_22733</name>
        <name evidence="1" type="ORF">CEXT_765281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001805">
        <property type="protein sequence ID" value="GIX66599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005312">
        <property type="entry name" value="DUF1759"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03564">
        <property type="entry name" value="DUF1759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18664" checksum="61DC5876406DCBF2" modified="2024-11-27" version="1">MGCVWGQFCRIDEDESIRVEDKFQYLLSSLKSNTKVRVIVESYPPSKENYSKVIEHLKSRFGRKDLLIEVYIRDLLALVNSKTNIKLSDLYDKLGSYLRALETLGVTTSNYAAMLYPVVESCLPVEILKAWDRYRLSREVKRGFYSHEGEGSRKSYVFLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M782</accession>
    <name>A0AAV4M782_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intraflagellar transport protein 140-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_24511</name>
        <name evidence="3" type="ORF">CEXT_533561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001814">
        <property type="protein sequence ID" value="GIX66704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M782"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056154">
        <property type="entry name" value="Beta-prop_IFT140_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056155">
        <property type="entry name" value="Beta-prop_IFT140_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23383">
        <property type="entry name" value="Beta-prop_IFT140_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23385">
        <property type="entry name" value="Beta-prop_IFT140_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IFT140 first beta-propeller" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="IFT140 second beta-propeller" evidence="2">
        <location>
            <begin position="126"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX66704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="23619" checksum="6A506BAE410D16A6" modified="2024-11-27" version="1">MTWAGEGLLAVSAGESSVHLWNVEYGRSTTLSLPSSTPVHQITSISFLESKNILSAGTNQGYVFSWYLMYKEEDDDIIWEVEDILNVSGYIRNFEWCENLEVMGLITTSDVYIISKQKMCFAFDDGISAVQVSARQVVIELVSRDLSVHLLTETEIKAVYLSKNIVALYCNDKLIFYEVNFDDKKTMHLGTFSPPSETILLHDQSVYVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBD9</accession>
    <name>A0AAV4MBD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_438161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002083">
        <property type="protein sequence ID" value="GIX69787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9468" checksum="3F27D544DFB302E7" modified="2024-11-27" version="1">MKSLGKDVVIRLFLIASSNLSTFLEFYGPDKITTVRYKKINYEVKKAHQTKQLDCKRLLTPMLSLHTYPKSWNDSTSVESLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MF06</accession>
    <name>A0AAV4MF06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_632701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002177">
        <property type="protein sequence ID" value="GIX70966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MF06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8508" checksum="CAEE9A13EB19F341" modified="2024-11-27" version="1">MVCWGLYTLLDCNCNLKGFRCCSIFPPPFLAQKKSLQDQRGNSRDFSVLELEMVQPVLVPVGKSSDEWENRNAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGB8</accession>
    <name>A0AAV4MGB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_185891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019746">
        <property type="protein sequence ID" value="GIX71335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12740" checksum="B75E66B42E9D3E95" modified="2024-11-27" version="1">MNRTGRLVRYLITKIRKHLHVLAEEPSLSLSQQNDFFLSYFPSRRWHRICIVCLSVDGFKTSTRAAILDSGKALKKRRIDPGDVLLLVFYYFFSKIFLDASGFLTGNKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKD4</accession>
    <name>A0AAV4MKD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_194281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002363">
        <property type="protein sequence ID" value="GIX72967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043988550" evidence="2">
        <location>
            <begin position="20"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX72967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="27644" checksum="A5FE099E4C2DB174" modified="2024-11-27" version="1">MFCKILYLFIISLFSGSMARSFPRYVVPSQFIYLRPGTSVRVGNQMPPHHEPDAVLINVGGNYPGGSGPAFPPGGPEYLGLLGDQEFSEFSANLEDQEFSANLGDLEFSANLGDLEFRPTWGPGVFGQPGGPGVFGQPGGPGGQPGGPGVFGQPGGPGVFGQPGGPGVFGQPGEPGVFGHPGGPAIFNQPGGPGVFGQPGVFGHPRLPQPQPGFAPGNGGENHVPPVNGFGPGYPGGIHPRPEMPSGGGREVYDDPMSDMFPLIDKTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLY9</accession>
    <name>A0AAV4MLY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_706261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019897">
        <property type="protein sequence ID" value="GIX72979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10453" checksum="0F994331F3DE6401" modified="2024-11-27" version="1">MGLPIRKCLCELIRKLNVTLSKNRMTASPNRNENSPNFESGRRTFLLAAIFIIIISAGNIFEWLTFCQGKLELIFVQLDINCFEKSFHIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MM22</accession>
    <name>A0AAV4MM22_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="9">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">IMPA1</name>
        <name evidence="10" type="ORF">CEXT_187841</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="9"/>
    <dbReference type="EMBL" id="BPLR01002405">
        <property type="protein sequence ID" value="GIX73388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MM22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000004">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000002">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020552">
        <property type="entry name" value="Inositol_monoPase_Li-sen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00378">
        <property type="entry name" value="LIIMPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX73388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="274" mass="29958" checksum="0DC0427FFC8F8503" modified="2024-11-27" version="1">MASSVDLDEYYNVAVKLAKSAGEIIRKAIDKEKSIEIKTSNVDLVTETDKKVEDLLKKGFLESFPDHCFIGEESPGCNLTDAPTWIIDPVDGTMNFLCIGAYPYNAVSIGFAVNKEIVLGVVYNAILDRMYTGIKGKGAYCNDKKLHVSGIQELSQALVLSEVGSDRSSKNLEQIFTNIKTIVDKAHGLRMMGSAALNMCAVAAGEADVYFEYTIHCWDMAAAKIIVEEAGGVCIDPEGGDLDLMSRRVLCGSSKELVETLTKELKHLQFPQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MND3</accession>
    <name>A0AAV4MND3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_68401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020000">
        <property type="protein sequence ID" value="GIX73873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MND3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7310" checksum="298139184E8F04B6" modified="2024-11-27" version="1">MCWTPLYEKRVDFETIVTECFAEGGSSFSVDSVCWSHLHEKAVVLENIVTECFAEGESSLSVGSEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSX3</accession>
    <name>A0AAV4MSX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_565551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002593">
        <property type="protein sequence ID" value="GIX75497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11022" checksum="067B4E384A949BE8" modified="2024-11-27" version="1">MKLKDPRLSSENEKPFLFRNNQSATPATSSSPFPKKMQISNQIRKRISAEKWRAFVRRINVTSMLRFMRVLFSGLFGTHGEAAVMSQGKNPRRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY72</accession>
    <name>A0AAV4MY72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_509921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020332">
        <property type="protein sequence ID" value="GIX77482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19845" checksum="E98BEBA21E65F08D" modified="2024-11-27" version="1">MLKPVLYLFLQDCQCTLMEYRENQNRNHQSVLQKGRFPMHPNGVQENQNRKRHSILQKGQQSSSTSTETFGLAFVFERPWFDVNLITKQKKKKKADWIVCHDVKTSPLSVHSGLPMKPLMEYIKNQNRKRQRFLQKGLKLMKTNVPMNPLVSYSSAFFVMVAENDNCPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8V9</accession>
    <name>A0AAV4N8V9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_766601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003098">
        <property type="protein sequence ID" value="GIX81118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8V9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12323" checksum="9B8B766F42CAAFDF" modified="2024-11-27" version="1">MSLLSERYYFVLLHTLFCKEFPNWKCFSLFNFPRAFPYHNAFIYISLNPLPFYDHFGLLRRIGSVRLFRRILLSMASPPSNISYQAGILFRFPVFDRVFVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ59</accession>
    <name>A0AAV4NQ59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Probable JmjC domain-containing histone demethylation protein 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">JMJD1C</name>
        <name evidence="5" type="ORF">CEXT_564301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021047">
        <property type="protein sequence ID" value="GIX85317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032454">
        <property type="term" value="F:histone H3K9 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045109">
        <property type="entry name" value="LSDs-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12549:SF38">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING HISTONE DEMETHYLASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12549">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX85317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="672" mass="76157" checksum="BD8A050D8904602D" modified="2024-11-27" version="1">MKPPEKPSVSQLKKTGEPFLQDGPCCEVAPRLPKCRECRMTAHQRSKKMPNIFCRFYAYRKLRYGKNGTISSAGFSEPSDALDEDLKLWLPPIDMRPQEKEIEISKFILTHIGDQFCDLVEMEREAQKLHVSTETTITWKRVVQGVREMCDVCEATLFNIHWVCHKCGFVVCIDCYKTRKNGLSKDESSYKDRDDYQWLLCTNKTPHEQEKLMLTQIIAGTALWDVGKALHEIRRKWNIPTYCNCGFYDNDQDSKSSSNGICKLMSAVTKCFSSDKDSSRESNGSSDYQRSNKRSVKSSVNGVIKQEDGLIGYISESGGSPLNWLADLALNSSTKTSDNQQDQDDEEKSSEDQESNADESAESDDEKNDNFSTLRELLIRPTGKMGSKSSGDSSSSQKTLTSTLDEVISCVIEQKVRKSDQKHNEKQLLHFTRRYQLTKSGRDLPPVRACMLTESSLLYPEIPHLWLGTGKILLLKDPYHSKNMQLFQEQWKRGQPVVVADVGKNLDPSLWCPESFLKEFGENKTDFLNCVCGTLIQSQPMKKFWEGFENLNSRIKDDDGQALVLKLLDWPPSEEFSDILPSRYDDLMKVLPLQQYTHREGVFNMASRLPECFVQPDLGPRMFNAYGISSSLGKGSTNLHLDVSDAVNVLAYVAASRDGKEEISSGSVYVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUF4</accession>
    <name>A0AAV4NUF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_523351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003675">
        <property type="protein sequence ID" value="GIX87363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10567" checksum="543859FCA4E59847" modified="2024-11-27" version="1">MVNPYAIILTIARRILAPNENGTDIANPSLKLEPTSFIKNNGNVSDDSLERSNLKQNGISRLTQLTDLDEIQKNAPGLPRLQSSHREADWSSLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWL6</accession>
    <name>A0AAV4NWL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_125571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003791">
        <property type="protein sequence ID" value="GIX88680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11721" checksum="A4C8EF3C304A8502" modified="2024-11-27" version="1">MEKNKITVLRIFSRTQSSASVWAEQHNRYRESPDKEVEISKQKALKRTPLESKSKQTQINFCLPLSSRLPASLLLPQIHARCLMRTRGLRTNLQANPYVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXW7</accession>
    <name>A0AAV4NXW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_280041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021409">
        <property type="protein sequence ID" value="GIX89254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17899" checksum="35FC6F846FBD4175" modified="2024-11-27" version="1">MKELVEEIYISLRHGRFKKRGFWESVCSNFKRLNLLRRWLSAREVFNGVYKQHQQQQNIHKNLNHQQHCSGRNIELTSQLALDQRGWFQRPKFQERERKRGADFHLLIIILIRDGEVPSKSDGNTCRQADSNRRVVIHKEDFKKGACSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4R3</accession>
    <name>A0AAV4P4R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_410641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021478">
        <property type="protein sequence ID" value="GIX90147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10915" checksum="688A44E7E5675263" modified="2024-11-27" version="1">MASSPVIKNNTQVFFLAATNSKTNLTTNSIVIQSSFPTPLGYVFDDFARDHNSWCYALEELHEPHTSCLNRLKKRPVKEFARKLIHCREALRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDZ2</accession>
    <name>A0AAV4PDZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_805891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004399">
        <property type="protein sequence ID" value="GIX94628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10355" checksum="645B5BA46E358E6C" modified="2024-11-27" version="1">MTTLANRIKPSSGIKRRADLPFPVSPGEGERWADDLRWERWARGGLLQHLCQGSTGARRPQRRPHQHKIAAPPSLQLRRHSPLHVGTSALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PH11</accession>
    <name>A0AAV4PH11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_559901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004520">
        <property type="protein sequence ID" value="GIX95451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PH11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24943" checksum="A41B65C0D8CEB89B" modified="2024-11-27" version="1">MNVGFAADLLYGKWPKVRMLDNKKNTLSRFVPRRKNGKKEEKRKERQNYFPPPWKTNIRERMKSTQTAREREKQHKNRDLCSQNSSVLKGKGLKWKCPGLMTSNPQFKIQCLVREMFYKNVFAHLMSRLLLLQSITLPSFAKEEPAASASNVNATFDNKFLGEFESLSFFFSSKFLRSRSIRVANLPEDRATRSTNQDSTEVQSCLSHNPLDATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PML0</accession>
    <name>A0AAV4PML0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_487931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004775">
        <property type="protein sequence ID" value="GIX97401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PML0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX97401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16498" checksum="71AAAA0EDDD5358A" modified="2024-11-27" version="1">MTVHVDSASSDSDDGNYIISVKGAPDIILPFCSTILLEGEVKPINDYHLECFRRDVQDFLLKGHTVIGYCDMEMPKSNFPSNFEFREDSIPLKGLRFLGMISIHDPVRPSSVEAVRNFRNAGIKVSEAEFLNLTVVIMSGTSVIDDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPG3</accession>
    <name>A0AAV4PPG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_803591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004930">
        <property type="protein sequence ID" value="GIX98569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13421" checksum="1038499621F2D9DD" modified="2024-11-27" version="1">MDNADFTLGSRLTPCPRCYGSDDATTSWTHVEARPGVHSKEKRNGQFGRGWKEDPIESLLSHSSLPPPKTRGKRPVQQGIDLVTKFFCCDLKDVNADYHRSIFKDFWITGVDIPTFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRY0</accession>
    <name>A0AAV4PRY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_490301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004982">
        <property type="protein sequence ID" value="GIX98916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14774" checksum="8209584659AD30B5" modified="2024-11-27" version="1">MPADFEERSHRPREKRILERSQAHEQLQARPHSAAAWGVPGKQPLLHPPGADGRRGPPLLPAQQQAHPDAELQSGDGRPDRNLHRCCQGLQVFGRHAFRPQGPRGAQLPGVEHGPGAEDREDRGLRAGQGRVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1F0</accession>
    <name>A0AAV4Q1F0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynein heavy chain 8, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dnah8</name>
        <name evidence="4" type="ORF">CEXT_143121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005419">
        <property type="protein sequence ID" value="GIY02187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1F0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="3">
        <location>
            <begin position="24"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="97"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY02187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21644" checksum="EAA1681DF96F5DD2" modified="2024-11-27" version="1">MVALPIQFRRLFNDIVYNFVNMFMSTTGFLAALQNFPKDTINDEVVELLEPYLIMKDYNMETAKRVCGDVAGLLSWTKSMAFFFGINKEVLPLKYNLAVQEARLAVAMKELKSVEQELQDKENDLKSVKAQYESAIANKEKLAEEAAVCRRKMSRASMLITELAGEYKRWTDESKQQRTDQKVMWME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q684</accession>
    <name>A0AAV4Q684_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MAGUK p55 subfamily member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MPP5</name>
        <name evidence="9" type="ORF">CEXT_400301</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAGUK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005763">
        <property type="protein sequence ID" value="GIY04864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q684"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030054">
        <property type="term" value="C:cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06798">
        <property type="entry name" value="PDZ_MPP5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12036">
        <property type="entry name" value="SH3_MPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000088">
        <property type="entry name" value="MAGUK p55 subfamily member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000469">
        <property type="entry name" value="MAGUK p55 subfamily member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004172">
        <property type="entry name" value="L27_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036892">
        <property type="entry name" value="L27_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050716">
        <property type="entry name" value="MAGUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035601">
        <property type="entry name" value="MPP5_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23122">
        <property type="entry name" value="MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00569">
        <property type="entry name" value="L27"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101288">
        <property type="entry name" value="L27 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="PDZ" evidence="8">
        <location>
            <begin position="257"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="346"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate kinase-like" evidence="7">
        <location>
            <begin position="474"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY04864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="673" mass="76795" checksum="3D28E9363F98C3A6" modified="2024-11-27" version="1">MCKLDCSSNKHLSTQEVLSHHDKSQLKSREAHFSPRPKTKMKLQEELRKRKEDEERHAQEEEFLRSSLRGSQKLRALEKRASSGLENSAFLLEEGDAPAAPPPDGKLVASEPDGEPPELTKLYEPATLLDTLHNLEAGLAKLGLSESMVELEKLFHNPEFQSLLTLHNKVQDLSCFKCLPTPVCADAQVISLEVVRALQDVPSKDAKELLHLLGKHPFENLMFCHDKVAASQVVPDISEEEELLARLSQYTEESIKIVRIEKTTEPLGATVKNDGEAVIVGRIVKGGIAEKSGLLHEGDEILEVNGLELRGKTVNDVCDIMASMSGTLTFLIVPTQYDIPKQQTRESVIHLKAHFDYEPDDDLYVPCRELGMSFQKGDVLHVISQEDPNWWQAYREGEEDQLLAGLIPSKNFQQQREVMKQAVVGDTREKKSKKRHHRRKKKKMYNLSYNDDTDAEQILTYEEVRLYYPRAHQKRPLVLIGPQKVGRHELRQRLMEDTNRFAAAVPHTSRTKKDSEVNGVDYFFISRTQFEADILAGRFVEHGEYQKSYYGTSLDAIRSVIDAGKTCILNLHPQSLKILKKSDLMPYVVFIAPPSLEKLRVNCLKMDQPVKDDELKDIIEKGREMEEFYGHYFDLVLINVDLEKTYSELLHEISVIEREPQWVPATWIKDDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6H0</accession>
    <name>A0AAV4Q6H0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Insulin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_727441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the insulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005596">
        <property type="protein sequence ID" value="GIY03560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6H0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.100.10">
        <property type="entry name" value="Insulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016179">
        <property type="entry name" value="Insulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036438">
        <property type="entry name" value="Insulin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022353">
        <property type="entry name" value="Insulin_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00049">
        <property type="entry name" value="Insulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56994">
        <property type="entry name" value="Insulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00262">
        <property type="entry name" value="INSULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043394247" description="Insulin-like domain-containing protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Insulin-like" evidence="5">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY03560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8331" checksum="1186D4709BC76A42" modified="2024-11-27" version="1">MLRNLVLCSQASILVFVMLCMVTAEQHGNSVSYYIEINNSSIIHGPIREKRGVVDDCCRQSCSFTVLRSYCGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBW1</accession>
    <name>A0AAV4QBW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006122">
        <property type="protein sequence ID" value="GIY07538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8801" checksum="34FFA1CB6B90E8F7" modified="2024-11-27" version="1">MEGLLATLVAVGTVAGHFLKCVAPHFEEDRGVLKGTSLKNSFSIVSYLLQWSLDLGLYFISSLFAGGRRVLISCLVHGDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIX3</accession>
    <name>A0AAV4QIX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibroblast growth factor 8b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fgf8b</name>
        <name evidence="2" type="ORF">CEXT_17861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006372">
        <property type="protein sequence ID" value="GIY09390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20836" checksum="362C366B77280555" modified="2024-11-27" version="1">MASCKSFSVDLEKGAPSIRENPTRSWKSHDIRRSYKLYNQCSGNHVQVVGKLVNAKGSADNPFVNMSFISARSRHHQNAINIVGQKTKNYVLQQKGQTYSQEKWQEEIVSVPRRSQQRPLHSATVVVRSYMVRWFQQESMDEYIPPVKIKPWRLKELLTEGHGHHRSRQQRKVPKTPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJG1</accession>
    <name>A0AAV4QJG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Niemann-Pick type C1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_16961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006383">
        <property type="protein sequence ID" value="GIY09454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070062">
        <property type="term" value="C:extracellular exosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040250">
        <property type="entry name" value="Nucleobindin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19237">
        <property type="entry name" value="NUCLEOBINDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19237:SF20">
        <property type="entry name" value="NUCLEOBINDIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="10"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY09454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="34901" checksum="51B1939C42940D59" modified="2024-11-27" version="1">MEEEFHRMREHIFNETDVNKDSLISLEEFLKMTQQQEFERDEGWKGLDEQQVYSDAELQEYMRQRQMQYQHGQYYGDQRMYYDVEGQQHGLPPQINYQGMPQYPGQGHPQQFQQGHPQQFQQGHPQQFQQGHPQQMPQGHPQQMQQGHPQQMQQGHPQQMQQGHPQQMQQGHPQQMQQGHPQQMQQGHPQQMQQGHPQQMQQGHPQQMQQGHPQQIPQGHPQQFPQGHPQQFPQGHQQFQQGQPEQVPVAHPPQRVQGQPLQPLEQRAPNFKNEVPQVDKKPIESQNPAAQQGSAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QK04</accession>
    <name>A0AAV4QK04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arrestin_C domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_4781_1</name>
        <name evidence="2" type="ORF">CEXT_699191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006456">
        <property type="protein sequence ID" value="GIY10018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QK04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF144">
        <property type="entry name" value="ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="22453" checksum="5EEC9D8BCEA9E50B" modified="2024-11-27" version="1">MGADQRATCCLCCRRGVVSVRSNLERSAYCCGESIRLKADIDNQSDEVLRIKLKLVQYVEFFIDRGVLGMTKEVNHTVLEYRGDPINPNTRSKFDSSSSLVVPVMPPTLIGVCRLLQIYYVLKVWVEMEKSGDDLHMNFPITIATCPFRIPNSNQQPKIEYEMCCDHVEGGMYIGPEFLLARYTMAQWDAWRKARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUM4</accession>
    <name>A0AAV4QUM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_338971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006898">
        <property type="protein sequence ID" value="GIY13170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043461593" evidence="1">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9515" checksum="66199F165C45AE2C" modified="2024-11-27" version="1">MNWKCVLYFLVIEIVCLAAAEPLFNGTTANDTEVVEFRMFTDRLRNLMSRLYERSDRYDLASYLIRAVFEHFFALFYNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVU4</accession>
    <name>A0AAV4QVU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_768221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006707">
        <property type="protein sequence ID" value="GIY11838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15747" checksum="3DA809AFB8495854" modified="2024-11-27" version="1">MFRGKAASRFETFNMNVRHHTREPVFIFRKDRTPFEACPKTDTRQSENLRFCCFLSHLTHREQKNQHVYFEQSKTDRENEITRNHVLKLGELHSNPLFGDGLFSSEEWQHANRQTIRARAIDFKGHKREEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1A8</accession>
    <name>A0AAV4R1A8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aryl hydrocarbon receptor repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AHRR</name>
        <name evidence="8" type="ORF">CEXT_739301</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007243">
        <property type="protein sequence ID" value="GIY15510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1A8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034751">
        <property type="term" value="C:aryl hydrocarbon receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004879">
        <property type="term" value="F:nuclear receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19730">
        <property type="entry name" value="bHLH-PAS_spineless_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000041">
        <property type="entry name" value="aryl hydrocarbon receptor repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039091">
        <property type="entry name" value="AHR/AHRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10649">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10649:SF12">
        <property type="entry name" value="SPINELESS, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="137"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY15510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="24006" checksum="4CD4094E35CE9EF0" modified="2024-11-27" version="1">MVKGGELIRGSLDREKWKGGPGGTGGILEVIDRPVVVLKLKDRTPGHFDKGTHSRNRILLLLAQWLTLADNAEATMEGLSPMGDRDTGDWSPARLTQRPPLPSPLYHWGCTHADDPISLKAPIPALAVPTGVRVPPKEGQTKSNPSKRHRERLNAELDTLASLPPFDQNVLSKLDKLSILRLSVSYLRTKSYFQGKGASLLFRNIKVHQQRLVQKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAF4</accession>
    <name>A0AAV4RAF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_592951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007696">
        <property type="protein sequence ID" value="GIY18943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13970" checksum="2BC0932C19C39DCC" modified="2024-11-27" version="1">MVQEPLLIQKASKLRSRSSEFVTMVLPFLSIKLSVTAEARVNFVTKKERKLAGIRKSCIWQSDLSIFIVDHVATEKASDEDSMIVSCNLMSLLMMIRCLLDTKDPHCIFEKDRCTMPKEFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDV8</accession>
    <name>A0AAV4RDV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_550591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007721">
        <property type="protein sequence ID" value="GIY19141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14843" checksum="291023DED9A73FA6" modified="2024-11-27" version="1">MKSHQLSLRGRQFGGTRGENELGLWSFIRLECGDETKENDLPQVKRQNEFCPAICGRRQLDVELLLPRVPGQRGGPHTLVAKMKYFNIDKRHARRLSDRPIRFSPLSRLLLSSWELPSSDSSQQTDLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RG87</accession>
    <name>A0AAV4RG87_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methionine synthase reductase</fullName>
            <ecNumber evidence="11">1.16.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Mtrr</name>
        <name evidence="15" type="ORF">CEXT_561751</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.8" evidence="11"/>
    <dbReference type="EMBL" id="BPLR01007827">
        <property type="protein sequence ID" value="GIY20024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RG87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000059">
        <property type="entry name" value="5-methyltetrahydrofolate-homocysteine methyltransferase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000007">
        <property type="entry name" value="Methionine synthase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="13">
        <location>
            <begin position="12"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="254"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY20024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="658" mass="74790" checksum="7B028CA0DBB03882" modified="2024-11-27" version="1">MTAFQPQDLKRFILLYASQTGQAQAIAEEISETAPFYGLIADIYCLSLTDRKFCIEKETCAVFIVSTTGDGEPPDTAVKFYRRTNGLLLNKNYLKKLNYTLLALGDSNYDKFCLFGRNLNKHLECLSAKLFYEVGYGDDAYGIGTCVDPWIKNLWPALQKLLGVEPSTTNGFVVNFFDENYLLKYLNMTSIESLSDEEIKTLTLKDIPHLIKYSHIDKLGLPSLPSPKLAIAFEETVKKACYMPNKNFTHPQASDIFKVRLTDAKKLTSEDTVKNTFELTFELEIENNKFSPGDAFGFICPNPPDEVETLLERLNIIQYAETPVKLHTLETSAKRKLFTYIPQYLSLRDIFLHCIEIRSVPKKILSEYTSDLHEKHALLFLSNPIGAKFYTSCIRDPSISILDILMTYQSCNPPVEKLLEHLPCLKPRFYSVASSPLQDNKSFKIVFNVLKISNERGRYKDREGVCTDGMSNLSLGCNEFSIFTYMGVNIYFYPPDNLKFPIIMVGPGTGVAPFIGFLQHREKQLETVHNNCGESWLFYGCRYKDKDFLYRSELYRLQSAGILSHLKISHSREEPLPSNITSRYVHESIKQNSDAIAAAVCGAGGRIFICGDGKHMAKDVEQAFTEVFQLYNNFSASEAKEYVHTLKAEKRYVCDVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHL9</accession>
    <name>A0AAV4RHL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_716771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008017">
        <property type="protein sequence ID" value="GIY21418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="6957" checksum="6E931D72A465574D" modified="2024-11-27" version="1">MELLLDIPTDYKIDVGSLGKVEVGSLSKVDDGSLGKVDVCSISVNPGGLGEVDYLQMNNTLNCLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJD0</accession>
    <name>A0AAV4RJD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_337161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007856">
        <property type="protein sequence ID" value="GIY20232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="18670" checksum="34B9C2BF391C902F" modified="2024-11-27" version="1">MNLENVTNHIVKLTYNERYESHNDIRERHELHSKLTYSECYEPYNELRERYESHCKLAYNERYESHNDIRERHELHSKLTYSECYEPYNELRERYESHCKLTYNERYESHNDIRERHELHSKLTYSECYEPYNELRERYEPHSKLIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJE4</accession>
    <name>A0AAV4RJE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_726501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007959">
        <property type="protein sequence ID" value="GIY21031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18204" checksum="04606F9159C2CF49" modified="2024-11-27" version="1">MKYKKWNIPTENILVKLRIKILVALISLKNANIAAVTPSTIVKACYICSDNVYLLESHLSKRNMEHMKDSKGSNMKKRMKLEGMEDQDFAEVGITDNEPILIDSETVVANVHVHFVPNIKKKSCKKKIKNTTVATLTHQTADNFMGRLCFFMLVSSQLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RN23</accession>
    <name>A0AAV4RN23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_121391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008049">
        <property type="protein sequence ID" value="GIY21680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RN23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8990" checksum="32CD7ED13DEF5E12" modified="2024-11-27" version="1">MRADFRRFICGHRLVWEQRTVFTPLSRFIPTVRYSIASMWKRVKLLRSIIREISLEELVVYLDKISSAPHINLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPP6</accession>
    <name>A0AAV4RPP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_106818_1</name>
        <name evidence="1" type="ORF">CEXT_641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008369">
        <property type="protein sequence ID" value="GIY24233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22955:SF65">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22955">
        <property type="entry name" value="RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="27733" checksum="EFCDB6E81C58394C" modified="2024-11-27" version="1">MADAKNGTAYVDFWSRARTIFLQNVEPISPVLGLQWDRIEDSLFIPFKSEPIADLSKRKLLSIVHSVFDPLVSAKLILQEAWATEANWDSPLPDELQSRFSTWYHGLSYISQLKFERCIGYGKRDSLSLHIFCYASKNAYATVIFLRSESSRLAKYVVTVLSLKEVPTYYWADATVALCWIQREENWGVLVNNRVKEIRSLSKKEYWRHIPGKLNTADIASRGCTLQHLSQYGWWEGPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUP6</accession>
    <name>A0AAV4RUP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_695301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008365">
        <property type="protein sequence ID" value="GIY24182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="17437" checksum="2CF5BFA3F2018BB7" modified="2024-11-27" version="1">MDKEEACSGARKLITKYRKLLTWWAFVREVPRLMNSNIDVIFELLTYFDMPFHILMKHVATMKELLQKCIVHCVIIKEHLEELCRNIDRVMNTVVTYNSESGIYFRNQYENAMKDAWIIFVMLCDCKKEFLLFCETQYKIFETLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S253</accession>
    <name>A0AAV4S253_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_723081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008841">
        <property type="protein sequence ID" value="GIY27682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S253"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044011248" evidence="2">
        <location>
            <begin position="21"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY27682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="500" mass="42988" checksum="B0B42FF732FD68C8" modified="2024-11-27" version="1">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</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7E4</accession>
    <name>A0AAV4S7E4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_762571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008975">
        <property type="protein sequence ID" value="GIY28667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7E4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8745" checksum="63F01A785CBE3238" modified="2024-11-27" version="1">MCTLCMKPVDYGDSTDMSEEKDSSEEDEAERIETDKKDYKYQYGKREATSEGEDQGSKTPGKKRQLATVHDLSDDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SCU0</accession>
    <name>A0AAV4SCU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_440011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009231">
        <property type="protein sequence ID" value="GIY30476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SCU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13217" checksum="E642212B5044C6C3" modified="2024-11-27" version="1">MEENGIHCLHNFEQLPFIKIFLCTESKEKSAFISVSTTKMTFKVLSEMNLSRMVRVSCKGAGRPTARPESKIAGYPSSPLRKQVMMRHTCVLGRVLWLLERKCHASDVSSRIFRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHM7</accession>
    <name>A0AAV4SHM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_303891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009531">
        <property type="protein sequence ID" value="GIY32676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12480" checksum="4287AC124F3D9EA5" modified="2024-11-27" version="1">MQAFWPLGIPLFGKKKEDRNGKEKKAVDSIPELLEVVKIRSPLSRLASTSVRLCRTAHFMLTSKSRTELIVAVELTEKEREKRHRSMVGQSNSYVFACNISNVEQNILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJ82</accession>
    <name>A0AAV4SJ82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_241043_1</name>
        <name evidence="2" type="ORF">CEXT_774971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009694">
        <property type="protein sequence ID" value="GIY33850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJ82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14556" checksum="C2E9D2B71FFC17AD" modified="2024-11-27" version="1">MLRLAAGDNGEGDAERNNRLPWQTKWNSKCYTIINTTLSTQPYSDGNYSPSSSPVSITSSTTPVPSPGHSDNANAIRTFYDLTNCSPMKMVNSNTAFVFPENNLLYKGNTSVHNVTRPARHYSPIALRQSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLX8</accession>
    <name>A0AAV4SLX8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_303441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009532">
        <property type="protein sequence ID" value="GIY32688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043405549" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10675" checksum="F54C9DC7DEEEC80D" modified="2024-11-27" version="1">MTSAFCMLLRACFACLSHLIIGPGAQRTFLSFLIGFPEWEVIVEDKRKTNSFGPIIMQTAALSREGRNWFLSVQSNGDKSSKEAFQAPRFEMYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SN09</accession>
    <name>A0AAV4SN09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_231961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009903">
        <property type="protein sequence ID" value="GIY35374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SN09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10934" checksum="363AC1EEB0885BFF" modified="2024-11-27" version="1">MVKKKSALSQLMVDCVLKAIFRLSIMDRTLKAKSFYNAATAVKVCCHTNRQWNISLLVHQIQNGGTPFSKDYDTFINLCGRHFSLPLSKAFNKMHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSQ2</accession>
    <name>A0AAV4SSQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_464371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010000">
        <property type="protein sequence ID" value="GIY36024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8612" checksum="4AB6B93EDFB6D99D" modified="2024-11-27" version="1">MPMKKIESKTWNKFLKIRFDELNEDYDAEANENANQEAALCSFVIRSGGCSRGLSPNQHIQQKVEIVLIALAACHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2D3</accession>
    <name>A0AAV4T2D3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010487">
        <property type="protein sequence ID" value="GIY39606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2D3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="17318" checksum="A2C93B194BEE8002" modified="2024-11-27" version="1">MRYHPRERHFELFQHKLFPLEDSPASNSFNKSPGRQHERHLAPFGNFVVPFVEARARTKIYGFLTRPHLSITTGAPSLCAPLFKEPLSVSDQEIVEIQEGHRTKPGPLSYSNLSRENCYLWRKRHSDIVKQSLRYRSRIGKSFSAQIPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3Z7</accession>
    <name>A0AAV4T3Z7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_472621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010465">
        <property type="protein sequence ID" value="GIY39455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3Z7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11517" checksum="B19F4149E207908B" modified="2024-11-27" version="1">MVSFQCPISGQDHTFFLSLPRSAHWLSLDTFVRDHCCPSGISSPQDSFPGEKWSMMSPASGFVDHDSLLSEILDQCRVDYLYSMCSSSLHLTSLRNMGPLNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDT3</accession>
    <name>A0AAV4TDT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_395521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010919">
        <property type="protein sequence ID" value="GIY43017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10125" checksum="8633EE77D08E9BB7" modified="2024-11-27" version="1">MLREYRRCMENRSQVREELIEKTFENLRSIPEPECYECKFGVPKRRTDDIHLTLPQIFDAKSRDRSTLCILNQPQGHSSAKSQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TET4</accession>
    <name>A0AAV4TET4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_296321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011053">
        <property type="protein sequence ID" value="GIY43897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TET4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="8122" checksum="2D533CF19F2BA863" modified="2024-11-27" version="1">MLKESQKYEASEADRGPTVYAVKPSLKEHWTDEIEESWLQLFRYISYIMKRAMMETYTSQEIPVDNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFA7</accession>
    <name>A0AAV4TFA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Potassium voltage-gated channel subfamily H member 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">KCNH8</name>
        <name evidence="15" type="ORF">CEXT_803621</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>K(+)(in) = K(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29463"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011050">
        <property type="protein sequence ID" value="GIY43891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.260:FF:000002">
        <property type="entry name" value="Potassium voltage-gated channel subfamily H member 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003967">
        <property type="entry name" value="K_chnl_volt-dep_ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050818">
        <property type="entry name" value="KCNH_animal-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217:SF637">
        <property type="entry name" value="EAG-LIKE K[+] CHANNEL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217">
        <property type="entry name" value="VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01470">
        <property type="entry name" value="ERGCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="14">
        <location>
            <begin position="84"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY43891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18486" checksum="762407A8C7DAE48F" modified="2024-11-27" version="1">MSLQSSKRMYARRSQYHTKLRDLKDFFRLHQIPKELKQRMTDYFQTIWSLNHGIDPNEILREFPDELRGDASMHLHKEILSLPIFENAPQGCLKLLSRHVRSNFCAPGEYLVHTGDALTNIHFVCNGSMEVLQNGMVVAILGMPFNYQIGILKPELQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGV5</accession>
    <name>A0AAV4TGV5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c biogenesis B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_637101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010947">
        <property type="protein sequence ID" value="GIY43218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24772" checksum="0156D380A2219832" modified="2024-11-27" version="1">MRVLPLRTGFWKTSESLSLRVSPPDREKQTTPSLAAGDTPRSIGLQWTRENSLASSPSVGVAVWIHKNLRPLFTEEKWPLCFSHPITMSPLMDGRSWLFLHVLTRLYAQLFYEFLHGSQLYGHPNEHRAPSIGEIRGRGGNSLSKQVDGSHLKNLISRSIQMGEISQMKEMTVECFIKKSAASISGEIGWRIYFCGRGSSCLQIDSGHGALPQESVFPCRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQY3</accession>
    <name>A0AAV4TQY3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_727651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011611">
        <property type="protein sequence ID" value="GIY47722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000159">
        <property type="entry name" value="Speckle-type POZ protein B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="40"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="21298" checksum="A5A18E9BC4E23341" modified="2024-11-27" version="1">MVFTRTENNEEVSSGLREELHDYQNILGDLSTLYDLQILCDVHLKTRTESFPTHKAILCARSYVFRAMFTSDMREKNSDCIKVEDLDDDIVHRFLAFLYTDSVKDLQWETAIKLYYAGDKYEIELLKAECSSFLKDNTSSFNVMELLLLADRHQDLGLKTFAEEYILRMDDYIFGSDQWGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVJ0</accession>
    <name>A0AAV4TVJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_492251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011688">
        <property type="protein sequence ID" value="GIY48228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12431" checksum="585D8A6D6A7BD451" modified="2024-11-27" version="1">MTLIGKISTCFENMCYDHGTLVLRARLKTEKVLPKDVRSIHFAATNCLCTFTQKPKTPPKLHLLSLRLFAFSREKRLSLRISGGRVSKDGEDEFSGNRPVIFLFLLNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYY7</accession>
    <name>A0AAV4TYY7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ensconsin-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_84088_1</name>
        <name evidence="8" type="ORF">CEXT_795721</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011996">
        <property type="protein sequence ID" value="GIY50589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051483">
        <property type="entry name" value="MAP7_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008604">
        <property type="entry name" value="MAP7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073:SF1">
        <property type="entry name" value="RETICULOCYTE-BINDING PROTEIN HOMOLOG 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05672">
        <property type="entry name" value="MAP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="324"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="391"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="620"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="817"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1014"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="72"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="588"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="710"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="817"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="891"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="912"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY50589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1123" mass="126204" checksum="B66E7C6D012E433F" modified="2024-11-27" version="1">MSEETTPSPLSKAHTKESYWFAHSRNGDASPGAALNDFKAGGDAKELQVQKDKEEKIRIFREQQEEERLKRMRDLEQQFMQSKKHRELQEEERRRRIEEARVKELERRQQVEERKRQIWEAEQERKEAILRRNMEREARIEARRNAQRNSACFAFGSSTPRTFDLDLAAIGMGRSMNAGSVLMSSVSRRSEERELGPPPRATSACSLDRKFGEDCMSRSMVSLSSSTFRGRKRTDIMPTLTRERSITPHITPRGNGCMRAVSMTRLDQLAQPRRTYRDPRSYAADTTTNEGPRTVSPSMSKSMCNLANSSTVGRKARTPISYKGSMTRSMLHLPDPNPKERRELTPSPTFPKSGMRSAQSMMHLAAAPRLTRAARLRAEALAGNRTVSAWNLNKPDSYQSSHYLSPGKDSSRSPSRPQSSMSGTSEISTASSSAVNMRHRPGPRRPRPYSVHGSMVDGSSVSSQIVKKEPERPVRLHERNISASLQKPPRAKSANRENPEIKNSKQVTAPKKPVPPPKPVDVAAKAKPHPVPIKDNLRKRGKPSSRPLSDDSQASTNVNESSAKNIHSLEKKESSELKGPLPTSDIKPSSTVTSPTTDSEMLISSDDSKVSALAGSDVDTFSQSVTDSDCKAEESSVATPSKSQSISLVDTAGAEETVQKDDSVAQIIPTKAQQPEPKTEIPYEAQQKETKPEFPSENLQKNVKSEVSLEPQQNEMKTDIQSQMQTSFTDSLPKEGMPSKPRITSEEEARAALAEKRRLAREQAEREAELERQRLEEIRRQEEEKKRLEEEEQRRFEEEQIRLAALHRQLEQEKLAKAIEEQQQREREELERKEEEARQRAEKEEQDRKAREEAEKQRLELEEKLRKEEAERAERKRRVEQIMARTRGKTASAPAQSPSNPPSDNAFKPVQSVETPAVNASNSADVSRVNIITNGIKDMSVETKNTSINGTTEKHMSNSSSWSKQMNPLPDILNSENIANHSAKSNGPFMVSDEQSSKISVSNSFSILSNRTLSANDDMSPQTNGYSSHEEMSCTTSPEENADVELLIDIQSSQQQNYKSDPTDFTKLVDLEPTSLDNNVNNENYLINVDDVNSNLFNSGNPFNGFEDSLQKKQDTPVTDLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U232</accession>
    <name>A0AAV4U232_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_93481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012166">
        <property type="protein sequence ID" value="GIY51820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U232"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10442" checksum="B2E2D3C6B02FA612" modified="2024-11-27" version="1">MMTRKINNNFVERNEQKFEHTTEQREVDELITDITFTNVSQANGHSIPAASVQNSSSPDPLIVCIVQIITDEYRTDGGYNRIQNRWRLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U542</accession>
    <name>A0AAV4U542_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_233881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012300">
        <property type="protein sequence ID" value="GIY52850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U542"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13555" checksum="5F4D88C67D562B04" modified="2024-11-27" version="1">MINNINVVADRNSRRLKGPIFVHEPLETVEFSNSTGAVISCSAQVIGTRNPLGEEGRNPVSTIPGIRQVRPDNSLVFFPINTDQYRQDVHAAVYRCIATNKVGTIRSRDVVIKTGRLRINII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U662</accession>
    <name>A0AAV4U662_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012336">
        <property type="protein sequence ID" value="GIY53232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U662"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="20272" checksum="CA3F1E31A64EA477" modified="2024-11-27" version="1">MRNVARDNSLCLIINPGSGSVDIITSSSSAISARWAIDTGFKSNPDGVMDVCAQFEESPNVAASSIESSRQLCTVREMSAPAPEAAAKDQDAFTERKTPNWISKSVCVLFPFLSNFTFGFKCAQFAESPNVSASLIELSRQWCTVREMGAPAPEAEEKDQDAFTERKTPNWISERVCILFVLLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHP7</accession>
    <name>A0AAV4UHP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ninjurin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Ninj2_1</name>
        <name evidence="8" type="ORF">CEXT_274832</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ninjurin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012871">
        <property type="protein sequence ID" value="GIY57239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042246">
        <property type="term" value="P:tissue regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007007">
        <property type="entry name" value="Ninjurin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12316:SF17">
        <property type="entry name" value="NINJURIN C, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12316">
        <property type="entry name" value="NINJURIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04923">
        <property type="entry name" value="Ninjurin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY57239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="13266" checksum="5ED37B2468989F1F" modified="2024-11-27" version="1">MATVSPTNAANGGGENAGKTSQNLDANVYATKKTIAQGLLDVALLTANASQLKYLLQLVLTGCMMLLIANTNLNEIKKQRRADNLNNAITIGIFLVAILNILIAALGIKNSDDLQAAVLSTLGTSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UM58</accession>
    <name>A0AAV4UM58_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial</fullName>
            <ecNumber evidence="12">6.2.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GTP-specific succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="12">G-SCS</shortName>
            <shortName evidence="12">GTPSCS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Succinyl-CoA synthetase beta-G chain</fullName>
            <shortName evidence="12">SCS-betaG</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SUCLG2</name>
        <name evidence="16" type="ORF">CEXT_489201</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10 12">GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>GTP + succinate + CoA = succinyl-CoA + GDP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22120"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.2.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.4" evidence="12"/>
    <dbReference type="EMBL" id="BPLR01013123">
        <property type="protein sequence ID" value="GIY58888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UM58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000004">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03221">
        <property type="entry name" value="Succ_CoA_betaG_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034722">
        <property type="entry name" value="Succ_CoA_betaG_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF10">
        <property type="entry name" value="SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 12 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp fold succinyl-CoA synthetase-type" evidence="15">
        <location>
            <begin position="33"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase/succinyl-CoA ligase C-terminal" evidence="14">
        <location>
            <begin position="300"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="359"/>
            <end position="361"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="12">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="12">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00053833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY58888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="424" mass="46568" checksum="5758AFADE38D47B5" modified="2024-11-27" version="1">MALFHRIAKNTSYLCNIIERKLPVSVVPVRHLNLQEYQSKQLMQENGINVQNFRIASSINEAEEVSHSFHVDEYVIKAQILAGGRGKGLFSSGLKGGVKLTKNPKDVPKFAEQMLGYNLITKQTPKNGVTVNKIMIGEAVDIARETYLAILMDRESSGPVIVASPAGGVDIEEVAKQTPELIYKEVIDINRGITDSQARSIAQKLKFEGDLLHQAAQQIKKLYELFIKVDATQIEINPFGETKDKRVLCFDAKFNFDDNAEFRQKKIFDMDDHSESDPREVDAAKFHLNYIGMDGNIACMVNGAGLAMATMDIIHIYGGSPANFLDVGGMVQEEQVYQAFRILTSDDKVKAVLVNIFGGIVNCAIIAKGITNACRNIQLKVPLVVRLEGTNVDEAKAILANSGLPIVTASDLDDAAKKAVASLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPN1</accession>
    <name>A0AAV4UPN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_68391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013235">
        <property type="protein sequence ID" value="GIY59718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11556" checksum="9D900615088EE8AC" modified="2024-11-27" version="1">MVLFHEKCYNNIQASEIPLKVSTYKKKTATLITPMTTYQRRIFQDFIMAEISSHYETAELSMWKAEISHPPNDKKRFTGLSSIRKVVELNFEFNYNLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQR0</accession>
    <name>A0AAV4UQR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_79521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013275">
        <property type="protein sequence ID" value="GIY60078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10621" checksum="DEAA08DC9B17F0D9" modified="2024-11-27" version="1">MQLSINANIKKPSIPFLRCQSFDRHLFDHHKGSGQTGIRKNSGHSRFDKRSPLLSEHVTMTVNVYRMGRRRATGLPELTGFQCWMYITEGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUL9</accession>
    <name>A0AAV4UUL9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5'-nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_699171</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01013512">
        <property type="protein sequence ID" value="GIY61762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006196">
        <property type="term" value="P:AMP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF24">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="5">
        <location>
            <begin position="164"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY61762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="271" mass="31250" checksum="5ECB891A3E642F11" modified="2024-11-27" version="1">MALKPFLPYFLPSIDPVILEILELYRLRTLSLYFLPNRSRYRRNLGALSLYFCFPIDPEILELYDLRTLSLCSLPNRSRDLRNSRPNAILFLFPNKDSRDRNSLNLWPGRETQGEAESGSNERFPEGRSSDVPHEGMQPGQLPGRRRSQLLHRAAHGDRMEFRNVTFEDIISVAPFGNTMDVVALKGKYLRQVLENSVSDYDLDSDHPRVCSFSTYNVSMPVGSRLIEAHVRCADCRVPHYQPLDEEQVYWVVMSTYMAKGGDNFVNIQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UW35</accession>
    <name>A0AAV4UW35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_602371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013579">
        <property type="protein sequence ID" value="GIY62111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UW35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21747" checksum="6D75D0DA700163EE" modified="2024-11-27" version="1">MIDLRVFWEYFQVGNQQIIRKRQKTYWRKKLMKMREIIRDTKKGARNLKEIGGSKVKSVRLDKAVKSIKTHILVLEGREGMLDHPLSLFRCKGPVNVKYLKANMQNDIPQIATNVQFWWQNLTAIAYTSSIDDGSGDFVGQRENQQNTDICEFIKNIYEFYIVDGDPDRTQWPPKWGMTQPGGYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0S1</accession>
    <name>A0AAV4V0S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_685041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013780">
        <property type="protein sequence ID" value="GIY63731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10747" checksum="53FBDD9E41665E71" modified="2024-11-27" version="1">MRCFAFHNNLLGTVYLFSQRRLIQTYHPHNNGHPVLRRKPPAPFSRPNGNQERAAPLTAAQGAHRGVTVFIYEPPTTEKGKSLLIHIHLLFFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6V2</accession>
    <name>A0AAV4V6V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_299771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014026">
        <property type="protein sequence ID" value="GIY65758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13313" checksum="D9BD2D1C553A41C9" modified="2024-11-27" version="1">MIPSSIRSYHLLEKEETEDKEGRKELFANQDPSRVCSLTETYLTLKGGLQGSMTLSWLHFHLLSFGSQDDCSCAAFAAGVFFFFFLIATFVLVGTSMTRDVVDDVLGRRSFVAPFNAGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7R3</accession>
    <name>A0AAV4V7R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transient receptor potential cation channel subfamily M member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Trpm2_1</name>
        <name evidence="1" type="ORF">CEXT_616631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014064">
        <property type="protein sequence ID" value="GIY66054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14905" checksum="DABE3C092DEEB668" modified="2024-11-27" version="1">MEVVTHRNYLEVVLYLPDADVILPGGYVSTENTYFTIQTLFQCDKRWESELDMIDFFNSLSKEQVQGSISKTDISESTSSRRSLAILDTLRKASLTKVKKIVSKERDENSDEDITQPFIFERIKRLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGY9</accession>
    <name>A0AAV4VGY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_770431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014566">
        <property type="protein sequence ID" value="GIY69666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7460" checksum="235E1881BCC250DF" modified="2024-11-27" version="1">MPLNALTGAPVELTPDTRSTPCYYLAGVLIVVNARDIWAAGTSLKPQMDEPKCRWGLNCNHDPLLHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVV8</accession>
    <name>A0AAV4VVV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_504051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015172">
        <property type="protein sequence ID" value="GIY74143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11039" checksum="0B3115DA435E032F" modified="2024-11-27" version="1">MRELLVGQFYIESEFQRFTLASSVPKKSESLGAGTPEAAELFIAARVRTESVVICTGQLNCRSGINWLGDFCRKMHFVRNQERLMKILADDLRGTARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2F4</accession>
    <name>A0AAV4W2F4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_7551</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015498">
        <property type="protein sequence ID" value="GIY76568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2F4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051384">
        <property type="entry name" value="Mth_GPCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47154">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47154:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY76568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13665" checksum="9C0C79A091DB6054" modified="2024-11-27" version="1">MSYDIMKTMGMVKADTNKTSKFWKYSVYAWLMTMACVVPAVVIDLSDLVPEVYKPKFGVKKCWLTGQIAFLVYFNLPVGLTLLANCIFFMVTARTIIRVRNATAILADNRHKKGKYYNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W435</accession>
    <name>A0AAV4W435_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_95991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015536">
        <property type="protein sequence ID" value="GIY76805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W435"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043405582" evidence="2">
        <location>
            <begin position="26"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY76805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15563" checksum="F57E9D7095D19F40" modified="2024-11-27" version="1">MSLIFTVNCLLIFCYPSSITKPTQSIFKTVTSPIRHSSGIVPSDFPSTDIDGQPESNTSIFIKRKRGEKSSRKPIYQTRKRVRERKMPLCSRTMRNKSGTRLPSGDSWVHYSVRKATKKSSKEGGVIKQRLGVDRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6Y9</accession>
    <name>A0AAV4W6Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_50541_1</name>
        <name evidence="2" type="ORF">CEXT_189761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015718">
        <property type="protein sequence ID" value="GIY78128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="1">
        <location>
            <begin position="189"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="333" mass="38146" checksum="A7FD21BB169164F8" modified="2024-11-27" version="1">MDSIEVHIFSDASIVAYGAVAYFRYVNLRGEVGTSFVMSKCRISPLKKLSLPRRVFLWTDSEICLCWIKGSAREWKQFVSNRVLEIQDCTSPDRWKFCPGLENPADKLTRGENSHTLLNDSVWWQGPVWLRAWVKRFVAKLRKITCESGTLSAAEIKEAEEYWRNLACQRTIGASGIINEKHPAILPKSKFTDLIIMSEHEKSFHSGVVSTLSRVRNNFWLPRGRQVVKKVISECLICKKYALKPTKQLTGQLPRDRVVESPPFAVVGIDFTGAITIKAGDQSCKKVYIALFTCAVTRAVHIEVVSDMSVKSFIFALRRFFIKKRWLQNYLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSW0</accession>
    <name>A0AAV4WSW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_86181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016605">
        <property type="protein sequence ID" value="GIY85025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="289" mass="33109" checksum="6FCB7E0D59074AFE" modified="2024-11-27" version="1">MFKQDLCLRIFHWLGRWDIYETAIDWSWPLITQEESSSPSRFPARRIDLPAPRLDAFPESGHNREDLRLLGHHIYIGYTLETHVCIGKLYLNIALICLDRADSISTINALSSHLMGSIKGIYYSYSDCTLCCNTTDINLKDSSTVSTSNGFPMSRTLPHHSIKQKLHANPTEYPQPSNCAKPPDIVNLKKLRILNAQHRFSSPEIPPPAAKSSPAPIKKFHQRDVIRRNWVGCPPNKNLTVVFVIHRQKRQQEHQQGIDGRGIRDRPNNIAAQPRPPHRKKDPLFLFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTA6</accession>
    <name>A0AAV4WTA6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_566991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016718">
        <property type="protein sequence ID" value="GIY85947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11573" checksum="2F4E06620D63FB10" modified="2024-11-27" version="1">MTSSNIDDVICLLLQKRKLLSHAQPKHTDRATFVKFASVLLHLFLSCVFRNLTDFLDDAQLFLSFCGPRLKFGLPDVCEIHSKLMPWMKRMNFGGRHSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3J8</accession>
    <name>A0AAV4X3J8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_317901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017054">
        <property type="protein sequence ID" value="GIY88354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3J8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11649" checksum="5BE7AADD2B93126E" modified="2024-11-27" version="1">MVILNDSITRKWLMANYSVVWAFNVLYGFENKRRCTFKLVAKDAEFILYRRRFLMKVTCTGGPVGYPHYPCNNYQLPNRAEMMGRTWKGCFKSIFIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8Q4</accession>
    <name>A0AAV4X8Q4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Insulin receptor substrate 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Protein chico</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">irs1-b</name>
        <name evidence="13" type="ORF">CEXT_441741</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. May mediate the control of various cellular processes by insulin-like peptides. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains. Involved in control of cell proliferation, cell size, and body and organ growth throughout development. Also has a role in a signaling pathway controlling the physiological response required to endure periods of low nutrient conditions. Insulin/insulin-like growth factor (IGF) signaling pathway has a role in regulating aging and is necessary in the ovary for vitellogenic maturation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Bindings to phosphatidylinositol 3-kinase and SHP2.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017438">
        <property type="protein sequence ID" value="GIY91641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005158">
        <property type="term" value="F:insulin receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008286">
        <property type="term" value="P:insulin receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048477">
        <property type="term" value="P:oogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01257">
        <property type="entry name" value="PH_IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01204">
        <property type="entry name" value="PTB_IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039011">
        <property type="entry name" value="IRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002404">
        <property type="entry name" value="IRS_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10614">
        <property type="entry name" value="INSULIN RECEPTOR SUBSTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10614:SF13">
        <property type="entry name" value="INSULIN RECEPTOR SUBSTRATE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02174">
        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00628">
        <property type="entry name" value="INSULINRSI"/>
    </dbReference>
    <dbReference type="SMART" id="SM01244">
        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00310">
        <property type="entry name" value="PTBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51064">
        <property type="entry name" value="IRS_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0221">Differentiation</keyword>
    <keyword evidence="4" id="KW-0341">Growth regulation</keyword>
    <keyword evidence="7" id="KW-0896">Oogenesis</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PH" evidence="11">
        <location>
            <begin position="22"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="IRS-type PTB" evidence="12">
        <location>
            <begin position="138"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY91641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="26886" checksum="C4A13994B7A068D4" modified="2024-11-27" version="1">MSDKKEERNGSSSSSGSGPPSDIKKAGILRKLKTMKKKYFVLRNESENGAARLEYYDSEKKFKTGGAPKRTINLKTCFNINRRIDAKNKLAISLYTKDDCFSVVADSEQSQEEWLNAMLELQLDGPCLNGGARLRPKFEHVWQVTVGDKSLASSRNMKGLYRLCLTPSALALVKVDQTDRPETLEFPLMSIRRCGHTNNYFVIELGRSSITGAGELWLETEDGVIAQNMHEVTLNAMKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X942</accession>
    <name>A0AAV4X942_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_685821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017383">
        <property type="protein sequence ID" value="GIY91119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X942"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10452" checksum="2AA14D24EEEA9920" modified="2024-11-27" version="1">MIPKTKQTTMKKNPGVNELPIPDMQFKDKFERLASCQVKSRCCVDRSKTEDGSLNNSKNFLKQEAQGEEMINLARIKFLGQLEREEKRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB96</accession>
    <name>A0AAV4XB96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_507811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017510">
        <property type="protein sequence ID" value="GIY92186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11299" checksum="2357E5F01393CB9B" modified="2024-11-27" version="1">MIWDQKGKKYPVFESLVLFCLLVFLARSRFVDYYLIRFGVTRFPYLCSWLLIVIIIDHSQAVVAERRHTSKCLEVLCEKPQVLKAVSSHKNRPLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBZ3</accession>
    <name>A0AAV4XBZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_719911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017416">
        <property type="protein sequence ID" value="GIY91469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13147" checksum="B758E87D5B0F846F" modified="2024-11-27" version="1">MCYKPGYPMPSLISTFGKYSGLLIRIPILVQFPIFKTQCAILPGYFVPRFPHLENKMCYKPGYPMPGLISTFGKYSGSTHQNTLSLVQFPIFKNTMCYPSGYFVPRVSTFGKQDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH82</accession>
    <name>A0AAV4XH82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_126191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017733">
        <property type="protein sequence ID" value="GIY94018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14586" checksum="E31F30771A06B8FB" modified="2024-11-27" version="1">MINPNRCANKKAFFSGKMIAIKTHFSGVKKAVWDDGLLYRERVEEKIPNCATAQPSMLNPNRCAKKKAFFSGKMIAIKTHFSGVKRAVCDDGLLYRGRVEEKIPNCVTFSPLRELFLCTAVTVGKNVFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJS1</accession>
    <name>A0AAV4XJS1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metalloendopeptidase</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_753091</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3 4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01017906">
        <property type="protein sequence ID" value="GIY95392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF883">
        <property type="entry name" value="ZINC METALLOPROTEINASE NAS-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="5">
        <location>
            <begin position="16"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY95392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25395" checksum="F1A02C173B86B49A" modified="2024-11-27" version="1">MKTIDNVKKRIPSFVAGIKDPRFRWPKYQGFVYIPYGIDQYAGHLRQVVQAAVEAYRRYTCIRFVPWTNQRDYIRIFSGIGCWSLIGRNGGEQKLSLGQGCVYVGLAIHELGHAAGLFHMHQRSDRNNYIYVYRQNVIPNQLHNFDVTDENREIILGPYDYDSIMHYGSYAFSRNPRGLRTMEAKNGHPLVEPWQKRGFTSLTSTVSINFTDAVNFYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK47</accession>
    <name>A0AAV4XK47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_768811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017864">
        <property type="protein sequence ID" value="GIY95038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11715" checksum="32D9AE97AA4E5EFA" modified="2024-11-27" version="1">MMNQSDQTPLRNPTISQFVDRPSEAIRKHACWPLCFIYSVMSRAITSIHFASALISGIHRAFLINSGRQLSTGGLAGHSGKEDDLEFIREMSTTPFFRFFVSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPX0</accession>
    <name>A0AAV4XPX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_235951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018116">
        <property type="protein sequence ID" value="GIY97076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043887427" evidence="1">
        <location>
            <begin position="19"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11381" checksum="2F6D4A84368EE076" modified="2024-11-27" version="1">MIKTLVFVLAVIAIATCSMNVIPQHNHHGHGIRTRFIGKAQGHVYGDYGYNLGNRYGGLASRGYGRGHIGYVLYGNGGLGNRDYAYANLGFGVYGGFTLGYESYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRA9</accession>
    <name>A0AAV4XRA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane and coiled-coil domains protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TMCC1</name>
        <name evidence="9" type="ORF">CEXT_355462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEX28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000657">
        <property type="protein sequence ID" value="GIY96434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019394">
        <property type="entry name" value="TEX28/TMCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17613">
        <property type="entry name" value="CEREBRAL PROTEIN-11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17613:SF14">
        <property type="entry name" value="DEMENTIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10267">
        <property type="entry name" value="Tmemb_cc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="267"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY96434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="380" mass="41833" checksum="AE67BE8ECD9307A8" modified="2024-11-27" version="1">MKRKSPLQQRRGGTSSDSNDSTKISTPHDSTKLNAPQHGNVSMSSPAVLHPPAFHVNLSPGLSAPSHSVVNNSADEWNNADDSAENDGAGLSGSLQSLGSAEGLNFYDLDETDGSSHVVNVQRTKAAIEHIQQKIIRTKELIKLEQTARDENVNEYLKLATNADKQQLQRIKNVFEKKNQKSAQLITQLQKKLENYSKRIRDLETHGIPRGVFRDMGQGIKNVMSKPREFAHLIKNKFGSADNINSMNKSEECNDEPELNIHGSALSTHSTRYTSDEENSSVASESGQNPNAGEAQVHSAVPSPHHHAALQSLPSGTESSTIHSIGPASFDLEPILQELRSQRDEYQHVVEEIESVKGQIQQESTFSVKHCRKKDIVMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRW6</accession>
    <name>A0AAV4XRW6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_706551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000715">
        <property type="protein sequence ID" value="GIY96920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13403" checksum="173509B390F4A547" modified="2024-11-27" version="1">MLLLLFIRPPPVARRVLFRSSDTVSGPMWVRPFFSRESTRDVFCWGGSVSESLLRTSLWRSECIKEAPLDIVSCLLFRGVRSLYRLHVLYTIRLEELGQREQKQVLKSYDFILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSJ7</accession>
    <name>A0AAV4XSJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_233061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000708">
        <property type="protein sequence ID" value="GIY96829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14706" checksum="EAA1E41E2EE41AF3" modified="2024-11-27" version="1">MHVIISFERGGFSAPISFKEEIHPFPRVACQRLEKQQKQFPPVRDKTTGAEIGASKTIFFLFLLTNRCSPPILLLADIGNRRLERKRFPLPPIPFLPFQPSLFRMHRSRRGRKWFFGTGSCRSWAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUV2</accession>
    <name>A0AAV4XUV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_485281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000793">
        <property type="protein sequence ID" value="GIY97533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12902" checksum="3711C108DB61DBB7" modified="2024-11-27" version="1">MSATKERKAMKRLNAQLRPRNGSFSPPTPPPSHPLNQAFFSTDIGEHLPGGWRAVSYVLSAHHPKVHRVHFPAPLGLTRTSEVHKHECENSLTHLLKILTNFASTASNTNFIFLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVM5</accession>
    <name>A0AAV4XVM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_197811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018341">
        <property type="protein sequence ID" value="GIY98807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11956" checksum="6994A9B9CCB42808" modified="2024-11-27" version="1">MRNISAQVTFAETLIKRLFAKFCTGIFKRSTINELIKCFARECIPNVHFDVGKLIAAYVRELEVQFQEICIPNHPRKRMVISASYPRLFCKFNKLRNGHYLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVS7</accession>
    <name>A0AAV4XVS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_629881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001010">
        <property type="protein sequence ID" value="GIY99146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7820" checksum="CC237F5E0EAB370C" modified="2024-11-27" version="1">MAPLQPIDVKEPGDDEPLLRRSQNFPAYKTLAEEDIALWTIADEQQEITRNTIANKENNVYKVDGKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWS0</accession>
    <name>A0AAV4XWS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_171071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018280">
        <property type="protein sequence ID" value="GIY98329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8590" checksum="B6CEF4E941D7CC73" modified="2024-11-27" version="1">MHLFLKGFEDDEFEGLNMLKSLMLSHNRIITLGSSLQKLVRLELLRVDSKPPPHTRQGADPGQSTRSLLGRQSFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y020</accession>
    <name>A0AAV4Y020_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_639901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018584">
        <property type="protein sequence ID" value="GIZ00766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y020"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043775126" evidence="1">
        <location>
            <begin position="22"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9699" checksum="680F84F389E1997D" modified="2024-11-27" version="1">MATSVFMLLYRIHIWPNTLWGCYIAPRINANYALYKQYTKREFFCAPPLKLNGLMANDSLGHQTANRDISDKKWDVAVTTESVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y407</accession>
    <name>A0AAV4Y407_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_623721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001224">
        <property type="protein sequence ID" value="GIZ00925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y407"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15242" checksum="97DB654C3BA26120" modified="2024-11-27" version="1">MCAIEKKKLAKGNDGQIDSLWFYIIKQLREVVLENRKKLSFLRKTFGVVPEFVIPLKNYLKLQFTYMDIDKDIPLQIVVKMYHKIFLSIAPKLSSLVASHTYVSSAQVAADNVANYSTYFTSKAPFISNEQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4N3</accession>
    <name>A0AAV4Y4N3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin carboxyl-terminal hydrolase 34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">USP34</name>
        <name evidence="2" type="ORF">CEXT_715881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001457">
        <property type="protein sequence ID" value="GIZ02416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4N3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="496" mass="56175" checksum="36CB3DF46AAC7327" modified="2024-11-27" version="1">MYGCRQYLANLRPQHHVPVTGDLVEDILSPDDGSCNSSHVSNKSEKNLADFDGEESGCEEELEQLAAHAQAQLNTHPMTQRLTNMACMYTPQLHGGKHPHHFIGRSPREVRQAMNHFELDSVCESGQTLLWDILQDDKIGQLGEGLAVEAEKNSMQSCLSVIISMRLLPKLFASFQQFRGSSDTYSVTMYSHKDEIQVRLHFLTCIFCTSGSPESFRLNHEQVDTLWQCLAQDPECADELFGWLLNQAKGKRATCSQYFIIQACSFGKNLFINIVLTLLVKALQEKKMPQLPPESTSMMALNLLQQLSSIAHLATASYDTPSSAADVSGMKQLWGIALRALNTDVSMAAIQYLNNYYINVHHGTLEKEEEFIQQCMENLMKASSDQSPESEENNLMIIQRALLLLKTHIEAFRRRYAYHLRRWQLNGCGVNSHRSSIGDKPASPLRIICQPAGLSEKTTIELQNCDTVADLRAEVTQWWEQLQAKHKRQYFRYEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y728</accession>
    <name>A0AAV4Y728_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_40831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001374">
        <property type="protein sequence ID" value="GIZ01959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y728"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9752" checksum="E2C1AACEB87654EB" modified="2024-11-27" version="1">MILERTLIELKKKRDKERKTGESRDAKDQPLPCAHSRSEVGFFIAWETSDRAVASGRGSSHFPAHEFCAPRCQVGRSCDFKSYFCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7U1</accession>
    <name>A0AAV4Y7U1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001600">
        <property type="protein sequence ID" value="GIZ03418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7U1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9642" checksum="EBF8D390FC89640F" modified="2024-11-27" version="1">MLHHKLLNVNLLTRECCRVQSQRRHAYRATGNSCTPDAEPHEGLTDNKICVIAENSVFRDALADCCPQTTPLSFCPRFAVAVCRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YA53</accession>
    <name>A0AAV4YA53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_13421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001692">
        <property type="protein sequence ID" value="GIZ04107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YA53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9958" checksum="0F947D3E4C85C0F2" modified="2024-11-27" version="1">MPTNMPTYPVLRNGLLADDFTAAYARSSRTPLKGTRINSEDAPRHYNLCLLMVMKHRNKVLERNCFRHCFCLFRIFDDAGYEMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD13</accession>
    <name>A0AAV4YD13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_631411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001685">
        <property type="protein sequence ID" value="GIZ04057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11536" checksum="6F670C233E6FD4E6" modified="2024-11-27" version="1">MRWVTSQCPRNWGASQQFGLGEELGGQNLWKKKYPPPPLRKTPINKQLSTPFPTNICPSQEARVGIKNKMPPRFPMAMINSSFQSHDNGKPVGRFQLTTNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MB50</accession>
    <name>A0AAV4MB50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_582221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002072">
        <property type="protein sequence ID" value="GIX69673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MB50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9236" checksum="190B2728E33EF22A" modified="2024-11-27" version="1">MNRLAMHPPPKRISSSRFSAGNIPVLGIIHNRRRPVCRRAPKWTLHNAQREHSRSTLYSYIYKDEDCFVDDVSSTACLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEC8</accession>
    <name>A0AAV4MEC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_36031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019689">
        <property type="protein sequence ID" value="GIX70630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9017" checksum="0F2DF739AB8D1BA1" modified="2024-11-27" version="1">MASKPKREFLAYPKKGHPDTLKEGSKIIAGGERKRKKILLIHPGKRKMGTKENKFGKKEGNVGCHGEETEAFGVLRSELGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGJ3</accession>
    <name>A0AAV4MGJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_632691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002177">
        <property type="protein sequence ID" value="GIX70965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14761" checksum="0BC98DDEB7372152" modified="2024-11-27" version="1">MLSTAPRKVEHPNPNPTSINHRRTMHFIYFLPNFRTLAVSCDFFFPANSQTKSIKGPHSDSPIHQTIFPLGREQAEPLPPRTEKVPELPPWPRRISSGRKCCNSEILLDCSCSQEVCKVTSKPSILHWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLI5</accession>
    <name>A0AAV4MLI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spaetzle domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_55428_1</name>
        <name evidence="6" type="ORF">CEXT_775261</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002335">
        <property type="protein sequence ID" value="GIX72665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005121">
        <property type="term" value="F:Toll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0021556">
        <property type="term" value="P:central nervous system formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032104">
        <property type="entry name" value="Spaetzle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052444">
        <property type="entry name" value="Spz/Toll_ligand-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199:SF12">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16077">
        <property type="entry name" value="Spaetzle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Spaetzle" evidence="5">
        <location>
            <begin position="385"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="100"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX72665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="481" mass="53745" checksum="662E8565E03494FB" modified="2024-11-27" version="1">MASLFGPALMFNPPGGPSTPARKDFNNMSPQRLHSTRYNGPIKRGGPPFLFIQPMTMSKRPRQSRRLVLTLPKDNIHILNAEAMPEKGQQFLPTTLTLSLRDNTDSEDNNKGNLRYSTTRSYASQIPSPPRQASRYHYGFVPVSQGDSDEEDRSSRKPGRWNKGEVSYEMDDLVGSSGGHVTVIKAHSGRQPKVLTARKVMSGGSSFKPMKAILIEPKEIEAKRVHVMEADSEKVTATKARVIAAPDSVATGYKAKVHPVSYKKGIVTKTKGEDWAASNLHFVKTEAPQDSSARHQDEDVPPMELQCGGTNDLGWCDLGPNYPSAEVSQIMEVCEELVNHMFIEVPENSGPMEDIATYSLSRNITNQGSKPYWPWKTHSTNYKRSLCEINREVIRPSFAQDMKGKWHVIIQTDAFPQRIALEVCKKPGEPCNSNDLCSKSKSQCVQKYSHHQLISFDPESAETCPYIRLYKFPTSCVCRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNK0</accession>
    <name>A0AAV4MNK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_522551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002458">
        <property type="protein sequence ID" value="GIX73929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12214" checksum="70FA83791D8ED1B3" modified="2024-11-27" version="1">MKTKIFNQGRLIGKKLARKHTKRKKNKKIPTTMHPARCGSSATLLCRRSSLFLFLKRLYNGGHLHAVEEINKRFFTHSAQIIRLHCIRARGFTLSDERIAEEEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MW79</accession>
    <name>A0AAV4MW79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_574061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020283">
        <property type="protein sequence ID" value="GIX76792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MW79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="41" mass="4643" checksum="12CCDB6D9E11941A" modified="2024-11-27" version="1" fragment="single">MPYSKQGEDLVEALLLGAELHALHRSGHCRSLECLGRYLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX23</accession>
    <name>A0AAV4MX23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020209">
        <property type="protein sequence ID" value="GIX75926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8431" checksum="BE3BD92DACCF7E35" modified="2024-11-27" version="1">MEKSKTRLVNHGAVERRKTCAAANRNRAKKKLPSLPKRFLYERDKILTPTQSRPALYFVEFLSDPNQFCRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXW8</accession>
    <name>A0AAV4MXW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_215361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002740">
        <property type="protein sequence ID" value="GIX77326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="36" mass="4123" checksum="523AAFBBF4CBAC9D" modified="2024-11-27" version="1" fragment="single">GNYRLQNEVSYKLNVVGYTTKTTDDYDDTTTTPYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY05</accession>
    <name>A0AAV4MY05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_318221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020284">
        <property type="protein sequence ID" value="GIX76821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8029" checksum="126723E1DD790D9A" modified="2024-11-27" version="1">MAAAKSWAAVKVWRLQKLGAVKVCQVQKLGAVKVWRLQKAGRCESMAGAKAGRCKRLNLQAKLTRPDGYGMSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYU1</accession>
    <name>A0AAV4MYU1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyoxylate reductase/hydroxypyruvate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GRHPR</name>
        <name evidence="6" type="ORF">CEXT_413191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020355">
        <property type="protein sequence ID" value="GIX77717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008465">
        <property type="term" value="F:hydroxypyruvate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05301">
        <property type="entry name" value="GDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000026">
        <property type="entry name" value="Glyoxylate/hydroxypyruvate reductase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF277">
        <property type="entry name" value="GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="26"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="5">
        <location>
            <begin position="78"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00073306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX77717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="291" mass="31652" checksum="5590864ABE24D87C" modified="2024-11-27" version="1">MSKPKVLVTRPDVPVEGLDLLKEKCEEVIETAGPQLKAIATMSVGYDHIDTKTCKEKNIPVSNTPDVSTDSVAEMTVTLLLAAGRRLIDAAKAIKNGDWVYSWSPLWLCGQGLTNATVGIVGMGRIGQGVMKRILPFGVSKVLYFDVFHPIKPAEDMGAQYVEFEELVKQSDFIVAMCNLSDQTRNLFNKKAFDLMKPTAVFVNTSRGGVVNQEDLFDALKNKKIRAAGLDVMVPEPLPKDHPLTTLENIILTPHVGSAEVSVRVQMAKLAAQNILAVLDGKPMVSPVPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZI4</accession>
    <name>A0AAV4MZI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_10751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002743">
        <property type="protein sequence ID" value="GIX77346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8978" checksum="3AE5CFCF0ED7B1CE" modified="2024-11-27" version="1">METFILVNSAWRKRQQESHNHDWKHVNTKGIISELTNGQVAQCPVSGGILRHCGRGETAGGSVGFAPKKGKLRMVTYEKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZV3</accession>
    <name>A0AAV4MZV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_493551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020367">
        <property type="protein sequence ID" value="GIX77971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13605" checksum="C2751DB3E49D38CE" modified="2024-11-27" version="1">MSWMHKALTPIARKEVIVVGNKAAIRARKSVPENPHKAAEGNKIGLANTSPRINISPTHISVFKGFMQIQGHKGMMRDVVVCLIVSCTIAQYVVGYIPRSIQCAGRNGEREATFGGVAFSVAYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5J6</accession>
    <name>A0AAV4N5J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_714951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020434">
        <property type="protein sequence ID" value="GIX78689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10018" checksum="0F20998D0D319424" modified="2024-11-27" version="1">MEGGQEEVGVVLAEDANVITSGQTIFSLRVGILHFARQKGCTFINALRTDEQIQGLAHLAFKHRDVFANGKSETESECGNHYLAMNRVGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGS3</accession>
    <name>A0AAV4NGS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adhesion G protein-coupled receptor L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ADGRL1_0</name>
        <name evidence="7" type="ORF">CEXT_682501</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003338">
        <property type="protein sequence ID" value="GIX83520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011:SF347">
        <property type="entry name" value="FI21270P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="341"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX83520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="433" mass="48980" checksum="BA6E9F776884AFB2" modified="2024-11-27" version="1">MTLIRSCDAKKSNSWWYYAVAYIVPGIITGISAVIDPSSYGTDHYCWLRADNYFVFSFVGPAVSIIFGGLVFLCIALCMFYHSISSTTAVKGSDNANFMKYRAWNRRIKEEVKKLFLHSSCFKQRKQEPQNSSEIVNSGSNSRESDPQEFWTLPKERTPASSSNIALESSTLPARCSFNESDDGVRPQNAFWMPRGNSTWKPAYYSSKNDAEEQDVVSVGFRRYNTSNVKDKGRQFFVTPESNGQFLDHIYETIDDETVANEDEAKKSFQACQRYPPPENYYGDHSDLSQHSSSSYGYDQQPLIIVGLQNGPNASQVSYLAPTGSHVNLHSDHSNQLWEQNQNQSFRRQRSPSEKSGTLRTSNEGSRHKTSSEKQVYPQKGSSELWETPLPDLLRSPPESTVVLAVLDGDKVVNRVQQDDVLIKPQYKLSTYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJR9</accession>
    <name>A0AAV4NJR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">AVEN_126441_1</name>
        <name evidence="13" type="ORF">CEXT_226861</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020926">
        <property type="protein sequence ID" value="GIX84063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX84063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="336" mass="38662" checksum="45366CB7262EA812" modified="2024-11-27" version="1">MTLYFRAYQSPRLARVIYKLLTERNHDQKKKLGHSTDMIQSCIFNGIPKSWRRGVRTVSRHGIFLKKIIEHSYDPDYGNCYTIPPRNSKGQILEAREADFWQEANDLSLLVDLETDELMEKKRHPGIIVTVHDINTLPDIHTDGHMIGAGISYTLSVQKTSVHLLPLPYKTNCTNYLKLPWHKDINRRLTSRLCTVGCSQYYQFQKCKYVTQNLSLFYNELPYDPKKITEEDLRCAEAEELRTQDYCRSICGLPCKDTVFVVTSSSTPLSIKETTMELFSYLGGYSGVVGFSLLTVYELIEILFNIAKFAFAEAPGWYSTEKVLRELPIPRSMAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPY2</accession>
    <name>A0AAV4NPY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Cytochrome P450 2B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">Cyp2b1</name>
        <name evidence="17" type="ORF">CEXT_614911</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021098">
        <property type="protein sequence ID" value="GIX85848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIX85848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="436" mass="50007" checksum="3D8B6B6B5FA85FC5" modified="2024-11-27" version="1">MEEMKKKYGDVFSFTSTGRLYLHLGSVKSLREAHINKADCFEGRCTDFGVLSRFFEEGVGVVNGEPWKELRKFFLQNLKERGIISVKHSLSGSMYDAIKSAVDFIKDKKGEPINILELVNNKCTTILTKMFFGDNGVTEEQIREFIGLYYTVMMCMVPTNLILSGNFARYAIFPFLKVFKEATACDKKIEKMLYAIIDEHKSTYDEEHIRDIIDDYIKERDLRRSKDDPTAKHFTDKALMASLKEFVGDGIIAVSSFVSIIIKILVEHPEEQKKVYEEIIEIVGVDRQPTVEDKSKLTYTNAFILEASRTSDFFPFVPCLECTKETTLRGFRIPKGTITLMNLYSSHYDTEVYEDPHKFDPSRFISKDGKRRSELPILFGVGRRSCMGEGFAMMEVFLFLTTIVKNFQLSFADGVKKSTNDDLFTGKLRIVAHPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZA6</accession>
    <name>A0AAV4NZA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_202001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003885">
        <property type="protein sequence ID" value="GIX89749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="13117" checksum="DB451F372AD18201" modified="2024-11-27" version="1" fragment="single">MSQNLFTFMEDDIYVPTKYHVRMKLSVIFEKLFQSKTQERFGLIALILRIGWQFFLPDSSVQWRRWRDFPGRNRFSANRRIGLAFGRRRDGSRFVGSAFSWSLFLGLLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5Z6</accession>
    <name>A0AAV4P5Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_535021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004128">
        <property type="protein sequence ID" value="GIX92454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="27130" checksum="1B2386EBBE1CCCA7" modified="2024-11-27" version="1">MQGCERGVPQQKILARCEVSPYGSMRCSRGSQNRVDSASNDIAGTNRPAYFLLCLCPRIESASPRGPVNAERNFHAQFRDRHHAYVKRNLQLLFIEIRRLDGEYKGVREASRIRSYLLGAKVSPYDSMRCSRGSQNRVDSASNDTAGTNRPAYFLLCLCPRIESASPKGPVNAERNFHAQFRDRHHAYVKRNLQLLFVEIRRLDGECKGVREASRIRSYLLGAKYHPTTACVAVAALKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P811</accession>
    <name>A0AAV4P811_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_624161</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021714">
        <property type="protein sequence ID" value="GIX92730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P811"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX92730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11429" checksum="74FA3C0038D9BE2A" modified="2024-11-27" version="1">MVVAFDLFSTSSRTKIGAYDIPEDTIVMPNLWGVHHDAEYWENPFAFRPERFLKDGRAVRPRAFVPFSCGKNRICQRKSGSSAQCLRDGGKKREFFLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P972</accession>
    <name>A0AAV4P972_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_308221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004300">
        <property type="protein sequence ID" value="GIX93817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P972"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9820" checksum="13B0B5BF8C0573B3" modified="2024-11-27" version="1">MIAKIEKTNLIHSYMLTITAGHLVVRQTGIGGCIPDGNTPQRPGVIFWVQGRTSSSSTSQGPEKLCFCPSARWSFWALLSCPNPFWEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAP3</accession>
    <name>A0AAV4PAP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate receptor ionotropic, kainate 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GRIK2</name>
        <name evidence="7" type="ORF">CEXT_593121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004107">
        <property type="protein sequence ID" value="GIX92217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043697051" evidence="5">
        <location>
            <begin position="21"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Receptor ligand binding region" evidence="6">
        <location>
            <begin position="22"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Receptor ligand binding region" evidence="6">
        <location>
            <begin position="149"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX92217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="295" mass="33225" checksum="DFFD74F0607A599D" modified="2024-11-27" version="1">MIPYFLSILILFKSSSEVECVSVAVCSLLETGIAGVFGPQSSVTSMHVQSICDAIDVPHVETRWDFQLQRADMSINLFPRPSVLSHAYVDLVKIWGWRSFSLVYDEHEGVIRLQDFLKEAQINDWRVQLYQFRPPTLIGISSGESNRLAQQVGMMTESHNYLITSLSDKRLSVTSNTTSFQDLHTIDMEDFKYGKTNITGFRLVDENNADLQALVVELNTKWSGAIRKLDFPIKTIRTETALMYDAVQLFAKALQDLDGSKSIYFPPISCDSGLRGLDGSSIINFMKPVSCDHFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGA0</accession>
    <name>A0AAV4PGA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heart- and neural crest derivatives-expressed protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hand2</name>
        <name evidence="8" type="ORF">CEXT_659561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004549">
        <property type="protein sequence ID" value="GIX95674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000010">
        <property type="entry name" value="Scleraxis bHLH transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050283">
        <property type="entry name" value="E-box_TF_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23349:SF68">
        <property type="entry name" value="FI14601P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="132"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX95674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="24999" checksum="B30997F0391AA7D8" modified="2024-11-27" version="1">MIRSNVFESRSYRTKSQPNEKFFLDMKKRAHKPNQVASLHISIALHTQLPSSIPWPTDSLHAVATPLSSGWSLIPATSETNQSSSDPAVYIQHEPGGEITSKPFAVRRRLIPNTSTAIELHRQRIKNRAGFKRRVTANRKERRRTLSINNAFAELRECIPNVPSDTKLSKIKTLRLATSYIAYLMDLLAQEDPNRAPQGGFKAELCKKSLNPEKKEERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PID0</accession>
    <name>A0AAV4PID0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_48122_1</name>
        <name evidence="2" type="ORF">CEXT_802341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004529">
        <property type="protein sequence ID" value="GIX95501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PID0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9813" checksum="14122308E9A9F8C7" modified="2024-11-27" version="1">MEHEDKQIASVETSHLNGFSDSDAHDIKDLSPIGPVVESIETNSNKESVVQSDMPMLLQVFKNAYDQRLASINNNPDLDQNKKMRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PMK7</accession>
    <name>A0AAV4PMK7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_690211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004937">
        <property type="protein sequence ID" value="GIX98632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PMK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14554" checksum="BD710A0E02884B53" modified="2024-11-27" version="1">MNLDLYLTCGQKFEKVLHFKLTARDPRINMSTIQLSLLNNAGGKTECVKGEVWFNLPEKLHSQLTFQTTRNRLMAAKDVYLPNDVLSVLCIIILHVYCQVRKYASRGIQPYLTSLKVDNASRTLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1L1</accession>
    <name>A0AAV4Q1L1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_332061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005389">
        <property type="protein sequence ID" value="GIY01925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1L1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24733" checksum="E66CDFA099B7F77E" modified="2024-11-27" version="1">MNPIYRLYFWIVYRYIKSPLSLTCVETWRGTQEDGHVRCQNVNAFNCCRFFLPFLSNSSSFARRSGRNGVERKVATRFTGDTPKFKDTPGRNPKRMVRGLGKGALTICKRGHLSVPPECTTDKILNQAMKSRSRVRGMRLGNMELLNELAAYFEEKVLSTGIVSWIPTKYSKRKSQQVSESEARVSLRLSFLTSMKLQIRSDLYGKMRTIAIRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7W0</accession>
    <name>A0AAV4Q7W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_268791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005743">
        <property type="protein sequence ID" value="GIY04694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11703" checksum="2993A32E647E903E" modified="2024-11-27" version="1">MERWKVRKKGAAVMGNNILKEKSDGNPRSGQLPSNCFEISKTGINAIMSNKSDVLLKLSYPPRLIGCSVLRIRCFDNLETQMILHQFSNHPEYFVIALASYSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q876</accession>
    <name>A0AAV4Q876_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_598291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005718">
        <property type="protein sequence ID" value="GIY04524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q876"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11996" checksum="C1E03A86F3DF665E" modified="2024-11-27" version="1">MLTLDSEGSFVFDCCFLGKAGLADLHSSLFPLSLGKGVKWRVLMVTFRASFTISDKPAVILCPSSHHVVRPVDVILSFRTRIRILHRLGESMAFPRFVHLLAELKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q970</accession>
    <name>A0AAV4Q970_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_585381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005766">
        <property type="protein sequence ID" value="GIY04902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q970"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8811" checksum="0378CC80EC352F44" modified="2024-11-27" version="1">MAAEDTIRGRMLDFKAKVSDLKTGKADKFVNSSVYSIPFYVTEMHQSISPVTNNSPFNDNPEESQVNGQPWAILMQSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBT7</accession>
    <name>A0AAV4QBT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005847">
        <property type="protein sequence ID" value="GIY05465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="210" mass="24685" checksum="20FF857710217F59" modified="2024-11-27" version="1">MHSSSSNRYLIFSFNSNNVLRLKIHVCPLATVTESNAVNVNAVDDTIQFGNESVELLAYNIERHHVHVDVNIERHHVKRSHVHADINIERHHVHADVNIERHHVRADVNIEKHHVKRHVNKTHHVKRHLHVDANIERHHVKRHPVHVDVNIERHHVRADVNSETHHVKRHLHVDANIERHDVKRHPVHVDVNIERHHVRADVNIRNAISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCY8</accession>
    <name>A0AAV4QCY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_600361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006066">
        <property type="protein sequence ID" value="GIY07192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="57" mass="5975" checksum="B6C8B54093C37544" modified="2024-11-27" version="1" fragment="single">VIIGNSVANTPPADSAFSDRWPSSFPLNLFEGSSAAVVPTIRPTENRGSALIFKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QEE4</accession>
    <name>A0AAV4QEE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_455161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006150">
        <property type="protein sequence ID" value="GIY07759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QEE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14523" checksum="E8F3E546B2AA4582" modified="2024-11-27" version="1">MAGGQHPNQKSARPTTCWTDNDGAQPQALKSLSFTCRYFSNILGSKEKKRGYYTSVELFPGRHATLTQELDPLTTKCVSAITHPVKDVMAGGQHPNQKSARPTTCWTGNDGDQPQALKSLSFTCLYFSNILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIP1</accession>
    <name>A0AAV4QIP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HNAJ_LOCUS8404</name>
        <name evidence="2" type="ORF">CEXT_337751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006326">
        <property type="protein sequence ID" value="GIY09040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33332">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="279" mass="31553" checksum="FBD3D14E20CEF17A" modified="2024-11-27" version="1">MSRVFKRQLGPCRDRSEDLPENVKNIFCSSFSMHELNMAQNGFEKSQAIKDALDSKQVLTAIAVDLKSAYDMVWKENLLFKLNNRGISGHLLSWIKSFLSQRLCRVRSNLSKFGLLQTGLPQGAVQSCILFNAYINDLVQKLKSIHGVKCLLYADDLLIWTVTPKKNLVPLTEKLLNQAFTNPGKVVRREQHENGDALGQPSTPRIKTFVLPVITFCCEPLISASKQVRKSLETFHNQALRLITGAVKTSPIDAMLLCTRNWPLEKIIEEKALVLWEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPA3</accession>
    <name>A0AAV4QPA3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006593">
        <property type="protein sequence ID" value="GIY11020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11539" checksum="5436D868F75A7766" modified="2024-11-27" version="1">MILIISLFRVEGNSAFRMKDYTKSRKSRLLIRSSGIPINNTQDFNYYHKIICKTFPKQLLQPIQLKEKARVLKINPRSQVKLKCETFSFISNFTGFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4M7</accession>
    <name>A0AAV4R4M7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_177331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007392">
        <property type="protein sequence ID" value="GIY16579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17751" checksum="4B7698AD7CFD496B" modified="2024-11-27" version="1">MKDKLYTIFRDIKFAFIHCDDNEGWTKKGIRKVSANLSVHMKLFTGIVINDHHRHPSMPGYAYPCCGRNDGIQMAPILQGLGSYILADRKEILVEVHCLTSDRNLLGINCLMSDRNLFLEVHCLTSGIWGGFVLLKSSMHDFLISELRECSHDVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RR48</accession>
    <name>A0AAV4RR48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_237641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008221">
        <property type="protein sequence ID" value="GIY22937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RR48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="11874" checksum="6F64A01DBF5A4F25" modified="2024-11-27" version="1">MSFHCERTKVPTLNSITSYAFWGANIPADHLQEALIHQSVSVLTTPNHFSNETLWVKLSPSESALTTAHSGQWMGSVADDRLLCSLNVFPGPFEAGSFIISPPHVNPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXZ4</accession>
    <name>A0AAV4RXZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_342301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008729">
        <property type="protein sequence ID" value="GIY26758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16606" checksum="A9F5AB399BCBAB06" modified="2024-11-27" version="1">MLEFTLPPILVAIMPVQERHLSAKELDSENGRNKLCKMISALVEPETLVAVKIDIFTASLEFTRRILTFKVVFEMQERKYAWVLPAVNFHSFNKMLLLLLLQYSYFFPEVWSNFGRNYLRNETLRVIILKSNFPLPFEMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZ15</accession>
    <name>A0AAV4RZ15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transportin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tnpo1</name>
        <name evidence="9" type="ORF">CEXT_561711</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008606">
        <property type="protein sequence ID" value="GIY25944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZ15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="37"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="324"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY25944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="888" mass="100354" checksum="D42F1D2385A94E11" modified="2024-11-27" version="1">MRESMALAWQPQEEGLREILKLLKESQSPDTATQRAVQQKLEELNKYPDFNNYLIFVLTKLTTEDEPTRSLSGLILKNNVKAHFHQFPPEVTEFIKSECLNSVGDPSPLIRATIGILITTIASKGELTNWVDLLPRLCHLLDSEDYNVCEGSFGALQKICEDSAEYLDSDALNRPLNVLIPKFLQFFRHSSPKIRSHAIACVNQFIINRTANLFHLASDEDPEVRKNVCRALVMLLEVRMDRLIPHMHHIIEYMLMRTQDLDEGVALEACEFWLSLADEPICKEALSPHLPRLIPTLVRGMKYSELDIILLKVDVEQDDMIPDREEDIRPRFHKSKTHSQKHMDDNTENDTESDDGLDDDSSLSDWNLRKCSAAALDVLASVFHEELLPVLLPILRETLFHQDWEIKESGILALGAIAEGCMTGMIPHLPELIPYLISCLSDKKALVRSITCWTLSRYAHWVVGQPHGSYLKPLMTELLKRVLDANKRVQEAACSAFATLEEEACTELVPYLSFILETLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKQEYISLLMPPLIEKWNYLKDDDKDLFPLLECLSSVATALQSGFLPYCEPVFRRCLSLVEQTLNQTMANVSNPEQFEAPDKDFMIVALDLLSGLAEGLNGHIETLVMSSNIMQLLYQCMQDSMPEVRQSSFALLGDLTKACFQHVSPCIQDFLPILSQNLNPDFISVCNNATWAIGEISVKLGKQGQDMKPYVLMVLTQLITIINRPNTPKTLLENTAITIGRLGYVCPAEVAPYVTAVYSPPGVCTSLRNIRDNEEKDSAFRGICSMISANPGGVVVDFIYFCDAVASWVNPKPDLKHMFHEILHGFKNQVGEENWTRFCEQFPLPLKERLTANYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZL2</accession>
    <name>A0AAV4RZL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_81383_1</name>
        <name evidence="1" type="ORF">CEXT_736551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008698">
        <property type="protein sequence ID" value="GIY26549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10533" checksum="089B49A921D5F32D" modified="2024-11-27" version="1">MFQIPDEVSPKHCHFSTIYPPFQAKVAFTPDLSLLIGSVANVLTFRNYTASPKMAFNVKPLQSLKVLLSACQMAIWWNGNNPSAFGIPGAMFRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4G1</accession>
    <name>A0AAV4S4G1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Gld_60</name>
        <name evidence="3" type="ORF">CEXT_453481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008920">
        <property type="protein sequence ID" value="GIY28214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF227">
        <property type="entry name" value="GLUCOSE DEHYDROGENASE [FAD, QUINONE]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043495422" evidence="2">
        <location>
            <begin position="22"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY28214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18255" checksum="3E2EB887DF192123" modified="2024-11-27" version="1">MGLLQYLPTLLPFAALFYMRAQDTFVPFTKDYWDTEYDYIVVGGGSSGAVIASRLSEDPNVKVLLLEAGGPENQITDVPLVAASLQQTPVDWAYQTEPQQASCFGLKGRVGLPFLNMHFAIYSITSLNNPSSEVGSALPDQLDIVVPSQYHYTLSSLYSSCQLMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8S1</accession>
    <name>A0AAV4S8S1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_704941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009054">
        <property type="protein sequence ID" value="GIY29334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.30:FF:000040">
        <property type="entry name" value="Agrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.30:FF:000072">
        <property type="entry name" value="Agrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003645">
        <property type="entry name" value="Fol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00274">
        <property type="entry name" value="FOLN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="62"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="156"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY29334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="273" mass="30512" checksum="7DDEED5D4361378A" modified="2024-11-27" version="1">MNENMEAIMISCWIRGGGFKHLDAILRYVSSIQVQCSRPVVITTDPCEGVECPATQVCQLDNHRNPICRCNAICSPDFRPVCGSDGKTYINECSLRVESCKSRRSLRIIFNGECSSEPLCAKDCPSCIVAFRMLTQGANPCENLQCGPGQECDIDRYGIATCQCPPSCEPVMRPVCGEDGVTYHSECDMRKSGCEVQKAITVQYRGACENRFLVPVYPFTFKCENGLTCRTNWSLKLGYGMVEDSSRVLSKLLEFSVKNIFTTRYALVKYEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SL77</accession>
    <name>A0AAV4SL77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_615781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009712">
        <property type="protein sequence ID" value="GIY33966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SL77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22281" checksum="53AD953DE589A1D5" modified="2024-11-27" version="1">MVWLASTRRSDKQSLESCCCKCYCPLYCDGPWLLPLTIPPPPLFISILPSSLYSFRVRVCVCFLLAHHFLRFVFGCGVGEAMKWEAVRRGYSDAVRFGLYVVFPPPPSVLPSLSAWRWQKWQLPILEATHGLEEKGTGEFRQSHADNWGTPFVFAVMVNRACVIDDTDLPLFRTKLGFRISLLFVTLICSSPSPDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SN83</accession>
    <name>A0AAV4SN83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_369421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009876">
        <property type="protein sequence ID" value="GIY35215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SN83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9488" checksum="24D7CDFB452C596A" modified="2024-11-27" version="1">MTSEGPAVMRYKAQSDYRIIPINQYVDVCSGNRHNKSASEELRLLGSKSRISSCQTSRLQNRFGIVVHIANQMTLSNNHQLHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SP03</accession>
    <name>A0AAV4SP03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS_1_like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_87917_1</name>
        <name evidence="8" type="ORF">CEXT_106341</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010017">
        <property type="protein sequence ID" value="GIY36173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SP03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY36173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19434" checksum="72CB82A8B012B2AD" modified="2024-11-27" version="1">MDVTSMSLVKQHDSDFGRERFFSISGILVVSPIAGYLVDATTTDNAEKNYLAAFYLFMATVLVILVIVYKLEVRINSPGKKMWKKTMFLMKNPDVLSFVLVIFILGTAFCFTKNFMFWYLEGMNSPSFLIGLIPAVSALYGLPFLVTSRWWVNKNWCHSYIPTGFARICY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SPI6</accession>
    <name>A0AAV4SPI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_754831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009760">
        <property type="protein sequence ID" value="GIY34385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SPI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19689" checksum="56A5DEB24ACB1F43" modified="2024-11-27" version="1">MKSASVADFGSIEGAVSGYIRHRRTLAAESNANLVWWRTCANYYNYAPVRPAHSRLSQTYARHCHIGWKSCLLMACVQLTVCFAKMFDDKEHRKATCCTSRDDHRFVTFPGITRDESDFSTQMFKHLLSSLEKILSEEMLKSSESDGRTQTQARLFGSSGNECLFSIDFMVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SS88</accession>
    <name>A0AAV4SS88_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_356931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009958">
        <property type="protein sequence ID" value="GIY35771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SS88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY35771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12214" checksum="203D64B7BCC9A161" modified="2024-11-27" version="1">MHPKLHQKLTHYPGTSLDMSSGRTKTSCVQHQFHTTFGSHQNRFKLETLICSNYHPEKPLKVGEELKLHCETSGSRPPAKISWWMDNIRIQSGKESIRIAETSRTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVB7</accession>
    <name>A0AAV4SVB7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tektin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TEKT4</name>
        <name evidence="6" type="ORF">CEXT_561051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Cytoskeleton</location>
            <location evidence="4">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tektin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010121">
        <property type="protein sequence ID" value="GIY37086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048256">
        <property type="entry name" value="Tektin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000435">
        <property type="entry name" value="Tektins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19960">
        <property type="entry name" value="TEKTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19960:SF12">
        <property type="entry name" value="TEKTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03148">
        <property type="entry name" value="Tektin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY37086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="317" mass="37326" checksum="E1B3A725551EAD55" modified="2024-11-27" version="1">MNTFTPQIFSTEEWYRNNQRRFNQSDISRAEWFRYLCQYVLVCIFGEQFTFHAIDIGWISPIGKQTRVHIQLYYASRVCQQSKQLAKEKKLLTETVQDDSTKKIAERAKQVFDCQKDLEKALEQLTTETRKLELRRNVYRTPLKRGAAEPDRGPGESGPQGSEGIEIEIVQTYRDLTKMIIAELENQIKRNQQSKNELERDWSDKWEAYNLDTISAHLQNTSSEQIAFYTGPQKIPNKWSSPQEWIEFTRHRLFYAKDEIRTSAILRDKINSHLQNGYKDLRNQADLVESVLAQRINEKNDSLYRLKQHLLLVSIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1J3</accession>
    <name>A0AAV4T1J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">cGMP-dependent protein kinase, isozyme 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Pkg21D</name>
        <name evidence="3" type="ORF">CEXT_525181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010538">
        <property type="protein sequence ID" value="GIY39964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="90"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY39964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="17995" checksum="D1E0965DAEE81E67" modified="2024-11-27" version="1" fragment="single">MKFFSQSVLEITSNNANPSTIVPNNVGAGDFSGSLKPNLAPPTTKKQGVSGESAAHPSAKGAPDYKMEKHEKDFRWKQLIKDAILTNDFLQHLVTSSQVKEIVDCMYSKNVPAGSLVIQEGEPGRHLYRRTGGEKGGNSVGDDGPWQSFRRACNPLQLHKNSDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4H1</accession>
    <name>A0AAV4T4H1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_274061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010480">
        <property type="protein sequence ID" value="GIY39567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4H1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="24167" checksum="00AC4A0B1E3E54E5" modified="2024-11-27" version="1">MLGRQCGYCAGGRAISDYNAPIYAMVKAEMGFTDFMGLLGVPPFPDAISLKFTTKDLNLNLDFVPVTQFVVCGETSSFQNSLNFPLQSLLSESKKLISLKFTIKNLNLNPDFVSVNHSVACCIPGSFRFPITVPAFRNKETAWESDSWERSTCTIARRTLTDESHAAPKTDTDRTLGRQSRHAKLLQAPWENLQGTSVCVISTMREKLCSCVGGAVILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TAI2</accession>
    <name>A0AAV4TAI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_636981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010947">
        <property type="protein sequence ID" value="GIY43204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TAI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11522" checksum="EE3050BE0CFF8F2F" modified="2024-11-27" version="1">MEQRGCSRKRRKKKKKKKGIERFCGEGRGWSSEEIGVICISGPAPMWVSGAGGEVVSPQGFWACLHSSVAGGRRKAFHCLSYSRRRKKKKKGINSNDVWKIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TE06</accession>
    <name>A0AAV4TE06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_436761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010998">
        <property type="protein sequence ID" value="GIY43612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TE06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18400" checksum="ED291A6195F2EAF5" modified="2024-11-27" version="1">MCSNAFHKIIQSILFTKIHPKNYSFSDNIGKIFPSSLPRKPRELYPSEEPEASEKPNRTEHRVRHKVQRTNNASPKKTTELYHSRELKASESQTGLSTECATKSKNKQHGEVDKDAVFILSSALSYLISPFFLAREESCAPYAMDYILFEYEITGHLCWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSP4</accession>
    <name>A0AAV4TSP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_19681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011524">
        <property type="protein sequence ID" value="GIY47118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12036" checksum="EB015BCB77D6C8B6" modified="2024-11-27" version="1">MDPLIVRQRIPMEEPVVSLCYVTSHDATLYGASCGMPKCSCDVKYPMVFLHGMDPLIVRQRIPMEDPVVSLCYVTSHDVTLVCFIPAFPDVVHPMICQNVLIVWSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYM8</accession>
    <name>A0AAV4TYM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_266071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011936">
        <property type="protein sequence ID" value="GIY50082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9552" checksum="558B261FC39D8FCF" modified="2024-11-27" version="1">MTIEAWQSKLLVPQSMENITPSKDSNFSPSARMLPSAHDSGLKETRNKMIRSHCAGIGCNISSVQRLFQLEEQEPGFTWSAPCISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4Q0</accession>
    <name>A0AAV4U4Q0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_414211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012280">
        <property type="protein sequence ID" value="GIY52720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4Q0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11364" checksum="929879C5C740780D" modified="2024-11-27" version="1">MVRSMNCVSEANARISQLEAALQQNLLKMQQMRQFLEAAQERHQHQLLIETQDANGLNTPQEQQQMTMEQHVQDIKARLFGSIAEGGIGSFVGQQQNQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U844</accession>
    <name>A0AAV4U844_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_239111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012431">
        <property type="protein sequence ID" value="GIY53928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U844"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10422" checksum="CAE300CB52978D5C" modified="2024-11-27" version="1">MVRLWFTEQCLRFCKPKALLNVNTGIETAAILCGGRHKRERSSVSLPGTRRSHVPFCSERMQEKAPRCFPRACLFFLSGRAYFVSPVFNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAS2</accession>
    <name>A0AAV4UAS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_763581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012561">
        <property type="protein sequence ID" value="GIY54878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10214" checksum="250AF26B014CA921" modified="2024-11-27" version="1">MRRMYARIIITTLGAFKNIVKCHVVNCKPIGSLIGQPIVLSLGRGLPLWGFKNKIKRIMDMCPHVGRRGQQTLIQLWTGNIQDNPSGGQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAU7</accession>
    <name>A0AAV4UAU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_763561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012561">
        <property type="protein sequence ID" value="GIY54876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8079" checksum="5268BEAFDB4BF3E9" modified="2024-11-27" version="1">MWASSNKYGTETRNVPLNNRKRSIIYTFHPVQDIAAQMTIAVSSVCRSDYGVLGLTLASVCLTIGKQLSPNSCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEY0</accession>
    <name>A0AAV4UEY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_31521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012748">
        <property type="protein sequence ID" value="GIY56239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11517" checksum="F3004AF181AF0D67" modified="2024-11-27" version="1">MVLYGQIFNFRKDSAFAHTETMSVPKTRTIQIDPCPKEGIAYGKRQGASHHQDECRVALQTITRRETLQKKQRKKKSFPLANNSRLPSSDNGFMRYDSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPG9</accession>
    <name>A0AAV4UPG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_152981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013221">
        <property type="protein sequence ID" value="GIY59615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11660" checksum="BF5C255A2B472A6E" modified="2024-11-27" version="1">MERAETIDYSVRASALGASNAELMDTTSASIPSELLASPIFHEKLSEEEHCARISTVTKKKDLAQNLYDAYAATLTGYSPDDDDLKELKIRHDNLQLAMREAKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTE4</accession>
    <name>A0AAV4UTE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytoskeleton-associated protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CKAP5</name>
        <name evidence="6" type="ORF">CEXT_454031</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013450">
        <property type="protein sequence ID" value="GIY61297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UTE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061863">
        <property type="term" value="F:microtubule plus end polymerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000050">
        <property type="entry name" value="Cytoskeleton-associated protein 5 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="135"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY61297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="623" mass="69662" checksum="F79A98C8296833F9" modified="2024-11-27" version="1">MLHVGYEPMARAASKLKPASKATVVAQLEKVRQNLPAKPTTAKTKPTRGIAPPSERSSPPQTVPNEEGGKGKLNRSTSKSKLALKATSSSTSKNKKEEEIDTSPSLVANNMKDQRMSDEKALKVLKWNFTNPREEFYIQLKEQMTAANWSKTLISHCFHNDFKFHIKAIDLLIESLSNSIEASAANLDLILKWLALRFFDTNPSVLIKSLEYLQVLFQALMSINYHMLEPEAASFVPYLILKIGDPKDTVRKGVREIIKSISRVYPYSKMFSYIMQGLTSKNARQRAECLEELGSMIESYGLNVCQPSPAVALKEIAKQISDRDNSVRNAALNCVVQAYFIEGEKVYKFVGQLSDKDLSLLEERIKRSSKPKAKPVESNIPPAKVSPPVHLNSSYATPVEEPKASLTATPVQRSGHLRLETDDIEQMFRHREPQVQLPGLIQVNADDILNLPDIQLPRTRMRPPATSLKILNSADDVDTAVNLVMAQLAAQDIPVVIQAFAQIEEVLKSDQAVRVLNSRVDQLLVFGGLQYRYAHNKHMADENICKADVVSLYRCVTVALASLFDDAVLSKKASRDVLRDLIPHLITVMLDNRLDDLQDGAQVVKVINVLIMRILQKPTQLMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5X9</accession>
    <name>A0AAV4V5X9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_128671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013992">
        <property type="protein sequence ID" value="GIY65453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21121" checksum="07C5A16FC55E099D" modified="2024-11-27" version="1">MQQTDCFHGPASNISQRPLTPIKTATWPKLANQSVIPEPVRKAFFCPPDGARGSIKRCGFPETSRTIVQSISVSNSRADLEKSPVVAKKKKKKELVVCEKPHPECLQGMTSLWMTDRRPAFSEKPISLSVCSRQKRFLTAAAPSCVQRQQEKRKKKIPCNAMMIVYFRFAYLEIQSFSVDCEREDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6E7</accession>
    <name>A0AAV4V6E7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_300301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014001">
        <property type="protein sequence ID" value="GIY65521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6E7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7364" checksum="78B59313E0AE129C" modified="2024-11-27" version="1">MRINGFDSRAPGSGPLTSPLGKEREEERGGSDTRFSEAPPTRLGCDDPKKFCTPVQIKHKEESGFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7U3</accession>
    <name>A0AAV4V7U3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014010">
        <property type="protein sequence ID" value="GIY65610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7U3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12227" checksum="42353CB2B1C2A9F3" modified="2024-11-27" version="1">MRMSSGMDILLSEQTKTITSSGCTRQPPPPCHGAWKFRRKEYRREEEEDEFGVVVVRASMHITQERRCRPIDGVIYFDNEEGLEAHLHTEVSSETSFVNAEKALRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7Y4</accession>
    <name>A0AAV4V7Y4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_440471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014027">
        <property type="protein sequence ID" value="GIY65794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7Y4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="8549" checksum="26C9FC7128A4F38A" modified="2024-11-27" version="1">MLSIFRCAAISDGRDSAGGAAIAGAAPVRGRGGESIVERASKELVTERILAELEATWAEIAFEHSLHQRTGYRCSTSPNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBM0</accession>
    <name>A0AAV4VBM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_526911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014252">
        <property type="protein sequence ID" value="GIY67526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="210" mass="23494" checksum="1F6D9A92D2D815CC" modified="2024-11-27" version="1">MGQSSIAVARPAWVHAVRAGFFWSLGWGCCGSANHQLRNVLILAAKHHRLSGRKDCTAGRQNHRTRKVPKINIPEKPATYATMAKNMAKSGKPQDRQRSRSRPNITKKFVTTIKPMDITPDNTSLKTKRTVQAKIDVKKINVAIKSVKPIKNGGIIVETISPEEDLDKLIYEFKAKDELTKEYQIGKPGTSTLFALTCLQTQKKKFSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGV2</accession>
    <name>A0AAV4VGV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_178211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014440">
        <property type="protein sequence ID" value="GIY68778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12364" checksum="9F54CB1F00E1E222" modified="2024-11-27" version="1">MVMLKAQRKRRSGTAPLRLGNFHAKRKKGRKGRKSKKFLVHVTPNGINTQEMRFSFNTILHPIFPETGNGDVFKRETYHLTNGDVWRPKEDTVSIEAIHSQFERLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKE4</accession>
    <name>A0AAV4VKE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine proteinase stubble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Sb</name>
        <name evidence="6" type="ORF">CEXT_218831</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014723">
        <property type="protein sequence ID" value="GIY70807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000006">
        <property type="entry name" value="Serine proteinase stubble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="166"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY70807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="409" mass="44618" checksum="C3AE0DDDEC295515" modified="2024-11-27" version="1">MAYAIKIRPESCTNAMGDKGTCMFVWQCIKQDGVQIGTCVDRFLVGACCALPKEEENFVPGSSSLDSASILKKNATSTSPPPPKVKPPVPTFVTKRPELMTTRPLIIGTNSRPTEVPSPITISKPFASSLMAQATTAQLMVKTTKKPAVDDFTECGIPAPFPKSKVVGGTHSSFGEWPWQVSVRRSSFFGFASTHRCGGAILSASWIATAAHCVDDLLKSQIRIRVGEYDFSTVQEPAPFQERGVEKKVVHPRYNFFTYEHDLALVKLDAPLQLQAHVRPICLPARDETFVGRNATVTGWGRLSEGGSLPTKLQQVQVPIISNEKCQKMFQTAGRQENIPDIFLCAGYESGGRDSCQGDSGGPLQAKREDGRWFLAGIISWGIGCAEPNMPGVCTRISKFTSWIKQNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMN8</accession>
    <name>A0AAV4VMN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_643561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014783">
        <property type="protein sequence ID" value="GIY71308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="6995" checksum="3051A29C0CFFA0F6" modified="2024-11-27" version="1">MHATFAVTIATKEWGRVRLQHLPVKGLSEREHAAQGPVPARDTERTTDGAVLDAGVPGLQVAGLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VN39</accession>
    <name>A0AAV4VN39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_417511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014832">
        <property type="protein sequence ID" value="GIY71606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VN39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13856" checksum="AD4D1EB136A86118" modified="2024-11-27" version="1">MSAYQPQCALGAGGLRPDPEVPWLPVAWNHLWSRFTRCRAPGQPHSVRGLSQQCPILRHQNNDVAFSDCTGQSLQLSVLSEMAAVSTQSVLNDRKRILWDSKHSDCVAEIFTELSCTATSCQSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VP50</accession>
    <name>A0AAV4VP50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_787501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014868">
        <property type="protein sequence ID" value="GIY71918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VP50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13007" checksum="6A11E05F63543E0F" modified="2024-11-27" version="1">MEKGCHIYLFVTFSTSEFWQCVRRSAKADEDLKSGRSRDTRVLRRKDGVSRRSRSGKPGSFPGWRRGPKVKKTGEIQRDTESKAISHHEHRRDVRTTMESGEESAKAKANLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPQ9</accession>
    <name>A0AAV4VPQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Intraflagellar transport protein 22 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ift22</name>
        <name evidence="1" type="ORF">CEXT_474511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014896">
        <property type="protein sequence ID" value="GIY72098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="271" mass="30818" checksum="0FF6B8DC9120D4D5" modified="2024-11-27" version="1">MYKVKLLVIGPCECGKSVISNFLADATETISNEYYPTQGVRILEFESDNLNIGGRIAKTEVELWDCSGDTKYFFFPSFFYFCDSYIVCVWFENCWPALMKDGNGVIFVYSSDFVNIRKEMDMWYANFVQAQGLKDSQCMVICHRKPNQPETRSSELYPHASVSLCVFLQPAFFPRALGVRGGGRRGRSKEGIQQLPAEVAERHQRAQGPGRAEHPQPALSTRLLSIWDYVIGVSTPVTEGYRKEEQSASILPIFYSSEATQCQWNWPSMQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0F3</accession>
    <name>A0AAV4W0F3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_494071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015304">
        <property type="protein sequence ID" value="GIY75153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0F3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9658" checksum="7A4AA5B43FC8E59F" modified="2024-11-27" version="1">MFLSQYHKSERISSLHTPTLLTCYPFRILEEVLSPPPNFIFPNHSHSMGQNSRKLTIKQQHANNSPPRKIHLQSSLSHNIEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDE4</accession>
    <name>A0AAV4WDE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_179701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015950">
        <property type="protein sequence ID" value="GIY79981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14025" checksum="FFEE478B25AD033F" modified="2024-11-27" version="1">MDKIFRLGTSHLCPFIQIWQRIIHFVDEICLPRISLKLDFVQVLCQRKVIQKSKRLLLSDAISFWTLCLTSGKKNSRMLLSITGDGDAIVSVKVRLHCTKVRLDKSPLFEWCGSGSPDSADDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WS40</accession>
    <name>A0AAV4WS40_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_657181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016567">
        <property type="protein sequence ID" value="GIY84766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WS40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9959" checksum="F06D93E021815993" modified="2024-11-27" version="1">MRKHSRLGSSLEKFNRELLEVIYFAVGLKTKEEQGKGKVKTENWSYGIDLKGKVWKIINGAKKKAFTPVSYKGTRKWIKRLCGRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWC4</accession>
    <name>A0AAV4WWC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA-binding protein squid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">sqd</name>
        <name evidence="11" type="ORF">CEXT_701301</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016908">
        <property type="protein sequence ID" value="GIY87202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12325">
        <property type="entry name" value="RRM1_hnRNPA_hnRNPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000030">
        <property type="entry name" value="Heterogeneous nuclear ribonucleoprotein d0 isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033">
        <property type="entry name" value="RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033:SF10">
        <property type="entry name" value="RNA-BINDING PROTEIN SQUID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="60"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="142"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="215"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="320"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY87202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="352" mass="38186" checksum="9D140B6DA191D1DE" modified="2024-11-27" version="1">MATDGQQFENFAEDQQYSEYNEQSYTEAMEEGGDSADQMQNLNGTTNGQSANKTSSDDDRKLFIGGISWDTDQKDLKEYFSKFGEVTDVTIKTDPATGKSRGFGFVTFAVEETVDNVLKAVPHTIKGKQIDPKRAKARPGIKKIFVGGLDNDFPEADIRAYFEKYGKIENIELPFDKVKNQRRQFCFVTFEAEEACEASCKQAKQKIGNKECDVKKATNKPDPRLGGRGGPGGAWAGGFAGRGGRGRGARGRGGPGFSQPQSWSAPGSYTSSYGGQGYGYNQNYNSGYGNYGGYDYTYGSGYGSGYGNYDYSGYYNQGGGYGGQQPSSYGKTPRRGGAATGAATTAYHPYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWT1</accession>
    <name>A0AAV4WWT1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CXXC-type zinc finger protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CXXC1</name>
        <name evidence="13" type="ORF">CEXT_362401</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016769">
        <property type="protein sequence ID" value="GIY86264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022056">
        <property type="entry name" value="CpG-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12269">
        <property type="entry name" value="CpG_bind_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CpG binding protein C-terminal" evidence="12">
        <location>
            <begin position="238"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="270"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY86264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="315" mass="36437" checksum="4A34499C5A60F536" modified="2024-11-27" version="1">MQKKRRLQNEVSERKNVSSKAIKKHDASESCTKNKEASFIRLGDRHGQTMDDAELASIFQMDTTRRKAKLIANKNLKQCQNEHYEEIPQEKIKPKEEKYSNLQQCYGPECINAARENSKYCSDECGIRLGRNRILEILPNRIEQRKIIPCAADEASRHKLAVLVLRLKNSREDMIVEDDSDEENIIVDCKLCGGEFSIRVIVKHMEKNGSPRAMQATSSPVSFPYQGIQRRKRTMWLPNQSEPVARRGKFCGRTNKSCTSHPSSWESIFRAELDLEKFKLLMRLAELEKEEKQLRNEMANRGNLMALLLHHTIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD39</accession>
    <name>A0AAV4XD39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_203091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017467">
        <property type="protein sequence ID" value="GIY91889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11420" checksum="FE695BBC2B4D27EE" modified="2024-11-27" version="1">MGAGLCAGTRMTDPLGAPMECIEGGYHPGNGCLHLGQQRRRQAVGYCSSARISNSGHRVHGGHVLMLMSPMTLLICPIFVSFRYGRWYDTVPLFSHLPIVWRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFL0</accession>
    <name>A0AAV4XFL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_208531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017710">
        <property type="protein sequence ID" value="GIY93820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10453" checksum="565E5447D83D78B7" modified="2024-11-27" version="1">MIGHETFCAQTRPFSSRLCQYTEVQNMVIGKSICKCTSTASFWKDNCVVWVDGVVYCKTIVFRGGVSRYFTVNGKHSLLSKPGHSNTSTACMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGV6</accession>
    <name>A0AAV4XGV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_174781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000220">
        <property type="protein sequence ID" value="GIY93018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="14182" checksum="E4156151D9CBB5D5" modified="2024-11-27" version="1">MPPTLHLTKRKGNFSKRLSLDFHIYAHWEPHTLRNNKQARRCATIIPESIRFSPKRNDCSPRHHQESNPRPFRKLRAETLKSQVNFLVSTSRFIYPTQSRYRNHQTCADWLKGVDENKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHH0</accession>
    <name>A0AAV4XHH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein F54H12.2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">F54H12.2_56</name>
        <name evidence="1" type="ORF">CEXT_200841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000261">
        <property type="protein sequence ID" value="GIY93390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="379" mass="42093" checksum="9E76780D16DD40AE" modified="2024-11-27" version="1">MKVPYVCCSKKFEEHYTNQSGSGIPHYEGISFQRGYGLGGVFRRLFRAALPFLVRGGKVVGKEALVTGTKVINDVLSGKDLETAAKSRRSPECVKSELELFHLPATQTAIEDGHWVEFHPLSNVFDGGPVEFHISGSGEEYVDLSQTQLYVKAKIVKADGKPLEKDEKKLVLKVRVSPGVILGHAKALENGTAKYPLNRVLCKVYSVPQGSMSFVQDNIFVGQMPKRIIVGCVDNDAFHDESSEPGSHWLAFYCENGCIEFFDSFGNPPDFYDPRFHEITLRYPSVCWNSTPLQNLTSNHAAWTDQSDPDFCACTVFAIDETAAVRRKEPNIHGAFLQKQVSDSIITLMSDILGWQAKTPSDLSSFVYHYSSSLNAVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJA0</accession>
    <name>A0AAV4XJA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_17691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017766">
        <property type="protein sequence ID" value="GIY94295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8672" checksum="18752FD2AEF4B0AF" modified="2024-11-27" version="1">MQLIPLSPLEQRPHKKGGLDLGWRNDICPLLAHGSQADGQHHLPPSTSTHIPLQKSCWGVEGRKFLPVGNRFFHQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL92</accession>
    <name>A0AAV4XL92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RPA_interact_C domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_1991_1</name>
        <name evidence="5" type="ORF">CEXT_91001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017855">
        <property type="protein sequence ID" value="GIY94985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028156">
        <property type="entry name" value="RIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028159">
        <property type="entry name" value="RPA_interact_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31742:SF1">
        <property type="entry name" value="RPA-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31742">
        <property type="entry name" value="RPA-INTERACTING PROTEIN RPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14768">
        <property type="entry name" value="RPA_interact_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RPA-interacting protein C-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY94985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9261" checksum="EA66217FB81F1950" modified="2024-11-27" version="1">MPTLSKNPLHQIHTVIFCACGVRIDVQNDGLTLQHLKSELHKGLKCHEQICHVTPSFSLLHFMDNTNLAIICGDCNFMYIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR80</accession>
    <name>A0AAV4XR80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_420101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018198">
        <property type="protein sequence ID" value="GIY97686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10272" checksum="B141990154E96383" modified="2024-11-27" version="1">MIKLLSNYKEVGLSSTYCVGRPVSLNVFKSLGGALLYINAREVSREVIDDCDDHLPEFTIKEYENIVNLLDIQPALRISTPLNLSELFGGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUP3</accession>
    <name>A0AAV4XUP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G_PROTEIN_RECEP_F1_2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_114751_1</name>
        <name evidence="2" type="ORF">CEXT_633961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000982">
        <property type="protein sequence ID" value="GIY98886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8008" checksum="CA5C018195B06EFE" modified="2024-11-27" version="1">MKSSQGTPQPMWKGSKITKEGTQNSTSNGSQKDCIILEQMNKMNPKLRIIFNTGTHKKPAGSQPSSVKEESSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XV52</accession>
    <name>A0AAV4XV52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_141561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000995">
        <property type="protein sequence ID" value="GIY99036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XV52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14302" checksum="A809EC7DC2D9DB73" modified="2024-11-27" version="1">MIVPSHALCINLFFWSSSTQSGFECPFHFDSSLSRPSLKTKAVLIHGKRTFPCMFSMVGLVLLLCTMTQSIKFSSNAIEMTFIFPAVVKRSRNLIAPSPVPALWGEECSLLPSSLSGDNGHESLGLSAQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWW8</accession>
    <name>A0AAV4XWW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_703061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000999">
        <property type="protein sequence ID" value="GIY99058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12937" checksum="CADC84AD58182BA3" modified="2024-11-27" version="1">MAKGCAIRASREIKGLIVQVANPLKGGLPSIKRMNHALTQFRFPTLNNGHGETVLYPVTKRVGSECSSSWEHLKNFRFCHKTMSSFAHNFLPVKVRFFPSSGEISMLISCDKWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWX5</accession>
    <name>A0AAV4XWX5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_645471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000926">
        <property type="protein sequence ID" value="GIY98431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12754" checksum="79B7A2C41968B8B7" modified="2024-11-27" version="1">MRNIQIFVNLPSVRRLAPFGVRSDSLVTPYHPAESEWEAVFEVSRYKQKQEKEYKLIIGTPFFRSLAHNTNRKCTSHVDTLSQGCFLLKKGALESPLIPQEGTAAPHELLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY23</accession>
    <name>A0AAV4XY23_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Inversin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_99921</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000956">
        <property type="protein sequence ID" value="GIY98730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="11" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="234"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="301"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="334"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="400"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY98730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="54405" checksum="DFFF31EE32F6421D" modified="2024-11-27" version="1">MTLPLHVACSTGNRNSVKKIIDTVPLHLLETKDETGKTPLMLCVMHNQVECANFLLKAGVHVDNCDHAGQTALHIASNKGFHRCIRLLLSYNASNIKPGAIDIQDSSKKTSLHWSTAYANIENTKILLAKDANICIPDEEGKTPLHWAATNASVHALECVKILLEKERSLINWQDYSGRSAVHLAVATGSIEVVRYLVCREDCSIDILDNTFCFCGKADILLSGRACYTSADDNGATALHYAAFNNHAKTVEVFLSRNYVSVDVEDSQGQNALIWAAAQNSKDVVNIMATNGVNLLHADKNGTTALHAAALQGHEATTEMLLNLLVPIDVKDKCGMTPLLRACEFGRSKTALLLMNQGANIYEKDAKDRSSLHWCALGGHAYLCQLLILKKVECDDQDVFGMTPLHYACMKNGYLNCVSVLLESKAQVNLVDMEGKTPLHHAILSDHKGAIKLICDYDGDVNAMVLLQNNWYKSIYLENYLRFGRYEGQYRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYA5</accession>
    <name>A0AAV4XYA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_123241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000966">
        <property type="protein sequence ID" value="GIY98793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8537" checksum="1DE698595BA2B50E" modified="2024-11-27" version="1">MLSGIQGGKRELRGIVSWRGLGDRGGWKNWVPLGTPERSCSQLEDWSRRGRKIYGCVKILLKYVKHGVILDISIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y003</accession>
    <name>A0AAV4Y003_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_55735_1</name>
        <name evidence="3" type="ORF">CEXT_72061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001049">
        <property type="protein sequence ID" value="GIY99468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y003"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051568">
        <property type="entry name" value="LZTR1/Attractin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376:SF1">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY99468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="233" mass="26602" checksum="0575A7E6BD36E711" modified="2024-11-27" version="1">MDYPFLISVQSVWEEMKCRGNRPPCLQEHSMVCWKNNIYVFGGEIGFASTGETPLWILDISCSVWRKHHVRGSSVHQPSGRRGHSAVMFDGFMHIFGGYQDLRGSSSELWIFDLEQSIMQILGLLGKLISVMLNSLLSSMYFLLRSFSEKFFSKVKEKAPWEECGLPSEGENESHLIDRAMQAEHPIRFKPIPLRCLFFAHRHPQHPLGSLSFMRISQDSSFDSLHPGDSPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y195</accession>
    <name>A0AAV4Y195_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_87531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018635">
        <property type="protein sequence ID" value="GIZ01153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y195"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8129" checksum="F9412788E1C22428" modified="2024-11-27" version="1">MESFRFSTGSSPPSTKLIETEEEKKHHGLSQCHYFDAKITPECTMLGKKIKDNQVTELVMVIVVGKCKRDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1K5</accession>
    <name>A0AAV4Y1K5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_727001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018656">
        <property type="protein sequence ID" value="GIZ01336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="23594" checksum="670F6F7E9E5192CF" modified="2024-11-27" version="1">MSWVLGLLLETVANRAALESQKITALVNFSRCHCSWDRTVRIAAPSNALPRSTGAFIKSPKADCQITSLILEMGNIVSKFDKLSKIKLSMYPYLIINGGAIKQTQCCPSPRNLTEWFQIGKTSTNLSPDSFSLLEDSSLFPPFISGSFHQDWPLWREIMLGNHKSGEGKLGHSSHWTSPRAMKISGSSSPPNNPIRLMAYPLVRKRGWFVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2R0</accession>
    <name>A0AAV4Y2R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_487981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018668">
        <property type="protein sequence ID" value="GIZ01443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11291" checksum="947E5A865E57EF9B" modified="2024-11-27" version="1">MDNLQLGNEIDLPIPPEIGVSSTDSLSFECNPEAVDICLHIPSGVTFHCLSGFAWHPLHSTARWSVPLGGNLHIVHHSEVDKTQTEKHVCSHLQPKRESLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4Q8</accession>
    <name>A0AAV4Y4Q8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_171371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018733">
        <property type="protein sequence ID" value="GIZ01879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4Q8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14478" checksum="767367392BC1A918" modified="2024-11-27" version="1">MRKVWLHDDYSCCISAQKWIFSRLLHCDSLPSRVAHRRHAMSFFLRKWIFLHTLIAHFPFFGHLFNQFKHPGWFCVRGGPHNFSITVWQHCSAQRQWTAVVQLGNRPDSEEGNFRHPTEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4U9</accession>
    <name>A0AAV4Y4U9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_148991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018737">
        <property type="protein sequence ID" value="GIZ01924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4U9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9840" checksum="F63675C0A9242FE0" modified="2024-11-27" version="1">MPTHTLLALISPDHSTTGRREKKNQTKKGGHVTERLRTGSRFGLQLEPSTNYAGVQHTGYYSRKLNVVDAQHQHGSFKTEFLVGQPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5M5</accession>
    <name>A0AAV4Y5M5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nudix hydrolase 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NUDT8</name>
        <name evidence="5" type="ORF">CEXT_445811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001407">
        <property type="protein sequence ID" value="GIZ02179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5M5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04670">
        <property type="entry name" value="NUDIX_ASFGF2_Nudt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000015">
        <property type="entry name" value="Nudix hydrolase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003293">
        <property type="entry name" value="Nudix_hydrolase6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040618">
        <property type="entry name" value="Pre-Nudix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13994:SF13">
        <property type="entry name" value="FI03680P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13994">
        <property type="entry name" value="NUDIX HYDROLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18290">
        <property type="entry name" value="Nudix_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01356">
        <property type="entry name" value="GFGPROTEIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="104"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ02179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="266" mass="30824" checksum="3E843C292B074AA3" modified="2024-11-27" version="1">MTSKPIELYNSFEAKLDIYQGLTIEAQNLSFSDNDFENNLKTSLPDWIKSGIRGVWFKVNIANSSYIPILVKHGFLFHHAKTSYVMLTRWLPSDEPNLLPQYPFTHIGVGGMVINDKNQVLTIQEKYQQRAHWKLPGGYSNPGEDFSDTARREVLEETGIETEFMSVVAFRHHHKHIFNCSDIYLVCHLKPVNDIIAKSNEEISKCEWMEIEAYRNHPEVTEFNKFIMNAFLESQQLKSSIIASPILSFRKDCYNQVYHVSNIEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6J2</accession>
    <name>A0AAV4Y6J2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_144511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018837">
        <property type="protein sequence ID" value="GIZ02640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6J2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="17962" checksum="FC29ACD92EBE558C" modified="2024-11-27" version="1">MERFRTYKTIPRAHPHAEFRTGTTTLGPDSCLTSIWSTDYEKVLSAFPICGYEVHLEANAISGGALLPLAANERHKQALRLEGKRKMCVSRIYFVAWFLLPTASFFREAFEGQVSSCCLGFTASSISSVPGELRLTIGVAVASHWGVGGGAHDAWTQVVCAHLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6V5</accession>
    <name>A0AAV4Y6V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_732231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001364">
        <property type="protein sequence ID" value="GIZ01884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10445" checksum="1F8440479D3477A5" modified="2024-11-27" version="1">MQETETVYRERGESVYLEGEHIDVQTLRMARCVLTLCRRTVTRLLCEKSCGRCCSEAPPHRAGADGATAEQQLLQICSCRRKSSDISFIKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBC4</accession>
    <name>A0AAV4YBC4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_622261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001765">
        <property type="protein sequence ID" value="GIZ04618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="15964" checksum="DF1B3828FB444FEA" modified="2024-11-27" version="1">MLCCVDFSLGGAMKRFKTSCYAGLLGDLKLPSRLICNYFVTFWKYADILYNRLIRFPNNSGETTTVLNVKTDFGLKGAGILNISSRYLSLHSAKLEIKNILTKLFRSGTSQDAGDKSSCLLYGHTVSRINLCCCCSHVLSLDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBE7</accession>
    <name>A0AAV4YBE7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_566051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001757">
        <property type="protein sequence ID" value="GIZ04557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17696" checksum="FF0C62BBC990A817" modified="2024-11-27" version="1">MIIYTEYCICCISNRYAVPFLLCFFLQQCREECLLNVSLKEAGCVDPIYIYYPNEAKMCDHPAMSNFYYKQCRFLQPSLQVTEKNIRVAVEEYASLLSLRDKDGVEQCSSVITLAFNRMELKSSLIILNMRVSIYLESLVDTWACGSVSLCWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDW8</accession>
    <name>A0AAV4YDW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_473731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019083">
        <property type="protein sequence ID" value="GIZ04419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9462" checksum="BAF089C2A326F563" modified="2024-11-27" version="1">MLTFCKTLWQKLRMSRSLHMSWTSSKTSFRSSGVCNSLESVPAEQLLLEGGRTSPWGGCDKRGPVGCHRRSYLGWACKSEEAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M812</accession>
    <name>A0AAV4M812_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_574191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019466">
        <property type="protein sequence ID" value="GIX68179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M812"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9003" checksum="B9C23ACB518B03DB" modified="2024-11-27" version="1">MCAICAPMGRKRAQGARPLSSGHKFPGPGQISPQLTRLFVMRSTISSRSDSPIQCHAFRTVTLTAEERRSGKGSSSGNVKASSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M970</accession>
    <name>A0AAV4M970_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_664861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002008">
        <property type="protein sequence ID" value="GIX68941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M970"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8385" checksum="FF11F3FB560EF8A9" modified="2024-11-27" version="1">MHKLGNSHLGHFVADNIVCNAQVQLDHNEAVTELFENDSSFAVYSTNVENLTFPSRALVHSPTQSAYADGHGLLCNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFM8</accession>
    <name>A0AAV4MFM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_518371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019729">
        <property type="protein sequence ID" value="GIX71153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7308" checksum="8832AA7945C6A44C" modified="2024-11-27" version="1">MDGPFRGLSPEQIGFGEQLREIEINPCKCPGGTFLRSSSFEVSDGDFGAKGGIVFHFELSELDWVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNL9</accession>
    <name>A0AAV4MNL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_736201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020011">
        <property type="protein sequence ID" value="GIX73963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10566" checksum="7A161917E5D92D27" modified="2024-11-27" version="1">MHALGRSIRTFYGRSLTKIEGKNTRDVAAKKCDQSVSMTGIPQRHARGQVAQFIIDAITSDSTRAHRIAKIPVHPRGMMNRENGLKRTQSPHSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNP2</accession>
    <name>A0AAV4MNP2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box/LRR-repeat protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_77162_2</name>
        <name evidence="1" type="ORF">CEXT_546061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002435">
        <property type="protein sequence ID" value="GIX73626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="57662" checksum="FBC50E48D2B1A3DA" modified="2024-11-27" version="1" fragment="single">LEDTMPISPDSLYELCIEEIANCLQMKYWSGRKTNPFSRINCNIVNDLFQYLIIQAQVKDPRPLKSLLKSGQLQKLNFNGIDFTGKMWRYIMKILLKEKDRCRNITYIFLPKNFQNDENTYLERLIEQCPLLKEIHVGTYFNLSVLKNCERLKVVRNYFPGTHEYRFLRDESVDTLENLQNLEKFAIFDHRKSSTYYEDIAKILQNHPKLVSLGNTDSSWAAHHIHTTCRMDTAPRFGLKECFWGFAKNVEQFIRNQMAYSRQYPELIKSSVVLFPLVKRLHIIVHHADCLQHLKKLEHLCELEIDFNWCCSSSACTAFISLLSEIGPQLKRLVIVSHSTMPVDLVMKYCSNLEHLNLCCSAIVQGGVETNSNNFRELKELVVYEMDEESLEYLLRNSFNLKGLLLVDALCLDDTLLRTILLMKSLSKIETLGVYECRISRYLMKKLVQKCVKLRSAAFDNQDADLTAVAKQLKRDIRTTYSHVANRLQLIPEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N153</accession>
    <name>A0AAV4N153_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_133531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020422">
        <property type="protein sequence ID" value="GIX78532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N153"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12440" checksum="CBDD8646EC878560" modified="2024-11-27" version="1">MRKQHFHFMELKKNSASYLIKWLPWNHKSRSLTRSFRKRKRLVRSICSGIYTSRTELSDYGINEMLQNGQLVLSGLMRLGGFRRFNHGRYVLGVSAVGVRKVQPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5M5</accession>
    <name>A0AAV4N5M5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_424011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020530">
        <property type="protein sequence ID" value="GIX79756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5M5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19146" checksum="D77001585A7450E0" modified="2024-11-27" version="1">MGKKSEQWLPVSAKRLVLQLNRGVWGRGIVHQRRFVFRGAPWLRSSHIVWQLRGGPSTHPPLIIYHIAPESPALTNSDLTDQTEADQTKNTPAPLLNDTSDEYILVNQVLLRKASHYKTRLTQTATKIAKLKIDDPATSQLHTEMADLYKLTDGIKYEFGMSLFKYHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAQ0</accession>
    <name>A0AAV4NAQ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_97851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020726">
        <property type="protein sequence ID" value="GIX81909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAQ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10657" checksum="96D48373D35E3999" modified="2024-11-27" version="1">MSGEAIKSRQRQLFQERNNPRCNPSSIRNFAWNPVISPPLPSPGKAPERVRAPQTSAAIFLRMLFLFGFGTVVIFDSVGQKCIDETCCCGTLVRCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NB24</accession>
    <name>A0AAV4NB24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_153461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003139">
        <property type="protein sequence ID" value="GIX81544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NB24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12288" checksum="B8EF72F3BDC1D974" modified="2024-11-27" version="1">MYEFPTARVPFLELSCTRARAIKKHTSKRVRVETFIFPIRVRKRNFPTAERKSSIIHVRISCRPCTVPRAVLQEGLGDKEAHKQNRLGLRLLYSQFEYGNVTSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBX6</accession>
    <name>A0AAV4NBX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_540571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003131">
        <property type="protein sequence ID" value="GIX81456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="22997" checksum="50F6E72486639C7D" modified="2024-11-27" version="1">MFGRVTGKSDGYRQDVARESVVLTYPFIHCRIEPSCLSTVSRAKRARVINILARGTSSTNTINFAAEHQFILNPNLIEESLVPGLVEQAGPSTPEAAFLARDLLSFGQKITSDVQVIRRELQGDRYLFSHVRQTGISATGADAHYAFRMEMFESYSEHQFILNPNLIEESLVPGLAEQAGPYDPRGYVPRARFAFLARRLQATYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NC91</accession>
    <name>A0AAV4NC91_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">glutamate synthase (ferredoxin)</fullName>
            <ecNumber evidence="15">1.4.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">gltB</name>
        <name evidence="17" type="ORF">CEXT_97201</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (ferredoxin route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="15"/>
    <dbReference type="EMBL" id="BPLR01020729">
        <property type="protein sequence ID" value="GIX81945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NC91"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016041">
        <property type="term" value="F:glutamate synthase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050711">
        <property type="entry name" value="ET-N_metabolism_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938">
        <property type="entry name" value="FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938:SF133">
        <property type="entry name" value="GLUTAMATE SYNTHASE (NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="16">
        <location>
            <begin position="96"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIX81945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="28103" checksum="84A872C1B1846FBE" modified="2024-11-27" version="1" fragment="single">MYLGRLLEKQFRQADLANHFSVPFRIPDCEQRKLFSLLSCVQHIGILVQQPLFGRSRSPHLRITNPKMVGQAPSIEYHGLPPPRGLYHPQYEKEACGVGFIVNINGKASHKLIADAATISTRMEHRGACACDNSTGDGAGVTAAIPHSFYAQVLNTAMFSSYFHFQNLGRTGRHPSKSQYATGIVFMDKHTSSQAEAQFTQLAKELHLEVLCWRNVPVDSSILGYVAKANEPLMRQVFIAAPTMDSDTFRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NP12</accession>
    <name>A0AAV4NP12_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_79161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021141">
        <property type="protein sequence ID" value="GIX86428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NP12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14484" checksum="380C1359741BF141" modified="2024-11-27" version="1">MHMKNHCTYNRRAVPTLFCSPIKKSVFNREREKQWMTQPIIITIKWFTSTMRNKTRPFIYEKSALAAVIHKLQSEHCKASKILFGHRGASIVPRTSLAGAKILFGKRCSPPPCQAFGFVDVKGTAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRJ7</accession>
    <name>A0AAV4NRJ7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MADF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_239301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021148">
        <property type="protein sequence ID" value="GIX86526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006578">
        <property type="entry name" value="MADF-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039353">
        <property type="entry name" value="TF_Adf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12243:SF67">
        <property type="entry name" value="COREPRESSOR OF PANGOLIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12243">
        <property type="entry name" value="MADF DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10545">
        <property type="entry name" value="MADF_DNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00595">
        <property type="entry name" value="MADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51029">
        <property type="entry name" value="MADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MADF" evidence="1">
        <location>
            <begin position="8"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19326" checksum="4A61A01B1ADEBE22" modified="2024-11-27" version="1">MSISFDEILINEVQKYPHLYDLSDANHKNKFMRENAWQQIGFAMERNADNCKERFKYLRDKYRKEKYFMNLPSGSHRRIKKPWALYSAMSFLDPCHQTKSSCSNLLSQDEKDVQQESVTDHWLKLCTFLLSPFGERVSLKPGGQYLLFKGGMTSSASFKNYASIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWP6</accession>
    <name>A0AAV4NWP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_594651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021396">
        <property type="protein sequence ID" value="GIX89158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="349" mass="37484" checksum="DB30493EA55A2F5D" modified="2024-11-27" version="1">MAPVTHDAVFRDITLMKAIQRKVIESPCCWIMNRLRKVLYLADEEGFRTIIRTNEPGTKSSNPAGVDMEYSLEIRRQFQNIAQESIASLFSSVFGSSSQGPLVNPFSGPTGITSPSGSDLPSERPQNPPVINGKGPVFTAPKNAAAHSPHFNPGFRPGATYSQECCRILHILTQVFDQVQPILKVNSPSLNQLPGFLSPKGSNSLPGSDYPPQRPPVINGSNSLPDSDYPPQRPPVINGKGPVFTATKNAAAHSPHFNPGFRPGATYSQGQFPSLNQLPGFLSPKGSNSLPGSDYPPQRPPVINGKGPVFTAPKNAAAHSPILTQVFDQVQPILKVNSPSKSIAWLPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYD1</accession>
    <name>A0AAV4NYD1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_468691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021452">
        <property type="protein sequence ID" value="GIX89814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="31446" checksum="FADA09D8EE4346D2" modified="2024-11-27" version="1">MEDYLKLVHMELIPENEIDVPANSSFYLPHHPVPNKSGDKFRVVFDGSAKSSTGVSLNDKLMVGPQLQADLTTILIRFRMHKIAKTADIEKMYRQIRLKDSNFQRIVWRDSPFKPIQDFRLTRIAYGTASAPYLAVKCLQQLAIQEEQNFPLASKAALKDFYVDDLMSGANSTTEALDLQAQLIQMLSSAGLVLRKWASNCNELTNLIQEDLRLPNASLSIDDGTVKTLDAFIAALKRFISRRGKCSDIYSDCGSNFVGAKRKLMEFEKLSKSKTTIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5C8</accession>
    <name>A0AAV4P5C8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element tc3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RF55_24064</name>
        <name evidence="1" type="ORF">CEXT_468881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004058">
        <property type="protein sequence ID" value="GIX91770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5C8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11818" checksum="462968907568301D" modified="2024-11-27" version="1">MRDSKGSITSSALKKMMKKFEATGSLASRQRSGRPSTAAAVATTVEQTVQSMSAIAAHGGVQVLEKFRGRQGVSYGSVWKALRITLKRYQYKLQHKQELNPPDFDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P745</accession>
    <name>A0AAV4P745_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_582451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004168">
        <property type="protein sequence ID" value="GIX92859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P745"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8007" checksum="CC4BFEA621CD4E40" modified="2024-11-27" version="1">MPSTVPHENLEKAVVTCYVVVSRVGLRLTDSQTTSRCTTIDWDQCNLAHLLAQNLKFKKFGQYVTATAFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PMB8</accession>
    <name>A0AAV4PMB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_689051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004633">
        <property type="protein sequence ID" value="GIX96342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PMB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13394" checksum="9A33BAC532E63B20" modified="2024-11-27" version="1">MVHSGLAFPNKKILAQIPTNDIELKGTGRLNLFLRKFCWVESRREKDSIPPNASLGYDRSKLCEHQEIQLRLGQRQVFFHGETRFTLVNKALSFYHHVIIMSTSTSSHFLNKYFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PP13</accession>
    <name>A0AAV4PP13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_398841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004832">
        <property type="protein sequence ID" value="GIX97878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PP13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11819" checksum="A5547553EFD159A3" modified="2024-11-27" version="1">MIRLQHRVVLQRYSPPHCVSLVFPVILRYSLSIIFTGCPYAMSSDFTDTLDKSDGGSVKHALFRISAIGETEQKSSRKKSISFYKSVAKHPIALNPFLYLYDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTC0</accession>
    <name>A0AAV4PTC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_542601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005012">
        <property type="protein sequence ID" value="GIX99170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9185" checksum="6DFCA14F86B9BF41" modified="2024-11-27" version="1">MIENAAGEGVGRAADPSPATWESDPPGPIRQTHRLTIKAPPLAAAGSRYHRLLLPYAAEDPFVTHNVHSRGIDAFMRFVVCNYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW49</accession>
    <name>A0AAV4PW49_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_737631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005182">
        <property type="protein sequence ID" value="GIY00464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11819" checksum="963A9749EF56C819" modified="2024-11-27" version="1">MNPRDNDFDNSVNPHAPNSLARYIEMRRRRLQAFFFFFFISCFISKGSCGVILIFFSLSDSNPEGLAATFSPSPGKSWGEEMKRERVRASCRKWLSGLSSGGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZJ9</accession>
    <name>A0AAV4PZJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Sgk1</name>
        <name evidence="9" type="ORF">CEXT_708631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005348">
        <property type="protein sequence ID" value="GIY01629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000065">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="8">
        <location>
            <begin position="277"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY01629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="347" mass="39825" checksum="33FAADD058071EAC" modified="2024-11-27" version="1">MEGNVYAVKVLQKKMILKRNEKNHVMSERNVLLKNLHHPFLVGLHYAFQTPDKLYFVLDYVNGGEHEAGMAGILNSLFRSLRKLSSRTLFDDATNPSLTYKDIKTFFHLQRERYFPEPRARFYAAEITSALGYLHSEGIIYRDLKPENILLDFQGHVVLTDFGLSKEGLTEKDTTTTFCGTPEYLAPEVLRKQAYDKSVDWWCLGAVLYEMLYGLPPFYSKDTLEMYQNILNKPLRLRTNISIPARNLLDGLLQKDKNKRLGAVHDVEDIKKHDFFKVINWIDLEAKAILPPYNPNVRGQMDLKNIDPEFIREPVPASLSRSQSLSASVQDADVSFVGFSYAPPTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q680</accession>
    <name>A0AAV4Q680_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein unc-79 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">UNC79</name>
        <name evidence="1" type="ORF">CEXT_345321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005635">
        <property type="protein sequence ID" value="GIY03867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q680"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024855">
        <property type="entry name" value="UNC79"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21696">
        <property type="entry name" value="PROTEIN UNC-79 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21696:SF2">
        <property type="entry name" value="PROTEIN UNC-79 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="304" mass="34394" checksum="CF0A98573F838128" modified="2024-11-27" version="1">MQHYLNDALEFVADVHTLTKVKNTLYGNGIHLNEETLGGHLKAGLSQFLAIEFSKNNGRDNRVINRYLPWLYHSPPTIQGPKEFMDCVSHIRLLSWLLLGALIHSALMQTPSTCQPIPLELYPSIAEHIQVILTGFSEQSKVSVLHMSSLFHAFILCQLWTMYCEHMVALNPPGSEQNQVCGSILTDFWVKVMPGILLLVCHSKLAEMVSLHFLSLMEALQECNSTILARLLPMWTPILYSFQGHLSGNLHLRLQACINCCPPTRSKEETAAISTTFLRWLQRLQFKMGQIELQSSTATQFYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6P6</accession>
    <name>A0AAV4Q6P6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_566581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005656">
        <property type="protein sequence ID" value="GIY04032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6P6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12601" checksum="06EFB77DDEF22A6F" modified="2024-11-27" version="1">MKMQSSLVSLRYSFDREALLSFNQYWESALSVQDRKTSQKLLLVTALAQRTIPLFNQHRDSALSVQDRKTSQMLRLVTALAQRAIPSFNQHRKSALSVQDRKTSQNRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9B5</accession>
    <name>A0AAV4Q9B5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PIK3R4</name>
        <name evidence="12" type="ORF">CEXT_690031</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01005981">
        <property type="protein sequence ID" value="GIY06608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase 2A Regulatory Subunit A helical" evidence="11">
        <location>
            <begin position="19"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="500"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY06608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="649" mass="73264" checksum="DFD6561E3C7D3775" modified="2024-11-27" version="1">MTYSDMEPDPDSDALLDENERVLYNKVSYSHELQALQELVQQSVTTLLSDPENAVKQTLLERGIRRLCVFFGRQKGNDVLLSHMITYLNDKEDRHLRRAFFDAIVGVASYVGFQCCPILKPLLQQGLTDSEEFVIAKALSALTDLTEKELLQKQMLSQLLDEAIPLLIHPNLWIKQHAVGFICKVAEKSNCADVMCKIIPSLKLFVWNPEKLIPIVQVDQPVVVLAALNKPLPRSIYDYLIKLPTLRNIIECLHERKVSRSIARSGHPPSYREMEPGLLVVYTRLQSDGMTEKIEEQILLLKDHLLKVQAKKCGYDLSTSSSEKESGEINLPSLPHQVHFVSLVNPNNGFEKSFHEIQNKKGSKKKTGVDSVMNEEWQHMFANTDSKAPSSPKLQHQNSDNSLSSSSKMLAYGKSTDESLEIITAMDGKISPNQLSVIEDLKPNHCAPCRDELYALIHKKQEEYESDEIARLASEPEYKEEKPLSKKNIKIPSGHLIAHLHEHRGAVNRIQVIPSTPLFATCSNDGTVKIWDCDKMEGKNMANRSRLSYNRLDGPVSCMTVCQNTQSIAAASETGNIHVYRVVYDNLKSNLLYTRNLDPVEEGCVVDIDYLILVANLFWLMLQLLDLLLGGIYVPLVLLGSWKMIHIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDV1</accession>
    <name>A0AAV4QDV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_712671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005962">
        <property type="protein sequence ID" value="GIY06462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="10817" checksum="3989973F73BD0F75" modified="2024-11-27" version="1">MRDCLGSIYAGLYLGSIYRIVPRSIYAGLYLGSIYAGLYLGSIYAGLHLGSIYAGLHLGSIYAGLHLGSIYAGLHLGSYYAGLHLGSIYAGLHLGSILRDCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QI45</accession>
    <name>A0AAV4QI45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_191961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006330">
        <property type="protein sequence ID" value="GIY09090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QI45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19227" checksum="941A9CD7CA4E6ECF" modified="2024-11-27" version="1">MTSWVGCHNAISSRLLISAANDYFCSKSRGRKHHQFCPSTPKDYSLITSGYQQLRIGILSPMKEFLTYGCNMPISAIDRGIFHSASYAQFSRRKKKESEATITYFHLTEPEVLFVNAIESQEESNYFDGFGLHPVVNSHQCVRRFGENHLEALFLCSRRICCSPLMACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QI55</accession>
    <name>A0AAV4QI55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_585131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006178">
        <property type="protein sequence ID" value="GIY07944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QI55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8940" checksum="6E0F3850B9E87BA5" modified="2024-11-27" version="1">MTAPPVALNDADTIWRLFPTVKLNYFWWSKVAPGEQQIRLQLLSCKCVPLFGMTSESEVVCLGMQKKQLDEYNAGNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QLT4</accession>
    <name>A0AAV4QLT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_464682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006428">
        <property type="protein sequence ID" value="GIY09794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QLT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19613" checksum="FB71AA3E4449333A" modified="2024-11-27" version="1">MVVTSEKINSRAKNKGYGQREQRKINSLPLLPQICEGIQLYDQGALNQNGLASQVLSPLGTGGGYPRPYSSPVSPFPLQPSTWMHPPQQYILQQSLPPMISSSLDPLHYGALMPQLTAHLSQLQLSEPRMWPVLHMPTPATPLHPSTPRQPTSRYNLCLPWKILWVLVFKTMELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QM14</accession>
    <name>A0AAV4QM14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_155291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006603">
        <property type="protein sequence ID" value="GIY11078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QM14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8876" checksum="11F763610187F0CC" modified="2024-11-27" version="1">MKNSILNKVILRAGVRIRRSNLPFKSKHPEEHLGKVEGRVFTFSPATNEREKAGRESRSWRPSHHKKNQILPQPLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQB7</accession>
    <name>A0AAV4QQB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_414311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006421">
        <property type="protein sequence ID" value="GIY09753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9393" checksum="343DD2F0281FCB98" modified="2024-11-27" version="1">MHKIRSPVTKLLRPKVMCAAINQERSDPLVNATRNKRSDNDVGVIDLTEMILQQRQPPLYCTLYFAPQYATKRCSNMDVLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0Z5</accession>
    <name>A0AAV4R0Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007053">
        <property type="protein sequence ID" value="GIY14274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11986" checksum="03BD4427268025AA" modified="2024-11-27" version="1">MEVLHRKSQMRYALLVAKYHTKESDMHHSDITFFFCTKELKLEFMSDMCRTDLVDIELGLEASVLNAKLDKGCRTESFCVLSMGWARYIYRQKPLSASKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R128</accession>
    <name>A0AAV4R128_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_103501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007142">
        <property type="protein sequence ID" value="GIY14776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R128"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11334" checksum="163DC36A0F5E21AB" modified="2024-11-27" version="1">MTIVNYSVDSISIKATNSPAFRPDTGHRLFNHLYLSGNALLGGISGANPSFPFYCNFQQSEGEGGCTNSLLSNYNGGTPLQHRTVLIISRVTREDEMTRQTDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2J4</accession>
    <name>A0AAV4R2J4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposable element Tc3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tc3a_34</name>
        <name evidence="2" type="ORF">CEXT_784551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007218">
        <property type="protein sequence ID" value="GIY15271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2J4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14831" checksum="97AC4DCB7C1B67B1" modified="2024-11-27" version="1">MFSDESRFSLQSDSCRTFIWRAPGTRYHQENTIERHRYGGAGWLVWGGIILGSRTDLHVQSVTMTGHIYRDVILEQHVRLFRGAMGAEFLFMDDNARPHRANIVDEFLQLEDITRMDWPAYSPDLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RC31</accession>
    <name>A0AAV4RC31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_191611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007529">
        <property type="protein sequence ID" value="GIY17643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RC31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9431" checksum="0E0C3DC43B70B19E" modified="2024-11-27" version="1">MGSEGRRCKGLEAKQDAFRRNLLLPDQEKVRRRRTRRITRTQGQSLLLFIVYALGRCAAEAVFELLEISISVDRELISALKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCM7</accession>
    <name>A0AAV4RCM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 4.1-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">epb41l4a</name>
        <name evidence="3" type="ORF">CEXT_749491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007553">
        <property type="protein sequence ID" value="GIY17838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13186">
        <property type="entry name" value="FERM_C_NBL4_NBL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000002">
        <property type="entry name" value="Band 4.1-like protein 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014847">
        <property type="entry name" value="FA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018980">
        <property type="entry name" value="FERM_PH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280">
        <property type="entry name" value="4.1 G PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280:SF4">
        <property type="entry name" value="BAND 4.1-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08736">
        <property type="entry name" value="FA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09380">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01195">
        <property type="entry name" value="FA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01196">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY17838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="481" mass="56105" checksum="796799750EF5B9E8" modified="2024-11-27" version="1">MSFLERVRWLDMYGVDLHPVLGDDHVEYFLGLTPSGVLVMKGKTILNHYFWPRISKVFFKGKSFMIRVKDKTNEETTYVFLASSREACEYLWKCCVEHHAFFRLTQVKDMTGNPLQIFRLGSKYRYSGRTEQQVRSETVRRPPPPILRVPSRRFQKRPTDADVQEKEAFKKSLQGNTKDDFYLTRTEPPPNPLYRSVSTPAVLSESLSLKSVNTDIAPWEDPNQRGLFGSRRSRRSSSADSAGRRSHRSRRSSDNESEVSRSSRDSRSSRRRGRESGSESDSQHHRSRQRKRSRRSEYRLVDSESQWRKVQQRKKEHDTALQSAVVRDLSKKKSGYMNSGLDTESEAPPKHRKKHRRRSRSGSRSPEALPKEVKRHLRYQLEDASHLTEEEKRQIKYTRVESEKEIFRLHYSPASGRLRRRKVSPASSRNSLDMTSKGCREGIPPDTHSLEDRLPRCCPPLFSNRTDNFPDERTVPYSNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQB7</accession>
    <name>A0AAV4RQB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_689331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008294">
        <property type="protein sequence ID" value="GIY23602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13318" checksum="74E2BFFA64372788" modified="2024-11-27" version="1">MMLITICNPLRKLVSSCKCIQESTLARSIYQDPSRAPFHQTSLLSAAACRKCGGCLPRMDVCISCHKYDLLRLSALSRRICLKQLASDQVGCTLGSLLGLNLVFCSLLAEVRLGKDSAVARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRY6</accession>
    <name>A0AAV4RRY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_267281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008386">
        <property type="protein sequence ID" value="GIY24334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10590" checksum="C6D34E424023C13C" modified="2024-11-27" version="1">MFYARDYSIPIRRSGKTFRTLDGCLRRDYKKVMSHPVLERIKRGIKLSLPLTVARGPPIISLEDYHVSELRFTLCMTMSLFIPSDLEITVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZ04</accession>
    <name>A0AAV4RZ04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008569">
        <property type="protein sequence ID" value="GIY25712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZ04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11550" checksum="5B6A3287E38B684D" modified="2024-11-27" version="1">MEEIIIDMEKVFFFIPEIDLYNAQSFLSKYHEIDLIKPHSYAVDAVTKYRKFISWWNFVRNTPRIMISDFRLLFHFMKTCKLPFEKFSEDIESLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S822</accession>
    <name>A0AAV4S822_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_243681_1</name>
        <name evidence="5" type="ORF">CEXT_540861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cut8/STS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009253">
        <property type="protein sequence ID" value="GIY30623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S822"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY30623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="35158" checksum="D184618D6459660F" modified="2024-11-27" version="1">MAGSAGRRNILRELGAFGHDNDLTHHQIVEIIPVSPDEAVIHERGLHRKSPTYNYGASDPIFFKTPTKSPKKSPAHARFLTPTKTPPARSSPRKRSNNATPDKLGFNDMSLSCKSELNVKPNPILEKGLKAFSHEQLIQLIRDAAEFSPEVKQLITQLLPEPDLKPIEERLSKLKQNVYKSFPRNIWGSQESSFCFMRVKTHLEAFRKECSEICHHFMDSQHWPAVFEFIFIAWKYTLDLPHWDTSYHNKIKNNCMKYLAAQCVNALKKANLNKSALTEIIERMQEFSDEPTIKSCINFAADMVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDX5</accession>
    <name>A0AAV4SDX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_219941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009414">
        <property type="protein sequence ID" value="GIY31687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10874" checksum="3F196C47C182F5BD" modified="2024-11-27" version="1">MLETIQSLAETFSCGLRRRQSTTMLKRPLPPSTLPPWRANFLCFEGHLTPADPIFSAPYKVVTLNRHSDNGCQLEKRENQLESSHNESEVKVFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJ85</accession>
    <name>A0AAV4SJ85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_163731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009563">
        <property type="protein sequence ID" value="GIY32891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJ85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8168" checksum="AA397411BFD23CD2" modified="2024-11-27" version="1">MHGNLDNIHVKPLVGQKREQCTISVLFSRNGGPQSGVADESRNIYIELDRTKTDQCPFWRPSSLLKREDGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SN31</accession>
    <name>A0AAV4SN31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_416841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009680">
        <property type="protein sequence ID" value="GIY33752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SN31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16930" checksum="1E825248AAF3A860" modified="2024-11-27" version="1">MAGCDWSRGRLKFLAVATNWADPRHSDYIRYKSTPLYTLLDYRQRLAEIKTPPTFRTTTTTKHSFVLPRDTAGKIERKEKNSFPWKRSKKLRGLLSSVCSRYNGWVQGASVIISSGLKGKGEFCRNSEISLTTTTTTSLASFITREQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STD5</accession>
    <name>A0AAV4STD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_275091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010072">
        <property type="protein sequence ID" value="GIY36652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10288" checksum="BAF76F3D0997B8B6" modified="2024-11-27" version="1">MARNLAVKLIVINGQSLSRVAGFRTVKFRHCKEPEDRGRGRDVADSASVLTRCRLNDSKIKKAPVWCSGHGAFTIFSIFSLQESLSLSLYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWK1</accession>
    <name>A0AAV4SWK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_746171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010264">
        <property type="protein sequence ID" value="GIY38140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18387" checksum="2D9D0327007FE90A" modified="2024-11-27" version="1">MFTNAWAFTDVLHSEQPLVTGEKDPVNTQSRLDKARKDIIKKFAMGDLLKGGGVGLMRVEPKSLPRATQLTVVRHNKHLVDDYKVSPSQRTTNEAERYFKTVMNRKLPHLLCCTWLHLFTPKYLGKKTPLTRKVVWGRPEKTSSRSLRWGDLQEEGEVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SX82</accession>
    <name>A0AAV4SX82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_736521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010323">
        <property type="protein sequence ID" value="GIY38554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SX82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8682" checksum="44ED7DBC4419DA78" modified="2024-11-27" version="1">MTCTVRLSRDSDYCICFRRRGCVSSDPFGLIISFKRVVIGLVCWARKRVGFELSGKVDSKRCSMAEREDDVKLIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXD9</accession>
    <name>A0AAV4SXD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_674161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010356">
        <property type="protein sequence ID" value="GIY38790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8819" checksum="620E8641D647D3BA" modified="2024-11-27" version="1">MKKLRTISHHNSPPSCLIHPSEGVEIFSRGVHHFIGPSPTRVGLKLLRFHLRYLALWGRMLSVRNPLHTELCSLSGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1L6</accession>
    <name>A0AAV4T1L6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_409681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010324">
        <property type="protein sequence ID" value="GIY38562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10696" checksum="DCDC674349FEE7ED" modified="2024-11-27" version="1">MRKSPLLDWTSCPADKRGLPLYIWKEVLLYYRNVLWRYSRSRTHPLSQNKDFLCHYRGMYYELGSTVSLSTKQGIECTCKVPPDFTCVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEK8</accession>
    <name>A0AAV4TEK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_573901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010956">
        <property type="protein sequence ID" value="GIY43302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9861" checksum="23B17CCB2ABD3F0C" modified="2024-11-27" version="1">MLFTAVNVKTLIAPIDGWCFKALHYIRNTLKPLSVHNEYPLISTYSAVTWRMEFKQFVRVRPAFPVSPKRCFALRFHSQMTSPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TP62</accession>
    <name>A0AAV4TP62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Fibrillin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Fbn1</name>
        <name evidence="12" type="ORF">CEXT_223101</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011544">
        <property type="protein sequence ID" value="GIY47216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TP62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000003">
        <property type="entry name" value="fibrillin-1 isoform X1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000002">
        <property type="entry name" value="Latent-transforming growth factor beta-binding protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000096">
        <property type="entry name" value="Putative fibrillin 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000024">
        <property type="entry name" value="Putative latent-transforming growth factor beta-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.290.10">
        <property type="entry name" value="TGF-beta binding (TB) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017878">
        <property type="entry name" value="TB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036773">
        <property type="entry name" value="TB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052080">
        <property type="entry name" value="vWF_C/EGF_Fibrillin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47333:SF5">
        <property type="entry name" value="FIBRILLIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47333">
        <property type="entry name" value="VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12661">
        <property type="entry name" value="hEGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00683">
        <property type="entry name" value="TB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57581">
        <property type="entry name" value="TB module/8-cys domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51364">
        <property type="entry name" value="TB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="66"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="107"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="189"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="11">
        <location>
            <begin position="230"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="292"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="TB" evidence="11">
        <location>
            <begin position="406"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY47216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="472" mass="51337" checksum="F1252AD1A9D90962" modified="2024-11-27" version="1">MNVIYEGIFCENGHCINTPSSYRYVDECQNATLCQGGRCINSVGSFTCFFCQPGYDLTSDGTKCTDQDECSITGMCANGVCVNGAGSFTCRCNPGFTLSSTRQSCIDIDECSENARICLKGRCQNTPGSYKCECQEGFVTSPGGDYCLEMNVKKKGMCRHGTCVNGDGSFKCLCDPGYKLSPDGHFCIDINECSETTDACVNGRCENSDGSFRCSCNDGLTMSPNGRICQGINGECSNPSSMAVTRSACCCANRGSTTPAWGIQCVPCPTLGSKEFLDLCPKGPGLGSLVDDINECIVFPNICPNGACENLKGSYRCVCNQGYQVDAGGKVCSETHQAVFQCTCPIGYRHNVLTNTCDDIDECQEKISDICIGGTCINSLGSYRCECETGSALDASRNICIDNRRGSCWMTINSNGRCENDIKTPMLKSECCGSIGKAWGSPCQRCTDLERRCPKRICYVRWFYMYRYYVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TPR8</accession>
    <name>A0AAV4TPR8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bestrophin homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BEST3</name>
        <name evidence="7" type="ORF">CEXT_380661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Forms chloride channels.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011587">
        <property type="protein sequence ID" value="GIY47511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TPR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034707">
        <property type="term" value="C:chloride channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000615">
        <property type="entry name" value="Bestrophin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021134">
        <property type="entry name" value="Bestrophin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10736">
        <property type="entry name" value="BESTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10736:SF0">
        <property type="entry name" value="BESTROPHIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01062">
        <property type="entry name" value="Bestrophin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0868">Chloride</keyword>
    <keyword evidence="6" id="KW-0869">Chloride channel</keyword>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY47511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="380" mass="44365" checksum="A769DD4FB5FAB231" modified="2024-11-27" version="1">MTVSYSLDVSKAQFCGFTKLLGRWKGSIYKILWREFLIFCLAYALISALYRSYFSLEQKIIFEKLVVFVDSFTDLIPLSFVLGFYVSLVIGRWWGQYQTIPWPDRVCFMIASYVQGSDERSRMIRRTLGRYVILAQALTYQAVSTAVKRRFPTTQHLVQAGIMTKEEQTVFEKISFSYGKWWIPCHWFTALATRARKEGRIKDSVCLNGLLQESYDYRNSCAIMFGYDWISVPLVYTQVVTIATYMYCLALIIGRQYLDPARGYPKNEIDLYIPLFTLLQFFFYVGWLKVAEQILNPYGEDDDDFELNWCLDRSVHIAYLVVDNLQLKHPKVTKDFFWDEMEPVLPQTRHSAKFFVHPNLGSAYDLEVGDADSLPLWTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQU4</accession>
    <name>A0AAV4TQU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_159891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011713">
        <property type="protein sequence ID" value="GIY48424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14415" checksum="5DF0764B0FF44347" modified="2024-11-27" version="1">MELSRINLRKKIALIAFTDLGSLSIGKTVGVLEKMDLCQKVDIKLNRILSRHLSGHPEKRREVVVDPMGKREIKGTKVMTGIRGKVPSFSGGEGGWVQWDGEMTFPQLRIGFAREDVYPFRSGELSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUC7</accession>
    <name>A0AAV4TUC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_497821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011722">
        <property type="protein sequence ID" value="GIY48530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="254" mass="28440" checksum="1664E846934CC6DA" modified="2024-11-27" version="1">MTNPAFVKLISKGNISSDTTAKSLEGISRYVGENSSKAQGDSKYRDDESSFVKLISRGTYHQALQQNHWKGSVDMSQGILCSIFELSKVYSTVYYCPSWGILLATAIVKPRHRKEWGNYIRSGNFRKLYSTVYYCPPGGVLLAVTIAKPRHRKEAQRRSPKAIRKIATTNPPFVKLISRGTYHQTLQQNHWKGSVDMSKGVYSEEGQRRSPKAIRRIATMNPSFVKLISRGNISPDTTAKSLEGISRYVGGNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1Q3</accession>
    <name>A0AAV4U1Q3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_340501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012134">
        <property type="protein sequence ID" value="GIY51639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1Q3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="21403" checksum="B3526EEE2D4C370E" modified="2024-11-27" version="1">MVEELGAGKGGFGGTGGYGGGVGGAGGFGGQGGRYGGAGGSGKGEAGVAGGYGGGWWFWRFGQGGTEGYTVEEQVVRKRRAGCSWRIWWRRWWFWRFRWTRGAGGYSGGAGGAGKGGIGGTGGYVGGAEVEKSGYNGGNSNSGDQGEYGSSNGAAGLEGVGGYGSRQAGVVDNNHQGGAGFGSQQAGISDGHGIYIGSQRNVANGNSGNHKGTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2T7</accession>
    <name>A0AAV4U2T7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_123845_1</name>
        <name evidence="1" type="ORF">CEXT_266551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012190">
        <property type="protein sequence ID" value="GIY52059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2T7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11373" checksum="ED4D66223441BF2E" modified="2024-11-27" version="1">MKLTISFMFLDGSDELIYNLMTRLAAASNLEWDKGPGSRFAKSSEQWPKVIASEMSNRLSVLVFAQRIPFYIRNQTSYVFIIDHREFFHSKGAAVQLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U324</accession>
    <name>A0AAV4U324_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_375601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012211">
        <property type="protein sequence ID" value="GIY52208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U324"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10030" checksum="A6A434C49919878F" modified="2024-11-27" version="1">METETIRMASGTPREACSRVGWWMSTSVPGDAIEPDLIDDSCCHASHCFAAPNISLIGGSDVWRILAVALQGLVSGTGAQEVGRVSLTWLQQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U444</accession>
    <name>A0AAV4U444_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_286641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012250">
        <property type="protein sequence ID" value="GIY52513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U444"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10229" checksum="AC8AB5801E72DB20" modified="2024-11-27" version="1">MEVRFALSAEIPRLSEEASNIDTPVLLFPLKKGGNSRTMVDIPIFPVLVFRFVGVGQREPLATLLQSLDSVNNYPNKRVKVARNQFKLWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9F4</accession>
    <name>A0AAV4U9F4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pps_1</name>
        <name evidence="2" type="ORF">CEXT_666981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012514">
        <property type="protein sequence ID" value="GIY54428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9F4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11664" checksum="9CD8C6DB5622B580" modified="2024-11-27" version="1">MMRSYLKVVGLKMKLKFIYWIKWAIVYIAIRIYNALQSKRRRFDLYDIRATGDPFKLGFLTPHLEKELESPCPESHLQEAADEVLFYGVNSSRNACWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHG8</accession>
    <name>A0AAV4UHG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_35511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012869">
        <property type="protein sequence ID" value="GIY57208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13011" checksum="97ACF6934E85B084" modified="2024-11-27" version="1">MATSVKGTKTLIVPRTDPWEIFFAVNHSTLASWHHDNILHQPHLCNSRIGRKRVAGVRYFAKISPKPFYRHHLHPVLSLSTRTFVDGGRQFLYSDWNRRNGKALQEVRFSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHR0</accession>
    <name>A0AAV4UHR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_445131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012898">
        <property type="protein sequence ID" value="GIY57377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7454" checksum="36E00363AE2A6D2B" modified="2024-11-27" version="1">MATIFQRISFTTFPAFEKCPVLCDKFLSIKRKEGGMHCQDDILEEGKLGFNAGATHNHIKEAVSTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UK93</accession>
    <name>A0AAV4UK93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2_54</name>
        <name evidence="2" type="ORF">CEXT_236501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013018">
        <property type="protein sequence ID" value="GIY58141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UK93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043652176" evidence="1">
        <location>
            <begin position="25"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14486" checksum="169759683185D57E" modified="2024-11-27" version="1">MCIYLSNICVWIVNFCTFISPGLCDPNQNDQRGPVFSTEPPSRVEFSNSSGAEVRCVADGVPNPNLSWHIKEGGNAPDVPGLRYTRPDGTLVFLPFMTTDYNRMYMTLCTSVWRPIVLDLLSAERFMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT02</accession>
    <name>A0AAV4UT02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_176161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013351">
        <property type="protein sequence ID" value="GIY60619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14629" checksum="606DF6CCDE2E6E1D" modified="2024-11-27" version="1">MFFEYITEPERQVFKKAHKFLAAGKAVNCRKFLIFPGQKFCIHSPPYSSQEANFSSFANFKRAGNSPVLHVYDTAKAVRYERLSKTGKICVPGLERTLHGSGWLCIIKSGAPFWERINLCSLCPDILQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWI6</accession>
    <name>A0AAV4UWI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_734321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013618">
        <property type="protein sequence ID" value="GIY62437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10444" checksum="169CE729AB4119D9" modified="2024-11-27" version="1">MEPIAASNRLIRNSIRFVTQTADCFSCEAHEPPGAQEKEESVILAKNELSEFWERPSSIFVSKLQGLIIVMTPQIRNGALIDALLPYVRLSSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZU8</accession>
    <name>A0AAV4UZU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon 17.6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pol_122</name>
        <name evidence="2" type="ORF">CEXT_693091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013689">
        <property type="protein sequence ID" value="GIY62989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051320">
        <property type="entry name" value="Viral_Replic_Matur_Polypro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064:SF29">
        <property type="entry name" value="PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064">
        <property type="entry name" value="POL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13041" checksum="A66988B3B499136D" modified="2024-11-27" version="1">MAKLLKDCETFVLPYSDDIAIYSEAWKDHIKDLSFVLDRINKVNLRLKSSKYTFAQKYVKHLGYIVGQGLRTCEGIKVQTIKDYPPPKTKTEVRAFLILKGYYKQYILLCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V450</accession>
    <name>A0AAV4V450_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_65471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013892">
        <property type="protein sequence ID" value="GIY64548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V450"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13797" checksum="C70E7AC8386AE4A5" modified="2024-11-27" version="1">MNRGGRIIAPNDKAREYEESLFPEYFKAMSSPEQVLAYRMAKRRNMGEFLPTTCHCRTQQNVPAKRINVHLSHSSRCFQFDVFCRIFSRASFSGCLTGSNEPSTSSTLASGLTESVLAYLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VF07</accession>
    <name>A0AAV4VF07_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_303681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014406">
        <property type="protein sequence ID" value="GIY68589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VF07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774:SF3">
        <property type="entry name" value="BTB (POZ) DOMAIN-CONTAINING 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="25"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="321" mass="36563" checksum="14706C8720B7793F" modified="2024-11-27" version="1">MANADLEPSGLIARTSALLNNSVLSDVEFHVKNGSNIEKFHAHRLILAVSGKGFFDLLSNATNSSTIIKISDLSPHAVYLMLKYLYTDSLSLLKMEDAIELFRLAKKYSITDLEKICCKYIMKEEINIDNLFVKYESALACNFDELLQNCRKLVQSETKAVFASKYFGHASFSVIEDILSQNCLNVSSELEVIHAALKWSECECKRKGRPTEKICVRDAIEPLLKYLRFLSLTADEFCDFVEKYNIFTGYESTLFTRKILQPQTNVPLSKQFCSITRPRQAYARSNSSMVNATNFNDYYADFLKSPDPFLLKNMSSHHQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGC5</accession>
    <name>A0AAV4VGC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_722581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014502">
        <property type="protein sequence ID" value="GIY69176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10016" checksum="88BE04443B35CB77" modified="2024-11-27" version="1">MKTYYPLRSKFLSPATQPSSANISPGYLCQHLPETASFFFLQEPFHRERAKSPDSAGLVLGHADDLLNNARGRRCIQIRQSNLQPFPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLN9</accession>
    <name>A0AAV4VLN9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_25295_1</name>
        <name evidence="3" type="ORF">CEXT_346401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014753">
        <property type="protein sequence ID" value="GIY71081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY71081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25380" checksum="C333839BB7192F22" modified="2024-11-27" version="1">MEQPPVVVDQDEDTEIMAGEEISSMSDGPISFVGLFNTQKENNVAIKEENSHQEHDLKEVQEPTVIKEEVCANSDKQNNATGIDINNSISLFKSKKKKKDHIRKVPILRIKTHKCTHCKRQFRSIYTLRYHLRSMHDEKVYLSPALESRLKKRRWIPPHVRLQKSKVGSSGSLSHKHKSNSLKEKPYSFLPTYPNEKIEQKVLFSDFSKLFRCFTSISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VR21</accession>
    <name>A0AAV4VR21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_496251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014965">
        <property type="protein sequence ID" value="GIY72578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VR21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY72578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="16945" checksum="510E559551C1B7BC" modified="2024-11-27" version="1">MSHTPSKGSHYIYDRIGFVKYSTFRRNKCRKKIGKALLTSGSENLPPIHFEEEIDDRASADPRRKTQRVLENIDFLRNKCRKDPGKTSWLLAAKISRRSILKKKSTIEHQPILGGRRRGPSPPHDREPGKTLSPDLSISPTSLASLSGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VW70</accession>
    <name>A0AAV4VW70_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_233691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015246">
        <property type="protein sequence ID" value="GIY74692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VW70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043641030" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11863" checksum="C0266CAD43D02E91" modified="2024-11-27" version="1">MLKSILLLFFVSCASVFCQDTTLLPIQKEKSHSCLYNFFRSSPFGSHVTRVTFHSTGVSQHQYSNEFWGRLKQKRRATDFPIFINPCSQSNQLLQGGVSRGRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VX05</accession>
    <name>A0AAV4VX05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_246411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015282">
        <property type="protein sequence ID" value="GIY74976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VX05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8361" checksum="528256B16E2D5257" modified="2024-11-27" version="1">MKKALTCTSSSYKSWIPSSGTDSINNANVYVNVCCLLCSGLDEQFATSIQQDPNDTFIDNILHVPLKRNISNGHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VXS2</accession>
    <name>A0AAV4VXS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_494061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015304">
        <property type="protein sequence ID" value="GIY75152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VXS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10395" checksum="D78C58F45AEC4BD6" modified="2024-11-27" version="1">MAFCYAGETGISVSPVKGEGGSHNPGGRCPGPNQSRLRPSQGVRGKPDSRGMITQLFLLPLFQRMIGLITGERGSHGPCTPYSSFVPFSESYLLQHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W1P4</accession>
    <name>A0AAV4W1P4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_572221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015416">
        <property type="protein sequence ID" value="GIY75916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W1P4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043562591" evidence="1">
        <location>
            <begin position="24"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11288" checksum="8BF392CB17993C51" modified="2024-11-27" version="1">MTNLTSKQMMLLFLIKIANSINAEEIFKTNSLLGTKISIERFRGSNTAPQCRNCYGFHHSSETCHLKPRCAHCAAVHLTADCSQPKDSNKICANCNGSHVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W943</accession>
    <name>A0AAV4W943_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_390781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015740">
        <property type="protein sequence ID" value="GIY78319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W943"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14475" checksum="7EFB2AF735A3BE9D" modified="2024-11-27" version="1">MHTQQQFLPKTSPKKKRRRKSSSTQFGNTFHIAYFCAISFEPNGINHLNNAYPPAISTDDQTPKRRPERKSSSTQFGNTFHIAYFCAISSERAQPFPNGLTGSRSELENLGPRVATSENLIKQTVCVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBM5</accession>
    <name>A0AAV4WBM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_742861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015834">
        <property type="protein sequence ID" value="GIY79008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10310" checksum="DA53FBDB28F34921" modified="2024-11-27" version="1">MAIENPSSSHPDKNQTQGYKVGRQMVHTPQCIALPSRGMVAILLVESKDLTYVLTPVNLQWEQKRLVCFSTTATQPEVHVCLGVRGRQFRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCT6</accession>
    <name>A0AAV4WCT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_609951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015940">
        <property type="protein sequence ID" value="GIY79880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8014" checksum="433A9850A7BFB0D3" modified="2024-11-27" version="1">MRLHTIRHPTKEALYSSGSLSFQASDLRVLFKVRHKTELGYSEAIRGNEICECTRCQLAGFLNLMVASGTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WE30</accession>
    <name>A0AAV4WE30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">LITAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AVEN_275295_1</name>
        <name evidence="10" type="ORF">CEXT_642141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Lysosome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CDIP1/LITAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016015">
        <property type="protein sequence ID" value="GIY80484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WE30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037519">
        <property type="entry name" value="LITAF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292:SF6">
        <property type="entry name" value="FI16602P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292">
        <property type="entry name" value="LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="9">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY80484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8361" checksum="557B266D6A16D089" modified="2024-11-27" version="1">MLFGEYPVQVTCGNCCRTIVTKTRTARGFCTYLAAYIVCIVCCPCVLIPLCSKECKDVHHFCPSCGTMLGVYRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFH3</accession>
    <name>A0AAV4WFH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_123831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016003">
        <property type="protein sequence ID" value="GIY80358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10277" checksum="CFAB9F85DF0FF1CD" modified="2024-11-27" version="1">MSGFHCVLTAIGSVSTHLNLPGAHQYGGTGKPIVLSRPIARKQLFLPSLYTHGTRVIADYFLGQRSFPRKVIIIRRAKAIGCGSNHRMMRTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHN7</accession>
    <name>A0AAV4WHN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_117911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016108">
        <property type="protein sequence ID" value="GIY81319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12832" checksum="2338A7332BB25C9D" modified="2024-11-27" version="1">MDGLCSLFPSFCMLLVPSMYGLCFPASGKNVCLWFHLCMDYVSHVEPVSVFLCALVPSMYGLCFPEFRLSTCLGFHLCMDYVSLLPSFCMHWFHLCIYVSHFRLSVSLGSIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQZ6</accession>
    <name>A0AAV4WQZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_541751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016505">
        <property type="protein sequence ID" value="GIY84346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13310" checksum="EC4D7962E97489BD" modified="2024-11-27" version="1">MFNALIRCKSLPHVKMEEGRGKNRKLKGSALPMQVSTSLLKSEKRANTEGKKKKGTHLLRLQIVLELPAAAIWRCHLVSVNYVKKCAAPSKIRNKKPRFEFCSPKSFSQHCQDIFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTH7</accession>
    <name>A0AAV4WTH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_592871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016729">
        <property type="protein sequence ID" value="GIY86022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="64" mass="7449" checksum="AC3365C6F218D720" modified="2024-11-27" version="1" fragment="single">MIGAWRSPEKNTRSQGLARFNPGREAALHRHALGSVRQRKCPTRRFAGFYFTTVRSFWRPLCRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTV9</accession>
    <name>A0AAV4WTV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protocadherin-like wing polarity protein stan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">stan</name>
        <name evidence="12" type="ORF">CEXT_492351</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016676">
        <property type="protein sequence ID" value="GIY85689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005911">
        <property type="term" value="C:cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000033">
        <property type="entry name" value="FAT atypical cadherin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000092">
        <property type="entry name" value="Protocadherin 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050971">
        <property type="entry name" value="Cadherin-domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24025">
        <property type="entry name" value="DESMOGLEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24025:SF23">
        <property type="entry name" value="NEURAL-CADHERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="7"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="217"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="11">
        <location>
            <begin position="313"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY85689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="518" mass="57492" checksum="7C815ED4997AE153" modified="2024-11-27" version="1">MTKYQRSSTLTRGTINENAPSGTPVTVEPPISAVDNDSGKQFRCALFPEWSRQRIVQDPRKRPGHLQLPQTPILTLDRERKERYDLQVTATDMGNLSSSTYLTINIADENDNAPRLPARAPEGDAAGDRPAGIQNCRGQCLDADAKGPNSKVEYIITAGDKGDVRIDRATGEIYVVSTLRPGTVYLLNVSAADGKGLARLDGEHHGGGRERPQAHLLQAVDEDTGNNGMVEYSLVTTTFEQKFPFTVDSKTGELFAQGIIDRESKSSFKYQVLATDFGEPQLNSTADVIVEVIDVNDEPPRFYTRSIPGACAENLDPGQKVTQITAYDSDSGNNGLVFYKLGVGHNNKFYIDSKDGTVWTLSTLDYEKQAFYNMTVIAYDQGTPKSEFHRQIVGDRRRYQRCRAGIFESSVHSRSRRSRQPGDTVFKLDAGKGDFKYALLNSDEIDAFDVDMSTGDIRLVKALDSVQQSHYRLLVEASVDSDPPKSDTAEGKHHSWNRPWCTIVPGRRVRSDRLRKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X463</accession>
    <name>A0AAV4X463_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_383301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017212">
        <property type="protein sequence ID" value="GIY89473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X463"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9086" checksum="07B8DB14D6344B17" modified="2024-11-27" version="1">MSDGNGHSSIQYVCCETAGLLGYLSSEWAFIAAWSGWSKQFYSLRRSLSIHPVDPSLWTLQGENPHSLSPRSLFPQSLPTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8S4</accession>
    <name>A0AAV4X8S4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_80720_1</name>
        <name evidence="6" type="ORF">CEXT_421111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017315">
        <property type="protein sequence ID" value="GIY90361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056707">
        <property type="entry name" value="DUF7805"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF3">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25090">
        <property type="entry name" value="DUF7805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="640"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="135"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7805" evidence="5">
        <location>
            <begin position="441"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY90361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="691" mass="77924" checksum="0A668ACA9644542D" modified="2024-11-27" version="1">MIERSVTFFSQGSNVSVMAVVPSRASIPSTSFSLYLTYRVVKFRKLFLVPIQGLTVTFFIGFLNGEDCYGVGVVIPTPNLEDQFLKRRPFQESEKTSFLGQPVANTYCDREFLDCHSNRRWGYTARIVLSQPNDYKISVPTGRATSTSGTSFLLSTDCLSGDSVRIYDGPSIRSPQLLEFCGSGSLPEIVSSGNEVLVQIYSAPYQHLSNSRVEIEVSVSSPLIFSVGETGPRLCAHAADYPPKYLPPRPCEVPNESYLSVGSEMIIRHRFLSFASELLTSSTSSFTARYEFIDTNQQGTQIDHSQCDRRIDSRLGKKGAISTLEISSYMEEVDATILHACFISWAFQPRGHGCRMIDIRQGIPQSQTWSLLGASEHWAGYSSPVGCVCDISIEKDHQAMTFESVVSNVKLNFEVFGMSHLEDFEDYFFEIDYEFVNYSLCDIGLRRHSGLSGEGILSFQSPSSQLKVPSPKPIRCRWKIEASPHKHLYLKFKGFNASASEECQFGTRILVYLDPREKPIANACIDSDKSGQKTDELMEFDIFSHTWYNESRDKIHEQERDRLFVEMVAPHDSAAFVIQWLEVTRPFVRTQSGQTLRNVDCLFECPEIGACIDPELWCDGTVHCPSGFDESPDHCKYFPVTYVSCAAAGIFITVLVLIWFAVRRRRLQKLLKKKDIRQFPPDDYCVESPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEI6</accession>
    <name>A0AAV4XEI6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Immunoglobulin I-set domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_12861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000267">
        <property type="protein sequence ID" value="GIY93445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7677" checksum="35E14A04ED887155" modified="2024-11-27" version="1">MVQSVTGIGKQASLMCLQKSVQGHVYLTKTDLDTEGVYRCEASAESPTFQTVEAENTLKCLSSHRKILKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFS1</accession>
    <name>A0AAV4XFS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_379461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017722">
        <property type="protein sequence ID" value="GIY93927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25091" checksum="9FECD793882EB23D" modified="2024-11-27" version="1">MQFNSSEVTNLFSPHLKIYTRISTHRSTIEGWKKIAQKSSLQPIKPLENRSIPKTSWALKKFPLAKNGRKDQDKLGKEKWMSRAFACRNADPQAYRGRTKINWEKVMDVKGICLSKCRPPGLPVCKEGKTEQAETILLLLVPCNLIPVKTQKLFSPHLNIYTRISTHRRIEVWRKEEKSAEKFSAAHKTTRNRSIQKPVGLVKNLLLLKMEYPVLGSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFW6</accession>
    <name>A0AAV4XFW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_37821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000179">
        <property type="protein sequence ID" value="GIY92673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17414" checksum="DC37A21F82EBF845" modified="2024-11-27" version="1">MSSTLNSSSVCVLTFWQYVFSKKKRQYHIGDSIEKCAYCLWISLFPSEMVRRILCYSSLMQEFAQDFGRKMEELLITYTIPSTLNSSSVCILTFSQEELIPHRGFHTKMRLLSVDISFLSEMVRRIVCYSSLMQEFARDLGEKMEEVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJG7</accession>
    <name>A0AAV4XJG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_416351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017739">
        <property type="protein sequence ID" value="GIY94065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20606" checksum="B85DA7D92BB44B40" modified="2024-11-27" version="1">MGETCLPIFVEECQRTSISYCSLDSDLLKITGHPIVEAFSRLYLTITTLNQELIPDLFQQSAQICAGYEELSTDVGELPRCLADDILGTEIVEMFRFGWIGDSCVNGTVCHLGYSYPETPPLSAITLSTLALMGRTPPLEKHPLTISFIFCFVFVVALLNRNFCPIFLRNRFVVWFVLVFNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN66</accession>
    <name>A0AAV4XN66_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Galectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_18739</name>
        <name evidence="4" type="ORF">CEXT_68631</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018062">
        <property type="protein sequence ID" value="GIY96565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00070">
        <property type="entry name" value="GLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044156">
        <property type="entry name" value="Galectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001079">
        <property type="entry name" value="Galectin_CRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11346">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11346:SF147">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00337">
        <property type="entry name" value="Gal-bind_lectin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00908">
        <property type="entry name" value="Gal-bind_lectin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00276">
        <property type="entry name" value="GLECT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51304">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Galectin" evidence="3">
        <location>
            <begin position="72"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Galectin" evidence="3">
        <location>
            <begin position="216"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Galectin" evidence="3">
        <location>
            <begin position="347"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU102079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY96565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="520" mass="58308" checksum="261E5D0571448781" modified="2024-11-27" version="1">MRGGGEETFYFGSFESRSVFRRWHWVRGASVFSTKPTETDLTSNLSHILSHSLSFSQLISFSCARDRKTVPHACSIPGGLCIGSKIYIHGMVPKDASQFSITLQRGADVEFADLHLHLLAKLGRSPVVVRNSRHGATWGVEEQLPGSFPFPEFPRSFLLIITAYMDSYEIEINGSSQFSLKVRDGLPISAITHLAIEAELSVRAIHIPVENMPRNLRLSVGSGLKMGDLFSIKGQPTEEAKNFTINWQSGPAKFDDVLFQLNPRLEEDRVVRNSRLDDEMGKEESTPEMPFKPNTPFDLVVGVRSLDFETRLDGKEWIPFGHRYDVGAAKTLFLEGDMQPSDICIDLAQLNPSGVLNGTNIKSRGIRLHQMCPVGPFSNSHSDTIDFSSDWGIRKRLLAFAFGQSERSPFKMQMTVQCGEGSEDSDVALRYLVQWEDDGSPKITLNSREEDNWGQEVKSRIDEGFYPGLAFDLLVARTDDGLRCFLNGTEHALFPYRLEDQKPDHVTVCGDVELQRLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPU3</accession>
    <name>A0AAV4XPU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_394241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000572">
        <property type="protein sequence ID" value="GIY95748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8591" checksum="3D08DFF5678152E6" modified="2024-11-27" version="1">MTSVGLWVVLGENPAWRRMGISEPYFGVEDSSLIPTVILVSLQSLERREREERKKSLSHWGQSSGSKRSDDIIKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPY2</accession>
    <name>A0AAV4XPY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_60442_1</name>
        <name evidence="3" type="ORF">CEXT_113191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000695">
        <property type="protein sequence ID" value="GIY96722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050333">
        <property type="entry name" value="SLRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45712">
        <property type="entry name" value="AGAP008170-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45712:SF22">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY96722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="20908" checksum="644781311A90B68F" modified="2024-11-27" version="1">MQHSIISFDPTPYTSSFKGVSFDHSALIELLGVRVRRGWNWTPLEYLKSTTGTGLEIKLKGCGLKRLSSDFTKVADGSVKTVSISDSRLEMIGSGAFAEFGELNFFMLPRNRLRSIKRTDLPAEPKELLEIDLRNNRLQSLDADLFSEMPSLRIISLAGNPLRVLPEGTFSSVIGRTSLQGLSGNVVYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTJ7</accession>
    <name>A0AAV4XTJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_23331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000757">
        <property type="protein sequence ID" value="GIY97244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10854" checksum="662B8F79B0991B11" modified="2024-11-27" version="1">MHNVEKGRANHLVMKLFSWENNRKNSFPNMEVVSGGGKPEQWHPERFADCPALHFGWGYALLVMQGDRAEINKQSRTVAAPRETSSENAYPTNLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXY9</accession>
    <name>A0AAV4XXY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_426701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000998">
        <property type="protein sequence ID" value="GIY99050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10634" checksum="210AC3FA2CABB86B" modified="2024-11-27" version="1">MKHCESLLKLLFQLLKRCSIYSSLSIRSCSVDISTSGKAADCKTFNKGECSIAAGSYKPPVTVLQFRKSSISSGHLLKLQEGKLRWEEKSLFFSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y182</accession>
    <name>A0AAV4Y182_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_448581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001175">
        <property type="protein sequence ID" value="GIZ00574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y182"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="48" mass="5900" checksum="885FFD2A59CCF76E" modified="2024-11-27" version="1" fragment="single">MSKLGNVSVVIKIWMHIKAHVNELKYYKEKIEVYLILMIFHLYYLKQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3Q4</accession>
    <name>A0AAV4Y3Q4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_652401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018735">
        <property type="protein sequence ID" value="GIZ01887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831419" evidence="1">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="19274" checksum="1E86622010B9FD60" modified="2024-11-27" version="1">MTQLLSTQLMHTLLVRFLQVACSINTVLKKKKNLLNEVDFLIGLPVWNFFQVFFMRQFHEKVIPENIHLEFHEKVISENIHLEFHEKVISENIHLEFHEKVISEDIHLEFHEKVISEDIHLEFHEKVISEDIHLEFHEKVISEDIHLEFHEKSEDILRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y535</accession>
    <name>A0AAV4Y535_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_434241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001281">
        <property type="protein sequence ID" value="GIZ01315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y535"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="25335" checksum="0FEB39D1F723D6BD" modified="2024-11-27" version="1">MYEFYHFSIRQDWGFFNYKELFKEFWQICPSTLREVSEDDPNYFFLPELLPGEFSESCKDSSDDNDDIPVSLKEDIEDIPVALKKDAGGTAEETRKDAAVTSDESRKDAGATSDESRKDAGVTSDESRKDAGVTSDESRKDAGVISDESRKDAGVTSDESRKDAGVTSDESRKDAGVTSDESRNDTNYNPPNKGNVHIRMCILSRRKPFKYLFNNFKNITLIVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6P1</accession>
    <name>A0AAV4Y6P1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_614781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018890">
        <property type="protein sequence ID" value="GIZ03013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10490" checksum="4A1F906CBA8B409C" modified="2024-11-27" version="1">MTGFKKTAGPKFEIPLFRKALFPGQTPQNHDQSANHWQSSLSGRSLLMHYLPLPTTPSLQRLRRTNHGLPSNCCSRHHGRTINPGTGGTFNLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8X8</accession>
    <name>A0AAV4Y8X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_296421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001477">
        <property type="protein sequence ID" value="GIZ02589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="20610" checksum="5674ADBCFB083BCD" modified="2024-11-27" version="1">MCNSGFYGTKPAPFLTKEDSPSTPSGTGQKEQDVESSSPANCSSIKAFPNKSLPICKCIIGLSIYHPIPHTARSGYLSGKKLGLKLHQDLQEESSNKNKEKLLSFLWDFFKGVALHQEATHHPDKLRLEHQEATHHPDKLRLEVSKQPKTLGDDTGFIFSFLPKIWVTRGLAPLFLLIEFAVGVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAZ6</accession>
    <name>A0AAV4YAZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_78645_1</name>
        <name evidence="1" type="ORF">CEXT_648451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019056">
        <property type="protein sequence ID" value="GIZ04245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24393" checksum="4E979BCFD00FFD9D" modified="2024-11-27" version="1">MISGNNNYFKSSKSINELVLRLGQKTFEEIHIICQHSDAKHKLPPSNPFLIQADIKNTVRQCLHCYEFTHATRICGKKICPLCGVNHEGQCQAPEKCILCNGPHSATSKICPRHTLEQKILEFKCRNHLTIREARRLYAQSSKTHYSDAAKINTTAPNIEEIVNQRVESIVQNITIKMEQQTTLLVEIFQKTIENLVQYLVTVFHQTDLKKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCG3</accession>
    <name>A0AAV4YCG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001668">
        <property type="protein sequence ID" value="GIZ03910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="23169" checksum="01E96A33628BAFE9" modified="2024-11-27" version="1">MQPENDLLNQHYPILTYITPHIQDSEGIQPKIRAHKISRLNGFGNSYQQNHMQPQKRYTKPTLINSTLCYSTDTKFEGTLTRRTTSKIPYSFKSTQRTCNLRSRWYRLSTKNPTKSSRRGRSKQKAKCKNLEENLLALTKGERFEIQQKMLNKELSCFERYNKSIVHYGLSLDSRKRLGGVRFLAWQIKADFQWWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6X2</accession>
    <name>A0AAV4M6X2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_565591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001926">
        <property type="protein sequence ID" value="GIX68128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6X2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11945" checksum="0A46B3FD54489BEC" modified="2024-11-27" version="1">MNLIFLHRLIPEAFLNLIPKDFYAKIHVPKLEDRTGRKEGRKKGWMDGRKEGEMKGRKDRWNDGRRDKWNEGRREGRTEGRDKEGGLNLRKAGRNDARKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MB90</accession>
    <name>A0AAV4MB90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Abnormal spindle-like microcephaly-associated protein homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ASPM</name>
        <name evidence="5" type="ORF">CEXT_260921</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019514">
        <property type="protein sequence ID" value="GIX68681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MB90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX68681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="719" mass="86329" checksum="84A2A7594A96A3FA" modified="2024-11-27" version="1">MCYEKKSYLIQRVGFTKFQALFRAYKARKEFCEQKKAAVIIQRKFRSYIARRKYLIIKSSVLKIQNYYRGYRLMCLEKEKYLIQKIGFIELQAQFRAYKARKEFYMQKRAAISIQSTFKSYITRKRFLRLRLCAIKIQKYYRSYCLMSSDRRKYLIQKAGFTKLQACFQGFKVRRKFVEQKRAVVVMQSQFRSYINRKKFLILKSCAIKIQKFYRGYRLMCFQKQNYLIQKNGFLKLQAQFRAFKARKEFCMQKRSVVVIQNAFKCYIIKKKYFILKSSVVKIQRCYRGYKLMCLEKQKYLTMQTGFTKLQALCRGIIARSYFKILLKSTVIIQSHCKKMIVMNHYKKTKQSCIIIQQKYRAQQLMNKAVLKFQKIKRSIIIIQSAVRSYLVRKKYKNMKIAAIKIQSFARMVKCRKTYNYTCRQIIFIQQFYHAKYLMRLRKQSCIKIQSCWKSYKTRKELDRKIRAAEVIQRYFHLWREKKPHIDCAVNRQWYLKLKESTIFFQRQARIYLQRRTKSAILIQSYVRMWLTRLKYIRIKAAIKIQTLWRGYKVRQSVTDKNIIKSRQNIKAAPSSEHKSLGNRTKFALNLLLKNQNLATILHALQNLEVCTRLSPTCCERLKESGGISIILQAISVCNRSVPHQEIIKFSTDILLNLAKMFSFKSIKTVDSVWAEEAILTEGLRLMGVYRDKGLPIFTKCCTLFWIFCQDPKKKNPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MC08</accession>
    <name>A0AAV4MC08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_453941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002085">
        <property type="protein sequence ID" value="GIX69805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MC08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10516" checksum="9E88BBB30CEB3C69" modified="2024-11-27" version="1">MLAEMDSCFLLETKMIQDAAKDCISEIAPEVQVFTKDFVMAACENKDMYKKLDECFAEYEANVEFKKQMELRPEIVSCYSEILKNTSWKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGQ5</accession>
    <name>A0AAV4MGQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_257021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019711">
        <property type="protein sequence ID" value="GIX71030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043472757" evidence="1">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12238" checksum="E8B783E788E505C3" modified="2024-11-27" version="1">MNSMISIICLVVLACTAVSAGPLYPYASPYYGAYGAYGAYAPYVPESCSPMPLPYQLQFQQPPVAPAVPAAPVAPAVSAAALADYYAYARAASLSYLGYPYYGAYGAYGAYPYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHJ0</accession>
    <name>A0AAV4MHJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol-3-phosphate acyltransferase 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Gpam</name>
        <name evidence="3" type="ORF">CEXT_318031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019745">
        <property type="protein sequence ID" value="GIX71325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT/DHAPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563:SF23">
        <property type="entry name" value="BCDNA.GH07066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="GPAT/DHAPAT C-terminal" evidence="2">
        <location>
            <begin position="66"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX71325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="461" mass="53094" checksum="3D819E393DF2B0AD" modified="2024-11-27" version="1">MEESLRAGHSLEFFIEGGRSRTGKAVLPKAGLLSIVVDTLMSGRIKDAYIVPIAMSYEKLLDGNFISEQLGKPKEMESFSSAIKAIWRTLHSNYGTVRVDFCQPFSLREFLLAAEYSYNSPVRTLQPCLLPQNQCFFNHNMKSRRRSEYGTEIVSEDHRQLIKDCADYIVYTAFGSYSLMSTNILAFLLLTKHRKATTFDNLVNSMNWIRDEIAKRNKTLSFFGDSAELIRRATSLLGKNLVNLDVVKMEWYGNNNKKSIYYKPSVNLPEVLELQYYANAVLPAFLLESVIINAAYSLIPDNLGKCTNGLNHHLLRKDILKYSLELSSILQYEFIFFTSNVKTIKMNLLLYQIQKLDDFFAYGDQAELQQEIKLNTSNDKSTIQFLQCILTPFIESYFLAASVLYKLIDTEIEETTLLQDIKNLGYKKIHLGQICYLRFYQYKFSFDYDLYFKAGVFSLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MI41</accession>
    <name>A0AAV4MI41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_347801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002144">
        <property type="protein sequence ID" value="GIX70469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MI41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9048" checksum="1654A3C6C678E898" modified="2024-11-27" version="1">MARSLSVMSLKGLGAWVQYLSHSNARSQSYSWRIIFGRKGRPILRNTQPSMAEHYYLSGRDLLERWPGRLHRFRLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLN6</accession>
    <name>A0AAV4MLN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_744461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019929">
        <property type="protein sequence ID" value="GIX73240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030020">
        <property type="term" value="F:extracellular matrix structural constituent conferring tensile strength"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050149">
        <property type="entry name" value="Collagen_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023:SF1038">
        <property type="entry name" value="COLLAGEN ALPHA-1(XVII) CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="20701" checksum="951E637510B4062E" modified="2024-11-27" version="1">MKGMQGDKGERGEKGPGEPSGVERRSPLGMEGSKGNDGPPGQPGLEGPSGPKGAQGATGPKGDAGPSGPHGPPVRSPPGEGPQIPPEILFQRDYPYIRQRRSVSDELQADEPTKKKDEDEEKKEDEEGNFARQTSQHVCQHLHHAQRNRHDQKASWHEKESVKDMQGSLLGASRLSRRMVLGGPKFRHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWL1</accession>
    <name>A0AAV4MWL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_238261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002698">
        <property type="protein sequence ID" value="GIX76876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="21513" checksum="BBD3B70A43699134" modified="2024-11-27" version="1">MLKKHTICLGDEVPHNLKPTDRRRKIRKRATRWPPAAANHAPFNLPRFSKMCLPNHCDNVSTPFNCRPKPLKHVIVYVEKQKPKCPTIYTKDGLPQCARGNERENTHLRKAKRERQQSKSYDSHPNARLDPPFPTLISEASLFFYKRIVCKYIPEITLSHPIEKEETKIDTKRKNIVEEVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N572</accession>
    <name>A0AAV4N572_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_35571_1</name>
        <name evidence="4" type="ORF">CEXT_409541</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002990">
        <property type="protein sequence ID" value="GIX79975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N572"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="277"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX79975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="36129" checksum="1B1046ECFFC10390" modified="2024-11-27" version="1">MLISIKSLHEDLFTVEAEPSHTILHFKENIQKVKGDVYPAKYTKLMFAGKILLDNKRICDYGLKKRNLLYWLLKRLVPKLLPINGEAPDLSQIQFTTRERELILMAEHERLADLIVDLGFSREVVEEALRDNHNNVSRAIEAIVHSISASVNAADGRNYDAAIEFLEQIMQSVSPENSFLPTPERIADIFSEAVAECDTIAREQDDMIEANHEAITQNYEELEASGITDPHDIFENFFSNLAPISPEELPSAMFANGMSDLFNEAYNPSGLALAGNLSDSEHAAIERLKELGFAPHKVVEAYFTCGKDENAAAEYLFRQKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8J2</accession>
    <name>A0AAV4N8J2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_80811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020643">
        <property type="protein sequence ID" value="GIX80998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8J2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9101" checksum="FBFC8ED0BDB84C42" modified="2024-11-27" version="1">MRQTIHIHKVSLKYATKKKPFVCPRRLVSDKPPAEIINKSIPNHYFSLECIFKKRARVTAHFHARGAKQTLFQKERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8Q2</accession>
    <name>A0AAV4N8Q2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thyroglobulin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_241111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020657">
        <property type="protein sequence ID" value="GIX81187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8Q2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00191">
        <property type="entry name" value="TY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.10">
        <property type="entry name" value="Thyroglobulin type-1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051950">
        <property type="entry name" value="Dev_reg/Prot_inhib"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000716">
        <property type="entry name" value="Thyroglobulin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036857">
        <property type="entry name" value="Thyroglobulin_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12352:SF3">
        <property type="entry name" value="NIDOGEN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12352">
        <property type="entry name" value="SECRETED MODULAR CALCIUM-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00086">
        <property type="entry name" value="Thyroglobulin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00211">
        <property type="entry name" value="TY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57610">
        <property type="entry name" value="Thyroglobulin type-1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00484">
        <property type="entry name" value="THYROGLOBULIN_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51162">
        <property type="entry name" value="THYROGLOBULIN_1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Thyroglobulin type-1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Thyroglobulin type-1" evidence="6">
        <location>
            <begin position="44"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="78"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX81187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12053" checksum="7707B04587A04167" modified="2024-11-27" version="1">MKLIPKCKDNGDYAALQCYEHSHFCVCYDPKGHPASPILGTLSECGCYLRRKEKIDRNIENAYIPQCSETGAWVPKQCWDYNNSCWCVDKEGKQVGDIKAEGKGLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAH4</accession>
    <name>A0AAV4NAH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periostin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Postn_2</name>
        <name evidence="2" type="ORF">CEXT_131401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003144">
        <property type="protein sequence ID" value="GIX81586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10042" checksum="1E39B9C2F795CF02" modified="2024-11-27" version="1">MRLRKIRDLIESSQLQPYLQQAGPVTLFAPTDEAFSLSSVPSDPKRVRDFVLQHVVQGRVTPLDVRNDVILPSLRPRAAPSGSTCTRMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBN8</accession>
    <name>A0AAV4NBN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Pp2B-14D_0</name>
        <name evidence="1" type="ORF">CEXT_372791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003161">
        <property type="protein sequence ID" value="GIX81735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7725" checksum="682125E097BFCC9A" modified="2024-11-27" version="1">MSSNNVKGAPSDRIVKSVPFPPSHKLTISEVFDTKTDKVRVDVLKQHFVLEGRLEESCALKIINEGQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCY2</accession>
    <name>A0AAV4NCY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_516261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020660">
        <property type="protein sequence ID" value="GIX81269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14702" checksum="32ECD166559CAB9E" modified="2024-11-27" version="1">MGTLNLYTGMSFCWEGGGGEGGPSAMLLPSCPTTILNKYSQGIGVRNPSSTQPLVKAKSAVGIAQKPFNLQSIYYYQRDGPRGHRPEPKAGFPRKTGRIRTDVQGWRSSLFRMMDQASPSELIRNTFVWWDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEZ7</accession>
    <name>A0AAV4NEZ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_160031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003274">
        <property type="protein sequence ID" value="GIX82939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10659" checksum="A21C3F1D2833E5D7" modified="2024-11-27" version="1">MRLWKQWTDECHERTRKSGPSFPISGIHHHNLPDTQMYTSHSGTTAERQKLRNKHRRERSEVLADRRIFKTLPFIADEDAFQQLPTKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLC5</accession>
    <name>A0AAV4NLC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_619441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021073">
        <property type="protein sequence ID" value="GIX85585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10576" checksum="E2764943D89E7C2D" modified="2024-11-27" version="1">MYSGKLEIKEGRKEGRKEGRKEGRKEGRKEGRRKEGRKVGREDGRKEGRQDGWKGRMDGRTDRRREEGGRKDGRMEGRREGGRETFTHTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM87</accession>
    <name>A0AAV4NM87_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">slc20a1a</name>
        <name evidence="10" type="ORF">CEXT_577191</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003542">
        <property type="protein sequence ID" value="GIX85783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043775050" description="Phosphate transporter" evidence="9">
        <location>
            <begin position="18"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX85783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="504" mass="54789" checksum="E9A251386EC6CE1E" modified="2024-11-27" version="1">MELWIVILSFVFAFCMAFAIGGNDVGNSFGTSVGSKALSMTKACIIATICEMAGAVFMGYKVSNTVRKGIFEPEIFQELPMELSLGFFAVIIATALCTLFATMIRQPISGTHSMVGAVIGFVLVLNGYENIKWKMLGTIEKQDEVTRISWIVSPLLSGILSVIVFFLVKKLILSKENFIKRGYNSMPVFVWFTILINLFSIIHDGPSYLGFDILPIWGVLLISAIIGILFALGTYFIYVPFLKNSYSSTCDVERGEKNVKYIARDEVSSEVTSNDHNGSIIAIKEICVSVDEVEKKRIKVEKESGSSSVDVVPPAVTESAISSDSSPNDVDNDEDDHPQIAKIFSVLQILTAIFASFAHGANDVSNAVGPLIAVWSIYQTGNTNQNNEPPFWLMIYGGIGISFGLWILGKKVMHTIGERLTKINPSNGFCIELGAAVTVLFASKFGLPISTTHCKVGSVILVGLANSKGVSWKPVIEIICTWVLTVPISCAVSAAVMVLLKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMD5</accession>
    <name>A0AAV4NMD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element tc3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RF55_24064</name>
        <name evidence="1" type="ORF">CEXT_440491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020992">
        <property type="protein sequence ID" value="GIX84689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326:SF1">
        <property type="entry name" value="HTH PSQ-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326">
        <property type="entry name" value="TRANSPOSABLE ELEMENT TC3 TRANSPOSASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17133" checksum="64128345D71EA5F7" modified="2024-11-27" version="1">MRDSKGPITSSALKKVMKKFEATGSLASRQRSGHLTTAAAVATTVEQTVQSMSAVAAHGECSAREVSRQTGVSYGSVWKALRITLKWYPYKLQHKQELKPPDFDSRRGFANLEARLRNIRVVLDPYKTLNADLHLDAFHYKDDMISLHPSVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUX4</accession>
    <name>A0AAV4NUX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_352551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021336">
        <property type="protein sequence ID" value="GIX88561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13198" checksum="17AAB18A635C16EA" modified="2024-11-27" version="1">MAANFGNVRSSKESPNPLPVDEFHSSSHENRRLLVRGERNETKRSSFSKSQELLLTLMYAKGAPLTTTMGYFYHPRVSPPVSGIPLLKCEDPFMVPNSGIILMESAQPTSHSAYPFVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NV22</accession>
    <name>A0AAV4NV22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor 1-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_551881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003696">
        <property type="protein sequence ID" value="GIX87605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NV22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000003">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000090">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX87605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="330" mass="36636" checksum="702182C02723F5B1" modified="2024-11-27" version="1" fragment="single">MPKDKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDITLWKFETSKYYVTVIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAYTLGVKQMIVGVNKMDTTEPPFSESRFEEIKKEVSAYIKKIGYNPATVPFVPISGWNGDNMLEPSTNMSWYKGWNIERKTSKHEGKTLLQALDVMEPPSRPLDKPLRLPLQDVYKIGVETGILKPGTVVTFAPANITTEVKSVEMHHESLTEAVPGDNVGFNVKNVSVKELRRGYVCGDSKDTPPKSTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYB4</accession>
    <name>A0AAV4NYB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_161411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021449">
        <property type="protein sequence ID" value="GIX89761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15795" checksum="EF9F26509971EB90" modified="2024-11-27" version="1">MAEGMEDQKRIIEEKDKLIKRQFIRIEELESELTALKEERDALLCDVNKLRFELEMSELKRLKDVRATPPSSFQSAITLLSLRHVETGNLILSGNCSPNFQVEKCLSKCYIHVTLESGLGMVVNWREFLRIFLRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2H7</accession>
    <name>A0AAV4P2H7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lig_chan-Glu_bd domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">AVEN_76534_2</name>
        <name evidence="12" type="ORF">CEXT_67041</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003968">
        <property type="protein sequence ID" value="GIX90758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2H7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="11">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX90758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12373" checksum="D73B36CF97342B74" modified="2024-11-27" version="1">MPHIVKSVAKWMNITLSFIKEPEDNYGSWVNNTWNGMVGMLYRNEVDLILNPIMPKDKILEFAYFTNPVTVDAYTILSGKESVDPYDLSSDYNRPDVYCNIQKCDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4B5</accession>
    <name>A0AAV4P4B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_222471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003907">
        <property type="protein sequence ID" value="GIX90027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13767" checksum="7BE1C773AB5EED9F" modified="2024-11-27" version="1">MGSSNPQLNSILRARSKQDLSITAAEDRLRPGLAFNFFALSIEKVFAHFLVVVPKVIVSREGPSTMLLERKLFGRGECGTNNAWPKGKWLHVKTIRRPLNLVVVEDSQWENSSQLSLVHLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJQ3</accession>
    <name>A0AAV4PJQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_269781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004610">
        <property type="protein sequence ID" value="GIX96119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="7991" checksum="AF0FA1AE6F2AE997" modified="2024-11-27" version="1">MKVVHLQHALQNVCDRCPVNGGGGHPSTATEHRKFSFVTTGPCCGHRILSPGQWSAGSSTPLGTADPPKGTEAPEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPW8</accession>
    <name>A0AAV4PPW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_193451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004840">
        <property type="protein sequence ID" value="GIX97955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11374" checksum="374F984F8CFE2F56" modified="2024-11-27" version="1">MQTSTSMINGAQVMRRCCSLRILHRSFSGQERSHAVLTKADPGVEWEELGREKELCWDFFSSHSNRLRHIFAIDFAVSIKWAFFRQGRMLLLNAFALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PVU1</accession>
    <name>A0AAV4PVU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_554701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005162">
        <property type="protein sequence ID" value="GIY00294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PVU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11507" checksum="BD8AC4B8714464F5" modified="2024-11-27" version="1">MMHHVPYLLGDNIASVLSKTLTLMSSAYNERCYRSNDTCCYKKELINGNSPPKKSSEHSRKYFRILSGEITEILLYIKSDIRYVDKSIEQPRQSLFDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXE4</accession>
    <name>A0AAV4PXE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNase H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_40277_1</name>
        <name evidence="1" type="ORF">CEXT_543251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005370">
        <property type="protein sequence ID" value="GIY01815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11074" checksum="453764C79C5BD6E8" modified="2024-11-27" version="1">MQILLDFNNLVNQEILPLEREQPPWHNDKIKVIDDLDRFPRPTTLPATYLQLFYSHRQAFSQYKEIYTDGSKSNNHVPSAVVIENEMITQCLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q150</accession>
    <name>A0AAV4Q150_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Meckelin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_178561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005534">
        <property type="protein sequence ID" value="GIY03049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q150"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019170">
        <property type="entry name" value="Meckelin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21274">
        <property type="entry name" value="MECKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21274:SF0">
        <property type="entry name" value="MECKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09773">
        <property type="entry name" value="Meckelin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="39057" checksum="9B3DC6DDA4C521D2" modified="2024-11-27" version="1">MAGVSIWRTYYAANEWAEIQSGAKTSLYIQLFGVLFILNEKVLGFESSTLAALKLNIPPVDVHKYVPYSTCCRFGLGVLVYMFVAVLQIIVRKGLYERFVEDKLQQYVDLCSVSNVSVFILVTKRFGYYIHGRSTHGKADVNMKEMHEFLRKEEEDLCGHRGLLPDTDQQTFQILLPSGVHDQFLRLLVPLTSYTQAADRMQGVGGRLAKVDIDRVANTHYMLNKFLSGFIDHSFKDLDYIVKDRVMLEFLLDIECYEVADRGYFYNDDGRSFSSVLFYGNESILLIFDVLLFSIIDIAFSDYVLSMILTFILAKAIQGIRRSAGRRNLVRKALVDERFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3K9</accession>
    <name>A0AAV4Q3K9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_757411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005599">
        <property type="protein sequence ID" value="GIY03580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3K9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.960.10">
        <property type="entry name" value="VSR Endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8487" checksum="0F6BBBA3687BCE54" modified="2024-11-27" version="1">MGIVSRRIQFISFMGCFYHGCPICYDPDSVHPLKGISMATVKEKTDMTSTVLRSEGFQVVELWEHEFAEQKTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q562</accession>
    <name>A0AAV4Q562_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_549621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005588">
        <property type="protein sequence ID" value="GIY03507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q562"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13866" checksum="90639113BA020CDF" modified="2024-11-27" version="1">MAGHSAPGHKLPAWLAHPFPGCSSLPSTASLLKCRLVSASINPFLTSMDKMKNLSNHPTRRPLVEWVRKTLAETLNEKWHFCSGNRSEMSEAIYSQPSSFRRGKKKGLQDEKRGDWEINKYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5Z0</accession>
    <name>A0AAV4Q5Z0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_21331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005750">
        <property type="protein sequence ID" value="GIY04774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15259" checksum="187A40133117B485" modified="2024-11-27" version="1">MGSGNLSKYTEFLFTAGLFQKACQLSLFVALQGTLSSSRLGRVFPTLLNQPLCVSCKLWHSGAPDRAQSTEMASLSSLLWLQKINNKAAVFYTIKNIFGKEQHPDEDSTGHTTECKLKHNHMLAASSVPPLEMSIDKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7L7</accession>
    <name>A0AAV4Q7L7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_83501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005793">
        <property type="protein sequence ID" value="GIY05050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11577" checksum="767038985FC5E0EE" modified="2024-11-27" version="1">MEDSQVNLIFENAATLFGTVFHILEHLSKKKKIIHAVFAANNSDPRQISAAILGRHKQHAKSTNVAANITRNVSGKKKENKCFLLMIFFSLSVTVTKLRRKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QX70</accession>
    <name>A0AAV4QX70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_788791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006865">
        <property type="protein sequence ID" value="GIY12909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QX70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12158" checksum="9BFA3149415C2D28" modified="2024-11-27" version="1">MTSLLNKKASITERDAKVKILDLKVELKRPLVISATSMQKESSRSMSTSDILSAFSTGLELHINLELPYLFLLQGRQYQPRQDAEGYVGRYIASRLPPATGSFFFAFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RA83</accession>
    <name>A0AAV4RA83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_319321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007454">
        <property type="protein sequence ID" value="GIY17037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RA83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9314" checksum="A963712324B0F3A5" modified="2024-11-27" version="1">MAKSLNTSSFVLWNLNASREMSGAETFFCRANPRRVKIDLTRVYIVIQMKRIYRDMFLMLTEGLPEEWTEGRMLLELPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RI54</accession>
    <name>A0AAV4RI54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_190221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007804">
        <property type="protein sequence ID" value="GIY19895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RI54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="13439" checksum="39F337B0786AE7FC" modified="2024-11-27" version="1">MFRGCQFRDPHQQPTAAAAATSALSPNNRNPTCTRRIFHHIPHPCPAPRPLPPTLLGGGGGQASGSATTPPNRRSRRRKSLLYQVLMSPLGKKSGSTNTLNTVASGNSSSNHRSGGSVSKFLTQVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJF1</accession>
    <name>A0AAV4RJF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_569601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007868">
        <property type="protein sequence ID" value="GIY20360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10882" checksum="ABE28355FDA866A7" modified="2024-11-27" version="1">MLRQQARPPQVKVAYLSKTCPILNTAGRTVMNRKKKNQQKESVLLFETCGLRHCDRQEALSDRASIKMESRLSAPRLSCQPRGAIISAPFLSLISGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLC3</accession>
    <name>A0AAV4RLC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008127">
        <property type="protein sequence ID" value="GIY22270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="33635" checksum="94EA172E34726E48" modified="2024-11-27" version="1">MAQLFIPGQTLRDSPLKIELFYFGERFKPKKDEYPSERFRVFKRRSNSSQGGTIHLHPFPTHLGLGTPHQERNGTSISIWPHTFISNTIYFVPLGLKRHNYPFLDKILRDFFPPKNRELFYFGERFKPKKDEYSSERFRVFKRTSNSSPGETIHFHPCPPHWGLELFYFGERFKPKKDEYPSEWFRFLSAVQFRSPGDFFNPKNRELFYFGERFKPKKDEYPFERIRVFKRRRIRPPGETIPSPPLPHPLGSRYTPTKRETGQLFQFGPIPSYRIPFILCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQ43</accession>
    <name>A0AAV4RQ43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_689251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008294">
        <property type="protein sequence ID" value="GIY23590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQ43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13383" checksum="DADFC3BDB30DE44D" modified="2024-11-27" version="1">MDRENGIKESFRYAGVRKRDLLKQRVLKLAIVKWSPPQSTAFKKWNSSPLILAIRKTTHAEYPFFPSRSHPILIYFFLERFFLSCYLCSVSVSTKVPIVFCYSRNNSPHCGFSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQF2</accession>
    <name>A0AAV4RQF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_632531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008303">
        <property type="protein sequence ID" value="GIY23710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="253" mass="30540" checksum="8A3A418182EE7692" modified="2024-11-27" version="1">MLIQLDIPTTAADSDWIGHSDNLNTDSDWTFRQLTTDLDWTFRQLTTDSDWTFRQLTTDLDWTFRQLTTDSDWTFRQLNTDSDWTFRQSTDLDEHSDNADSAFRHFQQLLADSDWVFRQLTTDLDWTFRQLTTDLDWVFRQLTTDSDWTFRQLTTDLDWTFRQLTTDSDWTFRQLNTDSDWTFRQLTTDSDWTFRQLNADSDWTFRQLTTDSDWTIRQLNTDSDWTFRQLTTDSDWTIRQLNTDLNKIGHSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQS0</accession>
    <name>A0AAV4RQS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_32421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008226">
        <property type="protein sequence ID" value="GIY23034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7606" checksum="DAEEE19116C43231" modified="2024-11-27" version="1">MGFIVVPSLMLRRERSLTASTQLKPCGNPSREWKQALFLPRCLSHSSEASIRAAAVAACWRERETICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RS35</accession>
    <name>A0AAV4RS35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Diuretic hormone receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_105121</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008496">
        <property type="protein sequence ID" value="GIY25133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RS35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017046">
        <property type="term" value="F:peptide hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050332">
        <property type="entry name" value="GPCR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620:SF15">
        <property type="entry name" value="DIURETIC HORMONE 44 RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620">
        <property type="entry name" value="PDF RECEPTOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111418">
        <property type="entry name" value="Hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="9">
        <location>
            <begin position="62"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY25133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="233" mass="27201" checksum="25601A8A25526CC4" modified="2024-11-27" version="1">MSRPSQPKNILEDVRIHDRIGNASRECLQNATWSSWSNYRSCKPLKIPEDEYLQVLWDMRGAVTVYYVGYGLSLIALTLALWIFMYFKDLRCLRNTIHANLMFTYLLLDITWILTAKLQTSQNYVSSRIACFLTIFLTYLMGTNFFWMFVEGLYLFILVVKTFTVDNVKLYVYTTIGWVIPAIIAATWAGVKGHFGSTIQDVLEPQGERERKRDYEKNLRHVYVGKSRKFSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUE2</accession>
    <name>A0AAV4RUE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_243661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008485">
        <property type="protein sequence ID" value="GIY25060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="291" mass="32860" checksum="CFF9C52A7ACF1E5C" modified="2024-11-27" version="1">MNTREPRPEEKTRQVQIPKGIPVEPSGGLYPHQGQKFNRRNGKVIYDAVKTRIEINNLMNKLQKCKPDSPTYESTRTKPKSSEQLENRLIRVNLKVKQIPEHMGVLEEIFSTFGIKTSDLEEAIPTPLKETAPPTDQVDDDIHKYKSDLKVVLKDNTTYPNSSEELQALLIAKGIIPNSSTEVAPNLITPTSEEVIMDTSEESQNGPSPTEEPYHIPPKRLTCRDQTQDPKTQGPKIKNQYSPLIQMDTENSTAMPERKKQMPPFFITPNASWPETCKVLTSTVESLNISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWN3</accession>
    <name>A0AAV4RWN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ANF_receptor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_113206_1</name>
        <name evidence="7" type="ORF">CEXT_715731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008493">
        <property type="protein sequence ID" value="GIY25119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043517562" evidence="5">
        <location>
            <begin position="27"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Receptor ligand binding region" evidence="6">
        <location>
            <begin position="55"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY25119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14971" checksum="05EF9AADEEB784EB" modified="2024-11-27" version="1">MHTLLTLVNIYITLCILESAPRLVKAKNYTMGYLTGSQRRPGNKGYPRPGLTISGAISLAVHEINKYHPLRDNHTLTFTVAETYGEESESIHQTAVLWTQDIAVYIGPQETCVHEARMAASFDLPMISYVSTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXX8</accession>
    <name>A0AAV4RXX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_506561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008694">
        <property type="protein sequence ID" value="GIY26524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9190" checksum="7EF087AD58191953" modified="2024-11-27" version="1">MLACFPDMDCIENAFATLQSATLVNYKPDRYIVSIQTPPMTVVLLSPRQYYLEHAQYCGVTRWDLKGEFSKLGCLTIGNTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6F6</accession>
    <name>A0AAV4S6F6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_443581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009172">
        <property type="protein sequence ID" value="GIY30083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6F6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="235" mass="26149" checksum="578D0E46791D7C63" modified="2024-11-27" version="1">MGVGVCTHGGQLWVIGGMVQNKGRKIDLIKDGKRYDPDKQSSVRNLSVEVGEEGDSNTSCSSGLVQRFVSRDASEVSGFEQAECRNSSAEGGVIRNELFEWARSKIHVPRCIGGQWNDWLLYYSREKPSLSTVERAVGGIANGLSVCASALWERWLVGILWNYDIPTPPSLALSSGRWCGKRLYVIGDLLRGHRHLLRGAQQPDDALVYKDVKRKCADLRSHAQSPSFCRQRNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SF07</accession>
    <name>A0AAV4SF07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_342971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009425">
        <property type="protein sequence ID" value="GIY31776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SF07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10161" checksum="59F629CC70E8C62A" modified="2024-11-27" version="1">MRQKCLLPFLPRRLFQYPPALKPKTRIEETGARRAFQEIKTKGREKSILESPLAANKDGPTPSLPARQVNLLAPGLRPMGEPEKNTFHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFA7</accession>
    <name>A0AAV4SFA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activating transcription factor 7-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Atf7ip</name>
        <name evidence="2" type="ORF">CEXT_516451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009594">
        <property type="protein sequence ID" value="GIY33128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026085">
        <property type="entry name" value="ATF7-int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056565">
        <property type="entry name" value="Fn3_ATF7IP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23210">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23210:SF26">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16794">
        <property type="entry name" value="fn3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activating transcription factor 7-interacting protein Fn3" evidence="1">
        <location>
            <begin position="104"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="234" mass="26876" checksum="DD2A53BA587FA33F" modified="2024-11-27" version="1">MITSDATRSTDLPVCSSVGFSNKWKEGLKEIAPSFVLLSASTIKKTPVSFFHVGYFKPKKSSATNSKFGLVSGLRRKADDKLTHPLPFPPKLLPKGYKKLRSILPPKPYLTAFVQNDDSFFLRWNMPRRTRLLNYRKIKYFEIFNYVSSNEPISSLEWEMLRKEDAKELPMACALRDFDEGCKYFFAIRAIDVHDRSGNFSNPISIEYEHTNIEHTEFPKEAKQVSSKLPPPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGI9</accession>
    <name>A0AAV4SGI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Substance-K receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TACR2</name>
        <name evidence="11" type="ORF">CEXT_220831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009653">
        <property type="protein sequence ID" value="GIY33523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042923">
        <property type="term" value="F:neuropeptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008188">
        <property type="term" value="F:neuropeptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235:SF29">
        <property type="entry name" value="GH23382P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235">
        <property type="entry name" value="NEUROPEPTIDE Y RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY33523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="224" mass="25581" checksum="7D68B69872650D6D" modified="2024-11-27" version="1">MSRWITLIAVITQYVLPLTITGVLYYLIIVQVWSRDAVGVVTENQRISQARAKKKTIKMLVLVVILFAICWLPLNTFNIMREFNVTILMQKSVTHSTVFFICHWLAMSSVCYNPFIYCWLNDNFRSGALRCLLCVKNASCHINESLLSTKASRPSSNAPTMQSVDCGQDSNLDSAINNASRNAIQRSNMMPYTDQSRCRQKSHEFDIPLRYLPTKNSQSIVEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGL3</accession>
    <name>A0AAV4SGL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MAP1LC3A</name>
        <name evidence="12" type="ORF">CEXT_133701</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009489">
        <property type="protein sequence ID" value="GIY32301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16129">
        <property type="entry name" value="Ubl_ATG8_MAP1LC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000149">
        <property type="entry name" value="microtubule-associated proteins 1A/1B light chain 3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY32301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14530" checksum="79A8992132413D09" modified="2024-11-27" version="1">MSETKSFKERRSFSQRKRDVEQIREQHPNKIPVIIERYYGERLLPLLDRSKFLVPDHITVGELSNIIRRRLQLHPNQAFFLLVNQRSMASVSMTMSDLYSREKDEDGFLYVVFASQEGFGFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQC7</accession>
    <name>A0AAV4SQC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_13941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009908">
        <property type="protein sequence ID" value="GIY35421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY35421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16999" checksum="3206A3BB3216DED7" modified="2024-11-27" version="1">MEALNNFEDFKSTDNCIADINQTKEIQPELCKRVKFSPRFERMLLCYSKTHYNRSNTEIGDSRTKSPSKIPQLIKNKCYAIGPDCLKVIKPEHTVSEGKLSCDSSSSSNCGSLPQSHSHLKINETDSQTSLEYSEEEQNESEIMKRQLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUH5</accession>
    <name>A0AAV4SUH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein XRP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RP2</name>
        <name evidence="3" type="ORF">CEXT_601581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010089">
        <property type="protein sequence ID" value="GIY36801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990075">
        <property type="term" value="C:periciliary membrane compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039093">
        <property type="entry name" value="XRP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15440:SF0">
        <property type="entry name" value="PROTEIN XRP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15440">
        <property type="entry name" value="XRP2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY36801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9206" checksum="9FA12B39E7393AFC" modified="2024-11-27" version="1">MTWLLPSYEKENKEDVNPKDFIIENAKDETIVRLPNSVKGQQFIIQNCENSNIYIYDHINTITVDDCNGCNVFIGPTKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3X5</accession>
    <name>A0AAV4T3X5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Haspin</name>
        <name evidence="1" type="ORF">CEXT_167091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010581">
        <property type="protein sequence ID" value="GIY40237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072354">
        <property type="term" value="F:histone H3T3 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="50791" checksum="58A44AFFE0C83A69" modified="2024-11-27" version="1">MVLKGEDGEGFHKSSRSLNFPSNVVSFFSAWANFFAKTFRESWLFLSCDEFVLLFWKRDYPCCDISAEITPELEKVFKFCNVKSNVKFAEALLFWKQRSARKISEGSYGEIYQFKHVDGTDRVFKCVPVNGQHPMSSYLEYSSRNVSNRHSLLEIRKYKFRNSFHSICLVRDHFPECLVRAWWDYRSSLERLKDPAEHHQPDQYPESQLYLTIESSFCGEPLTMRMLQNAWLGVSIMSQITAALAVAEAAYNFEHRDIHLGNILVRSTNAVSLKYTIHNHHFSIETVGYHVFIIDFTLSRIYCDQNVYCVGLDEIARQSNENKEVSDCIWLNHKNIYKIMAEYSKREWDKYMPITNIIWLKYMNENILDYLQKNNPQFMKLVPPNNEHNQMKAINLLRKWNDCILQHKSAMDLLNNTILEITLLFACMNDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4M5</accession>
    <name>A0AAV4T4M5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_202241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010593">
        <property type="protein sequence ID" value="GIY40291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4M5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="301" mass="34631" checksum="86F1E5C301D580DB" modified="2024-11-27" version="1">MSAGPSKKIEPSMESEENEEKIVNELFSYFEFRDHDRLKDEESNTDRTKNISKKTKDGGENKRLKTSPETEGLLESKRQKTCQEKDDESPHPESCNKCGVASTSPGKPALEEELRSILKKCLPTIVCECMHLIHYATLSEELAFAINAMSTVRHLNGLEFRLFKYNHSIGRLVLPHLDAFQTAFEAVWRRCNAAIEKYCAANWYHKNLNYKKFQLLLVCGTKRFRLHLREIETCQGTHLIYFSVLLCHVGVLMEKRGIDRATYFIPLALSRLITQLFYGGLFRDWAEFAKTAEKISKKIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TA38</accession>
    <name>A0AAV4TA38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_170721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010911">
        <property type="protein sequence ID" value="GIY42940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TA38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18905" checksum="38CEAC6D91476F6E" modified="2024-11-27" version="1">MEIITALCSSRLPVKLLYLNRVVEQPIKTKRDPCYYHGVNRAALYSFSAFVRANLRQLSRRHLVEEILVADDVGDIYKSPSAESYLFFCCAALLSAWSGCWQYCVFIDNGWCRSQETKSIFMSEVVVKLVTFPGVAGTTQEPLGGFSLPREHNRRHQLPSSKSHFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFM3</accession>
    <name>A0AAV4TFM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Synaptic vesicle membrane protein VAT-1 homolog-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Vat1l</name>
        <name evidence="5" type="ORF">CEXT_322131</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011152">
        <property type="protein sequence ID" value="GIY44504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08275">
        <property type="entry name" value="MDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052100">
        <property type="entry name" value="SV-ATPase_mito-regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44054">
        <property type="entry name" value="SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44054:SF2">
        <property type="entry name" value="SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="55"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="379"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="386"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY44504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="436" mass="48220" checksum="3FF716F20C9A994A" modified="2024-11-27" version="1">MEEENKAATNEVVEEKNDDSSKEKTENDVKEAVEATEEQTPPAKEMKCVVLSSFGGLKSVKIQNKPEPTPGEGEVLIRVKACGLNFLDVMLRQGVIDCPPKLPVVMGYECAGEVEAIGEGVPDVQVGDRVAALTDCKSWAELVVVNTNYVYKLPQEMTFQDAAAMLMNFVVAYGLVFDTACIRENQTILIHSAGGGVGLAVAQLLKTIPNVTLIGTASKHKHDAIKNYYSHLIERGVDYVQEVKKLAPSGVDIVLDCLCGEDSNKGYSLLKPMGRYILYGNSNIVTGETKSIFSVAKSWWQVDKLKPMKLFDENRSVSGFHLRHLLYKQNGHDYVRSAVEKIFKLWLDGQIKPIIDSTYAFEGIPEAMQQLHERKNVGKITLDPAMEPKPKPVVESKKRKDSVKADKKNDGKAQKTDETQKNEEKTEDKDAPADAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TH68</accession>
    <name>A0AAV4TH68_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_530081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011276">
        <property type="protein sequence ID" value="GIY45484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TH68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043966231" description="Secreted protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY45484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="15485" checksum="13495675DF537FE3" modified="2024-11-27" version="1">MSRIRILKNLIILCLVFFTLHFLSIPGESSEHSQHRRRHRHRVPKYHLRFPDHLFVTSSQTHHKKTRLQMDAGPEHSHLHPLHRSQLLPLHVNTGADHRSNRTRSCTPVVRQVHLPERDQRPVRGPNIRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TM18</accession>
    <name>A0AAV4TM18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Troponin T, skeletal muscle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">up</name>
        <name evidence="5" type="ORF">CEXT_132551</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the troponin T family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011428">
        <property type="protein sequence ID" value="GIY46496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TM18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005861">
        <property type="term" value="C:troponin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005523">
        <property type="term" value="F:tropomyosin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006936">
        <property type="term" value="P:muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006937">
        <property type="term" value="P:regulation of muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.350:FF:000003">
        <property type="entry name" value="Troponin T isoform 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027707">
        <property type="entry name" value="TNNT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001978">
        <property type="entry name" value="Troponin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038077">
        <property type="entry name" value="Troponin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11521">
        <property type="entry name" value="TROPONIN T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11521:SF1">
        <property type="entry name" value="TROPONIN T, SKELETAL MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00992">
        <property type="entry name" value="Troponin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90250">
        <property type="entry name" value="Troponin coil-coiled subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY46496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="405" mass="48034" checksum="32FCF34E5298610F" modified="2024-11-27" version="1">MADDEKEYSEEEEEEEEEGPAVGEKDEPKPRQEISEEPKAEISEAELAMEKMRKKKEEEEAMWAEYMEQRKKQRAKEEDELKKLKERQIKKKRKKKRRREEITSIKKATRSSKGQRNGREKAREAEAKKKRLEEAEKKRQAMQDALQRNKIQEPVTPNFVITKRNEDGSVVPGIDKFPSSLYMKAEMAKTKEQLAEDKKMALAFRVKPLQIENLSVTELKQKAQQLWDSIVRLESEKYDLEERRKRQEYDLKELSERQRQINRSKALKKGLDPEALSGKYPPMINVASKYERRLDRRNFTDKKSLFEGGYVSQLESMTVTEWENRMKNFKDRPSKLLKWDPSGPKNKEKPEHTEIIEEEDLGEPPYMASQDDNEPQPDDNQNNNEEEEEEEEEEGEEEEEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TR33</accession>
    <name>A0AAV4TR33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_72811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011602">
        <property type="protein sequence ID" value="GIY47619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TR33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11216" checksum="C01BF2BD81B0246A" modified="2024-11-27" version="1">MVLFRKFRKQEDQKGFMDQDELSENVVGTIEMPKHKQSKGLSRAQLPLLQEHVQAIPYSLAQFYWISHQFRNKVQPGVAIVDMVSNRTNMVSLFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TTA7</accession>
    <name>A0AAV4TTA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_159801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011713">
        <property type="protein sequence ID" value="GIY48414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TTA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="22446" checksum="7A50AC79535D837F" modified="2024-11-27" version="1">MKLCRSPNKQREMQGDREQLNGTRTSFPVICSSVNGISFPHRRTDQWMFVFPPRSQPLITAQDEQREKEMAHNLHNYIWSLEFRVICSSVNGISIPHRRTDQWMFVFPPRSQSLITEQDEQRKKRRRTCIIPSGVWNSESIHERTTDLRNEIVQTSEHAERDGGREGEQLNGTRTSFPVIRSSVNGISFPHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U211</accession>
    <name>A0AAV4U211_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_271361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012158">
        <property type="protein sequence ID" value="GIY51763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U211"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14786" checksum="20B5D38BD93F2037" modified="2024-11-27" version="1">MSLKTYPESLRLVEKAPCCVADPSNIFGPSTISLLWFSKSVYELLATKEPANLLCAHMNCLLLRLTDKACERYCRRWWPLSTRREPNLLKAYFENIDPPFYVLPAFGPLSDKHLVKILKILISRVDNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U368</accession>
    <name>A0AAV4U368_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ubiquitin-related modifier</fullName>
            <shortName evidence="6">SUMO</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">smo-1</name>
        <name evidence="8" type="ORF">CEXT_279991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ubiquitin family. SUMO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012207">
        <property type="protein sequence ID" value="GIY52183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U368"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd16114">
        <property type="entry name" value="Ubl_SUMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000280">
        <property type="entry name" value="Small ubiquitin-related modifier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046332">
        <property type="entry name" value="SUMO1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="17"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY52183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10943" checksum="ADA92B96E839D20F" modified="2024-11-27" version="1">MSDQVQEQKAEGDSGSEYIKLKVVGQDSNEIHFRVKMTTQMGKLKKSYSERVGVPVTSLRFLFDGRRINDDETPKQLEMENDDVIEVYQEQTGGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UC29</accession>
    <name>A0AAV4UC29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_219671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012629">
        <property type="protein sequence ID" value="GIY55303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UC29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9752" checksum="8A3DF648CB13DB2D" modified="2024-11-27" version="1" fragment="single">QSRNFLSASPQAHDDFLTFLINHARIVNSKAESFFSPPPQAHDDFFLTFLIYHARLLIEKQKLSSPPHQAHDDFLTFLIYHARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZX6</accession>
    <name>A0AAV4UZX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_108881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013706">
        <property type="protein sequence ID" value="GIY63153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9739" checksum="AEFBF9029A989B81" modified="2024-11-27" version="1" fragment="single">TEKGCEHSSVRKDFIGVYRRGRKTPSSRVELSCRPADRRFRLECRQFVNEWSRQPFLEVMFGHIRVQQQKSLIRCYDSGGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V115</accession>
    <name>A0AAV4V115_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_210947_1</name>
        <name evidence="1" type="ORF">CEXT_267991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013802">
        <property type="protein sequence ID" value="GIY63910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V115"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8699" checksum="57ED030D2AABEBDC" modified="2024-11-27" version="1">MYRNSSCISSAVAHHFRNLMRQNAGTIKQLWQKNGILRICSLGGGAPSDVVALVKVLEQDLGYRMSGDIHVTVVDIDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1Q3</accession>
    <name>A0AAV4V1Q3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLK4</name>
        <name evidence="3" type="ORF">CEXT_613031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013838">
        <property type="protein sequence ID" value="GIY64162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1Q3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047108">
        <property type="entry name" value="Plk4-like_POLO_box_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033699">
        <property type="entry name" value="POLO_box_Plk4_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033698">
        <property type="entry name" value="POLO_box_Plk4_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046437">
        <property type="entry name" value="Ser_Thr-PK_POLO_box_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18190">
        <property type="entry name" value="Plk4_PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18409">
        <property type="entry name" value="Plk4_PB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51984">
        <property type="entry name" value="CPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51985">
        <property type="entry name" value="CPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cryptic POLO box 1 (CPB1)" evidence="1">
        <location>
            <begin position="260"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Cryptic POLO box 2 (CPB2)" evidence="2">
        <location>
            <begin position="375"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY64162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="424" mass="48383" checksum="49E69FB88D79CC8A" modified="2024-11-27" version="1">MSVQRPGSCLRICSPRTPGRESRLMLCLSPNFLRNMKRSTSYLKLLFKKGSYYKDSGHGSWSGKESHHKSQGNYDSGFNSNHSDLNLCIERKCRSDTRFAKSPLLKECNGEKIICLQMYMSFFLVVYPPERSLTLDRLKGRIQALPSLKNSLRKDYVSAENIYGQKTSDSCRIQGRICGDNLVVTKDEHDHCQSHRTNPYMSEKCTDFNCKFNHSNGENNALQLACSHSDLCAKCSHATSCCCQKSHQKNSHPEKLDSNSLEQTTLPLNAARLKPRKHRIKNDAVVSISAERQVIVELLKTRNKQQFVSDVCIISTDGMEIKLYKPKKIALQDCPPPLPTNSKEIKFYNFTNFPKTHWKMYLIAKTFVDILRARTPKLTFFGKNAKCIMMENSPDPDFKMDFYDGGSVKKEERKSPLLTSMAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2S4</accession>
    <name>A0AAV4V2S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_790971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013843">
        <property type="protein sequence ID" value="GIY64199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9762" checksum="4069C53E7AF5C02D" modified="2024-11-27" version="1">MYRGTEKMDGQNTELFSSETVPSRTDDISSGFVFCQNVFLTWCTPHPLLFRTFLLVCSVRQPRWEIRNLNVPQESDVKVWNDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7Q6</accession>
    <name>A0AAV4V7Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger FYVE domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZFYVE1</name>
        <name evidence="6" type="ORF">CEXT_616581</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014064">
        <property type="protein sequence ID" value="GIY66043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005547">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043325">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15734">
        <property type="entry name" value="FYVE_ZFYV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042427">
        <property type="entry name" value="ZFYV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46624">
        <property type="entry name" value="AGAP002036-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46624:SF4">
        <property type="entry name" value="FYVE-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="123"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY66043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20352" checksum="2CB4CF7A9EDEEBBF" modified="2024-11-27" version="1">MANSSIKHCGHCLKLFDDLEQKHHCRMCGGGFCEACASDTKVVPTWGSSPVRVCKKCFQNDCEKGFVAENDVPNVQNLHNPPEVTVRKIGEAVHTTLETVASVVSYPLGYIKDSARPTYWVPDHELFNCYVCKVEFGPKVSKHHCRACGEGVCMDCSKSRKPVHSRGWNYPVRVCDTCVSGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMV5</accession>
    <name>A0AAV4VMV5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_708881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014757">
        <property type="protein sequence ID" value="GIY71129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043921257" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8825" checksum="F28C59FB0BB3A75D" modified="2024-11-27" version="1">MILPLLVIILDFFGDAELGCFHFDFVVCFLVGSDNTKIHHPPQLYPRNCPQHDIRGNAAKPSLIVLAPRVHSVSCNGVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNQ5</accession>
    <name>A0AAV4VNQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_286491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014806">
        <property type="protein sequence ID" value="GIY71429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11926" checksum="6637D5B49F558703" modified="2024-11-27" version="1">MSSSLAGSCTEEGGMKSGIKKGGERMESGQFSPVLGSWRGRRKEEDSCQKEFRVEFSSRREKEKKKKGKKKRGRKHFPSDRIVDFQGQSLRFPSVVMVVSGSLSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNR2</accession>
    <name>A0AAV4VNR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_427301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014892">
        <property type="protein sequence ID" value="GIY72051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12756" checksum="96FDEC3BF03CA90E" modified="2024-11-27" version="1">MLMDLLKQSPSAKVCIEELSSCLSIQKTSHLFVSGGFSLREISPMRTKKRAYRENKCVCCWRQRKSDSSGRDNSSRRGTKRAEGVGVAKMYQLENQKRVTIDENYFRLVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUE2</accession>
    <name>A0AAV4VUE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_790711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015159">
        <property type="protein sequence ID" value="GIY74050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7547" checksum="ECC2388AAB424A5A" modified="2024-11-27" version="1">MDLQGLPTFLSSLVFVLSFFLTVGWNVGVRKEGDAEPFLPCSLLMLVSVMYLVWHRLEITDNRGSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVC3</accession>
    <name>A0AAV4VVC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbonyl reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Cbr1</name>
        <name evidence="4" type="ORF">CEXT_34701</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015139">
        <property type="protein sequence ID" value="GIY73899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF4">
        <property type="entry name" value="CARBONYL REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY73899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="27556" checksum="8BE42A79E581350C" modified="2024-11-27" version="1">MAKRVAIVTGSNKGIGFAIVKALCSKFDGDVFLTARNEERGKSAVEKLKAEGLNPKFHLLDIEDIDSIKSLAAFIKSEYGGLDVLVNNAAIAYKMADTAPFAEQAENTTKINFLQHTIVVNMSSSAGQLSYIPDKNLQQKFLSESLTEEQLCDLMKQFILKMEQIVIHVGGCCTWGVQCNCSRQTELRTAVSWKVHPGYVDTDMTSHKGVLTPEQGAEAPVYLALLPPNVETPRGEFVWNDKTVKSWIGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0N4</accession>
    <name>A0AAV4W0N4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_812471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015422">
        <property type="protein sequence ID" value="GIY75968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0N4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19304" checksum="B230B270F964C831" modified="2024-11-27" version="1">MCMSRNNKCTDDEGSSRLSGQRPYCLSRMERGIIAIDPMTMLASHLTGGLKGSWTGRAGHRQRRFYDDGQSPSLCPVRAAGDDAVAVVPRHTSTYVLRIEGGRDSPRPRRLHDLRGLRDRGYVSHLNVASRGRNRLGRAVNEAIRMGNKSSDQTEEGISHLKSDYKLSEDKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W111</accession>
    <name>A0AAV4W111_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peroxisomal acyl-coenzyme A oxidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Acox3</name>
        <name evidence="7" type="ORF">CEXT_774851</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015367">
        <property type="protein sequence ID" value="GIY75599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W111"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016402">
        <property type="term" value="F:pristanoyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000005">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF390">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="5">
        <location>
            <begin position="143"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="6">
        <location>
            <begin position="323"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY75599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="431" mass="49634" checksum="1654FFD3628C1481" modified="2024-11-27" version="1">MFVSKCGSNAEDLDFTKKSFKIWITLKRGRCITVSGLHIWKTLESDPLFHRTMTEEYKWQEEHHIAYKRMKRLQVYNFLPPELLVEKYHFSPALQNALAMYDLGFYIKKSLSIEYISFVIRSTGTGRHMKILDPLNKLEYSGCFALTEISHGTNTKGMRTEARYDPTTQEFVLHSPDFEASKTWSGNLGQLATHAVVYAQLYMPDGKSQGLHSFIVPVRDPKTLLPYKGITVGDLGPKIGLNGLDNGFMMFNQYRIPRESLLNKNADVTSDGKYISVKHSEIMSFIKIINCRTKRLFKNLMDGYVNHKNSYKRRNERFGDSMGALSMGRVGIIMLCVNFLRLSVPIAVRYSALRKQFGPNPSEESPVLEYQVQQWRLLPYVAATYVCYYFARDFYQDFIDYFVESLLTDGKSPENGKHFVIFGILYGNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W631</accession>
    <name>A0AAV4W631_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_797921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015688">
        <property type="protein sequence ID" value="GIY77843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W631"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13132" checksum="9BF0178BF14B50CC" modified="2024-11-27" version="1">MRYSYMQALNSALDYLFVKISSLVNLLPVIPYTRAPLASPIRFCHISISPQKQAFHLKKEDPPANAATYVSKLPLVNLLRNPLHPRTKLASPIRFRHISPSTKASPPLKEGRSQVCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W663</accession>
    <name>A0AAV4W663_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_366881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015690">
        <property type="protein sequence ID" value="GIY77873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W663"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="293" mass="33741" checksum="7D992783852CE605" modified="2024-11-27" version="1">MKCIPRNTFAVSEKSYSDRWDKHGVFLERVNMCWRRSISRERWNIFFFFFAFFLSSLFPTHRPSSCCSQGVLLLPRGAIAANLTEKSHCVDFNIAIIYQHHFRLFGCDRKYLGAPRDFDDDEFHRSCWRGWISRERKVGKFGRGSGIRTNTNVPGECITNQYGISCKVPIQKKEEQDGSHNTASLLTIECFPYIFLKTLTSLDSSFFPETKCFLLLHRSRERQNHDSASLACCNATSSRLNVVCSSAILKIPAHLRRFEMSILGFCNTRDSWKQLPQELLRAISSLASFLTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6Q7</accession>
    <name>A0AAV4W6Q7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_517441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015698">
        <property type="protein sequence ID" value="GIY77923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6Q7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10691" checksum="39DC74D523410432" modified="2024-11-27" version="1">MYDVISLVRNGLPFFPESKTSVSIEINEHSTYNSFPRTSHKSNREKEVPLENQNKPQCTVTEATPFHPISRETRPHRGTFLYIYPPSSFYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WB98</accession>
    <name>A0AAV4WB98_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_618431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015986">
        <property type="protein sequence ID" value="GIY80230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WB98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13862" checksum="C99B26B1D7EDAEA4" modified="2024-11-27" version="1">MKTLEKSHSRRHCVGASENHITTAVVRAVMFATTFEQLPPQFSTPPTERGGKRFSTNYYLPVVLQSFCQVRVFIVLLVGSARRHTLRMSPSPNFRYLLVLLYHILWQWFFSPYLLLSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBJ2</accession>
    <name>A0AAV4WBJ2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) RNA polymerase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_710412</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015998">
        <property type="protein sequence ID" value="GIY80335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF127">
        <property type="entry name" value="SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="660"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="8">
        <location>
            <begin position="103"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="7">
        <location>
            <begin position="355"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY80335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="686" mass="79218" checksum="FB37D97C27DEE6E4" modified="2024-11-27" version="1">MIVQKCFCCLRNRSSKLLPLVHRNKNALRTYIITKAEREKIVKLCTVISTQVNNSFKECSTSPLKKAENTANHQSFELENMHIDGPFSHEELITSLYRCKTVSEQMEILSSTLGLTPEDIQSRKKFSNTLASLYKPFFENVKINVFGSSVNGFGFKGCDLDISFETSVERKEKVTQELVPSNFLISQVINGEISPKEISNLHPKEQLVFAYYIMMEYFKELKNPLVSLNPHAPLVRFTYDKFNLKCDMTFKNKNASVNTKLMLLYCKMDKRVVPLLMTIRYWAKHLGIIGKGRTFKSYTISLLVIYFLQTRKPQVLPSVESILSLSVDNFEHAGIEDQSFLNILQKILHLKISKLQEFFLFYLNFDFTRVICPINSKAIPREEFKKENSKFKMHDICIQDPINLQNNNGGVVEFQCWKTFSEELMIASNILLNNVMLNPSQNPWGLISILDHPKSFVDDLKSLQLISFSVPVLTQTVNGKISGSERISVTSDTLLKLLQHGLMFKCKSLEMEALTNLLEKQDKLIYKSNLKVAKREESVLEQFQTLNATNDLVFSVECEAAHNIFECRDLFHLDSSFDSKSVLDREYLISSNIAKQDKRNESKFLCECYSSRTLPTTMFLIFEPHHKPYFNPILGISLKHHILNIMERRTVIIFANKCFYYMYIVFIDKICTSVIVIISNYETFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFS5</accession>
    <name>A0AAV4WFS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_790491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016045">
        <property type="protein sequence ID" value="GIY80699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9299" checksum="2EA1317922FD567E" modified="2024-11-27" version="1">MNLTNEAPTLTSEWIFPECPEVWSELEAKFGSLNTLNLTKLRALPPSFSDHNRNRKVIMASETNFCPLPKPLKHHLRLIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIB2</accession>
    <name>A0AAV4WIB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_392521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016145">
        <property type="protein sequence ID" value="GIY81599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15006" checksum="E322AEFF240E72A0" modified="2024-11-27" version="1">MSKVSELQSLKTFIGRGISKTISTKCPTIRFKFPNNLLPAFRCKRMHSNISAAQFFLQADVPCETLMMPTRSLTTYFREPFSVHFIQYLNLKAVPGLSPKVWMAHSCPIRVHLLPIKYTFVNNEMRCSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WNW7</accession>
    <name>A0AAV4WNW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_191301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016348">
        <property type="protein sequence ID" value="GIY83175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WNW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14689" checksum="13052FA17196A7CD" modified="2024-11-27" version="1">MGILHQLGIERVQLFHNYSNKRTNRDTRNGAGIISTERDDKSLQIVPSAGDTIPEDIWWDAGEGNVAFISNLHAQSPNHQKRWEGERRFDVGAQPAGEEPTPQRGDSFRFCEGFHSFSRRGIVKSKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUS5</accession>
    <name>A0AAV4WUS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_763451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016655">
        <property type="protein sequence ID" value="GIY85399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10301" checksum="350F6C3A34F69CAC" modified="2024-11-27" version="1">MIIRDIFECKVKATWGIIRDTCLSFYAIGTLCPNQVFGDVVLLNINKIILSADPKKRVLNDCYQYKPNRFMQRSLGLIETEKRTLNKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZJ4</accession>
    <name>A0AAV4WZJ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_430991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016914">
        <property type="protein sequence ID" value="GIY87256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11719" checksum="C646A0F7F24E08D8" modified="2024-11-27" version="1">MIAPADRRPNGKKSEERQCHEIRLERLGFYQSVATTLCRGIFLISFFLFPRWFGLDRLFSFPASLLLGGFDLLLLIRFGRLLLFHFLELRSEQMMDPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X6R8</accession>
    <name>A0AAV4X6R8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_327721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017208">
        <property type="protein sequence ID" value="GIY89464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X6R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10459" checksum="23FDA987B160526B" modified="2024-11-27" version="1">MESRKISSTFRFHFPLKLTNSSFSLFFPSHSNYRLRAIWTPNGEESPEIKFDWELLLHTSTTTLAEETVPGIATLTCDKRYLMSRKLSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD25</accession>
    <name>A0AAV4XD25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_754821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017621">
        <property type="protein sequence ID" value="GIY93082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9493" checksum="84BC1AD1720BA7B9" modified="2024-11-27" version="1">MDGTVVSRGRDPFPSESSRRHSNCKWRCKPFSLYINCETRTLWDFGRFALIYADQDQRGSGGWERLLLDRDRYAYPQENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFC9</accession>
    <name>A0AAV4XFC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_810741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000304">
        <property type="protein sequence ID" value="GIY93777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14023" checksum="40DC59F429B99DC5" modified="2024-11-27" version="1">MYELNLFRKIPLPVLGPPPRRPFPGPAPQPKIDLPPLSPRPPQRRDPKSLVLNSVDNDPQNRNPSEKQKSNPNDRQNEKDKRPKDTRKPQPWNPNPENKYKNLFDRGNVGEKDNACNCQCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL39</accession>
    <name>A0AAV4XL39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_219161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017970">
        <property type="protein sequence ID" value="GIY95857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10382" checksum="0B023DEE4D75D191" modified="2024-11-27" version="1">MYDDACRSVQDLCTLDIEVVNHVTAPLFEKKNTNNSPESASFPRSDSLFSFSPVPHLRLSVDGFLFTPNYSNLSFQLLKHGQLFIIILNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPP3</accession>
    <name>A0AAV4XPP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_394961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018068">
        <property type="protein sequence ID" value="GIY96628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18979" checksum="21683FFD3CF9BE1B" modified="2024-11-27" version="1">MLKYFQYKKVSLHSVVGSCNKFIHFPARARLPTPADICLSIKTSVKRNRNPRHPPPTSRRGISKMLQQLTSDDNGGPAGCRATPSYSIPPPYPAHRTTRRVTPTVGRERVVPKVHFPESRCVALQMTHRYVRLNEWMDGRRKEEKMHIREGIVYCTYFGLVQVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR26</accession>
    <name>A0AAV4XR26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000811">
        <property type="protein sequence ID" value="GIY97641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="25628" checksum="58A3700CD96DD899" modified="2024-11-27" version="1">MEVDDDGCVHAAGKSPPKGSCVVPATPGNVTNLTTTSDMNMDLALTTAPPIINEAQHCQQLLQAEKEAAHQKKKFVNAANIICDQDLLDKMSTAKLTKVAFTKAEKEYKAALQRVSDIGLCPLVNCSRHSSAKIKCVSGKNKRTAQTDEFILPTKKQTAKIKVQNAKDIINVSNGFDQLTVDETGDGGQEVPEPKMPPIMAVLKGVPTEYNEEEVLEALTQAGYKIEKGEATHQPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX19</accession>
    <name>A0AAV4XX19_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CEXT_232301</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000932">
        <property type="protein sequence ID" value="GIY98534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002325">
        <property type="entry name" value="Si:cabz01021430.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001155">
        <property type="entry name" value="Zinc finger 30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000151">
        <property type="entry name" value="Zinc finger and SCAN domain-containing 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001009">
        <property type="entry name" value="Zinc finger protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000710">
        <property type="entry name" value="Zinc finger protein 768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000099">
        <property type="entry name" value="Zinc finger protein 79"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="683"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="711"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="739"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="767"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY98534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="819" mass="92744" checksum="3FA2BB6AFBDA4FCC" modified="2024-11-27" version="1">MEYEGRWSSMSQCYSSTQQSILPDICQRTGYEIKAATEMPPKYGFSNQNAYNPETPEFLFPGMHPIPENDPHSTHLLLPSEASDAFTNQYTQYYEPINPEHLSSIPGAVTKRCILTGSQHTFSQKNELMHQMIQHPNASSQMESSLISSTKESQPHFSSAYHNFGEIDHILTNETSKYSETASEIPILNIQNAQYCTGNPIHPTDSIEQIEAFPFTMSTSDYSLDNLSPSINNLFQNENPRNITDAISLLGAYQISVENQESRVTNLDAIKFKGEDSNSKIKQWTECNYGKADSDSCASNSNQDHQPYFGSGIIGHYTELRKWEYLSSVTCSPEKQKACNISTITTANESKATYKNPSEDKVLRRIANSSRRSRTPQNTSAPTLARHRIDVRNAVKAFLTLTNCATTTTSTLAKKPFSCGQCGKRFPLKDSLNKHLRIHTGEKPYSCSECGKCFIFSFGLNAHIRTHSGEKLYACNKCSERYARNFDLRNHMRQHTGEEREKNYITNFEVHNCVRFGNQYRRTSATLPQRISDINSLSGNRKENTDISEPENPNNITDAISLPSTSQYSSSVICFSERQKASKTSTTTAANESNATYGNHSEDQILCRIASSKELDTTFGNTRKELYKCDKVRSSTLPTDRLAFSERSHGVARPNRSNFCDEAFADSSSPSTLVRKHPGDKPYKCAECGKCYEYPSQLSDHSSIHYGEMRYSCGECDKSFVYQNSLNKHLRIHTGEMPHTCRECGKCFAFHSELTRHTRPHSREKPYACYKCCKRYTRNSDLKRHMLKHADEERSKCNSCGAEFSFEESLEAHECRKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYE9</accession>
    <name>A0AAV4XYE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_216201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000994">
        <property type="protein sequence ID" value="GIY99029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9714" checksum="504106C92B6D9B4D" modified="2024-11-27" version="1">MHGSYKINKSKPNESEIHNTPRKLDFRLLSAVVLPAVSKQLLSGITTLPQTRKRDFNFKAVKVNGTRVLFGCRFEAGRHNSTKCGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYK4</accession>
    <name>A0AAV4XYK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_490001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001138">
        <property type="protein sequence ID" value="GIZ00241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8654" checksum="991DD25900BFFFCE" modified="2024-11-27" version="1">MRQKRLTQTPPRSERNWRVVQEWMPDEASAEMLDGMEFGFKKGVLAVVYRPKAINCILEFKIAGGCCMWKNWCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y041</accession>
    <name>A0AAV4Y041_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_183891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001034">
        <property type="protein sequence ID" value="GIY99345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y041"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9122" checksum="41B909178FFC038E" modified="2024-11-27" version="1">MHFFTFPISLLRDRKSNLPPISSSNLPEYSFADKSIPCFTDMTLSPPSKIELSALSFAILYHYTLKPAKLENCFVDSFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0M8</accession>
    <name>A0AAV4Y0M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_595841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001146">
        <property type="protein sequence ID" value="GIZ00364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16456" checksum="D18565B7ACDB4308" modified="2024-11-27" version="1">MRVFLRGAPGLLNCNFHFSRDFGVVLKIGFPANERKRSHLKKKKVLCLRGCRWEWTATYEEFQKYRPPQDSSFLLWALVIIFRPQWQPLPAARVIFPFVERGGGIRERVGSFSGPNIESGWGILRQNQPLMEISSTSTLLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2R3</accession>
    <name>A0AAV4Y2R3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_354421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001262">
        <property type="protein sequence ID" value="GIZ01174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10785" checksum="B7140883014F4CBA" modified="2024-11-27" version="1">MTLSPRRWNRTTLTHISHGFEAHTRPLALIWATLGLCCLFRPDERQWSGARFQPIADENQSGSIPHSGRERHGDVEHMLSLSSTYEYPFNLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAE0</accession>
    <name>A0AAV4YAE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_552521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001714">
        <property type="protein sequence ID" value="GIZ04288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9140" checksum="E9B47A806F12FFEE" modified="2024-11-27" version="1">MERERKRSRVRKTVSYPRNEAKGVNDQDKKLPASIGGVDTQGTASFEGCSLQTRSWCKNFNHLGAQVPVPPFDTLIFFNEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAW5</accession>
    <name>A0AAV4YAW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_48233_1</name>
        <name evidence="6" type="ORF">CEXT_560172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Has antibacterial activity.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001713">
        <property type="protein sequence ID" value="GIZ04278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0800">Toxin</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043383102" evidence="4">
        <location>
            <begin position="17"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="5">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIZ04278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10630" checksum="5B97953F088C990E" modified="2024-11-27" version="1">MKIVFLLTCLIVGVTTFEAFCPARYSWDCPYFVNECCSDYDCEENQLCCEENCGNTCQFYSSYPTNGHRVEYYSYCRVDPRFTHPPHIPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDI3</accession>
    <name>A0AAV4YDI3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">Cyb5a</name>
        <name evidence="16" type="ORF">CEXT_449431</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Microsome membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 14">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001735">
        <property type="protein sequence ID" value="GIZ04430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000002">
        <property type="entry name" value="Cytochrome b5 type B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF150">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 14" id="KW-0349">Heme</keyword>
    <keyword evidence="9 14" id="KW-0408">Iron</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="15">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00039806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIZ04430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16147" checksum="0CB02E8D3BC83029" modified="2024-11-27" version="1">MGDTKTYTLEEISEHQDKKSVWILIHGKVYDVTKFLEEHPGGEEVLLDQAGKHATEAFEDIGHSTDARDLMKQYCIGDLCEVLYSFVITWKTRKKIIEIEEKNHWPVGGGDESSWKNWLIPIAVAILASLLYRFYMSYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDY6</accession>
    <name>A0AAV4YDY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_207101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001703">
        <property type="protein sequence ID" value="GIZ04221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10210" checksum="B1765AD26845901C" modified="2024-11-27" version="1">MPFFYQSVKTLVVKDLLAHLFSKHLSMAIFLLATASLMQLGTRCITPCYYPINPATTTTKPFPINLLRTLRVKVHAVEYIYTVYTWPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4J2</accession>
    <name>A0AAV4M4J2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_258621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019338">
        <property type="protein sequence ID" value="GIX66750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4J2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8421" checksum="01CDDD8120A3C8D9" modified="2024-11-27" version="1">MLKKKKKKPTDANIEREKSVAIASEWECESTKALPEIPGTILGKHFLLTCLAFCKYFSFFETHAEWNGGKRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MB48</accession>
    <name>A0AAV4MB48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_551871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002027">
        <property type="protein sequence ID" value="GIX69244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MB48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11454" checksum="771EE3F45B9E4329" modified="2024-11-27" version="1">MDNERPWLHTSSSLAQQPMVGQGLCSILRQWPPSKNRPLRELGGPDQEADQDLQEEEPGGHGVSEERGSIVHFRVPMAIQDPKVELQHRQRYQNFRQSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBS8</accession>
    <name>A0AAV4MBS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_42461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019529">
        <property type="protein sequence ID" value="GIX68861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="149"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX68861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21467" checksum="8F48AF13FB341B0F" modified="2024-11-27" version="1">MSSCVDQNSRTELFFEVRGSQPVYAQAIRIVSVPLLILSHLNHYSDPYNSCYKRTRESISRTTYNLICISVGRTLGALSLIIGDHLAVPINYYHPVVLLAHDFYCEREGNTTRRRVNGDEERSVPREDEVHKHEREERGAPAQVHPAAAPRLLQDHKELLEENETAKKELENLKDNYKAVMKIIWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKT3</accession>
    <name>A0AAV4MKT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_792861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019824">
        <property type="protein sequence ID" value="GIX72162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13015" checksum="858A05FF2A691E2D" modified="2024-11-27" version="1">MKRKTVLFPLFNTFLQHYPHLPLLKNPALKNKVAIFTPHEIQYLVFAIPKKRMDPSMNIGLPLLEGGERSVWDNDSPERRHPPPAPNEIILCCYLDSCYQPWFWWGVNISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVT7</accession>
    <name>A0AAV4MVT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kelch-like protein 35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Klhl35</name>
        <name evidence="4" type="ORF">CEXT_432231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020256">
        <property type="protein sequence ID" value="GIX76483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632:SF3">
        <property type="entry name" value="KELCH-LIKE PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632">
        <property type="entry name" value="LD33804P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BACK" evidence="3">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX76483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="391" mass="44623" checksum="ECB2905E3E14DF76" modified="2024-11-27" version="1">MEYILKCDFPVDCSESEVLSVVLKWIEHQPHERFKYIHQLLRYIHFNEISSVDISSFFESPVLKCLCSSSTLWSRLWHVSRHSVWQEQQCMSLINSRGMELAILKVGGFGISGVTNDIAYYLSSIGKWRYLTSIPHVEQCNFGTAVLNNELYIVGGCFNQSLQENVHPFGFRYNPLTNSWELGDFDVLDDNSPCEKYDPATDIWTPVAPLPGSRTQHAGTSWRNFFYISGGLDQDVVLSSVWRLNIDTDQWEVKAPMTTPRADHSMVCCGDKIYVCGGWYEDENTGSRVLVDSIDCYNITRDSWSVITRVPTPRYHAGIVVIGKWLYIVGGFHSATTFDRASGVVECYNIETGVWTVGDNYPQDIWEHACCTLYVPRCRDDLEVIPDKNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXE9</accession>
    <name>A0AAV4MXE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_58701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002713">
        <property type="protein sequence ID" value="GIX77068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="18261" checksum="B7D003B4C8C26D18" modified="2024-11-27" version="1">MLRLVAVTNVHLCVCALYHPFQLACFPYRKKLLLRRSFPVCVWSNQIAVSGFGLLGLARFAMVEALIRRVKISLGFDFGMYFLFFHGFSYFCFAIWMVRRLQLLFLVKCNVFFVVLRSWHYGWKWIDKRMLFTRLIRFLGWYQRGISFKFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZ67</accession>
    <name>A0AAV4MZ67_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">E3 ubiquitin-protein ligase RNF10</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">RING finger protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">rnf10</name>
        <name evidence="19" type="ORF">CEXT_807941</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="BPLR01020310">
        <property type="protein sequence ID" value="GIX77226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZ67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16536">
        <property type="entry name" value="RING-HC_RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000112">
        <property type="entry name" value="RING finger protein 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039739">
        <property type="entry name" value="MAG2/RNF10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983">
        <property type="entry name" value="RING FINGER 10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="176"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="619"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="657"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="619"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00035131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00035390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="GIX77226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="689" mass="78162" checksum="8DAF46ADD6BCC042" modified="2024-11-27" version="1">MEKGNAKSSSSKSNSCDSKNKQDVPNKYFRLPRAKDNISPRPDTRKKSNNPQRNRELFDKRPRNKTGTVCERYRREMTEGAVGDSTTKQGCKKTNLNYLLNFSLAPPDNWDGNGRRRIQNRTKLPKYNKELFLQANCQFVARDNGNYTVHQKNPDILVEWSLIEEIRLPCHEVPSCPICLFVPVAAKITRCGHIYCWPCILHYLALTDKSWQKCPICFEAVHKTELKSASLMIRRSIAVSDDITMCLMRREKGSLLSVPVTQQKITDSLCNVLEVDSVTRYQKLLLACPKEVQLIINRERLELNQAYENDKDTPEACFIESAIKLLDEREHNLNQVLDNEINKAMTEKLVGVTRKHLTSISSADSNDESLNFEINENSSKVGSFTSKSLMQNNSTDSDSKGVCFFYQAEDGQHIYLHKVNVRMLLKEYGSLEFAPPIITAKVVEIESITMTENLRSRLRYLQHLPLTCEFQVVELDFSRMVSELTVQQFESDIKKRKVQRIKKARDEKRREKMIEEQENKKLGKYPKATYNLNSVDQFPSYNPEDFLSLSPPKSGTNGDTSITSQDISDIHANCDVGSDCSGIAISESYCVPLTSFAQMLKDGPKSFTQVSKDLVKSNIASSPQSHSTVDSDGGECTPAPEYRLSFGDAFQAALDAATTQTSDNQSSKKKKKGKKKQLLFTTSMNRNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZL2</accession>
    <name>A0AAV4MZL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GPI ethanolamine phosphate transferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PIGO</name>
        <name evidence="2" type="ORF">CEXT_383191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020304">
        <property type="protein sequence ID" value="GIX77178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039524">
        <property type="entry name" value="PIGO/GPI13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071:SF1">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="42238" checksum="B3166CE53B81A2FA" modified="2024-11-27" version="1">MIHGTVFFPNTFHRSFSFPSFNVKDLDTVDNGILDHLYNEIDKNDSDIIIAHFLGVDHCGHRYGPKHPEMARKLQQMNNVIKNVTEKLKNDTILLVLGDHGMTENGDHGGDSIQEISTALFFYSPKKLTTYKYTEEIQTVAQVDIVPTLSLLLGLPIPFSNLGKIISPLFMLNHQETCFNEMTDSVVASSLAAEENAIQVQRYLYAYNEISNELSHSFMTRIEKQFQDLSHMWSKINSNITESRDILFNISEEIIPVVIFLGVMIYKYSIKSQSVSAVCVKYGIFFVCVLTSLRWWLNIVSPNIVDRILKGNEVILTRSALLTCIIMFIILTFFPILVEKPWEIPSKEIYCGSFCISSIYCATDVIFGWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N254</accession>
    <name>A0AAV4N254_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">superoxide dismutase</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sod-2</name>
        <name evidence="9" type="ORF">CEXT_398931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01002818">
        <property type="protein sequence ID" value="GIX78078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N254"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000003">
        <property type="entry name" value="Superoxide dismutase [Mn], mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF6">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="8">
        <location>
            <begin position="7"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX78078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13139" checksum="68E7D059680C840F" modified="2024-11-27" version="1">MPFRREPEGELLAAIKSDFSSLDNMKNLLSTAAVGVQGSGWAWLGFNPVSKRLHIAACPNQDPLQATTGLIPLFGIDVWEHAYYLQYKNVRPDYVKAIWKVANWKDIGERYAKAKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N384</accession>
    <name>A0AAV4N384_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_537051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020399">
        <property type="protein sequence ID" value="GIX78290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N384"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11550" checksum="45F98A69A44A2EBD" modified="2024-11-27" version="1">MLHFFSVLGNNRTWAEILKRVVSLNSIFISIPSVNRNNGMHPFILRIQLLGIEHSVLGNLTIFFLEISRSTRNKEGVLPSIMYILLKNGITMTLPATVHFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3X0</accession>
    <name>A0AAV4N3X0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_758421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002947">
        <property type="protein sequence ID" value="GIX79522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3X0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12533" checksum="7BC7339359F5F6B4" modified="2024-11-27" version="1">MGINYSHRDFASTYFHRNRSAKMKGKGSAHDKNAFWRSATVHTRKKISVKAFLLRINVRVHWRFEERRNCREMKSLSKNNMSMLRIRNGCSAVPYSCGVNWKRIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7W6</accession>
    <name>A0AAV4N7W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002952">
        <property type="protein sequence ID" value="GIX79572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10237" checksum="F641D35D44783DB7" modified="2024-11-27" version="1">MHTTARTHRFRKRVPFESKTRKSDCHRLFTELALFTHDISTESTAGALLIYKTQAAVLPSHKTSPQTFYLPISNLGRLLEGIEKNPAKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9Q8</accession>
    <name>A0AAV4N9Q8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CCR4-NOT transcription complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Cnot3</name>
        <name evidence="12" type="ORF">CEXT_396211</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003125">
        <property type="protein sequence ID" value="GIX81418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9Q8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="11">
        <location>
            <begin position="4"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="256"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="41"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX81418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="647" mass="73458" checksum="0849AF26B1ECEA06" modified="2024-11-27" version="1" fragment="single">MADRRKLQSEVDRCLKKVTEGVEAFDDTWEKIYSAANSNQKEKYEVDLKKEIKKLQRHRDQIKTWLTSNDIKNKDPLREARKRIEIRMERFKAVERETKIKAYSKEGLGAAQKLDPAQREREVTNGWLTACINALNIQIDKFESEIDLTNLSLKKKKNDKEKLDHVEDLKKKCEKHKYHINQLETLLRLLDNRSVEVDQIKKIKDDVEYYVDCSQEPDFQENEYIYDDLDLENYEDYLAKQQTAPQLSQIDSKHAALEEENSTVISNSPTSTASNSRSHTPCLENHFSQESKVSESNSSSNNLHQLPSPTSTNKNSLSSECSSPVSSHMNFYNSQSVINSQTSTPFATAVANLPNNHSKMSNNHELWSSSNSLDEELNNDTNAKTLHLTNSFDALHNNTNHVSKSSVPVSNSWTDSSYNNKYNFQNIEFSSGIHCDSNNQQFNNGDSQLHTSTESSKNVASSVNCQNNTIYTSYGSSLPLNVSSNSVILDDVQSSLKNLAERVVLSSGVNNHIHNLQFSTIENKGSQLTHNVFGNNANDIFMNSALSLTTKPSPSMTSAKINISQIFGEFPENSFTPDQKRALSTLENAQKRLPMPIDSQRARLHGYSFPASTPDYYPSSALPNEFTLEFFLRLSTETLFFIFYFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKS7</accession>
    <name>A0AAV4NKS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_703481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003512">
        <property type="protein sequence ID" value="GIX85417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11197" checksum="206705390124FAA7" modified="2024-11-27" version="1">MAVKGHSQMDFFKSCGLPVCEIKTEVLGDCPKYDELPIPSEQLNKPCEIHLAGDDYRCSKRVAFTFARYLESREGDQLLVLQPDEMDDDGEVNESVIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUM9</accession>
    <name>A0AAV4NUM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">jockeypol_218</name>
        <name evidence="2" type="ORF">CEXT_130551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003702">
        <property type="protein sequence ID" value="GIX87666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF4">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="170"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="545" mass="62406" checksum="F1D80053D8E3E9AD" modified="2024-11-27" version="1">MCILLKSAAPSMRSVLSRDRFLKLTVTSEVEHLRLKNKLVQLGMEFKCFNLKQDRPIKPPASNRSNFADIAAGRATSLTPPTEAPLNKSAMEFFKLLLAYVDDQSVDFDILLDAVRAALPALNTTNDHHEKASHQPALSSGRFLECRWHPPPIRRGKGTPFEDLKKLQKIHNNVIFAGDFNATHTSWNNSKNNQRGVQLNKFLNENNHRIIAPTSATRIDPRYNAQNIIDFATFKNIPYPATAAVFQELSSDHLPCLLEINLNVKPQTIPNLFITNWDDYNFNLQRTNLKLTTINNEEDADNAIENFTKDLYAALNNSSKPKYLNIKGRLPKEIKLMIKNKNYLRRLYQRSRDPTIKEAYKKLENKIKTKIYIYKNSVWEKHTDSLTENQTAFWKEVKKLRKSPQIIPPLELDANNMALSPAEKAEKIADCWKLQFELNPNTSHSFTNNLIASETEKYFNCPHTNYIQNVTATEVIKFIKSLNPKKASGIDNINANMIRFLPNKYLWRPGFDSRHGKMRFHGVMVSTLDFESSDPSSNLGGTLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVA3</accession>
    <name>A0AAV4NVA3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RanBP2-like and GRIP domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RGPD4</name>
        <name evidence="3" type="ORF">CEXT_480251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003799">
        <property type="protein sequence ID" value="GIX88807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000018">
        <property type="entry name" value="E3 SUMO-protein ligase RanBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="102"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX88807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="415" mass="46412" checksum="434620C00E9BF104" modified="2024-11-27" version="1">MSKFNYYIHFLGSSADEPTIPATVEQSLELPATSPNTNVPFSTSKFASFSFAELASKASSDSLTKSSPSSKNIFADAGAPVFSNLNTTGEETDEVVQSGDIHFEPAIPLPDLVEVKTGEEDETPIFVHRAKLFRYDSNTKQWKERGVGDIKILSHKEKVRFRIILRRDQVHNVACNHCISEDMSLSPMATSDTALCWNALDFSDSPNGEASQFAVRFKLKETLDNFKQVFNNCKEQLVNQPRNTSENQITDELSSTLKLKEESETSSESTPDVVNYGTESKTEESETDSDSSSEEDVLFEKRATLEIFDEKAAKFMSVGIGKLKIVYDDTVFGYHITMKKDNGETMCDHIIAVQTCLRTEGKRAMWAALDLNVEPVVRKQFCVTFSSYEALKEFSLCFEEGKEIAIKSEIVEKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0N9</accession>
    <name>A0AAV4P0N9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003912">
        <property type="protein sequence ID" value="GIX90090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0N9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9638" checksum="2F300991F2A134AD" modified="2024-11-27" version="1">MAAHCPCPYSIACNEMKWKINDAIKNYYVTQATEKHHVLLLANFVPDNLPKHMTIANFRLMISYGYLQGNLYRIVILPSPDCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1S5</accession>
    <name>A0AAV4P1S5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_242861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003953">
        <property type="protein sequence ID" value="GIX90589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1S5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9584" checksum="1ED5C22406DC90FF" modified="2024-11-27" version="1">MGMVLGVDVSLKARVCIIETVTESMTGRRRAVDVKRYRLGCRWIFCRNYNSGEGERAGICGRLSSGNRLVTLRAMGKESLGFLQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3R6</accession>
    <name>A0AAV4P3R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_687141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021458">
        <property type="protein sequence ID" value="GIX89847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8329" checksum="435FBA25423A6782" modified="2024-11-27" version="1">MRLVATFGPQEAFGMAPQSSWTRCRRPVEDTSCVTCAALADCKNKVVGTQVTPLMGSVWPHVGCMWAAICRTELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P933</accession>
    <name>A0AAV4P933_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutamate receptor ionotropic, kainate 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Grik1_4</name>
        <name evidence="1" type="ORF">CEXT_574241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004266">
        <property type="protein sequence ID" value="GIX93564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P933"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11160" checksum="611A92E68CA26C10" modified="2024-11-27" version="1">MRKKLSFSTILTTVVGNLFKQPVNVTISTVSIRILYSFLVAVCDPNDVELRCCFFLSFLTVPLREKGVQTVMELCQAVKTGSYKALMPKGIFFAVFDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA74</accession>
    <name>A0AAV4PA74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_23461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021719">
        <property type="protein sequence ID" value="GIX92819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15593" checksum="74F42FCDBEE92ECE" modified="2024-11-27" version="1">MSLMQVSPLSHLHNRGQAHPLHLECEGSGGPSIRGRLYQPPDQVKCGAELANLGLSPPRQNMLLRQHSELRGRDFAAGVGFGWVGGYELRGGGWRLFFFYYFWGEERNGMLYHQKDYFRLRYPQNFKNTACDIKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNS1</accession>
    <name>A0AAV4PNS1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Septin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Sep1</name>
        <name evidence="11" type="ORF">CEXT_24331</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004956">
        <property type="protein sequence ID" value="GIX98731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000064">
        <property type="entry name" value="Septin 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="10">
        <location>
            <begin position="33"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX98731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="359" mass="41226" checksum="C636E0692363129C" modified="2024-11-27" version="1">MSTEAKLFNNPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERHIPDAAEASTVEIEERGVKLRLTVVDTPGFGDAIDNSDSFKSIIQYIDDQFERFLRDESGLNRRNINDSRVHCCFYFISPYGHGLKPLDIEFMKQLHGKVNIVPVIAKADALTKKEMMQLKKRIMQEIDENGIRIYPLPDCDSDEDEEYKEQVKQLKEAVPFAVSAALPTIEVKGRKVRGRLYPWGVVEIENPDHCDFIKLRTMLVTHMQDLQEVTQDLHYENYRSERLAGKTNARKPSVSPEQSDKDRILQEKEAELRRMQEMLQQMQQKIKEEEQRNATPSPTNQSPKISHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PU47</accession>
    <name>A0AAV4PU47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_287361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005179">
        <property type="protein sequence ID" value="GIY00436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PU47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="24330" checksum="69B67AC991F98D34" modified="2024-11-27" version="1">MPIATGFVVTVAPRVGDLCLLLVSVRTKDAFISLGCYVPEICAEGLTCEKEVYRVMKNLDSHGRCKFVQINVIRMRLRRKRFSSPQISQVLTLNPQNTAQIMKRSVPMVHFLKMNRDRFLEEEEDKSASMLASNQSLRSPPNNGSRSGMATSKLSQILNLLPSTPTLSDPLRAHVNRGSWIPGSGVHLGTLGILQGVHHLPHNVWHASKTHSESQLSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXH2</accession>
    <name>A0AAV4PXH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_740791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005323">
        <property type="protein sequence ID" value="GIY01450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="57" mass="6313" checksum="197DD7C10B783E2C" modified="2024-11-27" version="1" fragment="single">MVQVCCIATKNYCIALPLFGSTFFIHSSYSQFMSGPTQVQPQSTSTTEKHHPCTSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PYW7</accession>
    <name>A0AAV4PYW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_221471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005320">
        <property type="protein sequence ID" value="GIY01409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PYW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15634" checksum="2818F027B4796864" modified="2024-11-27" version="1">MDNRRKRVDRFMPIITILSLTDKTELTNLPTPGPVNNKKFVYMELIISHAREQATLFPFENIHHCYQPYKYDGKHCSPVEMSCSPQRRNLAVEPKEEREYPKKNNCIVILYAPVSKGTKNKSNVVSLGYCEAIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0U3</accession>
    <name>A0AAV4Q0U3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_366491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005413">
        <property type="protein sequence ID" value="GIY02136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0U3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="49" mass="5429" checksum="2178ECE915D9BD37" modified="2024-11-27" version="1" fragment="single">ALYHDKDGIIYASDGKNDLPPDISLEVFTNELEGDENTTITGKTLYFPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3D1</accession>
    <name>A0AAV4Q3D1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_346351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005522">
        <property type="protein sequence ID" value="GIY02949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3D1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043585076" evidence="2">
        <location>
            <begin position="24"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY02949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="673" mass="62614" checksum="555AA4653945826F" modified="2024-11-27" version="1">MAGGNLFTLCLVGLVFYVTLNDARPAVHHVDGGGGNVHHYKTNGTGTGNVHHYKTNGTSQTHHYQTDGTGGGNVHHYKTNGGAVEVGGGSGGSGGGGGSGGSSGGLGLGGNGGGGGGSGGSGGGLGLGGNGGGGGGSGGNGGGLGLGGNGRGKGKGGRGGSGGSGGGLGLGGRWRRRFRWKWWRIRIRWKWQRKRQKSGRGGSGGSGGGLGLGGNGGGGLGLGGNGGGGGGSGGSGGGLGLGGNGRGKGKGGRGGSGGSGGGLGLGGNGGGGLGLGGNGGGGGDSGGSGGGLGLGGNGGGGLGLGGNGGGGGDSGGSGGGLGLGGNGGGGLGLGGNGGGGDSGGSGGGLGLGGNGGGLGLGGNGRGKGKGGGGGGLGLGGNGGGVSSADLPDLSQISKGDLANALGIPKSELPDVSEISFSKLPSLSQLSKGDLASVLGLPASEIPDISQISFGQIPGLGLGSLPGLSSADLPDLSQISKGDLANALGIPKSELPDVSEISFSKLPSLSQLSKGDLASVLGLPASEIPDISQISFGQIPGLNLPSLPGLGLGSLPGLGLGSLPGLSSADLPDLSQISKGDLANALGIPKSELPDVSEISFSKLPSLSQLSKGDLASVLGLPASEIPDISQISFGQIPGPLRDSNEPRPKLTLNNPEDLVICLLDMKLKKEFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6X6</accession>
    <name>A0AAV4Q6X6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_594531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005546">
        <property type="protein sequence ID" value="GIY03153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6X6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13098" checksum="01DDF09412C806A0" modified="2024-11-27" version="1">MTLIRSSTVGFVIFKLSIHRLSCGVNKSKSRYVFAKEAASQRVLLFNTWLLKLGFETFGEFAFCLLGELAPKWIAATSGTGILPCHVRPYGRLASAAVRLHLSTPSFTTRLFVFRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFZ8</accession>
    <name>A0AAV4QFZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_683431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006064">
        <property type="protein sequence ID" value="GIY07182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043315833" evidence="1">
        <location>
            <begin position="30"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="7634" checksum="9079006B045E4630" modified="2024-11-27" version="1" fragment="single">SSMASWKSLSLQLLAVLLIVALLAQDTESHHGPLLIYKGGRRHGGGGGALATLLAAGAVAKLLQNNHHGKKFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QL81</accession>
    <name>A0AAV4QL81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_699251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006456">
        <property type="protein sequence ID" value="GIY10027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QL81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8352" checksum="17561BFB12AA1EC4" modified="2024-11-27" version="1">MRQYVVHSTTASIRTRQQSTEHVPALRSPPNPPFLQHPRNGCPTTVTGAFVGKFQDTQKEQLNEVGMFNVDAITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QM43</accession>
    <name>A0AAV4QM43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_266341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006358">
        <property type="protein sequence ID" value="GIY09302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QM43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11589" checksum="17BA30494C1C7C35" modified="2024-11-27" version="1">MPFGVLNKCYCYRKINTEKTCNEIKDYCGRNCYFFSLAGPDEGGAYYLFAITLRVGLGGQPADEWNLLLCCKLTRRKKCGWHLLHSCPKTLSLHERREME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QP40</accession>
    <name>A0AAV4QP40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_117201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006434">
        <property type="protein sequence ID" value="GIY09836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QP40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12469" checksum="4DBB295EE68849D8" modified="2024-11-27" version="1">MFVFKRKYVHIIKKYLGVDCVVPTVGGRYDVHLNARVKSSVYFDADDLQVRRGTWFFVITHRSINHIWKKQHKCLSNITLTVLILDNGKDDLIYLVLVVLYLNMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QV34</accession>
    <name>A0AAV4QV34_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_82781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006726">
        <property type="protein sequence ID" value="GIY11951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QV34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043472795" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="7966" checksum="6B40A4E6D06AB524" modified="2024-11-27" version="1">MMSNKTNTAVLGAWTFFVSAHAIDVCGINGLPLTPNSIHVLGTISEIKIIATSWNLYILGCKRGKHGKYHLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZS1</accession>
    <name>A0AAV4QZS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007176">
        <property type="protein sequence ID" value="GIY14985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10112" checksum="633DB34279076F5F" modified="2024-11-27" version="1">MLINMKKNSIHIFHKYLRTAWTGSFSPSSDIRVKINDGVPMIGMRTFQKTIGRYFDRFGATNNENIRRNPSFSRSTEETLLVALTWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1L4</accession>
    <name>A0AAV4R1L4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007053">
        <property type="protein sequence ID" value="GIY14267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1L4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20551" checksum="CD798210F54B275A" modified="2024-11-27" version="1">MHRLLEICLLAGLNENNELKHEGDIALKMEVKILKVLHFLDRKEQPIRGHRSHQLSTLGAIQAACNSPSDADNFFYGQSRSRGHFRRFTALAYYPKFTPMQINKELVTIAHNNIMGFLNLLTTSPRQTVVLILRDLQRVGRPVYAILPPPENIFRDPITNYFEFPVLSGFMGARHPTNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R227</accession>
    <name>A0AAV4R227_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-directed RNA polymerase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Polrmt</name>
        <name evidence="4" type="ORF">CEXT_412091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007252">
        <property type="protein sequence ID" value="GIY15604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R227"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="3">
        <location>
            <begin position="373"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY15604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="836" mass="97449" checksum="A35EAE5D0BD7F29A" modified="2024-11-27" version="1">MKSLYDSKATINFCYFKSWKCCRCSYKFCGNVEKKAQFSTALKTKIALEPEISKKKNKVEFKKEYKELFKLLKARECSLVNKTVLDRTKVCKNASDRTKNFKISENFTDLCNKENISQSELLEKPKNHEITEGIYTVKFTKPKKKKASSKKDSPDSNEENAKKLKRKKKKLSLKQENIKQVTKYSYDVHALKSYVEISINANEVEKTQIYLRKKMMSLKKKYKIETLGVDLYNLLISGWAKKGRLDKIKEVFSFMEEDQVSPNLQSYVGYLEGISNCKLKDINQMQQVIMDMKKKKNLCPEDILKKCVFKGDQREKVIEVLGFVGVDVFSDPIEIGDAYSCRLLQKLNAKSFGRGESFPNFGFQEKDIDSISSSQLEMESRFQLRIKSVDARTYLEKCENVWREEFTKSINKFKIEEKGSHAQNFYREDSIYPYISVIDTNILVNLMLQQVKALAEMGEFYNPSEKFIFKELGIKVMNHYFIWLNKTNKITDKVLLIYKEYLQYFLDKKLLAKYTPREYWEYLKQQNSKGPTIDITFTPWPHGVQVKIGSKLYSIMLQKVTFDENQVKKKIQQKFLTPGFYLHCESGFIDGEFRLSRNIGTHSLLCKLYRDAKLDYLEFDATLIPMLSPPKPWVKYDSGGFLITSTPFIRFNENAMHLNDFYSQVPPKNLNPCFDSLNSLSICPWTINKPVLDLIIDVFRKGGDEILDVPLNPNTLPPAPKVLSSMTQQERIIARGKKQEIRKKKCEASSLWYDCLYKLSIANHFRDEVFWFPHNLDFRGRTYPTPPHFNHLGSDLIRSILLFAEGQPLGKNGLDWLKIQLINLTGLKKEILILYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4F0</accession>
    <name>A0AAV4R4F0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_658401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007200">
        <property type="protein sequence ID" value="GIY15132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4F0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17307" checksum="E7C31532D970B5BC" modified="2024-11-27" version="1">MGIRIKILIIRKHDSGIETCRNSRDHLGWPPPGLIYALITNSRKTYFVLEVCSGRGRVEERLVRGRVCACNGTFHPRVCGRRRFTNLGRKDNGCHDRLSHETVTSNSSVSRVSQRYGTKIGYSHHLKIISTNNNILGFRQRNTQRAFHNAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RIG6</accession>
    <name>A0AAV4RIG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_92461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007866">
        <property type="protein sequence ID" value="GIY20304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RIG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9930" checksum="5B6ADAB79A91076A" modified="2024-11-27" version="1">MVFVWCPIKFEKLKAAFSNASAKTGLQNLVRANFDVEDAPFSESPIEVDKGKIKKKKLLNRIDVSFHLERQENYPYLKRIVTGDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RM58</accession>
    <name>A0AAV4RM58_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_462761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008035">
        <property type="protein sequence ID" value="GIY21587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RM58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF4">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13655" checksum="403DD42781E8595C" modified="2024-11-27" version="1">MYPGGTAIFIKNHIPHHNIPSPTLNTVQTTIVQLHNHNPFTVIPTYIPPQRKTPTYPNRNFFPLQDLTTLHNTFNSYFMGGDFNSHHRHWNCSRANTFGKHLFKFITDNTIYTLQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RML5</accession>
    <name>A0AAV4RML5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_425131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008134">
        <property type="protein sequence ID" value="GIY22319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RML5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10794" checksum="E3E3AE29F70EE8F6" modified="2024-11-27" version="1">MDALLQKQTRNSPPKAKSGRGFVGTFFLIKATLRVAQIIGALLKGSCLLIGNWLHRGHSYRSSAGTHQVDKLALEGEGGSFQNVKVKEPENDLQSTARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUN9</accession>
    <name>A0AAV4RUN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_223071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008352">
        <property type="protein sequence ID" value="GIY24101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12312" checksum="E8B1EEC70A3085F2" modified="2024-11-27" version="1">MQEFNPDCDSSETMVIYLERILQITFSLLDNVDWGIRDQRVQPLEEECNYAHLAFANRIQRGHLRMESGRFSYSVKINTKDIQSAFTYHNTYNLHHHTSLNYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2B4</accession>
    <name>A0AAV4S2B4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_83191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008852">
        <property type="protein sequence ID" value="GIY27790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2B4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="8013" checksum="87A5E498286514CA" modified="2024-11-27" version="1">MGGPEPGVIRGAGSGVMGGAGLGGAGSGVMRGAGLGGTGFGAMGGAGSGVWRGAGLGGTGFGAMGGAGSGAMGGAGLGGGGVGPGYWEVLDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S653</accession>
    <name>A0AAV4S653_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UBE3C</name>
        <name evidence="7" type="ORF">CEXT_257461</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01009024">
        <property type="protein sequence ID" value="GIY29110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S653"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="6">
        <location>
            <begin position="1"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY29110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="36393" checksum="01AA2EC09138F9BF" modified="2024-11-27" version="1">MDEVGIDGGGLFREFLQELLKTCFDPNRGFFKTTHDGLLYPNPNVQRVTPDFGRHYFFIGRMLGKAIYESMLVELPFAAFFLTKILSRHSTSDVDIHHLASLDPVMYRNLLFLKTYDGDVADLGLDFTVMNSEFGENEVVELIPGGANIPVTESNRINYIHLMADFKLNRQIKAQCQAFKEGLANVIDVEWLYMFDSNELQILISGSQTPIDIEDLKAHTVYAGGYSKNHPVICAFWKVVEGFDERQTRQLLKFVTSCSHAPLCGFKELSPTFCIQNAGREVRLPTASTCMNLLKLPEFENEEVLKMKLSYAIESGAGFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8U4</accession>
    <name>A0AAV4S8U4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Cyp1</name>
        <name evidence="2" type="ORF">CEXT_339171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009293">
        <property type="protein sequence ID" value="GIY30923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000029">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="1">
        <location>
            <begin position="52"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="20159" checksum="A1404F0BD790D2E8" modified="2024-11-27" version="1">MALTHVFQKLIPLSSNAIFSTSRHRALLCVNQVSKSLLCKSFSSEMSKPQVFFDVAADNQPLGRIVMELRADVVPKTAENFRALCTGDFTRGDGTGGKSIYGNKFEDENFILKHTGPGILSMANAGKNTNGSQFFVCTAKTSWLDGKHVVFGQIIEGMDIVKKIESYGSQSGATSKKITISNSGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9H9</accession>
    <name>A0AAV4S9H9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_81661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009207">
        <property type="protein sequence ID" value="GIY30310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9H9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9142" checksum="2ECE2CE8B183CDAF" modified="2024-11-27" version="1">MLNAVSTIMYFTVPRIKTQGLESQIPWIHQGAIRVNLLLIRSAVQIPLPFENMRACSAFYREIQLWGRDQWIIAKSSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SB88</accession>
    <name>A0AAV4SB88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_286611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009153">
        <property type="protein sequence ID" value="GIY29921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SB88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11116" checksum="04D7A066D6857084" modified="2024-11-27" version="1">MLTTDVHCGTLRRRGFPRPMLFTAPAVITTTTTTTTFHHHHDLLSLSCPCILLLGNLSWWKFQIGLSDLTFNMRDIDDSGYRTLQTPSQTDPGELLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGY1</accession>
    <name>A0AAV4SGY1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_164561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009605">
        <property type="protein sequence ID" value="GIY33214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGY1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="10165" checksum="ED40A90F9C8A411D" modified="2024-11-27" version="1">MIHSYKKNKLHHFENFKEAAMRFPAQRLSCRWFYIKRNNLWKPQGKISALTFNFKCNFSNQPLPSRPPSCKMLRFVSCTRDKHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SL76</accession>
    <name>A0AAV4SL76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_514911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009656">
        <property type="protein sequence ID" value="GIY33566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SL76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12364" checksum="DF9C8224FF6DE713" modified="2024-11-27" version="1">MMNLLEKWKRGVPNCPCRTPTYLPSFRFNCRAADLHLNPHFGISLDVCLFLLLPLRKMSLTPPPHLSAGMLTCRCLSSELLFPDLINYLSRIERWHPVLEIDVQTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQ99</accession>
    <name>A0AAV4SQ99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_127891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010016">
        <property type="protein sequence ID" value="GIY36154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQ99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12736" checksum="B9A8EE529C032AB2" modified="2024-11-27" version="1">MPYIKLPQHTLPTPKRRLRFTTNRKNKNKAEGISNANIDSYTTETHGIRILHRGNRKRYIRKDSGLYCLNIFQLPQLRGSDNNMAQFVAQGIFGYVYLKLTGIIWEILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SR39</accession>
    <name>A0AAV4SR39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_221877_1</name>
        <name evidence="1" type="ORF">CEXT_285981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009832">
        <property type="protein sequence ID" value="GIY34922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SR39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17177" checksum="DA8375645BEA753F" modified="2024-11-27" version="1">MSIHVFCDACKTSYATCIFLRNEFQDQVTCQLLQARSRVAPLKNITIVRLELLACCIGARLADTVKKDLKLEDVDVFYCCTFTDFLDDVHSANQSAVLKNSAKKERKEKISRKKGKERRKGIGCLRKWVALQKLRLSSVTRRFSSAKDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SV89</accession>
    <name>A0AAV4SV89_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Galectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_815881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010142">
        <property type="protein sequence ID" value="GIY37214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SV89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17169" checksum="7D23E0B19B574794" modified="2024-11-27" version="1">MVSGEFQQHVFRYQVLWNTLCAKSIPFAVTLKTILSMEATTTVSSSSSFGIWLSCSVISMDRCKVLVHMPTVELNGFGRIVLSSLRANDFEVEFHSQGFQSDRYLFHHVFVVKFGHYQLQDDEAGVDVMVAATGRKRNHVIVPVDIGQQVVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVY6</accession>
    <name>A0AAV4SVY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_551511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010173">
        <property type="protein sequence ID" value="GIY37454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8278" checksum="CBF90718FD19E2AB" modified="2024-11-27" version="1">MGGMTGLPNHLLFGMGRRPTPRQFTSAHTPEWNSQRFFWRNVVGWGGIWDGGASCKWDERRSFGELPSHTCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY48</accession>
    <name>A0AAV4SY48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kinesin-like protein KIF13A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_15533</name>
        <name evidence="1" type="ORF">CEXT_502271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010383">
        <property type="protein sequence ID" value="GIY38970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9597" checksum="999CDAC58AA0DB5A" modified="2024-11-27" version="1">MAALEKQHEEDKQIALDKQRQMYERQLQILRNQMSPGTPYSPYPPFDLLGLGKYTPAGTPTSNVQSRMERWAQDRDELFKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYG7</accession>
    <name>A0AAV4SYG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_593921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010179">
        <property type="protein sequence ID" value="GIY37520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9666" checksum="4F6B9AFF8B28F7D2" modified="2024-11-27" version="1">MSFNAEKSTFILIPLLCPGSPSTRPSSRLKKVLQSNCLALPKAIHLPATGQTLYISTFPRMLSIAIALICFIRYLPIKLCLIGRLGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYP7</accession>
    <name>A0AAV4SYP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_408551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010082">
        <property type="protein sequence ID" value="GIY36738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9903" checksum="3B6BC1A61D8A5C71" modified="2024-11-27" version="1">MSINLIQSYISETATEIEPITGFESQVVVAHLHNPKRGIESQVVVTHVHILDISVNSNCNRARKWIRIVGFEEFGLFEQVDSVRKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZK6</accession>
    <name>A0AAV4SZK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_346041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010430">
        <property type="protein sequence ID" value="GIY39220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="20088" checksum="922FB4D6090E9697" modified="2024-11-27" version="1">MFDEVRGLRRLVISQKSTKKNNSFGLRIDYAEVLMILQNRHSELMEKSCLVHEQKIKARSIACNSLFIYYLTFSLFLPPSRKPFLSPWLESTKNNNSNNKRESKLFPYTIRHNSKRWEEVKKKKATENGRTFFRQSLCLQRNIPSFLLTVISGRVGKGRCKEMVGWGGGILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0M8</accession>
    <name>A0AAV4T0M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nephrocystin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nphp4</name>
        <name evidence="5" type="ORF">CEXT_704422</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010485">
        <property type="protein sequence ID" value="GIY39589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904491">
        <property type="term" value="P:protein localization to ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058687">
        <property type="entry name" value="Ig_NPHP4_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058688">
        <property type="entry name" value="Ig_NPHP4_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058686">
        <property type="entry name" value="Ig_NPHP4_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029775">
        <property type="entry name" value="NPHP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058765">
        <property type="entry name" value="NPHP4_C2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31043">
        <property type="entry name" value="NEPHROCYSTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31043:SF3">
        <property type="entry name" value="NEPHROCYSTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26015">
        <property type="entry name" value="Ig_NPH4_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26190">
        <property type="entry name" value="Ig_NPHP4_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26189">
        <property type="entry name" value="Ig_NPHP4_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26186">
        <property type="entry name" value="NPHP4_C2_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NPHP4 C2-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 Ig-like" evidence="4">
        <location>
            <begin position="327"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 Ig-like" evidence="3">
        <location>
            <begin position="479"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 Ig-like" evidence="1">
        <location>
            <begin position="579"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY39589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="718" mass="81080" checksum="B4DC5F4DC20B245E" modified="2024-11-27" version="1">MNLELHCPPQKNECMMQFLALSNICEYVEVPSEVFFTFQFYRFLPIKSECLLLKQLSENTDGNFPKSSMVYAFMKTPERGTIPGFQITYNVDPTELNKGEYKAFLQYLMKQILHIDMWNGKSLLYIGTVSLPLKYFCRQGKEAVVSSLELDIFNCEYADESLGQINIPTKASLGKLHLRVASIRHPLPSKALEAFEEKEDTSNSIIISSKVEETRTGIPPHVVSKAKRLAESNRELSQLLSTRRISDESKIMSPNPHLTEERRRKLARMDAVRNLENGHTTASNEDGMLSFFKERRQDLLSIETYIQKNKSELIQSFLHKSVTSEERIYPLVGTKTFLEFVIENPFQVPKKVEIIWKCPELCLVTDVKEWQALRTINSISQQVKPLLFGDSSQNIPTIQLQQNEKVHIPFTYQCLSVHTSQMDLAVSGHHFTAEILSSIPALNSLDSAIKVRFVTEDQTLLAVLNLTVQPLPPSFTHVFKFLSMEHSMFKKSIQINRDISSNEHIAVKCTNSEVVCLIQENQTLEGNVNLSIKAPTRAAGKCTEFYIFIYKDKYRIVPFQAWSISVCPLQRIDLSCVAGQLLRSSLLIRGTHATNLVRCSSNSKDLQLHPSESFVLSPFAVQELSMNIRCLLPGIKNNNGEPSLGTNTPIVASSLILPKAFRVQSISSASLSQKRLPNASRTPIRTRKSGSLCCILVIRICCSCARMNSLLQLESPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TA75</accession>
    <name>A0AAV4TA75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase HERC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Herc2</name>
        <name evidence="9" type="ORF">CEXT_386941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010835">
        <property type="protein sequence ID" value="GIY42322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TA75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF6">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DOC" evidence="8">
        <location>
            <begin position="49"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="7">
        <location>
            <begin position="247"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="7">
        <location>
            <begin position="299"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="7">
        <location>
            <begin position="392"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY42322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="470" mass="52261" checksum="C7678E6DEFEE51DC" modified="2024-11-27" version="1">MERVPGLSNINMCGGCQGLLLKGAWYKCRTCPNFSFCAKCYKSDRVHMHELYAVKETDICLSKPVSGFIEDWRKCVKNVAVSSRENLAYHLTDGSKYFWQSSGKQGKHWIRLEMQPDVLIHHLHMTVDPSDSSYMPSLIVVNGGPSLSSMKELQTIVVGQNCSTINLLCEQSEYYQFIEIYIKQCRGGGIDCRIHGLTILGRRKTEADDSGFYPYLASDEDTEVDNDLQATGGLKSASGEILKDLETKVYVWGLNDKDQLGGLRGSKIKLPVFSETLSTLKPISISGGSKSLFIISHDGKVYACGEGTNGRLGLGHSNNVSFPRQIATLSQFVIRKWLSILKEGTKEFILECHKKSDFKIQTTVVKGIDHHEEILFLKVKRGRHALALTVDGKVFSWGEGDDGKLGLGNRMSYDRPRLILALKSKRIRDIACGSAHSAAISSSGELYTWGLGDYGRLGHGDLMTKQSQKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TD25</accession>
    <name>A0AAV4TD25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_812191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011100">
        <property type="protein sequence ID" value="GIY44160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TD25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11259" checksum="7D21D7BFB07EE7B9" modified="2024-11-27" version="1">MRTGEQPSNNSIRAAAHARNNLVPHPYHWRVHCHARPSRRQGLAERGIIAPEIANGSRFLCLFKLALTGIEKGVAIAVKPNADAPKLNFLYEVINKLRKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMS3</accession>
    <name>A0AAV4TMS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_432521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011569">
        <property type="protein sequence ID" value="GIY47359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9234" checksum="862DC101D8E13652" modified="2024-11-27" version="1">MLDISESTDLSCPCYYSMEQFSDLFSFSFCVVMNLSSPGLETLPQPVCDSCNLRKPCFPIQVPFGKLEIESLWTGRNFVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVW2</accession>
    <name>A0AAV4TVW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_297831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011916">
        <property type="protein sequence ID" value="GIY49950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9649" checksum="8FF9760810FCEB49" modified="2024-11-27" version="1">MKCQKTNLLCEGTKGKSATVMPYKVTKGEYVTIMPYEVTIDKSTAALQYEVTKGESATVLSYEVTSEPATVLSYKVTRRIYYDYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZJ6</accession>
    <name>A0AAV4TZJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Parathyroid hormone 2 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PTH2R</name>
        <name evidence="10" type="ORF">CEXT_344361</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012026">
        <property type="protein sequence ID" value="GIY50807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017046">
        <property type="term" value="F:peptide hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050332">
        <property type="entry name" value="GPCR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620">
        <property type="entry name" value="PDF RECEPTOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111418">
        <property type="entry name" value="Hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="9">
        <location>
            <begin position="72"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY50807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="32243" checksum="74F992705559FB62" modified="2024-11-27" version="1">MNRELFGVDNIMTFELKEPSSKATASKLCSENGTWWVHPDLNQTWSNYSLCGNVVPFQDEGNVFVVHIPVGKEAISQAGYSVSLTLLLIACLLLGSVRRLRCPRNNLHLQLFASFILRAAVSLFRDMTYGSNINEGTALCKALTSVWQYCLMANYCWILMEGLYLHNLVFLSMFTDTAGILKYGILGWGLPLFFIIPWIIVKAILEDILDSRHHTDTSFYSKISFTVSSKKLSELFPLWKLSGIFLLEQPSMIYEEICNSLKVEENARGLPVRWQENNDAKSHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U0L9</accession>
    <name>A0AAV4U0L9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_110071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012094">
        <property type="protein sequence ID" value="GIY51319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U0L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="47" mass="5166" checksum="B5610C1DA9DEA6CF" modified="2024-11-27" version="1" fragment="single">MLNTQSEWNGLEDVLAQGFGSGKADSKSTHRSRTKCLSVYTGMGRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3D6</accession>
    <name>A0AAV4U3D6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_36641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012220">
        <property type="protein sequence ID" value="GIY52293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3D6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043663319" evidence="1">
        <location>
            <begin position="20"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11331" checksum="AB461B87CBDD4CF5" modified="2024-11-27" version="1">MCMLFFRFFVLALIAVASCFVDAGYNSYGGYGNYGYGNRGYGGYGLGYNQYGGYGGYGSDTIDMVDMEDMVLDTIDMVDMEDMVLDTIDMVDMDIIHTFKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3I6</accession>
    <name>A0AAV4U3I6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_417111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012216">
        <property type="protein sequence ID" value="GIY52242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3I6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18834" checksum="ED3E0DFD02586720" modified="2024-11-27" version="1">MARKPHIICFDVSSDTEEKTLLDSLQEQFSEGTECMNDFAIKHHYKSRRGVNWIIEVDPKIWSKVTASRKLNLEVLDEISNSDHCLWDTEEPKQQHQNRMSINQRNWLTSKKIISSIVRANSLLDTDNLNNSIGNIQSEIKKKLSRTITSSNYSSPKKTQSGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UH43</accession>
    <name>A0AAV4UH43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rootletin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CROCC_2</name>
        <name evidence="3" type="ORF">CEXT_70031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012854">
        <property type="protein sequence ID" value="GIY57057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UH43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY57057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="316" mass="37636" checksum="C6F6E0462F9E218C" modified="2024-11-27" version="1">MKKSQIIIRNNDLTNQVTKYSNQKKNIELELEQQNSLKLQEEKSDLVRELENQRSFVNNFQAQIKDLHELHEKYVDDVAKEKNAAQLKMQQIEQEYQLSLKNERHQHNIDIEMLTQEKEALRSRMVIAIDELFERHQKQQDELLNQHQEEIHSDYKEQIATLEHTIESLESKLEENEASYDNLKRKFDKSEQEHSILVEENADIMKRLKDDLNNMSAENSKKIKKFEEKIETLKKEKESLLTEIQHLELQLSSTQSEKKKIAQELLDKNSILKMQIEDIQQKLNEKDISTSRLQSQNKELKSTLREVEKSRQETKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULJ0</accession>
    <name>A0AAV4ULJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_150061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013096">
        <property type="protein sequence ID" value="GIY58736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9608" checksum="761F1927D85F41B6" modified="2024-11-27" version="1">MTLFEMITNRSSAFDWLWNDSIPSIDTSKTWNEDNKERHPFQDITCCLLSVLKFRSFKIYRDHLQSISDFILCYLKPGISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWI4</accession>
    <name>A0AAV4UWI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_193231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013574">
        <property type="protein sequence ID" value="GIY62093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12620" checksum="1D48C6FBABC0972F" modified="2024-11-27" version="1">MKRFMLMRADSVVVLDVAWKVWKNGRQFLQDDERSECPERICAGKIYFDKLHNRYNKTVQAKENTVCASGIPSGQTYVSGVSVFHVWSENGRGQYLAHYTNYCGWHVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UX87</accession>
    <name>A0AAV4UX87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_552651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013600">
        <property type="protein sequence ID" value="GIY62268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UX87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="266" mass="30036" checksum="A9A93274C76CA81A" modified="2024-11-27" version="1">MGRKKNSTSLQRALGNLVDLVSNAHTSINKTHFSWKYFTLRSAWGEESNLEGLSRKKENEKRKKGKERKSSATALAAKIHFSFPGSLEKRTRDIGTDGKKERREKPALSKRALGNLVDLVSNAHTQSIKHISPGNISHSAAPGAKKHIIRIVLKNHKCGNIKKRSHDRFQLVDPSPKQKARVNATKVPDVSISFFKWYGTVLPEGIAIPLKPLPIRGSKQLWVKEKVLRRGVFKLFGQSMNGFVKHSDVYPGQSFLLKIQWQRFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V009</accession>
    <name>A0AAV4V009_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_435591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013752">
        <property type="protein sequence ID" value="GIY63512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V009"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14963" checksum="634E60C27CC89296" modified="2024-11-27" version="1">MMTKFPNGYKEHCEVQYFLRRVILNLGNSLTFQGYWEIHCLFAAIGKSTFSAIPSLRSIWTRKALSLTYGMWSLILSPLELRPLGWPLIYLLSSARGNSRRVKQPPRCELKFYYLPPPHPLRSDSSRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1B8</accession>
    <name>A0AAV4V1B8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_306071</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the noggin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013782">
        <property type="protein sequence ID" value="GIY63755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1B8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008717">
        <property type="entry name" value="Noggin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05806">
        <property type="entry name" value="Noggin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349267" evidence="7">
        <location>
            <begin position="25"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY63755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12651" checksum="8824F452CEAF3AF4" modified="2024-11-27" version="1">MEYQTIVRCFILLTFCIVSTKCKGRRPSGSKIMPVLELMEPEGAIYDPSPEDIDESNLKKLLGSFFDPQVMSTEQPSAFALFPNGTVKLGLKKTRSGQLVPQGAPSSTSKECTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1L5</accession>
    <name>A0AAV4V1L5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_452841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013761">
        <property type="protein sequence ID" value="GIY63589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1L5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10488" checksum="092D6BE694C54923" modified="2024-11-27" version="1">MLILGRETNTSPNSNKTVLHSPYHPSSWTKNKGKTFSEILGANQFPAKEPNLAGTDATSNLQIPSPPRIEPLWCLSARACLSARGPRDTRYPRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2N6</accession>
    <name>A0AAV4V2N6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL31</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L31</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RpL31</name>
        <name evidence="6" type="ORF">CEXT_451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013873">
        <property type="protein sequence ID" value="GIY64392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020052">
        <property type="entry name" value="Ribosomal_eL31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01144">
        <property type="entry name" value="RIBOSOMAL_L31E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY64392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14400" checksum="3A042B67F1C8C92B" modified="2024-11-27" version="1">MAKIKSEKKGKSALSEVVTREYTIHLHKRLHGVGFKKRAPRAIKEIRKFAEKQMGTPDVRVDTRLNKFIWSKGVRNVPYRVRVQLSRRRNDDEDSIHKLYTLVTHVAVTTFKGLQTENVDVSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7A0</accession>
    <name>A0AAV4V7A0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014010">
        <property type="protein sequence ID" value="GIY65598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7A0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="210" mass="23086" checksum="6A5923A39F3BD870" modified="2024-11-27" version="1">MEGALPLPVTLAHASLCLPPVNQPAEEFLLEKDVSCMFPFVSQRRENSMQADSVEPQPAPIYPRGLKLAIPLRRLHHADSSSQPASAACCRHPKKCPIFPGSEIAVLRDSKGHDQAAHFGSGFNKKEHAQLEVFAAKCEIRLASLTLTGVIIVMTVERESEVIKGVVRLCCGYGTSLPEILVRMNFLDPKVRLTKRDVRLNDHLPCVESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAJ9</accession>
    <name>A0AAV4VAJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_553501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014185">
        <property type="protein sequence ID" value="GIY66995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10115" checksum="EB8D42BBB3019AF7" modified="2024-11-27" version="1">MEVTFFFTSPRMFSSSSKNFANNFFSNRRLPSIKQAIHQAIMRNGPCWCDVVCKDGKENLFRLNREEYCIEKGTSSEKNNKPLSLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VC26</accession>
    <name>A0AAV4VC26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_11421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014194">
        <property type="protein sequence ID" value="GIY67050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VC26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18910" checksum="F6ACDED73C280153" modified="2024-11-27" version="1">MDKCLVVSLSVVHRVCQEINNRFLYDSEEILNGQCPYNNFDALLAEFLHLQPTPQFLRSRDPWLDKPLSHSTCALASWFFATIIPRITITLSPVFAPGFSREKFVRLALSPLPDEQGLSDEQSCPKLLFLCDSKAFARDVFVRENIYLTVYKQDVQVWYNSGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCF8</accession>
    <name>A0AAV4VCF8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_140651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014308">
        <property type="protein sequence ID" value="GIY67987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19896" checksum="C16ACDEC3B000A86" modified="2024-11-27" version="1">MYLLPSLQSLQLSAYVGISRLAALLGFLKPDVFGAEVPKVVELRQLSHLCNPSHMNAVFHEHLLLNTSFNQMNDVFNEKSFPTNISVSVINSRKFEKIPPQLQKAWQQSQLYLRQSLHPTCTYYVADGSSGELYNQPGMVIRRVQQLVYKWRINYHTFPTVHTFREQETLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VD18</accession>
    <name>A0AAV4VD18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">THAP-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_42702_1</name>
        <name evidence="1" type="ORF">CEXT_16171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014279">
        <property type="protein sequence ID" value="GIY67754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VD18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="239" mass="27511" checksum="438425C28628102D" modified="2024-11-27" version="1">MCSKRRRLKGCAVPSVFPECELKHKFVENKVIEFEIIFKKDGEESFCSNKNYGLQNNLLNSYLETVVTKEQSLSKDISTESQESENYYTLDSTEAESSVITEREQFSELIFDSSDLDLAYKSNYVYDNVKIKDDIKFITPLNNNVEGLKRISAQESNLSEFTIFGLYIASQLQQLPIEEAYALKEKIQNLLTQSCPQSLKEPSFFSYVQTSDTDLKSDSFLKNYILNHLLLKKVCNESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGM2</accession>
    <name>A0AAV4VGM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_772341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014510">
        <property type="protein sequence ID" value="GIY69263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13845" checksum="79462414C9520226" modified="2024-11-27" version="1">MVILRPLPAHSWVNDRCRHFFYCHIFKLCPLLCHRCGKLVQWSPPHTETEFMAFGAPIQKKRPSRGVRRLEICLFQKHGYPFSLSVCFCLSFFSNISENGAVWIERNDFPPSNYVRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVT8</accession>
    <name>A0AAV4VVT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">G-protein coupled receptor 52</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Gpr52</name>
        <name evidence="12" type="ORF">CEXT_334651</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015212">
        <property type="protein sequence ID" value="GIY74397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22752">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="43"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY74397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18245" checksum="7E1F93EC74A69CBB" modified="2024-11-27" version="1">MLGHSSDLFLSQSEAYDIEAEASPEQVVEAVVILVICVAIVVTNVLIIWAVSSSPSPKDAIDLYVLSVAVADLLCGVCIVPLSIYPAFVKEWVYGNLICRLTGYLGLTLWSVCLYTFMWMSVDRYLAIRKPLRYDVIQTRTRCQCWMVFTWLTSLFLCSPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3U8</accession>
    <name>A0AAV4W3U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Laminin subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_12564</name>
        <name evidence="4" type="ORF">CEXT_506301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015497">
        <property type="protein sequence ID" value="GIY76544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Laminin EGF-like" evidence="3">
        <location>
            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY76544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="305" mass="32326" checksum="BC5D24E9CAD9E1ED" modified="2024-11-27" version="1">MVIWWKPFSPTSFIVASACSESDGPDVTHGNCTLIFHVYTTCRRPWKCCWSRRPPAPCSCPGSPPSPKGRNLKLFTYSLTLTPLTHYGGTRTGEGVLLPPSITSKLVGGLTEGDALRGPAVRHLRGPQQEAEPRRPGQGDRPQVHRVRAPGGAAGHPVGDDGLPPDEPPCNCSDTGMVACTRRPGFVECTCQPGYGGTWCEECAPGNFRAGKECVVCPCSNLTSTAECKMEPSGQVSCVQCLPGHRGSLCTSCSAGYQWTEERCAPDCLSSSLCARHRDAPDARTASSLTTSSPPPPTGPSPTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBX5</accession>
    <name>A0AAV4WBX5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ceramide glucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CEXT_409002</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1&lt;-&gt;1')-N-(9Z-octadecenoyl)-sphing-4-enine + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:70247"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:77996"/>
            <dbReference type="ChEBI" id="CHEBI:189081"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:70248"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>UDP-alpha-D-xylose + an N-acylsphing-4-enine = a beta-D-xylosyl-(1&lt;-&gt;1')-N-acylsphing-4-enine + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:70243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:189068"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:70244"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.80" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01015798">
        <property type="protein sequence ID" value="GIY78795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008120">
        <property type="term" value="F:ceramide glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006679">
        <property type="term" value="P:glucosylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02520">
        <property type="entry name" value="Glucosylceramide_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000041">
        <property type="entry name" value="UDP-glucose ceramide glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY78795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="395" mass="45278" checksum="76D06908C329153F" modified="2024-11-27" version="1">MVLLFYTLYGFAIFFFGGWCFVWLLHIIAILNGKLKLHRKPQLPSPEVPLPGVSILKPLTGVDQNLYTNLESFFTMNYPKFELLFCIEDESDPSIMLVKKLIEKHPEIDASIFIGGDKVGVNPKINNMNPGYEAAKYDLILVSDSGIRMKEDTLLEMACAMSENVALVHQMPFTCDRNNFPSVMEKVYFGTSHARIYLAADLFRINCPTGMSALMRKKLLDEVGGIKAFGQYLAEDFFFAKSFTDRGWGIRISSQPAWQNSGICEIKNFNNRISRWAKLRFAMVPYTIVLEPLSECMVLGACAAWALNVLFQWDVFVVYLVHILAWLILDWALLNIIQNNSLPFSKMDFVIAWTFREVGAFYHFCLALFDPKIQWRTRTFYLRWGGLAEEVSPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEL0</accession>
    <name>A0AAV4WEL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_492881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016065">
        <property type="protein sequence ID" value="GIY80966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8529" checksum="21E480BDEDAE1C5E" modified="2024-11-27" version="1">MFLGGRCFHLPQSPSNRCPPVGAGDEGGLSKMTHVVRNDELGGVQGLGDERGLSKVTYVVRNDESEVFGGKEEVYFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIH1</accession>
    <name>A0AAV4WIH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_591641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016199">
        <property type="protein sequence ID" value="GIY82029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9284" checksum="E231029DBD117673" modified="2024-11-27" version="1">MCVARWGDAGLLSPWPLSVERVVVGLNGALILLGTGRLRGVLDRDHAVLIAAAIIPVPRFVLIYSLLPRSTSGTREGIPWHCGCLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRK1</accession>
    <name>A0AAV4WRK1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_199261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016659">
        <property type="protein sequence ID" value="GIY85477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043865005" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY85477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15636" checksum="37C7CC74B56E2A76" modified="2024-11-27" version="1">MVEKLTLSLILSLPLPLEGESPKHKNKQNKTKAPERKKKESKCEFQLPFSKCHRNVDLSCSWKNSPSPEKGGRESKFGKPGMQRGRGLSSLFEINFATGRSFPSREIIAGIKNTPDTNIRSMFRCFVMYKAPMRFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTK1</accession>
    <name>A0AAV4WTK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_469361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016584">
        <property type="protein sequence ID" value="GIY84873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="18275" checksum="39C0F4B371ED55FC" modified="2024-11-27" version="1">MLQKKSIGHRYLEPEVSEGSNFSTDTRGSKEETEGGGENLPFTSARAEGLKVEGGPKINVCRRNEDADGGATGGSQRSLPRHISLVEHSKTHSKGMHTFRGCGTEQRILKGLGCFKTRVAGDLVTPKDGCIDIDQSTDSARGRASPARSPQPRAPCRGKCPSRKKDPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTZ7</accession>
    <name>A0AAV4WTZ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_85201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016686">
        <property type="protein sequence ID" value="GIY85748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18282" checksum="885C520C140402FE" modified="2024-11-27" version="1">MDPAFIRKEDDARGKMIKHIIAQRQIKSNIGLIHSLLSDMNYSNSLACTNIQNVSIAITGNMACENPSWINPCGLTTDEVDASFDNTSIDDLNKRIVDSAEVFSSQLNELRNYMIKTFPDIDEESLISHEFSFLKTQKVLQRFMRISSACFRNVQWLWIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7Z8</accession>
    <name>A0AAV4X7Z8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylosome subunit pICln</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CLNS1A</name>
        <name evidence="9" type="ORF">CEXT_53661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins. Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pICln (TC 1.A.47) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017400">
        <property type="protein sequence ID" value="GIY91282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7Z8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034709">
        <property type="term" value="C:methylosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006821">
        <property type="term" value="P:chloride transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003521">
        <property type="entry name" value="ICln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01348">
        <property type="entry name" value="ICLNCHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY91282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="25378" checksum="EBBF491960E82FB0" modified="2024-11-27" version="1">MSWQQTLVHSIVDINNFLGKKHILKMVFLKNFPAPTEGIHHIEPDTKVYFDKECLGKGTVHISENVLCWISSTGSGFSIQYRSITVHAVSMDKANFPEPCIFLMTDGKIKLEDLSSSETVQLEGAMNSMNVNESDGDGDVIDDEEMDPNLLYLVPDNKNSLDAMFKAITICQNLNPEESLEDDEDDDDGFDNLSFDIQVTNGELEDFENGDEEFSDMDEGQFEDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIP6</accession>
    <name>A0AAV4XIP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_555801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000454">
        <property type="protein sequence ID" value="GIY94930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15380" checksum="04A45EDD45418800" modified="2024-11-27" version="1">MKKDSTSQSHFSTHLLAPFEIISEENTFHLIYLLFSNRRRNQKLQCLRSISSDEAEIEPFITFMIFVEIQGRNAFEALLQVRSTVWKRAPFAGASAAGCLQTKKWAPGTATAFAPSATHRWSLGSASESPPTPEENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSS8</accession>
    <name>A0AAV4XSS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_270171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000702">
        <property type="protein sequence ID" value="GIY96798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="232" mass="28283" checksum="EE424A5E2D97DAA7" modified="2024-11-27" version="1">MEFLKKEINEEDIEVNFIKFQELNHRYRKLIQEFKALPGIRNFKNIKWMNAVKLYRMVLLDDKCLMKAMRKYHPLDTLFKNNIDTLDSFEFLEKVFKEVNEHYFFEKICMWHDDVEKYRYDPGTQSFVLHICDYMLEELIHVIKYELIADCDVEKCMSSMKQYKNASYEDRKKLLKIKKEVFNEERCREQCGILLQEIIERKLSFLEMLPLSSHLNIKREGYIPKVLRMGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT27</accession>
    <name>A0AAV4XT27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_170981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018280">
        <property type="protein sequence ID" value="GIY98317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10781" checksum="411338F217C12121" modified="2024-11-27" version="1">MASMLCWFLSYGSYREGSGVSCSYRRSQEPLEQASSSSKWMTFPRTKICPKDSGVSSEHHLPHVGGTSTSGTPYSIPFPDLNSPGSPDPKQEFQIPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUF0</accession>
    <name>A0AAV4XUF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_616111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018164">
        <property type="protein sequence ID" value="GIY97489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14526" checksum="A2BF1BCAB0F94C2F" modified="2024-11-27" version="1" fragment="single">SILETVRFELSPPLRRRVILPRDPCFPESSFLLDPRLWPLGVILHESPRTAGCPENPSSASGLQFAWGCFRRPCSEMSEKNNCVQEIQFGCETKTRFKKWHSSGDSEKAVSNEPFDVSLSNENELRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUH5</accession>
    <name>A0AAV4XUH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PGBD4_103</name>
        <name evidence="1" type="ORF">CEXT_328321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018345">
        <property type="protein sequence ID" value="GIY98845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8655" checksum="4B91A1FCB31BC117" modified="2024-11-27" version="1">MLSTVNGGKNTQLEFRLDLIDRVIEKYHSGLNFHRGRPGSEPNPPEIDRQTLLEIIAPQIKTETCKTIRGVLLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVX9</accession>
    <name>A0AAV4XVX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein 36</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ttc36</name>
        <name evidence="2" type="ORF">CEXT_269281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001021">
        <property type="protein sequence ID" value="GIY99206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038906">
        <property type="entry name" value="TTC36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405">
        <property type="entry name" value="CDNA SEQUENCE BC021608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16443" checksum="7F16732F8ADCDDEA" modified="2024-11-27" version="1" fragment="single">EEELTNTVIEAKRLELEAVKKAETGNVEEAIEILNHSIQLAPRRPSGYNNRAQAFRLKGNVHVVTALLDLNNTIHFSGGKGKSACLAYCQRALIYRHQNKQKEAVADFEKAAELGSAFARSQLTLMNPYAALCNQMLRKVISQYQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y522</accession>
    <name>A0AAV4Y522_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_484521</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018759">
        <property type="protein sequence ID" value="GIZ02138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y522"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001485">
        <property type="entry name" value="Krueppel-related zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001370">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF142">
        <property type="entry name" value="ZINC FINGER PROTEIN 384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13465">
        <property type="entry name" value="zf-H2C2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13909">
        <property type="entry name" value="zf-H2C2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIZ02138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13803" checksum="950E7CFAAAFCAF1B" modified="2024-11-27" version="1">MVRYFTDAGINSIKTAKRYQCFSCGYSTSRSDDLKKHIRIHTGERPFRCTFCTKTCNEKGALNKHMRIHTGERPFKCPKCDKTFAWSSNIKKTRDDSSFRMVFAQSFLNHHFNFDISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6A2</accession>
    <name>A0AAV4Y6A2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Melanopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">OPN4_0</name>
        <name evidence="18" type="ORF">CEXT_144681</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001379">
        <property type="protein sequence ID" value="GIZ01976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060170">
        <property type="term" value="C:ciliary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22752">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22752:SF10">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0807">Transducer</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="17">
        <location>
            <begin position="74"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIZ01976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="19601" checksum="513220239B712613" modified="2024-11-27" version="1">MEATMEDDDSTDVSQWVDDGDSIHNSTTVATASTQSGILTQTFEPLINSSSNDELLRYTQFTILSLITTVGFVSNVLVLLLFYKKPTLRTFSNRFVLNLSISHFWQCVLILPTTVLSIAADRWIMNEIACYISGFLYTTLNITSVLSLLLIALDRNCAVNSPLHYSMTITKNALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7M7</accession>
    <name>A0AAV4Y7M7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_28911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018876">
        <property type="protein sequence ID" value="GIZ02914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21892" checksum="753F5998FB9A1087" modified="2024-11-27" version="1">MLKKVSSLFTSRVWPVFLGRYQSPPMRWERSLSLINTSIDQTPVPLRLIRAIKPDSWGSKGAHDGLQPLHPESDRRTKTVQGREILLDVFIRHVFRERGELADFDDFVSTLYLLIFLSFRLSVCNLFLLPLSFSCFILFLSLLLLLCVHMIKNEKRAKNIHILRLVGKSGFSLEEYRKSTSVRRLKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7S4</accession>
    <name>A0AAV4Y7S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_35231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001464">
        <property type="protein sequence ID" value="GIZ02486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8160" checksum="12A48E9DC082F75F" modified="2024-11-27" version="1">MSEEKTPWPKRLGPEFHETEKGLRTDSRISLRGRAESAGKMTKLDHLGEVHHRQQLSPSRRLFQSCFFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBW4</accession>
    <name>A0AAV4YBW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_446181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001732">
        <property type="protein sequence ID" value="GIZ04414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9738" checksum="B9E7708FA6E2DD19" modified="2024-11-27" version="1">MNSLNHHHHHLVAQPDDDDDDITLFTQLGSRFYGQLHNLPSPARSYTNDFHGNAHPHNPRCTPRKIQQGLEIRGGGRVQKKNRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFG6</accession>
    <name>A0AAV4YFG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_171221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019188">
        <property type="protein sequence ID" value="GIZ05004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15367" checksum="0E249077FB918057" modified="2024-11-27" version="1">MTGVITAKPPSRRLFGRHKLKLETSQQLRGWWGGDFRIRYVSGVPRCYWRQAISLQGVPEPSLFLDILSARQNECSNSENNCLDRDRNTSPSLAICSAAILFSNSSGDFLSVFAENKKLSLRDWENGFCFLFFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M681</accession>
    <name>A0AAV4M681_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_147391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019438">
        <property type="protein sequence ID" value="GIX67853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M681"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11649" checksum="950B6F5F9976D74A" modified="2024-11-27" version="1">MLFSQTGYKLMTKWCDTILKSKLNIKKQKSTSGGKNPLFLLSNPFHPQTHTNPYLPNPLKATRDHRENQLYESERICEIGSPIYFSKTNPAVYFFPRQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6R0</accession>
    <name>A0AAV4M6R0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HNAJ_LOCUS7387</name>
        <name evidence="2" type="ORF">CEXT_278811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019446">
        <property type="protein sequence ID" value="GIX67930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052560">
        <property type="entry name" value="RdDP_mobile_element"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688">
        <property type="entry name" value="ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24801" checksum="9F245EE5CE0CF484" modified="2024-11-27" version="1">MFKWIRSFTDQRICKIKFGNSLSKCYNLQTGLPQGAVGSCSFFNLYINDLVSALKTVKDVDCSLFADDLVIWTQAPKVNAKSLIENEINKALDILSDWCIKNNMTVNLEKTATQTFSLAHQTLLPDLKYRDVALIHSNKFNYLGVTFYNKLNWKSHIESTSNRFLKRVYILKRLAGSLWGCDRSTLNVTYKTFIQPSITYYCEPLIAEMRKYCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7U2</accession>
    <name>A0AAV4M7U2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription factor BTF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">btf3l4</name>
        <name evidence="5" type="ORF">CEXT_374871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAC-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019441">
        <property type="protein sequence ID" value="GIX67890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7U2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22055">
        <property type="entry name" value="NAC_BTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000001">
        <property type="entry name" value="Transcription factor BTF3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAC-A/B" evidence="4">
        <location>
            <begin position="116"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX67890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="239" mass="26947" checksum="05092ECDF9B488C8" modified="2024-11-27" version="1">MILLIAWQGHFEYIIFSAYISHLDQVGIHQKEPLYTTESKVVKVPSTYYKDLLNFRSLKINYSSINVRNKISHAYIDHIHSTWMNPERLSKLQAQVRIGGKGTARRKKKVVHRTATTDDKKLQSSLKKLAVNNIPGIEEVNMIKEDGSVIHFNNPKVQASLAANTFAITGHAENKQITEMLPGILNQLGAESLTHLKRLATLQNPTGPISEQTNSGVDEEEDEEVPDLVENFFFLTIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8Z6</accession>
    <name>A0AAV4M8Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">lhx9</name>
        <name evidence="15" type="ORF">CEXT_72461</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019388">
        <property type="protein sequence ID" value="GIX67304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000027">
        <property type="entry name" value="LIM/homeobox protein Lhx9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF168">
        <property type="entry name" value="PROTEIN APTEROUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 10" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="13">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="14">
        <location>
            <begin position="144"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="9">
        <location>
            <begin position="146"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="80"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="243"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX67304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="34555" checksum="B79190E0457C25B8" modified="2024-11-27" version="1">MGTFRLVAVTNCSRCQGGIFAANMVMRVRDHVYHLQCFRCAWCNAPLESGDFFGLRDNLVYCQQHYDGAMAYEAPPLPLYGPPFEAPPPPQGRKGRPRKKKQAEQDMQKHVQGLSPIDPSGLSVHMGHLDGGARSPPPLSSSGQRMKRMRTSFKHHQLRAMKAFFNENQNPDAKELKKLASRTGLTKRVLQVWFQNARAKWRRNNNNNKQNPGQPGGMMGNEHSPNSQLHPMGLLGNELCSPDGVSSYSESSPVHSCGGVPSDGSLSTHVGQGQSMDFDSSNPLTPIINHHGHNPIHNGDPIMHMTSFQNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGW1</accession>
    <name>A0AAV4MGW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_759831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019779">
        <property type="protein sequence ID" value="GIX71707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10044" checksum="A57D3886B2724407" modified="2024-11-27" version="1">MPQKRKTQKKDPGALRARLRQQSNFVNPSPGKFQEVLCDLPEGSRKQMIGAATATPTQRQKEPGPNGVHPCRQSKRDARLPHRPTKTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJA4</accession>
    <name>A0AAV4MJA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_578741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002231">
        <property type="protein sequence ID" value="GIX71561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8456" checksum="344AFB649D8BE84B" modified="2024-11-27" version="1">MNIPRNSILLVKGIFFKFFQSLWKPIDVITRRLRRNVEVLRGLKMSFHNSQDPNNFGFLLHSFASILFKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MM04</accession>
    <name>A0AAV4MM04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_119641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019958">
        <property type="protein sequence ID" value="GIX73509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MM04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11084" checksum="5A21FF4B606D35F0" modified="2024-11-27" version="1">MIFKTNIKLIAIFQNKKIAQLHLRSSPSLHANRPILLLSPHISYTHHYRVHNASGGQRNIAAKLVERHNLSAVLGTVSRREKCYEKGMFLIPSRCKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNG6</accession>
    <name>A0AAV4MNG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">med15</name>
        <name evidence="4" type="ORF">CEXT_389882</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002424">
        <property type="protein sequence ID" value="GIX73551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048386">
        <property type="entry name" value="Med15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048385">
        <property type="entry name" value="Med15_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31804">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31804:SF3">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21539">
        <property type="entry name" value="Med15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21538">
        <property type="entry name" value="Med15_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARC105/Med15 mediator subunit central" evidence="2">
        <location>
            <begin position="235"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="ARC105/Med15 mediator subunit C-terminal" evidence="3">
        <location>
            <begin position="394"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX73551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="513" mass="55354" checksum="3DF6605F7A43B8C7" modified="2024-11-27" version="1">MTGAVPSANMGQTGGVNVGVSDPMSALKSMAGQGSGGTVTIQSQPGQTQMTASLLGSGGTMTAPPQPQPQIQVQSLGQGIAPGSGPNVVTSSINPQGMSPMVMQQTRFLGPGGVLTSQQIQQRPQMLAPNVQVLQKFRQQVPPPNVTSTQIMPNQGPNSNQSAVPSPASHHNQNISSQMVQSPAVYGQSPNSQIAPSPAGSYSVRTPGAPSPGSALNTPIPAGPAPSPINRNPQDDCYLEKRKQLSKYIDPLKKMITRIDKDENKKKDLNRMKNLLDLLTDPSRRCPMEVLIKCEHVLEKMNPSFMQMDLPTASGSALTTGPTQPAAFPPKTQEQNICQPLIDALQNISKSPMFNHILAKIFDPPLIALFGPTVRHLTPTPPKKRKLEEDSNEISDLLQGEIARLDQKFKVQLDPVQHFGSKTVNLICQLDDKNLPCVPAISITVPENYPEVPPQCYTTKDEYESTSILQKIQQILSTRLSTMPQKYSITCLLDTWEMSVRQACASNPVAVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPL3</accession>
    <name>A0AAV4MPL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_522681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002458">
        <property type="protein sequence ID" value="GIX73956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12422" checksum="808C27BF95D8F2E6" modified="2024-11-27" version="1">MIQYHNTILHGSQKILFYIGWDTNYTKQKNTRISKDNCKKTSSYWRSTINKLAEHIHLIRRNDTSLVLAASENGRPHKFECATDCSVSVSINNPFPVEEIPTNRKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTG1</accession>
    <name>A0AAV4MTG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BRCA2-interacting transcriptional repressor EMSY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EMSY</name>
        <name evidence="5" type="ORF">CEXT_201441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002577">
        <property type="protein sequence ID" value="GIX75276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.40">
        <property type="entry name" value="ENT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033482">
        <property type="entry name" value="EMSY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005491">
        <property type="entry name" value="ENT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036142">
        <property type="entry name" value="ENT_dom-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16500">
        <property type="entry name" value="BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16500:SF3">
        <property type="entry name" value="BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03735">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01191">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158639">
        <property type="entry name" value="ENT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51138">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENT" evidence="4">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="413"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="635"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="832"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="420"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="668"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="832"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX75276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="853" mass="91535" checksum="AA0BF8CD2041B61A" modified="2024-11-27" version="1" fragment="single">VEAYASMVTAFRAQGSLTKEKRRMLQELCSMLGISEERHKAEVRRVVNDEHLHTIAERLFGSNTATEWAIEGRRILPLVNRLVPQTVFTEIANTVASSQIARNASLPLPGKTGSKMSNGTETMACRKRKEHIISDSSISPQKMSAMDSHFFRSLHHHDCQNSGISEQVPDVSVSSENFPVSETGTPNSSSVTDSSLQRTISTVAPTHPTQAALTIAKSKHQILKSSSTFSNFDHLNSNLASKGVSLSPIPVISHEEHVSTASDVVKSLSDTKITPRPLSSLSSMKSSTIVIPTNLTSSSTSSSSDRISTSSSTISQNKYLSHIRTKPSGHTRQNLPAGLGIKLTPQSQISQRVTVSPKSSSVQVKPDNATIFTRKTTSVIFPTSMSSDNSTSQFPQTISNDLTITKTPIIKPSPKPESQAVVNQQSVSKQSTIGKNMPKTSTTTVTTSYTYATTTLASTCISRPLFSSKGGSKTLSPVIFNVATTSCAPHQTNMKTAAVIQSESTKPAAQLITKSTTIGISPNHLKINTANPQTIQYRNDGGLVRSARIVNISQPVGARLPCAISSSTFSAIGLSSSPTALRVTLPAGTLNTTNSIRVTSQTKPNVIVVHKAQMWPRQPTAAVFMSSVPSKKLSNDVQEAVTQKADKSKPSGIKPIPRAIIPPRPQSPVVSITPIKSSETNPVSQSSTTQLENSTSDTQNVKSSDNNNEMQCKKNLLADVMEASGILDGNTIDKSSKDKTSTIKSNKEISNMSNHQSIEIRVSEVCHTNSSTSDAISRLSESNASKVDITSNKGDSVLSIQIDRSGKDVSKQVPVEALPKDSENTVFLSSHSMNENLKSNMVSTSQKEVTKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUU4</accession>
    <name>A0AAV4MUU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Degenerin mec-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">mec-4_1</name>
        <name evidence="13" type="ORF">CEXT_704711</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020236">
        <property type="protein sequence ID" value="GIX76179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF300">
        <property type="entry name" value="PICKPOCKET PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX76179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16976" checksum="A48CB9213AB673DD" modified="2024-11-27" version="1">MWLPDPTLFIRNDLKTCDITNKTEMCCLKDVLDNMSQRGPTCYCPLPCTSVSYNAKLSRSLLPTQRMLKRMNGEFGENNDYIRVNVFYSSSEVLVYQQRGQWTITEALSFLGNEFGLWLGLSLMVVFEVLEKLAQFFKSTLTMLLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYK0</accession>
    <name>A0AAV4MYK0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Transcription initiation factor TFIID 18 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TAF13</name>
        <name evidence="11" type="ORF">CEXT_249461</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF13, together with TAF11 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the TFIID basal transcription factor complex, composed of TATA-box-binding protein TBP, and a number of TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Interacts with TBP, and more strongly with TAF10 and TAF11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020222">
        <property type="protein sequence ID" value="GIX76064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07978">
        <property type="entry name" value="HFD_TAF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000028">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF5">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00062721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00082869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX76064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14451" checksum="BE2070FC74C183F1" modified="2024-11-27" version="1">MAAATEDFDQFEDDLQESQEPQTGDKRKRLFSKELRCMMYGFGDDQNPYTESVDLLEDLVIEFITEITHKAMDTGRTGRVQVENIVFLVRKDARKYARVKDLLTMNEELKKARKAFDEVKYASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6B4</accession>
    <name>A0AAV4N6B4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPIB</name>
        <name evidence="3" type="ORF">CEXT_721821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020563">
        <property type="protein sequence ID" value="GIX80026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6B4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043708227" evidence="1">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="36"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX80026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9762" checksum="8E1A409A30F447A6" modified="2024-11-27" version="1">MLRLVLLSVCLISSFSFGYAQEEKKPKGPKVTDIVYFDITIGGEPAGRIEIGLFGKTVPKTVKNFVELSTRHSTEVRKYLLNKSDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9I7</accession>
    <name>A0AAV4N9I7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_314821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020598">
        <property type="protein sequence ID" value="GIX80495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9I7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043898810" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="10095" checksum="0CB6F6B971982647" modified="2024-11-27" version="1">MVRFEVFYICFLALFSPFKIPRVSSATGGWEPSPENAAPVKIAVWHWRDPSARRTLENLQRGRFSSKLQCFNQKIVNKKFLATNYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NB31</accession>
    <name>A0AAV4NB31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Partitioning defective 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PARD3_1</name>
        <name evidence="5" type="ORF">CEXT_523981</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003198">
        <property type="protein sequence ID" value="GIX82044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NB31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043296">
        <property type="term" value="C:apical junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051660">
        <property type="term" value="P:establishment of centrosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045197">
        <property type="term" value="P:establishment or maintenance of epithelial cell apical/basal polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052213">
        <property type="entry name" value="PAR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021922">
        <property type="entry name" value="Par3/HAL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16484:SF17">
        <property type="entry name" value="BAZOOKA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16484">
        <property type="entry name" value="PARTITIONING DEFECTIVE 3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12053">
        <property type="entry name" value="Par3_HAL_N_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Par3/HAL N-terminal" evidence="4">
        <location>
            <begin position="3"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX82044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="27123" checksum="5401A92DCB5345E4" modified="2024-11-27" version="1">MHSPSSVVTIHNLKSSRDDGILYPEDQLNDVADDREQIIAVFEESSSPLPPYTYGDVTSMSSVYTGSPDLYSVEVGSHGSNMETEDNPPLGVTPLQVRRGSEPALNCLFPVSSTDPSKRWSTAVVINTDASQDNNSIHENGIEDRVSPVESLDINGDSKMSSLTTFSRGSGRLSILGNSVETYRWVEAADRQLMKACDFNENFNLKSPSLDAGSDTSSMSDEREKTIILKNESGPLGIHVVPDYDSKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKW8</accession>
    <name>A0AAV4NKW8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lhx9</name>
        <name evidence="11" type="ORF">CEXT_717611</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021060">
        <property type="protein sequence ID" value="GIX85411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09377">
        <property type="entry name" value="LIM2_Lhx2_Lhx9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000136">
        <property type="entry name" value="LIM domain family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF168">
        <property type="entry name" value="PROTEIN APTEROUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 9" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="10">
        <location>
            <begin position="55"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX85411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14997" checksum="5E24D7ABCEC5AD39" modified="2024-11-27" version="1">MHERVPVFLFGKTRCELLRGWKLSRGGCSQELGGGGEGVAQDGYIEILQKLFAVKRCARCQRGIFANELVMRARDLVYHLHCFTCAWCNTALTQGDYFGLRDNLVYCRGHYELMVHGESFLPNGTEGPALLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NV06</accession>
    <name>A0AAV4NV06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_23941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021354">
        <property type="protein sequence ID" value="GIX88712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NV06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9251" checksum="02940D43B9495809" modified="2024-11-27" version="1">MAKVKGDSYDRQLRDLFGRWRSRLKEADSQNKQDLPDVMNELFLGAMFLGGKKLILDNNPQNQRNGISYTSMQGDCNVKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1J2</accession>
    <name>A0AAV4P1J2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ALP1</name>
        <name evidence="9" type="ORF">CEXT_195821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HARBI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003943">
        <property type="protein sequence ID" value="GIX90499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1J2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045249">
        <property type="entry name" value="HARBI1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930:SF85">
        <property type="entry name" value="GH03217P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="8">
        <location>
            <begin position="107"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX90499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="36158" checksum="8D2C9BCCF86E0D22" modified="2024-11-27" version="1">MGKDNFMLLVDKITPYFKLHSITNLSIEKQTAITLISMASGKNNACIGRLFLISKSEVAVSIENICEAIKCLMPQYLKVPGILDIKNSTTNFENKWGFPQCVGVIGSIHVPLQKSNLPENASDYINNNGEYSMLLQGVVDSSYKFFDVNIGWPGGAPESRVFTNSAFWQKGQDRDLFPDINEEICGVKIPIYILAGTSYPLSHWVLGPFLDESSSEKEKLFNENFTFAYNTIEIAFKRLKARWNCLIHGNICNIEILPSVIVACCVLHNMCELNNEMMLNDWILTSENFFKQPIPLPCSTVIGPQAENIRSAVSEYFVNSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6S5</accession>
    <name>A0AAV4P6S5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_285291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021717">
        <property type="protein sequence ID" value="GIX92761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6S5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12100" checksum="041C896283040F3D" modified="2024-11-27" version="1">MKSHKKRSGQRGKKRKEFHFGLHDCIEVESKETTMGTADRKFTTRSGNGREAIGNGFWERVISVPFFSVSFRNPGTLSARHFSDVFMHRNGSCSFLSPSCWRLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9S1</accession>
    <name>A0AAV4P9S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_469491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004315">
        <property type="protein sequence ID" value="GIX93955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9099" checksum="CBBB86D4DE3B4DF8" modified="2024-11-27" version="1">MDHHFFAQTQTNGVRHKGAFTRMTGSNKSESKQKDGPREGKKVDGNSFLCEVEFNLIIVRGQSSSNWMYILEMEWVRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PF35</accession>
    <name>A0AAV4PF35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_294741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004392">
        <property type="protein sequence ID" value="GIX94550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PF35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8736" checksum="A825C15ABBBFF118" modified="2024-11-27" version="1">MLIISAFFPEKKKEEKKNTEFVPLKRKQTTKWMEGGSNSKRKTARGVLHSPSKERFSSGLWAVWWGRNGYEGSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PFH9</accession>
    <name>A0AAV4PFH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein kinase C-binding protein NELL1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Nell1</name>
        <name evidence="11" type="ORF">CEXT_670512</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004568">
        <property type="protein sequence ID" value="GIX95851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PFH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008201">
        <property type="term" value="F:heparin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000005">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.200.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051586">
        <property type="entry name" value="PKC-binding_NELL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048287">
        <property type="entry name" value="TSPN-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24042:SF5">
        <property type="entry name" value="EGF-LIKE CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24042">
        <property type="entry name" value="NEL HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00093">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00210">
        <property type="entry name" value="TSPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00214">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57603">
        <property type="entry name" value="FnI-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01208">
        <property type="entry name" value="VWFC_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50184">
        <property type="entry name" value="VWFC_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VWFC" evidence="10">
        <location>
            <begin position="260"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="10">
        <location>
            <begin position="317"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="411"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="457"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="498"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="530"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="10">
        <location>
            <begin position="612"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="10">
        <location>
            <begin position="668"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="822"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="831"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="518"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX95851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="909" mass="101537" checksum="8F8AECD385935B27" modified="2024-11-27" version="1">MCNIKEVSGFHIDSKHQFDLIDGLRIFNRSYTGLTVVEGVNHSPAVLLQGDSRQLQLPAEMLEMISKHLTQTNEFSFMATLKQEGKNTGTIISFSEGNDRFLELQSSGRKDEIRLHYTNKNSTFVETFPYHLTDKNWHEVAISITGNTVNLYVDCNRIYNRIINGIDYNFTGRNISLWLGQRNAHHFMFKGYLQDVKIATQAHGYILQCPNLDTDCPTCGQFQKLQESVQKLEHHIKHLTERLATAESQITTLQQCECAKSCIVDGSTHPDGSTWKHGCDICSCVHGEVKCLPVSCSLVQCKNPVHVPGECCPVCLKKCLFENVLYDHGEKTSPIKCATCECINGSMHCRRIDPETSCPKLECPKEEQFSTPDECCNFCPGVDYCGKGHDCHFNASCMNLNTHYKCQCNKDINECEREGGHDGHHCRDNTNCVNLPGDYVCECLPGYKRADKYNCVEIDECSTGEHNCHENALCINTAGSYECKCIDGYDGDGNECKPVCSVPCLNGGQCVAPNTCSCLHGYTGVNCETDVDECALGLHVCHPNSLCINMPGWYYCQCRPGYESHPEDNLRAFCQDIDECLTGIHTCDLSALCVNDEGGYHCECLENSSCSLNCLYFGEERLSGETWASESCTKCRCTNGVVSCQPVECDCTKRNVNFDCCPHCDHSSVCQHQDASKSFHNGDQWIYQCQTCECLHGEIDCWDLECPPVSCENPVQKPNDCCLRCDDDPCSLPYNTTHSQHKGCAYNGIFYKPGEKVPLIQDPCSSCHCQVPFCQHSDGFICCRYSSNCDDNNNLLDTELLLRNQGTASNVILSPDSIFKDSEMDQDKTTNHSNNSINISSKSNTMGRRLSTFKDFTNTDNEQKRVKRNGYTLNEKEIPIFGNKKLTTALKGAFVKGASIPSSSSDEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGI8</accession>
    <name>A0AAV4PGI8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_93879_1</name>
        <name evidence="8" type="ORF">CEXT_426781</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004619">
        <property type="protein sequence ID" value="GIX96219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03127">
        <property type="entry name" value="tetraspanin_LEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000301">
        <property type="entry name" value="Tetraspanin_animals"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF519">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002419">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="133"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002419-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX96219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="235" mass="26393" checksum="D6893DB8723253B9" modified="2024-11-27" version="1">MTRANSFARHSVCFLSFITWLLGGIVLGTMMWVLATTPSVKNFFTGALVFTYVVLSVGSLLFINGILGWIGSYKRGTCLMKFYLVLSVFTISAEVGGIVALNVLRMKMTDVLSTAWGEVNQMTKNVVQEHFDCCGFLGPQEFVDTTDLIDDSCYYTVKSDDESIVQTKTLNRIGCKEKLVDWFYSNKIIWIASLGGLLLLQVTVVLFAVYVINQIKRARRSNTSSFNDVHYHTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PM14</accession>
    <name>A0AAV4PM14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor XE1.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_64401</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004844">
        <property type="protein sequence ID" value="GIX97990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PM14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051098">
        <property type="entry name" value="NeuroDiff_E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11793">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11793:SF13">
        <property type="entry name" value="PROTEIN DAUGHTERLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="47"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX97990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18942" checksum="001C69EFA09E6E1C" modified="2024-11-27" version="1">MGIYRLVFKCQGHFPGRTELTKRAKGGRSIGEDDDEPPEMKAEKEKERRHANNARERIRVRDINDAFKELGRMCMMHLQTERAMTKLTILSQAVEVITKLENQNENLNPKVACLKRREDEKNEEMKVPLSNPGMSHLIDSYPQMMQHPSSQSMNQHNNLPVSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PMC4</accession>
    <name>A0AAV4PMC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_615121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004926">
        <property type="protein sequence ID" value="GIX98542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PMC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="12926" checksum="75635B42154747F1" modified="2024-11-27" version="1">MNASSPKSLVKSKAAPYSHILIPISSPNESEISKKAIMPALKATEKLTRGVCEWPIFCHLNEIPSLFHLYPPPFQKGTGVRGGEGGGIKRTATAHAFLQKNANEGTTLEYLGGKRLLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPN9</accession>
    <name>A0AAV4PPN9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_657211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004816">
        <property type="protein sequence ID" value="GIX97751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043640974" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9733" checksum="105CA736890F9A67" modified="2024-11-27" version="1">MCCISFLVNWVLLHSSSRLLCVWADSTVGLAGHPPWNAQLSNPRAVPNTPLGRTDRSETLLQRERNKFLLPTHSSCGAHQVIPERPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQ99</accession>
    <name>A0AAV4PQ99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_769181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004858">
        <property type="protein sequence ID" value="GIX98090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQ99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="19207" checksum="F81E2E2D6763B085" modified="2024-11-27" version="1">MIPAEFRYSKIQKSYQQNSRYSRIQKSYQQNSRYSEFMPAEFRYSRIQKSYQQNSRYSKIRNHTSRIPDIPKSRNHTSRIPDIPESRSLTSRIPDISESRNHTSRIPAIPESRNHASRIPDIPESRNHTSRIPDIPESRNHTSRIPDIPEPRNHTSRIPEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQR2</accession>
    <name>A0AAV4PQR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane emp24 domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TMED2</name>
        <name evidence="12" type="ORF">CEXT_587701</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005033">
        <property type="protein sequence ID" value="GIX99343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX99343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="17934" checksum="9728E8D704478167" modified="2024-11-27" version="1">MGLTFEVAEGGFLDIDVKITGPDGKIIYQGERESNGKYTFAAHADGVYTYCFSNAMSTMTPKIVMFSMDVGEAPKGHDAEAEAHQNKLEEMIKELSTSLTSVKHEQEYMAVRDRIHRGINESTNSRVVMWAFFEAVVLVTMTGGQVYYLKRFFEVRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZT2</accession>
    <name>A0AAV4PZT2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_284321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005554">
        <property type="protein sequence ID" value="GIY03188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7377" checksum="A33A7ECF5BF73957" modified="2024-11-27" version="1">MVPVGRFPNGMTMERLRLLSLFYEGESGVIHTSVHSGPKSRGSRGKSSYTASRQHRKSFPPGRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3R0</accession>
    <name>A0AAV4Q3R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_477641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005499">
        <property type="protein sequence ID" value="GIY02771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7901" checksum="28F42DD81B3FE6D9" modified="2024-11-27" version="1" fragment="single">MLKDVEEVDSIHVGRRHQVMRAKTLDNRHLQSYFDYNELINTALSLRFEFSRLFDGSLQFDLGEGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIH2</accession>
    <name>A0AAV4QIH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HNAJ_LOCUS10597</name>
        <name evidence="2" type="ORF">CEXT_54471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006385">
        <property type="protein sequence ID" value="GIY09478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33332">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16887" checksum="1F654A1E69EC3B2E" modified="2024-11-27" version="1">MSKTMERMVYNRLNCYLESHSLLALLLCLLSFSHSLLCSQAGFRKFKSTSHHVTLFSQAIKDAFDSNKDISGHLLNWIKSFMSQRLCRVRYGDGLSKFGLLQTGLPQEAVLSCILFNADINDLVQKLKSIHGVKCLLYADDLLIWTVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQZ0</accession>
    <name>A0AAV4QQZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_271767_1</name>
        <name evidence="2" type="ORF">CEXT_724701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006680">
        <property type="protein sequence ID" value="GIY11677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="218" mass="25726" checksum="FF53E13884225CE0" modified="2024-11-27" version="1">MEKRDSSAFPYTGFYQEIEFHEELLVAPTDVHIEPARTADVTMLYNFIVPSVSDFILVSFTEMVNMLRFYALLKSSTEELEKDLKEPSATKNQDLFKVKRELIDTMKSKFIHIIDLDLLQDTMENPHYYIKKAQFTIELDNMRQDLKKLKEDEALALRDLDQLRFEDTKICYELLELRREFKFLNDSYSTRCEVLPKIGEVREPDEELQDGDKSEDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWK6</accession>
    <name>A0AAV4QWK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_332541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006904">
        <property type="protein sequence ID" value="GIY13199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15588" checksum="73D5AB4766749F21" modified="2024-11-27" version="1">MGTQYKHNPYKSNGPWPYKTQARRRICSQSNDHQRTLNKKLNIPSAKGWCCQKLPTPFPLSRRLFLKLHLPFIRILSGGDGDKRYAPAPTCLPCLSENRSRNCWLDTFLFSFLSFQALFFAIRCVWFSPFRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QY57</accession>
    <name>A0AAV4QY57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_590061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006887">
        <property type="protein sequence ID" value="GIY13052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QY57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17883" checksum="8104127A790C4EE7" modified="2024-11-27" version="1">MANQRPNKKKPAEGYSKFSLPSFRVLNTKFREQKSVFMIHGLMNQQDHLTIMNLKKIIHLLEISKKEKTELEKELKHLEDNAPRKKEILYLLKRMKNQETTKKLLDKQKQERLQKQNEIMEAAKEGKKPYIPKMKSSIHRKDSLWTGLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1Z4</accession>
    <name>A0AAV4R1Z4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_468241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007274">
        <property type="protein sequence ID" value="GIY15735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1Z4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7543" checksum="E254185EE9801CCE" modified="2024-11-27" version="1">MAFNVIKSLTSSADIWIISDSRYHPALRHWMSDGTILFSNSPEGEHRISWGVGDRLLSWISGARESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2Y5</accession>
    <name>A0AAV4R2Y5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_422441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007288">
        <property type="protein sequence ID" value="GIY15832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2Y5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16331" checksum="BABE23EE94700BFF" modified="2024-11-27" version="1">MLLKIHHQHQSIDSNSFQNTAFFDNRLKREDLSETTAIETKSSLNRKVPRLKILNEAKGGAPFFTYEAEANLKNAGETQRNIRTEISSIFSSSVFRLLDDSACRTNDMFRKENILNETIENSSDVKLHNLYIQKDGIFLYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8X2</accession>
    <name>A0AAV4R8X2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_777511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007564">
        <property type="protein sequence ID" value="GIY17920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8X2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11419" checksum="9AF5CF17C3693EA5" modified="2024-11-27" version="1" fragment="single">REQQSFFWAARRMSPESPGLTDKESGSKTPTNVAAGSPIHLHEGARSATIILFGCTKSESRISRTQGQRVREQNANKCSRGSPIRLHEGGMTKTHGREEGDLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RE00</accession>
    <name>A0AAV4RE00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Neuropeptide Y receptor type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NPY2R_1</name>
        <name evidence="1" type="ORF">CEXT_343161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007849">
        <property type="protein sequence ID" value="GIY20188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RE00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9894" checksum="507F5AF684BB690D" modified="2024-11-27" version="1">MRISAKEFMIVLPCFKSKVLAQNPVSRRAISGKADKSCNGHENVTLLPMKEIANKDRNFQKDRVGATKNNTSVTETVRINVTSNDIDAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFW8</accession>
    <name>A0AAV4RFW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_118481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007719">
        <property type="protein sequence ID" value="GIY19115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044011242" evidence="1">
        <location>
            <begin position="24"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12770" checksum="F45DBD08125794B3" modified="2024-11-27" version="1">MYLRTVNVKLLCIIWHLLVVVTSTYDTLDSTNEKPSTSLKNLIISSPQGTIEENDEGEKKPFTCMKSENEPCKKRRWRPNHFTRFRKKLVRSLWSTRGCILGLKNDGTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RI01</accession>
    <name>A0AAV4RI01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_637561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008028">
        <property type="protein sequence ID" value="GIY21538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RI01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="15306" checksum="8B05D78C0E302BB6" modified="2024-11-27" version="1" fragment="single">MIVPHFPNPSDREWKERCRKDQRLHSIQSLIHRANKYTQKKNATPLKYIHGLQRRKIEILRPRWNCTQRLKDLKGDGTERASNNTTQKKKKKVAPDVDVTDCRRKEWRFSRLTEGGIAERRKTCLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNX0</accession>
    <name>A0AAV4RNX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_585301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008097">
        <property type="protein sequence ID" value="GIY22031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22368" checksum="5C1793428B0C4C83" modified="2024-11-27" version="1">MPKSQRTKLKREYPWSHLVESILTRENKFNRRNAKVIFDAVKTRIQINALMKEIQNCKPDSPKNTWMSWKKSSSFGVSTSDLEEPKPLPPKKTAPAANQVEKVIQKGALDIAVSRNAMDKLEKSLSQADPSSENAARIRNQLTFYADSYKVKLKRGKSNEPSPTEEPFQIPPKDSPAETKPRIQASKVLKSKTNSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWF6</accession>
    <name>A0AAV4RWF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_583961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008569">
        <property type="protein sequence ID" value="GIY25702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13944" checksum="597308849170797B" modified="2024-11-27" version="1">MCYLPLGRLDLFRNSTLRRIQQGRACYTNQHAILICNEKPSKVDSWVFKQSFSSSVSEHFLAYNLNAPIANDFWGGLICYLALVPQACWDCLSPIDCWGFEKCKSPLELLDLSLDSIWHPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXM7</accession>
    <name>A0AAV4RXM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_790331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008631">
        <property type="protein sequence ID" value="GIY26137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="20" mass="2454" checksum="DD8AEAF0F30C1E81" modified="2024-11-27" version="1" fragment="single">SNWTFKALFELKIWISVNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXZ6</accession>
    <name>A0AAV4RXZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synergin gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SYNRG</name>
        <name evidence="3" type="ORF">CEXT_705971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008697">
        <property type="protein sequence ID" value="GIY26539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039656">
        <property type="entry name" value="SYNRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059024">
        <property type="entry name" value="SYNRG_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15463">
        <property type="entry name" value="AP1 GAMMA SUBUNIT BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15463:SF2">
        <property type="entry name" value="SYNERGIN GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25999">
        <property type="entry name" value="SYNRG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Synergin gamma C-terminal" evidence="2">
        <location>
            <begin position="264"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY26539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="361" mass="40014" checksum="884CD4FB70CB3941" modified="2024-11-27" version="1">MSPEEDKYSIFRTLQQVENTDDWGDFSSVATDLMSNVDTKLSDTEEFSQKSETISSELQANPSVFVTSNDSNLDLFKMENPAPIDTTKDDDDFGDFLHAEPPLPTVDAVTSQLKDLNTNFANFDNFKEPINSIEFHQMQLTGPSNNSQLDDEFEPICVQFGIGDLDGGGHSGESKSSLSRQGSIPSLDLKNTFVEGGEGEDYFGEFQSPVPPVNTSSKSPSPAKDVKGPENNGLCNNLLNVNFQNVRSVAPLTDKYSVIRAEERKDEDQHISCWVRCLQSSLNILQNTKKIFNQMSCSSVCNEVLRSEEGENYIKGNDQVWHTICGFFAGSALMPKESSLEFSSAILGRQHQSLWLVSFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYQ6</accession>
    <name>A0AAV4RYQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_60571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008763">
        <property type="protein sequence ID" value="GIY27028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9874" checksum="5A33BFE89003E2AC" modified="2024-11-27" version="1">MLETDSFLRAPYFQCLFFSKHEPVAVSLALNLMASKVSENRLTLTITGFSSKKAENALKTKSPLACTRLNSPVSVEEIQQHKLQPYKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S5L7</accession>
    <name>A0AAV4S5L7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_347641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009003">
        <property type="protein sequence ID" value="GIY28930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S5L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="29087" checksum="D97B6F94C542F8FF" modified="2024-11-27" version="1" fragment="single">AQAVGELKTNFAPPFPCLESGKAGRSSVRRSTLSAAALRTAAVLPGGKGSAGMFLPPEIRKRYAGEDGRSRAKQKTKKLNFKILPESPPAPECTCPPSCWLPPFLQTPAQNCVPGSIGFGKNVRKELTKKTIRNGVICKGQATEERSLTWEKEFGSIVIHLLFGSIKPFLIVGSRSRRNHRPYAGQEGIKFHEKTDEGTLKSHLNDNVCSPQAIRHPFLPIWGSRLGGGGGTVLKEVVASFAIVFGNPRGIARVANPYSCVTRSGRRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6P8</accession>
    <name>A0AAV4S6P8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_397931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008994">
        <property type="protein sequence ID" value="GIY28846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6P8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043596036" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="11060" checksum="1A3E06A2C727F6A6" modified="2024-11-27" version="1">MGSTIIFSLIFGHTVALLELPNRHSCHTVNMRPGPWRQSVVWCCRVSARQLFYVTTRQDIFHRVVPGTSNQGIGKPRSINHMKEQKYMLVRIYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SF61</accession>
    <name>A0AAV4SF61_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 11">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Tpi</name>
        <name evidence="12" type="ORF">CEXT_691541</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 11"/>
    <dbReference type="EMBL" id="BPLR01009496">
        <property type="protein sequence ID" value="GIY32350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SF61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY32350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="235" mass="25360" checksum="F3E8307196E86722" modified="2024-11-27" version="1">MNGSKSSIDGIVKFLSAGPLDPKTEIVLGCPAIYMDYAISKMPKTIGIAAQNCYKVASGAFTAEISPAMIKDIGSEWVILGHSERRNVFGENDALIADKTAHALSEGLKVIACVGELLEEREAGKTQEVVFRQTKAIADKVTDWKKVVIAYEPVWAIGTGKQPSPEQAQEVHEQLRKWLAENVSADVAKTTRIIYGGSVTASNCKELAKKPDVDGFLVGGASLKPEFVQIINARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJ24</accession>
    <name>A0AAV4SJ24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_248551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009554">
        <property type="protein sequence ID" value="GIY32831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJ24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043315860" evidence="1">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11963" checksum="E7D5D09F99EFCEA6" modified="2024-11-27" version="1">MTPVFWLLVLGFALRWSAFWGCHLSGTTNRLKNPSDALAELIKTLKTESLLRDVRRGVQEKPVNGERELGEASLKIHEMPVCIYFLNGLKNLMTPVSDHARQLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNU8</accession>
    <name>A0AAV4SNU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_544021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009742">
        <property type="protein sequence ID" value="GIY34227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9321" checksum="FD7922870B5709DF" modified="2024-11-27" version="1">MTKVLKYFLNPSPLANQPIAPSPSTYLREMSQTWIPPHSICLLLTSVVRKSLLRFNDLVPEASQKVHLFVGLPNSELFQGKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUQ6</accession>
    <name>A0AAV4SUQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_604061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010218">
        <property type="protein sequence ID" value="GIY37789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY37789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="21422" checksum="2D5B2EC2CA2F5A8B" modified="2024-11-27" version="1">MNFSELTLNPNGGGRAARLHPEQLPGRGGPPRQVRQHPGDGQGPEGPLRPARGRALRTRGHHHHPSSRPTPLLCTSRTTLVGRPSLRNGHDKSGQNCQSSHHSWSLEDNQRRENALPQLLLHLQRRDPETARGGISARPEQPLLTATASCHVLLTLYLLWNFYILIHCSFCTVSLVLLMPVTMDHNRVVPLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVB4</accession>
    <name>A0AAV4SVB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_660771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010163">
        <property type="protein sequence ID" value="GIY37342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12755" checksum="F0EC194D63B1FAB4" modified="2024-11-27" version="1" fragment="single">TESIHAVFVCTAFDSLRWLDTTANIKAILLSELVLTRIKTLFRDIQSTLMSSVACNQQSIRKNIGQRHKKVVVIKDLPPLIRLKQKEDSSLLDIEPNDNIGLCNLFSDNQNSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4L3</accession>
    <name>A0AAV4T4L3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_159591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010492">
        <property type="protein sequence ID" value="GIY39665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4L3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="24318" checksum="1ADE904D990CD595" modified="2024-11-27" version="1">MLMLLVSPGKPLPAHQDPGRLLTHCVPGLPSPDRATPPTASDGPQHDRSHTGGARGDGGERGHAHRRAHGRRAVRGAGTAQVAVRRLVRRRHPRQPHGVRRSISYATINELYPELEWLRIYTDGSRVEQRIKSDLFSVYALVGRFASACEVEAFTLPLEIKTFQYTHTRSVVTWVRKLKLNSNKCPTALKSWALAAFPARNPRSCGDRWDSKGCVPVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T864</accession>
    <name>A0AAV4T864_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_68061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010827">
        <property type="protein sequence ID" value="GIY42295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T864"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13816" checksum="4E004D313D490B1E" modified="2024-11-27" version="1">MLNNSSQFINSLQFRTRRHPTLNSSLQFFSRPPRFESSHLATSQEAAPIAKSPSKASNLQGRHHHRYPPWYLNYLVTRAGMVAPRLPVSAPNEGRTFSTSYLRPSRQPVCAPRLKGWRNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCE8</accession>
    <name>A0AAV4TCE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_749121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011034">
        <property type="protein sequence ID" value="GIY43795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12623" checksum="CED567BC90E84669" modified="2024-11-27" version="1">MKAALFGFTNLPFNLSDSSESPSSVHVIAQSGDYPGINVAQFPGRIVLCSGGTERPVEREICNRSGPIKGISSSEKASIRSRCKMSFYSRQSGSYWLEREVPDMFTVGEKRVKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TL13</accession>
    <name>A0AAV4TL13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GLTSCR1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_265293_1</name>
        <name evidence="2" type="ORF">CEXT_981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011563">
        <property type="protein sequence ID" value="GIY47303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TL13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="407" mass="42750" checksum="391D37B204CEE7F4" modified="2024-11-27" version="1">MDDGGRCLLDVINDPKLLQSFLESGSDENSKDFPDGTSSESAIESPQVPRNSQAAHASNISSADNLIDQTEMGGTSFILTPTSVGSQTYQHASSSGATIHHHPSTTNNVNFHPHSPASARSVTPSHNIKSPNVGPSSVNSMPPPSPLQQTKSPMPSHTPSPVPSWSPVAPVSPAASRNQPSMPSVAFQQTQNQILQTSCNPTQYVTAFTTPQSVAQKLTVQQQQQQIYLQQQIPPASQQQTTPRLTTVPTPCSYNCSCWGSTTSKTTPQILPKPATSSASNQYVSPASTPKQTQTIPATTGQRTLGIQSGAAPLVINQAQPGMPSSNPSGQTLNSSTTQNNALIAALQNPNQQAIFASAKQSIHGQQTIMIPNNIAHTGLAPQNINLTSAAIPNSGIISSSSQGQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMD3</accession>
    <name>A0AAV4TMD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_727661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011611">
        <property type="protein sequence ID" value="GIY47723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14928" checksum="290C88752D1543BB" modified="2024-11-27" version="1">MTANKTRRASFFMYDITTPSMLECKYSCSIFFIFIVCDENSSPNLGEEFAASLQKLIGTRVIFHSFILSCQKFHVVGNAGDVLLRVGQSGVQLSLGYLPCNLWCETLCATSSASEHSSSLSATLERIRKLLWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TTA1</accession>
    <name>A0AAV4TTA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_53991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011739">
        <property type="protein sequence ID" value="GIY48656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TTA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19158" checksum="8FC69F14FC439E66" modified="2024-11-27" version="1">MNNSSTRPTKSHLNKRNKPNYPNSSVPSSTAIDPFVRARIKSQEVGCTRFFFFFFFFQPETFLCTLKYLFSNVSCRCCYRRGKQIIGEKERIIPLADSPFLLHPPPTLPFSPDRSHVNPSAARETKESSSREKVNKCYAQKEFFKCFAVEKHLNGERDFGFNFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3B5</accession>
    <name>A0AAV4U3B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_36621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012220">
        <property type="protein sequence ID" value="GIY52289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7046" checksum="1CA02736F02212CA" modified="2024-11-27" version="1">MMKSRDTIDMVDMVRYGGYGGYGSGYGGYGSGYGGYGSGYGGYGSGYNRYGGNRYGGYGYGYNSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3D2</accession>
    <name>A0AAV4U3D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_174891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012206">
        <property type="protein sequence ID" value="GIY52182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10165" checksum="EC82AE6015B444F7" modified="2024-11-27" version="1">MCAATAKSILNCKPPAPTTQRELKARLEKGEIRVMHHLPPLPIALVTRRVYKETSRLREAYAHHSNCNNLSGTTRDIFHQLTVFGQGICR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UP07</accession>
    <name>A0AAV4UP07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_487781</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013213">
        <property type="protein sequence ID" value="GIY59533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UP07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY59533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="19128" checksum="E410F8BDB3E44161" modified="2024-11-27" version="1">MSAVNVKGLTFSREFVSEVFAILFPMQSEFNPSAAANASKLSNKMKNGILTLVYRHLIELYFLFTFEEFAFCKPLNDETFREMLEEMKKDFKEDFDCAEFLYFCLVVSVYCVMAFERNCPNAKKHAARAIYDTLKYFEDIGQFTDETWVELETCLQSIIAKLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQ09</accession>
    <name>A0AAV4UQ09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_435901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013243">
        <property type="protein sequence ID" value="GIY59795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQ09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY59795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10983" checksum="1A9859FDADABAE85" modified="2024-11-27" version="1">MSTSEIQVSTGARNPSPMEMSVSPTMMSAGLSKPKSPNEPLTVHSSSNLEINPPAPAPSSIPQEPAPAEYISFAEDYFLDRTMKLYQRKLKRNLSFPSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYS2</accession>
    <name>A0AAV4UYS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_123681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013668">
        <property type="protein sequence ID" value="GIY62804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="21" mass="2048" checksum="27ED40DCA7E6FAE9" modified="2024-11-27" version="1" fragment="single">MVSGHAVGGWFGGLKESGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V169</accession>
    <name>A0AAV4V169_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">A disintegrin and metalloproteinase with thrombospondin motifs 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADAMTS1</name>
        <name evidence="11" type="ORF">CEXT_418421</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013813">
        <property type="protein sequence ID" value="GIY63982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V169"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF249">
        <property type="entry name" value="SOL NARAE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13574">
        <property type="entry name" value="Reprolysin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="10">
        <location>
            <begin position="17"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY63982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="250" mass="27515" checksum="B522FBEE6B7BBC0D" modified="2024-11-27" version="1">MTKLDMCKRQYTRGRCSRGTAGFAYVGGACVVNKRLEKVNSVAIIEDSGGFSGVIVAAHEVGHLLGCVHDGSPPPSYLGGPGASRCPWDDGYIMSDLRHTDRGFQWSRCSLEQFRHFLSGETASCLFNYPDDNKLLERELPGTMLTLDEQCERDRGTQACFKDSRVCAQLFCYDNDSGYCVSYRPAADGSFCGDGQVCKNGKCMVNNINIIPDYTHVTRSIANLNDNKEVSKQTTSRPSISRVSKTSMAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4Q4</accession>
    <name>A0AAV4V4Q4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_65351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013892">
        <property type="protein sequence ID" value="GIY64530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14276" checksum="62C7D734D1C228C8" modified="2024-11-27" version="1">MYLKVTDEPFKDLVMMSSIFVRLTMDEGLPSQPTDVVSLQFGTNVFIGLVKQIPFKETAPSCALNNSFVSACFMKPGTINSLMTKRLATNRPVPAAPTGKEIWPFLMLLGSDFVRIFPFLADSEDSAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5Y6</accession>
    <name>A0AAV4V5Y6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_807791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014014">
        <property type="protein sequence ID" value="GIY65650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5Y6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="18529" checksum="C96D9A6A5AEBD7D6" modified="2024-11-27" version="1">MARGGGEIDFVPSTALSSTLPLRQQVTCSHPEGYRWSALRDVPHALKKKKKTAQAGDLRSFTANGQQIFNFNQEAPWRETATLDTYFSAIVSYGHPGGATLANDPIYAASCFVPESYNQVRPDGQLSNSGLWYHGLQASPGSRAPVLNVTLGKKEGKISSLFPDNGGKAMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDI1</accession>
    <name>A0AAV4VDI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_358011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014339">
        <property type="protein sequence ID" value="GIY68201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8831" checksum="42DEFFB7BEDB98B8" modified="2024-11-27" version="1" fragment="single">IRVQGALRGLSSIGHLENGIMEDCSSIGYLEDVPGKWHYGESHSIGHLEDGIMKIVFCWTPEDGIMEDCLLLVTWKMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDM8</accession>
    <name>A0AAV4VDM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_55834_1</name>
        <name evidence="1" type="ORF">CEXT_88791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014338">
        <property type="protein sequence ID" value="GIY68198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="342" mass="40022" checksum="052F05C24A49EB61" modified="2024-11-27" version="1">MNQQDKNLFKSFTSFNLLPVCCISQKKICFTVPEKISRANVTTTINNRFITEFLNYVKTEDVLQALKELQNMKKGYIRSLTFNDMTLFLDLLIRKKCLADLSSNVQAMSYVIQFVNEVFKPLLEKYSCSGDIDSIYEIATLLPDFALSKCNFNHYLTTAYIKSGKCEDLLYELEKHFNHVRIKLFTIPAFLEFLKRPDLEERTIKLANKYLEVNFDLPIAVVWAYYLTHENYEKANEFYLLYKIPVEKVATMVLKAIREQENVTMGKMYISILDDNSKNRLKERAYATVLEILISKEMYNDAIALITEAREKNIDVEKQYRSILVRLKIALEKEKKEVPFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGM6</accession>
    <name>A0AAV4VGM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_794021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014512">
        <property type="protein sequence ID" value="GIY69281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14465" checksum="6D9679FF43CFAAD6" modified="2024-11-27" version="1">MRAFPAASTLPSTSTSILKVYSRPLNFTCRPRMSVYVPKNSQLRTPDQSGRPLISSAQQKVADLSLFTNATGCTAHSFLFPFLPKHRQKKHMYKGTLKFLNFLIIPFELPSYSIFIDLERWLSLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VIM3</accession>
    <name>A0AAV4VIM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_709621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014592">
        <property type="protein sequence ID" value="GIY69815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VIM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="13124" checksum="A712695DD118B144" modified="2024-11-27" version="1">MNSNTEYGAKNRSFLFFKARNNVLAIFFRNLLFILIAFHHFTYQGTNDKSLNIPQTQRTRIPMCTYTTDFSLCRNESNEMEETLRKYFAMRKLFPGDKKRRRKIPLRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMN7</accession>
    <name>A0AAV4VMN7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein P1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60S acidic ribosomal protein P1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_791221</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the elongation step of protein synthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014761">
        <property type="protein sequence ID" value="GIY71180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05831">
        <property type="entry name" value="Ribosomal_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="66"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY71180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="11557" checksum="3ABFE808F9EE2A2E" modified="2024-11-27" version="1">MISTDETACIYAALILQDDDIAITAEKISTILKAAGVNVEPYWPTLFTKALVDVNMKQMITNVGTGAGGAASASAGVTTAGGEASATAEESNEEKEESDAESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTZ8</accession>
    <name>A0AAV4VTZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_569891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015122">
        <property type="protein sequence ID" value="GIY73802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632:SF3">
        <property type="entry name" value="KELCH-LIKE PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632">
        <property type="entry name" value="LD33804P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY73802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="426" mass="48112" checksum="74DA44033E67A2D7" modified="2024-11-27" version="1">MYMCGGFDGDEIQSTAEVYDPDMDQWTLIGDMLGPRSGHVLISYQQSLLVIGGYDGETRLRTVECYDEEKKTFVEHVPLNHVRSNFAAAVVEDQLHVIGGYNDKFHITIQRITLSETSMTNSKSQFLLIITIKCYQKQTNLKLLGKKVCDSYNLDFLGPQRKSELEHITKKGTIEATRRPRSIPSPQSHTNFKFDNNYILFASACIPLVVVVMFCLWKSRKNGQKSSNKSNKYNVMDEDNLVDFEHLNKGKENRIKSPKFSVESSISASHLLISQDKSSSSVHGEYYHFTDCNSINPATKPSCHDDCLSHLPSLNLLIYNGYTRDMTPTSTDEETSEDGTLSSKIPDFDDEEHRLKSITDVTRGSPSCCASLNEKEVEMRYKGVMNTADMESSTSTSSDDTFSVPSSDYINQSHIKKMYRILPINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VU65</accession>
    <name>A0AAV4VU65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_11458_1</name>
        <name evidence="2" type="ORF">CEXT_591401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015144">
        <property type="protein sequence ID" value="GIY73957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1193"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1282"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1194"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1453" mass="159527" checksum="0572E100F5C6A998" modified="2024-11-27" version="1">MWKNDFEKKSCCKYGMRMPPKRLQSGEKIHVYQCDSSDPSSKEKKTGVAVKENCPALISAIESAKTHGVKVEIWDSHVGHAISNGEGMNSVMMYKYDSAPFFIAVTPATCICSFGVAEITYPSDQSYHSVGMDENIFILPESSNSSFSESFGSEFSKKKNSRSRDKTKKIKLCEDVSQSFSQKFAYKKDPSKKTGSMCRSLASVACMKASTKKKVETSALSTLTDSVTEVVSTISSCISNTQVTSSVEGVSNEVSVDCSISDFNCKSKTEENQVLPLSPVKVESTENDDMSITPDMIGKQPTFAVIGEGPLSGHVVLLNTVPPSIKDQTTVHSPNQNLIPIGSTISVETVPTKKDKPSNNSEMNNIIPDVVIYPVASENEKILPTKNISGIVQNPNSFKDSKVSSPSILKKIKKVGQNSIKKYGKKNFFVSGKDTSVLGKRKASPEKNIYPVSPKPILPSNIINSIHLVSSTPNMSTSNIKGIIPHSAPLKDTNSVQHNNSTPSNSISNFTSTVPVYSNSKTRDSLPTSKDSAGNQTVLSSFPPGQAFMSINNNLIPIGTLGTPILQSNLNSSFVLTSTVPTSPIIRPIQTAANFTPLTSRLPVTSANASLQTLNSKVLDNEKLPAALPASGYKDDTGISNIVLIPQTKIGSSVSFSSPLMSYSIRTTTSNSVGPNRIQPVISNPLVSGGINSVIPRPLISSGVGPVFTRIAPGTQIISTPLLPTNTQFIPSPLLTNQRNSRPILQTKGSSLPSSLIGQPSIAIVTSTNVFPKSIISTTVSNAVKVQKVNLPVTKNVKNPSVPVSKKNKTTIVSEHMKVSNVVINTQPIISTPAINIPQLSSIAPQKHGAFIFESSGDVYMLEPMEENVQSKKEYDQNVEKTSMSVRNSNEEISSDLINNSDKIVEPAHSDVSKEDVLFNTTESACSDTSKEDYFSKAIESSSSVSSKEGGFCSIAESTPSDTNKDNELCKSTPLDKSKEHCLSNLHLEKGDVVENQNNLDVKTEGKLKSLSPSKMFVSSPLDPNNSVQIKSITQDKRPLTDDDDIEILKKVKYYQMEMKYLNSLADCKQLKLELAKAQMKNREMEERRFTDRILNNQLEKGTSNTDVFVQLTENLESKCDTNINELAGNLVIDIDSLNDQDSNIRMNINKCIETDQLSHSANQENNNINLNNNCKHANNLDKKQLDNQISNDLESKTDDNENKKGDFEDKNMDCNDLDNQTKTKEGFEEHSLDISDEQSYDCNLSDQINSIDSVEEKSVNTNESDSVRISKCIENNTKTDQSILDTEPTKQFSDKENDPVFLDSNTTDNEINFRNSKFFKENSINSNAVEKSSNTNCELSALQNLDEGKELKCINNEIADSIKSKDKEIQDAITCEVFHHDAIKELESRYKTDECLDIFTMIRTSVLRGLHDEVKTLYDENEKLHKMLKNADLGRTAPIETNFLEEFVQVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZ84</accession>
    <name>A0AAV4VZ84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_423301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015344">
        <property type="protein sequence ID" value="GIY75458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZ84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY75458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="10526" checksum="0659D01396D10586" modified="2024-11-27" version="1">MGGGGVGLLIALFGIELFMWSVAIGVWVTTSTIEHNRTPPPPPPNPKVIDDGTWSEGENVTGHRSRWMAAFGSCNDGGRGGVGFGRAGACGDLDKISCHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W156</accession>
    <name>A0AAV4W156_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_699831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015487">
        <property type="protein sequence ID" value="GIY76446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W156"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13837" checksum="DE7691BA1BA4B747" modified="2024-11-27" version="1">MYHPIFCQPTKKWQNLKANNVTSLAHSNALLILLIIASRVNSPARLKRPKEIVTRATLPVKSDLDIMSLKGKIQQRFDLVIGRAPSYFRQVSTAPNPHFTPQVGPYFVWEKQAHYLRCLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W492</accession>
    <name>A0AAV4W492_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_263651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015612">
        <property type="protein sequence ID" value="GIY77366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W492"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12154" checksum="7D5778FB8B594524" modified="2024-11-27" version="1">MKKRTKAIGFSFQEFIGFLLFRKRDASDILYEISDGSTLFPGFLLFRKRDASDILYVRDQRWRHAVARYGISTQFDFLKSALLYWYLFSTLSVAPDSLFRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4Y4</accession>
    <name>A0AAV4W4Y4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ATM</name>
        <name evidence="11" type="ORF">CEXT_751361</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01015580">
        <property type="protein sequence ID" value="GIY77135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4Y4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="10">
        <location>
            <begin position="281"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY77135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="35459" checksum="2446B2615366BED1" modified="2024-11-27" version="1">MCGGITLPKVIKCIGMDGKEREQLVKGSDDLRQDAVMQQVFYLVNYLLKQKMETRQRKLHIRTYKVVPVSRRSGVLQWCEGTEVLSHYLVGPGGAHRRYYPSFATPQEYFFLENFPEPSAWFERRQSYIKSVAASSIVGYIMGLGDRHVNNILIDKNTAEVVHIDFGIAFEKGKILATPETVPFRLTRDIVDGMGINGVEGTFKRCSEKTLEVMRNSQDVLLTILEVLLHDPLYEWSVPAGKSSQRADTSSTSNSQKEINTLAERALMRLQQKLQGLEEGVAMSIEGQVNLLIQQARDPNNLCRIFAGWQPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBI7</accession>
    <name>A0AAV4WBI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RPA-related protein RADX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RADX</name>
        <name evidence="1" type="ORF">CEXT_44111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015938">
        <property type="protein sequence ID" value="GIY79856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040893">
        <property type="entry name" value="RADX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14944">
        <property type="entry name" value="RPA-RELATED PROTEIN RADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14944:SF2">
        <property type="entry name" value="RPA-RELATED PROTEIN RADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17659">
        <property type="entry name" value="RADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="396" mass="45518" checksum="0F16935905F66CA9" modified="2024-11-27" version="1">MAGNLKQFRSILREYKLISDSSRIPGEFQIKVGSYVQIQKAKLCYLEGEYNDSHIVQYVLLEAIKILEYLVVTFPNLEELQFVESTNYRETQSIPLVTSRKCYTYPWLPVYPYGEEWTTNGPLELSDTDDVPQNIFILQNVADDWTRMPKPYPTIFVRVLARGMLYYYGFNKNDKSHPFMAKLVVGDSSSASMCVLFGKGAMSLYYHALPGTILLIEGYSIYKLQNPLYPRLQFSFANRAALELAANESTVDVIGLITHVSLFHRFMYKFGKYHARCYLELIDSSSHLPFVVIIYNNVLRFPVEDIHPGQVLVGTHFKVHHLQDEILSSYQVRTYLKSTHYTELFTTHGQNSLYVRYPAVTAVASIIRDHQQEVDFLQANVLRAGGIPTFLEAINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJA1</accession>
    <name>A0AAV4WJA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_543751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016183">
        <property type="protein sequence ID" value="GIY81944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12437" checksum="29485DFDF5B41C21" modified="2024-11-27" version="1">MEGGSCGREEGVQEKERFENVLSLLFFCNLQSQGIPSQKIEAMCITASVIGNSGTPRQCDAFFVSGLYLCNCRTEHDVDVHLFYIRLCNQAISTTVSHSLSKEPSLGWEGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WNK9</accession>
    <name>A0AAV4WNK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_801001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016440">
        <property type="protein sequence ID" value="GIY83903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WNK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9906" checksum="1DB098D4E8A550E4" modified="2024-11-27" version="1">MKCMNNLSSKQTAFPGWGDKFLVFGRTVEDHFLSERASHSLPVRFPPLRAESFILNDFIHNIRRRRAVLIIGRSAPLESTVVCEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSQ6</accession>
    <name>A0AAV4WSQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-fructose oxidoreductase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GFOD2</name>
        <name evidence="2" type="ORF">CEXT_734101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016545">
        <property type="protein sequence ID" value="GIY84694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050463">
        <property type="entry name" value="Gfo/Idh/MocA_oxidrdct_glycsds"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43818">
        <property type="entry name" value="BCDNA.GH03377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43818:SF11">
        <property type="entry name" value="BCDNA.GH03377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="22764" checksum="F2A424F0E32D6DDC" modified="2024-11-27" version="1">MQKVVRDGYIKICLSVMQVQCEVYHDRYDWTCDELMGGGLLTNVGSHIIDIITYTTGRRACVSMVCEGHVVVRGGDLYGQKTTALKEEVLYLDIEDLKQSSVISHSSSPSSVDMTQNNVNALLPKPYMKGLLKMIGALKDAFATQEDLQSWVKEPVAMAATFEDGQYIQTVIDAIRLSSKAREWVKVELLTEDPDTQQHLSSMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUQ1</accession>
    <name>A0AAV4WUQ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_377981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016800">
        <property type="protein sequence ID" value="GIY86472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10557" checksum="9F997EAAB0C924B7" modified="2024-11-27" version="1">MMILMWCCVTPSDDFDVVYRYIRTAELICPQAPRIACATVKGKGARYKGGRRHLVRLERCAKGGWMESLVRFAAAVKWIRVQGWCSCQPIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVV3</accession>
    <name>A0AAV4WVV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_651961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016672">
        <property type="protein sequence ID" value="GIY85653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9265" checksum="6705F46997D150A4" modified="2024-11-27" version="1">MFVRPCVRKAKMSKNVPRGEGGKKTRRCLKRARKHEALESDSGRDHRRRDHEDQEPRKTERIKEIGGLKSRRLARFHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXD9</accession>
    <name>A0AAV4WXD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-L-iduronidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IDUA</name>
        <name evidence="7" type="ORF">CEXT_212511</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016779">
        <property type="protein sequence ID" value="GIY86314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003940">
        <property type="term" value="F:L-iduronidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049165">
        <property type="entry name" value="GH39_as"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049167">
        <property type="entry name" value="GH39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049166">
        <property type="entry name" value="GH39_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000514">
        <property type="entry name" value="Glyco_hydro_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051923">
        <property type="entry name" value="Glycosyl_Hydrolase_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12631">
        <property type="entry name" value="ALPHA-L-IDURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12631:SF8">
        <property type="entry name" value="ALPHA-L-IDURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01229">
        <property type="entry name" value="Glyco_hydro_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21200">
        <property type="entry name" value="Glyco_hydro_39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00745">
        <property type="entry name" value="GLHYDRLASE39"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01027">
        <property type="entry name" value="GLYCOSYL_HYDROL_F39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolases family 39 N-terminal catalytic" evidence="5">
        <location>
            <begin position="2"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-iduronidase C-terminal" evidence="6">
        <location>
            <begin position="310"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600514-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY86314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="401" mass="47128" checksum="2183B83B75C3B5A3" modified="2024-11-27" version="1">MFGIDYVMKWNFETWNEPDHHDFDELNITLQGFLNYYDACSEGLYSADKRLRFGGPGGSCVRLDFISFHKKGNASTNLILDEEIETIEYIVSNFPSLINTSIFNDEADPLKNWSFSQWWRADSTYAAMVVKIILDHIYFYYFTERTLLARFQVNNTSPNYVEFVRKPVYAAFGLLNKLCPNVLSVNLTSGDQPLKNWGQEFGAIATHCVSGDVVILFVQYRRHFSKWNSCSGRCEFEIPKRKKNRAVRWAILEINNVKSNPYLVWENLGMPSYPSIEEFSLMKRKRGAMDERTMGLYKNSHNLEFHLNVTNVRFFQTWNKTVEISWTDKHNSCVLTYNLLHNSHLHGPYNQVNKKIFKFPSYWHTCYKKKNNCDIKGFYKIYPVDYWGRRGPDSDIFHFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1R9</accession>
    <name>A0AAV4X1R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Speract receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_673771</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017025">
        <property type="protein sequence ID" value="GIY88130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000115">
        <property type="entry name" value="Soluble guanylate cyclase gcy-35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF501">
        <property type="entry name" value="GUANYLATE CYCLASE 32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="4"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY88130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="283" mass="31696" checksum="E2806D30BC753AFA" modified="2024-11-27" version="1">MLRASTLSPSISVTSWDSLPSRPSALLYRWLIFLNDLYTCFDSIIGNYDVYKVETIGDAYMVVSGLPIRNGDRHAGEIASLALRLRQAIETFEIRHRPNERLSLRIGINSGPCVAGVVGLKMPRYCLFGDTVNTASRMESTGEAMKIHVSEACKKVLDKLGGYRLEERGLIQIKGKGEMRTFWLLGKDVYDPLFPPKISPSPSHQSKIFNEKQFSEFPSDNSVEVSSFTTSLNTNDSCASLFQECKKNAKNDSFRANGYRSAPAIINKLQLSYIHQQTSYCDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4M8</accession>
    <name>A0AAV4X4M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_695051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017217">
        <property type="protein sequence ID" value="GIY89507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8728" checksum="0611262C283884DB" modified="2024-11-27" version="1">MASEILQINYLDLNRPVLTGDEVNSASLRSDKSIIWTCTCMFLPQMRASEILQINYLAPDRPVLTGDEVNLASLKSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5E8</accession>
    <name>A0AAV4X5E8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_181711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017202">
        <property type="protein sequence ID" value="GIY89405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5E8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8992" checksum="643F5FBFE3D5D077" modified="2024-11-27" version="1">MVVHISEKSHKCSGQRSTLKRHLRTRTKECCVKELKQLIRLSPVFPVSPKRCFVDGLHSASESQLPIESEQLLSCWCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X772</accession>
    <name>A0AAV4X772_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_154821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017265">
        <property type="protein sequence ID" value="GIY89821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X772"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11169" checksum="F77C697E39D40D5C" modified="2024-11-27" version="1">MTIHFVHEFKERFILARVSVLSYGTKCAQNHICFILVHAGVPRIMDETLPQTYVHVVLEVSSRHKTHSLGHIPDSSVMGRQWAAHSTKEPHYERLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCD0</accession>
    <name>A0AAV4XCD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_411381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017434">
        <property type="protein sequence ID" value="GIY91620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11292" checksum="5A2C43D7BEB4E9F8" modified="2024-11-27" version="1">MLEIVVQECSNCCSRMFKLLFKNVLIVVQECSNCCSRMFKLLFKMSKLLFKNVQIVVQECSNCCSRMFKMSKLLFKNVQIAVQECWKKFSNAKEPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG39</accession>
    <name>A0AAV4XG39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_416321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017739">
        <property type="protein sequence ID" value="GIY94062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11031" checksum="5E12C8033C25EBC9" modified="2024-11-27" version="1">MADRYRTNESSAKNSERRKSVSLIRNNNPTRNKSPLPQPQCNQVIPIAIFATVNYYCLLKHYAPILLTGSRSADPFRRRHGRNKLFRKRKINFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHF1</accession>
    <name>A0AAV4XHF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_109921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017652">
        <property type="protein sequence ID" value="GIY93361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9429" checksum="81E2965BC3036A3A" modified="2024-11-27" version="1">MSPEKPNEEEEDDYCVIIKTTQRVRVPTILDRRGIERSSRPVPYSKMFLDEVHRRNSRISDCREDSDFEKANKSSNKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHM3</accession>
    <name>A0AAV4XHM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167043_1</name>
        <name evidence="1" type="ORF">CEXT_43101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017753">
        <property type="protein sequence ID" value="GIY94164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="17219" checksum="8BC23E505A9DF185" modified="2024-11-27" version="1">MLCDLLGSQLGSQWKSGLRSEWKIENAANVCKKWSNWKYCQEFYVGSYNEDTKKTNIRWPNKLFPEEQNRFILWFRCLVHQKLIIQLFINGLYAFNCMKYYIEDLQWHQYAVVSVCEELFPDDKELLENCKKHDQDKWDAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNF6</accession>
    <name>A0AAV4XNF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3736 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_139507_1</name>
        <name evidence="2" type="ORF">CEXT_235031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018070">
        <property type="protein sequence ID" value="GIY96642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042337">
        <property type="entry name" value="GSE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17608">
        <property type="entry name" value="GENETIC SUPPRESSOR ELEMENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17608:SF4">
        <property type="entry name" value="GENETIC SUPPRESSOR ELEMENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="764" mass="86624" checksum="36B0B563E9175EA5" modified="2024-11-27" version="1">MQHPCNPPQKPRTMATVSPLHQVVPPQPNLPSFEGANLAFNATSRTSSFAAALRKLAKQAVDPVSGEKDLTQISPVSSPVLSQGSLTPKRSVSNSQPPPPAMFLTNHQVSYASSSPPVMTIAPSRPVATHTSESRKVMDLSNVQSVNNSNVLSNGHLQDSLGVKMDSSKNVSRSSHSEKWDESNLPNKGLSGSTASSQSRPHATIAPLPRPDDSLTSSRGFQPYRGTEESRNTLPHHLSLFDHPHPAASYPYTPAFLPPPHLSHPAYRFDDPLYLERYSLLRPPVMPYPQPGMMTPSAFYPNSRYAADLLAQSLSISSANNTILNHERLKQEEERRMREKEIELDQSRSKEQERQREKEQKEKENREREQKEREQREKEKKEREKSHREREEHKKHNTNYSTSSKRTESPNVRNAPVIQCAPPTVTNHISIPNTVSNPIPLNLVVQASPEPLKKEAEIWTPWQQPSTNYPKENNNQEFAKHPVFRSQEVHRHHASKDNSTSDKVNMRFSPSSTNDKRHSSIQIIDPPTPIVDAKKHSTPDNTKRFDTIHHHITELSSKEHVQHEWRHEKLQKACTNNHRKSHESKKAKEDRNNVYQNHQRKVVANGAILKPTPFQNEGMHARLLESEKCRLEMNGHALPKTHTTNTINDRLVPPNFKTNHQPITGKEIVPQKPFNDFYNAPSLKSNVDLAPVVSKLDLDAKNLKKGDMKYCEDDAKEELRLKNFLIITKVPPKKFESNHSNLNSCNCWDLQHTSKEKKSNSTCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRG8</accession>
    <name>A0AAV4XRG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_551181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018190">
        <property type="protein sequence ID" value="GIY97617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10983" checksum="051A4A10720D5C52" modified="2024-11-27" version="1">MKHILTEFQAHSPSIKCELLVTRHVPKCLQISKFDHVLQDKFSPNRMVSKSEYMWFQTKTIDIISHFFSFSCLIRKARRILGQLCWDLELKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTA8</accession>
    <name>A0AAV4XTA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_662261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018284">
        <property type="protein sequence ID" value="GIY98391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11337" checksum="B89EC2E40561FA9A" modified="2024-11-27" version="1">MFFDESKEWLAASFASPINHMHEIPPCMQCDCRKTIYFIIFFSFLVVLCFFPFEMCLQLRDLCENGCFSEVVGRDKEFVNGEYSNFDLSTKFAAERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y190</accession>
    <name>A0AAV4Y190_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein outspread</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">osp</name>
        <name evidence="2" type="ORF">CEXT_399661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018583">
        <property type="protein sequence ID" value="GIZ00750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y190"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052223">
        <property type="entry name" value="Actin_Cytoskeleton_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17271">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17271:SF1">
        <property type="entry name" value="PROTEIN OUTSPREAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="28038" checksum="40204FD00B69D230" modified="2024-11-27" version="1">MFVWYVNILTAPILSERWQRRWFVLYDDGELAYSVDEHPETVPQAVIDMNCVLEVADAENVTGNPYALAVTCPDKIHFIKGMSKEESKKWFEVLSKFPRNTVCGKYKRNATFPCIKSAPLVKIDSVRDISPAPNLSNRRDTVDISNYSKQNGYVNSLNRNNLKQSAGVAFDPDDDVYPTKDTNSSPVVKNVQKSLICEEKKKQENSISLQNENNCLRNGVLDKSNPKTEDVKNYIKHDNRDVRKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y296</accession>
    <name>A0AAV4Y296_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_794611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001233">
        <property type="protein sequence ID" value="GIZ00979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y296"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ00979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13109" checksum="0288FB6B195480AF" modified="2024-11-27" version="1">MGGQTVIKTGNDITEATTTHADPGSALARPMHSTLARRSGQSESCLNPPDPQRVLEQRHQQLNRQRAPTHAAFAAPCYETCPTCFVPVMRHAARRNLYIIRAYFSIVFFPLKIYLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y326</accession>
    <name>A0AAV4Y326_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_652421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018735">
        <property type="protein sequence ID" value="GIZ01891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y326"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11754" checksum="14A42C277671C295" modified="2024-11-27" version="1">MLLRGRSDFLLSHPLTTRLIPSSFFSFLPSPRKLLRKATCVRSSGTVFVTRCVAPPRTNQSGESRQTSQHALRHEEVGSSALLVTHEFSPWHENELIASVLGLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8Y3</accession>
    <name>A0AAV4Y8Y3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_471341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018955">
        <property type="protein sequence ID" value="GIZ03473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8Y3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16515" checksum="8AE927BC738311B3" modified="2024-11-27" version="1">MAHDRYQKEKKAEGHGSNCERNTSIPLSLFAETAIPRRIKAVITFPKVIVRQKTISVISPHIHRLSVASSATIRKKSSRPSLTSGDTLLLTFPPGSSSHPYFWNYTFLHIMTNRGICGDEGEWEKKMTSCYISTIVMKVFSKNCFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE66</accession>
    <name>A0AAV4YE66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GATA-binding factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pnr</name>
        <name evidence="2" type="ORF">CEXT_528731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019089">
        <property type="protein sequence ID" value="GIZ04462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12493" checksum="1E52E4BC3D78399C" modified="2024-11-27" version="1">MAGHQSMVSQSGHHWSGSQPPSVHDHQQSTGYGISALTSGLNLAAQNSLISATSQAGGCDQNELNRAAGFSTFASSGHGYLRPEMPPHWGLIDPITECNTPTAQMEWLTISIKNYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M2R2</accession>
    <name>A0AAV4M2R2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_18191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019315">
        <property type="protein sequence ID" value="GIX66490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M2R2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7815" checksum="85CAF376A0229A10" modified="2024-11-27" version="1">MKSRVKCNTLGFNKSSRSFAPLGQAAACLRHVSRFRTGKNFLLLFADSPLRRNTLPRPNACSRSYRTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M592</accession>
    <name>A0AAV4M592_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_259107_2</name>
        <name evidence="2" type="ORF">CEXT_438831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019407">
        <property type="protein sequence ID" value="GIX67508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M592"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13685" checksum="9998B7905411F014" modified="2024-11-27" version="1">MQTSALMSNITSTEAVCIISNCLQQVRQGQPQFTGRRRREVNETHKLIDDVGEDSATNKEPDEVEQPEENVKLSDALPSMKEFLNLYTFIDERSAKELEDQVVDRIEVTVAEDDEDYDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5V5</accession>
    <name>A0AAV4M5V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_10431</name>
        <name evidence="2" type="ORF">CEXT_56051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001896">
        <property type="protein sequence ID" value="GIX67733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="1">
        <location>
            <begin position="133"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="271" mass="30026" checksum="8947F4068681D216" modified="2024-11-27" version="1">MTAFHPIQSTNFPILVAHLCFKEMWRLLPSQHPIRGNTSPSSLGFGGTIVETLLRGIYQSLGCNSDQNLARLVLFPATTHEGVDAVFRFVEGRQDLGNEFFALLNKLSFAPVHLKSHRGFALFQGGHKLASEIKIAFVDLLKYMGITSDKIVGYGIGELASTYSDGCITAEQAILAAYFCGKSIEQVKFRMNGTSVTGFKVPAARSQRWINSSYPEPKNRLANAEYFAHRLISVAPSSEALRQIPQRALVVEVGRTYTTHCKWSISFSPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MC21</accession>
    <name>A0AAV4MC21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_564971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002096">
        <property type="protein sequence ID" value="GIX69939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MC21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12898" checksum="8082E0E78D3A09D4" modified="2024-11-27" version="1">MDSIQHRVSKIIIGAVSSTNNNKVEQECGLPPLENRRNLATIKFTNRFRSNNMDNISTTVFKEWNDSTRLKRSSTLQLDTDIRSLINLEHSSLDFVQNHLFSENHQVKLSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDW6</accession>
    <name>A0AAV4MDW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_283341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002154">
        <property type="protein sequence ID" value="GIX70612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7816" checksum="076C394B78EC35EE" modified="2024-11-27" version="1">MQDESCWRSSLSFKMLWRIDANILLIDFRAHVTSASCDALENAADCFTNKSSCRFVCYLWRVGFKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFR7</accession>
    <name>A0AAV4MFR7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mutator-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_43574_1</name>
        <name evidence="2" type="ORF">CEXT_297161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019701">
        <property type="protein sequence ID" value="GIX70834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049012">
        <property type="entry name" value="Mutator_transp_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20700">
        <property type="entry name" value="Mutator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mutator-like transposase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="411" mass="45775" checksum="79EDCEC1BE6B8DC8" modified="2024-11-27" version="1">MRREKVCDETLLECDGQQNKGKDIHVVFLFLTQFVNGTSTISESKLSENLKSYGFNQQESVSNSLVGNRIIDIETLSNVFSELSCPKCYNNDICLFEDSKYGLCSHFTLKCGKCDFLKGFSSTQKTLNVPEVNARFVYGMRQIGKGFSSAYKFCATMNLPALSKSGYKKHEHRLLKVVTDVAEDSMCNAAKEVAETLNRDECGVSVDGTWQRRGHTSLNGCVAVLSIDTGKSIRLGSYVFVLPHLQKTTKKMPKNAEYVTLKADHICQCNYEGSSAKMESVGAHRIFSRSVKSRQLKYTTYYGDGDSKGFLSVQNIYGINSVCKLECIGHIQKRVGSRLRKLKSKTKGLSGKGKLTDAFIDKLQNYYGIAIRSNVGNLKNMQQSVISALFHCASNKNKSMHGQCPIGKESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKZ8</accession>
    <name>A0AAV4MKZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_515701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019850">
        <property type="protein sequence ID" value="GIX72470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10290" checksum="1D2500EBE3433D8F" modified="2024-11-27" version="1">MPPKFKSGKPMQSGQQYRDEARSDSTQSFKQLSLMEECDCPGECNNENHLAEFSSFKQHDPHESRTSPKFKKANQCSPETTDSRILHSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMG3</accession>
    <name>A0AAV4MMG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_487461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002389">
        <property type="protein sequence ID" value="GIX73221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8607" checksum="D56044E41112B492" modified="2024-11-27" version="1">MMDRNLKIGEHCDSCSQGLGQLTTLIYRNRPGRINGKGMATFLACLVLIKWITDSERHGGNGAVTFAVIHCICWPKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR52</accession>
    <name>A0AAV4MR52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020101">
        <property type="protein sequence ID" value="GIX74833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11182" checksum="D09C77B4E110142E" modified="2024-11-27" version="1">MKFKIDLKRYKSCFKTKTDSQPHHLNVLLVQFNCLTKTTFQKKQNTMYGSTPGKIVGQYPCFSPATANKSLCPICKYLANTPLNTMDPAGKVNSRQYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSA7</accession>
    <name>A0AAV4MSA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein F54H12.2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">F54H12.2_138</name>
        <name evidence="1" type="ORF">CEXT_645611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020160">
        <property type="protein sequence ID" value="GIX75331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14379" checksum="C35A98B004E4DD3C" modified="2024-11-27" version="1">MFYLEKDLETAAKSRSKEAGESLARKAINHVQSMIGDAGYKVVLEKINLLVRKVRFSPDVIMGHEKALENNAAKYYLNRVLCKVYSVPQGRIYVDGQPKPHAPLELNFDKNNYIKGYRSLFSLTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N1A9</accession>
    <name>A0AAV4N1A9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_313721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020372">
        <property type="protein sequence ID" value="GIX78019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N1A9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18596" checksum="40E2EEF3479871A6" modified="2024-11-27" version="1">MAEPVRRVQEVLERRVRLYLLIDLLWLQDSFRIHGLLATTGLQKTEALFTCMTFLLLKISHGHCVTPSTIPDPGLSSSNHYASCTVWNLSALQALLFRTPQSLVYTFGKHLFSIVKLGRDYRRKIEKTASVGTPDWPGSSSMLFMKHAVKYQLILVEAQEKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N591</accession>
    <name>A0AAV4N591_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_184311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002938">
        <property type="protein sequence ID" value="GIX79440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N591"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16252" checksum="846F8BC28E1746C7" modified="2024-11-27" version="1">MIDVLVKCRSPKLPLTLGKRNPELGCKNSKPNFLCQYEISVANLNYLKTNKPELTFKDEDEDESGSPKVQTISSKPRLSLIKISLVTESVALDKQAYLARQWWFPPNSRQSEENYLNVSIDGNAGLNTIKKGKKIIKKRRCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N749</accession>
    <name>A0AAV4N749_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_578851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003045">
        <property type="protein sequence ID" value="GIX80548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N749"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10178" checksum="FE76A0790CBAAF83" modified="2024-11-27" version="1">MQKENSFSIGEGIVFIHDMTSPPPFSHGLSQIPVSRTPVFSSIPLPNFNASLVHCACANSICIHLYRRCPAVARKCLRASLLFLGENEKCFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9W6</accession>
    <name>A0AAV4N9W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_593101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020617">
        <property type="protein sequence ID" value="GIX80703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12396" checksum="E0B8E7ABB82A0AD8" modified="2024-11-27" version="1">MKSHINNTRRRSLPKKDALLISLTQTGQNGEGGKKKYDFGNRLRNRKESKHTLKKKKKKKIVTEFCPLNAVAECERFQRWLVEGSTFLWDNGLKSLNGSRAADVCYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNR7</accession>
    <name>A0AAV4NNR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_96861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021144">
        <property type="protein sequence ID" value="GIX86462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11897" checksum="DC2016BE8CC5C0DC" modified="2024-11-27" version="1">MGRTKKESGEGMSCSCAPSAHDEMCLVIEMLLEGRRFKHCLPLKHCELAESIARGRGGRNQDINSSHYDGSRYTLFTTKKARYQHMARVIKLDLAAIFVWKRCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWA6</accession>
    <name>A0AAV4NWA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_172408_1</name>
        <name evidence="2" type="ORF">CEXT_363921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021342">
        <property type="protein sequence ID" value="GIX88613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12094" checksum="CC9A47707CCDEF77" modified="2024-11-27" version="1">MGGGKRGTAKVGRREREGELNDKFSNKGSRQGSLERIIDSSPLSKAERKKLEKYNKFNIDLQALLAAVEHKQLDRARGILETTNVDINRSFFRSCLPSLQYFLPSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P041</accession>
    <name>A0AAV4P041_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_75641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021411">
        <property type="protein sequence ID" value="GIX89264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P041"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="9941" checksum="97AD5B33AE7A125C" modified="2024-11-27" version="1">MANVGRCSIVLVTDQEAGGQGVVRDHHHFRSANVTNNAITNRESKKLSILPLRSQAFSTPEELAKTVPFCTESGTLGHNPSVSPLSGLPSYPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P084</accession>
    <name>A0AAV4P084_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_228711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021401">
        <property type="protein sequence ID" value="GIX89186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P084"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12554" checksum="8053549C4E3CEC88" modified="2024-11-27" version="1">MALTSSRWMRLAMEVRRFPPPEPKMPPIMPRGEDAQSSRNRVTPPSQAGCCATGFTAKKSNPGSLLASMVQGAPQLHRWSLRGIPQQSSNSSKPGFQILTLMLPLRRFMFLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGY5</accession>
    <name>A0AAV4PGY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_654641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004674">
        <property type="protein sequence ID" value="GIX96662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15398" checksum="6C7739A8E0982DE8" modified="2024-11-27" version="1">MSFAYRYREKKVHIVLVKARMGDGFSSGFIAAATRSWVWWPQRTLHSIVHTARPPTPLYFEQIETLTTWSSPCSGSIAIHTQLIAQGSLRLSESYFLHVVIVSIENGLHRSTRVWHLSAIPRDYWRDFPTYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHJ2</accession>
    <name>A0AAV4PHJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_711941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004711">
        <property type="protein sequence ID" value="GIX96917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="18893" checksum="BD0FB26006A8144D" modified="2024-11-27" version="1">MLGFPARLGQRRVVFSLFVGYRSWPGVCRQPLHQDSTACAIPNHCKHPWGSRMAVARNSRIILSLNISHQGQNWYVCIVPVDRPSVCPGPPLDPPRVRLKEVSGSASRCTNYIFESWDKNKNKPVAECHASSALLSEHSRSLEPARTSGYSHTAITITHQKPARAKILTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHM9</accession>
    <name>A0AAV4PHM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retrotrans_gag domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_64930_1</name>
        <name evidence="2" type="ORF">CEXT_750641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004665">
        <property type="protein sequence ID" value="GIX96594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="270" mass="30110" checksum="A0A3C024B8489455" modified="2024-11-27" version="1">MADPMKYELSLRLRSSRMEPGSRPIEAWNDVNYDAVRVRAYKRWWIFQLPSERVKDFASRLEGVAHKTFGDSSVESGDMSQNFRAKMILSQFLAGLQPMIKAQIVIINPETFEGAVELRERIEIAQEMLVPNVNVLESGNRVHDQVLDAVQASGDTLAKTLNLVNRQLEHLNSRMDKIEAETKSGNGGNWQQNSSPGAAANPPFFFLFSISISPSSSLSQKAHISHPPPLISTNSDRVKADVIQASIDRDPGSIRGERSLKARAHQGEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJS9</accession>
    <name>A0AAV4PJS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine protease nudel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ndl</name>
        <name evidence="6" type="ORF">CEXT_791541</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004824">
        <property type="protein sequence ID" value="GIX97832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="312"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX97832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="540" mass="61102" checksum="20DC46E62551769F" modified="2024-11-27" version="1">MPIRQSFWCTKFSWSFVVFVTVMSTFFVGIVFLLIYTIPSKSQPEDLDHSKAESVWLGGSNVTFPFEKDLWLNVSLIGPCPRNYFACNSSRKCLPLGKRCDGTVDCPRAEDELNCVCAFRMSLSKFCDKYPDCFDESDESFCSYCPVGSFNCGDGRCVNKSKVCDGVVDCENYMDENFCFRLSPDGALNETHKPDPISTNNVEIVKTGFLLRNKNGIWYPMCANPYDNMQDALASFACVSITANPLASNAYHYRRFDFQHRQRFTDYIYHQQGKFLQWRGCLTSSGIFIRCNDARCGLNPHHLLPKKPMARIVGGKNSNPGNWPWHAAVYKNGTYSCGATLISDRWLLSAAHCFLNHRYNYYEITLGMLRRRSFTPHQKTYRIDRVVPHPKFNIVTLEYDIAMLRTFEEVGFDFWVRPICLPNPGWVESSGSFCTAIGWGDIGETKDNSDDLQEVHVPLTTTCKRNLDRWLCAGFKEGGRDACQGDSGGPLMCLFEDGLSWYIAGIISGGTGCARPEHSWYVYQGGLLLGLDKSCSSVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PM77</accession>
    <name>A0AAV4PM77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PO21_48</name>
        <name evidence="2" type="ORF">CEXT_488611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004734">
        <property type="protein sequence ID" value="GIX97055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PM77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="19951" checksum="99897F2242D29B73" modified="2024-11-27" version="1">MKCVAQRFKEWLLRYDVLSPSQKVCMPHDVVLEHNFLLHKRFEDARTMKRDLCLAWLHVTNAFGAIPHRAIDDALRAAQAGDTFLNLVNCVYDDCRTKLLSSEGLSESIRIGAGIKQGCPLSGLLFNLCIDPVLRQVTTSSNKHNVLAFCGRHCPAGRQPHFAPKLHQYSPHSFIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV07</accession>
    <name>A0AAV4PV07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">DDZ39_07815</name>
        <name evidence="1" type="ORF">CEXT_716401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005241">
        <property type="protein sequence ID" value="GIY00945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052560">
        <property type="entry name" value="RdDP_mobile_element"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688">
        <property type="entry name" value="ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11616" checksum="9605034DF518417B" modified="2024-11-27" version="1" fragment="single">AKDLKLSLNADKTNYCVFSTDRKHRSTFNLDIKINDSPIKRIEFPTYLGIAMDPELRFTRRIEHTANKALRKLSILRKLCGTTWGSRPKTVKNAFCSSLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWM1</accession>
    <name>A0AAV4PWM1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mcm7-b</name>
        <name evidence="10" type="ORF">CEXT_769491</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01005190">
        <property type="protein sequence ID" value="GIY00537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000826">
        <property type="entry name" value="Replicative DNA helicase Mcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="9">
        <location>
            <begin position="27"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY00537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="41479" checksum="720337EB0B22FF33" modified="2024-11-27" version="1">MNKTEDDELEDRELTQAEAEEILNTYNYDMMASSISPEIFGHHDVKKALLLLLVGGVDRNPNGMKIRGNINICLMGDPGVAKSQLLSFIDRLAPRSQYTTGRGSSGVGLTASVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMMDSDRTAIHEAGILTTLNARVSILAAANPAYGRYNPKRSIEQNIQLPAALLSRFDLLWLIQDKPDKENDRRLADHITQVHMHCRQPEANFDPMPMNLMRRYVSYCRTIQPTIPEDLTDYLVSAYVEIRKEARNSRDMTFTSARNLLGILRLATALARLNLRPSVVKQDVDEAIRLLDMSKASINQTQQFGGRVQTATDQIFHIIRDMISELTVELLKWLMPKNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PX37</accession>
    <name>A0AAV4PX37_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="8">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RDR1</name>
        <name evidence="11" type="ORF">CEXT_558041</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01005223">
        <property type="protein sequence ID" value="GIY00779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PX37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058752">
        <property type="entry name" value="RDRP_C_head"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26253">
        <property type="entry name" value="RdRP_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 8 11" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="RDRP C-terminal head" evidence="10">
        <location>
            <begin position="217"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF26253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY00779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="572" mass="65978" checksum="68910F670687A5E3" modified="2024-11-27" version="1">MLGVIDETYTLEYGQIFVQYSEELGNRESHTKILKGIVVVTKNPCMHPGDVRKLEAVDVPALHHIKDCIVFPAKGERPHPDEMAGSDLDGDEYVVIWYDPLIFPEQNYPPMSYPPNPEKTHQGPIQVSDMIDFLCEYIQNDNIGVMANAHLAWADIHQQGIFSKVCMNIAKKYPLVLDFAKSGHTCYLSSEEKPKVVRNLEACVSKVDVVNLEHEVDEHLIYEGWEDYAKSAEVHRLEYTKRVKNILKKYGLRSEAEVLTGYVGKMNEYTLNRYERDNALSIARTYIMDAIKRFRMEFNKAFDNERRANNVKSNFQEMKYRMASAWYAVTYRRKDAPLLSFPWILHDLLCEIREKNLKLKRLPCSIPESSFIDSSDGRLLQLRQQYLFCLDQNCYCVLVLLNSVQDWMTKSTLNLTMSAGDSFCLTCFDRIINEFLKTLVPQCCCFGKSCCCANTCSPTKLILEFLKFYATEISDNEEATLDDNPFEEGDPIRVSVTEDFEVLLTHHRAEVLSQLKKLSGVKDIFISAEADQRNNWYILVQSIGKGWQRWNLEELIMDKDIAKIIKSLLKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1M3</accession>
    <name>A0AAV4Q1M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_384491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005531">
        <property type="protein sequence ID" value="GIY03031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10398" checksum="DBED4A93123B2AE0" modified="2024-11-27" version="1">MESTKKLQEQLGCVIGKDYPFPIVDHDKVRIENLRRMDAVYKAKKEMKDQDKKVPVTKSKKSDASNEVSKGKHSLDTNKDVKISKFFKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QE81</accession>
    <name>A0AAV4QE81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_793251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006107">
        <property type="protein sequence ID" value="GIY07435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QE81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="20043" checksum="188DB75ABB93A6FB" modified="2024-11-27" version="1">MADNHELPVRENIDHCILYAEWQTIMNYFSMHSIMNYQFVKILITRILYAEWQTIMNYFFYTFNHELPVRENIDHSYSICRMADNHELPVRENIDHSYSICRMADNHELPVRENIDYSYSICRMADNHELPVRENIDHSYSICRMADNHELPVRPLVFYMSNGRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QH17</accession>
    <name>A0AAV4QH17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2_80</name>
        <name evidence="2" type="ORF">CEXT_737111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006281">
        <property type="protein sequence ID" value="GIY08715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QH17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Immunoglobulin I-set" evidence="1">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10001" checksum="290F91BFBB988617" modified="2024-11-27" version="1">MVQKDGVRLVPVSARPGVILLSGSLYFQQVNVRDSGTYVCVVNNSAGEKRMESSLTVTGSNFHKVHKSFSLDAFISADELRHRSGLQCSWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQR9</accession>
    <name>A0AAV4QQR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_697741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006551">
        <property type="protein sequence ID" value="GIY10671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="201" mass="22912" checksum="9B736E96D558EC04" modified="2024-11-27" version="1">MSSTNKNLSHTDGIFRRSMDFLLVFQSLSRTSAFPFKAPSHRGERRHAAGKKIFRPVHSETSEIALHLRWERALKEPSGLSLTAAYPMVALACAVDRRAYQTAECSRVLPPDLNRGKTKDFWRLSIVLRATRARRHAQALVRMSFIGWNELLPKIPDSFNSLWFSKRTVSEKEHKNSLAVVHRWTSFVHVTTAREGIACPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT47</accession>
    <name>A0AAV4QT47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_26321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006565">
        <property type="protein sequence ID" value="GIY10818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10706" checksum="347231E4237474FE" modified="2024-11-27" version="1">MSGLYIYKIHNTAGVKDILPRCKFHKAIKHKGLDLLRRQFLFIVGCTQTFPLQLIAHALGPAKQKTTRFKNSSEDISDYYLGIKIKKAEAAEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWM9</accession>
    <name>A0AAV4QWM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_57951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007015">
        <property type="protein sequence ID" value="GIY13905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16693" checksum="1C85673F7596DFA9" modified="2024-11-27" version="1">MLLLEEWLSGITIKIIVSMYEFYFEISSINRDRKKGNFSKLPKRKALYAAADFLPHNNSGRVDTVVLTAAPSTPYLVEIENDGEQTLPLTRPFQFSEVTPSGCQGWPSDEWWIENASIGFEKDLNGFQSKSCHNCKFFKTLTFNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXI5</accession>
    <name>A0AAV4QXI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_229041_1</name>
        <name evidence="2" type="ORF">CEXT_407511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006857">
        <property type="protein sequence ID" value="GIY12830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="260" mass="28442" checksum="84E4B77C0D591481" modified="2024-11-27" version="1">MPNNSNNVQSSFSSSRIGSYTATSPSMSGMANSGLGLDFKLTEPSPAAQTLKQMAEQHQNMQQKQQLGLGVSPRSPFGSETLSDALSNIRTNCLSRSPNSMNTLQNSPTGMYQPMGYPQQQQTYSAPSSSAVKQEIVTPNTPMYPPNMTQHISEMELHRRRQQAMQMQQNQMGNLAVPPFSHSPDQKRQYHGNRQLPMYNDPSPGHQPNDGGASASNSPVPHHSGQFLRSVSTPGVTPPLKDLYPALPHPVDQCIRIKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1F1</accession>
    <name>A0AAV4R1F1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_761141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007334">
        <property type="protein sequence ID" value="GIY16133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1F1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11337" checksum="DDE89CF536594EEB" modified="2024-11-27" version="1">MTLRFFLTCHPFTSHQAGQMRTRYSYSCLMDGSCRYPVDTGNDRVTARRNRSPSLTCPAKAYFAGVIKYPCLCLDTTLVEQCDTSLSQNNVLGINIKTSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3I3</accession>
    <name>A0AAV4R3I3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Lrrc15_1</name>
        <name evidence="4" type="ORF">CEXT_796191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007211">
        <property type="protein sequence ID" value="GIY15186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3I3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050467">
        <property type="entry name" value="LRFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45842:SF22">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45842">
        <property type="entry name" value="SYNAPTIC ADHESION-LIKE MOLECULE SALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY15186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="22061" checksum="80A0B9F3774C5215" modified="2024-11-27" version="1">MRVPLMNARESHDPVRDTSMCDAGVAKGGWVCFWMRAAVRDSGGLAKIGSEDQEVLSRNFDNDEKRNGENHDVAVFDADLIASKHSSSYLVCPSSCYCDDKGEYVSCVGDGLWRFPEDIPNSTVRLELRNYLVSELLQQDLCDLVVLEELKLQQSHIETVDNATFASNPKLEGLDLSQNSLTSLSSSIFTDLSRLRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5M2</accession>
    <name>A0AAV4R5M2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_656371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007404">
        <property type="protein sequence ID" value="GIY16717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5M2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="301" mass="33514" checksum="F904BAEFE797C02E" modified="2024-11-27" version="1">MNLTVRRQLSVGQEMDLPNNIGEIISIALEQYNELVNLTDTRDLKSAAKQAFRKKATALLKKITHQSNLIAQMEGAVQELRNTPRVCKHAELNTAPKETAKTDKSTFASIAKRNTPPPKKNNTALNTSKKQHLAVIKPKDVTSNSADTKSFIKKSIDITQVKVGVKKVANIKKGGILIETVNEADLEKLLKELEQNDSIKEKYKVGKPEKGTHSSSASECLRKQKKRLCQKSIKHHCKKIAAKSRLSTPIKVNVESIGSLKQPLAFTKRNMDVGLIWMLGVGLKTLLHKKKTDRPLTEICQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RE51</accession>
    <name>A0AAV4RE51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_780511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007618">
        <property type="protein sequence ID" value="GIY18387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RE51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14663" checksum="F8F714E61C101FDB" modified="2024-11-27" version="1">MRMALMTDPYPAQGKLPANDDDVLLVLSPALRSLADHDPDSKGKVMREKENIKFITEGRGQTTVAPIRNIFIISPGMRAERTGFRNLFGAIRMRNEFSLLFASSSSSSVWCSRRMRAKIHSRSLFTMSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKN5</accession>
    <name>A0AAV4RKN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_665051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007940">
        <property type="protein sequence ID" value="GIY20825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8765" checksum="7750246B538AAFF4" modified="2024-11-27" version="1">MKDSQLSELGRICAKSLLVNLEAKGGFWRVKQGEGVEKGRKGVFESNHAMDVNEAGCWLEPIVAPLNSRYLTTFPSQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMU2</accession>
    <name>A0AAV4RMU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_756201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008194">
        <property type="protein sequence ID" value="GIY22780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15663" checksum="B01E10985312BE0D" modified="2024-11-27" version="1">MGSLNNFYFGGMHRDISMVYQNIKKIIQHLKEHKLEELLNDNAVYFFKTAVQYVNMKHVKFHPENDFEEIWLIGNDCEERDFGKCRRMNSSWVTQPEKVLNGGDHDLDKSGLVLECTCLLFTYRIHSCVATRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNM2</accession>
    <name>A0AAV4RNM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Disco-interacting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DIP2</name>
        <name evidence="3" type="ORF">CEXT_121561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008049">
        <property type="protein sequence ID" value="GIY21702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010506">
        <property type="entry name" value="DMAP1-bd"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51912">
        <property type="entry name" value="DMAP1_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DMAP1-binding" evidence="2">
        <location>
            <begin position="4"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY21702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="289" mass="32271" checksum="3432DA0598EF8548" modified="2024-11-27" version="1">MFVEQPTLKLILSLQRATAFSGLIVVQVSLRDITQKGYEKKRAKLLAPYMPARSTGAASPSTRAKKELSEDLLEMKVGIIQRSDRKLSNKHLLQCKIGQNRQSQCHRSEHQLWLLHHSSSDDDSAVNEGSTPEQEHLPTHNIHQATTSQSDTSSTSSTRETPSPQQWYNGRPNRVDDYWVHTSCASPMTNLADVMQNLTPSLSVQPDVTNTSAEVTRWTSADHVNRPKRRPLPEFYVDDESDLETKQLDPNAPRPEGNLMTPITGEELLVPSGLPLTSEAAIKDMGQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQ97</accession>
    <name>A0AAV4RQ97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_530991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008157">
        <property type="protein sequence ID" value="GIY22490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQ97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21852" checksum="41856161B61C8923" modified="2024-11-27" version="1">MLYSNANPTAETNARHLFTTVIRASVTTARPLEREVFWDRKRTRVKRSQCFYYFLQKQMGKTFFFPGVTSPFNTFNGKRKSTALNTYLIILPTELRVNHSSTLSFKQISTISSKVPSHCEPSERQLSGKNYVRGLFMRRNWTLPGKKIKFHFNTCAAVWLNVRCGVTQASFFLSLVEQMPLHQDMSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQI8</accession>
    <name>A0AAV4RQI8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dipeptidyl peptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CTSC</name>
        <name evidence="3" type="ORF">CEXT_166881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008335">
        <property type="protein sequence ID" value="GIY23985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.128.80:FF:000003">
        <property type="entry name" value="Cathepsin C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.80">
        <property type="entry name" value="Cathepsin C, exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014882">
        <property type="entry name" value="CathepsinC_exc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036496">
        <property type="entry name" value="CathepsinC_exc_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08773">
        <property type="entry name" value="CathepsinC_exc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75001">
        <property type="entry name" value="Dipeptidyl peptidase I (cathepsin C), exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043315846" evidence="1">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin C exclusion" evidence="2">
        <location>
            <begin position="20"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY23985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16978" checksum="05F53C94B0EA77CD" modified="2024-11-27" version="1">MALLYFSALLTLLFVYSRADTPANCTYEDIRGVWTFYEGERSGSSNVNCSTFKGPVTYISKVKLDFPDVAVDDVGNKGYWTLIYNQGFEVVINYRKYFAFSKFKSSSGGNTTSYCDTVLPGWSHDVLGKNWACYNAQKVAPSVGVKSHQNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSZ0</accession>
    <name>A0AAV4RSZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_624951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008546">
        <property type="protein sequence ID" value="GIY25448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="256" mass="29224" checksum="7F4BD86008C6E78C" modified="2024-11-27" version="1">MQVMGTPGFRSQRPFISRKAAVATKHSGRDARLQARRKGQRERALTNYYKMPFTSDPVARKIERTRKHWPSHRKRTSYSIKPSIKKLIRYGTAFKFPNTSIISNSNIHPTALSNTRTAETRRRYSQQQTVIDRGSVKWLLVTSCENETQLLLMHYSSRQHSFGRLGSFSETRAPGRVPWAKIPQFYSARLTRVSSGLILFKHSCPLANCDSRRPPAPIRVCSFALLRACFYCSTDSGRIRIAQHPVTDAAIELKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTX2</accession>
    <name>A0AAV4RTX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_466881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008499">
        <property type="protein sequence ID" value="GIY25185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15598" checksum="559A47861CC578A1" modified="2024-11-27" version="1">MHETRILIRLPNVIQLFQDPKQRVVCGLRGVCEIATCLPRNDLLSKGSVNEVRLCDIGVVAASPPSLKIRPRLKKEFRTLGFVCATLEWLLQRTKSQRRPRLKEFRALGMSSEWGGYFGVINARDGGVFRDLIWYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV45</accession>
    <name>A0AAV4RV45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein hu-li tai shao</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hts</name>
        <name evidence="2" type="ORF">CEXT_604951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008572">
        <property type="protein sequence ID" value="GIY25753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014069">
        <property type="term" value="C:postsynaptic density"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF3">
        <property type="entry name" value="PROTEIN HU-LI TAI SHAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="27881" checksum="F0DA577B640D0118" modified="2024-11-27" version="1">MHSKITAGPQSSLLEGVTWEEIKKMQDGQLASGDQVVIVGAASKGIIQREFQHNAMVYKTAYAKNPFDNISDQDLEDYRKIVEKKQRGEPVEDDIPDHIKPLLLEPVLVTDGQQVSSVQDLNTPPQSPTSPCSDEEAKSGGSVQRSLSARLSVEAAEEIREKSFQRRTLSERKPKSKITADVTLNGEEKLRSAESGEVSAASRSSKESSPVKEVGDESPKKDKKKKKGLRTPSFLKKKKHKKEKEDKEKVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S5R9</accession>
    <name>A0AAV4S5R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_171581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008874">
        <property type="protein sequence ID" value="GIY27911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S5R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13672" checksum="5DDDFC05F2DF5A93" modified="2024-11-27" version="1">MEKSTYKSENPPSPSAFFNLNAEDAISPETLSCVTFRDSGVFLFKNLFFALKNVSNLKEEKGYVKKKNGVGKSNSVKLAGFAPGAKRTSKIDKMNHEAPSRDEGANCLIRWAIKCCAFIRQMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S709</accession>
    <name>A0AAV4S709_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_287721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009010">
        <property type="protein sequence ID" value="GIY28966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S709"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044022605" evidence="1">
        <location>
            <begin position="16"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9250" checksum="2716B07AA8E50BC8" modified="2024-11-27" version="1">MKVFIVLLMVAVTFAFEIREQPCPTNKTWGDFGDCPPSYVLPDTSCWEIEIPLPIASNQRTAHKPRILYLKQYEESLKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S831</accession>
    <name>A0AAV4S831_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_40601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008910">
        <property type="protein sequence ID" value="GIY28143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S831"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="15426" checksum="4970D1CB82C4F06B" modified="2024-11-27" version="1" fragment="single">IGISEWRPEGFEVLQNANTPHGKDRYVVERERERGERERERERERERERERGERERERERERERRERERERERERERDQEVCASFQNRKGNPQSRQLTERERESKRETRSVCLIQEQERNPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SC98</accession>
    <name>A0AAV4SC98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_417911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009276">
        <property type="protein sequence ID" value="GIY30771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SC98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10293" checksum="8318A7DD15D7B129" modified="2024-11-27" version="1">MVDFPALIVSADHSWFIWDTQSGLLGDILIIHNGVGLGLRYGQCWCSRPPQTCTRTVDFPGLIVSVDHAWFIFDTQSGLLGDILIIHKGVGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SH99</accession>
    <name>A0AAV4SH99_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Retropepsins domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_159281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009537">
        <property type="protein sequence ID" value="GIY32729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SH99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10675" checksum="671175645CA81689" modified="2024-11-27" version="1">MIQKGKSLNRDRTKMSNAIFDWEIPKGETNGKLSRIDLRVGSRKFQGIMDSGAETTVQRKSVIQEYLLSINENNLRPEIGPFVEAKRTNIPVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ST41</accession>
    <name>A0AAV4ST41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_793491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010048">
        <property type="protein sequence ID" value="GIY36434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ST41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10961" checksum="EDC637A286C3ED41" modified="2024-11-27" version="1">MENKSPDGDFALFGHTKTIPHQSGQQKRQDTPFENKHPRRGWWVGVVHPRNRREVLSRLTGEDNRVTFRHGAECLWAKANEMFEFSRLVDSPTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3R4</accession>
    <name>A0AAV4T3R4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rad50/SbcC-type AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_575181</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010602">
        <property type="protein sequence ID" value="GIY40379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3R4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="10">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY40379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="35" mass="3809" checksum="D0AAD116554E64CF" modified="2024-11-27" version="1" fragment="single">MSITGIRSFDPDTRQVIGFFRPLTLILGPNGCGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMX7</accession>
    <name>A0AAV4TMX7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_399181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011584">
        <property type="protein sequence ID" value="GIY47485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043775094" description="C-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="22223" checksum="170C816E2109B64E" modified="2024-11-27" version="1">MNCPSSLWILVLLKVIESCPSDYFKASEDTCLHLAQPTSRISKEEYCNQKGGELFGRPLTPDMKDPLANAIARGSSNGFLTEHDDTWVLSMKRTIHFSKVSTRCGNPFYQRKGLWNTCESRNLYYSNYDGRCLAVLKDYKSYKKGLTSCPEGHLMKVKKESDLEEVVQAFFNGRFFGGVYIGLEKKNGKWQYING</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TXG4</accession>
    <name>A0AAV4TXG4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_604751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012056">
        <property type="protein sequence ID" value="GIY50995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TXG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8296" checksum="9B4A44CD39D72EA2" modified="2024-11-27" version="1">MNWQFHFESNRLHLGQEVEGISQAICASLDRSSPGERKCREAPKAAKEFPSQFAFISCKEVRSEWEFEFGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYK1</accession>
    <name>A0AAV4TYK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Synapse-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SYAP1</name>
        <name evidence="4" type="ORF">CEXT_296921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011961">
        <property type="protein sequence ID" value="GIY50311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048172">
        <property type="term" value="P:regulation of short-term neuronal synaptic plasticity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF6">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="3">
        <location>
            <begin position="177"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="308"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY50311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="483" mass="55658" checksum="5C37E6B246613EF3" modified="2024-11-27" version="1">MDLLWKVSSKAKEMLSHKDDVSGNPEDNKAETSASFAAGLGNEKPSSSLSLETQQGNSDRDASSESEGIDSEHSAASPVSKELNLDGSEDAERSSIKMGISAEILKMLLTRQWNQLSHLGVFYMALLIKLVALLLKLLNNECPPPWAGTEDEEYVKEQILSLSADKRNFLRNPPTGVMFDFSFDSMYPVAEKMLKEDPALEKMRFEIVPKIINEETFWKNYFYRVQLVKNSSKLNKSCTAENWQCVLSIHIKISFLGKGRKSDLIEFATEIGGTIPPETFIVDIKKIITSNKNYDKEFIKKDFERIIQKRIKKEENENQRQIEIEEQEKQRQIVIEEREKQRQIVIKEREKQSQVEIAEWEKQRAFELEKLKLQNENKVMFQMPTEYKTIADHDVGPDSDATDSPNHEFVSDAFQSSQVSEEDIKHGMKMLGVTEKNTKDDDWEQEMQQELQEYEVVAEGNDDDPDWENEIEQMLDDKVKYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8V2</accession>
    <name>A0AAV4U8V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lysophospholipid acyltransferase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Lpcat3</name>
        <name evidence="8" type="ORF">CEXT_466941</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012478">
        <property type="protein sequence ID" value="GIY54174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071617">
        <property type="term" value="F:lysophospholipid acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF14">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY54174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="18897" checksum="4025EDD3AD34C6D7" modified="2024-11-27" version="1">MAVIEAGSGGPISYFAQLLGASEPAIRLLYTVILGYPLALFHRHYLFGKSPALQNLFFISCGLSFGFYNYGYDILHSVLCVFIMYFILITIGGTFKSVIISFVFFMGYLLAGYYFTGTDEYDIKWSMPHCVLTLRLIGLSYDLHDGQKPQEKLSEEQKKTALKGVLHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBF0</accession>
    <name>A0AAV4UBF0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012608">
        <property type="protein sequence ID" value="GIY55113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10937" checksum="54D2455A0D863755" modified="2024-11-27" version="1">MKTTNKNDLIQRDPVVCSLYFKHKVDYNIPFKLGAKYMLTCNLNTSDKLVNGAAGLLRKVETCTMKGVAKLGIKRIWPEFMEGPKSASKHVQSLFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEU2</accession>
    <name>A0AAV4UEU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_31611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012748">
        <property type="protein sequence ID" value="GIY56251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="755" mass="83757" checksum="B101EDF63EACAD18" modified="2024-11-27" version="1">MAAFKSSTELKDARSTDQINMRIGVGWGDSVAHWLVRCCVRVRWPRSNRSTELKDARSTDQINMRIGVAWGESFVVSCSSLVSEVQCEVRCPRSNPSTELKDARSTDQINMRIGVGWGDSFVVSCSSLVSEVLCEVRCPRSNPSTELKDARSTDQINMRIGVAWGESFVVSCSSLVSEVQCEVRCPRSNPSTELKDARSTDQINMRIGVGWGESFVVSCSSLVSEVLCEVRWPRSNRSTELKDARSTDQINMRIGVGWGDSFVVSCSSLVSEVLCEVRCPRSNPITELKDARSTDQINMRIGVAWGESFVVSCSSLVSEVLCEVRWPRSNRSTELKDARSTDQINMRIGVGWGESFVVSCSSLVSEVLCEVRWPRSNPSTELKDARSTDQINMRIGVAWGESFVVSCSSLVSEVLCEVRWPRSNRSTELKDARSTDQINMRIGVGWGDSFVVSCSSLVSEVLCEVRCRRSNPSTELKDARSTDQINMRIGVGWGDSFVVSCSSLVSEVLCEVRWPRSNRSTELKDARSTDQINMRIGVAWGESFVVSCSSLVSEVQCEVRCPRSKASTELKDARSTDQINMRIGVAWGESVAHWLVRCCVSSMPAFKSSTELKDARSTDQINMRIGVGWGDSFVVSCSSLVSEVQCEVRCPRSNPSTELKDARSTDQINMRIGVGWGDSFVVSCSSLVSEVQCGVRCPRSNLSTELKDARSTDQINMRIDVGWGTSVGLWFILICNRMADDERICAFSSFLWLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKY2</accession>
    <name>A0AAV4UKY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_319511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013071">
        <property type="protein sequence ID" value="GIY58502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055470">
        <property type="entry name" value="DUF7042"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055471">
        <property type="entry name" value="DUF7043"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255:SF9">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23069">
        <property type="entry name" value="DUF7042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23070">
        <property type="entry name" value="DUF7043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7042" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7043" evidence="2">
        <location>
            <begin position="96"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY58502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="35265" checksum="3E635F662AE370F8" modified="2024-11-27" version="1" fragment="single">YGRRDPRTTWLENIDRKSYKQSFTDENAYRCFVFDYLTDKGVIQMSQSADATCDGLVSPWEGSRTMRLTKSKHPTSGCQFPSWVTAKHKWRTLDANSSTLVAYSSSGCKNGYICMKFFRRHNHIIEIQYGELARSTQEACYSTFSSTTQDFVTLVARTVPVSGCPQLVETNEIRVQVVKGASSSFKPELCGDHIVKIAGCRSYDSLEFLLAVRFACHGSWEEDGRNYLVTGLRNTGYKYCFVYWSKDKTAHLSGVHDTCRRKLEKTFTENVSFNISSTGVCDSFLSHQSASMPSLPTLIISLLLLALIPLSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UP28</accession>
    <name>A0AAV4UP28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_212171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013212">
        <property type="protein sequence ID" value="GIY59523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UP28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9264" checksum="B8F4777BD8320A17" modified="2024-11-27" version="1">MCYDESNGISNTIPISKMACCFASIDQQVSTSFYGKLMMNVVTLADFYPLLRTDDVLNEIKPTSFMSTIDLPGGYDQAGVDTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPH7</accession>
    <name>A0AAV4UPH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_661841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013223">
        <property type="protein sequence ID" value="GIY59626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8176" checksum="AA2FD70B14EB5963" modified="2024-11-27" version="1">MLPAFGIAMRKAWNICPPNGNVINDTERVKAWNICPPNDNAINDTERVKVCPAGERNFTQMRRSLNVFRVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQP9</accession>
    <name>A0AAV4UQP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Retrovirus-related Pol polyprotein from transposon TNT 1-94</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">POLX_2086</name>
        <name evidence="1" type="ORF">CEXT_89221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013310">
        <property type="protein sequence ID" value="GIY60322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF95">
        <property type="entry name" value="F-BOX PROTEIN YLR352W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="354" mass="40843" checksum="50AA7687B8DC936A" modified="2024-11-27" version="1">MCISLASLNISNCKNISDAGMVNLCNTNNEDSGFNSLKTLNIIQTAVTRQGVITLLRHLRSLHWLYYKDLSKILYNLHKSDFENNPIRYNLKYFEYNRERVALRKMLEVWAVMCPFVTRISIQDKITNVDLELCKRFQNLKKFKITSINYHPRGIIISPFISVKGAMLTELKVMYATVSVETIVKSCPNLKQLFLFNVTFEVFSLTDLNNGNYVLDNMASLTVKHFDFGRDLLAFDSIYLLIKSSKYLNELCIQYIEGFTDVLADIILELPYLSVVDLSFTDIKNSTLFRFLIREHITQMSVDGCPDVSLDDNSINKLISENQSGNTCSWVIDYSEMACESMWDYSMWSGEIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4USA9</accession>
    <name>A0AAV4USA9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">atg101</name>
        <name evidence="4" type="ORF">CEXT_507551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013352">
        <property type="protein sequence ID" value="GIY60631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4USA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY60631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25500" checksum="737A36868164A60A" modified="2024-11-27" version="1">MNTRYQMYEFSVEGRQVQEVVASVFHTLLFHRTLGKCHFKNEGNNYTVSTMNFEDVTCDFVDFTYVRCASEELNNYVSEEINSFCSALRSQDGPYSGQISLEFYQKKRQWFFTPETGSPWEVWTVKINVISLPNEHERQVYREKMGDVLAERIFEIVSAMNKYDYVPKIPDQASVNLFFDTSYHDVQPYLFKIEHKTSGPTNPSVGDAVRRLMKGTLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V715</accession>
    <name>A0AAV4V715_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_811231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013994">
        <property type="protein sequence ID" value="GIY65464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V715"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14711" checksum="33DCBF99D18D727A" modified="2024-11-27" version="1">MNIVLIFSVLHWSFCTIEKNEYSCSYFVYLPIFLDIIELFAHFFCTSLFLLAIGLRMMERHPELSEDFQSFCTIEKKIAAALHHSMVPIFRIRENLKIHIRSLIANARRKIFRRKFPCHKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V977</accession>
    <name>A0AAV4V977_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Corepressor interacting with RBPJ 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CIR1</name>
        <name evidence="4" type="ORF">CEXT_763051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014123">
        <property type="protein sequence ID" value="GIY66496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V977"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040014">
        <property type="entry name" value="CIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13151">
        <property type="entry name" value="CBF1 INTERACTING COREPRESSOR CIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13151:SF2">
        <property type="entry name" value="COREPRESSOR INTERACTING WITH RBPJ 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY66496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="472" mass="54823" checksum="F64A7CD15544D10D" modified="2024-11-27" version="1">MGKGYNNYMCKKPFHPGSKANIKRAWMAEQKTENEKKKQEELKVQYEKEQDLYNNRVLISSESKDKLELNFMYEAPPGAKKERQKEDDEPEYKFEWQRKYNAPREDYAKGNADIKDQPFGIPVRNVRCIKCHKWGHINTDKECPLYSQASTSSMPTTAMDPLELMKQMREDGYGLKENVLGHHLNPTAVNQQLIPSDESDPETEFLKSLSTAEKKKLLRKLKKLSKKQAKSKKKKSKKSHKSKGKESSESDSDDKKKKKKRKHKESSSSSSDTSSDESVTKSNRKHKKSSSKNDEDENQKKATKSKLHTKKESSDEQDEKLQESSKKDRSTNNPKSNQESSKREKHESKHDSNVFTKDKKSYHSSGSDAEEQNRTQVSSKHKADDNDCEYETTKRRKIDNNHFENDAHKSKSLSENKNNPDHPDGFSHIYPQAKIVANYIPSEEEYKGKIHDRFRHLNRDKRSPSVKQKYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBL5</accession>
    <name>A0AAV4VBL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Adhesive plaque matrix protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FP2_7</name>
        <name evidence="10" type="ORF">CEXT_322042</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014251">
        <property type="protein sequence ID" value="GIY67512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000095">
        <property type="entry name" value="Notch, isoform B"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000321">
        <property type="entry name" value="Protein delta homolog 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000255">
        <property type="entry name" value="Sushi, nidogen and EGF-like domains 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051022">
        <property type="entry name" value="Notch_Cell-Fate_Det"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049">
        <property type="entry name" value="CRUMBS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049:SF22">
        <property type="entry name" value="DROSOPHILA CRUMBS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043539964" evidence="8">
        <location>
            <begin position="24"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="779"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="242"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="277"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="349"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="443"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="480"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="515"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="653"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="739"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="759"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY67512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="814" mass="88799" checksum="FF69A5D02689C75C" modified="2024-11-27" version="1">MNSTVKVLLLIVCVLMYASIVRCASVSKNSIDENQTDIHSIPSNYQLAECKCTGGKCVFENGEESFASAHLNMVFSIKDLVKLVNAEKVPIALSHAVCVAGPCSTKPCQNGGTCTVDGQSFKCDCKPPFTGNTCEIGPCSSNPCQNEGTCAVEGQSFKCECKSPFSGKNCETECDCKNGKCRVTENNEVICECLPEYGKYDDVCTACDCGTGANCTFDVGFFSTEKYCLCPDGRKLKNQRCEDPCNNSPCKNGGTCKVEGKKFKCACKPPYLGDLCERDLCSENPCKNSGTCKISGTTFQCNCKQPYSGELCEKDPCTDNPCKNGGTCKREKIPSNALVGAPFYGDTCEKDPCTDNPCKNEGICMTEKNSFKCICRKPFYGETCEKDPCTIKPCKNGGTCTLDKDSFRYPCTIKPCKNGGTCALDKDSFRCNCRVPYFGDTCEKDPCSANPCKNGGTCNVDKNSFKCSCKTPYFGNNCDKDPCTVSPCRNGGTCKLFENSFKCDCKVPYTGNTCEKDPCSNNPCKNGGTCRRDKDSFMCDCQNPFYGKTCEEESVSITTSPTTKKTTISTTKMNSRSTSTATYTNLVFNITIPTAIISTKGINFTTYEPSNFTKDQNISTYEPSKFTDGVNSSTSMSSHPATVISSTKPTTKKPASCTKYGDCLNEGICKRTEDQENFCECLPHFGGTICEMFLPCVSLDQSCRAKGAVCKVAGMEAICECPPDKAFHQKSGMCEDICDSRKCAHGKCEIDGRNYKCNCDEGYIGTHCDKMVKKEHENFVPWFTVIASINLVMCLLLIGVLCLVCQIQRFIKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VC10</accession>
    <name>A0AAV4VC10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_72111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014236">
        <property type="protein sequence ID" value="GIY67409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VC10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="53" mass="5617" checksum="E07B4D0E4E1AF2A2" modified="2024-11-27" version="1" fragment="single">HIGCSPLCLSHNASYLCGLDILFQSSSHGVPLDPSNATSDVPVCWLNLQPPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHF8</accession>
    <name>A0AAV4VHF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinone oxidoreductase-like protein 2 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">v1g238856</name>
        <name evidence="2" type="ORF">CEXT_546851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014554">
        <property type="protein sequence ID" value="GIY69597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08241">
        <property type="entry name" value="QOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="18"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="336" mass="36908" checksum="7DD072AA56CA15A8" modified="2024-11-27" version="1">MEGDLKQLSHYKAAVLKKFDDKLEIVELPQTSKLKDTEIRIKVHKCAVNVADTLICSGKYDQEPKLPFVPGYEFSGEVLEIGSKVKNFSVGDKVIGLNKDTFSAMATECLSEERDLWKIPQDVAFDNAAALVDSYATVLIAARRANLREGDSVLVTVAAGGLGLAAVDLASNLFKAKVIGACDTEDKTSILREKGAFSTINYSKKDIYKSVMKETDNKGVKVIFDAVGGDTFKDCLQSISPEGCIVVLGFSSRKIPEILTSQLLPKSCALIGVSLTHYQKIINETYRSSVQEVIDMYLDEFIEPHVAEEFKLEDVNDAIQHVEERKSAGKVILDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VI50</accession>
    <name>A0AAV4VI50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_302041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014550">
        <property type="protein sequence ID" value="GIY69556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VI50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11804" checksum="09AED2EC1D81049E" modified="2024-11-27" version="1">MWANILTPKRNETDQQHQLFTFPIKCCSSFCHNCAIASTARRMKRTQYCPSLKSRGHFLPGSSSFWEGFISTTCMLCSAFACSWSPFCFRIDPDEHLNDDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKB8</accession>
    <name>A0AAV4VKB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_432831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014712">
        <property type="protein sequence ID" value="GIY70742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11956" checksum="37C2722253453411" modified="2024-11-27" version="1">MLTNSLTAVEDKQLCYPLESPSMLFEGLNTEIVNKSKQISRTNCHPRCSFRKALSAPERACFHQCLPWLRASRHHCVSSGPLEKSFHLYIPKHRLPLYRGYAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VS90</accession>
    <name>A0AAV4VS90_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_156795_1</name>
        <name evidence="3" type="ORF">CEXT_3381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015067">
        <property type="protein sequence ID" value="GIY73341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VS90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="104"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY73341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18451" checksum="A3EC9050C1EDB8F0" modified="2024-11-27" version="1">MDIGSAARHRVAIYFTQFYLKSGFTAADYAYYSRHLKEGVGRHNFGTIASDGEPTYLISNHQILVLTMNVRSLDNIHLRVQEHLMDVSGFNVTYEMILRNKTVRNDDCIYHHCSFTGNCYAASDFNKYKCECFAGYFGKECQYDGSCGPNSSSEVCRNGGTCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VU52</accession>
    <name>A0AAV4VU52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015095">
        <property type="protein sequence ID" value="GIY73528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VU52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14491" checksum="3CEBCDD79FD1EDA6" modified="2024-11-27" version="1">MMLSDKFPENLLRRRNSNYATHSLVSTSLNYCGFRCCASSLKLHFLTCSSVSLSEPVLLSGMLHFLSAPFHSCGLPGRTSVDRVHFCWISGGLEKCLWGRFNREFISFTHKLNLITSDVPSALSLNNQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVZ5</accession>
    <name>A0AAV4VVZ5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_746031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015222">
        <property type="protein sequence ID" value="GIY74457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="27022" checksum="8F7595FA19E421DC" modified="2024-11-27" version="1">MASFPRYLGEELLIKLMDYGERKWWSRSTDYPFIFFKDSELLRNCIAVKALVLLTVRRENMVLLGLWGKCIERGSWILKSGEGSRKLLVLNFLIRKQTHKNSRLVEKRQHEEIGEVFQADALHAGCCEGNFQYLYPFPSLCTPVLFVFGGEFFEASPSCLTGPIAQRKKKVFHLQNFTTLRRFPAATRETGSHLRFDFSGMLFYMPGTECFGVRGRQTSSVRLLPGLDFASLDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWD8</accession>
    <name>A0AAV4VWD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_668101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015235">
        <property type="protein sequence ID" value="GIY74606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12495" checksum="62A71B8C00C64D49" modified="2024-11-27" version="1">MTPYIGEATPVLKCLLGTSYAKRPFFSDKSPLSPYLSHLTTDSFATSSTKTPLWQKAGKISLQTIFKNVLGQNTNESDSSIRPSDGHHYPIIVITPKKRHSSSWWIPSECHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5P2</accession>
    <name>A0AAV4W5P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_72701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015664">
        <property type="protein sequence ID" value="GIY77708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="25055" checksum="76C2F00FF6556FB6" modified="2024-11-27" version="1">MHDIFCNSRVAKVNIRDEQVIMHYWKREREKKNNNNRKKRKRRFRNAGNKANILHKTQTSGDASATTEALNRRSIDGTFEFRTFVAFERRLTGSELVSPDSSSERKHVTSTFWQITVCLTKEENVSLKIFSFLIQEDKFEWKSCLEHSWCTVLKRILCEIIPCLFLRFGGEGEKNKEKARQFQESPPFRYRSHFLPVTQHHVMVYSSEKGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8I4</accession>
    <name>A0AAV4W8I4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein FAM214A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FAM214A</name>
        <name evidence="2" type="ORF">CEXT_249811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015768">
        <property type="protein sequence ID" value="GIY78538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8I4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033473">
        <property type="entry name" value="Atos-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051506">
        <property type="entry name" value="ATOS_Transcription_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199">
        <property type="entry name" value="GH03947P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199:SF11">
        <property type="entry name" value="PROTEIN ATOSSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13889">
        <property type="entry name" value="Chromosome_seg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atos-like C-terminal" evidence="1">
        <location>
            <begin position="58"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12777" checksum="E065D8B32817410E" modified="2024-11-27" version="1">MALQHCDEHTVKAAGKPYAPSDYHIPQERKEQFKWVKVEGIRSMTSDKVVNHFDSGLKSSKSGRIYLHTDIRLIIFRKSDLDAAAIHGQRSYELRTYTHGPMNPKFSPHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8V4</accession>
    <name>A0AAV4W8V4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_145661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015853">
        <property type="protein sequence ID" value="GIY79162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8V4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10933" checksum="8EAA53E0A6FB3E1E" modified="2024-11-27" version="1">MESFRSEENHQFTKDAFLITLFDMRNQSGRVVSPLLNNKGEKEQPPSKSGKGCNLGMDDQTIILDGSMLDAPRYAFQEPKRSSKRMLNAKCYSSGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WC08</accession>
    <name>A0AAV4WC08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_763741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015928">
        <property type="protein sequence ID" value="GIY79768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WC08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13600" checksum="D137AA2290AF1EB8" modified="2024-11-27" version="1">MIECPFPFMAKVPSLLIFSPEIFKHLEESIELMGHPSLLPDHTSQNMYVDQRSEELGKLGLVLLSQYLQKVPETGHGMMDYEEDGDVAINLSKTRRKTAGDTPNGNAEPEDGEPQGQICKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEU7</accession>
    <name>A0AAV4WEU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_65061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016114">
        <property type="protein sequence ID" value="GIY81381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8323" checksum="357F87BE2D581DA0" modified="2024-11-27" version="1">MDNWERRKKKRWMASEKKNSSILSLKLGDFLRVQKSVEIPGDSGSMDPWRRRPKNAPRYLVTGLLMPRHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WNQ2</accession>
    <name>A0AAV4WNQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_717101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016530">
        <property type="protein sequence ID" value="GIY84550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WNQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9980" checksum="C2D68BC77C01F538" modified="2024-11-27" version="1">MGRNTCRNFYFGCSYGDFRGNVHFDCCVWICLFSDVVRKENLISIMSNAGRSCCDNCWDGVLVGKRKVLFWSDDLEHFSRKTFKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WS00</accession>
    <name>A0AAV4WS00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_454171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016548">
        <property type="protein sequence ID" value="GIY84710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WS00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9971" checksum="5FE1F9307A2EB951" modified="2024-11-27" version="1">MIAYVHDFVNIFNYLVTNRRTLHSRYISTLFKSYQSPHAPLSGKDSTTECEFMTQNATLMPLTTLNDTKKTPSCQRDCYIRDPGTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAF0</accession>
    <name>A0AAV4XAF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_254851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017490">
        <property type="protein sequence ID" value="GIY92065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11556" checksum="3FA1044E3578B1B9" modified="2024-11-27" version="1">MSQVRFLPTGTPSRTTPSRVLHVLTTGHCGFVYKSLPAGDSSYKSLPAADSSYKSLPAADSSYQILACSGFVLQIPCLQRIRLTNHLPAADSSYKSLPAADSSYKSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBB5</accession>
    <name>A0AAV4XBB5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Immunoglobulin I-set domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_169441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017532">
        <property type="protein sequence ID" value="GIY92395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Immunoglobulin I-set" evidence="1">
        <location>
            <begin position="38"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16098" checksum="157FA99AA24B9134" modified="2024-11-27" version="1">MIYAKDVKKSDKGIYKLILRNCFEQAEATFTLKVRSAPKILDCPAEIFCLEGASVRFKVGSKSIGSCSLQLFKNKQCITDNRITFENFDNVIILCVKKVCKADRGKYEIVVKNNLGQSKAEFSFKVIVPQYVLRDFLRRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDQ9</accession>
    <name>A0AAV4XDQ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_190386_1</name>
        <name evidence="4" type="ORF">CEXT_500621</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000165">
        <property type="protein sequence ID" value="GIY92588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="39"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY92588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10447" checksum="86E11EA8305FB3A2" modified="2024-11-27" version="1">MSKASSSRCQALAELGKEIIPWKMVETEPKLFLIQGDVYEVEKLVALKIVKGQKLYRVRWRGYGRESDTMEPEENLLSCKEMILDLEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFF1</accession>
    <name>A0AAV4XFF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017545">
        <property type="protein sequence ID" value="GIY92509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10291" checksum="5E21F0A0573A665E" modified="2024-11-27" version="1">MDCNPQLFCYRNLVWRSTEEKSWFRGIDAIAEEHHLPVKIYVPLQKNIWAQEKDGRKKQSCVGRGTRKCLICKRKKKEEKKIWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFL6</accession>
    <name>A0AAV4XFL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_92661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000192">
        <property type="protein sequence ID" value="GIY92746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9124" checksum="A4D80B9AC003EB50" modified="2024-11-27" version="1">MSRAILHAQSTPNNCTDKVAAVLFFSFECLQRESLVGRFIPEKLLKIDNCCYPLFSFSLVFCRSAFLTSQSLPFSVKVVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKE7</accession>
    <name>A0AAV4XKE7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_180561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000367">
        <property type="protein sequence ID" value="GIY94218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10728" checksum="4F2E1F728C8833F4" modified="2024-11-27" version="1">MSFNQEMENAPFLETKSLIITFAENLNHKYEIASLPCSGILCGDLRCPGRGSTWTPACCQIRTTSDHPETWKPGGTGCVKRCKICERHTDSIAGKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQY7</accession>
    <name>A0AAV4XQY7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_541451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018065">
        <property type="protein sequence ID" value="GIY96590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9742" checksum="4A41FE8A05B21C9C" modified="2024-11-27" version="1">MDWPAQSPDLNPIEKTLGRCIAEFRHYPSIIGEGTSMSSPSRVEENTTSCHTRTCGKYAQSPDLNPIEKPWDALHRRIQALPVHNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSN5</accession>
    <name>A0AAV4XSN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_478181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000727">
        <property type="protein sequence ID" value="GIY97006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14268" checksum="4E0875C122A96C7C" modified="2024-11-27" version="1">MLSNGNHCKRPKTRIPRTPHDWKPFWCVNTHWATLKLDGPSDHHCLSTVSPAKWLLTLPRVVPPLPLQMRTWLISSEGVVRTVQGQRERERKRISRSSPPKKRNYDGRQNLAGCGTPDATELRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU73</accession>
    <name>A0AAV4XU73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_778931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018163">
        <property type="protein sequence ID" value="GIY97484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13157" checksum="D7AA244EEDA9D716" modified="2024-11-27" version="1">MLRKWIRMFNEGRKISTKRNAMEESVQCINENRSKTEAHGSNFRVLQRYATDGNDYLKNFQNKTWICNKTPETKLQSLEKRHTSSPKSKKEKPPLSSRKSCAPSYGLSKIFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUU5</accession>
    <name>A0AAV4XUU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_227031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018234">
        <property type="protein sequence ID" value="GIY97955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="9033" checksum="FD1525252ACE3FE5" modified="2024-11-27" version="1">MPPNRQQEQKDNHAKTVVDILNNCGVYRKSIVFSCTKKVIRKMQFFGKAQTEARWKLENKMVAHTIKWKQMVLRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYD7</accession>
    <name>A0AAV4XYD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_490531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018343">
        <property type="protein sequence ID" value="GIY98835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14408" checksum="68A8D69838F65B50" modified="2024-11-27" version="1">MFIHLRNSHINRQVAEDIKVNVHINRKGAQEIKLNVYINRQVVHKTKVSVDIIAKLLKLSKLVCILIARLFKKPNESVKCYFLTYTYEVLIPAISIAPSIKKYIISIANLLKKSVSRSSKFECSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZD2</accession>
    <name>A0AAV4XZD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_449951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001002">
        <property type="protein sequence ID" value="GIY99090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="12862" checksum="EF619887AE8620CD" modified="2024-11-27" version="1">MNAIRGFPLATGTRIGKRSLIECSGAKPVAKMSFREECLLWRCSFQMAVVECGYSMEGIPGDAGCANLPVANDFIGGSLLGGPGRPRRSPWTSSNSTKDAHSAGQNPEHVPGHRIQPYFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1T8</accession>
    <name>A0AAV4Y1T8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_441911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001275">
        <property type="protein sequence ID" value="GIZ01272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1T8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11294" checksum="C8681EB282580401" modified="2024-11-27" version="1">MDWSCLALNTLACQTKHAWLTNQSIRKRDEMRVCDPQEGVRSKLQCTVLINLKIYRQNNLVVLYFDDLGILELNWIPQRSSLSIQSPPRGIKGKLPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4M8</accession>
    <name>A0AAV4Y4M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_167541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018750">
        <property type="protein sequence ID" value="GIZ02018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11836" checksum="BA54259F69A72F01" modified="2024-11-27" version="1">MLEVKYFFETVLPAREERDYVLHFFGRLLDGHRDEKQFLVLTDKRDGNNGKTTFINLMECVFSSYAVCKGSKAVCEQSRESINSHDTGLARFKVFVCSLWTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6T6</accession>
    <name>A0AAV4Y6T6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mediator of RNA polymerase II transcription subunit 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">skd_3</name>
        <name evidence="2" type="ORF">CEXT_51811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018884">
        <property type="protein sequence ID" value="GIZ02982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6T6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="19265" checksum="C62026D0CC2A7B55" modified="2024-11-27" version="1">MNSLKIPTSTSSSSPVVSISSPSVSVDSPSSSANGISSASATRKNEKSDKLKQLTHYRTSIPFHKRSAYSDSAEMDTFSTSSTFTAVSMPGSSLPNSVNTNFQFKGLNQSLRSSTPSGLPQLHTSVVQPSSPLPDTPMTDGTNSQSAELAMPTLSPHPPAIKEEEDDEEMPQESQDQKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y966</accession>
    <name>A0AAV4Y966_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_308491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001605">
        <property type="protein sequence ID" value="GIZ03454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y966"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10831" checksum="108515AC066DD241" modified="2024-11-27" version="1">MVLNPSYYKKNILHLIFTEEIQYLDLDSFKKETASDETPVPILAADEDEPIIPETPLVEYLDTIKPRLLRSKTDLRSISELNRVQTFYLWMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB83</accession>
    <name>A0AAV4YB83_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transposase IS30-like HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_16422_1</name>
        <name evidence="3" type="ORF">CEXT_471351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018955">
        <property type="protein sequence ID" value="GIZ03475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase IS30-like HTH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ03475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14652" checksum="737E3B3E6A90221D" modified="2024-11-27" version="1">MDLKGKEITPEERKIIVKLRNEGKTLRKIGKIVGRTHPSIQRVINNYTSSKSIISKPRSGRPSKLTVREKRYVFKSLRLKPRISAFQITNDVRERFKKTLHEDTIRKFLKRLGIAVLLAGSHTYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBQ9</accession>
    <name>A0AAV4YBQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_481491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001633">
        <property type="protein sequence ID" value="GIZ03640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10846" checksum="82DA3543E4CE27D0" modified="2024-11-27" version="1">MPSEKSIPFFLHAFKFDSLVQNIVRPFPTKVKRSWVFGRVEGLPKVPKPRTPPSQAAVTARREFVAKKVTQGVSSMVQGTPPTPSPVSATENHYLSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD73</accession>
    <name>A0AAV4YD73_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Inx2</name>
        <name evidence="12" type="synonym">inx</name>
        <name evidence="13" type="ORF">CEXT_437891</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019220">
        <property type="protein sequence ID" value="GIZ05142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIZ05142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="36807" checksum="B296D036DD04B9F9" modified="2024-11-27" version="1">MIELKLVKPSIQGNGLNFLVEYITVTAVRNQTRLLAFCSHKNESVPCIPEDDIPPKVLEAFSLVYSTCAQHSAFKIEDGKQNYTESKYHLKENIFNDVVGRLSLLFLFQAVIFFLPRYFWKSVESGRLERLLSFLHNTSYRPMDNIVRMVNDVLVNSERNKYYLTQYFTAEIFNVIASILCIGIVEFCLGGVHQSQSVDVIEFADKNFLPCWFLHCNSSRNILPKFDKCTIHRYISLENIKSHEAMLIMPTSIIYGKIYIFLWWWFLMMTVMFSTGLQNTYPRFTSFAIYSFGYELRRYKYRGSENYNKSFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M695</accession>
    <name>A0AAV4M695_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_772971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001889">
        <property type="protein sequence ID" value="GIX67592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M695"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9584" checksum="ADFA831A2AB3DDA9" modified="2024-11-27" version="1">MKGKQHGLFAPLIEIQPGILFSQLPPAAYQGFFSNCLPRSILFPPTPNNSNVVGGGREGRSKLNSSRVSENMYGSVTSSSKSSLEQTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6F8</accession>
    <name>A0AAV4M6F8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_319551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019397">
        <property type="protein sequence ID" value="GIX67410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6F8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13204" checksum="427A861A9EF2E879" modified="2024-11-27" version="1">MEHYYTGKIIKTHSLNPRVSHKVILINCISADSQTMHCLYGSGRSLMDKCFQKAQRITKITRKSCSRQRMVNATSKRLQTLFVPRNNSQRKTIAGRQNEEIKYLRSKEMPPYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M821</accession>
    <name>A0AAV4M821_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_536181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001979">
        <property type="protein sequence ID" value="GIX68602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M821"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7667" checksum="FA1DF13DFF8B96E9" modified="2024-11-27" version="1">MSTSRVGIPLNHSPGPISDVELFCVVLSIASPSFTLASLDADTGSDEIQVQLQDMTFTPATGTDYYSPGNSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9T0</accession>
    <name>A0AAV4M9T0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_196371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002017">
        <property type="protein sequence ID" value="GIX69098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9T0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7273" checksum="5EF20B277EED364B" modified="2024-11-27" version="1">MTAPYFIDLSEDKPHGGLPRWGGNALANRLHSGVAPSGHASPAKPGQWESSVGLGFQENAKDKIRSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MA87</accession>
    <name>A0AAV4MA87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_315171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019527">
        <property type="protein sequence ID" value="GIX68808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MA87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9583" checksum="BB52BEB4009B942F" modified="2024-11-27" version="1">MKSRSETFHSSPLFYFGCFYRQVSSLLGDDIPALHKLSHLLAIHHTGMTSRHAAKALHRSAAEISGEKLELFSCTRVNNVKQKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFS0</accession>
    <name>A0AAV4MFS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_297351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019701">
        <property type="protein sequence ID" value="GIX70881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="11771" checksum="17EBD72FD1A13FB6" modified="2024-11-27" version="1">MKPCIDSSQSNSCWLFSVNNSGRTCIGDAALCTYTCGARALSGCHLGAIPTHTPRTQWGKSEWPSTVQFGGTVQGCPREGGPLSRIEQGLNERSLQICPFLAKSTHESTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHV4</accession>
    <name>A0AAV4MHV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_190631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019753">
        <property type="protein sequence ID" value="GIX71445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9268" checksum="B4889509817B672E" modified="2024-11-27" version="1">MEGDSYSSRCDHEIMSLLPPPTQLCPELLNSQHLQNVNEPTVVEDGRLQRGLDVRGFDIGRSLGWFCMQIMHQMPSQRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMZ4</accession>
    <name>A0AAV4MMZ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Caveolin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cav1</name>
        <name evidence="7" type="ORF">CEXT_359761</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cell membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Caveola</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the caveolin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019982">
        <property type="protein sequence ID" value="GIX73738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005901">
        <property type="term" value="C:caveola"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070836">
        <property type="term" value="P:caveola assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001612">
        <property type="entry name" value="Caveolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10844">
        <property type="entry name" value="CAVEOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10844:SF19">
        <property type="entry name" value="CAVEOLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01146">
        <property type="entry name" value="Caveolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX73738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21582" checksum="018B3964960B5DBA" modified="2024-11-27" version="1">MFRFSGESRVEVKRSLGFKRHYLFDVKRTIFGAYCLSKLRGMYIFRRHIFPEFERKCISLKENGWSNAFSMVEFDDVIAEPEGTYSVDCVWKSSNRLFTCSKNCCYKTLTLICGLPIAFISGCSFACLSFQHIWCISPALRQCRINCHMVRQYFTTVLDSCLGPCCSEMGLCLSRIRIEDTSSLPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPE6</accession>
    <name>A0AAV4MPE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_42719_1</name>
        <name evidence="1" type="ORF">CEXT_664822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020067">
        <property type="protein sequence ID" value="GIX74422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="28067" checksum="87B4AEFF2FDCD14E" modified="2024-11-27" version="1">MMTNLMKTLKEYSMSRLDCLAQLGYGGVNSTKLCFMYLDYYRVEQCQKYFYDYVLCIRNGSLNEYLFKKVHDCFRELWCLCSKPAVDLLIRVLVVAVVGYHPAYPNLGVLLPRNDSATVSYDYYYNGENFLDQDVNYDWREWKPINEERGLRQLFIVIGLRQSIVCRGDMIEEWSGVIRSCMHSKRHNASDFERLLKSLVFCIKKTPLTKCHFEKYSVFELAVDYMLKLFKIQLQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSF9</accession>
    <name>A0AAV4MSF9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_313921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020093">
        <property type="protein sequence ID" value="GIX74763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043876087" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9725" checksum="D353B334621D4568" modified="2024-11-27" version="1">MKASTTSKVGRLVSFRLVVVLLSLTRLVDARVWNPGISLANDSRGKWVKERDRNAVADMSGFNAGALLEMRMCRAVVPVHRTRQMVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MU45</accession>
    <name>A0AAV4MU45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020209">
        <property type="protein sequence ID" value="GIX75913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MU45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15506" checksum="5DFBA030F7F0034B" modified="2024-11-27" version="1">MEGICNHLLPCFELHILCPESLVANWIACVVYATLTLYSTVILGKLECSLINCIPASLTLYSTVILKTGIPFDNIKTICYKQQKSRIAKIEIMNYNKAGTFSAKHPFSERRLTVSIQPGVPCNAVFGLETETKQTTSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXR1</accession>
    <name>A0AAV4MXR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytoplasmic dynein 1 heavy chain 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dync1h1</name>
        <name evidence="3" type="ORF">CEXT_808081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020310">
        <property type="protein sequence ID" value="GIX77260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.130:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF13">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="303"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX77260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="720" mass="82665" checksum="DEB322209348FAC9" modified="2024-11-27" version="1">MEKVLQLFQISQLNHGTEGVAHVIDPKAISKEALYGTLDPNTREWTDGLFTHVLRKIIDNVRGEISKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPLIRNFIQEKKEDTLKEDLLSPTLQVQRDVANILSPHFTSDGLVVRALDYASSQEHVMDFTRLRALGSLFSMLNQSCRNVLNYNHSHPDFPMQQDQLDRYIPRCLIYALLWSFAGDGKLKIRSDLGDFIRGITTIPLPPQTGAPIIDFEVSVSGEWSPWQGKVPQIEVETHKVAAPDVVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRSLPDMEVVGLNFSSATTPELLLKTFDHYCEYKRTPNGIVLSPIQLGKWLVLFCDEINLPDMDKYGTQRVISFLRQIVEHGGFYRTVDQAFVKLERIQFVGACNPPTDPGRKPLFPQNNINTLYDPNFFFIRFLRHVPVVYVDYPGETSLKQIYGTFNRAMLRLLPALRTYSDPLTAAMVEFYLMSQERFTQDMQPHYVYSPRELTRWVRGICEAIRPLETLPVEGLVRLWAHEGLRLFQDRLVGEDERVWTDENINIVALKHFPNINRDTALERPILYSNWLSKDYLPVERQSLRDYTKARLKIFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVFQIKVHNKYSASDFDEDLRSVLRRSGCKVCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZD6</accession>
    <name>A0AAV4MZD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_265601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002800">
        <property type="protein sequence ID" value="GIX77902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19390" checksum="FEFFC93F56B05BD8" modified="2024-11-27" version="1">MAIPSARGRGRLADLSHSMVIVYHNGCPIPSQSDFLSKPFQLNQCAINNLRAQDSIGAVWRNPRRHKSDRPCSPVDYRRDSLPRFYDAGFRTWRGFATTPATLLREGQFRTLVPFHRDPLFSNKQSGISNERQNLWKRFDGPRIGSHCSSRQHTSWSKTLTYPFVIMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5I6</accession>
    <name>A0AAV4N5I6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_660111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020514">
        <property type="protein sequence ID" value="GIX79609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5I6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="42" mass="4662" checksum="3E71BE5C8AFA1F93" modified="2024-11-27" version="1" fragment="single">FDFWRDVEALPAICQDAPPADGTVGLNNVFKNVKQDVEVTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBM0</accession>
    <name>A0AAV4NBM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_413741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003215">
        <property type="protein sequence ID" value="GIX82207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="31483" checksum="E254205E9F5B6667" modified="2024-11-27" version="1">MECVNLLGQGRPDSQIQLALARVAVSFLSNMECVNLLGQGRPVSQIQLATARVAVSFLSNMECVNLLGQGRPVSQIQLATARVAVSFLSNMECVNLLGQGRPVSQIQLATARVAVSFLSNMECVNLLGQGRPVSQIQLATARVAVSFLSNMECVNLLGQGRPVSQIQLAKPGWLSPSYQIWNASTFLARVGRLAKYNWLQPGCLSPSYQIWNALTFLARVGRLAKYNWLQPGWLSPSYQIWNASTFLARVGLLAKYHWLQPGCLSPSNQIWNASTFLANVGRIAKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHU9</accession>
    <name>A0AAV4NHU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Zinc finger protein 214</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ZNF214_3</name>
        <name evidence="15" type="ORF">CEXT_663031</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in transcriptional regulation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003327">
        <property type="protein sequence ID" value="GIX83375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:003126">
        <property type="entry name" value="Zinc finger imprinted 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000016">
        <property type="entry name" value="zinc finger protein 37 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001134">
        <property type="entry name" value="Zinc finger protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF178">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="114"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="381"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX83375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="424" mass="47058" checksum="22C29602607C70D7" modified="2024-11-27" version="1">MASTPEQVVCTPTFVFPTPFAVNSFQLWKDDQKDVLTLCNSAAGGWPDYRGFDPRLTNFQLAAASQSQQLQHPEDSSKSKGGTRGIKNHISNQNDYIPQRNLLVASAPPAFPGIEAGLKIPNPNLDKQTQQQPQPPQPPPPQQQQQQQQQQQQQQHQQQNQPQHHHPTHEDNSLVSDKDQRSWPCPSCKVPFKQASELQAHLSAHTKGEKTVPCDICGKYFASGDRVRIHVKAAHGEKSCSCEICGSGFSYRCKLLDHMRTHTGDKPFHCEVCGKSFSQKNHLTRHSMIHTGERPYPCDFCGRGFYRKDKLTRHRRIHTGERVTGQPRRRGGGQFNAKMPTVRHGRGMAHHVGTSSQSNAVANSASASASNIKMESAMPEPIASTTTSTNLSFAPPTLTPTISPSHYRAPPYKPDWQTPPSGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIB6</accession>
    <name>A0AAV4NIB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Antizyme inhibitor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">azin2</name>
        <name evidence="4" type="ORF">CEXT_427321</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020870">
        <property type="protein sequence ID" value="GIX83471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 C-terminal" evidence="3">
        <location>
            <begin position="94"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX83471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="262" mass="30019" checksum="984E5AE8E2383461" modified="2024-11-27" version="1">MLENLFVGLEEEDTNLDVESYETFVLKTMNAKSFPKNINRETRVQVHHYGHRGRIFWINRKRRIFFYKLTQEIQNSLKNNFPDGDVEFIAEPGCYCVASAVSLVTTILGKKSISTNEKSDIKKEYFLNDSFYGSFFEHHDIYHVKPVPVLAASEMKQRPKYKSRVWGQTCCSEDIVEDECVLPDMEDGELIQWPNMGAYGKGVSSTFTIVPSPADRYVFIQNSKLKLDSIPNAEKAIDYIAEKADLVQHAEEVNGNGLIKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJP3</accession>
    <name>A0AAV4NJP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_353991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003461">
        <property type="protein sequence ID" value="GIX84898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11362" checksum="7E03CE97ED551FC7" modified="2024-11-27" version="1">MQLYSLPAFIENTYSTPHCEELIRIMPFNKSTFQTDFPLHPEAAIFKEATKIPVHIPLCSLRNRAPLCILIKSTRDSNFQWGFQIDILNRIEKRSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NP56</accession>
    <name>A0AAV4NP56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_96911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021144">
        <property type="protein sequence ID" value="GIX86473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NP56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17312" checksum="47A237648E38501C" modified="2024-11-27" version="1">MKRNGQRWLKFPFPINVKANYSDRASDYAMMGKKILPRIDAVCVAAIPYTPIPSHVHGSNFYSLYHVTTPTFSSIYHYPHDVWPVFGAGKGSPGLKIERETSFNCMCVLTNLGRRVGSIREDLFVGTFGNSNYSSLSREKQAFTRQNFPPGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0S1</accession>
    <name>A0AAV4P0S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Amphiphysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Amph</name>
        <name evidence="12" type="ORF">CEXT_586771</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003961">
        <property type="protein sequence ID" value="GIX90654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11790">
        <property type="entry name" value="SH3_Amphiphysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000013">
        <property type="entry name" value="Amphiphysin isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000172">
        <property type="entry name" value="Amphiphysin, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003005">
        <property type="entry name" value="Amphiphysin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46514">
        <property type="entry name" value="AMPHIPHYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46514:SF3">
        <property type="entry name" value="AMPHIPHYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01251">
        <property type="entry name" value="AMPHIPHYSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="11">
        <location>
            <begin position="22"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="10">
        <location>
            <begin position="357"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="296"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="143"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX90654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="419" mass="48175" checksum="A9C74466CCB0AC92" modified="2024-11-27" version="1">MSELNPFSRVLQKHAGRAKERLLQNLGKADRTTDEDFDLHVKNFSKQQNAVMRLHKEFKNYYMCIRAMQAARRSLMDTVCELYEPCWDGVEQFLFKTEVSNKNFDDFCDKINCELVAPVGTYLCQFPEFTNKISKRNRKLLDYDNSRHNLQNLETMKKREETKIAKAKEQLEEARNHFEVINSELHEELPALYDSRVSFFATHLRNLFQSEAGFHKQDAALFIDINGILEKLNDAYKKGSLMAKSKICLESMENGAESKLPDPDYFLSKDNNSSDNEIKIESEKLEECKIEEKKVEESKVQEDGSSVSTNESIAFSTPPTTTERNMNLEMLSEMSIVDEDVKSENKIKGEASPSGFNVLYQVQGTYKYAAEDSDELSFNVGDIIDVVEYDDPEEQEEGWLMGVFNGKKGLFPANFTSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P349</accession>
    <name>A0AAV4P349_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_574601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003959">
        <property type="protein sequence ID" value="GIX90636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P349"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="23684" checksum="120E49E65F144B71" modified="2024-11-27" version="1">MIGPLSVDNARDHSSQFSFVHLSHIRIPPVPLCSIKAAIFYKENFPLLRPKKEQPTLLQEKHPSGSWTIEDRSAIRNITKFIVSESCTYNGHRHWDSSLTSVRTERAGYRDTALMFRMFLNGTGRSLGKSSPRTPNRESIDSHPDNGIFPTTVMSESEENGSQGGELPKMGPDRGQRSRDSGSESGNSSYGNGGFRARESTRTIRSWGLRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P483</accession>
    <name>A0AAV4P483_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_111507_1</name>
        <name evidence="1" type="ORF">CEXT_350141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004086">
        <property type="protein sequence ID" value="GIX92032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P483"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053231">
        <property type="entry name" value="GPCR_LN-TM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902:SF4">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902">
        <property type="entry name" value="LATROPHILIN RECEPTOR-LIKE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="49044" checksum="6801CFF99F325464" modified="2024-11-27" version="1">MKSLSFIFTLSPSDNLSNSSFFRISSAESRRINQGYYEEVRTLGGSCFPRDTCAFLNNSTEDHLWGDRTCECGDHCVRHGTCCVDSRYSGIEYRSSNHLQESCQKVQNNIITVTMVSQCPSAWQKSYVNGRCISPEGRLEDPLSTVPVTSLTTRTTYRNYFCALCNDDANSILMWDIEAKLSLVDDTSNSVGASVELMERLEYNVEKGSWGVQYVDAETNDQQFRKIKLKFALPTGLKKMVKQCHPRIVSDCSSSLRSSSLRQRCLAYYSPIRARKDGSSVFVDYRNIHCALCNGFRVRPNNVACPKIRSIKKDRPSPDPRRAVRYQHRGRRQRLQGRPSPRPLLQEVQVTGVCHAELRHQKRCLRQIRVNGCKILILYNLQVIPSEEYSPEENHTKVNNLKGCIPFYFAYVYWTSHVSKVNISFNLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6J7</accession>
    <name>A0AAV4P6J7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_696651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004144">
        <property type="protein sequence ID" value="GIX92664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6J7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10546" checksum="F09DEE6EF55F8B7C" modified="2024-11-27" version="1">MGKGEEKQNLDLFVLSEDKKSEAFQIAAICYLKTKSESLSLAKEEIGLHGHSCWEKPISLSRKMGHGPTSEDTKDFQFWVESKTFLAVKCHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PER7</accession>
    <name>A0AAV4PER7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_724171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004347">
        <property type="protein sequence ID" value="GIX94211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PER7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14745" checksum="24F72EF37C6C349F" modified="2024-11-27" version="1">MRTISLGVIVPVYPTSSTSSFKWPTTVGGEYWCVKVCVHSGEDKRNQISSAARLCPRPLTRPLCSHAHWLCYPLCDYRNWLHELPLKAQRDSVDGECSNTHFRSGVPPNNFQFPFEQKIIACSTAAIAFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PIT4</accession>
    <name>A0AAV4PIT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Brain-specific homeobox protein homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BSX</name>
        <name evidence="5" type="ORF">CEXT_134081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004570">
        <property type="protein sequence ID" value="GIX95885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PIT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050848">
        <property type="entry name" value="Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333">
        <property type="entry name" value="HOMEO BOX HB9 LIKE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333:SF8">
        <property type="entry name" value="HOMEOBOX PROTEIN CEH-62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="2">
        <location>
            <begin position="30"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX95885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12177" checksum="ABE11C2643E2E99C" modified="2024-11-27" version="1">MLQDVLKNLPHGLPFPGALFPSEGGKPCRRRKARTVFSDQQLHGLEKRFEAQRYLSTPERLELATALSLSETQVSTTPIIISYISHEVYDFLSTGNIRNTQNTLMSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q097</accession>
    <name>A0AAV4Q097_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_575271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005369">
        <property type="protein sequence ID" value="GIY01797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q097"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10540" checksum="778F14711F378F45" modified="2024-11-27" version="1">MSMVNMAVEDSKFRSSYLLVLLQSQVSSVGSSAAGMLTSSSVRPFHLPFESLGVQSDWSMRLTDGIRLQTPSGAFERKLFTIMCQSVEGERQFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4I9</accession>
    <name>A0AAV4Q4I9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_197931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005685">
        <property type="protein sequence ID" value="GIY04207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="282" mass="32274" checksum="ECD22C9BE8598FE7" modified="2024-11-27" version="1">MSKSKSGGVMNVEYVAKKEPEVLVAPCQGWSDPCEFCDKRFGNWLEANEETIAKIPAKPGIFTVGLKHKNSVELVDITIDKNDIQKLAYDRIDHAKERVADKKSKVTKSVVMCRWMTFKISDDKEVASLCAHWYNNGVLPKFLNAWPGSDILGKTDKFMFSEELQKWCYPKKDAFWRKPKAMPSKLVEVVESCNWFKACDVCDRYFSEWLKLDDVVANELAPNTTGIYMIAVLYGKEREVVNIYYGQNDIKVNIKESLENYSKSMSYVLRNKSSSIKVLASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6G9</accession>
    <name>A0AAV4Q6G9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_203581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005678">
        <property type="protein sequence ID" value="GIY04169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6G9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15455" checksum="EFF87A23CDC2745F" modified="2024-11-27" version="1">MQILFEQPMFPGRITWRQTSNGARAANGKVDKSTKGKGMICIFSSFPGWGLKYAGGRKLSLWERKEKNNIYTKLKRNECRSFSEQPMFPGRIHGGKQVMDPELSMAKLTEALKEKDRFAFSVPSSGWGLKYAGEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCW7</accession>
    <name>A0AAV4QCW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006081">
        <property type="protein sequence ID" value="GIY07275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9078" checksum="07DC3DD537C32111" modified="2024-11-27" version="1">MNETIIICCERGLRSRSRTPLRSLEELETNYHTLAHTQTNRSNFWFTRHTIHQNRHDGLANHAAECKLSCTVIVSLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDH1</accession>
    <name>A0AAV4QDH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005948">
        <property type="protein sequence ID" value="GIY06339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10781" checksum="77D3F4023EAF5D2D" modified="2024-11-27" version="1">MEQARALELAEMHSASFPSSSNPSPVSTVKEGYIIENKTFASDPGKLVPLMNLPVPQTMVSLKRAMEMIAHYCHWIRKFSERIRSYPSKIPFPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWL7</accession>
    <name>A0AAV4QWL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_722351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006826">
        <property type="protein sequence ID" value="GIY12669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7690" checksum="11D55D19A86BD9A4" modified="2024-11-27" version="1">MEERSPPAPAAIANHPVGYRIPHSRADDIRLKHETPDFCWCEVLAEDLPLLCSRLLSPDSPQTLVLWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXX4</accession>
    <name>A0AAV4QXX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein unc-13 homolog A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Unc13a</name>
        <name evidence="2" type="ORF">CEXT_392681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006871">
        <property type="protein sequence ID" value="GIY12962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031594">
        <property type="term" value="C:neuromuscular junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098831">
        <property type="term" value="C:presynaptic active zone cytoplasmic component"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042734">
        <property type="term" value="C:presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030672">
        <property type="term" value="C:synaptic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043195">
        <property type="term" value="C:terminal bouton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019992">
        <property type="term" value="F:diacylglycerol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017075">
        <property type="term" value="F:syntaxin-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061789">
        <property type="term" value="P:dense core granule priming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099525">
        <property type="term" value="P:presynaptic dense core vesicle exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035249">
        <property type="term" value="P:synaptic transmission, glutamatergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016081">
        <property type="term" value="P:synaptic vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016082">
        <property type="term" value="P:synaptic vesicle priming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010439">
        <property type="entry name" value="MUN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027080">
        <property type="entry name" value="Unc-13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10480">
        <property type="entry name" value="PROTEIN UNC-13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10480:SF12">
        <property type="entry name" value="UNC-13, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06292">
        <property type="entry name" value="MUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MUN" evidence="1">
        <location>
            <begin position="45"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10688" checksum="CE7A2D43FA6CDA53" modified="2024-11-27" version="1">MYRNNFPASSPEKLQDLKSTVDLLTSITFFRMKVQELSSPPRASTVVKDCVKACLRSTFQFLYDNCLDLYGREFQVEPQEKTREGGTRSSELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3A5</accession>
    <name>A0AAV4R3A5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_659791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007372">
        <property type="protein sequence ID" value="GIY16408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3A5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="19081" checksum="CB198654EB2CD49A" modified="2024-11-27" version="1">MSGSLVKSIIKENQYEDSLKSNSKEIAGEKNIKSSRTDRKIRNANFENRKMSNRMLPKHINDRGNQISFSSLIALNSPAINSYAANSSAINSYAANSSVINSPAINSYAANSSVINSPAINSYAANSSVINSPAIDTYAANSSVINSTAINSYAANSSVINSQPLIPTLLILQSLIPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R412</accession>
    <name>A0AAV4R412_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_233084_1</name>
        <name evidence="2" type="ORF">CEXT_608591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007357">
        <property type="protein sequence ID" value="GIY16309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R412"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.900.10">
        <property type="entry name" value="TCF3-CBD (Catenin binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027397">
        <property type="entry name" value="Catenin-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="22310" checksum="9A96AAEE02D9E2B6" modified="2024-11-27" version="1">MPHSSEVTPDDEIKVFQVEGEGEDEKECSKLHLNDVKTSLVTEVDEEDQHQQNAPSFLPTSNAPRSAAERVIGQPLCGGQEGDIGPFFPSFGFWLPHLNSNGPYGPRPMGGKKKKKNLNNLVLSPASLSVLTSKRDSLKAAGLSVEGGRRAGSMLLCGGSYADDSEVNCISPCPSTDSGKRRGGKQSDKGSGPLRRHTCTPVEHGTPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAC9</accession>
    <name>A0AAV4RAC9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein yippee-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">YPEL5</name>
        <name evidence="6" type="ORF">CEXT_349441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the yippee family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007489">
        <property type="protein sequence ID" value="GIY17261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="13"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU110713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY17261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14215" checksum="CF7A3AB9E68B89F5" modified="2024-11-27" version="1">MGVLFLENLGGNVIYQCFVCNTYLTHRGHLVSTRFTSSNGPAWLFKEVVNVTQGKAVPRNMVTGRHIVRNVFCKCCTERLGWYYEMTFTKGQEYKETCTILEVGLIREIRKNALDTVSGISVLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHG2</accession>
    <name>A0AAV4RHG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein KIAA0100</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Kiaa0100</name>
        <name evidence="1" type="ORF">CEXT_118541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007755">
        <property type="protein sequence ID" value="GIY19428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="523" mass="59603" checksum="8C6862AEBC36FB23" modified="2024-11-27" version="1">MSLLVQLKLKFFRDCIHLSGRIALLYQKLHGGSFECMQYYATVDAGVPSPTVDNVMWLSVDNIEERESMVISDLPDLVGSGHSVGGVVSSTVGAVSNPESAPTQLQRIVSRCGCQFFYASYGENMDPSSLEDVPPLPEDNDLWEQEVAVDCFTLTHHDLDICTNSLQYAMILDLVNNLLLYVEPRKREATNKLQYMRFQLQLCSVDDQRGPILQLQENIRSLVANLRRLEKRSLTQIIDSRSRQRASSQDKGVSTSRRSEVCFKHAQWRLTDADGQLGISDLVLSNFLYSKITKTDDSVEHLLEVGYIKMTNLLPNQAYKIVLQPTELQTKIPLDRQCLLRIFCRERAPVGGISIKEHLEVNVVPITIGLTEAFYKAMLKFFFPGRDTDKVDEEDEDPERAEKNHTFFSIKIPEVPIRVSYKGKKDKNIEDVHELSLLLSTIEYHNRTWTWLDLLMALKNDAKKILLSQAIKQKLLKSKNIPEKDNQPQEEEKAAILLGTQHLAGQDQTLKKGFLSRMRKDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S233</accession>
    <name>A0AAV4S233_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_286441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008790">
        <property type="protein sequence ID" value="GIY27241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S233"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8731" checksum="5304E6C061EF216F" modified="2024-11-27" version="1">MGVRTVDKDSFSEGYGNPKNRRLVFFFPLPLDKSHTLRRPENRCPTRRSDAPGSTAYCDICKTNIYAALRHNSVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2I4</accession>
    <name>A0AAV4S2I4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_480061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008856">
        <property type="protein sequence ID" value="GIY27802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2I4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="377" mass="39095" checksum="DCAD4E34D6F5A790" modified="2024-11-27" version="1">MSPPCYCLLSKSSNTWIHSAICTTNVTFRACQSKSITACQCRQYHRRLLTAWRVPSQVHPDSPFCGGGHDGDDHDGGHDDDRGGGHDGVRDGGHDGVHGGVHDGVRGGVRDGVRGGDRDGVHDGGHDDVRDDVHDGGGVRGGGGDRGGVHDGVRGGGGGHGGVHDDVRGGGGGHGGVHDDVRGGERDGVRGGVRDGVRGGGGVHGGVRGDGDGHDGVHDGERDDVHGGVRGGVRGDGGVRDDVHDDVRDDGGVHDGVHGGEHGDAHDDVHGDGDDHGDVRGGDGVHDDAHDDVHGDEHDGDHGDDHDDDHAYGHVHDGDDDHVYDGDHDHACDGARVCGDGRERVCDDGDDDGDGGVHFYPYNNNFLSEIFKFCLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S5S1</accession>
    <name>A0AAV4S5S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_301771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008977">
        <property type="protein sequence ID" value="GIY28709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S5S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="344" mass="40178" checksum="B2D2F76B28B5DDC5" modified="2024-11-27" version="1">MAEDQEMKFLVYQLIPNVMISTNLTDTKQTLDIESFGNVTKEIIKHLTRAVLMKMYINDVTWWRYVRENRHDFFNTEERFLSFVLYAVHVVNFRTQDIYERFIEAIATVLSIVYYTYETNIKILEYSPQILTVFFNSMLKNSFYKRGGWEQLTKHIKTQDYIICFKQIYNLAPQPDNVPLGMTIEGAKILESFRKNIPRMPIVVTAGEVQNHALTAKLVIEVMKAHEKDPSLPKCIFPSKDSDYIWCTTITNSIGREALVRFTKKLEMEIVAENYRRCRPLGSTENQKDFDCGIREDSEDLRLPEKCLSNTKAENNIEGSILDIINGIGYRFSTIKAIFDFLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7S2</accession>
    <name>A0AAV4S7S2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginyl-tRNA--protein transferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ATE1_1</name>
        <name evidence="2" type="ORF">CEXT_190321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009190">
        <property type="protein sequence ID" value="GIY30210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7S2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-end aminoacyl transferase N-terminal" evidence="1">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="51" mass="5913" checksum="0BA9590ECA6F8B04" modified="2024-11-27" version="1" fragment="single">MDKSIVEYFSGGHKGYRCGYCSSTDSCYSHGMWAHTLTPMDYQNLIDRGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9A7</accession>
    <name>A0AAV4S9A7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_325851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009175">
        <property type="protein sequence ID" value="GIY30112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9A7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11154" checksum="46F230D0374B2895" modified="2024-11-27" version="1">MLRKEAMKAISATENDGKNLLNPLRNSYSNSTTSTKTGSTKTRSKRKPTKNISVGNLRDYESISKCIIYFQHCANAKETTPHGHSLQHDNAEWKKEQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SD44</accession>
    <name>A0AAV4SD44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_573631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009270">
        <property type="protein sequence ID" value="GIY30737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SD44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9266" checksum="84D0DB80BAE35A59" modified="2024-11-27" version="1">MELSKALNPTLTNQPAITFWLANHDNYVPAMNNSFIFSFHNEFSAPLCKPGHPVPPRRQQRIIQESYTLRKCKNSHKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLL6</accession>
    <name>A0AAV4SLL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">enpp6</name>
        <name evidence="1" type="ORF">CEXT_450081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009729">
        <property type="protein sequence ID" value="GIY34131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="20947" checksum="61CF11B19CD56DF9" modified="2024-11-27" version="1">MSGLMANRLVLRPLVPQASGSNPSSKVYEALKDIPGLHVYLKDEIPEHYHIKHNRLTLPILLVASKNYYIRGLDIPGKSIPTGSSISLGAHGYDPYEVPDMRGIFFARGPGLKKNYISPPLQMVDIYSILCELLGIEPLPNNGTKSITKGIVALPYSAADRFCTIQHTPQVAAGVCIILCARLHHYITCLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNP5</accession>
    <name>A0AAV4SNP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">A-kinase anchor protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Akap13_5</name>
        <name evidence="2" type="ORF">CEXT_303011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009614">
        <property type="protein sequence ID" value="GIY33273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="273" mass="30408" checksum="2833A0B7D0A1208B" modified="2024-11-27" version="1">MYVKTPRTICTNIRSRVISFVYPEAGSEFLYPFENGKSTKNGPTRLSNSCPALYMTSGDETTVHLDGAAITMRNIQHRRTSLSSNSHSLDSTFIESFNVKIHVNDLTPAPSQEFFKSVLATSKRLAKKSNKKTPTRRQSWSSLGAVEAPEDQGKQLIQRRWSLSSLDSDTEDAFCKSNTTASFRSKNSRMYHATKSNNLSQVPREKIRNFSDGNCEESLSKSSKQSASVPSIDCSAADAKENVEPQKKRTVDKAKEDTSNRQSLSTMHPFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SP51</accession>
    <name>A0AAV4SP51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_155831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009973">
        <property type="protein sequence ID" value="GIY35880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SP51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="11171" checksum="9F4B01F44312DD11" modified="2024-11-27" version="1">MRLYIQLRTLLRLNPNTYCSSFCSRQTYACVQKFSETSGDRNHFRLYFSVRLKSEQRDRINKLKVERVIYLPISPHGYCMVDTFDSTFEAFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SPJ8</accession>
    <name>A0AAV4SPJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_256131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009808">
        <property type="protein sequence ID" value="GIY34796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SPJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12251" checksum="E83E088A23DFD1E2" modified="2024-11-27" version="1">MKIWHWKKTLKQKLASDYCYETVIFSTLIKQWLNARHKHYLILYKHWATLGVINKSMVEALITEHSSPSSTIPFTNQMVNFKKMISRIEELQNFPVLDLFDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXA4</accession>
    <name>A0AAV4SXA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterogeneous nuclear ribonucleoprotein U-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hnrnpul1</name>
        <name evidence="3" type="ORF">CEXT_367101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010399">
        <property type="protein sequence ID" value="GIY39083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000380">
        <property type="term" value="P:alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12884">
        <property type="entry name" value="SPRY_hnRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035778">
        <property type="entry name" value="SPRY_hnRNP_U"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12381:SF56">
        <property type="entry name" value="B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12381">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY39083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="22627" checksum="20548F06DB72ECCA" modified="2024-11-27" version="1">MEESASKRYKLFFPIQLAANTNSVPESGGTQDNYIPPSSSPAVVPDVPHSPVHIIGATSNLIQKLIMKIETEEIDETIVTLDTYNSDLNLVIDSSCYLAQPLTTEGFALMWAGARATHGSSSGKFCYEVKIGEHLDVSHLPADELNPHVIRLGFSVESSSLQLGEDEFSYGYGGTGKISTNSQFKDYGSPFKCGDVILALANMDSNKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY69</accession>
    <name>A0AAV4SY69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_502341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010383">
        <property type="protein sequence ID" value="GIY38985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15310" checksum="C7A9B95C6D3E48CD" modified="2024-11-27" version="1">MSLANAEPVSKRRETDNSLVSDQYTSSQVINSLDGLGGFTLQLSQKNSPVFFCVSSIRQNSPVQRTHSWVSQFSRGAPLTRVSDGHVELKIRAVNDGHCGVANSVSLLSSEADLHRRRNYRPGTLGSLLLNSHHSEKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T235</accession>
    <name>A0AAV4T235_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_228171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010502">
        <property type="protein sequence ID" value="GIY39749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T235"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17161" checksum="2C671B8B2DCB7C56" modified="2024-11-27" version="1">MLATAEVKPISGFDSQIVIAYVQNPEISRNSDCSKAHKWIRISDSNCIRAKFLSHVVKQRLEYESQIVIAYVQNPKFLKTATVVKPISGFESQIVIANVQNSCGFESQIVVAYVEIAKTEHSYCSRALKWIRISDSNCICAKTRKFLETATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2J3</accession>
    <name>A0AAV4T2J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_100171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010370">
        <property type="protein sequence ID" value="GIY38907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13154" checksum="E078F59F342E820D" modified="2024-11-27" version="1">MNLKPIKPCPQQLKVITLFSLKTGVQAGRMRIRIKIEVKNDHPPLISSNRDKNETGNWNINCAIHQVYVEHVRLNDNVTVKGYVVMPSSVVYDAFVTVKKDFSFNLEVIPTSAAGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2U4</accession>
    <name>A0AAV4T2U4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Regucalcin</fullName>
            <ecNumber evidence="7">3.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Gluconolactonase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RGN</name>
        <name evidence="17" type="ORF">CEXT_402631</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucono-1,5-lactone + H2O = D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16217"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="EC" id="3.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SMP-30/CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.17" evidence="7"/>
    <dbReference type="EMBL" id="BPLR01010524">
        <property type="protein sequence ID" value="GIY39877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019853">
        <property type="term" value="P:L-ascorbic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000027">
        <property type="entry name" value="Regucalcin homologue"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008367">
        <property type="entry name" value="Regucalcin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907">
        <property type="entry name" value="REGUCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907:SF47">
        <property type="entry name" value="REGUCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01791">
        <property type="entry name" value="REGUCALCIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="16">
        <location>
            <begin position="13"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="14">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00016808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY39877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="292" mass="32301" checksum="5AFB5D30ADF1B2A2" modified="2024-11-27" version="1">MSIKAVSERLSDLGEGPHWDVNTQKLYYVDAFVGDVCRLDPATGVTEAVHLDGITTFVIPYRSDPSKLLVTLNRQVRKLNFTTGESELLTELPPETAPARFNDGKCDARGRAWTGTLVPQEEEKGHLYRLDPGYVLTQISDKITLSNGLAWSLDNRTLYFIDSEGKKIYFFDFNLEDGSASNRQILIDYNEKEFEGLGVPDGMTIDVEGKLWVACFGGSCVLRIDPATKTILRKIEMPCTNVTSCCFGGPHFDILYVTTAKKEGVTDQPQAGAVFAVTDLGTRGQPPNDFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4P8</accession>
    <name>A0AAV4T4P8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_809341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010583">
        <property type="protein sequence ID" value="GIY40241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4P8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="26073" checksum="366E01CD81C77A19" modified="2024-11-27" version="1">MDLWCAGKLPQRGAMLLLSTFPSRAIKAAYLSVRHCVLLYYEHNLRNCWMYTQALLPCSGGSMRQCESDGLLCGSMHQLRIRWPRRACYGELAANAGSSRFLFHALKWISGELANYLNWERCLYFFYLPQPTIKAAYLSARHCVLLHYKHNLRNCWMYTQGPLALLQWIDASVAYPMVCFGELAANARSSRFLPRSEMDLWCAGKLPQLGAMLLLSTFPRTPLKRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8D2</accession>
    <name>A0AAV4T8D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_747511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010699">
        <property type="protein sequence ID" value="GIY41162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14870" checksum="2A6C0A23A8AF4409" modified="2024-11-27" version="1">MKEMEQKFLFSSFFHYYAHQLWVRDVTQRFHVITLDVTAAGSSHWPPSRRARVLRNLFTGMTSAMTLKMAEFREISSGVFFLGLLNSWQLLLSEHHMLSEVVFSPTTTNVVGILPLGEYGLAAYDKHCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8N6</accession>
    <name>A0AAV4T8N6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_329661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010758">
        <property type="protein sequence ID" value="GIY41797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043752792" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10964" checksum="10A74F668F8C1F0A" modified="2024-11-27" version="1">MPSSRCQMILQPTWWNSLILSLWAVARMPQFMPRGSDPRKRISSRRATNGGVLLVGETTEEVPGLSSEQTKSNARRCLFCASDMKIHAPYLGDRDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIW1</accession>
    <name>A0AAV4TIW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">AVEN_144111_1</name>
        <name evidence="13" type="ORF">CEXT_253101</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the transition zone in primary cilia. Required for ciliogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TMEM237 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011398">
        <property type="protein sequence ID" value="GIY46320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029409">
        <property type="entry name" value="TMEM237"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28388">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28388:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15383">
        <property type="entry name" value="TMEM237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY46320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="36520" checksum="C37BE40885C9EDF9" modified="2024-11-27" version="1">MSSTSIARQNRRKRQKQLPALPNTESTVPHGILSTSTSNPFVNNSGLYENSLSSESEQVNQETNVNDSGYNVNIIDENGSLSDTTGCSYIKCDVSSRPVGKVFIEDERRFRAVDPNQLFQTFNNDISQETESKTESAIDLGYKSARYFHNFSFLCHGLLGGMSFMEALFLIHLITTTEQEESLKHFQFLSQPIHNLFNFLCIICCVSAFDKYDIGNSKEFFKYLKKCKLKCIIIIIYPICLVLSFSTANVDEKLCLPNENSTIFDSFKIEDAENELFYWKTLSISKCVGALLAWLIISLEPNQNLFLCHLNNVLQNNLINAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQJ1</accession>
    <name>A0AAV4TQJ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_750561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011520">
        <property type="protein sequence ID" value="GIY47075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="20168" checksum="0CAE0DC88C6C40A1" modified="2024-11-27" version="1">MSFNQSRGPHFKPNQIHATINIHKSLVATSPLFHTRVSDIFFRDAPSAFEEGPLLEMVFTACRLHLPHSWVMWSPWQRSPRQRARGLPKLIIYEGGQSSGGRVRRIRPFVMRKSISSSLEDGFFFLPCLLFRKAFVFGKMKLYLPQRISGLDRIASLLEFVAVLELHLDNKTMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TV41</accession>
    <name>A0AAV4TV41_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein 208</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tmem208</name>
        <name evidence="9" type="ORF">CEXT_273691</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011942">
        <property type="protein sequence ID" value="GIY50125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TV41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY50125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19232" checksum="F27E64B6CC748CDD" modified="2024-11-27" version="1">MAPQKGKQGTKGQKQIVEENKQTLKFYSIMALSSELTYIGIMLTLFWESYTALYMFLSLATVLVFAGSLQFMHSMAGATYSETGQLLDGGIDLNMESGFAEHLKDLIILTSAIQILSLISSYFWFLWLLAPARAFYMLWVNVLAPWIFSPAPEVDEKKQKKLERKAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWE3</accession>
    <name>A0AAV4TWE3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_195289_1</name>
        <name evidence="2" type="ORF">CEXT_604131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011818">
        <property type="protein sequence ID" value="GIY49295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="268" mass="30990" checksum="00E72EAF80232A38" modified="2024-11-27" version="1">MEEIGDYNFSKIEDSETTKRYYFPYREKRLEEWINKEEDRPHKIRLRELKFSENSQLHLPDSSDVTSSQTCDETMQPENSKDHTLPKSYSFPFRRKPLRTWMEIPENRIENPEITSSMPHWRTFDGSIAEQKCKIRRSLSGSELAAEDPDSKAKYDKHKSFSQSVEISNASNPLSGESSKDSPTAFDKIKLGFKNCVTRVKKDSFKTNATKPLVKKRVIKKSIFQSKENVCADLTQSCASSKSLMNDHLNRMSSSPSYPGYLSFEKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWN4</accession>
    <name>A0AAV4TWN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_236902_1</name>
        <name evidence="2" type="ORF">CEXT_53921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011739">
        <property type="protein sequence ID" value="GIY48648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="454" mass="52477" checksum="263B317D62D03EA9" modified="2024-11-27" version="1">MNWMGGARSRIKAANDKKKQREFFEKRRHAAPQASAIRETKTVPALSHDLISFYLSERNLKRNLPISKPTQVIKEDLVKRSSNIVDVDLSETPLERIPSFHGKNLSQGWKIKMPKEVRHTPDETFFSQLNLDTKHTKNSQGNQLRHLSHYNNIHYDGNDSPAQDFTMKEPDIQTSLFLNGSSREEFLLPTELSQTPDIHESFKRYLYLDKMNESKDGHKFSHNIDLDFSDSTLDKAWQKALHQEMKQMEKTYDSSKRKPFKRSKVIENIDTYLSRRQHGGLQSSKNSQPSFSDLSKCTFSSIPMKVSRNSEQDSRDIDLNDNSEPSNSVNYKHRLRELEEMIHKASRKKQSPKHKYELDVSPKCGSDKCEYFSVANLYQSPLDSTSSSSSSGMSIPVFFQKKRNRNDEQTFNKCNITSYKKIKRSFTDAHFDVGKSVVNHKKKIKISNTTVLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZG5</accession>
    <name>A0AAV4TZG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding cassette sub-family A member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ABCA1_2</name>
        <name evidence="3" type="ORF">CEXT_456211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012020">
        <property type="protein sequence ID" value="GIY50747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY50747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="347" mass="40140" checksum="48F7BF5BB59A95D6" modified="2024-11-27" version="1">MTGINIPQYLLDSYLQFNEKRYGGWTIGKKNRPQETRQDYGIRTWSHPLRLSVEQLGRETLLQRLGEVGIAFVFLIGLSLVPCTFAVYVVGKRIGTEATPDGDWGPGPLALLDGGLPVGPHHRLGHQRHIGGHSQRFRLTCFLPKRELQSSLHSHFPLRVGHNSTNLFVQSFLPRRKLGLHGHLHEPSVRWARHYDVTRQPQDDQCVQRCCIYFDKFADVFLGVPSIQPGRRSDRPERESNKNRNIRTIRSRCVHFPFQLELPRSQFRRPLHARGRLFSSHSPLEVIPLRHWCQSGLKENKRSNPKSKVRGHRPIRKNIQRFPQNSSSDNFKKTAKRHPIDLCHTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1G5</accession>
    <name>A0AAV4U1G5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_340471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012134">
        <property type="protein sequence ID" value="GIY51633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1G5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10541" checksum="EE04CB7EA8816C64" modified="2024-11-27" version="1">MDAMGLQQLLMLPSESNRLPASYQLPLCVQWPSIFSTKDNYNSRGMATARPATMKPVVPDRYSRDVRTSLLSVTSTITSRNFFLSNIVSKGRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3J9</accession>
    <name>A0AAV4U3J9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_36651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012220">
        <property type="protein sequence ID" value="GIY52295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3J9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="14747" checksum="306BB37FB00AA4E5" modified="2024-11-27" version="1">MILDISPAEALLSLLSKFRGYLEVSEIAVTTTFEMASHLKVSNRFARWALEIQSYDIKNIVQSRQSAYSCKPLKPPCLGYGGYGGYGLGYNRYGGYGGYGSGYNRYGGYGGYGSGYGGYGSGYNRYGGYGYNSHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6V7</accession>
    <name>A0AAV4U6V7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_628631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012367">
        <property type="protein sequence ID" value="GIY53446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6V7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9160" checksum="E0CAE6A53F19CBF9" modified="2024-11-27" version="1">MKRTNARKEKKEHVHQPLLMKWGVTRTLIVSSIFSEGRHRVPVAARRRSTPGRREEVGRATFLATGTEAAPPREQKTGLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAJ1</accession>
    <name>A0AAV4UAJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_77361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012558">
        <property type="protein sequence ID" value="GIY54809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="20729" checksum="4E47584AF5CED19E" modified="2024-11-27" version="1">MAECTKKNACGINVSRLGQEEVPKRGMITIIPLFECDGSIGPQGESRDSRRSIGCGCGYSTPFFPPPLKKKMSALTLLIKVERCQRVVGSEFRIRENSFRESEQHSQTFLHIQLLYSDNCHLNRKKKTGLGGNAKRGMIAMIPLFECDGSISPLGESRNSRRSIGCGCGYSKPFFPSTLQEKMSALM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UIQ1</accession>
    <name>A0AAV4UIQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_312681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012927">
        <property type="protein sequence ID" value="GIY57584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UIQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10587" checksum="BCCD301175FFF560" modified="2024-11-27" version="1">MVGDGSNISFTVYIIRFRMPFLFGFLSFILPRFACSPVGGVAVVDQSDIARFPLIALLGQHDMDGKTCIQRLFVQLDKSIFPDDASRFTFYRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPB2</accession>
    <name>A0AAV4UPB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ryanodine receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RyR</name>
        <name evidence="2" type="ORF">CEXT_813971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013186">
        <property type="protein sequence ID" value="GIY59265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034704">
        <property type="term" value="C:calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033017">
        <property type="term" value="C:sarcoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005790">
        <property type="term" value="C:smooth endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030018">
        <property type="term" value="C:Z disc"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005219">
        <property type="term" value="F:ryanodine-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014808">
        <property type="term" value="P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006941">
        <property type="term" value="P:striated muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015925">
        <property type="entry name" value="Ryanodine_IP3_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048581">
        <property type="entry name" value="RYDR_Jsol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399">
        <property type="entry name" value="B30.2/SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399:SF8">
        <property type="entry name" value="B30.2_SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21119">
        <property type="entry name" value="RYDR_Jsol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ryanodine receptor junctional solenoid" evidence="1">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY59265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11255" checksum="8EBE09337FC852D1" modified="2024-11-27" version="1">MFQGNHRAAHIICGHVDEKQLQYAIKSEYMSGPLRTAFTDLLIALHLEFHAYARSLTQNEFIVPLGADLRGMYEEPASAHSLSTMQYSSIRPEMTMSPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQ67</accession>
    <name>A0AAV4UQ67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_628111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013251">
        <property type="protein sequence ID" value="GIY59879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQ67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10896" checksum="D66418C96B119A59" modified="2024-11-27" version="1">MIQLQPLPVQYLCWGRGMAEDEERERGRLDRWEDSDSWRAVDVKRTLCFYFFTSPFRNLQTPFSIHTCFLRWELSKTDPSFPYGPQMSTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQC3</accession>
    <name>A0AAV4UQC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Mtor_2</name>
        <name evidence="1" type="ORF">CEXT_707861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013272">
        <property type="protein sequence ID" value="GIY60055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="50" mass="5658" checksum="CDE24EC310B1152C" modified="2024-11-27" version="1" fragment="single">PLPLKSTLLGEKAMECRAYAKALHYKEEEFHKGPTSEILETLISINNKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT49</accession>
    <name>A0AAV4UT49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_204191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013395">
        <property type="protein sequence ID" value="GIY60903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8273" checksum="C94E551F5065C7E1" modified="2024-11-27" version="1">MKPDFHGSAKCSSATRHRIFSNRLDDDADDHWRVLPWQQLQLLGGMNSVRIFPFERGCVRVEFERKEIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VD22</accession>
    <name>A0AAV4VD22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_364671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014306">
        <property type="protein sequence ID" value="GIY67973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VD22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15065" checksum="BA82E702815454BC" modified="2024-11-27" version="1">MGGPDMRFRPSRSSGVVWAPLEPSFDVCFSVSSTASDEVARQHQQMVSALSTITKHPGAPVPQPKGPPLIQISHQSRCEEESTRPPMDSPSCKTEFTFLQIAVISVRVEARRDLQRSTHAGVIYSWASSHARLPPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VE28</accession>
    <name>A0AAV4VE28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_6121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014290">
        <property type="protein sequence ID" value="GIY67879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VE28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY67879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="418" mass="47739" checksum="522F838902AE7DDC" modified="2024-11-27" version="1">MDDKQKENDEKSSSISDDGSFSNPDNFEAIGNPNSVVEASTQTISEVGCPTESDDILDQCSSTSGHNMVSEIPGSEVTEHPITIERDDRCILDSIPGLDLISEEDKFHLAKYSEQYTASEYSHGGNIAKAVVVNWPGVLPAVPETAKRNEEDENEERKKMKWRRKWRRNREGEVYRYYQLLACVEHQPTCLRFSLGDALAFLVVYSLLFAWPIAIIYMGSQCMKQCPMNQYLPYAMMGRKYGYFGIFTRFSVSLYIQCSSKPLQANWAKIMVHLLEFVFPQFLWCFKPPPGKLGEDYGSSPGVVFLNFFGALLQQTPPGKLGEDYGSSPGVCFPQFLWCLSLLFYEQIPRFEPSVPVYCNESFYKSTSWMNYASSLLIIVWGFSVFYKISTMDTKKKRRPILTTFKTSALYKFLMNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VH79</accession>
    <name>A0AAV4VH79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_379561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014528">
        <property type="protein sequence ID" value="GIY69403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VH79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9550" checksum="6FC54169CCC37A5E" modified="2024-11-27" version="1">MPEKALLWNVSSSSRFYKDTQIGRKKLYPYPPLFKESSEVFVCDDVEPIQSRMFLIPCYRQLAIFGTKGRQETDERVGKNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VK19</accession>
    <name>A0AAV4VK19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_496671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014646">
        <property type="protein sequence ID" value="GIY70295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VK19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="54" mass="6237" checksum="F7C0679FC63FE17F" modified="2024-11-27" version="1" fragment="single">MQYTKTQHFRDEPNTQSTKVAERVTRRRVTAGLQAGSQKADDMRKLQKCNGNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUW2</accession>
    <name>A0AAV4VUW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-binding cassette sub-family G member 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ABCG8</name>
        <name evidence="7" type="ORF">CEXT_120401</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015095">
        <property type="protein sequence ID" value="GIY73529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF89">
        <property type="entry name" value="FI03229P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="107"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY73529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="413" mass="46235" checksum="56B310FF55F8164F" modified="2024-11-27" version="1">MWEMSTMERRYSVPPSTLSDPSGRCRTTEDLHAWSIYRQNLNSDFTDSALDTGHKSQPPFGNFRLRESTVQTILNHPKYGPRERNSELGSNVFTYLRFGLPRVLPHPPAAKPLRNGSSGYDSSDDNASPYLDRGRRARSDPDFRNHVIPPPPPGERKSGGSRLKASSEADLLAADSGGSRAHSRQQVMRAREEAREGYQRNPMPGNGHAAPPASKAGSHLSVNSRMSPDQSSYRSPGKLDGFYHDAPMLNERFFPKDNFYSTLPGASSEGGLPRYPHLQVRDLSYELDMSSAWHTLCGGARTKLRMLEGLSFEVKGGEILAIMATTESEGTALLDILANRHRKWRCRLRGEFMINGLYLTLKKLDKCVAYVQRHTDFGPDMSVRQTLLFTSLLQEPDNNRGFDTKSRGGLKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2X7</accession>
    <name>A0AAV4W2X7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SH2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_163772_1</name>
        <name evidence="4" type="ORF">CEXT_111501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015472">
        <property type="protein sequence ID" value="GIY76321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2X7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00173">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15832:SF2">
        <property type="entry name" value="SH2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15832">
        <property type="entry name" value="SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0727">SH2 domain</keyword>
    <feature type="domain" description="SH2" evidence="3">
        <location>
            <begin position="300"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY76321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="432" mass="47984" checksum="40741411C692D152" modified="2024-11-27" version="1">MRYASSPPSMIRSGEGGYFLITVLALQRCSSYPITGVFLFSTRSSEDTETEQLSLLFHLSLPSSFRLKKLAGKTKHRDPVTNQNMELSNQTFSANISECSGASSPPLSPVNSCKSNQCTPNNLPLDLWSPLGGASSCEENNSPTDVNSCKQIKEKPPLLKNLEVVKENVLGDESFSHELPRPLSGGYINESSSWESPQLRLPKYNTSGRADGFSPLKKFSLGSRSHIPSAPPTDEESLLEMSTDQSSKRSSRSSCDHCCKSKRINHNDSTSSITPPPPPERHDSLYIADSEERELRAAPWFQAGIPREIALEVLALEPVGSFMVRQSTSKPGCFALSLRVPRDFHQTGIAHYLIMRTTRGYKIKGFTKEFCTLTALITHHSVMPELLPCPLSLSRYNPTFRRQDSEDMVDIDEDPDYNLLSDFRKMLADANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2Z6</accession>
    <name>A0AAV4W2Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_194851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015394">
        <property type="protein sequence ID" value="GIY75825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="22463" checksum="860A37C6B9D792F9" modified="2024-11-27" version="1">MYLEDKKGGEDSEIGFVGRRLTDSLKQRNLQVDKIVLICDCCVGISAIVLLFWICVACCVKSNINYSPSDKGCRDRRIPTSCSISLQGRRSWGDDIPLGQQWSLTNASRDALWAFRGNRKEEGVVLFRNWTLKGHHLSSEHRSVHISEASFYPPMLFCCCFNSLGCWLLSFFGFVLSLDKKAFMYLEDKGGGFRDCFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8K3</accession>
    <name>A0AAV4W8K3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_572331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015848">
        <property type="protein sequence ID" value="GIY79122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8K3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15373" checksum="690F3E402A0A5A79" modified="2024-11-27" version="1">MQHKEAGSLDITPIEMLVYNCIMRETHKIYASIPPLSSCPTERHVSVAYTPGVSCQGKWINTYCWGPLCQLSPTVEFDIAQSVFSVRQEQRERIPPPCSLSNRTIPSPAITERPQMGWGEWRAGSLRMGRMFCLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEP0</accession>
    <name>A0AAV4WEP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_763751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015928">
        <property type="protein sequence ID" value="GIY79770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10761" checksum="B78FA8610421C4A4" modified="2024-11-27" version="1">MCSVTTPTPSSTSLDPSRDLFSLAGVACDDDDDDGDAQLHLRRCLFLCLIQRKLKTKDEAAKVKARAGEAKTHCRVKVCVKQMHHVVKNKVVSYEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLF1</accession>
    <name>A0AAV4WLF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcium-activated chloride channel regulator 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CLCA4</name>
        <name evidence="3" type="ORF">CEXT_764731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016419">
        <property type="protein sequence ID" value="GIY83721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY83721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="31450" checksum="F4F6E9C932E5355A" modified="2024-11-27" version="1">MQEFEPENFDVVDKNSTEGAEEEFETKPANKFDRSSNGGAFRMEAWTPDVGDVIPPGDITDLKVLSADTETMQVTLEFTTPGDDLDIGNVTSLELRTSNNPEEFVANFDSGLLINETFIVKGTLHPLGPGEKTDLIIKLPETFSDAEPHTVYFAMKATDDVGNTSTRYNIAPATFGMKAKIIRGIKEQENEAKSSKGMKKGEEKSHEENWPSKDEFVKGHESDSMAQDQKNDEQEESGKNSKWWPVIVGIGTAFTVIMIAVLIAVVIIKKSKKRTYSSVQSQQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVY5</accession>
    <name>A0AAV4WVY5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_27241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016707">
        <property type="protein sequence ID" value="GIY85875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9242" checksum="C9FCE00ADFED9E92" modified="2024-11-27" version="1">MSKYCGATAPKKSLGRQYPLNLDSQWVNSEYKRNFTWHDGYQATKVDVVRNAPSVRAADENSNKISENREKLLPAVGKYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXS9</accession>
    <name>A0AAV4WXS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_253151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016878">
        <property type="protein sequence ID" value="GIY87053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8291" checksum="6BF3D6B04A362C58" modified="2024-11-27" version="1">MAIPSSWDMPGVSAFSAVFAARFKRACQAALDGYRLLQGLFLRKETGRLELHSVWWRSKHPLLESFPVLSARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2K5</accession>
    <name>A0AAV4X2K5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_63161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017188">
        <property type="protein sequence ID" value="GIY89337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="201" mass="23201" checksum="7E351393C73A32DA" modified="2024-11-27" version="1">MLVLPKQYAFSMRRRDVSDDKPFRGRLLRALVLRNVVIRSALILVKGNRAITKVKFVKIHRDDVLSYLDLSSVALCLCTFMISKWILKRVVCSVGDEICDVQFEYKREGEDAARFDISLDDQSIYSQHPHLIQHHRVIPVKFTSNLMAFSAAHLSRFNIPIVIPAPQNILHFPQFYVCLPTDILFLLPKPYAFFDEAPGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X450</accession>
    <name>A0AAV4X450_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_618841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017196">
        <property type="protein sequence ID" value="GIY89363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X450"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10108" checksum="393FED898970B4DB" modified="2024-11-27" version="1">MDKITFPPLSSLKLIYSNAAVTREKRAEQKDAFEKKKKKKAVFIAEAKQIKHSLRKGNIRKRESNPTREKKFCCSKYIWIFQSFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4E4</accession>
    <name>A0AAV4X4E4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Tf2-6_70</name>
        <name evidence="2" type="ORF">CEXT_680811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017203">
        <property type="protein sequence ID" value="GIY89417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4E4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="13"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21862" checksum="747F5F25C8CC8E77" modified="2024-11-27" version="1">MWEEGRIFKPHPEGGVPLSTYHVDFIGPLPSTNKIYQHIFTVIDAFTKFTWLYPVKTVSTRDGLDKLKLQQKTFENPLRIISDRGSAFTSKAFNDYCTEEGIQHLQIATGVPRGNGQIERIHLTLIPVLTKFSLEDATKWYRYVDKLQRILNSTMNRSTKWTPFELLTGVKMKNKEDIKIISLLEEETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9V0</accession>
    <name>A0AAV4X9V0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_180931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000007">
        <property type="protein sequence ID" value="GIY91397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9V0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11402" checksum="3E7C8E77AED47F30" modified="2024-11-27" version="1">MTRRAEKYFGWKGLPCTLFICPTSFPVVCSLALRHLSVRLVVGIWGERKSGMFLTTLRHPSVRLVPGICGAKVGDVPDKGVSGCTEEKVIREIMKDDLRRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBA3</accession>
    <name>A0AAV4XBA3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphatidylinositol 3-kinase</fullName>
            <ecNumber evidence="2">2.7.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PIK3CB</name>
        <name evidence="13" type="ORF">CEXT_167241</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12709"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.137"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.137" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01017418">
        <property type="protein sequence ID" value="GIY91475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005942">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016303">
        <property type="term" value="F:1-phosphatidylinositol-3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035005">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032060">
        <property type="term" value="P:bleb assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043491">
        <property type="term" value="P:phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050920">
        <property type="term" value="P:regulation of chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05165">
        <property type="entry name" value="PI3Kc_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000001">
        <property type="entry name" value="Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000008">
        <property type="entry name" value="Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002420">
        <property type="entry name" value="PI3K-type_C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003113">
        <property type="entry name" value="PI3K_ABD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000341">
        <property type="entry name" value="PI3K_Ras-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF118">
        <property type="entry name" value="PI-3 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00792">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02192">
        <property type="entry name" value="PI3K_p85B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00794">
        <property type="entry name" value="PI3K_rbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00142">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00143">
        <property type="entry name" value="PI3K_p85B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00144">
        <property type="entry name" value="PI3K_rbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51547">
        <property type="entry name" value="C2_PI3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51544">
        <property type="entry name" value="PI3K_ABD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51546">
        <property type="entry name" value="PI3K_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K-ABD" evidence="9">
        <location>
            <begin position="26"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K-RBD" evidence="11">
        <location>
            <begin position="198"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="C2 PI3K-type" evidence="12">
        <location>
            <begin position="329"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="PIK helical" evidence="10">
        <location>
            <begin position="522"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="769"/>
            <end position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY91475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1070" mass="123866" checksum="98E217ABF653FF61" modified="2024-11-27" version="1">MGTELNPYMMVDATTSSVADAWTLGQDSDVKLDILLPNGCFLDITVPRDAQLKEIKEKVWERAQHYPLFCLLRDRNSYVFQCVNLLTADRQDQTQENQRLSEVRPFQGMLRLVEKKENEVDILLNNRLNYAIGIGQREFDNQTDPEVSDFRQQMQQFGESVCAALGPATWEQRVLRQYPLALESNPDLPNYLNDKLLEGKLMVSVEYKASESTFKFYVPPSYNAKELVSLVVKKKGPSIGLDTEYVNNFLLKICGVEEFLIGPYPISQYKYIRECLASDKTPELILVTTEMVYLEFYAKEIRWEERQRSLSTTSETSTPEQDKMSTWSVSDPFTIKIRTIHRLNYDSKIKVAVQCGLYYAEERLCNRVYHTSEKVLEEGGYCSWDETICFDLEVCNLPRMAKLCLVVYETSTTQKNSRFRKCQDKYACPIAWVNTTVFDYKGVLKSDSLTLSAWPYPQESDEYSSCMLRPLGWLTPNPCKDPSLVVSFEKYYPSVQLVYPELNEILEYANRDMPDRNGSFSSSGEPQASKSHLQQLQQICAKDTLYQLHEQEKELMWFLRKHCCVQLPNSLPKLLRCVKWGDRAEVAQMMKLLQRWPPMTPYKTLELLDYTHPDPLVRSFAVRCLRNISNDELSLYLLQLVQALKHEAYLQNSLAKLLLERALQNRHTGHRLFWLLRSEIHFPEVTIKFGLLLEAYCRSEPSHLEALEKQVLALSHLKSASTEASKAKKESKDKLKNYIKDIIGKTRFQSNLFGLQNPLDPRFKFGKIKIDKCKILDSKMKPLWLAFENTDSNGKDVFLIFKSGDDLRQDMLTLQMIRIMDRLWKDEGLDLRMIPYRCMATGNRVGLIEVVPDADTIANIQKEKGSTAASAFKKGSILSWLKDHNPDDISLSRAEEEFTLSCAGYCVATYILGVADRHSDNIMVKTNGQLFHVDFGHILGKFKEKFGFKRERVPFVLTHDFVYIITKGQNQRSQEFSRFQQYCEQAFMILRRRGPLVISLFAMMLSTGIPELTSEKDLDYLRETLVLDMSEQEALKHFRTKFDEALKNSWKTSINWLAHNWTRNNTISEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC12</accession>
    <name>A0AAV4XC12_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein O-mannosyl-transferase TMTC3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Tmtc3</name>
        <name evidence="6" type="ORF">CEXT_694151</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017425">
        <property type="protein sequence ID" value="GIY91515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013618">
        <property type="entry name" value="TMTC_DUF1736"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44395">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44395:SF1">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08409">
        <property type="entry name" value="TMTC_DUF1736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1736" evidence="5">
        <location>
            <begin position="43"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY91515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19041" checksum="F75EE1B1431F8EE4" modified="2024-11-27" version="1">MRYLMLGRVSPWLRDKLLRVFLLLTAAAGALYLRCKIMGPKILPSFSRFDNPAAASATPTRQLTYNYLLSVNAWLLLFPCNLCCDWTMSTIPLITSFWDTRNLATLAFYVFVFLAARAIFKLEEDARVSLMMSLSLLVLPFLPCEQPVLPVGFVVAERCSTFRAWDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG13</accession>
    <name>A0AAV4XG13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_395401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017579">
        <property type="protein sequence ID" value="GIY92718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9514" checksum="E791E64470A14F3D" modified="2024-11-27" version="1">MFLIDSYRREIKKIKMSSDGAPRVGLFLKVAGVTACFNADLSRTSPGAAGSMGRRDAQRQEDEEQSGRRERCCCLLSALAASSTRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSG3</accession>
    <name>A0AAV4XSG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_157871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000866">
        <property type="protein sequence ID" value="GIY97991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12387" checksum="66DCB6BE0B518BC4" modified="2024-11-27" version="1">MSNQFHVLSFEVPFEFRIGGGSKRPGKKCQGWKSLRQEGGQHLGRPLMFLYRTRFLVGEKRIELRIVPTGPQRNSSQQTKQRKRGGEEVDQKEIEGLINPSPSHQGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVB8</accession>
    <name>A0AAV4XVB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_406911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000993">
        <property type="protein sequence ID" value="GIY98996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11893" checksum="69DCA58AC6F9F2D2" modified="2024-11-27" version="1">MAGNDSNVVEGRILTPLSAYKSASFSLRFVGDKGVELTWKMENYCPNKAQVKVCQNTFPSLASYWIRSSQRTMKDVEKKDALTLSDACIIRYKIESVRENFRME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0D6</accession>
    <name>A0AAV4Y0D6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018558">
        <property type="protein sequence ID" value="GIZ00548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0D6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10530" checksum="DE4FF52801909ABB" modified="2024-11-27" version="1">MHAAGLDGAPMSGTVLQEAPSVSGSRLSISGKCSPFNRVAAHNKWLSRVSDRQCSLLQSKSKLRLLNSMSESKPKNHGFFVGNMPVNPICQKFLLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3K7</accession>
    <name>A0AAV4Y3K7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_221411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001332">
        <property type="protein sequence ID" value="GIZ01658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11968" checksum="8A15AE79B67FC3DB" modified="2024-11-27" version="1">MIPVLDSYEHGVLCMNAIIMSRLVRKEVVNPSQSKILCFKCGEFKYGRKGTGWDTQSRTRPRNSGGPYLMHHAWSGMRPIRRTRRSPQISRRPKGFSFKDAQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3L9</accession>
    <name>A0AAV4Y3L9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_509541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001244">
        <property type="protein sequence ID" value="GIZ01040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18677" checksum="AF94298CC1344C06" modified="2024-11-27" version="1">MLPLLKVYYPNGKDIVNQTLKHGKGSLVVMCNLNRSDGNPDGFLKNWRYCLLLDQSKASKFFRQATILGFFSPIAWRIKHISPNPATNPTSVFDALLICFSRFARDLEKLFGVADCSGYTVSKLSRISLSTELVECECSVDGNCTFITAVLYLKRYPRPNKNKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3T5</accession>
    <name>A0AAV4Y3T5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cation-transporting P-type ATPase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Atpalpha</name>
        <name evidence="5" type="ORF">CEXT_474281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018624">
        <property type="protein sequence ID" value="GIZ01091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3T5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF13">
        <property type="entry name" value="SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="4">
        <location>
            <begin position="39"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ01091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="257" mass="29739" checksum="125F2868ADFA9329" modified="2024-11-27" version="1" fragment="single">LQYDKTSSGWKALSRVAHIYAGELNLPVKRMFLSLKGTVTILCIDLGADMVPAISLAYETAESDIMKRQPRDPKQDKLVNERLISMSYGQIGMMQAAAGFFAYFVIMSENGFWPGRLLGLRKEWDSAAVNDLKDSYNQEWTFKDRKTLEYTCHTAFFVSIVIVQWADLIICKTRRNSILHQGMRNHVLNFGLVFETALAAFLAYTPGMDKGLRMYPLKFNWWLPALPFSLLIFVYDEIRRYILRRNPGGWVERETYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3W5</accession>
    <name>A0AAV4Y3W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001347">
        <property type="protein sequence ID" value="GIZ01763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10685" checksum="03F3BC13FFD1EB1B" modified="2024-11-27" version="1">MSCFWETEREKRHDVMVTYRKSRPMLSFDFLWLLESKSHVCFLAKRKKCISNPDNIFSCDKPLEGNMLKLPMMSCSLLERVNLLIVMYCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y650</accession>
    <name>A0AAV4Y650_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EF-hand calcium-binding domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">efcab1_0</name>
        <name evidence="3" type="ORF">CEXT_632351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001325">
        <property type="protein sequence ID" value="GIZ01629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y650"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ01629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17592" checksum="CD68D1E89A89200E" modified="2024-11-27" version="1">MSILKEYMDDMEFIDAAIFSEILHNSLGFLNDFSIKRVCFTCFDISDNLELAREDVIFLLLEAVSEPPTKDATTDALRDLVEMIFTKMDEDGDGVITIEEFEKVCMKDWTLMEMFGECLPDYRVSSSAFIDHRAAFLVLLESDQEIKSDKTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9P9</accession>
    <name>A0AAV4Y9P9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_191441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001629">
        <property type="protein sequence ID" value="GIZ03619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9P9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8889" checksum="6477AD33F6A39AC6" modified="2024-11-27" version="1">MPGSFGMHQLAGPGPIYRGFQSEGLPFPQDGSLHLLVSVVRHFLHSAVCRGAFSLTLVWRWVVQLKLGPTEAAEGHRIPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAF1</accession>
    <name>A0AAV4YAF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_385991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019090">
        <property type="protein sequence ID" value="GIZ04471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15812" checksum="6FD7B454700E8749" modified="2024-11-27" version="1">MPARLTDSLPTGITTQTPAEDPSQASPAPSAVTGQVEAVSPSKLRFRRLNSTFRWLLWKQKKQKEIKRPQGEEELFLTHISSESNYQQRTENIPFCFQNNLCLPNTYFQRSFESRLGVGGRKSCRNSACLEYGILGTSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFK6</accession>
    <name>A0AAV4YFK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_31671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019228">
        <property type="protein sequence ID" value="GIZ05165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="224" mass="25251" checksum="4A90C6A760774B7B" modified="2024-11-27" version="1">MLCRRIIDYHIPTTNRSCITDARRDALLSQKKIASMLPSCIGADGSSISDCSLEKQIQARATISDGTSGKRALYKRSRLNARMHLCVLRYAPGTQLRYHRNNGCVLPNSRKGKQKPEEGFPNRSGNNDTPSNTHLGRKNERLMRQRNIKRVLGAVPRRAPTESVNPHSEQLAMIRSSRKFVNCLPLGTGATVDCSGGAFCEKFTIRNFFLLYPFIREVFEETKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YG70</accession>
    <name>A0AAV4YG70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_164582_1</name>
        <name evidence="2" type="ORF">CEXT_116011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019256">
        <property type="protein sequence ID" value="GIZ05274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YG70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="45994" checksum="F6018C7755318E6E" modified="2024-11-27" version="1">MFSLREEDIKSRSDYPDIDDLSSFFDFDLGTTIESNEKDYPSRYGRPNTSVLGEGEEVVTISVNDSKAVISQAVVGPYQVSVVDANSPMLSELGAASVPSATYAENPRPDYPQRGYSPNHQHQHQHPPNTHSYEGHHHGPPDHTERQYRPNDYYPADNHPPPRNYGPAPALAQPPPQGSYDAKKVTQLSKTPLINTRLVTIMDNHLLPNHNLHTTSIHHKHTINILHHPITTIQLHNLLMLQSEALKNPGGKFPLPNILIGMTNRTKNQNTAHTMYTLHILHQYPIAIHHPTQFLNTRNPRMDLQTNLDTVMPLTPNLKQLTVLHHLHPVSINLKNQVTIPHQDILLPLPKLHQELELLSYASPSHHHHESYSESSKPGITIRFKGQISISPWRWWRWWTEHSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M2U4</accession>
    <name>A0AAV4M2U4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_335791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019339">
        <property type="protein sequence ID" value="GIX66772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M2U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX66772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15422" checksum="1AA5A0F97CBAD4C4" modified="2024-11-27" version="1">MRLTDSNPPNADNNPDPDSGETTEKLLSLLSLSLCLVLMIQIFFIRKYFQNDLKPLHMQFHFPYINHTENESRKIKAFKKTLTYRKITFYLLFNLEHPPNDFTFVPIKMNLKEKNRKRHCPEVVAGALSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5X5</accession>
    <name>A0AAV4M5X5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_226681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019340">
        <property type="protein sequence ID" value="GIX66806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8850" checksum="1A2CD6F4EE751242" modified="2024-11-27" version="1">MNSKPIPDSLCHPIKKYLSVAFRLLRVISYGIMSCVEDKSIRFISDLDSPSHTSTSTIEAFLTSILIRFDNMGIQRIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M689</accession>
    <name>A0AAV4M689_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_302171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019393">
        <property type="protein sequence ID" value="GIX67350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M689"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11277" checksum="52000B3B9DC3B6E7" modified="2024-11-27" version="1">MSIEYSKRTKNSSEETLAMRGINEVRSIDHFRLITSFENSAGIMKTGTRKTLILMKLTFTPQHEFSPRRLGLLNDAPIKCPQRIVLGAFMSCYRTPPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MI42</accession>
    <name>A0AAV4MI42_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_21941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019813">
        <property type="protein sequence ID" value="GIX72008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MI42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF1">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="3">
        <location>
            <begin position="79"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX72008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="279" mass="31801" checksum="FD598FEDA2430BE3" modified="2024-11-27" version="1">MLSLRVPLSVQDWKTSLQDYIKKKRNFRYTVFTASGPDILVEFITSNAGPLLNTGFHFKADSIIDPDTSEPLQLRNNSCFVERYLPENKESTFSNLRSWYPPNTTCAYRFYTTPEDVIRLDFLLFRIERFTMCEESVKLYDSSEPSPTKIITKLCDMNKAQAVYESTGHYLYVEFVSSKGSLDGSSISYEFQVKSVGASSLESGHACNRIMDHDGELILPLHELNSTSQPVTCNYTLDASSLMHGRVNLTLEVPFEKMTNTCLECKTESVVFRNNWCDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MND8</accession>
    <name>A0AAV4MND8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_522581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002458">
        <property type="protein sequence ID" value="GIX73936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MND8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14413" checksum="8864443A64FC0E75" modified="2024-11-27" version="1">MSPPGYEPEACDQRAGHLATRTPTSLDKDKGLRPRKSEVPQGCRSEDTRSQRHRSAPPSIAFGNYSSNYRWGARGPFDRMGRELEILGQLIIRTVIAPPTPLPRRKSMREEIEIGVNSKSSPVKTETVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNL2</accession>
    <name>A0AAV4MNL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_18911</name>
        <name evidence="2" type="ORF">CEXT_528061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019963">
        <property type="protein sequence ID" value="GIX73534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006621">
        <property type="entry name" value="Nose-resist-to-fluoxetine_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF0">
        <property type="entry name" value="O-ACYLTRANSFERASE LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20146">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00703">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nose resistant-to-fluoxetine protein N-terminal" evidence="1">
        <location>
            <begin position="14"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="208" mass="22816" checksum="794200E8AF77BF11" modified="2024-11-27" version="1">MLPTLMNNNDNSISSQCTGAMMKYIAGLTSVKVWAIRMLDATSKPPSGIFEGTLVDFGGFDQCLKVEFPKRNGDIEFRGKYCAIEAKPIMPPVPSNFSMARNSQAKPLDSIREEVKIAGTALNYLKFRLGVCVPSKCTLEDMQAIAKRASEVVKMDVKIPQCYVQETVAFKPIHVAVMTNRSDKNINKKTICKAVGQGKLASLAFVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUR6</accession>
    <name>A0AAV4MUR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_11281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020135">
        <property type="protein sequence ID" value="GIX75117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10748" checksum="DE42A8537FCCF349" modified="2024-11-27" version="1">MARLRAQMRKAAQAPREKFQRTLRRLSRVRGKNKKVPPKPTTTERRSLNEGADPLLRINVDFKRMDLRIKNERKSPDKRLVNEISSPRRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVR5</accession>
    <name>A0AAV4MVR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_666361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002671">
        <property type="protein sequence ID" value="GIX76546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7744" checksum="AF7182BCBCBECFEB" modified="2024-11-27" version="1">MTTCPAEVHGGLESTDAAFLADEAPRSAFCLISPYYPAAWIGSVPDKNVKGRRNSLLVVVRIDTKVVRIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MW01</accession>
    <name>A0AAV4MW01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_422591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002596">
        <property type="protein sequence ID" value="GIX75536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MW01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10091" checksum="4DABD739A5EA7880" modified="2024-11-27" version="1">MRPGRELLLRKGGRSKLFRLLLAVFYRLCWMVDWSGRTTLRTFIRRLAPAHMLTCSALALLPLPHLPLHYLLAFKKFCKRNRVIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXL0</accession>
    <name>A0AAV4MXL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Pde11</name>
        <name evidence="4" type="ORF">CEXT_372411</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020255">
        <property type="protein sequence ID" value="GIX76475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX76475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20874" checksum="EE09BEA5BA6E8925" modified="2024-11-27" version="1">MNSNYTHVLRYQKLGHVLGELETLSLLIACLCHDLDHRGGTQILSHLSPEEYMNIVHVLEEAILATDLNLYYKRKFIFSQMASKGNYNWKQEGDRKLLREMLMTACDIAAITKPWGNTKKGDVEKQLKLEPIDIMNRDKKDKLPLMQVAFIDSICLPVYEAFAIISDKLGPLLEGVKKTEHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3V8</accession>
    <name>A0AAV4N3V8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_547621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020452">
        <property type="protein sequence ID" value="GIX78960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3V8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9337" checksum="7357A3E79643AF89" modified="2024-11-27" version="1">MVRCDSKYMVKKAMSAFLVFLSSCKSSSSTPPSRAVPFEILSTVSGRAQDVYGKVILESGVMSFQCWSGRCVVYLFGEKGIGFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8F6</accession>
    <name>A0AAV4N8F6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pectinesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003091">
        <property type="protein sequence ID" value="GIX81054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8F6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11008" checksum="26ADB8A176C5C086" modified="2024-11-27" version="1">MRAAAANRQFGWGIIVARRGAKRFNVAGGQFFTQTSRESKQENGRLFLNCLINGCLADRGANRWYGNQAAVYGYGCNVSIWQLPYGCGFGDRLFLAFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDW0</accession>
    <name>A0AAV4NDW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_52471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020818">
        <property type="protein sequence ID" value="GIX82876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8497" checksum="1E8B2369445463C7" modified="2024-11-27" version="1">MLLITFKCSDVVLVKDLHQVLSSTHSQPRPPLSPWKAKSLLTADLLRLLYYDSFLLPPLSLRFFLHLLLPPDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE22</accession>
    <name>A0AAV4NE22_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS15m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">28S ribosomal protein S15, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_30111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020696">
        <property type="protein sequence ID" value="GIX81659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052137">
        <property type="entry name" value="uS15_ribosomal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46685">
        <property type="entry name" value="28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46685:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX81659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="266" mass="31737" checksum="D52A18BD879916B8" modified="2024-11-27" version="1">MNNLRLLGSNLRILVIKYDASSIKLQTLPHMYFGVASQFHTSNICSENTETNLPQQPEKKYKKPVDYLPFQWHRRPMFNIFEQSGDKVKENIIDPSTPKPDFELSDELKDADERVKQYFSCQTASRSEAKEALRRQVLKRIQRHPNDFSSLEVKEVVYSRILLPILINRRNSMLNDLRKMDYERYCWLLEELDLYLKPTPLGAKNEKYCKKWDLRRLTKEYCKKMVVDKKAAYHEELKKQQAEFLEEKKQILAWIEEEEKKALNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPD7</accession>
    <name>A0AAV4NPD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003513">
        <property type="protein sequence ID" value="GIX85424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13086" checksum="554EE43616D4DCD4" modified="2024-11-27" version="1">MLKQWETMDWMDRDVQIQRERKDFLLNATWGIGKCTTGATCTPTSKDSTNNGKNSIGVRILFAFERKSFVKLIRIEHVYVLQCILLYFEQTMSATSSVASSNLELMIKKSFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ50</accession>
    <name>A0AAV4NQ50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_788001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021093">
        <property type="protein sequence ID" value="GIX85811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9897" checksum="DA8B773211293052" modified="2024-11-27" version="1">MQSTASLCGIKISQKISNNLGSAEEFLAILGENILLLISAAFWTSDLQIFWVLRIKRIDLCAEKRWVLHIGYYSVGYRKVCTFRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQG2</accession>
    <name>A0AAV4NQG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_176271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021159">
        <property type="protein sequence ID" value="GIX86648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043573709" evidence="1">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7991" checksum="752631846335A375" modified="2024-11-27" version="1">MGPVDGTEWLLWCFLGLAKLGCEDDRQLDAARLYMKAIVHEERTSFKIIGGCTLHTSPSTRDCCNGWSSVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NW86</accession>
    <name>A0AAV4NW86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein argonaute-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AGO3</name>
        <name evidence="5" type="ORF">CEXT_426261</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021224">
        <property type="protein sequence ID" value="GIX87312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NW86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034587">
        <property type="term" value="P:piRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="3">
        <location>
            <begin position="438"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="4">
        <location>
            <begin position="722"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX87312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1075" mass="120269" checksum="A728DB64750D00D3" modified="2024-11-27" version="1">MPPKGKGRGRGGPRQPAQGGQQEQPGHPGGQQQQPDRQQQQPGRPGGQQQQPGGQHQQPGRPGGQQQQPGGQQQQPGGQQQQPGRPGGQQQQPFQGRGDVPPQRQQQLPPGFPGTGQQLPPGFPVRGQQPPSGQPVPTGLSHPTPALEQEKSPPKAQAKPKPQTISPADVGIELRHKKLIEPALPVKPTPGKLGRPIKLITNCVTLQAPSGFVYHYDVEIISHGHSVTTKQPPPKPSAAAEKDEADKDKDKRSKKYRCLSTKKNREIVNLMVETNKMFKGIFPAYDGMKNMYTKRPLGIQTELKCNVVIEDSDNPGNPDDPRGRRTETFEVIIKPVLKSDTYDCAISLDPLHALFDGKVSSVPQEAVMALETILRHGPCKRFTPVGRSFFFPPHPQDIHPLGGGLEIWFGYHQSLRLGQWKPLVNIDLTATGFYQKGSVIDYIAEFLNIRDVRQIYEKGLRDSDIARLRKELKGIRIAVTHLRYRRKYRIVNVSRESANKLEFTSENSDGKTVKQTIAKYFETTYKRLQFPHLPCLQVNPEKKRIFIPLEVCEIEEGQHCKKKLDEKQTAEMIKFTAKPPKQRFDKVRESLKTANFNQDPCVREFGMKVSTEPLALEGRVIEAPNVRYHQEQKIKPRDGSWDMRGQKYFKGAEIERWVLLSFANPRFCGMPKLENFASLLCKIASEQGIRIRQPENIEVIDNRRQSVRSVLINVKKQYDANLAVVVVPAMNKSVYGEVKQAAETVLGLATQCIKEESVVKKCSPPLVSNLCQKINAKTGGINNSLTPGETPPLLRKPIIIIGADVTHPGPSHEIKPSIAACVGSMDSHPSRYAVTISAQTNVNEKKEAIEIILNLKEMVLELLKAFYRNTRGLKPEKIIFYRDGVSEGQFHQVRRHEVKCIRDACRTLGQDYQPGITFIVVQKRHHVRFMPQDDRSGAGKMRNVPPGTTVDNTVVHPLNFDFFLCSHFGLQGTSRPCHYTVIEDDNDFTADDLQKLTYYLCHTYVRCTKSISSPAPVQYAHLAAFRARQHLLTATDESSSASTTSSGSSTFKDLPEEVFKAIKVLDAMKGTMYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXZ2</accession>
    <name>A0AAV4NXZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_589731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021446">
        <property type="protein sequence ID" value="GIX89679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9170" checksum="C608C6AF8DD84B1E" modified="2024-11-27" version="1">MSVTVYLRCTLDEAENASHLLLLWLMNLGQQEPQMTLSPCHHSSQGKINLTCRARELYCGVIPVNLVDSISQVIQWVKRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4L4</accession>
    <name>A0AAV4P4L4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_26252_1</name>
        <name evidence="2" type="ORF">CEXT_780421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021663">
        <property type="protein sequence ID" value="GIX92167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4L4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034451">
        <property type="term" value="C:centriolar satellite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038929">
        <property type="entry name" value="CCDC13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31935">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31935:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="376" mass="44591" checksum="154825AA85912B61" modified="2024-11-27" version="1">MPKDSTDNNGRLRCDACDYQKLKKLENNPDVRELRDKIEQMNIRLSECRTENQMLKRSLYLAKQMVYKEVGETSGDFKTLLKHGEESGFRVERKTRTENVLVLRKKVQDLQDYLKKLEGQEPDRCKAKKTPSEEFVKKRIPEERKAYWRMELERRLARENAEKEITPIVKECSELRKKVATEKAQFRDLSNELNLLRAEYQSQVLKSEEDMGLVQSFETLQTQLQDTLKDRAEIREELAGYRERNRRLEGEISTTKEELQMLYNKAKDNNILIDSLTSKHKQIQEAIEAEKSIVRQNVDRYKNELLDMRENYEEDLKLLDTLQKITYERNSFIDKLNEDIIEGIEIVVEEPEVIEKPPEIVPVEESKPRLLKHPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAX7</accession>
    <name>A0AAV4PAX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_19051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004198">
        <property type="protein sequence ID" value="GIX93125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13384" checksum="67589BCC138640FE" modified="2024-11-27" version="1">MTLFPTPFRIHTLTGGVFGGEVVRAQLRYHYAIGGVYPIPHPDPSIWRGAGVILVPPFQAVFTLDSSRLIAFNISLFIHHCPLHTVPTKPKGEVGHVTHPLHPSFEKISEGADLFRSYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDX6</accession>
    <name>A0AAV4PDX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_331651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004494">
        <property type="protein sequence ID" value="GIX95326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10544" checksum="29CDA2B5BABDF2E0" modified="2024-11-27" version="1">MIFGEGRKTDLLIPSPSSFIGSKSIVVYHRDNPIPCTSFWAALLTDNPFQISLPCVSHHSIRDLGRGVPEKKTVNGFRICTAGTKFRSPLEEIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWS2</accession>
    <name>A0AAV4PWS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein shifted</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">shf</name>
        <name evidence="10" type="ORF">CEXT_557961</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005223">
        <property type="protein sequence ID" value="GIY00771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2170">
        <property type="entry name" value="Wnt, WIF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050969">
        <property type="entry name" value="Dev_Signal_Modulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003306">
        <property type="entry name" value="WIF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038677">
        <property type="entry name" value="WIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949">
        <property type="entry name" value="EGF-LIKE-DOMAIN, MULTIPLE 7, 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949:SF32">
        <property type="entry name" value="WNT INHIBITORY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25024">
        <property type="entry name" value="EGF_TEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02019">
        <property type="entry name" value="WIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00469">
        <property type="entry name" value="WIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50814">
        <property type="entry name" value="WIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="WIF" evidence="9">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="128"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="192"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY00771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="34855" checksum="1266848D011CA246" modified="2024-11-27" version="1">MEIYAILDGVVLPYILEPNFEKYLPIIPAEVVSVNFTWKAGDQKYFYDFDQLKSYNETILSDPLISIDTKGKVPRKSKIFQVILPCHRNQSGIASFSISLKIENDKGSYLPGTPLRLKLKKQCGDHGPDPECDKKCANGGRCDQHGICQCPKGYMGKYCDSALCYPVCINGGTCVAPGVCACADGYQGPHCEGGMCHEKCLNGGKCIQKDTCECRRGYYGNRCEYSKCHSVPCLNNGRCVGINRCRCVNGFTGNQCESAVTQPAEITKRERCKKKCNHGKCRKKKCICEKGWFGGKCNKRQPKRKRQKKLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PYQ9</accession>
    <name>A0AAV4PYQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_339721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005164">
        <property type="protein sequence ID" value="GIY00303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PYQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17388" checksum="19D6010B383F0752" modified="2024-11-27" version="1">MIELEDLSMNDKLEDLSMNDKLEDLSMNDKLEDLSMNDKLEDLSMNDERFIVKITAAATPTEQIEEIETFICDYQPDILMNQCFNKPSLHVSHINLGDNKFAFAVLLVSSIQASWYLTAQTSGSQILDPPIADLCPFMWQSTLLRRFSGRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5N4</accession>
    <name>A0AAV4Q5N4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_137116_1</name>
        <name evidence="5" type="ORF">CEXT_64111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005784">
        <property type="protein sequence ID" value="GIY04993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5N4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050666">
        <property type="entry name" value="ESRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13976">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="43"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="164"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY04993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="239" mass="26612" checksum="1C087B938C62C831" modified="2024-11-27" version="1">MLSSKLRNILRISNIAPRTLSIFRNTNDNTYPVRTFCDKSSHIVQMRGLDCETSEEDVIEFFKPLGITPKAVRLKSDGSGRVAGICEVEFATYADAVVALRKKNAFMGNRFVRLALKSLGTFSKGSHPLESDGSVDNQKSTSQSASSNLNMASNVQSLHQKGYIVKMKNAPKRITDLSIYEFFWLVGASAVSTKALYNESGIRSGEFEVQFSTYNEALRAMIKNNTYLRSNLVELSLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA38</accession>
    <name>A0AAV4QA38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA polymerase delta subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pold2</name>
        <name evidence="5" type="ORF">CEXT_350781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005890">
        <property type="protein sequence ID" value="GIY05881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="4">
        <location>
            <begin position="39"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="3">
        <location>
            <begin position="207"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY05881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="399" mass="45486" checksum="8749180E7FFAB064" modified="2024-11-27" version="1">MIPINQSFCNDTSTYVRPSSSYICKCNKFLVQDLTFERQYATLYTSRLRISTELLQRQINKKWGPSANVKKLCDITGDEKVVVIGTIFKHMKLHPSILKEISDEHHMVPEPVTEEYTKEDDFLILEDDLQRVVLCGNIDPQFNVTGVTVAVLGYTEESGKFFVEEYCYSFVADPEIIYSPPIDKYVVLVSGFRFEWQYIGKEKKRSSNKSKLLARKVKSETAESMAILDRLISELVSSVSVDIMPGEFDPANHLLPQQPLHPAMFPKSSKYATFNVVTNPYEAVIDGIRFLGSSGQNVKNIKAFSRITESLDVMQKMLDWGHMSPTAPDSLNCYPFLNEDPFIISQYPHVYFCGNSPKMGYRFSDNKSVMMIAIPEFQKTNCVLLLNLRTLEVQPIIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAD4</accession>
    <name>A0AAV4QAD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_155881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005923">
        <property type="protein sequence ID" value="GIY06070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11961" checksum="173DC2284C35CB64" modified="2024-11-27" version="1">MRVAGSSPLDVAASVFVRSRSQRGGVEPIDRTVAFSILFRYSKGHAHRQSVKETTPTYRERGPLARTALCSSSERGRGKKEGQHSLVKERLLFQGLGSLTNDSDLMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBB8</accession>
    <name>A0AAV4QBB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_607921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005838">
        <property type="protein sequence ID" value="GIY05396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17738" checksum="0E324AE23CAEB017" modified="2024-11-27" version="1">MPLSSAKSIFLISFYLAFPPTKIPINLQANQTAKPLILKTNLDFVNKKRESFTIHNSKILRTQNVSFLSTLSEIRLLRILYGSSLRIILLLRGNSLSLCEVHFGALGRFKEISRFYRETWVFEFGEDATSGGGMNPFPDGVVSVLLQMHLVTMKNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QC53</accession>
    <name>A0AAV4QC53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_761351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006031">
        <property type="protein sequence ID" value="GIY07005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QC53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17854" checksum="7996B1BCBD95C802" modified="2024-11-27" version="1">MCCTKSSPSGALGLLPEVLRLVMTQTTQRTAIRTMVELTTGTLKKKANRKNIERNSVPKEPEQERAVPKEPEIAIKKDSKLLQCSGTVLHISESGLDHSNLLLGLHSHLSVISYTSSSEEPYITHLRNASRNTKESHNKSVNRRRSVNVVLTSPAYHLVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGY5</accession>
    <name>A0AAV4QGY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_526811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006130">
        <property type="protein sequence ID" value="GIY07611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10392" checksum="819CE140F750B1E0" modified="2024-11-27" version="1">MIRNPVYMNTDNHRRYLPLASTTKCMDVFIAAPIAPIGGALIDIPNNHRCVGERKQIRHKYPFATPIFMAVVAEVMDCYSQKRRILTLWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHG9</accession>
    <name>A0AAV4QHG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_663751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006334">
        <property type="protein sequence ID" value="GIY09148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10779" checksum="59933688C60BA6A4" modified="2024-11-27" version="1">MCFLFKVQHGSTFVLPVTYHGIVWNHARGTSATIGRKSFMSTDTEMESFNEGGLGMTGCGSGGFVRHKSKLAHEKRARARLPVSNFVSGTRVWFRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSA0</accession>
    <name>A0AAV4QSA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_530451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006594">
        <property type="protein sequence ID" value="GIY11027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16072" checksum="7D75D25CF8CA171F" modified="2024-11-27" version="1">MIPLPHKVDVCVCLQESICCERNSTLPKVLLEFPLKALKFDRVTSQKLRYKLPENNMTHNLDMATLCSVMMNRLSTVLNHGKVTDPSFYASCIKVNSKGVFDLIQNPNTIEMNLKVLDIPNKVIISYHISILYIDNGYVNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYT8</accession>
    <name>A0AAV4QYT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_713181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006908">
        <property type="protein sequence ID" value="GIY13241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="295" mass="33476" checksum="42AEBD9EC18B6558" modified="2024-11-27" version="1">MRGHDKLHIRKQTVDWTSTAYNATLDIHHHHLPCQFVRQNSMDRAHTPALDSRLLVDRQYEVLFFPRGLECIEASDDRKHYHIGHMLTRTDSGLVARPESFAAIFSRRFSNRRLRSASQIFCFISGFCLLRQALSSLFLPASSGGSLAQLISLYLLAALMDKSVDVKARHDRIACMQKFAQGYPKQKGYPLPLAVHLCGFYADSSDFGRKQVDPQNPAPKVTFSKDLNTNKTCSYSLYKPGVKEPPAIEYVPAEAWTIGMCSVEKAKLSYANSKRMFEVRLESSTFHPLKPLMPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0M9</accession>
    <name>A0AAV4R0M9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_567711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007186">
        <property type="protein sequence ID" value="GIY15052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="15223" checksum="ADEB1FE1FECA2F98" modified="2024-11-27" version="1">MQFWRLGLLPVILRRGNHFLVSTCFPPLHARQAENTPCGENKGSSKTDGQSITCSSTSLMCFPLFLHGPFFFLLFFSLPFVWVRPCPVDAVRKVVLRPFRFPPTSIKPSAKFVTLKGSSSILNNRKYRFSGQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0P4</accession>
    <name>A0AAV4R0P4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_658361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007200">
        <property type="protein sequence ID" value="GIY15124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0P4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9324" checksum="2BFC27819C262CB0" modified="2024-11-27" version="1">MKPNLLLASLSGVEGETKTNANYDTSSFGTYPVFTLSGVKATDCPYVCSRVFTFMSQAGISGLFPVLFAFGFLLAEMHFHSSSLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4L7</accession>
    <name>A0AAV4R4L7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-ribitol-5-phosphate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ISPD_1</name>
        <name evidence="4" type="ORF">CEXT_784521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007218">
        <property type="protein sequence ID" value="GIY15266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047349">
        <property type="term" value="F:D-ribitol-5-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43015">
        <property type="entry name" value="D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43015:SF1">
        <property type="entry name" value="D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY15266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="426" mass="48056" checksum="ABB6413FC447ADF5" modified="2024-11-27" version="1">MNLPILNHFNYGKQSMKKTTGYGYTRRISEKALANGDIKSHFICHRSGVHKSGSTGQRKLKKIGSNKIGTTCPSTLEVTRMSSGKVKVVFYKTHIGHKADPEHAVVHKQKGFKRLESICFGVCNSSYCRKRLPFIQKVVVLAPSGSLHKMLNVLRENCSLQGQKVMVAEGAETRHESIKSALKILQTCCETQPEVVIVHDGTRPFLPSDEIMFNLIMASKEHGASGFTYPLNAVMLEVLSKAYESISTNDLECGTECLKIVRDYAGIKAKVVAFNFSLVESYSPKGYIFDCSISERKSVCCYHHCPCCWNFHTRTFDLYQNFVFIYEHNNPYDIIENMNICNGKKLTFLCTVVHIFTKDFDDTINFVEFQKHASTTGRKLTKSNIVSYIFAWSQTDSTEKVDHSSETVRSLLFDSNVNLSGTIFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6A6</accession>
    <name>A0AAV4R6A6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_801801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007446">
        <property type="protein sequence ID" value="GIY16990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6A6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11735" checksum="6B6DF79062B16836" modified="2024-11-27" version="1">MKTRYFLVHNWASFPPFHTMNTQLTGLEGRLLWWHIDMPYVKLMPRGRVMKMKEMMGGEVCGAKHLQIMNQTYSKGDRLEEPKGQYRNVIWWKVERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RA29</accession>
    <name>A0AAV4RA29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_349471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007489">
        <property type="protein sequence ID" value="GIY17267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RA29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10795" checksum="D1BC82A5536875A9" modified="2024-11-27" version="1">MNSFKIREAERGLKQRNDISPGIAFTGAPFIARHKLFYFQGNMNSVCNLAGIPDAFYRRQIANNFCPRLNFYRFRFRSEICACAKFECGRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RED6</accession>
    <name>A0AAV4RED6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_681181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007703">
        <property type="protein sequence ID" value="GIY18969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RED6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16929" checksum="7311466601354CE0" modified="2024-11-27" version="1">MANYKECCSDLSNIRCEQFLDFMKQQHQRRARFFSVDFSAVFNFKLEWNKNSGFVYCEDMDPSLAHDVRSMKHTADSSVAGKSVFSFHKFEDFLNFVRFLWCLTDNCIDPADVQILKASVDIGSFGNKIVEIFSEKELFEFPELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RH44</accession>
    <name>A0AAV4RH44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_565061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008000">
        <property type="protein sequence ID" value="GIY21319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RH44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9899" checksum="B412EF98C6A7E2CC" modified="2024-11-27" version="1">MHIRVPCRRSRRSTSNLHSGEPLPPPQLSQAEPEADHPGPALNTPPGSPCMNPPYWKSRLTTIKNSFLGSPRFHRRNCKVISSIIFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNJ4</accession>
    <name>A0AAV4RNJ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_230811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008116">
        <property type="protein sequence ID" value="GIY22209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="50"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11355" checksum="0DA0C43D3FB9B747" modified="2024-11-27" version="1">MKLRWYGEKKSSLNINLQVCIVPIAIESVFKDSNSLSKDFRLLYEDPLLSDMKLKTETKTFDVLAAVLSARSEVFKIMFNIEMTEKLNRNVYISDVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWK9</accession>
    <name>A0AAV4RWK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_190661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008573">
        <property type="protein sequence ID" value="GIY25762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10982" checksum="19F6139E8099F594" modified="2024-11-27" version="1">METGDITKSAFANEFAYFRYRCSMCHRLPWTLLNIPSFWTVPLNSATVAQDNGMRCRLPDEVSPDGVLPGEVSSSRCVDYQMRYHLEMRCGLPDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0G2</accession>
    <name>A0AAV4S0G2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sorting nexin-27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SNX27</name>
        <name evidence="1" type="ORF">CEXT_807241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008682">
        <property type="protein sequence ID" value="GIY26439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0G2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12431">
        <property type="entry name" value="SORTING NEXIN 17 AND 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12431:SF19">
        <property type="entry name" value="SORTING NEXIN-27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11473" checksum="FDFD37BE4FCD0560" modified="2024-11-27" version="1">MQYLKLARQLDGYGEISFPHCSCDARKEGHVSQIIDFNWDTVKEWELDDEGMSFSFKYAPPDKKPRYVKIFTPYYVFLYDCFERIQEERKWNING</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1V5</accession>
    <name>A0AAV4S1V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_813911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008802">
        <property type="protein sequence ID" value="GIY27314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9823" checksum="C91D8883F5358977" modified="2024-11-27" version="1">MLILEKGHPDKNILVLEKKECVDQETMILEEQYLDKDIPILKKGRLDKDILVVGKECLGKGILNPETGGIDKAREAKQIFQHAKVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3J3</accession>
    <name>A0AAV4S3J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_766981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008871">
        <property type="protein sequence ID" value="GIY27899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="19066" checksum="653396DD52A5CC3A" modified="2024-11-27" version="1">MDTNSDSVVHRTSMINDENLSYGELTQKNRHRLFPHLHGKKNPTPSPSLPRNCTSLEEFTEMKFETRTQQKTVICPLFHKCKEWNRCTFAILSRYSEVQLAMDTNSNSAVRRTSMINDENVILRRTHTKRIAIVCSPTLKEKEHRPPHPPCLEIAPRWKNLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7L1</accession>
    <name>A0AAV4S7L1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_618881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008945">
        <property type="protein sequence ID" value="GIY28445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7L1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9891" checksum="A387BF113CABE74D" modified="2024-11-27" version="1">MNGGGTLTGLLSQGHGQRLVFGKMTDEFNFQAETRVPMAATISHPAHCSCSPLATEKAEDGQRCGRSVPRNFSEVKSQRVPCYNGQITKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLL8</accession>
    <name>A0AAV4SLL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_546281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009642">
        <property type="protein sequence ID" value="GIY33462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13352" checksum="DCCC79A3184F321E" modified="2024-11-27" version="1">MFNFQWRVASPSRPETTLYVNATMLELTLFCSQPMLNRMSFNFKMVFEVIAGIGCALCAFFVFLTFFILLVLWRKISGAITALKIQVCIALIGAYATILKALHESLTKVCIILIKTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNP8</accession>
    <name>A0AAV4SNP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_615971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009712">
        <property type="protein sequence ID" value="GIY33992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="24695" checksum="A0FF3751BE1BE32D" modified="2024-11-27" version="1">MREMNLHQKKKTTKFTCRNPLPPLFNEGIISNLTLKNILALYPPPFPCEEREEHVYREKKDGLGFLEAGARSQVVRGRFLSGPRISPVYDQASSAVPRILSGVGCLLEGGNRPLHPPPILSIRVGGGRVEEVTPTPFQNNPSLSVVNQCQTTAQREIKGDTSIKERKQQEEKKGEEWNKKRRRKNSARGGMEAEKNLVPTGERHPRKRTRRQGRKGDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STA1</accession>
    <name>A0AAV4STA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA pseudouridylate synthase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPUSD2</name>
        <name evidence="3" type="ORF">CEXT_110371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010062">
        <property type="protein sequence ID" value="GIY36541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="161"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY36541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="28123" checksum="1335B99C4B112BA0" modified="2024-11-27" version="1">MISRFKKSSKICSLFYRNYEISSSISPGVFTSVLNENDEDLENLRTDDTITEIKNTFDIKRWPYYIENGLQKVYPYNFKHSTYCKGRWVNRTLIDVYSNDFSLFPKEEIERRISTGILKVNGKIVNYDYKLKHSDVLSSEVHRHELPILAWAIEVIFEDDDVLVINKPASMPVHPCGLYRYNSAIFVAEHQLKLKILHVIHRLDRLTSGVIIFAKNRKKSQELHEDMKLGSIKKKNTYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STY7</accession>
    <name>A0AAV4STY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_192691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010181">
        <property type="protein sequence ID" value="GIY37534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10236" checksum="4DF368411CECC5DE" modified="2024-11-27" version="1">MPGTFLHRPITYPYLVLQERQTKLKSNSLNHTHPNSSLVVWACSLPAFSSSCGVGCVLRVNALRTIIALAHACRKCAFFSHYRSFPTNGSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SU36</accession>
    <name>A0AAV4SU36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009982">
        <property type="protein sequence ID" value="GIY35957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SU36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8709" checksum="FB08D05C91A4D397" modified="2024-11-27" version="1">MQKINTEPVYPVASAFLTRSQTERSIRKRRLKNVLSFRSNPMLSLPAGLCRVAGIKLGDTRALAKFYRQHSESGFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SW07</accession>
    <name>A0AAV4SW07_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NPR1</name>
        <name evidence="15" type="ORF">CEXT_271461</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01010135">
        <property type="protein sequence ID" value="GIY37194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SW07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000004">
        <property type="entry name" value="Guanylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY37194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="21564" checksum="86DC43C644AA645D" modified="2024-11-27" version="1">MNKISIRYVADQLKKGNKVEAESFDCVTIYFSDIVGFTTMSAQSSPLQVSSGLLNDLYTCFDSIIENYDVYKVETIGDAYMVVSGLPIKNGDNHAVEIASMALHLLEAIKKFVIRHRKNDTLMLRIGLHSGAVCAGVVGQKMPRYCLFGDTVNTASRMESTGLPLRIHCSEECKRLLDKLGGYKVEEKRCRFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDA4</accession>
    <name>A0AAV4TDA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_792111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010979">
        <property type="protein sequence ID" value="GIY43461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17006" checksum="F948FCD4D7562DDD" modified="2024-11-27" version="1">MNSPPPTQTRGSLGTGALIVFQDCSSWPCGQLRFSFSTHSFCNSPNLLRKPNSNHQKDVQVLSPFRKQRIYTDEIPLSARNAALSSLPVIRSICSIICCAEIPPARKFVSMNLPPPTQTLRLTWIYGTSANCILGLQLMALLATLMSASKLASAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGF8</accession>
    <name>A0AAV4TGF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_69661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011043">
        <property type="protein sequence ID" value="GIY43850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8588" checksum="299B39DACE1BE58F" modified="2024-11-27" version="1">MQHLCVCLHAEGRCLHTYSSTRRITGNEAIDHCFGQSRYLTPISKSSPSVKILCSVTVAYALNILAVEILGVENKLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TLA2</accession>
    <name>A0AAV4TLA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_781021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011568">
        <property type="protein sequence ID" value="GIY47353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TLA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11947" checksum="F049F33A21F5570A" modified="2024-11-27" version="1">MLSNEGRERGTRGGRGKDTWGWGGGLLFIACVSVLPHNRFLRTLFSLLPVCMTKRRKSALCKTGTQSVAMVTNVIQRRKRRGTWGGREKDTRGGVSPLYRLLVRPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRA0</accession>
    <name>A0AAV4TRA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_776511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011635">
        <property type="protein sequence ID" value="GIY47842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="13549" checksum="60FC0EBDF94BBDB5" modified="2024-11-27" version="1">MAVSLLAAPIASGCFLGAIAPKSPPPTISEGEDFIDPFFFSTLSFQNGTIESYHSHVSLDSTTRFSLSIDWHPNGSSMAGSLLAALYFHQVLLGAIALKSPPPTISEGEDFIAVSYEPVQSKDESSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWU8</accession>
    <name>A0AAV4TWU8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011876">
        <property type="protein sequence ID" value="GIY49747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10752" checksum="0DD29554FC64761F" modified="2024-11-27" version="1">MWLCISYSLQITVKKKIYSPKLVCVHCSVSWRTFNLLVAHRMGGARSAVQNHGATRIMTQNTLLLHLPLAESHLGDRREKEKLFSFPVRPFMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U265</accession>
    <name>A0AAV4U265_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tyrosine-protein phosphatase 10D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Ptp10D</name>
        <name evidence="4" type="ORF">CEXT_101181</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012168">
        <property type="protein sequence ID" value="GIY51840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U265"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050991">
        <property type="entry name" value="ECM_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708:SF2">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708">
        <property type="entry name" value="TENASCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="109"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="202"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="497"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY51840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="509" mass="56839" checksum="7640E745A31C36A0" modified="2024-11-27" version="1">MNENLEALGMYDMCSKYEQTTGDIGIYDVCRGSELKFRIPKEAAASGPGVYRVSYGPSSGFPASNFTVDSSLINQLITISDVLPGTLYTFHLYFSNATLHDKLIWSSDLPTKPERDRDGGKVAEATWDSPKLGGQTGFKLSLVPLSEKDEATARNNYINHLTPFLLRDLTPGASYEVKLFSVFHGQDSSVFVATNFTTKPNTPGRFIVWFRNETTLLVLWQPPYPSGVFDKYRVSISPEDALQSELFVDKERDPPGPAQAAFYGLVPGRNYNISVQTVSDVQISEPTRAQYRTVPLPPVNVTYDPSRLASFLVRCPDEERVVTFDEELEPGQTYEVVVKTVSGNVASWPVTANITTRPLPCENNERHLRARGRNLCEMGASDQQHAGFIQGEVQRHGGLQQRGQLAGGEEHKHQPDVLTSGKELFYQRVRCQQKDLQRTHGRLPAHHKYTSNPFLPVRKALPMTLSFKDLNSLAWRNSSLDFELENLGLKPKKKTHTQSSPNTSGNGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U714</accession>
    <name>A0AAV4U714_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_96781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012370">
        <property type="protein sequence ID" value="GIY53506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U714"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11332" checksum="945960A5E093264D" modified="2024-11-27" version="1">MCWWRCDGGDLTIRTSVILSSGLGDLLVVVLASRPTMDSMEKPSFGLVEFCSSVRWQNGCWSHWHHAGSEVTSHRSKIECYTTVSRTLFLNIDWIRRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U761</accession>
    <name>A0AAV4U761_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_670721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012388">
        <property type="protein sequence ID" value="GIY53648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U761"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15055" checksum="5B80AD83736DA667" modified="2024-11-27" version="1">MVDQKSRERNAKGMGEKKKKKTEMPFPTKHKMMGIISKRLPKAVLAETDLQCGMIYNRLNCLVKGEILIPSTKGGMGVRGGEKYNIFNSTTVRLSFSEEKATSHTSKSTAEITTHPSIACKVSSIFLTIVPIPIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8I6</accession>
    <name>A0AAV4U8I6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_627561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012441">
        <property type="protein sequence ID" value="GIY53955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8I6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11285" checksum="53BECEE787CC0408" modified="2024-11-27" version="1">MVHALSALRSSDGSVPGQTRQGFSSACQSASLGKCAQYGISMEGKTRVKDEGRRGNKIDLTSRVGSPEQTFIAGEDSHNLKVEELDFSLSLEGNDGFWDLLKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9B6</accession>
    <name>A0AAV4U9B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_502231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012482">
        <property type="protein sequence ID" value="GIY54210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10699" checksum="4A0CDE8B02FC93A8" modified="2024-11-27" version="1">MTPQKKKKEPHKAAGICVTKRETKPPWKKFHLIPPASNPKANRERGLIMSPERRSKRTFVICSKHQDTRSTVDNSFECCLSRTFLFEDAIPSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UGA2</accession>
    <name>A0AAV4UGA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_656431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012820">
        <property type="protein sequence ID" value="GIY56861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UGA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13954" checksum="B83DED90551C08C0" modified="2024-11-27" version="1">MLTLGPIEICRIRNQCQQVANCPTSASSFPVLLHRLCGSVTRSCNDGLSNRKAWSLQPSMHNPLEGTPSLWNSFFFFSWYSFSSSSSCCCATVNYENWAATLLGHACKRAKATCTGKGRRVYFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJC0</accession>
    <name>A0AAV4UJC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_203773_1</name>
        <name evidence="2" type="ORF">CEXT_743151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012963">
        <property type="protein sequence ID" value="GIY57809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043898862" evidence="1">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7792" checksum="EE752E5665B3AF26" modified="2024-11-27" version="1">MYAVIALVLVSLAFVEVNSVCEPGKYLVTMEKKELIDVVDCVSKSKDPLLCSKFAACERLMSPRVKKQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMM5</accession>
    <name>A0AAV4UMM5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4158 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_678501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013141">
        <property type="protein sequence ID" value="GIY58992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="14369" checksum="3A75DED0A4117A70" modified="2024-11-27" version="1">MPFKKRGTFLLTDPTIDLGRESFERGPEKRALLSTLFILGVTYFRKRSHALALSELHSDIWKEINSVVDTFYRQVKLPTDRIISKLLGRHGDSDSLRYVSFSNNRQHESWTVESMPGKSFHEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URC7</accession>
    <name>A0AAV4URC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoenolpyruvate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ppsA_4</name>
        <name evidence="3" type="ORF">CEXT_157971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013312">
        <property type="protein sequence ID" value="GIY60328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051549">
        <property type="entry name" value="PEP_Utilizing_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615:SF1">
        <property type="entry name" value="PPDK_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="2">
        <location>
            <begin position="108"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY60328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="445" mass="50550" checksum="CC512DE3E75D0EDD" modified="2024-11-27" version="1">MSQHRHKGAEYTLSLSVPLTIQFPEEASHLKKISGGKGSSLGKLTQLSQKEKKHSLFQKGVVVTTSAYNEFLSMEICDAVKHLEDVAYGNEAGDLKETCKRNGQVLNSPMAVVIQDMVDCKVSGVLFTCDPITHNPSVITITANYGLGESGGTATEDVDDNLRNEYCLKIQTVERLGKIAFECRPVTKTAAKTDHEIKHEFDAPLRCENEYFTVANIGEILPGATSTLGIDLVMKYYSVYFRDLFFYDLGFEKVKKKINNYSLDFLKLKSAEETFTALINSCSDFDEDISCQIVKDLGSERFRCFSVEEAEYWLQTTKTISGHHFREFLKRHGHRCLKEFDVRSVTWGMNSKLLVKLLQNLAVSTKKEIKKESDSIDKIFSQLRISLNFTSRFILPLCRKAVRVREAGKSLTIKSFDHWRKGYRRLGKLMVSEGRLPDQDLIFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT87</accession>
    <name>A0AAV4UT87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_447501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013365">
        <property type="protein sequence ID" value="GIY60709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7753" checksum="8492A6A77BC673BA" modified="2024-11-27" version="1">MTSGGERGGHILLPLSIAVPESAIHTGIFCLASFCEVLNQASKEMTLEHISSVNKLQSFEEAKTSSCLENCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXM4</accession>
    <name>A0AAV4UXM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_576381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013591">
        <property type="protein sequence ID" value="GIY62194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22955:SF66">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22955">
        <property type="entry name" value="RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="16107" checksum="EC165B16C1D03C82" modified="2024-11-27" version="1">MAKYVVTALSLKEVPAYYWTDATVALCWIQREENWGVFVNNRVKDIRSLSKKEYWRHIPGKLNPADIASRGCTLQHLSQYGWWDGPEFLKASSEAWPKSEFSAKRRINCSRDEKENDCRLKCKNREAQVVRAFLQFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYI1</accession>
    <name>A0AAV4UYI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_449361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013625">
        <property type="protein sequence ID" value="GIY62509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9599" checksum="6E91FF5B9F473801" modified="2024-11-27" version="1">MRRIHISAFGIIHPFKPPPVPCLRGRILMIKRPRINKGAEPERRNYLATSSPSGRCFTSLKTAMMNFNQTPQPFKSNCDVLRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8Z0</accession>
    <name>A0AAV4V8Z0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_351731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014122">
        <property type="protein sequence ID" value="GIY66493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9117" checksum="D8CDE447406AA51C" modified="2024-11-27" version="1">MRKVTPSPDRTEAPEKILLFLPWRPSTLSPLPGGRAKNSCSRPHLRSPRPGHLLPAHLPHFPPWWEGGFSLSREQCRENC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDY5</accession>
    <name>A0AAV4VDY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_662501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014287">
        <property type="protein sequence ID" value="GIY67834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11382" checksum="C39A80B1874F9E73" modified="2024-11-27" version="1">MKCLLPQPVMSPPPFSYHIIATSQGIVKYSAENEPRCCCNLCSGVAKTGGNGAQSAFFYGDISAIYTEQYMDTMRNHSDSLMPSEMSTDLEDSANKVMWQKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGG2</accession>
    <name>A0AAV4VGG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_719951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014415">
        <property type="protein sequence ID" value="GIY68643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9445" checksum="34060B4CF60E411D" modified="2024-11-27" version="1">MTSVESVLSLDAHFRSLPLKLSGTTSILATASPFKMRAKIYWPVSQRNRGWAILERSIPLHPSSSSGTHPHPRLLSPRGSARNPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VIS2</accession>
    <name>A0AAV4VIS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proteasome subunit beta type-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSMB1</name>
        <name evidence="6" type="ORF">CEXT_215771</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014579">
        <property type="protein sequence ID" value="GIY69734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VIS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000027">
        <property type="entry name" value="Proteasome subunit beta type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY69734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="228" mass="25467" checksum="EB4B810BF797E110" modified="2024-11-27" version="1">MNAHCNELEMFSKPKQLAFSPYESNEGSIVAIGGEDYAIIASDTRLSTGYSIYSRNQPKLFKLSNKTVLGSAGCWCDVLTLTKIFEAKMKMYLHEHNKEMSTPAVSQLLSTLLYYKRFFPYYASNVIAGLDEEGRIYSYDSIGSKGQEKYIAAGSSSHLLQPLLDNQAAFKNMEGPRPPPLSLDKAILLVQDVFTSAAERDIYTGDSVLMNVITKEGIKEISFDLRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W253</accession>
    <name>A0AAV4W253_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_96001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015536">
        <property type="protein sequence ID" value="GIY76806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W253"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15026" checksum="6C3DEC2960C962AD" modified="2024-11-27" version="1">MIPTARHIFTSIAIITLKQNVFLSPSHCFSTQIQLFRTKRGRAKQTMQFRGERGGGGGGTRGVDVSSPSVSRFVPTRADYDAISQGRGGIDKHFVLVCGSALAPVDKQFASLPRKIFFDSQECRGFQNEEGIRGTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6M7</accession>
    <name>A0AAV4W6M7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ionotropic glutamate receptor L-glutamate and glycine-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_233921</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015644">
        <property type="protein sequence ID" value="GIY77579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="11">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY77579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9723" checksum="182A43F55661D540" modified="2024-11-27" version="1">MGFLYELMVPEDGLFGNRLEDGNWTGVVGLLQRNEADMAFSYLSAKSYERYLILDFSTTYSSQVQTFVTEMPPLVPKTTVSCILLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W828</accession>
    <name>A0AAV4W828_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015750">
        <property type="protein sequence ID" value="GIY78369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W828"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9565" checksum="C7090EF4C0E4EF75" modified="2024-11-27" version="1">MQGILLPIFNNQSLTENPSFKERKKIKEKKIYLRVFKTDKKDKHEEEKLLCTSRFTRTHNYYPSLEMLLNAHESENDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCP7</accession>
    <name>A0AAV4WCP7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_805591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016016">
        <property type="protein sequence ID" value="GIY80527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17847" checksum="B8885582FC622262" modified="2024-11-27" version="1">MGERNTNNSAPTFSSSVLELFKTLSVFAHDETLIFPVLLQAIRSALPLFAPSIMMKKKQSPFSSIIALTLPIIKFNTNNCNNNLQSLRFGFWNASGLNQRLEEVKEFISDQNLDILMIQETFLRPGLNPSIQITPFIENDRDNTTTYRTYGGYLYLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIB0</accession>
    <name>A0AAV4WIB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_255891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016261">
        <property type="protein sequence ID" value="GIY82581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="20403" checksum="26BC8FA822CA72CC" modified="2024-11-27" version="1">MRRRVDVSPPPQLMVDPVPASPSPPPRRAGDSSPSAISTRSGDSYSGRYSPSLPSSRSSPARDESPPAGTAIQRNPASPSPRASPSPPASPPPYAGRTTRSGRYYPYRRPASSAAVPPPTTAAVPPPTTAAVPPPTTAPRPLPTPGPVTRCKTGSLPLRTSPSTSPESLATVRCRDQRPLLMAKCCPRALRSASTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIP3</accession>
    <name>A0AAV4WIP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_368301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016175">
        <property type="protein sequence ID" value="GIY81856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10091" checksum="83938ABABA8AC9B5" modified="2024-11-27" version="1">MLTPSSAAAWASYRNRFSRPQKTNGSNNFRYGVPGEKPNARIQRRKSGVKNKSPVHERTRGGGGGPPQETINSGVKTEKKLPYGKTAGNLPGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLG3</accession>
    <name>A0AAV4WLG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_50620_1</name>
        <name evidence="1" type="ORF">CEXT_198841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016346">
        <property type="protein sequence ID" value="GIY83158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="314" mass="34888" checksum="0B40D5471D797B78" modified="2024-11-27" version="1">MVTFSDEECVVGLKTLGVSVLNDGKSILAISEGHDEILRFDTCSGHVANRIFPGENRHLDCLLVSENGEVCVCGDAVQKPYPLYAWNVETGVLLRHFANPHHEFLVRLSKLNDDGRLLLATAKELLDSTPTFLVVYDTTTGSTVWQVRPESTSQPSLCASKLTERSSQPKGGLYALNIHTGEERFVITSTSNRIDRIQTAMNKTFLTWDSSSQCRCLRVWDMVTEYLIDKKFSSTLIKVCSVNAMPHKHVKYEIYAKIALTQEALSRLSLLITTSTTVFFSGDGSSIALLLCDKEEPALLSLKGTEHVQEVLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMZ3</accession>
    <name>A0AAV4WMZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spider silk-constituting element SpiCE-CMa5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SpiCE-CMa5A1</name>
        <name evidence="5" type="ORF">CEXT_900341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016368">
        <property type="protein sequence ID" value="GIY83330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19941">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036084">
        <property type="entry name" value="Ser_inhib-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051368">
        <property type="entry name" value="SerProtInhib-TIL_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002919">
        <property type="entry name" value="TIL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23259:SF70">
        <property type="entry name" value="ACCESSORY GLAND PROTEIN ACP62F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23259">
        <property type="entry name" value="RIDDLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01826">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57567">
        <property type="entry name" value="Serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043786342" evidence="3">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="TIL" evidence="4">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY83330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8426" checksum="191BD327B63E5BEF" modified="2024-11-27" version="1">MKALFLVCIVSLALCQTINACDSNQHHVDCGTSCPLTCANYKNPPRFCTADCFFGCACNDGYVKKTDKHGACVKPSEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPL1</accession>
    <name>A0AAV4WPL1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_54591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016391">
        <property type="protein sequence ID" value="GIY83478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27186" checksum="B908BA3EAE479920" modified="2024-11-27" version="1">MLQFEARSTSKGPNQRTALLHIKGGYHFSHYCTRVQGTGSQPTEQREQEAYASVLCTVQQFLTAEEFYSVTDLLGTRISVERYQGRNRVPQCYRCQGFFHSSVACPLPKSTPRYDHTDTANILDFALFKNIPYTTSTAVLNELNSDHLPVLIDIELNRPPHTAPQDFKTNWHDYNFHLQNTNLNTFNIDTKEKADMAIKNFTTAMINAFNKKLRHKTDCTLILNSHPRLKVKLNSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTF1</accession>
    <name>A0AAV4WTF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin-K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CCNK</name>
        <name evidence="3" type="ORF">CEXT_756241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016689">
        <property type="protein sequence ID" value="GIY85766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY85766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10624" checksum="15C440EF124BF33A" modified="2024-11-27" version="1">MTVLMPSWYYEKKDIKHSPSVLDGINFERESRYRREGARFIINVGTKMGLRYDTMATGVVYFHRFYMFHSFKTFPRYVTACCCLFLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WU49</accession>
    <name>A0AAV4WU49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_247641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016622">
        <property type="protein sequence ID" value="GIY85174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WU49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="17008" checksum="A87A7110C5DD2BEE" modified="2024-11-27" version="1">MSSQLNTLTRAIQENAFCAREMELPCLLTVARFRELRLMKIYWQSLPITVFGMPAMHGLRTRVGGIDFFLFFFSPLFHFPFELLGRCWLEQMPGCNLAMVQKNEGLSCEKLKCLRGWGKWVQRVSTDTTQAALSMLGSLISHERISNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1I6</accession>
    <name>A0AAV4X1I6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_144801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016995">
        <property type="protein sequence ID" value="GIY87931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1I6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11381" checksum="93B2D4A295FC73F9" modified="2024-11-27" version="1">MNSGVTDQNKTHNKIMKIRQMKRGGKDGKERRKKKKKRKILDAMKGSSQNWGGRGGSRRRSLLHPPFHFPGSTFVSISDRAEKYRRQRSKKRRWMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEJ9</accession>
    <name>A0AAV4XEJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cell division cycle 5-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CDC5L_0</name>
        <name evidence="1" type="ORF">CEXT_200611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000261">
        <property type="protein sequence ID" value="GIY93356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12853" checksum="913CD555F19F68DB" modified="2024-11-27" version="1" fragment="single">DMEVVKKLWSHGDISLEVYTSMGRMFGQKSSFNEAAPGFSRTSFEQKHLELNTFKTLQELEGLAITKRVESLTEEVNRQVEREKMLQKKYEELLFKKTKFEGELEVASSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG52</accession>
    <name>A0AAV4XG52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017742">
        <property type="protein sequence ID" value="GIY94077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="18566" checksum="132FBAFDD924BF58" modified="2024-11-27" version="1">MEIEVDYEINTRTFPEDLLILADNTTMLYLSVYDIPWTKKFTTNERYREFCRKYTNIIINTIHSDLFTWELELELCPKYWSTHEATFRNCVRHIKYQAKLYPYKKNVFFYYSHYVLSAAKFYYKLGLGEAPMLAFLEVISLAKSVFPNGVFDAVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGW5</accession>
    <name>A0AAV4XGW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_608971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000324">
        <property type="protein sequence ID" value="GIY93909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8862" checksum="0BCD11CE943A180E" modified="2024-11-27" version="1">MQMSDLRHCCAYLRPNEFGFALIFGSNNFSQCISYDSPTTPARFLSHWISEGIHFSFTPKVKRDRAPREKPRGAIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH85</accession>
    <name>A0AAV4XH85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1758 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_223723_1</name>
        <name evidence="1" type="ORF">CEXT_467741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000236">
        <property type="protein sequence ID" value="GIY93124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16305" checksum="0F591CC1187607EE" modified="2024-11-27" version="1">MSRDSGKKCENCSGYKRVYYGTSYYVYSFMYGRSTSYDLMVENLDFGYGDDYPEIELLIGSDIYGQILTGEVIQLNEGLTAINTKLGWTLCGEPKELNVQNLEGAQSMLITNLHVQNMKASDMWDLERIGITDEVQTFSKAVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLI1</accession>
    <name>A0AAV4XLI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_147176_1</name>
        <name evidence="3" type="ORF">CEXT_330941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000434">
        <property type="protein sequence ID" value="GIY94801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY94801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13515" checksum="86E505CC7F0DB2CE" modified="2024-11-27" version="1">MEERTVDDKSSRTSPVGSHKNHSRFWLCVERLKSGSLQLWVLCLTSWILLFVYRYRLVHVEDRLSVLEYRFDTLGMNLNPSSSMDHLHTYVKSVIRQVSIYDALSLLACTSVNFNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLQ5</accession>
    <name>A0AAV4XLQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_126524_1</name>
        <name evidence="6" type="ORF">CEXT_28121</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017995">
        <property type="protein sequence ID" value="GIY96042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044545">
        <property type="term" value="C:NSL complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20104">
        <property type="entry name" value="MBT_PHF20L1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043449">
        <property type="entry name" value="PHF20-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15856:SF51">
        <property type="entry name" value="MBD-R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15856">
        <property type="entry name" value="PHD FINGER PROTEIN 20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Tudor" evidence="5">
        <location>
            <begin position="130"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="5">
        <location>
            <begin position="201"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY96042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="526" mass="60461" checksum="1A0B7FCA8F4C0492" modified="2024-11-27" version="1">MNSGSIAESNMDVNEDNALAVPDSEINKSHDEKLYQNKLEGDADDEQPCAKRIKVSTSRINEPEGLACEIATENAVNAWVQCLKVISDKKAVKNFAIKRNSKGKRKRSYAGSKASTESFPIDKFPQRSGITWKVGAPIQAYEKNLWYEARIIDINCVKCLVKIHYLKWNSRYDLWLPMESDLIRSIENQISEPNVTKELYQQFNVGQNVLAKWKDNNFYEAVVKKCLGNDEYLVYFAPDGIQRKKHASDLKEYDISEVERINDPIKIATKQFVHYHGYELKVKEPKDQTLPTSEKPLEIQEDKLGKQNFINQITTKINEAEIETNSLIQCCFKENVSSEDLCKNKSSNLNNSSYIGKQESESEFSSLSVESSKEIQDEDESLLPKRSSSRKVSLPAKFANSEIFLISPVLKQLHHSTAAQNNALAQDEVCDTKRVSKKNKILPENLHDKKIIKENITSKSTKLICTKPFRRNETQMDILREHQKIKIVYWLLLKILLNHISELCSLIKMKTHFRKQYLQIKEEVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT52</accession>
    <name>A0AAV4XT52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_617071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018153">
        <property type="protein sequence ID" value="GIY97355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8424" checksum="53ECCA3ABCF84E5D" modified="2024-11-27" version="1">MRHHLFQVLFKKRRHPPYYEDLSFLAVPAIGIKPFERTEPSTEVRSCFPLRARKQQLKSFQRTDALEPIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVT3</accession>
    <name>A0AAV4XVT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_75541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018225">
        <property type="protein sequence ID" value="GIY97878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8999" checksum="361C14F1898350B6" modified="2024-11-27" version="1">MWDGHGILLKKMSSWTINLTVVDDSRYVTGGVVTSSHRKEEEKRSTCLVHTQSVSHDQPTSPTLLRFPSLPPPVIVLEGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWG2</accession>
    <name>A0AAV4XWG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_493441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018270">
        <property type="protein sequence ID" value="GIY98235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16521" checksum="D1BA43B054AA7600" modified="2024-11-27" version="1">MTSYLFFTELQQRNRGRSKIPQCQMCRTKREFRCCTIVKGFTCRLFKEVKPQFSLVQGTAILKRMVNDVDLWLTNVQECLWFLIKLTLLVRRTLRLGGLQAFFEDRQLLSLTAFAHCCCSSLPPEIDPTPTPSRLSHQLLCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2T1</accession>
    <name>A0AAV4Y2T1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_4681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018701">
        <property type="protein sequence ID" value="GIZ01663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2T1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10479" checksum="B5A60C6E714701C0" modified="2024-11-27" version="1">MGRFLQERRKNMVQDNRFQPERRENIGIGWQIPTRKKGNYRNRLADSNKKGGKIWVQDSRFIKKGKKIRLQQISKKKEGKYGNMLADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y649</accession>
    <name>A0AAV4Y649_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sorting nexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lst-4</name>
        <name evidence="11" type="ORF">CEXT_805841</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001495">
        <property type="protein sequence ID" value="GIZ02727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y649"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07626">
        <property type="entry name" value="BAR_SNX9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06862">
        <property type="entry name" value="PX_SNX9_18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11763">
        <property type="entry name" value="SH3_SNX9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000004">
        <property type="entry name" value="Sorting nexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014536">
        <property type="entry name" value="Snx9_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019497">
        <property type="entry name" value="Sorting_nexin_WASP-bd-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827:SF1">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10456">
        <property type="entry name" value="BAR_3_WASP_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027744">
        <property type="entry name" value="Snx9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="10">
        <location>
            <begin position="196"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR027744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR027744-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIZ02727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="540" mass="61070" checksum="CD269A9FD1285935" modified="2024-11-27" version="1">MAVSFQVRALYDFDAEAGSGELSIAANEILTVINQDVGEGWWEGVNSKGQKGLFPAGYVEATNSAPPPAMPPPPPPADAQITAFSESVLPGVDAVDDWDDDWDDDDSVYSQDHVGGIQSQVSNASLATSRDPRESQRVVETRGTLKKSFNRFSTFVKSGGEGYILGETNISVPTEQCITIIETNGEIKWLESLSPYTCCVDSPNKKTKLKGLKSFIAYQLIPSFNNIAVSRRYKHFDWLHERLEEKFSSIPIPPLPDKQISGRYEKDFIDHRKNQLQMWVNRICRHPVLSQSEVWMHFLTCTDDKRWKIGKRNAEKDKLIGGSFFHAISTPSNPLDNGCVEKQIDHFNRFVIKMDDSVKQLFSVAIEQHKRYAGPVKKEIQRMSESFNDLGTAFEMYNSDTSNPLTAAIKHTASVYEDLGKMYEEQPKYDAEPMADVLHEYKGMLAAWPDVVHIQKSALNKVAEHKKLSEDGKLSQDDVAAISQRTDVISYATLAEINHFHNERVAYFKSMMETYLTAQIDFYQRITQRLQETLAYYQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8R8</accession>
    <name>A0AAV4Y8R8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pol_390</name>
        <name evidence="1" type="ORF">CEXT_242351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018978">
        <property type="protein sequence ID" value="GIZ03627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13363" checksum="251FAB86BB42AAD3" modified="2024-11-27" version="1">MERMVNGQLAYAFETKGVLSKYQSGFRHSREQLPPYVTGSLFMNDLQISCASVNMAFIERQLQTAVAAITKWADNNGLIFSFQNTLCVHFCKLRGLHSDPEILLYGQSIPVVSEQRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB90</accession>
    <name>A0AAV4YB90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_84965_1</name>
        <name evidence="2" type="ORF">CEXT_242311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018978">
        <property type="protein sequence ID" value="GIZ03620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10995" checksum="947350E23645776F" modified="2024-11-27" version="1">MEEKICRINRPVAPRRLIQDRSADSGISPDAGSPMLLNESYDVLMMNNNALCSTPSAPLLVEESCTMWIPQHDLADDSECGTDDSPLENRNNSPNYNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFS7</accession>
    <name>A0AAV4YFS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_266375_1</name>
        <name evidence="2" type="ORF">CEXT_172012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019209">
        <property type="protein sequence ID" value="GIZ05110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="28131" checksum="8B479E8C279B279C" modified="2024-11-27" version="1">MFEGSNQCRYEEQNDFSNGHPEPSEEPENGTVGLLEVSRTLYGVEDSSTEDNRTLEGCGSNLLSVQVKCEDIKWSSGMCSSEKESASHPSLVPHELRENSFEDARSPTDADYRDIDSNSRYPDEPVSQSFKSSEYPEGRSIYSSVFTLRDPYLGYPNQLLQYPNDFVGQGESFSNFSSAKFSPGQSHSEIYRPVVTTLRSSENGGFGVVYPESRTQAFEPDGYPELYCQLNVITNGKNNFRTKPISFLHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YGE5</accession>
    <name>A0AAV4YGE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_781581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019301">
        <property type="protein sequence ID" value="GIZ05369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YGE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10476" checksum="C187AA0D1E8A1EBB" modified="2024-11-27" version="1">MIAIGIASNGSLDNAFDDILRNPVFRRHSTGALFRHSRKCWGTNYLEPFRQLLSEIRRSQNWRLFSASTRRSRVAIKATRDGSNFYSKGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3T3</accession>
    <name>A0AAV4M3T3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_723831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001851">
        <property type="protein sequence ID" value="GIX67111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3T3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14034" checksum="8C2F931C2E5D8645" modified="2024-11-27" version="1">MRGQIRLHPLPTSEAKKCAWETDAILHLSGNNSNRFLAKTDTLQISFKRETANICMRGQIQLHPLPTSRGKEVCMETGRADFTSLVATAIDFSQQTDTLQHPLKRGTGQHLHLQIQLHPLPTRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M532</accession>
    <name>A0AAV4M532_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_723641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001851">
        <property type="protein sequence ID" value="GIX67068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M532"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="14768" checksum="5EF2C9FD6CC7F20F" modified="2024-11-27" version="1">MGGQIQLHPLPTSEAKKCAWKPTLILTSLVAHPLPTAIDFSQQTDTLQHPLKGTANICMRGTNSAPSPSYLQGKKCAWETDADFTSLVATAIDFSQKTDTLQHPLKGYGQHLHEGTNSAPSFLPPEAKEVCMGNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5S6</accession>
    <name>A0AAV4M5S6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_740131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019394">
        <property type="protein sequence ID" value="GIX67384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5S6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9043" checksum="C4566DA9590D326F" modified="2024-11-27" version="1">MKRLLDSFSVNLFHTWEDKARLTAAGVLTTDSFKLDNQAMRRRRFTRMVRNNSPLFATLQSDAAAVLIVVFKETWQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8T2</accession>
    <name>A0AAV4M8T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_170471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019471">
        <property type="protein sequence ID" value="GIX68235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12378" checksum="FF6174F02E55DADB" modified="2024-11-27" version="1">MLLSSPLMEGGKSFCSDGAAAESTSGGGCDEESFSAGFVATFISSCALVTEISFDLNRFKIAELCSVRRSELAQKSLFSSGSTIIEVPGSPYSLPPPSHRSPGDVIFPSRFARGNCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBY5</accession>
    <name>A0AAV4MBY5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRKDC</name>
        <name evidence="8" type="ORF">CEXT_545271</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01002007">
        <property type="protein sequence ID" value="GIX68921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004677">
        <property type="term" value="F:DNA-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05172">
        <property type="entry name" value="PIKKc_DNA-PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037706">
        <property type="entry name" value="DNA-PK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF68">
        <property type="entry name" value="DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="6">
        <location>
            <begin position="28"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="7">
        <location>
            <begin position="379"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX68921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="411" mass="47043" checksum="06964253EF7AF6F9" modified="2024-11-27" version="1">MSSNSGNTLLRLKFLASIRAKVNPCQSTTLKFLVLTSLTVPRRITIRGNDEKEYKILVKSGEDLRQDARIQQLFSVMNDIYANDIHCSQRHLSLRTYKAIPLNNRLGLIEWVDNTTVLQDFLKDGMSEKERKSQDDTLPLKNFRQWACSKTPKNPYFYLYLNKSREEKSFLKLSSTPEAYMILRTKFAQSHAVICLSQWILGIGDRHLRNFLVDKSTGCEVGIDFGHAFGSATQFLSVPELIPFRLTPQYLQLMGPLQVKGIYESTMVHALSAICNKRDLILNVMDIFIKEPTVNWEIHANKQLQDLGLSAEALVGKEDWFPKQRIQIARKKLEGFNPCYITRTVLELGHKSKKDIFKAMESVCVGNVESNVRAKMKKNGLTVEEQVDCLIDLATDPHVLCLTYCGWNPWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLY4</accession>
    <name>A0AAV4MLY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from transposon X-element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X-elementORF2_292</name>
        <name evidence="2" type="ORF">CEXT_2251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002356">
        <property type="protein sequence ID" value="GIX72900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF2">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="71"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="28148" checksum="883EE62A47473633" modified="2024-11-27" version="1">MPLFYVQLHNNSEVGNDTSETTLLGTRISIEKEPKYSKNTPGDTGFKLFSTRTVNLHSLRFGSWSSNGLIKHLNEVIEFVSDHDLDLFLIQETCLQPGREPKIPNFTLYKTDRINYSNFRYFGGTCIYVKNSLNHYQLPTPQMNGIEATIVNLQVTDNTKVPSASTYCRHSATFPVDDLSKLLNMQPHVIVAGDFNAKRTSWHNTSNSTRGISLNKHIRNRHDTKIIAPTEYIHFNSKKTCEQHYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MP97</accession>
    <name>A0AAV4MP97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_525451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002437">
        <property type="protein sequence ID" value="GIX73695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MP97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="21422" checksum="571F1A40765B0633" modified="2024-11-27" version="1">MRFPIMPEAQPLPVRMPYEKQIDLPELDRDYYGPLIVHYLILQKPDRPSRTRQGLLRPTNCALSLSFRSQIDLPELDRDYYGPLIKPDRPSRTRQGLLWPTNCALSYPLEADRPSRTRQGLLWPTNCALSYPLEKPDRPSRTGLGYLWPTNCALSYPLEADRPSRTRQGLLWPTNCALSYPLEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPE5</accession>
    <name>A0AAV4MPE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_525381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002437">
        <property type="protein sequence ID" value="GIX73685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9592" checksum="EE1247B17322F899" modified="2024-11-27" version="1">MHLFLRSSIDRHSHTGFFYVPFFRVTHIVGGRQDILEGGCSPSLPPLPCPSQGERGVPNDRILTTQAMCLAFHPCSPHLHAKKNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQQ7</accession>
    <name>A0AAV4MQQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calmodulin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_288331</name>
        <name evidence="4" type="ORF">CEXT_538481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019683">
        <property type="protein sequence ID" value="GIX70528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01002445">
        <property type="protein sequence ID" value="GIX73811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQQ7"/>
    <dbReference type="SMR" id="A0AAV4MQQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000527">
        <property type="entry name" value="Calmodulin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX70528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX73811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16811" checksum="6B44A8917FC7027B" modified="2024-11-27" version="1">MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUU5</accession>
    <name>A0AAV4MUU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_204591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002600">
        <property type="protein sequence ID" value="GIX75588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="250" mass="29365" checksum="66F1328B77C77432" modified="2024-11-27" version="1">MAKIGKRSTILQAAMFVAIFSMHELSNPDNSNYQQRPYSDYLRYYSSKGNSYDYEDPVIDYLRYYISKGDPYNSDNQQDLDPNYIKYYSFNDPSLFKSNQIHYRVSGQDGEKSFLELLKAKLWDYETGETVAERASSGIKGGDYYMQTVGPYLYRLPKPRHHETYKSVTLPYQIYDNRKISMRNARKGYYLSDAHKKLLPWEGMSNSEEEEALKNEVIYKNVTLPDQIYDNKKKTARAMQEKLHLLKRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N059</accession>
    <name>A0AAV4N059_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_398911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002818">
        <property type="protein sequence ID" value="GIX78076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N059"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16655" checksum="CDA4761E66B6D086" modified="2024-11-27" version="1">MRKGFQNKRSFKIYIDDQNIYLKPGGKAAICFAMQSIFYDAMKEMENSKWRSYYRDVGDYLPDSHVNKRNASYYEQMINEVGFEILYLKEESTADVFSSDEVYKSNFYTFVLTISDDGQICIKICTNNSNQNRNQIFANTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3S2</accession>
    <name>A0AAV4N3S2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_546261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002929">
        <property type="protein sequence ID" value="GIX79348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3S2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="22909" checksum="AE5D45BB0105334B" modified="2024-11-27" version="1">MEDEALWSFARQSGSSTLNQINQPLKQINISRQQSISSDIHQGIDCEVTTTAEMASQYGDPNQNSYIPSDFETKPSDYLFPDIRHMQENDVLSTHLQLPPEVSNAFINQNPQNYESSTSEHPENTPMSVATPCVLTGFQQTFDRRNSISCATHPSESGVNCEKYSKDQSLGGAACASRNMDAPQETKNPLYESSKCPMQFKRKEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N407</accession>
    <name>A0AAV4N407_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_806331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002822">
        <property type="protein sequence ID" value="GIX78119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N407"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11008" checksum="9F498305C0695D56" modified="2024-11-27" version="1">MHLQQHLNFSSLSTTVSTTPVSNLDDSSTSAQLTAPNTVGSSTAISTLPTFLVLMAIIYICKTPVSSIEITTPASNTFGSSISTSSIDKSSTAVSTLATTPAAAPSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N976</accession>
    <name>A0AAV4N976_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_86621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002992">
        <property type="protein sequence ID" value="GIX80009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N976"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15777" checksum="6C63E487355606DD" modified="2024-11-27" version="1">MRDDKLQKDDIRQSIVGGGGGFRSLHFRSPIERKATNAFAHVELCASASSRSVRFSPKALNDSSGRLLSNGILLFGSIYDEMKCSPCMFHLQRGPEAFSAPILLLEPNFDPFSNASASPSHDSADSVRPRKTRQTVNSECFHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEY7</accession>
    <name>A0AAV4NEY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_812821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020783">
        <property type="protein sequence ID" value="GIX82428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11148" checksum="FD072610606FB8E1" modified="2024-11-27" version="1">MGYLAPTLPYIQVCGANPFWSSEMQTEDWVSLTNCGGAYMHYDYLMSDLPCADELSLLYYLRRFFPQMPAADMTFYGKDEFVCKLCKILTLKIRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NF69</accession>
    <name>A0AAV4NF69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_220061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020826">
        <property type="protein sequence ID" value="GIX83014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NF69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11007" checksum="146630357EC802DC" modified="2024-11-27" version="1">MLIKTCLWVEIPYKTITVQHQCKEKVSNYTTKVANHFFGCYLRSYGHCTFAHDSMQDSLPPQHDLPFQAEIDSPDNCLQYVPLEEEGVRISFSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJK1</accession>
    <name>A0AAV4NJK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_112181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020872">
        <property type="protein sequence ID" value="GIX83487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12372" checksum="38CFCCAEF9D6AFC9" modified="2024-11-27" version="1">MAKIRQKKPPNHADAVRDEENPVPQSRARSLGGKAVLFGRGFPFPHCYGLSATSDSFSLTLFLATYIRIDTGPLLSLVSSLPLLYVYEQASNSPSHAVCCTPIVRPFFPHWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWV4</accession>
    <name>A0AAV4NWV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_146610_1</name>
        <name evidence="5" type="ORF">CEXT_785451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021305">
        <property type="protein sequence ID" value="GIX88248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043551262" evidence="4">
        <location>
            <begin position="16"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX88248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14481" checksum="169FEB584E41566E" modified="2024-11-27" version="1">MKVLIILALAVAAQGAVVVYHPAWWPSASAYQAKDGLGNYAFGHHNAQPGGPSFHSETGDITGKKVGSYGVKDADGKVRIVDYVADHEGFKANIKTSEKLPEDHQDAVGVKTTELKPGEHVVYSHPLPYYYVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NY16</accession>
    <name>A0AAV4NY16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_559191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003891">
        <property type="protein sequence ID" value="GIX89842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NY16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15450" checksum="0654C54D47FFDFEC" modified="2024-11-27" version="1">MSRSFHLHPPSPQPPLSKIPCPKIADKCICLVTSYFCKSVSVALEFFPGRLSVGVWNFVKCPQGPLMGNMCTQKEGPRSVLLDGRDLSSGALVVEDQSVELRGNALLLLNLFLDGENSLVLFINHPEEHLCDLLQLRLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYD0</accession>
    <name>A0AAV4NYD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LRRCT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_131243_1</name>
        <name evidence="4" type="ORF">CEXT_172091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021450">
        <property type="protein sequence ID" value="GIX89776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="201"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX89776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="520" mass="56829" checksum="1592DA24BEBD6EA5" modified="2024-11-27" version="1">MAVFKQDTVDNALKRKLLGADRKRQSRGREAASRRSCATWTCAPIGSAPSPSAPSPPPPNELTSELDHDPCFNNTSKLDNLSHKIATLLGRKRPMEKAKHEFETSCLHGHNAQSARSGSRNQLVFGRQLASLFRIHLLHFSAADNPLRCDCTLLGLIERLNSTELLLPPCAQPQHLQGRAPDEVPWRTECPEDTVRYMDTGNSDVVHVKPRSPTSLAVSWRSRDASGWTVVYRREEDSPYQMTLAPHDHRPGDITLEGLQPRTAYVVCLAHVSQSRYTVEVGRCATARTPGAPAHTWTELEEVGAAAQSVSISWRLRAQGLLDDVSYRHEWTVRLRRKGAQYFTEVPVYDITKGAETDGQRYEYALGDLAPRTWYQVCLVDVEHGALEGKGEAVAPANASAPVCEEALTLGQPALQGAEIAAVVFACALCIAVCVVTVVLCYQKKLLKCKQPATPPETPPPRPETPPLRKVQGTTGSGDPGRPQSHPGHGAPPAVPQLQDSGLQGRPDFRSPSTAPDTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAA4</accession>
    <name>A0AAV4PAA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_810971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004324">
        <property type="protein sequence ID" value="GIX93999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18147" checksum="334B8EAC21BD4B52" modified="2024-11-27" version="1">MLQSHYMALIGNLFGNSAVLLEEKKKWQINSRFSAGSASFQGDKRRDSRHKFLSLIATSRFATTALTASHRRYGIIGGHRREPLTYGTVGSLSIDLTLPHHRLSGPSACTCYGHRMTTEEIGILCNTFCIAVEADFERERERQRMKTIIEILFAVQKYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGQ3</accession>
    <name>A0AAV4PGQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serpin B8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SERPINB8_6</name>
        <name evidence="3" type="ORF">CEXT_363281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004611">
        <property type="protein sequence ID" value="GIX96148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serpin" evidence="2">
        <location>
            <begin position="46"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX96148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10413" checksum="8CD961328DAE5CC8" modified="2024-11-27" version="1">MRMLILLPERRNGLSDMESELTNDILSEIPLNLREVPVQVTLPRFIVHKCAVQVNEEGGEAAAVTGVSAGVRTGGPLVPLFTADHPFLFLFKIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PIH5</accession>
    <name>A0AAV4PIH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_23911</name>
        <name evidence="4" type="ORF">CEXT_516621</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004702">
        <property type="protein sequence ID" value="GIX96823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PIH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:DNA transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057667">
        <property type="entry name" value="HTH_SB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002492">
        <property type="entry name" value="Transposase_Tc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25787">
        <property type="entry name" value="HTH_SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01498">
        <property type="entry name" value="HTH_Tnp_Tc3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sleeping Beauty transposase HTH" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Transposase Tc1-like" evidence="2">
        <location>
            <begin position="70"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX96823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16280" checksum="82E1071E6D481970" modified="2024-11-27" version="1">MPRSSELSDFEKGIIIEYHKCGRSLRDISSDLKYPKSTVVYVIKKWKVSGDCRNVPRVGRPTKLGDRDRRVLTTELRKNRTQPMALIREEFQQASGSIVSMNTIRKEPHLHDFHGRAAAHKPLITKSNRAAQLMWCKAHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPN2</accession>
    <name>A0AAV4PPN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_20852_1</name>
        <name evidence="2" type="ORF">CEXT_332881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004750">
        <property type="protein sequence ID" value="GIX97182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17191" checksum="4DB7D7F6B2743EF9" modified="2024-11-27" version="1">MPLKETATKGTKVLTGLETETETAVIQKPTFWSYVRKAFFNPMFILSIVIVPLTFIAESILPSLLDMLGSNMLPVITSTIASGFARSFDINAVEQVLDFVNEYGARAVEDPRCFQRFLCQASRSSLESRSGDSWSIQKLFESFLKLLMTGFGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPS5</accession>
    <name>A0AAV4PPS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_438481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004871">
        <property type="protein sequence ID" value="GIX98166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9377" checksum="6800CFCFC06ADF89" modified="2024-11-27" version="1">MIKSGHYPLTARCSMNLSWPQFKNYRWRTQQRQKKREKQKQSLPRSPGVIDNRRNSTIRGNRGGLFCSLRKILEKLSSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q088</accession>
    <name>A0AAV4Q088_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_429721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005391">
        <property type="protein sequence ID" value="GIY01956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q088"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7881" checksum="E9C8457F5D6EB212" modified="2024-11-27" version="1">MAMEHKGTSQQANRIGKNLSLVEQRRWSRRRSRSVNRTFHILHNCKGMGKLNKEDALFVFRETDATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q671</accession>
    <name>A0AAV4Q671_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_387711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005849">
        <property type="protein sequence ID" value="GIY05483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q671"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8670" checksum="22ED88E499A12C2D" modified="2024-11-27" version="1">MFPLNGASSNMGNRFSPISCPLFSCKAPIDPMYLLHHQKEQPFHYFPKETPLTTAGQRLVRQFGRKKWSFVFPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6K1</accession>
    <name>A0AAV4Q6K1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_140741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005863">
        <property type="protein sequence ID" value="GIY05633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6K1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016600">
        <property type="term" value="C:flotillin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002020">
        <property type="term" value="F:protease binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901890">
        <property type="term" value="P:positive regulation of cell junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000049">
        <property type="term" value="P:positive regulation of cell-cell adhesion mediated by cadherin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045807">
        <property type="term" value="P:positive regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070528">
        <property type="term" value="P:protein kinase C signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002090">
        <property type="term" value="P:regulation of receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03399">
        <property type="entry name" value="SPFH_flotillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF46">
        <property type="entry name" value="FLOTILLIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY05633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14019" checksum="29A328F5ACB13ACF" modified="2024-11-27" version="1">MPGFVTCGPNEALVVSGCCLVNPTIVPGGRVFVWPFIQRAQKLTLNTMTLTIESPKVYTQQGVPISVTGIAQLFFELSILLFVTPKKTSQIQHIARETLEGHQRAIMCTMSVEEIYKDRKVFQASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6T9</accession>
    <name>A0AAV4Q6T9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_263731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005697">
        <property type="protein sequence ID" value="GIY04319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6T9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10572" checksum="14463D3A22B372DF" modified="2024-11-27" version="1">MTAQLQATSVTSARLQRHLSVWVGEAHIPYVKRCWKKKKPELKRTYKERQKEKRVGVSTPQSYHVPRFHLSKDCRGNRLSPICGRKEELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAY2</accession>
    <name>A0AAV4QAY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_721291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005854">
        <property type="protein sequence ID" value="GIY05511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14873" checksum="9B88219C7DCAA0FB" modified="2024-11-27" version="1">MRLTNGSFLIIPENEIRVAAEDKDDFPAVAKRCITSFFSNCSASETGNEWSAPKARSSTTNGNILFWLVQEDSSSSRAILSSLTHHRSSVGSKKVHCSTRQEIDTRFHIQRAFSLPPDLSRNTLARGFVTLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QI75</accession>
    <name>A0AAV4QI75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger protein GLIS3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GLIS3</name>
        <name evidence="10" type="ORF">CEXT_400071</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006177">
        <property type="protein sequence ID" value="GIY07932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QI75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="481"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="512"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="224"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="573"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="619"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="711"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="363"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="585"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="620"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="637"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="724"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY07932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="744" mass="80564" checksum="401A803D75C14B7D" modified="2024-11-27" version="1">MRTNAITPQSSVAEAGGQSNLMASDMPSILNDLSMFMIPQNNLAMDSTTLQNVNKTALTTKSTTTTTITASGNSYSNVQYQPKPDSSFGRFSVLPSVTSNTTPHVGGFGDGDNISLLSYTSIPGNAQNSSQMGMYGTSFSPFSVNFHESIPSAFTSSPRYSGRSSYSSRSRNKRALSNSPLSAEGIDLNSIIRMSPTSLVSYINGSRSSSSCVSPGSLGEKTGCYGHLSARNSSSSPHSGSASSGNRRSSSYTPQTGTPGNNSNITSDNSNLSNTCLRNERAKNVFLNMDDSILMMQAMQDLESEVDISSTTSLPYGNHATQNTQMMPEFENLQVLPQDLAAFATEEFMPFIPTSLPPVHTHMQLQPPQPVSNQSLPALGQHQKPPPTYDQHMARKALLQKNSSSDSSQPSNSSSFKALKEIKRWEEIAVLTLKAIECTHVDGYILGINLINVRLQAVKSIFQTGKFENSSQIPHWRKTFYSCTYPGCSKTFSSNSSDRTKHQKTHQDTKPYVCQVAGCDKKYTDPSSLRKHVKKSHPEKKEPDRKKIRGGMEELDPKDLSECLVIQAIKPTVLRDVSPPEPTDSGLGRSPRSSQPGSSSDHYPGLIYSGETLSVNEAVHSSCHTSPSSHHSSPRSQIDSGESLPPNNNSLRVPVLPPIAPPLGQQNYTFPNQIMTNSRNTPSLPRETNSANLSCLTRNFPNPSPNAKLYAGTTPRAASGAHSACSNSMNYKQPDSSSRSTLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QL35</accession>
    <name>A0AAV4QL35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein SCAI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SCAI</name>
        <name evidence="1" type="ORF">CEXT_351931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006323">
        <property type="protein sequence ID" value="GIY08979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QL35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022709">
        <property type="entry name" value="SCAI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21243">
        <property type="entry name" value="PROTEIN SCAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12070">
        <property type="entry name" value="SCAI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="230" mass="26791" checksum="B0F52DC5400E398C" modified="2024-11-27" version="1">MLKRWQIGEIASKIGQLYYHYYLRTSETNYLNETFSFYAAIRARGYYNKASKEERSDLMVKKLRYYYARFIVVCLLLKKMKLVKELVRGKIEKKKMQIRNSSILKKLAKQIDDYTSTYEPEDQLEWSLVLGEIKSFIEADNLVNITDVNSAPVVLSHRLNPLNSPPVEKLPTNHLTLQEILIVGNCCDQPPDNGDQRPAKRENPHKYLLYKPNISQLIVFLSSGFKELPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPA9</accession>
    <name>A0AAV4QPA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_206291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006656">
        <property type="protein sequence ID" value="GIY11533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11683" checksum="CD504AADB95F8305" modified="2024-11-27" version="1">MDQILREDQNKEAHFVLQCTKYAEILGMHENCNILQQSTLTLIFSGNALFVEEITFTCDGVVNLHNSYVCATSNPHAFQEWFSFSVWADPVNDFLIGPYFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXP9</accession>
    <name>A0AAV4QXP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_267351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007080">
        <property type="protein sequence ID" value="GIY14413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11904" checksum="2AC8F39F860EA8C7" modified="2024-11-27" version="1">MNDKYLPRKESFENFSENYRWKNSHNLFKNPSMVIAAPTIFCIRVAAAARGTNHIGGKYERRKWINRRDLGHFHPFLNAVLQTFVSPGTFIITDFSHTSLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZ77</accession>
    <name>A0AAV4QZ77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_754141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006970">
        <property type="protein sequence ID" value="GIY13644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZ77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7522" checksum="84A6AA7939445913" modified="2024-11-27" version="1">MNDSDIDRDSDNDRDGDIATILQYLIRSGQVRIIAATSPHLYHETTDDEFSTNRAPPKGTFNKHFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R053</accession>
    <name>A0AAV4R053_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_700901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006990">
        <property type="protein sequence ID" value="GIY13730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R053"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19244" checksum="A29FFB63C353B839" modified="2024-11-27" version="1">MQKFLPLSLNKYGPLIIQNINAEDLISEDNFKDSSNLQDFNLISCKDEDIKEVLSLLPELKLFYLWILFSNNTKKIFSNGILCTKLFVLNKSLELNRTYRLIQNLDKDCVRLCWLGCRPPSIHRRCPTTAPCGSFCLLRLRPGPVRSALDDLVGPGSRSNPIDTVLSADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0Y1</accession>
    <name>A0AAV4R0Y1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_141431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007206">
        <property type="protein sequence ID" value="GIY15160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0Y1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="50" mass="5665" checksum="CAE3A7E8DAA832DD" modified="2024-11-27" version="1" fragment="single">EEENVIFCTDDDDDEDVIIMKENFSSSAGLTTVINLLLTFSEDCNLLHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3B8</accession>
    <name>A0AAV4R3B8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_809591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007321">
        <property type="protein sequence ID" value="GIY16039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3B8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="10047" checksum="8332221FCEBCF87C" modified="2024-11-27" version="1">MSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLCRMSYLRMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFS7</accession>
    <name>A0AAV4RFS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_665091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007940">
        <property type="protein sequence ID" value="GIY20833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8358" checksum="3221F1D9D0031B9C" modified="2024-11-27" version="1">MGDEASINVETSRRKRTKREHETTTFESEEAARRKKMMEEKKKIRETEGGGNNDNNKTKDRERERTGDKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHP1</accession>
    <name>A0AAV4RHP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_665061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007940">
        <property type="protein sequence ID" value="GIY20827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9933" checksum="CBAE8A278031CC9D" modified="2024-11-27" version="1">MTFKRSHLVERDPGRLKMTFGRQPKEKVLCLPHPSRTYPERDLNILSKIKAHPLRSDKTVKKGGSKGGKGSSRLDIKGRQREVQPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJJ1</accession>
    <name>A0AAV4RJJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein SMG9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Smg9</name>
        <name evidence="4" type="ORF">CEXT_207151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007916">
        <property type="protein sequence ID" value="GIY20657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019354">
        <property type="entry name" value="SMG8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039177">
        <property type="entry name" value="SMG9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270:SF0">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10220">
        <property type="entry name" value="Smg8_Smg9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY20657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="457" mass="51637" checksum="D8561DC4B9997302" modified="2024-11-27" version="1">MAPPSKPKDILSEPDTGTVNTFVILAKPPDKNKTPQSGNSLASPNIQTELLRSPTIAQKTSNVSEQDDSASTHSTASASKDNESFPDIVKSVNHRVVHVQQKPPTVQAMCFNLLQFSFRIVGDQKISSTPEMSYPVKLVDESLQWCDNALEYLHDSSDFYVVGVLGLQGVGKSTIMSIISGIHSEKSKWQLFKPQTNDLKESGEYCTSGIDMYVTNQRVILLDTQPVMSSSVMDHMIQYEKKPIGAQDYHSLDNALTIQSLQQAAFLMAVCHTIISVQDWFIDTNYLRFLRTAEMLKPSTPINVLDLNAIPEGTIEYYPHIVFVQNHSKKKNFSEETITKMEKTLLDVFQKSKLKYLGSVNPQSRTYSKDTPPRVNLFLIPDKEPLDTDSANMFPEYKIHPGYKYLTEALGQQVLSMPRSLLTHIPQSEKHWFHYAARIWETVKKSPLFLEYSRLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RL36</accession>
    <name>A0AAV4RL36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_635711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008147">
        <property type="protein sequence ID" value="GIY22440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RL36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10234" checksum="C9CAB30D1EB6D44F" modified="2024-11-27" version="1">MYDKRYRFFLNQATSAVALLTKPRFIHEHNISLICRPVNMLTCPLLNTPVFGSKWHTNCWSLRVQNTFMILSKTFTPSFPRLQQSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RS26</accession>
    <name>A0AAV4RS26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_447901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008399">
        <property type="protein sequence ID" value="GIY24379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RS26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11564" checksum="D5D9520DF0DBB6DA" modified="2024-11-27" version="1">MGSIAVAVFRNFGFAGMQLLYEIRSHLRALLQSLFFRHDGFLQVCNYYLRFESTYGLYCSRCFLDMSRLCTYAITILDSNPLMGSTAVAVFMGRLGTYAVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSR6</accession>
    <name>A0AAV4RSR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_669261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008307">
        <property type="protein sequence ID" value="GIY23739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13219" checksum="726F8E5D94278D2D" modified="2024-11-27" version="1">MRPTKAPLQKMVKEEIENRFLPGRHVKKNCLPLLKQAFNRTRGSHDAAPSFFNDILAKSKPNLSRHSSREWMGHSLLSAHDESRTDSFRRPVLTRIGMDSHDSDSSDWMMRFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTJ2</accession>
    <name>A0AAV4RTJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_243571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008485">
        <property type="protein sequence ID" value="GIY25050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7441" checksum="5110B21A89A481BD" modified="2024-11-27" version="1">MAEMKVEDAEEITNTENDTKMMERQLAVVHDWNGIAHDHSKTTSNEGIPDGHAASTKKKGEVALAHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S810</accession>
    <name>A0AAV4S810_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_661151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009036">
        <property type="protein sequence ID" value="GIY29211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S810"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10246" checksum="689EA246CE560828" modified="2024-11-27" version="1">MVRLLTQKRNSGALKSTQRKRALRPTPCPTSNPKDHPNQKFVKRIRKWVHVHRRSKVRLLQKHGLIKDQPPPLHILQQNIPNRLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8J2</accession>
    <name>A0AAV4S8J2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_577991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009006">
        <property type="protein sequence ID" value="GIY28946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8J2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16754" checksum="896BF7AD3E9B0FD6" modified="2024-11-27" version="1">MCRFHSREWVILQPPSFREDIYGSGSLKRGPLWGKNNSYFNFEVSIPNGRAKMCEASSWCILVKMILLCIFLAEEELGPNTITISLFTFSYSFFKLLLSFPVGICITDVLLMSVMQTSTGQKVATEFSLRHRRHGFDQKTNINKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8L7</accession>
    <name>A0AAV4S8L7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Synaptic vesicle 2-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">svop</name>
        <name evidence="8" type="ORF">CEXT_784981</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009020">
        <property type="protein sequence ID" value="GIY29072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY29072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="351" mass="39602" checksum="EA238AE6FF9AB9F9" modified="2024-11-27" version="1">MGSIGVILLMWLVMVYVGSWRVLLVCAAVPSFIVILSLKWYPESARYYLVSGQQENAERILRKLAETNRAELPPGRLIHVGEKAKRGRIGDLLSPDYRRTSLLFWYIWLATAVGYYGIALLSPLIIQKGSLSVEGANGTFGYNMRDPVPCSRFTRQNYIDLLWTSAAEFPGLIVFTFLVERMRRKTLLCCACIISSILSVLLLLKAHKILNLLILFAARATLVSIFQLNYIMTSEPWELALLLSIGRPHSSLYSTSVGAGKPCSCHVSARRSTADCRSDGHFLALRNQRSRHERISHLPKVTACKSDSTERFWRKIEADATTNLKLVTSHIIQVLFLRLNFRSGKRGRLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8W9</accession>
    <name>A0AAV4S8W9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_312841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009091">
        <property type="protein sequence ID" value="GIY29571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8W9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9585" checksum="3D4028056059FD6B" modified="2024-11-27" version="1">MVFPTVFLSCGFPSKPEWITIVPSVERMIFWLSPKRVLQFWFLESELNPNSKIHDNFNRTIKEAAELKDFRPHIHFDKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9A6</accession>
    <name>A0AAV4S9A6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_5302_1</name>
        <name evidence="2" type="ORF">CEXT_254331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009035">
        <property type="protein sequence ID" value="GIY29201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9A6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10769" checksum="EDA5C689BBFC7997" modified="2024-11-27" version="1">MMIVGVQTTVYLKPSTLKREKLPLRWWNIITLIYLHLFSLKAIVALLLTRGGLGFWMQLTTFLRSSVATISADIYVLKRKKQAAPFDSENESLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGE4</accession>
    <name>A0AAV4SGE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MLX-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Mlxip</name>
        <name evidence="8" type="ORF">CEXT_299441</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009390">
        <property type="protein sequence ID" value="GIY31542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11405">
        <property type="entry name" value="bHLHzip_MLXIP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF37">
        <property type="entry name" value="LD38259P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="75"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY31542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13042" checksum="AC7F8C432220E8C6" modified="2024-11-27" version="1" fragment="single">MSSASSVGDLQQSLFVGPASSSQDSPPTCVLPTPDSPGSSTHSSSPAISTVSFESSANKSVRLKSDEEKVQYKEHRRVCHINAEQKRRCNIKNGFESLHTLLPPMGQTPNSKISKAAMLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMS0</accession>
    <name>A0AAV4SMS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_720331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009572">
        <property type="protein sequence ID" value="GIY32973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043371751" evidence="1">
        <location>
            <begin position="20"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13426" checksum="6A838BA35D314FDA" modified="2024-11-27" version="1">MASFYLLSVFLFLWSKLFGTSYLQAIISFEQAICKLLFLLNRLFASYLEQAIISLEKATGKLFGTSYYLEKAIGKLFGTSYYFFGTSYLELAIIWNKLFASHLEQAIIWRKEIWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SPJ6</accession>
    <name>A0AAV4SPJ6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Intracellular hyaluronan-binding protein 4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_652521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009979">
        <property type="protein sequence ID" value="GIY35914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SPJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039764">
        <property type="entry name" value="HABP4/SERBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032381">
        <property type="entry name" value="IHABP4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299:SF17">
        <property type="entry name" value="AT19571P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299">
        <property type="entry name" value="HYALURONIC ACID-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16174">
        <property type="entry name" value="IHABP4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Intracellular hyaluronan-binding protein 4 N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY35914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20932" checksum="E0308F16D7466100" modified="2024-11-27" version="1">MENAYGIGVKNRYDIFYDEDVDPLEIIRQQEEEKEKRKTDKSHPKDKNKTTKTGKTSPATALSKKSKDAHAVTPPKLTETSESSNKPKSRPFNDRNARNSRNFEESRDFEERKNFRNRVDHGSSAEIRERDPETRRGRGGFRGRGRSRGRGGFFNYDNRPPRREFDRRSGSDKNWITFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQI1</accession>
    <name>A0AAV4SQI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_521971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009802">
        <property type="protein sequence ID" value="GIY34745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY34745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18262" checksum="35429391CF4DB6E4" modified="2024-11-27" version="1">MFQKLGIDFKVGIAELNSSRSYDDHGNRRLAVIIAVPIASIVWLICCCYCVRKCCCQESRQNVIVMNQNTPAAPAAAGPQIILQQPIVNQNVMSHPPQQAPPQYWQSQPQQQQWAPQQQQWAPQQQQQQWAPQHHEFSPNAYSNPNFTGPTAPPPYNPQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUS0</accession>
    <name>A0AAV4SUS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_89111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010268">
        <property type="protein sequence ID" value="GIY38168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12142" checksum="8546146C7D85FF3D" modified="2024-11-27" version="1">MSAHIYGRKWNYDLPTRRTDDRGSCQSSPLFQISRQTRSAVNQSFTLDEHVVRGASFTRPSNVDVKHVIKKRNPPLRAVLIAPLYAGRAIRATLIGRPQKAEQFIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY90</accession>
    <name>A0AAV4SY90_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Pars2</name>
        <name evidence="10" type="ORF">CEXT_531701</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01010460">
        <property type="protein sequence ID" value="GIY39403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF10">
        <property type="entry name" value="PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY39403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="317" mass="35821" checksum="9E7AF896FE589971" modified="2024-11-27" version="1">MNKVNGQKVSFPTLIPESLMKISGRWEGNDNLFKLKDRHSSSFCLGATHEEVATSVMSNNIISHKTLPLCIYQISSKFRDEMNPKLGLLRGKEFLMKDMYSFDSSEENSLLTYESVCRIYHEFFHILGIDIIKIFLYGEIIECYEILYCPKCHSGINKELHGTTYSAPFQKAKFDSSKGGSEILHMGCYGLGLSRILAASVEYLSNANSIRWPFLLSPYYVSVIPPKKGSKEESVRPFADSLAESLNKISWLNSNVIIDDRTNLTIGKRLNEVSALGIPYVVVVSKPALGDIPQLEVIDVYKNQTTFLSHKETLEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCJ6</accession>
    <name>A0AAV4TCJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_112781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011055">
        <property type="protein sequence ID" value="GIY43909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13797" checksum="2D224290D365FD10" modified="2024-11-27" version="1">MTVNIKIVALRIRTRPLQEINHRGNWERNHAKSSPKRAAIFGNPLIGKEERANFLPSTWVNYFTPKTHYKVITIALLQGSLNNVTSRIVFRLISFLSQVHCSLPFKRVKPDRIMGDMSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJG7</accession>
    <name>A0AAV4TJG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_427071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011211">
        <property type="protein sequence ID" value="GIY44915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10123" checksum="3D0D630C89C15AFC" modified="2024-11-27" version="1" fragment="single">MASGCTLAPETQAAVSCGAEDVCQMITRCNVWAWGAGALPRWKRGDSLPQPLSVGSDLGHHGLLHRMNIFQYHAFEAALAPICADVNCHNPYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNQ2</accession>
    <name>A0AAV4TNQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_19701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011524">
        <property type="protein sequence ID" value="GIY47121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8499" checksum="9D9E27BD9D60B3ED" modified="2024-11-27" version="1">MDPPIVRQRIPMEEPVVSLYYVTSYDATLYGASCGMPKCSCDVKYPMVYSMVWILLSYAKGFLWRILWCPYAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRD4</accession>
    <name>A0AAV4TRD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GLTSCR1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_265293_2</name>
        <name evidence="3" type="ORF">CEXT_992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011563">
        <property type="protein sequence ID" value="GIY47307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015671">
        <property type="entry name" value="GSCR1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15249">
        <property type="entry name" value="GLTSCR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GLTSCR protein conserved" evidence="2">
        <location>
            <begin position="621"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY47307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1128" mass="124241" checksum="DA46947247A9D0AD" modified="2024-11-27" version="1">MGANQGLQLQPIQTASGAVYAFAGQTITVPGLPTALSNTQLAPVTVPMHGVMTSQGMISGLSLQPQAPQSALQPQQSLFGTAVPFSNHVEQPSQVIQVPQPLAAPQQVATNHQSHLQNQPQQIEHSPVSSPQKPKVPTLNLEKLMKESGIVPSPESQIIQSPDCNSPVVEEVIQSHLDMNSSQLITALQSSQQVILEQSPGHTVIPQLKLAFGDGSVILHQPATLNNNSRLQHYISSGQIHGRTVNTTVGSIVLTSSASTSVVSVPVVTTESTFQNHSTLISRLNAAPVISVPDASTLAVTTNIVTSTTNVPLTVQSLNDGNPSSYVVQRTNTLTSTSDRVFVSETVLATQTHTTPVISTSSSIQNVQRINHSNPALQTIIVSNEHNVRTVPQSSHTVLVSTLSSQNAQPVLQKYGQQDLKIQEIIDSGAVVPNHNHPHSSHVPNTVSNLLEKIQKEITELNFVKNRTPEQNKIFQLLQQLKQKNCTDGSSKSFCKQRVFSTVDAKNPALTVQQQSGQLDKSQHTNSKPLASRSLQLVNLLKQSPSHIPNQAIAPSQPRLQTSHNQTKTSNEVTQIIVRLQKPVQQQSVIQPPPNVIQRKAPSPVKRIVNTALINEQLKNDQNGAVNPNMKTPFSSTIDACCRLIKYHVYNTTDSSPFELAEAETAFQSTSVSHMDKIKSLKDRFNLAQMKSTMKPVPTSEEIYIQRLLIDEEQEALKEDKVAVAEGRELSLSLARQQWLYKVLHSPTPERPTSPDFEIQEEEKTCGDSCRCRDDYDPPNAEYSDPVYKDDDNLEAPVIDSCADIVVPQHNDNCDRSPPTLKRIVTKPIKFTESDPEDQIPARKRVKFNNNTVFKNEASVLSHDKPIISKYNDNLPKTNHKYPMTFQSESSLSDVVSDAELRKEFSMSPMEMDEAHIDSRLVNLDSSSEVNHLVDFEPLIPGTGESCDSNTLYNNSLRNNCVNYMLNEDWPNEFAHQPTELDIAVANIEGNHNNPAEIDLSGLAGLDAHFNNSQHCIPNGIQDDDTSVEMNLIEYRIPKQQKRYHDSSVQSVSNCSDMGDQTHSAIKSIIDPESRYDRISTEFMSLNRHNQNAHIGGYSSSASARNMGSTSMKKEDRNLDEAVRSILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TV00</accession>
    <name>A0AAV4TV00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA-splicing factor CWC22 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ncm</name>
        <name evidence="8" type="ORF">CEXT_470661</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011950">
        <property type="protein sequence ID" value="GIY50168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TV00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="665"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="625"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="865"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="625"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="878"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="915"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY50168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="926" mass="108702" checksum="8F44EAB3F7FF81F5" modified="2024-11-27" version="1">MLSHASLLDNPKLMNSKRSGNYDDYIQYKKEKTDKIDKRNEKLDHKDDYHIESKGKEKRKFDKKNKNLDLESDYHHTELEKVDKNKYDKKLNKENSDYNFEYEKRESSNKYRQESKRKEKKYENFYNNEEFDKHRKEKRDKFDNDKKLHEKIDKHKYDREEMETNDKNFSRQDLERNSSDVESDVSEDHVKSDRIRSAVQRVENKPRDNDSEQYMNNDNIEKEYHSDSRMERSKYKHKRSEEYEKRKRRNEYTNQQYETYSNKRKRDLDFEYENNDFNTERSNYDSKNSRSERSKEKLRHDTNRQSDQNKIDSMQSKEILSKADEKDLEKNTSTNATEDNKDSFEPLSKRQKIENINMRTGGAYIPPARLRMMQESIQDKGSEEYQRIAWEALKKSIVGMTNKVNSSNIAEIVPELFKENIIRGRGVLARAIMQAQAASPTFTLSEIGELILKRLIIQYKRGFRRNDKTICMTASRFLAHLLNQEVAHEVLILEIVTHLLENPTEDSVEISIATLKECGKKLTQLTPRGMRAITQRVRDVLHEGKMDIRVRYMIEVFFAVQKDGFKDFEVVPPELDLVEEDDKYTHLINLDDAIDSQDLLNVFKFDPGYIENEEKYKSVVNEILGEDGDSDEGSDESGSEEDEEKEEDKEDSQQIVDMTETNLVCLRRKIYLTIQSSLDFEECAHKLLKLELKPGQILEMCYMILDCCAQQRTYEKFYGLLAQRFCQLNKVYIEPFNEIFENSYKTIHRLETNKLRNVAKFFAHLLYTDAIPWLVLSIIKLNEEDTTSSSRIFIKILFQELCEYMGLPKLNDRVKDVTLQEAFEGLFPRDHPHNTRFAINFFTSIGLGGLTDELREHLKNLPKNPIPIVPTVVSPANSSSSDSSSSSSSSSSSSSSSSSSSSSSSSESEESDSKKNRKKQQKRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TXP4</accession>
    <name>A0AAV4TXP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_809121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012052">
        <property type="protein sequence ID" value="GIY50959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TXP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11103" checksum="B537EBAC5FEE0D8F" modified="2024-11-27" version="1">MIRLTSPLLLPGIFKCFIGLGNGSICIFYCLRVVRVIKLKITREKDVLVVYVSYHGLASLTSSRIKNGRLSFRVNFSRPTIVHCRDGHKETKSSHLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZ20</accession>
    <name>A0AAV4TZ20_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_23046_1</name>
        <name evidence="7" type="ORF">CEXT_644021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012013">
        <property type="protein sequence ID" value="GIY50707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZ20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY50707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="449" mass="51638" checksum="3472D8FEB2DBA45D" modified="2024-11-27" version="1">MVEEEIDSKIQVMRLKYLKSLNEISAIADSSQFHLMKFYSCSACSFESNHKYNTQMHIEKAHKNSNAEVNKVLRKMDLPELATSNMDDNSNDSLKVSEESSNSVKRYRCGFCIKKLPTLQELESHVESLHPVNEEAEYSYYFTPDIKSIFMPDDKELFECSYCKSGKANLHSLKKHSDLMHSESQFKVRGYVNRSTTKAGVDSSIIACGYCYQRLDNKNELKRHIKSQHPSLPQKSIGGFKNCDVLKKSLEEFGALPDKKVKLGSLAFVCSHCGAAYSKPEQVKRHCLKVHARLKPEFLTINTVHTNINFYKCEFCQFTAEKHHLDLHLENKHTMRVICGYCNRQFEFATKLREHHDLVHKGLPVKYSQETLDKKKILPKSAIKKEQVEIKSSQKPLSESFNSIKDPDSVALESIFTYDHSEGCRKISVLSFSRMHNIFPKVLLKDVMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U0J6</accession>
    <name>A0AAV4U0J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_479281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012091">
        <property type="protein sequence ID" value="GIY51299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U0J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14433" checksum="736E558D49CA4E25" modified="2024-11-27" version="1">MISALYSGMVKNDSKLYFQYLLEQLQKSVNGWGTHWVSTSPPTPTLHTFKTERIQLFEMHLYDWWRQDSRALLVKPGCLVRAPTRRANALLLYHVGGLDERLPTFTFLKGWRRKKKILNSSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1J1</accession>
    <name>A0AAV4U1J1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_429121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012137">
        <property type="protein sequence ID" value="GIY51663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043808754" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12068" checksum="CE1540ED3937A791" modified="2024-11-27" version="1">MKPPGCKTKVVLWAVVNALLSVGDGGHPSRCEIWRTDIVHSEAVAKASRSFKGLWVSDKGMAGPVGIGQVSLSHSLLGVLSALSYLLLREFQLGFFRYRQLIIDWRHCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2R2</accession>
    <name>A0AAV4U2R2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_491601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012192">
        <property type="protein sequence ID" value="GIY52083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2R2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17763" checksum="A33650D62D20A1A7" modified="2024-11-27" version="1">MLNIPVPAIHKSLQTYGHFAYKHSFNSRSDLLLFLANTAKILTVGQITPASLGNLSFCRGISTLVLFPILLLLLAQPPLPSPIIRSNSVPEDTLVLLKSVARDSAKGELHYYSSHPLPKTTKAPNPLPPMHFSRKQWLRSIIFSLSRFLRDDEFNFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9Q1</accession>
    <name>A0AAV4U9Q1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_230521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012515">
        <property type="protein sequence ID" value="GIY54474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9Q1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14167" checksum="8FB5CD4ED2E36913" modified="2024-11-27" version="1">MLGMSTTNPYVENPTFGQEEGVTPFTDTLSSSKYMGGFKLFIVEEELEVINPESQTFFRYRSIEAKKHAADSTYWNKKTIQCLARDSKSPRDLSVLRKIIRTSIRSDVASPRKKKKGRNERRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAT6</accession>
    <name>A0AAV4UAT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_375171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012560">
        <property type="protein sequence ID" value="GIY54868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="31148" checksum="D03BF837711122E5" modified="2024-11-27" version="1">MDTNECNVIVAGQLFIRCLFTTWYKKFTNVGVKNIEYDGEDLSTLSVKLIFIVKDYITYFRNNALPLVYQLPITILTEPERFMEFAYSVCKRLYNKPNWESKVQRFFLNSVFLFDILHQFQYISCHRVANAVPELMFQVFKDTHLQVNSNDGGGLSALRIYFDFVITNHPWRLSTMSDVLSLIGDAILKELEILKQSEQRNPTINNMMHMTLMSDMHRIMGQPPLLNDNVCPFCQCQCIKNYWIFTKCPNIEKLTLMEKFLLRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCF3</accession>
    <name>A0AAV4UCF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_733271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012627">
        <property type="protein sequence ID" value="GIY55290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="6221" checksum="0F5ACC94DB724CAF" modified="2024-11-27" version="1" fragment="single">MDTKSLKEEDVKPLKAHPGYVYLKCTLDPCPKILGHPVRVYDLDKAVINVVQNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UI51</accession>
    <name>A0AAV4UI51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_245944_1</name>
        <name evidence="1" type="ORF">CEXT_68661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012919">
        <property type="protein sequence ID" value="GIY57520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UI51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14615" checksum="D85A9B896F031618" modified="2024-11-27" version="1">MHHSHAMMKPEKSCSCSLHVGQLTVYKHTDMRSSYSCDDVKDCNSFCTNLVITEGEVHHAIMAFFFSSHLQKQNVSREQRTAIFLHIMVARQEKNESQLKLAIICFNKDPIFLQQIGSNVFRRFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUM2</accession>
    <name>A0AAV4UUM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_181771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013488">
        <property type="protein sequence ID" value="GIY61581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12334" checksum="D9864BCB494728D4" modified="2024-11-27" version="1">MIGELEGKEEDSSRSSVILGAGTLPVSAAVAQPGLTQFTANAILAAVLLVKSRCIWATEAPTVVNISMAKMLNNIMNDQPLLETGSAMCHSEIEPRNLWSASQSQLEPHPKLRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1R9</accession>
    <name>A0AAV4V1R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_246011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013801">
        <property type="protein sequence ID" value="GIY63905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8340" checksum="EE8AED99206677FC" modified="2024-11-27" version="1">MTTERSSCSRLGSEEISWLSGGKNVCVTSKPSEMSSKHQVYNRIICSMRTRIIAFQPLTYKTHSRDENVKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V207</accession>
    <name>A0AAV4V207_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-directed DNA polymerase from transposon BS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RTase_42</name>
        <name evidence="1" type="ORF">CEXT_4311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013795">
        <property type="protein sequence ID" value="GIY63873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V207"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14695" checksum="9DA40F43BF69E006" modified="2024-11-27" version="1">MLFSLFLLEEKRRCKVGIFADDVVLWHSDIKTIEADINFPLKYVSDFAEEHKLTFLILPNRQLVFYITTRHIYNYQPTIIMKGQALPYEKHTKYLGFTKDEEFLSSRHIKFWEAEVGRRQMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCB3</accession>
    <name>A0AAV4VCB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_228981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014263">
        <property type="protein sequence ID" value="GIY67629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9901" checksum="39179FCB54D1DA24" modified="2024-11-27" version="1">MHHERKQKNNKGCKQNRHAEKRNKTQINKEKMKRKNLSVLERGKRTSNLADLFFKVDVSSAQLQVVYAAEMGQVLFLSKRNMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDC5</accession>
    <name>A0AAV4VDC5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_74501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014373">
        <property type="protein sequence ID" value="GIY68406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF209">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY68406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9059" checksum="75D7F061B63319E5" modified="2024-11-27" version="1">MPMNYSFNTREDLGFRLVCEQVSHHPPVSAFHAESEDFQFYGNIHPPQVLGEVPRDKTGRNAHCASPQVRFRFLYSYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VE93</accession>
    <name>A0AAV4VE93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chaperone protein dnaj</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_358041</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DPH4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014339">
        <property type="protein sequence ID" value="GIY68204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VE93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45255">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45255:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="50"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="DPH-type MB" evidence="6">
        <location>
            <begin position="124"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY68204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21662" checksum="ACE7D2C46CC8CA35" modified="2024-11-27" version="1">MGSSQTLLLSTPEKIDNFHSQLACQRSRCTPESCARRGNGHICRLYTMENYYKVLGISTNSSREEIKRSYHNLIREHHPDKSNDQASTHFLLIDEAWKTLSVDNLRKKYDAELLALELQDTHPVQEEINICSTFYNSKLEQYEKDCRCGGKYILSTHEVIKDELLLVDCDNCSLSIVIDCAINGENKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEM5</accession>
    <name>A0AAV4VEM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_15431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014296">
        <property type="protein sequence ID" value="GIY67935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="23482" checksum="C96CB7EC016E67BE" modified="2024-11-27" version="1">MRDSTSIHNLGDRFRIEMDSSCPSSCIEKGSSSLEKQHSSVLLKGFNERTLPEEPLFGLRSSSGFSVKGVNVTFDSLDRCRVCFAFEPEGVYYVARARDKMVGPLVLCMDCESSGGNLEKQHSSVLLKGFNERTLPEEPLFGLRSSSRFSVRGASMEGSLEKELLILRFSVGGKCDFGPLGLLLCVFCVWARGCLLGCRRKPGIEANRIFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJU7</accession>
    <name>A0AAV4VJU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_441831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014661">
        <property type="protein sequence ID" value="GIY70421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14062" checksum="5CCF761B875AB9CE" modified="2024-11-27" version="1">MANVTNADVITPTRILRKAFTAMHTFVWFFASVSADGIAQGETLSECSVTKMARIWSSHIGDDVRVIQDNLSERIALDIYCMYIIFLRFSNRRIQVLFKYTRIFIQHFVWCMFIATHTALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLA2</accession>
    <name>A0AAV4VLA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_447621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014697">
        <property type="protein sequence ID" value="GIY70621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9408" checksum="4B34A6D0E5E2D126" modified="2024-11-27" version="1">MLFLPSYPPCAIKTEQLHQECRDPFVCEESTLHSNFTAVPSRCSIIKCVLATWTYIDRWDNRRGGSLSIHKAWLDDVGRAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VM05</accession>
    <name>A0AAV4VM05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_316331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014738">
        <property type="protein sequence ID" value="GIY70955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VM05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9999" checksum="F92FB6B8EA864C27" modified="2024-11-27" version="1">MQTILFRPYCVPLTSLPVRGGIGTRGRGCFLQPLGRGSALALIGERKTRQQSARMAPFLEFALHDTEPPFARNGSITPRAMISHNCDRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VQJ7</accession>
    <name>A0AAV4VQJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_791591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014894">
        <property type="protein sequence ID" value="GIY72076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VQJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9461" checksum="2B9AD9B8C366B4CB" modified="2024-11-27" version="1">MPYLDTMKEEDDEKNNDEEMIRKMKFGFGMIPKRRCPSCSPFRQTAIKQTPWHYQRSISLKGKVSENVIGNLNVPQNVTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUB5</accession>
    <name>A0AAV4VUB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_322701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015133">
        <property type="protein sequence ID" value="GIY73856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="20795" checksum="773A245614A12608" modified="2024-11-27" version="1">MKIRENNNRINFLRSQKPLSRHGNSGAIVPRFGQKFFGHVYLGNNQNSLKSIAIPCAPVHFSCISMNSHSQNQFPSVLKSNFLAMAIRSHCSYDLPKVLRLPCLSGKQPKLIKVDRNPNQFPSFLKSHSLAMVIPEALFPVLPKSSSPPCLSGKQPKLIKVDRNPVLTCAFFFVFYEQPLSQASDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W311</accession>
    <name>A0AAV4W311_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_751221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015580">
        <property type="protein sequence ID" value="GIY77107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W311"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="275" mass="31424" checksum="F4B02775842C88A4" modified="2024-11-27" version="1">MATLKVNDSSAKKIYVENVLEELEKQNYVNETFDEMLTYIRNRPSYKRMKQVAVAHMTNKLKSSSGTPDEGDCDETRKQMKEVSNLVLSLYNSANKVISDTLEHKTKNAITKALKRLDKQTSTTKLTNNRTAKRKHLNLSECVDKRSQKRKNSKVDDCDSEFSRSSFPADGKSDISSIDNLIVVSEDEELESRNSLDICDQMSEDSHSNVHFIALKKEKGVKEKRPHLFLTMLRGFIINEDLAGTLSSTSTKSTERMKRERKPSTKYFSSDYTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWW4</accession>
    <name>A0AAV4WWW4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Nuclear pore complex protein Nup153</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">153 kDa nucleoporin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Nucleoporin Nup153</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">CEXT_739951</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the NUP153 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016917">
        <property type="protein sequence ID" value="GIY87282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.10:FF:000001">
        <property type="entry name" value="Nuclear pore complex protein Nup153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026054">
        <property type="entry name" value="Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193:SF23">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="13" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="22">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="22">
        <location>
            <begin position="603"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="22">
        <location>
            <begin position="658"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="22">
        <location>
            <begin position="852"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="48"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="139"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1117"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1219"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1306"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1485"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1546"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="1228"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="1547"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="21">
        <location>
            <begin position="1559"/>
            <end position="1572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00060842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00068609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00078197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00079437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="GIY87282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1572" mass="166851" checksum="649AF960F2CC24E8" modified="2024-11-27" version="1">MDRRALRNKKSKSRSARPYDRPNQGILGKVASKVKGLFNPSWISSVSQWISPSEEQTSSPNTPEEESADEDVAPQTSSITSTSRGSKRPRLRLSPTLNEETQTWLETPPSSSLFSQSSHLPSTVTQNILVENKESSVIMNGDDHSENSEGSASTSGCSSLVSSHKERSNCLGPSSLRLSNDRILANLRGKNTINLKNRRDISSRKEGLSPNVNTSRMSTWSGSAGFSPTSNFLRRPPSVADANQPSFNVSAFATPSKVSPQVEKKVSSPFYQGRTTFGGASSSRRMPVSTAPYQVERPPRNQIKIRTNQSEDSLEGMSSAAKRILLTLEKMMQKKMPNTNRSPVDLSLYLRPPKHRSNVVSTPVGTLKGPPIANISTISKLATLKSCRVKRFHNSTMRKKVIPDTSTQSDIFQIAKDKGGGKITNKLNQQHQKRVASSSLEQLEVSLPNVPLPITSLPTFSFGPKIDKKIDDNKVGSDFVFSSPIEVLPKATLIPIHKNVAISNFESYAQNSKNSSSSPEKQLFTFSSPIQHEVPSSISSTNFATAAATWECSSCWVRNSINETICLACTSARISSRAVELKSSLSTPSTKPLSGLFGSNLKTPSLTWMCDACWVSNPLKEVKCLACEAPKQELKISTPVICSAVPSIKASTTPSSKSTGSSTWECNECWVRNAEKDSKCLACETPKPGAKVSSTSTSSGSFVLTGSGFKIPEFTSTSSQYITFGGAKLPSVLSELEKDKPSGKKNLSDVFANKLSETSNTSTSSPQTSSDMMKKTVSNLKNTNSDTPRINGPIIVSLDTKKTSAAEGFSFCSGKDKTNVTSGFSFKSNTTSAETSSGTPLFGLKLLSTGTPTSNWECDTCLVRNSSDKLKCSACETLRPSKGNMTGLKDPESFKFNSPLQSSPITFKFNSLPSTSQTATTATSFVFGSTTSSTSSFLTPVSSTVSNVTKTSEEPKMTSLIEPSIPKPSVPEYKFDTPKIPSLDATKNTNISIVDLKNEKSDKSSFSALPVSKSSNEGSTTSIMSSSIGSMFKIIPSEGSTGFSTTASVENKWPLSLPTKVETSTAANPLLTESKLVSENVQPSQSKDVPVGGFNFKAPSSTSAIFGGFSTPTSKIDNKDASKSDSLAPSSELKSEGFVAEKKTDSPFVLNTSSSLSSVFTLPTSPLFKTTDKLNAPKSTETPLMKNILTSSTVSTATTAPFNFSCAPIPLSSLANNPTTQSNLSLTSGSSQPVSISQSQEVKKTLNPVAPFTAATTSSTFSFGSSVATTTQSSPSSGFSFFPSTAANTPASSSSSLFVFGGASSSTAQTSKPGGFVFKGLNEEKPNPASSNSLNFNVPTTTTVASPVFKFNNAPSGNFIFGAVKSEPGTAKAVPPTLSSIPPPGFPTNPSTTPFQFGGQSTGSSAPVAPTPAVAPAFGASTFTFGKSEATNQLPTTQASTSGFGVSAMQPMFGATAPNFAKAEKPAFNFGIPQGSNTSSVFQFGEKKQAQSAQQIPASRFPRFPSFPPQEAPASVPNSFASQFSFNATPTFNFGATATQAGPFQFAASSESQSSSAPRKIRKAVRRVPRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWY6</accession>
    <name>A0AAV4WWY6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_223121</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="BPLR01016867">
        <property type="protein sequence ID" value="GIY86996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY86996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14873" checksum="6A6735AC892A55E8" modified="2024-11-27" version="1" fragment="single">SYEKSLTTSPVIFPSIIISYILFVTWIGPAMMKKRKAFDLRIIMVVYDITEVMINGYIAYRLFGLIRQHQYLYCLAKNNPSYSSVVETVMIFGWSVFLNKMVELFRYNFLCVAKETRANYFSSRCPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZ27</accession>
    <name>A0AAV4WZ27_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_779321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017018">
        <property type="protein sequence ID" value="GIY88077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZ27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="20716" checksum="6B1E86A759AA44EC" modified="2024-11-27" version="1">MNSKSYESGRISYRNDVYDPNVRQNAYAVDEDFIVMAHLIIPYLIKPGLLTDILRKNEKYLNEKGKISSFYSNQLKSPNTKLNNQRTHLHVTYLLERAHLISQNDKQRVESALCFRIREASLTCFSTARIPKSIWNRFKTSPEHEMPRPVLFGKYLILNVFARHLMSRLTTACGLPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9K3</accession>
    <name>A0AAV4X9K3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_136621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017337">
        <property type="protein sequence ID" value="GIY90646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9K3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY90646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="7964" checksum="22C01445BED285A6" modified="2024-11-27" version="1">MFPKISPHFIPLSARPIIGSSLDPSLSPGQSNNSAKSRMHSPIVEGSQFHAPIDLLGELKERLACLTISHFNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCA5</accession>
    <name>A0AAV4XCA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_229401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000127">
        <property type="protein sequence ID" value="GIY92323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="16497" checksum="53FB30373E141B4E" modified="2024-11-27" version="1">MKNNISSNQTLTCCRGRALYGAGADAGSTGETMKEGSEETVGTGAGWGLSRTGCSTPQTGIVGRRTSVDLVFFNVIFKGTVYPPREFFPPRFLDDGGCYRSRLSYGLGKGSNPPPSLQMPCPASINPFLFGYNYRISSQSPLGLHSQNLATKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJT4</accession>
    <name>A0AAV4XJT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_602591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000508">
        <property type="protein sequence ID" value="GIY95352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10712" checksum="2550F71FA48C952F" modified="2024-11-27" version="1">MFPGGPPLVYWPGHIMFPSGPPSMYDKITRCSHVVLLPCSEQATICSQMVLLPSTEQAKNGPRWSSSHVLTGPHDVRLMSYVYQSFYYWLMYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLQ3</accession>
    <name>A0AAV4XLQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_581621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017811">
        <property type="protein sequence ID" value="GIY94653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8351" checksum="4011991975CC840F" modified="2024-11-27" version="1">MDGRKEERTDGWKKRKDGQTGGRKDGWNEGRTEGRKEGRMKRKKECRKEGITEGRTEGGTEGKKERRKEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNS8</accession>
    <name>A0AAV4XNS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Disheveled-associated activator of morphogenesis 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DAAM2</name>
        <name evidence="3" type="ORF">CEXT_625811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017918">
        <property type="protein sequence ID" value="GIY95464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014767">
        <property type="entry name" value="DAD_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51231">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAD" evidence="2">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY95464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11917" checksum="99F1E5CF721B4EA7" modified="2024-11-27" version="1">MLEKTHIDRSSKESGLKGSSGVRNGSINGLRAIKAGSEKGEFDDLISALRTGDVFGEDFTKSRRNRRKGSQTMLLHQSSSSNNENVQWRSIPRESSRDRVITPKLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRH2</accession>
    <name>A0AAV4XRH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CABIT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_93861_1</name>
        <name evidence="1" type="ORF">CEXT_3521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018151">
        <property type="protein sequence ID" value="GIY97329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15297" checksum="1940E2AD141A55C5" modified="2024-11-27" version="1">MSSLSGIKCWGEPLPPQEFLRKYGLPQIVRVFEGNRVQGPARVDLDRPLLLYKAYICQQVHARSIDRDKNGGITSVGPPLILPDTYPEVKYRYSIVASLSNTNLTFFKFVLSLDKFEKSFGYRSIRIKLNISRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XS86</accession>
    <name>A0AAV4XS86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_436351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018079">
        <property type="protein sequence ID" value="GIY96709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XS86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11277" checksum="0DD9B72AFD4D4062" modified="2024-11-27" version="1">MELSKSKYHSRLCQSLRSRYVNESEFEVVMRSVPLRMDLDSRSSLVLQETKKQKKKKRQPRQCQCRRESFRERLISFVITAYIMLDLVRTSSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU85</accession>
    <name>A0AAV4XU85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_765591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018327">
        <property type="protein sequence ID" value="GIY98707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8065" checksum="778232125E149392" modified="2024-11-27" version="1">MSELNFDLGISELCLRYGLRLLQNAEYIVDARTGPLKHKFEKRSIGSQYDAKFGRLLAQMCKTDSINPDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUR1</accession>
    <name>A0AAV4XUR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Laminin subunit gamma-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LanB2</name>
        <name evidence="10" type="ORF">CEXT_83651</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000822">
        <property type="protein sequence ID" value="GIY97711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009888">
        <property type="term" value="P:tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000051">
        <property type="entry name" value="Laminin subunit alpha 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000067">
        <property type="entry name" value="Laminin subunit gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000105">
        <property type="entry name" value="laminin subunit gamma-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050440">
        <property type="entry name" value="Laminin/Netrin_ECM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574:SF406">
        <property type="entry name" value="LAMININ SUBUNIT ALPHA 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574">
        <property type="entry name" value="NETRIN/LAMININ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 6" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Laminin EGF-like" evidence="9">
        <location>
            <begin position="75"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="9">
        <location>
            <begin position="130"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="9">
        <location>
            <begin position="186"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="9">
        <location>
            <begin position="234"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="659"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="291"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="437"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="787"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY97711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="867" mass="96633" checksum="B32C6832747E9783" modified="2024-11-27" version="1">MQNIVILKLDVAYEQLKIVNHVHVLEMVLVLFYLMKKWLVLECPEGYAGHRCDLCIDGYYAESTDPYGRPLCRKCECNENVDPNAIGNCDRTNGHCLKCVYNTGGRYCESCLPGFYGNALSIPKGDCKACNCYPVGTEKRDLNSEVLVCNYATGQCPCKSNVEGKHCDTCAEGYWNLVSGEGCEPCYCDPVGSLNRTCDISTGQCNCRPGVMGQKCDQCMSLHYGFSLEGCKQCECDQIGSFSLQCDPYGQCPCRPNVEGRMCDRCRENTHNKAAGCINCPPCYNLVQDAANIHRAKLAELEELLKALKENPQLLNDEEFVLKLKQVQDKVDKLLEDAMSATDLDGKVGSNLKDLYKRLEDVRKTMGVIASKMDDAREIGQLGERNITIAEDIIKRALDALNGARKFLETEGISALEKAIERSDKFGQQSVKMSEIAREARHLADEHEKEAKEIEDLADEAKKIAQEAYEKARHALETPGETADNINRLERKLLDVNFMLEEVKKLAASAKEEANKTYEGALDLFTKANSINLPDVDVELMKKTAADIIEEAKKIQNQADDILNEHQELLDKVKQQIEDAEDLLKAGEKQQQTIDEMLATVDAALAKAKEAVAAGEETLAEAKETLETLKGFDELIRESRGRADEALTRIPEIEKLITEAEEKTHSAEEALRGAKQDAVESRDEAQTAEEKAEQASKHANDVLEGAEETKAEATKLRDKADDLAEEVAETEGILKEYEDQAKSDGDLASQALEQANQAKTSATDASVKVKNALDTVEDILRALDGLDDIDESLLDQLEQRLEAAEKDQKEADFDTRMGELRQARDLQNQWMKDYTEEVERLKKDVANIADIRNALPDKCYRRVVLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX43</accession>
    <name>A0AAV4XX43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018283">
        <property type="protein sequence ID" value="GIY98358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13112" checksum="810D5705368C780E" modified="2024-11-27" version="1">MVFVGFSYSIFLPYHCSLVQRQNTGFETLSGGSVFYPEVISCPLESIEKFQHYFVSTCSQWLQLNDNEAHRFMEVQFGYKREMAPALFGLGGADQEVGAEITWRSSLLPNEAERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1I4</accession>
    <name>A0AAV4Y1I4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_595551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001146">
        <property type="protein sequence ID" value="GIZ00311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1I4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9271" checksum="C53D1F91FA80DF90" modified="2024-11-27" version="1">MVMLFSQTLKTHARLFQLGLLENKNPQTDLAAFTHNCGSSLGYSHANSSPSRMSDCPRLLHDKGIRHSPPRPPPHPRASRRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2X9</accession>
    <name>A0AAV4Y2X9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_455601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018677">
        <property type="protein sequence ID" value="GIZ01503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8092" checksum="13192F428D3FD273" modified="2024-11-27" version="1">MDFVSEALRPLSSRWEMGSTQVGQERDSIHWHCPETLTQFRSLRKLKITLSSIASLSLVVVDETLSNVSEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y557</accession>
    <name>A0AAV4Y557_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_728661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018816">
        <property type="protein sequence ID" value="GIZ02477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y557"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16618" checksum="A4CF755CF1D1239B" modified="2024-11-27" version="1">MTFGEFQSNAYGVESILNTTALQPALSTGQGSFHEFCPSYSVWGNRLPNLLDIFPLNQPIWQRIFRKRTNEFRTIGCFVCKLSERGEGGSPGKGQGGGGEKKRKSPAGDFLLYDRRIYLSESRKTPKKMCPNKTLLTRNSKTEIAAQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDA7</accession>
    <name>A0AAV4YDA7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutathione transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_579791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily. Mu family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01019049">
        <property type="protein sequence ID" value="GIZ04209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF222">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="6">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ04209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="22481" checksum="0C24942122F5E1CB" modified="2024-11-27" version="1">MVKPVLGYWDLRGMCESIRYLLHYKNVDFVDKRYVFGQDEWWKNKFNLGLDFPNLPYYIDGDVKLTQSVAILRYLAGKYGMDGKTDQQKLRVFLAEQQSADFREKLRSVVVSDDYEKLKDGFIKNLPDAFNLWKDFLGDAILDDFPTLKAYHSRIKNLPELQDYFNSPTYRRWPLFGPMAKFGGGGDPPDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5A6</accession>
    <name>A0AAV4M5A6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_216304_1</name>
        <name evidence="7" type="ORF">CEXT_185511</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019413">
        <property type="protein sequence ID" value="GIX67554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5A6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050621">
        <property type="entry name" value="Tudor_domain_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948:SF29">
        <property type="entry name" value="FI02030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948">
        <property type="entry name" value="TUDOR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="6">
        <location>
            <begin position="163"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX67554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="36174" checksum="CBAD9337A6BD6BB7" modified="2024-11-27" version="1">MLNDWILCGEEFEDIENSYGVLQRRSICGNSSESAVKPKDESYICRYFSLRGYCPKGSNCTYKHISLAEGGVTRDQEETFALEPTLMLPNPSSTVLVQVSAVVNPSLFYCILPFGNKTVDEVDSLVSQGHIKDVWVKDEMRALFRNMRKHYENAPFTENTTVALSYGSIVVAWRRVDCCWHRGRVLDVSDVAGPTRIFFVDFGDEDWVPRKKIREILPQYLCTPFQAIECHLSDVEPLGFEIGNKWSLGAIHCFKKLVASEVLLAQVTYRCGHILHLTLRKTNKEDKRVIGECLVKEGFAQYISFAAFKTEEASVYVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MF35</accession>
    <name>A0AAV4MF35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_581961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002127">
        <property type="protein sequence ID" value="GIX70272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MF35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13303" checksum="54FC77A8A35B7215" modified="2024-11-27" version="1">MHPSFLWHLISLIRILEGGRKSIRFWSRVMNSATFLRHPITWAAIPTANPTPDLLSVKTHCCYVNDSSLLKLLTFNVSGFPQTTREKFFNSASFVLLAIQFIPCHRYFLAKLFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MF72</accession>
    <name>A0AAV4MF72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019722">
        <property type="protein sequence ID" value="GIX71107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MF72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9926" checksum="102295B6C89DC334" modified="2024-11-27" version="1">MNENRLWAKRLFPLGSVRELLKQMPQVTRRRSQEVMPTHPLNGPFQVTENKICFSPEERETELLSFTQPKTGFFFFFFLITFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGI1</accession>
    <name>A0AAV4MGI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_458951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019708">
        <property type="protein sequence ID" value="GIX70998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12731" checksum="98542F895549BDE2" modified="2024-11-27" version="1">MYNYAAMDMHIMRNTMFESSNDVDREAVYILDPPITIPASLTMTTFAALHTKNINIPKRNCVEGAPVFVVIALLFPAKEAFISRRSIRTYYKKGSKIPYIQKMMLFQLCAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHQ6</accession>
    <name>A0AAV4MHQ6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Venom dipeptidyl peptidase 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DPP4</name>
        <name evidence="18" type="ORF">CEXT_746501</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endomembrane system</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S9B family. DPPIV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019707">
        <property type="protein sequence ID" value="GIX70976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000003">
        <property type="entry name" value="Dipeptidyl peptidase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.30">
        <property type="entry name" value="Dipeptidylpeptidase IV, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050278">
        <property type="entry name" value="Serine_Prot_S9B/DPPIV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731:SF200">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 10, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731">
        <property type="entry name" value="PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Dipeptidylpeptidase IV N-terminal" evidence="17">
        <location>
            <begin position="154"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="16">
        <location>
            <begin position="597"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIX70976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="818" mass="92929" checksum="C5114485CFAD0053" modified="2024-11-27" version="1">MTANNAKLNPRETPTQNSNAALQPQQESLELAASGPDQKNWRGIGIALLVIVVVCALIVAAIVLLTPDTSKTPLGDRGFNINKSRISLEEVVKGQFSYRRYNGTWISDHEFVFQDAYGAIGIYDAANNSEQVIMSNTTFRHYLRQYSISQYSLSADRQFLLLSHKYERIFRYTFKAAFLLYNISIDFLTPLFPQTPDLLLEYAAWGPTGNQLVYVLDNDVYYMSDVTAKPRQLTKSGIEGIIFNGIPDWVYEEEILSTNNALWWSKDGKKLCFASFNDTEVDILQYPHYGSYSDVNNVYPELMNLRYPKSGKTNPNFTIWVADLASTKELSKVQAPKEYKNFLMSTISNVGNRNYDFYLDIMLVSLIFYNYQEDSNGHGWVDLSTKTVFSADNKKYFLRLPGPPEGHLGRFRHIAEIDVKNGKKTFLTHGKFDVAYIIDHDANKNILYYITTLEGKAGERHLFSVADSSHPKPKQTTCFTCDIDPQCLYNDAVFSRNLTYYVLECLGPGIPRIELRLTATNKIVSVMDTNTELQELVNKRAMPVIKDMQIPIDGNYFANVRLFLPPVLREYEITKYPALIEVYGGPGTQMVTEKFNVNWGSYLASKKNIIYVNIDGRGSGFQGDKILHELYRRLGTVEVFDQISVASYLKEHVSYIDGKRMAIFGWSYGGFASASALADDETVFNCAISVAPVTSWLYYDSVYTERYMQSPSPKDNLINYEKSDVMNKASNFKGKKFLLVHGTADDNVHWQQSMMLAKALTDAGVIYRMQVYPDENHGLGHVKLHLYQTMDDFLNHCYSEAFRDDSSVSQSASSDSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIM9</accession>
    <name>A0AAV4MIM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_36151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019689">
        <property type="protein sequence ID" value="GIX70649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="21466" checksum="20B3BF5FC51B6C8F" modified="2024-11-27" version="1">MERHKSDARCEFSVQLIQCRESILRPLLISHVLFRSSSISDSNTSQGEIKHSQFLLPRQGGHFFLGSTLLTQPYYPSNPSLFPKFVHQCLQVSPNFAKGMSCPQLIFEGIYGRVSLVVLLPPSATHHFRLHCSSSKNANHLAHFVKDYHLNAPESDRHRLVVIAARLLGARPCVAGSSFHNHQRRVFVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPA6</accession>
    <name>A0AAV4MPA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spectrin alpha chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">alpha-Spec</name>
        <name evidence="3" type="ORF">CEXT_130891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002489">
        <property type="protein sequence ID" value="GIX74266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX74266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="480" mass="57044" checksum="8BE4698AE6539054" modified="2024-11-27" version="1" fragment="single">LVDASVNRRETLEEFSRLKEQEEHIEEIMAWIHEKKLYCDSEINCKDLSELLYLQKKHKSIGSDLKVRKEHSEGLNDQRLTKSFDSLEESWKKKGEQITFTVEAHQYLTDASECNRWISEKIHLLSSLDCGTDELRCEALLRRHVNVQNEISTDAIEIQRLRQEADKICNVSYNKPLYSENKSLLRSPMKTSQPRFDVLEDDPKSQSLTKAQIYDRQMQIESSFSELQRKCEERRQRLHYNCMYFRFKNGCEEMERWMRSKERIIDSNDFGKEADEVEKCFEGFITDLASHGLVIEQLKNLCETLEEEKSDHAQTASILFDDVYRRWLHLHDITSFKEKNLKGFTSVLVSQRICDDTIHWLMERCKIENYEIEDIKSIDTLRRRQEAMERELIPAEERVKQAHALADNVISSYPDQTDSIQRRISSLDNQWIKYQEKKIKERKQKLEESAGLQMFQNSVNTLVEWTNMMVRKIECKRKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQ57</accession>
    <name>A0AAV4MQ57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_718471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002460">
        <property type="protein sequence ID" value="GIX73970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQ57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8634" checksum="2CBEA57153C58F86" modified="2024-11-27" version="1">MTIHITPTSLLLFVLQQDHRIGPMRLISVIVQCKNIAQAREERIGIWHHLQSPMRRRQEAKINLPSPEGQPYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRP8</accession>
    <name>A0AAV4MRP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_657111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020131">
        <property type="protein sequence ID" value="GIX75070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10308" checksum="854495E86D47D2D1" modified="2024-11-27" version="1">MQASFLALSAELVPSKSLFPGPRPLSCPSLFDKFYAQLMFPLMVRARQENKHTGISSNIRRVSRILQRTAGQVYLIVAMTTAKLLFSEHLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUD5</accession>
    <name>A0AAV4MUD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_222111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002587">
        <property type="protein sequence ID" value="GIX75440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="47" mass="5257" checksum="9FC777DF0A06541D" modified="2024-11-27" version="1" fragment="single">MTILEMFVTSRSNKIRRNVALSLFPLAHSEPELNLHACHSGANHVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0A5</accession>
    <name>A0AAV4N0A5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_4471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020349">
        <property type="protein sequence ID" value="GIX77670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0A5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13177" checksum="DC1BFD74C9EBA69E" modified="2024-11-27" version="1">MTGSHRYVCSEYTPSFLDNSASDATAFQNAEISHHNFVDLFIIKLFFALLTVKMLSSFNLRNERSSLDIQEVGVSTSHGLSRGQLFTPSPRELASHHRDDHLHSSHSLFSLSSFFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7I1</accession>
    <name>A0AAV4N7I1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_730141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020589">
        <property type="protein sequence ID" value="GIX80378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7I1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9306" checksum="3A34D06080C7E3C7" modified="2024-11-27" version="1">MGARNIMCDACELSYEILSGIGSELVLSIQLKENRFDHTGVRLHPMRNSTAAPSKATDWLGMQIYITPSRFRLRYGTADRSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8C8</accession>
    <name>A0AAV4N8C8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_331291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020580">
        <property type="protein sequence ID" value="GIX80271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8C8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="44" mass="5036" checksum="FBABEF4781998B6D" modified="2024-11-27" version="1" fragment="single">GHWGVSWNSFTVKTTSKRVARLRVAKGEIIRPIQRIYPLELSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NA59</accession>
    <name>A0AAV4NA59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_730111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020589">
        <property type="protein sequence ID" value="GIX80369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NA59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12833" checksum="F0BD68AD5697E76D" modified="2024-11-27" version="1">MLVGGKHSSLPILKKTETGPLLLTSPERFVYFLGEEKRNWEGLGVAANKRTKSVIGHVIDCYADSGVRLRVLNIKKFERKVFVGMENNKARFGWDGDGDGRFWKINPGFFSVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NB55</accession>
    <name>A0AAV4NB55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_85359_1</name>
        <name evidence="2" type="ORF">CEXT_564051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020652">
        <property type="protein sequence ID" value="GIX81093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NB55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521:SF0">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="303" mass="33945" checksum="66B9BB444A012A4D" modified="2024-11-27" version="1">MASINDTTLEFFTKATPAQWSYVFNKYKDALKAKAAKRTKKGGPEELIRLDAWYQEELPKLIHSRKERYITHEELVQLTKWKLMREKFRPNLIDLVRINTEKAVLTHSKKAFKRLPNLGGAIAMLTCLKGVGPASASAILAAAYPEQAPFMADECMLSTPGVETMDYTVAEYLNYAMELKKKSDHLNTLDSSQVWNPHQIELALWAHFVAGSLDQSILSDLPSSEDLSQNNDNDESEQDQIVDKEKAKSSLQDEDSFDTLDSFASSSGEVSNDAPEYAYAHTDKNKSSKGNGLEPQLKSVAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDA7</accession>
    <name>A0AAV4NDA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_370061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003270">
        <property type="protein sequence ID" value="GIX82807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9429" checksum="1BADAC7519231BA4" modified="2024-11-27" version="1">MYPAIPVPLSSKPDTEWVGQSVTSSRFRTEKQPFTVKDPRRSKETPQFSPKVTMKQKGAQECYPPEHTLLFKYIERFDYGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NH69</accession>
    <name>A0AAV4NH69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_60481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020933">
        <property type="protein sequence ID" value="GIX84137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NH69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11362" checksum="772C2F807F499D0E" modified="2024-11-27" version="1">MESNAINFFKTQGPRVPQTLCVFREYKPIEGKPGSISFTPSKPDLDATEAERRQPTVPAGQSGEAVVSGPEGEVREGGEDHDEHARGEASRGHDDEGAGGRTGDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZG2</accession>
    <name>A0AAV4NZG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TTC8</name>
        <name evidence="3" type="ORF">CEXT_783581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021374">
        <property type="protein sequence ID" value="GIX88931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21341">
        <property type="entry name" value="TTC8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028796">
        <property type="entry name" value="BBS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44177">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44177:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX88931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="382" mass="43514" checksum="CF186813D7EA7105" modified="2024-11-27" version="1">MNSVLEIKAVKFLTDIILKNVLIFTTILEEKPYDEAAWTLKMKALTQEVYVDDLETDEEGIADIIMDENSIAQMARPGTSLKNPNSAKGTSQAYRPVTQSGRPLSGIVRPGTQSGRPGTMEQAIRTRTAFTARPITSSSGRFVRLGTASMLSQPDGPFINFARLNISKKYAALPNVAKHLFEYAYYHDNDIRQALDIAAQATQACHFEDWWWKFQLGKCYYRFGMFRDAEKQFKSSIKQQDMIDTYLWLGKVYIGLDQPLAALDVYKQGLEKFPQETFLMGLNDLDLAVKYYKDVLNYEAIDVEAIACIAAHHFYNDQPEVALRYYRRDYYKWVFVTPQMKLKPGLIEGTKGNLDQAKAFFVAASNLAPHLFEAHFNQRPPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5Z2</accession>
    <name>A0AAV4P5Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021694">
        <property type="protein sequence ID" value="GIX92461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10672" checksum="B8206CBB870845B6" modified="2024-11-27" version="1">MVLPYLKALQISLTSLMTFLLNRIADWTRLTINLLKLTNFLELKNPKDTHVVEDHVVCPQFKDKVFNLSSYYYSARESVVMIGLQATNQRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8C4</accession>
    <name>A0AAV4P8C4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_23571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021719">
        <property type="protein sequence ID" value="GIX92835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8C4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15675" checksum="F702CF9A9D51626A" modified="2024-11-27" version="1">MEVMSHLPLEVIPLFASGSYPSFISGISPGFGSRSFPAFISLNYPALPFEDSLHLPLKVIPPLPLKVLLHLHLEVLLHLPLEVFLHLPLGMYTETYSIEVLSAVREGDRRLDQKEGEGVVASVFLSGTVEFIVWFFTLDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAK8</accession>
    <name>A0AAV4PAK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_728231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004151">
        <property type="protein sequence ID" value="GIX92726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11685" checksum="72DC15806C18BDB7" modified="2024-11-27" version="1">MYPKRACSSLSLTSLIKSSQTALFFINLTLKHCRRYDAVAFPVVTHPKDSSRSDFSEVHPQPLPSLPFPSIPSFSNGYFRSHKQELLGSPVKNRKLNDSRETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDK0</accession>
    <name>A0AAV4PDK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_493651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004473">
        <property type="protein sequence ID" value="GIX95113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15125" checksum="9A478C08DCEFF541" modified="2024-11-27" version="1">MSGSYLISYPSNFLTVEEEHWRHRGLTPTSNIKTEEKLNNLMFTQSTCVQQHSSPSEPVSKTAPQTGWPFECPTEPNAPIVGGPHRIPARDTKQTTITQPSKAEATSPKIPHSPKRGPLKAKHFATPHFEQRQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PMV7</accession>
    <name>A0AAV4PMV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">farsa</name>
        <name evidence="13" type="ORF">CEXT_408511</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01004659">
        <property type="protein sequence ID" value="GIX96537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PMV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000036">
        <property type="entry name" value="phenylalanine--tRNA ligase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040586">
        <property type="entry name" value="PheRS_DBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040725">
        <property type="entry name" value="PheRS_DBD3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003210">
        <property type="entry name" value="PRK04172.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18554">
        <property type="entry name" value="PheRS_DBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18553">
        <property type="entry name" value="PheRS_DBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="156"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX96537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="424" mass="49026" checksum="03C54BC9E04009D2" modified="2024-11-27" version="1">MEVMRHLYFMLFLEGIAQQQLMKAVPQANVGFSKAMSAGWIYIEKKNGMTLAFRKVDNIIDEVQNNLLKLQKSRENEVSQQIKLELKKRKLLQEVKIKSYKIGKGPDFTTSHIKQETDLTPEMIFSSSWKEKTFKPYNFNALGIAPDCGHRHPLMKVKNEFREIFLAMGFSEMATNNYVESSFWNFDALFQPQQHPARDQHDTFFVSDPQSALDFPMDYLERVKQVHSVGGYGSQGYQCDWKLDEAKKNLLRTHTTAVSARMLYALAQQEKFTPTKYFSIDKVFRNETLDATHLAEFHQIEGVIADYGLTLGDLIGTLHQFFNKLGITKLRFKPAYNPYTEPSMEIFSYHEGLKKWVEIGNSGMFRPEMLLPMGLPDNVSVIAWGLSLERPTMIKYKIDNIRELVGHKVNLNMVYSNPICRIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PP53</accession>
    <name>A0AAV4PP53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger CCCH domain-containing protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Zc3h13_2</name>
        <name evidence="4" type="ORF">CEXT_771021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004964">
        <property type="protein sequence ID" value="GIX98788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036396">
        <property type="term" value="C:RNA N6-methyladenosine methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040427">
        <property type="entry name" value="Flacc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38563">
        <property type="entry name" value="FL(2)D-ASSOCIATED COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38563:SF1">
        <property type="entry name" value="FL(2)D-ASSOCIATED COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="572"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="666"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="744"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="793"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="841"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="863"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="896"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="941"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1026"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1047"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1058"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1114"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX98788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1426" mass="162907" checksum="05835434FE91DAA1" modified="2024-11-27" version="1" fragment="single">YFVKMSTKVKRKVTVENSKDDSDQPRRPSVFERLGPGTLNLPPQPTDRHSRTEHNEKCRNWLRTGNCAYGNTCRYKHDTFLGSSRRSSKPEKDVESKDLRHKVKPKRDELKESRTGSASPKRKSSNRSISRSRKGEHESKIKSTVVVTRPRSPSAANPEPSEPKKKSEGNWEDDSDDWPMDAAQLDYKEELTLERKRQQLQRELELELQKERLMSEGVTITKTVSFSESSTTTSTSDSGSISSSSETSSSSSDEDSNDSSSSSSSSSSDSSQRPVKKKGKKSFSKQPTKSMKSKQRDNYDKIKTSRAAKAKKNRSPSPAIESRKGSRKGRDKHNLSPSSPRKRHTDARSDSLNVRMRGPRTPSPTPKASRKQRQWAESSSADSRSADVQRGKNKRHKKKKDSLKGEKRKSDRAFSPPSLNSPNRSSMLPTVSSKKGKLKEEASGKSRHRHREPSPVLLARSSNSTSQSMKLMGTSRYLTEEKPVEKIRGDERSKYYSRKDDEDLLPPNKRNDSRERGNKRTRVSPRKGSRKGSLSPHKERYDPDMLSVASRKMYPHEKEKVDRRRTSISPVRSDRRKLNPEIEKKRDLRDISPREHDSRRDMYRGNEVHGYDKRGGEPKKRFVSPDMKKNREDKGRDHIKDRNAEYESSSWQGDHRKPSSASTGRRTPEPRGRQEIRSQPPLSRNDRPREGELDRKKSGKRDLSVRSVEDTDRARLPSPRRSQSPVHGHHGVREIESLTGNRGRLYDSDIPPGERDYGYGYDSLHDPYLNDRLLPPPDYEPDVLRSYPPDVYPESRYRRGGKEPLDRYEPRDVISPRDVLPHRDIISLTGRGDDYLSDLPMDERPYDDRWQRGRGRDDWDPYPSLPPAPLPPHVAAALDEDRYGMPRRRRASPDWPRNRMDDRDPGLNPGHRPGGRNQMPPEGRARSPKGPGPNRAPWIDRGGRHDSRTGDRKQYDDSQKDRNLDDRKGRDLRKDRGKPTKEESLCDNKPFSAKDKIPIKRQRSPSTSPTIKAKKRCPDLQASELLRYHGGDPLAKKGKEDNKSDSKQTASNRVLKSGKQDSSPKIDNSAERSDVSSKSATENKTKDERKPRKNDESTHGEDEFSDWSDDDDELLTREDFGESEGTTEKHKPDDNVEEGSRRRDRYPTREFQQDYRRDKDVGSRTSSRDRSADDFLHSKDTKSTDGKDTDTHESLSMREDTATDVDEYVTAESVDYDPISDDELDALIEEPDDTLLKPAVEEKSKIVNALDVDWSTLMSETKTEFVPGFARKRFKAAHVLSRIGFSQALAGPELSAKIINICQKQLDEENDTNGDANEAAPQEEKKKEKKFVMEHPVAAFHVAISQNKLERANLFNKVGPYRRALCARRDLQIRKVLCRPLNKLDAPAVTYTPQYTVVDKELYKQSLELLKPKKPVDIQPQTVDVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWV5</accession>
    <name>A0AAV4PWV5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005284">
        <property type="protein sequence ID" value="GIY01225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9336" checksum="87AB586FB76C768A" modified="2024-11-27" version="1">MVVCAAIYRYKLTHTFSRLDKFREQRIGTTNHQGMGNFFSHSVNTYATDIFSTLTPYLGNTAEANNRKVVRALGGLAYKSVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZ86</accession>
    <name>A0AAV4PZ86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_135781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005447">
        <property type="protein sequence ID" value="GIY02460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZ86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12556" checksum="C2EDA866C32D7B4B" modified="2024-11-27" version="1">MMKVGGGGCTVGRSVDSEIASRVVFVSISGQCLSILITHESKYIRGEKKYHLIMERLRGLQAPLLPKKIIRNKIVVWKKKKMKKVGGGGAPWGEVWTQKLAVGWSFVSISGQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q149</accession>
    <name>A0AAV4Q149_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_365381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005377">
        <property type="protein sequence ID" value="GIY01856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q149"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="21772" checksum="9122C1BB8C8C86B8" modified="2024-11-27" version="1">MPKLLSDNHAIVINPHKKPAGEHIRRFNAPVVDDVAGIIPGLETRHVTDEDNDTDVDNVVKFKLIMKEELPTDIGLLHTKSNLERMSSMLDSHLPCSQAHAAPICLICRLAPYSHSGAISGPGSCAGAAPERPPPRLKNGRPVLRRPHSSLIRLLRLSQPSRPTQQCSDPTFSSSWWSPGCVEKPPLPTSRPGRMEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4A5</accession>
    <name>A0AAV4Q4A5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_121231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005559">
        <property type="protein sequence ID" value="GIY03264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4A5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9534" checksum="1AFA05705917F956" modified="2024-11-27" version="1">MESGFSKRTPGESSRPGSAVINYSYLSGSKEVLSLCPSFGECPNCPPVLSYQKKKKKTGGKRITKREFVVHFKQSCISQSTVGDDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q510</accession>
    <name>A0AAV4Q510_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_61331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005667">
        <property type="protein sequence ID" value="GIY04105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q510"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10898" checksum="B39E3A45BB092A38" modified="2024-11-27" version="1">MRGNDSVHREFSCALVAFFSDDNESTLLVRSLSGSIRGGMNAMSSENISKFSKQMRFKVPTLIGSDGRRVTKSEIRQLIKSLQLASAEIHTYEGIQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QB04</accession>
    <name>A0AAV4QB04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_211531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005944">
        <property type="protein sequence ID" value="GIY06295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QB04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16076" checksum="66DB2F28A9089FFF" modified="2024-11-27" version="1">MTSAFMFAGCTNVYPLKILIDSSRFYQACPLLRTDLLLSASSPLKPTLKSGWIRPVSQYQKGPHLLSCSSAARAMGASPGNDPLPSDDEQSVRTMPDGRMRTHSLSRSGDSGETVECRLKRTPTPLGSHAGRALGFWVFLERILYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBA4</accession>
    <name>A0AAV4QBA4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flotillin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_140731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005863">
        <property type="protein sequence ID" value="GIY05631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016600">
        <property type="term" value="C:flotillin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002020">
        <property type="term" value="F:protease binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901890">
        <property type="term" value="P:positive regulation of cell junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000049">
        <property type="term" value="P:positive regulation of cell-cell adhesion mediated by cadherin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045807">
        <property type="term" value="P:positive regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070528">
        <property type="term" value="P:protein kinase C signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002090">
        <property type="term" value="P:regulation of receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF46">
        <property type="entry name" value="FLOTILLIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY05631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23659" checksum="92C9998290D8E8B2" modified="2024-11-27" version="1">MARTAQVKRDARIGEAEARRDSQIKEALAEEERMAARYVNDIEIAKAQRDFELKKAAYDMEVNTKKAESDMAFNLQAAKTRQKIKEEQMQVKVIERAQEIQVQEQEILRKERELEATIRRPAEAEKYRLEKLAEANRNRVIMEAEAEAEAIRLRGEAEAFAVEAKAKAEAEQMAKKADAFKEYREAAMVDMVLDTLPKIAAEVAAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFV1</accession>
    <name>A0AAV4QFV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_313221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006226">
        <property type="protein sequence ID" value="GIY08280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13147" checksum="0D224570D83E1FF0" modified="2024-11-27" version="1">MLMPTERQMIWGRDLFGPICKGPKHPLNTKKNGTGYSVLQKSKCWKNYKWNLDRMEITIFACFEISEDSHSPIQHGYSKICSYCSTSQKRSCRKGTKLNECLVLLLIVPFAIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFX6</accession>
    <name>A0AAV4QFX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2_35</name>
        <name evidence="2" type="ORF">CEXT_761331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006031">
        <property type="protein sequence ID" value="GIY07001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13819" checksum="4216AD92426903A2" modified="2024-11-27" version="1">MIKTYYATSTAIKLSWELSALPSAPISGKYALQYFCLMKHNDISYILHHRLEDHHWQETHLNGDQNVYTLRDLQCGSTYYIYLVAFNSVSQGNSSEVISAKTNGNGTLLILLIRKLCVWAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGT2</accession>
    <name>A0AAV4QGT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_173891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006191">
        <property type="protein sequence ID" value="GIY08039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9947" checksum="9FF0687BB3D8F928" modified="2024-11-27" version="1">MDGRKDVWMEERMDGRKDGWMERRKEGWKAGRKDGWMDGRKEWKVGGWMDGKIREGWMDGRKKLWKEGYGWMEGRMEGWME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJP0</accession>
    <name>A0AAV4QJP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_694651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006245">
        <property type="protein sequence ID" value="GIY08427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12630" checksum="16439EBF48DA8C20" modified="2024-11-27" version="1">MIDLNIKNESSQVRENHYKSEGKECSSFEPTEKRKSESSQSDATSGKGVLAQYVTIPLWCTLSTGGPLSGHSHTHCRHGQLGTIEERGLTFLRDCTNGYIVQPETRCGTVWSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNA0</accession>
    <name>A0AAV4QNA0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase M12B propeptide domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_17651_1</name>
        <name evidence="7" type="ORF">CEXT_349781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006435">
        <property type="protein sequence ID" value="GIY09846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002870">
        <property type="entry name" value="Peptidase_M12B_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01562">
        <property type="entry name" value="Pep_M12B_propep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B propeptide" evidence="6">
        <location>
            <begin position="21"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY09846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19866" checksum="B252841285646AAF" modified="2024-11-27" version="1">MLLQNPHNQELVTHLGTRYEIVNPIQIRQEWGRRLSTRSDRVNGTITHLLQTSLFIETYQYKLHLDLELNINLFPSTLVQFIYEKGGPPLALQELPENCYYHATIRNYPEASAAFSTCDGISNNLFLRIISWMYNCLILEFKFENHSVCISGNHTDREPSAFAASFARKPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3E1</accession>
    <name>A0AAV4R3E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sodium-dependent glucose transporter 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Mfsd4b1_1</name>
        <name evidence="5" type="ORF">CEXT_809411</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007171">
        <property type="protein sequence ID" value="GIY14927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23121">
        <property type="entry name" value="SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23121:SF9">
        <property type="entry name" value="SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY14927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="19504" checksum="82E5DA072A940A50" modified="2024-11-27" version="1">MLTTYVVKGPLKLTSTIGSYMTSVFWGSFAAARFASIFLAIWFSNLQMIIFDIIICITGALILVIFGASDIWAVWLATVLLGVGTASFFPAAVGWTDRYITMTNKIASSFSIGASFGEMVIPYIIGIYINTVPKVLTYMVAASSILSVVVVFILWLILRKQQDKYLKEEGTTNVVVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R473</accession>
    <name>A0AAV4R473_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_223117_1</name>
        <name evidence="1" type="ORF">CEXT_619852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007354">
        <property type="protein sequence ID" value="GIY16252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R473"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="261" mass="30208" checksum="0C2199A0E27961CA" modified="2024-11-27" version="1">MPTIYTAGEKDTLVAMVRRSPGVIQLRLCFFNVLPSFWLHLDGDEYDSIQLQSLSEVAEIYYQLLKKAMESSAEETKSKSSFDGSLQEQTANELTQFAERNQIIFFSQTLAELITLLEWQNEKKKPEVQESAIYNSLLRVEKAANNTSTWELCGQDLDGPLISISNFEMNMLEQTVSMYLVDILDKDRSQTLFFPLDEVFESDILVKWRILEKIASIKITPHQTIYKHKLTECIRERIQTEVSDWLDKEFSKLKITGKPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5Q2</accession>
    <name>A0AAV4R5Q2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_349451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007489">
        <property type="protein sequence ID" value="GIY17263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5Q2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17778" checksum="592F7520B2F23D71" modified="2024-11-27" version="1">MKHDTFQLHTKNNFCLLLHIICILQNNVQYIKRYSNSSTFKTTAAENISKTFLKPPPPQPPSHLGGSTFLPFLLDDFERNGREVFTRKVNDENRNNNKNKISKRRKGDERGWCKAKRFSSKEVQSGLEISTSENDTDASSAGKSARVTRHWWIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5W8</accession>
    <name>A0AAV4R5W8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_602881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007251">
        <property type="protein sequence ID" value="GIY15597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5W8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="14967" checksum="4EFE5EFE7E3B1058" modified="2024-11-27" version="1">MEDQGEGNSPSCFASVFSEEELFQNCTIICPRPEAGQGVFKGNSPCFASVFSEEELHSSNAPSSGGRASPAQDHKLFGLLWSGSFQGVTRLVSLPFSQKKSCIREMHSSSGGRAVLQNGIRMNKKNRYLYFEMIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8H9</accession>
    <name>A0AAV4R8H9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_139691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007590">
        <property type="protein sequence ID" value="GIY18253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8H9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10754" checksum="F5F1DC4EBD7F1547" modified="2024-11-27" version="1">MAIASRLKDSHHPAFMNECNIEDRISLQNFGSGLFLFFSFVETVYLFSVCGQFCSGHLVEFPGHYPPSPHFELFCIVFGKSRHAQRKACETASSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCG5</accession>
    <name>A0AAV4RCG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_153211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007544">
        <property type="protein sequence ID" value="GIY17778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11643" checksum="3F9F10C685CD972E" modified="2024-11-27" version="1">MLCYCGIQFWKWSKDLVSYREEDSEGDGCLGSFGGWRGCINTILNVRPDGRVVLFLVHARERGVCYCGSQFWKWSKDLLSYREEDREGDGRLEFFGGWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPR1</accession>
    <name>A0AAV4RPR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_515801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008130">
        <property type="protein sequence ID" value="GIY22295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14973" checksum="0870CBF5661D0968" modified="2024-11-27" version="1">MQEGFSRNFRRKLPVDNIRLGRKKPTSEWEFENDFKSALKAVFRKRSSIGGYYSGNRYATWHSISHIFVRGISDSSNENIRPVNHFERGGKDSVGDLSYVSCHFDLMQLPLYLQLHTEFKDCFFLEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTQ8</accession>
    <name>A0AAV4RTQ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Jafrac1</name>
        <name evidence="12" type="ORF">CEXT_451361</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01008367">
        <property type="protein sequence ID" value="GIY24201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF163">
        <property type="entry name" value="AT16346P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY24201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="21789" checksum="A4D399F23CBC298F" modified="2024-11-27" version="1">MAPELTKPAPYFEGTAVVNGAFKTIKLSDYKNKYVVLFFYPLDFTFVCPTEIIAFSDRVDEFKRINCELVACSTDSHFSHLAWVNTPRKDGGLGKMNIPMLADKSGKISKDYGVYEEKAGIAFRGLFIIDENGRLRQITINDLPVGRSVDETLRLVQALQFTDKNGEVCPAGWKPGDKTMKPDVQGSKEYFKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWQ5</accession>
    <name>A0AAV4RWQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_342351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008729">
        <property type="protein sequence ID" value="GIY26768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="8246" checksum="21DEEB0449A758CF" modified="2024-11-27" version="1">MLRFVMLVTRWRYIEVKVEVELHRFPNRQEWKSEDPGSNIVEVQVKFPGKNEPQRFRLDSAKEVSKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9D5</accession>
    <name>A0AAV4S9D5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_373381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009016">
        <property type="protein sequence ID" value="GIY29030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9D5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11180" checksum="0231634C91140293" modified="2024-11-27" version="1">MWCGMPFLKSRVNFPNKKYLENFILSDPPQQTTEFHFLSANIPLVTNVFKCHPPKRQRQNSLESIFDVDKTVPNLPSVAELKPYAFYVVDESKFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAH4</accession>
    <name>A0AAV4SAH4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial enolase superfamily member 1</fullName>
            <ecNumber evidence="3">4.2.1.68</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">L-fuconate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ENOSF1</name>
        <name evidence="11" type="ORF">CEXT_259861</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O</text>
            <dbReference type="Rhea" id="RHEA:22772"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:21291"/>
            <dbReference type="ChEBI" id="CHEBI:37448"/>
            <dbReference type="EC" id="4.2.1.68"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.68" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01009239">
        <property type="protein sequence ID" value="GIY30502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050023">
        <property type="term" value="F:L-fuconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000007">
        <property type="entry name" value="Mitochondrial enolase superfamily member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="10">
        <location>
            <begin position="35"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00061144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00073815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00078003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY30502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="31819" checksum="8BCE171CCE8378FE" modified="2024-11-27" version="1" fragment="single">LLKKKEDGKKEREAKLLRDGYPAYCTSVGWIGYSDEKIKKLCKQKLQEGFTAFKAKVGQNLEDDKRRLSIIRKEIGEENLFMVDANQKWDVQEAISWMKELTGFNLLWIEEPTSPDDILGHAVISKALKPYGIGVATGEQCQNRVIFKQLLQAGALQFCQIDSCRLGGVNEILSVYLMAAKLGVPVCPHAGGVGLCELVQHLSAWDYISVSGSLDKRMIEYVEHLHEHFEDPVSIRRGHYETPLRPGYSTKMKDRSVSDYQYPSGDVWKNMFAEGKFSKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIV5</accession>
    <name>A0AAV4SIV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_523161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009516">
        <property type="protein sequence ID" value="GIY32472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15342" checksum="713DBC515DF63222" modified="2024-11-27" version="1">MQNNLINQTGNLPPTSACKLQWWRGTEHEFVKETVDCPREQPCPLAVPLVHIESFLLPACSREEKHPQRISTSSRIVVHFARGYGCYFAEWKIGKEEKEKKAVLEQIRVEVHVPLLSSSCRPHIPSFPVQRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SS48</accession>
    <name>A0AAV4SS48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_383031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009999">
        <property type="protein sequence ID" value="GIY36021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SS48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="18724" checksum="CF90C307374E0A1A" modified="2024-11-27" version="1">MLSRYRPRGFREIEITAPGRCWCGQRRIWTLPNIVIEWTWRSDLFSSWLVVNILTIWRLRGMHIRNNLNWQVTPQNWQSRQPFVQLRAELTVILRGNNHEIRGVPGFREIEITAPGRCRCGQWRIRTLPNIVIEWPCRTALFSRKGENYSPESSKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SW51</accession>
    <name>A0AAV4SW51_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cationic amino acid transporter C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_186261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010078">
        <property type="protein sequence ID" value="GIY36710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SW51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029485">
        <property type="entry name" value="CAT_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13906">
        <property type="entry name" value="AA_permease_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Cationic amino acid transporter C-terminal" evidence="2">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY36710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="229" mass="26083" checksum="D06DA49ED3F26A2A" modified="2024-11-27" version="1">MCINFQDHGSADAHPSLPLDQPRRSFGSYGYLCDEDGGGALLADHHHGPHRGVRHARARKQERGSHLLPARLPVRHYLLFDHYLATAADQMRLEIQSSCVPFIPGIAITVNIYLIFKLSVLTLVRFLIWMSFMFLLRPFHVFLVRHQEQLSELQTDKPLELKIPQDRVQNNLCPPDNNQYMMAGGGNEVIEESYVEPAYNGYVAQPDPLSVDPWSQPDPLAEDPWAKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZC3</accession>
    <name>A0AAV4SZC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Basement membrane proteoglycan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">unc-52</name>
        <name evidence="16" type="ORF">CEXT_85872</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010424">
        <property type="protein sequence ID" value="GIY39199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042562">
        <property type="term" value="F:hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000119">
        <property type="entry name" value="Suppressor of tumorigenicity 14 protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000062">
        <property type="entry name" value="Terribly reduced optic lobes, isoform AI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000034">
        <property type="entry name" value="Laminin_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056863">
        <property type="entry name" value="LMN_ATRN_NET-like_EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF15">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24973">
        <property type="entry name" value="EGF_LMN_ATRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00052">
        <property type="entry name" value="Laminin_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00281">
        <property type="entry name" value="LamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51115">
        <property type="entry name" value="LAMININ_IVA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="22"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="14">
        <location>
            <begin position="800"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="14">
        <location>
            <begin position="1054"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin IV type A" evidence="15">
        <location>
            <begin position="1193"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="13">
        <location>
            <begin position="1430"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
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    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="412"/>
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        <location>
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    <feature type="disulfide bond" evidence="11">
        <location>
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    <feature type="disulfide bond" evidence="11">
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    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="485"/>
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    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="497"/>
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    <feature type="disulfide bond" evidence="11">
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    <feature type="disulfide bond" evidence="11">
        <location>
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    <feature type="disulfide bond" evidence="11">
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    <feature type="disulfide bond" evidence="11">
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    <feature type="disulfide bond" evidence="11">
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    <feature type="disulfide bond" evidence="11">
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        <location>
            <begin position="1449"/>
            <end position="1458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50027"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY39199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1483" mass="164373" checksum="252524D44ABB999A" modified="2024-11-27" version="1">MNLSAALRASSFSRDVTWLLIAPNSEDGFAVEIECAPDEFHCKDKTGIESYQHSDGKPDCPDNSDEQNCTGVVCPPGTFRCDNGSCIDLYLRCNGRSDCPDRSGADEKDVVTCTSSQWQCDFGQCLERNKLCDGIVDCPDDNSDERDCGVPGCSADKFRCSDGTCIPADNKCNGRRECRDGSDERNCPCPSDKFMCANKFCIDLRRRCDGYSDCQDSSDEKDCPGECEAGQFRCADGKACIPSSSHCDRKYDCQDGSDELDCRRPTTQCRFDQYRCSDGMCLNIAQRCDGNIDCSGGEDEAGCGTCPENQFRCSDGSCINIKMRCNGAFDCRDGSDENNCEIKPLCRITDFTCRDGTCVNQTIKCDGVVHCQDGDDESICKSRQRCDGRSHCPNGEDEADCPVECQPDQFRCKNGQCIGERRKCDGRSDCADSSDELDCGICKPGDVICRDGSCVDISKRCDGRRDCSEGIDEENCECPATEFRCGDGTCISERRRCDGYPDCRDRTDEANCEKCAENMFKCGDGTCIDLRRRCDDRRDCFDNSDEENCEPKTCSPDQFRCNNGECIANSLKCDRKYDCRDGSDEISCGAFFLSAPEVAVPCYFMFYKKNYAVTCSSNQFRCNSGECIDNSLKCDRKYDCRDGSDEFNCVAEVCAANQFRCTNGQCIDSSLKCDRKYDCSDGSDETSCARCQPSEFQCGDGSCVESQVRCDGRNDCPDRSDEKDCGCTPTQFQCNNGECVDSRSRCDGIPDCNDGSDERDCRACQAGGYVCANGQCIERYQRCDGTFDCSDYSDESDCAPEGGINIKVYPERQSIRQGREVVFRCRDEGTRRSPVKWIRADNLAMPPGHTDRGGRLTIPNIQPEHSGVYICTSAGATRGSSSSAQKTAFLSVQPSVPFYGTSFPHVESSNVGGMTQFLEMYLLHLVNTATRSLFQDREATCQNGECIPRAYACDGDFDCTDRSDEQNCDYQYQCQPNEFQCDNKKCVLKVWRCDGDNDCGDNSDEKSCSPNPAGSPCRYDEYRCLSGDQCIPKSFQCDGEFDCQDKSDEIGSSPTITQPPPETLTVEEGETVTIVCTAVGNPTPIISWRLNWGNIPGGPRVSVSSENGRGTVTIREARQTDQGAWSCEAINSKDSVLAIPDTVLVVKPKAGVCRPPLFNEKASVSSDCLRCFCFSVTETCYSSSLHVIKIPLQTEIAIVALQKDGRGNYEDAGPRYPPNQNAIQYNSANREYKVESSVRNDSPRDVYHYWSLPPEFLGNQLNSYGGYIRYMFRYSAPFPRSTPNIADIIIKGNDLTLYHVVKQPFGPQRDNNIEVRFWEGEWHKNEAQGRGDVPFGDVTTRQDIMMVLQNIEAFYIRATYDDEMIHSSILNFQMDSASLSDPSAPQAVFVEKCSCPQGYTGNSCEECSEGYSRRKTGSGLGDCVPSRVPCNCHGHSSLCDPVSGECLNCRHNSEGRQCERCKRGYFGDARRGTQMIVNLALVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0X3</accession>
    <name>A0AAV4T0X3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_192681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010181">
        <property type="protein sequence ID" value="GIY37533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0X3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9422" checksum="A50CE946FFCB484D" modified="2024-11-27" version="1">MAGCGWEGGVEKGLGRPHVAKLHHGKAHGWCVAGAEEGQSKIDIKPFFSTPHPVLDQSAPDALVCLELREWNGLLLFVHLLFPWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4I3</accession>
    <name>A0AAV4T4I3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_704391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010485">
        <property type="protein sequence ID" value="GIY39582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4I3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12817" checksum="8EEB65651903CC65" modified="2024-11-27" version="1">MKDDQHYGRPVTLRTDENFGKSSMEWLEILKLLHKLRLYNPSNNGGKNPFPHEWTRRVSSLDDCLLRIFHQHDHCRNWQEFQHSIRRDHGGVPGQPSWHLYPLACCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T531</accession>
    <name>A0AAV4T531_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_812491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010743">
        <property type="protein sequence ID" value="GIY41713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T531"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16922" checksum="60AA5CDD14D22DE7" modified="2024-11-27" version="1">MRAWKKGTANKGDLLEYDAPRRSDVAPRNGHPFFHDGLHVLKENERKIKKKKRKERIKEEEKKKKKKKEGDYPHLLIFPGPTHIPPPFLKDERRRNCRPQMLHRDKFVPIKNVSLKNTLLYHQLVKRRKGRENAFKSDREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T780</accession>
    <name>A0AAV4T780_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">X975_05963</name>
        <name evidence="14" type="ORF">CEXT_747461</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fibulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010699">
        <property type="protein sequence ID" value="GIY41156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T780"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000005">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000139">
        <property type="entry name" value="Fibulin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000008">
        <property type="entry name" value="Signal peptide, CUB domain, EGF-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000240">
        <property type="entry name" value="Vitamin K-dependent protein S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050751">
        <property type="entry name" value="ECM_structural_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055088">
        <property type="entry name" value="Fibulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24034">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24034:SF209">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22914">
        <property type="entry name" value="Fibulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043551300" description="EGF-like domain-containing protein" evidence="12">
        <location>
            <begin position="23"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="653"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="850"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="892"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="936"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY41156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1199" mass="132583" checksum="E459AB0709117BED" modified="2024-11-27" version="1">MDKRVFLAALLTLVPALPHARGDLEPVLERCCSSGVAWSRNHTTCTGPGEASKIPPKDRLTCLTALYICCVRAHRDALCESGKDAARTQRQCSLLHDQVLKDCCDGCALGLEAVSLQTPCNLQHFSFGSPWDEAFRDCCQNPTLGTSPQQGGGGCGSGNPCDQKCEEIGQQVRCSCYPGYKLAADLKTCEDIDECLLQAHNCDPLTESCLNSIGGFQCLEKRAVQCPTGYRLNEEKRTCDDVDECLSNVCPQGTTCINNKGSYRCVSSHVDQACRPGLQFHAASGRCIDVDECADGTDSCDRNLKICQNLPETYQCLQKPTRGRNCPAGFKWQDDNCEDVDECAEQLSQCQDPQLQCRNTIGGYSCIHRCPPHRVFDPQQATCVDPQEATDCASGLLKCDADAVCMAVDGKHRCVQKSVNDKCDAGFKPETASDGITRICTDVNECEEFPDSCDMHRERCQNEWGKYDCVPLLQQTTPEPPCPPGFRKDPRTQQCVDVDECLEGRHQCQTDKEQCQNVPGAYRCQQITTAPSTPRSCPLGRRFDSRTQSCEDVNECEEGTHNCDPISQNCLNAVGSYRCVNKVTCPHGYRWLQWKSKCEDENECTEGTHDCDRYTQLCINTAGSYQCQSRPGQVVSNCGTGYVYDTSQDTCTDINECDLLRPCQADQMCENSPGSYRCVCPQGFTLDAFTRECKDVNECQLQLHSCAVSQRCDNTIGSYTCVRTTSCGTGYTLNAALSQCEDDDECLLGTHNCGPGFACRNTLGSFRCDRVKCPAGQKLLSDGSCKVIVCGAGMEHDDDGNCIDINECARIQPCRLNQRCINTMGSYRCQNLLNCEAGFELNEVGDQCVDVDECARRIAECGSGQTCRNKQGGYVCECPRGYSLNPQRVCEDVDECSRFRGQVCASNSECINTQGSYTCNCNDGFRAAGTDKSCLDVDECAESPNICQQTCNNVWGSYQCSCKLGYTLAPDHRSCQDIDECEVYGGIGSLCIGFCVNEPGSFKCSCPSGYRLSSDGRTCQDIDECQEQNVCSDEKTACFNTRGGYKCNRIECPPNYVRDKDHRNRCKRSQRDCSQGGAECLKEPLTYSYNYITFVSNIRLSLSGQLDLFTMRGPRFHTTTVHFTLELREARAPPGTSPTTQDYFRLRRTNYNEAMVSLARTIQGPQEIELDLIMKIYQNGLFAGSAVAKIFIFVTEHEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TG01</accession>
    <name>A0AAV4TG01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_753371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011039">
        <property type="protein sequence ID" value="GIY43817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TG01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15358" checksum="4275E1870E4538A6" modified="2024-11-27" version="1">MRGDGRYCFSPHTIDRIVIKTRHGALTEGIKNAQPPSMSGVRVRVGIMEIDLQMSHIFTCPHIYIFTFHIYLPGWDPLRDRQRVGKLPDFNNGKKVTLPDVASSKGPSAGVTRRTSFKKEEIFTPFKREESSLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGE1</accession>
    <name>A0AAV4TGE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_561481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011267">
        <property type="protein sequence ID" value="GIY45390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14354" checksum="706A421DDA5717A1" modified="2024-11-27" version="1">MRQRILRSPEEKGDCQCQTMEVKSRYSSIGVVIPLGSSLVPTIQAQNNTTEFTELTELAEIYEEGDKEIGSIFDDDFFHVNGNWNGTEEAQNGTQPREREWTGTVIQQVVTLSIIMLLTLIGNTQLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIS1</accession>
    <name>A0AAV4TIS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_366001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011257">
        <property type="protein sequence ID" value="GIY45292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13241" checksum="0874D4463711D35E" modified="2024-11-27" version="1">MVATAHLANGVQLKKMVATTHLAKGVQKKKNCSYYSSREWCTIKKKMVATVHLANGVQNNPGFKEFMTYYSTTDSRGDYYIDLPYFSACNQLIIHRKTLEIHIVNYKSPYNLWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQ71</accession>
    <name>A0AAV4TQ71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_121321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011600">
        <property type="protein sequence ID" value="GIY47606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQ71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13671" checksum="5904A580CEE34CA3" modified="2024-11-27" version="1">MSTCLSVGPRSLHLHCSSALRANVLGDRGLRHEQRSRIQRASQPYTVLLRPSLHDERGDALQVQNRRADRDSNHSLQLLPHRNRGPGDPGWLTPLPVRARGSHGGECSPTNLGRPQMSTTTSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSQ4</accession>
    <name>A0AAV4TSQ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_466791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011761">
        <property type="protein sequence ID" value="GIY48854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14367" checksum="7E93C3D935A58A34" modified="2024-11-27" version="1">MITIINCQPPRNYEALQNALSCESPINERLAEWRLRRSLQLLQMDGDDPGQGWKHSDGYDYHHQLSAPRNYEVAERFKLRITKNIRTIKERLAEWRLRRSLQLLQMDGDDPGPGYEERKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U202</accession>
    <name>A0AAV4U202_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_271391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012158">
        <property type="protein sequence ID" value="GIY51766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U202"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15474" checksum="48E80F2F56ECC175" modified="2024-11-27" version="1">MSDADVFFANKNRITARTSKRDQFSERLAISIVLNLPMGTVTTYPHQLYDKTCPAALRFFRHPVCLIERATSFFHVLSANCFTINFHDLTECQMRTYSLPIKIESRLTSKRDQFSERLAISIVLNRMGTLPTPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4C2</accession>
    <name>A0AAV4U4C2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_813731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012255">
        <property type="protein sequence ID" value="GIY52557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4C2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13970" checksum="FBB94E64D6FB7C4D" modified="2024-11-27" version="1">MVRSELFCLSYPVAGIECTVVLLFHYAAAQKCSFHLTFFFTLIFYSVILIQRTISPLSVLGPEKPMQSSAIVNCPREFPDALFYKALPWFAPSCFVYPIRWLVPAQRRVINRAMRHRFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U700</accession>
    <name>A0AAV4U700_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012374">
        <property type="protein sequence ID" value="GIY53549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U700"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15791" checksum="93577B233F8A0C4B" modified="2024-11-27" version="1">MRLREKEGSLSIEKLSFGRVMNERVLASYCPSSCTWKYQKESIACEEAYDDWIKECIGGHRVSLVNLNNSQNISTNFPFFKINFVFVESPWPSNFTCEKSPQLVRQRVIGAVIRFTGVAIFIGNGVTHEQLSPDCLTCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB21</accession>
    <name>A0AAV4UB21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Toll-like receptor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">TLR2</name>
        <name evidence="15" type="ORF">CEXT_184081</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Toll-like receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012573">
        <property type="protein sequence ID" value="GIY54920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10140:FF:000001">
        <property type="entry name" value="Toll-like receptor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365:SF530">
        <property type="entry name" value="MSTPROX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365">
        <property type="entry name" value="TOLL-LIKE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01537">
        <property type="entry name" value="INTRLKN1R1F"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0391">Immunity</keyword>
    <keyword evidence="3" id="KW-0399">Innate immunity</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="TIR" evidence="14">
        <location>
            <begin position="138"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY54920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="292" mass="34498" checksum="CD176E68D8CE0478" modified="2024-11-27" version="1">MLTEFRQVSKYLDLRRNPFNCSICGMDDFSELLKSSNLTLGLPPPNKMENSLPLCAEPVALRDQSFIEVELGLMACIDKEIEVLSLTSLILLIVAMLFITIMLYLCYFFRWYVRYWIFHVRVKFIEKTTLDIGKVRRYTYDAFVSYNSQDTNWIVRHLIPALEREDPRYKLCLHDRDFEIGRLIIENILEAIEASRNIILVLSESFIKSEWCMFELHMAQHRLFDNTRDCLILIKLKKLDKKLYSRNLMYLEKTRTCLTWTEDKADQKLFWERMRKILGAPSSASISAEVCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UI47</accession>
    <name>A0AAV4UI47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012928">
        <property type="protein sequence ID" value="GIY57592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UI47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11805" checksum="6F8FD08FEA19D811" modified="2024-11-27" version="1">MWLWPFCTSWLKYSYGNDFSVLNASVAESRFTRTFSLLVSTESKSYPHLFYALQNMEGVKGMSSSESHCPPLKFGIVRVYIVDGFGSRAMNLKACMKDSPVLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKD9</accession>
    <name>A0AAV4UKD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_698051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013044">
        <property type="protein sequence ID" value="GIY58253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15468" checksum="C5D2BC3D3BEAF2E3" modified="2024-11-27" version="1">MKDKRCQLMVNLMKDKWCQLMVNPDEGQMVSTNGESDEGQMVSTNDESDEGQMVSTNGESDEGQMVSTNGESDEGQSEIECIPPEISDQKNPLLLRQESLFLLNHLQNLHSLTPQRICNLLTLCNLLKLNHLMIIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPN7</accession>
    <name>A0AAV4UPN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_210401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013232">
        <property type="protein sequence ID" value="GIY59686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="14147" checksum="81E6F7F4F353B340" modified="2024-11-27" version="1">MEQKFFRATEQCEAFRGNRFKIRVISTTRTRVFDKILISFHPLRPRFASVHPTKMLIRIEEQGALTNHRSVRSADFFEVQTMFDTTEAPMSGTILIFKMWLQLREFVKCLFRRIEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPR5</accession>
    <name>A0AAV4UPR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_464091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013234">
        <property type="protein sequence ID" value="GIY59716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9985" checksum="A82E76BE8F591419" modified="2024-11-27" version="1">MVEQIYSAGYSILNQLFQEQSRKTAAPAAYQTSVLGKERVRGHEKVFFRIPLCCEGILGGNACCNRNGSQARLKMDFFDMQYLCILQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4US44</accession>
    <name>A0AAV4US44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_445911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013382">
        <property type="protein sequence ID" value="GIY60832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4US44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY60832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10108" checksum="B86C5766659FEACF" modified="2024-11-27" version="1">MRECPCQLEDIPLHRGLRKMSLAMDKGLIVYLSFGAQSVHLFFLSFIVFLSRLGWLTPRPDGRGPTMDIHTATPHGAYNEGGHRDRSGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1H6</accession>
    <name>A0AAV4V1H6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_579601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013788">
        <property type="protein sequence ID" value="GIY63815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1H6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11531" checksum="142AEF5CB27000DF" modified="2024-11-27" version="1">MELPASVAGSNSTWKGVCKWTTTYYLWTTLLTYTMGHYTMLHYGLVIGEFFFFSIRSGLYNYPCMEQPASVADSNSTWNGVCKWTTTYYLWTTLLDTIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGJ8</accession>
    <name>A0AAV4VGJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_55821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014474">
        <property type="protein sequence ID" value="GIY68984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="35703" checksum="90A8F655ACDBCB26" modified="2024-11-27" version="1">MRLDSRVQIPSTLLKDVIESCTVLKGVEYARLNVRNNFCHRHRYGKSQKITQCGQLVSEVLYAVKYPCSNHGTVLKETEYGKLNGQMLYSQLVSDVQCKVEFMCSNLGVVLTDDTNARVMSVMGTDMGNLRSPPVSKVWRTVRCLRSNPCTVLKDARLKDHHNRWIGIEWGRLDSPLVSEVWREVRCLRLSPSAMLADARLKVQNNVWIVTERGDSIFQYIVFCSLVVIKGLCEIRYLCSNPSAMLADARLKDQNNMWIVIERGDSVAQCPLVSEVWCIVRRLRSYPSTVVKDARLKDQNVVWIGTEWGDTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUA5</accession>
    <name>A0AAV4VUA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_657951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015043">
        <property type="protein sequence ID" value="GIY73189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13855" checksum="A4005B247EF42DBE" modified="2024-11-27" version="1">MSSACRDTRRLSLEVPMCLLLNQIFDLRSKFNLAHSYGAGVIWMPYFLLPSLRSQGERRGFCLLLAWSFVSLRSLRVISRIGFFRKKRRINLFKDGKPFASRLCTDGGLKREIFGFGEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUR3</accession>
    <name>A0AAV4VUR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_103798_1</name>
        <name evidence="2" type="ORF">CEXT_120421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015095">
        <property type="protein sequence ID" value="GIY73531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="24152" checksum="97F249987930C94A" modified="2024-11-27" version="1">MASSLIAQDNDLFRQLLSLHDSIAELRERQRYSACLDDDDDEEEDDIDITECPGHRNRHNSPSLESLSDPGELPETSPESTLSSRSSLSANSSDFKPRKYHNPCSSHRNRYRKEDGKQRHRATNNSKDDSRPLIFIDKSEICFRCRKMAPLIEDQVLLLVCIICMRIWNPMILEFICKDLILILITKSSYAIRARSFEVYSEKNLLCNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VX84</accession>
    <name>A0AAV4VX84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein kinase C-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZMYND8_1</name>
        <name evidence="6" type="ORF">CEXT_807561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015296">
        <property type="protein sequence ID" value="GIY75055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VX84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46453">
        <property type="entry name" value="PROTEIN KINASE C-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46453:SF5">
        <property type="entry name" value="PROTEIN KINASE C-BINDING PROTEIN 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="5">
        <location>
            <begin position="82"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY75055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="22654" checksum="97B2584C428BD9AA" modified="2024-11-27" version="1" fragment="single">MKVHSTTDKPFITVIKPESSRARKCLSFEEVEDNSFEYESPSSNSKANSAETSPYKNFPDVSVCLKEEDHINVQRELGKTNDCYCWVCHRENVTLTCIACPRAFHQKCAGNYVDMNDYKDWVCPECKRILQAENVDTQSTVLSEISLDKLCSLLKFSLNKMKHRAGVAFHQPVSLDHYPMYLHYIINQWIFSLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VXS5</accession>
    <name>A0AAV4VXS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_731151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015245">
        <property type="protein sequence ID" value="GIY74675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VXS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11161" checksum="B7183E15FD472B03" modified="2024-11-27" version="1">MPLPSACGGGQRNSVVVSSKQMYSPPPPPTNDSEQTEPVDFSTGHDDRVPGPHMMPNATPSPPPRSPVTGRSLSTPLLIAQRNTFPIRKVLWDLRQTECSITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WAS9</accession>
    <name>A0AAV4WAS9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_521211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015829">
        <property type="protein sequence ID" value="GIY78989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WAS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7651" checksum="8507D2F70B891EDD" modified="2024-11-27" version="1">MRSNTPRHDFSRGAKMCPFRNEKSSLLENLSFRAPTPPEVLGSEGPSPHAQNIHRRSSVGLSDVRFSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCC3</accession>
    <name>A0AAV4WCC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_642201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016015">
        <property type="protein sequence ID" value="GIY80496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10333" checksum="6B1A2D388EC13582" modified="2024-11-27" version="1">METEDFIPLGRSAIVAAFPFKRGGTFIGPPLLSAWKACTPLRANNSRRKGVENTFTCLLFEFCIPTRTPNTVLYGVVGDTMWGDLDIVQCFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIL4</accession>
    <name>A0AAV4WIL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_124485_1</name>
        <name evidence="1" type="ORF">CEXT_352191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016251">
        <property type="protein sequence ID" value="GIY82497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15193" checksum="B427DB6D02FB6A39" modified="2024-11-27" version="1">MRDRLRSQRSQTLITKKNQGKVMERASRAWQLRHNSIVARIKNAVSPKCDILGENRDISGSGLRPDLFIKHKQDYYLVEVTVPFDNRCAALHIAHQRKVDKYEPVLEVLKSQGINATIIPFVVGALGSWYPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WKU1</accession>
    <name>A0AAV4WKU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_540841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016393">
        <property type="protein sequence ID" value="GIY83511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WKU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9538" checksum="D5F9FB0D86A8630E" modified="2024-11-27" version="1">MSSSLQKKWCIQKLLFQRKESLRDKPIGHVERWVARKRMCLLGPARGKRRLFRLPALILDLTDVSLEHCIFNSLSASAATFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X337</accession>
    <name>A0AAV4X337_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Polr1a</name>
        <name evidence="11" type="ORF">CEXT_663601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01017077">
        <property type="protein sequence ID" value="GIY88580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X337"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02735">
        <property type="entry name" value="RNAP_I_Rpa1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047107">
        <property type="entry name" value="DNA-dir_RNA_pol1_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="8">
        <location>
            <begin position="23"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="10">
        <location>
            <begin position="157"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="9">
        <location>
            <begin position="252"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="633"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="656"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="681"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY88580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="944" mass="106417" checksum="3E9F6F9FE6EBE6EB" modified="2024-11-27" version="1">MQNWKTHPAREWLAGGSPLKGESMSESEVIVREGELLCGVIDKAQVGPTPYSLIHMCYELYGGEVSNTILTALARLFTHYLQYESGFSLGTEDIVVTKKLIKKRRRILRKAKEEGLIATAHALDVDNPDNPEMGELLHKYNEAHFSRDDFILKVLDMEMKKVTHSLNNKINEVCTSNGLMKKFPYNSLQLMVESGAKGSSVNAMQISCLLGQIELEGRRMPLMVNGSTLPSFEPYDTSPQAGGFVAGRFLTGINPKEYFFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLTVVADQTVRDSDGTVIQIVGSFIIFLLSVDKDLVIIFSLNKKWQKKHWDPTIHRSSLVSSVDFKADDLGDRNQKIFSMLNELDEMEKKVFNKTKEKCPDPVNSKYRPDVTFGSVTEKLDRLISDYVSKNPHNLLWNENLSRKKNGNLSVENFKDLCYFHSMKSLAEPGDSVGLLAAQSIGEPSTQMTLNTFHFAGKGEMNVTLGIPRIREILMTASKSIATPTMDLPFLDQPKIKQKAEQLKLILSPVFLKDVIHVIKVKEYLSVVVNQLPTRNYVIRMQFLKHSEYKEHINTSPSKILYYIEKIFIKKLIDALKKKIRKSSSSKLSISVTKDEESVSFKYEPAEVDEDAPPTVSEVKKVDDADSTDESENEGDTTSAESKKRHNQEQEYEDPEEEDLVAESDNESDNDNDEEITVKQEVMSEDEKEPTMRINYVASSHTHWVTGYDFDIAHERWCEICLQLPLNENTIDFKSFIEEELIKAKIHSVPHINEAVLVKNPDDKEGCNLMLKTNGVNFLEIFKYVDLLDINKVYSNNIHTIANIYGIEAAVQAIKRETVKVFAAYGIQVDPRHLSLVADYMTCSGYYRPCNRTGMNGNASPLQQMTFETSKNFMTDSMVMGVKDNLASPSANIVVGQIPKTGTGIFDLLSVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4P8</accession>
    <name>A0AAV4X4P8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_686991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017099">
        <property type="protein sequence ID" value="GIY88754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4P8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8713" checksum="07CA94092DAFD721" modified="2024-11-27" version="1">MHSFLNEFREQTWMDRCPKMDWSRLSPDEHLEDSLPRVQEALRLKERVIIKYLCVAFRQSSMGLFKPFRPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5L1</accession>
    <name>A0AAV4X5L1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_112511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017150">
        <property type="protein sequence ID" value="GIY89074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5L1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15332" checksum="4FAA5DE4E4073096" modified="2024-11-27" version="1">MPFYATLNLNRITKTTVKDALSRFDTPVHHRACQYPIRLRRFSPDRLQVPVFISHEYRIEIISPPFRHPSCALIESCGGGYLESGRSDVRISIWMRFCAWLAMETNLFLAKHCVKGALEYFLVYYMGPDGSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5Z4</accession>
    <name>A0AAV4X5Z4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_503771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017340">
        <property type="protein sequence ID" value="GIY90696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5Z4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY90696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11415" checksum="0F1AA912B862CC60" modified="2024-11-27" version="1">MPLALSKVGIPSSLNLSSFSPKLNASSRGIQTASGSQMMKLLPQAPIHAYAVISTIFIVSLYVYGPQEWKHTHCSPPRAQLQIRHHHHFTALSSISSSSSSFLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9Q2</accession>
    <name>A0AAV4X9Q2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_364771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017405">
        <property type="protein sequence ID" value="GIY91352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9Q2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15823" checksum="F70619D5237E2C30" modified="2024-11-27" version="1">MRHFDLCPDAGPETHLGPSLRLIGCRIEKDCVSSDKWNPFPVADRGKRKPRVVCDGRMERVLLSEFCYPYHLFEHNKFFELSPMTPFAKFVACVACHLSIIKFSKCVVNLKKKKQNDHVVKEKKRKKKCEVDFRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XE59</accession>
    <name>A0AAV4XE59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_45831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017650">
        <property type="protein sequence ID" value="GIY93327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XE59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY93327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="21531" checksum="9254F44234BFE794" modified="2024-11-27" version="1">MQRFEKTPEPLNGMKILLVGDPHCGKLRTILALIKCGRLIDISNRHHHKVYTFHYGFCPGKVISLYFPIDNGVYIVNEELLATVDVFVFCFAIDNHESFHSIERKWLPLMKEYLHYRNSILVANKVDLRTCESVVKKKGWNPVSGKEAREMWKRQGFVAYEECSVAQKNVYQILRTAVDMVRNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFW5</accession>
    <name>A0AAV4XFW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_168841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000275">
        <property type="protein sequence ID" value="GIY93527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9763" checksum="22810F7F39A073EE" modified="2024-11-27" version="1">MLHRVYACMSASQSIRKLSPEIHRADELYVCSDYPSLTLNQLTFRLLRMLAVEICENIFGMSPKDRKVDQSSSSPKIDIISETVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFY7</accession>
    <name>A0AAV4XFY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_527071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000353">
        <property type="protein sequence ID" value="GIY94117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19916" checksum="232606DA44128B49" modified="2024-11-27" version="1">MEGVRNGTLLGANGFQSEPEYRTGDFEWRRCLRSLKWLILTRHLQTYLEFKSARLVLSSREFSTAKILSFSQPLSRSESERDSTSREIPICVQLMCIKSNFFPRETLDHQGIERPNQESGSHSTPPGPLECKGLTVLETAAEYARDFWVLFEGEWLGVLLTSFFCLVKESDVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH94</accession>
    <name>A0AAV4XH94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000342">
        <property type="protein sequence ID" value="GIY94033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="233" mass="27518" checksum="1EE63F9BEA024411" modified="2024-11-27" version="1">MHRSRTCPRGLMDKASDFESEDCRFESCRGRLLCNVNYGTGRVFFFLLLFRKLTTISYFTNCYKSNVRLFNITMHRSRTCPRGLMDKASDFESEDCRFESCRGRLLCNVNYGTGRVFFFLLLFRKLTTISYFTNCYKSNVRLFNITMHRSRTCPRGLMDKASDFESEDCRFESCRGRLLCNVNYGTGRVFFFFLAPISKINYHFIFYELLQIEREIIQYNNASFSDVSTWPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIR3</accession>
    <name>A0AAV4XIR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_2071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000350">
        <property type="protein sequence ID" value="GIY94100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7762" checksum="CAAED8F710B38D6A" modified="2024-11-27" version="1">MPEGKSEAFPMLCGLKRIRFTGAGRSIPACYFEITKGSPEQAADYCKKDGGFRGVWKITADDVFPLLEQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKJ3</accession>
    <name>A0AAV4XKJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_613921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017787">
        <property type="protein sequence ID" value="GIY94455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="56" mass="6455" checksum="E84F756F3F65AF94" modified="2024-11-27" version="1" fragment="single">QQTLLSSFVEGRLWPLMEVFKRWLQTPPRSMVLTVMVGQADLANWCVKSSNSSLWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKU5</accession>
    <name>A0AAV4XKU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_335401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000554">
        <property type="protein sequence ID" value="GIY95606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20832" checksum="A35E0EF50FE71123" modified="2024-11-27" version="1">MLWMYDSRLLAAYVHHVIKPVLIYDPVLERHQANFANCYSANLHLLDNEYPETQDVVPSGGRTPSTCTVSYELHRLRSSVGKNNKTGPRSQEMCRAFCRLIYLSECQDCDLNQRVYTESMKLCPYSMDYPNSCVEKLRNDIDECKLNCKPECLKLKYKYAKKQITQNHFLQKLTMGDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLG5</accession>
    <name>A0AAV4XLG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dscam2</name>
        <name evidence="3" type="ORF">CEXT_677351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017834">
        <property type="protein sequence ID" value="GIY94874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="43"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY94874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15593" checksum="68E11CA3CEBE399D" modified="2024-11-27" version="1">MDLMEDTFGFEALYPVVTCGGDLRFETIGSVSVNRTEKDQRGPVFRTEPSSRVEFSNSSGTELRCGADGVPNPRLSWQTREGGNARDVPGLRYTRSDGTLVFPPFARNDYRQDVHDTVYQCLASNSVGSIVSREVHVRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPK1</accession>
    <name>A0AAV4XPK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018114">
        <property type="protein sequence ID" value="GIY97047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8317" checksum="6D70844335712C42" modified="2024-11-27" version="1">MLSNKGYRSLAVAELRNDDENCEDIKSHTAREDFCKCWLVPLIVLSKVNVKPTQHQLAPVSNTRSARKLWFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR67</accession>
    <name>A0AAV4XR67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mab-21 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_185506_1</name>
        <name evidence="2" type="ORF">CEXT_149561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000755">
        <property type="protein sequence ID" value="GIY97224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046903">
        <property type="entry name" value="Mab-21-like_nuc_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03281">
        <property type="entry name" value="Mab-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mab-21-like nucleotidyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="22252" checksum="A7BB63F13A132CBD" modified="2024-11-27" version="1">MYERDYKTGSSYTDLRISEASEYDIDIVLKTPSEIRLEVEFFEATRAFSKIKWSKVSDLSENKMEVLKFLQKNSVDGYVDPVKMTSWLQGLIDVYLKTEPIIPGVKLFKNTQSGPARTIELVTNEDYTIHIDLVPVFMFSNSVLVETPIKSILDTYPAKKKKSFWFLVPKQCRGEEKLLASDCKLSWRCVSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT79</accession>
    <name>A0AAV4XT79_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">cGMP-dependent protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">for</name>
        <name evidence="8" type="ORF">CEXT_684601</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018288">
        <property type="protein sequence ID" value="GIY98410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05572">
        <property type="entry name" value="STKc_cGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000210">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035014">
        <property type="entry name" value="STKc_cGK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF147">
        <property type="entry name" value="CGMP-DEPENDENT SERINE_THREONIN PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="7">
        <location>
            <begin position="197"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY98410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="29027" checksum="F3542B378ED7B681" modified="2024-11-27" version="1">MYKTFRDDKYVFMLMEACLGGEVWSILRDKGNFDDSTTRFITGCVIEALEYLHKRNIIYRDLKPENLLLDSQGYVKLVDFGFSKVLLNGRKTWTFCGTPEYVAPEIILNRGHDKAVDYWAIGIMMYELLTGTPPFCAFDPMKTYKIILKGIDALGFPNYISKNAISLMRRLCRDNPAERLGYQKGGIADIKKHKWFQGFDWDGLKNRTLIPPIVPKVKDHTDVSNFDVYPIMIEDSPPDFSGWDKDFDCNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTA2</accession>
    <name>A0AAV4XTA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_501891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000860">
        <property type="protein sequence ID" value="GIY97952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9120" checksum="71276A10E284FE4B" modified="2024-11-27" version="1">MQSCVNKALCDCGAKVMGALVTLPQLKLLCDYNSEIVILEATLYDFLQANKLRGKKKRRKQDERASNNGRLPFSERSAAISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZC9</accession>
    <name>A0AAV4XZC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_522081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001169">
        <property type="protein sequence ID" value="GIZ00538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ00538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="20167" checksum="ED294313F918F03F" modified="2024-11-27" version="1">MTTFSHRRLSHKNRPLLSSSPQSTAGTPPGSISSLPLLILCSCSSFLPPTSLSLSLSLLFPFKLAVTLAHLYLFAISTRIKQATSRTAPNTRHHWSSIFGQMGNLVPNPCGIATIDSDSPLLRQTQPPTPVRCPPLPLFWTLFNLPVPPVFPPYWSHTADSSARIIHRACAVASYRSIVVQVQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3H0</accession>
    <name>A0AAV4Y3H0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_404621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001248">
        <property type="protein sequence ID" value="GIZ01064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3H0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21435" checksum="5042D003877AEC21" modified="2024-11-27" version="1">MSTAPVICDCFVPHCKYFVFFNKRLFGQGPTMGFWHWAVRRDLCLGPGPGFFCTDARGCCGDTFHHQSFQTLWRKLWPRNGGQCVAQGAWTREIINLTDHRDFRKDVKSDCRENAASLLEIITMQNIEIAKLQGRLMEREESASNKHLSYADKVKMKTTNNTNSKTINNRDRSKSGIRNKTVKSTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8H8</accession>
    <name>A0AAV4Y8H8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_728701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018816">
        <property type="protein sequence ID" value="GIZ02485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8H8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="21534" checksum="1C6C8449DA4A55FA" modified="2024-11-27" version="1">MCSSLPKAPMPTEPKIPGSSQCLWGAQIPPERTREGANERLGVLWVAGGNGSPQTTQNVRGKRIVCLPCLWRRRKLKSGVQKGVAQEEGAPFTEKAQVIRERERSELLIFVIGRPGGEESGAERIPFGIFGTGSWNPICKTKINSTCPTLIALRMIETSHSMSRPPDGTAIFIKNLLPYHHIPIPLYSTLEQPLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y913</accession>
    <name>A0AAV4Y913_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_223392_1</name>
        <name evidence="2" type="ORF">CEXT_126791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001613">
        <property type="protein sequence ID" value="GIZ03503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y913"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="820"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="862"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1163"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="835"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1183" mass="135001" checksum="1D4CB100E5EF7738" modified="2024-11-27" version="1">MSFNFSSTEENNQSSADIIDHEKLMERSLVKECTSGIIEVDEESSIEGSLIKEYSCNKFSSLNKNKQNLINETSEIDHADKLIKGQLIMESVFSPTEESLNSFNEIDHEKSIERSDYNNLIPIEKNTQDSINVNEINHNENSVEEILVKERVNEPFSPLEGNSQNSIKESSDIDHKEKSFVENIVNDSINENFSHFEENSQNSINNANDIVHDNKIIEENLDEGSDRNNVSPTEENGWNSINENDIGYNEISDDKNLCEESNSNNFSPTAENSRNSVNKDDLIERSIEENAFIQNSDSNNGESDSADFSFTVKENQDSVNEVDNFDNENSSDKNLVKKSSSSYVPPSEENSKNYCNENSIDGNLIKNSDSNNLSPSEECSENSTNVIDGNEDNKTNKNVLRKIYNNLSPSEEDNKNSANEVDSINDNESLTDENIDKKSGNNVSLSEGNSQNSINVIDEIDHDEVNLIKECANDNFSFNEEDSENSVNDVNKIDHKDKSTVGNLFKEYNSNSLCSYAENSQNSMIKIDCLSSTEENNQTSISEFNQDPKSADVNLNEFSNSKDDDNALFYESQEDLIENISGTEIDKNLTNEIDGEFDDLMTSNVVSRVSATYKTKRKPSQVSKTSLIDTPKKVLPKSPLKKRPRPSWYENAEVNSIEYVRQWDKFVKSLPTKQNASSEIRKARIKVKQQVETLRKSKNFNSQSNQEISSYKKLNSPILDKDKKLIDKVKISSDKKLNSPSLDLDTSLEDEQYIDSFKFESSPSTSAEVQMAFEYKCLDCCNFSSNRANNLINHMKFCTKPSSVVIAYTEKDMDRRELIRGENFSKSPADGEKGSSSQSLSSTSVMETLVLDESETLKDCGKGDEIIVDEEDDDEESENDERENDKTGKKLQEQSSKTDKDFIVKEIVWTKMNDRYWPSVIAKLNEKKATVFVIDYPKIEFISTKQKEKRLKIDVNEFHDHLHSFKDVTWNKTILDEAEELPYKDLFVKAVQNCASYTRKQFLYNSMYKPVEFFNITENVVVMPGFEDILEDICTPNTNKEQPKRRAEHHNVKSKRKKVNNELIDVKKLLGYIVDGQCNEHIISILKEESKSKRHNLFFLDKPSASEKLKEMSWFSPFKENATMQIELYEYFWNSMKKHLGIIKAISIIKGIKIEEAEHDFNKPDIYETSTEDSGGQKISEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3C6</accession>
    <name>A0AAV4M3C6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Pde11_0</name>
        <name evidence="1" type="ORF">CEXT_765291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001805">
        <property type="protein sequence ID" value="GIX66602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3C6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="429" mass="49145" checksum="03C24A7E90B0F9B1" modified="2024-11-27" version="1">MKRKDTHKPVHKDEPTAATLITNSSAGKNNCVFCDRSHPSQECQKISNMNYDDDRKEQIMRKRCYLVCLKPGHMAKKCHSHVRCLICERRHYVLLCPDLRKGNSSLPKSKVDDEEAKSTENLLTNLSSEYEIYLKTIIVRLRHKGKEACVRALMEDGSHRSYIEKSLVAELNLSPSGTEVLSQGLFDGGISLMSMADFQLRSVTKRLVKENIHEVYDDVLRQWQKEGIIETIPVNEISKPGHYLPRRPVIKSPSLTTKNKFLHPLLRFRTNAIGVIADIKQAFLQLSVRPEDRNFLRFLWWNTEDRSKLEFFRHCRVVFGVTSSPFLLNASIRHHLDSTEYQIESLQATVKKLKRRILYGNFIKATLHIFTDASSHGYACCAFLRCEDEGEVKVSLNSAKARVAPVQRPTIPRLELLGAAIGAKLLRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M494</accession>
    <name>A0AAV4M494_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_327791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001813">
        <property type="protein sequence ID" value="GIX66687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M494"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="12010" checksum="08B11CCD273A41E0" modified="2024-11-27" version="1">MTMCGKNRKRANVISNAGHIIRLRNDKTLAKPPWYFLDITDNKIKSDNKVLVVIHSDNEMKLFIWPHWIRRKSFLIWHASSRKTFLYRLWAFTVIPSTALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4F9</accession>
    <name>A0AAV4M4F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ULP_PROTEASE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_260760_1</name>
        <name evidence="2" type="ORF">CEXT_454461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019337">
        <property type="protein sequence ID" value="GIX66720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="186"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX66720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="317" mass="36483" checksum="11566B2F6ADA2CCC" modified="2024-11-27" version="1">MFESYNDVGRQAVYILDPPITIPASLTMTTFASLHTKNINIPKRNCVGGAPVSIKFLKCEVCKRSYSSKASFSNHLKRFKCLQPGFRGHRSFVPSKEAFISRSIRTYYRRLQNSVRPENDALSVMSNAERLKAEEYNPILLFKPQNSKTLYGPPGLDALLNSDKSFALGIQTETQKEMLVKHSYKIICIDSTHDTNRYGFYLLSIHIQDEYGQGYPVAHFICNYLDYDTLITLFNSLKCRISNLRVYNVMTDDDNVCYTAFNSVFGPNLNHLLCKWHVFRAWNRQLACKVHSNDLRNILRKKLNKILNENATQILKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAH7</accession>
    <name>A0AAV4MAH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Ero1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">Ero1L</name>
        <name evidence="18" type="ORF">CEXT_50561</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001905">
        <property type="protein sequence ID" value="GIX67814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 16" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="16">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="17">
        <location>
            <begin position="96"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="138"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIX67814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="452" mass="51958" checksum="EDD3A46A91423C67" modified="2024-11-27" version="1">MSIITDGASKFLSSPHFILKTDYIDLVSCTVYSSGGCFCKLEGRIDDCSCNIDTVDHFNNVKLYPILRSILVTDFFRYIKVNLNRGCPFWPDDSKCAIQDCSVKACPEEQIPPGLKGHQTFKIDSEKNVKPTQADEPCDENHGGLGAINQTISDENFEDFQRWQKHDDSIDTFCEMDDENSLELQYVDLLLNPERYTGYKGSSAHRIWNSIYKENCFRFGGGYGPYTTSKNLEALCLEKRAFYRAVSGLHSSISIHLCAEHYTKARDCFSKGEWGPNPQEFKRRFDPTLTDGEGPQWLKNLYFIYLLELRAIAKAASYFENELFYTGNEENDKQVQVTIKKLLETAKSFPDHFNENVMFSGNDKETRKLKEEFRLHFLNISKIMDCIQGLGTAFKILFSKDLSTNFSVHRKQFRLTRTEVVSLFNAFGRLSNSVYHLDKFRQILGSNQKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBG5</accession>
    <name>A0AAV4MBG5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_550291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019558">
        <property type="protein sequence ID" value="GIX69228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11991" checksum="5C793D52312D9CC7" modified="2024-11-27" version="1">MINAFTATNIVWAFESDQPITMLKRPFRSKEWMGRKMFEPHPLLKKKEKRMLFIPKLFTWNLLVNMGCLSDSSTLNNAVEGTCNFESDVSTERGMAGSEPDILSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD49</accession>
    <name>A0AAV4MD49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_133491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002131">
        <property type="protein sequence ID" value="GIX70344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="782"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="882" mass="96831" checksum="D5B65C77812EA2EB" modified="2024-11-27" version="1">MRAANNGMFDGDLTCTCGKGDPYANYAIPRSAAMHPNDISMASGLPNSGKDVKTHAADPTEDYDVPKKFTDLMFNCDMTQKSSAMKTISNGPSCSCMSACKMVQNIELFKMASKHSYNHKHGPMSSNPNDGLQMCACQRVMLWAGSLVPCLGPQRATMETGWQCTKSLSTDGCPRKWMNHATAVCSEPHRTAEVVMKNGKPKHILRESSADIPYTSETNYANIEFPSNPDSKSVKVTDDGSSVNYANIEFAETLPLYENSNLVLSRLESEDKKEPIVPNKPPLPPRCHMNAGKKLSDALDKEDKCKCKPSVNRSPKKTVDRQMNGGSAYEMMCYEKNPMYGQNDEDYLMMQPLCIKDEKSSSPSKQISAGSVETVPVSSISIQNGESEVQENLPLRPFMPYSYPIVEALGTSVPEDISGDSMLRKNQLINEDLHLRAMRSNSLSELKKKVLMRKRSSSVDGKNNGYQSKDSGVESVPASPVGSPRPSMTRKNSLFSKLSLRSKEKSMSTNEIDLPLPIPNGNQCALNTIHKNGHHRSADCLKQNEEFTNSDEDLNSDSSDFILQKETHSPMKRSSSVPCRAALPVVSISSPVRTNGTIMELNDLNKEASQSVPEGAEDSQEPVQRKYSLDSHERSKPRVSYKVGPNCDNIYSQECLDESDTVMEMQGILRRNHTHTLERGPVMDSYRSNTSSCSSSDISDYMESLSFISRSSSSSSGSTSSADYMRSEDLYGLRPLPRPPPKGAMSGSNNITIPNIHQSRHCPLDMNGVATRYRSLNEPCEPSSVGTSSGPSVQDTAYYQGKDESHVRPCTSIRCNRDSRSSTSSTSSLSTSPSVTDYSSSTSSSPPCLTNLPAKQAFVKRKPEVKPEGQATSFAYPPTQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJ34</accession>
    <name>A0AAV4MJ34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">U19-ctenitoxin-Pn1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_240041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019851">
        <property type="protein sequence ID" value="GIX72502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJ34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043517528" evidence="1">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9082" checksum="0E1259E3EEA42742" modified="2024-11-27" version="1">MRGIFAIFLLACVVFVGISAEGCGTLESCGEGQCCAGSFYHRFCRDLSDDGMPCEQPNRAEHYSVACPCKEGLVCNVLPRCQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSZ5</accession>
    <name>A0AAV4MSZ5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FERM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PTK2</name>
        <name evidence="2" type="ORF">CEXT_670841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020121">
        <property type="protein sequence ID" value="GIX74990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13190">
        <property type="entry name" value="FERM_C_FAK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049385">
        <property type="entry name" value="FAK1-like_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041784">
        <property type="entry name" value="FAK1/PYK2_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21477">
        <property type="entry name" value="FERM_C_FAK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="17906" checksum="958B61CECA3DAA70" modified="2024-11-27" version="1">MIQNQFKRFASLSEVDCMFMFLDMVHPVVKYDREIFKCALGTGWSVPVELVIGADTGISFLTDPNAVVSILIALLFLADIYGKLPKVQSINTVVTPDGSKPVLQLKIDGTAEMLSISCPSTNIAECIASLIDGYCRLVHGTKLHFGIIQIQRSQNLGTEVTEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTD4</accession>
    <name>A0AAV4MTD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_223891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020189">
        <property type="protein sequence ID" value="GIX75685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13607" checksum="6DDE343499675641" modified="2024-11-27" version="1">MSSVNKILISRPALRKVCVNFLPTHPLFSHPFLPESPVKRIGAYNHPFPTPYPPPGIPLLSWHSRMRINGTGSNEPEKFAAECGTVVWPRQGPDIFALKECNYCNYLDEITQALFSEIGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NC42</accession>
    <name>A0AAV4NC42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 12 member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SLC12A2</name>
        <name evidence="8" type="ORF">CEXT_37031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020766">
        <property type="protein sequence ID" value="GIX82292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NC42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008511">
        <property type="term" value="F:sodium:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055064">
        <property type="term" value="P:chloride ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055075">
        <property type="term" value="P:potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055078">
        <property type="term" value="P:sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000022">
        <property type="entry name" value="Bumetanide-sensitive na-k-cl cotransport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF103">
        <property type="entry name" value="SODIUM CHLORIDE COTRANSPORTER 69, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="35"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="7">
        <location>
            <begin position="514"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX82292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="685" mass="75316" checksum="CC60D4EF70A9CD50" modified="2024-11-27" version="1">MFIFGVSLRISYFSRRLSKASTEKQAAVKFGWIQGVLVRCLLNIWGVMLFLRLSWVVGQAGIGLACLIILLATAVTVLTTLSMSAICTNGEVKGSLGPEFGGSIGFIFSVANAVAVAMYVVGFAETLRVLLTNNDLPLLDNGINDIRIISCVTVIVILGIAIVGTEWETKAQIILLLILLAAMADFLAGAVISPNEEQIAKGYVGWNKTVFIENFGPHFSEDQDFFSVFAVFFPAATGILAGANISGDLKDPQTAIPKGTLLAIFITTLSYILFVVVSGSIVLLDSNGIVDFVSNGTLEYLTNCTFGEKNKCEYGLLNDYQVMEMVSAFSPVIYAGIFAATLSSALASLVSAPKIFQALCKDKLFPGYLLAFVIALGCCAIGDLNHIAPLISNFFLAAYCLINLSCFHSTFVKAPGFRPAFRYYSMWLGFLGAILCLLVMFIINWVTSLITFAVVFLLYLCIYQRKPDVNWGSSTQAQTYSLALNAVMKLNEVADHVKNYRPQVLILTGHPSHRPPLVDFGYTITKKLSLLICGNVITKEHLNHKTRTGMLELGHKYLRYRGIKAFYSAVEDTSFSRGVASLIQVAGMGKLRPNMILMGYKNNWETCAHEEVQEYFNVIHNALDMHMSIGILRLPEGMDYSKYAAQLEDYAVLSKKEKKKRMKAAEFNDENGMLRNKSCSELSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFN2</accession>
    <name>A0AAV4NFN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003339">
        <property type="protein sequence ID" value="GIX83536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12458" checksum="BDDD929337F4503F" modified="2024-11-27" version="1">MDPNTGTNMEMAMAMYREAMASLIIGGSTEKSTTWLTSKDLQSYCEDQRAQELLIKTLLMSSFIPTPIMLSIMMDTTMDTISKSIIIMAITTMACSSVSSSTASSSWSSSWLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJT8</accession>
    <name>A0AAV4NJT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Laminin subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LanA</name>
        <name evidence="3" type="ORF">CEXT_254871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003410">
        <property type="protein sequence ID" value="GIX84201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050372">
        <property type="entry name" value="Neurexin-related_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036:SF67">
        <property type="entry name" value="LAMININ SUBUNIT ALPHA-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036">
        <property type="entry name" value="PIKACHURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Laminin G" evidence="2">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="2">
        <location>
            <begin position="175"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX84201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="293" mass="33076" checksum="C26A9262406062FC" modified="2024-11-27" version="1">MSLYFKTTERYGLLAFVGNEKGSHNRMKRVLTDDYLALEIRGGYLVLIMDLGSGSQNIKHDTYVSDGKWHQAVIERTGKTCSITVRSGDENDSVVEGFLPGTYSVFNLDQKVSKFFVGGVSDKLQLPDTLENYHFDGCIEDVEFGETPVGLWDFVFAENNIEGCEERNELAVQPSNGLRFSGAGYVILPRKRHQFASETTIKMLFKTYAKDGLLFLIGKNNDFFALEIQDGHIILKYNLGTGLATLKSPDTYNDGKWHSWEAARFDKDAVLKVDQVEVDSAHITRRRNYVVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NL97</accession>
    <name>A0AAV4NL97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_619431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021073">
        <property type="protein sequence ID" value="GIX85582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NL97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="20558" checksum="0220D15793F01E71" modified="2024-11-27" version="1" fragment="single">MQKHCGSSLFQALFVKQIPDILGLARDEMKVEFKTESMKLSLHYRHHIMGSQAYLKTALDLRNIKYGDECICLEKQKYQVKINERETPTQKQCGSSLFQVVFVKQIPDILGLARDEMKVEFKTETEALRLFFFQLLFVKQIPDILDLARDEMKVEFKTESMKLSLHYRHHIMGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQX4</accession>
    <name>A0AAV4NQX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_161971</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021201">
        <property type="protein sequence ID" value="GIX87073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX87073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17783" checksum="DC02B58CB0FF493E" modified="2024-11-27" version="1">MRGRNKAGHESRCMGQITPSILGYFSGCLYQSWSFLDIYFKYPTTMEVSVEQAPVLQFPAVTICNGNRIGRYFNYEYTNCFSINARWANRSAELFSASMFRPRSGRSSELSIMLNLERNRYSPMNPVVRARMTIHAADTIPNPQYDGVSLQPGIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRQ6</accession>
    <name>A0AAV4NRQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_132941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003543">
        <property type="protein sequence ID" value="GIX85812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9074" checksum="AEB647818594A9A8" modified="2024-11-27" version="1">MQHQVFITRRVQNEMPLSSSRGHQVPEPLLSAYCLEGVDKQHFLFEGASYRYRYLPSEISSREIRTFELSFDIHLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSH4</accession>
    <name>A0AAV4NSH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_10931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003624">
        <property type="protein sequence ID" value="GIX86871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12411" checksum="3BF1D3FC5146BCD3" modified="2024-11-27" version="1">MSDGCPFFVGKLASRLHTLCKDGGDKSKDSGCAWTTKRLSLKLVYPRDVSRWNNTMTNPFFSFENLISRYDYAGIFCNTTSYIMVHIGNIWLSSSDAWHFCRISHASDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NW75</accession>
    <name>A0AAV4NW75_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AASS</name>
        <name evidence="3" type="ORF">CEXT_594641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021396">
        <property type="protein sequence ID" value="GIX89155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NW75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004753">
        <property type="term" value="F:saccharopine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000087">
        <property type="entry name" value="alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="2">
        <location>
            <begin position="49"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX89155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="320" mass="36024" checksum="5F0BF89B42CD0E89" modified="2024-11-27" version="1" fragment="single">MYSHRSDLQAVTISKMWRVIRENKTFASYVYKAKTKSAVRQKSSGKVLAIRREDASVWERRAPLAPFHVKQLTKEGVKVLVQPSNRRAYPMQAYINAGAIIQEDISESPVIIGVKQVPIDALLPNKTYCFFSHTIKAQETNMPMLDSILERNIRLIDYEKLVDSKGQRVVAFGKYAGVAGMINILHGLGLRLLALGHHTPFMHIGPAHNYRNSGMARQTVRDSGYEIALGMMPRSIGPLTFVFTGSGNVSQGAQEVFQELPYEYVNPTDLPQVAEHGSMNKVYGTVVSRDDHFRRKDGGGFDAEEYEAHPERYYSNFAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZN0</accession>
    <name>A0AAV4NZN0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_679861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003812">
        <property type="protein sequence ID" value="GIX88991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8040" checksum="720F73F6ADBCB87C" modified="2024-11-27" version="1">MMSGRRVEQPIIVQVTTVTPIKSFFNAVPMPRWTNGQLGNLLASDLKESDFFSIYSTLLSGGMTNSPARSSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P010</accession>
    <name>A0AAV4P010_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_547971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003873">
        <property type="protein sequence ID" value="GIX89541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P010"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8366" checksum="E2EBC8D263C8DB4F" modified="2024-11-27" version="1">MKSPAHKRLSKVMEVDFVAVSKSKRLICRQLTCGWIGVLMDCKSKRSTNRKMTACFFPILKEIEGRSGVECEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2G1</accession>
    <name>A0AAV4P2G1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_532401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003901">
        <property type="protein sequence ID" value="GIX89951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8939" checksum="167F0E4D7981F8A1" modified="2024-11-27" version="1">MWNLPFKITYPIEYLHHSKAVTNSKSHGDISSDYIEINLQSHFLVDLMVMIMMLMRMMVAIIVIMIINMTSCCSVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P548</accession>
    <name>A0AAV4P548_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_262421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004011">
        <property type="protein sequence ID" value="GIX91311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P548"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10320" checksum="11E4896662EE137F" modified="2024-11-27" version="1">MVAKALRNLTMVDVVTEDYIATRMDIVNTKKVYAQHEHKKDINRLFNERIFFMLAEVFVRELSAVDDRVPRSIMSYSSSSAELICREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7Z9</accession>
    <name>A0AAV4P7Z9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynein heavy chain hydrolytic ATP-binding dynein motor region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_802861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004207">
        <property type="protein sequence ID" value="GIX93166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7Z9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46961">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46961:SF19">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 5, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8097" checksum="5D2CBAAF3A047782" modified="2024-11-27" version="1">MLHIISLAQALQMHLGGAPTGPAGTGKTETTKDMGKMLGSMLSSSIVPIKWIIKDWDEFTKVSLSPDPGVALMSLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PC59</accession>
    <name>A0AAV4PC59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_108781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004267">
        <property type="protein sequence ID" value="GIX93575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PC59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11881" checksum="3BD965AC206C1E14" modified="2024-11-27" version="1">MFEKKFFYLPICRFLANHLPLRQILIKTERSPRSATNPSKKRTSWRQARFSATDLRNVTKAQKLDAFTRNGRECFLIRALPNRFAVTYHLFFVGEMMNHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PFS0</accession>
    <name>A0AAV4PFS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_156727_1</name>
        <name evidence="1" type="ORF">CEXT_442721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004463">
        <property type="protein sequence ID" value="GIX95016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PFS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="375" mass="44505" checksum="F73F320D593C491B" modified="2024-11-27" version="1">MFKRWTQPFRTNFSTPLKISHLCYRIADIKQAFLQLSVRPEDRNFLRFLWWNTEDRSKLEFFRHCRVVFEVTSSPFLLNATIRHHLDSTEYQIESLQATVKKLKRGFYVDNLTISVENQQELLEFKAQTMKIMNAASFELRCWAHTGTKHSETQNVLGLKWDTETDELYCVSPETDMGISDNISKRKLLSIVNSIYDPIGFTSPATLLPKLLLQETWRNKLDWDEELTLDIQLRYRRWAKHIALIEKCRIPRRILYENFKKATLHIFTDASAHGYACCSFYDVKMESAEEALIRIIQSEWPTDIQEKYAQTIQFYEENKILKVKSRLILREDPEDFVRPTVLPDHPIVRRLIDYVHQKLQHAGVQTTLSHLRERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQ04</accession>
    <name>A0AAV4PQ04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_542621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005012">
        <property type="protein sequence ID" value="GIX99174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQ04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10718" checksum="B43223E10E71B053" modified="2024-11-27" version="1">MKPHQNNRHFSLQDKHPKKTLDDTRTVSATDTDVYHMVFLKRMSLWRRRMSSRCAMSGWTILSLFQAILSHANLIPRGGRTKKKNRLFHPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV81</accession>
    <name>A0AAV4PV81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_606051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005242">
        <property type="protein sequence ID" value="GIY00964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12177" checksum="FB3CD9E8DDE30CAD" modified="2024-11-27" version="1">MESRDGSSPSNGGPPFAFVEGLLMLLKCWGHSLLQLHPYLRIDCICWLLSKIGNVYYSAGERWNCVILDQIWPNDDCDMQMDRSVRCRHCQPLLPVVVEYLSMQCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWY7</accession>
    <name>A0AAV4PWY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_56871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005390">
        <property type="protein sequence ID" value="GIY01933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16444" checksum="AB114D4D39FDB289" modified="2024-11-27" version="1">MKLTTIKTHTIIKCFKWLNEHGEPSHSCTPNPRCQARNLSHDLKPQKKQYTRNDGRKSSNVSRKHLCQHLKINKIKAFPNALSAEPVPYVSGLADFVPLGFLKDVACFLFTKLPCPLVVEKERKKNFANWDIQQPVEYRRTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q294</accession>
    <name>A0AAV4Q294_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PTN_MK_C domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_198055_1</name>
        <name evidence="8" type="ORF">CEXT_495452</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pleiotrophin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005451">
        <property type="protein sequence ID" value="GIY02502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q294"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008201">
        <property type="term" value="F:heparin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048332">
        <property type="term" value="P:mesoderm morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.90.10:FF:000001">
        <property type="entry name" value="Pleiotrophin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.90.10">
        <property type="entry name" value="Heparin-binding Growth Factor, Midkine, Chain A- C-terminal Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020090">
        <property type="entry name" value="PTN/MK_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038130">
        <property type="entry name" value="PTN/MK_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020091">
        <property type="entry name" value="PTN/MK_diS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21050">
        <property type="entry name" value="MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21050:SF1">
        <property type="entry name" value="MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01091">
        <property type="entry name" value="PTN_MK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57288">
        <property type="entry name" value="Midkine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Pleiotrophin/Midkine C-terminal" evidence="7">
        <location>
            <begin position="155"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY02502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="274" mass="30872" checksum="5A1118CBEC2172DB" modified="2024-11-27" version="1">MNGGLIPLEWKQTVENKNKETRVPGMESTLYLGKKASNLDGWSFSTRSIFFCSGLTKSSAGKMKVYLTVCFMLSTFILIEAVGHFHDELFRDSDDQEIVYRVTRGAHSKKKDGECRYKKGPWSECDSSNMQKKTLTLKKGDSSCEQTKVISRKCKKACKYDKGDWSECDVSSNTRARTDSLKPESDSSCDPTRTISKKCKKVCRYSKQAAWSDCDPATGQKTKVLVLKKFRSEVAPQQCEANKKITKPCHKGSGHKGKGRQGKGRIHIDYDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBD8</accession>
    <name>A0AAV4QBD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005945">
        <property type="protein sequence ID" value="GIY06301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7774" checksum="A736E12D2A34BFFB" modified="2024-11-27" version="1">MITYVARYLVLGMNQSSLNRAYSQPIGGKFQTTIILLPAFELSDLVWRTNSSRAFQAPSRFLDTMEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBV0</accession>
    <name>A0AAV4QBV0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">inx2</name>
        <name evidence="12" type="synonym">inx</name>
        <name evidence="13" type="ORF">CEXT_432371</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005998">
        <property type="protein sequence ID" value="GIY06772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF41">
        <property type="entry name" value="INNEXIN INX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY06772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="364" mass="42526" checksum="14E7455D943FB7A6" modified="2024-11-27" version="1">MDRLFESLKGVLKLQGVTTDNHVFRLHYKVTLPILVAFSLLVTSRQYIGDPIDCISRDDIPPQVLDTFCWIHSTFSLENAWFKKVGSEIPYPGVDKYTPGEKRVYHAYYQWVCFVLFLQAILFYVPRYFWKCMEAGKIKAMLMELNNPVLNEAKREANLRLLVDYVIANFNHNDGYSVFYLLAEIMNTVNVIGQMYLMDTFLGGAFSSYGTQVWKFSDWDWTLRYDPMIRVFPRLTKCTFHRYGSSGDVQRHDAMCILPINIINEKIYVFLWFWFVVLSVASCIAVLYRILLFVSPDARMRALKPRAGVAREEHLEIVLRKCKMGDWFVIHLLAKNLHSINFRDFMSNLSRRLEGKNYSDASEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCW9</accession>
    <name>A0AAV4QCW9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acyclic terpene utilisation N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_150946_1</name>
        <name evidence="2" type="ORF">CEXT_317511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005907">
        <property type="protein sequence ID" value="GIY05951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47708">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47708:SF2">
        <property type="entry name" value="SI:CH73-132F6.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7808" checksum="2223176B6D0203B1" modified="2024-11-27" version="1">MSSNIRIGCASGFWGDTAMSVPALVHGGQLDFLVFDYLSEITMSLLAKAKQNLLIWAIHQTLFILQWPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6J9</accession>
    <name>A0AAV4R6J9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_479141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007287">
        <property type="protein sequence ID" value="GIY15822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6J9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18779" checksum="DFACBD89D0CAE441" modified="2024-11-27" version="1">MSSAESPQKRHRMNDFSIRDCQHPLFCKGNRTISSIIQMCVTVTLFFIFFQRGMASILPFVTFRDLVISAVTCHLLGIDRSRMSRRRVTKPPMRAVCRRNLACRLSEKEYWVKEVGVRVNTSSVRARHLLADVISVTTGNWFMKLTFLTSHQNAYHAEARLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFX6</accession>
    <name>A0AAV4RFX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_780331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007691">
        <property type="protein sequence ID" value="GIY18903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9785" checksum="0AF59D83E01AE918" modified="2024-11-27" version="1">MSSGIKNDSWQLSQETLTSQRKRSRQMDRTCWKNVFFFQEWVCVTVYQVHLTDDDMHCFGRCLKIIRRNSRIDNACYQNET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJP8</accession>
    <name>A0AAV4RJP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Techylectin-5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_20341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007990">
        <property type="protein sequence ID" value="GIY21254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143:SF458">
        <property type="entry name" value="FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="2">
        <location>
            <begin position="190"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY21254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="398" mass="45641" checksum="24E908DBBA528F62" modified="2024-11-27" version="1">MTWIDASFFREKLKGFFTTQPFLRAECSKIARTASALLAPVQDSAHFKNITFDCQRVSVFSVAFRFILRRSLYKKLKILKMVQRQNFYFYALSILTLISISYASINDTTLCGTVEKALALTEIAEDMLIKARNFYPVCDDGAMHPPPCLTRSRLENYLTSTRNVISEIKSTIPQSNSLESINFLNRLKRNDSESKPRDCSAVLASGQNKSGVYTIWPIVGTKIKPLNVYCDMDTDGGGWTVSLISFNRYWREYKIGFGDVSKDFWLGNDNIYALTNQERCEIRFDLEDDEGNKRYAAYKNFRIDDEQSNYTLSISGYYGNAGDGMKFHDGQRFATRDRDYLTGAAVLEGAWWIFGWAYCHLNGLYIPGIDDPKSIHWYLWKKNVGLASAEMKLRWTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RK83</accession>
    <name>A0AAV4RK83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_773921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007947">
        <property type="protein sequence ID" value="GIY20897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RK83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13713" checksum="2AEEBFCEBC161058" modified="2024-11-27" version="1">MWMLRDVSAQCIRARKALATFSTFRFIISVHRAYMAQFVTVRKALIAYKILRTCSRRLSRRENIDHISYMDAADVFQRISTFRTFIRIFTTVNYADVFVQYGTLRKAFTTFRTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPT1</accession>
    <name>A0AAV4RPT1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_82802_1</name>
        <name evidence="1" type="ORF">CEXT_428951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008153">
        <property type="protein sequence ID" value="GIY22472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="12101" checksum="4742DA2F8F0E0557" modified="2024-11-27" version="1">MDERNIRFNYDYIPTYIRLDVSPEDSFNIGKHFGSLTTHNLILPRPNEIRTLHLPHANDKMIDRMPWLNRQMHLQGRMDHELWKSLQNRESRLQPRASGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVN4</accession>
    <name>A0AAV4RVN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_527581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008443">
        <property type="protein sequence ID" value="GIY24744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11167" checksum="333AA474776890FA" modified="2024-11-27" version="1">MEARPPRILTIVLQNEGPECYCRLMIMSAPALHNPLRERHSFCNFNSPFAFPIHPLKHSPFCSGGPHKLLFTDWRKECKYHWKRLYQMEVQREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2G6</accession>
    <name>A0AAV4S2G6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_473321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008825">
        <property type="protein sequence ID" value="GIY27524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2G6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10220" checksum="A434FD68B299786C" modified="2024-11-27" version="1">MTASFAVPEVMGVEGGCSNVDAVTGIPERRGRLPANERPRKVMNKDWPYRSAEAVFVCLPCMDDGGMLLQKMDTFSDLGNHIKNLHLVATKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6I5</accession>
    <name>A0AAV4S6I5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_658211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008834">
        <property type="protein sequence ID" value="GIY27618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6I5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11702" checksum="0038E9C539374B0D" modified="2024-11-27" version="1">MQDTIPVPYHSKSIKSIRIIPTVCWESFSFMSNGSAIFLLLFSGKVNIGAGSVFVNVSLPKESALVFSLNVALFCNCLMQLLAALFLRQKCLAGSLTSARDLIKRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6Z6</accession>
    <name>A0AAV4S6Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_78651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009201">
        <property type="protein sequence ID" value="GIY30278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13556" checksum="A2B93C79AE4EB1B3" modified="2024-11-27" version="1">MNRRNHTKSLTLLNDDSTPWGPTTRSSHPPSSNNFCSMTNQPQSYIPLELTEMKKRRNVFFSFVLLKVECSMSQSNGTNFVECASWWMAGNWRFIKWINPKRELQCIIQQVLNDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8J7</accession>
    <name>A0AAV4S8J7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_92631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009111">
        <property type="protein sequence ID" value="GIY29684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8J7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10121" checksum="DC3DAC5BD83ECF98" modified="2024-11-27" version="1">MKCLREIMMFEENQIGWPATFLSISSQDYHGAPYQTLDLHAITPQPRPLAPSSPAFFHRETPPGVISRDDICRKWLPNRENDRHFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDN1</accession>
    <name>A0AAV4SDN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_796731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009241">
        <property type="protein sequence ID" value="GIY30507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="13059" checksum="2A551389E2F6A0E1" modified="2024-11-27" version="1">MIKQSSSDKWRASHVVWTRFSENFPQYRTIECKTFQWRKDDDRILLRVPILFQLRNYTKAKKFQQSYIWKSLFQNVPLTVNDSLLGLFGKTWVHIPQHTRISPTIFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SID0</accession>
    <name>A0AAV4SID0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transposase IS30-like HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_148040_1</name>
        <name evidence="3" type="ORF">CEXT_159231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009537">
        <property type="protein sequence ID" value="GIY32724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SID0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase IS30-like HTH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY32724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11001" checksum="1BECAE649A980517" modified="2024-11-27" version="1">MDLKGKGITPEERKIIIKLRNEGKTLREIGKIVGRTHSSIQRVINNYTSSKFIISKPRSGRPSKLTAREKRYVFKSNGITFLLRRPPYSSILCPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMX4</accession>
    <name>A0AAV4SMX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_699341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009581">
        <property type="protein sequence ID" value="GIY33018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13338" checksum="0EC8DEE2980BABC3" modified="2024-11-27" version="1">MALSEKQNFKETEQDIIITWFSFVLSAPPADGTGDAGHREDAHFRGQPHGQLLPQPRRDGHRQAEDVPDDPQPLLRQHSHTPHGRLAPLHPLRRHPVPNDAHSEWDLESPKDESWNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQM0</accession>
    <name>A0AAV4SQM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_150991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009921">
        <property type="protein sequence ID" value="GIY35511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13943" checksum="B4120181D6A0CF8D" modified="2024-11-27" version="1">MLRRHYYSFHNPKKTAPSMGTALDIYHVKTYRYTKPSKPHSRSSIFQKTHSQRYTRLCRNRMRRKADSILALCPAKLAKGGALEVTSAIVRDVLSRSHISSTVFFAVMAIGQLVPRPRLPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SV90</accession>
    <name>A0AAV4SV90_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tenascin-X</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_662981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010154">
        <property type="protein sequence ID" value="GIY37312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SV90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="27900" checksum="8743B1CAD9CFD461" modified="2024-11-27" version="1" fragment="single">CDCGENGTCSFINGLKRCTCENGYAEVNGVCKECDCGENGTCSFINGLKRCTCENGYAEVNGVCKECDCGENGTCSFINGLKRCTCENGYAEVNGVCKECDCGENGTCSFINGLKRCTCENGYAEVNGVCKECDCGENGTCSFINGLKRCTCENGYAEVNGVCKECDCGENGTCSFINGLKRCTCENGYAEVNGVCKECDCGENGTCSFINGLKRCTCENGYAEVNGVCKGALAKTVMQRLMEFAKNVTVEHGEWNMQFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SW62</accession>
    <name>A0AAV4SW62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_28491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010175">
        <property type="protein sequence ID" value="GIY37501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SW62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="21972" checksum="137047E736545C1B" modified="2024-11-27" version="1">MGVSIFEVHGYSQSFIRIPYPHPAILMGVNAHFIVCITHFALTFPAIQRGGHSSSNYFNPSSPPMVIYLTKICLFKHNPYKNEKGRDPLNTSLLTIETDPGWQTGGGTVNCQVKKNPCLLPEGRENSLSKIPLANAAAAVFLFRPQGQQPKASCLAKQQAVSSATNAILSRRLKRGHLFFGKGCLLFHYSVFIASHKSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWJ8</accession>
    <name>A0AAV4SWJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_99671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010112">
        <property type="protein sequence ID" value="GIY36942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="12207" checksum="C5E8A12621371B88" modified="2024-11-27" version="1">MGHRWPISLSSYFATTPQVCHLEVPILFLESIERRFHPINLKRNNTKRIREKRQRIIEQRQRMFQFGFACRISYSTVNVLSTIPHYISFYNLCQHKNVVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXW5</accession>
    <name>A0AAV4SXW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_59531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010439">
        <property type="protein sequence ID" value="GIY39268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12861" checksum="E8B4DA90ABCBE72E" modified="2024-11-27" version="1">MTAGITPLTPPTMVLNAFDLISKAMHLRLKLFKIQLYRIQKKSLTLAIILERLEQLMQANDSLLIGHGLFILSIFAKMWDITGTVSDHYQIFLRTSSHPALTNKDKDNNIKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZ56</accession>
    <name>A0AAV4SZ56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_789691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010286">
        <property type="protein sequence ID" value="GIY38306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZ56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8257" checksum="8096C770EE741E17" modified="2024-11-27" version="1">MSEEGSFHIAMPSRMKSEIAKEEDGVNATDQRINAVLSLTEESFVRKLHRCYLNFRCVVVLQLQGLRSGSGGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2F0</accession>
    <name>A0AAV4T2F0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein diaphanous homolog 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Diaph1</name>
        <name evidence="6" type="ORF">CEXT_423531</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the formin homology family. Diaphanous subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010366">
        <property type="protein sequence ID" value="GIY38862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2F0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.40">
        <property type="entry name" value="Formin, diaphanous GTPase-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044933">
        <property type="entry name" value="DIA_GBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="5">
        <location>
            <begin position="46"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="362"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY38862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="503" mass="56676" checksum="487436FDA9452D7F" modified="2024-11-27" version="1">MSAKDKRSGNLFSGLGKKKDKAKWAHTQRPHSDDFTDQVQNDGENLDHLTDEQINLQFEMMLDDMNLTEENKEPLRNKGMAEKKLLILHMKKTTVKNRLDSPADYISYLSNSDLSVHKLFQCLESLRIALTNNTVSWVQDFGSQGLDKLLQILNLCYGKNAKYERVQHECIKCIKALMNNTVGLKQIFKHPDALNILARSIDSSVPVIMTDAVKLMAAMCLVPPNGHEKALEAITVCGEIEGRERFAPIIRGLETRNETLRIACIQLINALVTSPDDLDFQINDCYDLIRQTIGETPAEADFLSILQHLLCVRDDITVRSAYYRLIEECVSQIVLHKNGCDPDFRHTKRFKIDVEPLIETIIDKSKQEEERVSDELSKKLEEALTAKQESEAKLSQVENRLREYEAIISEVKKGGKLPQLPAGFLANMGSSAPPPPPPPPPPGSGIPPPPPPPPGSNIPPPPLCLGWEYPLHLLCLVWDLHPHLQCLEWEVHLHHHLLQALEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4Y1</accession>
    <name>A0AAV4T4Y1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_293111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010513">
        <property type="protein sequence ID" value="GIY39800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4Y1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9192" checksum="257BA0EE4AE12984" modified="2024-11-27" version="1">MSYVVVCCDKMLLYIVIKISHIEQPARRHRSTRTTSNALFIRMHIRPVPPLNLSSEKRLKDIIFVYPLVVSCTDRLHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T6X7</accession>
    <name>A0AAV4T6X7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_747821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010699">
        <property type="protein sequence ID" value="GIY41211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T6X7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19481" checksum="2AD90C04C32B7EF8" modified="2024-11-27" version="1">MDHRLHQTSSTLSSRVHPRSNTTHFEFGDVTPSAAPSFPSPKNPLNNRLALPTTPPILSGPRDRTCLISIYVAEDDGVFVLTHSPFRPSLGVHGPQIKTSKRSFFFPPSLNKKNVRIAIGADWNWIHISGRVGFGISAPKSDRCDCCKHGKESPLSLIYTLGLKLKNSRKMRTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TC83</accession>
    <name>A0AAV4TC83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_596311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011113">
        <property type="protein sequence ID" value="GIY44243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TC83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9921" checksum="F99BECC524AF7244" modified="2024-11-27" version="1">MHRKNRFNLSGEKGDFIDPLHPHTPAVPLVDFLGELRESPVDAAPHESRHSPVMILVVRFRGPERYSTQSCAVTPVRPIPEKRKKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJB7</accession>
    <name>A0AAV4TJB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Juvenile hormone acid O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">jhamt_7</name>
        <name evidence="1" type="ORF">CEXT_499001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011259">
        <property type="protein sequence ID" value="GIY45309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="GIY45309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="23900" checksum="3405BBC61DFD28AA" modified="2024-11-27" version="1">MLEFAKTNNFHPKIEYSIGDIEEWSTVEKWQGQITKIVSIHCFQWLKDKKKGFYNVHQLLKTGGEAAICFYADSSVYKSILEVKKKPKWKDLFQDVDDYVSDGYIYKHDCLHYKKMVEEIGFHVLHCTEERKIDTLSSDEEYRSFFASICVLTSHVPLHLKEEFKDDLFDEMLKENGRGENGLPLYGSKLIEIVVKKNSDENKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
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    <name>A0AAV4TLP0_CAEEX</name>
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        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
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            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
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            <taxon>Arachnida</taxon>
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            <taxon>Entelegynae</taxon>
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            <taxon>Caerostris</taxon>
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        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="protein sequence ID" value="GIY46021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    <sequence length="75" mass="8634" checksum="5A816D6F3F9DB0F7" modified="2024-11-27" version="1">MLVITFLKKKKRRKNRISHLDRKTEGRTPEKINFCRAMPIPSRRDLSGSCRRLAADEGLAEVNAAEREAPSIQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
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    <name>A0AAV4TMJ3_CAEEX</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CEXT_241511</name>
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    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="EMBL" id="BPLR01011399">
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            <end position="194"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
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    <sequence length="194" mass="22341" checksum="BFEE142B11F23303" modified="2024-11-27" version="1">MIRLDGISCVQVGDKSPIVNCLTKQMILVVHVPSNEHLYHICAPIIFSVEPFHRKVHGIGKQNGAVQCVYIHRSPLGRRSGFEESPPGQPFPEEPLGKAPLLPFFWLLFTRVLVKAICQSRLWTMANEYPLQSRMYTGLSDTNTVLEARPGYMPVSMWPDKSVERNVLRLRLRRKEEKRRPPPSMYHPWGKQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
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    <name>A0AAV4TTW9_CAEEX</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">CEXT_654451</name>
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        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
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            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011820">
        <property type="protein sequence ID" value="GIY49319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TTW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12585" checksum="579F9AF5886EDA52" modified="2024-11-27" version="1">MVTLEKFFKDVLMIILLFDTRNKTCSETVEKNNSKEELVIGDKFYEMSVMQRDIFRTFILSPPLLRRISSRVSESLKRILKLHPPKRIGDLLLFPSRHWTLKFISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U251</accession>
    <name>A0AAV4U251_CAEEX</name>
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        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_328473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
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            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
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        </lineage>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012167">
        <property type="protein sequence ID" value="GIY51832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="ZN608/ZN609"/>
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        <property type="entry name" value="Znf_C2H2_type"/>
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        <property type="entry name" value="BRAKELESS PROTEIN"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
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    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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            <begin position="626"/>
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        </source>
    </evidence>
    <sequence length="1825" mass="195973" checksum="EE3B75313C1E6511" modified="2024-11-27" version="1">MSGNWVLGDLIIDLDADIEKTNEKNGAGNTQQGIPSQHGHHHHSHHHHSHHHNNHHQNGSVSSPGSSSSAGNSSVIDSPNSSSSATTFNFLGGQTSCNNSLAVAMSNSKSSRIASNSGVGSNNAGTTSGTGIVSTSAGSNNGNNSGGSGTFEHQATVDKGLKMKIKRKTVGSKYSEAKHEIVQSDTKSATSSSHPLSENVNNVSNNNCSASGSSSSASSSDTPKSKHSSSKGRNGSHREKKEKNRDKDKNSNTRNSSSTTTPAAEVNGVLGVMSPLKISNSDTNISSPAPPSLCSNSSPLPSNNSAAASPNVSRSVTGTNIANSPVSNCPMDISQPALISLPIQTVSSSSSPPMPNLTLKLENKFAPSPISQTCSIPSVVIKPEDKPGSPPQKKIKLDIPEHVEEAECGGNIVETPEMKDISTCTTCTSVGTITEPDCLGPCEPGTSVTLEGIVWQETEGGVLVVNVTWRGKTYVGTLLDCTKHDWAPPRFCESPTSDVDSKAAKGRGKRGRGGNTSSSEINFTDTRNCVQSKLRNGKGRRTTVNSNATSSGFTVPNSPAKGENGTSGGKRKGRSTDTESNSTSESKNSKRNRTQNRSVPTPPVASPVSTTNASAESSQPSSPQWITCPEPNCSKRYKHINGLKYHKAHAHSSSDNCKMDDTTTEDSKDVTNSSDNEESMQESTSVSTSPAPSFANSVPSGEKNLLNGENASSSSSSVNGLPENDPYSLTTDLSTLASVAISDSASGQKVNNSTRPLPTNTLHSNLSQDLPIINSDGENVGSPTVLPVSVTISSTSVPLVDGLSVSSALSSGGTGLSAPVSAVTTSVIQSSNSVDNNIAPSQAVNMNIPAPHVILSQGMLGCSSTTTCTYTSPVVCHNSNSLSPSMNNLSTNVTTTFTAISSIVSTAIANPSTPLPMIDKSKIKQERPDKYKPKSPLGTSAIRPIVPAPTPLIGLSTNIPGSHPGISIGSHCVSPSLKPIQPKPTLLGDLAAVNPALDSLKKEKSKHKKKSKDKDKERDKKLPPLPLTPTKLGMSSNDECEALELTSYPSLEAVSGPLAAVPHPTLSPLISQAKPPETSMDMSLPDDTMNENIQSPAYSDISDANDTAPVLESEVPSGKEKEDKVGKTTPDASQSPATNISAYGMYPYYSQPPYLLPSVSPQSAVSGPQGPNVMEKNDLSKKDPERIKESRPWSNPSGDMRERQHLDHHELEKKQSREDGGSNVNPLTSPAPGGVPVQDYPIPQHYPYPYGYVQGYPYPVDSSSYHMHMLESDPHYKQQYKQYIDEHHRMYKEQQHHHQQQQQLQHIQQAHQQQSHHGHHHSQHQSHHQNKSHHSIIKDERDRSRESKDRSVSLDKMSSSGLINEHSSKIQHSSNPLMINKDQDVREIEMRPPSLPAQARIDAAAAAAASAPSASAVSLKEKQNENHQILKENIELKSQMDENKSKINQYEMAMLYERHKEDMRRYYMCQERVIEQQQQKMEPGIHHHTHHHQTIQSHSHMQASYSSSSLKNMKEELSGPIPMHSKSNHYGEGTRPSVVSPAKSDHIKNLHSTSSPKGNTRDRDSSLSNPKEYLNSSSRESSTSKKDGSKNSERSESSTRDEKKIDKIKTEPKVESEGQKPTMETTGPPPPPTNSYAYLHPSYLQPPPPHFTHLPFEPTHPAMYRGGINPMIVSTPHYANSPYMHPQIRYVTPGACELPVHAQPPDPIANKLHPSGPPKALDLLHQVSQQYTTTHKIHELTEHAVMSPTPTSTPSSIPSTSSNSSSGKTSTEPIVAASKVEVGGSRDASRSPPTQRHLHTHHHTHVGVGYPIYDPYGVAAQKTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3G6</accession>
    <name>A0AAV4U3G6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_195521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012229">
        <property type="protein sequence ID" value="GIY52341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3G6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11520" checksum="DEEF830875D27D3A" modified="2024-11-27" version="1">MLLMYHVIKLINYITKLQSIITLKLLFAFSFQVQITTLCVSTSLSAYVALFCLFSPQSVHHHLPPGQERAQADHEQRHLQEGTHQQHLRNIRQSGQRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U688</accession>
    <name>A0AAV4U688_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Beta-1,4-glucuronyltransferase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">I-beta-1,3-N-acetylglucosaminyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Poly-N-acetyllactosamine extension enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">CEXT_235621</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>3-O-[beta-D-Xyl-(1-&gt;4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1-&gt;3)-beta-D-GlcNAc-(1-&gt;4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-glucuronate = 3-O-[beta-D-GlcA-(1-&gt;3)-beta-D-Xyl-(1-&gt;4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1-&gt;3)-beta-D-GlcNAc-(1-&gt;4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46860"/>
            <dbReference type="Rhea" id="RHEA-COMP:15023"/>
            <dbReference type="Rhea" id="RHEA-COMP:17482"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:142405"/>
            <dbReference type="ChEBI" id="CHEBI:177336"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012338">
        <property type="protein sequence ID" value="GIY53248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U688"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043189">
        <property type="entry name" value="B4GAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46420">
        <property type="entry name" value="BETA-1,4-GLUCURONYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46420:SF1">
        <property type="entry name" value="BETA-1,4-GLUCURONYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="GIY53248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="238" mass="27646" checksum="F3C6627E667029A3" modified="2024-11-27" version="1">MTLLSRLEARKNNSLRNGDKSEWQSHQEYQEAQLKKDMTRMLETIKQSSVLDSSGEYRIINFVMRAENLGVKNNIRQDLSLVTQSTIKHLVHLESILNRWHGPVGTIQHQFSSSLSFEQSLTTRHRLPNRLCWILAKRLKIRSRVFEISDNYAHGVPYPNNLLRNVGRRNALTDFIFVIDIDMVPNDNLYSDFMDFAVTNKLFIDSHKDDKTVYVVPAFEVKEGVEVPRDKNWTVAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEU3</accession>
    <name>A0AAV4UEU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Klhdc4</name>
        <name evidence="2" type="ORF">CEXT_815141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012759">
        <property type="protein sequence ID" value="GIY56337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13415">
        <property type="entry name" value="Beta-prop_FBX42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="531" mass="59584" checksum="A98B536C92907578" modified="2024-11-27" version="1">MGKKDKKKGKGAEKTALKTEKKALNKLKKDLAAKGEGDIEKLIAESQKHIQKADYVGEELCPQPSPRSSCSLNAHPDKEELVLFGGEYFNGKKTTVYNDLYFYNIKKGQWSIMHTPVKPPPRSSHKSVVLSQSGGQLWVFGGEFSSPSRSVFHHYNDLWVFHFTEKRWEQIKAPGGPSSRSGHRMAVRRKQIVIFGGFHDSVGNQRYFNDIHVFNLDTYTWSKIEASGKIPPPRSACLFAPLTDGRILLYGGYSTEKVKKDVDKGITHTDMYYLLIDERAAPHKWKWVPAKPSGFPPSPRCGLSFAVSPNNRAYIFGGVCDDDQDENLISVFCKDLYVLELDNGRFSPINLRGKASGLMRKKRRGARDNDVKILDDDGEEEKSEERNDVDVEVAERLKEVSIKSDDIFTVTVSSSVSVASSEKSASSSSSSSNEAFAPKARMNSTLAVKNGILYLYGGTYEEGDRQYTLSDFYSLDVHKVDEWRTIVPFSISNLDWEDSSGSESEDDDDDDDEQDDDDDDESSESDDMDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UI68</accession>
    <name>A0AAV4UI68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_676841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012922">
        <property type="protein sequence ID" value="GIY57535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UI68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18426" checksum="C435FB15BD036C97" modified="2024-11-27" version="1">MLMIHGKNIGDLQTQFKTAVDTEKWMSHGVDLGYTKPDEVQHAHQFVLNLEEEIKRLQQTVNDLGLCPLTNCSRHSNAKVNNKTKRRATASDNFSVPPKRHTAKILVNDKLKEVRLENKFSNLKVDKAVAGEEQGTPTEPKMPPIMRTAATAEAKPVPKCIYPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQW1</accession>
    <name>A0AAV4UQW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Complex I-MWFE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_88966_1</name>
        <name evidence="2" type="ORF">CEXT_644371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013258">
        <property type="protein sequence ID" value="GIY59959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY59959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8401" checksum="35F8047861DE7289" modified="2024-11-27" version="1">MWYEILPTLTVFGTFLMIPCYAPWFVNMAIRGKPHVRTAMDMEDRKLTMRDERLSGHIFKMKGLEQIPDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTU4</accession>
    <name>A0AAV4UTU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_520161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013469">
        <property type="protein sequence ID" value="GIY61447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UTU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="8987" checksum="F61967C4C5649B75" modified="2024-11-27" version="1" fragment="single">EEGLTPTRSPFLAGGQTLSKDDPCRASNGEEGMAIKMHPILPPPLPTPFGRSAGSTGMLACSTTNRLLIRLQMMILSNGFITSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVR7</accession>
    <name>A0AAV4UVR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">AVEN_226286_1</name>
        <name evidence="11" type="ORF">CEXT_559242</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Early endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PMEPA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013525">
        <property type="protein sequence ID" value="GIY61808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070412">
        <property type="term" value="F:R-SMAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009968">
        <property type="term" value="P:negative regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043445">
        <property type="entry name" value="TMEPAI/LRAD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16514">
        <property type="entry name" value="LOW DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16514:SF3">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 4-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0734">Signal transduction inhibitor</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY61808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11981" checksum="B45E1841B5CE63E4" modified="2024-11-27" version="1">MPTAFHCLGRRRGRLYSQVVSAARIYMSAVQIFIIVITVLFAVGIITCVLSHYKMGARSWSDQRNRQQPSARQQPCPQQRQYTYSLTPRSISFNHLVRKCSSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVX6</accession>
    <name>A0AAV4UVX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_482381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013540">
        <property type="protein sequence ID" value="GIY61868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14056" checksum="847B29EE4CC5BB45" modified="2024-11-27" version="1">MDSYVESIGPPFLYGSRRTQSGISLLLVKKDTYNKVFVVNRPVFGALWCNKGLRFLYSYDKKLANNFDNVRDMYRSLYVVLAELLESDHKSMYTLLIGHFAFGHLCELWLLKSLFCPFVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXK6</accession>
    <name>A0AAV4UXK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_734311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013618">
        <property type="protein sequence ID" value="GIY62435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20862" checksum="4B65D860368BE589" modified="2024-11-27" version="1">MLSFHTFDSARLEKKKGEMEPIAASSRLIRNSIRFVAQTADCFSCEAHEPPVAREKQESVCLGGQKMEKNLMANLIDERKFIVKPDNKQHYCAPVDNKSNLKSFLASKMLLSSAKMNCQNFGSDLRPSLCRSFRINNRDDTANQKRSSDRCSPFRRFDSARLKKERRNGTHSSIQSFDKKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCH4</accession>
    <name>A0AAV4VCH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_22891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014230">
        <property type="protein sequence ID" value="GIY67354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15599" checksum="C406892BF73E5544" modified="2024-11-27" version="1">MINILFHCSPLWKISLFRWVIQTWTRAPLPHQKKKREKKQFVFGFRHALFGLLRTSYQFHIIIKQKKLHSPTLNFSKQLPVTRSLKSNGWGITLGRINRGGKQADACFQGRSKDRTPTPQSGNRCAISDINLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VD32</accession>
    <name>A0AAV4VD32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_202901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014315">
        <property type="protein sequence ID" value="GIY68037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VD32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="524" mass="59350" checksum="A4CA5F3C8E6B028F" modified="2024-11-27" version="1">MDNLSLLKNYSFKQLSSESIFQEKNYTSSSDDKTFYTSPKLFSSDTELSYLSSSTDLLTNKYHSTNKKFKAEHRLKRKSLIADNALGKSIADPECNFSFTASVRLLLPLKKSVVKKEIGKPADKKKERKLYDSNSFNKGTNFSFSSKGDSFWDGIQPRWSSIYEHSLVYEKITKGKLKPIFYEHIANKNQSIREQANNESSIVNDKCSLLPGSNSRLSNKGRESYDHDQTLVIKKSDEKNAAYVVFKQDEKENQTSNRQINLVNSDSCNNTCKISKTNEFVCKDTDTIYLEDNSSKIELKKFEDKIASEIVDDTFNLKDNVTKSINVEDEFKNIKDSQVSSKDASDSKKFVSVNLTEGKLFYNENNIYANTSIQLDSGEIKLVGSEVCEKLKSSDAEIISNDKKRNFLNIFSSSNVSCANLEANSKEIAENTNSKENLEDIVFKAEKKIPLRDENNEDRNLKHFGESFQWYAHSETSKGNEVFYSSPAISNFSEEKIPAAAEAFNSTIQKTSFLASTPKIIPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEL1</accession>
    <name>A0AAV4VEL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GBF1</name>
        <name evidence="2" type="ORF">CEXT_694231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014364">
        <property type="protein sequence ID" value="GIY68324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="426" mass="46932" checksum="5C45C2811A1856DA" modified="2024-11-27" version="1">MPSPDNGIYIIVGEMNMVMTSMKKASRWSSNIHQEDEQDILLKNFSDLKELLNQVNSINDLEPITYLKPFLDVIRAENTTGPVTGLGLSAVSKFLSYGLIDAKQPTAPLAAENIADAVTHARFMGTDSSSDEVVLMKILHVLRLLFINTLGVLLTNESVCEIMQSCFRFCFETRLSELLRRSAEHALMDMVQLLFSCLPQFTEDSRCAYMKKLKMRSGALDAGRSSRRKRSPRSRKQRSQMTEINEVDPSKSQTNNLASSPSNSPVLTHKDISPLEGNSDSVESCQEALQSIETNNIIENVNISAPESCNSSVSEKENINESINDLNANGSDLNQNEEASESQPVQPYSVDIACDSNDNTSVSMISILPNENEVCAQGPEDTSLADHGEPDYVNPRGVRFTPHQQPKEGICSLLTIGVQYLDGSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VI80</accession>
    <name>A0AAV4VI80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_379971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014599">
        <property type="protein sequence ID" value="GIY69851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VI80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="9129" checksum="C078D6A528208FE8" modified="2024-11-27" version="1">MIGRFSRWSEAFSIETIGRDSRKKSDFKLDIPFRSLENLLPRSQMSCIQISFRDYKYYTWHDTICNEYSSSLQSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLY3</accession>
    <name>A0AAV4VLY3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_789171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014725">
        <property type="protein sequence ID" value="GIY70814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040309">
        <property type="entry name" value="Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="457"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="515"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="588"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="744"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="916"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="457"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="590"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="744"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="916"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="936"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY70814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="973" mass="108515" checksum="4D07FF3C94360462" modified="2024-11-27" version="1" fragment="single">AYYQPRLLNFSHVVKRALKLYSFLRDIAFFQKKVPTFAMAEKQEKSPLSSILIDYASTSKSVEDPNAPVLSIEKAMQIPDSGEKLESAENPSASISSIDHESTSIELIEHSNAPDPSTEKKVPTFAMAEKQEKSPLSSILIDYASTSKSVEDSNAPVLSIEKALQIPDSGEKLESAENPSASISSIDHESTSIELIEHSNAPDPSTEKAMEIPDSTLAEKPSASISSIHKLTENLNGPNLSTEKAMEIPDVVMAEELERFPSGSISSIDCESTFEAVEQPNVPYLNTEKAGNVPAHMNYRESDSEDSLSDSDSFMKEMRKNAFKPTEKLPPLVTKEFSVLEYDLPPVKDLHIVPEKELCKIGVILSIVENLVVVDTYNDAPALNAETVLFLSADKPLGKIFEVWGRVTHPVYSVRFNSAEHIKEKDIIIGEDVFYSPEETELTNYVMVSELLKEKGSDASWKDNQEPPEECREYSDDEKERNANKKRKSKKRHNIGNPLAILFCEDQVKSFGQKRFAPSRENISQRNNFNSSDRYSRTRHMNRQNESASLNSVSSSTHRNIVQDSMSEIQPWTQASAVLEYVTNLAKCENSSDGKPPETFLKKENHKSTSFRSPMILNQSNSQISAIQRSSRDSIPGFPFFELCQSRPPPTSSFGPLQQNFMPSNDNFGCMHPNFRPPNYTFGFNPNLRPPNYTFESNPNLGVLNHTVGPTHLNPAIPNVVGSVQTRFSNIQHHQQMDQMNYNQQASPYNNRSPQPLSGPFHSLSSQTPQSYRPVHTNPAPPPTDSQNFVSTQGFILPPRPPLVSDQNQTFQYRSESVNMHPLYSSALHTTAAASVTSPSPNHMTFQQQFPVQPRSQVPVSFPPMLNNIPNQSPHTTAASSVTSPSPNHMTFQQQFPVQLRPPAPILFPPMLNNFPNQSPHTTAASSVTSPPPNHMTFQQQFPVQPRSQAPISLPPMRNNIPNLSPWESFPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTX5</accession>
    <name>A0AAV4VTX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015052">
        <property type="protein sequence ID" value="GIY73261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9597" checksum="46385CCAEB7473C4" modified="2024-11-27" version="1">MRVDVSLYIISSYSELKLAMTCTEFNTTTKDFIRICLHKVGFIKPENSIYGHCRVRAQGLDIGGGQGIGHWWRTRDWTLDILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VW24</accession>
    <name>A0AAV4VW24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_301881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015223">
        <property type="protein sequence ID" value="GIY74486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VW24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14669" checksum="F7FE5E10AB5EF5BC" modified="2024-11-27" version="1">MRAGTPLLDPFSSPSPSKRKERKKAGREETLLYHAIGNCNDQYVHESHSVTVTVLYPLTNFVNSRRRKRLQKLQPLPPSPKRKSIDIIELRRFFYNRKRNALCTPFLFFLVLFCGRCSEESSEVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VXL5</accession>
    <name>A0AAV4VXL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IRF tryptophan pentad repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_79507_1</name>
        <name evidence="1" type="ORF">CEXT_94181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015153">
        <property type="protein sequence ID" value="GIY74010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VXL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="418" mass="48342" checksum="2B09B336C3498B4B" modified="2024-11-27" version="1">MRQFLRTSDNPFPFTEFSSWKAGVREIPFLHLANKHAKFSQYETCAILEGSEEYLENIKEKFIKMGRNGSKLITFFLDGLKTNKYQNLKFEDSSRLIFSLYLPFKTNKLDKKNEDVLKDWYHINNKKYFYSTNYTEAKQAMMASLRKSDYVEQIAIGDNKMTFRILTPKEIKGKGKNVNHFFFFQKKERKLILKKEKQNKSVALPGYGSNMNNPYHALSPYNATGSINENNGLLQAIEHDHYFGFSPFERLPSNGNVSEASSYENAEVQDGHTKFVARESGNIETNANLLEEVCNQEHNIVSLDDLDKIPSNDLVKCGETFDMEEFMSIYIPDGDIHDFSKKPENRFLCKKLEYLVKTPILICEYLDSQVSEVDFTSGQFKIICDEAVLKEILDKNLKISDYQLVNGHMLVILEPDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W1J5</accession>
    <name>A0AAV4W1J5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_812441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015422">
        <property type="protein sequence ID" value="GIY75965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W1J5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8733" checksum="66964834EDE72DD0" modified="2024-11-27" version="1">MLPNWPVGGHRFAEVTPVKGYAEMKRSSSTIKLDQNASSAVSRCGGQLYDGQAPYSHEKSENERHDRIIENEVRRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W814</accession>
    <name>A0AAV4W814_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphotransferase subunits alpha/beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GNPTAB</name>
        <name evidence="14" type="ORF">CEXT_390371</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Endomembrane system</location>
            <topology evidence="9">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the stealth family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015701">
        <property type="protein sequence ID" value="GIY77974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W814"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003976">
        <property type="term" value="F:UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046835">
        <property type="term" value="P:carbohydrate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016256">
        <property type="term" value="P:N-glycan processing to lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21600">
        <property type="entry name" value="RRM2_GNPTAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041536">
        <property type="entry name" value="GNPTAB_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035993">
        <property type="entry name" value="Notch-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000800">
        <property type="entry name" value="Notch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047141">
        <property type="entry name" value="Stealth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031358">
        <property type="entry name" value="Stealth_CR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021520">
        <property type="entry name" value="Stealth_CR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031357">
        <property type="entry name" value="Stealth_CR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031356">
        <property type="entry name" value="Stealth_CR4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045:SF0">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18440">
        <property type="entry name" value="GlcNAc-1_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00066">
        <property type="entry name" value="Notch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17101">
        <property type="entry name" value="Stealth_CR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11380">
        <property type="entry name" value="Stealth_CR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17102">
        <property type="entry name" value="Stealth_CR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17103">
        <property type="entry name" value="Stealth_CR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00004">
        <property type="entry name" value="NL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90193">
        <property type="entry name" value="Notch domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50258">
        <property type="entry name" value="LNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1006"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="domain" description="LNR" evidence="13">
        <location>
            <begin position="388"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="803"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY77974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1049" mass="120705" checksum="B88FAD8C4FD8B710" modified="2024-11-27" version="1">MFGKLLCKLLQRKTYDVLAKKHTLLLLFIGFIILFVSALRLVNPYSNNIGAKNFKNTLCQYAPIDVVYTWVNGSDPAFLKELSKAKEEYGFLNSRMNCSFSNCIKSHMVLVKPQLPSSLILSDLEETDVVFQHLSGTFVIASPHKSFENITVLIFPDLSSAEQVLSKKIISLEGQNYTLSTAYITDNWGSQSTVLLNNAVFLTQLPYGYSVDNILEKLLPSIRTTISQVFIYEEKSLAVLTLNDPEALDTILKLTNITFENKVASVASAYLVIELPTELRYSLRSLEKHAPWVQHIYIITNGQIPYWLNLDDPSVTIVTHEEIFPNKSHLPTFSSPAIECHLHRIPNLSQKFIYLNDDVMFGKDVWPEDFFTHTKGHRVYLSWPVPNCADNCPHAWIRDGYCDKPCNNSQCQWDGGDCTADNPMLPHQALGIQQEGGVTSYFHIRPFKNYCNVECADTWLADRYCDKACNIRECGFDAGDCGLDNFEEMPQIILSPNQSHYYLPDGEFVGFFNMTDFLKANYTISGGEFRKEQFQRKITLHVFTKFLQISTTIPTAESQNETKTIITEEPYTFKAFAEEKRFPKFNPVVSSELDFKFQNINITASRLPENLTIEILKIKHLRDTGLLSQEGYLRKKSNIIATYFVTFNETNDNETMLVTEREEADAKKVWENLNKIVDPNIWKSQETKLSIKNSQNLPKGPDTKPTSSVNEKSTYLTFNPTQRHLLDTFGDSLRHVNKLYNEAFGYESRKVPSHIAHFVDKDVMSRLTETFNDAFAVTSSHKIRSSNDMQFAFSYYYFLMNEMETLEVEEIFNSFDTDNSGTWSDREIRTVLARLYDIPLDFSSVAGFEQLIVNCSQSATSPLVQPSVPHGERYYDSKLPVVSLSLVKSCPAVSSLLLKHLGIQKRNQFQEMGEEEVAFKMIHNNLSQVLGQIDDLRKRPKKFVCLNDNMNHGTQEAELIRTVIQDFYESLFPVKSRFELSPEYRNKFLYVHELREWRKTRDKIRIVAYATLGILILFTLLSFWKSEIRRTERYPRLRAIHNRRNSHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WL75</accession>
    <name>A0AAV4WL75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_462401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016414">
        <property type="protein sequence ID" value="GIY83646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WL75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15577" checksum="53419DA038466184" modified="2024-11-27" version="1">MDIRPFRPFRNASPSSALLTAPLTACMGEKRIGFSFTSIAIKSDFIHSDSYPSRKSLIIHPVHLWLMTSMDIRPFRPSRIASPVVALLTAPLTVWMGEKESVFLLHQSPLKAILFIAICIRPRKGLIIHPVDRRRMNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMG8</accession>
    <name>A0AAV4WMG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_605851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016345">
        <property type="protein sequence ID" value="GIY83146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17402" checksum="F38453BC4E91E7FB" modified="2024-11-27" version="1">MLQSCTILTIVTKTNGASGKPANTPSHLSTVHLGRRMLVYRIPEKVFRKVLGVSKQWPLQWDDYRRIVTMGDIVGCPPHARSHVQKKCLPVGPLPGRPPARMVGPRPMEHPQGLLSTALIRFSELPNEFISSAIFWVQRYFISKKRRFLFLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRP0</accession>
    <name>A0AAV4WRP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 4V2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Cyp4v2</name>
        <name evidence="9" type="ORF">CEXT_760001</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016666">
        <property type="protein sequence ID" value="GIY85570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY85570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="485" mass="56154" checksum="D0057D73A74D8206" modified="2024-11-27" version="1">MLLEIVACVSIVVIALLAKLSWWRQQCNRLIPNNQPSFFNPLGEVLEYDGIMAAFVKWTNKLRKYPLFCAWLTYMPFVLIHKSEAVKELLQVQKHIQKSWFYYFTQAVVGKGLFTGTPRFSRTNNSFIILHVTIKVIVASGRTGGSCSPPCFQSNMLKGYLTVFNEHSLKFVKHLMKETEKEFTSIEEPISLCALDILCECIMGVKMGEFENERKQYVESLHRTLDLVMARILKFWQTIIDERKRRYLNGEKADDSSRYKSLLEVLLKLHIEDQALDEKGVRQEVDTFIIAGHDTQLQPLSNRSLSVDDLSDLKYLDCVLKECSRLYPSVPQFGRQISEETKICGYTIPKGASANVMTYFLHRDEDVFLIQRNLTRKEDQQELQKKRKTVAQSLNMTYRIISISISMVTDALECIKFSVHALKLFFSAGRFFGEMEVKTMVCHTLRNFTLHSLDSRDKVLPVMNVTLQSSLPIRIRFRPRHNNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WV59</accession>
    <name>A0AAV4WV59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_745081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016749">
        <property type="protein sequence ID" value="GIY86154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WV59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11119" checksum="25682C24812AA814" modified="2024-11-27" version="1">MSFFLVGAPKSKKSIELLNIDFSYRFKVKAEKLRRRLGPAQCFNCLQFFHHSSPVHVTQCAEMRMRPKSSEYPKPPGGQLASGRSFGIPGFHFVSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVY6</accession>
    <name>A0AAV4WVY6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rab-like protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_421572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016862">
        <property type="protein sequence ID" value="GIY86922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040385">
        <property type="entry name" value="RABL6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14932:SF1">
        <property type="entry name" value="RAB-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14932">
        <property type="entry name" value="RAS GTPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="654" mass="72958" checksum="92EB5B1B73AFC013" modified="2024-11-27" version="1">MFNALKKLVSSHDASSKGLPPPGVQAMGLSLQRKFAKGVQYNMKIIIKGDRNVGKSCLFSRLQGKKFIEEYLPTEEIQVASIQWNYKATDDVVKVEVWDVVDKGKKRKKIDGLKLDNKTSEVPEEAALDAEFIDVYKGTNGVILVLDITKQWTFAYVQKELPLIPNHIPVLVLANHRDMGHHRTVTEDQVRPNDSAQIRYAEGSMRNGFGLKYLHKFFNLPFLQLQRETLLKQLEINNSEIQATVEELDCLSESEEQNYDVFLDHLTNRRRQVAEQLSHVPTSSSIESVNAFSINQTNGTAEQSPVTPSFVPQQHITPKSISMPANLSQSVTENSCAPVVIAPLVAAVPSPEPPKQESGFISRFFNKSSSPKNSSQEKTKNENVVKPEKINNENVSSVDDFVPDDADQTFNSFLEDSPKNTASENVANVPEGESESEDDTVNPMVAGFQDELDPEDVVVVSMNDNILHDIKNVPSDHSSEDEKTNTLKLTENIGDTPASVEPTVLSEKEETSAEIQSPTGNVSMLNLEAEDLNILETMYDYKRKTSSETPSVPSRSSPSATPEGSEAVSEDSSTTKTRKHKHKSKNKEESKSHRKSHKHKKHKEKDDVTNKKETAQKKKHREAGDLDSSSDVDKLEEFLGNNESKVPSPQYEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXS1</accession>
    <name>A0AAV4WXS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_490141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016887">
        <property type="protein sequence ID" value="GIY87103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9933" checksum="9ED3BCCF9A63EE6A" modified="2024-11-27" version="1">MLMGNLNKPDSINIASMMDGHIKAPMNDADGEFELMCKLFSPREELYIFFFSPDSINIARRPMCVFIRSSASMMDGHIKAPMNDAWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5G4</accession>
    <name>A0AAV4X5G4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Orct</name>
        <name evidence="7" type="ORF">CEXT_471791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017268">
        <property type="protein sequence ID" value="GIY89893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5G4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY89893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="500" mass="56721" checksum="BA29F9E0226D849C" modified="2024-11-27" version="1">MAIVCCFPDSSHNMVMSFYAPNLDHWCSRPADVNVSVEEWKTIALPPDDQSCSRYIFTNFSHIREERFKNISINRRTTPCTSWEYDDSVYKSTVLSQFNLVCEREWLTSMSKSVFIGGYFLSATLFGYMADKFGRRPIIVLCNVVALFSAIICTFSTSFLMFAICRFFVAAGVTGVDNIAFVLLMEVISPKFRSAYGIGVNIGWITGYLCIPLIAWLLRDWILIQIVITLPCTFLLFSWWLLTESPRWLLANGKIDEAVVILSKIAKRNGSNITDVKLKEQVSKTHKSHEDEKVNINILQLLKSGLWQKTIIVWYLWSVNAFMYYGISYNTNELAGDPFVNFAVYGAVEIPAYIVTPFLIQLKGRKYPLAFSLTVAGISCLMLYPLPKDPWWIRPSDWGLNDFPNHTEDRWIGVAQVNGRIGAALAPFVRELGRASHPIVPQIFFGILAASGGVLALLLPETRNRRVPDTVKEASKISRKSTPKKKTDIYIELTGFKERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBD1</accession>
    <name>A0AAV4XBD1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LARS2</name>
        <name evidence="10" type="ORF">CEXT_648261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01000066">
        <property type="protein sequence ID" value="GIY91899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000003">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="9">
        <location>
            <begin position="3"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="9">
        <location>
            <begin position="303"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY91899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="400" mass="46158" checksum="BED26047742EF9F7" modified="2024-11-27" version="1">MFPYPSGNLHMGHVRVYTISDALTRFFRMNDKQVIHPIGWDAFGLPAENAAIERNVHPFEWTMNNIQTMKKQLEDFNICFDWDKELTTCDPSYYKWTQHIFLLMFEHGLAYKKQALVNWDPVDQTVLADEQVDENGCSWRSGCKVEKRLLSQWFLRTSEFSKDLYEGLNDPSLIEWRDVTKIQQHWIGEPDGFIFHLDVCHKNEVLPKALTVWTNTPELFYGATFIGISPNNHFNASEYGCGSKNEDHKLNITVKNPFTDKYIPVYVSQNLDYSSATDSCLVLLICLINSGELTGTDRQNAREKIIVKANKEGIKFYQASKKLRDWLISRQRYWGTPIPIINCPSCKAVPVNKEDLPVLLPKISDFTGKSSSLKNCDDWINVPCPKYVCILSKKQSNIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XES3</accession>
    <name>A0AAV4XES3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransf_25 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_118310_1</name>
        <name evidence="1" type="ORF">CEXT_717471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000231">
        <property type="protein sequence ID" value="GIY93084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XES3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="430" mass="49868" checksum="2DBEF9C11E13E1B9" modified="2024-11-27" version="1">MIAEEYNVRYILLLKLKSYPQWKDLSGEVVMDIGCGDGSESTKCILQLFPRVEKILAIDKHRRVIAAAKRENAHPKIEYHAANIAKILCPKKLTLMTWYNKISKIISFHCFEFVKLKAAFQNVFFLLKPGGEGVIVLMTSNAFRDAYDEMLGNRMWSRHLKNRKGPSAGFANYVTHFECAALAQEVGLNVRFCQARENTACFQNDQEIKGMFPRHCLVSMFPRHLFGVYVSKTFVWCLCFQDICLASMFPRHLFGVYVSKTFVWRLCFQDICLASMFPRHLLGVYVSKTFAWRLRFQDICLASTFPRHLLGVYVSKTFAWRLRFQDICLASTFPRHLLGVYVSKTFAWCLCFQDICLVSMFPRHLLGVYVSKTFAWCLCFQDICLVSMFPRHLLGVYVSKTFVWCPVCNIYKNVLQFSVWRGCLSMVYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG34</accession>
    <name>A0AAV4XG34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_338751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000281">
        <property type="protein sequence ID" value="GIY93579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="8106" checksum="44218F27C2E6E900" modified="2024-11-27" version="1">MIPAPGADNVRWWNDAEPVWITAERTTKDPPLYWWGWMRSRNYGWPPTICERQFYDGPPIKKWQQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGG7</accession>
    <name>A0AAV4XGG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_285671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000297">
        <property type="protein sequence ID" value="GIY93744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11646" checksum="63F1DB46D39DC87D" modified="2024-11-27" version="1">MSLQGNNARRHYWAGDYGWVIPGSLQASSPPDCQPSLTPATALLNEDSCHFHRNLKANRRAFEKTTGWLRVAACRHTTGHTAQCMVNYGSLFLAPDSKEMKTLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJH4</accession>
    <name>A0AAV4XJH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_681891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000489">
        <property type="protein sequence ID" value="GIY95232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12896" checksum="5548FD5D2F37C4A3" modified="2024-11-27" version="1">MEEVIPGSCGCSILEIVKENGNDEAIFGKTTKIQALTFIQILSVLHYGKESEWLAEDTHGFRKAKNSRHLTDDARSRSSAEVSDRSDINSGLMGACFVPPQKREKRSDLDTVQEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN08</accession>
    <name>A0AAV4XN08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_240431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000484">
        <property type="protein sequence ID" value="GIY95133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7502" checksum="BBEFFB602D855314" modified="2024-11-27" version="1">MCYNRVSHSHSRPDKLTVGGNHGYTLLDVAVLPEGGRYALSKSFCVDFPHGRNNGNDASIVWTELEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPQ9</accession>
    <name>A0AAV4XPQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_767511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017959">
        <property type="protein sequence ID" value="GIY95764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13060" checksum="09AC6FECE7E8E29C" modified="2024-11-27" version="1">MQFSKAYMYVIGTNEPDDTYKFGEFCTTVNINGIADCSLLLGTSVQLCRNLNRFVYHFIGRIRPSTRCIMKVLWLRTKSSGSQLGKLSRFRIPYVPCVNVMVHNPLFKVAKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUG8</accession>
    <name>A0AAV4XUG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_497661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000788">
        <property type="protein sequence ID" value="GIY97504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11951" checksum="47275D4AFD8C73C2" modified="2024-11-27" version="1">MLGMEHWLGMEPSHLWPGNGRGSQLTPAWPGLTDSGDQCRREHQLAPRRLLIIIASVSGRTAYISITCFSCSELNITDGGCKCQHTQDKESHGLNQKHCLIKNAKPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ67</accession>
    <name>A0AAV4XZ67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001123">
        <property type="protein sequence ID" value="GIZ00128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10504" checksum="84BF8FF54B278E71" modified="2024-11-27" version="1">MLSHSFTLSRCRTHHYVYYHHQGLRSASLSYSQPLTIPFNKCKSRGGHSYQHSAKSLTHGNYSFGAETGRLSPFPTCIFNRHRRGFVSRVGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZH5</accession>
    <name>A0AAV4XZH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_29461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018387">
        <property type="protein sequence ID" value="GIY99135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY99135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11622" checksum="6B6F42A572710135" modified="2024-11-27" version="1">MPDSWLTVATYATATPADTEADVALYVGVFVAVAVFVVVVIAMVMLVRRIKGRDPCMYRGAGTELLSYALGSGKNCSRGRKKEKDTKENPPRRRKMAPLFYCPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0U7</accession>
    <name>A0AAV4Y0U7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 4g1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Cyp4g1</name>
        <name evidence="10" type="ORF">CEXT_216361</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018604">
        <property type="protein sequence ID" value="GIZ00942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0U7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF194">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIZ00942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17744" checksum="C1FA8732E1A557F1" modified="2024-11-27" version="1">MRGARNHVMIYHALTSDLEESNRLYPPAPIIARKISKEISICGYTIPKRAQVLVSPFLVHRDGDVFPDPEKFDPERFLLENSAHIPDCGYIPFAAGPRNCIGRVFGEMEVKVLVCHILRNFSLHSGLEGPSASTHENHSRVVSTRPHQVSKQTTVNDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y632</accession>
    <name>A0AAV4Y632_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular matrix protein FRAS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FRAS1</name>
        <name evidence="1" type="ORF">CEXT_155241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018846">
        <property type="protein sequence ID" value="GIZ02712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y632"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24413" checksum="C01BDE3B74CAFC7B" modified="2024-11-27" version="1">MFHQQNFENTIKNEIMSTKRHFLKEKRYMAEYFGAPKQGLESAYRLNINEVIICAGKNGVTPVYDPTGKIYGKGPQYGCLLSNNNLKYKFILLDKHDPDVVTREIQGKPFNARFIEDVPPFCKFICTTIILGIVILRSKRAHIEEMLTVSRVTRNSYAFRTFSETPSISFQNEICEIKCKQKLKKKEMYKVKVYTPKNELYAIDNSSGTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6C8</accession>
    <name>A0AAV4Y6C8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001386">
        <property type="protein sequence ID" value="GIZ02015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6C8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20859" checksum="CA964389D5A157A3" modified="2024-11-27" version="1">MWVYSRPKGKTAFCFHRIPISLQFVEGVEMDRKSWLHVWVPFEGINLLNKKKKKGRRKKEPRGKKEQKEGNLISVTRNCRDESIGLNSGFIRARKGRPLSAFIEFQSRCSSRGRCGNGSESPGSTFGCLSRVSIFECNLKEIALFHIQILTVHFGVTVMESGDLKIYICIYIELFSIVVKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8A5</accession>
    <name>A0AAV4Y8A5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_471961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001559">
        <property type="protein sequence ID" value="GIZ03154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8A5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9212" checksum="C039D9803B9DCC74" modified="2024-11-27" version="1">MNIYSLYVKSPTPNTDTLSRRKQYTREEGLRREVRGRTSHLYSFPSWLRGPLGCQKIRGARPSVAPRLRMQREKDLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBS0</accession>
    <name>A0AAV4YBS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001668">
        <property type="protein sequence ID" value="GIZ03914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17155" checksum="B812C83600D478A8" modified="2024-11-27" version="1">MNVLNNFALVLFDDDYSLLASKKLVKLPIYFHSTTALPYLSAPKIKKRKSKGANLHPATMLLNAETYAKANTETDLLYSTFKDKNITFPTQKPVKLPTYLASTSVVPYLYTDKRKEVDKKVTYFEPSTTLINTIIHTKAKCSYRAITYQCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M550</accession>
    <name>A0AAV4M550_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP synthase F0 subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_112283_1</name>
        <name evidence="2" type="ORF">CEXT_18201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019315">
        <property type="protein sequence ID" value="GIX66491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M550"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027197">
        <property type="entry name" value="SLC43A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20765:SF1">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20765">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX66491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9517" checksum="CAEFEA4C74131E00" modified="2024-11-27" version="1">MPRSKKYFLLFWGLLETWVFSGSILGWSALHYMLKQEGVYGHLCTTVQDVPSTNSTASSLLAPLLNPVDEIEETIVPSVQVSFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7Z2</accession>
    <name>A0AAV4M7Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_194941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001917">
        <property type="protein sequence ID" value="GIX67998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13185" checksum="5B401702D312BB8B" modified="2024-11-27" version="1">MKELHDQFRASLNCEDGSPPHLTPSFEISSQKASEKGEERRLKDLTPSKRLGDHRLLASLNCEDGSPPTFNPVVRNLQPKGLEKGGERRLKDLTPSKRLGDHRLLLTETPKRAFCLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDD3</accession>
    <name>A0AAV4MDD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019678">
        <property type="protein sequence ID" value="GIX70447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12875" checksum="04C3A433A42FC2F2" modified="2024-11-27" version="1">MASNLSWRRQNLFIKKSLPPPLYFRLSSKLPAFEKYLSGREVIEKDESLQIMGYINVDLNNKPGDKFLPIHQFKSDGKCQSFPVDDRPEISISSFHFEAFMMMSNHSVLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIC8</accession>
    <name>A0AAV4MIC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_785611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002280">
        <property type="protein sequence ID" value="GIX72118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9723" checksum="9B55999421EA249C" modified="2024-11-27" version="1">MKETQRNFWSEHKDLRVAERTQLPQSRRGMKAPFVTTQERRGCASEIAVNTPKSPTWLFQTTQSIFTVPHLSGRSPNPITAPFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMN5</accession>
    <name>A0AAV4MMN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_422871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019969">
        <property type="protein sequence ID" value="GIX73618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11327" checksum="4E2FCA7B30494C04" modified="2024-11-27" version="1">MAREEEFVTKWPMMSADIVRCVNLHNWTLPAESFWGLLDQQSLPCMRLQNATFSLRSFGLTSTMGNARELHGRILIPHRKKDCNIRSSIYGCLDTIAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQ69</accession>
    <name>A0AAV4MQ69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_647091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002467">
        <property type="protein sequence ID" value="GIX74040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQ69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8657" checksum="EAD40E48E605F0C8" modified="2024-11-27" version="1">MIAIQKILILPIIYLHFERFHPLRARGSSAGKEVERETNFFERSQKKRMKVYWKRHLGNTLTQLPIPLYLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTJ0</accession>
    <name>A0AAV4MTJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_480881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020143">
        <property type="protein sequence ID" value="GIX75184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF5">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="22035" checksum="A203CCAA5A17850D" modified="2024-11-27" version="1">MRQALQSSSLLKGVGTWHSVAHCYIHPSIQPSIRPPIHPSVHLSIYPSIRLSFRPYVNLSVRLSIHPSVRSFHPSIDPSIHSVHPSIHPSIRPSIHPSIHHRSVHSSIPSISPSVHPSIHPSVSHIYPYPSVHIYIYSVHNKRSRIQNIIGKLMRVVSLFTSFDVGVLQDEIDLPWWDKLTRIQSICKIQMKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWI9</accession>
    <name>A0AAV4MWI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020229">
        <property type="protein sequence ID" value="GIX76113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10199" checksum="5A2254FDCF2ADE9B" modified="2024-11-27" version="1">MFCHEGPRQAYTQRDRKPKGGFVVHAKILLPSFRAPSLFIACSKWFKPTAVRHSSVSSGGLEVKMLLQFSIPLRNSGIGDILDPRKKIHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3T6</accession>
    <name>A0AAV4N3T6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_517191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002813">
        <property type="protein sequence ID" value="GIX78044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3T6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12389" checksum="926FA09251AD8298" modified="2024-11-27" version="1">MKKVASGSQFNSKVIKLGAFNKLNNSSLNWFKLFQRQLRALNQDLVKIFTRRLRFTTQLILLSQIWLFGVDIDQLRDSSNKTTRHAPGQDKFLGASFTPLVTFTLKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9I5</accession>
    <name>A0AAV4N9I5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_702831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020571">
        <property type="protein sequence ID" value="GIX80129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9I5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="199" mass="23046" checksum="52416125D153175C" modified="2024-11-27" version="1">MNAIYQMFVGNVLTTTKPKTAQVKKMRCINCVRHNECIPNPSEHSNEKDHYAFQNSCPVYQNHLQLKREEDISALETKKQMKQQKPVTPTQEHQQQICQTITDNIKDQMQNMIKENEITKTKALQEKLCENITNNLKAQIEKIFKEQITIQLETTTVNETPTKQETAQTPSQQTGWSTSRKKNHITDPNRGVKCNAIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIM2</accession>
    <name>A0AAV4NIM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_514761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020896">
        <property type="protein sequence ID" value="GIX83703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12414" checksum="032F1E04D821965A" modified="2024-11-27" version="1">MAFPRERVEMASGRRKIVKATVLKKLFRKSNKCLKPAVVGIEKKKWMVFPQGESLDGVWSWENRNCDRFEKLLGNQRVTFEQKVLNNLKKLSPVLQKETCHSGVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKG7</accession>
    <name>A0AAV4NKG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein-lysine N-methyltransferase EEF2KMT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EEF2KMT</name>
        <name evidence="4" type="ORF">CEXT_81961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021031">
        <property type="protein sequence ID" value="GIX85183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029426">
        <property type="entry name" value="FAM86_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14904">
        <property type="entry name" value="FAM86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAM86 N-terminal" evidence="3">
        <location>
            <begin position="35"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX85183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="302" mass="34426" checksum="122D46B008D5EBC7" modified="2024-11-27" version="1">MQYTLELIEKIYLSVTKNKKILLSCFKNEALELLKTDVQERILEVTIQNPLCISYPPPLSFQKFFLRCLYDCVENFGSECSDGLANAYADILAMQDTDRIGYHSYKIDESRTITLQEDSHFVTKSTTGLQTWEAAKYLSEWCIRNTSTLEKKTVLELGSGIGLLGIIVLKYSKPEKYIFTDKSWEVLKLLSSNIKINISNSENSAIQQKQLMWADINDKEAATLSPDIILGTGSLIQALKKLMFKKSSCAYIASTIRNPETNNKFLEQLGSSGLSYEILKNHEKSLFIYDESSVFMLYKIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKJ8</accession>
    <name>A0AAV4NKJ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_561931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003489">
        <property type="protein sequence ID" value="GIX85213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043808703" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX85213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11034" checksum="44D244D9C3027122" modified="2024-11-27" version="1">MLILRQLMFVIFVCERSAALMVEREVGGWATPLRNLFPASSRTGDTPSETGFSPYKARKREGKVASQPSRRVPSYVPTTRVTKPQQNPKNSPRFPVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTY8</accession>
    <name>A0AAV4NTY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tumor protein p63-regulated gene 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Tprg1</name>
        <name evidence="1" type="ORF">CEXT_763931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021154">
        <property type="protein sequence ID" value="GIX86577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040242">
        <property type="entry name" value="TPRG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31108:SF1">
        <property type="entry name" value="HSAC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31108">
        <property type="entry name" value="TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13396" checksum="45719DA8A04C8C8E" modified="2024-11-27" version="1">MPARNQLGIQCSWSSSEQIPVLKRWNPWSREIPWVTYTSHPLFKMDTAEKTNYNIEDFSKKLVATVCGESANEIPAATPSSGTCRVLYQPIIIESYAGLAAALHNANELGFFKSRGKVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUV6</accession>
    <name>A0AAV4NUV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_710201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003782">
        <property type="protein sequence ID" value="GIX88569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8718" checksum="4760C5DACAB1EFAC" modified="2024-11-27" version="1">MDIPVPRHRVWWREQTKSRSTDPRRHVGSDLKNHSTFCATWVTGCGCPLRGGVVRDPKPSSSEMTLMKKISTITYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4K9</accession>
    <name>A0AAV4P4K9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_670231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021660">
        <property type="protein sequence ID" value="GIX92140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4K9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13227" checksum="25791D2F73ACAAB8" modified="2024-11-27" version="1">MVKGLVNRPYKELNLSLFNGSLRLSMIGERKANLSNKNHIEAPLTVLKNICYFYHAFIDGHSSENTLITLKCYHSFEQTLMTHLCLIRRSPLYFINSVERLYSLRIYHALFCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P550</accession>
    <name>A0AAV4P550_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003928">
        <property type="protein sequence ID" value="GIX90282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P550"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10503" checksum="9E7CB37D3F740564" modified="2024-11-27" version="1">MATSGAIQFQLGLVETFLFGLMYEAHLDYIVFSLETEILEILGFLSDARAIGDSFVMQEDNVRSYRARFRNSTYIALRCNCTKDSVSMELGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6I8</accession>
    <name>A0AAV4P6I8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_117021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021598">
        <property type="protein sequence ID" value="GIX91623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9068" checksum="B2D202B367F459BC" modified="2024-11-27" version="1">MNSEDYQAIKNWNPDSAVFGHKNVLENRETSAPESGYKIISNSNHALTYCVATATKSPCKFLLFAFISIHSIHFGLSLSCSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6M5</accession>
    <name>A0AAV4P6M5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_737531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004149">
        <property type="protein sequence ID" value="GIX92694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6M5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14232" checksum="34040EBCB9B22753" modified="2024-11-27" version="1">MGGGLFPHQSKCNIQESKRGGTCTCIHRYFQVIKHGEYKKLEEDRLFSFLSYFPSFSGEVFIPITGGGGMHGRVFLPYKLFTSSRWRCLRGRKWTENIVCVTLRGGLVAIRFQDRSGSEATLTSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6Y7</accession>
    <name>A0AAV4P6Y7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_757831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021610">
        <property type="protein sequence ID" value="GIX91715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6Y7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="12082" checksum="CEAA572DBAA8FE89" modified="2024-11-27" version="1">MLLPVASSTVVDFSVHFLLDICFLFFSPVVLETHFDEIVCICLVPDSRVPIREIEICQWGCCCWHRLGGRSLDLLTRRFLNCPTCFQVRLPPVSKFNATFSQCRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8S0</accession>
    <name>A0AAV4P8S0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_787851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004123">
        <property type="protein sequence ID" value="GIX92403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8S0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8624" checksum="0DB8E4C8460416CF" modified="2024-11-27" version="1">MQFTQSIGACSQYKRPPSPKAIKPRPRVKRPWLPHLEENKTNWKARTHRDAELRAQLSVVHDSSNGEEPPARVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PK74</accession>
    <name>A0AAV4PK74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_389191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004776">
        <property type="protein sequence ID" value="GIX97405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PK74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9571" checksum="85AA66C7B59683C1" modified="2024-11-27" version="1">MVSQYISLKEPSTQRIWPKASEYFPFVRIRGDMGPTPIVSSRLPLAKSNQLYRVSSGKSETICSSTHRSPWPFIGDPLGGEGEDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRA1</accession>
    <name>A0AAV4PRA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_718771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005067">
        <property type="protein sequence ID" value="GIX99586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10873" checksum="706B9879976CD32A" modified="2024-11-27" version="1">MSGGAETHCDWIVFRLKPMVLAQFNDEGKIRIIVSDLTTINGFQTVEADSHGTWLCYCGGRLHGTRGYVVRKVTSDFTATDLGNTIGSQIVELKPQDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PS21</accession>
    <name>A0AAV4PS21_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_690131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004937">
        <property type="protein sequence ID" value="GIX98624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PS21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050621">
        <property type="entry name" value="Tudor_domain_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948:SF65">
        <property type="entry name" value="A-KINASE ANCHORING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948">
        <property type="entry name" value="TUDOR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="1">
        <location>
            <begin position="71"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="25410" checksum="CA1500065325892F" modified="2024-11-27" version="1">MAITSEETPAVAALEDTSASSIVSEDTLAMLYSFTRPHFCTSSFRRFWTLKDFTDSLTSTCDHFPPPNMPYVKEGDVCVYRRDDFNFWCRTKVLNVLENGVAAIRFLDYGGYLIVPVQTLKQIPSEYLRLPFQAVECHVYDILPADSLQWSQQCQQEVHRLVFASSNAVLRVVVLGYNGEVPIVQVLYAPYAPHNDLSRHLISVGLARSMTVCARSTGALQFHCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTD3</accession>
    <name>A0AAV4PTD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_706721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005235">
        <property type="protein sequence ID" value="GIY00863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10698" checksum="AA1A015C33B6E652" modified="2024-11-27" version="1">MITRRNLSDRIFICNFSKRNEETPFLNQVATTCNVKRKSIGESETFRHSQSRIFILSRLCSVPGDIGNESYIMRDKFSKIFFSIRRIKDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q027</accession>
    <name>A0AAV4Q027_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_70743_1</name>
        <name evidence="3" type="ORF">CEXT_423831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005530">
        <property type="protein sequence ID" value="GIY03013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q027"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052632">
        <property type="entry name" value="MICOS_subunit_Mic19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21588">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21588:SF18">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY03013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="20157" checksum="CACE62698A37C67C" modified="2024-11-27" version="1">MGSAQSNRRVTVVNDDVVGVVQVSEGVARRLRGLPDKQETNSEKGTSEEQPIPETRPPPTYIPFAPPEPYSSTLEQRQKYHEEFKKSEKSWNNRIRELEIQNRQLFETANEKFTATVKDVEENHIKNSFAPVCPDKEQQVAKCYKENAKFPLNCSREVHDFMECVDKIRMTALSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4Q2</accession>
    <name>A0AAV4Q4Q2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">KMT2A</name>
        <name evidence="2" type="ORF">CEXT_389491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005440">
        <property type="protein sequence ID" value="GIY02388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4Q2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="203" mass="23642" checksum="9583D9423C381CC7" modified="2024-11-27" version="1">MNNFLGLKSCKDHNSEVSRNSNYLNDIRQEKQKIQLPRFNGNRKKCCNIKETQDCDKNLYDRDRKIKNVINNLENDCYDSGEDGEYNADKIQSIESSGYSSNEDNHLRQSRDPPNLPNQTSNRDLENRNINKSNSVEKSETLNCVSVWEKNMKLNGQKSFCSNLSTLNQKNCDKSTLNQILKQIYLEMFFLKKSIQVKKLLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4V0</accession>
    <name>A0AAV4Q4V0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_139221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005698">
        <property type="protein sequence ID" value="GIY04327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4V0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8392" checksum="4778FC39BCFC54AE" modified="2024-11-27" version="1">MAENQPLFFFHSQTNKQANSMESYHPIALTCTTCKLIGGHEGNDSCQFTDSLLLPSYRSRPPGGHRTHHNSLVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QB93</accession>
    <name>A0AAV4QB93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_365271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005952">
        <property type="protein sequence ID" value="GIY06385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QB93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11103" checksum="BFFA0FF8EC914911" modified="2024-11-27" version="1">MVLLHIPPVHQTLLLTGSSNSAAAARFVLMPDGPSNDAWLVGMGICDSTSSFLLFHDEEKYEISLETLGVNLQNMLIKAGQRFNVNPDNKVNNTQKKFLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBC2</accession>
    <name>A0AAV4QBC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_715531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006090">
        <property type="protein sequence ID" value="GIY07343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11654" checksum="AD93906BC23159D1" modified="2024-11-27" version="1">MYRYQLCPLSRYLSGNGCRVSVPAEPHYHNTPLYPQGIHNTIIFTLTFNSILNNCFASLISSSDPFWPIKLPNKAVITYDSKRRHEIFGTNAEIDGIASFKAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBK2</accession>
    <name>A0AAV4QBK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_797421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006047">
        <property type="protein sequence ID" value="GIY07078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15139" checksum="225BBEB72E99F90C" modified="2024-11-27" version="1">MEYLCYSFGVGQSSGCLWKGGPLIGEKKKAISLQQGFVYAKAAASSSWAEAKFSPFMTNPSSGANPDCDNKDESDSRLSLTRGISLLFLRRRTKLWMVLERGTSYRRKEKAISLLQCFVYGKAAASSSWTEAKFSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHY6</accession>
    <name>A0AAV4QHY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_202731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006414">
        <property type="protein sequence ID" value="GIY09668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14209" checksum="833AF077A48F549F" modified="2024-11-27" version="1">MLHRINELCLFHKRNVYENILVRYRSSCDNCTNSDGEGPKSYCENLIDDAFQILYKMKSRQDRPGICFGQAMGLTCPINRRGSTIPHFGYLKRWCSIHRTDDLRNIFKNSGRSSYTKKCTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPG4</accession>
    <name>A0AAV4QPG4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_234791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006468">
        <property type="protein sequence ID" value="GIY10062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11148" checksum="EDB95ECC2AEB7481" modified="2024-11-27" version="1">MEVAVYRIWMEVVYRMMEKWSGSVSCMDGISVSCFDGRSVSCFDGISVSCFDGRSVSCLDGRRGSCLMEEVDHVLMEEGSVLMEEVDHVEWKKWIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTK4</accession>
    <name>A0AAV4QTK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_388341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006853">
        <property type="protein sequence ID" value="GIY12795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15151" checksum="4350F3DE91F0F9C3" modified="2024-11-27" version="1">MRAKKEAAATATQEEKNIIATAWKKRIWELRLFSGRRWSRLPLWSPPIVDFCPKLYFAPLTLSPLFYCAKHKLTFFFITTPIHSLSLAFLSLSLCGSFCPLLVLFYGQKIVFNALFAVQSKMGQLFHSRGTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYI4</accession>
    <name>A0AAV4QYI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_630731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007103">
        <property type="protein sequence ID" value="GIY14550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14519" checksum="CB773714AE4D7B59" modified="2024-11-27" version="1" fragment="single">KTAILLTSRLCFISKLNEDHYKPTHKIENSVFLKRISNLLSEVQEPKKSCSEYNREKNSCARFVRSVLCENIYLCARKKIFCPQDRCTCSHLKHLFPFFFLFGSIPGCGYPLAISFSFAAKNVQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4S1</accession>
    <name>A0AAV4R4S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_602851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007251">
        <property type="protein sequence ID" value="GIY15594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14481" checksum="8E76AE4C1F21E939" modified="2024-11-27" version="1">MIPFSKFKDFRPSYDSTNNLSPFECRDCLDGDERFHSELCVCSLLLRVWCRLSLALIPAFVERTLRRCLFSIHSLCLPRLVAAPPLNRVYVRCFIRWASFSNEPVGQLSLLLIVYNRQNVSNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAF1</accession>
    <name>A0AAV4RAF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BTB and MATH domain-containing protein 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bath-43</name>
        <name evidence="3" type="ORF">CEXT_502901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007457">
        <property type="protein sequence ID" value="GIY17058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="11"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="339"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY17058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="501" mass="58221" checksum="32C5994DA54BD4DB" modified="2024-11-27" version="1">MACTTEEERKVFIITWSIKDIFYLKYSRLNSESFYPNTKDDTSFYLDLDMRGDNNNFISFYIWKTEENDTTEKDFELSMLAADGSPLIARKETKCLFTNQKQGFSNFGSRNEIFEHRKEEFLRNDTLILRCKIWDSDMTENVHFLRSICPDIHRANFVWTLKEFSTLTPDDAKTAPVKMPTRRDPLMDMKLFLMRREGQDKIQINLVNPKGSIVEYCSCSVSALDISGRVIESVKKEFLVEDDEDGNEGIIELPPFLSKRILMEQKDRYLPKDTLSLACEFSCYCGNETDISEGTYYGYDGDNLLKPQLSSNVCDDRQIVMTNPLGEDLNTLLQDRILCDVKLQTTTETFHVHKNILCARSSVFKTMFTNDTKASAKECVEIPDVDSDTMRQMLRYVYADTLNDLQWEIACKLYAAAVKYDIFSLKDKCSNFMKMNLCSKNACEALITSDLHQDVELKTSVQDYILNHVKEIIITDEWKDLMKNHSQLAAKTMYHRLLRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGA0</accession>
    <name>A0AAV4RGA0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_401711</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Antp homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007706">
        <property type="protein sequence ID" value="GIY19023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009952">
        <property type="term" value="P:anterior/posterior pattern specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050296">
        <property type="entry name" value="Antp_homeobox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45659:SF4">
        <property type="entry name" value="HOMEOBOX PROTEIN ABDOMINAL-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45659">
        <property type="entry name" value="HOMEOBOX PROTEIN HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="40"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY19023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18901" checksum="116BE7113397C3D9" modified="2024-11-27" version="1">MLFVLPSLDVISRMFAKLWCAMWGKIRCERHGRDKATEDVTRYQTLELEKEFHFNRYLTRRRRIEIARTLPLGEADQDLVPEPAHEVEEGAQAGLHHAPQIPQVMADHHPHHHHPHHPPRSPPARVLRGREVEDFLVEVSVALVEARGTKLPQFVCPVFQLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGY2</accession>
    <name>A0AAV4RGY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_400521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007746">
        <property type="protein sequence ID" value="GIY19377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9492" checksum="0B6A6BE66142F32D" modified="2024-11-27" version="1">MLFVCGGGGGRNATCVTKNLRFVKYNQKSFGVFYSNSCRLLGDNNRPWLASGKKWDGGTDNVCITDHYSSGFTVMSLSRIAFTIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV66</accession>
    <name>A0AAV4RV66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008421">
        <property type="protein sequence ID" value="GIY24564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9073" checksum="7563C399111A4C7D" modified="2024-11-27" version="1">MPLIRAYIQQARKTVEKMFVEFTKKIIPGSKYFLNDSKATYLSKAELFVVPLGSSSATMSKVMRNIVDKCNADKIPPSYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY63</accession>
    <name>A0AAV4RY63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_115721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008617">
        <property type="protein sequence ID" value="GIY26039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9926" checksum="B25A211AA2AF7CA6" modified="2024-11-27" version="1">MHITKSMPELKEKNEVLSSTLLTFLLQQNSPEVQEREFVAIAPGTPSPELQGSLSRKFCKIWWTDISARAPNRFRLDYNNGCFAIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2D2</accession>
    <name>A0AAV4S2D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_733831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008789">
        <property type="protein sequence ID" value="GIY27216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16711" checksum="0064A9967D4F717A" modified="2024-11-27" version="1">MEEKWPANLIIAVFCFTISIKLVDDPYQVWGADGRNVESDCAQFPSSLHCHIKHLHRKGRAISYSNHSLSFSFAFLFKNFLLMMSFPKDDKIFKMSLALSYECQLKNSNTVCRNWRGEKGICCRESFLRLFLESIKENICLLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2P4</accession>
    <name>A0AAV4S2P4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_409453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008938">
        <property type="protein sequence ID" value="GIY28350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2P4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19240" checksum="A12543D1D1CC2F6B" modified="2024-11-27" version="1" fragment="single">PEPNQEVDSCESKKTRGRKAVLKEPEPNQDVDSCKRKKTSGSKGLLIAPDSVQDEVCVGTLDETEESYKIESLNKSDAEFFYKTCSFVNIANKFISNHSLCDDIYERQLKSRTFLEEDHMMLSGKTEPNQEVDSCESKKTRGGKAVLTEPDVRKLKFPGTNLFEGYPYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S388</accession>
    <name>A0AAV4S388_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_809011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009011">
        <property type="protein sequence ID" value="GIY28973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S388"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8773" checksum="D726974B90BA147D" modified="2024-11-27" version="1">MPTKCFPLITFRRHNVKMFHPPPPPSPQTEEHPIAHSCNLGKDLPSSQEKYSQRGFNLLRLQRARLKRGREIKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4W0</accession>
    <name>A0AAV4S4W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_625361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008831">
        <property type="protein sequence ID" value="GIY27581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9039" checksum="4A83F22336B5D213" modified="2024-11-27" version="1">MPFYPSDKLGLSQHLTFANASGIHTFQLLTDRLMWSTLKNVLQPNGSIYLQTQKIEILHPTDKSQCLSHILLLTETSVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S517</accession>
    <name>A0AAV4S517_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_791121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009095">
        <property type="protein sequence ID" value="GIY29603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S517"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13289" checksum="D3299C6ED1449D2B" modified="2024-11-27" version="1">MKGTSAFRFFITQYRGAFQREPVGSASLEDKTEPFVKSVTKWKGIRGVCSVVLHGSFHFPRDFVDPLPVVSASARDVCDIDRMAALVHRLGDSSRDWVWCSRWGVPSGHPVVFWVCMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGD7</accession>
    <name>A0AAV4SGD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calpain-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CalpA</name>
        <name evidence="8" type="ORF">CEXT_765001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009477">
        <property type="protein sequence ID" value="GIY32226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000114">
        <property type="entry name" value="Calpain a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022682">
        <property type="entry name" value="Calpain_domain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01067">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="58"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY32226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="457" mass="51729" checksum="453471D4E3260AA3" modified="2024-11-27" version="1">MFQLDAILPPATFAVPMGCFPSVTTAAQGASIAIVEDLGFQTARDSSTLTNASEDDRLFLDNDFPPSEATLYHSSKRTRDPQIVWLRPHELIVRPELLVDGVSRHDIVQGILADCWFLSSCSAVAQRPDLMEKVIPSNQPLSGEGYKGIVTFRFWRFGHWITVYVDDLLPTKKRKLIFSRSSEPREFWVSLLEKAYAKLHGSYEALEGGQAMDALVDLTGGLAEIEIDCSVMYFNLLTVVSLSNPLVYVLGDWKEARKADANGLVSGHAYTISAVATVKLSTGSEAYLVRIRNPWGNDTEWNGKWNDSDTNWHNVDPNTREKIDYSKRGDGEFWMSYQDFCREFEEVTICSLTPDLTQHSTHRNNAVVVAKSNRENETKCNIVAALMQLRRRCVRHPQRKMLQIAFVIFKIQINPGHYIIVPATFEPDAPGSFYIRVYSDMQISLSELGNRWSDWRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJE0</accession>
    <name>A0AAV4SJE0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mutator-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_43574_1</name>
        <name evidence="2" type="ORF">CEXT_435321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009722">
        <property type="protein sequence ID" value="GIY34099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049012">
        <property type="entry name" value="Mutator_transp_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20700">
        <property type="entry name" value="Mutator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mutator-like transposase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY34099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12583" checksum="C51F5C059CA439DF" modified="2024-11-27" version="1">MQDLSMAGGRGLSAAFKFCATMNLPALSKSGYKKHEDKLLKVVRDVAEYSMCNAAKEVAETFNHDECGVSVDGTWQRRGHTSLNGCVALLSIDTRKVLDLEVMSSYCPICRKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQF2</accession>
    <name>A0AAV4SQF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_24551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009693">
        <property type="protein sequence ID" value="GIY33843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11877" checksum="272550A93B738924" modified="2024-11-27" version="1">MRSSTHLLFPRSASSKRLCSCGPGSRRALLFKGPGLSAPRVSSVRAQHCLTVDPARGRLLDYFGKAAGRFYSLLQEPSNLVCSVELPTSLPCPSLPYIFAWDLTRHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SRW9</accession>
    <name>A0AAV4SRW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_491951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009872">
        <property type="protein sequence ID" value="GIY35192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SRW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11118" checksum="CCD8595277A502E3" modified="2024-11-27" version="1">MKEIMPFAYPHMKTLFQTSYYSRFPRIWSNITPEHPIKSLCFLNSQLKWISYGRRKARDYVGVIRSQQMSLTYAKLKVSFAMGQIHALSIKIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSN5</accession>
    <name>A0AAV4SSN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_101341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009790">
        <property type="protein sequence ID" value="GIY34623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11156" checksum="0D642E30CFF40F3D" modified="2024-11-27" version="1">MDSKSRKLLQAFTVIEELLKKNEICIAVKERLTKDSEWLGIPTTTTLCKSSCPSPAPERPKDAYLFGKWRIMVPQGIAVKEKYRTWSNNSSAIRKKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1J0</accession>
    <name>A0AAV4T1J0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_699901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010535">
        <property type="protein sequence ID" value="GIY39955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1J0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20609" checksum="0D6940BAAFFD3CD1" modified="2024-11-27" version="1">MTTQSEGEGMGNPKYSFLLPHLTRKERGWRREERDNLWNKKDGVSMANLARCQQGRGRRSMPLPRWPSVRLSGASAGIQRGRILTLHPPIPSFLLVQGSEDPSKATLMKNREMFHKVSDLYPLAIFSIVFLETLPKHPFRSILPSPILLSVLCIFLNRMVVNNSLFSFFFSDTSVHIDSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKV1</accession>
    <name>A0AAV4TKV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_410211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011328">
        <property type="protein sequence ID" value="GIY45834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8191" checksum="576378BCBAA22317" modified="2024-11-27" version="1">MEREAKRCCHCPQKNEEMLDSPALCTRGNSVCNRIKEVVYLGFDFPSELEVKKKKEPDVLSTFRREIDSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TL17</accession>
    <name>A0AAV4TL17_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">COMM domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Commd3</name>
        <name evidence="4" type="ORF">CEXT_301331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the COMM domain-containing protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011381">
        <property type="protein sequence ID" value="GIY46176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TL17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017920">
        <property type="entry name" value="COMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037355">
        <property type="entry name" value="COMMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31159">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31159:SF1">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07258">
        <property type="entry name" value="COMM_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51269">
        <property type="entry name" value="COMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COMM" evidence="3">
        <location>
            <begin position="15"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00093469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY46176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9822" checksum="08841ABA2899B927" modified="2024-11-27" version="1">MLKILDSRISETHNQIIDVEWRQDFVIKSNNCEKICEPSYIISLKTWNPHSNSSENVPFSCTLEQLEDLVLKLKDATKCIERNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMD4</accession>
    <name>A0AAV4TMD4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sema domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_9691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011335">
        <property type="protein sequence ID" value="GIY45882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002116">
        <property type="term" value="C:semaphorin receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017154">
        <property type="term" value="F:semaphorin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008045">
        <property type="term" value="P:motor neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007162">
        <property type="term" value="P:negative regulation of cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050772">
        <property type="term" value="P:positive regulation of axonogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030334">
        <property type="term" value="P:regulation of cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097374">
        <property type="term" value="P:sensory neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031148">
        <property type="entry name" value="Plexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001627">
        <property type="entry name" value="Semap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036352">
        <property type="entry name" value="Semap_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22625">
        <property type="entry name" value="PLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22625:SF44">
        <property type="entry name" value="PLEXIN-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01403">
        <property type="entry name" value="Sema"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00630">
        <property type="entry name" value="Sema"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101912">
        <property type="entry name" value="Sema domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51004">
        <property type="entry name" value="SEMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sema" evidence="3">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY45882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="409" mass="44944" checksum="0247FF71F81D9C34" modified="2024-11-27" version="1">MVVDEVSRRLLVCGSVYQGACQRRELEDIAVSDDLVLLPVAANDETSSTVAFVGPARYMGYPSRVLYVATTNSRLGPYRDMVPAICSPTIAPSISGRRRIHITTGSHLCFGCRYDSYVETTLQCLGPDGRDYNLLQDAHIVRAEPADMLVGVFAASRDHTMHSSGRSAVCVFSLADIEQRFTENIHLCYNGSVPSRDMDYIAGSIQDCPEPGYVKPFFPTCFRHSEVPPACPKSLNPIFKGTVILLAGNYSVCLLTNFVPSDELLSAPKSACGFGIEIPVPSAAAETIHRPHENLVYSQPERNGPNSFIVPDRFTIGLKDNLNGHRSYRRSLTDCLRHLKGGNIFNFCGESLKLNGSLPPHFDPGHHVRESDAVFSGGHHHLPPHSGLHRHQKRTAEKGKSTSLVIYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRW3</accession>
    <name>A0AAV4TRW3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_495691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011482">
        <property type="protein sequence ID" value="GIY46803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="27190" checksum="26F35DC3831C3A16" modified="2024-11-27" version="1">MERMEFFARGCVQEKGGEAIRRDYENIKVPAYFTKLDDCKDAGNMKDLEGSHLRVPVSVHRQPSNVSRRSGVSGGDGGDISPRSGSVSESSTSPEKGTSESSSGVHSNSSVGNKRSSSMENVGIITFAKPPWKSMSLQRGAAPPTNETPYSHVFRQSNAMTIQRKTKKRNLDGTPNTYVEPFERATNVRLTSFTDHSDFPPVVATSGNSKSPLQYTTGNMQTFPTHQRRDSANYSLASSAESESSMQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TTR8</accession>
    <name>A0AAV4TTR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_205261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011812">
        <property type="protein sequence ID" value="GIY49259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TTR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10231" checksum="A6E843135C395780" modified="2024-11-27" version="1">MKSHAKKRKINQRRNPIKMAAKRRKSQSDSKAGDGGWEERRNRYPPIKCQINPTDGSFWNLCRLQFFKRTKFSRQMVAMFRSFHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWM9</accession>
    <name>A0AAV4TWM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_478821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011943">
        <property type="protein sequence ID" value="GIY50130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11192" checksum="575D031368849E7F" modified="2024-11-27" version="1">MEASLASGTEVPNPCCGHCLASAPPGVAFRYFLVHAHWSICVGGGVACRHPGFTGVSRGKQARKAFVLFLLFPAVTQQAMRDKKSSRFRNEECPPFVVSRHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4W9</accession>
    <name>A0AAV4U4W9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_624491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012288">
        <property type="protein sequence ID" value="GIY52785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4W9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8621" checksum="394072551735B3DD" modified="2024-11-27" version="1">MPPLISLRPNNARGPTYTERARAQLAPEDATDSHPMQLLLQRERVNPSFFCLSDYNLEWTLFLECSRNISGGEFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBD9</accession>
    <name>A0AAV4UBD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_588481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012602">
        <property type="protein sequence ID" value="GIY55063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10117" checksum="2DF3C9C9AB21FDF4" modified="2024-11-27" version="1">MSILTDISMEKSILTDTWKKSILSGISIEKVHPNRHIQDKNVHPNRHIHRKVHPNRHIHDKNVHPNRHIHRKKSNLTDISMIKCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UD58</accession>
    <name>A0AAV4UD58_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_766291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012664">
        <property type="protein sequence ID" value="GIY55672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UD58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="12424" checksum="637BB3C3C4FD3120" modified="2024-11-27" version="1">MVWFGLSPFVKEVFERITEKSIKRVANEKQRHIEIEKREKQRGFELEKLKLQNEYKVMVWFGLSPFVKKVIERIMEKSIKRMANEKQRHIESEKREKAKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UD81</accession>
    <name>A0AAV4UD81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_810361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012665">
        <property type="protein sequence ID" value="GIY55727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UD81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10409" checksum="19AC04932133F9D9" modified="2024-11-27" version="1">MYLYIPTDLYTRKRNGIGATICQVTTVTEVPYCAQGAHFHMTLFTAAPSLIGTFIPREAFQMKTGISPIFPIAVLFYIFMGLSKGINRIQMVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDG6</accession>
    <name>A0AAV4UDG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Gamma-aminobutyric acid receptor alpha-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Grd</name>
        <name evidence="5" type="ORF">CEXT_212961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ligand-gated ion channel (TC 1.A.9) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012673">
        <property type="protein sequence ID" value="GIY55792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19007">
        <property type="entry name" value="LGIC_ECD_GABAR_GRD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY55792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="25708" checksum="EC5111D3F0D32E39" modified="2024-11-27" version="1">MDCYFRQSWVDKRLAYSSNMPFLALSISMLERIWKPDTYFYNGKNSYLHTITTPNKFVRLYRDGRVLYSSRLTIRASCPMRLENFPMDVQRCPLQIGSFGYSDRDIQYRWNPLRSVVIAPDMKLSMFDVTDTPTGNLTEMHRKGPFSVLVVSFHLKRHMGYFVIEVYAPAPCWLCCRGWRFGSIEKRQQTELLLVRRLSDKYVRLVVIPQNRETFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJ94</accession>
    <name>A0AAV4UJ94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_589071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012967">
        <property type="protein sequence ID" value="GIY57822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJ94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10191" checksum="ABEA4AE1EF57AC07" modified="2024-11-27" version="1">MEGLGDIPGMLHLSTWRHGVAIPQLGAFPFDNLSVLIVPTSVDALIDSWIVLCFPFRSSPRNSESAFVIKKHRDLSGPLPLRSFQAMLCATAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULJ4</accession>
    <name>A0AAV4ULJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_135071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013082">
        <property type="protein sequence ID" value="GIY58602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10087" checksum="402FB45EFDC62862" modified="2024-11-27" version="1">MRVLPSNVIAQNLRILINCFNRGQEKPRIDCSPALPFQPREVGVEENAPRIRNSIISECIKRRFITWMGFQRKKNGKVRTGIKCHPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4USC3</accession>
    <name>A0AAV4USC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_425081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013359">
        <property type="protein sequence ID" value="GIY60687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4USC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14238" checksum="8D698C6411DD7F04" modified="2024-11-27" version="1">MENVQDQTTLSNIHLIFRVIRKYETQESNLCNLSLMSGVDLMEVFGSVEELDVYYSFLTQIKERNRGLLNYAEDLIDSLVAETPETLVNLRQQLSQNRRKHILCSGCFTLWTNNIKHKMQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXW9</accession>
    <name>A0AAV4UXW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium-coupled neutral amino acid transporter 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">slc38a7</name>
        <name evidence="7" type="ORF">CEXT_622081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013633">
        <property type="protein sequence ID" value="GIY62555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF652">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="6">
        <location>
            <begin position="150"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY62555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="557" mass="61638" checksum="ACF709D9F09024A7" modified="2024-11-27" version="1">MTGDVMTSRKNLHVTKVGGYFQRGSYFEQLARKWSSNQFYPARFGCLQKVLSGATWYSKSAQVQNGQIGEYQPLVHTINRNYSCNEIYQGKDGTETPIFPGHHINARRALWPSRSNLPLNLTPKTQSLSQMSVDLLHPLIPPIPEHEDGVSWITASFLLINAALGIGILNFPAAYDLAGGIVSATCTQLIMLVLIVLTMLILAHCSDVNLDVTYHDVLLSMCGRKAQKLAAVSITCTCYGVCVAIFIIIGDQLDRLTLNNFSHYEFKNNSCICLLLAVFLGCFWIDILSPLICWVSGNFCHAVSSVPNSLWILQTGYKNVDIKHEPESISQLLVVVPVLCLAYQCQEVVVPVYACMRHRTLGNFTKSCCFTMFFLFMIYSIIGCFGYLTFGSMVSPNVMKMYNAEDPVVMIGIGALILKMVVTYPVLALCGRVPWMACTPKYSDFQQLNSSKVKEPDESSLQLYGSVPLSSALNTSSIGTVIHALGSISAANVFIYPGICLMQVTLQTDPGMRRKKELPPHCCSNYLGCTWRLFFGLIIVDSLLNNSTTKTVESLCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4D7</accession>
    <name>A0AAV4V4D7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_171931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013948">
        <property type="protein sequence ID" value="GIY65007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4D7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12087" checksum="E9F5F487220A8CE5" modified="2024-11-27" version="1">MTRSCGDNGAAVVGGNCDDNHLGHCAERNANGALSFGVLGICYGRRPLFEIMNSKPSETRHAISPDSSMINLNEKKKKAHLINETHRYMANEALLSIRSGQRTLCISDTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VA73</accession>
    <name>A0AAV4VA73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_630501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014159">
        <property type="protein sequence ID" value="GIY66860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VA73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13794" checksum="884368FD2AE80208" modified="2024-11-27" version="1">MDLLRTIWKYPLRWKWTAMQKENKIEKVTPGGMCRQINTAYKEMDVIDSIVAQSKRSDLQQDYVQITERKFQKRKFLAEWVSRVHFPIVDCSLHNPKINASNVNNGNNSKVKVNVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAN9</accession>
    <name>A0AAV4VAN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_324331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014186">
        <property type="protein sequence ID" value="GIY67006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16824" checksum="C406E9EDDCDB0DE1" modified="2024-11-27" version="1">MKESQLAKITTGKVSNEFEVGLKTPRALGRDGICQFAELFENQTHSAGLTKSQENLGLMANNMKESHSCQHEGKPAGEDHKLEKYQNEFGSWPEDTATFIDLSSPPLDHYKEENIVCSVTGKSFGTILRRDYCRNDGLKTPRALGGTDLSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHQ8</accession>
    <name>A0AAV4VHQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_594271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014542">
        <property type="protein sequence ID" value="GIY69500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9241" checksum="5FD6993A061F4E4F" modified="2024-11-27" version="1">MKNPTEFFFPAIYRPQVSLFRAKPSNALMRTFRLRPPSLLAEGGCPQITRAQCGGGGDLFILEHSERVVIEFCCGEQLVPLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHU1</accession>
    <name>A0AAV4VHU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Carboxypeptidase A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Cpa2</name>
        <name evidence="13" type="ORF">CEXT_172481</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014611">
        <property type="protein sequence ID" value="GIY69922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.340">
        <property type="entry name" value="Metallocarboxypeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036990">
        <property type="entry name" value="M14A-like_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003146">
        <property type="entry name" value="M14A_act_pep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF91">
        <property type="entry name" value="FI01817P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02244">
        <property type="entry name" value="Propep_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="12">
        <location>
            <begin position="137"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY69922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="351" mass="39879" checksum="8DE0B3BB292D7054" modified="2024-11-27" version="1">MFSFVFQLEDELSLLLFCHVCLLINAVSTFQNFSGHKLLGMTPSNDEQVMALRNLMEDPEMDFWLEPTRELQNVSVHVPPQAAQKNWKAPSKRDCPSTPSLTTLKSIFSAMWIEREREENYPGIHLQGRTSGFAFDVYHPLDEIVAYLDDVSRKYPNLTKLINMGDTYEGNIIYLLKISSGGNDTRPAIWIDAGIHSREWIAPATALYMINNLLVNYGNDPYITGLVDTNDWYIMPLVNPDGYLHTWNWNRLWRKNRALAPGFPGVLICRGIDPNRNFDIFFGGPSTSSTPCSSIYKGNRPFSEAESSAIRDGVMSLRDRMRAISRCILSRRSGCPRMATPLSKHPISMNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VI16</accession>
    <name>A0AAV4VI16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_708801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014613">
        <property type="protein sequence ID" value="GIY69997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VI16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12216" checksum="D292068640E83942" modified="2024-11-27" version="1">MSIRTSRGGASELRASLIGSRGEKRERIVAYAQPDRRLDIYRLLWYIGYPSISKEGDGWISITHPLPSQFVRQNSMDRAHTPALDRLVDRPYEVLFFPRGLERIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSY3</accession>
    <name>A0AAV4VSY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Remodeling and spacing factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RSF1</name>
        <name evidence="6" type="ORF">CEXT_546661</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015076">
        <property type="protein sequence ID" value="GIY73377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031213">
        <property type="term" value="C:RSF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15543">
        <property type="entry name" value="PHD_RSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028938">
        <property type="entry name" value="Rsf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14296">
        <property type="entry name" value="REMODELING AND SPACING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14296:SF16">
        <property type="entry name" value="REMODELING AND SPACING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="5">
        <location>
            <begin position="360"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY73377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="396" mass="44890" checksum="9532FB6C65FD610D" modified="2024-11-27" version="1">MRHPHCNRLNKNSLLLPPPVKPKLVTTFTTDVNEDVQIVSSISSPSPTKKKKGRLRQRGSASKPQVTPSPSPEPVKTPVKSSRQRTPRNSKKPAATSGKDNFTIPEGFLEILSNQSDTIKSEPQRKSRNQRSKISTPSAVSSESESAPIKRSRRIQEQHQKKMSELAVEMEKEQRLLEQLAKKSVKKTATPPKSVPEPKISKAAKSKFQPPTPEETCMESKRTTRKMNSRSRNMTKMTLMYEDESKDSEFSTSRETEKSKKRRRGKVAKKGYKPWDLSSESSSSLEELTEEEEEEHEEEPLVFEVNEDEFACEEVDEDAEPIIVRRARTAKKQFKIGKISPTTPEDVNTEENVIVDDKPCSKCGKYDKPEWILLCDKCDNGYHTTCLIPPLVLIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W103</accession>
    <name>A0AAV4W103_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_766151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015404">
        <property type="protein sequence ID" value="GIY75879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W103"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7586" checksum="CCF334AB0CC945ED" modified="2024-11-27" version="1">MLSEHLAARTDSQSPAFFCLASCNRHECPDRSAPVIAGRPTSSLAGLACDSKRCGFCHPVSHVLRKKCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7P6</accession>
    <name>A0AAV4W7P6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_631791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015732">
        <property type="protein sequence ID" value="GIY78238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7P6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="474"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY78238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="513" mass="58437" checksum="840C25B1F348CB39" modified="2024-11-27" version="1">MDITICEFCKACVTNFEVHNCFNLGNQHHRSYANIPQSSSAYLAQNRDLRASQPVDYEARWSSMDQMNSSMQKRFLNNIHQRTGYEENAADEIFSQYGVTNPNPYNSVTSDYMFPGTHHIQENEPNSAYLQMPSEVFIHQNSQHYGPINSEHPTNIPVSVTERTILTGSQQTFGQRNVLMHQIAQHPSASSQMEFSGMSSTNNMSPHFSSVYHNFDQTDHTLTNRVSQYSEKSLGMPVLAIQNANYNRMNPTSRINCIQQTQPLASFSSLSCDVPLETSSYSMDTLYPNKEEGTLNHTETENPKYFASHFSLPCTSQNTVTYQEYRVNSPCSVKFKEDENYPKNKQWTDFSYGLAENISYNSRASQIHQHNFESGIKNSKIECHTWEHSNFVTSLSENKNACKISNTISASEVSGNLKKISEDKTFCRKACALKKLDVPQKPKTSYNCSKCPMTFRRKDYHESHECCHNVEKPYVCNFCDKAFSTCRNLGVHIMVKSDIHVRNAVNVFFTGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJU0</accession>
    <name>A0AAV4WJU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_779591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016173">
        <property type="protein sequence ID" value="GIY81828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15380" checksum="5799671F32DDA734" modified="2024-11-27" version="1" fragment="single">MYFESRFRYIVSQVFDTVTDFRFNLDCYRLFKIAFSWNNVLYSSSLINGKSVVDLVVVVDLLVVKIPLYSVSGILPHTHHTYHSSPVLVQIFWFNLKQRTLLCGLLSWKLVLVFQDLGIFHEGMEDVREAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WL26</accession>
    <name>A0AAV4WL26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ homolog subfamily C member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnajc5</name>
        <name evidence="8" type="ORF">CEXT_522231</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016327">
        <property type="protein sequence ID" value="GIY83033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WL26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061177">
        <property type="term" value="C:type Is terminal bouton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900073">
        <property type="term" value="P:regulation of neuromuscular synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051434">
        <property type="entry name" value="DnaJ_C_subfamily_member5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027:SF7">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY83033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="19814" checksum="7A249CEF94993EC8" modified="2024-11-27" version="1">MISKKTYRKLALKFHPDKNPNDPGAAEKFKDINRAHSILSDLTKRNIYDNYGSLGLYIAEQFGEENVNTYFVLTSGWCKALFVFCGIITGCYLCCCFCCCCNFCCGKCKPRAPEDSGDYCNLKEEYESGGSAPSSPIRTQPQSSEPMAMPAPGENVTEMTGLKSAQTVTYMTGHGVSTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPM6</accession>
    <name>A0AAV4WPM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_217851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016582">
        <property type="protein sequence ID" value="GIY84861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10734" checksum="97DB797AAB9B1090" modified="2024-11-27" version="1">MYEWPYVAVCGRALSFQIIAVLTTIDRLTLGQDLNKKRAFPIEKKKVALFLPLLCIILNFFGGGTFPLLALSFAFSLVVITSRFQLCPRNCPEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQQ6</accession>
    <name>A0AAV4WQQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_783131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016606">
        <property type="protein sequence ID" value="GIY85032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12425" checksum="3BE2BCE2ED24E543" modified="2024-11-27" version="1">MLLGRLKSLSTMFLVRMFTYKKWEFDQPIIHGIHRNCLALLMLSNFLKINIMFNIWETPADADSLHPAHYARLLRTSLSCTALVVRSLQSLHRTRCSSYRLLAIICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WY04</accession>
    <name>A0AAV4WY04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_657751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016811">
        <property type="protein sequence ID" value="GIY86524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WY04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="12642" checksum="6B3C045AE7C28FB9" modified="2024-11-27" version="1" fragment="single">LVNIKAASNIFGNAGIGLGRVLQSSIAANINLHAVEPSKMPSVNNNADSEPNDYKDLERNGSQESTTASLNTLSAFAALGLGRGMNRFRGQNVYGFLGSDGNCDSLEISVRITFKGFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8U7</accession>
    <name>A0AAV4X8U7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-dependent RNA helicase DHX30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHX30</name>
        <name evidence="9" type="ORF">CEXT_136771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DExH box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000040">
        <property type="protein sequence ID" value="GIY91686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8U7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002151">
        <property type="term" value="F:G-quadruplex RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000526">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase DExH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF257">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="295"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="502"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY91686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="898" mass="102257" checksum="B450F04DC48850C1" modified="2024-11-27" version="1">MLLQPLILLMMRKIKKLWKVSIYMKWPQKFCVSGISSKKTEAENLSFLHACQKMKEYGLLDKDNKPLIPDKTNFTEKFLKSSKCDLLNLFHIIWLKQGKKTDILPKFENTNVAGIFGKNSFWECQLQLMYPEKRFLKSSATRLKDAESIAAAKALFWLRDISFINNKNRLIQYSSQDETKLLNYHLAPYSICIPPLLQDKMTSMLHKLQEQVKEKDLSEVLPVNDNIDPKLNELPVRNIITEEIYHELSEAEIILRSRQMFEKFVSYFESSEPSILKMKNARISLPIADKRADILRLIDENQVVILSGETGCGKTTQVPQYILDHYIEKNKGANCNIVVTQPRRISAISIAERVANERGENKVGETVGHHVRLNKKLPKQNGAILYCSTGMLLRKLCSNPNLLGISHVIVDEVHERNIQIDFLLILLKRLLESNKNIKILIMSASFNTSVFSQYFNNCPTLHVPGIIYPVKEYYLEDLHKDIPGINEFGKNGPSLNVELVANVINYVHRSQKSGSILCFLPGWHDILSVQNKLLEICKDPSELKICCAHSRLPHEEQKNIFEHPPEGVRKVILATNIAETSITIDDVVYVVNSGLHKGTSFDGTQGIASLGTQWITKANVRQRRGRAGRVQYGVCYNIFTRNILQYMDDYPLPELLRTPLESVILDCKLYCPDSKAEDFLSTALQPPSRSSLQIGINELQMLAILDENENLTELGKIIVNFATHPRLSVALVYASLLGIKQGYDNYLYSDHLALSKIFDTWHKLHKTSEAEEFIKNNLLDEQSLHLIKDLKALFAESLFTAGIIEQKDAFSDPENKCNVNSNHPMSIFAALSVAFYPNVMKVIQGEISKGKLNKEAIVYSLVKGQRATFKRNLLLQMNVNFQVHGSLILWLYSPKLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCP0</accession>
    <name>A0AAV4XCP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_488261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017596">
        <property type="protein sequence ID" value="GIY92875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9699" checksum="656F97ABF58B0C75" modified="2024-11-27" version="1">MEGEYVISTMPKENDNNLQHPSYPNFMELPKLTLHQQIAELSLELSRTIYQQSLLSHFHNLRASYGKHILKYRLFSPTVPPCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDD3</accession>
    <name>A0AAV4XDD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_475421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017483">
        <property type="protein sequence ID" value="GIY91994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="45" mass="5071" checksum="1551C6401E19627B" modified="2024-11-27" version="1" fragment="single">LRIAQLACSGCISLQANYKARMRLSVDHWLLSYIRYGSNSLANGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFF9</accession>
    <name>A0AAV4XFF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_293861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017653">
        <property type="protein sequence ID" value="GIY93377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13138" checksum="A70C893E10BE153B" modified="2024-11-27" version="1">MEMRSPVREDLFIGFEWSEKAFVVFAVVERFSLGSWEISARGNRQSKPSPGSPAKTISDLPAQRLLIPDYISELPPHLQKQQSLLRNIEESLCSFFYEPRGRTYNFLVLSRQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIV2</accession>
    <name>A0AAV4XIV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_11211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000293">
        <property type="protein sequence ID" value="GIY93693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="22164" checksum="8CB762C883D41000" modified="2024-11-27" version="1">MIQSCKNKVFRFESNTTYAKRGIYKAFKVLTHHRIFGAYGLFVKEHVFLTRNFRSVWTLVKEHVFRTLGRESGTENVGEISWGLSSTAFFGTCFGSICSFLHLRLSHPGFDVCQKKIFGSVDQNIKDGERSFRFCLHLWFSQSVANFGTKISMQSEREKCLFEIDFWGGFSWLKVFTMSSSIALVFLIADKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK94</accession>
    <name>A0AAV4XK94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_73391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000408">
        <property type="protein sequence ID" value="GIY94610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12043" checksum="2E37B8737285F2EF" modified="2024-11-27" version="1">MGHDCCRIDDNSMVPNPKSEDGQDVVASVPAMSANKSLDQEISGRTRDKPAKKSHKTNGLTMLEPLECDVCSFEKRFKHYTSSVDFGVSLHKFNRTPFWLADVLFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN98</accession>
    <name>A0AAV4XN98_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HNH homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_630351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000490">
        <property type="protein sequence ID" value="GIY95238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="13027" checksum="34A46D258234100D" modified="2024-11-27" version="1">MEKATVTECEFSGWPSSEKQHGVQSRNEKHKRIPAGRGVIIPRQRVIFRVEKGFNHQSAEFCDWLPSSRERNNMACKARNEKIHRIPAGRLQRCLLHFKDQNTAEMRQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRI7</accession>
    <name>A0AAV4XRI7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyl-CpG-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_63191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018034">
        <property type="protein sequence ID" value="GIY96333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032343">
        <property type="entry name" value="MBD2/MBD3_p55-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16564">
        <property type="entry name" value="MBDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyl-CpG-binding" evidence="1">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9906" checksum="D872B3B2BF3FAF4A" modified="2024-11-27" version="1">MLLTKRKREDEKQENDLPPKINTSIILPIRQTASIFKQSVTIIRNQDSKGRTDITFSHGPQENQNNCRFAVRGMKLRLRSIATALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT21</accession>
    <name>A0AAV4XT21_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_86498_1</name>
        <name evidence="3" type="ORF">CEXT_151061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018207">
        <property type="protein sequence ID" value="GIY97738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="152"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="254" mass="29354" checksum="CAB87DC3C3E084F5" modified="2024-11-27" version="1">MVHQISNPIIFSLDVYLKSLAWPVFQFSCVYRDAANKVNSVFGYYKDGKSNSVTNVTGKNGAKPTSKGLKYRSNMGTYRQSSEENETDGNENEVEDVILNNNSMHIYLKRTLFQYQETDNKEGMERTGRVFAFPQDEDAEQTVVLEEMCGLAPSNFKLAATKGYCVFLKWDPPKNEELAPFDFYLTEVENNEENQWKIYHASRNHITSMKLCGLEPGDHRFRMRTWTNNPCQYSEPSNVITLEEERGISKQHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTL4</accession>
    <name>A0AAV4XTL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018283">
        <property type="protein sequence ID" value="GIY98382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9961" checksum="2C4E802B33FDE0A5" modified="2024-11-27" version="1">MGWWRILDVEMWLVTNESIKKNKLENSRSGEISTPDSELKVIYYEAYKFFPIISRQLEKSQKPQDVFLRSKKIRCTTGDCLKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWJ2</accession>
    <name>A0AAV4XWJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Abcc1</name>
        <name evidence="12" type="ORF">CEXT_517011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018428">
        <property type="protein sequence ID" value="GIY99532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="573"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="671"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="758"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="782"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="22"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="232"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="534"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY99532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="950" mass="107680" checksum="AD74FD694C96C6A8" modified="2024-11-27" version="1">MNAVFEKALMVSKQSKHIKMLMTTESDNVFQMICVLSEIWGAPIRFLIGTYILWYFLGPSCFVGIATGMILIPINVIVEHGTGYFRKKGFSKRAKEFGILTEFLQGIKVLKFYAWEDYFSERIMPIRKSEMSEIRKGEFLRMAFRFLILSAFSLVLLTTFSAYILMGNEIDAKTVFVSFYLIWLIRIPFRNILQLLAHFIQGWTSIKIIQKFLETKDLEDISIDEDTQGNSVLLTNASFSWESMDIPCLKHLNLNIPKGSLIAVVGETRSGKSSLLRALLGEMQKNDGIACVKGKMAFVGGEAWIQNTTLEKNILFLKPRVEKLYRKTLEACALLSEIDILPAGEETEIGHMGVHLSENQKLKVELARAVYQEADIYLLDNPLRYLESSLAEFLYHRVIGRSGLLKLKTRIFTTTQEEFLPLVDFILVMKDGRIIEQGTYTQLNEKQGHFVEYLRASKSTNAPNKVKRHSESQEYNELISNKFGKQSDLWYSTTVFPAKTETDYLITDEVTISLKGFGYKLAEFLKTIGFILAALSILIAGLACACEVASGVWLSGWIDDHVDIHNPSKNLLIYTGFICCQIVLTIICGLIIFAISTTAAEKLHTWLLIRIVRASQAALEMTPIQKIIQSFDTDFHYADIKIPETFYVWLMVLFRVITMLAVIFIISPYLIALSLPLGFAFFVVQKLYMSGWRQLQHLTSATSCPLSNLLEDSLRGSSHIRATNTSHIFCNRFHLKMDTYNNCSLLFFLTSRWLSSSINIITAFLVLLTALMATYMRDKGDGFVGLAIVYSIQVSEALTAMVYMNSMFNNDLVPFERIKSFSQMKQELEWEDPANRPYPAWPDSGQISIRNLSTAFGEGLYPVLHGITLSIKPGEKVAIIGKEESGTSTLLYSFFRLIEALEGQIVIDGIDISKLGLKDLRSRLAIIPQDAFSFYWYSEAKFGSKTGVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWU6</accession>
    <name>A0AAV4XWU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_425681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018323">
        <property type="protein sequence ID" value="GIY98660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="20215" checksum="0FD03099FEDD3EA5" modified="2024-11-27" version="1">MPTQQINYTSAAVWLMEPPDFLSRMPCWNRKGIMQMGLRQHVPMITSPRAWLNSKVPLWRTVTQDLTGRTNSYRYNASLNNKCRFCVDSKIPYHYERVVHPPEKRTVNDCTAHNPVGKSEMKTPICSSDRVPKSEISEWKWTFRKHKARLIYEVIIVTRRRKSPGSIPELQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWU8</accession>
    <name>A0AAV4XWU8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_91351</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in transcriptional regulation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001059">
        <property type="protein sequence ID" value="GIY99551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000218">
        <property type="entry name" value="Zinc finger protein 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001116">
        <property type="entry name" value="Zinc finger protein 562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF66">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY99551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20166" checksum="2736CD942F194DEE" modified="2024-11-27" version="1">MSAATPCFVPRFQHTFDRRNSISYATHPSESSVNCEKISKDKSLGRKACILKKKMDVPQKMKKPSYKCSKCLFIFKRKDYLDSHERCHSVEKPYVCSFCDKAFTQSGHLGEHIRSHSGEKPYTCSKCSKTYSENRDLKHHMLKHADEERCKCYYCGDEFSSEESLGGHKCRKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXR6</accession>
    <name>A0AAV4XXR6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_662741</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001060">
        <property type="protein sequence ID" value="GIY99557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000630">
        <property type="entry name" value="Zinc finger protein 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052795">
        <property type="entry name" value="RREB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46451">
        <property type="entry name" value="RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46451:SF1">
        <property type="entry name" value="RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13909">
        <property type="entry name" value="zf-H2C2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="329"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="379"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="608"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="751"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="779"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="635"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY99557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="804" mass="90918" checksum="02BCE42974B90FF9" modified="2024-11-27" version="1">MISKDQKECPKCSLIFEDSTSLTRHLKTHSFKNTTCPICFVSLSSASSRDRHLLIHSGERPFGCTFCDMKFTTNGNMHRHMQGHVMRGHVNHKKKMRQRKDSRSSTESSKSLEQGGESAKQESSKFIEYIKKLEFLEFTFTHKLEAELKEETTNTGEISSASRVINHESGLMENKNPKDDFLGFLELQPCKREAEDKAVGVGKNSEEKEPTNTFHLSTVKDGNYNSESLTLAKSAAVCNSRVAKENETSDILENSDQDFAKVSDIISNLESVPGATAAAAAAVSDQMDVDAANKKSVEKPHACAECSYRSADKSTLKRHMAKHKKERPHLCNICEKTFTLKSNCERHIREKHDLHSREEIIENVITRRENPDDPSEEPRKCKYCHHSFENEQALQHHLRSKSCKAKPFICKICYTGSSTKNNCFRHIEKMHPELFQSGMSNAEKNAIKIHYTIRTCYPSPKEDTQKNNSSENSILETSNLATTEIFFGETQEPQESLNEDSRTVAAEALLSLVQNGREMNDEPLNLSVRNKSTQEPSAQDLPDQDLAVRDLSALPLDLSHAGRKFFLDCYNLVPQQVGRLQEPVPKANVTPPSEQDAYPKDTPTTYEHECEFCEQTFSTKALKFNHIRSNHSVKERYLRYPPLPPNAPTDSRSRKRKALKNHNDNETKPYEERSSKIQYDANNLYSRGANSSDMENEDLASIPSVISTANSTNFLLPGALGTTDSSSINLMNFEGNKGETTTPNGKKGFPHRCSVCSQLFRWPSNLDRHVVKHTKVKAFECGRCNRTYTTSSNLRRHTLKKRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1H9</accession>
    <name>A0AAV4Y1H9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_106029_1</name>
        <name evidence="1" type="ORF">CEXT_595891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001146">
        <property type="protein sequence ID" value="GIZ00374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1H9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="18706" checksum="B9F9D9E29D63A7DB" modified="2024-11-27" version="1">MPLVPFIQSARENVCEGAGAPHKQPLTLPWADIGGGAPPSFPFSKKRIPLLRGEGARAFGIPSNTSNLLKRYVYQENIPDHFEYGATLLLSMYIIGDFRNLYNLVWDLPIGLILSSLLTDVFSLTIRITLLCKRKSIFSAMLHLQDVHASLQCTQLVNLSSNQPLVWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5I1</accession>
    <name>A0AAV4Y5I1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_168351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001298">
        <property type="protein sequence ID" value="GIZ01417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5I1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12695" checksum="7282F9C0003CA622" modified="2024-11-27" version="1">MILSLGDYETQLKYWTTTLLPDFIVCLLRCPRNENKSPLPNQSFLNCWFPSPCSASAVSLQPGPLIEWITHPLIPLHNPLSLHRRYFPVHNACEVSSRGARISRWRIRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6G6</accession>
    <name>A0AAV4Y6G6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_295621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001466">
        <property type="protein sequence ID" value="GIZ02494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6G6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="20430" checksum="F1752D545908C2DB" modified="2024-11-27" version="1">MDITTYKIIGYGIGELASAYSDGLHYSRAGNTSCYFCGKSIEQSKISDERNISHWLPSAREIFREECFCLFCSSEEATSSITSTLESALKETNSLLSCQVFKAPAKKIPALVNSSHPEPECRLANAEYFAHRLISEAPSSEVLRQILSALIVGVGGPTLHPVNGASYLALMNKDSKSGMQVLLESLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBD0</accession>
    <name>A0AAV4YBD0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_71991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019141">
        <property type="protein sequence ID" value="GIZ04801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18679" checksum="9940AC8E4A138A51" modified="2024-11-27" version="1">MSDVKLKAKTCSFPAHKVILSARSPVFKAMFSSDMRESMCDSVDIRDMDDEAVRRMLQFMYTTDVVDLEWSSASDLYAAADRYEVLTLKEKCSSYLKANLRPSNACAALLLADLHHDEGLKRLVQDFILKHSWEVMNSDEWKQMMETDLKLAAETMYLEFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YED7</accession>
    <name>A0AAV4YED7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_666701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001760">
        <property type="protein sequence ID" value="GIZ04585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YED7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12422" checksum="6CD7A71E13CF5ED3" modified="2024-11-27" version="1">MENRQSFASESSKTDQPKNIPMEAETRDIYAPSTSKQGLETSPQISRSHSKTSFKRGKKSRGFPKESAKTKSNLPSSTKSKQKSLQSCSNKRSLEHKGKSPISIEKEYPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4I3</accession>
    <name>A0AAV4M4I3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_135464_1</name>
        <name evidence="3" type="ORF">CEXT_721611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001833">
        <property type="protein sequence ID" value="GIX66934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4I3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX66934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10889" checksum="35B028026878B384" modified="2024-11-27" version="1">MVFLQQHVALISNPFAQVCPMCHKSFVSSDLLMEHMQIMHKTGNNIGMATSYPAAGKTIQPNKLYLRMLLNNLKSMITLSVFFSNGYDVKICHVIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M511</accession>
    <name>A0AAV4M511_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_725971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001855">
        <property type="protein sequence ID" value="GIX67161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M511"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9486" checksum="32BCDDD8FC852B5D" modified="2024-11-27" version="1">MDDLLVQTIRPPSKIKPLMKDQALKQWLGLKGNRVILEKGTDRHSKYVEGKIPPPNFSFQRDFHLTRYIYPSAYPSKAFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8W5</accession>
    <name>A0AAV4M8W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_208771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019479">
        <property type="protein sequence ID" value="GIX68328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8959" checksum="09036B9DA50782D1" modified="2024-11-27" version="1">MKIRTTKVDGLHEDALITSEIFQLLERRNIWNYLEEEIFGKKKKNLAWEKKIGRAGIQSGLKEYDRRIISIKELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MB41</accession>
    <name>A0AAV4MB41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Homeobox protein EMX2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EMX2</name>
        <name evidence="10" type="ORF">CEXT_53101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMX homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001984">
        <property type="protein sequence ID" value="GIX68636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MB41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007420">
        <property type="term" value="P:brain development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000081">
        <property type="entry name" value="Empty spiracles homeobox 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050877">
        <property type="entry name" value="EMX-VAX-Noto_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000047">
        <property type="entry name" value="HTH_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339:SF28">
        <property type="entry name" value="E5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339">
        <property type="entry name" value="HOMEOBOX PROTEIN EMX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00031">
        <property type="entry name" value="HTHREPRESSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="9">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="6">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="63"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX68636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15259" checksum="C0927501A1A467FC" modified="2024-11-27" version="1" fragment="single">PQNASFILHQFRKPKRIRTAFSPSQLLTLEHAFEKNHYVVGTERKQLAQSLNLTETQVKVWFQNRRTKHKRQKQEEEQQSRPSDGQSSGKGESNDDHPSSVSPAIEESDESMCEDEDECDESTFDDGREHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDN6</accession>
    <name>A0AAV4MDN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_100891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019674">
        <property type="protein sequence ID" value="GIX70405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9442" checksum="EDA91A303B194A41" modified="2024-11-27" version="1">MDGRKLTSQHVPHIRQSGICVIGSPLDFGRVILVLSYLAGEVLALQLDRSRVEGGNDRDWRQLAETAAMRSAPLRTAASPGLCQRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFG9</accession>
    <name>A0AAV4MFG9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_629541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019657">
        <property type="protein sequence ID" value="GIX70196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX70196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="10768" checksum="BE1446D847DD33EF" modified="2024-11-27" version="1">MKDKVLHWILLDIALVFRTALVRKTNAISIKQLWLLVALCDTKGSYLTSGNATSHRTPSPNRSTPEELNSDEILDGIFQDTPMKKPLFENQNSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMI9</accession>
    <name>A0AAV4MMI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_215811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019909">
        <property type="protein sequence ID" value="GIX73055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10169" checksum="26D026ED0F6A61A1" modified="2024-11-27" version="1">MVILSAIGNRSDRDLLLDKVLKRGVSRCSGNPTPSVEKSIALSTTGLKLFRDDKLPYSRMAEWLWRQTLKLPLRKLLLDENCGKNSPKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN70</accession>
    <name>A0AAV4MN70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_586181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002451">
        <property type="protein sequence ID" value="GIX73861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18803" checksum="C3C20975202883C9" modified="2024-11-27" version="1">MIRNNHWRRKDNVSPPLTGLCDAEKEITAYLLGVAMILRHVVTILNDRTVHLFTEQVATNGGNFSVELKVSQTTFPSNHPNVGRIWTARERLFRTALIWNRRWWKIPERRRCLRRRLMDIIASKCDPRNFHWSLEGALAEDLRQEQSLRRTVRLQFGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR05</accession>
    <name>A0AAV4MR05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_155791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020097">
        <property type="protein sequence ID" value="GIX74798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11988" checksum="DD864D6FCAD0B40E" modified="2024-11-27" version="1">MKSSVTEEKDYFNFDRNRKRFILFLASSASLKREAMRAWDLIKIETFPALVSLKRREEFYAGVGGRKVEWLLLLQQLLHKAKAIRGHRKTKYSTNYLYNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3G1</accession>
    <name>A0AAV4N3G1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_90921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002874">
        <property type="protein sequence ID" value="GIX78874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="16112" checksum="8746FD7DFF1F21FC" modified="2024-11-27" version="1">MNTFKYIILREEGSLNVSTLKRAIVQKCDWAYEDFEIAEMVQDSTMRTLQGRFRKEDDKNTCLRKSIDTLMTVGSNCSPTMATLKYMRLREEGSLKERAFKRATVQKCDWTYEDFFDSRDGVRLYEEHVARTIPQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N579</accession>
    <name>A0AAV4N579_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_102316_1</name>
        <name evidence="1" type="ORF">CEXT_632201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020508">
        <property type="protein sequence ID" value="GIX79553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N579"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13002" checksum="4C2AA4A3077CF1EA" modified="2024-11-27" version="1">MWHSKTKELQREQHSPHFLSTSIINATPLTLIEQQPSGLNGKTTISASVAAPAAVPRAVSPQEGTVVGPLKRGFCRRGGNRLVHPRLSLWGKPMNTRQRHRDPRYRKLRFQVNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCN3</accession>
    <name>A0AAV4NCN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_634301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003160">
        <property type="protein sequence ID" value="GIX81726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9695" checksum="3EBDA2FD6D53DF04" modified="2024-11-27" version="1">MIKHSIYNHATTKLKIHDDLTKMAGPILDHKHNFKRKESPHPLSKNQKKVSKTVDRVNYSISTLEQWKENVNTNVDTTRNKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEB6</accession>
    <name>A0AAV4NEB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_748681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003300">
        <property type="protein sequence ID" value="GIX83169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="18519" checksum="5F92140B89B6DE06" modified="2024-11-27" version="1">MEIEVDYEINMRTFPEDLLILADNTTMLILSAYHILWTKKFTNNERYLEFSRKYEQSLANNLHSDIFDWEFELELCPKYWSTDEATFRNCVRPIRYLAKLYPYNKNAFFYYSHFVLNAANFFYQLGLEEAPMLAFLEVILVAKSVFPNGVFDAVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEF6</accession>
    <name>A0AAV4NEF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Neuroligin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NLGN2</name>
        <name evidence="5" type="ORF">CEXT_225341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020714">
        <property type="protein sequence ID" value="GIX81794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043573703" evidence="3">
        <location>
            <begin position="19"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="58"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX81794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="20727" checksum="14601DC93FA4BB3F" modified="2024-11-27" version="1">MFSFPLIVSSVALGGIKSLFAPVVGFLPPWTTPPEAITASWIRWRPCTGCKRTLRNSGNPKNVTVFGHGTGAAFVNLLMLSPLARGLFQRGVLQSGSALSPWAIARDALTYTKQVAAHLNALQKDSAALITCLGKRPIDDILNAPLRIPDHLIAFGPTIDGVVIPGEPADLMEKQTEFFFTIRPSYWSQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK02</accession>
    <name>A0AAV4NK02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_220551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021030">
        <property type="protein sequence ID" value="GIX85142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11575" checksum="0053253851E9BC67" modified="2024-11-27" version="1">MNIHASSLSFTEEKSKTFVVCYYLPRHGPPATWDGEKWHFRCLLVAMGFVKRDTATQCDCFLDIFDLPPTPSGFGISSVNGMFFNRVRENKISFLLDSSNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPZ3</accession>
    <name>A0AAV4NPZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_294251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021081">
        <property type="protein sequence ID" value="GIX85619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10738" checksum="7776006D41E5BA9D" modified="2024-11-27" version="1">MGQCLGIYTMGQNIGSDLLFQTGHNTSLRTSGKVHRIAFIEDIDFSVEDTKTCYGTKATCPEFQERDFVSYWNSLSRKKFGLNFQLSSAICAWPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVM5</accession>
    <name>A0AAV4NVM5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_415111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003703">
        <property type="protein sequence ID" value="GIX87689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11725" checksum="96299584F8391AC8" modified="2024-11-27" version="1">MYSPQMLLVKPMGCIQFCEVRRLCTAHRCFLCSPWVAYSSVKFVDYVQPTDASCAAHGLHTVRRFCAVHGLYTAHRYFCASRVLYIVRLRFVQSHHMSILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZ11</accession>
    <name>A0AAV4NZ11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kv channel-interacting protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">KCNIP4</name>
        <name evidence="2" type="ORF">CEXT_779081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003835">
        <property type="protein sequence ID" value="GIX89196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZ11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF167">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8856" checksum="693FF444C03EAE27" modified="2024-11-27" version="1">MKAVGNQRNEHDNSDDIEMTFVRSKPQRIEALCRITKFTKNELKLIYQGFKQACPTGIVNEATFKEVYAQFFPQGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1W8</accession>
    <name>A0AAV4P1W8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021546">
        <property type="protein sequence ID" value="GIX91018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1W8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8300" checksum="B110AD48C84B2072" modified="2024-11-27" version="1">MESRQLSREDKLINMNWDLQIRALTVISHWRDLRRRRVPNVPELCGRIRAVVRAFSIFSRNLDRPEAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1Y5</accession>
    <name>A0AAV4P1Y5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_259801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021462">
        <property type="protein sequence ID" value="GIX89924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1Y5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="66"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="325"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX89924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="375" mass="41678" checksum="FD0CDCB64AC4154F" modified="2024-11-27" version="1">MGLDTSKDINPNAARGYILEKFTKHKGGVNCMIMEPEKYLMATGGEDKSIVLWRINTTPTQSKAILKGHTDYVSCLAFHEKYVISGSADCTIRKWDIATHECLYVFEGHTNRINKVLCAGDFVFSSSVDHTAKAWTLVTQKYEAVADVCLQTFEGHGKAVYPLVFIPDDDSPLDGKTITEKDTLITGSSDKTARIWSFKSGKPLHEKFWGFICITLAEEASIVFPLPVAYSEATPLFCLTVNKPRFEVNSFFNLSDISISSLYERGTKRHCKCLGCRPGRQNVVQWGGDGVIICWNITTGEIFTGCADTYSRMFKAKTGELKRVFKGHSKAVVHIEPVYDKVYTVSVDGTLRVWDTTGVSRGVSSDFQPVRIGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7P2</accession>
    <name>A0AAV4P7P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_599371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021644">
        <property type="protein sequence ID" value="GIX92000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11663" checksum="D4484743CE1E5C14" modified="2024-11-27" version="1">MEKWIKFQLENYEFQPTVHVHLQGWKMRQLANWMQNSQGGNLVTFDADVAESANQRKTITEDHQTSELNKGREITKTISCTKDRHFIGMWINRDGASFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8L7</accession>
    <name>A0AAV4P8L7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sh3rf1</name>
        <name evidence="2" type="ORF">CEXT_3641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021724">
        <property type="protein sequence ID" value="GIX92974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="348" mass="37982" checksum="5FC53297C015EBA8" modified="2024-11-27" version="1" fragment="single">YTRIAAVGNKPCCQDLKKKKNIVVRLGLELLEGIKNNVKRIGSNTDITPRSAESSGQQQIPPHPQLPQPLGSLPHELQVQQICEWCLKNSDLTFKKGDVIILRKKEWIKIGFMVSLEENRVLCLLVLFKLLYLYLLMCHSNWNFPISFVEMNAAARAVMKLSSNAQLSSRILPPVAPTTDSHFGNTATTSVSSAAQSPSYQESSNNPTMQQAISSGSNTSFSPSAFTSPIHNSSVPSQQNVSMAAYPGTSYDGQHHPGNLSHHRQSQPSVGPKSNSEDQQTSNEGVHDNSVVSKSRSTPSPAFSSVASVTPPLVSQRAESIGAQTPTQDNQEDGSVFLLHFHLQILQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8V3</accession>
    <name>A0AAV4P8V3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_508181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004125">
        <property type="protein sequence ID" value="GIX92433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8V3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="17092" checksum="63F107530520AA0B" modified="2024-11-27" version="1">MRINGVKPPCPQIIAWSPLSLIYLADANENLSVGFTVREYAERETRNAEGKSRTESKEQGDELSQTSIPQIWDLTPDREASRMCFRETSRFLKSYISLPRNEVISFIDCAVRNHEIRSTGNETFVIMQWASISIYEQAEKFMRQIPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PC19</accession>
    <name>A0AAV4PC19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_707691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004265">
        <property type="protein sequence ID" value="GIX93543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PC19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8336" checksum="C5B96CBED3D99020" modified="2024-11-27" version="1">MCEHDKLHIRNPTVDWTSTAYYATLDIHPHHLPNQFVRQYSMDRAHSPALDRSLLVDRRHEVLFSPGDLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHH2</accession>
    <name>A0AAV4PHH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_204542_1</name>
        <name evidence="1" type="ORF">CEXT_408481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004659">
        <property type="protein sequence ID" value="GIX96534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="34588" checksum="7629BED0063DC132" modified="2024-11-27" version="1">MVAQHLESYSEHDRREFPDSPRFIWRSSGNLFAHSFINTLTLQLKLGSHQRWAIGDLNPAWRRLPVTLYKHTYIHLNEYSKNILDSDLKNLKTLCLIFCILVLQIWCSSVENLLSRCSSFSCKLLEMPSNRIATLVLKRMVKFFLPPNHKLIEFSTVMFKSEIYEIQVAVLAFVRALNFKKFNDKDPQFVNVRSSLASLFNTALRSKNYIIRLEALSIFCVMAQFTDIRITQETIARFPDLYPEVKAYMSQIPQSGFLTNKDKFEIMEKQLCNTENEPELSVTLSEQSKSVLSLLLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLV8</accession>
    <name>A0AAV4PLV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_4731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004613">
        <property type="protein sequence ID" value="GIX96162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11770" checksum="E2F55E304FC63204" modified="2024-11-27" version="1">MNYQKLYIATNIDAMHPTYSPDFTSNYHLLLSMSSCIFRKTFQPVRRCQKWLHAFTTSKDVRCFQQTLSQLFIHKLLEKRGNSMTSDGVYFENTINLPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNJ6</accession>
    <name>A0AAV4PNJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_214508_1</name>
        <name evidence="2" type="ORF">CEXT_753411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004991">
        <property type="protein sequence ID" value="GIX98977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14100" checksum="55DC0D95BC2A58A3" modified="2024-11-27" version="1">MEADSELSFLMFTSTLFNSCSLYVGITCLRHPNDYLSIGGISAVLAVWSLFIISFTAFLVMVKTGSSIHELSSSTWDKVQQLIHAGQKLTSSQKRLLSIVEKELTMTVWKAASVKRVSYSLLWEPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUH3</accession>
    <name>A0AAV4PUH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_195636_1</name>
        <name evidence="2" type="ORF">CEXT_23171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004969">
        <property type="protein sequence ID" value="GIX98847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="27207" checksum="6FD193EF40D9C151" modified="2024-11-27" version="1" fragment="single">DDNWESKVHQFKRTFSRSPSDVRFEKLRPAATHPNLRKAARPIGGWLDFDIWMNLIPKGDHGTFSTSDEIEITKLSGKTRLPDDILTQDVANLSQEVRTTLALLQQKYECTVTLPQTSQSLETRPTLKRSSTNNNQQPRPSSIPRPKQTSTCWTIFCTKDQNGVLHFREIQGAVRVSPSEEKVTFLVGHSSTGEDNNYLLDFATPRALGQEKQALAKLQGWPLSVAHPMHLCLHHDLEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXT5</accession>
    <name>A0AAV4PXT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_220908_1</name>
        <name evidence="3" type="ORF">CEXT_300621</name>
        <name evidence="2" type="ORF">CEXT_802821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019386">
        <property type="protein sequence ID" value="GIX67238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01005446">
        <property type="protein sequence ID" value="GIY02438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY02438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="10878" checksum="8CD47B8AF9E4645E" modified="2024-11-27" version="1">MGLAPTLGNSPGQGDLLPCPLPARSLLNATFPSPLSKAGFGAGLFPFRSPLLRESLKAVLSPLKYGFLSIKPISRPRGETLLCSASPTDEHASRRRSFDRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZU4</accession>
    <name>A0AAV4PZU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_301541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005458">
        <property type="protein sequence ID" value="GIY02587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8825" checksum="98DB78DFF5A910A6" modified="2024-11-27" version="1">MPLASINASRTDARQSLFWKKGRFRGEMEQSEDSLVIVFVFFSLTLIRLSLQTHILKFRSLDRVEDSFFHYEPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q601</accession>
    <name>A0AAV4Q601_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_382651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005643">
        <property type="protein sequence ID" value="GIY03959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q601"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11660" checksum="6E9AAA71E69573DF" modified="2024-11-27" version="1">MSSEELATTCLIDFTLQRDSKRLVRIPSRVAWDECKVQSCDRELFHRDRSSPRQLQLDNDSGRATNRSPAGARVGGAAALQCATQSRRVGGLRARLSLRLTRASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6Q6</accession>
    <name>A0AAV4Q6Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_706601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005792">
        <property type="protein sequence ID" value="GIY05044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20706" checksum="52E1AED8E92F6EEE" modified="2024-11-27" version="1">MEMHRWNFYLEFQGPFRFPAKPWLSYADPYNEHCPLHTTDHVQTPSEPSVSPCLRALSKGHPIPRSRLHSLASKHLETPRLQQAVDAFPNWQSRTESRDVAWSEGPKCVTSRFLFSFLFSGKDRYTRRRNVPGEGECGMEGMTWHSVTPPPCVSLRRGHHSLSLLLFIDSNSLVPPSVGCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q971</accession>
    <name>A0AAV4Q971_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_70485_1</name>
        <name evidence="1" type="ORF">CEXT_110291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005770">
        <property type="protein sequence ID" value="GIY04911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q971"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="490" mass="57390" checksum="07731DC2BAC5F936" modified="2024-11-27" version="1">MPPISLYETCLDRIIELIKGKYWSEERENPFSRLPPKIVELLVEVCGTSQKIRKFSYFRMLLSSGKLRKLKLCFPVFFTDICIVLPQMLTEKGCINIKVLELDQNFENDESKWLEKLLQKLPLLESLSVRTLFNPQALMNCKRLKQVEIIPMFFITEESDFLSEAADTLSHLEDLEEFDIFKYTRKSSNFLKVVKLLNNHDKLTSLRFTDSSRAAHHIMANNTRGRHPRYGLRKCSWTIGIGSFEDITALKFSFLQRIISSVLLFPFVEELEILVLCEDCFEYLKRLKHLRSMKMKFHIDSTYQWNFSFLSGIGQQLRHLCIVSHQDVPVNAISKYCFNLEYLKIIGNATLCDSIKSSYNFRMLKRLEISLIDANSLLYVFQNVRNLKELQFHNAAVFDDLRLQEILNRDPLAFNHLDKVFVRDCMLSTEGFRIFLKHAVNLTTAYIKSSHFSVGVQTDFSDVIKELERDVIHNYFAVGHYFKNTSYFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMU0</accession>
    <name>A0AAV4QMU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_44591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006398">
        <property type="protein sequence ID" value="GIY09542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="53" mass="6065" checksum="9D69C83663E87D0F" modified="2024-11-27" version="1" fragment="single">MGCSPSKSSSSILVEQRRIPSLTQMNEFSMESQKESFLNDPVDEIDFPSEDFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNF0</accession>
    <name>A0AAV4QNF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_486981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006561">
        <property type="protein sequence ID" value="GIY10777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9114" checksum="947EB5FFB7669ACC" modified="2024-11-27" version="1">MPDTYETALPVNNILDNLKDHIIANGGNDNFVSNQELNLTSAKVVFNWLEKLFKDSMTDTEGPQFKTDAEKRDAELKAKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6N4</accession>
    <name>A0AAV4R6N4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_428541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007400">
        <property type="protein sequence ID" value="GIY16681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6N4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043853736" evidence="1">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21205" checksum="66D89E94796CD274" modified="2024-11-27" version="1">MAEWLWRQTKIAFIKCCCAMCGVIVDRHSENECLSETLRLRLKPSSHIQNALTLTTEFQSTYIIHVLPGWPSGYGCGLNLLSSNVICSTHGVMFDGHSGDRMTEWLWRQTKIAFIKCCCSMYGVMIDVCTGLEVTNYIDSCGIFKFSQIENHDVNYGTVLCSGWPSGYGVGLKLLFIDCIYPMCGKIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8V2</accession>
    <name>A0AAV4R8V2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[histone H3]-trimethyl-L-lysine(9) demethylase</fullName>
            <ecNumber evidence="3">1.14.11.66</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CEXT_659361</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="14">Probable histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:60200"/>
            <dbReference type="Rhea" id="RHEA-COMP:15538"/>
            <dbReference type="Rhea" id="RHEA-COMP:15542"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the JHDM3 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.66" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01007419">
        <property type="protein sequence ID" value="GIY16832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140681">
        <property type="term" value="F:histone H3K36me2/H3K36me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140684">
        <property type="term" value="F:histone H3K9me2/H3K9me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048512">
        <property type="term" value="P:circadian behavior"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000048">
        <property type="entry name" value="Lysine-specific demethylase 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF129">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE 4B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="JmjN" evidence="16">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="17">
        <location>
            <begin position="116"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="396"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="652"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="653"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="686"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00053408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY16832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="697" mass="79441" checksum="AA76905BDFDF1872" modified="2024-11-27" version="1">MEEFKDFNSYLEFIEMKGAHKAGLAKIIPPEGWKPRKKGYDDINLTIPSPISQVVHGSQGLYTQFNVQSKSLTVKAYEKLANSKKYQTPSHFDYEDLERKYWKNITFNPPIYGADVSGSLYDDDVNEFNIQHLNTILDLVKNDYKIQIEGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGAPKSWYVVPPEHGRRLERLAAGFFHDSRQECNAFLRHKMTIISPSVLKQFSIPFQKITQEPGEFMITFPFGYHSGFNHGFNCAESTNFAMPRWVEYGKRAALCSCRKDGVKISMDVFVRNFQPDRYELWRAGKDIGSHPEDPSRHYAAPPPIIKAAQNKNTKGTLISQKTKRHPVSKIGKSKRTLRSSKVNEWGSDEDTELYDVNDAMISKKPKITKKKSTQSNFSIEEGRSNEVEDEQRSENNEDMQVDNENLQEDVKDELVTCMETKDSIEEVINNDKCGDLKSCADSELVSNASSNKPKSEGEINEGKLTLDSFDNLGNVMDNPPELKPFWLPEMKNVDNNTTTNNNDKSNCLTIHDHMQLLSSKYPHLSQAINSGTFTVVPVNSIPDQSTQNISVHLENNSVSPNMKFKNVSPTLFSSHQPLVSQTWKCETTNKGLKIKIVQPKINESIVEYPNSDPAIHIEKNPHSQIMDNYPVSTSTTAIESSSKNDESQKPNQTKKSPHKQIKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R970</accession>
    <name>A0AAV4R970_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone-lysine N-methyltransferase KMT5B-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">kmt5b-a</name>
        <name evidence="9" type="ORF">CEXT_795921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007478">
        <property type="protein sequence ID" value="GIY17181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R970"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1700:FF:000001">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY17181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19859" checksum="0231BC445BB58BDC" modified="2024-11-27" version="1">MDPKEFRNKTLLVVLERQAFPLTSYTKASSKQNASQVLSAQELSENDDFSTSLVLDPFLNFCTHKMNTRFRAPRVQKEELTRIITNFCIHQDYEKAYKQLTSGEWANVFFHIKSKVQLTKFKEHIIRYLRIFDKHSGFEILPCSRYSTENYMGAKVCATKNGARMNVYPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAK4</accession>
    <name>A0AAV4RAK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_311041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007621">
        <property type="protein sequence ID" value="GIY18412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8197" checksum="2D5F39E957236933" modified="2024-11-27" version="1">MTLGYREGEETDEPTCRKSDNEAEQPVNREIAEFDHLNFEEYTSPCRDVDHLLSEGVHKSQQKMNHIFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RF80</accession>
    <name>A0AAV4RF80_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_576751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007671">
        <property type="protein sequence ID" value="GIY18762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RF80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031054">
        <property type="term" value="P:pre-miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19877">
        <property type="entry name" value="DSRM_RNAse_III_meta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044442">
        <property type="entry name" value="RNAse_III_DSRM__animal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="2">
        <location>
            <begin position="24"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY18762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8130" checksum="1809228FD9505947" modified="2024-11-27" version="1" fragment="single">MILNPSFNNAVTLRSMDGGEPDIPTYKVIECKGPTNTRVYNVAVYFQGNRLAVGTGHSIQQAEMDAASNALKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHY6</accession>
    <name>A0AAV4RHY6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_601041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007833">
        <property type="protein sequence ID" value="GIY20057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33765" checksum="3E58C5B21CB10D8D" modified="2024-11-27" version="1">MMSILSISGYDLSKLVTMADKMWEIKSTSYQNVAITSSSNDDVLVKLQGKNSQLSLEVNELNKGNFPCTNSLNSALEAFLLIETKGTPVTAWARLGKLKAAKKKEIRFHVTTRSLYSFEKLVGQPSASQISVDWRPCEDYRAPSNVLDRYPLPFLKNTAYHPQSNGLTEQQHRIIKASLKYHLQQNKTLVGVLLFVLLRLCAALKEDTWSCTCLPEEFFTKISNILHSDFVQRLQNIIRGLKPPPTTTHGNKTQPLKHSVPKKETEGKHPEGISLTNDPYATTRSGKTVRFLPDLKDYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMZ9</accession>
    <name>A0AAV4RMZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_428931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008153">
        <property type="protein sequence ID" value="GIY22469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9411" checksum="906F1D2A1A25E9D7" modified="2024-11-27" version="1">MPSSGVNRHWSRSGGHGSVFSIFFGDLGDGRGAPRSVPTKDESTRMEGSQKRLRKVGTRGWLGRRGCQRGPGMQGAPRYASELFMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV06</accession>
    <name>A0AAV4RV06_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptidase metallopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CEXT_251271</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11">Can bind about 5 Ca(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M10A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008356">
        <property type="protein sequence ID" value="GIY24140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030574">
        <property type="term" value="P:collagen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00094">
        <property type="entry name" value="HX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04278">
        <property type="entry name" value="ZnMc_MMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.110.10.10:FF:000018">
        <property type="entry name" value="Matrix metallopeptidase 25b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.110.10.10">
        <property type="entry name" value="Hemopexin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000585">
        <property type="entry name" value="Hemopexin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036375">
        <property type="entry name" value="Hemopexin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018487">
        <property type="entry name" value="Hemopexin-like_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033739">
        <property type="entry name" value="M10A_MMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201">
        <property type="entry name" value="MATRIX METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201:SF308">
        <property type="entry name" value="MATRIX METALLOPROTEINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00045">
        <property type="entry name" value="Hemopexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001191">
        <property type="entry name" value="Peptidase_M10A_matrix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00120">
        <property type="entry name" value="HX"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50923">
        <property type="entry name" value="Hemopexin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51642">
        <property type="entry name" value="HEMOPEXIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="15">
        <location>
            <begin position="4"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="Hemopexin" evidence="13">
        <location>
            <begin position="205"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="Hemopexin" evidence="13">
        <location>
            <begin position="255"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="Hemopexin" evidence="13">
        <location>
            <begin position="303"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphotyrosine; by PKDCC" evidence="12">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001191-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001191-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY24140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="379" mass="43327" checksum="8ADB9F2DD3D0134E" modified="2024-11-27" version="1">MHTNIKLWPTSMSSDLVRAEVTKAFKVWSDVSELTFREVKRLDADIVVSFERGKHGDGYAFDGRGVVLAHAFFPGEGIGGDAHFDAEEPWVDREMTGIDGVRLFAVAAHEFGHSLGLSHSSVSGALMNPFYQQIQDNFQLPHDDTIGIQMLYGARNPTRWVPLSPYIPPATRAPVPPTRRPMRPDSGAPYKPATQPPSRDVPKKPHTCNTTFDAISVIRRELFVFRGKYFWRLNKQGLMKDYPVEIKRFWYDSDLETVDAVYERPIDTKIVFFSGAQYWLFNGNSKEPGYPRPLTDLGLPPELKRIDAAMVWGYNGKTYLFADERYWRYDESEGRVELDYPRDMAVWRGVPYHIDAAFQYTDGHTYFFKGKNSGNSMIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWM8</accession>
    <name>A0AAV4RWM8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_807531</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008555">
        <property type="protein sequence ID" value="GIY25514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002326">
        <property type="entry name" value="B-cell CLL/lymphoma 6 member B protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="109"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY25514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="454" mass="52403" checksum="E6661AFE5567A98F" modified="2024-11-27" version="1">MDNRFFHLSILAKEASQRYIALQSKENIEARGSSSEGLRNVKKRNVLYRATVHRYSTFKSDEFKKKFTYKCMFSSSCNNIFESYGSERKAYNDMKSHLAIHLESITSDAPFNTKSGMRRRDSSKEGMNSFDYQDGIESSKRTKRKSNSRKENALTISQMVKNIRHEHDYTIPRRRKKRSKKSIKSIKSPNETSANFSLDELLKKSDNGVIENCILTPAFPCIYDTFDVAALCVVSDSEQVITTMCKNASVDINSTSSSEKFIECVDAVEPVLESVENVKIKTVTTKPIISKCKYSIENSENIQQFERELAVDLISKLKAKKGKKKKGPLICEICIKKNNLRKFTAVATLMYHYRSHAGIKPFLCNICKCKFTRRHTLNYHISIHEGKCRFTCAYCGREFRHPSHFKEHLRRHTGETPYCCINCKSKFKTRNTFKRHLKMQHQKLLTANGIMDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0J5</accession>
    <name>A0AAV4S0J5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_685611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008630">
        <property type="protein sequence ID" value="GIY26126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0J5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12068" checksum="7EB659C0F85554A0" modified="2024-11-27" version="1">MNASIHFNLCHPYYNQTKQRFSNSFITNHACNELAPTAHPTQPFSSISFNPPTNHKPPLALSITELRQALWRIHNRDPNHLLLRGTLHTGTGLLPSTGRQTPVQPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1G5</accession>
    <name>A0AAV4S1G5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_786591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008701">
        <property type="protein sequence ID" value="GIY26582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1G5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10128" checksum="FC806704A2F04D32" modified="2024-11-27" version="1">MSPGRLVIVASSTVSAFSRLLAFKTPLISRPICPPGLLINIGLAFNRTFDLRMEWAFRDGLLIILFVFQPEILGNLTHRLDLGLRNDQVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2N4</accession>
    <name>A0AAV4S2N4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Brain-specific angiogenesis inhibitor 1-associated protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Baiap2_0</name>
        <name evidence="5" type="ORF">CEXT_415621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008984">
        <property type="protein sequence ID" value="GIY28793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2N4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051764">
        <property type="term" value="P:actin crosslink formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030838">
        <property type="term" value="P:positive regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013606">
        <property type="entry name" value="I-BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027681">
        <property type="entry name" value="IRSp53/IRTKS/Pinkbar"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14206">
        <property type="entry name" value="BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14206:SF7">
        <property type="entry name" value="INSULIN RECEPTOR SUBSTRATE 53 KDA, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08397">
        <property type="entry name" value="IMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="231"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY28793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="396" mass="45296" checksum="842896EAF8DE3F87" modified="2024-11-27" version="1">MEIAAEKDTKLVGVTEQKRFQQLYKGRREAFLKCVSTLKKSRRKKNINTDKQLSHMKMMESTKERLEVFCNDSLKEVTIIQERVMYGTVLERQCALNRQFLIYHNKGCEILEEQLPHWERIAETRDKLPDSCASPVKNGHHTYSVGMEGVYSLDSMLDVVIRNNSIARSYGKDSYMSQTLRLQNSEDNIYARPIVRAKSEYCLPTSTPSQSPKSDVNHKRYSRIMEYNGDCETSYARVLYAYKPTGDHQLGLNEGDIVEYITEENTTGWQFGDNLTTKKSGWFPVSYTESIQDPSKYLYNEDFMDVKPPPPPPLPPNSKGSQEHTEYATLTRGKKLLPVNPPIIPPAFDRDGPVENGTLKAKHYASHPNIFESTSNTLGRNGVAYHNGQYLPSMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2Y4</accession>
    <name>A0AAV4S2Y4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_813881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008802">
        <property type="protein sequence ID" value="GIY27309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2Y4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12066" checksum="C538094C16E7495B" modified="2024-11-27" version="1">MLFSPAGMPFAHSQIKRSAPPDDPLELPPPPSRNCCKYRSLPHFPRKRRLTGFHCFIVREIFPGKGDRSASIVVSGTEMCVEWKDFYFADFEIHLNTRFEFPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S396</accession>
    <name>A0AAV4S396_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008907">
        <property type="protein sequence ID" value="GIY28120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S396"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9628" checksum="7B099D9D3B7F4549" modified="2024-11-27" version="1">MLLRKEEGEEGKGINTRMSLSNTQETIKEVYKIECRSFLLPGGCRIGGVEEWKLSYAVSKQFITGGGKKGGCCVALSWMKYRWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S584</accession>
    <name>A0AAV4S584_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heparan sulfate glucosamine 3-O-sulfotransferase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Hs3st5</name>
        <name evidence="6" type="ORF">CEXT_196631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008978">
        <property type="protein sequence ID" value="GIY28732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S584"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008467">
        <property type="term" value="F:[heparan sulfate]-glucosamine 3-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037359">
        <property type="entry name" value="NST/OST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605:SF65">
        <property type="entry name" value="GH20068P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605">
        <property type="entry name" value="HEPARAN SULFATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="5">
        <location>
            <begin position="29"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="165"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR637359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR637359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY28732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="25998" checksum="C2DD5D381AB2C7A2" modified="2024-11-27" version="1">MPYSFADQITIEKSPAYFITESAPARIRAMNASVKLLLIVRDPVTRLISDYAQLAANKARKDKALASFEELVLQPNGQVNTAYKAVRISMYSIFFEKWHRVFPRRQIHIVDGDDLVRDPFPEVQRIEEFLGIAHRISKDNFFYNKTKGFYCVRNETTEKCLNESKGRRHPQVSEEVIHKLRQFYAPTTACSSELLEEISDGPRNNSYVYTGSMLPLLYSPITYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7P6</accession>
    <name>A0AAV4S7P6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_174251</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009167">
        <property type="protein sequence ID" value="GIY30019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7P6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990907">
        <property type="term" value="C:beta-catenin-TCF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024940">
        <property type="entry name" value="TCF/LEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10373:SF38">
        <property type="entry name" value="PROTEIN PANGOLIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10373">
        <property type="entry name" value="TRANSCRIPTION FACTOR 7 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01366">
        <property type="entry name" value="c-clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY30019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="270" mass="30579" checksum="377E6AD7DBD2FCD0" modified="2024-11-27" version="1">MQLYSNYLFFNIKFNTKILKISGNGFLPGFLRNSETGTSVAIAETLPVYCCSIVFRHTPALYPPTSAGFRSPYSTALPVTSANLTRFSPPTFAIAVSGNFAPGPSSPRDQSRSSHCITPTTGACLITQLNKKYNSRLLCPPVVTTTTIPWRRKSTSRSLSMLFHVVHEGDESKGRRRMYLERECSYQPNSRPGTACREEEQAKYYELARKERQLHMQLYPGWSARDNCALQVKKKKRKKDRNQDGDGNNLKKCRARFGLDQQSSWCKPCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAZ3</accession>
    <name>A0AAV4SAZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Double-stranded RNA-binding protein Staufen-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">X975_25964</name>
        <name evidence="5" type="ORF">CEXT_529421</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009089">
        <property type="protein sequence ID" value="GIY29547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032839">
        <property type="term" value="C:dendrite cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098964">
        <property type="term" value="P:anterograde dendritic transport of messenger ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007281">
        <property type="term" value="P:germ cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035418">
        <property type="term" value="P:protein localization to synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19861">
        <property type="entry name" value="DSRM_STAU_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051740">
        <property type="entry name" value="DRBM-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032478">
        <property type="entry name" value="Staufen_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46054">
        <property type="entry name" value="MATERNAL EFFECT PROTEIN STAUFEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46054:SF3">
        <property type="entry name" value="MATERNAL EFFECT PROTEIN STAUFEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16482">
        <property type="entry name" value="Staufen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Staufen C-terminal" evidence="4">
        <location>
            <begin position="76"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY29547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="238" mass="25255" checksum="2463D07DA0255291" modified="2024-11-27" version="1" fragment="single">GHHIYQDTDKRKIYSDHEGEKLDNDGKMGRQLVPGLLLMPEASLSDQNSIQNYTIANSASLHRAPGGPIQVNKLLQTIAIIAQELLETGLSPTAEAIRKASMKPVTYQPLGGYKQKLLYLSEVLGLPVHFTDFPKGAKLEHICLVSVAISPSQVKHGAGATIELAHDQAALGALRCLADLGMEAVPDVKKENSTISGEGLYITPGQGPAPKLTNSPATDLGSNPKAGSTIPITAKDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBP9</accession>
    <name>A0AAV4SBP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Synapsin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Syn2</name>
        <name evidence="2" type="ORF">CEXT_491551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009434">
        <property type="protein sequence ID" value="GIY31913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030672">
        <property type="term" value="C:synaptic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007269">
        <property type="term" value="P:neurotransmitter secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020898">
        <property type="entry name" value="Synapsin_ATP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10841">
        <property type="entry name" value="SYNAPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10841:SF17">
        <property type="entry name" value="SYNAPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02750">
        <property type="entry name" value="Synapsin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Synapsin ATP-binding" evidence="1">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8129" checksum="B8C6825CDB937390" modified="2024-11-27" version="1">MSSKLTAVKYPSVVKIGHAHGGLGKLKVENHFDFQDVASLVAVSKMYCIVEPFIDAKYDIHVQKIGNNYKAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIC3</accession>
    <name>A0AAV4SIC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_693881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009437">
        <property type="protein sequence ID" value="GIY31952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11425" checksum="4C0C3F31349ABDA1" modified="2024-11-27" version="1">MFCLTKTKNRIKHGQNPPLQNKYISPCTGIREVSKFLYSVTFPRESCLTRKYQSRCISLKSSLVRANRGDKVSQLRNPLSIEFRGALARCQGDTVAANAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SS50</accession>
    <name>A0AAV4SS50_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ABC-type glutathione-S-conjugate transporter</fullName>
            <ecNumber evidence="14">7.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ABCC1</name>
        <name evidence="19" type="ORF">CEXT_738541</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>leukotriene C4(in) + ATP + H2O = leukotriene C4(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38963"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57973"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:38964"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.3" evidence="14"/>
    <dbReference type="EMBL" id="BPLR01010063">
        <property type="protein sequence ID" value="GIY36565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015431">
        <property type="term" value="F:ABC-type glutathione S-conjugate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000020">
        <property type="entry name" value="ABC metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000001">
        <property type="entry name" value="ATP-binding cassette subfamily C member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000074">
        <property type="entry name" value="Multidrug resistance-associated protein 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005292">
        <property type="entry name" value="MRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00957">
        <property type="entry name" value="MRP_assoc_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="541"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1022"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1104"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1205"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1236"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="18">
        <location>
            <begin position="329"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="641"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="18">
        <location>
            <begin position="980"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="1299"/>
            <end position="1533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="GIY36565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1538" mass="173089" checksum="6AEED00CB231677F" modified="2024-11-27" version="1">MKTPLLDEFCNSSFWDEQLLWNSTNPDLTPCFEKTVLIWAPCLFLWLFGPLECYFQKKSYEEPLPWTGANIARMLLAIILCVLSVLSVLDEVFNDQIGNFFVPTIVGEGLKAFTFLFALVLMLFNRKKGRHTSGILFIFWFFLTLFEIFPYRTAFINLQNETNLPSTFSFVTHVIYFPILVAELILSCFADIRYRHYPRSGGKPESPETRASFASKLLFWWFNGMSILGWRRPLRIEDLWELNPEDQTLHISEEFEKHYRHSTWAQPIFQAKSRSREDVVDLKAQDFEEQKLKDGTEYIVRNGRQDQPKEKINILRSLFKTFAASFFSGSILKLIYDLLQFVNPVILRLLIDYVKSSEPLWIGILYATLTFLNGTLQSVILGSYFHRMFLIGMRVRTALVTAIYKKSLVLSSSARKESTVGEIVNLMSVDSQRFMDLMTYLNLVWSAPLQIVVALLMLFNILGLSVLSGLFASIVLIPINALLASQIKKRQVKQMKYKDERVKLVNEVLSGIKVLKLYAWEEAFKDKINQIREKEVKNLKFIAYLNSLSMMIWNCSPFIVALVTFATYVFVDENNHLDASTAFVSLSLFNIMRFPLTMLPHLITTMVMVSVSVKRINKYMNGEELERYITYDTSNVLALSVRNGEFTWDHPQEDNKEKAAKSTLTNINLIVPRNSLIAIVGQVGSGKSSLFSAILGEMTKLSGSVTLSGRIAYASQQPWIQNTTLKNNILFSKAFSKKNYEDVIEACGLKPDLEILPGGDQTEIGEKGINLSGGQKQRVSLARAVYSSSDIFLLDDPLSAVDSHVGKHIFDKVIGPNGLLRSKTPSLQLKLILVTHSLTYLPQTDVIYVMKDGTIAESGSFQQLVDSKGPFAEYLAQYGSQIDESEDLSHIPPELVRSLSLKSNESTPGSDLEDSKQMTVMSVNRVPDRRSISLSTSVERSASLAKDGVKLINIETAETGQVKMSVYLSYFKAVGHKWVALIFVAYVIWQAFAVESNVWLSEWGTDELLNGTEAAAQRDYRLGIYGALGAGQAFAIFVGSFAVAYGTLVASNVLHNGVLTNVLKSPMSFFDTTPLGRIVNRFAKDVDTVDVTIPMTLRSWLSCLLQVISTIIVITFQTPLFLVVVLPISVIYYFIQRFYLSTSRQLKRLESITRSPIYSHFSETLSGASTIRAYKAEERFCTQSSSFIDNNQICYYPSIVSNRWLAIRLDFCGNIIIFFAALFAVLQKDSLDAGKVGLSVTYALLVTATLNWLVRMSSELETNIVAVERILEYTCTPTEAPWLIEGKKPQAGWPDRGTVKMENYSTRYRSGLDLVLKQISCDVKSGEKIGIVGRTGAGKSSLTLSLFRIIEAAEGQINVDDLNIADMGLHDLRSKITIIPQDPVLFSGSLRMNLDPFDWYSDVQLWEALDHAHLKSFVSTLNDGLEHEVVEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDSLIQATIRKEFADSSVLTIAHRLNTVMDYDRVMVLDQGRVAEFDSPEVLLKDKGSIFYGMAKDANLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SV11</accession>
    <name>A0AAV4SV11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_268411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010270">
        <property type="protein sequence ID" value="GIY38188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SV11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9211" checksum="2F999B5169B2B107" modified="2024-11-27" version="1">MHQMLDTQTWVRFPSSTVILLNRKQRLLGRWNSITVTNGSIGPPSLYPSDSAMALVSNGSASHWDIVLKDKFPITWARNCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1K4</accession>
    <name>A0AAV4T1K4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exportin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_08385</name>
        <name evidence="1" type="ORF">CEXT_285461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010434">
        <property type="protein sequence ID" value="GIY39241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1K4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19626" checksum="791AF4FC53261695" modified="2024-11-27" version="1" fragment="single">TESIHAVFVCTAFDSLPRWLDTTANIKAILLSELVFDKIMEEGLVQQIQEANYLLQSVLYGIQELGEHEPNLSSLLSFGVHVYEELRHCFEIFNQHLCHLLLVINKVFENLMKLSLRLQKNIGQRHKKVVVIKDLPPLIRLKQKEDSSLLDIEPNDNIGLCNLFSDNQNSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBE7</accession>
    <name>A0AAV4TBE7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_436801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010998">
        <property type="protein sequence ID" value="GIY43620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8575" checksum="70F36BDABD00124E" modified="2024-11-27" version="1">MEWKSPCSQSEMSLGAPDLRVCFPKKRISRSSESSVLDAMLEGTSGDYLIKIRRYNEDTISVCGIEHFVLYLKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEA2</accession>
    <name>A0AAV4TEA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_447331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011012">
        <property type="protein sequence ID" value="GIY43706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14826" checksum="FB3C8445B5AA3703" modified="2024-11-27" version="1">MNNLLEVPRFSQGVALRFPVPPNAQPGSMISATPRYSNHVRGIDNPLSLEASGGRACVRSKTLIPHCSKTNSVVKWSRQACFKMQGSHSEGLWLFSEGSPVAFNTIRYCLFLVLNSSWACFYCEKLIFNNGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFX0</accession>
    <name>A0AAV4TFX0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_667461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011279">
        <property type="protein sequence ID" value="GIY45503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10336" checksum="5DDC6FF9F48A0078" modified="2024-11-27" version="1">MASADQEFIKQLREVFDLCDELKCGIISVNQLRDIVRKHFGGSEEYTLVLDVLECCFTGDREKGGGKPTIYTETIGGTSGLEEFRAVCGAICPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVH9</accession>
    <name>A0AAV4TVH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory-associated protein of mTOR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RPTOR</name>
        <name evidence="2" type="ORF">CEXT_65181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011941">
        <property type="protein sequence ID" value="GIY50119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000072">
        <property type="entry name" value="Regulatory-associated protein of MTOR, complex 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="541" mass="60193" checksum="8973BAE542CB2F3E" modified="2024-11-27" version="1">MSFSGDGNSLALDRLRRVSSSTSISSMVSSGIHSPYGALGYASVFGNIWKTLITLSCDPYPEVAKLAEQLINYIRNKVNEIHHSVATKNGKIPSMSEPSSPSGRPSFLTGESPPARPNGVAHTGQDSSRLGKPANRWTDSNAPYQQYQYFAQFNPIRKTFDKGPRQIREVGEESEDSQEPKTPLIETEYVAWSTKYFSQPVLKMNENDIDKKKLENSRIDEQIFINKNLNLPASLKFHPYESHMVVTDKECFSVWDWEKGYLLRSDNARNHQNVRITALDFLNAHDDTLLMLGSDDGVIKIWKNYVSDSENRLITAFQIIQDLLPSTRGSGLVLQWEQHASQILASGDVRHIRVWDAEKEMKIQDIPTGADSCITCLTSSANYASLIGAGCGDGTVRIYDRRMAHNEGCLQIFQEHSGWVVNVMLQNKQNFGQVISGSVAGDIKFWDLRQTSSMKNIPPAHGMTAMAIHPQLDLIACGAATHFISIYNQNGDNISTIKYHDGFMGHRIGPISCLGFHPYKASLAAGSTDSLISVYSVNKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3V0</accession>
    <name>A0AAV4U3V0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_415391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012237">
        <property type="protein sequence ID" value="GIY52410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3V0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15179" checksum="9E58F9818AAB4848" modified="2024-11-27" version="1">MFRRRFVTRNGLLDLLSAVYGFRVRLILLSPDARVALQGEQPIKCHYCNFRTNHGDLAGCLVVSSPSVRNAKKLRYPAHFAGGAPTSSFSSYFLVQCLVWERDSTEFVWFSNKNKLPVSFGNETQQNLSLACSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBZ9</accession>
    <name>A0AAV4UBZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_597831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012631">
        <property type="protein sequence ID" value="GIY55319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12264" checksum="19FA90B58BF394A6" modified="2024-11-27" version="1">MRKCGQNEASNCGLDSPPLCSRDPKMANKAECATGGSKIKTAFEANLFCVLNLSKRSPMEVYIKCFPPFFFSGWGSEGARCCSKMRKCGQNEASNCGLDSPPLCSRAPKVAVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJ63</accession>
    <name>A0AAV4UJ63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TD and POZ domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Tdpoz4_15</name>
        <name evidence="1" type="ORF">CEXT_383901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012955">
        <property type="protein sequence ID" value="GIY57749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJ63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23796" checksum="C76FF7F6CE54923C" modified="2024-11-27" version="1">MFQINITEKGCKTEKIRNLSSEVLDVLLLYLVTDNLEELEWEKVSKLLHAVDKHPIVDLIKHCSSFLSTHLSATNVCDVLVFAETYKNTELKMIAQEFISSHASEIFSSDTWTKVYDTKSSKLAAEILLKYCITFLQYKKIELKMSVQEFISSHASEIFSSDTWTKFMIQNPKLAAEILSITFLQYQTIELKMYKCPRIYFFTCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMQ8</accession>
    <name>A0AAV4UMQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_592811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013145">
        <property type="protein sequence ID" value="GIY59000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18735" checksum="30BD0BA860CBD2FF" modified="2024-11-27" version="1">MFAFSMYYAAEAQEICVYSAPVSHPDLFKVAIQLKSRFSLWKKVSGSPFSMYYAAEAQETLFTYITFLELHMDTYWIFGYWIPTQLTELLEDGCGRISVLRCVAFLCERDTADKELLMRLMELYCCVLAKDYNTRTSARQCLGGIKMRPQNRPLASAGMFNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V836</accession>
    <name>A0AAV4V836_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_161261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014020">
        <property type="protein sequence ID" value="GIY65700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V836"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="52" mass="6000" checksum="346FE264883C93F7" modified="2024-11-27" version="1" fragment="single">NVCVRLSITNWNLHSNKKGLIARSPPGLAYEDSRKERRVSQQYCTESPDHMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VA15</accession>
    <name>A0AAV4VA15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_598761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014166">
        <property type="protein sequence ID" value="GIY66893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VA15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10033" checksum="F60FB6D39FF89F03" modified="2024-11-27" version="1">MTALGSYLNAKTKKTHIKQGIVLDINNSENINEGNSQDTLKKVAASPDPAMNCLAFVEKHLEEQCFVANRMGILISQAYHEHDWRFGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMR3</accession>
    <name>A0AAV4VMR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein XRP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RP2</name>
        <name evidence="1" type="ORF">CEXT_640391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014819">
        <property type="protein sequence ID" value="GIY71517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12952" checksum="56C7A29BDC469350" modified="2024-11-27" version="1">MILLLQKEKEIGLCCPRMPELRDFFPLPSPEKLGDLQIMTDPKVVLFIIACIQLFPGPVIGLEYNGKDCINMCLETAKNIATSTGCTGLVYVSTCPKTARKQIESFFSHADVQLSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W222</accession>
    <name>A0AAV4W222_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_314181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015531">
        <property type="protein sequence ID" value="GIY76776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W222"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11360" checksum="4E0C247B6B61C8F2" modified="2024-11-27" version="1" fragment="single">LNPDCRAKPSKRTAFGKSKICGRNCAEAFNLQSIYYYRRDGPRGHSLERRARFPRKTGRIRTDVQGWRSSLFRMMDQASVSEFIRNTLSGGMPVKRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3Y9</accession>
    <name>A0AAV4W3Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_91510_1</name>
        <name evidence="3" type="ORF">CEXT_506701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015616">
        <property type="protein sequence ID" value="GIY77387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056707">
        <property type="entry name" value="DUF7805"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF3">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25090">
        <property type="entry name" value="DUF7805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7805" evidence="2">
        <location>
            <begin position="190"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY77387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="413" mass="46977" checksum="6BF59F76CB6169BE" modified="2024-11-27" version="1">MTFLSSTAIRGSGGPHFTARYEVVENIPYKDDILTNPCVLKINSLDTPKGSLESPRNVFLYGRGGSRDLVCKYELRGTPEQKVRITVQGTYFSSSALCETTYDTVIERHKCNVFHFGKFALINVTELWQDSRIFVGCICDSNKNFVLESIGHMLDIEYLVRNMGPRDDFRTFHFTLDYEFVPASSVCKTSHTSETNVMSGSKGQLVLNLHNVVPFRCRWLLAAFPTRALYLTVKGRVFDSECRNKILFYNINNWEPFKVFCTSEIDQFETFFTQSWKPDPSRSFEADLTLLEYIFNEPGQFKVNWIEVTRPKGKPCLLECPELEACVGEDLACDGIRHCPVSGNDENPDRCNQLPLLTIAISSTAAVAIVTLLVLCVLLRYRLVRSKDKTVIPPPDMYRSDCKHTFTNKAPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W702</accession>
    <name>A0AAV4W702_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_91510_1</name>
        <name evidence="5" type="ORF">CEXT_506711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015616">
        <property type="protein sequence ID" value="GIY77388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W702"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF3">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="37"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY77388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="328" mass="36668" checksum="E8F7086AF5FBA786" modified="2024-11-27" version="1">MEVEESGPVQIESPPTRVRRRTKKKAQPSRLAGGAKCDMMLTNCHFRECVIRSPNFPGFYLRNITCHYWIRQDFVPPGKIAQVEVYQDNEFKINIPSGHSNSDRYKPGTLTSDCAGDVVKVFDGRTTESPLLVEFCGAGPLPTIRSSGPDILVKLTSVTSQTLSNSHFELGVKINFAKSSSTFRIASEGCSVTVDGGRHPVGILQGPDHSVPSGTTCTYRVTGKRPTDRIWLYFSSYHVPDLNPWTDHEHCDVGKLEIMHPIPKIRHSHHHYHHYQLANTLSNEQNIGSESVLIETYCEKRSPRQCGHASDFVDLIPSRPCTVLTKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9B6</accession>
    <name>A0AAV4W9B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_313451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015896">
        <property type="protein sequence ID" value="GIY79495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="262" mass="30662" checksum="39FB96C751F967C6" modified="2024-11-27" version="1">MSDTEKKVRFGDVTVLEFEVEPYPRRKLLYVCTMGEVVWQFVFFNLFSSLLTFLLLIEVRGEPNKLKEKHLWVYVLCIWPAIAIIVSAMYHKQQLLALLRRNTGEMELSVATELILFPVLRTILLCVGISFLFVTADSIASVYKKLVTMDNMNRAEEPLNQQEPSNWMHCSNKELFVHLGIAGAFSLYTILTFHDEIRPKKSEEKAGDVHFLMILPVFWIYTAFSFYLFHRIPHITERIRQLAERRRNIAVAYLRADERVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDH0</accession>
    <name>A0AAV4WDH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_88270_1</name>
        <name evidence="3" type="ORF">CEXT_122411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016060">
        <property type="protein sequence ID" value="GIY80901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY80901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16174" checksum="D362E383471E8C64" modified="2024-11-27" version="1">MPETKRNEFPETVDHAPPKVKRTDQVPKVAVPPDGGWGWMILLGTMTVNFVIIGHGKSFGVYFRKLMEEFDASPSRVAWLQSLQISMFCFLSIFTKIEFPLLLGKSAGENEERINYLFPLTSERRDSSSSLRIFTAKLEEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIM9</accession>
    <name>A0AAV4WIM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclear transcription factor Y subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Nfyc_0</name>
        <name evidence="1" type="ORF">CEXT_652702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016159">
        <property type="protein sequence ID" value="GIY81719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="218" mass="23827" checksum="E956A2E94E8B0EED" modified="2024-11-27" version="1">MLHQHSLCQNVLQVQAVPTETAQQQAQAAQVQVQQVQVQNNQQTSAQQVLQLQQPMANQVNQPGGGIQIVQQFLNTNGEIQQIPFQLNPSQLQLIRMQMQGQNTNQPIIIHAAPVQQNNSPVQQTATQVSAENLWNGVSSNQPQQYSQGTVFQQANQQLTQQQQAQAVYQIAQASGQSGTPVFLTQTPGGGTATVQIQAVTADQHSSTDEEQQQSNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTN4</accession>
    <name>A0AAV4WTN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_737361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016670">
        <property type="protein sequence ID" value="GIY85628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13439" checksum="7C8786F8704D9A12" modified="2024-11-27" version="1">MVLSSNKEQIKAKVHMPIQNGEYKKYVRPQVVQLNSSRREDHEPSHYTFGNKGSLKQCSDIAFRSEPFMTRCHSELNHSNQMQFRSEPFKMPQMQFRSEPFKTRCQFRSENHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WX53</accession>
    <name>A0AAV4WX53_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">RNA helicase aquarius</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Intron-binding protein of 160 kDa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">AQR</name>
        <name evidence="21" type="ORF">CEXT_60391</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="14">Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE. Identified in a pentameric intron-binding (IB) complex composed of AQR, XAB2, ISY1, ZNF830 and PPIE that is incorporated into the spliceosome as a preassembled complex. The IB complex does not contain PRPF19. Within the spliceosome, interacts with SNRPA1, SF3B1, SF3B3, SF3A1 and SF3A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the CWF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01016931">
        <property type="protein sequence ID" value="GIY87372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WX53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000396">
        <property type="entry name" value="RNA helicase aquarius"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="19">
        <location>
            <begin position="3"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="20">
        <location>
            <begin position="102"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00057313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00061244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00063921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00069875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00083796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="GIY87372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="318" mass="37514" checksum="264A64326FED809B" modified="2024-11-27" version="1">MEESAQILEIETFIPLLLQNPHDGFNRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFGCPGRSRPSICELYNWRYKNLGNLPHVLNLPEYKRANAGFWFDYQLINVEDFNGVGESEPNPYFYQNLAEAEYVVGVFMYMRTLGYPADKISILTTYNGQKHLIRDVVNKRCANNPVFGRPHKVTTVDKYQGQQNDYILLSLVRTKAVGHLRDVRRLVVAMSRARLGLYIFTRVSLFQNCFELSPSFKILMQRPQVLYLLPHETYPCFRKSEDEPVSEPFIVNDMQHMTHFVYEFYQQKLELAKMQMQKEKMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0S2</accession>
    <name>A0AAV4X0S2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017096">
        <property type="protein sequence ID" value="GIY88707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0S2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10956" checksum="EDAD8CB649CEF05B" modified="2024-11-27" version="1">MKTAVSNRNGSFSFQSEIDALTRRIFPVDRRTRMPNANESVKIDLEAHEPEISVGGMSSTFDIVRSALLFRPLLHLRKTIRDEVGTSRHLGKSESDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X425</accession>
    <name>A0AAV4X425_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_472441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017071">
        <property type="protein sequence ID" value="GIY88499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X425"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="13855" checksum="B6AB0B7DBCA09F38" modified="2024-11-27" version="1">MFNSSVLSPKCNSPCIINFATKPCPSCDCPRIQCSMPKCDSPCRINYSTKPCPSCECPKRQCSVPKCVPPCSINPLPNLVQAALAQRFSVLSLDVNHLVQSIFYTRPCPSCQCPDIPKKKCDPNCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7D7</accession>
    <name>A0AAV4X7D7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_472841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017389">
        <property type="protein sequence ID" value="GIY91206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7D7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="14897" checksum="13A0152B0199967C" modified="2024-11-27" version="1">MALKEEQVIVEEFISSRESGRKHYRGGTVTVVTIANLGDTRYQDTDTTNSLEHKLGGLTPVSPGSRAKATKTQAQNKHGNIRHRFLQDAFCFPDIFPGRSGAAGALTCDSRESDLEIFLPRKHSFGRKTNTLAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7X9</accession>
    <name>A0AAV4X7X9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_795651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017330">
        <property type="protein sequence ID" value="GIY90593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8175" checksum="2BA144D08E85645F" modified="2024-11-27" version="1">MKKTSESLNGTIWSFTLSETTPSEKHVLSFATENERRKQNGSKENNDPFAIKFRNFVRQRHLDLGLASYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAS9</accession>
    <name>A0AAV4XAS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_507881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017510">
        <property type="protein sequence ID" value="GIY92200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12010" checksum="5487744BE347B186" modified="2024-11-27" version="1">MRNAYASCRRFKSVPATLVISNFIKPTLQKRVHPASNEHVLIRNRLHFATLLTATSTNEGTGHRTRLSSLLEIEQRVDLHQYSMAASPPQSKTGPIRDKTNDSAGLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCS1</accession>
    <name>A0AAV4XCS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_488271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017596">
        <property type="protein sequence ID" value="GIY92877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12868" checksum="D8A79CDFBD3764BA" modified="2024-11-27" version="1">MSDLQFRQIVMLCSITHCRPVIQAPELVKKALTECLANILFMSIISSIKRLMTVVVINEGLTINSRCDTPKLQTVLMNSHYLWLLHSAKNGSLAPFSQVACHRLTSPISTSRVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDL2</accession>
    <name>A0AAV4XDL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_237881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000126">
        <property type="protein sequence ID" value="GIY92315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10212" checksum="52C574EDF6246D4D" modified="2024-11-27" version="1">MAVKISSRQKYVARIDGPTGDLHNSYLGMWGSSAKDEIPAPKRTKCHPWHSHLAQRENALYVPVTRNCRLGELIPDFILGRSRAKRQEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFV7</accession>
    <name>A0AAV4XFV7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_158371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000314">
        <property type="protein sequence ID" value="GIY93836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="11920" checksum="C52A9007C4A5C70E" modified="2024-11-27" version="1">MNSCAERKKGLKKKKKEREKKRKMSGFLARPGATDANNGMGKHNRVGKYQKSRSAKAKPMLLITVNKQTERTQVSGGKEETSDFLAEGPGGGEGMAGKKNGTNEYVNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGR4</accession>
    <name>A0AAV4XGR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_754281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000315">
        <property type="protein sequence ID" value="GIY93842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8478" checksum="4803763E21960E60" modified="2024-11-27" version="1">MFVGGHKPLPTLKPTRIFRPFECPQSMAHLCVPRGRNDISNEIHAELHSFQRSMVSPEDPQGPAMIHALGGFTLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK31</accession>
    <name>A0AAV4XK31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017765">
        <property type="protein sequence ID" value="GIY94290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10163" checksum="E7A0E3A060A26D43" modified="2024-11-27" version="1">MLVESKKDSHTLLLNIISKSLGALIRQQDQLVYSCSVEIVSGNINYFLAAVCTLSLKENLLPLSALVERGDSWKGAKSGIMEDESIPLLESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLR4</accession>
    <name>A0AAV4XLR4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_193631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017857">
        <property type="protein sequence ID" value="GIY94994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="21412" checksum="9A6C4498A017C01D" modified="2024-11-27" version="1">MLLVMIVAQPSPRTLGKSLPRFFIFIFFSFQSQPFGERQQGPLFFSSSACHCLPVSALLSSRRRYRGNGPNRKEEEWKQPNRKDCPVKKRKKKKEGIPGRQLPSLITWANECHFFRTRITHQLRAKKSFSFFLFFLFSSFFFRSSGGESAGRSLSLPFRFSATARVNKSRGRTRLVSVYEEQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQK9</accession>
    <name>A0AAV4XQK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_530311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018160">
        <property type="protein sequence ID" value="GIY97461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="364" mass="38788" checksum="782E7567A684D2F5" modified="2024-11-27" version="1">MRIAENSKMGSAKVSKTGFVRYSKMRSAENSKMRSAENSKMGSAKISKTGSEMDIATNSETDVAEDSEMDSATNSETDVAEDSEIDIATNSETDVAEDSEMDIATNSETDVVEDSEIDIATNSETDVVEDSEIDIATNSETDVVEDSEIDIATNSETETDIDVETHGIDLETDNAIYLEPGIEIDLETESAIDLETHGIDLETNNAIYLETDTAIDVETDTAIYLETDNAIYLGTSTVIYLETESAIDLETESAIGLETESAIGLETESAIGLETESAIGLETESAIGLETESAIGLETESAIGLETESAIGLERSNRFESAIGLEAESAIGLEAESAIGLETESAIDLETESATNLEMNTATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRK3</accession>
    <name>A0AAV4XRK3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BCL11B_0</name>
        <name evidence="12" type="ORF">CEXT_18951</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000835">
        <property type="protein sequence ID" value="GIY97795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000106">
        <property type="entry name" value="B-cell lymphoma/leukemia 11A isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051497">
        <property type="entry name" value="Dev/Hematopoietic_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45993">
        <property type="entry name" value="B-CELL LYMPHOMA/LEUKEMIA 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45993:SF6">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="52"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="138"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="369"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="393"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY97795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="434" mass="48311" checksum="7AAB2E17AB2DDE42" modified="2024-11-27" version="1">MSNCEPMQDFYSQRLRVLAGATSPNTSSTPRKLLQPKIGLKETSLKDLKAILNNNKTSPRSSTPPESSFSPPEKSQCNTLNSSASSTTSDHKQSPSAKNRLCEYCGKSFQFKSNLIVHRRSHTGEKPSSATSAIMRLHSGKQAQETHEDTSSKPKSNGDKQTNGDGEYGSDEGDEEDIDIEEEEVEDEEDVNVDCVEDDDCPRENGEGNLVIDHSNDEDDAMVAEDLTKKPLNNANSWKKIGFARIPQYNEAYKQALKESTYRNSIKQERCSSGTDGSASNDATSHHSYDILPYHLERPPRDGSRSAGQSPLNFSSGMLDNLDHTLSMKRMRMEEQWKDKDRDGNLMYAGVWYPRMEQVRLRELYNSDDGATHHHKKSSSESAFNHGDNGRTSLSPLPGPSSALANSLGKSKDHQQRRNDTCEYCGKCSRTAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSL4</accession>
    <name>A0AAV4XSL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_553331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000821">
        <property type="protein sequence ID" value="GIY97697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="310" mass="35430" checksum="ED1302832F880EF0" modified="2024-11-27" version="1">MAWSTIIITYSGCFEFTIVFSSELTYWVQLLQSNQFKKMHTEYDIDASSLNLIAANSSLLNIAANLTDMLQGLIYDQKYTMLDSFTNILVSIGILTFVIYFFTYILFTERESTHRKLLVLENFLGSSDEDITDAIDESLDSKSHDYKRILAGDFSIDMGTERGRMIMLRMDIQCSIVSSRCPVVDTDFDIILEDILYKEVLKIYNMEKNKKSSAATKSKSNTKDIDYKLSDVSVCDPSNSREGQNDTDFDIKIEDILYKELIKIYSIEWNKESSATTKSKSNTKDIDYKLSDVTIGDPRNSREGQNGVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSN3</accession>
    <name>A0AAV4XSN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_186281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018266">
        <property type="protein sequence ID" value="GIY98182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11527" checksum="7744CBFE31AA9F81" modified="2024-11-27" version="1">MNRSNEVLEGKNEGAASSNRIRAAGRKMTAPPRVNDTHSPRSRRFERRQTRVAGGERNPPGRVFLLNDVIPRGEERKVSRGERRVANAAKITERQTHRIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT60</accession>
    <name>A0AAV4XT60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4 gamma 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EIF4G3_1</name>
        <name evidence="4" type="ORF">CEXT_758912</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000855">
        <property type="protein sequence ID" value="GIY97914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049485">
        <property type="entry name" value="eIF4G1-like_eIF4E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF78">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21140">
        <property type="entry name" value="eIF4G1-like_eIF4E-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="2">
        <location>
            <begin position="23"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor eIF4G-like eIF4E-binding" evidence="3">
        <location>
            <begin position="203"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY97914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="336" mass="39078" checksum="968F34A08CEA4FB5" modified="2024-11-27" version="1">MSHLSERKSRSISNIVKELSSEEIYNKATTESSCTSICAKLCNSLESIRVPVSRKTKTHINFGECLLIKCHKEYEKNRIERIKQEEKKKALENLDPDKKSELEIEYEEEEEEIRCKQLGNFRFIGELLKLGILIEPFVERYIKKLSIQNDEKSINCLQRLSSAINNALDEIRLAKNDKEISFEFPTEVPTLSPDTKTYAPKFTYKENQWSPLNPEGKKQYDRDFLLQLQFVPLSQRKPSNLPNLAIIKDKEKKQYDRDFLLQLQSVPLSQRKPSNLPNLAIIKDKCEFSINIKSPVTDTQTSNFKEMLKTKNPLPLVKRSLLFSRFMTSVKQTLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWH7</accession>
    <name>A0AAV4XWH7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_599151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018273">
        <property type="protein sequence ID" value="GIY98250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="9018" checksum="9A2BB36DF9CFA122" modified="2024-11-27" version="1">MTKPILPDQFQKLFIFLSSTEELFNYLPRSIVPSEYGGYLEDYYMTDWLNKAHKQHQRFPKAGEPNFFDISSCSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWY3</accession>
    <name>A0AAV4XWY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_469891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018437">
        <property type="protein sequence ID" value="GIY99581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9730" checksum="AB38784F17B7A5C2" modified="2024-11-27" version="1">MNSNSLKNTKLQEEVKGQKKRINKTIKSLLISSDAASPKEFAGGRSGQKCYHQNSVASRQEDSQDVLDIDNQREENESSLDRSSTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ75</accession>
    <name>A0AAV4XZ75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_613691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001026">
        <property type="protein sequence ID" value="GIY99256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="12021" checksum="7B906076F93237D0" modified="2024-11-27" version="1">MAEVEDKRVLDWRSERKLEDQVKLRGSHPKTENKKGTQFIRDFIPKGLTTQISIFVLTRPTLSFVLVWSPLLRNQWDEKEERTSTSLEQWTSNRSMSNTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2D8</accession>
    <name>A0AAV4Y2D8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_132201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018695">
        <property type="protein sequence ID" value="GIZ01636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2D8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15286" checksum="691CB6336AFFD5AC" modified="2024-11-27" version="1">MGSAVVDSARFCLWTRACVKNVVEAIGGCRIIESRATPATSSRLLLFSGWRCRPSERSFVGPSFSGFTAHHKRDLYPQTLCGMNTPAMDIFVIYCKWALLLIQPDFVYGRELVWCFLDILLSVGKISFWKISVLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2V2</accession>
    <name>A0AAV4Y2V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_726991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018656">
        <property type="protein sequence ID" value="GIZ01335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9764" checksum="7609F96A4D10709C" modified="2024-11-27" version="1">MSNNSAMISLMVLVKVSNGNPPDDILVSSQDWGEVAYLDSLNGVAASPNGTSGKRCLKGAKDYLVLKRVGLCLPVEISGFLGCCRWWFVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y785</accession>
    <name>A0AAV4Y785_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_305641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018925">
        <property type="protein sequence ID" value="GIZ03257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y785"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14071" checksum="149CF3C559DE121C" modified="2024-11-27" version="1">MSSNRNWRGGVKYSELLTATRLRDMLDTPAAIELLTSIEGGIMLEKRTDCDGEGLIVLGKRLTCVDSRSLVVDRLFNCSLALDTKHAIHNATLGSELSEMSFKFGMKDYLKVPISNLHGHAQYINNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8N4</accession>
    <name>A0AAV4Y8N4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase APD1-4 middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">X975_11672</name>
        <name evidence="5" type="ORF">CEXT_132221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018818">
        <property type="protein sequence ID" value="GIZ02499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8N4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032010">
        <property type="entry name" value="APD1-4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032008">
        <property type="entry name" value="APD1-4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39077">
        <property type="entry name" value="DUF4793 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39077:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE APD1-4 MIDDLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16041">
        <property type="entry name" value="APD1-4_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16040">
        <property type="entry name" value="APD1-4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase APD1-4 N-terminal" evidence="3">
        <location>
            <begin position="65"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase APD1-4 middle" evidence="4">
        <location>
            <begin position="212"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ02499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="36247" checksum="C76148B8F418786D" modified="2024-11-27" version="1">MASHALITLGAIVLAIVFFAIPLILKYHVYKPQKKIVVAGDVFKVDGGLSSTWCQGVEFDSKYNFRAFIYDSDPIVDGNEVVRTLSTHHMVLPNKAQEYWGFHLLRGSTVNITSCARLIRADVTVVKGISGLKQCLREHRRAIRDEESSGEDSLSESESDEDTSSISSSQGVVTNKTDILHICTNSILHEELPTSYTCKHPFTKVARRHTLSQYVNETDYYYYIFSSNTYLEILPNEFSIKFSIDRTHYDYSTSSGNCSKDNHCQLRMAMGSQPKVVVQMDGVNGTLRTEKVQVACKPREWIFMIFYGLFLIIIFLCAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE86</accession>
    <name>A0AAV4YE86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_780961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001752">
        <property type="protein sequence ID" value="GIZ04525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12412" checksum="D4F39B8A9FA5FD37" modified="2024-11-27" version="1">MFNERDGYLSFLVNSRVCYRPSIRRFKVFVLGKVIGPCVIFYSSPHTMRWRNPTLRPAGLDLSRSFPYPSYAHLCLKKREGEVWTLVKVTGRIGLRQHSFPARSGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3K3</accession>
    <name>A0AAV4M3K3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_498061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019330">
        <property type="protein sequence ID" value="GIX66651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3K3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="11684" checksum="D9932003FAD75E87" modified="2024-11-27" version="1">MIPSKLQQFKSILLEGDVRRGRDPVLDLVTGPGVGGGRGVVVGGGAAAVVVGGGATAVVVGGGTTAVVVGGGATAVVVGGGGGTAANVNMINEKKLNIRHLLKIQEHKAIFPETFNQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M634</accession>
    <name>A0AAV4M634_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_436451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001911">
        <property type="protein sequence ID" value="GIX67891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M634"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11109" checksum="80F7B8B8F8E3CBA5" modified="2024-11-27" version="1">MDFFFHDDILSLFFDVGSVFVSESIRKWKNSKSIETCQVVESKLNEQLSLHNDKNQLTLVDIMDDVNSTSNNNCKRILLDEIADAKPTSNIVDEKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7F6</accession>
    <name>A0AAV4M7F6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_195031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001917">
        <property type="protein sequence ID" value="GIX68016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7F6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12479" checksum="A48A6D88E0C03626" modified="2024-11-27" version="1">MYENWLRKLETMEESKHFKRGKNSTRIFGRKKENSNISDLYKNSVRLNEFLSELDVKTDIVIVDGDWMMRRKKVVAGVLQTLKHLEKHGPPHQQKSIMYERFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDC9</accession>
    <name>A0AAV4MDC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_293821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002135">
        <property type="protein sequence ID" value="GIX70396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14081" checksum="210D5A17E3C79063" modified="2024-11-27" version="1">MNELRNFSANSGIGSVARRSLSGDSGNSATWRLVPVILCNTPYFDSGRDNRRMGQNSSLLLHTPVPPPLIEKKDSESMASLSNKYLCGPIQTQLPLTNAVISDHPPTEHFFSSSASYNFVQKADNQWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEX2</accession>
    <name>A0AAV4MEX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-centractin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Actr1b</name>
        <name evidence="7" type="ORF">CEXT_458971</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the actin family. ARP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019708">
        <property type="protein sequence ID" value="GIX71004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000188">
        <property type="entry name" value="Actin like 6B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000008">
        <property type="entry name" value="alpha-centractin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX71004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="376" mass="42698" checksum="5C761F3DB48E5B39" modified="2024-11-27" version="1">MEAYDVIINQPVVIDNGSGVIKAGFAGDQVPKCHFPNYIGRPKHVRVMAGALEGDVFVGPKAEEHRGLLTIRYPMEHGIVTDWNDMERIWQYIYSKEQLQTYPEEHPVLLTEAPLNPRRNREKAAEIFFETLNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPNSIMRVDIAGRDVTRHLRTLLRKEGWNFRTTAEFEIVKTIKERACYLASNPQREETMETEKAQYTLPDGSTLDIGPARFRAPEILFRPDHIGEEVEGLHEVLVDAIYKSDLDLRRVLYQNIVLSGGSTLFKGFGDRLLSEVKKIGPKDIKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYDEENMRAIHRKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MK06</accession>
    <name>A0AAV4MK06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_784211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019866">
        <property type="protein sequence ID" value="GIX72668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MK06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11804" checksum="442D1509AFBDCAF3" modified="2024-11-27" version="1">MNSPCKQTIPLQLKQRNAIKGREGSQILSPNLKIAFASVFGLAKSIREEELVFSTDFSQSNDFSLSSSLSLWSENIFPYYLKARCTYWGIRIAELMISIHRLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNZ7</accession>
    <name>A0AAV4MNZ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_525261</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002437">
        <property type="protein sequence ID" value="GIX73654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052116">
        <property type="entry name" value="Centro_Cilium_Assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23170:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23170">
        <property type="entry name" value="NY-REN-58 ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX73654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11733" checksum="641A169B0BC8D313" modified="2024-11-27" version="1">MFSDESLENIILGLEKNKFLLSLNLKGNNIRSFGTQVLGNFFVTIIIYRNLSWNNIGLIGGRTILKSLSKNKTVLLLEISGNDLSSDILEAIQIATSANAQKIYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPC4</accession>
    <name>A0AAV4MPC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_428121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002487">
        <property type="protein sequence ID" value="GIX74244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="23921" checksum="72DF26D3B47025C1" modified="2024-11-27" version="1">MLTECLLQYSIRFRKLGLASLLKNVSCQNALYQQIAEVELCSGVSPDMAWDPWSILTFMVSSTPMPTALFDDKCFKLWQFYGLDPKKKNLRRQASCHVSTLTKALWCQWSIINGLILPRAQISTNYREDSGTCCIAEFRVINPKSVKELICLLQAEWKKIPLAVIQRLVESYAPGGFIHAVIAFVDAYQLLILHKVRFSFLSQVSKCYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVE4</accession>
    <name>A0AAV4MVE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_217867_1</name>
        <name evidence="1" type="ORF">CEXT_111221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002662">
        <property type="protein sequence ID" value="GIX76426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="27593" checksum="F8016314AD178C3B" modified="2024-11-27" version="1">MQMMDSKLSVMEQVMRLDFPGWGRSMSRLFRFILRSPKPFSSTQEEVCTAIATSYDSFLQLAAPYGTRRSSNDAAQSNDEEEREPLDYYIEPSDDILSSDPSDDSFRLLSVICSQIVVEGRTFYQSLSSSASQNGYDITDPQTCQKLYRRNRRRAVRLLATIARCKIPTQELTHNTSEKEVNRTSSIYAQNAEVRVGVIEQDFSFLQKLHEPWGPSENIAPGPDRLTYHHWRSLDQVLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWZ6</accession>
    <name>A0AAV4MWZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_499711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020245">
        <property type="protein sequence ID" value="GIX76295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="38" mass="4346" checksum="EC33E72CC9F6451F" modified="2024-11-27" version="1" fragment="single">IEDINKLICKVLSGWREVRPEVAKDTISLSLIVRHVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYZ9</accession>
    <name>A0AAV4MYZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_582891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002729">
        <property type="protein sequence ID" value="GIX77190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17103" checksum="9E6123B46DFD1A11" modified="2024-11-27" version="1">MVYFQTYTTKTIHGKDSNLKLVVPSELSEVDTNNQAQKNIDQTRVLLDIVLPKNGFKYSLKNSCCTENTLYVRVGICQQRSPESYIADSGQSTIFMGYISLPRCLEFLSPIFRRVLRKGKERREASYIMPSSFPTNPLSPFDYKWRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2V3</accession>
    <name>A0AAV4N2V3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_219451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002825">
        <property type="protein sequence ID" value="GIX78155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2V3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19941">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036084">
        <property type="entry name" value="Ser_inhib-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002919">
        <property type="entry name" value="TIL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01826">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57567">
        <property type="entry name" value="Serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="91"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16697" checksum="5ED2EA3A641E9F53" modified="2024-11-27" version="1">MSLDGAFFYLKQRLFHCLSLRFLTAPKCPQNERYDYCYAKCQKNCSNWDKDIPCNRMCFPGCVCDEYRVRGPDGKCIRTSECRKHEESEEEFRCYKPDGNTPFPGDSRKYIKCTNYIPSVEECPPNQKFDRKELECVDIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4J9</accession>
    <name>A0AAV4N4J9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_512561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002883">
        <property type="protein sequence ID" value="GIX78933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4J9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13163" checksum="0A86F12BA2D3D174" modified="2024-11-27" version="1">MNLVLLEISLYIVCIKLNVDFAKNPSLFSEYHKFMEDYLKLVHMELIPENEIDVPANSSFYLPHHPVPNKSGDKFRVAFDGSAKSSTGVSLSDKLMVGPQLQADLTTILFSLQECTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6M3</accession>
    <name>A0AAV4N6M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_118630_1</name>
        <name evidence="1" type="ORF">CEXT_107991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002954">
        <property type="protein sequence ID" value="GIX79608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="234" mass="27811" checksum="A4F57793A53021F0" modified="2024-11-27" version="1">MFEEDFKGRLEDSEDFLENLKTVAGTAICLRKNSKKKSRHITAFETLKSALMNVTPIVAEDLDVKTMNIPTLSLNTLRSLHKELCKDAGSTEKYHWEPRYMSYDGVTRRNFKQPTKKWVDFHEEDEEYEIDNPEVEEVKMDYDERLWYEKVVQAQIENEEKLLQMPAYTRRINLNKRESTEFNIYDNYLQQIMKCSEINKEDTNCTYRGVDYNVSVTDHIHNFIQPSSKKALYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7V9</accession>
    <name>A0AAV4N7V9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_607481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020623">
        <property type="protein sequence ID" value="GIX80792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7V9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10138" checksum="790A8DC3BDC1994F" modified="2024-11-27" version="1">MCSKEDVDYWSVKELHSRLVPLVSLKRECRSERFCAFDAWSNSAAELKIFPMMPKVRDLVIIALFHINNGGLGNTYPRKRKYLYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJL1</accession>
    <name>A0AAV4NJL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_658021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003469">
        <property type="protein sequence ID" value="GIX84992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="24355" checksum="D49A5B7FEAE598E7" modified="2024-11-27" version="1">MSHRDRFHGYRFDLGSDDFFNESIICDVVYYWMVEKNVPFCSVRSPERTKKNLVRHRAIFPHSGQSRQPKALACSEEQEKRKTRSTKHVARVRSLSQATRAPWVRLTNRSRLINHCLLTETLSLTSRSDRFHGYRFDLGSDDFFNESIICDVLCYWLVEKNVPFVRMKMFEVQKEQNLGQAPCHFFPHPLPFLANVECRISDRHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTW8</accession>
    <name>A0AAV4NTW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_679581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021233">
        <property type="protein sequence ID" value="GIX87396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13683" checksum="B9E53143526253FB" modified="2024-11-27" version="1">MPPAGFEPEAYDTKGARELTNWPSGHQGKEEVTWLDSRGSDRQAVVNFPKQPICQYPLPLINSTITHFRSLCNAKNANKKSIDEEGLKGRGNFSDLKEFFQWNGDPEESKNGSLSSLVAHYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVJ4</accession>
    <name>A0AAV4NVJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serpin B3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SERPINB3</name>
        <name evidence="5" type="ORF">CEXT_112581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021265">
        <property type="protein sequence ID" value="GIX87770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF372">
        <property type="entry name" value="ACCESSORY GLAND PROTEIN ACP76A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Serpin" evidence="4">
        <location>
            <begin position="96"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX87770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="467" mass="54222" checksum="211BA5B4687EA2C8" modified="2024-11-27" version="1">MTLERQTKPNLVPIRWTFDMISISFVIYRIKLVHKFNALSIQPFSEELLKMYFRKFLISTLLIGVATGHMPNTELSGDSVHFSLHKLSEAVNTFGFNLFSSMRRIGTSSNVCLCPVSLVNVLSILHYGARGETEKELSKVLFFNDYNLTSTEAAEAFYKLQTELLVSSNHNHYFFNASATILIDEHSNVLQSFQRTVEVLFQIPLTVVNFKDSAQRTVESINTWVAERTRIKILEIIDKIDESADMIVLNAAYFKGRWVHTFSPSDTTYKFFYNYGSRSHLKKFSIFRKVPMMSLTKRLRCYFTHDYSILEIPIRGRNLSMVIYLPSTKEGLFNVENILFPEVFWDNMNLLHRRQVKVTLPRFNFEFHGNLTENLLHLGAKTLFDSHSVNLSGMMSRKRVIFRDVQHKAFLSVSEGGIDAMPPRNSISHKIFAEKYDILFEVDHPFIFFIYDKRLSMILFMGHITEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P294</accession>
    <name>A0AAV4P294_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_703931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021530">
        <property type="protein sequence ID" value="GIX90769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P294"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8205" checksum="F5A4B5447720CB8A" modified="2024-11-27" version="1">MEWSDALLKKRVNREARSQPYVTGGMITLKPMIAGMLSLDESSYQLLRINDEKGWERPNMSNLASLCDSEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P605</accession>
    <name>A0AAV4P605_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004131">
        <property type="protein sequence ID" value="GIX92476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P605"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13816" checksum="1E5EC1BE7DD7E160" modified="2024-11-27" version="1">MYLLEEVALHSQNHYLKNGQFIEKFVLIPKPFKAYAINPLRSFAQFLSGNTSTSSTIVRQKLASHLKQEALDLLTPISLLKEINSILRAFPKFFEVFPVMKRTSNNLDDSAYSCKPLLAAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA26</accession>
    <name>A0AAV4PA26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_382971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004313">
        <property type="protein sequence ID" value="GIX93931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14758" checksum="E0A900F842E852FD" modified="2024-11-27" version="1">MLSRQTAERQVLGQVLTMTTQSIISFSEVLSTKPAAQENALGSLHTFLQPGSALAVEGVFAGLLSEQRGEGFSTKLHNAIFLIFVETGETLCFGVAEEISKRWCYKQGHHVFVPKTRNALITSLLIYDPRYLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAY1</accession>
    <name>A0AAV4PAY1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_146051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004349">
        <property type="protein sequence ID" value="GIX94224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAY1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10011" checksum="86DD380BAC8CDDF5" modified="2024-11-27" version="1">MVPPMEQKGQSGVTVMPILGRCSWRWSCPLTILKLAAKNLPGEVYWNRIVKQAFSDLAPGSFHLSFYARCLSQAVGYMKTLWKTATLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PB99</accession>
    <name>A0AAV4PB99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagelliform spidroin 1A variant 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Flag1A2</name>
        <name evidence="4" type="ORF">CEXT_900171</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021723">
        <property type="protein sequence ID" value="GIX92966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PB99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031913">
        <property type="entry name" value="Spidroin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038243">
        <property type="entry name" value="Spidroin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16763">
        <property type="entry name" value="Spidroin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043764003" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="domain" description="Spidroin N-terminal" evidence="3">
        <location>
            <begin position="27"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="813"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="901"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="956"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="924"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1105"/>
            <end position="1117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX92966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1211" mass="103925" checksum="3B7D3D716FB8F5A9" modified="2024-11-27" version="1">MTCFTTAVIFLFLAQYAREFSFSPYTPFSNPNTAESFARSFVANIVNSGEFGSQAAEDFDDIIQSLMQAQNMHKGRRDTNAKAKAMQMAYASSIAELAIAESGGADLQRRTNTITNCLRNALRSTTGSVNEEFVREIQDLINLFSMSFNEIETYNAPGQYNQSVSSGGQGGTPKVVETVSVSIGGQGGGGPGGPGGPGGPGGSGGPGAAGGVGGISGPGGAGPSGGGAGGVTVVDNLSVNVGGAGAGGAGTGGAGGSLGGFEGFGGPGGPGGPGGPGGPGGSGPGGMAGPGAGGPSGGAGGSGPITVSGTLSVGGSGPGGAGPGAGDRYGSGGAGGGSVGGAGVFGGPGGTGGPGGPGGLGGPGAGGVGPGTGGTSGPGGGSGPVTDTDNVSVTVGGSGGSGGSGAGGALGSGGGFGGFGGAGGPGGPTGPGGPGASGAPGGPGGPGGYYGPGAGGAGGMLGSGAGGVSGGPGGLGGSGDFGGPGGVGGLGGMGGVGPGGSGIMYGPGAGGAGGGFGSGAGGAAGGQGGFGGAGGPGGPGRPGGPGAAGGVGGISGPGGAGPSGGGAGGVTVVDNLSVNIGGAGAGAVPTGDAGGSLGGLLYAGGAGGSTGLTTGDQGNPGGPGGPGGPGSSGAAGGMTGPGAGGSGPITISGTLSVGGAGPGGGGPGAGSGRYGSGGSGGGAGGFRGPGGPCGPGGPGGPGGLGGAGAGGVGPGTGGASCPGGSVAVGGSGGSGGSGAGGALGSGGGSGGSGAGGALGSGGGFGGFGGAGGPGGFGYGTGGSTEVMEGFGGAGGPGGGFGYGTGGSTGGHGGFAGAGGPGGPGGPGGPGVAGGVGGISGPGGAGPSGRGAGGVTVVDNLSVNVGGAGAGGAGAGGAGTSGAGGSLGGLGGFGGLGGLEVSGGPGGLGGPGRPGGPEGSIAAGGMTGAGARGPSGGAGGSGPITISVTLSVGGAGAGGSGPGAGSRYGSSGAGGGSVGRAGGFGDQVGQVNLVGRRSGWSWWSRNGGVGPRTGGASGPGGGSGPVIVTDIVSVTVGDSGGSGGPGAGGALGSGGGFGVFGGAGGPGGPGGPGGPGGSGIVGGAPSPSGGSSGPETVSDNISITVGSPPSSAGSAGPAFPGKPIVSRLPSLVNGMLSSMQSNGFNYQNFGNLLSRYSSGSGTCNNNDLNLLMEALQAALHCLSYPGPASVPSMPPPSSTSAYTQSIRRVFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCY9</accession>
    <name>A0AAV4PCY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_418961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004294">
        <property type="protein sequence ID" value="GIX93764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12761" checksum="1C22FFD2C806FF60" modified="2024-11-27" version="1">MVRYRQTGGCTCKLPQVPISPSRKNDSLKKQILNIREISFVKFPIVFKRPSRDSLSLYNSPAVFLLLAPYISLFLTGFKKSFNEQACLIRLPNFVPFFPSIDKGGKNARVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGN7</accession>
    <name>A0AAV4PGN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_9001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004632">
        <property type="protein sequence ID" value="GIX96325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17394" checksum="3675DCAF2E235258" modified="2024-11-27" version="1">MQSHRSSLYLESTAKRSESLTSSKLGFIPVRLNYSVETWKTLKITENKIKRSPEAPDSNCPPKMTLVLKGSSTHCDRSPYLESTTKLSKSLTSSKLGFIPVRLNYSVGILSSLRTKNPSDAINTVPLSALFPFIEEWSLDKWVNWFSAGLRRKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHH4</accession>
    <name>A0AAV4PHH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Netrin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NTN1</name>
        <name evidence="5" type="ORF">CEXT_670451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004568">
        <property type="protein sequence ID" value="GIX95843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001134">
        <property type="entry name" value="Netrin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018933">
        <property type="entry name" value="Netrin_module_non-TIMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008993">
        <property type="entry name" value="TIMP-like_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01759">
        <property type="entry name" value="NTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50242">
        <property type="entry name" value="TIMP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50189">
        <property type="entry name" value="NTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="NTR" evidence="4">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX95843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="10029" checksum="3439D07F4741782B" modified="2024-11-27" version="1">MQVFKQGSAKVHRGTQFLWVSVSHLACKCPKIKVKQTYLILSKDVRQPERPGLTADDRSIVIEWKDDWARRMRRYQRRQRKGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PIX7</accession>
    <name>A0AAV4PIX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_239161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004724">
        <property type="protein sequence ID" value="GIX96988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PIX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8915" checksum="A56DD5D841F97458" modified="2024-11-27" version="1">MGRNNTRFCWTRMIKDRGSQTPLSQDRTNPLGHLSPASRASNGSLPANILNPIDQIALCQNLNCPLLKFDSLEFKCLSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPI6</accession>
    <name>A0AAV4PPI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adipocyte plasma membrane-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">apmap</name>
        <name evidence="6" type="ORF">CEXT_420651</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the strictosidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004855">
        <property type="protein sequence ID" value="GIX98076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018119">
        <property type="entry name" value="Strictosidine_synth_cons-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10426:SF88">
        <property type="entry name" value="ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10426">
        <property type="entry name" value="STRICTOSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20067">
        <property type="entry name" value="SSL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03088">
        <property type="entry name" value="Str_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043977475" evidence="4">
        <location>
            <begin position="17"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Strictosidine synthase conserved region" evidence="5">
        <location>
            <begin position="146"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX98076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="359" mass="40208" checksum="57B78031A0296A88" modified="2024-11-27" version="1">MGWNLVIVILAVGVYCLTSDFFKKVNPVSYRVSLPEKFSGGLVPNELLDKAEHLHADALHWAESFAEYKGKLYTGLGDGRIVRITNKEVVPILRTGETCEGQHEEHICGRPLGLTFNKAGQLFVADAYLGLLSIDINTGKKSTFCHQKLYIIEHDTSGRLLKYNLKTKEVSVVLKDLAFANGVVLTHDGNALLVAEGSNNKVFKYQIAGETKGYLDFPLVLPGEPDNIKRSKNGNYWISVATGRTLDNPSILDRISDKPFWRSLFLHIHKLSTLPICSIMRLIPHKKVKEIGFELQNARIIADVAINYGLVIEFDDSGKIIRSFHSPTGKVSHLSEAFEHNGYLYLGSWRNKYIGRLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV85</accession>
    <name>A0AAV4PV85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_465841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005141">
        <property type="protein sequence ID" value="GIY00072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13970" checksum="CE17DC5DC459E7A5" modified="2024-11-27" version="1">MVYKLVRFYTRVQKNNSDRRRKTVDQFKYFHATNCRSDYFNHRYTLYPSERAASGKTITTRPAPIRATPFQCVCECQVHNHLLPSRRVQDNWSQNRGQVIAVDIHLQLDGRGERRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q061</accession>
    <name>A0AAV4Q061_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_113991_1</name>
        <name evidence="1" type="ORF">CEXT_661341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005504">
        <property type="protein sequence ID" value="GIY02805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q061"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10056" checksum="1FFAB42D575C672B" modified="2024-11-27" version="1" fragment="single">EPDILICGNCKEVFPGIHKLIEHKKQSCKLRFTCRCQHTSSPPGAPAMPVCAQCQSRQNTWWDLVQHFQVAHNALLYVKEDELTVSPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0H5</accession>
    <name>A0AAV4Q0H5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neuropeptide CCHamide-1 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CCHa1-R_1</name>
        <name evidence="2" type="ORF">CEXT_526561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005401">
        <property type="protein sequence ID" value="GIY02031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0H5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9785" checksum="1774A5258D57B376" modified="2024-11-27" version="1">MAHHEETFPVEENLCDHCPSALPLVNFSNMVLTINDQLDNNETWNFTEYVPYEQRLETYVVPAVFALVFIVGLLGNGTLICIFLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q414</accession>
    <name>A0AAV4Q414_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Fumarylacetoacetase</fullName>
            <ecNumber evidence="4 15">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">FAH</name>
        <name evidence="17" type="ORF">CEXT_278201</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="4 15"/>
    <dbReference type="EMBL" id="BPLR01005741">
        <property type="protein sequence ID" value="GIY04688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q414"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902000">
        <property type="term" value="P:homogentisate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000004">
        <property type="entry name" value="Fumarylacetoacetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="16">
        <location>
            <begin position="7"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY04688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="300" mass="33512" checksum="348A7B31B99DB31D" modified="2024-11-27" version="1">MKLGDYTDFYSSEEHATNCGIMFRGKDNALLPNWKYLPVGYHGRASSIVVSGTPIRRPNGQTRPDDSMPPQFGPSKLMDFELEMAFFVGCPSKLGEPISIEKAQDHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSLGTTISPWIVPMEALEPFLCENVPQDPTPFPYLKHSEPYNFDIHLEVSLLPENAKEATVISKSNFKYMYWTMKQQLTHHTITGCNMNSGDLLASGTISGKTPDSYGSLLELSWKGTKDIPLSDGQTRRFLKDGDEVTLTGYCQGDDYLVGFGTCTGKILKALQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4N6</accession>
    <name>A0AAV4Q4N6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_110292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005770">
        <property type="protein sequence ID" value="GIY04913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="431" mass="50360" checksum="427B9E812026110C" modified="2024-11-27" version="1">MLLSSGKLRKLKLCFPVFFTDICIVLPQMLTEKGCINIKVLELDQNFENDESKWLEKLLQKLPLLESLSVRTLFNPQALMNCKRLKQVEIIPMFFITEESDFLSEAADTLSHLEDLEEFDIFKYTRKSSNFLKVVKLLNNHDKLTSLRFTDSSRAAHHIMANNTRGRHPRYGLRKCSWTIGIGSFEDITALKFSFLQRIISSVLLFPFVEELEILVLCEDCFEYLKRLKHLRSMKMKFHIDSTYQWNFSFLSGIGQQLRHLCIVSHQDVPVNAISKYCFNLEYLKIIGNATLCDSIKSSYNFRMLKRLEISLIDANSLLYVFQNVRNLKELQFHNAAVFDDLRLQEILNRDPLAFNHLDKVFVRDCMLSTEGFRIFLKHAVNLTTAYIKSSHFSVGVQTDFSDVIKELERDVIHNYFAVGHYFKNTSYFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5P5</accession>
    <name>A0AAV4Q5P5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_522481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005749">
        <property type="protein sequence ID" value="GIY04770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5P5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11062" checksum="71E481D53C5E5173" modified="2024-11-27" version="1">MVPHSTFTSGDEKQRFVFLLGSFATVLVNNLAADLRGRTLRMFKCFFIFLLGEFQLCLENVSTFAAKSRKYGLGLFPPTALNSALQRKVEENSLGLLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q831</accession>
    <name>A0AAV4Q831_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_387701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005849">
        <property type="protein sequence ID" value="GIY05482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q831"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12420" checksum="1B837FBD7946D10A" modified="2024-11-27" version="1">MVKCPKGMKVNVPLINLSLLSTGNFLGQSFQFQTQNNPFLVILLHKKKGKSLFCREKKKPLQNQRSGLGLPINRFSKQTIIHRRNKNKENRENKRNIGRNRKYSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAQ6</accession>
    <name>A0AAV4QAQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_390451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005798">
        <property type="protein sequence ID" value="GIY05075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12508" checksum="9730842375400D7A" modified="2024-11-27" version="1">MGSPPNKIATRHVSRELDANVAMRSVKPGPLTPLCSRGSKSTVSIAFPLPHWFCDSSEESFKSFRRNQRALERVIHATNAFLSKRVYYSQRNCSKFKFMTKEFSSYFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIN4</accession>
    <name>A0AAV4QIN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_40551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006179">
        <property type="protein sequence ID" value="GIY07946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="18" mass="2180" checksum="51D0C5318AA3A83B" modified="2024-11-27" version="1" fragment="single">MQLFGKNRESESWNLVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMC2</accession>
    <name>A0AAV4QMC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_585201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006345">
        <property type="protein sequence ID" value="GIY09236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11286" checksum="E76F982430003EDE" modified="2024-11-27" version="1">MSTWTFSPRLSGERNKEKKLGNFSRKKKGTILRMTYKTGFGNPFRGWGGGCSTSYHFECFESRGSDPSREGFVQRRWKRERSEVIDTGLQCILNFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNI7</accession>
    <name>A0AAV4QNI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intraflagellar transport protein 74 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IFT74</name>
        <name evidence="3" type="ORF">CEXT_198171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006535">
        <property type="protein sequence ID" value="GIY10501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029602">
        <property type="entry name" value="IFT74"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31432">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31432:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="197"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY10501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="260" mass="29414" checksum="A4A066326762E8BC" modified="2024-11-27" version="1">MDGRPPTSAGNRPGSGLRPMSSARQPTSLALPSRSGIPGTASRLITASSNRPGTRSGFAQGVGVLSHINVVDRPMSQQGLVTPKTGVRTPRRQVQDKSYFMGLLRSKVNELTTEISRITKEIDLLSKEQSTYLTYEKRAEVQALELKNFQGQLADYNLFVDKLNTDVEMSDVQQEYRELKKMIYFVFVQNENEAVSIDSLFEQRQEREAQLSQLEAEISQERYVAENLTSTMSPELRQQYNELKKTDNNLQRSLEKFSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNL1</accession>
    <name>A0AAV4QNL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_30481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006592">
        <property type="protein sequence ID" value="GIY11010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="236" mass="26603" checksum="AE70CF1853D0085E" modified="2024-11-27" version="1">MKSIRTLKRYNVDYRSQIAEKDDLLGKMVEHIKHIWSTLINVCGKLGNAVIKNIISIDSPPPSVSSNDEVSIKINNFVDSNENNHSVTNRIKTTKNQMNLNCNSTFDSLNSKLEINISNNRGDSFRVKKLAINEIQNESLTKSNKQNQCNQTKPNVENTLDMINIAKITDLLPNVSMPVLELSSDSDEELITVPELDMLESNALPNSILVEPVLQETITNEKKYQLAKTNMYLTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPU5</accession>
    <name>A0AAV4QPU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_8771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006686">
        <property type="protein sequence ID" value="GIY11713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8715" checksum="27C403956A6129FD" modified="2024-11-27" version="1">MHVTISQIDVLFIYRDERDGIFFVVIGKDNSLYEREIEEFSDVDIELNPDFGDDLDWEELGEKTLLKQNLRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVY6</accession>
    <name>A0AAV4QVY6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_94831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006874">
        <property type="protein sequence ID" value="GIY12974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13131" checksum="5037784A47DDB651" modified="2024-11-27" version="1">MPSCRLIDMPSCRLIGMPSCRLIGKCFDIVYGTTISSCGKNESPKRIIRKQVLTLEEVLTLVYQIETCLNSMSLVPMSSYPEELKSSHIWKFLIVTALHAIPELNLISDRITLTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QX02</accession>
    <name>A0AAV4QX02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_229041_1</name>
        <name evidence="2" type="ORF">CEXT_407521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006857">
        <property type="protein sequence ID" value="GIY12831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QX02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="452" mass="50502" checksum="19AA85281E99439D" modified="2024-11-27" version="1">MQYGSLHALRIVVSGKLLGIHISTEDDLMNFRLPYSTDSNFQGDLIVVVVIGRNKISLIFVSVKSKQPRDIANPFFSPLETKSVCVVAPVHSDSELFNREEERSIWVNVELKKSFNALLRFMDITSTINETIVLMAQSHLIINQDLKPVLSAQQQLQQHQQQLHMQQQMQARFYNSQSHLQHMPTSQTSLNFQYAGPTSSINSNINQRSSTTAQTNPSQRQQFYMTRPPPEYQASIEPNNTSISSLKSVLSQNAQMHNSINVCNDQSSRNMELRNFNASKSYSSMMPTSQILSNQHVSHILTYHLFQLLILVPLNFKYQISNNKSYSDDILSNSTTSRPFAGLSQNSSAISMSKSLQDSISMSNASVLTGKSYPSNASILNPLSVSLPKPFVDPSLNNMSTSKSYQRRMANSNLTASQPYAVSSGTLLGQSQMMPVTTVTSTYTSSRGTSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QY55</accession>
    <name>A0AAV4QY55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_733411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007002">
        <property type="protein sequence ID" value="GIY13786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QY55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9535" checksum="4F2113A1AF6CDB87" modified="2024-11-27" version="1">MAYEFYCYNRPSKFQSSPNMTPDTNETFLAGHCRVYGRASLIIAAVKLKIHFRLYRLSTPALRIPHTKKSKPEKYQVRLGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1P3</accession>
    <name>A0AAV4R1P3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007176">
        <property type="protein sequence ID" value="GIY14986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1P3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10264" checksum="E1CDA69790DE7761" modified="2024-11-27" version="1">MCINIKKTAFIYSINTYAQHGQDHSSLSSDIRVKINDGVPMTGMRTFQRRLEGIFDRRFRATNNENIRRNHSFSRSTEETLLVALTWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R398</accession>
    <name>A0AAV4R398_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase-like protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">METTL9</name>
        <name evidence="1" type="ORF">CEXT_783721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007158">
        <property type="protein sequence ID" value="GIY14882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R398"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106370">
        <property type="term" value="F:protein-L-histidine N-pros-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007884">
        <property type="entry name" value="METL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890">
        <property type="entry name" value="DREV PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890:SF0">
        <property type="entry name" value="PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05219">
        <property type="entry name" value="DREV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="23675" checksum="279499652F0F55A6" modified="2024-11-27" version="1">MFVFSNAQFENIVAPFSHLKEQWMTCGNLLDLGAGDGKVTEVMARHFRNTYATEISGVMRNILTAKSYRLLDVDKWANVDEGPRYFDLISCLNLLDRCDRPITLLQQIRNKLNPDTGILVLAVVLPLHQYVESGSKYNLPEEKIQVKGRTFEEQVSDLTTSLFRPQGFQLLRWTRLPYLCEGDLDQAFYWLNDVLFVLKVSDTCDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RR62</accession>
    <name>A0AAV4RR62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_294931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008329">
        <property type="protein sequence ID" value="GIY23887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RR62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="11948" checksum="61E0A2DC2BF90DCC" modified="2024-11-27" version="1">MRASSRVTKDSIPVSGRVYLASLSIQISLSENAIMEFLPLVDAPTLTESLPRLHEASSHSLLCDMGITQSGLMSLSGLVYAGAKLFLRGDVSPHYLLICVRGNALRVFSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1H1</accession>
    <name>A0AAV4S1H1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Probable very-long-chain enoyl-CoA reductase art-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">art-1</name>
        <name evidence="1" type="ORF">CEXT_60601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008763">
        <property type="protein sequence ID" value="GIY27031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1H1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10850" checksum="4122C14263B5337C" modified="2024-11-27" version="1">MFILLQKKKLDPCRQALRLDPRGKFLSDNLALESIEFKGQNKQLYLKDLGPQIGWKTVFLFEYAGPLALYVATYLRPAFLYGADATKAINPVVSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4X8</accession>
    <name>A0AAV4S4X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_9371_1</name>
        <name evidence="2" type="ORF">CEXT_275821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008851">
        <property type="protein sequence ID" value="GIY27782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="475" mass="54018" checksum="4E9086F79E5D8B4D" modified="2024-11-27" version="1">MRGGKEKKKEKKLFRTETQTDIHHLRIIPLTAISSNQVRGGKFLDLANYRQPILLIAHHHKHTWNERMLSYLSNRGAQRRLYHYTVSSFLPGHQLIWAWSSDLRYLPSGGFIPWTCQHSLKKFDMTAQMQSTPRHLAFISLALGFLVIWTAVLAGVLVSRTLKDEASAKETTKVFNTHEDVGKVLFALGHELVSTVDWMLSTSDKTKVDNIVVTWKITNGMLSKIKEETSERWVPSVISMLDTLQERLTVFRETVSDIKSNPLSTVKFYLDLSDWVLQRCFLLDYAGQHLPVPSLPYTLFVRGMAQRFGELALGTIYVKSDMPINKSEFFKLRTGSEELMEASFHFTPRARTKWMELQEQEPGVQKVMEAVVEDILSGSSLRGQKELAINYLDGVKEQIAMLLLTKEVLNASLSSWVERLSQRSHNTLAFHMSISIVAVVAVILCLIVTSCSCSYLSKGQPDVEKHNSQMPLQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S834</accession>
    <name>A0AAV4S834_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty-acid amide hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FAAH2</name>
        <name evidence="1" type="ORF">CEXT_197381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009041">
        <property type="protein sequence ID" value="GIY29241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S834"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052739">
        <property type="entry name" value="FAAH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372:SF4">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="230" mass="26053" checksum="03D940E86BF105E1" modified="2024-11-27" version="1">MEDDGGYPFRTPVSREIKKALRKAVGHFDGICETKPQKIFQEKLQDAVETWVCVIESLNDQQLGNEIVGYQKKLNFSKEVLKSMAGKSKHTFPVICLAILDRYIRNFDVKLAEPFFRLRDELLEEFNELLGEDGIFLYPTYPDTAPYHMEMLFRPFNIGYSVIFNILGLPVTQCPMGLGDKGLPLGIQIVGALNQDRITMAAALELERVFGGWVSPCDIRKSSITLTEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9I7</accession>
    <name>A0AAV4S9I7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_447001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009049">
        <property type="protein sequence ID" value="GIY29291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9I7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16201" checksum="7B9739AB6412F141" modified="2024-11-27" version="1">MLEMPRFPAQSFCAVVNWYNLKLEPYYHKHLFNDLVKYKSEFSESRACVHRKQDCRRSNNECHRSSCAAREHTGLTGEALSTASGKQGNTTGGSCTECLFSLLIHRGDSANNTVNLTTHGVTPVAEPPVSYLDLASTSMALQAYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDH8</accession>
    <name>A0AAV4SDH8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_715041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009389">
        <property type="protein sequence ID" value="GIY31537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDH8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12037" checksum="54968E9621A9735F" modified="2024-11-27" version="1">MLRNTFDFSDISPATLRNSLYDQSNVILMDYGFTNPFFYSNYAVQPITDYLETLTTPMMLQIYANSMGKLLDYLGILRDDNAAQLALEYASKIEETTKNKLGRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGG5</accession>
    <name>A0AAV4SGG5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_303501</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009298">
        <property type="protein sequence ID" value="GIY30948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="293"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY30948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="353" mass="40021" checksum="B8D299F0918A0B35" modified="2024-11-27" version="1">MEQGLKSLSCLMEICKNLNSFLQKEVSPFETSVSDIDDEPSKTLLTYMSITFASSKYFLHNIQKYNLSFQVTSFVATNSKIVSSVEKGETTITKNYGVEKQLIKELEEEIEDDEEIHKCLENALREKVKGLSSTANEFLKVFIQNLVTKEKEYYLSNYKISCNLENIMKDVTESSKTVESCKLATTNVKARECYSEERIHETSRNSEARRIMRNVASDPDIIENEIVVRKIKRLPSTPGGIRLCETRTVVSKDDELFREMPSTSTASLIDDQKSKGGRKENSLNGSDYCYREIYVYLAVAERDYEAEGEDELSFKEGDIIEVLSDKGTENLTGWIEGTLRGGGTGMFCTDYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SK54</accession>
    <name>A0AAV4SK54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_322361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009657">
        <property type="protein sequence ID" value="GIY33571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SK54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24298" checksum="323DF0DB71DEA182" modified="2024-11-27" version="1">MDLDVLMGERTQPAIGGNSRRGTLSLLQARAPTACRFRRALRGNLSIKYISGRKWMGDAVGNPVSMTTRGRRRGGRHEFCVCRPLGMQMTWEPKKRITAWERMKERGRGFRKESSEYGDKDEEDDMLYNKLIIRDNCEQTKSLVPTQLGQSIPKRNIHATRLCFAYGGIRKVCHMKNLQHFLQSINAERGEQTNNPFESTIEREMSKIFVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXT8</accession>
    <name>A0AAV4SXT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">28 kDa inner dynein arm light chain, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IDA4</name>
        <name evidence="7" type="ORF">CEXT_691121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the inner dynein arm light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010164">
        <property type="protein sequence ID" value="GIY37352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019347">
        <property type="entry name" value="Axonemal_dynein_light_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183:SF0">
        <property type="entry name" value="AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183">
        <property type="entry name" value="AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10211">
        <property type="entry name" value="Ax_dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY37352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="331" mass="38326" checksum="81B06AD901E41620" modified="2024-11-27" version="1">MQQQGHIFSCDGSHAKFRRNEVESCPRMSPSCILSSCPIFEEFGYILYLVAEKFPINLNMATSLSEMIAAPALSLVKYANAIFGNNKRNRWQSSDSRLPNIRDKPSSAKSSRQDSKNKDPQVAEILDAILPPREFEDDGKLWIQPVSRTPATRLDVVNLAEKLDARLIERNAREIGICPIRRELYDQCFDELIRQETLNCMERGLLFVRIRDELRMSLAAYENLYDSGVAFGIRKALLSEKRKLDIVERLDFLTAENEDLRKQLKLQEARHALLQRDWEQHTAVESKKLGDKIELLERANSQLKMYPEYPYSLYSRTLTQYTQRTCTQEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXV6</accession>
    <name>A0AAV4SXV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_341361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010046">
        <property type="protein sequence ID" value="GIY36423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17331" checksum="4B89E79DB7AC2DB0" modified="2024-11-27" version="1">MQVYAIKFDPIKMPGLCQVCNLPTRSHEDNADILKCHRTEFAKCYVWLPNPKGSQTQEGKNSRKDVSSAVSLKTTSGTLECGLPIWSRSHTSPKIPKAFFRLHCGSSSENPLHYAFIFPQMVLSGRFLAHSEMSFKRSCQMLRGYKIAISACPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDC6</accession>
    <name>A0AAV4TDC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_512321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010971">
        <property type="protein sequence ID" value="GIY43387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7787" checksum="10CF5F8FE65AC61A" modified="2024-11-27" version="1">MPDTAKGSKVGGKNPGLAVILRTANAFVVLVQVAKFNEFLVFFSNRALYKFTISQNFVTNWCRVVVWYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEX5</accession>
    <name>A0AAV4TEX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_395001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010858">
        <property type="protein sequence ID" value="GIY42513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13347" checksum="2C90611B75CC3A62" modified="2024-11-27" version="1">MDISVLAQLNAHHRNQPFLLAQLNVHCRNQSFPLALLNAHNRNQSFLFAQLNAHHRDQCFLLAQLNAHHGNQTFLLSQLNVHCRNQSFLLVQLNAHHRDQCFLLAQLNAHHRKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKT7</accession>
    <name>A0AAV4TKT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Pxd</name>
        <name evidence="2" type="ORF">CEXT_93551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011358">
        <property type="protein sequence ID" value="GIY46046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF134">
        <property type="entry name" value="LD42267P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="388" mass="44718" checksum="C784498696B0AD17" modified="2024-11-27" version="1" fragment="single">MGDIILMANIVVHKKFEQRGVKKYLLGAVLLGSIAVSQSQVTTWNVRNNQVPHANAYYHSGGERDVPVLPHMREGKETKTYKQYEILDPREIDATRQEITKCSDQYVHCYYAEYNKYRTIDGTCNNIKNPSWGKADNCLRRVLPFDYADKISFPRESCTGNPLPNPRLVSNVFHKEIKPKHDDLTTHFMEWGQMLAHDLSLNDIFRDYSYGTQEGIQCCNNGPHYSDKCMSIPVPPNDPFYSKFGQTCINFVRTVPCRHCSSGVVLIQWNEILFRPLANEFIELQNTAYHDLSLVYGSIEEEAQKLRSGVKGMLDVEYNRKSGLMPPTVPVEELCISPDREKAAIRQPNQNPFLLTVHTYLLRHHNFICQELSEVNPHWDDEKLYQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TPZ0</accession>
    <name>A0AAV4TPZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_722401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011485">
        <property type="protein sequence ID" value="GIY46812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TPZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13667" checksum="3830FAEC11D1CC7D" modified="2024-11-27" version="1">MLCYRRGKLTPSSFLLSLPSFEQNINNFFDRLWKRGSLGKRGGNKTIPSIFGGERGIQTTISTGLLSRTAMTAINGPRDVLTLRAFHNFDCKVAWRFVPVGWLFWLSIVIAILFDRTVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRW8</accession>
    <name>A0AAV4TRW8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fibrinogen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Fcn2</name>
        <name evidence="2" type="ORF">CEXT_675221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011586">
        <property type="protein sequence ID" value="GIY47502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10767" checksum="D448456E730CE310" modified="2024-11-27" version="1">MDVYCDMDTDGGGWTQSLKCLHRFLDNVMYSLIVGDFYNDWESYKAGFGNMTRDFWLGNDNIYALSNQGACEIRFDIKDTKETTDMQSTKAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8C6</accession>
    <name>A0AAV4U8C6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cuticle protein 16.8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_176945_1</name>
        <name evidence="2" type="ORF">CEXT_305141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012449">
        <property type="protein sequence ID" value="GIY53987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8C6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="15380" checksum="E2AFFD0DC7603861" modified="2024-11-27" version="1">MPLNPYKFGYSIKDHHSEQHREESGNGAGAVVGNYGFTDDRGIARQVNYVADHAGFRAQVKTNEPGTANQNPAAVQVISNTPLCCRCIYVPVGPAVVGHGPVVGLRAGYGYGSLDGNVRFGLASYQQELAGGAIRGYDGQLVPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8S7</accession>
    <name>A0AAV4U8S7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Tmem165</name>
        <name evidence="7" type="ORF">CEXT_466911</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012478">
        <property type="protein sequence ID" value="GIY54171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8S7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043090879" description="GDT1 family protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY54171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="28733" checksum="F7C715134A4E5DC4" modified="2024-11-27" version="1">MWSLHVLLLSSLCVWKAGAAIDTLAPVNDVLPVSQEEVNNGTQLVYSDGSFVSGVLSALTVTAVSEVGDKTFFIALVLALTHSHVIVYAGAITALALMTVLSASLGLVFSFLSALWVHYLSALLFLLFGLKMLREGFTMSSNAAKEEFEEVQKTVETKITHTKASLDLESGSSRVSVRWVFVEAFTMTFVSEWGDRSQIATVILAAKHSVFGVVLGSILGHAACTLMAVMGGKLIANWISVKTVTFMGGLLFLAFAFSSLVGALNDSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAZ4</accession>
    <name>A0AAV4UAZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_677891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012575">
        <property type="protein sequence ID" value="GIY54928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9607" checksum="ACACD5F9A9DA544C" modified="2024-11-27" version="1">MKACRSFPSQGHFRTNSQIHFRTNSQTFYYWSNHRGEGEREERGNTPRHPSAPYLESSPNKGSSPDQLSLNSKLQRTLMKNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFP6</accession>
    <name>A0AAV4UFP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_260501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012776">
        <property type="protein sequence ID" value="GIY56525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12725" checksum="A87496B3000B3D90" modified="2024-11-27" version="1">MLFQQNHSIKHLVATVAKEKKTTEGTLLGTAAHSSSIHPKTIKYFVSSPQPILTTPVGEQRAVFSHHCREKTFSGLPNPDCKAVKKRLAFKSISNPLPHFAFFLLSAFAFRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHM1</accession>
    <name>A0AAV4UHM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_394701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012890">
        <property type="protein sequence ID" value="GIY57340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10250" checksum="A809A2E664884A01" modified="2024-11-27" version="1">MSCTCNCSCQYTPQLYVPSCVKLFTQDNLLEYVCISRRFPKLRGIWVRFGVKLCCHGYRDDVIKMEGVLSFAVAEDLYSFSRFEENKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJ12</accession>
    <name>A0AAV4UJ12_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">protein kinase C</fullName>
            <ecNumber evidence="5">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">Prkd3</name>
        <name evidence="24" type="ORF">CEXT_208101</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01012916">
        <property type="protein sequence ID" value="GIY57510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJ12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20795">
        <property type="entry name" value="C1_PKD_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20796">
        <property type="entry name" value="C1_PKD_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01239">
        <property type="entry name" value="PH_PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000007">
        <property type="entry name" value="Serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000019">
        <property type="entry name" value="Serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020454">
        <property type="entry name" value="DAG/PE-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057764">
        <property type="entry name" value="Ubiquitin_PRKD1-3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22968">
        <property type="entry name" value="PROTEIN KINASE C, MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22968:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25525">
        <property type="entry name" value="Ubiquitin_PRKD1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00008">
        <property type="entry name" value="DAGPEDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <keyword evidence="13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="23">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="23">
        <location>
            <begin position="226"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="21">
        <location>
            <begin position="369"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="496"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="163"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="288"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="GIY57510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="660" mass="74896" checksum="0C6696ECDC341F4B" modified="2024-11-27" version="1">MIFFHQIIVDMEPPILNLPDEVTFMMQVGLARDSITVDVGDLNLKSLKDLACNFVDKKTYRKIDSFRHDYNSTNILLPINVASEVSEGTLVEIVVSGKDPSEDIQIMPHALTVHSYKTPTFCDFCGEMLFGLVRQGLKCEGCGLNFHKRCAYKIPNNCTHTRRRRSATSLYPRSPTESLGHTTSSAASFDDTMLGGSSPSRARSPSLNMGRPVWVERELAGRIRVPHTFVVHSYTRPTVCQHCKKLLKGLIRQGLQCKDCKFNVHKKCMEKVPMDCAGKLLKNGVNSNITTEAGRNGDGEPEGERESIEDESDTESEQTEKVNENQESQQDSQDNPDEEKIPANVTSSNNIPLMRIVQSIKQMRRKGSKILKEGWIVHFTSKDNMKKRHYWRLDTKSIILFQNETTTKYYKEIPLSEILSVEPTKQQVSTESGQTYCFELRTANVDYYIGEDPDISRGWEVAIRQALMPVTTPTTITLIKDVGGYQSSVSNFSRGSSRIWSIWSGLWGSSSNKWPNSSNQSNRKVRFPTKQEAQLKNEVSILQNIHHPGVVNLEKMFETPERIFVVMEKLKGDMLEMILSSEMRRLSERITKFLVFQILSALRHLHFKNVVHCDLKPENVLLSSDSDFPQVKLCDFGFARIIGEKSFRRLVGTPAYLGMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJY5</accession>
    <name>A0AAV4UJY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_563311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012989">
        <property type="protein sequence ID" value="GIY57904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7511" checksum="E892D5EDC82097D3" modified="2024-11-27" version="1">MTGIQRISVPNGVAFRSTHSMRVRVRRSPWVIDLPSVTCVRHGNHGFVQFVRGREVTGLLVNVKGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UR01</accession>
    <name>A0AAV4UR01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NGFI-A-binding protein homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nab</name>
        <name evidence="10" type="ORF">CEXT_378581</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013286">
        <property type="protein sequence ID" value="GIY60168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UR01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.2010:FF:000001">
        <property type="entry name" value="NGFI-A-binding protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.2010">
        <property type="entry name" value="NAB conserved domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006989">
        <property type="entry name" value="NAB_co-repressor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039040">
        <property type="entry name" value="NAB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006988">
        <property type="entry name" value="Nab_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038398">
        <property type="entry name" value="NCD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12623">
        <property type="entry name" value="NGFI-A BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12623:SF10">
        <property type="entry name" value="NGFI-A-BINDING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04905">
        <property type="entry name" value="NCD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04904">
        <property type="entry name" value="SAM_NCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Nab N-terminal" evidence="8">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="NAB co-repressor" evidence="9">
        <location>
            <begin position="219"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY60168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="547" mass="61154" checksum="84BF38E0161BBC16" modified="2024-11-27" version="1">MTSQPTNESELQLYRVLQRANLLSYYDTFICQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALQEWVNNPDYRACTVEETHRVHAPILPSESKMNSANCTLDRSVFNSKTNAMFQTPLMPAVPPSHSPYPVSPGPPVVRPGPLNLSQPSPVAPMQPSPPMPILSNSNSQSSPSPGAKDASSPQPPSALTFQQALCEYPQAPGSPTSLTPVLVESQIQRLSEAADLLVKTLPQFDPKPQNNKKKICKDLEYVMNMSEDDPRRMDEIRKYAAIYGRFDCKRKPEKPLTLHEVSVNEAAAQICKHIPALLTRRDELFPLARQVVRDSGYQYSKGHSRSQCYSKNYDEDSCKRLRFDGSPGALPDHNQMEEERKRRQDRLEAVTEQIKLLAGQQHDLKTGLQQSKDTHNVVAVGQIQNQLDLLATQHYQLINEQSELSRQLRRLDRIKGGRKRSLKGGERKENPAIGGLVANPGVFYIRAKRKKWVLPALSMVAKGGAPLKRGDIFSHRILINAKYFIESSQPGASTKNCFFGKDGEEKIAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0I3</accession>
    <name>A0AAV4V0I3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_285771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013746">
        <property type="protein sequence ID" value="GIY63466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0I3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12778" checksum="EDB0FCD6CC1E3C2C" modified="2024-11-27" version="1">MPELENNMPELENNMPELENNMPELENNMPELENNMPEYKNKKLENNMPVFIKQKNLQFNLNLNCPMLTKRFGKNVVKQRFVGPTKARTLNLQYFDKSPNTMPSFMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V242</accession>
    <name>A0AAV4V242_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">A disintegrin and metalloproteinase with thrombospondin motifs 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADAMTS9</name>
        <name evidence="11" type="ORF">CEXT_173091</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013811">
        <property type="protein sequence ID" value="GIY63959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V242"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.830:FF:000001">
        <property type="entry name" value="A disintegrin and metalloproteinase with thrombospondin motifs 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.830">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045371">
        <property type="entry name" value="ADAMTS_CR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010294">
        <property type="entry name" value="ADAMTS_spacer1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF278">
        <property type="entry name" value="ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19236">
        <property type="entry name" value="ADAMTS_CR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05986">
        <property type="entry name" value="ADAMTS_spacer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19030">
        <property type="entry name" value="TSP1_ADAMTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADAMTS cysteine-rich" evidence="9">
        <location>
            <begin position="66"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="ADAMTS/ADAMTS-like cysteine-rich" evidence="10">
        <location>
            <begin position="219"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ADAMTS/ADAMTS-like Spacer 1" evidence="8">
        <location>
            <begin position="334"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF19236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY63959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="582" mass="65781" checksum="376748548D5ACCD1" modified="2024-11-27" version="1">MKSDTYWEYHDDDAKCNRFHKQGQRLHVMARMLDYNSYPWTWSECSRHFITTFLEDLVYVLLCLSASDCGVLWKIFTLGGCRTQHMPWADGTRCGPDKSCLRGECVLDPVHDKPAQDGQWGEWQSYGPCSRTCGGGVSRSIRECDSPRPTNGGRYCVENEYDTSLVKPKYSHSLTVSTPECENSECRWRTDMFQFIKRKNVFAETKFHLWMDCPLGSTDFREEQCSSFNGKTFGFPGVDANVKWVPHYTGVEPKDRCKLYCRAAGTAAYFLLKERVIDGTTCGPETYDICINGKCMAAGCDHKLNSKEVTDVCGICSGNGTSCRVIRGKSIQMQYGYNDIVIIPAGASHIEVLQYGHENTLDDNYLALMGSDQQYLLNGNFMISMFPKSIQYAGSLIDYSGSHTIYEKINATKRLEDDLYVQVLTVGSLHPPEVSYQYTISVHEKRFTDGDWKTLGHPCNSICQGEQYRKAICVDRTTGKTMNDGLCHEQERPAHEARVCNPECFLSPSETEECIGPCRTKVWKYGVWSQCSATCGVGLQYRKALCIGDGNVELPDTECKNDSKIIEQTCATETCPYWKPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFN9</accession>
    <name>A0AAV4VFN9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_216861</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014470">
        <property type="protein sequence ID" value="GIY68951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050717">
        <property type="entry name" value="C2H2-ZF_Transcription_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14196">
        <property type="entry name" value="ODD-SKIPPED - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14196:SF12">
        <property type="entry name" value="ZINC FINGER PROTEIN 208-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="376"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY68951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="496" mass="56054" checksum="CC06FDADC9B8AD08" modified="2024-11-27" version="1">MHQMAQHPSASSQMEFSGMSSTNNISPHFSSVYHNFDQTDHTLTNRVSQHSEKSLGMPVLAIQNANYNRMYPTSRINCIQQTQPLASFASLSCDVPLEMSSYSTDTLCANEEESTLNRTETENPKYFASHFSLPSTSQNSVTSQEYRVNNRGAVKFKEDENYPKNKQWTDFSYGLAENISYNSRASQIHQHNFEGGIKNSKIECHTWEHSNFVTSLSENKNACKISNTISASEVSGNLKKISENKTFCRKACALKKLDVPQKPKTSYNCSKCPMTFRRKDYHESHECCHNVEKPYVCNFYDKAFSTCRNLGVHIMVKSDIHVRNAVNVFFLRGSLKSHLLTHTVEKPYTLHKCSKGYSKIIYFKRDMLKHAGEERSKCDSCGAEFSSEESLGAHKYHLTSNREPSIFILLSLELFVAASIWDFSHSTTNQVWTYSKLVKSCFPPPVMLPVVQDRNLLRKPPEATYSINIIISPFSPGIATLESPGIATLESPGTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W236</accession>
    <name>A0AAV4W236_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_704101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015502">
        <property type="protein sequence ID" value="GIY76601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W236"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7868" checksum="1CFEFB85296B924D" modified="2024-11-27" version="1">MDILNNPNEGFQEPTIQEAIDKKLNEPLLHGLEVVENMKSLGNCIVTNCPYYPSSNKRTHIEEIPFENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2Z9</accession>
    <name>A0AAV4W2Z9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_75391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015553">
        <property type="protein sequence ID" value="GIY76931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2Z9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11588" checksum="3C168A529B3A08E4" modified="2024-11-27" version="1">MLFSEDIFCSQANTGMHKYTGCGPALLREAGAHVYHFSLKLATNEILGTSPPCIDISTKELGCCAFSKINAMELRQGFQAIPGSHDAPAGPVTQPFEAGYCKCWLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W846</accession>
    <name>A0AAV4W846_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gonadotropin-releasing hormone receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GNRHR_0</name>
        <name evidence="6" type="ORF">CEXT_296601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015824">
        <property type="protein sequence ID" value="GIY78951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W846"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY78951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="233" mass="26333" checksum="47103DE894AE4A34" modified="2024-11-27" version="1">MNSTDVPSYSITPEVRLYILFVMFIFSLVGNTLVIKQLLSLNRRSFPKSKVLFLNLAAADLFASFGAVLFPCKWELLGKQWKLENVLQIICDSSNLFSFLLLIHADRHKPQSVSRGNGHQPVFGPFFGFSNDLSKLNVIVLPTAPHFQEAKVSAVTNGAIEIVGQIDVCCIVMLLQQIVFENGLIACRHSQHWSFVRGRQGQEFSYQYQERTKIAKMLGVRIKNVYGQKGQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFP5</accession>
    <name>A0AAV4WFP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_326411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016154">
        <property type="protein sequence ID" value="GIY81681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14351" checksum="396A84B1B04F7C3D" modified="2024-11-27" version="1">MIIRFRKPFFGIFLIKIAYPFIGMPIATGDRFTGDDPNLSVSSSKTSFHLLEDEIIHFLKKRPCDGVKPRVRGQPVGAENPRHAPFLTDNEGMTKQKNRHFLERGKEVETNRWLCLLLFILHGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGU3</accession>
    <name>A0AAV4WGU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_324741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016206">
        <property type="protein sequence ID" value="GIY82060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043764060" evidence="1">
        <location>
            <begin position="30"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9386" checksum="4C31129F60EAE17B" modified="2024-11-27" version="1">MPGNFSSSPLLKAALTMALIALYSAVLRGGEPNPLRYLPPNSSFATMQMGKISFSLLNYQDFNDDSKVSVYPQPCFVCVCGYVAGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHF6</accession>
    <name>A0AAV4WHF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_66361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016134">
        <property type="protein sequence ID" value="GIY81485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="14791" checksum="20E2AF1B442CC04C" modified="2024-11-27" version="1">MRLTDLCILHSTESFGNRKPAIIGWTMLTDYTLLEGRVRERKKGVEPVAVGFFRRNSTLRKCGFFKFNYAKHSTDGALFQWPSCASRISRYSAMMSARGGSSTGSGHSDAGGGGGWGGSARKSDEVLRKARLSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMR1</accession>
    <name>A0AAV4WMR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016400">
        <property type="protein sequence ID" value="GIY83574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY83574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9943" checksum="3A51646E9FADC572" modified="2024-11-27" version="1">MDSPKNTTLSTLDTAGMPLKKKKKKQAPANQCQKGTQLLEHTGGKFTKEEQRKKEKKRETSKRTRVLELRDVLSETPIMCRGTLAEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQ43</accession>
    <name>A0AAV4WQ43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_775801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016610">
        <property type="protein sequence ID" value="GIY85045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQ43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13816" checksum="1BFE272C3F0CB727" modified="2024-11-27" version="1">MSSGVPVRVVGLMGCPYPAAEQSSKQSQQYFPVKASKNDEGESFEKADDGGRPHRRLRLLCLQRGARGILGLGRVFRRMDDNNSGDLNLRRICERHPRHGSGYIGRGRGEIVQAVRQRRIRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTQ6</accession>
    <name>A0AAV4WTQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_181304_1</name>
        <name evidence="2" type="ORF">CEXT_444851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016680">
        <property type="protein sequence ID" value="GIY85708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="19662" checksum="CF40D5A6F5D5623B" modified="2024-11-27" version="1">MPARRKGTNLGRRTKKKKKCRRAKYKSIEETNKSNKTWHFRESQSQEARDERNRQRRLEQRQARRYVVNTRRAIDQQRQQAHRAFTSDSFLLLAFQYEPDVEYYVHYKVDIGTMDKECPHCHALKFKNEPAGLCCASVKVQLPEIETPPEPLHAYLSVRIQILACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WV81</accession>
    <name>A0AAV4WV81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_742181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016844">
        <property type="protein sequence ID" value="GIY86797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WV81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050778">
        <property type="entry name" value="Cueball_EGF_LRP_Nidogen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513">
        <property type="entry name" value="VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00058">
        <property type="entry name" value="Ldl_recept_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51120">
        <property type="entry name" value="LDLRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="LDL-receptor class B" evidence="2">
        <location>
            <begin position="18"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="2">
        <location>
            <begin position="61"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY86797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11743" checksum="7C8270ECD4482B6B" modified="2024-11-27" version="1">MNVCRPLNAEALVIAFAEKIYWSDTERERIQQSTLDGSRVENVISRGLGSVDFLAVDSTGRKLYWTDDQRKCIEVSELDGTSRKVLVWSNLDSPRAIALHYNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWI2</accession>
    <name>A0AAV4WWI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_378401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016737">
        <property type="protein sequence ID" value="GIY86085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10854" checksum="F74C15B8D615AC26" modified="2024-11-27" version="1">MQRLLNSDPMCLLPFGNRLEKGGACENLNKHKPCKRIKIGIGDPIAPESQCRADDGWLAEFNSELRMVREEEDNGKRNVRNDCHYLKFYIKNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYR9</accession>
    <name>A0AAV4WYR9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Membrane-associated protein Hem</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_324712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEM-1/HEM-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016936">
        <property type="protein sequence ID" value="GIY87428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031209">
        <property type="term" value="C:SCAR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030031">
        <property type="term" value="P:cell projection assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030866">
        <property type="term" value="P:cortical actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048812">
        <property type="term" value="P:neuron projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019137">
        <property type="entry name" value="Nck-associated_protein-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12093:SF10">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROTEIN HEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12093">
        <property type="entry name" value="NCK-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09735">
        <property type="entry name" value="Nckap1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1071" mass="123216" checksum="FBDE98E7BA956F45" modified="2024-11-27" version="1">MARSLIPSQQKLSEKLTILNDRGVGMLTRIYNIKKACGDNKSKPTFLSDKSLESAIKHVVRRFPNIDARGNSSQLNAVFSIRQEIMKSLSLYYYTFVDLLDFKDHTCEILTTLDACQLQLDITTNFDLTKNYLDLIVTYMSLMILLSRVEDRKAVLGLFNTAHEMTHGHNDPTFPRMGQLILDFDNPLKKLSEEFIPHSKLLFQALMSLQQVFPRRNLTVEEWRKSQMLSLVASPSQMLNPAQTETMPCEYLSLDVMERWIIFGFILIHQYLSQPPAQELFQSALHGGWVHTLFRDEVLQTHLYIQQFFESIKGYNKRVSEVKECFNFAVQNACLPGLLGPKVLFVFMGLSFARDEVVWLLRHCENLPQRHGGRTRTQAEDLIDRQLPELLFHMEELRALIRKYNQVIQRYYIQYLAGYDAVALDQMIQKVVCIPEEDSLILSSICNTISQLNIKQVEENELFDFRGLRLDWFRLQAYSSVAKYPLNLHEHRELASLLNTIVFHTKVVDVLDELLLETSDLSIFCFYSTVFENQFHMCLEFPAQTRYIIAFPLICCHFMNCTHELCPEERIHIGDRSLTLVNVFLDEMSKEAKDIITTICDEQCNLSDKLLPKHCAPLIAQVVNKKRRDKKSKVIAEPGKPGMESYRRTREELTTMDKLHMALSELCYAINYVSTVNVWDHVFCPREYLTNHLESRFNKSLVKMVMFNPENNEIAKPSELLTTVRSFMSVLQSIEKLCVLLQQTQPHDCHGDKTVTFLYTNWYLEALLRRVRNLQFSAEEYSDINELRALAELIGPYGMKYLNESLCWHIASQVTELKKLVVSNKEILMALRSNYDKPEEMKDLLRRLQNVDNVLQRMTIIGVIICFRSLAQDSLSDVLKERIPFLLSSVCDFKHHVPNGDSMIVSEIASAAGLPCRVDPALVAALRSQKSELGEDEYTVACLLMVFVAVSLPKLSRNEGSYYKASLEGHSNNIHCLAQAINGIAGALFTICGHGDIEDRLKEFLALASSSLLRLGQENDKEATRNRESVYLLLDLIVQESPFLTMDLLESCFPYALLRNAYHAVYRMENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7X1</accession>
    <name>A0AAV4X7X1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LysM and putative peptidoglycan-binding domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Lysmd3</name>
        <name evidence="2" type="ORF">CEXT_192451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000004">
        <property type="protein sequence ID" value="GIY91347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7X1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="285" mass="32313" checksum="CF92E6F8B6BD288E" modified="2024-11-27" version="1">MNSVVVEKFDFNSKRRLNTPLQNVRRFVSNKRKSRKSMYEKIPLTSPDTDSCSDEDITLHDIRHLRNDLNDTCENSLRKIKKLDQKRNGAVTENDKTSDPVSDLKRANNLISSQEFFGLKHLKIPVKKHSLLTEILKDTPETKSNSIIIEENCENIQTINIGIGSAGRCPSPQDSTAFFKRMDEDLVKIMLSTNTQKESLEAAAAALTTPQIQPLVKDPYNTVDWGIQWNYLILCIIIVAVIIPTAVALYMYTRNSHESEHHVYHNCSSSTESYSSAPELITDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7X7</accession>
    <name>A0AAV4X7X7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_270101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017342">
        <property type="protein sequence ID" value="GIY90707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7X7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9822" checksum="1E47C63CE5CE5AE4" modified="2024-11-27" version="1">MARPKSHKTPSVESSGRSLQDFEVLSVPYIYHKGYHFVIPKTHNGKFTHWKATIPHNTLQNQSAALYAEAPFVLVTEYRQYCLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGZ8</accession>
    <name>A0AAV4XGZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_562591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017723">
        <property type="protein sequence ID" value="GIY93932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9883" checksum="402DD997029DB3CF" modified="2024-11-27" version="1">MMEINPRDSNAFRLSNAVFHLREEGHGTGAPVLEMRVAPCLSGGDGDRMRDIISPESSLSLTPNHKSFRTQQYSEENLFWGDLVAFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH73</accession>
    <name>A0AAV4XH73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_126171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017733">
        <property type="protein sequence ID" value="GIY94014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7264" checksum="DB7EAE447733C7C8" modified="2024-11-27" version="1">MRGSQSCMYSYSSSQTAALPKMISQCLENNLRRRCQQGVVKEKQSRHSTTHAHLHLGPSMSGTPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJS0</accession>
    <name>A0AAV4XJS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_123661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017885">
        <property type="protein sequence ID" value="GIY95246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8822" checksum="6D47FAC934FAA312" modified="2024-11-27" version="1">MSDSTDPAQRRSAARYKRDSGDHGRSHSCKAKRFLVVLLASIFCRRFTALYLAGDSCRFDFRVQASIHFLQPCLLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMC4</accession>
    <name>A0AAV4XMC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_49421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000645">
        <property type="protein sequence ID" value="GIY96321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11377" checksum="D97B4B3BF7711782" modified="2024-11-27" version="1">MNGQKNKKRINNNNFFQVKTEKGNVRKRFKRSGGDFRTCHSVKNEKANERDSQMNECSDPNYQQLFVPVTHWPTVGHSCSYHIRPLHWYYFLSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPJ8</accession>
    <name>A0AAV4XPJ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7789 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_273881_1</name>
        <name evidence="3" type="ORF">CEXT_299281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000737">
        <property type="protein sequence ID" value="GIY97086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056691">
        <property type="entry name" value="DUF7789"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39299">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39299:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25044">
        <property type="entry name" value="DUF7789"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7789" evidence="2">
        <location>
            <begin position="33"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7789" evidence="2">
        <location>
            <begin position="170"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="315" mass="35979" checksum="991545491887DE46" modified="2024-11-27" version="1">MPTSVMNQEPESPISLSRFNLRPIPPRTQQTYFGKIRAFNTFTVLEWVYLAAALIALTASLGLTIQRLTVEKPSESDFTFAILLLLTIVFCYQYVIHSIFTERWDELMVFVISNVIVVVYVIVNYLKGEQPTTKLVRLILVATFGPFLIIVGILQSYRYCRSNNLIFNTVGGISSLQNSCRIFYICGSLLKFDLQLQLSMLILVMGKGVLAMTLTQKIILASGVPVTFLFIIFGFLGLFEPGYIIYKFYYTVTYEKDVDATYDATFVCGYFALVIWVSLIVATVYFVMYHFGKGLKEKKKFYENSRNSMKILEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR49</accession>
    <name>A0AAV4XR49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat and fibronectin type-III domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Lrfn5</name>
        <name evidence="3" type="ORF">CEXT_336761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018072">
        <property type="protein sequence ID" value="GIY96665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000082">
        <property type="entry name" value="Leucine-rich repeat-containing 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF211">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY96665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="339" mass="38689" checksum="A74FFF828F336BE7" modified="2024-11-27" version="1">MAIVPTEESGPHAFRQLYRKTKNHQNVRTGWGGMPSSGVEQKLKKINYLGQGGQPQWFLQRKFQKIVDQKRTSNLLTLSNPHIQFMMEKVLFTVILLSLLTQNVFSMSCHAKCQCIWRKGKQTAECSSAGFEKIPPGLESTIQVLDLTRNNFTLLPPNSFLNVGLVNLQKLYLARCGIEHIDDFALNRISNLVELDLSDNLISYIPTAAFRHLPLLRHLILSGNPLVIVPTQAFVELKTLIILEISNCKIDTIATRAFEGLEKLEVLKLDTNELQTLHAKTMISFKFLHGITLDGNPWTCDCELRGLRQWLNDNNVPYIPPACYRPVRLRDKNMDRSWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVB7</accession>
    <name>A0AAV4XVB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_232291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000932">
        <property type="protein sequence ID" value="GIY98533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11415" checksum="B25E628ACA6B31A1" modified="2024-11-27" version="1">MVVGTPAAGHRYVHFGIDQQAWRYVLWVPVSLELYSPINNNFYSAKAQLSTYSSSEYIKGKITAAFQDHIEKVYMKCRQNPMRFSITYASLPIMLSFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1N8</accession>
    <name>A0AAV4Y1N8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_737871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018472">
        <property type="protein sequence ID" value="GIY99900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1N8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8535" checksum="A762D67794E016FB" modified="2024-11-27" version="1">MQLAWRVATGILSIFSDDGGDHGDRDDGGRGDHDDHDDGRGDGHGGHDDGGHGDRDDGDHHDGDDALLLTPHWLTHSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2U5</accession>
    <name>A0AAV4Y2U5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein CG3556</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CG3556_5</name>
        <name evidence="8" type="ORF">CEXT_489021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018687">
        <property type="protein sequence ID" value="GIZ01572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015889">
        <property type="term" value="P:cobalamin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002157">
        <property type="entry name" value="Cbl-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051588">
        <property type="entry name" value="Cobalamin_Transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559:SF18">
        <property type="entry name" value="TRANSCOBALAMIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559">
        <property type="entry name" value="TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01122">
        <property type="entry name" value="Cobalamin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="271"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602157-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602157-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIZ01572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="483" mass="53384" checksum="E737FBF2CC1F1AF1" modified="2024-11-27" version="1">MNTVYANRKRGRTTGFFDSNKKCWIIPATAGKFIRININSISSQSSCTLSFLKLSVPETSDEYKLCPADSNKIPIVSLGSVIVRPYGGSYFENHLSFSLSFIIKDIECINKDSFRCDDNSCVSASKVCDGVKDCSNGADEVGCETGILAVKGIEEARQNAISWLKKKRSASWGWRDYTSRAVVALHLASDANFNGTILEEELMAKQTELKTAVALLRSSLTNSELSMFINSLLVTCHNPRKFYGHNLVTRLKEQVKESKGFTHPLAYLALCNAQESWPLKAISDLNNIINSSSNYPFIEAVAIIALSCNVNNTEDVGKIFLSGTLTLYENTISHFMDLQLEDGSFGNAYTTAFNYSKKVIGRLQCGRTQLEVSEELGIAQSVISRLWQRFQDDGNALISSGQEHSKSWKLNAAIEYLMDHLNSTSTDLLSTYLTLPLLNGKTLMDVSKINCSANPRKHGDDPVSELIDYLGPKCMCSFLCISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3U6</accession>
    <name>A0AAV4Y3U6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_77891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001334">
        <property type="protein sequence ID" value="GIZ01680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11534" checksum="7D9E513C6BB1CBB7" modified="2024-11-27" version="1">MKQSFQNSAWETLADDLIYEIFIDTPSKNKRSSYRMRIDYQTRQLTFSFNRCLLSTPESISHCPLSRYPQSYAYLIVVPFRNALWLLHLNNKYKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6E2</accession>
    <name>A0AAV4Y6E2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_600841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018831">
        <property type="protein sequence ID" value="GIZ02588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6E2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7613" checksum="2FFC13608E277710" modified="2024-11-27" version="1">MLSITQSDVLNQKISSTSPKWCLTEVAPPQNAININEVVPPQKCHHHHRSSSSIQKGHQHHLLSSIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y877</accession>
    <name>A0AAV4Y877_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_288021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018951">
        <property type="protein sequence ID" value="GIZ03462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y877"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7730" checksum="2D6D5753BBD071C4" modified="2024-11-27" version="1">MNNRVGSAFVVYDKGLEVYCHGFRLSDHETVYSAERMAIEAAIDFAINNNLQLSSIILTQDQCCRQSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9C3</accession>
    <name>A0AAV4Y9C3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_191110_1</name>
        <name evidence="2" type="ORF">CEXT_282351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018975">
        <property type="protein sequence ID" value="GIZ03593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9C3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF11">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="1">
        <location>
            <begin position="72"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="22740" checksum="6CE6F479D5266794" modified="2024-11-27" version="1">MCSTDLMAVSGQDLNNIVPVICGLNIGQHMYLQVGSSTGPFRITITTSGESEERKWKIRITQIPCRSNAMAPAHCLQYFTGAIGQFQSFNYGNLKSVEENTYFKNMNYAICIRKEASMCGATFTSDGDFNVNVWNSTINCSNDYLSFGTNRRCGKVPKEDLREIKLANSGPMIVSFVSDDKHTTGPLASDSGFTFKYTQFSCSSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YA94</accession>
    <name>A0AAV4YA94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019056">
        <property type="protein sequence ID" value="GIZ04243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YA94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15792" checksum="C442CAAA7824FAA4" modified="2024-11-27" version="1">MSGQEILSDKIKRLALQFLIKQYANHSFSPLMVNNELQLLDKDENTLKNSLQNYNCSPEHLLTLPIVPRHDPPLCEIFLQKFRFQNKENPVSLIVNDFSDCINRFFSDHYIIATDASKVTSQLQSPAFLAIKVFISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3H7</accession>
    <name>A0AAV4M3H7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_746981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019356">
        <property type="protein sequence ID" value="GIX66943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3H7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX66943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13253" checksum="251745E5235E5797" modified="2024-11-27" version="1">MVGWRSNKKRRACCQAEIHISKKGIHRWKFRKDFVAFWEIKAEARFRQQALTEITQLFRGSRFAAGTAPLPIQLSSTFKCKIFGVTESVIFFNVFFYVRKWLIFLIAARFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4S0</accession>
    <name>A0AAV4M4S0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_91891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001824">
        <property type="protein sequence ID" value="GIX66825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4S0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX66825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14582" checksum="F633933E0AFFD692" modified="2024-11-27" version="1">MKHPPAPQIRFRHSFDHPPIPKTEFEPRVSQSWKERKCFRRGRLRNCSSTFHWVELTGRREKKKRLERDMIRFEIERVHTELPGGWYHKPSSTTTTPFFVKARGARGVRDGCSYSRQSTEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5W6</accession>
    <name>A0AAV4M5W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_317911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019435">
        <property type="protein sequence ID" value="GIX67816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="18115" checksum="EE50554F492D43E5" modified="2024-11-27" version="1">MDLSLGVNESQVHQLKQILSLHPNLNNQTRNCIRTKLLFSTMSPSNIWPRRLVNTLRNSQSLNSVLSWTRSKICNWYTTSACNELPLDKFESEGYHFCFTVVLELRGLRIKSEIIPLEYDETGLLRIVIAFQWVLSIKSLTTCLSFSLESDCFLKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCR9</accession>
    <name>A0AAV4MCR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_797681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002069">
        <property type="protein sequence ID" value="GIX69630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="20329" checksum="C19E62B4B6A88B64" modified="2024-11-27" version="1">MVPKARVAKGEEENKMIAIIFPCCISKHLDWFALSLSNNCTRVGSTIKIDPFLKQNRSLGSLEAIWNIQGLSARTAAAILVFSVFLWLATTKRNHPSLSPVHPFPRSCERRDLLFSSAPRILVEVACSTLSVTVTIVCVTASAPRRIDAAFHGSGDSRLQTISIPVASNVRNRNKISIFTVIARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLE6</accession>
    <name>A0AAV4MLE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_388921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002339">
        <property type="protein sequence ID" value="GIX72690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8990" checksum="6FB56BC232ACCE96" modified="2024-11-27" version="1">MVTESEETKSPSSGKSCSREEPLKTEKDVAGKNDADSQERLHSALMWTPEQNRSGKSFFLLLPATMTRFAKKPHPVDLTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MM09</accession>
    <name>A0AAV4MM09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger SWIM domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Zswim8</name>
        <name evidence="3" type="ORF">CEXT_151671</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019944">
        <property type="protein sequence ID" value="GIX73375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MM09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031462">
        <property type="term" value="C:Cul2-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057945">
        <property type="entry name" value="TPR_ZSWIM8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22619">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22619:SF1">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25572">
        <property type="entry name" value="TPR_ZSWIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="143"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX73375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="535" mass="59789" checksum="D11C6004A8092DC6" modified="2024-11-27" version="1">MLTFIDISSGPNSLHRTSEEYNSALPAASLSQLSQSSVVDGQVTSLVELSAKVVAFHIPFEVVEHVCPPVPEQLQLRIAFWSFPENEEDIRLYSCLANGSADEFQRGEHLYKARAVKELLQIGFHLSATITPPQSLSVSKGTCNVAVTFDRCRITSCTCTCTSSASWCSHVVAVCLSRIHQPNHVRLRAPVSESLSRLHRVQLQKFAQYLISELPQQILPTAQRLLDELLSSQQTAINTLGGAPDPTAGASINEQTTWCLDGSTLHENIRKILIKLCVPSPIVFSDVNYLSSTAPPAAAEWSSLLRPLRGREPEGLWNLLSIVREMFHRDRNAIPLLEILTEEVLQCDQLNNLNFHIYSRFCLGGSAQRCHFIWDQVVIVVSSMHSNTHASQHACSSLCDEVVVLWRLAALNPALSPQDRQTLFGQLRCWHIKTLERVWKTRNSSSNATSSIKRADIEVFPGFRPAMEGCLLDGVITQFQELHMLKVEVEDGIALMFMLEQQNHHPLQLLLPMIVTTVAWHVFHLAEGVLLMWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMV0</accession>
    <name>A0AAV4MMV0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_419411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019975">
        <property type="protein sequence ID" value="GIX73693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="26479" checksum="2328CC2E26506031" modified="2024-11-27" version="1">MDTKNVPNTQQNGYQNNPNTLQMVTKAIRILSKMDSKVIKILSKMDIKILKKKNGYQNNLNTQQNGYQSNTNTQQNGHQNSQITQQTTQQNVHQSPVGSGNQNVYASHQNSEDLGQTFATAVSLPQYASSTQNHQQISSSHSNKQPIFCKLVQQPKWLFKSKWTAKQINYTPSIQESLQLQGNAGQPFAYVSLPSNYKSDFSSSGVVTSKIAHTKQSQTSFSNDESSEATGSRFKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN88</accession>
    <name>A0AAV4MN88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_234705_1</name>
        <name evidence="1" type="ORF">CEXT_288311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002445">
        <property type="protein sequence ID" value="GIX73809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12193" checksum="53E6C5FE29F3126C" modified="2024-11-27" version="1">MEEKELNTDILDFEVEDFCLEPERKKGKRKRSSILKQTKTLNLDICESMPEFDETEHRRRSQNIKRVSFADTFQVKELHTGNIYDIPGHHELTALQKKCSKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MU25</accession>
    <name>A0AAV4MU25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_533191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020170">
        <property type="protein sequence ID" value="GIX75486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MU25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16096" checksum="1FEE9CA51A1C84FA" modified="2024-11-27" version="1">MTLLSGIRLRSVRTHWGKGRTRGPRGAETEYVAANNMLSNKRENKDNTLSRGGLVKSCSYLRLGERGDGKNNPQKKNVWRELLITPCLWHVVLLNALCESHVLLCVTPWCIIFCLDLTMDFMHEPGFEVPFLSVFILCFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZU7</accession>
    <name>A0AAV4MZU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_413431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020355">
        <property type="protein sequence ID" value="GIX77768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11487" checksum="97F991D0C4856C45" modified="2024-11-27" version="1">MVYVNNLSAMIPARTLTVKRCCATPGLVKCVLYTAHMWMLQVLNTPSHINNVSSVTKHIIRSADQTQLFEETTVQMQHAVNNLPPALLELFEDRKHVSLRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N410</accession>
    <name>A0AAV4N410_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_365111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002904">
        <property type="protein sequence ID" value="GIX79163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N410"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7813" checksum="B611314E293486C9" modified="2024-11-27" version="1">MLVTFYSFVSNLAPPCDRRKRYPPFNLEDLLRGHSVPLGNAKMENAGVTNFILDLVVLRTMQNVGLCTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4H0</accession>
    <name>A0AAV4N4H0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translocon-associated protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SSR2</name>
        <name evidence="13" type="ORF">CEXT_112641</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAP-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020474">
        <property type="protein sequence ID" value="GIX79185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4H0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008856">
        <property type="entry name" value="TRAP_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12861:SF3">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12861">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05753">
        <property type="entry name" value="TRAP_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016400">
        <property type="entry name" value="TRAP_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043786267" description="Translocon-associated protein subunit beta" evidence="12">
        <location>
            <begin position="27"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX79185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="21714" checksum="2444A7DBBF6740C5" modified="2024-11-27" version="1" fragment="single">ICRRLIYFSNMHPFLILCFAAVLSSAVSDELSPARLLVHKRLLNKYLVEGRDVVVSYSIYNIGELRDASFNSEDFDTATGFLATKLDRMGPNSNISHTVVLRPKKTGHFNFTAAEVTYHPSEESHEIQVAYSTEPGEAIIIPAKDFDRKFSPHTMDWAAFAVMTLPSLGIPFLLWYRSKSKYENIVKQKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6V3</accession>
    <name>A0AAV4N6V3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metalloendopeptidase</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_641131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3 4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01020576">
        <property type="protein sequence ID" value="GIX80221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6V3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF883">
        <property type="entry name" value="ZINC METALLOPROTEINASE NAS-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043109113" description="Metalloendopeptidase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="5">
        <location>
            <begin position="50"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX80221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="247" mass="28105" checksum="6BE658C083B271E4" modified="2024-11-27" version="1">MKMALLLGLLFLCAGKSLALPLDGLDNSAMENPDLFGGDIVGIEPGEDRSAVVNRTRLWPGGIVPYVEDPGLKETVRYMFLIERAMDQYKRSTCIRFVPRTNEKDYIRLHPGQGCYSFAGRVGGPQIVSLGVGCNWEGTIVHELGHAIGFYHEQNRSDRDEYIKIFWENIKTGQEDQFFKLAPSENQLLTPFDYDSIMLYGSLTFSKDKANRLRTMEGKDGRYLKDVNTKKLSEQDIKRINMLYDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8L6</accession>
    <name>A0AAV4N8L6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_686751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002971">
        <property type="protein sequence ID" value="GIX79784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14667" checksum="89B0705F67E519D6" modified="2024-11-27" version="1">MRDPGPKNGLQGRPTVQPQAYRNLFSVLKRRKVELGHQRNKALVVKSKERHRRLENSGSFCEWPFFSATEKNTQRTFICQWATPSLRPEFLEKCEILILFSNQPAATTHRGAALIAIASMMVDVPVMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9H3</accession>
    <name>A0AAV4N9H3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine proteinase stubble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sb_14</name>
        <name evidence="3" type="ORF">CEXT_528691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003080">
        <property type="protein sequence ID" value="GIX80985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9H3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF116">
        <property type="entry name" value="FI16631P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX80985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="303" mass="35726" checksum="568854B7050F51F8" modified="2024-11-27" version="1">MRNRSGLHPVGWQHVRPTPLRGVILKKLWVLTAAHCVTSYSARHFTVRVGEYDLTKPETDHIEKDYSVEKIHLHPDLYRPKRYNNDIALLKLHKPIEYNGYSWPTCLPDNDDDFSGQEGTVIGWGFMKENVASRILSDWNDLMTSYFPPYLHRDNPYLPVYLNRDNPYFPAQYQQNNPYLAAYLHQDNPYLRAYLHQDNPYLPVYLNRDNPYFPAQYQQNNPYLAAYLHQDNPYLRAYLHQDNPYLPVYLNRDNPYFPAQYQQNNPYLAAYFASRQSISSCIFASRQPLSCCIFASRAILIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQM0</accession>
    <name>A0AAV4NQM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GPS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_127446_1</name>
        <name evidence="1" type="ORF">CEXT_137221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021157">
        <property type="protein sequence ID" value="GIX86610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12473" checksum="8FB6FC17C28A6E45" modified="2024-11-27" version="1">MLSSSDDIRSPSVSLSLHRFRYGYGSILHRGLDMEYQLHSRIVAVAVQTGQRVVGARASRLKVKARLAHLNHTVNRQIMWNISCGLADFLREGYPCLCLFAEFFFYVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYE8</accession>
    <name>A0AAV4NYE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_243771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003855">
        <property type="protein sequence ID" value="GIX89378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8868" checksum="50C33D5EAB3AD66F" modified="2024-11-27" version="1">MNGRTHISLNSLPFVGECLSQLREEDDGPHYFRGSLILLDAKSYKINTCEGKKDCPYRNQQDKVVEFIIRPHRFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0J3</accession>
    <name>A0AAV4P0J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_548041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003873">
        <property type="protein sequence ID" value="GIX89553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14839" checksum="5A5707B604710821" modified="2024-11-27" version="1">MSKERSFEQNASWKNDSLLGVCFRLKRRVIAQSLLPQKHAVSIFPEIFVHGINESRAGKTAMEDFEIQDHTMILSSRVIRGRYLKERITGRAAANFRVLMQVIFFPALRIECIVISEWLLIWSCEIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2K5</accession>
    <name>A0AAV4P2K5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_609201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004020">
        <property type="protein sequence ID" value="GIX91390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX91390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12166" checksum="2AFC1DB3DFB3DCFA" modified="2024-11-27" version="1">MSLGSRQGSSKPKRKGREGRVKTYCTLLRSPRSLASSVHCGTDSNEFHSCLDRIWLIGKDGRIRTLAHQSFAVGGEQKYVKKICKVLLFIYLCVFLSFNSSIILTARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P345</accession>
    <name>A0AAV4P345_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_226251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021480">
        <property type="protein sequence ID" value="GIX90176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P345"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9839" checksum="054ACB287EA1FE24" modified="2024-11-27" version="1">MKSQTITEDTGMTGHFPPKGGTQSLCRRFPEVQEQRMLGEERRPNQLVCLFSISIPSGEKLGSSWDQEGVRGYFMVFRALIVSVKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4D4</accession>
    <name>A0AAV4P4D4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_110941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003954">
        <property type="protein sequence ID" value="GIX90611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4D4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14360" checksum="8DC90921F518858B" modified="2024-11-27" version="1">MGPEFVCRFSVRRNHGAWFFFRKGCSQTKSFWSPGNSDRKPFVKIKIPVPSLETSRIDTFVAKSKFLTFKQHERPQSREKNGALFFQFLQHQDKKHHTTQEISSLWFSPQHIFGKRRPCRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P679</accession>
    <name>A0AAV4P679_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_257180_1</name>
        <name evidence="2" type="ORF">CEXT_518791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004046">
        <property type="protein sequence ID" value="GIX91671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P679"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043450307" evidence="1">
        <location>
            <begin position="19"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19545" checksum="A9D30BE93CE98238" modified="2024-11-27" version="1">MQLLSIIIIGVVLGVASCDIDCFNKETIKCRPDFGKDARTSILEYCRTHVPFVKCIRDSCAKCKVGFLPEAERWWAAIKDACTDGTALNKNLDSNIACITSAIADADCTTDSDQDLKDMPDDQAMCKEFDSLRDCLYQRIESACSRNVADDFLTIYGAMVDYQLKICDEVILKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8K6</accession>
    <name>A0AAV4P8K6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_189101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021647">
        <property type="protein sequence ID" value="GIX92036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8K6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11553" checksum="9A28A11179827ECD" modified="2024-11-27" version="1">MAKKNEEERLPVYYSVFSGSFLNPFVPCYESLSILLVFRFKRGGRGLQLASLKTLFPFNACLLSLPFAGLRKRFATRRRSSRTAKGIVLRRNRETDDFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9P2</accession>
    <name>A0AAV4P9P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Troponin C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_728181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004151">
        <property type="protein sequence ID" value="GIX92718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX92718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7790" checksum="3064006F89618E07" modified="2024-11-27" version="1">MVEELLTTEQIAMLRKAFDMFDRDKKGSIQTNMVSTILRTLGQTFEEKDLKELIQEIDVDGSGRVGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PED6</accession>
    <name>A0AAV4PED6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_633561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004531">
        <property type="protein sequence ID" value="GIX95545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PED6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10452" checksum="DBE6F160CD2105AD" modified="2024-11-27" version="1">MLVEFHAFTRNFFFIFTLHRLELKSALYNKCLSEDYLLTLSSFEPDKGNGGTVSQSRKRSRIENRMNLIPEVLRNGFTHRFPGHSSSNTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PG31</accession>
    <name>A0AAV4PG31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_269741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004610">
        <property type="protein sequence ID" value="GIX96115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PG31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8853" checksum="256EE4417E905912" modified="2024-11-27" version="1">MIKHESNHPKQLLPNPTGSRAEIETGDFSMFYGDDSGCQECGMRSRRVITSNYRLGSHRGHWGPRVTSDSESMKEDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q871</accession>
    <name>A0AAV4Q871_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_705551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005692">
        <property type="protein sequence ID" value="GIY04286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q871"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12445" checksum="FD10321BDEB8BC46" modified="2024-11-27" version="1">MAAFLKEMVKKKKKDSNDVCFIITTTTPAEFILENAVREKTPRGYELKEQHSFVKCFILFRNDPEKFMCYHSTESYADGYVYEIGLWKSIASSSETGGPGIWQFGINGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QKC9</accession>
    <name>A0AAV4QKC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_582411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006282">
        <property type="protein sequence ID" value="GIY08724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QKC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8398" checksum="39DD583D56E8BD58" modified="2024-11-27" version="1">MLACTKQSGACSQALPAAGSINDTELNHTSFELSDFRGQLLWNMIEELKIRFSNTSLHYSVADSLFNRVIEYLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPJ2</accession>
    <name>A0AAV4QPJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_54401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006385">
        <property type="protein sequence ID" value="GIY09468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="20040" checksum="EAD47D1C05C4775A" modified="2024-11-27" version="1">MQSFQKETGGTTISLGTGVPVPKALVYGAIYPRHIPERTCNYLQRRNSNRHSSCTSPNESLMFMDIKHQRLFLEGLMNADLDMKNVSNVPPRYYHGLASSANERFNVRWPEWKNCSNWKRISKSQLNHRPSNMFVSNWIDEQLILPHVDHFRDLKYDELDFETRDSKNSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWY7</accession>
    <name>A0AAV4QWY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_732641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007051">
        <property type="protein sequence ID" value="GIY14143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="17862" checksum="E7F439C49502E4DF" modified="2024-11-27" version="1">MALLHHLNPKFKVKTRGLFFFFDCSKEDSKGLKAENPASLKCVVFSAGIVATAFELRDDKGQKRNKCMRATAEVDSVALKKRFFGKKGSKSLLAAKSGVPKTWNSGAGNGKRTNQGQENEPSVIVQKRAIHMRSVVLASSKEELNRHVGQVVSEGDNNLEHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZ90</accession>
    <name>A0AAV4QZ90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_283731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007143">
        <property type="protein sequence ID" value="GIY14790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZ90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11670" checksum="84AC4E31D32FB05F" modified="2024-11-27" version="1">MSHSGVSNYVCQIPLLVREEHTWEVIHWLGGCRHRLRLSLQDPLLDTTHSHTVYKRPGTDFGISLTALSRESSISWLFEHSTDCSISLTLAKIFHSATLNNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5M3</accession>
    <name>A0AAV4R5M3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DEP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_323992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007246">
        <property type="protein sequence ID" value="GIY15545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027244">
        <property type="entry name" value="IML1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179">
        <property type="entry name" value="DEP DOMAIN CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179:SF8">
        <property type="entry name" value="GATOR COMPLEX PROTEIN DEPDC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEP" evidence="2">
        <location>
            <begin position="472"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY15545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="527" mass="60700" checksum="79ABAD75D254DDB9" modified="2024-11-27" version="1">MYKIVLKLPLFYLGVNEYKSSTLSRRELHSSSSNMSSNLGDGVRMSSSLQPSDNLSWLWGATGEQEWTPAITTGVDWKSLVIPACLPITTDYFPDRRSLQIDYVISDYVLLPEDIISENAIPRYFQNDEDTVRRPLTTPEVYNELICQRLQQGFQIIVLSKQHASYPVTQVSSSPQFSSALFKGGQNIDQEFLLSIGRIFHKLNLDGPRITVTQYRPRHPHREIKVHYCYRFHAPDSDTYGVSWVDFTSERLENYNWNYLDHYICMRGEGEFELKESLKFWRLRMLLLPAGQPETRKIIDGSERCDLYNKFSDDDKTQQKDGVVKFLDVMNKIKRVSSKKPKFKFPSLPRRSSIGHASINILSASSLRDRVGSNRVHDRPRMRSNSARMGARPEPVMPTGRISPATEVDGRITIPRSENPLITSNENADEYFFFLQIKKLSENSSESEIIQAMKHPQDGLNFISKVGWSNYTFVSAEAVAWLLLHIDTIIMEQQAIQILQNLLEKDLICHVSRANTFFYFLVFTYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RB77</accession>
    <name>A0AAV4RB77_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_111539_1</name>
        <name evidence="2" type="ORF">CEXT_761101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007715">
        <property type="protein sequence ID" value="GIY19084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RB77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349229" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="26627" checksum="0919C659B89D9504" modified="2024-11-27" version="1">MWYFVLIVFGFWNGAFSANQTCIENLRWTCRNIHMIPNELPGTEDELKESCSELENNKRCLMERLLECGSNNYDDLEVARSDLPRMINTLTEICQEDTELHASYVQHMACIKRFVSANNEKQFCRDYTTSAMVYLRGPIQRKKLEDELDYRNKFSQCLVPLLSMNCFVTYISGSCEHGAGKMSIELIQKAGSVAEQCPASIRIDVIDLLKALESATEEQMFVMRLITSLNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGR7</accession>
    <name>A0AAV4RGR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_190231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007804">
        <property type="protein sequence ID" value="GIY19896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="18229" checksum="179F4BD3D5A59821" modified="2024-11-27" version="1">MTCRNNQEHLVSALICIHKNRRESFQHFTKGTSDNSSVRISRGGPLREPIPRPRGGSLRNPFQGVHQCRRFMLIQRDQRGRHCHARFFKGRQPLRTIGRRFRSAWQQWGKILSPSFHGDGEGVEGRRHPLRIAREKGQFRRRGTEAKRNVEDVILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHR0</accession>
    <name>A0AAV4RHR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_48851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007767">
        <property type="protein sequence ID" value="GIY19533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17559" checksum="02CA839F570FBD9A" modified="2024-11-27" version="1">MAGVEWRLCGFVRDFSGMPFRKALWDDSNWMFIGLKKDGRIRKSPVRDFLRLFGQIHSVSSVSDVPQKRRRAQTQKNSLWDFHLFKADKHPVKSSRRALKGHSRNPEQSHINATQPLHKIVCFPLEQKLRRRCHGKEKQNQKKIAAENAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJ90</accession>
    <name>A0AAV4RJ90_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytoplasmic dynein 2 light intermediate chain 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">dync2li1</name>
        <name evidence="14" type="ORF">CEXT_643501</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein light intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008025">
        <property type="protein sequence ID" value="GIY21505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJ90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040045">
        <property type="entry name" value="DYNC2LI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13236:SF0">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13236">
        <property type="entry name" value="DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY21505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="321" mass="36377" checksum="2B15A7C8735FF902" modified="2024-11-27" version="1">MTKKGGKSSICYKFLERTETPKSTLALEYLFGRRNKGIESGKEICHIWELGGGTLFMDLLEIPITIENLWNLSVVLVLDLSKAEELWYNMQTLLDTIRKLIDRALESSKDPTAKNKLYEIARSRIPKDHEDLQSIEPFPVPLLIIGSKYDLFQSEDFQKRKLICKCLRYIAHTYGASLQFVSSKSETLITKARVSISAMVFGTSSSKTTASDHNKPLYICAGADSYESIGSFTTLNVENKTFTEKNMTSEVILKAILIPFFDAHSLVPYSEIVNRSLEAVKHIFSSYFSQVESRSILPDDPANDPHFKEPDIDNLRAQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLD9</accession>
    <name>A0AAV4RLD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_121451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008049">
        <property type="protein sequence ID" value="GIY21691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11544" checksum="25FF780B857C5BCD" modified="2024-11-27" version="1">MSMHELTDPFEVIRCVMDMCQHFHFLATMSIPMLRVSLISRISFIPTARNPGVMSGIMMAVQQVHLCQFSDEGRSYVISQHIYSEMLLTFMVVQRPPNHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQI6</accession>
    <name>A0AAV4RQI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_669271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008307">
        <property type="protein sequence ID" value="GIY23740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7990" checksum="CE1B9B5D0188D433" modified="2024-11-27" version="1">MRIGILTGLESRSKTLWSAVRIYLSGEMDGGDLLPPNSSITFSARVLHPLEAPFPILVHLVAAADKSNNRWMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RT41</accession>
    <name>A0AAV4RT41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_496821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008448">
        <property type="protein sequence ID" value="GIY24769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RT41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12315" checksum="68EAEBC5554D2CD4" modified="2024-11-27" version="1">MNQNIYHISLRLRTGIRFHTESEQSLPGNYVMSLTNYSPMYERQRFRMNESQRSNGGWEHHRLPSFARAHSSRQKMHGHRFALKHRLFISQFPSRPEDGGNTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0H1</accession>
    <name>A0AAV4S0H1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_793651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008719">
        <property type="protein sequence ID" value="GIY26671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0H1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10831" checksum="C42F8298CA35D42F" modified="2024-11-27" version="1">MLEPPTRSTVFEPPTRSTMPKPPTRSTLLDPNSFNNAQTSNPFNNAQTSNSFNNAQTSNSFNIAQTSNSFNNAQTSNFFQKCSNPKLLPEMLEPQTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1B8</accession>
    <name>A0AAV4S1B8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coiled-coil domain-containing protein 130</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CCDC130</name>
        <name evidence="2" type="ORF">CEXT_457551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008884">
        <property type="protein sequence ID" value="GIY27958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1B8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="33200" checksum="AE5453ABED38D442" modified="2024-11-27" version="1">MPFNIWCNGCENHIGMGVRYNAEKTKVGMYYTTPIYKFRMKCHLCTNHFEIQTDPQNLDYVILNGAQRQERRWDPTQNEQVVPEDKEVSKKLSTDSMFCLEHSVNDKVKQKTILPSLLKLEESKEKWKEDYLLNKTLRQQFREKKKEVACIEKRDKQLLERYSLNITLLPETDEDRRLAGLLKLDSLHTIEEKQRINREEALSRPLFSPPCKNIPAVANSIKEIKVKKILKPLTRTELGIIQKDNCKKVIESQEEFNKLKETNNSKTSLVAFDYGSSDSDEDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1J6</accession>
    <name>A0AAV4S1J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_78131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008740">
        <property type="protein sequence ID" value="GIY26829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7882" checksum="E7923FD8D7279B34" modified="2024-11-27" version="1">MKDHGVLIIGIPGLITIHWAWLRLQDNELFVRKEEKENHPLIMGFQNIENKLTSIFSSKPKNNPNSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAD2</accession>
    <name>A0AAV4SAD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_752371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009296">
        <property type="protein sequence ID" value="GIY30934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="9032" checksum="2E09FE2BB8239C74" modified="2024-11-27" version="1">MNWNSLQSASWRQMVWMDESHTINDALASRYSTYKNLNLRRVLPRLKKEKKGCRRSTRESGISTLREHRRVILPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAQ2</accession>
    <name>A0AAV4SAQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_217671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009012">
        <property type="protein sequence ID" value="GIY28998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12444" checksum="F293867CAD0B43AF" modified="2024-11-27" version="1">MPSCTEDISEKRVVLETGIAPAVVAAVLCQDYLQGNAHEIQKHSKISAEVSHYRLLKWKQQSRKRIAGREGRIKKSGADSQRGVSAWSLFESPTDSREHRPRPHLCQKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE13</accession>
    <name>A0AAV4SE13_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">NTRK1</name>
        <name evidence="22" type="ORF">CEXT_207251</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01009261">
        <property type="protein sequence ID" value="GIY30665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043121">
        <property type="term" value="F:neurotrophin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005030">
        <property type="term" value="F:neurotrophin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990090">
        <property type="term" value="P:cellular response to nerve growth factor stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010976">
        <property type="term" value="P:positive regulation of neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051897">
        <property type="term" value="P:positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000033">
        <property type="entry name" value="Tyrosine-protein kinase receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF614">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="12" id="KW-0221">Differentiation</keyword>
    <keyword evidence="19" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="10 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18 22" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="17" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="GIY30665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11119" checksum="FBD9C2E8549EEDC5" modified="2024-11-27" version="1">MCVYTWGLLKSITSLREKISFVQTLGEGAFGRVFLGTVDYLTPDEPTTLVAVKTLKDTNFSDAKVDFEREAELLTNMQHDNIIKFYGVSTDGEAPMMIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE33</accession>
    <name>A0AAV4SE33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Pde11</name>
        <name evidence="7" type="ORF">CEXT_229231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009294">
        <property type="protein sequence ID" value="GIY30926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="6">
        <location>
            <begin position="169"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="83"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY30926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="277" mass="31877" checksum="1A678E48CEBD3E3B" modified="2024-11-27" version="1">MPSHICQYAKPSVCQVVRCLCEHDSLITRPDETTGARTARHPNMEEMLLNIVYQPIDLLNVMYMFLCRWLLSVRKNYRPVAYHNWRHAFNVAQMMFAILRVSKLGQLLGELETLSLLLACLSHDLDHRGINNSFLKGNQILSHLSAEEYRNVIHVLKKAILATDLTVYFKAMLMTACDIAAITKPWKIQRKIAVLIANEFFEQGDAEKQLKLEPTDMMNRDKKDKLPLMQVAFIDSICLPLYEAFALISDKLGPLLEGVKENRAQWLKLAEEKRTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHS9</accession>
    <name>A0AAV4SHS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_616021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009712">
        <property type="protein sequence ID" value="GIY33998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12923" checksum="60AF58E273ABC400" modified="2024-11-27" version="1">MTMRFFNYELRYMIKEGQFVDGPFRCRKVSCPAEDTTSPQRSTDSAAPDRKKERKIRKKVRWSALSSAITSARSHAIFSHRRTVKEHKTHCLCRDKDRRVLLWKTVLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJB7</accession>
    <name>A0AAV4SJB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein heavy chain 7, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Dnah7</name>
        <name evidence="1" type="ORF">CEXT_748831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009782">
        <property type="protein sequence ID" value="GIY34523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF1">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="21591" checksum="C9C90A052497E286" modified="2024-11-27" version="1">MIVRHGFMIVGMPFGGKTSAYRVLAGALADIHEQGLMDENKVQITIINPKSITMGQLYGQFDPVSHEWSDGILAVSYRAFAQSTVKLQIVSRCGMIYMEPGALGWEPLFTSWLNELPESITEEHKVLLTELFEYFVVLTVLCIEQPTKVILFLTQMEEPLRLIDLAYSFPTPTFNFKIQPAIHQNTPALIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWN4</accession>
    <name>A0AAV4SWN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_133694_1</name>
        <name evidence="3" type="ORF">CEXT_487891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010201">
        <property type="protein sequence ID" value="GIY37666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY37666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="407" mass="46745" checksum="D6B0C10B405597C7" modified="2024-11-27" version="1">MTSSSVTPKTLTDSINTKESENLLTTKTNFKATTSKSKERHLTENSHRSSVFNRKFAFIHNEDNNGTNLYTTPIPANIQLQTKSYLPFKNNETEQRINLDRNIPFSRPDLKTFDKNHPHHVPSDHHVYGNDRWQSVPRTDPFSAVRNPYSLQNTGTLEFDRNSDRNKGYDSHHHINNDRIHPLPLNPQRNTNPKPLEILDHPSQRHDRHPGYSQGRPTSNYPRPVEIPNPQDRNPYPTNRYDYNRPISQPRPADISHQPNNPQPWNNNHNRVNTRSPPRGVNRPEETQVHRQPYPQQPAAAQNPQRNDDTWRMNPSRPSNSNSQPGRNNFYASQPQFRPSEVIATTQKSVQKKSLCPSYIAPRPETVDEDKVCTSKATVIATAVSVTLVYLGVVAGAVVGYRWHRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZJ3</accession>
    <name>A0AAV4SZJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010246">
        <property type="protein sequence ID" value="GIY37982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10772" checksum="B35259A44EC8F941" modified="2024-11-27" version="1">MPLRKSPTVVHSIKHDRQGIALINVSEVLLSRGRLYLLHFLPNSIFRIINALEGHSVDDLGLAALNRFRMFRSKNVYKIPKYRHFFHCFNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZP5</accession>
    <name>A0AAV4SZP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_557191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010438">
        <property type="protein sequence ID" value="GIY39265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10632" checksum="41FF03AFCE101D23" modified="2024-11-27" version="1">MLPLMRVDTFPVLWEEDKPGRNQHLTCGIEETSPSMYVIGRDSKEAKMKRIASLALIRTRYRDERKRNRGDERDRFLPKQFRYRVRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0B1</accession>
    <name>A0AAV4T0B1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_720161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010361">
        <property type="protein sequence ID" value="GIY38821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0B1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9603" checksum="50A5E3E219A9EF0F" modified="2024-11-27" version="1">MATIVGSKPMFSITNEANLTWQRHREGIRSGSIRMRTARRDRCRPPSGGFVILPHPLFSPAILLHSILLFLSSAIDLVRILWHKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1U6</accession>
    <name>A0AAV4T1U6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010592">
        <property type="protein sequence ID" value="GIY40275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13340" checksum="7ABFEF46869AB28F" modified="2024-11-27" version="1">MAKIHSIPTPRRRIEARIDFVIISSPNPSPPLRGGQNEREGGLQEIVPNYSSSCRRGGMEDNSSPPEMWKRGGKHKVEGGGGGVEVEQGMVINVIWGRQSFSSIDRVQCLIKVLALGFGPMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T800</accession>
    <name>A0AAV4T800_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_159065_2</name>
        <name evidence="2" type="ORF">CEXT_678211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010834">
        <property type="protein sequence ID" value="GIY42319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T800"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043853759" evidence="1">
        <location>
            <begin position="22"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11394" checksum="BA7FA533638A2106" modified="2024-11-27" version="1">MRASKLFFLFCFLFVLTRTQAQFFTKTTNSIPRLEGQINPFLPNLVRHVAKQLHFNAMKSELEAIELRGQYLATNGKAERESEPSGKQRLIYDENLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TER0</accession>
    <name>A0AAV4TER0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_382001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011228">
        <property type="protein sequence ID" value="GIY45058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TER0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15364" checksum="278C40D6F3BB663A" modified="2024-11-27" version="1">MNAPFISVLSGEIFHLITCKLGKLLERMCVILLGHERTGRRGGERCLKIVWHLRLINGADFCSSPGRRRKEDPYQYEEHSSSVLHPPETFPGRSSNIHLSPIFGRLRNDRTKTHPRLSFPRGDFGSSAGQRKGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TF53</accession>
    <name>A0AAV4TF53_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_558991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011191">
        <property type="protein sequence ID" value="GIY44740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TF53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001540">
        <property type="term" value="F:amyloid-beta binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039576">
        <property type="entry name" value="APBB1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14058">
        <property type="entry name" value="AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14058:SF8">
        <property type="entry name" value="PROTEIN FE65 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY44740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15336" checksum="9936EC942B126F83" modified="2024-11-27" version="1">MLTANTENNLNQTHGLKSSDTEDSFPGIDNGNARINLPTFQALCSCDSSVQKPGASVVSEKLAGSTKYERHSCDESAESDCLPSGWERHEDDSGPYYWHISSGTIQRDPPISYSCNRVSSRLSKRSRFEFFKKNIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMF7</accession>
    <name>A0AAV4TMF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_466511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011449">
        <property type="protein sequence ID" value="GIY46631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="39" mass="4712" checksum="8C1B4BC81B75F81A" modified="2024-11-27" version="1" fragment="single">MKRIWDRVRESVGGRSIVYVVSRRQSQHVLSHYLKRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TP68</accession>
    <name>A0AAV4TP68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_399211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011312">
        <property type="protein sequence ID" value="GIY45738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TP68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7154" checksum="E56AC0352A232E3C" modified="2024-11-27" version="1" fragment="single">HEYANASGCSKTGFSVPVVMAVLSSAWEITKLQVRAGIHANHNVHGAHAQRHDGSHHTKITNSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U068</accession>
    <name>A0AAV4U068_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_58551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012075">
        <property type="protein sequence ID" value="GIY51158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U068"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11545" checksum="5E652A59A790D48C" modified="2024-11-27" version="1">MENKKHSYALDELQLHRSMKCIVLMESSFKIQTDMQNKEETDEFYRQPSKMNGEIDAAVLEWKALLIKDRFAAHLKLINAMPPAHSWNAEIPEARQLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9H5</accession>
    <name>A0AAV4U9H5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pps</name>
        <name evidence="2" type="ORF">CEXT_667011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012514">
        <property type="protein sequence ID" value="GIY54434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9H5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.10">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051549">
        <property type="entry name" value="PEP_Utilizing_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615:SF1">
        <property type="entry name" value="PPDK_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP-utilising enzyme mobile" evidence="1">
        <location>
            <begin position="160"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="243" mass="27212" checksum="C91EC7DFED74A9DB" modified="2024-11-27" version="1">MDHKLLINLLQNLVKTSNIEEVKKKEESTSKIFSQLQVPLDFTSKCYLRFVLPNCRRGVRAREISKSTVIKYEINDLLNTRSPGIVQKAIQRKKLFPILEQYIFPEISKGIPKPLNYEEESSDSYEFIADLTMKGVPVSQGVTKGFARVAMSLEEAAHLKPGEILITYSTDIGWSPYFPIISGVVTELGGLISHGAVVSREYGLPCVVGLQGACKRFRSGDYVLLDGKKRNFAKVAPTRTVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UE96</accession>
    <name>A0AAV4UE96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_135331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012734">
        <property type="protein sequence ID" value="GIY56142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UE96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10852" checksum="DE81C70F2BFEEE19" modified="2024-11-27" version="1">MNSNTALVFDDVLINSNTTLVFDDALINSTALVSDDALINSNTALVFDDVLINSNTTLVSDDVLINSITALVFDDVCLDTVDHRNSIKSATMNILFIFSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UF15</accession>
    <name>A0AAV4UF15_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cortactin-binding protein-2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_667701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012766">
        <property type="protein sequence ID" value="GIY56403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UF15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050719">
        <property type="entry name" value="Cortactin-Actin_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019131">
        <property type="entry name" value="Cortactin-binding_p2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23166:SF5">
        <property type="entry name" value="CTTNBP2 N-TERMINAL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23166">
        <property type="entry name" value="FILAMIN/GPBP-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09727">
        <property type="entry name" value="CortBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cortactin-binding protein-2 N-terminal" evidence="4">
        <location>
            <begin position="35"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="354"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="447"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="115"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="250"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="552"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY56403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="636" mass="69620" checksum="5863B3722C6C733E" modified="2024-11-27" version="1">MAARNVTKTQPSALGGQFEQAEKTSSTLKRHPKMELSKPDLLQLLGVLEGELQAREIVIAVLKAEQVKQLLYPKRKSASANDPWAALQRDCLGAFDATFDETAVKNLYGMQLSQLENFLKQYKVAQTQLKQQLQEAEQRCEKLLSELEEEKRKHAQDTAQGDDVTYLLEKERERLHQENEFERQQNRCMEKDIKCLTETLEQERLRQKQIVLLLLAERKRLIFRYAEEKQKCDRLSQILCDEKGRIADMVDGLEEESKKSLQMEAELERQLCEFEIEREQFKADICSLESKNNELTLEVQRLQEELESQKLSASSNLSSQSQLGEGVRSTIVTMVSTPPIRAVPTISPTVSPPRGVARAVCPKTGPAPATPAKPPGLIPQAPAKIAPSKPVYSSSNAVLSPLCSPPLATSGLKSSSKPVKPSSPASLVSPSVLESIGSLLQVVPPGPQYAESPMSPPEGEKVISDSTSSNAKGYGTVKVSTSVPVHKAGTAAALNIANSKKPGIGRGAPPPIPPNKPVLPPQALHRKDTGSKPPVPPRSDVTPENTPEKNVQRCTVSSRFLNTAKATPEESPGSNTVEKDETQVGVSNEKNSTSIHAIASENKVESEVLVQELADFQQILVSMASNKIFNSVNDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJX1</accession>
    <name>A0AAV4UJX1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_118181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013022">
        <property type="protein sequence ID" value="GIY58151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJX1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="305" mass="33880" checksum="DBB0F96FCA371B66" modified="2024-11-27" version="1">MMEQAWNAPNEPASQQRQQNLSRPESQGARRRPIHEASQGVQPPITQRSQLNLPLSQPESRGAVKRSIHEASSQHGQHGILLPISQQRQQLNLPLSSQTKSPDTTNRSIHEALAQQAKRGFLPPISQQEQILSPTKKKKESTTIFKKITDKFCAVKVEPDPVKRSDQPSSRMPVQPQPSGSQQHVQSQPLPTQKVQQDPSATHSGLILSARQLLEDQQATEQRLSLSPPRVLQDQPMITSQPSTSLSPQRAQDQPIVATVQGCSLSLSPERVQETEASTSQPSRRPALFRKKKKEKKSKELAPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UV14</accession>
    <name>A0AAV4UV14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_95461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013502">
        <property type="protein sequence ID" value="GIY61697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UV14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11278" checksum="01953D02C903A572" modified="2024-11-27" version="1">MGCSGLAAEMLPEQFSLLTMQPGTMRDYFSPHHINVPFIVFKKNGDEVGWPSSQFETNISKCDIWASFRTFLYSSSPMVGHSDFQIYHAPHSAREISRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UW68</accession>
    <name>A0AAV4UW68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_90151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013559">
        <property type="protein sequence ID" value="GIY61973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UW68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10399" checksum="231D921556671B28" modified="2024-11-27" version="1">MSLHLRPHDFFSRGVTLLQMHKHLNPVTHASCLFTLPAFGFFCDSADCRAICKQGRPSRGCKNRAQMTSKNNGRAETTVIGWDFAMSGVEMKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZQ2</accession>
    <name>A0AAV4UZQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_285741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013746">
        <property type="protein sequence ID" value="GIY63460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9313" checksum="A28745AE4320B87A" modified="2024-11-27" version="1">MENLLQQERNRMRNQTSGGISSPVGQMGWAFRLSSNTHREWKHRERITPSLPFHQTIASTQCTMPGLLEHEQKSESVVHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1S9</accession>
    <name>A0AAV4V1S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Programmed cell death protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Pdcd5</name>
        <name evidence="3" type="ORF">CEXT_514261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013789">
        <property type="protein sequence ID" value="GIY63839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="entry name" value="PDCD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY63839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14428" checksum="94E0C99BE2FA1A9B" modified="2024-11-27" version="1">MDDEELQALRAKRLQELQAQRGHGGQPNEAAAAEQKAKEEEFKNTILTQVLSKEARSRLSTISIAKPENGKMLENMIINMARTGQIRSQLADNEFVHLLEEVNRQIKQNTPTVKFDRRRAAVDSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V912</accession>
    <name>A0AAV4V912_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_6871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014111">
        <property type="protein sequence ID" value="GIY66389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V912"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17415" checksum="0AFEF4063876037A" modified="2024-11-27" version="1">MCYVVLKILENSSHESKKIFSSRSRTFLPSRSPLIPSISPLFDQENDNHVVWETGSHVTILEKITKRTNRMSYLSKKEASVTELTGRLLILGFCRKPPLRFGNYQFLGLLQDEWQHQLTPKELEKQTLFFVLPSPMLLSPILSNISQPTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBB9</accession>
    <name>A0AAV4VBB9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_513321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014223">
        <property type="protein sequence ID" value="GIY67299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBB9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12794" checksum="BBEBCDF61C311C91" modified="2024-11-27" version="1">MLFLQTNRASIVYEDANFSFLFNYHLKSVRGDILFYLAFLVCHDVSADDLIRTTCLSFQGFVSEVLNYRRWQWVCNCDDGRPILTNTVCLVFYSLLLPVKSILSSECSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VH05</accession>
    <name>A0AAV4VH05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein-tyrosine sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Tango13_1</name>
        <name evidence="1" type="ORF">CEXT_718011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014557">
        <property type="protein sequence ID" value="GIY69622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VH05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12893" checksum="A9567C1B733CDD8E" modified="2024-11-27" version="1">MLSALGYDPRANPPNYGQPDSLVIKNTFDLKVNKKVWEARERQVVEKRESIWRSWLQKTPRTKTGISTTVAIAENSTEFNTNMSQNNNSGWYMVRKVGGINENDDDQEIRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VH78</accession>
    <name>A0AAV4VH78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_343291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014518">
        <property type="protein sequence ID" value="GIY69305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VH78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="16891" checksum="C5BDFF8353FFBC54" modified="2024-11-27" version="1">MGENDSLPSTISLRVNFPPPLQDLRLSPGREGQEQSEDRHEKPLPDRKKGAAASVTCLETLPTGRAGKEYSSLRQHKMKSPTRIERRVHQITSTSSWRAGSKEVSTEKGLFEGEGRSYFSLFLARKLIEKKKQQGRGYKGIWGQCDADFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VT89</accession>
    <name>A0AAV4VT89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DDE_3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_98252_1</name>
        <name evidence="1" type="ORF">CEXT_107371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015017">
        <property type="protein sequence ID" value="GIY72989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VT89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17079" checksum="51DA21FC9939C929" modified="2024-11-27" version="1">MDITPKKRTGIVILSQHTSMTLRDIAAAIGVGKFRFRRFVRRNTGEHIREQHLNQTVKHHQKQRFGGYFTSDGPGSVVPVEGMIDSQDKILPFMETFAGGNGVFKQDLAPCHTNKLTTKYLQGKKLTILDSPGNSPGVNSLENLWSIVKRCVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VW84</accession>
    <name>A0AAV4VW84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dystrobrevin alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Dtna</name>
        <name evidence="8" type="ORF">CEXT_710021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015117">
        <property type="protein sequence ID" value="GIY73728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VW84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010646">
        <property type="term" value="P:regulation of cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023051">
        <property type="term" value="P:regulation of signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099536">
        <property type="term" value="P:synaptic signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02334">
        <property type="entry name" value="ZZ_dystrophin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050774">
        <property type="entry name" value="KCMF1/Dystrophin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12268:SF27">
        <property type="entry name" value="DYSTROBREVIN, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12268">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE KCMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="7">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="279"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="200"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY73728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="441" mass="49478" checksum="6A666BFB346722BC" modified="2024-11-27" version="1">MSDPAPPCLVWLPLLHRLASVENVLHPVQCDGCNREAFLGFRYRCQKCYNYQLCQDCFWRGRVSGSHTSQHEMKEYTYYKSPSKQLGHSLKKSFRCVPEKQASSIPRFPEEPEKTLNLQHIVPPSPIPSHNGFHSVANNSFDMSSLDGRSTTRSLESNRGDDEHRLIARYAARLADTRSTMRSPSDLSLNMDTTRQRDLIAQLESKNREIMREIVRLRKQQEQEDAVLQNEQNPTLLNELRALRQRKERIRESFIYPSRESKRTDGSVGSLDENAQGLILKPTGNHQTSPRSTPNSSPRSATSKSPPLSTPYPVSSSRSAPTTPDTNPPTSESSGGVPNNAMAAYDQSGSTRSLRNDLLVAADSVTNAMSSLVRELNSGSEDEDGNCDSKVLSSSRDFETEEESAVESLEGGVTLWRDERQRAQENHFLKRNSSPEQFSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6L0</accession>
    <name>A0AAV4W6L0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_306101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015636">
        <property type="protein sequence ID" value="GIY77494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6L0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9105" checksum="3095A70EA6B587AF" modified="2024-11-27" version="1">MYSFGAIRRLFDEFIYTCMVAEGETEEAAMRGECRSTKELSQCFIGQQLGGQLKIVFLEEFVDDIEDYLGQGWANYVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7J1</accession>
    <name>A0AAV4W7J1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_151151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015611">
        <property type="protein sequence ID" value="GIY77355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10215" checksum="00D2BB862628E3EA" modified="2024-11-27" version="1">MSKPLQTKSLKRTGPMYCAITQIFNIRCNDRLQHHTISREPQQQIWRTKNVLLNYSEKGFGPQISFEQRNLEARRCVSGGYELARVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W841</accession>
    <name>A0AAV4W841_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_741761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015752">
        <property type="protein sequence ID" value="GIY78384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W841"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="10813" checksum="0618D52769346040" modified="2024-11-27" version="1">MSTSAAVFFHCVELPSSSISRTFHPSSPIAATSSTSSCNTLCSCHLLLRATFSTANVFHCCRRLPLLPTSSTESHLLQPTSSSTSCDFLCCCHRLSLLPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBL5</accession>
    <name>A0AAV4WBL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_609981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015940">
        <property type="protein sequence ID" value="GIY79886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15574" checksum="76E6CC562D6320A9" modified="2024-11-27" version="1">MATAFILSVFPNQPSIPVSLLVPHLCGILAICSFPLRHVLVGLHLITNSGCYKVGKTSTGNVKCCSNAHELGQWPPRGPKLDILSATAPSHSCCSSASHKYGKPLVIYFYLSAREVSVELKTHKSSTRKNEITLPILLRSFQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDS5</accession>
    <name>A0AAV4WDS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_160961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015890">
        <property type="protein sequence ID" value="GIY79455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9998" checksum="5B1638065FB2D2BA" modified="2024-11-27" version="1">MNARLETGLRHGSRKDSPKLKTIQLGKRPKKDAKSAGREKDRCRQTRCPDAVSLLTSAREGAPGCDEEQMLEMMITLSANMGAVELKLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WH62</accession>
    <name>A0AAV4WH62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_683471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016104">
        <property type="protein sequence ID" value="GIY81301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WH62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="20223" checksum="065683E247A0B43E" modified="2024-11-27" version="1">MIDRFTERIEACSITAESADKRRHRTIKASLKCHLQQNKSWVDALPFVLHGLHSALKEDISYSSAELLYVEFSVSWQYLYRDGDPIYDKSKIVDRELGFKTENYNTLADEMMNLDQRVLRLGSRKQEWHSSGKSFQSMEQLGCSAAYLSRRMHPEIFNYTLDFRTQGAHFETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WII6</accession>
    <name>A0AAV4WII6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Adhesion G-protein coupled receptor G2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ADGRG2</name>
        <name evidence="9" type="ORF">CEXT_237341</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016204">
        <property type="protein sequence ID" value="GIY82044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WII6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053066">
        <property type="entry name" value="ADGR_G7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057244">
        <property type="entry name" value="GAIN_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046338">
        <property type="entry name" value="GAIN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000203">
        <property type="entry name" value="GPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47767">
        <property type="entry name" value="ADHESION G PROTEIN-COUPLED RECEPTOR G7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47767:SF1">
        <property type="entry name" value="ADHESION G PROTEIN-COUPLED RECEPTOR G7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01825">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00303">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50221">
        <property type="entry name" value="GAIN_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="585"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="654"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="697"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="742"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="771"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="GAIN-B" evidence="7">
        <location>
            <begin position="377"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="8">
        <location>
            <begin position="549"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY82044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="833" mass="95792" checksum="F65F63CD64ABF541" modified="2024-11-27" version="1" fragment="single">ETTEITESTWMLDSSLGFEVNIPVLTCRTKYKEYSEVKWYKDYALLKKGGVGLSDHILSLIDLLRNDSSVYFDNPLKLQGYYWCETNYINSSVVFRYLFRITDELQDVLFDFLPKPNTYVTDIIERKSGLEVRFYLFVQTVVHPRTPYDRDLVEDQHELEFIFDYLNNETISVHQTHYHQILKWTNSKGINIHEIRLYSTLGCYQDTTLVPGEPPKEITWPFANIGEVVIPVEAWSSKNGLAVTRLCTGSFYGGAHWGNPSSKPNMPPSKLTSELKNLYNKFGDDPKPVYIQNLQQLTDRPVHLSVTDIHIVLDILTELSKVKELTPEEIDETFTVINNIAETNRSELIAAKGTIKFTSRLLKVIDNVLLYAKEKNKEVTLTKKELLVDIKYTKVPTDPKDHIIGMAVLPSKVGDKRENELPSNYPCRINLALFRDWVLFPKPMEVLHKRNYKVIPTLVMYVSLSGGPAWNLTSPIHLYFKDTHGKKIENPVCSHFDPRVDDHNGGWNTEGCEYGGMKDGFHICRCQHLSIFAVILSEKYDTSSEQFRLGTAIYVGCAVSIIALSFTVVLYLLSKVWRSTVDHSVLFWLALSLLCCLILLFISEMNFLWKPGCLLMAMLLHYTILVVFGWLLVQAVMNRLRFANKSDIEEIPHFILKSALSVWCVPIIIMIIIWITIDYVHHGEETCLKTVSDVSRAAVIPIVIVIFITLCLNVCAIYAVSCRFKKDFLIGNHIYDNSVVKFRVAVTIFFFLCFLTWLFGFFAVNEKSNELRILFSISVTLTSYYVALFFIFHEISFWEMCGKGKRNDEPKSEVVKYVAEKSVEDDEQTQQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WL82</accession>
    <name>A0AAV4WL82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_548371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016334">
        <property type="protein sequence ID" value="GIY83078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WL82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8924" checksum="DC65F2985B1F9A6C" modified="2024-11-27" version="1">MELSSPRRVKSTEATGFFPPHCSDEPNCSLVFRDTISPRSDGTGQGFEPKDVKDHKQKTHRQRYFEIMVWLITSLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPM1</accession>
    <name>A0AAV4WPM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_54351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016429">
        <property type="protein sequence ID" value="GIY83789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="201" mass="23370" checksum="A98E3632A1955A33" modified="2024-11-27" version="1">MGSTADAVFRRDELCTNATIILDSNPLVGSLQTLFSENRITQLCNYYLRFESSCGFYCSRCFKKCSDYACVKVLSEIRNHLWALLQSQFSDVTRLCNYYLRLESTYSIAAAVLRNLDYARMQLLSGIRIHLWALLQSLFSSMTRLCNYYLRFESTLWALLQSLFSNMTRLCNYNLRLESTCGFYCRRCFLKIGLCTYATII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WT45</accession>
    <name>A0AAV4WT45_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_109491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016615">
        <property type="protein sequence ID" value="GIY85111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WT45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7757" checksum="538CEB8851153158" modified="2024-11-27" version="1">MHISMASLLVSLVTSPKHTKSAIWKTTELELSENRWTCVWATDLSDQKLGHRRDPPQKSQKQKRDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUI5</accession>
    <name>A0AAV4WUI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transforming acidic coiled-coil-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tacc3</name>
        <name evidence="10" type="ORF">CEXT_292721</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TACC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016643">
        <property type="protein sequence ID" value="GIY85309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039915">
        <property type="entry name" value="TACC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007707">
        <property type="entry name" value="TACC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13924">
        <property type="entry name" value="TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13924:SF10">
        <property type="entry name" value="TRANSFORMING ACIDIC COILED-COIL PROTEIN, ISOFORM K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05010">
        <property type="entry name" value="TACC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transforming acidic coiled-coil-containing protein C-terminal" evidence="9">
        <location>
            <begin position="894"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="936"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="240"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="351"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY85309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1101" mass="122206" checksum="C82849DFE3EECE89" modified="2024-11-27" version="1">MGDASNTISYDENENRPANGRHNSDGNVVLGNNLTVIHSGPTDLGLHLSNAEDSFSSSYSNFFDKVESSNEAESFQSVNGSVLTETEIKHVSMPQNNENEIVNCSSTESEENIAIAKLVEDPNCSNSILLNPEITDNIQNNVNILESKEINHNSVVLEEDENNLCMSVTDLVDFSFKESETATNIPKDFPDFNSAFKYNDAITNFLQEMNANSSSKVPENLSKNSLEEMNMNSSSKVPENPSNNSLEEMNTNSSSKVPENPSNNSLEELDMNSSIKVPGNKSNNSLEEMNTNSSSKVPENKSNNSLEEMNANSSSKVPENKSNNSLEEMNTNSSSEVPENPSNNSFEELDMNSSIKVPGNKSNNSLEEMNTNSSSKVPENKSNNSLEEMNTNSSSKVPENPSNNSLEEMNTNSSSKVPENPSNNSLEEMNTNSSSKAPENPSNNSLEKNVTNLAYKMLENSTHDSHEESVIQFTNKMVKNSENNFGEIVCINSANKVSENQPNDLLNGTVPSLAYNMPENSINDYHEENGINSLYKVLENSPNFSPGQRVMSLAHNVSESSINNTCEKNDINSSYEIPESPVINVPQENVNNNSTCAEFENPTNNFEETVDANSAIKLAENTANASACISGVKTGNNLEENVTADFTSEKPIASESSTILEDLATVDPNVKESIKSINVPSKSAEKDLVFEQSENLNNDFIKSSNADAIFKIPDNLANNGAARISHEDFPFKVPDVPSDNTFKQLENMEFAFTLPENLPTNECDDEFSDAAQFFQDPSSFQFLENIRTSTVVPGPLIPRSSLYVNFDPLHSKFQSNALKSDNSELISTSLKETRISPDNSLNSGPEITNKNLADIAVRESVGNVLISFNSPQSSSKSGEREFVTLSPKKIYTEEELQQRLKLHELATQEAYLKKQREMELQFHKQQGLIKAQSSILEELLAVIIEFADDKKKLQEENTLLENEIKKLKEDLKTSTEDLQSVENTFADFHKRYEHCKVMLKSYKENEESLKQMNSDMQNKMKEQEEMYRMLQERAEEMLQKADAEVATIKRAGDAQVTVLKAQLKKAEMKISSLESDIKQIKLENNQLGGICDDLMAKVSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X910</accession>
    <name>A0AAV4X910_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositide phosphatase SAC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">INPP5F</name>
        <name evidence="3" type="ORF">CEXT_795561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017429">
        <property type="protein sequence ID" value="GIY91570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X910"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045334">
        <property type="term" value="C:clathrin-coated endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001135">
        <property type="term" value="P:regulation of endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034753">
        <property type="entry name" value="hSac2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022158">
        <property type="entry name" value="Inositol_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12456">
        <property type="entry name" value="hSac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51791">
        <property type="entry name" value="HSAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="1">
        <location>
            <begin position="96"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="HSac2" evidence="2">
        <location>
            <begin position="310"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY91570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="519" mass="60357" checksum="FFF9C364B5A0E5E5" modified="2024-11-27" version="1">MFTDTDSFYYSFTGDLTNSIQRQYYQSKDPEYKEKPLWKRIDDRFFWNKFMLSELISLQEPLCDPWIIPVIQGFVQIEQCWIDIIDDARISICRSGTKWKRKIINDAYLKHILEFSCPDLTYVSFDFHEYCRGMRFENVSVLIESIQDIIRDMRYCWTDSEGLICDQRGVFRVNCVDCLDRTNIVQTALAKTVMDIQFNKLGLLPPEGVLPAGCRRIFQMLWANNGDIISRQYSGTVALKGDYTRTGERRIAGMMKDGYHSANRYYMNRFKDAFRQATIDLMMGNPVTEDIHAVTPEREEADPESEINEQEHHERMKQLIEDCKKILIPDTEVVLGGWALIDADPVTGDPDKQDMDAILILTKDSYFVAEYDDQTDRIIKYQHVMLEDLERIELVSFSNKLNLFLRIVIYQPSLNLGPEPGVFKSKHYCLRLHYSVYGQSGYFHMFRSTNTRFFNNMAVPINSEEEAAESLKAICETFKVALSVKELNVPIFEGKLERRKSKMPLSQVGVRAGVFEATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XE75</accession>
    <name>A0AAV4XE75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_45811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017650">
        <property type="protein sequence ID" value="GIY93325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XE75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9495" checksum="C273ED083F6B78F6" modified="2024-11-27" version="1">MELGQYVKLRLHRRKQMQNSRQGHRQKTGCRKLLPSVYSLFHPGVIGIDSQPPDSGYLLWEPRMFHTNSIDEEFVVLEGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH67</accession>
    <name>A0AAV4XH67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_295131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017648">
        <property type="protein sequence ID" value="GIY93271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11274" checksum="666A12F9A2735337" modified="2024-11-27" version="1">MCTHIYICFSSSFRPEGGNDVLLISSLNQFEIEQKRKKRKTGTLSLSVPRTLKEHGVVNLPGTGKWRTENHLLKGSSFRESIPKRRVDERLRFNGKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLI9</accession>
    <name>A0AAV4XLI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_73171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000408">
        <property type="protein sequence ID" value="GIY94578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8589" checksum="CBD40BD7848D90FC" modified="2024-11-27" version="1">MGKQFHGQKTSMRGNRKCFPSNDTETPPKLRSFFGGFQEGGGGGKRSEGKKFPKDTIPRIQCLLSNGESRFVFGFVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNX5</accession>
    <name>A0AAV4XNX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_778681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000557">
        <property type="protein sequence ID" value="GIY95640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12215" checksum="5CD20AC9BBA7BC0B" modified="2024-11-27" version="1">MERTSLHEEAANMNDRASSWNEWKTVRDACPSIPGPSTLRYHLPGDNPKYSYKKNRFSASGKENYTYHTLKASTWCCSCSQTERTMHYFSGKIPRMVPGIDYSKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XV05</accession>
    <name>A0AAV4XV05_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyglutamine-binding protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Polyglutamine tract-binding protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PQBP1</name>
        <name evidence="17" type="ORF">CEXT_437411</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="14">Interacts with POU3F2/Brn-2, ATXN1, TXNL4A, HTT and AR. Interaction with ATXN1 correlates positively with the length of the polyglutamine tract. Interacts with RNA polymerase II large subunit in a phosphorylation-dependent manner. Forms a ternary complex with ATXN1 mutant and phosphorylated RNA polymerase II. Interacts (via C-terminus) with TXNL4A and CD2BP2. Interacts (via WW domain) with ATN1 and SF3B1, and may interact with additional splice factors. Interacts (via WW domain) with WBP11; Leading to reduce interaction between PQBP1 and TXNL4A. Interacts with CAPRIN1. Interacts with DDX1. Interacts with SFPQ. Interacts with KHSRP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic granule</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000979">
        <property type="protein sequence ID" value="GIY98862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XV05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000380">
        <property type="term" value="P:alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737">
        <property type="entry name" value="POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737:SF3">
        <property type="entry name" value="POLYGLUTAMINE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0391">Immunity</keyword>
    <keyword evidence="5" id="KW-0399">Innate immunity</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WW" evidence="16">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="157"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY98862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="285" mass="32790" checksum="EE0C1CB013AC5E4A" modified="2024-11-27" version="1">MPLPAALLARLQKRGIVQTTLPEVEEEVIAEDYDDNEKVEDNEENGVEAEETNELSESWIGCPNKWNIYHDCTPFCKENWGSGKDHPSPKTERRRLLMLKKYPVPDGWEEVYDPGIGRHYYWNTQTNEVSWLPPSHPKSKISVPAEKLRVLIKDTFLEPMDEGDDQEQDMSESEDDSEEEENEPINEEKERNEKRPRKELARERFRGRPKIRENDLDPMDPAAYSEAPRGTWSSGLDRKGEAKTGADTTASGPLYQMRPYPSPGAVLRLNAEIKNKSSDDEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWF2</accession>
    <name>A0AAV4XWF2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="4 13">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PDIA4</name>
        <name evidence="15" type="ORF">CEXT_626011</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4 13"/>
    <dbReference type="EMBL" id="BPLR01018423">
        <property type="protein sequence ID" value="GIY99471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02995">
        <property type="entry name" value="PDI_a_PDI_a'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000023">
        <property type="entry name" value="Protein disulfide-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000107">
        <property type="entry name" value="Protein disulfide-isomerase 5-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000027">
        <property type="entry name" value="protein disulfide-isomerase A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000076">
        <property type="entry name" value="Protein disulfide-isomerase A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005792">
        <property type="entry name" value="Prot_disulphide_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01130">
        <property type="entry name" value="ER_PDI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF210">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043106390" description="Protein disulfide-isomerase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="15"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="149"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="485"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="186"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="535"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605792-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY99471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="622" mass="71433" checksum="A6981F6FB4A377EB" modified="2024-11-27" version="1">MNYSFILCILVFYLTFPLNSASEDDIPVVEGDGGVIKTAIEDDVLVLTHDNFDIQVRTKDMILVEFYAPWCGHCKALEPEYARAAKILKQEEDPIFLAKVDATVETGLAERYEVTGFPTLYIFKKGEKIAYDGPRTALGIVEYMRERADPEWKPPPSVVIELTKENFHDTVKEADIILVEFYAPWCGHCKRLAPEYERAAKILNDLPTPIPLAKVNGIDEKELAEEFGTSGWPTLFVFRKGHKYAYEGPRDEPGIVSYMKDQAKPPSQVSDSYKHLKNTLGKIDATVVGFFNPDSEDFYQNFIEAANSLRGKFTFVHTFKKDVRKQFGYKDPTIVLFLPDIYATDYEPKKHHLYNAQATSSEIIEFIQKFSLPLVGQRSRKNQWKYSDKFPLVVVYYDVDFSFDHRVQTQLIRKEVAKVAKDYKGKITFAISNENEYEDELQTLNLDDSGEDVNVGFFDVQNVKYRMEPVEDFSEDELKTFVEDVLAGQFPRHIKSQPVPKENKGPVVTVVGSTFQELVMKNKKNVFIEFYAPWCGHCKKLEPIYKKLGKIFVDNDNIIIAKIDATSNDYPSEFQVKGFPTIFYVPAKDKFNPISYEGERNLKEMSKFINEQLSKTDTKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWV2</accession>
    <name>A0AAV4XWV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_95911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001071">
        <property type="protein sequence ID" value="GIY99621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8728" checksum="9467656F8FB13C47" modified="2024-11-27" version="1">MCQKHSAHARSGFGTSHPTRRNYSSDFLIVGNAWHTVRGSNTLRQKADRFHRLAFQGHLIPALVFHSDPQEFRIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXN9</accession>
    <name>A0AAV4XXN9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transposase IS30-like HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_241851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018363">
        <property type="protein sequence ID" value="GIY98960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase IS30-like HTH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY98960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9923" checksum="A5C0ED592976EB0B" modified="2024-11-27" version="1">MDLKGKEITPEERKIIIKLRNEGKTLREIGKIVGRTHSSIQRVINNYTSSKSIISKPRSGRPSKLTAREQRYVFKSIRLNPRISAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0A2</accession>
    <name>A0AAV4Y0A2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_498901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018559">
        <property type="protein sequence ID" value="GIZ00558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10988" checksum="9F9101774CDAF737" modified="2024-11-27" version="1" fragment="single">GQRIPENSLTRDTFLPESTPAPFSRIVLVTHRLVRNVPPSRFFPSPDTIFRNDFSVLSYKTPEILPGLLRLMVGDHEMTETPGRKLGKCTEGECFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y369</accession>
    <name>A0AAV4Y369_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_717961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001349">
        <property type="protein sequence ID" value="GIZ01787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y369"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043629819" evidence="1">
        <location>
            <begin position="21"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14019" checksum="60510B49865844F7" modified="2024-11-27" version="1">MLCTIITFFNILYIINTAISKEIINKPVSLENFKLIIIKTGTPTVDELLVLPTTEQIRITDNYLKPTVIFNQYPTPNNYTAPQKIPNITVEFRNPTVDELLTYPTLEQFQHKHKILKPTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4B5</accession>
    <name>A0AAV4Y4B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_770091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001235">
        <property type="protein sequence ID" value="GIZ00999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7990" checksum="E05D673459FB4D4A" modified="2024-11-27" version="1">MAQNGDRARGLGEGLALFLFSGDDDADDRLARQKEEDPACHGQVSAHFNRQQPPTLIFSRHFKVYFAPPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y545</accession>
    <name>A0AAV4Y545_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_89302_1</name>
        <name evidence="7" type="ORF">CEXT_176641</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001420">
        <property type="protein sequence ID" value="GIZ02238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y545"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="332"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ02238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="386" mass="43583" checksum="DB4EEDFCB36CBB6C" modified="2024-11-27" version="1">MATGNIDYSFPKRPQEFSGPFNLNYIDTVLETPYLVYSSESPSNIMDDNPCADEELPGQVLDTQNHNYPTATSSNDNGNSKNTFASSKEMDSPRVLADLMKMNKNDSQVMVQQEPQSSAISEHLNIRTHNVIPEELSIDIGADEDGTHSWRPNLTNSLSTDIFLTQPLFSKSPTTIALHPDEPDCSIPGNSIEEKLLDNVGRIRISDNPYLINNFHIDIKGHLCSQKAQMNIVKYEVMSGRRSITELTEAIQKLTYKLGEKKMFQNSQEIQKLSEENAQLRLECQCLSPLGEVDEKFYGASSTQNNQAEAHCPVINQCTNRSENIDIEYQDESNEWECPKCTFANHPAIQSCEMCHMTRPKKENPMFLSPMPETCYCHPENNREAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBH3</accession>
    <name>A0AAV4YBH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional activator cubitus interruptus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ci</name>
        <name evidence="1" type="ORF">CEXT_548531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018964">
        <property type="protein sequence ID" value="GIZ03517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18605" checksum="A09B5600AE2F7331" modified="2024-11-27" version="1">MHSPPMDNRCSTANCGDSQMMHAPPVYCNYQQVNQFPNQQTGYKCSQTCDASSTMQPHCHQIQPNYNMHHQHPPPNPPCFHQYHQCVNCGAGQNLPQNHCFANVQSRNTPQFISNNQVAQCMQQPPISSNLVDNFALKRLFYLKLKKLTLKSNLMLYLKQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCR6</accession>
    <name>A0AAV4YCR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CEXT_740431</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019190">
        <property type="protein sequence ID" value="GIZ05007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005272">
        <property type="term" value="F:sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIZ05007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10295" checksum="8340B4654A0C830E" modified="2024-11-27" version="1">MRNRQKPCRSETAWHFEWDVTVISHVPRYGMWELFSYIGGLIGCWLGISVWAFVDIIEGNCRRLLRLIQKLKQKSKNKLQVVFDLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFZ1</accession>
    <name>A0AAV4YFZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_456091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019232">
        <property type="protein sequence ID" value="GIZ05189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9867" checksum="3743C359D462671F" modified="2024-11-27" version="1">MNHSELLPHHTRSPWVAEASTGLRRKRKLIARIFEEKTRQEWQSLAALNIFTPRLELNGKIFRFLQIYVSTLNRHENMLRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M582</accession>
    <name>A0AAV4M582_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_295681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001844">
        <property type="protein sequence ID" value="GIX67017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M582"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12930" checksum="30C0EDEEAF9B6255" modified="2024-11-27" version="1">MEGEARLTSLLGGDTFPSLPRGLRLNKIVGDCKLKYGEGVDNKMTSGPIRACFPIRQFCIRRVLNHGDVVFFEVETQAPRVLSRVECRYSDISISLPPTHAIPAPGLSGLQIYPYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5Q8</accession>
    <name>A0AAV4M5Q8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_384991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019398">
        <property type="protein sequence ID" value="GIX67427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5Q8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12701" checksum="F3ACC9A786B560C5" modified="2024-11-27" version="1">MIHGEDGIGLLDKNNKTTPANPSFLEKMTSLFTFTETHLLNIFFDGFQISRMWHDRIHGQVYIFQRAPFFPTPIRYISLYVSTKPSAEVHPIFLKENRKAQIQSGYHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBT3</accession>
    <name>A0AAV4MBT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_302501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002020">
        <property type="protein sequence ID" value="GIX69162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13730" checksum="65DC17F1617C4C31" modified="2024-11-27" version="1">MRESNIQQRDIYTERHQHRETSEHAEWLSLHQIQLNSNMKFSHVTNDAGIIGERLREQGKPSNSLVQFLHGCIKAGSRLTAQQWRVGKTISFSVLLLFVDLKETRKDLRGGFQKILFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBW0</accession>
    <name>A0AAV4MBW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epsilon-sarcoglycan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SGCE</name>
        <name evidence="4" type="ORF">CEXT_13981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002100">
        <property type="protein sequence ID" value="GIX69967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016012">
        <property type="term" value="C:sarcoglycan complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008908">
        <property type="entry name" value="Sarcoglycan_alpha/epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048347">
        <property type="entry name" value="Sarcoglycan_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048346">
        <property type="entry name" value="Sarcoglycan_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10132">
        <property type="entry name" value="ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10132:SF14">
        <property type="entry name" value="SARCOGLYCAN ALPHA, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05510">
        <property type="entry name" value="Sarcoglycan_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20989">
        <property type="entry name" value="Sarcoglycan_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Sarcoglycan alpha/epsilon N-terminal" evidence="2">
        <location>
            <begin position="30"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sarcoglycan alpha/epsilon second" evidence="3">
        <location>
            <begin position="103"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX69967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="248" mass="28344" checksum="4325AB35F29D0567" modified="2024-11-27" version="1">MSKFAKPVTVFSTEAFFIPISYEWFQKFRKDDPLEYSASLLDMPDLPNWMFSHPTNSSNAFLYGSAEEAGNVKIEIIALNRNTYDTATTILELIVKPRERIFQYEVEMKFLNLNVDDMFRSGRLDRLVEVFQNSLWKGNDDIYITKVVSSLDAGGRLPLNPKMKEGVVVRIGGAAVFSRDLEDLEREFNPCEIGYHVLGIIKELQLNIYFEAEILLLIGAVSVFCLINAKRILDQVMVGLIIHILPYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFC4</accession>
    <name>A0AAV4MFC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_228150_1</name>
        <name evidence="2" type="ORF">CEXT_659891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002060">
        <property type="protein sequence ID" value="GIX69524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043842515" evidence="1">
        <location>
            <begin position="18"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16758" checksum="BAFF0E2A857BC99C" modified="2024-11-27" version="1">MANRHCWIFSIFHGSLAEFQVIGKGLRPILLDSLSFGRERALIPRKQYGFKKGHGTSYRILYFGQRVRDAQDHKPIPHTIAAFLDMSKAFNTVLGQKLITKFYDSFGIKEKALSCLSDFLKDRIFKVMYKNPLSDKFSLKQSIHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIJ8</accession>
    <name>A0AAV4MIJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_36791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019790">
        <property type="protein sequence ID" value="GIX71809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11364" checksum="8FC5AEDC3E367DBB" modified="2024-11-27" version="1">MKKFKTKENCRKAIDAPIFRRKTIDLYEMKQENEMYNDMQSSNKNIAAGEANEDASNLDQCDIEINMKIECSDFTEVPLNSTDIISKDKKKRKKRHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJ63</accession>
    <name>A0AAV4MJ63_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_765461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019839">
        <property type="protein sequence ID" value="GIX72340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJ63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8251" checksum="CC083A3F04E0FBBA" modified="2024-11-27" version="1">MRLHRPHLFGTRSGLWYHRPHLCSFGRRIAFQSHGCEFDFDPTIELATMGLDDRFRQMVDQIFPDLRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUK9</accession>
    <name>A0AAV4MUK9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_337101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020079">
        <property type="protein sequence ID" value="GIX74594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11436" checksum="9E1A4FC5C165FAA5" modified="2024-11-27" version="1">MVSWCRISSVLSPLDLVSVCCLWSFLDVWRQGKWRLAAEGPASAYANGGRIATCVCPRFHFQIRFTRNVLIYIRRIIPVGLNRGGLSRNGSVIASDGVVLRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVI1</accession>
    <name>A0AAV4MVI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_806211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020257">
        <property type="protein sequence ID" value="GIX76495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005918">
        <property type="term" value="C:septate junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035151">
        <property type="term" value="P:regulation of tube size, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019991">
        <property type="term" value="P:septate junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004031">
        <property type="entry name" value="PMP22/EMP/MP20/Claudin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284">
        <property type="entry name" value="EG:80H7.2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284:SF12">
        <property type="entry name" value="EG:80H7.2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13903">
        <property type="entry name" value="Claudin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX76495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="218" mass="25813" checksum="6A671C75A6CF0BC3" modified="2024-11-27" version="1">MVETPPPKARSSWYLLIGGIFAFLASLILFISFCSPYWLESYPETYSEFVRMGLWNFCFRNYRHPSYQYDELFDGCHWVFSYKYQNIRDWMQPAWLIFVQAVMSLSIIFALLSLSCISIILMRFLLKLEVFFIGAAFVFEAIISVIMFLGVSVFGGMCYNRSWLQYPSFNHLSWAYGLAVVSMFFHMFAAAYLYADTKRAQDYRRRTSNLVYNMHPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYZ0</accession>
    <name>A0AAV4MYZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_465431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002783">
        <property type="protein sequence ID" value="GIX77695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15624" checksum="3FD56A9C7FC9F5DC" modified="2024-11-27" version="1" fragment="single">NQPLCCSRPTSINLSHNLLTSLGSALSYSHVKHFSMKHNLIAHLGPGDILSVPGCRSSLCRERHLTDGAPHLLSTSGRPSGIRAGRVLQHQNADSALSGRKPDNHAGIEVYALVKSPRSADQQQPNPETYTPVKFRLNSRIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZP8</accession>
    <name>A0AAV4MZP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_160671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002801">
        <property type="protein sequence ID" value="GIX77911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14100" checksum="D5AF258B5A026360" modified="2024-11-27" version="1">MAGFHETNGNGHFLCDFGFDADFIGRNRSNIYGYVSPTFVTSFEMAGSIPDRPGVSSFQSVEPCWNFTTLFFVVVAVVVFFHFTEIVEPGGGQSFSLKVVALFFSFFCNRCCICWNIDQKSFTGHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3D6</accession>
    <name>A0AAV4N3D6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_43461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020481">
        <property type="protein sequence ID" value="GIX79330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3D6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9629" checksum="313422FCE81983D0" modified="2024-11-27" version="1">MGGFEKIPSMERRTKGTKKKKNRLNEKRGGFEPYFRWEGPLQISSRRFARWTGVHDGYSDLSDAILILLRQHHVEGRGGRGWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6F7</accession>
    <name>A0AAV4N6F7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_751471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020581">
        <property type="protein sequence ID" value="GIX80293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6F7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12960" checksum="F0E6C0058E0A141D" modified="2024-11-27" version="1">MHRQVLRTGVRRWTAVRCICPRQLSSHVVNSLLPVHDEFISRHIGPRERDQDVMLKELGFKVSPRGFTWVSKLLLSLWIRALGFCWISGVGSACDPSRSVLTNPNDLAGHFGNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N842</accession>
    <name>A0AAV4N842_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_571281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003001">
        <property type="protein sequence ID" value="GIX80118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N842"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20068" checksum="CE59E8F37799181A" modified="2024-11-27" version="1">MHSGEYFDEMPAEAFSDCSDAKMTGGDRMDIIIGSLQSHDGEPMYSVKTDIPEVRLGVTEEEIKRIMSTNFKLGKRNCSVNNVNTNTKRNTKTGKEANVVKRAGNSIIKPTKLINISQDGFIQPGRKQTAKTKDGHVPFRIPINNKFNNIEEETNSQEQSQDINQHLQKLPPLMLAFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9U6</accession>
    <name>A0AAV4N9U6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_172974_1</name>
        <name evidence="5" type="ORF">CEXT_333611</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IL-17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020691">
        <property type="protein sequence ID" value="GIX81594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010345">
        <property type="entry name" value="IL-17_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06083">
        <property type="entry name" value="IL17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX81594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11888" checksum="0297419DBFC5CAF9" modified="2024-11-27" version="1">MGPNEDVAERAMCPFKWMVSNRNPSRIPEYLYEAQCACQISRLTSRVASCIQLKAKIRVLWRVSCEGPLHVYKEGWEEISVACVPVGLPIISSKKAHVVQYLPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBK3</accession>
    <name>A0AAV4NBK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_731821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020721">
        <property type="protein sequence ID" value="GIX81863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20673" checksum="3C8EE00A41B70B4F" modified="2024-11-27" version="1">MMMILRSRVWEQLKLINDSKDEKQLRLSGHSFPHSFGRLRINILSQDTTRALKRYLRAIYEGWVVNLMKNVTTLTANWSVKTKDEKQLKHSNHSFPHPFGRLRINILSQDTTRALKLNAQLKENFIIRVHGNYIVRDPGFCFTSAEGSENYDVELRISFAIIWMLFCWLDLDSFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NC27</accession>
    <name>A0AAV4NC27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_453561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003220">
        <property type="protein sequence ID" value="GIX82277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NC27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18817" checksum="75CA4D22110060E4" modified="2024-11-27" version="1">MKQAGVKHKHEEVKLYMKNMKQVGVKLYMKQVGVKLYMKQVGVKLYMKLYMKQVGSKSEERLFTRKLLLLLQQTERPKNPCFNTAKEGLIIGFPPGNISGDDDLNPDTAIIPLKGESITYDSPAKQWEDTLQKVTRLHLTPTEGWKDCSISNIPESKGESAFDAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDR5</accession>
    <name>A0AAV4NDR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleic-acid-binding protein from transposon X-element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ORF1_105</name>
        <name evidence="2" type="ORF">CEXT_143571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020748">
        <property type="protein sequence ID" value="GIX82101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF2">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="90"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21400" checksum="634D54E4E2B2E8A2" modified="2024-11-27" version="1">MDEVIEFVSDYDIDLLLIHETCLQPGHEPKIPNFTLYKNDRINYTNLRTTGGTCIYVKNSLNHHQLPTPQMTGIEATIVNLQVTENTKIAFASTYCKHSATFAINDLSKLLNIQPHVIVAGDFNAKHTSWHNTSNSARDINLNKHIKNRSDTKIIAPTEYTHLNTKNPANNTIIVFALYKNIRFRLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDS9</accession>
    <name>A0AAV4NDS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_628891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020749">
        <property type="protein sequence ID" value="GIX82116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13071" checksum="6C15B330DFD6DCB2" modified="2024-11-27" version="1">MKPLSIPLCQLPLQDLWSKLLHRIKGGRDLLTTEVDAHPLWNHSSPLPSVRMSWNHSSVIKPLFEHSLPIQTTPFPQAGGHSTFRRRDTSCPVLKGVGGIFSSRPPHPLFQILKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGH3</accession>
    <name>A0AAV4NGH3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">c-Myc-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_10244_1</name>
        <name evidence="5" type="ORF">CEXT_509811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AMY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020815">
        <property type="protein sequence ID" value="GIX82811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026060">
        <property type="entry name" value="AMY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13168">
        <property type="entry name" value="ASSOCIATE OF C-MYC AMY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13168:SF0">
        <property type="entry name" value="C-MYC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02028">
        <property type="entry name" value="CMYCBINDINGP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX82811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12598" checksum="6A2BB4C87C75820E" modified="2024-11-27" version="1">MSVSPDIQTLCQNKSQVAPTIDSEREEFRKYLESSGVLDVLTRAMKDLYEKESKPDDPLSFLTSALGAISFDAKETALLQDELRNLKLLMKKLEEENRFLKEKLEKITSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGJ5</accession>
    <name>A0AAV4NGJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription termination factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TTF2</name>
        <name evidence="5" type="ORF">CEXT_812711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020915">
        <property type="protein sequence ID" value="GIX83932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX83932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11988" checksum="802B2F32F0E17AB8" modified="2024-11-27" version="1">MPSGGILADDMGLGKTLTMISLILKQKEENNYLAENSNCSTHATLIVCLASIIHQWNEEISKHCKTNSLQVLLYHGSKREKDIEDMKDYDVVLTTYNILLSERKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIQ9</accession>
    <name>A0AAV4NIQ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_683511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003326">
        <property type="protein sequence ID" value="GIX83354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="12240" checksum="149BDC77C7BD6AF9" modified="2024-11-27" version="1">MPSSIDKVTSFKKSSAERLAARNEVPNKEFSCSPSTPIQRWVEKYNRIRAIKQHYLTGRMRIFVPHLCRVGENAETLAKQWNSLYEVSGTIISSVNSFYKNTERKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRX7</accession>
    <name>A0AAV4NRX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ homolog subfamily C member 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DNAJC12</name>
        <name evidence="3" type="ORF">CEXT_178091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003689">
        <property type="protein sequence ID" value="GIX87549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029827">
        <property type="entry name" value="JDP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44500">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44500:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX87549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14886" checksum="9A8F73483C76F5E1" modified="2024-11-27" version="1">MTDDDDFYILLGCDESSSIEQILAEYKILSLKYHPDKNPGDPNAVSRFQKLKKAKEILTDPENAVSAHTSVHWTCKKQKDLMLENACNVGEPSCIVQEEETNEKDFCKCKAWERDPANEVLRKFRNYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSP0</accession>
    <name>A0AAV4NSP0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ionotropic glutamate receptor C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_9847_1</name>
        <name evidence="5" type="ORF">CEXT_254601</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003633">
        <property type="protein sequence ID" value="GIX86946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043618620" description="Ionotropic glutamate receptor C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX86946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="24159" checksum="EDC10E1B5B860436" modified="2024-11-27" version="1">MLICLILMPLLFLLLLSMKHSYSHVQLILLGALLRQPMRASNTSTIYRILTSSWLIFALIASFSYSAVFLSLLTVPPEIPVVRNFKELSEAVLKENYKCFVPRGSTVLDILAKHEKEYLRILGQVAIERGWYLSGHPLTQSPQIGARSAIVTTRTLLQIVAGSEEWKNNFCLKTLSQNLNFAIPMRKGFLPQSKTEYISFSFEQRRFVQTDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWT1</accession>
    <name>A0AAV4NWT1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_311281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021367">
        <property type="protein sequence ID" value="GIX88864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11678" checksum="C5DDC9E3DD5FA788" modified="2024-11-27" version="1">MEGRGRQYDYRFNWSRERPIARLARAGCQSSGEGRVEVALQANRKRIREKGKSIRDACQRGSLFNKGNGPLYCDASRVCHTRVLFTLTFKILEVSEGYVTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZ42</accession>
    <name>A0AAV4NZ42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_525051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021382">
        <property type="protein sequence ID" value="GIX89015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZ42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="10836" checksum="23924B1FDF19BBF8" modified="2024-11-27" version="1">MQQAQYGPPQPSPTQQQQIPQQVRGSPFGGPPGSGPSQGQTGAPSPYQGPPTSQAFQGQMQYPAGYSPGPTTGTGPVPSGPSPANPYSRGSTAGYTRPTLNYPTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1T2</accession>
    <name>A0AAV4P1T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_392151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021467">
        <property type="protein sequence ID" value="GIX89988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10804" checksum="1A410243591B2C29" modified="2024-11-27" version="1">MVSIGIEDSSSCVFLNHRGNQVETIRRQQYLPDVLEAMAVVKLGVTKHEREERKSSGTKRLTILEPDLWCLRRKAAPPSGNENICKPQKVTGDQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5I9</accession>
    <name>A0AAV4P5I9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_387051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004114">
        <property type="protein sequence ID" value="GIX92289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16277" checksum="C5DACFC7B7F0110B" modified="2024-11-27" version="1">MSEEEKLKVHPEPIEKNRRIRGSLRTNVTKLIKKIDKELASANLNSDSLQESLTILFEREQKLGNSDDIIIFQSPDAEMENSLEYSEQIIKYKSRVNRYLSESVQVDKNEINKVPVVASEIKKDCNTKLPELIWRSLMGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5M1</accession>
    <name>A0AAV4P5M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_264511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004134">
        <property type="protein sequence ID" value="GIX92527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11380" checksum="1D783E3C65BCAC6B" modified="2024-11-27" version="1">MSKFGKNIQLSPTVLKKSIPVLDGKPLLDYPERTVLYSCSLPRGRTHLVLDPHAIRCCEVLQNSRLFPRVWKLLFLLSQVGSLVLETDRLVEEKDFMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAB5</accession>
    <name>A0AAV4PAB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_574201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004266">
        <property type="protein sequence ID" value="GIX93559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9230" checksum="2FD649B1BA410831" modified="2024-11-27" version="1">MVRLRSGAAGSNSIVATFPFRNAFGQTFPKLCSFNCVCVMVGRLLPIYLFLAADMALMQLPQLALLPFLRNFDEPSDKSSYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAY3</accession>
    <name>A0AAV4PAY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_314041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004351">
        <property type="protein sequence ID" value="GIX94246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11598" checksum="794F0111DCFD2CC0" modified="2024-11-27" version="1">MERFVGSLALVWDEEWPWEKSFVGSLKKSCWKTIFGKKIIFEKCMLINNKLMVYYNGIWKDLLEFGISLGGGMVLGKAFCWISQEKLLENYIWKEDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNT6</accession>
    <name>A0AAV4PNT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_152599_1</name>
        <name evidence="2" type="ORF">CEXT_64381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004844">
        <property type="protein sequence ID" value="GIX97988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="19242" checksum="48447C1DDF1C59FB" modified="2024-11-27" version="1">MNFMYEQFISHLLFLQNLKKHIRTSLVCVLLLATFGLSVSTCGYVFLLVTNLYETLANLICVYGDKLKERSQRMPWNVETIPIDINIFKHLIFRIHEIDAAVNMYVFFLYGALISGFFNTVSVMVNDNAQFKTPSSFVYIIWVVVSAVTVLLFMSNRGSNICEKMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXN4</accession>
    <name>A0AAV4PXN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_240241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005209">
        <property type="protein sequence ID" value="GIY00641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8651" checksum="B3E0CF38DD6CF282" modified="2024-11-27" version="1">MLSPRMPRHRYLPPVITALKEAATPPKSESAHLVSRGQISLCPDQVSITGDSTPGVDLPSVCRLLVVTGRLMRSLHCSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q385</accession>
    <name>A0AAV4Q385_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_509161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005449">
        <property type="protein sequence ID" value="GIY02480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q385"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16138" checksum="78A88D5D1C011528" modified="2024-11-27" version="1">MFFRNLQFNHKLQTRVRSHESECIRNFQKRISVTLRPCSALSNEFLMEVFETTSSRVFLRPCRDDGFRYAVQKIPPMDMSSQASENVALTVEANDMRLPKTLQMMDFGMLNKKIPPMDICSQASENLALTVEVNGIRADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QH24</accession>
    <name>A0AAV4QH24_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein RER1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RER1</name>
        <name evidence="8" type="ORF">CEXT_675621</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the RER1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006369">
        <property type="protein sequence ID" value="GIY09368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QH24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004932">
        <property type="entry name" value="Rer1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743:SF0">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03248">
        <property type="entry name" value="Rer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016013">
        <property type="entry name" value="AtER_Rer1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY09368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="23224" checksum="BE24AB28311147CE" modified="2024-11-27" version="1">MENSSFEVKTDVPVVDSSPKQSIIVRVWLWISVKYQSTLDAWTPFTFSRWAATVILALLYLIRGWYIITYALGIYHLSLFLAFLSPKIDPAAHENYDEGPELPTTINEEFRPFIRRLPEFKFWYSATRAIFIAMFCTFFDAFNIPVFWPILLLYFLILFCVTMKRQIKHMVKYRYLPWTTGKAIYRGKEDTGKIVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QL91</accession>
    <name>A0AAV4QL91_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_119051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006405">
        <property type="protein sequence ID" value="GIY09599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QL91"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10765" checksum="AFF53780854C7F2D" modified="2024-11-27" version="1">MHLLNKKGIQTGNNACLCLKSSNPTLILRRKNDLLSTGCIQRLLAESAFSSSDDHPDVSCFLVYFFSSGTDLRCLIHACDMSHSRLWERSMRKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QLD7</accession>
    <name>A0AAV4QLD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_810631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006420">
        <property type="protein sequence ID" value="GIY09721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QLD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11400" checksum="B1FB9C1852E1789C" modified="2024-11-27" version="1">MLVHHRRSTLRNKAKQRLISAFHPINNDYYYLWLQIFTRKGCAKHTFPGCPSSSVYLFGLVEKASTNNVENFSFTAVVDCLASVCLGKFIPKQTPSCVVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQJ7</accession>
    <name>A0AAV4QQJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_655921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006652">
        <property type="protein sequence ID" value="GIY11485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8407" checksum="5AA4634D353A790C" modified="2024-11-27" version="1">MHLHEKIANIRRSVRKSAEMSDRPNTSVPIKSIRVNPRGKAMHTVTTQQQQPSTLNRGHAGPCTLANRGFICSIAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXG8</accession>
    <name>A0AAV4QXG8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-C2HC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007137">
        <property type="protein sequence ID" value="GIY14723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12589" checksum="B64E3AADAB9D98C7" modified="2024-11-27" version="1">MRKINTDLKTKLNCKITNQYIKLEPENEDLHITITKYLDDKQIPYYIIMPKLLRPVKIVIRGLPIDTNPDLIKSELTDMQFQVANIYQLKEGPRQNPYASLSSSTESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0W8</accession>
    <name>A0AAV4R0W8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_105561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007229">
        <property type="protein sequence ID" value="GIY15375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0W8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12723" checksum="E383D5BB0C7B0F34" modified="2024-11-27" version="1">MKSTASGSSLGYRKYLRNDLDSKIHLEISASEYLPQRETAMADSQDSILDSVLHGNLSSIPDPPSRVLKMMVISSKTVNSFYQSGNISLRMEENRDTCYANGMNDVTEATVSQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7Y9</accession>
    <name>A0AAV4R7Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_778121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007526">
        <property type="protein sequence ID" value="GIY17590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13779" checksum="930E0E5CED20930C" modified="2024-11-27" version="1">MGSDPCRLPCVGTNCFWFQCTGPQLTWNSVFLQTGYKRQSVRRILLVGEPPSFNCHRHSRRTSSKQGKLSDPHPNEEPAQLSKPEFHRTPSSHSLKNSFFVAFLVHCSGKKRARRAIPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RC66</accession>
    <name>A0AAV4RC66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_128731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007561">
        <property type="protein sequence ID" value="GIY17906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RC66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043966213" evidence="1">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9785" checksum="AE13210AB6CF2C0C" modified="2024-11-27" version="1">MWLTPSVSVVLLLHAINCEVSADNASTRTKKFLIDVGESSSNAISKPTPDHPLKVFINNTANSNTSEEETFPNFYKMDFMATYLLMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RED0</accession>
    <name>A0AAV4RED0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromodomain-helicase-DNA-binding protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CHD7_1</name>
        <name evidence="7" type="ORF">CEXT_575051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007738">
        <property type="protein sequence ID" value="GIY19321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RED0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006576">
        <property type="entry name" value="BRK_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037259">
        <property type="entry name" value="BRK_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07533">
        <property type="entry name" value="BRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160481">
        <property type="entry name" value="BRK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BRK" evidence="6">
        <location>
            <begin position="3"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY19321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="430" mass="45430" checksum="C7A6A0DE1C040FDB" modified="2024-11-27" version="1">MQITGSKAPPLKYLAEWLDKNPMFDVDPKWGPLVREKGNLPNNMAKRIVTPSEKRGRRTAASLLASAHQNLVPPVTTMSFPSTAGLNPLSFANTGMLSGFPNMKFFMDPPKSNTTSTTTSSASSTTSTNPPIFLPFGGLAGMGLTNPLFGFPGFNFPGLQGSSPLSAANLPASKDHSKDNEKSRGDKESGSSSSRKNTPASSSATPSSMTSTSSLPSSSLPFLYPPGLLYNPLSLGGFTLPPNLPASFGSFTQSGLVNGLGLNNPLFTTSSLSTTLSSAMSSATVTSPATHSILSSTPSVSKSLAHISPNKQLSSLSHLTDGQETDDESLKSLMGNHEDDDDDLDDGKMEIYDNPDKDDSDKEGFRDSIRRSPASNSTAMHIPAKNLQSDSEVLSLAKTNNENPSLELSKSRGMHDDPTSDSTDTESKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGV8</accession>
    <name>A0AAV4RGV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA repair protein XRCC3 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">XRCC3</name>
        <name evidence="2" type="ORF">CEXT_599451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007762">
        <property type="protein sequence ID" value="GIY19460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071140">
        <property type="term" value="P:resolution of mitotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090656">
        <property type="term" value="P:t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22129" checksum="4923BA0092D84B89" modified="2024-11-27" version="1">MPTSIGGLNSKVVYIHSEGDFPIKRFLQMATAFKSKNPKLQNIKLSDNLILKKVFNLGQLMHVLQKGLPELLKKVNNLKIIIIDSVAALLRCEYDSLNERTSLLLQLATEIWKLANINGMAVICVNQVSGSNKGNGKNSLDVPSLGLLWSNILTTRIKISRNSSENNEPSTRNLGLIFSSYHSHLCNNFVISEKGINVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJC7</accession>
    <name>A0AAV4RJC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_69401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007957">
        <property type="protein sequence ID" value="GIY21016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10828" checksum="0F89AA932778412D" modified="2024-11-27" version="1">MLSEVKKNQTSSGREEESIVDRCLTTSVRKKQTRFRCRGVFSVVINHLSAHRSSSVPPTFPAKKETWKELVKTSHEKNCISPDVMVPEIEGNENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPJ3</accession>
    <name>A0AAV4RPJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_294631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008328">
        <property type="protein sequence ID" value="GIY23878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12941" checksum="FD48D015CDF4E905" modified="2024-11-27" version="1">MAFPPLGLRYNKVQKYEITSLTNYLVANISGTRSLKPDTPIPPTIQLPSGTIALDTVSIPLTDKASDTMHHMWPNMAKPSLGGFWRQCHRNTNPLTIPRMHVWPRDSCHYLLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSW9</accession>
    <name>A0AAV4RSW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_13140_1</name>
        <name evidence="1" type="ORF">CEXT_681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008369">
        <property type="protein sequence ID" value="GIY24239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16668" checksum="A148023CCBBB73FB" modified="2024-11-27" version="1">MKTSGSRKGSRMMSTAGGVPAKGKNGVCDNFHCVCVCVMDDALQNIGACKRILNNLLESTQSVSKLMQQEVDKIAKAYAKETETETFKSSEIVAVYRKLFSSFVEARRNNLHLMKVELGLLQAKENASIAVESDETTETADILKNEVTLSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZC6</accession>
    <name>A0AAV4RZC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_192341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008651">
        <property type="protein sequence ID" value="GIY26251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14554" checksum="94E3493BAC61FFFC" modified="2024-11-27" version="1">MSQNRDISYSQKKTALTPIDSLSCKKKGWGVGVFRAMCSRISVTPPLPEPTNTNSAAILGVRKGGPDFRRSDRKRRDPPARCLLRSALEYPTRARTQGDGFSDPFSMVARVTKGSAAIYRRVSEIYIVCEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZM7</accession>
    <name>A0AAV4RZM7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_185061</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008699">
        <property type="protein sequence ID" value="GIY26564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000060">
        <property type="entry name" value="zinc finger protein 436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050826">
        <property type="entry name" value="Krueppel_C2H2_ZnFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24377">
        <property type="entry name" value="IP01015P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY26564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="25587" checksum="90BBD71CA5524C83" modified="2024-11-27" version="1">MSSHFASNSNESDNASTNQLSQYYETPLGIPILSVQNAQYNPMDPIPPTDAISPIHSNKCPEEFPPKDNPEPQYRSRSVARRYACKYCDKTFSYSWSLTIHIRTHTGEKSYKCTVCNKCCSSNFNLASHMRIHNRKTLHKCTKCSECFVSYSRLEGHFSTVHPGKKLNKCTQCDKCFAWPSELRRHFSCVHTEDRPYKCTKCGKCFAVAFNLKRHMRLHDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9Z2</accession>
    <name>A0AAV4S9Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_110449_1</name>
        <name evidence="1" type="ORF">CEXT_590941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009162">
        <property type="protein sequence ID" value="GIY29961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="21426" checksum="09A7EFFFE7A40F39" modified="2024-11-27" version="1">MHVRKPGSFCVYGIESRIKNKKTPRQRAKENLISCGKESSLSLDWLGSSVDVIIASVIRFRLDATVGAIAARWFGRLASLFSVEGTFYARSRPRPPSRRGWKDEDNCLPPLPPWGHLTPPAFRSLSAGTTPQHRSLQRTLTSASEGAEPLRRMVSLGSEPGSEASLSIVQENWHPVLQHTLYESIESGSQDSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SCD8</accession>
    <name>A0AAV4SCD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009284">
        <property type="protein sequence ID" value="GIY30841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SCD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11333" checksum="5455CC9BEE1670A3" modified="2024-11-27" version="1">MYSNFERNGSHEGAIKLHIFRLPSSISFVQKDSSFLSFYLSYPQIPERYFKCVSNVKKLGMASFKIPPLHMAIEQEGSVVFDPNTTVTTLPENREWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHH4</accession>
    <name>A0AAV4SHH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dedicator of cytokinesis protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dock1</name>
        <name evidence="4" type="ORF">CEXT_811331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009547">
        <property type="protein sequence ID" value="GIY32804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007520">
        <property type="term" value="P:myoblast fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11872">
        <property type="entry name" value="SH3_DOCK_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.350">
        <property type="entry name" value="Dedicator of cytokinesis N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026791">
        <property type="entry name" value="DOCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032376">
        <property type="entry name" value="DOCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042455">
        <property type="entry name" value="DOCK_N_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45653">
        <property type="entry name" value="DEDICATOR OF CYTOKINESIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45653:SF10">
        <property type="entry name" value="MYOBLAST CITY, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16172">
        <property type="entry name" value="DOCK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="3">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY32804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="264" mass="31209" checksum="C99A1BE0983DB6B6" modified="2024-11-27" version="1">MTKWSYVKDRVKYAVAVCNFKQDGPHRLHLTVGETVHILQEKEDWFYGCSTKNKSLWGIFPKTYVSVKESIVDKTGPHEAIIPREPPIVQEITSVIREWGVIWKQLYVNGELEFEVIRNMMYELIEWRRKIMSELCLWKCYFRFGSCCKWDEHGNMLNPDITSTIDLYRAHESATQRIKLMANNSVDDEDNRNQKSLSMYVHSFYVTVKNFVCRIGDDADLLMTLYDAKEGRCISENYLVKWSKEGLAKKIWNNLIIYEFYLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLF6</accession>
    <name>A0AAV4SLF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_347731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009521">
        <property type="protein sequence ID" value="GIY32523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12456" checksum="CE12C39359631851" modified="2024-11-27" version="1">MLANQVPLTKGSFFARKGWERSISSSIKSQQMSNGLWFTEIKDYTMDVLSSFWTERRANTPDFSSMCQAGEKKKWRLIGLPRLHVLRRQTNTIFLFIQIIPSQKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNQ8</accession>
    <name>A0AAV4SNQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_555621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009940">
        <property type="protein sequence ID" value="GIY35629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY35629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19203" checksum="58E86A9828B3118D" modified="2024-11-27" version="1">MQVRHEALCLKSSRSLPQQDRLRRAQHARRQGVDVEMRSSTRDHGSAFSQRAKRFLRETFKDKILGPDARRTRGPIPGSDRAQEFSPRALLREEEVAEPRAAGGGALETGRDDRRGRLHQSPAPKSGLRSDPPLPHGMEVLLEGGGGETVERNARAGSKRSRRGRAVERRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSK7</accession>
    <name>A0AAV4SSK7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_411091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009925">
        <property type="protein sequence ID" value="GIY35532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8742" checksum="24A7BBD618BB359C" modified="2024-11-27" version="1">MVPEELNQYMLQRAKSTEQRERKRQYMREWYQRAKSTVTPEQRERKRQYMREWYQRAKSNGGTKELNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7K5</accession>
    <name>A0AAV4T7K5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_153531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010741">
        <property type="protein sequence ID" value="GIY41699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY41699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="23291" checksum="6FBC731BA9AA2CB8" modified="2024-11-27" version="1">MAPSVGEPDYQTCKQVGFTQLYESVVRRVVNTEDTLQRLQERYEALLSTQKQWLLERDKLLKLIPAETARALPGASRSPTKRRAHSPEREDSSKRQRIEPPTPSPASAPAPTPAAAAPAPTPAAAAPTPTPAAPTPACCTNSYSCCTNSYSCCANSYSCCTNSYSCCQLLLLLHQLLLLLPGHQISSSCSTQASQLKPEPPRRPGRPVSVLFLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9A6</accession>
    <name>A0AAV4T9A6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein Jade-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Jade1_3</name>
        <name evidence="2" type="ORF">CEXT_684101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010705">
        <property type="protein sequence ID" value="GIY41307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9A6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20844" checksum="D43E471D292863E6" modified="2024-11-27" version="1">MSLRHNRECSLKKNSEQKQKNKRSVIIKLEHPETKPLKEANKDMVEENGDISNELIPSSPDWDPEDAQPPSLGSMEQPASTRIIIRLRKDPNRESWKNDSSSSSDVPVAFRIVSNDLDVNCENSVSEFPSIIGDDDSPSNQTCREDSESRHRYSMRERSVVSKNVKCAVEKKLVRYINKNCSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THI1</accession>
    <name>A0AAV4THI1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">sn-1-specific diacylglycerol lipase ABHD11</fullName>
            <ecNumber evidence="3">3.1.1.116</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha/beta hydrolase domain-containing protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">abhd11</name>
        <name evidence="13" type="ORF">CEXT_319371</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>1,2-didecanoylglycerol + H2O = decanoylglycerol + decanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48596"/>
            <dbReference type="ChEBI" id="CHEBI:11152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:27689"/>
            <dbReference type="ChEBI" id="CHEBI:90605"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + octadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:77107"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:25629"/>
            <dbReference type="ChEBI" id="CHEBI:77129"/>
            <dbReference type="ChEBI" id="CHEBI:186738"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + octadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:25629"/>
            <dbReference type="ChEBI" id="CHEBI:52392"/>
            <dbReference type="ChEBI" id="CHEBI:75728"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + octadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:77103"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:25629"/>
            <dbReference type="ChEBI" id="CHEBI:73990"/>
            <dbReference type="ChEBI" id="CHEBI:75468"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,3-diacyl-sn-glycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38503"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:64683"/>
            <dbReference type="ChEBI" id="CHEBI:77272"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01011285">
        <property type="protein sequence ID" value="GIY45565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="12">
        <location>
            <begin position="25"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00043667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY45565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="289" mass="32324" checksum="C4509F56E37D0E6F" modified="2024-11-27" version="1">MSKIIPVRLAYECIEVDGCDKAKSPIIFLHGMTQCKELWHDLPRTIGQATKRKIIIVDARNHGASERTDVFNFDVNVDDLLHLMDEINVQKAILVGHSMGGITSIKTSLRAPERVEKIVVEDMSVSQLTPKILKMVQQFVGLTQEVLDSIPDSVKDVDEAAKFYVEHIFKRLPPEGDNLTNTKNPESVRKFVVMQRNADGKFSVNYNNQAILKALNDPKSLMSDPSGVFEGPVCFIYGKLSPFIADGEELVIKKHFPNAKLVGIEGATHTVHVDRPKEFTEALLSFLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUG8</accession>
    <name>A0AAV4TUG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltranfer_dom domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_273998_1</name>
        <name evidence="2" type="ORF">CEXT_243421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011634">
        <property type="protein sequence ID" value="GIY47838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="293" mass="33483" checksum="77B5F0986B830E4D" modified="2024-11-27" version="1">MANFEADVDKSSENFMKANRPEGQIIYIANRIQQVLMISWEDITQLLFMSADDLGWGRLTNKDIMDIGCGDGSRSTKAIIDVFPTVRRVIAMDSESEKIRGAFGNTCPSKVFYMRADILHSSTFKGYEGSMHAIFSDFCFNDFDDHETAFRNVYDLLTPGGSAAIRFPLKIPIYDWIKEVYAKWMPGVTPWAPRTQVENLPEHYYRQMFTRLGFTIRRCETCDMHFKIGSYANLKRSLAGCEEWSSVIRPELLFPFNEDAYARSLKYCSVSSAGMCSMKAETLLAFLIKPNDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3M4</accession>
    <name>A0AAV4U3M4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_665491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012236">
        <property type="protein sequence ID" value="GIY52401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13094" checksum="752B4AF99C413D0C" modified="2024-11-27" version="1">MAIVFPYCLTANLEQTFSQRSHLGNFPLFNLQVQRKSLSGQQLSFNLDTQEGRNRNEGQHRTFLQLLPSPPHPDSLPRCAGGRSGWRKGCKNGVLECKTVGGLDVFAKYRIDNLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8F7</accession>
    <name>A0AAV4U8F7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_293221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012466">
        <property type="protein sequence ID" value="GIY54068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8F7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10084" checksum="8BD962F9B90EA28E" modified="2024-11-27" version="1">MEGYSSFVFFSLSSLSEGFEFIVSVWNIMCEAVLRFCHQDEDSPLHSTQDSTRRNPDSAVPFPFFEADAKFGDKRWYSHTSLKMMQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDF3</accession>
    <name>A0AAV4UDF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ventricular zone-expressed PH domain-containing protein homolog 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VEPH1</name>
        <name evidence="3" type="ORF">CEXT_748641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012671">
        <property type="protein sequence ID" value="GIY55760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010314">
        <property type="term" value="F:phosphatidylinositol-5-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039888">
        <property type="entry name" value="Melted-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21630:SF10">
        <property type="entry name" value="VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21630">
        <property type="entry name" value="VEPH-A/MELTED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY55760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16195" checksum="0C97C00F25F11B42" modified="2024-11-27" version="1">MHELFAQVLTNRDLSRAGDLFSIEDKNLVSDISDVLIKIEEIASASDFTQNDNNQSVVEICITRVTSAIRDTGTIEQHAPAMVSLLESCLNHDLRPLPKDEDPPHAKIASDIVSCIFFGNRPVLLSPPLPLGLHTIFFQNHCLKCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJZ0</accession>
    <name>A0AAV4UJZ0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">palmitoyl-protein hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Lypla2</name>
        <name evidence="4" type="ORF">CEXT_235541</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01013012">
        <property type="protein sequence ID" value="GIY58089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF68">
        <property type="entry name" value="PALMITOYL-PROTEIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY58089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="21733" checksum="31D3119EDC7E2720" modified="2024-11-27" version="1">MVLVILDTVGLLDCKYSSFHMSSFCPTAPTISVTLNGGVKMPSWFDLKSMSADGPEDEQGIKRASETVFQMIEEEEKRGIPSSRIVLGGFSQGGALALYSALLCPKPLAGVIALSCWLPLYKQFPYAAVGIAHDLPLLQCHGELDVVVPFKWGRMTYDLLRTFMSHVELKTYKVLCHTTNDEEMKEVGRFLEKVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULW4</accession>
    <name>A0AAV4ULW4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methionine adenosyltransferase 2 subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Methionine adenosyltransferase II beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MAT2B</name>
        <name evidence="9" type="ORF">CEXT_410381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. Can bind NADP (in vitro).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013125">
        <property type="protein sequence ID" value="GIY58927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000357">
        <property type="entry name" value="Methionine adenosyltransferase 2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="RmlD-like substrate binding" evidence="8">
        <location>
            <begin position="37"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY58927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="329" mass="37041" checksum="ED74D44EE5C363DB" modified="2024-11-27" version="1">MIVTPALLNRFNLDSNPFCNIYDRWKSKSLLPAILVMNVLITGASGLLGRAVGAEFKKHSWKVLGLAYSRIKDDLVKVDLNDFEAVSKIIYQFKPHVIIHCAAERSVDKVTEDYENSKKLNVDVSKHLAKLAGDIKAIFVFISTDYVFSGESPPYKEDDQPSPLNLYGDTKLEAEKRIAEINPDSMILRIPVLYGDEEYIGESAISSLIKLLLKKVPTKVSNYEIRYPSNTVDIASIIFQLVMKKLQDHSLKGIFHWCGMESFTKYEMIKVIAEVHGISYDHLSPDNNPSPGSKRPKNSQLSCKRLQDIGLGMHTSFTDGVKCFGKFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPW6</accession>
    <name>A0AAV4UPW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lysophosphatidylcholine acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LPCAT</name>
        <name evidence="11" type="ORF">CEXT_580071</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013245">
        <property type="protein sequence ID" value="GIY59837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042171">
        <property type="term" value="F:lysophosphatidic acid acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF52">
        <property type="entry name" value="LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="10">
        <location>
            <begin position="128"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY59837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="230" mass="26265" checksum="B7EDB6B99FE40E86" modified="2024-11-27" version="1">MTKLRGKTKKMTAEKLKSTVSEDIINPFVLNQELSWHQFLKAIIMTFTILPLRFLLMIMILAIAWLISVVTLLGISKEQAQGLDPLTGWRRRWCKPLIVSIVRFVFVVGGWFWIPQKGRRATAKEAPILLVMPHSSFLDTVLVIALGCPSMVVKDSTERTPFFGDLVKYTQPLFVVSEDPNSRRRIAEDIKRRVTSGKDFEQLLLFPEGGCGNRKALLQFKLGELENRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URK8</accession>
    <name>A0AAV4URK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_491871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013334">
        <property type="protein sequence ID" value="GIY60516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13345" checksum="832E805404BE1DB1" modified="2024-11-27" version="1">MRGVHLFESAKLWTSGHYGQPDIYFSAIVGARKSNGIGPDVARHTQSGELLSVFVTHAKIDPERTDTNPSKNSFWLEGTCPFVDVCRIGVCIRLIRSFSSVSDFGPRVLTARGKSIRQIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UU56</accession>
    <name>A0AAV4UU56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_295971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013470">
        <property type="protein sequence ID" value="GIY61451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UU56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17564" checksum="62AC35DB2164F6B9" modified="2024-11-27" version="1">MIEYPSRMYNPYFKLLFLTVKQIYFHDCKKAQKQAFLQKNIVFHMCQLRPVIMTRGREPGAPSAFALDNHSILSRLINGSNDLPLSHWVLHLTSIELENTASIQGRPLRPKKTVPSGLTPFILSRLDLSAPRFSMCAAVDFFNLNTCSVSNQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVL8</accession>
    <name>A0AAV4UVL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_433351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013556">
        <property type="protein sequence ID" value="GIY61956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13712" checksum="0D4EBDA2B76D3F5C" modified="2024-11-27" version="1">MSELFHESRLVRLEFCRTQKLLVSSACSLEWMSPSLVYFLLGRICLKESSVTESCRRGESGFNQCIALVTRCSSNAIVPFFRSGFSDFVWIRMKRTIRISPTGWRCNFVSSRGMGFCWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY27</accession>
    <name>A0AAV4UY27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_74191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013597">
        <property type="protein sequence ID" value="GIY62235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7971" checksum="A9BD80BB60A9BE88" modified="2024-11-27" version="1">MGIKSGKKSTKLQIALEKGMIPSRACRLQRRRGSAKQHFEGRKSLPIDYDGKNKDQPFQRIFESDLPLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V522</accession>
    <name>A0AAV4V522_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TBC1 domain family member 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Tbc1d15_1</name>
        <name evidence="1" type="ORF">CEXT_309221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013981">
        <property type="protein sequence ID" value="GIY65312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V522"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13732" checksum="111AE27A1533B3FD" modified="2024-11-27" version="1">MKKSHGPIIEWHPLRLKADDCQTNSPELETSDWEDVSTSVGYKANHDESLDAVEIKAVRMPNTERFDIADLKSYKRTDSSDEHKTVITFLLKDGTNIPSFQFKTSDFGRFCAALDNYINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V722</accession>
    <name>A0AAV4V722_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_123000_1</name>
        <name evidence="1" type="ORF">CEXT_161511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014074">
        <property type="protein sequence ID" value="GIY66096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V722"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="261" mass="29692" checksum="9B5452214DDA5152" modified="2024-11-27" version="1">MNAASFELRCWAHTGTKQSETQNVLGLKWDTETDELYCVSPETDMGISDNISKRKLLCIVNSIYDPIGFTSPATLLPKLLLQEAWRNKLDWDEEILYGNFKKATLHIFTDASAHGYACCSFLRCEDEGEVKVSLISAKARVTPVQKPTIPRLERLGAGIGARIASTILEALDLPLKTYFWTDSMIVLGWITNTEPWNTFVGNRVKEIRELTKVEDWRFVPGDVNPADLPSRSCNWFELLQSKWWRAQNGSTNLQNFDLTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHV6</accession>
    <name>A0AAV4VHV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_172581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014611">
        <property type="protein sequence ID" value="GIY69937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17124" checksum="93074EDFDFFFBCF1" modified="2024-11-27" version="1">MFFTLWPKKAQQIAHATFNTTPSYINLLKEKKNTSYLRLAIRLMFIIFKERLADDVDSKSSNAKKSNHTTSSLQQHRKERQMLTLLHMDKLEFRVELILQNETHTLIEILVLSEKIRVACLVVEVPRNIVKFSPFTVEPRKGNKLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKM4</accession>
    <name>A0AAV4VKM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_701811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014690">
        <property type="protein sequence ID" value="GIY70573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20031" checksum="F1FACFD98476C4B9" modified="2024-11-27" version="1" fragment="single">GTTDAAFKAEADELENLQNSYFHTFQGIFGEERSCLISRIPMGRITNLNWEHGRFVWLPRIEKAFPASSASRAGLQKSEAGVAQNPFAVSPVWFPAACGRHHGAKLKLHHKGSCLFLHLYFVHCRVEQTNFSNEGPNRTNTADTADAHQPLVICFLQKPMNLDDGYGVACAVRNILASGSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VT34</accession>
    <name>A0AAV4VT34_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulatory factor X-associated protein RFXANK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_438321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015079">
        <property type="protein sequence ID" value="GIY73422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VT34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.290.30">
        <property type="entry name" value="Regulatory factor X-associated C-terminal binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038308">
        <property type="entry name" value="RFXAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029316">
        <property type="entry name" value="RFXAP_RFXANK-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15289">
        <property type="entry name" value="RFXA_RFXANK_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Regulatory factor X-associated protein RFXANK-binding" evidence="2">
        <location>
            <begin position="59"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY73422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="12872" checksum="CFC65568E92A7B78" modified="2024-11-27" version="1">MSKSKSTKKKSSTSSIVDLNSEFVNESLPQSSASSEISVSANTEKDYVSKVSSTKSEGSSNDSCACSSSMRDVSTDIGADYMNNSILEEILNEKKAALLQSPEIVKLLRGQQLKIQNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZV2</accession>
    <name>A0AAV4VZV2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">for</name>
        <name evidence="19" type="ORF">CEXT_811151</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01015375">
        <property type="protein sequence ID" value="GIY75683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd05572">
        <property type="entry name" value="STKc_cGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000035">
        <property type="entry name" value="cGMP-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000064">
        <property type="entry name" value="cGMP-dependent protein kinase, isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002374">
        <property type="entry name" value="cGMP_dep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035014">
        <property type="entry name" value="STKc_cGK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF111">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000559">
        <property type="entry name" value="cGMP-dep_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00104">
        <property type="entry name" value="CGMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0140">cGMP</keyword>
    <keyword evidence="9" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="17">
        <location>
            <begin position="40"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="17">
        <location>
            <begin position="158"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="297"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="18">
        <location>
            <begin position="533"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="303"/>
            <end position="311"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="GIY75683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="584" mass="66838" checksum="19D8A8C7375ECD78" modified="2024-11-27" version="1">MASVLTILGERCPVEAEVIAILRSLLSKELIQKAILDNDFMKNLETIQIKEITDCMCPVEYAKDSLIIKEGDYGSVVYVMEEGRVEVSKEGKYLCDLGPGKVFGELAILYNCTRTATVKAIMDCKLWAIERQCFQTIMMRTGLVRQAEYTNFLKSVPTFRNLSEDVLIKIADVLEEAAYNEGDYIVRQGARGDTFFIISKGKVKVTMRSPESGEEKFIRYLQRGDFFGEKALIGEDVRTANIIADEADGVMCLVIDRDYFNRLISNINEIKEKNYDEIHPVKRRIDEDLLKLKLSDLRVVTTLGVGGFGRVELVQVANDPTKSFALKIMKKAQIVETRQQQHIMSEKNIMEEVDSDFIVKLYRTFKDKKYLYMLMESCLGGELWTILRDRGNFDDNTTRFYTACVIEAFSYLHARNIIYRDLKPENMILDTQGYVKLVDFGFAKKLQNGRKTWTFCGTPEYVAPEIILNRGHDISADYWSLGVLMYELLTGTPPFTGPDPMKTYNIILKGIDAIEIGYQKGGIQELQKHKWFDGFYYDGLRTRTLVPPIIPQVRSPVDYSNFDRYPPDADPPPPDDLSGWDQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2R3</accession>
    <name>A0AAV4W2R3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoprotein TPR/MLP1-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_504701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015477">
        <property type="protein sequence ID" value="GIY76355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012929">
        <property type="entry name" value="Nucleoprot-TPR/MLP1-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07926">
        <property type="entry name" value="TPR_MLP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoprotein TPR/MLP1-2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14977" checksum="2051A8886433CAAD" modified="2024-11-27" version="1">MNDNLNITAVLHQKCSLKIQILTEQAKAADQTVADSRESWTRQEETFNSEMEALKSKTADLEKHNEELHHQLEIMGTQMAALQSTKWEETPYSSIQSDLKDTQHLLSVIQFLKKIKKLIPTNLMHFSLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9Z5</accession>
    <name>A0AAV4W9Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_160981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015890">
        <property type="protein sequence ID" value="GIY79457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11200" checksum="90312239EF4A8BE0" modified="2024-11-27" version="1">MFTVQVPEISTYISRNVSKILRDIKLTIFSDNSMGSSIQFKDKQTRSASGVHVCLKTTTSHKNMGIMSIKLQCLDLRFNVHSSGTRKFNLVSQRCVKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WB10</accession>
    <name>A0AAV4WB10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_179681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015950">
        <property type="protein sequence ID" value="GIY79977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WB10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="16610" checksum="AAD1CB42E7BD18C5" modified="2024-11-27" version="1">MFSGNEGRSMCFAGSPGIPKGERNIMSTVTAINTQLPLGGMNASVHFELDCNCLRHSPFIKPFKMEIYPLLPSLEMIPHNYTGVKSDLKSGRFGKKSFGRTYHLSDISLRSDLKSGRFGEEVFVAGRSSIRMIAPVCAPFEEKTQRSPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFA1</accession>
    <name>A0AAV4WFA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_477951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016034">
        <property type="protein sequence ID" value="GIY80656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043820100" evidence="2">
        <location>
            <begin position="17"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY80656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17852" checksum="7ACF46A161540B54" modified="2024-11-27" version="1">MIATVLALVIEKIVLGNTVCYRMWELTDVLSDYLHYWHQQQCNTSKKSKRSKTQKRPRTSDADGFIPVPRHLTAQPSTVLEAEKPMETENQFAVLETVTDPVIIPAQMQMKTRPPSFLRPTQSRMAKNIPRADNFDSKTKHIPLQRPIPQTDCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHC9</accession>
    <name>A0AAV4WHC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vegetative incompatibility protein HET-E-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HET-E1_3</name>
        <name evidence="4" type="ORF">CEXT_56691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016126">
        <property type="protein sequence ID" value="GIY81455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="170"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="208"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY81455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="510" mass="55366" checksum="62D09659C224B81A" modified="2024-11-27" version="1">MSGLEMSINFQPKRHLRFAWSEWELLIQNASKELNGKGAYGCSRDRIVKVWQLNSGELHASLKGHSASVTCVAFSPNGLFAVSGSEDATLKVWGLTLGLIVSTFQEHQSKVMAVAVTCDSRRVLSVDSQGQHRLWQADTGTQLVVCTKPSHNVAVHANMVFAVGGKNDCSDAITCYTVTYDCQTIVTGSNDMSLKVWEVGSGKLTQVLVGHESMVTCAACAPLSPSLVVSGSADCNLIVWDLTTGNDNFTLRGHTETVTHVKLTLDGTLAISASDDNSLGIWSTSTGLRVGLLGIHQTILNIAGALNLSQVVLQLANQNVVPLLKLHNNPTKGMMLDLPPGTPVTEEAKTPGHSWRGVVPQRVFLRGNLKREQSFDSFYWDMRNTSIWRALSGTAVWGSRFHPSDLQSKAKLPKHKMLKKQQSMFACFPEFMTQQVSPQQLLSPQGLIKELDQPLRKTGLPEFGRITPKLTAQKSLSRAASLEETGASANSNQEGANLVTIKQSAVCTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHN9</accession>
    <name>A0AAV4WHN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Mfsd6_0</name>
        <name evidence="8" type="ORF">CEXT_467711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016158">
        <property type="protein sequence ID" value="GIY81714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF37">
        <property type="entry name" value="RE36877P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="288"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY81714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="479" mass="53436" checksum="E823D5542419A47D" modified="2024-11-27" version="1">MVLKPLFGAIADYFDNLKALMVVFMMVIMLSSSLTLSIPRKENMISSDIKCAATGTTLYFKSKPSQECMVDVLVSKPLKCYMYCEECTEFQPQSNSSDKACIKKKMHPVELTVNLEEQNGSTHFFNVKNMTLADRKMNTLCFVNVTFACSSYCEPVLQECFTGKQQPEYNSDQFWLFLIFGTMTISLSGVCSSFSDAICFNELGENGHLYGKQRLWGTIGWGLLSPVAGYINDLVTGDSFLKAYQPGAILLLSLIFLDGRAVCRLKTKNLKCSQNVCKDISIFIKQFKVLAFLLSVLMVGSFTALLWSFLYWHLLNLGATKIILGVVPAVQCFLGELVFFFFSGKLISKFGHFNILILNFFVFGVRFIAYSYLTHPWLVLPIELLQGPTYGLFYATMASFAHSAAFLPGTEVTVQGLVGSGFELGMVAGNLIGGMSMQMYDGAFTFFWAGVVSFGYCLVHTVFTIIVKVLEKEHKDSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIL5</accession>
    <name>A0AAV4WIL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_611061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016151">
        <property type="protein sequence ID" value="GIY81649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17040" checksum="814B3E337DDAAA85" modified="2024-11-27" version="1">MSYLVKRKILRFVKNVILVNFCDPGLRFGELELDVAKATRSFAPYRDKFWSMFQDHWKTTCESEAEVLLFGFTQCLMMSPHGTDIEFLMVCAFLTEFVSYSFLKKKCYSAAPHFRVSALCYRQVFLPSRQGTLSGSAESVRDHKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WV91</accession>
    <name>A0AAV4WV91_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TonB C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_722931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016792">
        <property type="protein sequence ID" value="GIY86417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WV91"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10310" checksum="558585D8A77A1A02" modified="2024-11-27" version="1">MPFHRIFHPYPSPFRPTGYVTVTINYRGESEQIKLNKLNAVFRSAEFIRSAITVAGTLKMARIYHPREKPKRLQIRTIIITTIEPSSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2X6</accession>
    <name>A0AAV4X2X6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017215">
        <property type="protein sequence ID" value="GIY89497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2X6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="21269" checksum="0AD4E8166FDC5A72" modified="2024-11-27" version="1">MNPSFHNDMFPQPLLSTISKFTKLFLNEHYFLRDNFIKLSFVPAPNHYFYANANDFLKEGWLWRSSTSENYRVSLPLWRELPLYLAYGRRDKVHPIKHDRTIHNDNSLCTIFFVTECPTSPCRITLASTILDAPELPLRDGRWLFHVPVITVLLQETEGPLLLWRIQSPILSLVKRGVEGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XA89</accession>
    <name>A0AAV4XA89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ homolog subfamily C member 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DNAJC17</name>
        <name evidence="8" type="ORF">CEXT_320471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017427">
        <property type="protein sequence ID" value="GIY91532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XA89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY91532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9667" checksum="F0287CC7B7E30927" modified="2024-11-27" version="1">MRIRKRLYPDKKAYRKKALTCHPDKNPDNPKAAELFQQLSRALEVLTDKAARAAYDKVLNARKAAKIRHRELDGKRKKLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBH3</accession>
    <name>A0AAV4XBH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017538">
        <property type="protein sequence ID" value="GIY92455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7874" checksum="7187FA655D998B8C" modified="2024-11-27" version="1">MTGEVPLEKNRLMALKIVWWAEQDSSSKGFRFLGLLQSLQQRGRNATGCLQKLRFSISGFFENVLLAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFE2</accession>
    <name>A0AAV4XFE2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="22">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="primary">ATP8A1</name>
        <name evidence="27" type="ORF">CEXT_612671</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="27 28" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17 22">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 21">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 22">Membrane</location>
            <topology evidence="2 22">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 22">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="22"/>
    <dbReference type="EMBL" id="BPLR01017725">
        <property type="protein sequence ID" value="GIY93951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000021">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 20 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 21 22" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 20 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 22" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 22" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="845"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="869"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="901"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="942"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="970"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="1010"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="25">
        <location>
            <begin position="41"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="24">
        <location>
            <begin position="128"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="26">
        <location>
            <begin position="806"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="19">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="583"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="665"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="753"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="759"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="779"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="782"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="783"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="783"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00051303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="GIY93951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1131" mass="127258" checksum="C71B756157BE3C9F" modified="2024-11-27" version="1">MKPGIYGDLGELGDDDDDQTSGITEIPDIIEHRVIHLNALQKQKFCINRISTAKYNLFSFLPKFLFEQFRRYSNIFFLFIALLQQIPNVSPTGRYTTAVPLIFILSISAIKEIAEDIKRHLADDSVNKAEVLGLRNGLWTQIRWTDVVVGDILKITSGHFFPADLVLLSSSEPHAMCYIETANLDGETNLKIRQGLPQTSNWLTPKDLGRLRGTLECEAPNRHLYEFTGNLRIAGKQTLPLGADQLLLRGAKLRNTNWVFGIVVYTGHETKLMMNSTTAPLKRSTVDRITNNQILMLFLLLIILCLISAIASELWMKNHSTNDWYLGIDDLSSSNFGYTFLTFIILYNNLIPISLQVTLELVRYVQAIFINMDINMYDKNTDTPAMARTSNLNEELGQVKYIFSDKTGTLTENIMVFKQCSIAGIKYGSPDIDFDGSNLLSNYLNNHNTAVYIKEFLTLMAVCHTVVPEKEQDSGDLNYQAASPDEGALVKGAKQLGFVFTTRTPHSVIVKAFDREETYAVLNVLEFTSDRKRMSVIVRCPDGKIKLYCKGADTVIYERLSDRQQHKDITLEHLKEFASNGLRTLCLAVAEIPQDFYEQWCETFHKASTAIQYRERKMQEAAQLIEANLILLGATAIEDKLQEGVPEAISDLLKADIKFWILTGDKQETAINIGYSCKLLSPSMALMVINENSLDNTREAIRRHMQDFGDLLRKEHDVALIIDGKTLKYALSSDVRRDFVDITLSCKSVICCRVSPIQKAEIVEMVHLATNVVTLAIGDGANDVAMIQAAHVGIGISGVEGLQATCASDYSIAQFRYLTRLLFVHGAWSHARLCKLILYSFHKNICLYVIELWFAIVSGWSGQTLFERWTIGLYNVIFTAAPPLAIGLFDRTCSAETMLKFPAMCFWVWIIDSIIHSGALFWLTYLSVDNDIVWANGRDGGYLVFGNMVYTFVVVTVCLKAGLEMNAWTWLTHLAIWGSIASWFIFLWGYSNCWPTLPIAADMVGMDNMLLSSAVFWMGLIIIPFIALVGDFTFKVIRRTAFKSLAEAVRESEITNTDPAKVIVLATKQRLTETARLLKNVFRRPSSHVSAVPLEMELQHGFAFSQEEHGAVPQSELIRAYDTTKTKPQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFX3</accession>
    <name>A0AAV4XFX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_531631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000316">
        <property type="protein sequence ID" value="GIY93851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF200">
        <property type="entry name" value="ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF B, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY93851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13058" checksum="E045D875E33E7748" modified="2024-11-27" version="1">MWCQMGRCTEIGERPEAIDGEWGQWEPWSPCSRTCGAGVSLSQRHCDNPYASWRWKILYWRKKALQNVQHSGEREEVAKSSYVASRGFAHNVGAKCDFNVDGSLGPHMQGNVVSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJR4</accession>
    <name>A0AAV4XJR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SOCS box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_191284_1</name>
        <name evidence="2" type="ORF">CEXT_643171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017734">
        <property type="protein sequence ID" value="GIY94023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03587">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.750.20">
        <property type="entry name" value="SOCS box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001496">
        <property type="entry name" value="SOCS_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036036">
        <property type="entry name" value="SOCS_box-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07525">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00969">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158235">
        <property type="entry name" value="SOCS box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50225">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SOCS box" evidence="1">
        <location>
            <begin position="331"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="403" mass="47402" checksum="A4A52EB77590E055" modified="2024-11-27" version="1">MKSNPCISKNYSPITRLVCARDVVRLDFVLAKTVSYLNLNLGDFSMDKEYSSFICTEEGIRKHFDGTRELMYRFNLDKATGLDSNLNIKTRTNVNGFCPSKNFSHALYLRAEDFFYKILIQLVVTAKNKQKLMRWFLNLKKNDIHLLFGDTLESDTLMVELSLFSDKLKTDVFLAEISKNGGKIQEILSIRHDLISRSVHSKLFDFIPIFLKYQSEWTYTSGDYKSMKNLFRRGCYSLKFMQRLMLRKRPRGMSKRRHFLLLLTLACFNSKRQLYREAAPGLQQMWRSLPDPFLSYHEMHKTLQRTLEHTELRSLYVFYKKVVGIETFALKPRSLQDLCRVTIRRTLDKNNLCLPDAIEKLPIVPSVKRFLKLSDMQCTTTSTETMLQKKRRPSRVHLAYFCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQZ4</accession>
    <name>A0AAV4XQZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_503991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000701">
        <property type="protein sequence ID" value="GIY96788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15522" checksum="573D32A639940750" modified="2024-11-27" version="1">MGRMGAFKEQKEKLICFRKYRSFPQEWIQNLTNSENIPYNTSFLLNSPAFSAYHLKLMNSNRQFNPDEHPSTIKRRQSKLIKLPHSTQQTIFAKSPAFCRTPRLMSSRSTNNYLCTRHPEMPLCVYSQWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVZ8</accession>
    <name>A0AAV4XVZ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_792711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018263">
        <property type="protein sequence ID" value="GIY98144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10713" checksum="10E7E83AED793B5C" modified="2024-11-27" version="1">MKEIFLSLWNVFISPNNKKQQRNLSPLILRANLSQSWEINCCSRIETGESDIWRNIFSPVSHPAFTFRSQNYSGQDTNREDSPIRRNIVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWT5</accession>
    <name>A0AAV4XWT5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cystinosin homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CG17119</name>
        <name evidence="14" type="ORF">CEXT_423071</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cystine(out) + H(+)(out) = L-cystine(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:66172"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:35491"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:66173"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cystinosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001058">
        <property type="protein sequence ID" value="GIY99536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015184">
        <property type="term" value="F:L-cystine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000016">
        <property type="entry name" value="Cystinosin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000018">
        <property type="entry name" value="Cystinosin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005282">
        <property type="entry name" value="LC_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00951">
        <property type="entry name" value="2A43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131:SF5">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0769">Symport</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043495480" description="Cystinosin homolog" evidence="13">
        <location>
            <begin position="22"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY99536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="375" mass="42408" checksum="4EF350A208E2DCA0" modified="2024-11-27" version="1">MYPVTVLLVTIVSCFICTSSAANLLQVSVQDLSLEINENKTFTVYTSEPVSEDIKVYFNYSEDSNIYPLPDDLVIQKGTKGKIVYTVRAHKAGHTTILAHTTPAIVKTNNAFVRVGVYKVYNWIVVSSVIGWLYFICWSISFYPQVIENYRRKSVVGLNFDFLGLNLTGFIAYSVFNIGVRYIREVQLEYHIAHPTGVIPVEVNDVVFSVHAVFVTILTIGQCFIYERGNQTIAKSTVAVLALVWSTAAVFLLLTALHVNKYTPWLTFLYFFSYVKLGVTLTKYIPQVVYNYKRKSTVGWSIGTVLLDFIGGLFSIGQMFIISYNFDDWYSLIGNFTKFGLGIASIAFDVIFMVQHFCLYRHKSSSVEYAQESLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYY6</accession>
    <name>A0AAV4XYY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_5775_1</name>
        <name evidence="3" type="ORF">CEXT_174551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001106">
        <property type="protein sequence ID" value="GIZ00038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ00038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="516" mass="56915" checksum="ACEE9A0EE35A3E2B" modified="2024-11-27" version="1" fragment="single">NLSQSEMPQQRTQKEHKSSRRPGSRWHSFHFSGKVILCSVIFGFLLILIGGILLAIGLDRDEETKSDDYDDLQKKPPLVFVGPVIMGIGGFTVIVGILMCLIETKVFRKRTGDANPLINSERDESAANNSENIGSNPAAMPSTSGHRDKHRHGNRKKSPSPRINRKKGSKSPSPKLDLSSSSQSSAPMSVNSSKNYLSASDTFLTPPSSLSQEHLPMQGNSRDAENQTSSSLLKSFTSSGKSWTTSNEFQTPSASFIDDRPFFQRSPDSDEMTTPLPFSNALGLSAIEKAKREFLTPKNSTDVLESSSEEEVAPEENKQIIREETKQISPEENKHEFLTPKNSDAEILDPSSSDLKRLEARMKSSGSNLPHTTVEKGLSDKTGAENIVNEKPHDLLKQELPKMDNILEDNKSSPSGHPEDVEHSDVQVDVLLDAIEDEVKGNTDSHKNNSEVVNEPHHDIEIDNTAVDSCETEQKSDEPPSPQISENIPYADDISDDICNQEEQNDLDLNIDDADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ05</accession>
    <name>A0AAV4XZ05_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Exoc4</name>
        <name evidence="2" type="ORF">CEXT_157181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018459">
        <property type="protein sequence ID" value="GIY99778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032584">
        <property type="term" value="C:growth cone membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="439" mass="50486" checksum="D669F72DAF27B9DF" modified="2024-11-27" version="1">MYDNLQDTEIKLKNGSSDRSLRKLVLVCKPALKNITYIFDVLKNFATEIESDSDIEPGSHCPLHTFIFDCANNFLDQVNSEINRILENASLNLESWSVSTISDATSEREGSEKQILTSTLILNDNLKELQKLLSNLPDYSNHFLQLIYYVILDYKDLVHKIFKTLFDEEHYILSICWAKDRDIRRLLKSFFPTGSFCKLPNLGEMIESPEEIRLRNKEESELLIRNLHSEEHASWEIIKDNTILLILPYGPPETASQDIPEGTAELHALNAATGLKKLAKEYEDFSDVCLLALHLEVRAHCFNYLLSFDEDDASKAWETSIRSLTDDLMKMDETLVSVLTPKEMKYIFEGLGELISSILIHSVSQMTQMNEILVKRMHRGIFTVQCCLSNITMTREVSMERARQYIQLLNSTCDEVLNEIVEVGPIFKNMNMPQFSDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y241</accession>
    <name>A0AAV4Y241_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_261811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018518">
        <property type="protein sequence ID" value="GIZ00220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y241"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7557" checksum="29B9A5DF7780F98B" modified="2024-11-27" version="1">MALWKTRVDTSRVDVLYIVIGHESGNDIDTEIMSVFFAKHLTAGGLMGCETPTDPPPPYNEGKSCVTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5F9</accession>
    <name>A0AAV4Y5F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_437141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018637">
        <property type="protein sequence ID" value="GIZ01206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17750" checksum="F0A6F9A315A43A81" modified="2024-11-27" version="1">MNLTKHCFQVPINYRPHRKQFYKKAILLRNIGPSIRKEENSTQKHKKKQLRLNPDLMITNTMDQPSARPCKLLPLSLAGPDPWGFKISCLRFPISRRNTRRNRKNLFFIFWQSDTFGKRIVLFGIGFPSIGGLRTLEIGRRIYHGMLVRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6P5</accession>
    <name>A0AAV4Y6P5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_801981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001354">
        <property type="protein sequence ID" value="GIZ01824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6P5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11987" checksum="CFE6B9D351181ABF" modified="2024-11-27" version="1">MGKSVGAKSLSVQCQWRPTFPETGPLLHRMLFQPPTGRMECNHLAKRFLFHPSTPSLHKCISFSCHGNETLRINFSSEVRGGEKVHLIRRGIFSMPIFGFGGFLLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8S6</accession>
    <name>A0AAV4Y8S6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_71161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001600">
        <property type="protein sequence ID" value="GIZ03420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8S6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.10">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00104">
        <property type="entry name" value="tRNA_TsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818:SF0">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="4">
        <location>
            <begin position="65"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="4"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ03420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="363" mass="41215" checksum="61506D3F9F31F981" modified="2024-11-27" version="1">MSDFKKLASDILLARRELKNIRQECMKQKASLKSEVALIQELLKNTTECNRTCSCKKNDDKNYSMSPIGFISSCFKNKNGIPRQPSLCPAAKGTLSIEKKIFNNPEHSFIGLDGFSYIWVLFVFHKNGSENAVKAKVHPPRLNGSSVGVFSTRSPHRPCAIGLSLIKLEKLKVRNTLFLSGIDLLDGTPVLDIKPYIPFYDIPPVFKENPTLEFIKSKSIQTTIQQDNDLSTEEINDITPSVVVSSESKISIKSLDCNVASYLTKTPQYLDVLFTNRALKDLENFHIRESHKGYCDNCFNFTSHSEAKQTIVDVLKNDPRSVYRRNKCSDRLYYFHVSDLHVTCWFDENIAEVLQLKSIKNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9N7</accession>
    <name>A0AAV4Y9N7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gem-associated protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Gemin5</name>
        <name evidence="6" type="ORF">CEXT_147851</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001517">
        <property type="protein sequence ID" value="GIZ02874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9N7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056424">
        <property type="entry name" value="Beta-prop_GEMI5_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052640">
        <property type="entry name" value="Gemin-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362:SF1">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23775">
        <property type="entry name" value="Beta-prop_RIG_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Gem-associated protein 5 second beta-propeller" evidence="5">
        <location>
            <begin position="110"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="329"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIZ02874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="491" mass="55504" checksum="B29F771AF3EEFD1A" modified="2024-11-27" version="1">MLVSASLDLSLRVWKIDENKPLKGEVGEVIFSEEGKPNFTSYSKTVSAIRGLQGFLTYSKGTDENRNSLLFCFDLNKLLIWNVVEKKCIMQLPFVSGIVKQLVNSTTNPNLCAICPGDGIVRILNTQTETNLDMGFIFVNYKAKILCASWHPILENILAFGTSEGRIGVIDTFKRKLLFYFETVHAESEDNGKYFLYSCGGGIVYLSDFNRPNESSLNISELLNQPSNLEKTDSSTVCWKNDYSCIFFGTFKGFTDVYNVNFDFLIRYEIDVKTVESIVFHPESTYVSPEGSPLRFWLACQGNSENIYICDTSKIFEKENVIRGPFKKLSGHKKNVTSICWSQHIDGQLVSGSKDGSMIIWNVSAGTIIASYTPNREMVCTVQWSTFDQDVIYSAGYDSCVRTWKISEHLGAESLNTAPRKYPKFEANVKVSEEASLTQLKTNPGDLENSSRTDVNDNQVSESKNEDILDTSTINCHKEYMREWKEKKSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YA00</accession>
    <name>A0AAV4YA00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_377231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018886">
        <property type="protein sequence ID" value="GIZ02994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YA00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12063" checksum="C295B1AEA64AD6F2" modified="2024-11-27" version="1">MMEKINSRGWGVKKSTLLSSSKSFFEDVSLHAPSNPFRDIFSTLSGIDDVTRGSARWPLQSRQRHFYDGQTYPMEEFLLLPPVIIFLAGLPFWRKGRSFFYLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAG2</accession>
    <name>A0AAV4MAG2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">amdhd2</name>
        <name evidence="10" type="ORF">CEXT_545061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate</text>
            <dbReference type="Rhea" id="RHEA:22936"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="3.5.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01002007">
        <property type="protein sequence ID" value="GIX68883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106279">
        <property type="term" value="P:negative regulation of UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000023">
        <property type="entry name" value="N-acetylglucosamine-6-phosphate deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="58"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX68883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="31442" checksum="E2FB33C4D3491D01" modified="2024-11-27" version="1">MSSRGKLIQFTNCKILRDSKIIREDLWVRNSKIINPEPVFYDEKITSDLKVDCGNALIVPGFIDLQINGGFGFDFSTPKDDIASSINVVAKGILQYGVTSFCPTLITSTPDKYHEIIPKIKIQNGGKHGAGVLGIHVEGPFINKEKCGAHPTQYIKTLKNGIEDIVETYGNLYNIRILTLAPELDTNGTVIKELVRQGITVSLGHSACNLSDGEEAVVQGATFITHLFNAMLPFHHRDPGLVGLLTSEKIPVNMKIFYGIIADGIHTHPAALRIAYHSNPDGILNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCU3</accession>
    <name>A0AAV4MCU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_560611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019648">
        <property type="protein sequence ID" value="GIX70105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16439" checksum="9C7ED27D10D6F081" modified="2024-11-27" version="1">MAAIVKGNRGDYYRDGIIHDRLPNRQGRLLAFAFCCCNLLPQRNFRSGGGGGGLERGNRGDYYRDGIIHDRLPNRQGRLLAFAFCCCNLLPQRNFRSEGGGGEGKGPVIKFEMTPFHQKQANIFLLVCRNGIVSITQHPMFQGCSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MG41</accession>
    <name>A0AAV4MG41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PGBD4</name>
        <name evidence="2" type="ORF">CEXT_88461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019688">
        <property type="protein sequence ID" value="GIX70602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MG41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="506" mass="59321" checksum="70C25C771956D575" modified="2024-11-27" version="1">MEQFPFIKSECLLQPITGDNPIDYFRHLFTENMLDEVIAQTNNYAREVLCRRETKQHSRINAWKETTKEEILIFVGLILHMGIIRINRIEDYWKTDALFGLSVFSYNMSRNRFNVLLRALNFSKIPEQDAEPSKDQLYKIRSMVNLFNTRLAEIYYPGREISLDESMILLRGRLMFKQYIPDRCQKYAIKLYMITTPDGMVIKFMVHSGMVDDSGGKGHAQKVVLNLLEGMLDVGHSVYMDNYYNSYELAKCLADRKTHCTGTIEKNSNTFPKEVIEKKLKKGETVAMYANGVMIGKWKDKRDIIYISNEYKNDIVEKTYKRGERKSKPLPVIQYNKYMTGIDKQDQMLAYYPCERKTIRWPTKIFVHILQLMISNSHFLYNKYSTENMSLYDFRLSVIRCLLKPQPVLCVPKHNSPELEHVLKPRDEKRNGKILRKQCKRCYSQGKRKDTIYICKVCDDSPGYCLDCAKDYKICVQHALKDFQFLALSRPTDSSKKLFNALDDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHC0</accession>
    <name>A0AAV4MHC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_492731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019796">
        <property type="protein sequence ID" value="GIX71857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13805" checksum="A5BE3F0992683DF3" modified="2024-11-27" version="1">MFNYVITLLEGCNPESVSPRPIDRHFRSPSLDCSCLSGQFRFSTLFRTTDVRPQIHHPEDASGFFVLGGNLRGKLKVAVSEKRKEKKKKKKQSVFLGIERPQHLHPGIEAEVENNRCAHSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPI4</accession>
    <name>A0AAV4MPI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_537871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002492">
        <property type="protein sequence ID" value="GIX74278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="27997" checksum="5C08A21BC9DA0CA4" modified="2024-11-27" version="1">MIFIKTCVRAFEAYCSRIACIPFSSSETGERVIPGSAISPALKEMCFGKRLFWRLRDGLMVLSPTHQNCLAFCAVNNRKEQLQVLGQWGEGFLLIEIQVRFRAGGLNNPLTLCSRMHRSNEIKSCSHGRLGKDNGEHLKEFIYPSTNPFPSKLTQEIPAKATFAETRHVAFKQTGWSWNKAKTKLLLFRVLYLLVRRHSARLCLAQPFYSSFKLIPSLIQAAKRCGPDYLFGGGEHPSVPAACAKLLCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRF4</accession>
    <name>A0AAV4MRF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_310651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002463">
        <property type="protein sequence ID" value="GIX74006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="18042" checksum="F74450A712B4C3C8" modified="2024-11-27" version="1">MRLKDGGKAIQNSIAKRIKAIIIGTPRRCLKLSYQNLKGLAEVMPEEKKCPYISMKSEDKNNVLRIDNGFNPTHGNLLGSSHGVLVKMVDLPPLLISTVADKPRETQVEKGTLRQNRTAEEICQLFIRIKFPQRFYPKCSEKIFWEICRRTCLEMIPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWE5</accession>
    <name>A0AAV4MWE5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Flavin-containing monooxygenase</fullName>
            <ecNumber evidence="18">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">FMO5</name>
        <name evidence="19" type="ORF">CEXT_317742</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:24468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16269"/>
            <dbReference type="ChEBI" id="CHEBI:17735"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:24469"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>hypotaurine + NADH + O2 + H(+) = taurine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:74111"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57853"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:507393"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:74112"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>hypotaurine + NADPH + O2 + H(+) = taurine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:69819"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57853"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:507393"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:69820"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>trimethylamine + NADPH + O2 = trimethylamine N-oxide + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:31979"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15724"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58389"/>
            <dbReference type="EC" id="1.14.13.148"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:31980"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="18"/>
    <dbReference type="EMBL" id="BPLR01002695">
        <property type="protein sequence ID" value="GIX76810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034899">
        <property type="term" value="F:trimethylamine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000159">
        <property type="entry name" value="Dimethylaniline monooxygenase [N-oxide-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 18" id="KW-0274">FAD</keyword>
    <keyword evidence="4 18" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 18 19" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="10 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="GIX76810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="410" mass="46722" checksum="78275A0EE07013FA" modified="2024-11-27" version="1">MASPKKKVAVIGGGFCGIVALAQLKEEGGFELVCFEKTDKPGGTWCYREESMEAVASIMPTTIINHSKEIGALSDFPPPKEFNNYMRHYELYQYIAEYAKSKDVLKYIQYNSEVMEVRRAKDYKETGRWIVTVKNTIYNEVSTDVYDGVCLSVGHINRPKMPHYPGQDLFKGDIIHTHTLKGVEKYREKNVVVVGMGCSGLDAAVETSHVYLSDTRSHVIRRLGPHGYPFDYLLARRWIFLLMDILPYEWTSYLLENVYLDPQFNRDLYAVKPDHHALSKDPVINDHIHSKFSSGSIIQKTDIESFTENGVIFKGDTEVTEADVVIMATGYTWKFPFLEEGIIVKEGDKINLYKLMFPPHLEHATLAVLGFVLPFGPGFPIGELQCRWAAQVLARKCKLPSEKRNGRRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY22</accession>
    <name>A0AAV4MY22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_383221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020304">
        <property type="protein sequence ID" value="GIX77183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9613" checksum="9D084EA769AF0C0B" modified="2024-11-27" version="1">MRPSVVMEKHYPIQELASAPALDGLFEPQQSVTVLLSGMASLDVYASRLINLTPPGYVAPCKTLLSVYLFSSCDTFVKHAPLLRDVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYJ8</accession>
    <name>A0AAV4MYJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_694941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020342">
        <property type="protein sequence ID" value="GIX77612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11047" checksum="920B1CB14B765531" modified="2024-11-27" version="1">MIRQSHNIKNQLKTINESFPEIKITLSGELLKIYSKDSGEHRKITQFLKNYKMDFFLLTPRNERSLKAVVKELPRTTLSTEIEQELSAHKFTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZQ7</accession>
    <name>A0AAV4MZQ7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SCAP N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_302741</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002809">
        <property type="protein sequence ID" value="GIX77994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032936">
        <property type="term" value="C:SREBP-SCAP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045540">
        <property type="term" value="P:regulation of cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030225">
        <property type="entry name" value="SCAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057041">
        <property type="entry name" value="SCAP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46378:SF1">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24006">
        <property type="entry name" value="SCAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="SCAP N-terminal" evidence="6">
        <location>
            <begin position="97"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX77994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17259" checksum="2D1333E03256F8F5" modified="2024-11-27" version="1">MDSTPRTRPYAPDIHDKIARVYYSHGLFCSSHPYSVIFVTLCIFMLCCYPLLYLPLLGSSSQEFITPVQGFVPPDIVLDGVEGYKFNGPRWFQGPPINELLRNHQIYQRTANHTSLGDLCLQVSEPLDELASDILPHYDCLIIFTKQHLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0K5</accession>
    <name>A0AAV4N0K5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_379991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002832">
        <property type="protein sequence ID" value="GIX78295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10546" checksum="D5364065748790E3" modified="2024-11-27" version="1">MMEDLFSLAVSFSKGGWSLLVSTAPSSCKKNIIICEVSKIPITTQPGLEVPWTVNLEHNKRDAILVVEFSILNFFSWLHNFNDRDFDFCRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3B8</accession>
    <name>A0AAV4N3B8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_713951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020477">
        <property type="protein sequence ID" value="GIX79224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3B8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13767" checksum="1B350DE47DC699DD" modified="2024-11-27" version="1">MFPHARTRWALSTTCQRYKKKICATSKGVNERKSAAFLSASTFPPCQRSLAKQSSALHASQAWTDPVPEQFTLIRIVWMSSSATRYVHWWTEADLWRASFSPLVFLLLCKLYTMSFGTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8U3</accession>
    <name>A0AAV4N8U3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_16118</name>
        <name evidence="3" type="ORF">CEXT_552911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003108">
        <property type="protein sequence ID" value="GIX81250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8U3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:DNA transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002492">
        <property type="entry name" value="Transposase_Tc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01498">
        <property type="entry name" value="HTH_Tnp_Tc3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase Tc1-like" evidence="2">
        <location>
            <begin position="69"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX81250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="21100" checksum="3BA72E0DC6B0A835" modified="2024-11-27" version="1">MPRSSKPSDFEKGIIIGRHKCGRSLRDISSDLKYPKSTVAYVIKKWKVSGDCRNVPRVGRPTKLGDRDRRVLTREIRKNRTPPMALIREEFQQASGSVVSMNTIRKEAHLHGFHGRATAHKPLITKSNRAARLMWCKAHRNWTVDQWKRILWSVQILIGSLYEHSISRYTYIPRASIHMTPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCE4</accession>
    <name>A0AAV4NCE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SUMO-conjugating enzyme UBC9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UBE2I</name>
        <name evidence="11" type="ORF">CEXT_294781</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003239">
        <property type="protein sequence ID" value="GIX82450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000013">
        <property type="entry name" value="SUMO-conjugating enzyme UBC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="4"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="8">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX82450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="20051" checksum="79706C15F4B6DA5E" modified="2024-11-27" version="1">MSGIAIARLAEERKAWRKDHPFGFVARPTKNQDGSLNLMNWECAIPGKKSTAWEGGLYNLRMIFKDDYPSTPPKSLFIKKSFKIFVSDFQGKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAITIKQILLGIQDLLNEPNIKDPAQAEAYTIYCQNRLEYEKRVRAQAKSMAPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDS3</accession>
    <name>A0AAV4NDS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cathepsin L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_497421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003243">
        <property type="protein sequence ID" value="GIX82504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000006">
        <property type="entry name" value="Cathepsin S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="7">
        <location>
            <begin position="69"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX82504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="278" mass="30200" checksum="2A64A1C4CFF7CA1B" modified="2024-11-27" version="1">MNIGDISRILLRNPTLRLRSTKTSLVGGSRGFHRTPQPQGGHGTPFFQKGSQQVFRSDPRGVHGNAEWLQSRTGHCGQDQQSCGSCWAFSTTGSLEGQYKKKTGKLVSLSEQNLIDCVTVNNGCHGGTMDDAFEFIKNENGVDTEESYPYEAVQDSCSFKPQNVGATCTGHVDVPTGDEEALKQAVATVGPVSVAIDAHHESFHDYKTGIFDEPSCGNELSDLTHAVLVVGYGSEEGADYWLVKNSWGESFGHRGYIKMSRNKNNQCGIATMASYPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHY1</accession>
    <name>A0AAV4NHY1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_733431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020869">
        <property type="protein sequence ID" value="GIX83463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHY1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24694" checksum="8DE3E9D5C68E41E4" modified="2024-11-27" version="1">MPPRVRKRNDSVSLEGILRHLTMRKIVWGHLINPPPPPTPRERKRRKEKRINKKGACALTEDKWILSIDIGAGPNSAKRTKVSLGRTKYSGDLFTRTNIEWKGRTTKKKKKSFDLTELGVVGAIQNVKTIIYYHPGRSHTFHPHSAFGTYLPSVAFGGFTFFPFEIFGRIIEAYRFIVPIGRVFYPQCRLIWPLVEFLSVPKLRSSTYQAATNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNW3</accession>
    <name>A0AAV4NNW3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GBETA1</name>
        <name evidence="7" type="ORF">CEXT_39151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">G proteins are composed of 3 units, alpha, beta and gamma.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021064">
        <property type="protein sequence ID" value="GIX85460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000007">
        <property type="entry name" value="Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="7"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="178"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="269"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX85460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="33115" checksum="9F3628FC0AFB8750" modified="2024-11-27" version="1">MRTRRTLRGHLAKIYAMHWGSDSRYLVSASQDGKLIVWDAYTTNKVHAIPLRSSWVMTCAYAPSGSYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIVTSSGDMTCALWDIETGQQCTSFTGHTGDVMSLSLSPNMRTFVSGACDASAKLWDIRDGMCKQTFPGHESDINAVTFFPNGYAFATGSDDATCRLFDIRADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDSMKAERCKMHPTSVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NY46</accession>
    <name>A0AAV4NY46_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_2721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003790">
        <property type="protein sequence ID" value="GIX88668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NY46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15462" checksum="D5024A5BFDC0BBAC" modified="2024-11-27" version="1">MGILKFAAVAHFCIAVQKSFLQCTKGIFSRGCFGVKPMFHVKRKKHEICFIHTDENILGGGPLRVRAHQSNFPPLFLEGCATLFLSIPTLNAPVEVSARTCVVTMLSVCSSISSCGFGRKSGRVWDVWGKQSKGMSLRGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NY50</accession>
    <name>A0AAV4NY50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rap guanine nucleotide exchange factor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RAPGEF4</name>
        <name evidence="5" type="ORF">CEXT_479622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003881">
        <property type="protein sequence ID" value="GIX89683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NY50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd04437">
        <property type="entry name" value="DEP_Epac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="DEP" evidence="3">
        <location>
            <begin position="148"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="290"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="4">
        <location>
            <begin position="428"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX89683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="466" mass="53063" checksum="832CFAE214CB97CC" modified="2024-11-27" version="1">MWRCLDYLNLILQYKVLMEVDTVTLCTLGIGTAFGESILDNSPHSATVVTNEHCELLRIEQKDFKAIWERNRHLMEDIVSPISTLRTLTGLPLQEDCRTSNGNVRSFSPLGKKDSLTPDGLNPALPITQEPSTALSRAGWVLRTLILCQSSHLIRDRKFHARTFRKCLVGSEMVDWLMHQGAIYVRIHSRSQAVGMWQALMEEGVISHVTNEHQFKDKFLFYRFREDQQEVTSPTSDDKHQAEKELPDVLGDLLRLAPDAVFRMILRKPSNERTDEDLEIIYEELLPIKALSHLSSSVKRELAGVLVFESHPKAGTVLFNQGDEGKSWFIILKGSVNVVIYGKGVVCSLHENDDFGKLALVNDAPRAATIITRENNCHFLRVDKDDFNNIIRDVEANTVRLKEHGQDVLLLQKIPTDGRAVDGTHSHYKYMVMAGTPQKMLEHLLETRIDQRNDDTTDTFLEDFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P025</accession>
    <name>A0AAV4P025_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_176131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003828">
        <property type="protein sequence ID" value="GIX89126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P025"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="21034" checksum="7381237862C554E3" modified="2024-11-27" version="1">MHSRGPFVQIHLQLSLLLKGEANLIYKQVKNNISETCDNPLKPQRDFNNELTSHRRVTIPPLSDDGERGPFVQIHLQLSLLLKEEANLIYKQVKNNISEICDNLLKPQRDFNNEPPSRRRVTMPLLSDAGERDPFVQIHLESCLLLKGEANLIYKEVKNNISETCDNPLKPQIDFNKEKVADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6Z5</accession>
    <name>A0AAV4P6Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide exchange factor DBS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Mcf2l</name>
        <name evidence="7" type="ORF">CEXT_605721</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004164">
        <property type="protein sequence ID" value="GIX92814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051336">
        <property type="entry name" value="RhoGEF_Guanine_NuclExch_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056466">
        <property type="entry name" value="Spectrin_DBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22826:SF211">
        <property type="entry name" value="LD43457P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22826">
        <property type="entry name" value="RHO GUANINE EXCHANGE FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23289">
        <property type="entry name" value="Spectrin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="6">
        <location>
            <begin position="12"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="DH" evidence="5">
        <location>
            <begin position="552"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00049987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX92814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="641" mass="72905" checksum="031D34FA4FBDDB14" modified="2024-11-27" version="1">MEENSCSLCVQDVAHLLQNKYAVITGGKTLDGFPIITFPDSTVEFLNLSEDEFKKLMLFLTSVPSMQDADRGFVLIIDRRNDKWSSVKTILLKIAGFFPALIQLVFVLRPAGFLQKAISGVSNKFFKEEFKFKVIVCTSVEELHTHIDISQLTNDLGGTIAYDLNDWIQQRTRIKAVERFSANTKEISITLQDLIVQLQASVLPNDVPTTMAFIEEHTKEHHELKDDIQSAIRHGETLLSCIRRPSVEDASLDLCPDKLVNVAAVERLLIQLEETEKNFDSFWDEHMKKLQQCLELRHFEQDFKEVQSVLSSCLDKISDMPISGDSVSKVREALKDADLNRAVEVQEQGQKLIENNHYAIDSISPKCVELEKMVGDLKQQLQRKLDMLRKYCDLHEKLKRQIFGISAELENHSILDGTISPETRALVQQVLKRLEDMQTVCEKRKSSLEKLAAKPVRPIQAVVPEPKVPSHPPLRRPSPDGEKKILRKGTKATIEICFEENEAEVASYFQPIQTLSNNSSPRNSADILRLKENLEGCSSTPEQECQRNLGHKLPLGAYLLKPVQRITKYQLLLQDLLKFCEESITELKEALDTMLTVLKYVNDSMHQVAITGFHFYSPKNMAEKKVQVMHLKMLSKLPKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAV2</accession>
    <name>A0AAV4PAV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_749681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004113">
        <property type="protein sequence ID" value="GIX92277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11296" checksum="CDE392966997A9E1" modified="2024-11-27" version="1">MYRKKIMISNIKKYSQKSITRNKRRTELFQIKKGITKSRDKSQCFDAFDKQNKIGAQEIDCLSSAFFKRLFDADVSQNAEADVCEKRLTSPNNYKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGJ1</accession>
    <name>A0AAV4PGJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_574501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004625">
        <property type="protein sequence ID" value="GIX96280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22908" checksum="70AD2428C3ABD409" modified="2024-11-27" version="1">MVSKRPIVVDSIFELCCKEKDEEYTCHELEVNHLIVENEDLDFDRIKSLRLLEIIGINSGSSLTIPRRCSKSAPHDLPLQFRDEALPLQSRDDALQIPRRGSSQIDLPQFRDSLFPPRRDSSQFRDDNPATMLTSAPHDLPLQSRDDLPLQSRDEALPYNPRDEPLPLQSRDEAQRQMIVPYNPATRLLPQSRDDAQSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PK62</accession>
    <name>A0AAV4PK62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_705261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004774">
        <property type="protein sequence ID" value="GIX97390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PK62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8690" checksum="CCA421C7F799EEA1" modified="2024-11-27" version="1">MPNSRGTERQKATLTQPHLTMTHPSLTGSSGSLCTNHGERKEKFLSARIGYCSFRLLCGIYEPRIAFTIMIIYGLDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PP20</accession>
    <name>A0AAV4PP20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_662381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004954">
        <property type="protein sequence ID" value="GIX98710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PP20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10934" checksum="51643479C7C0A3C1" modified="2024-11-27" version="1">MVQRVVRDFSAKLHPPSAAAVLFFLRGFRECFAECEKIFQISGWRFPKTLRRNTRSAPFFVSPLFCGKEQELVVRRFVPVLNVIYSHLSLSVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUD1</accession>
    <name>A0AAV4PUD1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat domain-containing protein 54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ANKRD54</name>
        <name evidence="2" type="ORF">CEXT_197861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005043">
        <property type="protein sequence ID" value="GIX99404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13508" checksum="8C489954906F3A86" modified="2024-11-27" version="1">MTESDSGVDTGSESNESNSMSVGSPSRSDEDKDVNDFVEKAHPTYPHLVMPFGNLQPAACSYGFSDYRQQEQIRKIKPGLRRKNAVRWKQQAILNVDEVIGERKLRSAANCNAIETGKNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PY41</accession>
    <name>A0AAV4PY41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_761211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005456">
        <property type="protein sequence ID" value="GIY02558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PY41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20203" checksum="BD339CA6331FB0D2" modified="2024-11-27" version="1">MSHGIVYVKEVDCITLPLTEIEFLNELNSWIILFLSSVLTSWENRIKKQEKFFCTISVECLLTLKNASSTYARNRICCVPKVEKKFPFSPKKVPIAYLVKYYIHPHGSVLTIPGGRISISRISQNLFRTILLTSVDLADLHSPFRIFHLGGYLLRVRLWSGRFVALFRASGSYFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PYC1</accession>
    <name>A0AAV4PYC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_695761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005403">
        <property type="protein sequence ID" value="GIY02047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PYC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10015" checksum="DCCA07EA851146CA" modified="2024-11-27" version="1">MIPCLSHHWTVKRRLKIPFNPFPLRCTAHSEDHPVQKSSDEDNDDLYCCPARRENDFKTPLSPNPFLFCSVMFDLGSFHRENHPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8A9</accession>
    <name>A0AAV4Q8A9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Short-chain dehydrogenase/reductase 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Retinal short-chain dehydrogenase/reductase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SDR16C6</name>
        <name evidence="15" type="ORF">CEXT_113471</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005762">
        <property type="protein sequence ID" value="GIY04844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8A9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052650">
        <property type="term" value="F:all-trans-retinol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000131">
        <property type="entry name" value="Short-chain dehydrogenase/reductase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="14">
        <location>
            <begin position="95"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY04844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="356" mass="39653" checksum="FB97A7000414436B" modified="2024-11-27" version="1">MQITSTRREVGIFFLQGEKKEELVSDILVEAFRQCGTSSSLSCHTGFVQPAESINMSAWEIIFEFLVVLVKTFGVIGLALFRWVIPEPFKSVREKVILVTGSAGGLGRQIAQKFALLGAKVVLVDIDETRNNETLQNIKQMQAKAFAYTCDVSNENQVEELADKVYREVGDVDILINNAGVLPGRPLLELTNAQIKKTLNINTLAHMWMIRQFLPRMLDRGEGHIVAISSIAGILGCPYLVDYCASKHAVIGIMSALQEELSEIGREEQIQLTVICPSTMNTGLVQYPKTRFPSLLPILDVDKASDIVVTSILRNKRLVVIPTVVHVIYKFVNLFPPQVPLLLQRFLGYTIDPNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9M7</accession>
    <name>A0AAV4Q9M7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_284731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005917">
        <property type="protein sequence ID" value="GIY06022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13103" checksum="1D77AE67387F1DCD" modified="2024-11-27" version="1">MRVDHSRSQYTLLVHEASLEDEAEFQCQVPPLCSLLEGMQILIVPPFSKSLTDVLNKLPSSNEMGCFFDLKGKLDLLIRPPARKIPLSKKGLEESILLLGDKVFPACKLFSLSGKCLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QG84</accession>
    <name>A0AAV4QG84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_603081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005950">
        <property type="protein sequence ID" value="GIY06363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QG84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="22348" checksum="CE796934C6074002" modified="2024-11-27" version="1">MSLTTKLLLVFITVLNTRWILYMIAYPLVLPPVSMAAAHGGKWWNPCRFLLLPLAPALTSTLGLISLSAFVLASLVMWFRKYRMRFLLRSSIFIVTSISLVHFVCYQISNTSHEVCVLAYITSDRLWLPYSAVIYITLLVIARYYCCKPVNITKVLTVRFQPAEFMIYWLLLLVNTRHGLMINEPVKPASNTINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIN0</accession>
    <name>A0AAV4QIN0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_451231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006339">
        <property type="protein sequence ID" value="GIY09184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9361" checksum="F9EC91676CF79A3E" modified="2024-11-27" version="1">MASSSTCQAIIGFLERRGSEQTRCELNFPAAPTTGQRRKLRNLSLQCLIQTPWRVMHANRAFLDSSDLDRSVHPNPCIKVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJE6</accession>
    <name>A0AAV4QJE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_793831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006123">
        <property type="protein sequence ID" value="GIY07548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043484087" evidence="1">
        <location>
            <begin position="31"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20540" checksum="95C5988943C41BEC" modified="2024-11-27" version="1">MFCRLQSGDKLTMIAVLWLSIILVTSSALADQNNDELLFSTRNTDNQRSSKLLDAVQAIQRRQVRLTPPPNTAANRIPRAPAVSPQQLAAAFPSRSRRPQIAHLPNQRREPFAETNQHEIQQFTEQRPQIEEVQQPTKRKNGASYRFCDTFGCDCTPPAKAKCCKGYRYDRKNNKCRELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QK52</accession>
    <name>A0AAV4QK52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_535931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006274">
        <property type="protein sequence ID" value="GIY08649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QK52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7603" checksum="070B9036FC5C4FD1" modified="2024-11-27" version="1">MEAAENSLLNPQMTPVKCSPKHIYSPEPLRKKAPGIYINYTLSDLRPGKGVQPRAARYSRRRAINGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QM97</accession>
    <name>A0AAV4QM97_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_399361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006615">
        <property type="protein sequence ID" value="GIY11168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QM97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="16769" checksum="0568C632BBC867ED" modified="2024-11-27" version="1">MISRLIRKSSNQLGLSKCLLRIFIEHILRLSFGFHSILSPKIHSQTELFRYVLSYLLLPKIVQRPYIYPEYLCNPTEDSKNGYFLSQSFRVLLRDNDINSNNILDICLFCEPSSCHEEINVICFSAQICASFPLKDHTGRHGTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNN9</accession>
    <name>A0AAV4QNN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Antizyme inhibitor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">azin2</name>
        <name evidence="9" type="ORF">CEXT_423391</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006335">
        <property type="protein sequence ID" value="GIY09153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00622">
        <property type="entry name" value="PLPDE_III_ODC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000005">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="8">
        <location>
            <begin position="86"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY09153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="475" mass="53970" checksum="CF15675E3BD30922" modified="2024-11-27" version="1">MIHSWKTYFNSIEKIFSLSTPDNLSIEKMNHQNGHIDAERNDAQKDFYQILAERTKGEIYESSFDFISKATQEMQERRSFNTFDLADVLMKVQMWKQKMPYIRPFYAVKTNSDPVLLKLLVLLGFSFDCASEGEIRFVLEAGGDPKNIIFAHVIKPPGALLYAASVGVDLMTFDSKEELLKINKLYPQSRLLLRLSPQDVKCSFDLSDKFGCDVKEAEDVLTFAKNLNLNVIGISFHVGGLCQNSHSYAATIRASRDVFELGKQLGFEFTILDIGGGFTGSKGSEKLFNEISQVIKSNLKEYFSETDIEIIAEPGTFFACSAVSLTTAICGKKERNIQYNGTNPIRRFYYLNDSIYGSFFHGVEQYGFVLKPLLNELELRQRPVYSSTLWGQTCCGEDLLLKEHMLPDMEEGECIVWENMGAYCRVICSTFCGVPLPAAKYIFINNPRLNMEWLNNSSDVVDFLSRTCSLVEKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQX7</accession>
    <name>A0AAV4QQX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_20771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006737">
        <property type="protein sequence ID" value="GIY12088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13139" checksum="769898D152EAAF02" modified="2024-11-27" version="1">MPEHRSDTPINRTNNLQNQMTYLYTCHLAWPSAPMELPSLNTSSSFLLTNDVERVENSFDPSFENVGGGERALANKSRCHPPYLLTVSAKFAEENFDFNAKIRHGANWQQNHRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSV6</accession>
    <name>A0AAV4QSV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_454921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006616">
        <property type="protein sequence ID" value="GIY11180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11058" checksum="0277409544E8B6D4" modified="2024-11-27" version="1">MGFEQGHTSWQHPLLGHCQKGQRLKAIVTWATAMKIFSLFFQIISTMIHENEIVPLKNSLSFILPSPPVGVLLLVHTNWTRPTEIKPTSSKNVVIKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT01</accession>
    <name>A0AAV4QT01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_813201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006783">
        <property type="protein sequence ID" value="GIY12394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043472794" evidence="1">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13540" checksum="6B561D336494A645" modified="2024-11-27" version="1">MSNRFLLVSVLDSLICIHYTDFEEHLENAESVTILLDKDEKKGVNSRCYSCVRLNSSGICMATKNAANKGKKIIKLAHGRRNRRKARVENLNKRYGHGQWLRPQRFLEELVRWTGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QW05</accession>
    <name>A0AAV4QW05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_459571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006799">
        <property type="protein sequence ID" value="GIY12501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QW05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10634" checksum="770B6D5214029255" modified="2024-11-27" version="1">MPFSPLILSPLFTGLLRDILNPLHQQNIPPRIKGTLMRNGVFRTLIAQNSRGDFQEFHPPTSSFFPGKGALRNCKTRPIDYRLGGCLLWPKGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZ48</accession>
    <name>A0AAV4QZ48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_171611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006918">
        <property type="protein sequence ID" value="GIY13332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZ48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY13332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12249" checksum="451AD630A04EC14E" modified="2024-11-27" version="1">MRLDNIHNCSGRDGKIDLRSLTGGKGEQKIRTPPNECQMSGASTDIHLIQNQSMFGMLCFFISPSVASILLFLKRKIPRVRFFTDFQLFSSCKSSPLGRIFFGGGVLSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2I1</accession>
    <name>A0AAV4R2I1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_2791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007098">
        <property type="protein sequence ID" value="GIY14525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2I1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10195" checksum="E44CFE79369F9DFF" modified="2024-11-27" version="1">METFEEEPFKPGTVADLLLGRSHFNEIDWLQLGSWLQLGDCFVASFSPRLFPVVLLHFTMDERYVKNDLDKSWVLEGFFCVWLSFVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAV9</accession>
    <name>A0AAV4RAV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_586581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007679">
        <property type="protein sequence ID" value="GIY18840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14624" checksum="7D568E889A628581" modified="2024-11-27" version="1">MIKPSNRGTAPTTNCGVVVDYKTFSTSTISPLTNQVKNLNRGRRYMACQRGPRARKGPCLIFPSSTVSEAKGYQVDNKFDRRWAIIVNQKEGFLISILPRIHGFILFILKRASLLVVVDVTGELIWQIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RB66</accession>
    <name>A0AAV4RB66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_757981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007699">
        <property type="protein sequence ID" value="GIY18945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RB66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="13492" checksum="A481680486DDFC51" modified="2024-11-27" version="1">MSQNCGTLIGIVDSSGVLFMNMIGTFGIIVFIHNIIVLGFQYCDTLVGLMDSGGILLMDIIGIIALDHSIVVVGLSIVKQYSTKSHYCDTLIDLMDSSGILLIGLMDSSGILLIGLMDSSGILLIGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RG03</accession>
    <name>A0AAV4RG03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_740221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007877">
        <property type="protein sequence ID" value="GIY20410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RG03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11200" checksum="C688E428CBD249AB" modified="2024-11-27" version="1">MLLKKVKEMKANPSLNRLSFSPRNCTLNDKDAIKHHLSTPFRNVAPILLEPRHPSWNSFQMKAFMRALCLTAMFNLIWCPITGQTIWEYSHFQALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RI47</accession>
    <name>A0AAV4RI47_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Melanin-concentrating hormone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_65154_1</name>
        <name evidence="2" type="ORF">CEXT_494471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008033">
        <property type="protein sequence ID" value="GIY21568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RI47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831362" description="Melanin-concentrating hormone" evidence="1">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16942" checksum="20B46FF8ED69048A" modified="2024-11-27" version="1">MALKTSYSAFFCEIFLLNLSTSVLSQQIPPENRVVLSPLALGGMLQGLLNMQVRPDTGFYEEKYKTIFNDDNVKHEPPKYESVLHLSDEELDKLVASYNTKEVLSNDEKILKSAVSGQSSNLCFDVDKITKNRLLGLMCVLKKRKELPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLL9</accession>
    <name>A0AAV4RLL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_250281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008023">
        <property type="protein sequence ID" value="GIY21474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12395" checksum="DE8DF09593761A9E" modified="2024-11-27" version="1">MALIYKVQVFAGGNHGTYCTAPILYHSNFNRTLNRMTFDGLHLSPLLVRRNSVDKFHKSMLLLYNGTDISLRNLQGEAQSNCTAPIWYHRKSHFVPSQFGPNTQKNGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTQ6</accession>
    <name>A0AAV4RTQ6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell growth-regulating nucleolar protein-like winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_471711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008253">
        <property type="protein sequence ID" value="GIY23253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058719">
        <property type="entry name" value="WHD_LYAR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25879">
        <property type="entry name" value="WHD_LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cell growth-regulating nucleolar protein-like winged helix" evidence="3">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY23253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9780" checksum="880A2ABEF07977F5" modified="2024-11-27" version="1">MDSSPSNIENQEKSIKFNWCAACEEILQNFPTGLREKTLRKKVIEKYRTFDGNSNTISDSKLKTIIREELSKNSNFFLYIDPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXZ5</accession>
    <name>A0AAV4RXZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibronectin type-III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_54342_1</name>
        <name evidence="2" type="ORF">CEXT_91591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008473">
        <property type="protein sequence ID" value="GIY24987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="29"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14911" checksum="0430BECAF8B8B1A3" modified="2024-11-27" version="1">MIRNSHANAQPAAAVAGNNSVILGWPLKTGRNFRRLSGSTGLPNRLTRWSLEYKGNLPIKRYHLQMKNYSTGGADWLDMDDKIPSNATSYTVRYLAPAVTYGFQLAAVNEAGHSNWEAKNLTMPADGKFQRFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S322</accession>
    <name>A0AAV4S322_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_597181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008684">
        <property type="protein sequence ID" value="GIY26448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S322"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12757" checksum="A1675FB33AC50027" modified="2024-11-27" version="1">MWNVILDGNASATKKHEETEDPQYNKRLETPNQAKPTPSISYYGSHKYQYAREEGHVCEDNQGNPVTHVGRVECPASPDVCSVLVMLRTNLHRSQLTQLNCKEIPHYLFSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFJ3</accession>
    <name>A0AAV4SFJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1758 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_239050_1</name>
        <name evidence="1" type="ORF">CEXT_416021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009251">
        <property type="protein sequence ID" value="GIY30603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="436" mass="49504" checksum="E4009CC251E7B5E5" modified="2024-11-27" version="1">MPSVQTISPHNFMSRYSSKKCESVAGTKGSTTVQATMSTPSCMREVLLMTLMVEVVSGNMRKRVRCLLDCGSQRSYILRSTAEALHLKSLSSEKLTHSLFGGARTESKNHKRYSMRLRPVGRSTGYQFDFLDQDIICGVIPRIPKGPLMKELKGHRIWISDMGDDYPEIELLIGSDIYGQILTGEVIQLNEGLTAINTKLGWTLCGEPKELNVQSLEGAQSMLITNLHVQNMKVSDMWDLERIGITDEVQTFSTAVEDQLVQEQFLKGLSRYEDGRYCIGISREDQHYLKFLWWENNKIVEFRHKRVVFGVTSSPYLLAAVISFHLKNVHAKFEVVAEKLLHAFYVDNCVTSVDTNVELEVFIQQATAIMADAKMELRMWTFGPEQELSLQNVEPISPVLGLKWDRIEDSLFIPFKSEPISNLSKKKTTIDSTFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJ57</accession>
    <name>A0AAV4SJ57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Metabotropic glutamate receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mGluR_1</name>
        <name evidence="9" type="ORF">CEXT_249071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009556">
        <property type="protein sequence ID" value="GIY32861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJ57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044011251" evidence="7">
        <location>
            <begin position="24"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Receptor ligand binding region" evidence="8">
        <location>
            <begin position="85"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY32861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17366" checksum="B93380551852F143" modified="2024-11-27" version="1">MAPSAARCLNLRLFFCLFVPSGGIKVAWQHRDPLQPADEERVHGRGEHPAGDGLRGGAAAAVRERLGARLLLRPQEPPRRRVRGRPGICPRMDPIDGALLLGHLKNVSFRGLSGDEFHFSENGDGPARYNIIHFKQISGELQMDTSGRIQRWRTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQG1</accession>
    <name>A0AAV4SQG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_486561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010020">
        <property type="protein sequence ID" value="GIY36214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8011" checksum="A7A573842709EADE" modified="2024-11-27" version="1">MDMKDTPRFEAVSCGPQSTFQGFIIPLLYMEGMEMIKNPSGAGIKDPKTRWYGYPGRGEIPYTIDKSLGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZT6</accession>
    <name>A0AAV4SZT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger protein 418</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_16510</name>
        <name evidence="2" type="ORF">CEXT_532911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010477">
        <property type="protein sequence ID" value="GIY39540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12695" checksum="F1CD432202DF6133" modified="2024-11-27" version="1">MARHAGQIPTKRQFGSRLANRTYIGQLVKAGQPTGPRMQPFPIQPSPVSSQASTTSPLNSPTTPQPLPTPVQNNHPDIRSPHQGMGNPYSESPIDLKPPLNCHLPLSRPMSCNQTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T138</accession>
    <name>A0AAV4T138_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Stomatin-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Stoml3</name>
        <name evidence="4" type="ORF">CEXT_674801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010443">
        <property type="protein sequence ID" value="GIY39307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T138"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF130">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="142"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY39307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="466" mass="52488" checksum="14A28C2AF14A394D" modified="2024-11-27" version="1">MAKEVGRNNGILSRALPMMTPLLHINCNRSDHFVYLQTCNQCGVRESQSTKKRRKSIMVPKNGINSIFDYDSVFKYGPANINMKSYRKNDYKSVYTYHAVSISSDDENETTKETLLSVILRNIITFFFYLLAILSFPISFLICLKKVHSLERGVLMRLGKLQPIKGPGFVFILPCIDKWIKIDLRPQNFTVSTSQLLTADGGVVQVESNIEYQISNVLSYVMKLHNHEKTLKDLGLFCLKNVVSEKDLEDLESKKEFISCNLKDELNRSVINWGLEIVNVNLHSVKVLKAAEPVDAIGTIMSALKAATGSSTQHTAAFFPLIPDTVVEKNIDSKGSQHLSSFDARAHIKTGDCIEAVRKLANLAEREGYLKDLNAKFKFDLVGRSTRTFLISFEKGNISVLENIDDSIQSNVQLMLSEDNLKDFLNGEISPLEAYMDGKVMVTGDWSLLRSLAKVFDLCRSKFLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2E9</accession>
    <name>A0AAV4T2E9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_202191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010593">
        <property type="protein sequence ID" value="GIY40285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2E9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8433" checksum="834A3E196FCCC484" modified="2024-11-27" version="1">MAPLVWARPMWRELAVPYSQQREAFCARVARGRARPTSLVRRRTLPQRIRAHLAFSISWPFSAILTRSTIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2T6</accession>
    <name>A0AAV4T2T6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_663271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010612">
        <property type="protein sequence ID" value="GIY40435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2T6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11988" checksum="228759CE2EE3B213" modified="2024-11-27" version="1">MNVPIIRKSKTAISSKTSQFPKGSHPTFYENPEGTDRAYQQTLHPACRMMYLRNIKRPPRTTAAGMIPRDNDCKSSTRFRCITHTPVCVEKISRMSHYRCLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3H8</accession>
    <name>A0AAV4T3H8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_128871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010505">
        <property type="protein sequence ID" value="GIY39759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3H8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="18189" checksum="F29BE9BC01995C9E" modified="2024-11-27" version="1">MCHPNFEARVRSALAQLNKWASAGKAVCDAEEFSVKKRSSPLNHGDHHFNFDVMPISIIFIFPIVDDDYSIFLYSKFIRFCCHDDGYPYAASFIMANFPAFSVKVMCNLLESAPRQWMVCGKLLLSCIIRHKTLDCFDMFEEYMYCSDPTGRDQEPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T408</accession>
    <name>A0AAV4T408_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_249332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010539">
        <property type="protein sequence ID" value="GIY39971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T408"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12385">
        <property type="entry name" value="RRM1_hnRNPM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="38"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="188"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="457"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY39971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="526" mass="56138" checksum="9C23833D9A114E1C" modified="2024-11-27" version="1">MDGEKWSDIMAKQEQRDRRNNNRSRSPRGRRTRAPTNRRIYVANIPYDCKWTTVKDLFREKVGDVSYVELFEDENGKFRGCGIVEFKDSSSVQKAVDTLHRYEFKGRQLVVKEDFDVDRDKTGKPLGRIRGGGSGGGGGGGMGVNLERDRDDFGGLGNLGNNNAPQYNTYGLSPQFLDALGITGPLTSRVFVAKHYKVSIQKLEEVFKLAGRVVKIDLKRDEDGNSKGHGTIEMGHPVEAVQAISMFNGQKFYNRTMSVRMDKKHQEDPEDKRLPEGLQSVGKGLGANGLPLHLSNSTGVNNLTPTGIAPVAGLGGVGTNNLGLVSNQMTPTVVGANAAGIPGLSGIGMGIQERNFTNLGAGVGTGLGLGTTGAAGLGNPSLLPGGLGGMSNNAAGLGGGGGLGGGLGSTLTGGLGLSLGGNSVGGAGGLGYNDYDRSFDRVDDGYRNARKPLKWSDTLVVRNLPATYTWENVRDRFRDFGDVQSTQMKGRGTAHIRFSSEAEAARAFDRMQGTRIFGRLLDVSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9M0</accession>
    <name>A0AAV4T9M0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_244321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010731">
        <property type="protein sequence ID" value="GIY41612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9M0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11893" checksum="28498C3BB40B2DED" modified="2024-11-27" version="1">MSSKEFIRLKRLLELSLKFPSGYKKLDFQQHREHPNVSDEVCSNNDTQETSKYPVDVHQVFDSGPYPKCLNHTHSARLPSLYSWLTWLHHYPRISFDIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THL8</accession>
    <name>A0AAV4THL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TBC1 domain family member 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TBC1D19</name>
        <name evidence="1" type="ORF">CEXT_433212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011374">
        <property type="protein sequence ID" value="GIY46133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042507">
        <property type="entry name" value="TBC1D19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16110">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16110:SF1">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="258" mass="29567" checksum="CFF0CB5CEA6F518F" modified="2024-11-27" version="1" fragment="single">MDPDVSCDALEDQMRTLISDSGYKQKLRNLVYQYIVKDPNLRNEIQQRKEPLEYIQKAQINWEHRITKSLNNMSNELSLRPVSEQIEFEAKWSELGSEDMDLSRFRPVYSPKDFLEVLINVKSPNIGLMMSPDPGLSTYWGLIKVPLKVKTFHQLRLQFEEMVGNTDHLGLNILPFSNCDSSKKCLKERVSLGKARPGGGKACLAREFCKRGCPATLRADLWALVLGVDICGAHKLNFKHLKSCVFQHDLLIDKLIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJC1</accession>
    <name>A0AAV4TJC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_498401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011243">
        <property type="protein sequence ID" value="GIY45166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7718" checksum="291967881908DB46" modified="2024-11-27" version="1">MEIPKSPFGTKKLLYSLKLLEIGLSLRVIEIGPSPKGNGKWFTPSHFLRIMKISPPSKDDGPIPKDNGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMP2</accession>
    <name>A0AAV4TMP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_420151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011572">
        <property type="protein sequence ID" value="GIY47395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="48" mass="5053" checksum="74AE3442FADED441" modified="2024-11-27" version="1" fragment="single">SSSSDLNCSDSSSSDLNCSDRSTDLTCSDSSSSDRNDVIDLNRSRSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAF8</accession>
    <name>A0AAV4UAF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette sub-family A member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Abca5</name>
        <name evidence="5" type="ORF">CEXT_468921</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012554">
        <property type="protein sequence ID" value="GIY54773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="16"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY54773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="510" mass="57847" checksum="05295A334A25CB1E" modified="2024-11-27" version="1" fragment="single">MFNEIATVAKRSMMKFRGESLSSSDIQTAVKAVLKNGVSKHAEIGGIAATKNFEIVTDGQEKDTLRRELQYVNNSNFHYFIRKTLRDVDKKGDASISIDALEIMDRMLFTIFGDLAMVAKRIRIRAGYKTFTSLDIQTAASAVLKNGVSKHAEVHNWMEELDLTSCSSTLSIKLNTDQKRKLCVAIAAIGEPDVLLLDEPSSGMSPKARKLLWNVLQDYAKAGRAVVFITHHMDEAELLSGCLSNRSLFLRAKQCLPSLLKDLPSNPKIVLTTDTEIYVKLRSFIGTHCAEFFRKIEEHFKDITCNCFTISLFSLEDILYFASGKTKEDEAKCVRIPRKEEETGQNKSSIFHRKFTTLILYRKRLLLRNINAAFILVIPILLILVVKGKFYPKTPEPSLATIGPHLYRNETIHVVNETGKKSLAFLETSMSKLDVTFVIKNPTEKFQSKSFYYHEYSKNSKFLLAEYRSNRGEKVKSNPNSVFATEDPYVGNPLLDFEKKTMNPLNPHIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UGC5</accession>
    <name>A0AAV4UGC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Tf2-9_399</name>
        <name evidence="2" type="ORF">CEXT_803541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012814">
        <property type="protein sequence ID" value="GIY56821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UGC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="1">
        <location>
            <begin position="77"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="21529" checksum="0C3BEF30C552DE50" modified="2024-11-27" version="1">MDYSDGVSTLMWCGENKQDDYNRHILDISDDELIPPPGRDEIESAINKSPGGHLINQGILYVYAPDSDTEKAQLVMPSQERKSILKLHQDSPMAGHHGEEGIYQRIAQRYYSTGLRSYIANYVKDIISSASEPSRKKEELRLAILTSFVTISDSELNGSDSYVQVELPPELSRVTDRPFAQACCALSSKKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKY9</accession>
    <name>A0AAV4UKY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_662701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013050">
        <property type="protein sequence ID" value="GIY58370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7905" checksum="7480A13EBA8158B8" modified="2024-11-27" version="1">MKVATDVILARWERGGVEPLGHHCRCRRHGSRAGRHSGLRLLLQANLLGEEASGAYGAHIGRGNQHLQQSAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMZ8</accession>
    <name>A0AAV4UMZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peritrophin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">X975_16181</name>
        <name evidence="8" type="ORF">CEXT_606581</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013162">
        <property type="protein sequence ID" value="GIY59114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043764042" evidence="6">
        <location>
            <begin position="19"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="95"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY59114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18091" checksum="3B2A0473E4C38BF0" modified="2024-11-27" version="1">MVLLLLLFGLLSSAICGALPVQSGELTWSPRCPTSSRGKIPRLIPDPTNCRSAFLCYHGMPRRYFCPKGQVFDAQNQECVPKQVCSKENDEYTAFTTCPDRNGPKNILFPHPTDCKMFYQCDNGIAVLRQCAALTHFNPATDRCDWPHEANCKARYLTLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQC0</accession>
    <name>A0AAV4UQC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_461211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013256">
        <property type="protein sequence ID" value="GIY59933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY59933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7159" checksum="9895FAEA48DE739E" modified="2024-11-27" version="1" fragment="single">MGFGDLQFKWFPNVRAPDSGSQSLRRTKRRHERCPAGGSCISPSQGVMSGHGRGKAICVLRTLGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT52</accession>
    <name>A0AAV4UT52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-tocopherol transfer protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_08134</name>
        <name evidence="2" type="ORF">CEXT_24741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013399">
        <property type="protein sequence ID" value="GIY60916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="53"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="239" mass="27714" checksum="50508D33CEB5C688" modified="2024-11-27" version="1" fragment="single">ESKLVTPTDESFLLAFLRARKFNAKKAFKLLQNYWRFRKEHKNIYDHSDSTSVKQLILKPMMGALTYRDMSGCVVLLFKVGMWDPDLDVYEQVFRAVTAVLVHSIQFPATQVCGYRIIFDLRGLTWTQLKMCTPSNMLLMIRSTQYCFPARYKGVHIISENKLFNLVWAVAHPLLTSKLKKRIMFHGTDLAPLSEYIDPSILPVEFGGQADPFENTKWSEVLDECTHQVLDQLMYGYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY15</accession>
    <name>A0AAV4UY15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_225794_1</name>
        <name evidence="2" type="ORF">CEXT_175051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013643">
        <property type="protein sequence ID" value="GIY62634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007098">
        <property type="term" value="P:centrosome cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029327">
        <property type="entry name" value="HAUS4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16219">
        <property type="entry name" value="AUGMIN SUBUNIT 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16219:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14735">
        <property type="entry name" value="HAUS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="268" mass="31458" checksum="EE5D66544C458292" modified="2024-11-27" version="1">MLKAVNCNKLKQSENKSFSTESDAKIVELFHLNLLNKHISTNKSSEKLKFFEKCQTFIPEILETRIKAREALTSFTKQIENNINEFCKKLLKYHHKGNFPLKKWQKQFDAAIEELSDKSSLLDSATVKFNILSSILYKKMMQYYEELLEGIEILAKLMRLYQQKLDFQLSMAELSFEKGASIELKISTYSVEAVKALKIIKEQLNKKEDCLKSQLIKVNEQLEEYQMLGPEYEEFVKQYQLILENIEKQKWAIESLKIKTTSEERLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2C1</accession>
    <name>A0AAV4V2C1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_201801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013832">
        <property type="protein sequence ID" value="GIY64100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2C1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8786" checksum="08BB75282E26A802" modified="2024-11-27" version="1">MNVKLKDSCQVRRINLSCRIIKKEREDSFHRGEGRGSTEETGVLVMFEALTSHFVATFLLTLKEDESLDWIVDKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3T7</accession>
    <name>A0AAV4V3T7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_298991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013899">
        <property type="protein sequence ID" value="GIY64595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3T7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="32" mass="3540" checksum="2F64C5B82A0FA95A" modified="2024-11-27" version="1" fragment="single">MSKVSAAWKSSPIGTTTQQDPFTNRKRCSNDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V412</accession>
    <name>A0AAV4V412_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_65991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013860">
        <property type="protein sequence ID" value="GIY64305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V412"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8900" checksum="DDDB8968E82D71F5" modified="2024-11-27" version="1">MFPYAHTKSRGDKIPFNQNFEQNIFGEVCDRLPQRPKCQGEFSSHSTTHSSELKDPTPCIKSIGWLSFKRRGRISSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9B5</accession>
    <name>A0AAV4V9B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_757171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014103">
        <property type="protein sequence ID" value="GIY66273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14311" checksum="23EC06EACAC008E1" modified="2024-11-27" version="1">MISLQVVYVQIFRKILHPPRPTRLDLRELLEQSLSLIDNISQESLEIEHPPTSFYGEATGGGKRGAQGGLGTVGGTGLGQWYVELSGASGLSCFSETYCFSEMSARPADVGGGVIRVLWSLGAGEANVIDKVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9X4</accession>
    <name>A0AAV4V9X4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCY1-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_26866</name>
        <name evidence="3" type="ORF">CEXT_267971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014198">
        <property type="protein sequence ID" value="GIY67087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9X4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF6">
        <property type="entry name" value="SCY1-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY67087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8163" checksum="08F89FE38F4AB26B" modified="2024-11-27" version="1">MIHGNINPESILVNQSGVWKLAGFDFCIQLEKNPDFQNDQFSFGEINVELPPLCLPHLNYITPERIFGKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHF7</accession>
    <name>A0AAV4VHF7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_60032_1</name>
        <name evidence="3" type="ORF">CEXT_347041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014473">
        <property type="protein sequence ID" value="GIY68973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01099">
        <property type="entry name" value="PAN_AP_HGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052774">
        <property type="entry name" value="Celegans_DevNeuronal_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327">
        <property type="entry name" value="FI18240P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327:SF1">
        <property type="entry name" value="RE15579P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00473">
        <property type="entry name" value="PAN_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="56"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY68973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="21349" checksum="0800FCEBE799619B" modified="2024-11-27" version="1">MKGVVVARKGVASDPQTKKEGRQVPPEDLIEIKKRFQVARIYLSQTLEDTSNNIQCKRDWSFERIRNKELVGIDHEKVLVEANTKEECQEACLNHKQFKCLSAEFNYQLSECRLSPYNRFSSTEKGVAVSNSRFVVDYFENNCIEEPRGFCNTKLLKKYRLMITEKITQRGLHRRLSPAMLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJX6</accession>
    <name>A0AAV4VJX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014659">
        <property type="protein sequence ID" value="GIY70403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17153" checksum="B6451684B9C6CAE1" modified="2024-11-27" version="1">MVGRASSVRSRLLRPKSLSADGELLANLSFCFSRLRSESSRLTNNSPAAATSVRKILVTELEKWNRFFKGIWDTGVSSQNDYHYRCSIKVNGHCECAALGEMLFCTFYSSGKWIIILGIIHLRIVREALAPKSRTSPRSFAFFYGSSESKESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSW4</accession>
    <name>A0AAV4VSW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposable element tc3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RF55_24064</name>
        <name evidence="2" type="ORF">CEXT_570981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015088">
        <property type="protein sequence ID" value="GIY73492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326:SF1">
        <property type="entry name" value="HTH PSQ-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326">
        <property type="entry name" value="TRANSPOSABLE ELEMENT TC3 TRANSPOSASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19542" checksum="4993ED7C79FFE9E7" modified="2024-11-27" version="1">MKKIETTGSFASRQRSGRPLTAAAVATTVEQTVQSMSAVAAHGECSAREVSRQTGVSYGSVRKALRITLKRYPYKLQHKQELKPPDFDSRRDVCGRHFYVSKLEGRQAAITREHDIEVPPATHQLAQEDVATRFVLQERQEGHIPRNDDTQPLHLVVQRQNHSLHGQVGLPQNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTY5</accession>
    <name>A0AAV4VTY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_216721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015014">
        <property type="protein sequence ID" value="GIY72948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12584" checksum="06AD92AAA918536C" modified="2024-11-27" version="1">MPNLTLTEDALGEGKMNKKSLNFFFFHPTLQTNSSTSSMVKSNKEAKKGLHNLSCNSPLGLKTNCLLGDMELGLEYTVTSWTGSKHGDRERFKKFLGGGDSNSGWGGEIFDRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVQ9</accession>
    <name>A0AAV4VVQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015095">
        <property type="protein sequence ID" value="GIY73548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13321" checksum="103953A797980C66" modified="2024-11-27" version="1">MHITTELSCVFSGHIAIDPSYILSLHIITDPSSVPSMHITIESFCVMSVYITTEPFCVLFVHITIDSFCVLHMQITTEFSCLPSMHIATDFACVLSVQITTDPTGLAKNNFDDEICSQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VYE0</accession>
    <name>A0AAV4VYE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_591571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015279">
        <property type="protein sequence ID" value="GIY74964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VYE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20247" checksum="CCE682AABACEE7CD" modified="2024-11-27" version="1">MFSNDPSCPALMPLDEGSGTSELTTPRFVVPRHVTSPYAAPRKSAVSWPVHEGRQWLKSVPRTPGEPRNNRKKIKLFKTRSLSPPSLDICRRSTPRRAVISPVHEGACHGSKRSSSLVKRVLSFIKVSSIPSPAHSIPMLSQEYSFSERNAWNAYELATRRLRSTNSMQCFPHRDFYWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3L8</accession>
    <name>A0AAV4W3L8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_499071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015490">
        <property type="protein sequence ID" value="GIY76474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9362" checksum="70B5E5CEEDEB19F8" modified="2024-11-27" version="1">MNGIYNGIIIEISNGICNEIMNGICNGIMNEISNGIMNETSNGTCNGIMNETSNGTCNGIMNGIGNGIMNVISNGIRNGTSNGIMNEISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4L6</accession>
    <name>A0AAV4W4L6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_545671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015659">
        <property type="protein sequence ID" value="GIY77677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8424" checksum="C50944851594CA86" modified="2024-11-27" version="1">MENLIEKSRALTIDELLKYSPLNGAIPCSFSEKAESFTLLDRRGKRDVGTILMNPGRWPRTQMISVKPINRTCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9P3</accession>
    <name>A0AAV4W9P3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015889">
        <property type="protein sequence ID" value="GIY79447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9P3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8197" checksum="405B8FA87A0708D4" modified="2024-11-27" version="1">MNSSVEIHSYARYGIMLWFGISLNNYADFRLLCRRNTKTEKYWDKTLDPDVRYYSGTIGNKFNLMDDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WF11</accession>
    <name>A0AAV4WF11_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_597421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016099">
        <property type="protein sequence ID" value="GIY81227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WF11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15569" checksum="385E63B53418825D" modified="2024-11-27" version="1" fragment="single">VNPLRAPSTLTLSDLYLRVWTDSAFPSTNPPTTPLPRSIFKSNGVHCTFGEVKREKRQKYYVLNKGSSFFCSNFVVDASSVCFVLDSLYRERCFSYLWGRKDLPSFHKPLHPAKIPLKVQCGPSSPFKGTSHVYGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WF93</accession>
    <name>A0AAV4WF93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_66281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016134">
        <property type="protein sequence ID" value="GIY81475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WF93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="12417" checksum="E8529C9AC513130B" modified="2024-11-27" version="1" fragment="single">VVIFCAALTAAHASLVGPMGLGAPIMAVGPLSLGLGKGMIAAPVARIAAPSDSSEMVSSVTECSPTESSVTECSPTESSPETECSPTDSLPDTESPELLSLSEPDSSVPQSVSVWVLERPSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUR4</accession>
    <name>A0AAV4WUR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_760921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016806">
        <property type="protein sequence ID" value="GIY86487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12643" checksum="E7B6FDB8EAD09F5C" modified="2024-11-27" version="1">MCVALTPHSDGDVVGERRQVVALGLALEDGLVIGTGHCEGEDAASRDSTEFRTQRLLQVFAHVPPVPLPRDAGQGLLALEVHVRVTCNDCFLRPSTKVYIVWDTTKDYNFKPLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X6E1</accession>
    <name>A0AAV4X6E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">G patch domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPATCH1</name>
        <name evidence="3" type="ORF">CEXT_791311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPATCH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017199">
        <property type="protein sequence ID" value="GIY89373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X6E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011666">
        <property type="entry name" value="DUF1604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF19">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07713">
        <property type="entry name" value="DUF1604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY89373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="395" mass="44820" checksum="BC5B4F66BE07429D" modified="2024-11-27" version="1">MEEDEDDYIFYGTPLPEIEEESVLRKKAARELEVRDEKGRQRFHGAFTGGFSAGYFNTVGTKEGWAPSTFVSSRENKYNDHKQQNPEDFMDEEDFGAYGIATRRIHTTSKFKDSFDSRTNKRKFSEVDSVIPGEAPLKDIESIGIEILKKLGWKLGQGIGPRVKKMVSNVKVYGCSPFPEVIELEEDDPFAQSYTFAPEDTETELYKPKDNVFGLGYSGLSKDPVLSTHTISGQAFGVGAFEDDDEDIYTKDDMSQYDFSEMEPIKNSNAPDMKQQLNSLSTVLKGFCLASQPATVKKYYPPPELPHNYRPIHRTATKNVPQSDSKFKSRHSMSAEDRSLLIGEKKFQSFKLITEKKAFVGKSDVENVNKNLPKNTHTFCPFQMMSLSRKDMKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X6R5</accession>
    <name>A0AAV4X6R5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_186901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017304">
        <property type="protein sequence ID" value="GIY90234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X6R5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8324" checksum="D6B8A31D75F6F985" modified="2024-11-27" version="1">MDSSGPSVWNACSHFLQGLNRSISDLWLSQWATLQLASSCPSHEASRLSCRFSLVLLFRGSSLSSCLERFMENLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDN8</accession>
    <name>A0AAV4XDN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_541301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017581">
        <property type="protein sequence ID" value="GIY92747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10371" checksum="A8821D2203621FA5" modified="2024-11-27" version="1">MENSPASISRRLSSENDDDDDGRVTSREPRNCIYMVDGTPKAAFRMNWPQNIAAKKRELFATSFVIVSTQTLTEQFIKNFWYLLSDWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF83</accession>
    <name>A0AAV4XF83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_399071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017571">
        <property type="protein sequence ID" value="GIY92655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15518" checksum="7F3EBF61177C93E6" modified="2024-11-27" version="1">MLSFKKTTTSIAVTRTPYGLPSLCRGLNHLLKMVKTLRSILKAWREVRIIAGLSVFNIPPKLSGDSVTGQSATAEAPTSEKEADTCLKRRTPLITRTDHRPSPQRESPKRSVNSIESGRSADPFVRRGDCGQRVVSHYDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHT8</accession>
    <name>A0AAV4XHT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_480291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000259">
        <property type="protein sequence ID" value="GIY93333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12919" checksum="9984728CA72A307B" modified="2024-11-27" version="1">MLRRKPFDSGSTGEFSNLLFCGGGENLQKKEFLHIPVCVATARSSHASNWLWDLLLDWKSRAIAWCKMEMEMNRRDGIMVGMGPTPTTPQARWATRLQVQTLLSSIHPHSYSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJU2</accession>
    <name>A0AAV4XJU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_547541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000455">
        <property type="protein sequence ID" value="GIY94944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9371" checksum="77FE2339D76F0F62" modified="2024-11-27" version="1">MKEHWNGTGLLGQTWQSIFFINKQWKAMGWNDESRYTLGNLNEQVWTYDIHVGCYLSDYEPVALQIRVDYQSVLPCVNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLK8</accession>
    <name>A0AAV4XLK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_331211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017889">
        <property type="protein sequence ID" value="GIY95273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11711" checksum="E7ED4650F8E22669" modified="2024-11-27" version="1">MNIQKEDETSQTQNATLKEVVPLKIPLFLRFLQWWKKIKPLFERNRPQDLLFRTSEMASLSFKIGVSRNRSRIVNKPVDVEMVGEMEKGYKYGQDFIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMN4</accession>
    <name>A0AAV4XMN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_635861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000470">
        <property type="protein sequence ID" value="GIY94998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20835" checksum="EF4E590AE380BAD1" modified="2024-11-27" version="1">MQKTWYITFKFCHYTFGITFPGMLLLEKEYSTKRYIDSRPYKLIFRSKILDEIVKGCLSVGFTFSFLHQTRRYFNLQVYSSDSYFTRFLIQVQWVRNTTCSPPSLLGLYGFRQSAWRGMSPELGIRMRRATRLIHMDDAFDIGIMAHHSARVDGGHYFVFRNVLGREDFFGEVGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XS79</accession>
    <name>A0AAV4XS79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_15691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000677">
        <property type="protein sequence ID" value="GIY96588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XS79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16798" checksum="1FF9A6D03ABFC855" modified="2024-11-27" version="1">MIAFSDLCEKRKPIKRPYFSARNHIGRASTDLQISGYRAVVCSDRKGWKRHITRGKSICFGRPTSRNAGLREGSAFKLAWEDSLLSLMHHDSNLKKMLRQSCGTSEECMPPPCSYESPAEIRVIVLSMSPTRQQYELYNQAARKRNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWX9</accession>
    <name>A0AAV4XWX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_226031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001074">
        <property type="protein sequence ID" value="GIY99651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9726" checksum="68F500A4295D4A6E" modified="2024-11-27" version="1">MYRLNTSETANVANVVNTSTLVKPAHNLKYKTKLYTSHGCTFRKCHAQDRERQISYQKPTMDRVRNSTYLKGAHINLGKARAINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5Z8</accession>
    <name>A0AAV4Y5Z8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 4V2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Cyp4v2</name>
        <name evidence="15" type="ORF">CEXT_679981</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001365">
        <property type="protein sequence ID" value="GIZ01904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5Z8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000035">
        <property type="entry name" value="CYtochrome P450 family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIZ01904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="909" mass="105678" checksum="4DF76F7DFB2A8644" modified="2024-11-27" version="1">MDFLFNVIFHQVLNGYNSMYPKDQLFCFWASYAPFVLLQKAEGVEALLSTGLLTSHGSKWKSRRRLLTPSFHFEILKDFLPIFNEQSQVLVKRLQKETTKDSTDIVTPITLCSLDIICETTLGISIGAQENKESQYVKSVTRAGEIILERMFKCSHWIDWIFFNFIAVGKELKYHIKVLHDFTISVIHEKKRKLLSGDSEIDTKRKRKALMDLLLEHHLQTKDLTEEDIREEVDTFAFEGHDTTAMGMSWALYLIGLHKNVQEKIHEELDRIFGDDVERHADTNDLKDMQYLDCVLKESQRIYPSVPLIAREITEDTKICGYSIPKGTSCAVHVYLLHRDETVFPNPEKFDPDRFLPENSLNRHPFAYIPFSAGPRNCIGQRFAVMEEKIIVSAVLRNFTLESLDQRDKLPPAPELILRSSQPIRIRIRPRQRLHTGLNILGNLTDFPWTKFHKNGFSFNVFFLQVLSGYGSIFSKFQLFCFWTSYSPFVIFQKAEAVEALISGTKYMKKNWSYNWLHPWLGTGLLTSHGTKWKSRRRLLTPSFHFEILKDFLPIFNEQSQVLVKCLQKDTTKDSTNIVEPITLCSLDIICETTLGVTINAQENSESQYIKSVTRAGEIIMERMLNCWYWIDWIFFNFMEDGKELKNHLKILHDFTLTVIQEKKKKLLSGDPEIGTKRKRKALMDLLLEHHLQTKDLTEEDIREEVDTFAFEGHDTTATGISWALYLIGLHKNVQEKIHEELDRIFGDDIERHADTNDLKDMQYLDYVLKESQRIYPSVPIISREAPENINICGYSIPKGSSCTVHVYLLHRDETVFPNPEKFDPDRFLPENSANRHPFAYIPFSAGPRNCIGQRFAIMEEKIVISTILRNFTLESLDPRDKLPPAPELILRCSQPIRIRIRPRQRLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8D1</accession>
    <name>A0AAV4Y8D1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_84201</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001580">
        <property type="protein sequence ID" value="GIZ03278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8D1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043539993" evidence="4">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ03278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16688" checksum="51185B1ABC623A5E" modified="2024-11-27" version="1">MISVAWTLYMLGLYSEVQAKVHEELTGYFGEDVDRHATLDDLKDMKYLITTWLLLSILVYNLTTLTDLVNSFTTCLQVVIALAERLFEVTSLRSTDPTGSASSCSLNDALGSSQTLRPPPKSLMGGYSECSRLSNETSNTVSYLRASDGAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8N6</accession>
    <name>A0AAV4Y8N6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CEXT_126051</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34935"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:34936"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>tRNA(Gly) + glycine + ATP = glycyl-tRNA(Gly) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:16014"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01001584">
        <property type="protein sequence ID" value="GIZ03289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00935">
        <property type="entry name" value="GlyRS_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.230:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00762">
        <property type="entry name" value="WHEP_TRS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="17">
        <location>
            <begin position="72"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="16">
        <location>
            <begin position="269"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIZ03289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="508" mass="58445" checksum="5F7FC182A1B5F32C" modified="2024-11-27" version="1">MVFFGSRSRIISWLPVLLYSDHVRRCYRPCITFLHPYSTERRRLPNNWGKKKLERIKLHFMRNMDDPTTQNILQPFRLAVKEQGDLVRELKANGAPELDVKKAVNELKLRKKALEDKELAPPEIGFDRARMEDLLKRRFYFDQSFAIYGGVTGQFDFGPMGCAMKNNILNLWRSHFILEEQMLEVDCTILTPENVLKASGHVDRFADLMVKDLKNGECFRLDHLIKAHLEKLMTEKNVTPQQIAEYEDIIVKLDGYSKDEMNAILRKFDMKSPNTGNDLSDALEFNLMFSTSIGPTGNLKGFLRPETAQGIFVNFKRLLQFNQGRLPFAAAQIGNSFRNEISPRTGLIRVREFTMAEIEHFVDPRYKEHPKFKQVQNLKLTLYSACNQMNGESAFISTIGDAVEKGIVANQTLGYFMARICQFLVTVGVTPEKLRFRQHMSNEMAHYATDCWDAEIKTSYGWVECVGCADRSCYDLTQHTKATGVKLNAEAQLKEAISFDCVHDKYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCC7</accession>
    <name>A0AAV4MCC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_560551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019648">
        <property type="protein sequence ID" value="GIX70093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12122" checksum="73F11A85D5C4B82E" modified="2024-11-27" version="1">MATLIGQALIRRGLKKNSIIHPCAAKHERRRTPNNCISGNEVKRGAVGEGGGRTTDRHTKTTFLPLFSPNLLVSQRWYGNSAIRRLVTFGILFCSSASNVCRHEYRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MK65</accession>
    <name>A0AAV4MK65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_318821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019732">
        <property type="protein sequence ID" value="GIX71189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MK65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7734" checksum="777C0E4E9C497239" modified="2024-11-27" version="1">MIPPKAYPPPTTSYADSLKKPSTTERNKGITKNKIIKKHVTTVKPKAENGSSIDTERRSRPNWISEPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MK69</accession>
    <name>A0AAV4MK69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_560341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019829">
        <property type="protein sequence ID" value="GIX72240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MK69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8474" checksum="DFB5BAE5832BF500" modified="2024-11-27" version="1">MSWDAAKEKKLQRSSAQYDIRRALSMVPSQCSRDRIIMDKSLLSCYSCEGPGDIKEKCQNPTVQGDGVNRQHLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQG3</accession>
    <name>A0AAV4MQG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_92961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002520">
        <property type="protein sequence ID" value="GIX74671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9382" checksum="4EF56650E0E76BF2" modified="2024-11-27" version="1">MFVVELDTKSSAPNKAPELSSRRNFIINELQSKNDALTHTLQINYFSLLALHPALINGRRAKGKRITGLCLLQGERLYLSSGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR54</accession>
    <name>A0AAV4MR54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_686141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020102">
        <property type="protein sequence ID" value="GIX74843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11441" checksum="D166528D15D04DE1" modified="2024-11-27" version="1">MPVPAKVPVASALKVFRCFVQLVFNTEYLNGFLLQRVQLLLCDDHLARVPFVQWYLQQRTQNLNLPAYVFFIEAAFNRDSVFNQHKEHFCLRRISIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MV43</accession>
    <name>A0AAV4MV43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002610">
        <property type="protein sequence ID" value="GIX75680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MV43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11198" checksum="926E57C98D39BCF4" modified="2024-11-27" version="1">MTYLFNPKVPEIASAAVLAFPGSLSRSISNRVENICPPPDRLNQLPPCYWGKSFGGRKDEWQNIFPASVKLKNKIDTLDFTTLLNITLNVSYSFFWGADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX83</accession>
    <name>A0AAV4MX83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_429241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002639">
        <property type="protein sequence ID" value="GIX75972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9113" checksum="E058715B18C45371" modified="2024-11-27" version="1">MSTPQAEITIFTPLVGFLCLRNRNKSDFSSNSRRRHALVGNEGIPPHTTSTICADGFLRGKRIPKLLPIGREEEFFNRLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYS0</accession>
    <name>A0AAV4MYS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_48011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020231">
        <property type="protein sequence ID" value="GIX76139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7826" checksum="D3A501ECAD00C96E" modified="2024-11-27" version="1">MRIFPLDTKLASFHTNYFDITLFDGKLQNAFHSGSETADLERFSKGVPSEMNFCIGSLILAPITFALKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N409</accession>
    <name>A0AAV4N409_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_33931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020400">
        <property type="protein sequence ID" value="GIX78312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N409"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12406" checksum="338758F2FDC3EA92" modified="2024-11-27" version="1">MTCEAVPTHLLDSNGITFLPPSPPFFLLAYKQKRSVRFCQSGLKSVFLWIDNPALTRREGIIPSEIDVSRATLSIYYSIEAKICERFRVTLFRCFRSLRLYVITDPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6I5</accession>
    <name>A0AAV4N6I5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Neuroendocrine protein 7B2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Scg5</name>
        <name evidence="9" type="ORF">CEXT_554972</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 7B2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003017">
        <property type="protein sequence ID" value="GIX80323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6I5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030141">
        <property type="term" value="C:secretory granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046883">
        <property type="term" value="P:regulation of hormone secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007945">
        <property type="entry name" value="Secretogranin_V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12738">
        <property type="entry name" value="NEUROENDOCRINE PROTEIN 7B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12738:SF0">
        <property type="entry name" value="NEUROENDOCRINE PROTEIN 7B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05281">
        <property type="entry name" value="Secretogranin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX80323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20486" checksum="51195A5AF8188DA3" modified="2024-11-27" version="1">MTTGQSDLYSKTTTPEIIVLKKLRGAGEGHQRLKPDGSMTNMKIVKTDTVLPAYCQPPNPCPIGYTADDGCLEQYENSAAFSREYQQVQICMCDSEHMFDCPGSTRDNELDALARSFENEGFMESTLDRFFQDMEIRDGHKIVAKKFSPTRHSSSFSLLRKRKELFLTYKFNKSEQEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGT6</accession>
    <name>A0AAV4NGT6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_245931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003339">
        <property type="protein sequence ID" value="GIX83535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043427866" description="Secreted protein" evidence="1">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12803" checksum="D445DA9C8508B90A" modified="2024-11-27" version="1">MMRMFLMMINMCMSMVMMTMMMMTMVMMLMMVALAWCPCSKSMMISYIVDLPVNALVVSKTVASPGHDRGHLHVHVYVEIHGGPLCHTQTCKVEDDGDGAVNWKFSKSGSTLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK50</accession>
    <name>A0AAV4NK50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_81971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021031">
        <property type="protein sequence ID" value="GIX85187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10058" checksum="B2C5F6A563061D34" modified="2024-11-27" version="1">MLEDGLNVIQLGPDDPFIHASPEDCLERFRRNESTQNAILFSEISPKVTLKLSHRIYKIGIDVLQSTVGVGQISLLQGRAAQPHMAKHCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NN16</accession>
    <name>A0AAV4NN16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitin-binding type-2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_263351_1</name>
        <name evidence="3" type="ORF">CEXT_75251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003570">
        <property type="protein sequence ID" value="GIX86182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NN16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043697042" evidence="2">
        <location>
            <begin position="20"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX86182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="421" mass="47749" checksum="DFBA5F1804438118" modified="2024-11-27" version="1">MLVLSTLLILCPLVSLGRCQFYNNYDETDPKEYQTGWEEPVNRNPSGEVERIRYVPEQNQVPQRSGQRTAAATSSDYNQDVQPQRRRIRKYRKILREGEYIQPPQPPVTYSPSVFENIRLGEAPNGVYIPQDSFLNVLKTPNYNRDSPSNHYQVPQSASPYVGNYGTSWQNSEPEYKFFGQPSSSPALPQQNVAPTIVQPNVMYSPINSQYHNAPSERISTRTLNKQRNQRRPGRMEPVVDIDVLRTPPDIMVDVQSPPQVLQMTEPRSVTKSPRRRTRVRNYVEPTYQPPKVYGPSAFQNIGLGEAPAGVHIPEDSLLNILRDPSRPQSNPRYTSTDLQPSSSGADIAAKSSYQPVIPEQPVSTRRQSRQRARSSRISYSSHSNDQESVRIAPASSQNQRSRQATSNNSATNRRQRMNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ67</accession>
    <name>A0AAV4NQ67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_96851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021144">
        <property type="protein sequence ID" value="GIX86460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9452" checksum="88E19AAE0FA6274C" modified="2024-11-27" version="1">MATYAPNPHPHPTQSKNLLKAPCFLSDKMESNIGPRTKRRSKAATVQKKSVIIQMGNGGRLQDWQECDKSFAKKIIQRQIWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRI2</accession>
    <name>A0AAV4NRI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_552361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021249">
        <property type="protein sequence ID" value="GIX87595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9037" checksum="4C0F7F2C60631291" modified="2024-11-27" version="1">MGTLFITQCAYMTFGTGHLGMGGLGMVAVSWPFKHLIYLLLIFVYGVPSRAFFCETLLDSDISLVSRITLAHHDPRIVQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSC0</accession>
    <name>A0AAV4NSC0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-carbonic anhydrase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_93201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021212">
        <property type="protein sequence ID" value="GIX87180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11856" checksum="036FA9D9ACAA8666" modified="2024-11-27" version="1">MRFGLACLSRASKRNNPVLDPIITSLPKVAFPGKEVAIQPFPLYNLLPKDVLHYYRYLKKLFAEFGNRPVLRRMSNNVRPTQDLNDRIVLESVPKEEEEDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWH7</accession>
    <name>A0AAV4NWH7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_109312_1</name>
        <name evidence="2" type="ORF">CEXT_16851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021293">
        <property type="protein sequence ID" value="GIX88100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="19316" checksum="59F1B9DF9297B169" modified="2024-11-27" version="1">MTYGGAAAELKVKSKKKETRQEGVNRRNTNPFKTGVANLSSKCLRNLTIDREAKDTLALCVYRFGKEVASKATETYGKKEDLQPLDLKHILSLYFENKAFNAAVNDANRCLALYENGLMDFKLKKRTMWTGDFSKEQFADCFTSAIKRTFLEIDPLSQLHSMASKYLGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6F3</accession>
    <name>A0AAV4P6F3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_173041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004139">
        <property type="protein sequence ID" value="GIX92593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6F3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10663" checksum="05881172681E8A06" modified="2024-11-27" version="1">MIRISIKYLKHLTHSLLKGPSILRLGNLPCTFPILSLYSVIERGKNENHKVNSFRTIFAAVGINECEVEEDKKTSGALKFDDEKLCLFSGRGGAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PD61</accession>
    <name>A0AAV4PD61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_664691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004474">
        <property type="protein sequence ID" value="GIX95125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PD61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12860" checksum="B795EC73D904DF0F" modified="2024-11-27" version="1">MCVGLRKWHGDTDIVVNFRSLKMYVHLEQKTNFEEEENFLISRIQSTSETDPVQSKCYGAKKFFNLHPDIHSKQTFSFLPLGPGGLFMIVVSIESSPLMSMRKVYFSWIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PK32</accession>
    <name>A0AAV4PK32_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase family 92 protein</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVEN_171520_1</name>
        <name evidence="9" type="ORF">CEXT_505131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01004657">
        <property type="protein sequence ID" value="GIX96528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PK32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF69">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX96528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="290" mass="34213" checksum="7B3E3F3EC97E8C4D" modified="2024-11-27" version="1">MLILLSTMEHLHSLGNKWQRLQDSDLFIYSAYEDNRIRDTVYIRLLAMSKGKFNEWNCTFSWEQIRLQSINTTCIQRHSDAADLRDSGRVTIIEHTLPGLSPKNAQDLDEILTRDVWQKRRHEMLVYNDCFYKHIKSLKYVVNIDLDESIIPLKHQTWMTLLEYVRTQNFKILHSASISVPNVYFFENFADESNASLPKYFNMLRHLRRSANFTPPGFAQKSFFPTQYALTVANHYALKTLHPNIRTNTVINKNLAQMHHYRASCPPKMEKECQEKLHEISNKRSNFTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQQ6</accession>
    <name>A0AAV4PQQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_714531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004793">
        <property type="protein sequence ID" value="GIX97527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12506" checksum="97BBFDA449DD44E1" modified="2024-11-27" version="1">MELNSKPESPCSSPNFDLEHFIQAERHSIRIASSILFQFRKCANISNFKSVCSAMLAVLTMGTSILGAYVTRDQKSTENCDRSSHDGMAFGGIQRTRITAILDHVFLFIYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PS66</accession>
    <name>A0AAV4PS66_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Short-chain dehydrogenase/reductase 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Retinal short-chain dehydrogenase/reductase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SDR16C5</name>
        <name evidence="14" type="ORF">CEXT_729301</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005057">
        <property type="protein sequence ID" value="GIX99529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PS66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052650">
        <property type="term" value="F:all-trans-retinol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000131">
        <property type="entry name" value="Short-chain dehydrogenase/reductase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX99529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="323" mass="35517" checksum="1C82B68980C5DBDB" modified="2024-11-27" version="1">MTNSAHKPVATAQEKCSGFSTLRDFVVLVGSILWCLISSAFSVVFQTKPKKSLKEEIVLVTGAANGLGKELALKFAKEGAVLVLWDVDEKGIQNVSSEIKSRGGAAHAYLCDISDNDQVQQVGKRVQQEVGDISIVVNNAGILQNVLFTDLDPAKIRKTLEVNVLSHFWINRFFLPRMIDNGKGHIVATASVAGLQGWLYLTDYSASKFAILGMMESLEEDMRHLGLSDRIHFTTACPITINTGMNQNPTTRLPSLVPILKVEETAEIIVHAIQRNEETGYSAKELTSSPLVSQAISRKVAQLIFDFVEYNQLPNSQEKQNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PVC6</accession>
    <name>A0AAV4PVC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_624651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005156">
        <property type="protein sequence ID" value="GIY00209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PVC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9550" checksum="D9F4A01CF91817B3" modified="2024-11-27" version="1">MSYARVHRLQQEFSSAIERGIRHSGNLWSGLHKNVPRKPFAFQFGSDQPEHLMSDARVLIACSAIERGSDDPESSLSGVNKNVPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXN9</accession>
    <name>A0AAV4PXN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CCR4</name>
        <name evidence="3" type="ORF">CEXT_389541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005440">
        <property type="protein sequence ID" value="GIY02393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048821">
        <property type="entry name" value="PDE12-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF37">
        <property type="entry name" value="2',5'-PHOSPHODIESTERASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21171">
        <property type="entry name" value="PDE12-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2',5'-phosphodiesterase 12-like N-terminal" evidence="2">
        <location>
            <begin position="140"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="274"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY02393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="561" mass="64623" checksum="E6208CFCDDA5BD77" modified="2024-11-27" version="1">MRVPFSLIFNRAIPFFRRYSNFSSKNNPTIKVLSDESNISFCFYYFNNVLKLGFPKDEKLEVILSSIKRNAELQHKKEIIKQYYATGAKSIEKNTVKDIDVCLMQNDCILDCNISNCEAWAQASTLCIGDVIYEVSFNTPTVKSLNLPDFLISGCVLRPHFILECASQNDSIFTWYRSIPEDYGKSLLSNKNKEILLENGKYWEKIHEGYVYFITTEDIGCFLKLICTPMQNDRAGPDCSVESKTVVEAAPEFPFEERQEHTKHFCDDESIQCLTYNVLAKMYVEEKKFPYASTKARDHYYRKQVLLKELIGYSSDIICLQEVEERLFERDLEPVLNLKGYSELKRNYDVLLNRIIQKSKHIYDGLLSKVSANIKDLNKLLAQNTVLQLLIVEHSHLPGTELLIANTHLYSNKDNPEVRLLQAAVCVYFIEYIIKSKGYQNPGVIFCGDFNSLPNSTTYNFLMSGKYECCGSWNKDPNGNNTMLEHNLNLDSACGTPEYTNYTASFMGCLDYIFYNKDILKVTDVVPMPRHEHVIAQVGLPSEYFPSDHIPLICKFQWKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1S4</accession>
    <name>A0AAV4Q1S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_404211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005394">
        <property type="protein sequence ID" value="GIY01985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15685" checksum="6ADFB2881778AC53" modified="2024-11-27" version="1" fragment="single">GKKNIFSDLMRLHFRLNLQETRKWALNHKFPARKSSLITTKERLEQETTPNLIPLTCVNPTLPVLIRCPEGQRLCVHQREGKEPSLLSTQLILIIRLRLRFWQLTIERKWEEHSFVYFYLINHNCSLEIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6U6</accession>
    <name>A0AAV4Q6U6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_287631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005815">
        <property type="protein sequence ID" value="GIY05190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13828" checksum="21D01C945D9D7483" modified="2024-11-27" version="1">MKCPVVSKGHTHGGGCLFEKRDVSKKWLFQHAVPVTPPNNALHLLSTLPERDSLLNALGGPVWVAFNHSKLDRVALMGRREESVQPTQSRDYWLPGGWDICIHTPFAFFRSFLDFSFGFFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAS0</accession>
    <name>A0AAV4QAS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_41011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005937">
        <property type="protein sequence ID" value="GIY06205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10977" checksum="644A4E8C5142C762" modified="2024-11-27" version="1">MCRQSESFHQDHLNLCELMNHFTNAEVGDVHIVYDIVNKNGCAVVPLCHEMFVTDCGFNTVGLHRMGNFGTEYLGNNGLERHSLHGCSLRSSTGFHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBH7</accession>
    <name>A0AAV4QBH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_459211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005872">
        <property type="protein sequence ID" value="GIY05706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12627" checksum="0EE0AC1EF6316784" modified="2024-11-27" version="1">MNAYKRNPEIVWRLRLRNWRHSLIDSCRLNGRAREPFDARSSPEGKQQVASAYFSRSVAYRKEPELGMDTRMFVWVKFNHLFGLYEREIDSKHGCKEAQILAPKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDQ5</accession>
    <name>A0AAV4QDQ5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_150571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005957">
        <property type="protein sequence ID" value="GIY06417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043405530" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9947" checksum="933353C12CBE94F2" modified="2024-11-27" version="1">MLLSQSIDGSFFFLFVFTLVIGCETLCEEEEEWLKMERTEVPFAYASVNLLHGLNWVQCRENICKPSRTGEKTKNEILREELSGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJI8</accession>
    <name>A0AAV4QJI8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_166161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006242">
        <property type="protein sequence ID" value="GIY08417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043820054" evidence="1">
        <location>
            <begin position="23"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19085" checksum="BA8CD26447DBC9D5" modified="2024-11-27" version="1">MKTDLPMFLLLVLECRFYLIFNNLVNQEILPLEREQPPCHNDKIKAIDDLDRFPRPTTLPATYLQLFILIDKLFHTIKKYILTVPSPIIMSHQRWDFSCVSSLPVNSSKQSGQRRSPTIGNLIITTPSFLVMGGCSWIVAAAEVEGSSCVGTRGLCMGGYDPSGNDISTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QK02</accession>
    <name>A0AAV4QK02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_810701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006420">
        <property type="protein sequence ID" value="GIY09735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QK02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11121" checksum="9B2FE2A9B0BB5E37" modified="2024-11-27" version="1">MIASDCLRVKLRGKFADTSDCIFEEAPPYLQMVVLRHRSHTQPRKVPLPHLRSMKRSIPEEIRRQRLSKQAKREKITSWFGVTKTPTRHQSLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT27</accession>
    <name>A0AAV4QT27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_252291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006623">
        <property type="protein sequence ID" value="GIY11255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13862" checksum="DB0C67E941EEF375" modified="2024-11-27" version="1">MANVLFVFPGNETQQRKCLFLIYFAGGPHKIHLGDSSPPSPGSSEILNYRIGAVLVLLNNNNNSRPDYVRNTSDEWSLRNPLVTERDPPRRRTNSERSDHRKAMEALLFGPNLLTRIATAMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZF1</accession>
    <name>A0AAV4QZF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_470901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007232">
        <property type="protein sequence ID" value="GIY15413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12929" checksum="90F8B7693996EE6D" modified="2024-11-27" version="1">MVGRLLGATDEEYQRPSEKNIGQGPFDFRRAHNNDDRARMCLKQANDWKEYLLQLRIAHNFANPSSERNLKSGDIVPVEGHKKSKIIWYMGVVEKVIVGRDDHVLFAHPKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1Z6</accession>
    <name>A0AAV4R1Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_193763_1</name>
        <name evidence="2" type="ORF">CEXT_482501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007360">
        <property type="protein sequence ID" value="GIY16343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043371739" evidence="1">
        <location>
            <begin position="21"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16059" checksum="C57784B0E18EFC86" modified="2024-11-27" version="1">MKLVMKFFVILGLVIATALASSDVTPPTLPLQNYSAVAVEQKFNGGCQGNKTYDYFADCGERCQEYPKYCSAEKVLRCGCLKGYVQIDSTFLSPCLKPEDCPQKAPVLKDKNIMKHMKKMQKHTLKAVKQAMKMEASLHSAENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3M3</accession>
    <name>A0AAV4R3M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_571481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007388">
        <property type="protein sequence ID" value="GIY16528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12186" checksum="1ED50CEE10FA6642" modified="2024-11-27" version="1">MNNRFTASLQSIPRSGTTSLSVSGEEKRKKSGPRDSPVAVSRRCGSRASRGRRWKGWGAHSGREGLYPHSEQCREASILQLKWCRASWASARERERERETGVLGRTAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9L8</accession>
    <name>A0AAV4R9L8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_414681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007629">
        <property type="protein sequence ID" value="GIY18469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="14"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY18469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9914" checksum="73781E0D5AE1CE94" modified="2024-11-27" version="1">MNKVDVLKLSLLLQGIPYAQPPVGNLRWKKPFHCGQMHPGATLRIISKTSFGSPCFQLNPFLKQFEGQEDCLYLNVWTPTLDPEVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RC82</accession>
    <name>A0AAV4RC82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_231241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007700">
        <property type="protein sequence ID" value="GIY18952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RC82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11175" checksum="081E345BC5A3C9EF" modified="2024-11-27" version="1">MCVLSCGSLWAEYSRLIVGENVESLAVNVHEEPYPGGHSLTSEDLAADKGNKIQEADDLKLQQLKTKLFESIATEDEGCYMRVYSRQYSIQGRSSSNQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4REC7</accession>
    <name>A0AAV4REC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_768541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007659">
        <property type="protein sequence ID" value="GIY18671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4REC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11641" checksum="D5BD3E943FC9FB19" modified="2024-11-27" version="1">MVPLDIHSKHIIISDSDYEVTFIASDRPGTFQSQSRHPHIIPYHSRIQCIISSPAPSIMTGHPMPHVVKESSERDILIWAIYSRRPFRRYRRGVCLSRCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMB2</accession>
    <name>A0AAV4RMB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Orct</name>
        <name evidence="7" type="ORF">CEXT_247421</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007975">
        <property type="protein sequence ID" value="GIY21168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17317">
        <property type="entry name" value="MFS_SLC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="29"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY21168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="482" mass="54609" checksum="67CEA27788EAA6B7" modified="2024-11-27" version="1">MDMFEVIGSFGPWQRRVFILFFIINIVGMWQNLAITFFAPNMDFRCVEPSYEEDSWTNETVFDNRCEVPANGSNASVPCTKWEYDTSFYSQTIVSEWDLVCGREWLISLTKSVYMLGFLISVFVFGQLSDSIGRLPAIVISYIITVISMLLTLLSNSFVMFSVLRFLQALGRTALTTVGFVLIMEMTGPQHRTEVGIGIQLGWSIGFTTLAAVAWFFRHWFWFQLALSVPILPILFFYKMVPESPRWLLSKGRTEQLEKLLTKAAELNGKEIKGKQKRSTETILYVFRWPRMRNRALNVNYLWVVNSFMYYGLSFNTNDLAGNPYLNFFLAGVLEFPSYVVLFWGIKKWGRRPTLIALMMVGGTACAAIAFVPLKLSWLSTSFAMVGKFCVTGSFGLMYLYTGELFPTVVRNVTIGSCSMFARIGSVLAPFVRELGKATHPAVPNILYGLLALSSGLLAFLLPETREQKLPDTLEEGENFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPU6</accession>
    <name>A0AAV4RPU6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">polo kinase</fullName>
            <ecNumber evidence="3">2.7.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">plk1</name>
        <name evidence="18" type="ORF">CEXT_166861</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.21" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01008335">
        <property type="protein sequence ID" value="GIY23983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14099">
        <property type="entry name" value="STKc_PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000727">
        <property type="entry name" value="Serine/threonine-protein kinase PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000091">
        <property type="entry name" value="Serine/threonine-protein kinase PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF93">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="23"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY23983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="359" mass="41576" checksum="323AEF2BB3C30B60" modified="2024-11-27" version="1">MSDRMKHEEVKQSITNPKTKVTYRRGCFLGKGGFARCYEFKNTATGETFAGKVVSKTMLLKPHHKEKMFQEIQIHSTLSHQYIVHLDSYFEDESSMYIILELCRKRSLMEMHKRRKTLTVPEVRYFMRQIVLACKYMHDNKVIHRDLKLGNLFINDDMEIKVGDFGLATRINHDGERKKTLCGTPNYIAPEILNKKGHSYEVDIWSLGCIMYTLLVGSPPFETNTLQNTYKKIKKCEYYLPPRLDRNARQLIQKLLHPDPDLRPTSDDVLMDDFLISGYIPSRLPTSCLTMQPRFSRNMSLCEVSNIASVTRNPLADQVNIPKTIPEKATVPATTEIEKLLPQLMKSLRIRVVCLRITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQD2</accession>
    <name>A0AAV4RQD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Platelet-activating factor acetylhydrolase IB subunit alpha1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PAFAH1B3</name>
        <name evidence="3" type="ORF">CEXT_492411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008265">
        <property type="protein sequence ID" value="GIY23339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01820">
        <property type="entry name" value="PAF_acetylesterase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11852:SF0">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="106"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY23339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="264" mass="29766" checksum="32030F467F191E1F" modified="2024-11-27" version="1">MTSYNILMTAYCMNISFGTEVRIRYLSTSYILKCHYLFIVSSMNPAVEATPPEDKRGDDRWMSMHKRFLIAAREQEPDVLFLGDYVVGMAAHTEMWEKLFVPLHCLNLGIAEDETQNVLWRVQNGEIDATDPKVIVLSVGSNNISHSSEQIVAGILSCANAIIEKKPNATLIILKLLPCGRQPNPLRAKLLEVNQKLKAACQGLANTQVIDIDPGFMQPDGYISHHDLYDYLHLTRSAYSKSFEILYDLLQQILTDSVDAQETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZP0</accession>
    <name>A0AAV4RZP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_190651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008573">
        <property type="protein sequence ID" value="GIY25760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13150" checksum="A596B2E4CD8226EA" modified="2024-11-27" version="1">MDGDTSSGRAHLISKAIPHLVSYTSSGDTSSGKRHLIWKATPHLRPHLLTSSAKIHLISKVTPHLQGDTSSPNDTSSSKLHLIWKATPYLLSYTSSGKLSDLEDDTSSANTPHLEGHTSSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8M3</accession>
    <name>A0AAV4S8M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_415591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008984">
        <property type="protein sequence ID" value="GIY28790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8750" checksum="604928D3E5540512" modified="2024-11-27" version="1">MFRPEAESNEAIIPTQISWNGRNCGLIDVPNSMMIDVPNSMKIDVTIIVSNGMMVDVTADVPNGMMIDVTVDLTKWHDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAF2</accession>
    <name>A0AAV4SAF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_363181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009347">
        <property type="protein sequence ID" value="GIY31258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="17907" checksum="6A7FD02681C96C72" modified="2024-11-27" version="1" fragment="single">LTPEVPSSPAVESKDVNATAEKVSPEGMCRQLSTAFKEMDVIDSIVANSKRSDLQQDYVQMTETLLQKRQFLEEWVSRFRCPIESCKLHNSTKIVVNNSNCKNLNTVNGCNVNNVVNSNTGKNVNLVNAINSNKVNGNVKTKTKRNASQISSNTNDSGNSNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBD0</accession>
    <name>A0AAV4SBD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_111461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009277">
        <property type="protein sequence ID" value="GIY30787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10967" checksum="038A0DD3564C3CAA" modified="2024-11-27" version="1">MKKRMESTEDTHMIRHPSQTAGGALPPIIAAGGWGWGMKQNLPSSSGGVRVAEEDYSCFKRRWGIKWASEYGFPATHLHRNKVCLFKRNKTAISFTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHK2</accession>
    <name>A0AAV4SHK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_227911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009412">
        <property type="protein sequence ID" value="GIY31682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14637" checksum="E8B368E44A07C5E9" modified="2024-11-27" version="1">MHNNSVGWRVYDSLSTLRLESLIFLRVENSRRARTAERTKRVCFGRQQSSWGNHAASVSERTSLLLCFSAHTLTGFVTKISCSSFRFSTLDCRRRFGGLMSLAATRWRQDLCEWSIWLKNNIDRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNH6</accession>
    <name>A0AAV4SNH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_548871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009823">
        <property type="protein sequence ID" value="GIY34874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY34874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="13928" checksum="53CFD69F07C775AE" modified="2024-11-27" version="1">MNRSELTSETLTGPLLCSLDIPGNRCPPRLANPAFPFPNPNPHTPSPESSSIPIKSIPHHLTRTHRFPASSLTTQAQPPKLHLFPTPSKFMNMITEYTKQRPSLDGNSDYAGVLERSGRSTPSERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXX2</accession>
    <name>A0AAV4SXX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_234563_1</name>
        <name evidence="2" type="ORF">CEXT_674811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010443">
        <property type="protein sequence ID" value="GIY39308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57277">
        <property type="entry name" value="Granulin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043786303" evidence="1">
        <location>
            <begin position="23"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="351" mass="39101" checksum="FE95564E566238C6" modified="2024-11-27" version="1">MNSIGMSFTVVLFLLGLASVRPQVFSPNGLPSENQFLLSAMENGVDITQPENTMMGQNLKEMGVEICPDKLHLCPATADCCKKDDVKWDCCPKTTADAPHTISGECCHHLGFKWTCCAPSVPKCHWFGCWWNTISKPLREDDQQCLLPNQLDHWNKGTCTSTHNLNVFLYGYGDEEADLLDENVFYSCSVFGGTWISASSSIFQMGFLLENQFSLSAMKSRVDITQPENIMMGQNLKEMGVEICPDKLHLCPATTDCCKTDVGKWDCCPKTTADAPHTISGECCHHLGFKWTCCAASVPKCHWFGCWWKFISQIEAANLLLKASSSESCLTYTTPGCLKKPSDKKSWKMFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0Q5</accession>
    <name>A0AAV4T0Q5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_792901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010491">
        <property type="protein sequence ID" value="GIY39619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0Q5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16802" checksum="5D6AFE037F93188C" modified="2024-11-27" version="1">MDSAFHKREMRVLVSSLTCLQFYSSLGLFSKPLFWAGGGHKVAISTTDFLNFDNAVILSKSTTRWRFPVVRTCTSVAERKIFPLTDAGFGSSPSTLNPLLPPRNTPLKVGHAPKRNAGTDGILRMLQEVGNVVSQTVLESKLHTQKFQPIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2R6</accession>
    <name>A0AAV4T2R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_705151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010543">
        <property type="protein sequence ID" value="GIY40004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="8939" checksum="0E7BE3A9DF456910" modified="2024-11-27" version="1">MLFLALISESTMDLFRSISKKSLIFLPRTNPFVPSLFPKIGAITLGRKTVQGKGTVPTAAANSRPQLIDGYISADKLGNNSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9T9</accession>
    <name>A0AAV4T9T9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_340971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010652">
        <property type="protein sequence ID" value="GIY40728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9T9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="17583" checksum="829FE3EA9B5A4EB0" modified="2024-11-27" version="1">MNPATFTKGHQVMERGLQSLKRIHRVGLREADTNAVNRINASRQSLQKIYFPQNSLLRTNSNNRRLNHSTCKSGNVPRIFHKGAPCNEKGGLQKLGTKRINPVGPSGADTNAVNIEVDDYEGIFLSCCYESLKETSLLMAFYCSASSSRTSSLQYSSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TF29</accession>
    <name>A0AAV4TF29_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_615461</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011036">
        <property type="protein sequence ID" value="GIY43809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TF29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001557">
        <property type="entry name" value="Transcription factor E4F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051643">
        <property type="entry name" value="Transcr_Reg_ZincFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24396:SF19">
        <property type="entry name" value="FI01119P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24396">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="104"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY43809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15946" checksum="5CD1DD681355B9BD" modified="2024-11-27" version="1">MSLQVFRVCSTSIHYFKPKKDRCYICLEVFENYAALVDHIKIHTELLLTCPVCDKVFRQVDPATLHKNHLRVHTKETPYVCEKCNRGFSQVGNLKRHLALHVEKKINSEDDNSSDSNKEPPNKEPLNKEPPNKELFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TI30</accession>
    <name>A0AAV4TI30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_790081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011354">
        <property type="protein sequence ID" value="GIY46005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TI30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9741" checksum="8ECD592391497FFE" modified="2024-11-27" version="1">MFPSSSSKATFFPGDSLQRLPESAAVHRGHIPVRQLLPEYGLSGRGTLPATQCHNRDQDVLQHVHVQGQHGSQAYLSGCQEDGRNGDDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TT96</accession>
    <name>A0AAV4TT96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nrf-6_0</name>
        <name evidence="3" type="ORF">CEXT_557321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011694">
        <property type="protein sequence ID" value="GIY48271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TT96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006621">
        <property type="entry name" value="Nose-resist-to-fluoxetine_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20146">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043641002" evidence="1">
        <location>
            <begin position="24"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Nose resistant-to-fluoxetine protein N-terminal" evidence="2">
        <location>
            <begin position="84"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY48271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18299" checksum="ED7B00F0162F37B3" modified="2024-11-27" version="1">MNFSKIGVPLVLFFVLCLHFSRASSNSSSSVSEQDYDAQVEEVIEKWRENFRRFRKMTGTAIKMAMPHFMDSVTSDEFMVSNKCKHALFQWIADLRSMKPHALRMADASAKMINGILTGTLASFGSYDQCVETVVPNKDVRGQYCTIEAWPPLPRSRGFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUK4</accession>
    <name>A0AAV4TUK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_152801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011729">
        <property type="protein sequence ID" value="GIY48590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11195" checksum="BF6ABE04B42D45AB" modified="2024-11-27" version="1">MEKHRSAIRSNGFSNAIRRKVTFRHRFQGQKEGEVKNAKGGGDLQVRKPSRQLMFPEKLDEINYKSSEQKRKRSIAFHPKERCVVVEKIQRNGNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1T2</accession>
    <name>A0AAV4U1T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein Luc7-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LUC7L</name>
        <name evidence="4" type="ORF">CEXT_427991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012140">
        <property type="protein sequence ID" value="GIY51669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY51669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="341" mass="40078" checksum="F1D312C86BA10DEB" modified="2024-11-27" version="1">MSAHEQMRAMLDQLMGTGRDGENNKFKVHFTDPRVCKSFLLGCCPHDILAATRMDLGECPKLHDLALRADYESAAQKKDYFYDVDAMEHLQNFINECDRRTEQAKRRLAETQEELSAEVAAKLQRVHELAEQIGKQLALAEKLGAEGNVEESMKTWEEVEELRKQKAVAEQEYRNSMPASSYQQQKLRVCEVCSAYLGIHDNDRRLADHFGGKLHLGFIAIRDKLKELKKGRLERDRDYLRAREERNKTDRSRRHRSRSNSRHRHRSRSDERKRRSKHRRRSSSRERRRTHRRDRSKDRSDKTKVADLIKILVCHFRSRSAERRHSHSAPSNDKEVTNHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4P6</accession>
    <name>A0AAV4U4P6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_574701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012278">
        <property type="protein sequence ID" value="GIY52700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4P6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15919" checksum="FD0621AE3B263FC8" modified="2024-11-27" version="1">MGMCRHLRKNKHNFIKILQRSCILRQKWIMEIQITIQQNKTGIVCYPIRIFQRAKRQGNIPLVQASEFNSNNMEGCNIREVDNCGQERTDQDRRQPIKLGKFFFFFSRTPVGYRFLCSIFAPLPPLWEVQRGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAW1</accession>
    <name>A0AAV4UAW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Insulin-like growth factor-binding protein complex acid labile subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">X975_23536</name>
        <name evidence="13" type="ORF">CEXT_184071</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012573">
        <property type="protein sequence ID" value="GIY54918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051432">
        <property type="entry name" value="KCNMA1_auxiliary"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46473">
        <property type="entry name" value="GH08155P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46473:SF23">
        <property type="entry name" value="GH08155P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY54918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="375" mass="42920" checksum="CBADB7862674BD7A" modified="2024-11-27" version="1">MGFAGTVYGVYDVNKSEINTSETTQRRDPFAIVNGLRSANYSQNSTEETALHPIYTDYVAAFKSPTHTYWKHLLQLTSKEYLFSNLFSNFSSKKKADSMTVQKIKRSLPEEISFESQLLKMFFALPMFKDPLNKHRIITILRIAFEGLRNLIHLDLSANNIESFTEDVFVFTPKLKSLNLSRNSIILLSSITTAVSHLKYFENLTLDHNINIETILKSDIQSLKDTRLKSFSLINSSLENIENEAFTRLFFLNVLDLSVSYMNNEALSNVTSGLEYLSIKYFGVQSLVNLNNFPKESLVSLRDSSIYRLDLSTNYFPEITEFPYIPSLRSLWLTRCSIENIETGAFAKLLNLVELDLSKNKLFMHPLGTTVLKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULI0</accession>
    <name>A0AAV4ULI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Claudin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_36841</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013091">
        <property type="protein sequence ID" value="GIY58705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004031">
        <property type="entry name" value="PMP22/EMP/MP20/Claudin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21215">
        <property type="entry name" value="LD36024P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21215:SF0">
        <property type="entry name" value="LD36024P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13903">
        <property type="entry name" value="Claudin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043528704" evidence="6">
        <location>
            <begin position="19"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY58705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="277" mass="31928" checksum="926BBB9C2E114172" modified="2024-11-27" version="1">MACSAVTLSFATITAVVAVACLAIAFGTDNWYEIRVNRTIIEEREPTQSQKEFDEDIRYFSRDVGLFRMCFPDAEKPKKAPLYMSPVQTECLNLDYYIPQNQENENTKRFTDQRWERIHMARSVIGMYIVGFFFIFLSFFTGVAGCWKRSKGNILATGLLQMLAALVDAGAMGLWHGVHYYDYQKLTDEMSYYNWPDFFYGWSYILAWIGVGMCLLTAILFLGAACCVVHEKKLEQAKNMQYLMPVYPDKRQPYGYGYAYPGPYYTHGSQYGGPYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UP95</accession>
    <name>A0AAV4UP95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_89771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013214">
        <property type="protein sequence ID" value="GIY59540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UP95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8356" checksum="60FAAB43D7A077AC" modified="2024-11-27" version="1">MINKRGREIVAREQERNFYDYPSLLPPSSPNVAIGKEHRFSIVTGSGDLFYRFCNSLMCPFGGRLFSLINVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URT7</accession>
    <name>A0AAV4URT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_45141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013332">
        <property type="protein sequence ID" value="GIY60492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11263" checksum="6B7242DA405635F8" modified="2024-11-27" version="1">MATDNQCIVEDTGPFEIAPCSRQMFWWGRQIHSKRSEMTLEVFLEEYNLKTADPLSSANTESIRALGWWSTKRIVSNVPTKAKHLKPGFEACGTKGQSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY24</accession>
    <name>A0AAV4UY24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Down syndrome cell adhesion molecule</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Dscam_12</name>
        <name evidence="10" type="ORF">CEXT_632251</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013645">
        <property type="protein sequence ID" value="GIY62653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056754">
        <property type="entry name" value="DSCAM/DSCAML_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25059">
        <property type="entry name" value="FN3_DSCAM-DSCAML_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="9">
        <location>
            <begin position="168"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY62653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="29743" checksum="C1BC1A5EB5435B75" modified="2024-11-27" version="1">MMTGHSKHTYPPVSPNLTIVSATTSSIQLKWPPPEKDSNPIADCIAAFTPSYPYQSFIRLHFCLQSMFYLSIAHQSVLLSSQFSHQTRMIDDWQISCPVYATICSDIICTSRRNMRHGKRDKYPDIRQLTYFKTCTVVPIISFYIVAYNAVGKGKPSEVIAGKTAGTAPNPPKRDALLSLNSTVVSLHLNTWLGGACPVNFFIVQYKANIQREWILVSNNIVPEQKLLTITDLTPGTWYTILMTAHSEAGPTEAEYVFATLTAFGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZQ7</accession>
    <name>A0AAV4UZQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PDEase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_87638_1</name>
        <name evidence="4" type="ORF">CEXT_348951</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013741">
        <property type="protein sequence ID" value="GIY63442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY63442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11598" checksum="BF50FF03D9BBDE35" modified="2024-11-27" version="1">MMMACDLCGSWKRWEEHKNIVWSLYKEYFNQGDKEVNFGMVTPGHMLRTNAESIPRYQTAFLINVAIPIFELLSKVFPQLSEITKTTQENLECWKTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3H2</accession>
    <name>A0AAV4V3H2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_261784_1</name>
        <name evidence="2" type="ORF">CEXT_420531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013924">
        <property type="protein sequence ID" value="GIY64792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3H2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="311" mass="35672" checksum="32143BF7A0CED4D4" modified="2024-11-27" version="1">MPSIPFFAALLSKQDMASWTKFIPRKPRIHKAFRAFKSSAKNIKHLQTAVTGNKKLRKVVSGLFSKKGVTLAASATVLDQDNQKNVCNGFDEDVEQTCCRMCDCQFTNCLPNQTMECRRPSVGEALSHFSQSLTSNVWSFLGALMPWIYWVGCVLTGLLALFLAWKPNLFKAFDFSVTLELVQNETVKKAAKTYIYRLLAEKEKFGYLYFLLNQRMAVPLDVQFNGELVIESENFDQVVETIEKMAQEFNCNTKIFEVTCVELLYFFTMLVNPYVKWIAVDYVLQCARTHAYLISAPDRMVKMPPTLENYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3R4</accession>
    <name>A0AAV4V3R4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CARD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_179890_1</name>
        <name evidence="4" type="ORF">CEXT_65431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013892">
        <property type="protein sequence ID" value="GIY64544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3R4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042157">
        <property type="term" value="P:lipoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042981">
        <property type="term" value="P:regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1230">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000074">
        <property type="entry name" value="ApoA_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001315">
        <property type="entry name" value="CARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005539">
        <property type="entry name" value="ELK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003611">
        <property type="entry name" value="NUMOD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372">
        <property type="entry name" value="DAUER UP-REGULATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372:SF11">
        <property type="entry name" value="RE19971P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01442">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01188">
        <property type="entry name" value="ELK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00496">
        <property type="entry name" value="IENR2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50209">
        <property type="entry name" value="CARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043764046" description="CARD domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="CARD" evidence="3">
        <location>
            <begin position="318"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="140"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="424"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="632"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="719"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="795"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY64544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1052" mass="123936" checksum="B3C7FBCC531ED958" modified="2024-11-27" version="1">MKFLAVLFLAGLALASAIPLPSYDNAVDEKNFALEDFYLDLALEADETSLDDLKAKLKERFQEILEKVKDAIEQGKVVKGDYLEKLKEIREKLRDLKVDLSGKAKELLEKLKDKAKDYWKKILDKLNPDREDVLYADDSLDELKNKLKERYQEILEKLKEAIENGKVVKEDTIEKLKELREKLREMKVDLGEKAKELLEKLKEKAKDYWKKILDKLNPDKRSVEEELYADDSLEELKNKLKERYQDLLEKLKDAIEKGKDVKEDSLEKLKELREKLKEMKVDLGEKVKELLENLKEKAKDYWKKILDKLNPDKRSVEEELYADDSLEELKNKLKERYQEILEKLKEAIENGKVVKEDTIEKLKELREKLREMKVDLGEKARELLEKLKEKAKDYWKKILDKLNPEKRSLVEELSADEDIKTELGKKLKERFDEILEKVKEAIENGKTVKEDYLDKLKEIREQLKDLKVDLSNKAKEVLNNLKDKAKDYWNKLLEKLRPEKRSAFEYEFADEDPKTELGKKLKEHLDDLLTKLKDAIEHGKTVKEDTLEKVKEIRQKLKDLKVDIGERAKELLKQLKEKAKDYWQKILDKLTGKERRAAADDPSTELGQKLKEHLDDILTKLKDAIENGKVVKEDTIEKLKEIRQKLKDLKVDIGEKARELLKQLKEKAKDYWKKILDKLTGKERRAAADDDVKGEIEKTLKEALDHILERIKGAIDNGKAVKEDTLNKLREIREKLRDLKVDIGEKAKELLEKIKDRAKDYWKRILEKLGLEKRAIDFHLEAAFADDDEPKTELGRKLKEHVDEILEKIKEALEKGKGIKEETLEKLKELREKMKEARIDLGHKAKELVQRIRDIGKEYFQKLLDRLGLHKRDVDEIYEADFNLFEVFNKLKKFLKEKFDADQLKEKVESLFGKGSEVAEQIINMLKNKGEKGKNRLLDWIDRILGQNESKRSIADVYEKIKNYFKDLNIDLKEKFTKFGEWAKSQYEKGLEKGKDKLDNIKKIANQFLEDSKKISKDVAEEALEFFREYKKDLGKVFDDIKEKTKNILKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7E3</accession>
    <name>A0AAV4V7E3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_152309_1</name>
        <name evidence="6" type="ORF">CEXT_337181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014037">
        <property type="protein sequence ID" value="GIY65849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015889">
        <property type="term" value="P:cobalamin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002157">
        <property type="entry name" value="Cbl-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051588">
        <property type="entry name" value="Cobalamin_Transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559:SF18">
        <property type="entry name" value="TRANSCOBALAMIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559">
        <property type="entry name" value="TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01122">
        <property type="entry name" value="Cobalamin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="408"/>
            <end position="410"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602157-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602157-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY65849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="460" mass="52668" checksum="B9FFE2C12751DAC4" modified="2024-11-27" version="1">MLRTHYLRELIMLIERTTRTQNSLPKNSFIQEVFTVLYEREDDKISLKASYLRKKKSLVVNWTYELRNDENPTRKWGSEVARIAVALYLSNNTVFTKDTTLREEIAYELSLDLLSKLALKKIEDVSSTELAAYINAFLVACINPKKFYVLDLVSELRRRVDAQNYTNPSVLLALCNAGDRITERDVQKLLSLFFKAHREFWTDTEALAILALTCAAKQSYDVYHMEEINKLTNELKTRQYRNGTVENMKTTALVMQALFATQSEADEENFDEEKALKQILHSQLADGSFGSIVNTYYVLPLLSGQSLVNISSSHCKPAVVDDKDAIKDLMNQVGEKWRIQISLWIGNNRTVERTLALKVPANTSLYRVMELAAVIDNKFKFEYSMRNGKPFIYSISELQDDPENGMFWFLFTSKDELKEQLQPTAKVQLILFQGTISTQCSGTSVAHGTCEPWSYKSAPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAB0</accession>
    <name>A0AAV4VAB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_482981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014195">
        <property type="protein sequence ID" value="GIY67062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8643" checksum="13B3B8D1E1648707" modified="2024-11-27" version="1">MRMEIKETLNLPDKACSDFIYGHVNRDVSLSNRRQKTLKMKLFEFLHLSTIPSFQFTLTQLFNKFFFFYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCT8</accession>
    <name>A0AAV4VCT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_288801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014227">
        <property type="protein sequence ID" value="GIY67320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7583" checksum="C73DB7CA4A50EF56" modified="2024-11-27" version="1">MATVPPWINIKKVSHVSDPYTETLRPGAPMTSQREGPTGEGHHYQYVGPYRIEKTLGKGQTDSKEIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFZ2</accession>
    <name>A0AAV4VFZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_607071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014503">
        <property type="protein sequence ID" value="GIY69205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8187" checksum="1EA607A12830003A" modified="2024-11-27" version="1">MHWCSHSSRCSTGCLGECILRGGGDAREGARGHRSSFDCRYACATGGCGNRDAGHSPPRSSCSWMIPAPVDEKMVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VIF4</accession>
    <name>A0AAV4VIF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_74051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014527">
        <property type="protein sequence ID" value="GIY69394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VIF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9546" checksum="E90B5ADB56CA41C6" modified="2024-11-27" version="1">MRDKCENRVFGPHEGRCILMDANDVNAKRRKKTLKVTVRHKSHRFQSKNTNFEKKISRFQCLIVGVIQFWRHSRRYVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VYC6</accession>
    <name>A0AAV4VYC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_746081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015222">
        <property type="protein sequence ID" value="GIY74463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VYC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8738" checksum="107670D691561D18" modified="2024-11-27" version="1">MERNSWRLKGQTPRTKPVPEKVRLSFSGTDSMWVKSIRSTSCFCKRVHVFYCSEMFICDELKLFTYSLNDIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0E3</accession>
    <name>A0AAV4W0E3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pgam5_1</name>
        <name evidence="2" type="ORF">CEXT_811081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015375">
        <property type="protein sequence ID" value="GIY75669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051021">
        <property type="entry name" value="Mito_Ser/Thr_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13750" checksum="0D5FD58708E48E8B" modified="2024-11-27" version="1">MNKNIFSWSSKWLIAVSGSSALVGVLHYFKSDEKECEASTKAYIHPSVKWDHNWDRREISSLVKPSKSESDSFEQNKINEQKSKLIPTATRHIFLVRHGQYEDWKNEDKDRKLTPLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9E6</accession>
    <name>A0AAV4W9E6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_76021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015899">
        <property type="protein sequence ID" value="GIY79525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9E6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043786335" evidence="2">
        <location>
            <begin position="19"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY79525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16168" checksum="F06DAACB1226C469" modified="2024-11-27" version="1">MIPVKALFLLAVVVITSCSTVPEQTSSQSPADPSTANPVSVDSGETTRKPHTHEEHPVDDPDHTDHPGHENDAAPSIKPKHHEGDHDHSTDDKVDDGHDHSQHDQEIKDQEEKVKPTKVEEVKDTDNDTQESRFKRGLWRRRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9W4</accession>
    <name>A0AAV4W9W4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_705371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015922">
        <property type="protein sequence ID" value="GIY79705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9W4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="19090" checksum="DD3C7AC71396AC21" modified="2024-11-27" version="1">MDVCSGSESTLNRRDDKTAREPLDGLRLIMGCNARELSLDGQSTRPSRCSTLTQNVHPQQKPALSSQKAVVLISGGGSNGGMKTEGGGPHDGCVAGLNGWSLNTASRWSADTRVGVPWWITLWSSKHSKPSCQIRILTNHAKEAESEACVSTVEISSVGLKIFMFGVGREAEHPNAASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9Z9</accession>
    <name>A0AAV4W9Z9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_126580_1</name>
        <name evidence="1" type="ORF">CEXT_388541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015844">
        <property type="protein sequence ID" value="GIY79078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9Z9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15554" checksum="00D8E0475D129B91" modified="2024-11-27" version="1">MQTLRFFSAAMNGVHTKNWVYPNNIRLSYNPQGNGLVELLNKTLIDTLSHLVSEKQEDWCQHVPLALMAFKCTSPFNPGNAGFSRFMVEICKCLMILYFVIRLGRTLIRLLLQLNWLIGFSLLFRLSKTTSRKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WA81</accession>
    <name>A0AAV4WA81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_806841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015884">
        <property type="protein sequence ID" value="GIY79406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WA81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9577" checksum="98D36909D5EC831D" modified="2024-11-27" version="1">MINRKFTRNATEEYKQTRSNERDYTKSKKKCHKENLLEEVERLKSFNESRAFYRAVNKEHKDFKPKRPPSVKRKTEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRB7</accession>
    <name>A0AAV4WRB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nrf-6</name>
        <name evidence="4" type="ORF">CEXT_111381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016632">
        <property type="protein sequence ID" value="GIY85242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006621">
        <property type="entry name" value="Nose-resist-to-fluoxetine_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF0">
        <property type="entry name" value="O-ACYLTRANSFERASE LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20146">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00703">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="509"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="572"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="631"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="Nose resistant-to-fluoxetine protein N-terminal" evidence="3">
        <location>
            <begin position="16"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY85242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="741" mass="84322" checksum="C8CDCA28243CDF2C" modified="2024-11-27" version="1">MALPYLMTIVTETRLSGKCLSGLLMVVKGVMDIKSWAVRLLDALGKPSAGLLEGTATALGDYDECLDITVPRRMRPVPVPPYTEKQIAFHGQFCVVEIGLPKAIKQAAMAYQIGNRSSSELANSKTKEEDLESWTLSFKEKRHILHRSTTQTGSFEGFGANSSKGRRCRVPYGRMHSFSLHQNDLQLIINEVSKLILLDANTIRCETKQKANFEVQQILILCVYGIIGLLIFFGTSLDVLLQFTKTETIDDFYLRKQNMWIQSAMAFSIPRNTQKLLSLTTNDNSKIASVRGMKFLTILLYIIVWTYASPNDYHFFKFRSAFYFFKFLEQIWFSIFANGAMGIDTLFLIAGLHISYQFWRKSVYQRIAVNAHKFLLKWYSRFALSQLLIISLVLCLPLIGSGPIWADIVTPEVENCKKRWWLNILALNNFWSSDDTCLVHTWLVCCLFHMFIIAPILLFILSRSTTVGIFVNCIIIMGSSVAIAMITLMNDLPPSLTFYLMSFANIKTLWQKIFIQAYSHIAPFCIGILLGFFITRYDKMQLRKTTVLLGWFGCHCIELNSVVIVWALTISWMIFACTYGYGGFVNSILSSKFLIPCDRIAVLVYVLHPLILFIHEGQLRENMFMGHLDQLMHGTACVVITIVFAAICYITCAAPFEFFEKKVWYEPPPSYEAEDAENPKCKGKSNKGCESTDMCKQQPSTSTAGDSEHPKLKIKECIIDTIQSQKKKLNYFRQSLNITSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTF5</accession>
    <name>A0AAV4WTF5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_798391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016691">
        <property type="protein sequence ID" value="GIY85787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTF5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001119">
        <property type="entry name" value="zinc finger protein 408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000038">
        <property type="entry name" value="Zinc finger protein 624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF142">
        <property type="entry name" value="ZINC FINGER PROTEIN 384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY85787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12507" checksum="ED67F4B888682B57" modified="2024-11-27" version="1">MNALISVPNCTNTFAIFTVVKIRINVRNVTNTFAHPSSLGRHFRSIHTAEKPYKCTECGQCFPRRDTLRKHIRSIHIVEKPYICMECGQCFSRSDRMREHVRGMHTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0A2</accession>
    <name>A0AAV4X0A2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_579821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016932">
        <property type="protein sequence ID" value="GIY87375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043752816" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8606" checksum="B4B92A1E092A4C96" modified="2024-11-27" version="1">MVLISTSLLASYMLGIKAAATGAGQKSQVTFSSRLFRQLRTTSSRARRRFSRPPCSPAPCTSRQSLAFILFHAKGSLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1Z1</accession>
    <name>A0AAV4X1Z1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_642991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017016">
        <property type="protein sequence ID" value="GIY88049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1Z1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10052" checksum="C9C16873B8C04D26" modified="2024-11-27" version="1">MRNSTHISCLTVGWSSSARPLIFRLFIVTKIRVLHIAYQMEHHFISTILPVPLCKACMRIRRRNAAVCSASVHGREASFFAGHVMSILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9X1</accession>
    <name>A0AAV4X9X1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_527942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017448">
        <property type="protein sequence ID" value="GIY91706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9X1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="221" mass="24896" checksum="1FA6FED00CB67E78" modified="2024-11-27" version="1">MIILGERRRRTRASFRVESQIIPRSNNMSSPFSNNTPANGYVDFMDYGNAIQPEFRNTGPDYNPYTSQYALSYQAYNTSQLNIPSNLTPPQPDRTSPYDMSYYAGTPRYGHMANTPLMQYSYDASYYNNFSQQSQMMPCRPDMNNSGTFIQTGDFGNKMNSPSFTPPTTNFDTVPATIVPQTPPENSTSPSGVSTSPVVDQTTVPNLTKDMYPWMRTHSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHY3</accession>
    <name>A0AAV4XHY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_239921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017822">
        <property type="protein sequence ID" value="GIY94777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13806" checksum="9C0B00253477200E" modified="2024-11-27" version="1">MRLGRSSVVLSKLIPRHVLFQGEEFPSQCLYLHDKGRVPTVLSSNRKEFTLVYLSSLGRQDRVPDYIPENLWPAWQIEVCTRINRFAFFRQKFRRVVETHSGARTIPGRKVPFAVSAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJV9</accession>
    <name>A0AAV4XJV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_257851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017813">
        <property type="protein sequence ID" value="GIY94688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="295" mass="33371" checksum="B430D9EEBA4235CA" modified="2024-11-27" version="1">MDEQWSKRSIDLSLRRPKSDDNCDNPICFSLSSNLICVILNLFVLVMVIVYPPSSNCYFSTVQISRESYGTRQVYFTTWTKSVMGSVIVPMILGMFAESWGRISTLVDHLFMSCYPWIVSSACCKYSASLLTTWTKSVMGKRHSTYDSWIVSSACCKYSASLLTTWTKSVMGKRHSTYDSWIVFSACCKYWQVYLQHGQNLLWGSVIVPMILGMFAESWGRISTLVDHLFMSCYPWIVSSACCRYSASLLTTWTKSVMGSVIVPMILGMFAESWEGSQLLWTICLCPAIPGIFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKE6</accession>
    <name>A0AAV4XKE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_169691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000413">
        <property type="protein sequence ID" value="GIY94670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16630" checksum="A6D749AC06DFC3AE" modified="2024-11-27" version="1">MLETQLAVAHDWNGTAKNVAQGHCQMRQYLTDMLTQQRKKLSSLGSCSLINCPKHAINNNVKPKRNSNHLTSNNLSIDGFQYPNKKLTAKTSYNANGNDNNLKLKNKFQNLSNVNDVDENSDINVTTIKMPPIMVKSMENLTLTLKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL69</accession>
    <name>A0AAV4XL69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_105963_1</name>
        <name evidence="8" type="ORF">CEXT_225211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PIERCE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017820">
        <property type="protein sequence ID" value="GIY94769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026507">
        <property type="entry name" value="PIRC1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20899">
        <property type="entry name" value="PIERCE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20899:SF1">
        <property type="entry name" value="PIERCER OF MICROTUBULE WALL 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14892">
        <property type="entry name" value="PIRC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY94769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10921" checksum="7079D067527489F1" modified="2024-11-27" version="1">MPEMDSERPCTRYEDQDMRTSDAYKTNNLPFRFDHPSKWNYGNCVFNASDGPPCIHTMPLTYHTRNHKYWEHLSSVGMYRNRGFNTAIDRAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQI2</accession>
    <name>A0AAV4XQI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_280171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018148">
        <property type="protein sequence ID" value="GIY97301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="15212" checksum="9E5DD06C312F7DDB" modified="2024-11-27" version="1">MLSYVRRFYPRHFSPLPCLPLPGDGRDLKREEGHSKLIFKQMLQFPKRLLEVLEIDTSIKRNDQRLFQTKSGMMTFVWRRHLCYILVMVMCERSLTEKCDAFFLLRRFSIADKRKSKPRLSSIKNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT92</accession>
    <name>A0AAV4XT92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018283">
        <property type="protein sequence ID" value="GIY98376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12695" checksum="3CD07E142EA24C95" modified="2024-11-27" version="1">MLNAVVMNLGEGEGLAFFPDGSFFLLFKIFSGKGRNGRGSLSEHGIIQVCLIELIKLFYCVSPFGQMRPAISSRNHLMIRLRFFAFAVSEIIPFGYKQLVLQPPEKFMYLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XW70</accession>
    <name>A0AAV4XW70_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_493341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018270">
        <property type="protein sequence ID" value="GIY98219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XW70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11432" checksum="08B2EEEEC2362FF3" modified="2024-11-27" version="1">MRNAVDNKKGFGFVTFADPDSVDKVLANGPHELDDVNLNSSAFNKSEIFHAAQCKHKMRSAPCSRISSIVNRPYSHHSPAVTAKQGGCSTLHHKGFTGAAPDLGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX39</accession>
    <name>A0AAV4XX39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_197301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018435">
        <property type="protein sequence ID" value="GIY99567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="27746" checksum="2498C5859B8CB962" modified="2024-11-27" version="1">MFQLRGNGPSEGRLEVPSPPAVESQEKPVEKVSPEEMCRQMSTALKEIEVIDSIVESSKRSDLQQDYVQITETLLQKRKFLEEWVSRYHCPIDNCKLHKISKTIVNCNVNNVVNCNSSKSVTASISSNVNKPVVHSKSVTFVNASNSGKVNGNIKSKTKRNASQISSNANDSGEFRTPNKKLTAKANFTFNKVSVSDDLVTKNNFQALSTDAAAEDEGSIKETLKGLDKSIECAINDDELEEEIEGSLRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXE3</accession>
    <name>A0AAV4XXE3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chloride channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ClC-a_5</name>
        <name evidence="1" type="ORF">CEXT_223461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000930">
        <property type="protein sequence ID" value="GIY98463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10104" checksum="FBE0F1417E0335B3" modified="2024-11-27" version="1">MTDGTERAAMGYEHTLMFGQYREDLGEYARLEATRLKSLEKHRKKEEKRRQKELKPYKNAIHRKLVGLWQNTFARLGKTGFSLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXX5</accession>
    <name>A0AAV4XXX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_548891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018441">
        <property type="protein sequence ID" value="GIY99617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11761" checksum="226D46C73B49467D" modified="2024-11-27" version="1">MLSLTRPFKSMQFKPNGLTVPFQEHSIFSRYEGLPSSALLRFFCSQKDSGKMAYRAQTTFPSLIYPADDIHSRVPVSRQRKCQFQRAEENSCKSPTKEHSGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY53</accession>
    <name>A0AAV4XY53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_305801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001112">
        <property type="protein sequence ID" value="GIZ00057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="10874" checksum="D2213E2917D577D3" modified="2024-11-27" version="1">MPSRILHSLLSPEIDLGVSGIDIRFTFVSYTSSSFRSTAALSACSCPEIFESLEAPPVSDQQRARVKSTCFGITSMNIAPNGDPTRLLPGASMTAPLMPPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYV4</accession>
    <name>A0AAV4XYV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_41451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001051">
        <property type="protein sequence ID" value="GIY99488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14407" checksum="FEE4E8526EC7016E" modified="2024-11-27" version="1">MLRLKVSVISPSLRVLYNVTWLTTEMELINENLATCIYPVSENEGSTTNLFSHVKLNNPIEHNVSIIKTTKTVSYNHEETENSSVGDEICSDKINSAAFKEKPKILLVFQSISSSIEKQCTTILLKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ44</accession>
    <name>A0AAV4XZ44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_583441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001005">
        <property type="protein sequence ID" value="GIY99108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10092" checksum="EFB5F6B77C8A1B0E" modified="2024-11-27" version="1">MDRFSCQRPFRLLRYQPSLPTSRGNSLLVYFIHIKRKWTNCFIVKIELADGIIDLFTEPERYTEVKIGCYVASRAFVSKVVMSKGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1M6</accession>
    <name>A0AAV4Y1M6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_406281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018490">
        <property type="protein sequence ID" value="GIZ00040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1M6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7664" checksum="0A7E18C6DAF27B16" modified="2024-11-27" version="1">MICPGKWLNTIPIYVIDPENRARFFRYRFPDFGKGQLGVGFMTICKRQTIILVNMPMLQILCPTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3S0</accession>
    <name>A0AAV4Y3S0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_742391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001209">
        <property type="protein sequence ID" value="GIZ00804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3S0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="19090" checksum="D7634A1CE5EAA05A" modified="2024-11-27" version="1">MVRQERSFQCHVLFQIACCDAMGSSSQHYRDTAPAPTEDWENVTAHATVTEGTARTGSARRPVARLGAGCVGAALGVGPARVRDGQPVLCAERALPAHRPAPQLPAVRAAPPLLAQHLPGRPRLLQARGALRRPPTDPRRPSHSAATGSVGPGLSLPSVSVRCSTLLRSYDSGQDDQNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5I2</accession>
    <name>A0AAV4Y5I2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4793 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_11673</name>
        <name evidence="4" type="ORF">CEXT_132251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018818">
        <property type="protein sequence ID" value="GIZ02502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5I2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032010">
        <property type="entry name" value="APD1-4_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39077">
        <property type="entry name" value="DUF4793 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39077:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE APD1-4 MIDDLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16041">
        <property type="entry name" value="APD1-4_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase APD1-4 middle" evidence="3">
        <location>
            <begin position="209"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ02502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="405" mass="44883" checksum="027AF2AD23B6F308" modified="2024-11-27" version="1">MIELVTCICFQRDGRAEDLGVVHPVRGVHRGRLRAVLHLHRAQDVAGAKDGAVRGRHEAGAAFLHPLVRSHSPHFRSPLRCIPGELTVTDRAETPEQAKGESEPETERRQKGQLREAQVLPLPGSVVEIFACATQFGARVLVFKQECECDESDSEEESLEDESEESDCTGDKIWSSNLCSSVISNQEIPSTGAGDDSSDCNEALGVKPIHVNITTSDFYVIAILNTNRHKSNEIGLHIALDRSRYTIQKSGHSFDMCSLSTSCTIGLSFASSDRALIWIPDEPNAGRSTFVVRSQCKPRLAVFAILSVFFPLMVFLGVAFVVRADRERIMRIYNCRSRLECEQECSDTRFVIPLLDNGVAICSDFTLYPPEETPDTPTEEQPPAYNTLFDPPPPYACVKEETTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9Q4</accession>
    <name>A0AAV4Y9Q4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_524781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001558">
        <property type="protein sequence ID" value="GIZ03146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17966" checksum="B5509D7DB6BE3650" modified="2024-11-27" version="1">MPEINIEDRWFSLHLELPYWMEENRKEFRKNLVPRLLFGGIMTHYAINIRERLNFRTYNCICLASFIQYGLIKPSYQSHWTLYTYFNAMLYTGALAVGSAASFIGWGRKFLVTRRLRDFFMSFLYFGSALYVDYIFRNPPIWFHLPDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAU6</accession>
    <name>A0AAV4YAU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_125001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018935">
        <property type="protein sequence ID" value="GIZ03340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11141" checksum="15EBF6BD27B1EAB2" modified="2024-11-27" version="1">MKFMSMDIVRDILSNSERPNEVQPKIKGDMIHGMERQIFEDGYPLRLILRPQQIPLKIALPYSTHPNKTLTHRTNFLAGPAVYWQWPRSPLLSAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDF1</accession>
    <name>A0AAV4YDF1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_789771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019194">
        <property type="protein sequence ID" value="GIZ05033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11448" checksum="301A3F150DF29CC4" modified="2024-11-27" version="1">MSVIQAKIFSATKANTFSTSRRLRNLTVAMEIVSKVASIEMMFGSRFVPVGAFGQKKNGYKKAVHGSSYPEGFTIFLERKNVLFTGSVTYLSPAKLFHSFLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M462</accession>
    <name>A0AAV4M462_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LIX1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LIX1L</name>
        <name evidence="1" type="ORF">CEXT_259711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001843">
        <property type="protein sequence ID" value="GIX67000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M462"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029270">
        <property type="entry name" value="LIX1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14954">
        <property type="entry name" value="LIX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16622" checksum="188FA0E3E4DFEAD1" modified="2024-11-27" version="1">MASDVSAADLPSVLANGSRACLSSTSTHLEGYQTILLKKLWEEAKSSFKLPTDTDDADKSHSGIDAFRFMLESNKGRTMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVVAHYSHRALDDDDMRSQMALDWIARSRNHQESSPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5W3</accession>
    <name>A0AAV4M5W3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_645551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001861">
        <property type="protein sequence ID" value="GIX67230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5W3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8094" checksum="5BECFDC286119A8C" modified="2024-11-27" version="1" fragment="single">AAARECLHTAELIQPAALLFRGMHPTPVINVRTPADGRILRKRSLSVCYKYRKSILCTIRYLLVKIQTENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7P1</accession>
    <name>A0AAV4M7P1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_512151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019463">
        <property type="protein sequence ID" value="GIX68132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13721" checksum="2CC0593423D7B982" modified="2024-11-27" version="1">MTNINPYPQNKKRNRFRRILPKNDTSLFAEVLYRLITRREKGKQGGWGRQEEGHDISSPRPNTTPFLVAPSDTAAVVHHLPQDRSSNFLPHPRDFKMNFCQRSPEFQTSLSKCEGGVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD37</accession>
    <name>A0AAV4MD37_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4757 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_132710_1</name>
        <name evidence="3" type="ORF">CEXT_462851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019631">
        <property type="protein sequence ID" value="GIX69934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031865">
        <property type="entry name" value="DUF4757"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15949">
        <property type="entry name" value="DUF4757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4757" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX69934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="26939" checksum="59D41E2E1B5C8056" modified="2024-11-27" version="1" fragment="single">NLDNWKSRRRKVSEKVIQRAEEMRQIEAEEQLRQEKYLQQQRKIKKFSEIVEKGQGNDSGLGGTPEPDDTIDSQSSLLRSDTSEGMTSEAESVDSDIHKSDKIHEKEPPKVPQKPQKQLKKDKLIEEFGDGQKSESIESNLCGQENYNGIKNGNIKENISSIRNQIQENNRKISEEMDYQFGGFLQTLSFSISIKPGDNRGFGFTLKGGKDQDVLHSSKISLNIAQLMLLDLKKVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MER3</accession>
    <name>A0AAV4MER3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_321621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002147">
        <property type="protein sequence ID" value="GIX70536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MER3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043427851" evidence="2">
        <location>
            <begin position="22"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX70536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14772" checksum="3A2E006AA321E8A2" modified="2024-11-27" version="1">MILIVVHYAGLSLITLYPTSCKTNFELMFPEMTCTICIPSLQNGIYFYKFMVTNFKINKIQFRQWSSGAAFSSKASSWQAAPSDSQTLFAGWNVDTGRGQEDVAGRSQGSLKSSTWERTCTLDTSQQKEKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMR0</accession>
    <name>A0AAV4MMR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_432901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002446">
        <property type="protein sequence ID" value="GIX73837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8943" checksum="FAE3CD20F34CE8BB" modified="2024-11-27" version="1">MLRGKRSSHSWQLPKKTASNRKQRPVRNRVACKTVEPLPFGKPEPRVKNQTLRRRPPGSRLRKTEEVFHSDAKLSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMZ6</accession>
    <name>A0AAV4MMZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_270852_1</name>
        <name evidence="2" type="ORF">CEXT_525251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002437">
        <property type="protein sequence ID" value="GIX73652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="329" mass="39028" checksum="BC3CEDBD3D0850C2" modified="2024-11-27" version="1">MDKDALMSERWNSEKLVETHEMLTAKDKICENLTSKIRELENELHILSETNNKLALNLNANEFKYKESIQNEKMKWNLLKKVGALKEENIFLKQQIQDLKISQTHSLEQISKLESASKQDQESFKEKFQGFEMICWSMKNSETKISLLESHKNDLEQELKEKSSQEIIRQQLEERIAMLEDANREQNDHLQRDLQVLYQLKTDITGLDLELSEQSHEILHLKKCLEEKDAEMKINEAKIKLEVKEKLDELEKSRRTFKMENNDKEELNSKTEIIQNLMEEIEQYQNKIKEMIKDEKNRTAQLQRAFEAYTKSYINNDPSGDKSHFKSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPS6</accession>
    <name>A0AAV4MPS6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002416">
        <property type="protein sequence ID" value="GIX73481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20214" checksum="68C8468473F3BC72" modified="2024-11-27" version="1">MLGVALDLNEEKFTFNARRIPDDVLSGISAVSAFCGAILPSLAQRKSPEIVCEGGFDELGSMRIRHRHVYCDVMGSGGLKMNGQRIVRDVGQWISVFFFNLENSVNHIVQGNVNEKAIGWKNIRCSKILKFLILDDGMIGLLDITLGCRTNSCFRCFTRNPASDVKSKTSSFIAGMGIFRCLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQM9</accession>
    <name>A0AAV4MQM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_776421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002521">
        <property type="protein sequence ID" value="GIX74678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="17750" checksum="B8C3A6B05E541290" modified="2024-11-27" version="1">MTRPSTFSTCGTLPAKGVQKRGWVGPERNSKMFRCECGEFFETERTKGVRGGTSEKCLQRGRVTDFGCKYAISQMLFRSVAAMDRARQTSPEFAYLSHPPPYLKLMTRSSTFSACGTLPARGGRKELKNFPMRMWRILRNGTNEGAGTGTLQKSVFEGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSM3</accession>
    <name>A0AAV4MSM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020165">
        <property type="protein sequence ID" value="GIX75385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10872" checksum="BE9351886008E18C" modified="2024-11-27" version="1">MMSRPRHLIFLDVGMYDSKCWEQTEDLSPVHSYREEKMALAEEFFHEYNVSSKRNSSGISNRWTNNPRSPSPANGLFGAISFLLYISCRHTAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MT40</accession>
    <name>A0AAV4MT40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Focal adhesion kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ptk2_0</name>
        <name evidence="3" type="ORF">CEXT_670831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020121">
        <property type="protein sequence ID" value="GIX74988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MT40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine-threonine/tyrosine-protein kinase catalytic" evidence="2">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX74988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8655" checksum="38B4F8CD65BA0F5F" modified="2024-11-27" version="1">MLKIVEEEGDYSTPIVKDYELKRTDVILGEIIGEGQFGDVHKGTYISKDGQTQSVAVKTCKVESEESMGESFWKKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZZ0</accession>
    <name>A0AAV4MZZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020385">
        <property type="protein sequence ID" value="GIX78092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11259" checksum="47E2ABBD8020992E" modified="2024-11-27" version="1">MFGKEPRKLLRKIPLTLKDGQILNYLSSTRHRRLIPFNSLVNPFVTTRPPLSSLSLSLSLLLSRERLCTCEEHISWIFSSKLETVFKKSRLKGAASLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N1W5</accession>
    <name>A0AAV4N1W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette sub-family C member 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Abcc9</name>
        <name evidence="11" type="ORF">CEXT_522741</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002779">
        <property type="protein sequence ID" value="GIX77651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N1W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF461">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C MEMBER SUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="297"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="501"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX77651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="697" mass="77987" checksum="291B7B5ECA510855" modified="2024-11-27" version="1">MLCLDPSIPNNWTLPIVSTKKECYVDSLSVLLNILLMLMTFVVILRYKCTKIEKKHGELVRYHEHCSRSVLTLCLVFLNLMEIGEGIIVNQFNSTSKLHIILTPVTSLLSTLSAILFYHYVERLNRPKLLLILFVFWPVAATLKLAKLVVLYGMGLNIYHMKITVTWAVTIVYSLLTAIDATLIIVQQAAEKSWSKNIPMEMLLANFLALIIFGGMMKISGDVVSLAGPLSISFILAYVTAVKEETLPHGTLEQLYYPTSWEFIQNGFVMTVIVLIATFLQSTLSNNFNHLAIAEGTHLRTALQDVSDERLKKTTELLQGIKLLKLYGWDRLYANFVQIVREKELKILRSDAICVAFNTFITQTSSIIVTLVTFSIFSKMEGRPLMPVDVFTGLALFNQLTVPLYIIPFVIPMVINAVVSTNRLVDFLMLPEVDLSLPWRDDSDAPDARVEFVPDSGSVLLHVKENSFDGSKGYLSGSEDGDGVFLPEFYNYPPVEENVLVSIKKGYFAYDSSYTIPSLRDINVQIPAGKLTIIVGNIGSGKSSLLSAILGELHVISGSINWNSSPLVAYVPQKPWLMNATLKENILFGQPYDGRRYHQGDSSIGGQKQRIALARAFYSPARLIILDDPLSALDAHVGAYVFEHGIKTLLLRRQRTVILVTHKLEFLSSATKVILMESGTIKKRGSSLKTLRLHFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6N7</accession>
    <name>A0AAV4N6N7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_413051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002997">
        <property type="protein sequence ID" value="GIX80093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6N7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11220" checksum="352B0AB0EF84DA46" modified="2024-11-27" version="1">MAQIKNEIDCNSFTITSLPLSEKPAFQPTLFQYHPFPFFFHLSPTALRRQMRRASPGVRCVEQWTDGPQTPRGYRVANARPPRAKKSVPLDDPLHLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9F2</accession>
    <name>A0AAV4N9F2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_456261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020679">
        <property type="protein sequence ID" value="GIX81445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9F2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="15092" checksum="372AE0C6EC824BE6" modified="2024-11-27" version="1">MGKKRDLWPLVKNYVHPETAVICTDKAGQYKKIDRLIKGVVHKTTNHSKGEFVDKNDTINPLEKENKHLKKAIVYRKCFGNIRLHTIPEEPGLIIWAKKKEFRGADMAVYPRCKRSLPWMPQIRPGNDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE09</accession>
    <name>A0AAV4NE09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_101671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003206">
        <property type="protein sequence ID" value="GIX82113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12554" checksum="61A0345524721846" modified="2024-11-27" version="1">MPRCKNAFEKNNLIIQFNVRTPEQVSVTAIEQIEAIFPPRLEYIIQDNADQVFCKQRAKIVILKPTPLIMAFTTILAVKTASELLGSFAFFIHLLPSFSPVGTLAQVASIGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIU4</accession>
    <name>A0AAV4NIU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_761531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003411">
        <property type="protein sequence ID" value="GIX84210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12955" checksum="6D31DEFED9055378" modified="2024-11-27" version="1">MDDVQSCNSMISSNNNYFKSSKSINELVLRLGQKSFEEIHIVCQHRDAKHKIPRSNPFLIQADIKKHINRHDNITNMKFSRQGKLVFSTADPVCAAQILNLEKFKKRPFLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNR8</accession>
    <name>A0AAV4NNR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_703471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003512">
        <property type="protein sequence ID" value="GIX85415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10857" checksum="2ABD647246F3901B" modified="2024-11-27" version="1">MKCDNHLHGDDSSCSRRISFTFARYLDGVERGELPINTVADEQQQQQQQQQQQRRMRRRIWTWNRLSLTAETVYWTRFVSRNTMSNTQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQW6</accession>
    <name>A0AAV4NQW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_321101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021227">
        <property type="protein sequence ID" value="GIX87355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10157" checksum="A6496C239F87E16F" modified="2024-11-27" version="1">MTCPDLVLEYTERPELCTDERVEPMVLLDILTAQRPFGAYRTAGCRVPEVQPEVNRSGALAASLPQAGDSACRGRQLLTRSRKTAPILRESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTJ6</accession>
    <name>A0AAV4NTJ6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_406021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021199">
        <property type="protein sequence ID" value="GIX87048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10288" checksum="1D3B254B597F7CE3" modified="2024-11-27" version="1">MEFKTSSTSLLRRRPPKRMPQGCVPTERLISGLVGKGKGKVSQQSQIQILVTNHQTGHGTEEKKSYLRKKLFANLEDWKSLSFHTHKGKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYH6</accession>
    <name>A0AAV4NYH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_260168_1</name>
        <name evidence="2" type="ORF">CEXT_2701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003790">
        <property type="protein sequence ID" value="GIX88664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19090" checksum="011A99F4298D35F5" modified="2024-11-27" version="1">MTLPLKDSKANKRHVNAEWDSNGDTLPRNFPDGLKMVKKKKKESDHTRNEIGGGTRRVGREGGERESRSLVAAAEDNSDSIRSKWAVKRLHLLKVGKSATKRENWPARPSCPRRTYFGSLPPSDIPGDDSVFTSGGRGEDIDLFQLPERNFRVWGELEWFRKLALFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P197</accession>
    <name>A0AAV4P197_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SUEL-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_142171_1</name>
        <name evidence="4" type="ORF">CEXT_392101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021467">
        <property type="protein sequence ID" value="GIX89976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P197"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22829">
        <property type="entry name" value="Gal_Rha_Lectin_EVA1_EVA1C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.740">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000922">
        <property type="entry name" value="Lectin_gal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043159">
        <property type="entry name" value="Lectin_gal-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46780">
        <property type="entry name" value="PROTEIN EVA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02140">
        <property type="entry name" value="SUEL_Lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50228">
        <property type="entry name" value="SUEL_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="SUEL-type lectin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX89976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="301" mass="34140" checksum="C3911A6F4EFF4F5A" modified="2024-11-27" version="1" fragment="single">DIQSSCREKQKCHLKISSELLKEDPCPGVQRYLNVAYKCRPSKFFTQAGADECPEEGNKKYEECEANFATETAMNSCHGRRRCSLSADPIAFGLPPCSAKARIFLKVVYTCDSLQDLEFEEENDLDYPSIFKEPNVSEILHNLKSADNLNIKVTTPSYHHKDTVDLTLATTTKVDVQSDETSDDSTDVNCTVVDDNQKVRTKEKFILYVTLSLGAGILLFLLVLTVRLYSQQQRTLKKAKLNVSEPLPTFEDCSDLEPFDPRQDNSVEVVRYTNMSTIRRQDSTSQPRAPLSHSMNNYYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5G5</accession>
    <name>A0AAV4P5G5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_289531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004130">
        <property type="protein sequence ID" value="GIX92467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5G5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14952" checksum="80BBB90B82B7A974" modified="2024-11-27" version="1">MKGIDMRQFRFYKVPESLMPQTEEEVAEFLEKGLIELSWVEIAYHWNTFRIKMIPILKCGDYTELKAHNELSPSQFKIQDNSGIINYLKIFFEGNSTRKRASREFTSFLSQKGQINMMPQCHLVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBQ4</accession>
    <name>A0AAV4PBQ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_276431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004408">
        <property type="protein sequence ID" value="GIX94687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16920" checksum="38F44BAD8876D8E8" modified="2024-11-27" version="1">MYPTRRDGGNVLAHFPGFNYGRFIVFFFFFPFFLSLSLSLFPDIRSKLHNNEIAFNQSSVLLFVRSVVSEFLQPITMSSRNSETPLQKKRCRDGNQGSLCCAPSFKSLLLSRGVNEESLVRKMIGILICLVSLASPNFWGGCASTSYRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBS9</accession>
    <name>A0AAV4PBS9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_93781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021706">
        <property type="protein sequence ID" value="GIX92607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10611" checksum="A7AE33BC16D88CEA" modified="2024-11-27" version="1">MVRFELKFKLSASISGLLAGASATRPLVAEESHSRDSFADRFHPRISHSANYRRDHCKCNRNQTRDFFLRKVLRAMLLTYAINALTEPCSPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PT92</accession>
    <name>A0AAV4PT92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_202195_1</name>
        <name evidence="4" type="ORF">CEXT_630601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004906">
        <property type="protein sequence ID" value="GIX98427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PT92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX98427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11553" checksum="13D5DE53DE4C2BB3" modified="2024-11-27" version="1">MSRNWACIDSHLWCDGVNHCPSGFDESHANCHPLAKGIQYLSLIITMSAIVLFISGVLVTWVLIRHRHKHRSSSTDTDDRTKDYNNRLTPTEDYPMENHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0L2</accession>
    <name>A0AAV4Q0L2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_22733</name>
        <name evidence="2" type="ORF">CEXT_662041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005363">
        <property type="protein sequence ID" value="GIY01727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0L2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="355" mass="40919" checksum="6CAEFE2ACBE52196" modified="2024-11-27" version="1">MNYDDRKKQVMHKRCCLFCLKPGHMAKKCHSNVGCLICERRHYVLLCPDLRKGIPKSKVADEEAKSTEILLTNLPSEYEIYLKTIIVRLRHKGKEVCVRSLMDDGSHRSYIEKSLSAELNLSPSGTEVLSQGLFGSGISPAADFQPEDRNFLRFLWWNNEDRSKLEFFRHCRVVFGVTSSPFLLNASIRHHLDSTEYQIESLQATVKKLKEKYAQTIQSYEENKILKVKSRLILGEDFVRLAVLPDHSIVRRLFDYIHQKLQHAGMQTTLSSLHGPVPLPANRINRVAAFEVTGTDPTGPVFLNGCQKAWIVIFPCSVYRALHLELVTFLSTEAFLQAMRRFFCEERTLFCYVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q371</accession>
    <name>A0AAV4Q371_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_536751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005637">
        <property type="protein sequence ID" value="GIY03885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q371"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="52" mass="5814" checksum="7F82B163909416D3" modified="2024-11-27" version="1" fragment="single">MDNQKATSAKFKEWNLNYIKQPECLILAVTPAEQDLATSGCSDKSQRTVDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3P8</accession>
    <name>A0AAV4Q3P8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005506">
        <property type="protein sequence ID" value="GIY02822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3P8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10553" checksum="D631F9F8042011F8" modified="2024-11-27" version="1">MGSSCTVRGKGLSNSLPKKNSFFLGKCIKCRAHKMGNFSKFPEPFLSHTLPFSAPSFLFISNSTPQPFPQKPFYFICSQQKLGRYLIRTEPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5L3</accession>
    <name>A0AAV4Q5L3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Voltage-gated potassium channel subunit beta-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">KCNAB2</name>
        <name evidence="5" type="ORF">CEXT_669191</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005732">
        <property type="protein sequence ID" value="GIY04597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5L3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015459">
        <property type="term" value="F:potassium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044325">
        <property type="term" value="F:transmembrane transporter binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901379">
        <property type="term" value="P:regulation of potassium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="135"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY04597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="314" mass="35553" checksum="517E115B1F5556DF" modified="2024-11-27" version="1">MRVDGSLSSTNRAPIAILECMEEGLLPSEASMAANPMSRQVSLSYPAPMRYRMILNKILTSGLFFRNLGKSGLRISAMGLGTWVTFGSHISEQMAEDIVSVAYENGINLLTRQMFMLVERDLRITSQLSYSGVEGLQASLERLQLSYVDIIFVNKADPMCPMEEVVRAFTHCINQGMAMYWGTSRWTAMEIMEAYTVARQFNLIPPLVEQTEYHMFQREKVEIHLPELFHKIGIGTMSWSPQAFGMFTGKFDEGVHLLSRGSVKVRNFTMLQEKACPEEGRSPRHQTKIHELSLLAEKVGCTYTQLTIAKVNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAW5</accession>
    <name>A0AAV4QAW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_296831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005930">
        <property type="protein sequence ID" value="GIY06136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19913" checksum="CE1F74CB98BFA915" modified="2024-11-27" version="1">MNKFGLFGFINVCNQMVIKAGFTNLDESLRNSTECLEDFLHIFELLKEGDLEAKKWLPTPWMQQLLQFPSSGSLTSPVRKDISFIGACFYNSLHPLLFSICVAWFLFKCETGQAGIFGRILSNKAFASIGRYPSPLWHPIVMDFFYLMQRSTVVYTHFLLVFSAGSYPIKRLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHV1</accession>
    <name>A0AAV4QHV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Netrin receptor UNC5C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UNC5C</name>
        <name evidence="10" type="ORF">CEXT_470321</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006258">
        <property type="protein sequence ID" value="GIY08506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000037">
        <property type="entry name" value="Unc-5 netrin receptor C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057755">
        <property type="entry name" value="UNC5A-D-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25609">
        <property type="entry name" value="Unc5_NetrinR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Netrin receptor UNC5A-D-like N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY08506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14729" checksum="0398988DD40C4520" modified="2024-11-27" version="1">MLVTSTYAYGGFLLDPLPTEDPEPSTTPVFLEEPLDSYIIRTKPVTLSCKARHALQVYFECNGRLAEDRQHSLQQYVNPMTGVRQMEVSIDVTRGDVEKILAGDIYVCYCFAWSSTGRIKSRKSVISLACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6D6</accession>
    <name>A0AAV4R6D6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ycf1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_230131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007280">
        <property type="protein sequence ID" value="GIY15762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6D6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="54" mass="6417" checksum="779201ED6EE2E854" modified="2024-11-27" version="1" fragment="single">MYVEGDQRSPDEKNVFRSTKKNNLRRDNKLKNKDEIERSGKTFGEMQISNRKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RE38</accession>
    <name>A0AAV4RE38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007700">
        <property type="protein sequence ID" value="GIY18951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RE38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19873" checksum="BF93BDE61443FAF5" modified="2024-11-27" version="1">MAIFQNISRPFVKLEKFCKQKVFLTYANIRIDISETMQGTIWPKTIHTKGTPHLQKKKKLQRVIEKERKGRDKKKIPSRISQKQKGKKNSQQKGKRMQNSWRQRDFKALEAVNAFSILFPFTKSSSGAEDSGESIDSGTVFVRENLRLTLMKGPKLLLQLQFLVLSFTKLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4REV2</accession>
    <name>A0AAV4REV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_44594_1</name>
        <name evidence="1" type="ORF">CEXT_851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007898">
        <property type="protein sequence ID" value="GIY20503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4REV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17117" checksum="C7E533475A08D2F1" modified="2024-11-27" version="1">MAISCPSRCPFQVAGQQTPMCCFGNGKYEETTWPTKSKRETWSGLWSEVRNGVCPLFTTRDQRLVPELPVFTSSGKESFALSVRFCLPPPPLPPFFLLHPQGCLGKGCESQGHSFQIDPRESFARPPGDKKYCFWGMFSINRLGVKFFLALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPB5</accession>
    <name>A0AAV4RPB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_520701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008315">
        <property type="protein sequence ID" value="GIY23803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8672" checksum="9397F88A231EBAA3" modified="2024-11-27" version="1">MTQKRPSRLARRIWARWRYLHRGGSCAASNDDDKPRTTCVDSGNLHKEVIRPAGELSLITWGPICPFVIARIISLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPZ7</accession>
    <name>A0AAV4RPZ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008243">
        <property type="protein sequence ID" value="GIY23189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13258" checksum="4D99F072EE6CC4B2" modified="2024-11-27" version="1">MNDVFFSLIFHWPKLDWASDLSMLHQMAHENHNHPVKTRLRCWTSTPKRDRRRAIWESLVRKIGSLLFEIGQEQNRAARKMFKCTRINSRRLGVWFYFCVPASSGNRIVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQS3</accession>
    <name>A0AAV4RQS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_586951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008135">
        <property type="protein sequence ID" value="GIY22323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9075" checksum="2A0C8094F642EA04" modified="2024-11-27" version="1">MTCTIWTKAQLHVISETGQTSEIERTPTEKEMLDPSYQDQVDIDSEIILPKYHRRYFSIIKDNLNNFTIDTIEDILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSY8</accession>
    <name>A0AAV4RSY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Matrix metalloproteinase-24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">Mmp24</name>
        <name evidence="18" type="ORF">CEXT_672591</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="13">Can bind about 5 Ca(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M10A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008418">
        <property type="protein sequence ID" value="GIY24517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030574">
        <property type="term" value="P:collagen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00094">
        <property type="entry name" value="HX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04278">
        <property type="entry name" value="ZnMc_MMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000022">
        <property type="entry name" value="Matrix metalloproteinase 1, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.110.10.10:FF:000007">
        <property type="entry name" value="stromelysin-3 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.110.10.10">
        <property type="entry name" value="Hemopexin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000585">
        <property type="entry name" value="Hemopexin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036375">
        <property type="entry name" value="Hemopexin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018487">
        <property type="entry name" value="Hemopexin-like_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018486">
        <property type="entry name" value="Hemopexin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033739">
        <property type="entry name" value="M10A_MMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201">
        <property type="entry name" value="MATRIX METALLOPROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10201:SF291">
        <property type="entry name" value="MATRIX METALLOPROTEINASE 1, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00045">
        <property type="entry name" value="Hemopexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00120">
        <property type="entry name" value="HX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50923">
        <property type="entry name" value="Hemopexin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00024">
        <property type="entry name" value="HEMOPEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51642">
        <property type="entry name" value="HEMOPEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 18" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase metallopeptidase" evidence="17">
        <location>
            <begin position="231"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="Hemopexin" evidence="16">
        <location>
            <begin position="419"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="repeat" description="Hemopexin" evidence="16">
        <location>
            <begin position="465"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="Hemopexin" evidence="16">
        <location>
            <begin position="511"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="repeat" description="Hemopexin" evidence="16">
        <location>
            <begin position="564"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cysteine switch" evidence="15">
        <location>
            <begin position="208"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="binding site" description="in inhibited form" evidence="13">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="564"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphotyrosine; by PKDCC" evidence="14">
        <location>
            <position position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR621190-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY24517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="715" mass="81071" checksum="0B2AFE1DA9CE8781" modified="2024-11-27" version="1">MSTWHSLALCSYSFGAHLCHLDTTSDILGLRHKHQNLPLSDKYDLALKHQINLSTMLLVSSTFRNTRAHTNASRQELSTLWPSAVSKNETPPEANEYGLLKETLYLIYQEKQDYDNNLSLSEDRLLYSTSPPGTLVSWAPLLRNVLQVSILFQMYLQKYGYMNESGSNSASLISEKAVRSAIKDFQRFAGLAETGELDNTTLNMMNMPRCGVRDKVGHSGSARRKKRYALQGSKWRVTDLTYRISKYPRRLKDKQKVDKEIAKAFKVWSDVTNLKFINTDKGRVHIDVRFEEGEHGDGERFDGPGRTLAHAFFPQYGGDAHFDDEEKWTINQYYGTNLFQVAAHEFGHSLGLSHSDVKASLMAPFYRGYEPSFNLDEDDILGIQALYGRPRKEVALPTPGYRPHATPDYSDGSPDLCQDSAFNAATTTEDGKTYVFKGDYYWEIKQNGISDGYPRKISEDWGGLPGNVDAALTWTNGKTFFFKKNEYWRFRNKKMDSGYPKAISVGFEGIPNNIDAAFVWSGNGKTYFLKGSSYWRFDSRSEPPVSSRYPQSISNWEGLPNNIDAALQWVNQKTYFFKGRSYYRFNDRLFSVDKADPPYPRSTSVWWFDCKAQSSNEDLTKASLNGDEKHPIYIGGEDNITSSTQIPVENDYVDSDVVDGSEKQDVDLQQGEDDAATPFPHQEALDANSARNSCASLFLTLLLIAVVQAQKWRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUB7</accession>
    <name>A0AAV4RUB7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_351821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008471">
        <property type="protein sequence ID" value="GIY24967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="10073" checksum="FA08600ABAD9BBF0" modified="2024-11-27" version="1">MERMVNFRLEAFLDSINAIHDEQAGFRKHKSAIDQVNKRSQQIKDGFHRQMSTLACFIDFKEVYDTVSRKLLYKSKFTTELHETC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVU3</accession>
    <name>A0AAV4RVU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_625031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008546">
        <property type="protein sequence ID" value="GIY25462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10948" checksum="EE56078161D67117" modified="2024-11-27" version="1">MRYRFQMYRKHFCCDVYIDEPTFMRCCSGTYLFMCLTQSVNKAVDACFVHGIALDGILRDQELNAQILGRKCFTYLKCRWRHVHMISIISHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWN0</accession>
    <name>A0AAV4RWN0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_616301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008459">
        <property type="protein sequence ID" value="GIY24872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8846" checksum="724FB4D2722C2CF1" modified="2024-11-27" version="1" fragment="single">MSENKSKITCGVTPEWLCGCPSECDLLGNKSVSNPRESWLPILECYVCLNKNLFNPQRVVVCQLPIPENVMSACGQLTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIZ1</accession>
    <name>A0AAV4SIZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_83863_1</name>
        <name evidence="1" type="ORF">CEXT_645311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009570">
        <property type="protein sequence ID" value="GIY32949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.30">
        <property type="entry name" value="Haemolymph juvenile hormone binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010562">
        <property type="entry name" value="Haemolymph_juvenile_hormone-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038606">
        <property type="entry name" value="To_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008">
        <property type="entry name" value="PROTEIN TAKEOUT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008:SF9">
        <property type="entry name" value="PROTEIN TAKEOUT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06585">
        <property type="entry name" value="JHBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00700">
        <property type="entry name" value="JHBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="27451" checksum="5A6D3F3D416ADC65" modified="2024-11-27" version="1">MSPSVEGSAIIEEEAEEYDEKLSEFIKEILENFREQMPEGILDIGIPPIDPLVIPNINEDINEGVAQLTLRMRDINITGISRFHIEELKADLERGFANFSITLPELKAEGDCYMNGKILNIFPINSDGPFFIHVTEVAIKGYGDLNVSTGGDTRLHMNDLRLSLTFGPLDMEFKSLLGGGRWTQVLVKLLSGLGRNLFQHFHKEAMTELNKALLKLINKELDKGTLSELLDQIPLGAPERISIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLJ4</accession>
    <name>A0AAV4SLJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_86951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009835">
        <property type="protein sequence ID" value="GIY34950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9285" checksum="A69908653AFFA5C1" modified="2024-11-27" version="1">MTPKADNRIPFHHLTFTTPPHLNPRISANVFISRIRIQFGLTPSRQLIEVSVPAATMLLPDIREFKLKSRHPVPLVCLFFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SP65</accession>
    <name>A0AAV4SP65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_515051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010021">
        <property type="protein sequence ID" value="GIY36233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SP65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16038" checksum="85C54CB8BD95B0EF" modified="2024-11-27" version="1">MGVNCVPSEISALRHEWMGLPLSSKFSSGHEFWMIIVKRPSCDRYKCATTVFSCFVRSQGPRKPFDIPLINPRTFGPGPHLFVHLDLLNLGIPTGCALNPNDGWNERVNKNNDVFWEVLRSGKWCTKLKTCGKKCLIDAVDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SPN7</accession>
    <name>A0AAV4SPN7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bro-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_748851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009782">
        <property type="protein sequence ID" value="GIY34527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SPN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003497">
        <property type="entry name" value="BRO_N_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02498">
        <property type="entry name" value="Bro-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01040">
        <property type="entry name" value="Bro-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51750">
        <property type="entry name" value="BRO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bro-N" evidence="1">
        <location>
            <begin position="87"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY34527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="29004" checksum="4E0F303C7899498D" modified="2024-11-27" version="1">MHWLVRIKRFSKLKHPGSIKALASQEEIPELVELSTTSLHGRPKPRAPRHHTRWIIRCCTLLVERKNKLLWTFQMAQHDSFLYNAEQYDISYIMDKDNSPWFKVDDIKAILEYSSCADHQKEWYEIGDPGNEDPYTVFIDKSGLLQWLSSTIETPIVAEFKRWITNKLLPMIRGPHILKIYKKNTSNVYIFVQDYKDNIEEATKNINMRSFTLFLEKNNIPPDKNVCEMLKPIFPNVTLTSVQEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STG5</accession>
    <name>A0AAV4STG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_788231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009959">
        <property type="protein sequence ID" value="GIY35780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="14185" checksum="03AB08E9801465E9" modified="2024-11-27" version="1">MVQDFDVKEMFLQRFLLSAEKFRHLSTTCQLNEKEDPTRSERTFLDVRCNWVTPEDLVQKLDTYTNLRKQDIQADVRKLISNKNITTQLSKKRIFKCAERKTKTTSRIINSSCCHLQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWS0</accession>
    <name>A0AAV4SWS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_602151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010374">
        <property type="protein sequence ID" value="GIY38918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10360" checksum="95C9B24A37BF0DF8" modified="2024-11-27" version="1">MCYGQRIQKEMHLDPDEARSLNRLGGRDVRSDKGPSVCPGPCYQRSSNGKREIWWGLAVDFDFVLGKKREKCNCSEALTEVGKWSITLKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2K3</accession>
    <name>A0AAV4T2K3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_56591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010496">
        <property type="protein sequence ID" value="GIY39681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2K3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="13904" checksum="6C830905178D2819" modified="2024-11-27" version="1">MKAFQSSVLCPSFAAPRLSALSVEGAARRNSPIKQMPLSMHFQVSENSLRLFLFHDGSPTVHYHHHIVCTMNNTMCITLVHAHLQRAIIVIGHSCLCLIILPCTSVMVSSPAALDSSPHMDRILFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3J1</accession>
    <name>A0AAV4T3J1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_747781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010699">
        <property type="protein sequence ID" value="GIY41203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11061" checksum="F67E88D054797AAD" modified="2024-11-27" version="1">MHKETFSPQMRARSELAKKNTDPPFILPRRHDRVRVTDCSRRNKRRKTLLTEKKPRVFVCCGFPPVYGYRTARQRHVGRGGSVPFIPPSGSIRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3K7</accession>
    <name>A0AAV4T3K7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Antifreeze protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_59521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010439">
        <property type="protein sequence ID" value="GIY39267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043864967" description="Antifreeze protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="8163" checksum="9F0F527DF9C96633" modified="2024-11-27" version="1">MIAKVALLLAALAAVDATVLAPGLLNAGLLNAGLLAPSAITTGSVVSIPGAVTTDKRVIGTTGLIGASPSSSAMDSSETVFSPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T867</accession>
    <name>A0AAV4T867_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_219774_1</name>
        <name evidence="2" type="ORF">CEXT_87221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010739">
        <property type="protein sequence ID" value="GIY41691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T867"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="43146" checksum="B2D97AB3FAA0540E" modified="2024-11-27" version="1">MPPTLPSTFLDAHGNAEVISFCYKNVIRGGTLKLKKKKLLPDENPKIVGSQPRYEVGDIVNVTMQRRTLEARGNLKWYINGKEADAGMERRHAPEEHLDGLSTSSLGLRFVVRPRDLREGGALTLRCTATVSQTYSTASEELVVGDRDPELLSSPPNPFSSRGVEGRPRDHGVGHSTAWGAAGRQLLLRQAAPAPELQWFLNDKQVEPEQVVRYDHPAGVLGLKLRVEARHLDENEEMRLKCTATLSRVINTRSQETTLGGNHRTSGLTVAENFGKVSERSSSTSISNSGGALTTPSGPPWCWWGACWWRPCFDPYEQRTPRVENQRAKNRRAGLSPGAESLLWSFIFCLCRTKDNCVMEQLAHGIFASLPDTAVRQESSLHRTTVSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFL0</accession>
    <name>A0AAV4TFL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_93911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011071">
        <property type="protein sequence ID" value="GIY44004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14962" checksum="F16D36CF3487B27E" modified="2024-11-27" version="1">MFNYIPPSSVIDFSCSTKRTLHLAVSFILHSKLDRNSFEIEGRRVQLFTFPVYSTHELNFTSSDSLWMLAKALFPTPPSLIKTAAFRNHLIIDYGERTEQSLFCRMLLCASPLGHSPTCRESQFSPSDKGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGN9</accession>
    <name>A0AAV4TGN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_28471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011275">
        <property type="protein sequence ID" value="GIY45480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12123" checksum="0712CAEA285E188D" modified="2024-11-27" version="1">MSASTSDLTFRFSFFSIDMVTSGTKLTWLSRNDSLLNLDKLAVISIFPLRGAVSIIGADALNSSNDFMSVTVVVCGYGGDDLSKIYSEGEIAKRMALLEILHVAERYFSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGU4</accession>
    <name>A0AAV4TGU4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_636971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010947">
        <property type="protein sequence ID" value="GIY43203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10923" checksum="43288E53C8A28D4B" modified="2024-11-27" version="1">MRYTCERFEKLFIASTLFTRYLVQCALLVMSRWLSVQLPASLVQQDRSSWILFESGVPFQSNPEYIQRSNLHANKREAVSQISHHGWGIISESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJR2</accession>
    <name>A0AAV4TJR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_433761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011447">
        <property type="protein sequence ID" value="GIY46620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9994" checksum="AD6F6F331BAE222B" modified="2024-11-27" version="1">MIQPKILLQTTWKAKESWDEETPITLYPLTQLVASRRQQISGWDGDNNTMEDYWNFLKQSPGCIEKPLHYSQWKSLWESIRVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TL18</accession>
    <name>A0AAV4TL18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Brahma-associated protein of 60 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Bap60</name>
        <name evidence="2" type="ORF">CEXT_433221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011374">
        <property type="protein sequence ID" value="GIY46136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TL18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="349" mass="37558" checksum="F87365735CB8E854" modified="2024-11-27" version="1">MYNNSWRDMASNMNRGYPVPNQNPVPVSGVPPPGPAPVPVPTPVPGVVPNQPGAPPSIPLCIKQEGGANSPLPPTAMGPVPPPVPGMRPPDRPMGLQHAGPPPNRQYGTPAPVYQHHFQPQPQRPAYPPGSPAPPPHGRVGMGPPTNTYAGGPRASQGPMGPMAMESRKRPAPDRLDGRSQGASSSKSGPPQSGSGSSASGPASGSSGGSSKKKKKLAEKILPQKVRDLVPESQAYMDLLTFERKLDSTIMRKRLDIQEALKRPMKQKRKLRIFISNTFYPGKPEVETGEEPSVPSWELRVEGRLLDDPNAPKADQSKVKRKFSSFFKSLVIELDKELYGPDNHLVEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TN09</accession>
    <name>A0AAV4TN09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized serpin-like protein TK1782</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TK1782</name>
        <name evidence="6" type="ORF">CEXT_121351</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011430">
        <property type="protein sequence ID" value="GIY46501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TN09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.497.10:FF:000001">
        <property type="entry name" value="Serine protease inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Serpin" evidence="5">
        <location>
            <begin position="23"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY46501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="303" mass="34982" checksum="CF7DEC06C10E1F62" modified="2024-11-27" version="1">MESEISKKDAEKLALANNYMGLLLNNLFVKEETNVVFSPFSISIALAMLFYGARNETAEEIRNVIGYKFANVKDDKPKAYFQKFLNELDNISDSYTLTCANTVVSDKEFKVKRKYISLLEEYFKAFFQEADFNNEIAEVVKLINEWVSKKTCGMIPTFLESLDPSTVMVILNAVYFKGSWMHQFDKEKTSLQRFYNKGKNGKKVEMMHLTNNFSFVEKESFKALQLPYKGEEISMLILLPNLKNGLEKLETSLTPNFVQDLTQEMINRKVEVALPKFKLEYFKALKKFFISLGLKTSIWSCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TTT2</accession>
    <name>A0AAV4TTT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_324841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011815">
        <property type="protein sequence ID" value="GIY49274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TTT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11219" checksum="212B6AAC6AB9F5B2" modified="2024-11-27" version="1">MKQPPLYYQSASYITQTLLYHPIRYKRRETGVSFWVLQQMPEDCTIRRQVKPGDRRIIECRTPSTTPVVSFVIAEAQTSLAHEIRFRLHKIVTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4G5</accession>
    <name>A0AAV4U4G5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_513541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012266">
        <property type="protein sequence ID" value="GIY52633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4G5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="63785" checksum="1887D53C3063B493" modified="2024-11-27" version="1">MQDPHHGEVRPRSYRLRWQITVLSNIWQPTQEFFHTELETLTRWHIFIHSVRDAKGGSRFCCTVGYDSLVPAHRQTIQARFSGIVSMDTRTLSIINQDHQFSSGDGTSSLAWNFAVPFVMPNTIHNLIFEFVFTINVRHFAIYTDHEMAYLTHLSDDLLLMMSETGYRMMSLVTAGFPEVREVHPFILYSRWRNFNKVHQITGWSVMVPISERVLHYILTFLYRGIIPTLLLESRHSTELSQVIHIYQLHILKKMLCLYLETQSRVDLYNSTTSNSTVSLKFERIDSPPVQRRQSMFPIAGMGNFVFVTVTVEDVDGIGPWLSYRVSSCLTTDLEYEICISVRKNKKKEILAHYAYNTVRGLAFTEERLVLFLGSKHIFGNFLSSDERMLLSIDLTYSVALPRYNLTDTSPIAEPNNAVSLWDLATDLWSALKSGLHADMRVIPQEPSETLKATSCNRFMFRARLKRWDNIMTAQQMSGNDIPTIHLPLNDFCVEWLLRFMYTAEARPVPHGPRMELTRFAVENDFASMLSLLNQTDFELLFGNLLRSRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8M2</accession>
    <name>A0AAV4U8M2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_739831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012471">
        <property type="protein sequence ID" value="GIY54111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8M2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="18048" checksum="45C042998D1D3921" modified="2024-11-27" version="1">MKFRIPVPRRISSYDSASLFACQLLPHQPLRAHISTSTRRDRQFNRVTGRVKVSSPEHMLFAYLVHIHYLCVFFPSFFQSLKFFRSIRLQIVLCVGRHEMILTHVSYGKRKNAERINLVSIISFMSNSRVTELQERWILEYRGFNRIASRMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEI3</accession>
    <name>A0AAV4UEI3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptide-N(4)-(N-acetyl-beta-glucosaminyl) asparagine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NGLY1</name>
        <name evidence="2" type="ORF">CEXT_368171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012746">
        <property type="protein sequence ID" value="GIY56230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1020">
        <property type="entry name" value="Peptide N glycanase, PAW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038680">
        <property type="entry name" value="PAW_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006588">
        <property type="entry name" value="Peptide_N_glycanase_PAW_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04721">
        <property type="entry name" value="PAW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAW" evidence="1">
        <location>
            <begin position="6"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="PAW" evidence="1">
        <location>
            <begin position="62"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18376" checksum="34B96AA221570331" modified="2024-11-27" version="1">MKVTVGRTSGSLAWLIARSESGFASPQSAYVFKLIPEEIKQRHFHVQYCSASDKYIRANTSINIEGHGLVISKIKMNLMSKTFDCGNVRWLLFPNPYKESPVHLTAGIHPIEITELAGITGFTLTAELIAGDKWQNAQIFRQSLDSTTFPFEVEIRFKNIKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UIW7</accession>
    <name>A0AAV4UIW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_441331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012923">
        <property type="protein sequence ID" value="GIY57544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UIW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10833" checksum="2FB5D3AF3BF83380" modified="2024-11-27" version="1">MCAVALLSNELLPFSVLWQHCTFLGYCTEGRLSTHFSTSLLFFFLFINAYPSPPDEELGQPSSARQSNMQHSEYDGFQKVLSQKEIVNVENVQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPJ9</accession>
    <name>A0AAV4UPJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein-tyrosine-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PTPRJ</name>
        <name evidence="1" type="ORF">CEXT_486941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013225">
        <property type="protein sequence ID" value="GIY59645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18754" checksum="E10EF4A0860AA521" modified="2024-11-27" version="1">MHNPWKKFARASQGWTSTCWSAEVAEDCLKEWNVTHEASLHFAWDGEDRENDVMFFVDPVTVGDDITDCRNQTLKAPFSQKIIWIEPLCSNTTHWITASQICADNSTSQEKKFEINSDYLLAPSNITTVEVTNTTIQLEWDQPYADAHITAYQQVWYPTLSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URG0</accession>
    <name>A0AAV4URG0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HCN2</name>
        <name evidence="6" type="ORF">CEXT_773711</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013260">
        <property type="protein sequence ID" value="GIY59985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098855">
        <property type="term" value="C:HCN channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003254">
        <property type="term" value="P:regulation of membrane depolarization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051413">
        <property type="entry name" value="K/Na_HCN_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689:SF5">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ion transport" evidence="5">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY59985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12094" checksum="9B65E8ABFC977656" modified="2024-11-27" version="1">MLLCWPSLFFNDDLSTRWIAFNCLSDTVFLLDILVNFRTGIMNQDNSEQVILDPGLIARQYLRTWFFLDLISSIPLDYIFLIFNQDYEENYQLLHAGERCES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWR3</accession>
    <name>A0AAV4UWR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TBC1 domain family member 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Tbc1d25</name>
        <name evidence="4" type="ORF">CEXT_743071</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013590">
        <property type="protein sequence ID" value="GIY62188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901096">
        <property type="term" value="P:regulation of autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF333">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="198"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="620"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY62188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="738" mass="86275" checksum="8139D78AC0DD741B" modified="2024-11-27" version="1">MTYDMSDILDLHLKHYVKVKAKMLQKDSGQKRGPYEYFSLDPQTANYIKLRNQLARIFNIEGEFTIHFKKDKSFIPLTSDWDLDGAISEYSKPHLSLAVELQTIDKALEEWDIICPADIISMDDQENARCSQERKSLAGSIISHVETAMLRVTRVLSLDKGAVRSKPPMDEAEYSSLLDREGRLVNQRELHMSVYKGGVDPAMRPVVWKHLLNVFPQNITWEQRNSYMSCKCEEYYQLRYRWQHLMQAGTIPTVLQDITTMVRKDVRRTDRTEKFYSGTDDNCNVRALFNILTTYAVNHPNVSYCQGMSDLLSPILYVMKKESEAYVAFCGLMKRARTNFKLDGRAMKLKFRHLQKMLRFYDPELYQYLEQQEALDLLFCYRWLLLDLKREFPYTEMLNIIETIWGSLPPRPPQTELELYDVKFPTAAICNSLKDRTTQKDYLKIDEGHFASHHDVNSLSQSVTNNINTEEIKQWQLRVRRESMARNLVHHDSCSEGEIRLPVHYKKRKFRSYIAGKLIRLNKHPSSPLTIRSCKIPERKKSLQTEICQSWACGEVFGKVEEKSRVRDALYDAREFLRNQWCYSNTVNEIQLNNWLNGRRFEMKPGTIGGIEADIADVNNRQRHGSSDSNYSTISEDLSEADEESSTPSRSRRSRSEGYMSKTIPKKLPLWLTMTTTMLMNQTTNSTIQTKRITTSWIRWLDASTKRWMRISTGRKKCCHHPTYLEMAIPFYFSYALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8J6</accession>
    <name>A0AAV4V8J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD repeat and HMG-box DNA-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Wdhd1</name>
        <name evidence="8" type="ORF">CEXT_332431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014098">
        <property type="protein sequence ID" value="GIY66224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21993">
        <property type="entry name" value="HMG-box_WDHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055339">
        <property type="entry name" value="HMG-box_WDHD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="7">
        <location>
            <begin position="5"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="5"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="206"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="6">
        <location>
            <begin position="382"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="906"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="771"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="960"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="802"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="967"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY66224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1038" mass="116331" checksum="A4F6A91248B788A6" modified="2024-11-27" version="1">MEDMRYAHNDGHTDVCYDDSGKYIITCGTDGDIRIWDGFEDDDPKSHHMGNSVSAVTFKKDLIYLSADSFKVEAYTFPEAEFEQIVAQFSTSIYHIVCSKDGKIVACGGGDFVIKVFDTSDKSLMTFNGHNGPVLSVAIDPEGKYLASSGCDGTVRIWMLSSQECIKTLNLFKKSNDFEVRFYERDIWESKWSLSDECVTQTLSIVTYSPFGKYLATASMDGKMLVWDVETKKCITKKFHEKEIAICGLAWHPSGKELVFCDVEGQMGIYSSPFSSSSNKEDIDIPLVTVKKFKDFIDDDVEVDGEDDDVEDTIDDDGDIRIDDDSDIGIDDDGDNAFDIGAIKASLEPKIFGEDLEDVKIINKEPEPKIQIIEAPKLPVQKPFQPSSTPINLDQRFMLWNNVGIVRCYDTEEENSIDVEFHDANVYHPLHINNTRNHTLAALSTEALLLSSPKLEENTSKLECLHFNTWDSNKEWVVEMPENEEIEAIALGDDFAACVTDRKFVRLFTISGIQCEVFLIPGPVVSCSARGNQLLIVYHKGLGIESDQCLNMMIVKVNLGSQSRAKECFVPLSSKAFLSWLGFTDEGTPCIVDTTGIVSLLNASSGSKWVPISDTSANMKGKSGTYFVLGLSEIKQEIRCILCKLEEENQRYSLACKRMELLIKEGFDLDFELNSIQKKHMDVLLKMFALATRSDREFRALDAAELMPNPVAVQGAIRYATQRHRIALAERLGEVMNKKICKETEVEEEIEEDFDLPAYEDLSESLISRNASTPNLSSYSKDDSVLKPKPLSRMRGQLEKISEDDEEHAVNEEESNIPSAKNISLMPKSSPVSNPFKASSKAPVKKPEIGNLNSIDEILNNSMNARNSSFTSGKRFLQPKKSRFPTKKNNLLKKTADDSSKQKFGFDLFLEENREEIKASAPPDTTDKELIKIAIKMFKELPKAEKQKYQKNFSSNGIKENIAAEAKSPHSQKELDVKESDAERITNGSKESVGKRKEIDNSDDVTAKPTKKIKTVSDKLSDTTVRKLTQFAFTKTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9B8</accession>
    <name>A0AAV4V9B8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_351741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014122">
        <property type="protein sequence ID" value="GIY66494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9B8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10716" checksum="199951BE0B297AC2" modified="2024-11-27" version="1">MRIEKGIHKRCYEPRNKRKNLKWEFKTPFEIFKRRNKRLVFYSILASEYANQVLIPPSAQHPLPSQLLNRLPVSHPLPPDCFPSSVGMATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFX1</accession>
    <name>A0AAV4VFX1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein toll</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_13682</name>
        <name evidence="4" type="ORF">CEXT_722611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014502">
        <property type="protein sequence ID" value="GIY69182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFX1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF170">
        <property type="entry name" value="RE50361P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY69182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="465" mass="52539" checksum="B7E5D8DA3DF2ADA9" modified="2024-11-27" version="1">MATLDLSYNLIEQVTNQSIQFGNSVELDFTGNQIKEFNAELPYNVKRVYLNKNLLTSLGRTLRFSQMTEVTMAYNRIQNLGFEDLRGVHGVQDLDLQGNVITSVERFTFNNIRKDLIYLDLSQNKIRTLQGCVRYLSLLTSLNLTDNQIETFEEGEFQGLNELTDLYLHGNRITTLGNEVHGLVQLQYLVVSSNRIRTLRKEQMPEKLKYLYLADNPFHCDCKLLPFLQHLNSTDNPRTDVPLCTPPNDTSLAPPHSSCPAGAANRSSAAETNSTSMVIFLTRHSENNPIFSESRPFVIQDEIAGLDLTNNSLQSMEEARLPERMRHLLLANNKFRLPPRLCCVLPNGARQSHSVKQPLELRLWYPSASRSGFSPKLISHLILSHDSFSVKILEILRKIAICCHNVKLATLFTIRGIPHIVQDANITKCGPDDPESPGLADKTIWSLTDIDLCPRILASMFQSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VIZ8</accession>
    <name>A0AAV4VIZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_594251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014542">
        <property type="protein sequence ID" value="GIY69498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VIZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9978" checksum="33FD5D6F173458C9" modified="2024-11-27" version="1">MQRPTQKLNGAKNTCNSFLGRQITNISPHKTAQRKRYLRKSVSPRLDFGIEKPNTKLKKDSTSAQHVLSTMEMFIERLLEKTFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VL72</accession>
    <name>A0AAV4VL72_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_579711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014752">
        <property type="protein sequence ID" value="GIY71072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VL72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="14318" checksum="E36EBD0216E6E0B3" modified="2024-11-27" version="1">MYTSLGLALGMVDLTLTHVVECILTFVYCVISIICLITSLSDVPAAMRKASATFQNIYNKEILKDEFLKLDPSGFQCIVAIKALSNLNPVYITAWDMLKVDKNLLLNNFGCILTFGILFIQLQRTAYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VM75</accession>
    <name>A0AAV4VM75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_108571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014758">
        <property type="protein sequence ID" value="GIY71143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VM75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14652" checksum="D5ED49750E6CFCDA" modified="2024-11-27" version="1">MPTKSQAQKLKKKKTEHFVTKGNINFSTQQTTLFRVFNGESGRDSSASFESRKFAFSGFTNAVLNDNLLFRHFYDLRNGRTVVGNEKLRLRVSTIFNDPAVTETSILLPSGFCCNQEVCSSNRIMRESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VS09</accession>
    <name>A0AAV4VS09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Down syndrome cell adhesion molecule-like protein 1 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DSCAML1</name>
        <name evidence="7" type="ORF">CEXT_5071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015052">
        <property type="protein sequence ID" value="GIY73266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VS09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000104">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF6">
        <property type="entry name" value="CONTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="582"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="76"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="172"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="469"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="354"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="686"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY73266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="716" mass="78717" checksum="4044BB0B1C1CD683" modified="2024-11-27" version="1">MGNIQVTDIGNYTCVASNAFGRDSKTESVLIEGYQNETPVLHPLSMPPDLGIGDSLDIVCSLKRGNIPVTFDWKFPHWTKEPMDTTAAKGSGLIVDCTSTGHPTPRVSWNRQKGTEHRENIRSEGQWSTASNGSLIFSRIDESDAGVYVCEAHNGIGPGISKSIQISVHAPPELKKKFERVTVRRGHTARLMCEITGDQPLHVSWKKDNQDVNIQFGTRFEVVKDTTDYGSKSELLIHDSQKADVGSYVCHAQQVRKRRRESEINSPGASVSPGHPHLRGAGAIDPIVLATLLLGRRARRELRRQILEERRWVQTSVKKGQITSGDSSRRADVRHHSEPAPGHLVQRAGVRQNWRGAGGPLHAHHLQDGRGRSKSRARQLESHKSIMETASKTSLERPSARLLRWEQSGPFEFTLHLPDRGDDGPPRGSLLIQGLMKATTYTIVVKAFNAAGSGPPTHELQVTTLEEDPPSPPIVGVADVTASSVGIHWNIGSDKQPSVVQYLLEFREEGEEWDHIHLPGERNSFYLTGLKGSTRYELRIAAYNVFGRGEFSPTIDFTTGLAEISVPFSTTHSNTPFYFRPYFVIPVAASVVVIVTTVVIAWVCYKRMTLRQDRLLAACQPLDCRLMQARVPLQRGDTVGGYCDPVARPPSYTPPMGGRHPVGVPDDDDAYDAPWDMANPAGVPGNAQAGSYTRLKSQMPNPGGAIVIGHQSGSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VS27</accession>
    <name>A0AAV4VS27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_38611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015044">
        <property type="protein sequence ID" value="GIY73207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VS27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14715" checksum="34FD968F53B1D340" modified="2024-11-27" version="1">MVQNKVCWHGFGVVVANIMDKESSGAKCTGLIRDPNQSSTIDDRRCLSGSPLRTSNKMVTTINSLIYIHLCVSNHNTEEMENKHEGAGAPFSPSRRRRRKKSLNMKYYAQIRFKGRGFFAYENWDNVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUH6</accession>
    <name>A0AAV4VUH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_745121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015103">
        <property type="protein sequence ID" value="GIY73584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14570" checksum="F0C8A0CD2510E2D7" modified="2024-11-27" version="1">MVTSFENSRLYQPNCCCCQPSPKIKWENAHHLRDVAQINEQKQKRNCVRGISVGIFCLRIEDFIEKQEQISGLPGFFVEISHHASLHRHKRTFFPNSKDCTSSISGNCFRKRVEKFIVLVDLLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5U6</accession>
    <name>A0AAV4W5U6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_782921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015627">
        <property type="protein sequence ID" value="GIY77450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="10203" checksum="36CBA5D9A5E1C570" modified="2024-11-27" version="1">MNRNRKRSSKYPKKEEEKSINWNFIYKYQKILQLLCEAMDSPGGGLFRFPTHNWNCIRFIRRDRIKSEGIVFWDLSGMSSLQISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGN4</accession>
    <name>A0AAV4WGN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_460161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016050">
        <property type="protein sequence ID" value="GIY80748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10297" checksum="10AB68294574D58A" modified="2024-11-27" version="1">MVCLFEVQTKKNIRNPSKGGEYHYGLTKCQGYSRQVEKGSCPRIPSPRIYAIPHSSLLLTLIYNVCSIDVLWKVRTFYSSSFESKRMIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJS0</accession>
    <name>A0AAV4WJS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lig_chan-Glu_bd domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">AVEN_226767_1</name>
        <name evidence="12" type="ORF">CEXT_530681</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016224">
        <property type="protein sequence ID" value="GIY82231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="11">
        <location>
            <begin position="16"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY82231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14912" checksum="C3ECC0A5EA91F2BA" modified="2024-11-27" version="1">MNFPRFIRIAVLPYRHVIEIKDGNRIVGGLEAKIINLLSNVLGFRYQIFISKEMAWGHPLENGTWTGLIGMVSRNESDLGFGFTAVTKADPKPLTSFLTTLKRTHSLPDYLPFYPQRVLWPILSSGKCGCSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WP89</accession>
    <name>A0AAV4WP89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pol_846</name>
        <name evidence="2" type="ORF">CEXT_537781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016465">
        <property type="protein sequence ID" value="GIY84069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WP89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF2">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="40"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="20855" checksum="7CC381564CD76547" modified="2024-11-27" version="1">MYPGGTAIFIKKHIPHHHIPTPDLSTTQATIIQLHTKTPITIISTYVPPQRNSATDPNRNFFPINDFNLLHNRFNNYFLGGDLNSHHRKWNCSRANSFGINLYKFTNDNRLHIAAPPTPTRYGTNTPSTIDIALFKNLNYRYTCESVSALTSDHNPVIYHLDLTIPNIDSQNYMIPAGSSLHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSW4</accession>
    <name>A0AAV4WSW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_534741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016592">
        <property type="protein sequence ID" value="GIY84914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8505" checksum="75D0BB1D6C30469E" modified="2024-11-27" version="1">MRTQWKGSGSQFQRISRIRLEKGSLWGHKKTGSGYPWSSIVLAERVDSVCRKEQCVFLKGTRLMQIVNKYIQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUQ0</accession>
    <name>A0AAV4WUQ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016635">
        <property type="protein sequence ID" value="GIY85263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUQ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16106" checksum="2C49F9DB6278C4B2" modified="2024-11-27" version="1">MDFWPLEGHKSTAVSSAEAINPRQNTPVSNFATVNNWAINLSSISVEAVIHFVSHNVTRSYSDAISDSRSASGIILGLQKWLMDTRIHGRFHFKTSFSHLPLRCLQSVDRSTLCGLRQCSCYRKLYSLQVGGGIDHNEPINHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZ01</accession>
    <name>A0AAV4WZ01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_470831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016865">
        <property type="protein sequence ID" value="GIY86984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZ01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9202" checksum="34E1982F2D5511C0" modified="2024-11-27" version="1">MTTSGRHRSIYKEDGHQLPPTTQNPLCHQNRSLKSPCGKKQGYHLSAPFCLVLDALGFISPGCCDYKERLTLRQIIVHPPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3M7</accession>
    <name>A0AAV4X3M7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_707651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017158">
        <property type="protein sequence ID" value="GIY89124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10940" checksum="6FBB6A7F4B8192DD" modified="2024-11-27" version="1">MEGALGLLLEKPGLTWQAKRNKSRAYPRDGIIKYGCGFWHEKYVGSAWFRFTPNPDCITGLLHCTSAEFENFVCFSTFIRPMEGYSDLFLSFSTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X495</accession>
    <name>A0AAV4X495_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_695021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017217">
        <property type="protein sequence ID" value="GIY89503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X495"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="11152" checksum="FAD44F102E6E897C" modified="2024-11-27" version="1">MVTDGFWLVYWVGWMESRCQREKIPSEERRIKREKLRVRKSRRTEGKKRKKRKIADGLLLREDRRLDAFENAEQKERRRKGKLQMAHLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X513</accession>
    <name>A0AAV4X513_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017115">
        <property type="protein sequence ID" value="GIY88878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X513"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15249" checksum="52F11B4953E31174" modified="2024-11-27" version="1">MTLSFHSSRLLTSMILKHKFKSETMEASKSENRAILNVGTICAPDVPRKAAVTRHIVRYLVQYRFHYLGIPPSSERYMDITGIESFAPIPPPINDPWQKSKAAILLAERHAGMALGLMKPGASLEIRFLRQMVLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAB5</accession>
    <name>A0AAV4XAB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_455071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000113">
        <property type="protein sequence ID" value="GIY92211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9278" checksum="FA68D5326C72595A" modified="2024-11-27" version="1">MRSMHQLNLSVEVDSLTEMQQFAALVISDRVDKSLLSVFADKIMCLLYSSRKAKKTMRSPGNGIKNSVVDIDSGWILFISVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDE8</accession>
    <name>A0AAV4XDE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_141851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000079">
        <property type="protein sequence ID" value="GIY92009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11728" checksum="2080F578A4FD8F38" modified="2024-11-27" version="1">MRGRRCSCLCFQSFHVGFVFGASKIAKLHGSHLPQADDDDLPAPRLLHPLLSQANSENVLSQPQCISYELCCNLVCSGTAAAPLSMSARTQELKVALFKQALLLFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEA5</accession>
    <name>A0AAV4XEA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_60781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017523">
        <property type="protein sequence ID" value="GIY92340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14677" checksum="A25CCC54886D5537" modified="2024-11-27" version="1">MYNDTYFILVGGAPERDELKYGERNVKRCEVQISRKVTCNVLHCNLKLDLPVIIKTFSSAVRKRRNKDESRGLGEGRAMTLKLNGRNEVRRTRDNFFRSSFFIAGKTSAERKKSKNKNFAICEKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFV9</accession>
    <name>A0AAV4XFV9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_781661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017727">
        <property type="protein sequence ID" value="GIY93972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10546" checksum="EF25F33A1076244C" modified="2024-11-27" version="1">MIAFIAISVISLPLRARDPTYRRRPPIKVRVIPAAEDTKQRERMRAPDSVSLSAFFLTSRQMGIKHSRERLSGYKWKLWTGRSSVFIGSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGP2</accession>
    <name>A0AAV4XGP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_563881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017767">
        <property type="protein sequence ID" value="GIY94302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12472" checksum="69D26D8B8E3B1EDD" modified="2024-11-27" version="1">MPVFFRSTCSLCSTKEICKLSKGHMTHGILSYSNNLEIPVPQKMNSRYLIRLQSGALLRALPYFGKILFRKRRTTLLNLSSLSRMGNGDCGDLTIFAILHEGLSQQGMFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHN6</accession>
    <name>A0AAV4XHN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane protein 181</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TMEM181</name>
        <name evidence="8" type="ORF">CEXT_46641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017799">
        <property type="protein sequence ID" value="GIY94540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015643">
        <property type="term" value="F:toxic substance binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040416">
        <property type="entry name" value="TMEM181"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047843">
        <property type="entry name" value="WLS-like_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31918">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31918:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06664">
        <property type="entry name" value="WLS-like_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Wntless-like transmembrane" evidence="7">
        <location>
            <begin position="92"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY94540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="357" mass="41592" checksum="0E8C6E71662B99F8" modified="2024-11-27" version="1">MFSEFGKNIAPTYYHDRCEKTGPFLLHSPAVSTFSQQLWVIARIILKNGDDERFNKPFHIAVTIHGVSDMNKIVVVLGEQHNHNRTRELRCFNSCWFAYSFEIFFFFDWSIEQKWISVLLPLLVLYNDPVFPLSFLVNSWVPGLLMLYVSSYIFVCTASILALHIIMVLDRMNEAFTKFYLPKCIIIGSLWLSAFTLASWQKYNEMRDPTYNYKVDTGHFMGFKVFFFTIGSVYLVYLFYLIIRAYTELRSMPYLHIAITVLRFGISVLQDNFVAELSTNYGSSAEFMSFYSLLNFYLVTMAYVYAPPRGAYFETRVKDNPTLSMINDSDEEVIYASDSENRPLNPTRKTPDKEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN75</accession>
    <name>A0AAV4XN75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_575701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000616">
        <property type="protein sequence ID" value="GIY96099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12741" checksum="846CE76F2988B089" modified="2024-11-27" version="1">MTAFVVERKSSKFLTKSRTSLEPEFHRCSPKKVGANEVMGCFAIGSSCIGLGRDHWIEMLDNPETRRAVVHPSGDPLRSDGGHFHHGQILPHQVHQYEMTVREKSISPSASSTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVJ8</accession>
    <name>A0AAV4XVJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_512411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018336">
        <property type="protein sequence ID" value="GIY98777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15433" checksum="047537E760AC2BDC" modified="2024-11-27" version="1">MCQLERANFKTQIWLGVIDHSTWHKKLDAAEMMEHESSVFPQVLVMDARRKENVSVGGAEHESSVFPHILVMEARRKENVSVGARETPEIFLENSENSSSIGIPFYIPSNSEVCLWIRWPTGTAEMHVIFSKVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXX9</accession>
    <name>A0AAV4XXX9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TEP1-F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CD109</name>
        <name evidence="9" type="ORF">CEXT_100941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Binds covalently through a thioester bond to the pathogen surface resulting in pathogen clearance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a TEP1-N chain and an TEP1-C chain non-covalently linked. Forms a complex composed of TEP1-N and TEP1-C heterodimer, LRIM1 and APL1C; the interaction stabilizes TEP1-N and TEP1-C heterodimer, prevents its binding to tissues while circulating in the hemolymph and protects the thioester bond from hydrolysis. Mature TEP1 and to a lesser extent full-length TEP1 interact with SPCLIP1; the interaction is induced by microbial infection.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018325">
        <property type="protein sequence ID" value="GIY98685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1930:FF:000001">
        <property type="entry name" value="CD109 isoform 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF136">
        <property type="entry name" value="CD109 ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0882">Thioester bond</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043439266" description="TEP1-F" evidence="7">
        <location>
            <begin position="25"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Macroglobulin" evidence="8">
        <location>
            <begin position="129"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00057615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00063781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00078071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY98685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="400" mass="46122" checksum="57C7B8C18451EBE9" modified="2024-11-27" version="1">MVYFSSVLAALVFALFCFNTSVLSQRNSPVYTVIAPSKLRPDIVYHVSITVHDAPSPVDFNVQIFGTNEDRIPVSVLKDVHIDPKQTQVVDFELFDWKPGDYTLEVIGQGGLTVRNSTKLIFEHKSYSVYIQTDRPVYKPGQLVQFRVIVTNPYLLPRSSQLPIDLLVKDGHGNSIREWKNVFPTNGVASAEFLLADRPVLGEWAVHVNVEGQKFHKNFTVAEFIMPTYEVHIELPFFILLTINQMHSYGKAVKGEVTLTVAPRTRYNKLNVRPYESFQTKARIDGTVVIYLNLLKDLSLRTDFFKREIEFFALVEEEETGHKYNTTNTMWIYDKDIKIDLIRTSETFKPGLKYTAFLKVSHQDETPVSNSRGQLELLYGYTIREEDWKKNYILFLEMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZS4</accession>
    <name>A0AAV4XZS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_72051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001049">
        <property type="protein sequence ID" value="GIY99466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="10804" checksum="5DFF4A23C32E0003" modified="2024-11-27" version="1">MECEGHNNNKPVLHPSSSKRNIKKKKVYTSFVTKRLLAGCGNDSHFEPSINSSQGLLSISNRNFPASATENTLASGNAANGSEDTAPLDSNMHSKNGRKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3A4</accession>
    <name>A0AAV4Y3A4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_610051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018543">
        <property type="protein sequence ID" value="GIZ00456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3A4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="324" mass="35295" checksum="D9E95AED689C2651" modified="2024-11-27" version="1">MNSTIEALDFLGASNFAASPNSAYSPICHCTRQQSAVKQFTGACDDQEVTNIVRELVSEASCVPPNVSPIVCAETKALDNFEACLTSSFSVCHRTRQQLANREIKSVLGENNFSPVPDDSSHVFQLVENALLEQEVLDSVSDMLNRISPNNSPCELTFDTISPPVVSGTFFQMENILSPIPMCTSPCGITFDGSSPLAKPRTFFQKEEHLHASAEAVPSTETDEVTLFPSDLEVRDLLFEKSPSASFDFVKLTCVRCRLCFSSASGLEHHMKDQHDITILQNKRSESSAPSPPKVCSAPPLELLQVGPCSGPPHCAPFRQHSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4Y5</accession>
    <name>A0AAV4Y4Y5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_749311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018823">
        <property type="protein sequence ID" value="GIZ02521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4Y5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12261" checksum="D7D42A30CF51B1E5" modified="2024-11-27" version="1">MILNTSVDLCAKNGTTQNISCNRKMRFTMKEKKKPSRYQQYDCSKLLTACRLKQKMKANIKGKKHKKGQKEKDKSKEVITVKQGIPVFFEKRNSFVPSPSFVSSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6B9</accession>
    <name>A0AAV4Y6B9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_313351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001492">
        <property type="protein sequence ID" value="GIZ02688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6B9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="232" mass="26193" checksum="5B02AA77379C2C48" modified="2024-11-27" version="1">MRRGSALSRPLTTPERTSRRHAPTPLTETESTSSASINPPTVQKCLPLYNKHGKKIGSQFNGNCVWPSFWLISSLKNETSFLKGVHLDSGVRRSRSKHRKLALRKKLLMTAVDQEGHISSLGRGKESRSEQKDPNEARLGPLRATEHPRKDLHRHAPTPLTETESTSSGSINPRLCRNVYPVDLYFAFILVDLITEKRNFFFQMECTWPAVRRESFEVPEAGVEKNSPDDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y729</accession>
    <name>A0AAV4Y729_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_176701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001420">
        <property type="protein sequence ID" value="GIZ02246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y729"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14274" checksum="B2A8B5AD14D6E72A" modified="2024-11-27" version="1">MQIMFQTMFENSLWATPRRSPHADSLATVDRHALSVPEGKFTTIDGLLEALFRIIVIKMKDPNIASARRHRFYLTHRVFFFILFPCKFHLTLTKAGNFQLKGSYFTVLKPYEQVKVVRKKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCX7</accession>
    <name>A0AAV4YCX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_434131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001691">
        <property type="protein sequence ID" value="GIZ04075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16080" checksum="98E21948B561C691" modified="2024-11-27" version="1">MDTIKISSLQQFGSTPYGQKDGIKKKVSAGVAISTLDSMDILRQRFKRKIYGSQRGVNVYLRNSYKTKKRLHCSNTTSPISPPQSQQTPCKEQQYTKIDEQWLKGLEGTLLQSNPRPFRIFRSFIHGMPAEYHALRKLSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8I6</accession>
    <name>A0AAV4M8I6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome non-ATPase regulatory subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PSMD12</name>
        <name evidence="5" type="ORF">CEXT_198271</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019491">
        <property type="protein sequence ID" value="GIX68447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8I6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000070">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="186"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX68447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="47375" checksum="1A508227F03C8D61" modified="2024-11-27" version="1" fragment="single">GADTHSCGRILVAIVRLCFETKNYPALNEHIILLTKRRSQIKQAVTKMIQECCSYVDQMPDKQTKMEFIDTLRQVTAGKIYVEVERARLTHKLAKMREEEKKIDEASKILQELQVETFGSMDRREKVELILEQMRLCLAVKDYVRCQIISKKISTKFFEDVSTQDLKLKFYRLMIELDQHEGSYLAVCKHFRAVYNTPQIQDNVEKKHVALKKVVMYLVLSPYDNEQSDLIHRVKEDKNLEEMPKYKELLQLFTTPELINWKSLHQKYETDLREATSDVTAAEVFGHDDIGKKCWQDLKNRVVEHNIRIMAKYYTRITLKRMAELLDLNESETEEVLSNLVVNKTVWAKVDRLEGVVSFSQLKDPSEVLNDWSHDLNQLMQLLSKTTHLINKEEMVHKHLLSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCX3</accession>
    <name>A0AAV4MCX3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutS core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_58242</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002094">
        <property type="protein sequence ID" value="GIX69921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="566"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="4">
        <location>
            <begin position="347"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX69921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="586" mass="66188" checksum="3549ABB1A8439BCC" modified="2024-11-27" version="1">MIPMISTTAVGTATDAPASRSQKASDSMASFIEAIGEFGMKALEKPQCARKMFCELAVDNIVADSPVIQKAVHLAALAMEDSWLEQLGVRGIITSLNDGTCNEVDCDYDPEGKQLHRHLRKKGAFFELSYFILLLLNHQNLLSFTRINAMSNSDKKYLSTSDSLRNNTSNSKESNNADFSTEADEDVTSLVALVLLLKQAEPCAIVTSCRTDENILNILKQINNVSRPSESTNISFMSPPLQDKLHLLPGIDFALEACRHRLQNLDLPNMPKNMNDVERKIYFSSLIDFTNMCMVKAAGGLLKFINNSPFGPCLDMESKRVSSISTLTLKNVVHIDENSFRALQIFKKKGTHLCICNKCKSAIGKKELKRWFLLPSNDPTLLKERQAAVKYFISSKNADVMSTLQGSLKHIKFLPRIISRMKTAQASMNDWQSLYKTVYHAMLIGEICRSRSSSLEIFNQISVTFSSDLFRIASLLNKIIDFEEYAKQNHFVVKPGVDSELDKMKRTYNGLPDFMTQVAYQELQDLHPDIQQCSVIYLPQLGYLLAIPATDEMKETKNYSIPNLRFMNWMLFLGIHFVIFMIKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIM1</accession>
    <name>A0AAV4MIM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_124071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019844">
        <property type="protein sequence ID" value="GIX72384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9231" checksum="D2D4C832E4B711A9" modified="2024-11-27" version="1">MVSMIDQLSPPKVQVWTLKQYYLSNSLSFTLKWTQCHRADLMTPVSSCSIRGRGGGERHSQPSIPSKTERANCFLCEAQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNB4</accession>
    <name>A0AAV4MNB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_432911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002446">
        <property type="protein sequence ID" value="GIX73839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9529" checksum="1562652DC6CDEE28" modified="2024-11-27" version="1">MQVKPYPQLFHRLNLKSDNLATERNTSLCLFEKKKKEKRRRRKINRPAERKADQKTVTRSLIKASPYPPTGSQVAHAECPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNF6</accession>
    <name>A0AAV4MNF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_436091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020023">
        <property type="protein sequence ID" value="GIX74077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="11785" checksum="F576F7E8E0A82663" modified="2024-11-27" version="1">MNAPEEKKSSVVGFSPGSTFSLAKDAVKSQCPYFHFTSLHRFTCTPTFPTDHDSYPPYSSHALHLCVCVRTSCDPHCFVLHCGSPGFITGWTALGVSALRATEGLDGGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MP46</accession>
    <name>A0AAV4MP46_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_449921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019977">
        <property type="protein sequence ID" value="GIX73699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MP46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10406" checksum="4D8A119D89634944" modified="2024-11-27" version="1">MFSVKARHANKLGAGAESRSLTAVAPCLRDVTENRDSDSEALPTFIADSVSSYSFKSIPLCTQSVSRRVCCAAANEGIRRILLPRFSFPSDDPTCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWB0</accession>
    <name>A0AAV4MWB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mariner Mos1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">G5I_11571</name>
        <name evidence="3" type="ORF">CEXT_318231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020284">
        <property type="protein sequence ID" value="GIX76822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041426">
        <property type="entry name" value="Mos1_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17906">
        <property type="entry name" value="HTH_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043887338" evidence="1">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Mos1 transposase HTH" evidence="2">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX76822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10123" checksum="69EFE51C51503506" modified="2024-11-27" version="1">MIFLTTLIFCYHLTKSSVELHRMLVESYGELALGKSQYFEWFKNAKVATLSGRNEERGKLPKSLRTANCKHGWMRIKLKCNNISQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZQ6</accession>
    <name>A0AAV4MZQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_650361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020325">
        <property type="protein sequence ID" value="GIX77421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9564" checksum="7FE2F97044418CCC" modified="2024-11-27" version="1">MRKQGPSQPHREAGLTIEGFDYEITHTPGVRMKQADALSRPPDMPSSSQGAEGGTLSASGTKQKRMLSLIKRLPKKVKAQINPHSAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3Z0</accession>
    <name>A0AAV4N3Z0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_764651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002847">
        <property type="protein sequence ID" value="GIX78545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="18454" checksum="8886B44F67180772" modified="2024-11-27" version="1">MGFQISGASKRDNRNLKAHVSTPVVANARPALSIFPAKGRDTYNGRIRSSYGSKPLDPALASPVGVRCHIALRPQYWIEIRLNKLFAGGKVDASSSDSRTPQTGSIYNGEGKRDRLKDFFNATENANLIFETKSCTNGPGMPQEEAKGNEAILKLKSKDSSRIENSSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6C3</accession>
    <name>A0AAV4N6C3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_730151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020589">
        <property type="protein sequence ID" value="GIX80380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6C3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10680" checksum="46C0B68622C738B9" modified="2024-11-27" version="1">MLSKPPLFSSAEKKKKGRKTSLHSLAISRTTFLTRRQLELGGGMEPRDTFARFHSNCSKSRESTPWRKETGKNLLDSGKKFPGVMGLDIIKENTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NI09</accession>
    <name>A0AAV4NI09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_323741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020823">
        <property type="protein sequence ID" value="GIX82947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NI09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8151" checksum="58981F24B8D77842" modified="2024-11-27" version="1">MGRLSICQTTPHAFEVLGKMTSPDRHAIGKNNQLHSAKFEKKKTRVEILEAEESHSSSGGNWQQGNSIVCWDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQZ9</accession>
    <name>A0AAV4NQZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 21A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Ttc21a</name>
        <name evidence="4" type="ORF">CEXT_180441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003661">
        <property type="protein sequence ID" value="GIX87204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056836">
        <property type="entry name" value="ARM_TT21_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040364">
        <property type="entry name" value="TTC21A/TTC21B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699">
        <property type="entry name" value="STI2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25068">
        <property type="entry name" value="ARM_TT21_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B fourth ARM" evidence="3">
        <location>
            <begin position="14"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX87204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="25327" checksum="18789C4A43585367" modified="2024-11-27" version="1">MNKPLSKNPKDSDLASKIGTALAVTYYKAAIKSGGQENLRYDLCSLLCVIKRFKEAEELINTALESGRGVDNLNWLSMESKYLCLLSEVYSKMEMEDQAMSTLQKAWGVQTRVLRKVHMEQADADEHRKKAKQICCQLAVHASRRKEYGSAVQFYSEALTFDESDTEILLALARLKIESHDIDAARQYCATVLSKDSENVPAAVMLADMMFEAGDLQSAKISISKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRX3</accession>
    <name>A0AAV4NRX3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_370771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003604">
        <property type="protein sequence ID" value="GIX86661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050705">
        <property type="entry name" value="Cytochrome_P450_3A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302:SF15">
        <property type="entry name" value="FATTY-ACID PEROXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX86661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="8048" checksum="1F89B2153676382F" modified="2024-11-27" version="1">MPFGSGPRNCVAMRFALVEVKVCLVYVLSHFRIKACPQTKVPLEYRKGSGLLQPLDVTLLMEMRENIPLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSC3</accession>
    <name>A0AAV4NSC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Runt-related transcription factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Runx1_1</name>
        <name evidence="2" type="ORF">CEXT_754541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021263">
        <property type="protein sequence ID" value="GIX87742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="25724" checksum="3B96C7C976786348" modified="2024-11-27" version="1">MLCNPDIKYKSDPGQLRFRQRGPVEPHSAAHYQNYLGHGLQQAAGFAPCPQMDLAPARDSGHATPQTTPTGILPDHHSSSSSQAFPILNDQQPSPSSIKDSLFVTRYNNAMVAASELCLTDRLTELRHGLSGTNPNACSTYPTNHPFNNASLAFLAAGSTPHNPNLPYFALYSSQNQIHSSMQLMNNGDTRSSTEEETVGAQRCLDRPSISEILVPATPYYSPNAAAITVLRMSEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2I2</accession>
    <name>A0AAV4P2I2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dual specificity protein phosphatase CDC14AB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cdc14ab</name>
        <name evidence="2" type="ORF">CEXT_126661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021500">
        <property type="protein sequence ID" value="GIX90426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2I2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17657">
        <property type="entry name" value="CDC14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029260">
        <property type="entry name" value="DSPn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14671">
        <property type="entry name" value="DSPn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dual specificity/tyrosine protein phosphatase N-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="18171" checksum="22C2BD6391EC9253" modified="2024-11-27" version="1">MDELENISLHVAEFIKGRLYFSTLQTPIKPRSTANTHFFSIDSELLYESFYSDFGPLNLAKLYRYCCKLNKKLKILLIIQEEDSSLHYFRSQEKSECCIFDWVICYNLLEKSPVEAYQPLVSNNSPLFIPFRDASFSHCTYNLTLSDCLHAVSKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P404</accession>
    <name>A0AAV4P404_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_234461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021573">
        <property type="protein sequence ID" value="GIX91305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P404"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12118" checksum="59517F85CBB1D0AD" modified="2024-11-27" version="1">MRSPDISGSVPNKGRHPQEDTLKMTTSSPVLGLGVLANFAACRGGGGWLGWIKRRAIHQTPTDYEEEKRGEQVKRRSRKYYLPPAMVEGTDFKMKFGKGKNSQFVIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6E5</accession>
    <name>A0AAV4P6E5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_6824_1</name>
        <name evidence="1" type="ORF">CEXT_593141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004107">
        <property type="protein sequence ID" value="GIX92224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21505" checksum="A2DA3A32A464B479" modified="2024-11-27" version="1">MEEREATRGVAGGTVSSKAKWKWQAESVFCLFKIILFKIPEHFRNPKCKRLDFPGTRPGATYSRNCDLMYSLTMTLSSEAYYIYCLMCVKLMCVFPGGLFDTEDDEQELAFRIAVDRINADTSVLSRSRLVAQVEKIAVDDSFRATKKFKPGVPESPCEESPFSKTMPLQKMLRHRPTSFEPINKYCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P779</accession>
    <name>A0AAV4P779_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_770241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004117">
        <property type="protein sequence ID" value="GIX92348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P779"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10927" checksum="D2C5A2329604BB5B" modified="2024-11-27" version="1">MRLNTIVPIEKQLQTTLRRTVYETQYPHIASIKWVDAISIFPNRSPEQKKSSIGGFMDAMQMRAPRRMTKRCRHDVFRQHNRQFRCCQTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNH4</accession>
    <name>A0AAV4PNH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_33521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005007">
        <property type="protein sequence ID" value="GIX99107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11835" checksum="EB7CCAA1B1E5F4DB" modified="2024-11-27" version="1">MWCGVIVVGTTFRKVNGDSVLYFATRWRFQSVYKRQLIIFYDLEFFYPTDFLLSASTCASESLKVAETVLAGIPGTSYTEKNQTILIKLIEMMAGEVAVVNKVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWE1</accession>
    <name>A0AAV4PWE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_220341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005364">
        <property type="protein sequence ID" value="GIY01738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19534" checksum="D32AECFA30734522" modified="2024-11-27" version="1">MRYGDLADILAYCPKLETFGNIEVFSILSKMSDSEILLPPYQLRKCFLNRNSPPVRNLNPSHDCVEDMEDIENQDERRDVAIVASACPNIEQLHVQMSQEHFSDIFSRLSLFENLNFLEIESVHFQSRFQSELNFLTELGSRLRHLAIYGINCVNLYSVLTFVQNWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZU8</accession>
    <name>A0AAV4PZU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_205241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005316">
        <property type="protein sequence ID" value="GIY01406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13366" checksum="A0965A0B33637EDD" modified="2024-11-27" version="1">MLKQYKTLQQNQKQKLSRVDPPVMSASCGTGFCSTDRKSLSMILAILTSAKKKVIHNTEQERKWPLRRSDMWLWVSQTRSELSDDVTRACSHGRLRYRVQSGEQGDENLKMRCDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0F8</accession>
    <name>A0AAV4Q0F8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_14267</name>
        <name evidence="1" type="ORF">CEXT_526471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005401">
        <property type="protein sequence ID" value="GIY02016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0F8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11702" checksum="B30DF9C51C08DD00" modified="2024-11-27" version="1">MPFVRIDDKQLASEYGFDTDIPVLVYFEKRIPSVFKVNIQLSFQDSADLTNEQQVWKWLHLQLTSDGIEEVTEKFSSTWLLIMTLLLFYFTTTNQKKEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1Z2</accession>
    <name>A0AAV4Q1Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_758191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005415">
        <property type="protein sequence ID" value="GIY02141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9857" checksum="AFCB26DDA6DB0A8F" modified="2024-11-27" version="1">MNANEKLVRISEKDQSFQNRSPRQLECIHLEQSGEWLNMQLAIKHSAVTVERARGLRCDFWDTRVSSGICAKSRKFSFAQRRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3V9</accession>
    <name>A0AAV4Q3V9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_84854_1</name>
        <name evidence="2" type="ORF">CEXT_8221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005644">
        <property type="protein sequence ID" value="GIY03967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3V9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="20643" checksum="B2325BA89D6F99BF" modified="2024-11-27" version="1">MQDLYDDILIQLNKDDSTEEMKKLLGVYENLATTIRSFDESFSFPAFLATLLNLFGLFWTGYRIAFLTNIHDHSFYLICPFIFHLCEHLLLMISATVTNEKTAKATFIMQCLLRHCHLKTRMKIKYEKNIGSESNLTLWKIYVFDRSLLITSFGCLLTYGILLGTLGRGIVKLHKKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6V0</accession>
    <name>A0AAV4Q6V0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_145421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005673">
        <property type="protein sequence ID" value="GIY04131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6V0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY04131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="45375" checksum="F3223FDE8B2A67E0" modified="2024-11-27" version="1">MSLIALTQPTELEPSTPKQKKKKKGTATNWIPMFQNTPRSTDGAIPRWQDLFASRRPTSCSTSTSIKFRKLDAINHGIILMVGIGILFFLCVTEIIFQLSSSISLTSYLPTNSAINFYEVTLLIVPLFLKTNVLNCLTQNLKPSISQTKETKKEGTSTNRIPMFQNTPRSHRRCHTQMTGSICHSKANIMLNFHKYQVQEVRCNQSRNALIVGTGILFFCTVNALPSPQNLNLPSPKQKKEKKEGTATNRIPMLQNTPDPPMAPFPDARIHLPLGGRHLAQLPQVSSPGNHISFVIINIFHVLPPHNVAINFHDATLLIVPLFLKTNVLNCPDTELEPSISKTKRRKKEGTATNRIPMFQNTPRSHRRRHSQMPIRRSDSFATRPTSCSTSTSIKFTKLDAINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7R6</accession>
    <name>A0AAV4Q7R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamate synthase, amyloplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_145461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005673">
        <property type="protein sequence ID" value="GIY04136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate synthase central-N" evidence="1">
        <location>
            <begin position="71"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="560" mass="62758" checksum="85F0209306294E39" modified="2024-11-27" version="1">MLLVDTQAKVFIKDEDLKLQIARKRPLEKWLNEMFTLDDLHAAGFAAGHHSSHPKLDQSNRTTSQAVEDRRLALFAYTIETINMLIVPMVDTQKEALGSMGNDAPLACLSQYQPLIYDYFKQLFAQVTNPPIDPFREKIVMSLACPIGPAANILEPSAQQCCRLYLEQPILSLKDMEALKATTYKGWKTKVIDIVYPVHEAAEGLLPALNKIREEACSAAENGYSLVILSDRKAGRDYIPVSALLALGATHHHLINKLQRMKVGLILETGEAREVHHMCVLLGYGADAICPYLVFESMAELQGEGVISESLTEDMIFKNYVEAVERGIAKVMAKMGISTLQSYKGAQIFEAVGLSDEVVDFCFKNTASRIGGVTFRVLAEENHERYRIAYSDRDCDNMVLRNPGNYHWRSGGEKHINDPLAIASLQDAARTNNKNAYEKFVEATMENVRACTLRGQFELIKVPKPIDISEVEEAKEIVRRFATVLITRSNSFCVCVRCNSFVNFTWLMIQEPAVQSNYCLQITVCHCLLLKRRAYTICVIAVCPRGRSHPKGFGRINPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8P0</accession>
    <name>A0AAV4Q8P0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DEK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_354191</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005836">
        <property type="protein sequence ID" value="GIY05386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8P0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000779">
        <property type="term" value="P:regulation of double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044198">
        <property type="entry name" value="DEK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468">
        <property type="entry name" value="DEK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468:SF1">
        <property type="entry name" value="PROTEIN DEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="6">
        <location>
            <begin position="174"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="7">
        <location>
            <begin position="354"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY05386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="45852" checksum="7CB6802CEC05B11F" modified="2024-11-27" version="1">MSDTKDESNSTTSDVKEEESSPKTEEAKSVDESSKDSEKDSIKDENVKEESGKEGSEKDGSSDKESSDDEDALFDRPVEQVGCRARKQVERLEISFNTPKEKHEIKAGKGQKLGECPRIEHQIQKTSIEDLKPVHKILFGRVGSASQIKKSIRKFSGFPFGKSSSEFKRKRAFAEKLTANVLKRICEVLDLERSGSKEEIIKRILGFLLEPKDSGKKVKSKNKGSTKDKGKNSEKKPKSIKKPKAKKASSDEETSINDSASEKEDEEEEQDEQVDDDDDSDYDAKKKAKKNPKAKKTPPKTVAKQSDKKGKAKKEEKKSTGKGTKRKREDDDDSASDTETDSSDEEPIAKKRKMPSDEEIKKLVKKILDAADLQQITMKKVIKQIADAYPDCDLSHKKAFIKSTVKSVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFT3</accession>
    <name>A0AAV4QFT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_251321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006011">
        <property type="protein sequence ID" value="GIY06890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8263" checksum="F1121E18C25F1929" modified="2024-11-27" version="1">MGEVLVRVLDPMSSSRELFVRVIRFIYVDNFIYEIVVEFQSPQIAQSHVVSHVELLDETVVQSGCGLPCPPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRQ4</accession>
    <name>A0AAV4QRQ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LolA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_05627</name>
        <name evidence="4" type="ORF">CEXT_730571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006502">
        <property type="protein sequence ID" value="GIY10278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058831">
        <property type="entry name" value="LolA-like_dom_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902:SF1">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25898">
        <property type="entry name" value="LolA_2nd_metazoa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="LolA-like" evidence="3">
        <location>
            <begin position="77"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY10278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="542" mass="61833" checksum="BE15F518E86907FE" modified="2024-11-27" version="1">MFFFCLPADQWVYSSGGTAMQDVVSAGDGMLPVPAKVSSFGTVYDEVSKERNAFNKTESIFWFKGQPDFALETFRIPPYMYCEDFRGRKDMPQFPDAFSTRVQKTVVQRDTLGNLATSEVTSFEQIYYYKDKALARRDFTPDPDLDVDIINKFLSKDPIRSVYDFNTGVMYLTSIPTGRCYYRPIIPGDFFDASKQHMYIKMADPAEIFRMEHDKMEYKGNDFSRDIECDVFAGKYFDEHYNATFIKETYISTNGWHEEADELLEYGVPVKHTILTEELSWQLVDNVTTYHFLKFKAKAPVLRIFDVSNCIETINHKDYAIMLTVSTSERSTIFKYKTQFLESAQWYLAEITAVFTPLRIQRLQLRQVSLASSDTSTLLAFTLVDKPRLKTQTPVGQPGSTFQEALSRLQHFIDRNQFALKFTAPQEIEPITVKALKGSLYVHTADGDLQAPEPIETEETDPEDEVTPSLLQADEEAEGSGRPMMSNGSLALLAFAMLFIGIGIGIAIMYLYLRRVNENKLEDRITLTPQTSTTEPDPLPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSU2</accession>
    <name>A0AAV4QSU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_216611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006841">
        <property type="protein sequence ID" value="GIY12718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11914" checksum="EF5BF6D0C8840A6E" modified="2024-11-27" version="1">MSSKPDSNPLKMNSKIKGEDLIAAVKAQDTAKLVEYASENKSKKQQAKIIISFTTKGSPNKSKSSPSKKVCMEVSRIIQASIDIAFAMLDNNLTLPQDLLHMLVFFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYL4</accession>
    <name>A0AAV4QYL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_83891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007139">
        <property type="protein sequence ID" value="GIY14743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9664" checksum="0AC5E09A51F07588" modified="2024-11-27" version="1">MVEEDKAVTSVDFAEDDSVQPLSGGGDARNQVLFPPFRSAVPIEGPNGHHKSRRPFWGRRGPVGSTSGAVIYSVCEMHMQSGMAFLCNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4R8</accession>
    <name>A0AAV4R4R8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U5 small nuclear ribonucleoprotein 200 kDa helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ascc3</name>
        <name evidence="9" type="ORF">CEXT_308931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007405">
        <property type="protein sequence ID" value="GIY16725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18020">
        <property type="entry name" value="DEXHc_ASCC3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058856">
        <property type="entry name" value="ASCC3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041094">
        <property type="entry name" value="Brr2_helicase_PWI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF13">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26582">
        <property type="entry name" value="ASCC3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18149">
        <property type="entry name" value="Helicase_PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="463"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="711"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY16725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="902" mass="103001" checksum="E4CBF9841E5A42BF" modified="2024-11-27" version="1">MFKFKEQPRLTNFLRVYSEVAAPWSGNTSYDPEELIKKRKELSEKQAKACSIENVKEYLTKNCTCPSSEISNIIKELMSLAKEIAGSDSSTSIIEGSIVFLIDLFRDCRMIGNKEKLKLRRQFGEYPTSAVTKVFGVVKKIIEILNSEIQDDFIEKGFPKNGDELMTEEFGLKIKFNDQSPPDDSFYRIPVKEVHDEDEDVFKKLTFKFEPAPKEEIIDEPIVPKQIITRQKFDQQWLEQELRKTSPENISSTELALTVTQLLKSKSNEEVQNELFDLLGFDSIDLIQNILNHRDEILAVKIMDSNSRDFSDKSEKRPVCMSQVVVQSETEKLLSKQIRKDEKRIQREQAKIPEEENQMIFNPQRFKQLREEALIDARNKPIFYHPSPQPSIDMSHFYPNLCLPPDHKRDNNNIFEEIQIPARKPAGEVLKVERVLISSLDKVGQLAFPDTKCLNLIQSKVFEIAYRTNHNMLVCAPTGAGKTNVAMLTVLREIKNNIVNGVLEKNKFKIVYVAPMKALAAEMVRNFGSRLKALNIQVKELTGDMQLTKTEIMQTQMLVTTPEKWDVVTRKATGDVALSQLVKLLIIDEVHLLDGDRGPVLEALVARTLRQVETSQSMIRIIGLSATLPNYIDVSSFLRVNPMVGLFFFDDRFRPVPLATTYIGVKAPNPLQQMKDMDEICYDKVARQLIDKNQVMVFVHARNATVRTATIIKELALKKNELHLFTEAQNTSEFGSARTVMLKSRNKQLRELFENGIAIHHAGMLRSDRNLVERYFREGLIKVLVCTSTLAWGVNLPARAVIIKGTEVYDSKQGAMVDLNVLDVMQIFGRAGRPQYDSRGEGTIITAHDRLGHYLSILTRQHQIESKFEDKIADNLNAEVALGTVTNKNKRMIIYCMNIKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5T9</accession>
    <name>A0AAV4R5T9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_331801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007459">
        <property type="protein sequence ID" value="GIY17070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5T9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11177" checksum="47C7CAC350883882" modified="2024-11-27" version="1">MRLPQGRNLFIKVNLNISNLTCRNPFPLACRSLPHPTSTTTALNCETPGRRRTMRRGPVLCYDRCDSEKNSSSPFSIDCSGNRARAPQATSDRDSQPQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R609</accession>
    <name>A0AAV4R609_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger and BTB domain-containing protein 47</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ZBTB47_1</name>
        <name evidence="4" type="ORF">CEXT_464481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007328">
        <property type="protein sequence ID" value="GIY16071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R609"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY16071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="24615" checksum="84CFE5CBA374CD08" modified="2024-11-27" version="1">MSTFRVVSRIIPTCAQAQNIRNLMVAQDIDTPARTEWSCTGDRKTGNYVVTQTTFCKEKFHPPNTDLDKVLAAECEAIPGLVNLKKSKLHLTKECKDAKNEESQPEPIIKVTPYVLNDGSCEEPLSEEKPDKKSEAAKVRKPKPARTRKKEPKKTSKSKSKKTPKQKIWKCCGKEFTDPLLYCYHQECHPSNCFECDVCFKEFSGKRALKNHKKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7S4</accession>
    <name>A0AAV4R7S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_580141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007616">
        <property type="protein sequence ID" value="GIY18368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13494" checksum="3655D36F57F92831" modified="2024-11-27" version="1">MKEASLTTSARGPRQGRDDNCHKHLSPVPLEDVGDTDPSSPQSCQSGDGSWPPLSRSRRNPVDRDGGMFPIFTQSRMTTTDKKSRFKEVDLVEDDPIRSDSRTMTLGRPAFNARYHCSDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBZ2</accession>
    <name>A0AAV4RBZ2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007797">
        <property type="protein sequence ID" value="GIY19808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="24136" checksum="2FD596C1A47F1646" modified="2024-11-27" version="1">MAKFSFTGSKPMWATPVMKKLINMQSLSPIDAAINFDPPFIKRLIKKELTAEWQNRWNSSSKGREAFELFPEVKASRIQGDFFLNQLMELWQLFRCFGQAPSCHCGHPTEDRNHIIYDCPMWEDIRKEFFPSNYKSSSIDLILFNKKTKLVLREISGPPARAKYTVGWPARMHCVMGQVILEYWVGLVLRHRSLVSPGSSLYSFALIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUS8</accession>
    <name>A0AAV4RUS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_232991_1</name>
        <name evidence="1" type="ORF">CEXT_427921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008622">
        <property type="protein sequence ID" value="GIY26078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038602">
        <property type="entry name" value="Mite_allergen_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020234">
        <property type="entry name" value="Mite_allergen_group-7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16984">
        <property type="entry name" value="Grp7_allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="28556" checksum="E7B16CF5DB167130" modified="2024-11-27" version="1">MGWDVCSFGHVTFDFNTTSHSWFRKRYVERRELNKSLLKVINKHLMKLPITSIIPGSSANEYVDQILTNVQTYVRDHQLDPMKLPDFQSNFSKIMYVNFNGEAKMFDGWLAGISTIHRTDECELNTTRTTISVSAHLGLKNLKLAYKGHAKFMSWGPTLICGGSVKKVAFYFKIEQTNKKGAKPDLKEFEIVELSTIWIELSGLGPLTWILKWLLTGISKLVEDFIIEKLTTEISSYMEAEFQKLSFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZR3</accession>
    <name>A0AAV4RZR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_184181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008786">
        <property type="protein sequence ID" value="GIY27184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="276" mass="30348" checksum="EAD4BBD4AC2F0AFD" modified="2024-11-27" version="1">MEQYPNTTIPEREPTFKSESCNSSLYLSPFSLAGSVNPEAVNAGWALPSTVWFSRLDDPLLQWVGLLPALHASVLCIWGRGWCSGEKHSGVGGREVVSRAKSAYPDSLILELSGYTEGGLDSWLGFCRHQHLVIGIVEGSPPRWFTTLFQLNSERTPPTVVSKGSMPSFSFFKPTEKTYWTQVLRRTFCQAKGVSGCIWVKIIKGPVVLIECFYRPPFITPPKPLGGVISHGQHAKIVPFSLVLSAASSRTCFAVFTRGTPPPPYHPSLNSKSTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0U7</accession>
    <name>A0AAV4S0U7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Titin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ttn_1</name>
        <name evidence="3" type="ORF">CEXT_728991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008754">
        <property type="protein sequence ID" value="GIY26984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0U7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050964">
        <property type="entry name" value="Striated_Muscle_Regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817:SF73">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY26984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="20274" checksum="627386F08DCBE5C1" modified="2024-11-27" version="1">MRESVQCSVMYGDPPFVFTWYKDNQKLIENQGLTTRKFDEFTSTLVISKVNADSNGNYTCRVSNSAGFDEQSAVLSVKESENHSKTIEFEMKERDIRKNKSFPLSGELDVGMRASVQCAVIYGDPPFQIWDSKNKSFHFPGELDVGMRTTILCAVIYGDPPLIFLGRKMARYWQENAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1P2</accession>
    <name>A0AAV4S1P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_781931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008774">
        <property type="protein sequence ID" value="GIY27106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY27106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13046" checksum="667E4C7C57075DD0" modified="2024-11-27" version="1">MASAQHRHRGCHRVARHPSRPATSCGVAHHQQSRHRSPPLIAASYPCGHIILSGFCVHIFLFMRLCWYLLQKIKPYCATLKRLQRLARQWPALEFVGKIFIYSELQILLSAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3L9</accession>
    <name>A0AAV4S3L9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_16761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008921">
        <property type="protein sequence ID" value="GIY28240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10010" checksum="79C2C86C5699ABAF" modified="2024-11-27" version="1">MHHKHPCVHQQLIHQTTSLSVATTCPPTISLLATTAYPPQTSLRASAAYPPNNILACNNNLSTKNILVVTNCLSTTNILACISSLSTKQHLCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SB48</accession>
    <name>A0AAV4SB48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_167511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009186">
        <property type="protein sequence ID" value="GIY30189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SB48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="57" mass="6451" checksum="7ACC0B67B1AB3BC4" modified="2024-11-27" version="1" fragment="single">CHRKLITVPEGPSRQCVYALSLTFNSICDTLHPARGAEWCNGQWRISPGFTVMQMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SEA2</accession>
    <name>A0AAV4SEA2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_408421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009388">
        <property type="protein sequence ID" value="GIY31531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SEA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12810" checksum="EFA53FCC2A7E0D75" modified="2024-11-27" version="1">MKLIKNYLEKNDSASHTEHISSFHGKSWLLWAFHTSLPKPPLFLIRRADLATFRIVLTQQPYPELTRFAVQKFSSSVSFGQERLELRVLLPTAPIQKAACKLLNNIIKFET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHU3</accession>
    <name>A0AAV4SHU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Notchless protein homolog 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NLE1</name>
        <name evidence="6" type="ORF">CEXT_693181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009654">
        <property type="protein sequence ID" value="GIY33529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY33529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12797" checksum="4AD3C7B8C3125E8D" modified="2024-11-27" version="1">MGQELAVLAIKRYESATRGRPEIMVSGSDDFSMMLWSPEKDSKCIARMTGHHNLINDVKFSPDMRFIATESFDKSIKLWNGKTGKFMLWIGVQMDKRVASGGKDNVIKMWHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJ55</accession>
    <name>A0AAV4SJ55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_380561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009606">
        <property type="protein sequence ID" value="GIY33241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJ55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9604" checksum="0B477490BA57868F" modified="2024-11-27" version="1">MIFLVPKLSESFVDHLSFGWESKLIRFSSTGRYEIPNFIANQPIALQLNHSSLKGTLSCNEAQCFTATEPPHIAAATIPGTSRKRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SM57</accession>
    <name>A0AAV4SM57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_524161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009635">
        <property type="protein sequence ID" value="GIY33407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SM57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043708270" evidence="1">
        <location>
            <begin position="18"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12694" checksum="0EA3FF96C5843EFE" modified="2024-11-27" version="1">MFIYALLILVVWGGAIATDYNCEEGFGGGVKCRNLSEVGFFEFPQSEADIDRMCPRALRFLECLKEFEDECGAERIALHNYSRRKVEALIDLINDICQERFTTSYQFGCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SU07</accession>
    <name>A0AAV4SU07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_27238_1</name>
        <name evidence="1" type="ORF">CEXT_272491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010105">
        <property type="protein sequence ID" value="GIY36892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SU07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12396" checksum="C6EA02713FF9A30E" modified="2024-11-27" version="1">MTPSWRLGGWILQLNEQIVLFIANAQKPQLLCLHFESVFADTSSFTNSRGSTFISVIGVKHLPRKEGWGNHFPPQNVRCARLGSKLQGVEAILESRNEIEIPSSFHVHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUN1</accession>
    <name>A0AAV4SUN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_793391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010113">
        <property type="protein sequence ID" value="GIY36989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY36989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="21525" checksum="2B5A519D998EC560" modified="2024-11-27" version="1">MERYLFNKHLPPNGEERSLQYLSCPRPIKRGPFPVEIFTSCEVRFCLSTRVLFSPPISFFICILCARLDALLHRQIKESTRSAGERLHIAINLTPEREKDLAKYRRAREKKRRKPPRIKHQKEESVKKRKATTPPAREREKSITSQQAEKKKSNHVCVCVWWHACVGAWIGFCGVTALTPTLLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY20</accession>
    <name>A0AAV4SY20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_521691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010057">
        <property type="protein sequence ID" value="GIY36498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10480" checksum="0DB9F37D980EEE57" modified="2024-11-27" version="1">MAHRGHATELLKSQPYPCQGAVLQGWSPLARMSFALRYSGATNDFPPESSGLTGFAIISLAAALLLLSLMPVNDSLVMTEDVGCPTYVTIGIFVTVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYY4</accession>
    <name>A0AAV4SYY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_449251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010332">
        <property type="protein sequence ID" value="GIY38617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11753" checksum="0B013BFDED91BEB3" modified="2024-11-27" version="1">MRAAEKSYLIFSSSPLIFDGDSLPNYFTGEKLSKNIDTLSQLGTRGQCTPSQKRPDPPSRGGDATWQTRLTAMTVAVELMGLHRLLRRQFVPRPNNALRLARTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZF6</accession>
    <name>A0AAV4SZF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_491361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010219">
        <property type="protein sequence ID" value="GIY37812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10201" checksum="804F0A9A8125BF08" modified="2024-11-27" version="1">MRLINLPSHPTYSTLQKTYFRHHDTDPNINENHEGKGRDNDFGSSASRQEDAADADLSSAHEGRITQTRDESEEEAKRKGLEAYRLRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4L1</accession>
    <name>A0AAV4T4L1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_68381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010615">
        <property type="protein sequence ID" value="GIY40462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4L1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9629" checksum="79A3D087A3F1F589" modified="2024-11-27" version="1">MILELDTTSKILRDMSQISDQYFYSRQAVKPFHPALPDTRPAQDPRTDSIHMCGILHRHKHAHNCRPRNSNWWHRARTLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T802</accession>
    <name>A0AAV4T802_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010897">
        <property type="protein sequence ID" value="GIY42803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T802"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12951" checksum="FB7CCEBD7A67F9EE" modified="2024-11-27" version="1">MHYFHSIPELMFFSQRQALKKKIWLNDMLHDIVENSSVSPTNKFLYGAFFSGVNEPLEFLYEQLSLGYLYFVIILLFTYSRERGVVSVPSTDKNNEFLLAFSFSSLDVFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIN3</accession>
    <name>A0AAV4TIN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_109903_1</name>
        <name evidence="2" type="ORF">CEXT_278251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011426">
        <property type="protein sequence ID" value="GIY46483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052997">
        <property type="entry name" value="RRT15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33047">
        <property type="entry name" value="PROTEIN TAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33047:SF8">
        <property type="entry name" value="REGULATOR OF RDNA TRANSCRIPTION PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15191" checksum="B7742B6A899DA8AA" modified="2024-11-27" version="1">MGSCPDAGLGRSGLGCPGQSRPVPVQCHTRFGPQPDGPNPQSNPLSRCYGSNLTTSLTYIVLSTRSCSPWRPAAGYGYGPARKSHHLRRFARADRSAPDTARAAVLLREQRPLSPDEPIPGTRTLTKKRRVFRRRLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJI3</accession>
    <name>A0AAV4TJI3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_251351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011215">
        <property type="protein sequence ID" value="GIY44952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14140" checksum="DDEAD73AB0555150" modified="2024-11-27" version="1">MLRLAKQIICQTIKDYFLHCNPAEPSAEEYVIRKGIFLSGFDFTHLEFCSDEVLYPPESHSSDAPISQPEFYLSLFLGTPRKARCNSRAFLTNWIPPPRVVPGTQISANCPVWTFFFFFTLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TK67</accession>
    <name>A0AAV4TK67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_550521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011431">
        <property type="protein sequence ID" value="GIY46510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TK67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="16641" checksum="B42A5F409B0728D5" modified="2024-11-27" version="1">MKGMVKVLTVYGGGCAGEHYPVGAEQPCYDAANDPEPPASTSARGHVGILPKSEPLTCTQSQKHIASHGQYGEEPLVFNCKYPVAAILKAVIRISSAFLRAGQFKVFRYERLINNSSDVLAVRAGWMVAGQRGMLQPNTDCSDAGKIWGRCNSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNC3</accession>
    <name>A0AAV4TNC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_562141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011422">
        <property type="protein sequence ID" value="GIY46472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8682" checksum="CB3E30FF316D7108" modified="2024-11-27" version="1">MFIRDGTAAGKHECLNVSAHPRDRLITSFLCISPGSRVGPFFPAGLPARRTLHRFVANLSRSSSASVLFFQNRMCCKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQD1</accession>
    <name>A0AAV4TQD1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Granulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_588751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011609">
        <property type="protein sequence ID" value="GIY47666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043719297" description="Granulin" evidence="2">
        <location>
            <begin position="17"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY47666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="20030" checksum="29624BF07459BDD6" modified="2024-11-27" version="1">MKVFLLITILPWLVAADVLCPDRITTCSGAKSCCEFDGFYTCCDTTTGEIDGHLLPVDSKLIDSNLTLTIQSAPGFDKQCPSGRYCPLNLACCGIYCCEMGGSCCDNRGCCGSFAPCCGTGCCRSLQSCCGGQGCCQVLSKCCGNWCCPSKSRCGTRRNTCYNSSVGLVPTIALISLLIGACFATKSNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TV29</accession>
    <name>A0AAV4TV29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LIM domain-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LDB2</name>
        <name evidence="5" type="ORF">CEXT_348493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the LDB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011940">
        <property type="protein sequence ID" value="GIY50110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TV29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030274">
        <property type="term" value="F:LIM domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000045">
        <property type="entry name" value="LIM domain-binding protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041363">
        <property type="entry name" value="LID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029005">
        <property type="entry name" value="LIM-bd/SEUSS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10378">
        <property type="entry name" value="LIM DOMAIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17916">
        <property type="entry name" value="LID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01803">
        <property type="entry name" value="LIM_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51957">
        <property type="entry name" value="LID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LIM interaction" evidence="4">
        <location>
            <begin position="318"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="355"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY50110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="421" mass="47225" checksum="135444BBC3A5CED8" modified="2024-11-27" version="1">MLNSGIGFPGPQNDPFYASPFSNYFRRHTPYFGQPDYRIYEMNKRLQQRSEDSDNLWWDSFATEFFEDDATLTLTFCLEDGPKRYTIGRTLIPRYFRSIFEGEVTDLYFSLKHAKESFHNTTITLDCDQCTMVAHHGKPMYNKVCTEGRLILEFTFDDLMRIKSWHFATRQHRELVPRSLIALQAQQQDPAMLEQLSKNITRQGLTNSTLNYLRLCVILEPMQELMSRHKAYALSPRDCLKTTLFQKWQRMIAPPGGSHRPGPNDFKMQPEVETQRPPSKRRKRKSSATNNANSTGTGSGKKKNMSPGPPNFSLASQDVMVVGEPSLMGGEFGDEDERLITRLENTQYDASAAAANGLDDGDDFSGNPVGPGPNPGGGPPPPSWSGAPPSQPPERNQTGGPGSVPQPQNQEDKKPSPAISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYM2</accession>
    <name>A0AAV4TYM2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase Tc1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_16422_1</name>
        <name evidence="2" type="ORF">CEXT_360901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011953">
        <property type="protein sequence ID" value="GIY50210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12592" checksum="E6040E2DD99B6ED0" modified="2024-11-27" version="1">MKAKTLREIGKIVGRTHSSIQRVTNNYTSSKSIISKPRSGRSSKLTAREKRYVFKSVRLNPRISAFQIANDVRERFKKTLHEDTIRKILKKGWVSWPCCSQEATHISCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3M8</accession>
    <name>A0AAV4U3M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_109256_1</name>
        <name evidence="3" type="ORF">CEXT_444511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012235">
        <property type="protein sequence ID" value="GIY52394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040676">
        <property type="entry name" value="DUF5641"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18701">
        <property type="entry name" value="DUF5641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5641" evidence="2">
        <location>
            <begin position="93"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY52394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="28636" checksum="C435CE0CB8EC3DB0" modified="2024-11-27" version="1">MKVFGLRKDEDKKTLRVKKQDLEISKVRTPTAVGLLTTATQELKKSCVFCGGLHTSVFQNTSPYTTLPSMFLQDVRDGSAPDIDDVEQRLLNKRFRYRQTLHKGLRNRFRSEYLGVPVQKPKRRISNTFKIGQVVLIGSDNRKRIDWPLGVITEFIPGKDKQVRLIKVKTSHFITPYSRINPLEIDSSKDFSSTFKDLEEQRRGDNVPNPSDLRDTSKRKISLDEMKDIGVPNITRTGRHVKIPEKLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8Y9</accession>
    <name>A0AAV4U8Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_221341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012489">
        <property type="protein sequence ID" value="GIY54263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13762" checksum="FBA00631329B9605" modified="2024-11-27" version="1">MNSLDVLADKNTALILKWALVKLENCSSSFESKILRYLKNSLSHRITTGRRFMKRHASQYHFPNKSCKGLFFLLTGPLTGRQNSARRFEISQMFAHNEDCRKRAAGAIQFHTQTHLSFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFK6</accession>
    <name>A0AAV4UFK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_533671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012783">
        <property type="protein sequence ID" value="GIY56587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10738" checksum="92CA0A5292B767BE" modified="2024-11-27" version="1">MKILDDIIATTKNSDLQRDYDQMNANLMQKRQLLAEWVSRVPCPLANCNIHHSNVKKSKRPVNELTNQNDKTNAAQEFKTPNKKRIAKSKLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFQ1</accession>
    <name>A0AAV4UFQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_24851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012781">
        <property type="protein sequence ID" value="GIY56581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10830" checksum="76A7C526812626AA" modified="2024-11-27" version="1">MRQLLIILQIKLKLREGMSTRGHTEGLAVGSQGKKIPPEYDELKNVTGLLRNCVFALLSSIQICTIRTHIYLHIFNIRIISLKVSIRLICFTLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHK6</accession>
    <name>A0AAV4UHK6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">AAEL008004</name>
        <name evidence="11" type="ORF">CEXT_517341</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="BPLR01012853">
        <property type="protein sequence ID" value="GIY57030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF69">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY57030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="25839" checksum="A34099B8C9385F7D" modified="2024-11-27" version="1">MSNFKEEVLLFFNNPGYYRSMLPFKEEVLLFFNSPDPRVAEWPLMDNPVTTIALVIGYLIFVKVIGPALMKNRKPFNLRLIMTVYNFSQVVVSSWIFINLGMLGWFTKYSWRCEPIDFSYNKDAVRIAEVCWVCFLLKFYEFLDTVFFVLRKKNSQITTLHVFHHALVPITVWIGIKYGAGGYNTLFPVLNSFVHAWMYLYYGLAALGPSVQKYLWWKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNF3</accession>
    <name>A0AAV4UNF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_444871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013202">
        <property type="protein sequence ID" value="GIY59411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="22681" checksum="F093C5A227979032" modified="2024-11-27" version="1">MSKSKSRGVMRVECVAKNEPEIVVAPCQGWSDPCEFCDKRFGNWLEANKETIAKIPTKPGIFTIGLKHKNSVELVDISIDKYDIQKLAYDRIDHAKERVADKKSKSTKSVVMCRWMTFKMSDDKDVTSLCAHWYNNGVLPKFLNSWPGSNILEKTDKFVFSNELQKWCYPKRCFLEETKNNTLKVAGSSKQLQLVSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPZ1</accession>
    <name>A0AAV4UPZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_580011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013245">
        <property type="protein sequence ID" value="GIY59823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14034" checksum="D5AD688A6D6E0931" modified="2024-11-27" version="1">MLSNLTNEERCARISRILMKKDIAQSLLDTFNATTFGHALDEDDHVKLKTLEQDLINALREVGNLELCPLIDCKKHKANVNNSSVNLKRNASHITTVNDDNADGFSKPSKKLTAKVNFTKVSPNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UR16</accession>
    <name>A0AAV4UR16_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="9">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DUS1L</name>
        <name evidence="15" type="ORF">CEXT_248871</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="9"/>
    <dbReference type="EMBL" id="BPLR01013292">
        <property type="protein sequence ID" value="GIY60183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UR16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="14">
        <location>
            <begin position="22"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY60183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="442" mass="50468" checksum="75C18B137BBC638A" modified="2024-11-27" version="1">MANKQTGYDFWRNVLHNPKYVAAPMVDMSELSFRMLCRHHGSQLCYSPMLHSLQFSQDFLYRKDNFSTCFEDRPLIVQFCANDPEVFINAAHMLSSECEAIDLNLGCPQAIAKKGYYGSFLQDDWDIIRSMVQKASYELPIPVTCKMRILPGHYKKSVEYAKMLEHSGCSVLTVHGRTREQKGHATGLASWEVIKEIKANTDIPVIANGNILTFDDVQNCLKYTGADAVMSAEALLHNPALFSGENLPVWKIVEEYLQLADKYNTPIKCVRCHLFKILYLCIYQDDELRKILTEGSTLKDFYSIIEILKKFPDKVNHATESVSFEQEPDLGNFFESANPDFQESAGRNVLELKTSCIANDNEHKFCDQTVKRNSALSDANENFISEMNARNENNSEATAPVLDDTFKYLPIWICHSRPRIAINEKSRGCFSKYFDSTSEKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UX84</accession>
    <name>A0AAV4UX84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_708071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013612">
        <property type="protein sequence ID" value="GIY62356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UX84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13255" checksum="35B0F8BB49726237" modified="2024-11-27" version="1">MSSYRTGLKESWTVSPDGKVTTRLALGRTIIGGNLVGNVSSEAPLHFHPHRGFEMDYLLFTKILKGPKVWAALRASPPRPAYLRAELCFACPPPASDELRAGSCPGRRMGPLAGTEHRWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VC57</accession>
    <name>A0AAV4VC57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_140641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014308">
        <property type="protein sequence ID" value="GIY67986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VC57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19781" checksum="E91CDF499690590C" modified="2024-11-27" version="1">MNLGVSFPSRNRKTVLPVFVILPDAERESKLRQNFARFLDCFIVGFLIYLISCDMYLASRDMKDAPFGFMIFASIGDFTSLFMRVILIRKRQCIGRMLRKTFALYRELDSSDKIRWHGKRLFAVFVISWILPSILYAKSVIFVMTEGRSQLSQIYLFFGNDVHENGVWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VI11</accession>
    <name>A0AAV4VI11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_243711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014584">
        <property type="protein sequence ID" value="GIY69776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VI11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10036" checksum="22E1FC91947926EB" modified="2024-11-27" version="1">MSLSDSGHCIRGPGGQSGRVEGDRRSLRSPVGLATAAKLAQTATHRHQHDPVGVSVRALPSFEEPDGPGNHGGGDPLHPPTSLCRPLRLDHPQPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W182</accession>
    <name>A0AAV4W182_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_205041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015444">
        <property type="protein sequence ID" value="GIY76163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W182"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13388" checksum="0A961817271C938C" modified="2024-11-27" version="1">MSRARKRNAKRGRSRMTPTARRRERGPQALLQGSRFLVRRVQDCSSPEACFVPSLLPTLLGTSHDSSWLVYCYYFFFPISQREREMLREPFKLYFASFILVSEQGRRIFSSFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W254</accession>
    <name>A0AAV4W254_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_5455_1</name>
        <name evidence="2" type="ORF">CEXT_635001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015474">
        <property type="protein sequence ID" value="GIY76333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W254"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="598" mass="67066" checksum="0B06E1E243419726" modified="2024-11-27" version="1">MRPIKPMVLKIPSTQSYTTDPPQYDNITESPEQNDTSKYVSENQQGYNYDKVQNEPYYTHDASADQTYQELPSESTDKQYSDTYYNEVDNPLMLQRLTSNIMWIIKILRMLTSRQRMLTKITIGVLSKIKTGLILDNRALNILQPQYADAYQDQPYGEYGDQSEYSTTQAYSQENYEYVSEGQQGAYGYPSESGHESYSNYSEPHSVEEQKSEIYYGDDKHERAAKSERFTSSPQHKGYSPQRSSKRRRQRQYSDPVTSSNAIPILSQTQVTSSGTITQATKELSSSATTVAEDTSTTAGGGILSVLSSKVSKGYKMMSMPTLTKKDTAPPTSATSTKSGSKSGSMTSIFNLGSTLDSFKIGSRTKSRSDSVKSDSELSVYDEPQADLVVDYPQEEVAPPPPIRDTYSLQQASVEEDHDVFTPRKSKKIIVCLRRNTMNREYNDETYYQEQDYQDNTGEYPADYYETQEVEEVEEDELPSSERTVTPFRRSGTRRGTLRTRPSPAPFPRSEPAQAPGGLGRVRDPDGKHVQRVCLFSCVSDSRQSSIAQSEYSSLGSMESVVPNDGAKQDGGSLESYGDRGQQDGSEEVSSQKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5P1</accession>
    <name>A0AAV4W5P1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_282251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015704">
        <property type="protein sequence ID" value="GIY77987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9578" checksum="A438BF96AA42E239" modified="2024-11-27" version="1" fragment="single">IQTLQELPTKLERDYESVRMNAEKGLHSKTRIGENLLSSNKITRLILSLLGTKKTMPPIGEPTITTPNNTILPQTTDRRKPQPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WC13</accession>
    <name>A0AAV4WC13_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 23</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mediator complex subunit 23</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED23</name>
        <name evidence="8" type="ORF">CEXT_97081</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015850">
        <property type="protein sequence ID" value="GIY79143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WC13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021629">
        <property type="entry name" value="Mediator_Med23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12691">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12691:SF10">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11573">
        <property type="entry name" value="Med23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY79143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="468" mass="54540" checksum="28C2CE47D19F1058" modified="2024-11-27" version="1">MPGATSFESNEAQVCFLIIRMLLLKSQEFKNRVYDFVKNNSPEHWKQSDWHEKHLMFHRIYQEKFYFEGLHDLNAQHTYLPVYFGNVCLRFLPVMDIVIHRFLELPTVSISVEGLLDTLGCLYKFHDRPLTYLYNTLHYYEQKLRDRPPLKKKLVTAIVGSLKDIRADGWALSEGYINYTQDTSEELNWIPDHDYYVQLIGRLVDTLGGKSPFPHTDWRFNEFPNHGAHALHVTCIELMSLPVSPAIVGNAVLDVILKQHTSSVHSNIIAWMNAVGVVLTALPEAFWNILNDRILEVLQSPLLANPPPQVNPFMMFNFADSYNSMTEFPCSYLVALTHAVWYHASIGQICTLTQLLKTKFKPAVKNEVQFIFICQLVAPYLQRFYMERTRYAMEITVELYEMLETIDKNCKEIEYIDPICDLLYHIKYMFIGDSIKNEIEKSIRNLRPSIQRKLKFITHLNIEEESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQV4</accession>
    <name>A0AAV4WQV4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable prefoldin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_672831</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016595">
        <property type="protein sequence ID" value="GIY84962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23161">
        <property type="entry name" value="Prefoldin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000003">
        <property type="entry name" value="Prefoldin subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00072592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY84962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14929" checksum="D76139B8D548DEAF" modified="2024-11-27" version="1">MGSEEFQKRLSQELDKIKNIQKNIQKAMAAKQTLDGQLSENTVVKEELEFLTPENKVYKMTGPVLIEQDIEEAKQNVEKRIMFISSEIKRNEELLKDLSSEQDKQQEILQRLQKEFTEEKQLKMGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WS86</accession>
    <name>A0AAV4WS86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_165101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016690">
        <property type="protein sequence ID" value="GIY85776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WS86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18269" checksum="F7558BD8A46BECE0" modified="2024-11-27" version="1">MKNNDFVIENYDVIKENYDVVVAALLSNTGYTDSPNKGKYYTIKPRVDTHSRIQKKVSCTSENIGQYRTPRYKESIVHPDTVSYTQRCREVLQYREALSVPPKYTGKCSRNTEEAFANTGKHLITQHRESIVKPGIHGSYSFHTSNTGKVIRSSSTKTISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWX4</accession>
    <name>A0AAV4WWX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_809791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016934">
        <property type="protein sequence ID" value="GIY87385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11525" checksum="3591C4A7D00C2635" modified="2024-11-27" version="1">MTGSFEWVFLTSQPCARRFHDDEKWRRAGHCVTEHSATYAPLRKSGRLSGCGVPFVRGTPRLPHHCSKRAFPLFCNLTIVWQEKKNNYKKENYDRLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1G8</accession>
    <name>A0AAV4X1G8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartate--tRNA ligase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Dars2</name>
        <name evidence="7" type="ORF">CEXT_746291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017132">
        <property type="protein sequence ID" value="GIY88962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1G8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class II (D/K/N)" evidence="6">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY88962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17841" checksum="2BC341C6E1B153B1" modified="2024-11-27" version="1">MDNFSFVWITDFPLFLPKEDGTLESAHHPFTAAHNEDIDLIYSNPLKVRSLHYDLVLNGQEIGGGSIRIHDANLQKYILEDENSSDLQHLIDALNSGCPPHGGIALGIDRMLAIMCGCRSITEVIAFPKSLDGKDLMSGAPCSISNEDKQLYHIEPILPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3R3</accession>
    <name>A0AAV4X3R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_364221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017269">
        <property type="protein sequence ID" value="GIY89901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10883" checksum="A3725A516D7113EE" modified="2024-11-27" version="1">MLPTAGPIQWSLPDSRYIPETGLDFNFGRKVLTDRETHFVMIIRTGTVRFSPSIPFPYLPLCPPLIANHTHRTAAGFGMESKGGVVIKTEFHSRSGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X604</accession>
    <name>A0AAV4X604_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017227">
        <property type="protein sequence ID" value="GIY89600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X604"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12881" checksum="CF32920E713B6DFF" modified="2024-11-27" version="1">MRAVDLVLVEFLVRAEYVSKTYSSIKSINCHQQEYTKIIEDIFHKVSLSAAFKVLEYSPFKSDREMSLISTQRSRKLSYTNALAGVLNNLWSPILSGYSSQPVVRTTGQDITGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7H7</accession>
    <name>A0AAV4X7H7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_119141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017382">
        <property type="protein sequence ID" value="GIY91102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7H7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="25476" checksum="3A85F4C60EA46C96" modified="2024-11-27" version="1">MYQHLKERLKYIDSAKELLQGPLVEEPPPPEVEPPPPEEEKVESVNGRVPCIFGIFSTLRPVLKEGHLVALAPGGVMEAQFGDEEYSLIWGKRIGFAKVAIEAQVTAELILQCPDLHQKKTIWYDEDSLDFLTASSSGLCILHAEIFWVAYGIWKGLKVFEFVNKELVSLLDVSLQVYKQYSRESNKCTVIAFPPWKCGILRSYNSFARSISPTRRYTFSCGDGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9B6</accession>
    <name>A0AAV4X9B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_804301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017442">
        <property type="protein sequence ID" value="GIY91675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15248" checksum="A574407A7CB2ECA7" modified="2024-11-27" version="1">MRLVTAEYSEIVDTNPLSNCPFQADFVARYLFFMTVTAKNPVLPKDDFKNKIIICRASSVRKDIYLFTFTSEILSIPCCKSSLSHSCGRITRLFSSAEINPGGRILNPCKLIDIFTLKVFLKLVGRDKYPWTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBN7</accession>
    <name>A0AAV4XBN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_291501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017559">
        <property type="protein sequence ID" value="GIY92587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11685" checksum="4A9ABB9B71DB5D58" modified="2024-11-27" version="1">MPVIRTNHSKWYLSKEKYGEDLYPHYCSGIGLHLHLRCSGSHLGTVKSTLPLESAEDCSRDRDARVRWDWPRKDRQSVCICITDEEKNSQWSNDFCSPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEZ3</accession>
    <name>A0AAV4XEZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_553041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017709">
        <property type="protein sequence ID" value="GIY93801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11819" checksum="9B0F089FF2D4D165" modified="2024-11-27" version="1" fragment="single">MELLINDVLHKLACMHCFIKEFYAKTCVEYRKTIRMVCQAVWMKPMIYDELQLNFFMDFYHQMRDSPEKYLTYVIYACNLIAENEPNIFQRFIDIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLY0</accession>
    <name>A0AAV4XLY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_206891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000514">
        <property type="protein sequence ID" value="GIY95393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9900" checksum="59560622940BF906" modified="2024-11-27" version="1">MDLDREQNVKRVLLQELFMLAVWQQHHQQQQQQEKESTRVLFTSGARFECLNTPRSQNGIVTYARNHKKPQVNRLDFSMNKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPZ9</accession>
    <name>A0AAV4XPZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Dscam2</name>
        <name evidence="5" type="ORF">CEXT_304641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018045">
        <property type="protein sequence ID" value="GIY96413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000104">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="11"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="111"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY96413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="254" mass="28375" checksum="C02526211266A1DA" modified="2024-11-27" version="1">MTTHLIVNVSPQFTVEPTNSTVVEGHTVRLDCAAVGFPAPSILWKKLIYSRNTAGDFAYVHSSPRAHRYSNGTLVISDAEERDAGAYMCQANNGIGAVLSKIVSLQVLASPRFKESFQSQSTREGSNATLKCDATGHAPITITWQKNKNILDSKSNERNSAQYFPAISSPEEMLYSSHIYPGQSGLDAEKFHSIYHIGHRTIFPTVTQLCNYKSFQVLKKYYTSLHICHTVWQSRCEQLQIGLFVEHRIGLSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XW60</accession>
    <name>A0AAV4XW60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_493361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018270">
        <property type="protein sequence ID" value="GIY98221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XW60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11842" checksum="F091EBD4A0244735" modified="2024-11-27" version="1">MEEENIMFLNSKLCRQLGAVYNRDRTVYGLRRYLQIFHQSNACFCPIGGTKRSGRIDPFVLNLGARDRCRRPLFVLQGAMDRGEIGIDLGFKSILKILSLLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX38</accession>
    <name>A0AAV4XX38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">COP9 signalosome complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Gps1</name>
        <name evidence="9" type="ORF">CEXT_281261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018349">
        <property type="protein sequence ID" value="GIY98858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048624">
        <property type="entry name" value="CSN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21151">
        <property type="entry name" value="CSN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="COP9 signalosome complex subunit 1 C-terminal helix" evidence="8">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY98858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11565" checksum="12E04B8FBFE7740E" modified="2024-11-27" version="1">MAAAFNTTVNGLEDELTLLILDNQIQARIDSHNKILYAKDIDQRTTTYEKAIKMGKEYQRRTIQLILRSAMLRSQIQVKSPLREGSQGIDVSVAPLNHSPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXS6</accession>
    <name>A0AAV4XXS6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_166751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018434">
        <property type="protein sequence ID" value="GIY99564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8565" checksum="62B951DD52BAE02E" modified="2024-11-27" version="1">MAIDCNPFLPPFCRALWWTMLLGVDLLIYSEISARLPAMTRKVSLFLFFVPMGQLKTTFWEVPRSLDVRAENEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY92</accession>
    <name>A0AAV4XY92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat neuronal protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LRRN2_0</name>
        <name evidence="5" type="ORF">CEXT_779541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001078">
        <property type="protein sequence ID" value="GIY99714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="LRRCT" evidence="4">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY99714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="229" mass="25130" checksum="DB1E484357AE77B7" modified="2024-11-27" version="1">MHANGLSALSADIVRPYREKPLQISLHQNPLVCDCNVRWIAELLAGGNESVRIQEGALLCRGPRGLEGAHVASLDLSQIAESCAPVLAVGSTNHTVEKKVGDDHVFECRAHGLPPPVLHWVLPDGQVLNQSSDDTRLHLRGDREACPCTPSASRMRGTTRAWPSTLWGRRWACRGCACRAWTSTCSLRGVGHLRDARVERDGAQRLPRVRDRVPARGWWGRGGTDSTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZZ5</accession>
    <name>A0AAV4XZZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_406301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018407">
        <property type="protein sequence ID" value="GIY99300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8548" checksum="9CACC34239DC4F85" modified="2024-11-27" version="1">MGLDIFLKLFFSSLYIKKYKRFTMKRKQPDFQKVKFKVGKHLPKGRNETKTSFQTRKILVPTQLKAVNVEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZZ6</accession>
    <name>A0AAV4XZZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_570711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001123">
        <property type="protein sequence ID" value="GIZ00124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="13794" checksum="4548E60B90A2105B" modified="2024-11-27" version="1">MGIEDLKRPEHGSRNMQSMRSHRSPKAKLSKVGVVPNTLKMLCKMSSYQTRGSGLKPALMPSEAMMPDRYYNNKRFPSTVSLPGGLLCLPSPSCQNSYPVLTFHVLKSHGQLGHVSVKTGIPQNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0H3</accession>
    <name>A0AAV4Y0H3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_363731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001161">
        <property type="protein sequence ID" value="GIZ00510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0H3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10845" checksum="C90AB0ACB1176810" modified="2024-11-27" version="1">MRPLPTPSATYHGRERSSAQHSRCATWHLLLEMRLSSDGFCQSAGDHQVSLTNCSFHPPLPPNAACRSTGVKGNKIWCRGNPALTTKPHQYCVAMNNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4Z1</accession>
    <name>A0AAV4Y4Z1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_692971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018685">
        <property type="protein sequence ID" value="GIZ01550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4Z1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12339" checksum="0969C9CBE39863F7" modified="2024-11-27" version="1">MHSKPLRKEDFLLVRLSTERIGGDKILEFGFLCLKNLRRNHPVECFNCWKVTPLLTRWLVDIFRFHLHTEANTIYCGEDKMVNCFYQERMVFIRFYSLAQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7F1</accession>
    <name>A0AAV4Y7F1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Invertebrate defensins family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_77491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001390">
        <property type="protein sequence ID" value="GIZ02064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7F1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.10">
        <property type="entry name" value="Knottin, scorpion toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001542">
        <property type="entry name" value="Defensin_invertebrate/fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036574">
        <property type="entry name" value="Scorpion_toxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01097">
        <property type="entry name" value="Defensin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57095">
        <property type="entry name" value="Scorpion toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0044">Antibiotic</keyword>
    <keyword evidence="3" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Invertebrate defensins family profile" evidence="6">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ02064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8186" checksum="A6DEE67D8D6ACBC2" modified="2024-11-27" version="1">MKNNNALLSPTVRTSDNVFDPGASAVNVCPSDWKACDSKCKTDGRIGGYCGGLWSARCTCVRRKVSITSDVIPFIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8P3</accession>
    <name>A0AAV4Y8P3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_40391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001598">
        <property type="protein sequence ID" value="GIZ03390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8P3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7453" checksum="676399802DD3DED0" modified="2024-11-27" version="1">MNADEKKILLENTNGVTSPFQGTVGKKKKKKKGNANRHGIGMPGANEVNVTSAKTSAAAGISPAMHGKPTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9A7</accession>
    <name>A0AAV4Y9A7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 4-kinase beta</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PI4KB</name>
        <name evidence="11" type="ORF">CEXT_356731</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19878"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Rough endoplasmic reticulum membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01001471">
        <property type="protein sequence ID" value="GIZ02526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9A7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030867">
        <property type="term" value="C:rough endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000004">
        <property type="entry name" value="Phosphatidylinositol 4-kinase, catalytic, beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049160">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21245">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="10">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="458"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIZ02526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="740" mass="82750" checksum="22FC1A1FD3A4D4D2" modified="2024-11-27" version="1">MSINVRATRGCFTRVCACLPVIRSRATRNSPSSPPVTELVTVSESGTKNRSVRGSHTENRATASFLSGNRMFTFEDQSVNFYLPQLVSLYVHHSDLAEAIHPYLVYRCRNSVEFSLQLAWLLQAFCAENTPSRKKSQGSKLKKMILSEELRPKESSKPCPPVGPILSPKKTHQRSYSDATGLGGNTVMRRSVSTAGNLNKHAPKDLASGHAFDNGCKCFDSCKSICSDLRGQVVHCSCQAPRLGAQQDFVQALMSIGLRLQPVLTKELKSDSKLQAELSMLNLNLPARVWLPIHSETMKHLILRIPPQASVVLNSKDKAPYLIYVEVIEVDDIHGSPVPPKMINALRQTRSEENLPDFFCNQDFSGVSFSVHPAMDDDADCWTQEDDAISLQYAACLKPKDRDALSEMSQDSGTSADSREPAYVAAGEIRRRLSENINAPKSTFKRDPEDPSAAALKEPWEEKVRRIRESSPYGHLPSWNLLSAIIKCGDDLRQELMAYQLLATLQNIWESERVPLWVRPYRILVTSEDSGMIEPILNTVSLHQVKKHSKMSLLQYFLQEFGGANTEAFLSAQRNFVQSCAAYCLVSYLVQVKDRHNGNILLDGEGHIIHIDFGFILSSSPKNLGFENSPFKLTQEFVDVMGGPGNDMFEYFKILMLQGLVAARKHHEKIVTLVEIMQASCQLPCFKNGASAIRALKDRFHMGLTEEQLQLLVDSMVESSMHSITTKLYDNFQYITNGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD71</accession>
    <name>A0AAV4YD71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Out at first protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">oaf_1</name>
        <name evidence="2" type="ORF">CEXT_449471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001735">
        <property type="protein sequence ID" value="GIZ04439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026315">
        <property type="entry name" value="Oaf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053894">
        <property type="entry name" value="OAF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13423">
        <property type="entry name" value="OUT AT FIRST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13423:SF2">
        <property type="entry name" value="OUT AT FIRST PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14941">
        <property type="entry name" value="OAF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Out at first protein BRICHOS-like" evidence="1">
        <location>
            <begin position="29"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9779" checksum="795C9A8BA74256CC" modified="2024-11-27" version="1">MFHIAYTEIIIFIFVVIYNLDNLKNCECQLVINVKNQGGDIVQESIISNITDDTITLEFQRPEGTLITQFVDFKSEVQIFGACFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDW4</accession>
    <name>A0AAV4YDW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA mismatch repair protein Mlh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MLH1</name>
        <name evidence="2" type="ORF">CEXT_87861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019071">
        <property type="protein sequence ID" value="GIZ04357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000079">
        <property type="entry name" value="DNA mismatch repair protein MLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="250" mass="27609" checksum="2070B1318C1E6AB8" modified="2024-11-27" version="1">MVGIIKKLDETVVNRIAAGEVVQRPASALKEMIENSLDAKATSIQIIVKSGGIKMLQIQDNGTGIKKEDLDIVCERFTTSKLEKFDDLSSISTYGFRGEALASISHVAHVTITTKTEDSKCAYKIQYSDGKPLQPPKPCAGNKGTQILVEDLFYNMSVRKNALRNASEEYAKIAEYGEGSSDVHTLANSTIRENIRSIFGANIAKELLDIEIEDEKLRFKAKGLISNANYSVKNALSYYLLIIDWLKAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3F0</accession>
    <name>A0AAV4M3F0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_80951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001826">
        <property type="protein sequence ID" value="GIX66879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3F0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14839" checksum="D2B1472917FDB6C0" modified="2024-11-27" version="1">MSFRALGRGMVDWPNWRGVAGCDVIMIDGLCWMECHTDLTLNLPPFSTSLSFSDTPLSPPLLLDLLLIPQKHGLALVEKIHPPIRGMHAEIHSPIQVIYSKIHSPIQRMHAEIHSPFQGMHSKISSPIQGISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M705</accession>
    <name>A0AAV4M705_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_142171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019420">
        <property type="protein sequence ID" value="GIX67668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M705"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10518" checksum="013E4EB422C03574" modified="2024-11-27" version="1">MAICGLDWRIRVSPMGEKKDVGNDNKKKEAEKCAVRWIFCGAYPIDIISEDSDQEEDAGEVILEQSDAPVGSENGVLDDKDKGKAESKEDTEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDS2</accession>
    <name>A0AAV4MDS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002122">
        <property type="protein sequence ID" value="GIX70221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21589" checksum="A009541EE8767BBD" modified="2024-11-27" version="1">MLPELRRLRRASGTIISDVLVDIFGDCWLVGCSWSYAGEILPLSNCAKSFDDNLLPIDFNALTTKCDIISREIQDWRSICSDVTEHANGLMSAEINSLTFPRCRMKQVDIINFLDVVTSHQKVLEEIFDRNSDLRLTLMQHDYDALLKKILEEELHLLDMMRNLSEAHFSLLQYDNKLKLHEMSLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MF95</accession>
    <name>A0AAV4MF95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serpin B6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SERPINB6</name>
        <name evidence="6" type="ORF">CEXT_188261</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002058">
        <property type="protein sequence ID" value="GIX69494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MF95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Serpin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX69494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="22448" checksum="6B2CB301839C8FB2" modified="2024-11-27" version="1">MIPNLLESLNPATVMVILNAVYFKGFWMHQFDKEKTFLQHFYNKGRGNFHANFVTQCKEWIRKIGNFPNPKFCSRPNTGNDQKKSEVALPKFKLEYSKSLKKTFISLGLKRIFGAAQLDGLSDYRDVQVSKIIHKAVIEVNEEGSEASAATAIIMVRCLKPKPIIEKFIVDHPFMFVIYNSRNNLILFMGRVNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MI53</accession>
    <name>A0AAV4MI53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_45641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019768">
        <property type="protein sequence ID" value="GIX71583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MI53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10862" checksum="1D8A21299592B94B" modified="2024-11-27" version="1">MEKENCYSEQIVDIDDPEVQTDPETNKRKMRLGTHRYRNFKNSPRSVRVPATIDWRRRFVQVVSNVVRRFRNKRRGLKFFFFPCRKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLC6</accession>
    <name>A0AAV4MLC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_601841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002403">
        <property type="protein sequence ID" value="GIX73374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9720" checksum="4324B389C72A0E33" modified="2024-11-27" version="1">MLWVLPQQRKLFSKKFTVGSVPETTPQKNAISNRMQKGSASTAREAMQPFTEDARISQSGILHSKNGHNQPLRKSQEPRSTSKKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQA9</accession>
    <name>A0AAV4MQA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARSI</name>
        <name evidence="7" type="ORF">CEXT_409831</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020013">
        <property type="protein sequence ID" value="GIX73983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047115">
        <property type="entry name" value="ARSB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342:SF273">
        <property type="entry name" value="RE14504P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX73983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="18651" checksum="E52D69D767DB1179" modified="2024-11-27" version="1">MLKNSIVLFVSDNGGSLNPDAGAHASNYPLRGKKSTQWEGGIRVPAAIWSPLLKLDKPRISNQLMHVCDWLPTFYSIGGGDIADLGQIDGYDQWEALINDSSSPRKHMLQNLDSVLGMSAFRLGDLKMVNGTASDEYNSWYGPSGFESVVCPLHSNGFLKMGARRERHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWU1</accession>
    <name>A0AAV4MWU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_545991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020247">
        <property type="protein sequence ID" value="GIX76354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="20982" checksum="810CCDCDE6055EA7" modified="2024-11-27" version="1">MNDPTRPSLKLPTLQDLVSENSNNTLPTSLCSSPHNLLSPDIGPPNLEICVLLALLRDTRPSFIQFYFDLHHSLFFNLLDITNSILNNNRIYKQAPLKNIQIIVINTGEPTVDHLLVYPTTEQNNIIDNCLKPTVTFHTINHTPTQTIPDITIELRQRTVDELITYPTIEQFLHNHNVLKPITM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3U9</accession>
    <name>A0AAV4N3U9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_330631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002945">
        <property type="protein sequence ID" value="GIX79495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3U9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11602" checksum="AF14ECD354C1904E" modified="2024-11-27" version="1">MHRTRKTPIDYLSAEIYVAKEDVFPLCQCCTDVAPLEDQFSFAENWKGRDGAGGGKRPVVSRLNHRQGPTINGHRGIIGGPERFAFGNRLMLMGCPPTSCQWTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N509</accession>
    <name>A0AAV4N509_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_77551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020537">
        <property type="protein sequence ID" value="GIX79802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N509"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13063" checksum="EF65C88FC62B389C" modified="2024-11-27" version="1">MSSNNARGQPALIEVNVYQNVRLEFGIDLNAFVSKHHKFDASTHTTIQLNATGRSFVATKIVLRLENPEIPRRRRLNLDSPLCPRWRFLSSVAETAETIRNSNTNLETAFRNPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6L6</accession>
    <name>A0AAV4N6L6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_419841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020482">
        <property type="protein sequence ID" value="GIX79331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043808700" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11989" checksum="7244B5BF2A97EF40" modified="2024-11-27" version="1">MHSLTRTCSSTAFFSLFFSSARASIPWNSTHNPGQMHNDLGRSEYSFGMLFFPRTCRQEGSFQYVQGELPEFNHGQSTVSFTNSCSVPRHQWPLHARHQEGFLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9V7</accession>
    <name>A0AAV4N9V7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histone-lysine N-methyltransferase PRDM9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PRDM9_0</name>
        <name evidence="1" type="ORF">CEXT_672521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003014">
        <property type="protein sequence ID" value="GIX80277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9V7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="22127" checksum="01A377CABC928020" modified="2024-11-27" version="1">MNESSNLNKNVKNSFSSDAWTTLSEYEKRRFENVQKNFEILKASGITPKMPEFLMNKFKRPQIKRLKTDADSTQPKGTDDCTPISLRTASPKEFAQELLGSAQNILKLLEAKMQGVSKNPTCPIKDLLLPHSNFLPGESQKGRYPKRNIQRKCYKEEDVPDQDEYLHCDVCNEEYEGVCPVHGPMLLVCDTKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBU8</accession>
    <name>A0AAV4NBU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_660021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003166">
        <property type="protein sequence ID" value="GIX81795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13728" checksum="5BF37B8ADFCAC67D" modified="2024-11-27" version="1">MAEGMDQSNGHPQFQPENIYSKTLLIPHEDVCSRIVSCPHKKIVRTTVSKNIKAFTLCNIHGRREILRPLVLAKQSSGTHLRHRKTCLVLISGRSSVLCRMSSTTYGVRILLPRPVSYMSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMB2</accession>
    <name>A0AAV4NMB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein glass</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gl_6</name>
        <name evidence="2" type="ORF">CEXT_107111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021015">
        <property type="protein sequence ID" value="GIX84948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043405509" evidence="1">
        <location>
            <begin position="18"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10056" checksum="77C063DCBCB465C1" modified="2024-11-27" version="1">MLTKLSLLLLLKRKTVTKDYIPRGVQYNSPSPTHPTAGASGTYTFTAEFRPADSMSLPSIEREYSNCGSNLKSMTGSFYPYKAWICNCSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ02</accession>
    <name>A0AAV4NQ02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_442991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003585">
        <property type="protein sequence ID" value="GIX86385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9686" checksum="EA45D0D0DBA10831" modified="2024-11-27" version="1">MPAELFHRNCNSFRSCVEVTTRINSDAELGFIAETNDPCRSLMGGHFRLLYPSPETNSNRFVQNAFFSKVNKTALIGNFELASQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWN8</accession>
    <name>A0AAV4NWN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_563771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021399">
        <property type="protein sequence ID" value="GIX89176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11475" checksum="FDC5F6B5C0E81158" modified="2024-11-27" version="1">MWIVIFDSGAKFSSRTLWYSFIHVKPTSTSNHNTQGETGSMWTIHPANQKGGRSKPRRNSSGRKFFNESPGEKIDTVGADDSFQRKREVEVIPCFHKTWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0N5</accession>
    <name>A0AAV4P0N5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_406071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021476">
        <property type="protein sequence ID" value="GIX90128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12070" checksum="A8B96A5581C6C472" modified="2024-11-27" version="1">MRFLHFFESCIWIDSIFIRGVGFKNKLRNIQPYRPRSTLKILGGGTLSVWKSDRVGFFAKKQKQGRRGLSSAENGLILQKCRGDPIKRSITFGLVILAGNWTFPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4R5</accession>
    <name>A0AAV4P4R5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_270609_1</name>
        <name evidence="2" type="ORF">CEXT_387091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004114">
        <property type="protein sequence ID" value="GIX92297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4R5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="1">
        <location>
            <begin position="217"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="412" mass="46892" checksum="B3039ADB769A85F8" modified="2024-11-27" version="1">MDSVEVHIFSDASIEAYGAVAYFRYVNLRGEVGTSFVMSKSRISPLKKLSLPRLELMGAIIAARLWKYLSKVFLWFGRRGLENPADKLTRGENSHTLLNDSVWWQGPVWLRGSRNQWPRQKFERVTDEQKLEKLNTSVHAILPLTEMILDENKFSNLRKLLRVTAWLLKKNKPVPPHSKIYSLVPYVDDRGILRVKGRLEQAELLHNEKHPAILPKSKFADLIIMSEHVKSFHSGVVSTLSRVRNNFWIPRGRQVVKKVISEYLICKKRALKPAKPLTGQLPRDRVVESPTFAVVGIDFTGAITIKAGDQSYKKVYIALFTCAVTRAVHIEVVSDMSLKSFIFALRRLLSRRGGCKVIYSDNAKSFRCVCEIINGFKKINVDQVFKSLYRPRALRGSSSLNVRHGGKAFGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P686</accession>
    <name>A0AAV4P686_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_235933_1</name>
        <name evidence="1" type="ORF">CEXT_591661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004136">
        <property type="protein sequence ID" value="GIX92544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P686"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10326" checksum="694C7F84FCF5AF58" modified="2024-11-27" version="1">MMELKEFRNAYYIGLVKFGDVQELMARMHRIMPLITRSDDSYDPHSGTKRFLPGEIRVRDHNHWGSGRINGLAHQACNLNYRATYFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P871</accession>
    <name>A0AAV4P871_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polypeptide N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Protein-UDP acetylgalactosaminyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GALNT14</name>
        <name evidence="12" type="ORF">CEXT_683361</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="BPLR01021684">
        <property type="protein sequence ID" value="GIX92361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P871"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23441">
        <property type="entry name" value="beta-trefoil_Ricin_GALNT14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02510">
        <property type="entry name" value="pp-GalNAc-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045885">
        <property type="entry name" value="GalNAc-T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF128">
        <property type="entry name" value="POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4 10" id="KW-0430">Lectin</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="11">
        <location>
            <begin position="466"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX92361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="615" mass="70535" checksum="6261FB2C111EB3DD" modified="2024-11-27" version="1">MLSQLFGSSFELKAKMTQKYIVLVSGIQNSTNETKQKGLVSFKGKQCVCGRDRCGLISTCGSALMWRVRKRRFLCLGILSLFLVYVVRVEISKSYENRKQKFQDSLTSDLSVKPIVLEFDHERYISGENRTGIHNFNKHSFNLQVSDATPVDRSIPESKDAKCKDRVYNIPASYSISVVISFHNEARSALLRTIVSIFNRTPERLLKEIILIDDFSDNVQDGLELANFPKVKVFRNNQRQGLTRSRMIGAVKSTGSHVIFLDSHCEVNTASKALVSPVIDIIDAETFQYKLSTGNLKGGFDWALNYRWQKVSEEENKDSDDSTFFKSPVIHGGLFLANKSWFNELGGLDKGLDIWGLENIEISIKTWLCGGEVLTVPCSRIGHVFRSHHPYSFPPNGSLSTYHRNSRRVAEAWLDEYKYQFYQVKPQAKRHAINSIEGIQSLKRKLKCKPFQWYLDNVYPELKPTSKDVVAMGQLQQENLCLQSQIVKENKTIISLVPCAANKSEQEWHFTKSGELQQGKNCLTAKLNVKKPKIYLGKCTNNTKQKWTRRRRLLILQGLCLENTMDTVIGQFYLTLNPCRQNAFSQRWDFSVELQSWDDRYFKLGKMVGFQQMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PC98</accession>
    <name>A0AAV4PC98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_662781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004296">
        <property type="protein sequence ID" value="GIX93786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PC98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="21345" checksum="CFCE0EC66CBA07F9" modified="2024-11-27" version="1">MRICSNTNKTEVLSRTIITQQYSELVKTEASTEEGAKGQESIFPNESAFYITANELCSYVPSDNKADNTADHKFDTILMRIWANANTTEVLSLTIIIQQYSELAQELKTVKTEASRDEGVKSRSNGAKGQESILPSESAHIDANELCSYVPSCYKAENTADPKCDMILMRIWSNTNTTDVLSRTIVTNSIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDD0</accession>
    <name>A0AAV4PDD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">39S ribosomal protein L12, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MRPL12</name>
        <name evidence="5" type="ORF">CEXT_24941</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004376">
        <property type="protein sequence ID" value="GIX94448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX94448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10287" checksum="FE25F0BEE9427096" modified="2024-11-27" version="1">MMMGVAPVAAQAAVEEDNEPEVTKSSFTVKLTEFDASKKIALIKEIKNFMEGMNLVQAKKFVESAPQIVRADIAQDEAENIKKALEAAGAKCEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PE80</accession>
    <name>A0AAV4PE80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_256151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004542">
        <property type="protein sequence ID" value="GIX95617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PE80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16420" checksum="3881B6B351E7382F" modified="2024-11-27" version="1" fragment="single">EIPDFRAIRSSLKILAMDNSRLTQLRGDNLKNLTRLWALSFVNNSITYVAGRRLSGEDTITTLYLLFNSGTENVTHFDISHNLLTYLPPVCSGPGNAWRLCGSPTTSCCTWTTSFLERTPRNYRKHPSYPRHRLDTKRIKECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PH76</accession>
    <name>A0AAV4PH76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized HTH-type transcriptional regulator YjiR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yjiR</name>
        <name evidence="2" type="ORF">CEXT_280842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004516">
        <property type="protein sequence ID" value="GIX95433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PH76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858:SF1">
        <property type="entry name" value="LD15494P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="106"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="485" mass="54970" checksum="3341F6CAA230101B" modified="2024-11-27" version="1">MRLNTTVAYLKAVGRIGHPEYYALDIFHENVDTYLLQLAWHFLASEFLQNYMEHFLQDLKHNIYENTSILMADEKHIVPQEKRFFSQFERQGYYNNDASSYANALKSDAQIFQYGVENGNWQFRSFLATFLTQEYGDVVSSEQLFLTGGASSGLWLVLSALIKAGSIVFVEDPSYFCALKVFSDLDLKVVPVKTDDNGIETDDFEKKLIQEFSENPSATYPPVKAFVYLIPVYHNPTGSILPAERCNKVISLARKYGLTIICDDVYNLLHYDDSPVCPKRLFAYDNRSHQDYVGNVISNGSFSKFLGPGLRIGWLEAPKWTIKILEDFGIIGSGGGLNTYTAGVITSLMALGKMKSHLQKVKTVFKTNMEATVDLLKQELPSGCKLKSPSKGGYFLWIELPESVNGLHFLPFAKQEYQVTFMPGIRGSPTNSFANYIRICISFYPLDVLLSAVRRLCQAISDFQHKCEDDPNFYETYVNSIKLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJ22</accession>
    <name>A0AAV4PJ22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_361071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004673">
        <property type="protein sequence ID" value="GIX96634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJ22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9351" checksum="DE058196FBEBB3C2" modified="2024-11-27" version="1">MINYCKGSLEDMQKLGWVTSLTLLLTTALTFTPSQNLYLLLGCSAPDQRVLQHAVLLGIAEEKRVTLVRSPRWVRRFEQAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJX2</accession>
    <name>A0AAV4PJX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_102891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004770">
        <property type="protein sequence ID" value="GIX97366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX97366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="21387" checksum="990B496AB6831B74" modified="2024-11-27" version="1">MVKEQTVVATDLWVISLVDSSPILLIRFGLVARLGTRFKPHNFKYYLVVEVPFKRKKNPDEANSLLGSRRYGKNCPTGRLVPNRKLVLRGTWLFVCVSSLLHKKRRERCPMRLPPLLKGTGRKRRKQASGQQAGTKHEKKREEGFFSLLVFQQKAPDPFSRPLVIPLSHSYVSPPFAHWRLRCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKJ8</accession>
    <name>A0AAV4PKJ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_332921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004750">
        <property type="protein sequence ID" value="GIX97189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9972" checksum="74AE0B78F3FF2E12" modified="2024-11-27" version="1">MSGQSVGLLLLSAEMVTRERSKDSICLAASWTAHHSSWCFFPRPESSERGCRYRFLSPQAGKSHRQKYEVIRFVDIRVEEFQVYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PL67</accession>
    <name>A0AAV4PL67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_577271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004814">
        <property type="protein sequence ID" value="GIX97738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PL67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7988" checksum="0FC03DE913A3BEA0" modified="2024-11-27" version="1">MLPLREQCFHAVLHSSERSFWKEWVERAEGGQRPLNPLTRSPGDVNGGLFFLYHLTNWAACSIESSKNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPW7</accession>
    <name>A0AAV4PPW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U4 U6 small nuclear ribonucleo</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BpHYR1_054030</name>
        <name evidence="4" type="ORF">CEXT_720821</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005048">
        <property type="protein sequence ID" value="GIX99457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000411">
        <property type="entry name" value="U4/U6 small nuclear ribonucleoprotein Prp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="19"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="146"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="188"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="231"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX99457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="266" mass="30136" checksum="9219080BF24CC7B2" modified="2024-11-27" version="1">MEGLCKLWSVPDCELIRTLRGHNCNVGAIVFHPQATLTQSETSVNMASCSTDGVVKLWDLKKRGMLHIEYHELHFIHLADFWLHVFDNSWRLWDLEVQEEILHQEGHSKSVYDASFQCDGSLLATGGMDSFGRVWDLRTGRCIMFLAGHQNSVLSVCFSPNGHQLATGSADNTVRIWDLRRQKCEYTISVHTDLVSRVLFEKTQGEYLVTASYDNSLKIWSHPGWTPIQTLCGHSGKIMGADISADDRYVATASFDRTFKLWAPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRR9</accession>
    <name>A0AAV4PRR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004992">
        <property type="protein sequence ID" value="GIX98993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11549" checksum="E75FD34666BE59BB" modified="2024-11-27" version="1">MQEAAIHFKSVTMLCSSYSDAISACTCSQRIILGLQKWPTNIRISSASIFKKILSHCAMPIPMFAERGQSALTCGIVLKWVRDSVYVTGNDIHSELVVVLIAMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSJ4</accession>
    <name>A0AAV4PSJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_33541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005007">
        <property type="protein sequence ID" value="GIX99111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="17501" checksum="3594102CE81A13E0" modified="2024-11-27" version="1">MVTFNVEWNVSYNDWGRNALHQSFFYFAYQRASNYSQNSGTNAAAIPRWYSESQTLHDRPPDTGMEKKQKQEQNNKRKPAYRGVWQKRKKGCPGICHFLPPFSSYPHLSLSLLKTSLLAYNETRKNCDLWTYVNPVEICNIERRKMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PT09</accession>
    <name>A0AAV4PT09_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase aspartic putative domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_175291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004892">
        <property type="protein sequence ID" value="GIX98337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PT09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10848" checksum="C81D705686F8F692" modified="2024-11-27" version="1">MPSVQTISPYNFMSRNSGKKCESVAGTKGSTTVQATMSIPSCMREVLLMTLMVEVVSGNMGKRVRCLLDCGSQRSYILRSTAEALHLKSLSSEKLTVAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PU84</accession>
    <name>A0AAV4PU84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aminoacyl tRNA synthase complex-interacting multifunctional protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AIMP2</name>
        <name evidence="8" type="ORF">CEXT_538801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005090">
        <property type="protein sequence ID" value="GIX99738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PU84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042360">
        <property type="entry name" value="AIMP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041503">
        <property type="entry name" value="AIMP2_thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13438">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13438:SF2">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18569">
        <property type="entry name" value="Thioredoxin_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIMP2 thioredoxin-like" evidence="7">
        <location>
            <begin position="91"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX99738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="292" mass="33167" checksum="CD63C1ECCC0C37EE" modified="2024-11-27" version="1">MTANGPLMYHVSPLYDFTSDIVLPTCMYKVNNMLSSKIPSEFNDQGNSKSLDLVELEESQLNILQELENLKEKVLKLKKEFGVEYHSNVEKFQDIVIKANPKCPPLSIWVLYHLFSQSTATCLATYLHSSLKTIPEDVRHLQNASSSESCNISLTVIWRDGKKDHEMMIDPIHQSTIEGEVNIARYLSRLLCFTDENDALLSTQIDNWLEVVHSSIIHGNNKDRQGALRSLNAHFGKNSFLVGDSFTIADIVMWSALIQTKLHQNLPTNAEKWFKSLLNIDLFKKCNGLVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5W4</accession>
    <name>A0AAV4Q5W4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_495091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005626">
        <property type="protein sequence ID" value="GIY03819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5W4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14474" checksum="593BD7E78E176F04" modified="2024-11-27" version="1">MKTTPLPMKAGGSTIDSRGVDGEGWMWQRSCEMERLICCNLHVQCGRRAPRFGQRRANDSFFSKTTPTVIRPNYRLKTRLRKGFNKVFHADFAFDSSRITPLPSLHPFSSSSPCFFLVGVGKVKGGGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8H7</accession>
    <name>A0AAV4Q8H7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005738">
        <property type="protein sequence ID" value="GIY04629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8H7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13324" checksum="D430B6C4BF43CF1A" modified="2024-11-27" version="1">MITMPECTNDRNCFCRFVCIIHQFVIGRAGFRPLIKCSPVRPVVISDRDTIILPPTSLRGFGGFEWRDIFASNIHPCDETLNVVEMLLMVNCYEEKLLSHYTLFCYVYPQRWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QKK0</accession>
    <name>A0AAV4QKK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_110688_1</name>
        <name evidence="2" type="ORF">CEXT_576251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006272">
        <property type="protein sequence ID" value="GIY08621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QKK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22751" checksum="BC6ECE27C28A9ED6" modified="2024-11-27" version="1">MTEHLRRGNSVKFGLQLEQKRFFKKKNFILRKQMESIRLLSSIQSLSVTQISPLPTKGPDIIGLQPRYQVGDEAQAHHVTHLPPRKTKEGLQWIELRLVFSMAGKYIRKGGLKLQCLAEVFLTYARSHHELVIGERLSGPGPQNAPNVIPSRRRPRVSGSSSRYDVGDLVDINCTSAKESTPPILRWFINDREDKISMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTH5</accession>
    <name>A0AAV4QTH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Myb-related protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MYBL2</name>
        <name evidence="5" type="ORF">CEXT_58961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006755">
        <property type="protein sequence ID" value="GIY12196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF30">
        <property type="entry name" value="MYB-RELATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043629745" evidence="2">
        <location>
            <begin position="26"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="28"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="67"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="110"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="110"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY12196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17231" checksum="9FEAAB24BDB0FCA3" modified="2024-11-27" version="1">MLVIALFVLKASLFLVKHNLPIASANHDERLRVLVGTYGEGQWEKVASHFPDRSDVMCQQRWYKVLNPELVKGPWTKEEDEKVIELVKNMVLKKMDSDCKISGRWHNHLNPSIKKTAWTLEEERLICHFHEMWGNQWSKIAKELPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVC6</accession>
    <name>A0AAV4QVC6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endoplasmic reticulum junction formation protein lunapark</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lnpkb</name>
        <name evidence="5" type="ORF">CEXT_412181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Plays a role in determining ER morphology.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the lunapark family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006735">
        <property type="protein sequence ID" value="GIY12065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098826">
        <property type="term" value="C:endoplasmic reticulum tubular network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071788">
        <property type="term" value="P:endoplasmic reticulum tubular network maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903373">
        <property type="term" value="P:positive regulation of endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040115">
        <property type="entry name" value="Lnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019273">
        <property type="entry name" value="Lunapark_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166:SF12">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10058">
        <property type="entry name" value="Zn_ribbon_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Lunapark zinc ribbon" evidence="4">
        <location>
            <begin position="96"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY12065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="29294" checksum="1CC3F44D1F76703E" modified="2024-11-27" version="1">MLKSSTFGTLYFIILFSELRRRNVSPRGASPIPLGSPGQTLTINSAGYPNSFQFFSGKSPTNPPYPTAFFQRGGQRFVRPPVPPMPRPVLPRERTFTDRLVDYLVGDGPSNRYALICRQCQSHNGMALKEEFEFVAFRCCYCFQFNPPRNQQPAAPRLTLPAPPPAITEGPSSEVSTSSAINEVLPSEVSTSSDETEIESVSDVESSIHKSDEKEAADNIKDASNKRLSVSSENEIQANLVEDRPYSYSADSDADIQKFPNIDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXZ9</accession>
    <name>A0AAV4QXZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_332481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006905">
        <property type="protein sequence ID" value="GIY13209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13810" checksum="BB592CD48358C1DB" modified="2024-11-27" version="1">MTPCTYHKREDTFFRKSPSFRKSTPVIWGAQGQKGRAALSLTKKGRLEDTCARGFIVNACCPPSETKDAVLCMVLWKYLLTLTFTKCIPRRSNRWMFIFCNSWKTYKYCVRRICKFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3Y1</accession>
    <name>A0AAV4R3Y1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DNA topoisomerase 2-binding protein 1-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">topbp1-A</name>
        <name evidence="11" type="ORF">CEXT_296681</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007453">
        <property type="protein sequence ID" value="GIY17018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17731">
        <property type="entry name" value="BRCT_TopBP1_rpt2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17718">
        <property type="entry name" value="BRCT_TopBP1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18434">
        <property type="entry name" value="BRCT_TopBP1_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17727">
        <property type="entry name" value="BRCT_TopBP1_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17738">
        <property type="entry name" value="BRCT_TopBP1_rpt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17728">
        <property type="entry name" value="BRCT_TopBP1_rpt8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000018">
        <property type="entry name" value="DNA topoisomerase 2-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000021">
        <property type="entry name" value="DNA topoisomerase II binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059215">
        <property type="entry name" value="BRCT2_TopBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057595">
        <property type="entry name" value="TopB1_SLF1_BRCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049542">
        <property type="entry name" value="TopBP1-like_BRCT0"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049936">
        <property type="entry name" value="TopBP1_BRCT_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561">
        <property type="entry name" value="DNA REPLICATION REGULATOR DPB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13561:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 2-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23294">
        <property type="entry name" value="BRCT_TopB1_SLF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21298">
        <property type="entry name" value="TopBP1_BRCT0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="149"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="277"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="475"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="569"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="901"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="1194"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1053"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1094"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1416"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1065"/>
            <end position="1075"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY17018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1436" mass="161357" checksum="D30C50FEFDFB4C54" modified="2024-11-27" version="1">MSLDFLIQETEEIFKIYFRFKMSESKDASKYDVCFVQTNNSNEPTENLKRAFEAMDSNQLEPTWITAEECFQVSRKEPKLYIIDPFEGEVFEHLKTANCRLVGPLCILYCLQHGDILPKRPNPVYSVSMRKITVSCSNISNDLREDLRHKIELMGGLVVTVSQLSVDERSTVQSLIEQNGGSYLAPLKANKTTHLVLTEPVGDKYRYAKNWKIYSQKIYSNRDLTCSELPLVDCSAITNISTVTHLDETVRSETSIACRKGSWVPALESFDLSSLPKYGQFLDGCKIFLTGFSSIHLDKLRKIVNAGGGMRFNMYSESVTHVVCGDLDDEFLQTYNSCPVGPFVVSVNWLLECCKTEILQDEKPFLCVESGLLTPEKEIPEIKSNNMSQTSKPQFKNEAVPYQNLTDIFIQYVREECDSNNQDKNSNNSSVAKQFVGDNKEEPGSQAKSNSEETNIDNQEVDVVDLADDDDPTSSSMQLFAGLKFVVVGFGEKDTEILAKMIEDHSGCVFSNDITFCKADIAIVPILWNDYITHAANIVTNCWLQKCIEESRIYEFDENELFKPIVIPPGKKPFESFVISVSQYTGTERDCLMHLAEVLGATCQEYFVRKANRSRGILSNTHLVVATPKGSKYEASKKWKIPAVTKQWVLDAAKSGSIPPVNEYLVDACKPLQSNTDISNKISLPDKEEKENINHIDVKQVSAESNVAKTRQSLSKSRRSSEVIVVKEDLNRTDIQQIPPLSKSLRDSKLNADCKRTNVEDLNLSHLNKELDLEFAKPFNHTSTSTPQRNVIELHNENKKELESPMLSKTETTFNESLNLDQSYKYKFQVSGLLKDLDNSASQEHSITASAKRKSLPIEELFGRNLASALRGVNNKMLLPHVGKLDFDKSNLSDICPKTSDTSAVMKGVILCVAKKLANIQNELNEIVISMGGEYLWSYDSSCTHFVFTGKANDLSKEFREARSQGKKIVCPEWLYACREQDAIVDENLYPHTLKLNMSLTGEIAIVKSATTEKDVAVSDKEQPTETTAAAPANIDVADFNQQLNDLLVAAKSAKRRQSRRTLNSVSSSPSSEVSPLHKLQQKHIPHPLIKPVQQEENGTEEQDTGSQSQSYPVVWDDPTGRQEREIVAALWCSNGALENIQTTKPSTSAGSSKRSSTNASLTMLSNDNNFDEVFIGPKKTNTDLQEKTRVRKFMFTNIPDPKKIKFIEIIKELGGEVSDEKAFDITCTHLILEKPIKNEKLLSSVASGKWVLHSQYLTACENQKKFIAEEDFEWGGPCTCEFVASFPNNMKKIANSPFRWRVKLNGQTEIKGAFHNWIVLVIADDKTKQSTYTKILEAGGGDVVPSEAGIQNLERLSHVIVDMKKRSLSQIDLCPYVNNKVKCVRPEYLAFYLIEDPEPDIENFIIPEAKNLSEQTSKRRTLSISTRGSKKSRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5J5</accession>
    <name>A0AAV4R5J5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_608431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007357">
        <property type="protein sequence ID" value="GIY16291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5J5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="36" mass="4128" checksum="56563770190DAD83" modified="2024-11-27" version="1" fragment="single">MPRLPATGNPRSLDDIPRRRHFLTERALAIGWTTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGI4</accession>
    <name>A0AAV4RGI4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_575071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007738">
        <property type="protein sequence ID" value="GIY19325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13764" checksum="A0360B6E8CACF3E8" modified="2024-11-27" version="1">MTLLPSVWPVTTAWPDGPTNTPEVTSCWCCSCWFMAPHPEDWKKKPNLFCYRSCSFQSSNFSSAKVESSSLFVKKFSFAVLVRVSEASVFGSGSAVCRYELLCGLVKKRRRHRLRCNLITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV51</accession>
    <name>A0AAV4RV51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein roadkill</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rdx_0</name>
        <name evidence="2" type="ORF">CEXT_414811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008375">
        <property type="protein sequence ID" value="GIY24266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="273"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="417" mass="47802" checksum="B258EBB120B4D850" modified="2024-11-27" version="1">MAFNIMRQDGSFTFTWTLKDIDFCFSNRNYVRSPTFSAESLRGTIWEGFSAISHLGVESVSCLWKIKSFSKSPTFISSYPLLPDTSHKLKMQGISWKLGSVQSIAKTTYLNIQIIQDSVSINSSVHVAGRISIIGKGNKEIITSESRHVFCANGENKTWNFPIPISQDSKVLKRMLFLGSDELSLQCEFYFSVLVNESMEYRMLPAEYQNICHDANDETLLRVRFPSIEIDKSSEEAYGSEMFTIDKPETSHEGCIDSLVEDLKNLYIKKNYCDVVLRADGMSFPTHKRILCSRSPIFRAHVQRQFERAGKKKKSTLLVCIRSPLNKFLLFLYSAKLEDLQWDEAIQLLYAAKKYQVPSLQVECCTFMKSHLSISNVCEAFDEAFKYQSTELKTACEEFTIKNAVKVFASKEWKEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV62</accession>
    <name>A0AAV4RV62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_671461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008574">
        <property type="protein sequence ID" value="GIY25768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12699" checksum="B054B46FA6AB2135" modified="2024-11-27" version="1">MGYSIYFENLPPITLSLNADNRMPFPIELQKYSRIPVQYLTETHFKYVVLFHNGSTTLLNNVQKILFKFVTIFSTTNYGVWEKLSIDLQTCIESVSKPAMDRVLNGIEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWT3</accession>
    <name>A0AAV4RWT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_591101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008378">
        <property type="protein sequence ID" value="GIY24303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8617" checksum="2754ED6FDC9789FA" modified="2024-11-27" version="1">MESLVPSPVTASEENKGNVPVQANGSPYDFRMFEGEMYLEELSRHICCQLEDAIPSLTMEFQLLILGELLSLDILGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S5M9</accession>
    <name>A0AAV4S5M9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_537221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008807">
        <property type="protein sequence ID" value="GIY27348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S5M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13228" checksum="CB7B8477FC70F34E" modified="2024-11-27" version="1">MECVGVGPLPCVSRRRQGQSWPLRPRASSFLEENPHSFLMPPSSFTKIRGLLMEGPCEFFRGCLSCFDVSLRRISPVSQVVFQEYLRIFHSPQWISLGRKIKYEPILSMLGLPVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S5U5</accession>
    <name>A0AAV4S5U5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_410241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009062">
        <property type="protein sequence ID" value="GIY29374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S5U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12811" checksum="D74975429B57FE6A" modified="2024-11-27" version="1">MWGKVDPSMAGNWRTDHSSFLASIHESGFKLVSFKIEISSVPSSHGNREVISQNGRTLSFVQMLWLMESFMVPRILKVRSAPVTLCKQSNAESFLSLKTRQKRISKSNISPSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9N3</accession>
    <name>A0AAV4S9N3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_752551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009055">
        <property type="protein sequence ID" value="GIY29336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9N3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="58" mass="6158" checksum="FA387EF0480AAA20" modified="2024-11-27" version="1" fragment="single">MASVDGKPNSSYHVRALYSFCPVGAFNSSFHEGGMPFSLETGTKAGSTENTGNTYDHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDX2</accession>
    <name>A0AAV4SDX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_408401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009388">
        <property type="protein sequence ID" value="GIY31529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10398" checksum="E91C64E53F63BA4E" modified="2024-11-27" version="1">MGPREFDRKIHAENDETCYHWSIICSFVDKSRNICCNFSRLLYHFHEFLQKMEILEPSHLRMTLSPNPSNNRALRDKVTPSRISTTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFN7</accession>
    <name>A0AAV4SFN7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_453981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009354">
        <property type="protein sequence ID" value="GIY31287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12990" checksum="8CBDEEF758DADC30" modified="2024-11-27" version="1">MMSLSFCRHLMEWGGPLGNATARTVGRNARRKMPNALFLCVPKMESAFWWVSLGREFSIRFIASLRMSLRRRGAQSILKLFCIIQRHLNFFAFSVLRKFSCFRTGYSFIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHY0</accession>
    <name>A0AAV4SHY0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_720311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009572">
        <property type="protein sequence ID" value="GIY32969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8379" checksum="01084AF0FC2E1FEF" modified="2024-11-27" version="1">MHEYRSRSGSLLISLCRNSMDLRLCKRCASEIVEAKEKPTMDLHLHLLLLGTEGKVHFHRYGLRTKRGEELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SRZ6</accession>
    <name>A0AAV4SRZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009958">
        <property type="protein sequence ID" value="GIY35769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SRZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9827" checksum="75E5AC185EE830ED" modified="2024-11-27" version="1">MMDISLFLEFCCCRDVTGDDGYFLSVRPCEIGVGCITRQFDQVSVEVQDNEFQDNEFVSDVIFELDEMCRYQLSVAKGDGESHGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SV17</accession>
    <name>A0AAV4SV17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor CP2-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TFCP2L1</name>
        <name evidence="4" type="ORF">CEXT_460692</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010127">
        <property type="protein sequence ID" value="GIY37139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SV17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007604">
        <property type="entry name" value="CP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040167">
        <property type="entry name" value="TF_CP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037:SF21">
        <property type="entry name" value="GEMINI, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037">
        <property type="entry name" value="TRANSCRIPTION FACTOR CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04516">
        <property type="entry name" value="CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51968">
        <property type="entry name" value="GRH_CP2_DB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043427894" evidence="2">
        <location>
            <begin position="29"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Grh/CP2 DB" evidence="3">
        <location>
            <begin position="128"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY37139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="311" mass="35264" checksum="88E13B0AABD86799" modified="2024-11-27" version="1">MESFITSMLIYNLNHILLICLATHGSEKCQIECYPVSIVHGKKIRYSQLTDIDCTNSVKRFCINKDKEHSENFQVTRCRPHSLSAPELRTTSSHFYSSGSVINTILSQVVQLPVIPPLQSVDQGNQGPPPPFHCVLLAQTSISTKINEETLTYLNQVLSFQPPSKLCCPVSVSASEVEQFTSIQSDVQENGIYIGSWTKVPLVCHSAVTLKIISIASQPYEVKIKKNAIFPCERNMLFKSVIHIGFQERRLQYMEKEQLKEWQSQRYGERILEIDVPLSYGMLEAVNKPTNINECEIVWDPAHDIGVFFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVG6</accession>
    <name>A0AAV4SVG6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_455611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010169">
        <property type="protein sequence ID" value="GIY37387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="27" mass="3200" checksum="1C9EDC5737309855" modified="2024-11-27" version="1" fragment="single">QPGVLDLKGKAKWEAWNGKKRYGTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVI3</accession>
    <name>A0AAV4SVI3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_322091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010171">
        <property type="protein sequence ID" value="GIY37402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="40" mass="4829" checksum="8A4915383632B155" modified="2024-11-27" version="1" fragment="single">NSKSILRTTRRYEMLYLWFRSRMSSGTGLRNLRFAVLVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2C1</accession>
    <name>A0AAV4T2C1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_693151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010614">
        <property type="protein sequence ID" value="GIY40455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2C1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8751" checksum="68C49A8D870E2143" modified="2024-11-27" version="1">MKSEASNTFENIKPRVLCTTIDQVLGCKSILVPVFSSLHWPEGSEQIRFGTKLRQSNLFQAWKPYFFTQENLQNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8E7</accession>
    <name>A0AAV4T8E7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_596891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010861">
        <property type="protein sequence ID" value="GIY42540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8E7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20236" checksum="57033B2F462F5F17" modified="2024-11-27" version="1">MSSELENMFGLFIVKRAASKKKNKKRSKGGTQLQLFHFDGAQENTLVFQGFESIRQITQFGLTLSLRSTQEDGEIWKTCLDCSSLGPCFLSSGSHSKISASKKKKNKRSKVETQLEIFHFDGALEKTLVFQGLESIGQITQFGLTLSPRCTQEDSEIWKTCLDCSSRGLCFRSSGSPFKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T935</accession>
    <name>A0AAV4T935_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_306251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010765">
        <property type="protein sequence ID" value="GIY41846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T935"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13508" checksum="DB83AD7C663B331C" modified="2024-11-27" version="1">MLECSAPPFRLHVGLLTLKALPYTLDSGLLVLLYCRTFQKLITLEPETILFLEGKEKKNGLFSARKRFGVFLSGERFLADVFRGSFSLGKFSSKTFSSKTIFYLKINDIFYSVRTIYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCJ0</accession>
    <name>A0AAV4TCJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tumor differentially expressed protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_300651</name>
        <name evidence="3" type="ORF">CEXT_367691</name>
        <name evidence="1" type="ORF">CEXT_802781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019386">
        <property type="protein sequence ID" value="GIX67231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01005446">
        <property type="protein sequence ID" value="GIY02446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01010946">
        <property type="protein sequence ID" value="GIY43191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY43191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15209" checksum="1B720CCCBB51419F" modified="2024-11-27" version="1">MQQSSDLRERALLLDQNQSGLSQGPSSVVTLYNFGLIARARPGDVSFKCLPYQLSMVGYAPTMVVTGDGESGTKVRGSKAIRYRPSSNHKRCQPAIRLCSSNDTPGSFRETKACGFRGSMVAKLKLKGIDGRAPPEMEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKT6</accession>
    <name>A0AAV4TKT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAM and SH3 domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Sash1</name>
        <name evidence="2" type="ORF">CEXT_169311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011473">
        <property type="protein sequence ID" value="GIY46735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="210" mass="23104" checksum="6A68AE4C1F677F6E" modified="2024-11-27" version="1">MPNECSNINGNAFQSQHIYYEPPEEFEFDVTSSLLPDTAGEVIVHYLPTSPDSKHCNPSKDNPSDTTPSQISNNNNGDGDSCKEEQQKEAEQRAYTKEEFTSAILARTHHEELRRSCPGALDGFAVAEEDQLDMGESGVAVVRDTLAPNGQSLIAGEGREACDCERRCSNPKHSHDCKSGDFGVSPILDRRNKGVLGRLRNFALPHLWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TN38</accession>
    <name>A0AAV4TN38_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pyridoxal kinase</fullName>
            <ecNumber evidence="2">2.7.1.35</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pyridoxine kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PDXK_0</name>
        <name evidence="8" type="ORF">CEXT_399131</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.35" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01011584">
        <property type="protein sequence ID" value="GIY47479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TN38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534:SF2">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY47479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13495" checksum="392DF9AD6CB7689F" modified="2024-11-27" version="1" fragment="single">LLTGIKIKSRTDIMEVMKTFHQNGVKTVVLSSVQLETSEKLYLFGSSILEGHSRNLLGWLKTDGDLKASCEKVVNSLQCVLRRTIDFASKKGKNVATMELQLVQSKLDIENPSIDLKCLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSJ2</accession>
    <name>A0AAV4TSJ2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mutator-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_672681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011645">
        <property type="protein sequence ID" value="GIY47897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049012">
        <property type="entry name" value="Mutator_transp_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20700">
        <property type="entry name" value="Mutator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mutator-like transposase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8281" checksum="5173F184616E2CA8" modified="2024-11-27" version="1">MCNAAKEVAETFNRDECVVFVDGTWQHRGHTSLNGCVAVLSIDTGKVLDLEVMSSYCPTCRKLQNCIRMLNMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TT17</accession>
    <name>A0AAV4TT17_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_654461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011820">
        <property type="protein sequence ID" value="GIY49320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TT17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11942" checksum="576E6F545B786E99" modified="2024-11-27" version="1">MAKKKQHVFPLYRNVIYIFYHRCLAKEHIKRRDLNPGLFIRILFPAFEFYESINPERLRFLSGISDKTDYLFRERKDPNKRENLEINELCFSEAGALCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9L9</accession>
    <name>A0AAV4U9L9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_230331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012515">
        <property type="protein sequence ID" value="GIY54448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043685869" description="Reverse transcriptase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8647" checksum="9C819DDB42E6DA8F" modified="2024-11-27" version="1">MHAPCDVTLCLAWLDVTNAFGAVPLQAIDDALRAAQAGDTLRNLVNFVYGTVIFSRPKGCRTQSASEQGSNKVVPQWPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJC4</accession>
    <name>A0AAV4UJC4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-carbonic anhydrase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_589091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012967">
        <property type="protein sequence ID" value="GIY57826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="12433" checksum="03A5002BE577B82C" modified="2024-11-27" version="1">MPVQMRYLRKTIFKYICCSRRHNADDALKYVFPHFASPDFWGLLNPEWTMCTKGRRQSPVDLDPDQILFDPFLRPLNVSKPQDERDVTEIFLVKLVLCAEIKCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UL32</accession>
    <name>A0AAV4UL32_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_158691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013045">
        <property type="protein sequence ID" value="GIY58294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UL32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="4"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY58294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24233" checksum="E2C224CFAC7DF1FB" modified="2024-11-27" version="1">MSSTNKNAADAKLNSLLYEFLELYKGRTGCAIVLISGDSDFANILNTLRFRYNIYVNLICKNNARHSLVEASHSCVFYEDFIKRLPARSLADDTEHLIIVSNFPNNMKKKEVKDALSSRLKSVNCRVKNINEISAEIVLPDDCARDRALKLLKNFEMGGNEIKTECSDKKKESISIGISKPARPINPKNKYTVEDKSKYDEKNVSKFFLEERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UN18</accession>
    <name>A0AAV4UN18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Katanin p80 WD40 repeat-containing subunit B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">KATNB1_1</name>
        <name evidence="5" type="ORF">CEXT_200081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013163">
        <property type="protein sequence ID" value="GIY59116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UN18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028021">
        <property type="entry name" value="Katanin_C-terminal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13925">
        <property type="entry name" value="Katanin_con80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Katanin p80 subunit C-terminal" evidence="4">
        <location>
            <begin position="14"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY59116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7975" checksum="475F6A979C30BCD5" modified="2024-11-27" version="1">MRTFRNHGFSSVVKTRSSWTLDMCQLLLPVICDLLKSKYETYITIGCMTLKLIMKNFSQVIKIQHYCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQK2</accession>
    <name>A0AAV4UQK2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013262">
        <property type="protein sequence ID" value="GIY60016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="25225" checksum="192AE14C6B045003" modified="2024-11-27" version="1">MNTPGTAIRYPVTWSLWNLDCLSDPLDCIPIYPTRLSTQHIPLIFFLPCLESDDSYLAFRNITPAASHHYLIIPKEHIRDAVDLKPHHIPMRMLEKIIHKKHLTFNVKRKDLPTKPVSFAVYQMEAIAQGVLRQQGAASRNKRQFKRLNNDRENILSDYVAGKSSFPVRSNTTQSKTRWATTGPVHLRAAPTPARNRPRGRAFHEGQDYIPAGHQVVPHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1Y0</accession>
    <name>A0AAV4V1Y0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Polyadenylate-binding protein</fullName>
            <shortName evidence="7">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Pabpc1</name>
        <name evidence="10" type="ORF">CEXT_580861</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013815">
        <property type="protein sequence ID" value="GIY64014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1Y0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.10:FF:000001">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000021">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000042">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="11"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="99"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="192"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="292"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="9">
        <location>
            <begin position="562"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY64014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="651" mass="72195" checksum="3EA407AB437AEF5A" modified="2024-11-27" version="1">MNNTGANYPIASLYIGDLELDVTEAMLFEKFSTAGPVLSIRVCRDLVTRRSLGYAYVNFQQPVDAERALDTMNFDIVKGRPIRIMWSQRDPSLRKSGVGNVFIKNLDKTIDNKAMYDTFSAFGNILSCKVATDEEGNSKGYGFVHFETEEAANNAISKVNGMLLNGRKVFVGKFVPRKERERLMGEKARLFMNVYIKNFGEDLNDDKLKEMFEKYGKITSAKDEAGKVKGFGFVSFEEPENAEKAVEELNGKEFNGRTLYVGRAQKKSERVAELKRRFDMMKMERLNRYQGVNLYVKNLDDAIDDDKLRKEFSPFGTITSAKVMTDPNGRSRGFGFVCFSSPEEATKAVTEMNGRIVVSKPLYVALAQRKEDRKAHLASQYMQRMAGMRMQHLGQMFNPTSAGYFVPTLQQGQRNYFPQMPQVRATPRWPQNPQMRPGAAPTAAFQAMQSAPFARAGTRPSVASQNPGMRTNMSARPITGQQATAAAAAAAATGTRVTAMGPTSVPAARPAGMASANVNAGRSPAYKYTANMRNPPQPQAVPQAGQLAQQSMPQQAVHIQGQEPLTASMLAEANAQEQKQMLGERLFPIIHRWYNDLAGKITGMLLEIDNAELLHMLEHHESLKAKVEEAVAVLQAHHAKESTPAGIKKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V495</accession>
    <name>A0AAV4V495_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UPF0547 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_266258_1</name>
        <name evidence="5" type="ORF">CEXT_88991</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0547 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013955">
        <property type="protein sequence ID" value="GIY65062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V495"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040246">
        <property type="entry name" value="C16orf87-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018886">
        <property type="entry name" value="UPF0547"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31101">
        <property type="entry name" value="UPF0547 PROTEIN C16ORF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10571">
        <property type="entry name" value="UPF0547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0547" evidence="4">
        <location>
            <begin position="4"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY65062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19784" checksum="C0416031B0B7A4A4" modified="2024-11-27" version="1">MVTKQCPNCQQHVPVACKACPCGHIFFVARRAVSIHKTGGTDEGEVKRRRTERTKRERPDYFQSLQVDNELKKMKRQKKSNKKDDNGEKDGDGSNSEDGSEATNRARSSLSTKNKKRGRPKKNFSQDKSESKTDKDEEVDMFAHLSKEREEQFGVILSEINRKMMQQQLSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V634</accession>
    <name>A0AAV4V634_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_687291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013995">
        <property type="protein sequence ID" value="GIY65473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V634"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15661" checksum="8E7DEA3BC09A1ED0" modified="2024-11-27" version="1">MESRLNYTEDCAPCRNRRSLPQDSGESERNRTLTGTGRRLQGFTKTRGSGQKEDANEKKPVENSENPLLLVVPFVTLVDIGRTTPGQCSKNRRGWRKRMSRVVMSTLEKSHEVVHRISCYRVGMSVRQYQNQSFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VET3</accession>
    <name>A0AAV4VET3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_791991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014334">
        <property type="protein sequence ID" value="GIY68149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VET3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10495" checksum="B0D781F1DE219C4D" modified="2024-11-27" version="1">MEIPFVVLLQMRSVNSEIQKDVPNCSRTRNQLHRPTGLRWGVKQTATGTNSVRISRIPVSPETNPMKMFRIKVPPQTNPMRVFRITPRKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMJ8</accession>
    <name>A0AAV4VMJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin domain-containing protein 5 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prtp</name>
        <name evidence="4" type="ORF">CEXT_791251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014761">
        <property type="protein sequence ID" value="GIY71184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF3">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="125"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY71184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="294" mass="33548" checksum="0BE0634CC3F625E8" modified="2024-11-27" version="1">MVKICLGSDLYSDKVLNYDFPTFKQRVGGDKPHFVNFFAPWCGYCKRLKPVWDELAEKYNIDGDRQELVIAKVDCTVETPMCADEGVSGYPSLVYYEVGESKGLKYQGKRDLIGLEDFISNNLRDKSKDSDNNKVVSPENGALVLNDGTFQDTVKNGMHFVKFFAPWCGHCQKMAHAWEELAENFQYDKSVTISKIDCTENKKTCDEFEVKGYPTLLWIINGKKVEKYQGARNLDGFKQFITEMKTAHKNKLDNEEGRIADSKESPNLVVELSQNNFENAISQGVSFVKFFVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VN22</accession>
    <name>A0AAV4VN22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_477571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014784">
        <property type="protein sequence ID" value="GIY71315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VN22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10577" checksum="112F07E10DC7E2E9" modified="2024-11-27" version="1">MESGLVFVDDGIVFKCVRRIPGSANSEDEPVFSTLHSDEDELLNLIDLFRSEEESDDENSSDSTTDPGLVKLTQEKTRKFTDMAMKLHRIKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNW6</accession>
    <name>A0AAV4VNW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_257603_1</name>
        <name evidence="6" type="ORF">CEXT_483751</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014834">
        <property type="protein sequence ID" value="GIY71615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY71615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="429" mass="48581" checksum="29BDA277D3612EE3" modified="2024-11-27" version="1">METNALQELTFVKSCLMLDNPINISDCSYELKQNKTIAIDESAKWSKYSNTFLFFCTFLATFYVGSWSDRLGRKFPMLIPPIGTVIASSINAVLSYYIRWHPAYFLGSSFISGITFGSVGIIATTYGYISDFTHEQSRTKRIAILESMIFIGGTIGIFVAGAFLGHIDYERKLNNFVLLFIFEALLSATVVAYIIFRIPSYSTDNQSSQSPLSFSSLFSLKHVGYSLKTIFRSREDGKRKKILFSLVALCLIYLGTVVQLFLSFLYVKEMGWTFTDYSNFHSMQFAVEGFALVCIFPLLQRFPRIPDHFIGMLGLFSKCIGLTVFGLSVLSSQHDYMIYSCIALYMFSEFPVPALRSMLSKTVSPDEKGKIFAFTTILQNMCYLIAFLIMIYLYCTRRIYVTAYETIEHEDGSITEVCSVVSSEGSVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VP32</accession>
    <name>A0AAV4VP32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_735841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014795">
        <property type="protein sequence ID" value="GIY71374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VP32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8884" checksum="F476CCBB1D64EE8A" modified="2024-11-27" version="1" fragment="single">VRKSVSSRCLRGQERVLEVWLPFKDSVTVWRAKLVLPLMVTLVSVWGSGSYGEQWRSCVFEGLRHVLFSICSRKTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTM6</accession>
    <name>A0AAV4VTM6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tumor protein p53-inducible protein 11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">p53-induced gene 11 protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Trp53i11</name>
        <name evidence="9" type="ORF">CEXT_356111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015073">
        <property type="protein sequence ID" value="GIY73363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028266">
        <property type="entry name" value="TP53I11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31584">
        <property type="entry name" value="TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31584:SF1">
        <property type="entry name" value="TUMOR PROTEIN P53-INDUCIBLE PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14936">
        <property type="entry name" value="p53-inducible11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY73363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="238" mass="27014" checksum="7B89B460377534AB" modified="2024-11-27" version="1">MPASTRQNPNANCSIDARFEQKNAGLKSAYCIIKVGKHSSGDLHSRLKTRKILGVGETDNGDIHRSKISQLLGHNEHLYVKFPRGYWMWHLSVALIFTLLGLNNLFFPENSYDLPRRDETSPQDDLACRFYGCTSLALAFLMWSFWGTMDKGVVRTLLLATALCHALQVLALMTSQWGSLMNWRTLTYLLVRSLLVLPNAYFYRNIGFCGLRMRKSTSFNNLRDCVYNSNSSSNSQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3F7</accession>
    <name>A0AAV4W3F7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_326701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015483">
        <property type="protein sequence ID" value="GIY76414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3F7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="27" mass="3366" checksum="9425746194A41177" modified="2024-11-27" version="1" fragment="single">FPRLRGRQCDEKKQRKIYKDGNDEKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W650</accession>
    <name>A0AAV4W650_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_508741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015619">
        <property type="protein sequence ID" value="GIY77399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W650"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="21285" checksum="CB4175D8AA5863C5" modified="2024-11-27" version="1">MINYWKSFSRIIVYFLRTTKPQSSKSSAERSFHSPRADDFVTANPQNLVCSRLSKPPLEGGKEVLNFPCLYLESPLHATLRTPFVLFHPPPHPHTLELFFFLFFVLVYLTATSTFILLQLEFFAVLFFFFVIGHIVVVCLTTFAVTAIKTIAVIRCGRVLFSIPVELTVWEKKCFQERNRSTLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9J1</accession>
    <name>A0AAV4W9J1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_380371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015893">
        <property type="protein sequence ID" value="GIY79476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="201" mass="22236" checksum="108794FB926DAFEF" modified="2024-11-27" version="1">MCLTQAEIGYAISNDFHPAGAISDIAAPLKSICHFLNTLLQDVASRVNVVSHNAKQLLKDAHQDDVPCVKRLSCSIMTRLVASPSMAYFLNHTASSYRQAGLSEQQCLTAYRMGRQRNGATARPESWGQPATVTGPYSTWRPPLVRLRVSWSAIPRAMLHWEPEAWHRRALQAGNPAPGKNMICPKFCRDAPATWEAPASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFQ5</accession>
    <name>A0AAV4WFQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein split ends</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">spen</name>
        <name evidence="5" type="ORF">CEXT_273531</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016010">
        <property type="protein sequence ID" value="GIY80433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="77"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY80433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="397" mass="45314" checksum="2D1B5B83FA8A294C" modified="2024-11-27" version="1">MGKSPWSKLSAKGTDRYAVVCFKKEIDIKKQGTATSYAFIQYSDIASVVKAMRKLDGENLGANRIKLLGFGKSMPTNCVWLDGVADATDKYLTRHFNRYGIVIYTAVDKERGHALVFYETVEFAQIAVSEMRGRILQERSYRLIFASRECQTAFFDKLEMTGQMMPGDGTHDPGKEEKEEVQNLILEQRVNFLKIVFIHHGMKDHQDHLRKFRGGQRAGFSSRGRGQGFPPRYEVYHDEFGERRHRYNSREESIPDVTMFDGKIERPAKYVENPECPNRKRNKLRNSISDQESHPSLSPPRSCQQSGSTSPVSKERKSLKERFHHRIKSPGSHNSSLVSSPCRDLVSDEMETNCRDSRSKNDIKTDEVMADLSYPSPKSSSEKDCLEKGLSKGETDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJT8</accession>
    <name>A0AAV4WJT8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA-processing factor 40 homolog B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Huntingtin yeast partner C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Huntingtin-interacting protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Prpf40b</name>
        <name evidence="11" type="ORF">CEXT_237392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with the N-terminus of HD.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016204">
        <property type="protein sequence ID" value="GIY82054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000003">
        <property type="entry name" value="Pre-mRNA processing factor 40 homolog A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000002">
        <property type="entry name" value="pre-mRNA-processing factor 40 homolog A isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000102">
        <property type="entry name" value="Pre-mRNA-processing factor 40 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000016">
        <property type="entry name" value="pre-mRNA-processing factor 40 homolog B isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000050">
        <property type="entry name" value="pre-mRNA-processing factor 40 homolog B isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000015">
        <property type="entry name" value="pre-mRNA-processing factor 40 homolog B isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25432">
        <property type="entry name" value="FF_PRPF40A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="10">
        <location>
            <begin position="284"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="10">
        <location>
            <begin position="348"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="10">
        <location>
            <begin position="411"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="10">
        <location>
            <begin position="498"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="10">
        <location>
            <begin position="562"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="68"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="186"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="738"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="325"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="465"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="211"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="738"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="767"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00058987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00063790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00072039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00075613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00080326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY82054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="828" mass="94557" checksum="0126EF8785D29711" modified="2024-11-27" version="1">MRPGGEGMRPPMMMPPSGTPGMPVPGPFPGPGMPGFPMPGFRNMAPVSGMAPPGMFFANIGTTIPTPNVITAPPSSNSTAAPSSPSVNGVAKDSQNDSSATLKQPEKKSNWTEHKAPDGRTYFYNHVTKQSSWEKPDELKTQSELLLSQCPWKEYKSETGRTYYHNIQTKESRWTIPKELEDLKNLVSAKEEEKNSTKTSSPITTPNSNTAIASPSKGNSAGTNSPAVASPLSESSQNVANIQLPTTGAPENVGTPSDQGDTEDREEGTEEETDPNKPIVFKDKKEAIEAFKELLRDKNVPSNATWEQALKLIINDSRYGTLKKLNEKKQAFNAYKTQRSKEEKEEQRLRAKRNKEELEVFLQNCDKMHSSLRYRKAQEIFGDLEVWRAVPDRDRKEVYDDVVFFVAKREKEEAKALRKRNMKVLSGVLDSMTSVTYKTTWAEAQQLLLDNPQFSEDAELLNMDKDDALIVFEEHIRQLEQEEEEEKERERKRIQRQQRKNREAFVRLLNQLHEAGKLTSMSLWVELYPTISADVRFSNMLTQPGSTPLDLFKFYVEELKARFHDEKKIIKELLKEKGFTVEVTTTFEEFATIVSEDKRSATLDAGNVKLTYNSLLEKAEAREKERLKEEARKQRRLENAFRSMLKNAVPAVDSNADWNVIRKQFENEAPFENITVESERVRLYKEYQQTLEEACSHHHNLDLNLKMIIDTKLSVKESTNLDLDLGLRAGLLGLMMRHRKKSRRKEKRRSPTASSTEGESEVDRRNRDKKRKKDSRHRNHSPSHSSSASREEGEVDPASDKRFSESDASEEELEHRRRLLLQQLKLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQY5</accession>
    <name>A0AAV4WQY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_152411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016504">
        <property type="protein sequence ID" value="GIY84335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12422" checksum="5C53AA7F0E4F22B0" modified="2024-11-27" version="1">MGRIQADTPHGSERPGGQVASALAFGIPGFRFESEAAWMFYHTSSQFCTSAKLVTAKQTTAQPSHPQEPGVVGAIADPVSVSTGLHSVQEVWCHRALSCCNVPRSCLVSHSEHLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCP5</accession>
    <name>A0AAV4XCP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_98991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000047">
        <property type="protein sequence ID" value="GIY91740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10802" checksum="AAD8D8AD9914B114" modified="2024-11-27" version="1">MLIASLYDESYTFPSTFRHRKMPICYNIMCQLCIQRHFHTCVCWKLLVIICIKEPITCPSAVITCGGGFVIWSLSTAANCRAPLNVVRQLNYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XE69</accession>
    <name>A0AAV4XE69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_627811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017606">
        <property type="protein sequence ID" value="GIY92953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XE69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14793" checksum="1199D5A035EA1FEB" modified="2024-11-27" version="1">MSQYLFVVKVEVSHRMAAPEPLLKTTCQSGLYVPDAKYTQTVPKGGNEEGGPYTTKGKENNQNKYGKKKKKRRKERQGGGSEVDFLLLYYVPVFLAWSIETGAFSCAPLVIKENSRTGSGLVRASKSQGRTLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFE3</accession>
    <name>A0AAV4XFE3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_200721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000261">
        <property type="protein sequence ID" value="GIY93373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="14859" checksum="31C84D979C41721A" modified="2024-11-27" version="1">MRSNSKAFFINDDVRDDAHGDAHDGDHDDDHDDDHDDHDDAHDGDHGDDGDHDDDGGHDDVRDGDDGHDGGGGDDHDDDGVHGGDGVRGDARDGDDVHDDVHGDAHGGDDDEPLYYQTSHSWQKCTATRCRQQRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP23</accession>
    <name>A0AAV4XP23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-binding cassette sub-family A member 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Abca17_13</name>
        <name evidence="7" type="ORF">CEXT_417471</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018037">
        <property type="protein sequence ID" value="GIY96362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="6">
        <location>
            <begin position="15"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY96362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="17860" checksum="C7ED74A2D0EDDA40" modified="2024-11-27" version="1" fragment="single">MHTALLQHVTSTGGSISLTNAPIPVMDRYMYDMSSTISKILGPIFVPLALGFLSASFTLLPIHERASKAKLLQLMSGVPPAVYWAAMFVWDYAIHCIVCILLIIPYAMFVHYAFFGAHSEAIGTSLLLMLLYGLSAIPFSYLVSFLFKKGNTGRLPLESVSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR51</accession>
    <name>A0AAV4XR51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_725901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018189">
        <property type="protein sequence ID" value="GIY97615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9690" checksum="7FE53506C8DF0D38" modified="2024-11-27" version="1">MQFQLDVDKSRLAFNGTLFIGRGYGSLDVQTRLILLLLSSDYRSVNLLTTSTLACCENLKTGFSSMATDADLLSPGNPPTSERGWSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRF6</accession>
    <name>A0AAV4XRF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_556871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018060">
        <property type="protein sequence ID" value="GIY96541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12301" checksum="BF929DFF9F816174" modified="2024-11-27" version="1">MLGVYEIHLSSYPQIQTNWKSDFIAHLSGSYIVICRFTGQTSFLQYCCGYEHLSNRISSQFVQKWCIILPCVYLTTSFSTVPVKSHLRSSNSFKTMTTLKPIPSSAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRJ1</accession>
    <name>A0AAV4XRJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_534931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018150">
        <property type="protein sequence ID" value="GIY97322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005312">
        <property type="entry name" value="DUF1759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22954:SF3">
        <property type="entry name" value="PROTEIN CBG08539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22954">
        <property type="entry name" value="RETROVIRAL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03564">
        <property type="entry name" value="DUF1759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="23014" checksum="C40C7EF4A9FFAAA1" modified="2024-11-27" version="1">MEHFKKKRTVVRSAFTRLYNAINDVISADGANLTDNFDLLADFDLLGEKYNELFAVIGTKKFGGEIKDWLPFWGQFSKIDSDPNIDEADKLQYLIQVTLPSTRARELVESFPPSKENYHKAVDSLKSRFGQDDLLVEFYVRELLKLTISMNSRDQKVKLPTLYDRIETQLRALESLGVTTEKYAAMLFPLVESYLSEEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVG4</accession>
    <name>A0AAV4XVG4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protocadherin-like wing polarity protein stan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">stan</name>
        <name evidence="9" type="ORF">CEXT_139951</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018390">
        <property type="protein sequence ID" value="GIY99160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032471">
        <property type="entry name" value="AGRL2-4_GAIN_subdom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057244">
        <property type="entry name" value="GAIN_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046338">
        <property type="entry name" value="GAIN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000203">
        <property type="entry name" value="GPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011:SF471">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16489">
        <property type="entry name" value="GAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01825">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00303">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50221">
        <property type="entry name" value="GAIN_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="GAIN-B" evidence="8">
        <location>
            <begin position="238"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="785"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="806"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY99160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="877" mass="98614" checksum="CD3E136C585E3179" modified="2024-11-27" version="1">MRNIESYVFPHYQIDRRKANRFCSELNGWSEPDLFKCTSLSFVKLAEQLTNLQNGLLELNTSLVVAYAHQLQTAVNKTFPLYGNDVLIFSLFFHNIILHEKQKAGLDLSHRQDRYFIKNLVQAADVVLDPIYMDHWNEIAASTGRGIEMIMNSFEEYLRFWELTLFHQLMYGLTLKMRQKYLDVSPFVEFYVNDGTEIPSVIFPKYNNYPIRENVESLSAEIIIPFNSIGIDKFDDSQNTHGGSGKEVAVLGYVIYSTLGQLYHNRLTVQLVYTKHSINSCKHELLVNLMVFCSYHGIPIGVNAPVLTAVVQSINTSENTGQTPGARLRFRIFNSTGTSPQCVFWNHREKRGEWSSEGCEVESYRHDSPYINCSCSHLSSFTVIMEKNHNEFLPSESLVQNVISYLAIITSLILLACTFLVFCLLRGSQTNSNRIHICLVFCIFAAELIFLIALKSRHSLVFQQITLLVFISALKSSLQCKDSVMDFGNLKTLLWLAVILLPIQGSTWVLAILSVNETHTILQYAFSFFLPARRNLYLCWLLCGKQKDSAADPCYVEKISQKKKKYPEMNGIQSALQPSAAYPPSSKIYHRSIGISTSSATSRSTSKTCASHCRTGSEPKLSENQPSTSECDGMTTDKGIYCKHGKYYEQIIRNCDTEQCTESTSSGPKMGVNVFSYPRLPGSRSPLSKTSLSLKMGLNSKDHSLSWGSVDSQKSSPLSAPISSGVRAEFYTPRMGVSGIEKSIHSARDIYADSNSLDSNLHLSSVNKLDFKTGICSSCKSQSLSKDTLSDFSSSDLPQPDSYSKSPHKGHPHENKKRVRLSKEKGFYANDTPSEEESPLNITLKHFQNGSSSNDSNCEYNNQFKRHSKTAPPFGYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWJ9</accession>
    <name>A0AAV4XWJ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chloride channel CLIC-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVEN_258737_1</name>
        <name evidence="9" type="ORF">CEXT_594041</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chloride channel MCLC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018326">
        <property type="protein sequence ID" value="GIY98693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009231">
        <property type="entry name" value="Chloride_chnl_CLIC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34093">
        <property type="entry name" value="CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34093:SF1">
        <property type="entry name" value="CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05934">
        <property type="entry name" value="MCLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831418" description="Chloride channel CLIC-like protein 1" evidence="8">
        <location>
            <begin position="23"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY98693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="635" mass="71744" checksum="A6F6BC43BCE805A4" modified="2024-11-27" version="1">MFPRNTFSFIFLSCFLLPLSLSYLRDENINNLNTEKREKVKQSAEFDSRQEIAENYLNSLAEIKDGWIDPYDMIGQVELKAESKLKPEKDNSDSPEFVNARKESNVIFNEQIMPDLEKVIVPPGKNIVQNTGINSIQYSGPLDLDIDERPIFSDIKGAEIREKPYTTDDKLVNVNKETFGSFSKRPPQISILDSIYLARWMKKLVMKVEQSDLVPSGINFPLDTVGLNNLKELAAAKSIEISELDDLICSMIDQSTVTTEEKFDWSMYTDFAKDFMWPVVVAMSVAVCAYVIYQGFLYRPAFTIMICIVGVSIFWHWMHLYQQRQAFKHAELSSMNIPTECRKNDFGLIEHFQEYIRSFFTSNECAKYYEALMVDPVWEVSFTMAASEAVAAMLFQPLSAASRAVNLALKQLFEGLSIFVIIPVMIFIFLLLIMLCNYRVKLPFFMGALEPHTPPAGSRVEEVKPSKALKIIRDTLCKLLPGSSSEAQGNLPRRSRNQRCIQRCSGQSGAHCEFRSLGSSYRHGNCFPCEACNVIEPAISEEDISIIDSEEDGESDDSRGFQSTHHCCSYCFPEDDMPNMHVDCRVCEDRMNAQNAGNSVQLSSRSSELETGDNEAATNMISDTIPVAAGNILSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1Y2</accession>
    <name>A0AAV4Y1Y2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_522091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001169">
        <property type="protein sequence ID" value="GIZ00539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1Y2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11751" checksum="3D264CE9FB143D96" modified="2024-11-27" version="1">MGLFSIDSTICRAVTTAFYQQPFLVQASFSCNGTILGQQRGNSPLMKIIYISSFDDATRLISFATLVKKINELFTGRICMLMIASDHYVYESKFASKKLTRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2T3</accession>
    <name>A0AAV4Y2T3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_19311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001290">
        <property type="protein sequence ID" value="GIZ01373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2T3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="290" mass="32906" checksum="C8CDB5B38D24B05A" modified="2024-11-27" version="1">MGLIGAKIRQPKITAKEMLKRVIITEWNNISSEETSKLVHSMPKRLTEVLRHNEDILDVQKSVKTENGKETEYFATESHSESSFEVIGQDSSSAESTEKVKENSQITNNEDIPDAQKVRKERRFATESHSESSFEVIGQNSSSAEKAKDSSQIASVEVIQEQITEEFQLSTSEDENKDSEFRESTSEGEIEKSKEIKKYSFEISQDSSSAESTEKVKENSQIASEEVIQEQITEEFQESTSEDENKDSEYRESTRDPSQSTKHSVLEDPGSGHRQILAEISFTVKKKRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5G0</accession>
    <name>A0AAV4Y5G0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_392381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001333">
        <property type="protein sequence ID" value="GIZ01676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5G0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20786" checksum="58FEABCD23E6B03C" modified="2024-11-27" version="1">MAFQGETEIHVPWFNRLRDPVIYLGFFSPSSPLRDPFRKQTKLEIGLRWVTTRMIRHLRPRFESVSGFAEEHFYTGEELCKSLGCNALSQEILFVERKKKPIQSTPGEQCTPSPLPEVIAHHAFVVPRGALRQKKKRKNHSETFPSKLCQALLIFKHDGSAECVTVDRFSGKSFVVRVAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y715</accession>
    <name>A0AAV4Y715_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_154461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018790">
        <property type="protein sequence ID" value="GIZ02279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y715"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14391" checksum="31191FD3B5F32070" modified="2024-11-27" version="1">MDYLLALLSKIGSQIKHLSLDVNDTLHTEEDEIYIEGIFKLCVNLETLKIMGVSRVHENAEACASLSCLKRLCLSDADSTCLDIFFLENCPNLEEMFLSHIILENFLDESETESALKLKNSLPSSYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9H5</accession>
    <name>A0AAV4Y9H5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epidermal growth factor receptor kinase substrate 8-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EPS8L2</name>
        <name evidence="5" type="ORF">CEXT_690781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018904">
        <property type="protein sequence ID" value="GIZ03110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9H5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035023">
        <property type="term" value="P:regulation of Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11764">
        <property type="entry name" value="SH3_Eps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039801">
        <property type="entry name" value="EPS8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055093">
        <property type="entry name" value="EPS8_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035462">
        <property type="entry name" value="Eps8_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12287:SF23">
        <property type="entry name" value="AROUSER, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12287">
        <property type="entry name" value="EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22975">
        <property type="entry name" value="EPS8_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="271"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="143"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ03110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="410" mass="46525" checksum="757A94A6326EFF18" modified="2024-11-27" version="1">MIQRVSSGATTPPRWRATDWRGDASFGRDSNDETSSTSSEKYERDVAILNHCFDDIERFIARLQHAAAAFKELERRQKSRKSKKKDMGDGMLSIRAKPPSEKEFVDILQKFKLSFNLLGALGELRGHLPPRLLRRLGPENPFSEDRAKREEGQRVHEEVDVRHQDFRVSSRQDRYGGGSDYYHSEAKERPVSPMLSSEPPHMSFESRYYDNAPADLPRRHFDRNGAVTPVSELQDVRSDFSADSIDHGAPSEPQLHFERHQKQFLEDLVAKGAHVVQVMYPRTANNDKELTVLRGEYLEVLDDSRKWWKAKNSRGQVAHVPHTIVGRLGEEDSFHNPTYGTRPKDPSSFYPHSEASATTKPVSENGHKEPSSPRPAIPINPAPADAFLYARARKVNSDTSEAALRAVYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBQ6</accession>
    <name>A0AAV4YBQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_115271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018945">
        <property type="protein sequence ID" value="GIZ03426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16798" checksum="ADD2671F82814353" modified="2024-11-27" version="1">MGPMNTIPARIVAPEDACVTMHVYHFSIEENAPSTRRWLKRYASKDERRGMWFGLDLNLKPGIPKAEHEMWVAVKGDMHVTFFESCGLPVSEIKIHVLAECPKYEMLPTPQLALAKRCMIHLCGDDYLCSKRVAYIFCSVSREPRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBX9</accession>
    <name>A0AAV4YBX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_11791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019085">
        <property type="protein sequence ID" value="GIZ04429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="21380" checksum="32BC02CC13DE090D" modified="2024-11-27" version="1">MGAIKADIFGSRHQQGKTFGVIVCVNKAHPRGDFHPTRGEGLEPLIKGVRNGGLLATLRDATVPEPRWLVYGSRLREGSQSHKGNRTACLSSAPNHKYERRKNKVERRKKAVFPKSANSIPSAQYDWNGCHLDDRICERGPQLGDRQTPSMSNKWRQSRPDIHDIRRKTFGGIVCVNKANPGGDFHPHVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCU9</accession>
    <name>A0AAV4YCU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_631331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001685">
        <property type="protein sequence ID" value="GIZ04045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11579" checksum="B55C5F059B44928E" modified="2024-11-27" version="1">MESQWVAFNLQQTLFRSPCLYAMGDVPMPRNWGASQQFGLGEARWGNEGQNLWKKNIPPPCTPEENVMRRLQTGADAMKPRATVIYFLVPFSEKVQDTRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M447</accession>
    <name>A0AAV4M447_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_367881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001852">
        <property type="protein sequence ID" value="GIX67138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M447"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15600" checksum="008F25B254DCCEE8" modified="2024-11-27" version="1">MNNLFVDSRLSPPGNISQIDKAAGSGIEDTMLISNTTPQGGLRIHFLCFSPAFPPRGHVLQDSSGHFISSFKNQLSLPSLSNHNAKHAPVLSRTLSLGCWRCSFEWGKIQLFCSKITHSRWFILIRIFLSLSMSKYMFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6B2</accession>
    <name>A0AAV4M6B2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Otoferlin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Otof_5</name>
        <name evidence="7" type="ORF">CEXT_25921</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001886">
        <property type="protein sequence ID" value="GIX67549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6B2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037721">
        <property type="entry name" value="Ferlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546">
        <property type="entry name" value="FER-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546:SF60">
        <property type="entry name" value="MISFIRE, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="C2" evidence="6">
        <location>
            <begin position="20"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX67549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="420" mass="47989" checksum="82C8DC6B325A9FE3" modified="2024-11-27" version="1">MSKQNVFFQVYEKGRSLKLKVESLFEEDEPEPGTESQFAVLRVKVHRAEGLPNLTRGLLSHFKKRYAVEEGDFIDPCVHVFFAGLKGCTTRKSKQRVPCGDEQIVFTTKFPLPLGPIVVQVRDDDFMVNNDIGTVAIPLKRYPARMIMVVDGRRDRDRRRKCLFKGVCSGRAHITCAGGNALVNNVFFTLATEVDLGNDRLRCGVFLFGCVHDASIIDRTLSEMKDIRFSLQMGLKGRETVDGELDDNNATPFISPLPMDKRYVYAPYEDTKPCMWLKGIWPDDRKRMFVSNILWKMGHKLKECLTRIQKPSSTVHPEDESSNNNYLLDLENIAMKYDESNADLINYSNFRRCYLKVLIEYCNMYLSKTKLDHERAGIFLSDMEDIVRVCDTARKASSKNYAGRCLGQTQVPALQNEVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6G3</accession>
    <name>A0AAV4M6G3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_611021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019363">
        <property type="protein sequence ID" value="GIX67001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6G3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16238" checksum="2B9E946E5F025636" modified="2024-11-27" version="1">MGLYGEPNQTKSETSLFGGLGSISSTSVAAQNMIFSNGLFYTAEPTKSKEKEKNSVKKKKKKRRRKRWSRGPTVLKYHPYIFPSLATVANLKGIDFGTDVVLPVPPIDGAEDCCGTLEIPTGRTGRSQKSEQIHTGLSSVSEGRTEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBI4</accession>
    <name>A0AAV4MBI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyadenylate-binding protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PAB3</name>
        <name evidence="5" type="ORF">CEXT_659821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002060">
        <property type="protein sequence ID" value="GIX69512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="95"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="193"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX69512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="297" mass="34121" checksum="FFB582ED6FA33257" modified="2024-11-27" version="1">MTTMICIDNLYPKVDVTDLCNVFGKYGRILSAGIDYDKNLASLCRGYVCFHDEISAEIAAKEMNGKKKLGNPVHVKKGNYKTKKHHCEVSKIDESKLFVSNLDLNWDDCDLIKEFQIFGEIDDLKISCTDGKSNGYGFVKFVEPSSAKEAIKALNGKMIREKEIKVETFVPWELREEVWQSPEFAKNRNVQLNNLHVKNLQKDVTEDELNKLFCSFGKIISTKIATDNTGQSKGFGFVCFRNEKDAAEAKEKMDNFNYKSKNLQVSYHQKKESRQKYLHVIKTDPQIRRFEQGQESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCM0</accession>
    <name>A0AAV4MCM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpoA_1</name>
        <name evidence="2" type="ORF">CEXT_786811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019501">
        <property type="protein sequence ID" value="GIX68549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.20">
        <property type="entry name" value="Vitellinogen, superhelical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011030">
        <property type="entry name" value="Lipovitellin_superhlx_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050733">
        <property type="entry name" value="Vitellogenin/Apolipophorin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345:SF15">
        <property type="entry name" value="VITELLOGENIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345">
        <property type="entry name" value="VITELLOGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00216">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48431">
        <property type="entry name" value="Lipovitellin-phosvitin complex, superhelical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="VWFD" evidence="1">
        <location>
            <begin position="661"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="965" mass="110386" checksum="6E77CC64CDA14680" modified="2024-11-27" version="1">MKTDPSLGILQEVAQKTWEETNLEVGSFVTSILDSYANASLPCLQLLSHRIKLVISQIQRFDIGIQHSKDYLWTLFDVCNHYTGMSANDLLDHVLKFLGVREVDIIPKNTESSIFPKTNVVPRNQESWKMTMYNKMFYTVTYNYFDANDVKKTGDTEDFMQHYFRKDGNHNIMGHLVKLFAPSSYHTEAIARTLPYPVEFKRENLLLFSLRFNFKYYKNKASKSLKLLLEPSAYLSTQYTNEMLNLRDCKTVGVYHTNKVAFSDSVELEFAMNNNGKYNFTFRFPVLPKQTFSFHSEAGTYSGAYNSTTLPIMGHKVPIETLPARFKRKNKKFYLGLLSGFQSLNVGTQQDNHSTVSGPYPVTLRRDVKRIYGFPPISTETLSEDLLVGFEETPKDLRESVIRFIEKYQNAGWRRKSINVTRLTLFNEWSTKTTGTLTIAHARHYPKNTSKSTENLEDLIDSFKRPCFIKFMTKDNETYAKERNIIQDAFRGELPSLEDTFKIRYQQSEKGNTNLTVDTFLDFNRTLDGKVYHMVNISFLGLANDPVNIFKYNDKSYDKQIGGAGLDIEFGKEGTSVFTRESLNKTIGTEFETPVMPEVYLPVTHKECIEDVKKGNEYSLACIQAIRERSLLTTSWEISRGQIHVKIFDSYKLKATNNSYPVTCALTDKYVTTFDMVNYRLPLDIPKCTYILSAHCMKRKKFAVMAKFIARSPGTKEIHMYLGKDTVILTPQNKSEVYNIKYNNKQVAVSALKVVTLNLESQIFAYAHDWSGGILVVEGVKAGVKVTYNGKNVFVEVSPKYKGEACGLCGDFNGEPSKEFLGVDGCLYSDSSDFAKILHCQPLRRQHSQQSLHMRKSKNFADFADFGKESTEPEELLNLMTSDTRLRNIVLSREDKMCFSVEPQPVCEDDSEPKETEDIEIDFACYPKNNLSSKHMLVESSYRILTELEGLDPDFAETVPVARSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDR8</accession>
    <name>A0AAV4MDR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_16311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002012">
        <property type="protein sequence ID" value="GIX68969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13768" checksum="61992C020CDDECB1" modified="2024-11-27" version="1">MDWAQVASTSNVGLCPQDQSARHVTTPIRSLLSYTTLGSGHRLPLCLGNSFPAEFLAREWIRAVELPFNCNPVVLTSQVLTWLVTLFVHTYNRVCAMQTTIIKSRNLEHTVEFQPQITQSPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MH35</accession>
    <name>A0AAV4MH35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_146451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002242">
        <property type="protein sequence ID" value="GIX71648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MH35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12314" checksum="3DA6B80D88F036D5" modified="2024-11-27" version="1">MSIASAPSGAGLCIFGQKVVQNVRATHIRGERVVGPKCVGGSMTVKRKRVAFSALSSPAVPLVGPRLAPPDTLTHFLPRANRFVFNGPLCFCYLELVRAGIDGFISPYPFSAPFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNC4</accession>
    <name>A0AAV4MNC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_734871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019941">
        <property type="protein sequence ID" value="GIX73340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18471" checksum="D4778A149288FDEE" modified="2024-11-27" version="1">MQDWKPPSFKRGPFFNIQLSCQLVWELGLGIRGISFEEEANCPHVPVGTTLCGEKSICLACKYARLQAAIIFKRGPFNIQLSASQFGSSVWELGISFEEEANCPHVPVGTTWRGWYILFSDSFASHFSSYGNGAGLEKLGISFEEEANRLHVPVGRTLCGGTFRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRG3</accession>
    <name>A0AAV4MRG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_115411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002544">
        <property type="protein sequence ID" value="GIX74953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10929" checksum="E8D967AD05827E6D" modified="2024-11-27" version="1">MSRREEQKKIVTRKGWTEKYSSSFPLSYTNLLKKMTSSIANRWRKNRLFGDKRTECSALLNFFDADNTYYTPEKKSSRKKRCHLSWLRIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTA0</accession>
    <name>A0AAV4MTA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_591231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020186">
        <property type="protein sequence ID" value="GIX75639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9904" checksum="B3203F76C3C959D9" modified="2024-11-27" version="1">MCVDFDLTSLSSLLNAQCPSRMGRWRNGENLNKGAPEDEMFVHVKGEFMTVNGCLEFSNQSLSRTHQELREGRVLFNNLLISEVLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVV9</accession>
    <name>A0AAV4MVV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_50441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002555">
        <property type="protein sequence ID" value="GIX75059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14544" checksum="287F5809B006BF92" modified="2024-11-27" version="1">MKPTKVVKIKTKQQSVIANLNTKIKGPSPSLIKTHHHCGVSSPPFRQPPEKGSENISSDATTDSEIKKNQNREYKTGGMRLALHFHCLLFGQKILHVLSTPPPPSLYVSEGGKKINKQVFRMLSDWSKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXW0</accession>
    <name>A0AAV4MXW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_650151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020325">
        <property type="protein sequence ID" value="GIX77377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13057" checksum="75A2DC32AA8772E1" modified="2024-11-27" version="1">MVETSTAIYSRTLSHKCATREFCLLRFRPGPVHSSLDDLVTSSSPKNHHIGVALRRTFDRHRIAEDRTLNHKPSNSLDLHRSWITRPRHKSRSNIDIKSSYIKAVAGGVSSVILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZ25</accession>
    <name>A0AAV4MZ25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_795631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002732">
        <property type="protein sequence ID" value="GIX77220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZ25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18843" checksum="CFF14F4FB822834F" modified="2024-11-27" version="1">MRISNQKDEEGWLGKYIKVDSQHKSRPFWTVGTRFARNASDVIWPKIPLRYKKNRVKLQQNSFKRFQGGKDFPSGISQFSVVLRRRRALGPRPVPGLQQAHPSRRGDESDCGGGVRTLLHPAHQRCESSLSLLIALPSSSLDTVDFMKHRFHETLGFHEILWIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2A0</accession>
    <name>A0AAV4N2A0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002807">
        <property type="protein sequence ID" value="GIX77975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2A0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="31835" checksum="100E5CDD3E8CBCA2" modified="2024-11-27" version="1">MESISSNLFSYGSIRNRSHPNTFQLDQSGIDFIQSLLNLINQKLISPTSSILDQPGIDLIQSRFIWNDQETNSSNLFSSGSIRNRFHPNTFQLDQSGIDHPIYSHLSQSGIDLIQLFLSGSIGNQSHLISFTLEQLGIDLIQLFHLDQSVIDLIQSRFIWKHQISSNLFAFGSIRKRFHSISSHLEQSEIDLIQILFNWINKESISSYLFSFETTRKRYHPISLHMDQSGIDLIQSPFMWMNDESIPSNSNLFSSGSIRNDIIPASKYFSSGLMRNPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4R0</accession>
    <name>A0AAV4N4R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_724421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020454">
        <property type="protein sequence ID" value="GIX78993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16670" checksum="A82A392B42CAC63D" modified="2024-11-27" version="1">MPKKKTGKIPTGITVNTKPSYYDNHPSIHHPKIIDALDTRRGFKLDPFYTLTTQTTTSSPKKKTFSCHVTKWIRKGMEVTLHHDTCSQPRHVPSCPSQFATTTTASRRDAIWARHLFFLLRNWAGNVTMADDNERRSDYYCRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAN7</accession>
    <name>A0AAV4NAN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_555241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003058">
        <property type="protein sequence ID" value="GIX80741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10368" checksum="439E2D1FF88814C6" modified="2024-11-27" version="1">MCGGGGLVRPQSRALPWDEEERVALCMSLTMPSNNRALCSSVVGEVASGSGTERIGDAAEEPSDGWRCAGRTASDASTRWFLFFLKRNSYTCWMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NC09</accession>
    <name>A0AAV4NC09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_537831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020752">
        <property type="protein sequence ID" value="GIX82156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NC09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9408" checksum="023FF107C714C933" modified="2024-11-27" version="1">MAVFKLDTVCLSYLGSFLDRKGSKATRENKRRPSLYNNSRKEGWNKKKMAETYSSKESSLRYDGRFIAFDADIFQLNLWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCQ9</accession>
    <name>A0AAV4NCQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_275211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020791">
        <property type="protein sequence ID" value="GIX82582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9753" checksum="ADCAB9E7D059A171" modified="2024-11-27" version="1">MIQAGKYLGKRLLTSGRNIVEDVSQGKSLRDAAKDQFFQSRREITTDILRKLRGGGTRKTIKRKKSILKQQSKRRKAASSDVFSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJ87</accession>
    <name>A0AAV4NJ87_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Shugoshin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_65331_1</name>
        <name evidence="2" type="ORF">CEXT_268681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003381">
        <property type="protein sequence ID" value="GIX83913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJ87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="45429" checksum="D282D40347547096" modified="2024-11-27" version="1">MQSRPMLRSDFKPKPRAERDKEAMPIVRERKLIKFREITNDILNKVKRKVSWDLPAEIQSPLINELRSNENTISERVIAESARSRDSSLTRHDSKEAIPRENSLTRYSPKEPRSRECSLTRYGSPKPESYQEFGSPSASASRRYSDQSIDPMSPRNLMRLKSRSKESDSLEGTDSPNAQTDIDLTCPPKIVPPPRKKSLDQILRRRESADTGSQIVENALSLNASKPPDISENDTCNTENLELAEIETSNTEIKPEQLPRRRRRTSDVSQQNTEDAKTRRRQRTRPDLIDLSHEDAHEIPSPSEAPRPINRMHRKSVKYKMDKCSNRRLSKGFDEDDQTSTLLPAVYRKDSLVNENQEKGSFVPANLVSEDRKELDKPKRMKNRRKSRSLSERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJF1</accession>
    <name>A0AAV4NJF1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">NIF3-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NIF3L1</name>
        <name evidence="5" type="ORF">CEXT_107001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021015">
        <property type="protein sequence ID" value="GIX84916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1390.30:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1 type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017222">
        <property type="entry name" value="DUF34/NIF3_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF13">
        <property type="entry name" value="NIF3-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037490">
        <property type="entry name" value="UCP037490_NIF3_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR037490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602678-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX84916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="342" mass="37758" checksum="D13824B607E4FE66" modified="2024-11-27" version="1">MDLCSVVKSFDKIVPKQLAEKWDNTGLLVEPLQKCPISTVFFTNDLTEDVLEEALSLKANLIVSYHPPLFTAFKSLSCKNWKDRIIMKCIANNIAIYSPHTACDAVEGGVNDWLLKCFDITCILPIKPVHEVNSHVIECFVKEDVNFNTILGANIDFTILMRSSFEDNLCYKILINSAAPTTVCQMLLSNPSFLTVTSKECALPNASKLTGMGRIGTTNEPLKLNECIQLVKNHLKLKNLRFALGVNCTLDTEISTVAVCAGSGASLLKGVPADLYITGEMSHHDLLDAIHKKTSVILCEHSNSERGYLVNLASELQHKLHSVHPDCKFIVSKIDKDPVSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMV4</accession>
    <name>A0AAV4NMV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_270760_1</name>
        <name evidence="2" type="ORF">CEXT_577171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003542">
        <property type="protein sequence ID" value="GIX85778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13030" checksum="48C34529FFDCC6BE" modified="2024-11-27" version="1" fragment="single">LTTCVMGSVIPMNVSYTQASCIVGNCAVNMNPKPPAKPKREADEEPDQENEQRETIASSLFGGDMSSLSNVFEEEFQVQSLPYTMVVDGHNVTITKVEEYFVHSEEQPDEDLLDELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NP03</accession>
    <name>A0AAV4NP03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_587881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003603">
        <property type="protein sequence ID" value="GIX86620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NP03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9241" checksum="DC96D73C21915042" modified="2024-11-27" version="1">MFIIKEDLYDIIKDESPVSLDADRQKDNLQNDMATMQKSLTAMNLKTEEKFCNEKKKKEMDGSHKRRNEEYRRKLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQR1</accession>
    <name>A0AAV4NQR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Syntaxin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">STX7</name>
        <name evidence="3" type="ORF">CEXT_206671</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021070">
        <property type="protein sequence ID" value="GIX85512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Syntaxin N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX85512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11084" checksum="8D611AFA6EB30F31" modified="2024-11-27" version="1" fragment="single">MANSYSNGYQYSTYSTDTSGGYGEFTRLSEVISTNVQKVSQNVASMQKMVNQLGTPQDCESLRAQLHQVQHYTNQLVKDTNNHLKELSLLPNPPNLSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRG3</accession>
    <name>A0AAV4NRG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_788611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021235">
        <property type="protein sequence ID" value="GIX87427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="22903" checksum="F76E82C989095558" modified="2024-11-27" version="1">MSEEQSYDGQWTTPPDSPLISQGSIQQGGMFNCWPPPVPSQNVTVNPTGTVLQPIPLRISAASSTGLADMNYRPSTPYLRGVEAFRGASAICEREQYVSAFSNVGDQTSGFYAERAVLNWNPLELNAGRTDLIRRYDIPDYAYSGRPTRRARVPTLPHFSDFAPRRRYLLENPYTVRYSPYELPGHQVWREDAARLCPSVDPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRK3</accession>
    <name>A0AAV4NRK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_404841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003679">
        <property type="protein sequence ID" value="GIX87406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10320" checksum="86EA4617BC97414B" modified="2024-11-27" version="1">MINLAEIITKTNLLLLKNVTFIISSSLPSSLNFETITQPAKALVNSGDLQPPSHPSEEAEWTQKGNYSGSPSPIQFPRELPRLLNEKTFPNLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVE9</accession>
    <name>A0AAV4NVE9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_28831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003706">
        <property type="protein sequence ID" value="GIX87725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="9013" checksum="A0B8FF4F8C6AE908" modified="2024-11-27" version="1">MEGDQRDRRYYPPTRHNNLDELCRSTQFTRKEIQHMYRSFKEGFQNLTVTVGIVERAGFNSQEDIQVVSAALRTLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWI5</accession>
    <name>A0AAV4NWI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_404911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003679">
        <property type="protein sequence ID" value="GIX87417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10206" checksum="5F0B6B813873DE1D" modified="2024-11-27" version="1">MENYALVCRRFPGARHLNNNARTVKANFKIVCTSACEGRSAKRVSVTADICRDAVIHWALLPGTRLPAFSRGWLNFDYPTTPTTQRLPKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWW6</accession>
    <name>A0AAV4NWW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_280461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003745">
        <property type="protein sequence ID" value="GIX88235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="22145" checksum="07E76AB32FF9EB6D" modified="2024-11-27" version="1">MYPLEIPCHLFQIPADVEFRSPNIRETERFDAVMVGSSGNAEGQIKFHIFNTVNGVSCRPLLPTPNTTVCKFERRKKKSSYRLLTLTRHFHRFINQDFPLPRSPKCVFAASGRLSARVVGAPHYHSICRSVRRRPLAAVRAKVDQVSAGQSPACGRRTRSLRTRRRRPSSHLRMGFPFRYSRANKCVHVIRCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P061</accession>
    <name>A0AAV4P061_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_569051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003941">
        <property type="protein sequence ID" value="GIX90444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P061"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="36" mass="3890" checksum="0F491A0871B43659" modified="2024-11-27" version="1" fragment="single">MQPEDQLASGRPKKATLTFSTTGLYSSANTGLYNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PC00</accession>
    <name>A0AAV4PC00_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uracil-DNA glycosylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TDG</name>
        <name evidence="6" type="ORF">CEXT_187111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004342">
        <property type="protein sequence ID" value="GIX94144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PC00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008263">
        <property type="term" value="F:pyrimidine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10028">
        <property type="entry name" value="UDG-F2_TDG_MUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015637">
        <property type="entry name" value="MUG/TDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159">
        <property type="entry name" value="G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12159:SF9">
        <property type="entry name" value="G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="5">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX94144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="334" mass="37985" checksum="521B57AD14DD3B8B" modified="2024-11-27" version="1">MAHGIGFTNIVPRPTKGSADLSRKEIREGAEILLSKLRKYQPKIAVFNGKMIYEVFSGKKNFDFGRQPDPIQGTGISVFVMPSSSARCAQLPRAVDKVPFYIALKKLRDHLCGTLPDLDFSEVSFPDVKLKVEIKEDNHEECYTDYRRNDVSATVHRSLETETELRMMIPVRGKRGRKRKTDLGRYPVPVVHTDGVPVRPRGRGSGRRGRGRRPVEHSGYSPSGSSWSGSSTVTSPYYTAETTTPQHAWQHWQESQNGIDSFPDQSQTHNMSPVHSYQMPHIDHVVKQPQNDQYYEVYSRSYMGYSQADCSYVPQADTYAKVKDECYDTNFSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PE25</accession>
    <name>A0AAV4PE25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_150901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004532">
        <property type="protein sequence ID" value="GIX95557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PE25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8393" checksum="C5EAFBE000DFA757" modified="2024-11-27" version="1">MKEEQFGVIRFLAAEGVGVYERMMNLGASPTNRNQMKKTKMETSQLHTNTGGVLRCFILMKKVNKPGRLHPAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHN2</accession>
    <name>A0AAV4QHN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_215851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006124">
        <property type="protein sequence ID" value="GIY07565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11813" checksum="DF245027032316A6" modified="2024-11-27" version="1">MILKKTDLLFKRESELKSKQAIIEDLVAEKNKKTKVIRDEKLWACQKELKNFKSQIKCLLCEKLMYESNSSKYEREIKNLKEELRKSKLSKCPKCQQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QM98</accession>
    <name>A0AAV4QM98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_197597_1</name>
        <name evidence="1" type="ORF">CEXT_451241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006339">
        <property type="protein sequence ID" value="GIY09185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QM98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="516" mass="60700" checksum="88A98A2CB011900B" modified="2024-11-27" version="1">MQVFHIYRLPLILICLQHCRTFKAVKITFKKMPPISLYETCLDRIIELIKVEHWREEKDNPFSRLPSKIVELLVEVCGTSQKIRKFSYFRMLLSSGKLRQLKICFPVIFIDTCMVLPQMLTEKGCMNITVLELDRNFKNYRSEWLEKLLQKLPLLESLSVQTLFNPLALKDCKRLKSVKVIRIFNYDNFLSEAVDTLSHMEDLEEFDILLYTTESSIFLNVVKMLKNHKKLTSLRFTDSSRAAHHIMTNNTGDELPKYGLRKCSWTYDTSSFEKRNKIYISFLERVSSSVLLFPLVEELEILVLSEDCFEYLKELKHLRSLKLNFNRHSTYQSDFSFLSGIGQQLRHLCIISFKEIPVNAISRYCFNLEYLECSATICDSIKSSYSFRMLKRLEISLTNANSLLYVFQNVRNLKELQFHNAAVFDDLRLQEILNRDSLAFNHLDKVFVRDCMLSREGIRIFLEHAVNLTTVYIKSSHFNEGAGIDFSDVIKELQRDVVHDYFAVEHYFNNTSYFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMV6</accession>
    <name>A0AAV4QMV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_506511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006640">
        <property type="protein sequence ID" value="GIY11378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="21243" checksum="FAD0F874CD6F12BC" modified="2024-11-27" version="1">MESWKGFVEDCAPKVDLCFAPAGSAVIYEKIAGRDWPQDGWLTAEFRGRCVPGITEINFTLSINSGRYSSRQDCDFVAENKHSLLLLLNSWGNIITLHNGSGAVRSYLGRHYCVRCRNRRRTLLLLKGWRRVILMGHRCQIPHLLPPDWMIFIGQNSLVMSEVKECKKEDVQWTLRKGICCYFSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPC9</accession>
    <name>A0AAV4QPC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_327861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006443">
        <property type="protein sequence ID" value="GIY09905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10736" checksum="FECC17568065D828" modified="2024-11-27" version="1">MEKVGAIILISHPLNDAPFCASFLGSRDEGCVNHSYPCKAMRGSLINAAPSEIYGQKKRVEGSFRRQVGGFYDHVSKLGKCIRGDGLLEEESSNCKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSF6</accession>
    <name>A0AAV4QSF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_454451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006689">
        <property type="protein sequence ID" value="GIY11759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12636" checksum="DBC14882B76FC060" modified="2024-11-27" version="1">MKVIVRGGQLLLFLLHRDTADSILKWTRQLTRLFSLWMNRGLVMWKKPGIYYHPKNIRETDLYRGVSMGGNFIPHDAKSQKACFRDDFLQQQTIQNMEWPALSLEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTS5</accession>
    <name>A0AAV4QTS5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vitellogenin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_494352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006825">
        <property type="protein sequence ID" value="GIY12664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="15812" checksum="BCF51F1C14F97D5E" modified="2024-11-27" version="1">MLNKPSAHAWKSASVLMERRKIAHVALFALAAETRHAKSNVDPSRKVIVAAAKKLKKLHVPVETAVSVVKAQPVIKVHPAFAQAIADAAMIIPAKYMSNALVGMGVNAVVIKPVNPLPNASVEIAANVARAKHAIYLPAVSAATIVNAVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R370</accession>
    <name>A0AAV4R370_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein CG3556</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CG3556_2</name>
        <name evidence="3" type="ORF">CEXT_497451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007304">
        <property type="protein sequence ID" value="GIY15922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R370"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831356" evidence="2">
        <location>
            <begin position="21"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY15922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="247" mass="27391" checksum="24989C2682C37432" modified="2024-11-27" version="1">MKFFTIAFLVFGYHLSMVLCNNCQIEKSLSGTISHAEITFSNKRSKVCDGVKDCSNGADEVGCETGILAVRGIAEARQNAISWLKKKRSASWGWRDYTSRAVVALYLASGSNFNGTILEEELMAKQTELKTAVALLRPSLTNSDLSMFINSLLVTCHNPRRFYGHNLVTRLKEQVKESKGSTHPFFILGSLQCSGVLASESGFDLNNILNSSSNYPFIEELQAVAIIALSCNFNNMKKLTNYFCQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R396</accession>
    <name>A0AAV4R396_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_495851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007311">
        <property type="protein sequence ID" value="GIY15952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R396"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9150" checksum="DE56686CFA7668EE" modified="2024-11-27" version="1">MPNHPQDQCRKNSSRTLRETLFFLIITSSRLQGHFSLRPAPLSAPTNLRAPTAFRERPPAITLQSFIEMLDFRERKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5L6</accession>
    <name>A0AAV4R5L6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_256651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007262">
        <property type="protein sequence ID" value="GIY15662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5L6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7734" checksum="39F7B84836B4F2E3" modified="2024-11-27" version="1">MRGTIKPNAFPRAFESSISGRIEVLKPIKEGKKPAVFVEGGQSLLSCFAIQEVSTLHSEFNGLRHAKGTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6X1</accession>
    <name>A0AAV4R6X1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_479181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007287">
        <property type="protein sequence ID" value="GIY15828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6X1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13667" checksum="24D8C02269A5E346" modified="2024-11-27" version="1">MLRGSPKHKFSFTALQYGNMQNSNRIPQETYVPDSMHIQMGKGIIQGNNFEQRIEMFTCYNPNASSPTLAISRQQLSVVSAPGLVEFSALDKLRFNGIEMFAGVIKSRYLRFALKRKYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R836</accession>
    <name>A0AAV4R836_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_414711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007629">
        <property type="protein sequence ID" value="GIY18473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R836"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9562" checksum="848BE14F32346092" modified="2024-11-27" version="1">MISNRTNFDAHVQTDCGAVDACLESVLDKFFQQLVHCPQLFYTLSACLQAHHSYSVACSSYVYRTNKKILTFRVNAFVRTPPSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJJ4</accession>
    <name>A0AAV4RJJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_238111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007949">
        <property type="protein sequence ID" value="GIY20931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19322" checksum="B6028BFE97203532" modified="2024-11-27" version="1">MTFFVKSCSDVLTLGSTHQCSDSGKYDVHRNDSCHPYMYHYQFIDERRMENNTFPEVYPEFKQPCISCLSNQINLAYEGKLGITKLRNAFPENKWCVSNRRSPLQLKNGAKECRFVILPSLLSPPPLFPTPLFFAAGAVKTIFREKEGLRFSEFRFVCSEEETNAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMB3</accession>
    <name>A0AAV4RMB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_456861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008043">
        <property type="protein sequence ID" value="GIY21647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9381" checksum="5C296EFB1EC284F3" modified="2024-11-27" version="1">MAAEWREIFDRTSPGISSSDNNPPTLNPNCRALGCARHPYFRTRGNDLGRASVIHAAFARLRLPITMVQVAVAWFKHTFVFHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRH5</accession>
    <name>A0AAV4RRH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Signal peptide peptidase-like 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SPPL3</name>
        <name evidence="8" type="ORF">CEXT_16421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008222">
        <property type="protein sequence ID" value="GIY22946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030660">
        <property type="term" value="C:Golgi-associated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF22">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY22946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="21086" checksum="DBB33B51F025BE34" modified="2024-11-27" version="1">MDAMGMGLCVAFIAFVRLPSLKVSTLLLTGFFSSYIFNANVMVKVATRPAENPVGIVAKKLHLGGVVREAPKLSLPGKLVFPSMHNNGHFSMLGLGDIVMPGLLLCFVLRYDAYKKAQICSAETGVPPPNQLNKISYFHCSLIGYFLGLLTATVSSEIFKAAQPALLYLVPFTLLPLLTMAYLKVISEECGVNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTE9</accession>
    <name>A0AAV4RTE9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Neurensin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_48489_1</name>
        <name evidence="2" type="ORF">CEXT_284851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008351">
        <property type="protein sequence ID" value="GIY24096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024883">
        <property type="entry name" value="Neurensin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14796:SF3">
        <property type="entry name" value="NEURENSIN 1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14796">
        <property type="entry name" value="NEURENSIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14927">
        <property type="entry name" value="Neurensin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31541" checksum="854CA424779AFF87" modified="2024-11-27" version="1">MNRGGTDHIAEEQTNVPVAKDEKVKILPKALSKKEKSDHQKLKFKFKETACLLNSEHIKHEFKLSDKSNNNDQVAIPMEGIADDIEKEEAPPKFFGVKNYLHTFYESYNFKNPQMYEDIPEDSEQPPKENKSLKFYWKLSMSITLAVVVIGLILILIGFIATLHTSVADKKSEEFLIIDKSDTTLNDYLRACRLTGVGMFVSGFVSFLIAILVALYWNYVHGGTASDDEESDSLCLSYNPDNYQQGTDQSVPIPENVVTAQIKREEDDVVATGPGIVSPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXV5</accession>
    <name>A0AAV4RXV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Acidic phospholipase A2 PA4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PA2A2</name>
        <name evidence="12" type="ORF">CEXT_561661</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the phospholipase A2 family. Group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008606">
        <property type="protein sequence ID" value="GIY25934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050482">
        <property type="term" value="P:arachidonate secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.90.10">
        <property type="entry name" value="Phospholipase A2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016090">
        <property type="entry name" value="PLA2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033113">
        <property type="entry name" value="PLA2_histidine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036444">
        <property type="entry name" value="PLipase_A2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12253">
        <property type="entry name" value="RH14732P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05826">
        <property type="entry name" value="Phospholip_A2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48619">
        <property type="entry name" value="Phospholipase A2, PLA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00118">
        <property type="entry name" value="PA2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Phospholipase A2-like central" evidence="11">
        <location>
            <begin position="9"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY25934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15667" checksum="258205B589059566" modified="2024-11-27" version="1">MNEWYQVGGVGDIAESFEQLGTQVEVDACCRAHDHCPVKLKAFRTGYGLINLSLYTKSHCDCDREFFSCLKTSRNKVADVVGNFYFNIMKIQCLKEHRPFVCIENRTETDGMTTCIKWGEDPESKKMHTTVTHLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0Z1</accession>
    <name>A0AAV4S0Z1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_698121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008645">
        <property type="protein sequence ID" value="GIY26210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0Z1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15005" checksum="42E3DAC67A30AEFD" modified="2024-11-27" version="1">MHFCVEFGGPLFRFNLYSSCASGIWISRLMGCHNLHDFNQRTAKSLANWQDRFDRQVVSVSLETFKSDTTPNMASRTPSNSLLNFWQQAPAAVTDSVSQPVASRPLKASLPIRGLHTARSITTEMLPLFSDQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S129</accession>
    <name>A0AAV4S129_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_16741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008921">
        <property type="protein sequence ID" value="GIY28238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S129"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9975" checksum="297C7419C83F934B" modified="2024-11-27" version="1">MVESGFPTESGNYIPPGTNHELLLYLYLRSCTSFESAKVACHVRELPFGNNYFVQQIKSERHFLTITSCRRLCGADGRKRDGWDPYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S5W1</accession>
    <name>A0AAV4S5W1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_457541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008884">
        <property type="protein sequence ID" value="GIY27956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S5W1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13594" checksum="10945E5C36828C76" modified="2024-11-27" version="1">MAKYLIMLQWARPWLTGMYKKKKILTTTMDIGVIGKVIPTPQKFGFLVFKNAKGNRTLLGADVLRAAGIVLNLQKGQWYFSGTPHQQFNFIATPPDIKSLLVMPPASHPYQRHRNEGARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STK6</accession>
    <name>A0AAV4STK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010123">
        <property type="protein sequence ID" value="GIY37105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12790" checksum="4670B9690DFDAB4E" modified="2024-11-27" version="1">MKTSRTPTTPEDNPEICNFSCLARNLGVGCANPAGGFLFSKINEDCWKILPPCPTKLARGCVEMESKQLVVYREGAADDLCGSIKAPRCRPELLLLEEKSRSGVKLVNLKVTAAVGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THT2</accession>
    <name>A0AAV4THT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011130">
        <property type="protein sequence ID" value="GIY44352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9478" checksum="C5C35B4F1E8ADD71" modified="2024-11-27" version="1">MTGPSLTEENKALHVAGRKPIRRRGIALRNQCMTDALLVIRLISDVSKKSSLDSELKHTAFATIHECFPDDSWLHVYGDGSAAESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYL0</accession>
    <name>A0AAV4TYL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_360981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012019">
        <property type="protein sequence ID" value="GIY50741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="262" mass="27978" checksum="6730CFF49942CA18" modified="2024-11-27" version="1">MKSLPSECIRVENDTVTVKHTFEEVTYTIPDLTTENGLARRRGVCGDLQGNRRRRHFRYSEPGEPLSVGAHAGYPPEGAGHRHRRLPPPGGVPAAVPVAQGGRQVRVPVHHPAAQDLQPHGDHPDQAARVRPETLLSRISEQVPAPGVRLRRGGGADQGELPAAAHQDQDGRVEDGRLQAELRPSGTSSFITPKPIGPPGPFFVVTLYNFGLIAGAPRIFQVSVLSTVDGVPQVPHGGVPLAAVRDAREEDHQDTGHGPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZW5</accession>
    <name>A0AAV4TZW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_425551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012062">
        <property type="protein sequence ID" value="GIY51056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043697090" evidence="3">
        <location>
            <begin position="23"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="585"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY51056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="706" mass="72679" checksum="C4A7A4E6B67179AE" modified="2024-11-27" version="1">MGTTILFAAICGLICSGQLVSGQAVAMASSNSGNNGWSNANSNSNSNGNNNGYSSMSNSYGSSSYSDYNNGGNYQSNGDSGNYNYNYGNSYADSNSNAYSNSYGNSYGNGNQGYGPYYYNYDDYGSWAQSGGSGGQGGSSSASSSSSSSSSSYLGGGYDYYGNGGYNYQNGGGSGGGGSGGGGGMEEEVMEEEVMEEEEEEMEEAEMVEEEEEMEEEEMVEEEEETEEEEMVEEEEEMEEEEEEEMEEEEGGNGGAGNGGGGGGGSNQGGGGGGRGGGAESGSESGATSGSGGGRGGGGNGGRNGGGNGGGGGGNGGGGRRWRRRREGGNGGRNGGGGGGGGAESRSESGATSGSGGKRWQPRRRRRTWRRRRGQPRRRRRKWRRRRRKRRRSRRRRKRRREEKWRRRKRKWWRKRGGGNGGGGGNGGGGGNGGGGGGNGSNQGNGRSRILSLMERLASMKRGGNGGGGNGGNDGGSNGGGNGGGKGGKGTTSATSTTSSATSSATTSSGRRGGNNGGGGRTTAATASTTNGGRGGGNNQRGGNNQGGGNNQGGGNNQGGGNSSQAFASSRSGSNGGRGNGQNNGGPNNRNFFNNGRPRPNNGGPGPNNGGPGQIMEDQDQIMVDQDQIMEDQDRIEADQDQIEVDQDQIMATMVEIIMETIVHLLAVAVAVAIVLQIMGDHHHHHHHHRHQVAVSIIFIYVLFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3E3</accession>
    <name>A0AAV4U3E3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_769601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012217">
        <property type="protein sequence ID" value="GIY52258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18792" checksum="A84F02EDB1233916" modified="2024-11-27" version="1">MTKLNTIGRTAASFLKKWDLLLKMMEFEVIRESAKIWEGRRVECPKVLVTPSEVGGVLQIHLDIFGQIFVLGKVTHFDDDETVHVVLESYVGKFELKHAPLSLQKAPAKKIGIKKLENSRNIHSLKENSERTFSILKNVIQSNCMNLHACELHAFELLNCMHYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7G3</accession>
    <name>A0AAV4U7G3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tyrosine-protein phosphatase non-receptor type 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PTPN4_1</name>
        <name evidence="2" type="ORF">CEXT_405591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012394">
        <property type="protein sequence ID" value="GIY53711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7G3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45706">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45706:SF4">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15766" checksum="FB6D4BF3F4830156" modified="2024-11-27" version="1" fragment="single">RERKKIDFIAYNSATKLQNKLEDQVAQTTHSNQTFLTENSNGYQNALEPPDLIESKDQSLDQSSFLIDTSTDIQSSQLLQESMLTLQLSLEDRATFEDLFRRNPHESMNVARLPENAPKNRYKDVLPYDSSCYFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U889</accession>
    <name>A0AAV4U889_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Metazoan SpoT homolog 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Penta-phosphate guanosine-3'-pyrophosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hddc3</name>
        <name evidence="6" type="ORF">CEXT_483081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">ppGpp hydrolyzing enzyme involved in starvation response.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MESH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012429">
        <property type="protein sequence ID" value="GIY53915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U889"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008893">
        <property type="term" value="F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052194">
        <property type="entry name" value="MESH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46246">
        <property type="entry name" value="GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46246:SF1">
        <property type="entry name" value="GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13328">
        <property type="entry name" value="HD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00040793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY53915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14398" checksum="28D3E57048CE1094" modified="2024-11-27" version="1" fragment="single">AALLHDTVEDTDTTFEEIEKVFSPTVRSIVEEVTDDKTLPSATRKQLQIEHASKISQEAKLVKLADKLYNLRDLLRSTPKGWNEERVQNYFVWASKVVSQLRGTNKALEKELRLIFIGRGIQWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9G5</accession>
    <name>A0AAV4U9G5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoenolpyruvate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ppsA_4</name>
        <name evidence="1" type="ORF">CEXT_666891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012514">
        <property type="protein sequence ID" value="GIY54411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9G5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051549">
        <property type="entry name" value="PEP_Utilizing_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615:SF1">
        <property type="entry name" value="PPDK_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="229" mass="27082" checksum="D381A8B144978BCB" modified="2024-11-27" version="1">MALWSNHWCRPQGDCGWQHAFIEYCLHSRNEAEEWLQTTTCLSGYKFRQFLKRHGHRCLKEFDVRSITWEMDAKILIKLLQSLAGVGKEELKKQDDDLSKIFSQLHVSLSFVHKCLLRFVLPNCRRAVRARAAGKSLTIKSFHHWRKGYRHLAKLMVSEGRLPDEDLIFFLTIDEIEELLETRSPSIISRANYRKKMYPILDDYKFPEIIKGNQNQLMMKKNRRTPTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9U6</accession>
    <name>A0AAV4U9U6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit F</fullName>
            <shortName evidence="4">eIF3f</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EIF3F</name>
        <name evidence="6" type="ORF">CEXT_49691</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012536">
        <property type="protein sequence ID" value="GIY54642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08064">
        <property type="entry name" value="MPN_eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03005">
        <property type="entry name" value="eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027531">
        <property type="entry name" value="eIF3f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF6">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="11"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY54642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="300" mass="33795" checksum="49C90AB48F500ABD" modified="2024-11-27" version="1">MNSGVSPHLTVKIHSVVLFSIIDSYERRNDSQHRVIGTLLGIHEKGAVEVTNCLCIPHNESEDEVAVDMEFAKNMYELHKKVNPSEVIVGWYATGADVTGHSVLIHDYYSREANNPIHLTVDTSLSDGNLTWKAFTRERNGRIYHDLILKNLRGRTLSLLYIFFGVPGKNTGTMFTPCKVEVIGYIPEAVGLKICQQTKHNKQRSVEVMPDLELINHAIHEMLQQSDIVIDYIDDVLANRKPADNTVGRMLMDILQSIPKMSSDEVQDMVNSNKKDLLMIEYLAMLTSSLVALKQSISFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB99</accession>
    <name>A0AAV4UB99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_352381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012591">
        <property type="protein sequence ID" value="GIY55006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10381" checksum="CD0581F710E5A236" modified="2024-11-27" version="1">MPLSPHCFPRKFITFTRRIIPTKWGTSRTPSTLPWVSFVFPLFLSKVGIFLPPKRDLTVQGLYAPFAREWPLIWAEEPSYTNSVCLQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDY5</accession>
    <name>A0AAV4UDY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_660651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012701">
        <property type="protein sequence ID" value="GIY55940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7380" checksum="65B87AE3D75A30D2" modified="2024-11-27" version="1" fragment="single">MSVSIVFAAGCSLMRGSSWKRFITFSPNSLYSQPDTTITFTHVFDCADVIPCVWISWKEFAIVVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDZ2</accession>
    <name>A0AAV4UDZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TPTE2</name>
        <name evidence="8" type="ORF">CEXT_730321</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PTEN phosphatase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012712">
        <property type="protein sequence ID" value="GIY56006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14510">
        <property type="entry name" value="PTP_VSP_TPTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1110:FF:000004">
        <property type="entry name" value="Voltage-sensor containing phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045102">
        <property type="entry name" value="PTP_VSP_TPTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF60">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10409">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22785">
        <property type="entry name" value="Tc-R-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="73"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="C2 tensin-type" evidence="7">
        <location>
            <begin position="171"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY56006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="317" mass="36705" checksum="7DE5D6079A9A2652" modified="2024-11-27" version="1">MVSQNKRRYQKDGFDLDLTYVTERVIAMSFPSRGKMSLYRNPIKAIARFLDFKHKDHYKVYNLCNDHNVPSINDMIRFVKNVREWFDQDKSNTIAVHCKGGKGRTGTMICVWLVEAGLFGSAEASLDYFGNRRTDLTKSNKFQGVETPSQNRYVGYFQEVKEKYNGVPPEEIPLRLRLIKITAIAGIGRGDGSDFTCEVFIGRSKVFDCDFGINKNCQAEYKSEADVLEVMVLNCPILHGDVKLKFQCSSRGVPKGYENCPFYFWFHTSFIENNRFHVQRDYLDNPHKPKTWKVFREKLSIELLFSPPDDKLDIPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UH28</accession>
    <name>A0AAV4UH28_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">unc-89</name>
        <name evidence="8" type="ORF">CEXT_89351</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012862">
        <property type="protein sequence ID" value="GIY57130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UH28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000097">
        <property type="entry name" value="Bent, isoform F"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000425">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="10"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="120"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="221"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="333"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="437"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="542"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="630"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="767"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="867"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="958"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1196"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="993"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1206"/>
            <end position="1231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY57130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1265" mass="142323" checksum="F12F273C76C939A8" modified="2024-11-27" version="1">MGVADEEVAPTFTKKPTLREEDDGNKLVFECQLVTNPKAAIQWYRGDVALNDDQRTKVTSKEIGPHKYNITLELNDVFETDAGMYKVMAKNKYGEVSASINLNFSPADQPHDYQTDGIPPTFAKKPSIRQEDEGRRLLFECRILADPKPSVYWFHDNDAVKESSRCKVKLDKDGNAYFSTLRIDDVTIEDAGKYKVTAKNELGESHATISLNFDSEDEGIPAEGTRPLFTEKPIIKGADNFKKVTFECRLVADPKPTIQWHHNGKPISDGGRYKYGLISDKHNHVVSLEVQSVVAEDGGEYKAVATNKHGDGHANITLNFENDKPQIPKGKTPRFPKKPTILQEGDNLILQCILEADPMPEIVWYHGTKKITDGKRHKIKQKSQGAEMYLLTLEIQDPVTEDGGNYRCNAINDLGESNANIALNFQGGDNKSEGLAPEFLEKPRIIPKEGGKLIIMQCKVKAQPAPKITWYQGTKLVKETNRVQAKVMEGAGDEFTVSLEVRDPSKDDGGAYKCHMINEHGELNANLNLDIQAEKPPAGEAPTFVEKPKITPEDGGNRIIMECKVRASPKPDIKWFCDGVEVHESTRIKQTIKQDKDNLEFTDAGLYKCNVKNVHGESNANLTLNIELAPVIKEKPKIIRKEIHKKVVIECRVASVSKPKCTWFKESSIVSESSKHTVRITEITKGEFAVALEIDKPSGDDKGNYKMVAKNEKGEITSTAVQVDIEEEKKEPEKKILAISVDFISNVIIMGQKTSGYFFEKPTGEKPKIVQDLKSITVESGKSAEFICKIESKSKTTVTWYKGTQVIKESKDFKMSFDSTTASLTITQTTTTSSGSYKVEFSNDFGKAESSAQLTVEEKKKVEEKKEEKKEEKKVEKKEEKKVEKKEEKKVEKKEELKVEKKEELKVEKKEEKKTEKKELKVEKKESLKIEKKEELKVEKKEEKTVKKESLKVEKIEEKKTATKQAAVPQISVEETPAPKGKGPQVPVVIKEPSPEPGRKASTDVSAIPGFGSRRGSYVDIPSPGGSRRGSIIIADEKGIVVDETGKTKKLRPGEMLEVAAPKRRKSIDTRRVSISELQELIDKPCTPLRAIPDNDKCAPAILDFQQNYSAVEGATAYLSFQVEGNPAPQFHFYKGISEIFEGENQKLKMKESTKLLLLMKLEKTHKKSVFFVSDESGMDFRAMLKKRQYAKWKEDQDNPDWNLKPPEKERRPSLRETKNGERRGSRESRRPSLAELIPDWPILQKVVKDSEVGGWLKMNSIFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPT2</accession>
    <name>A0AAV4UPT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_628071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013251">
        <property type="protein sequence ID" value="GIY59875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8848" checksum="E12F4D2D20EBF9FD" modified="2024-11-27" version="1">MILDFTKLFDGSQSNACLLLNIAKKASTGPIFKPIPRKLHRRAVYGGCSIGIQVQASNVEKKFCTSEMHKTQIPHCEIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UU07</accession>
    <name>A0AAV4UU07_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cuticle protein 10.9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_26024_1</name>
        <name evidence="4" type="ORF">CEXT_446261</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013388">
        <property type="protein sequence ID" value="GIY60870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UU07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY60870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="14597" checksum="485BA7CDF23B965F" modified="2024-11-27" version="1" fragment="single">PGQLRHGLQREQLTGGASFYREKGYTNGTRTGSYGYTTRNGLIRIVTYVADEAGYRAELLTNEPGVSAVDPASVTVTKEQEPDPVALALGPTGVPLQTSPTTGSSVVYVGQGDPVKNYVVGAAQVSVAFPLAQYQYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCJ5</accession>
    <name>A0AAV4VCJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_660081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014332">
        <property type="protein sequence ID" value="GIY68136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8934" checksum="9F19D11E9FCD4204" modified="2024-11-27" version="1">MQGLRKYFPQHSNSLWALRCGGAVTACIHKVNLWEMTAALVSLRECLFCFNMLSLIYVPLLPRGKEKRNCYVTEKFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNB2</accession>
    <name>A0AAV4VNB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_346431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014753">
        <property type="protein sequence ID" value="GIY71089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18411" checksum="6C1547E532B810AE" modified="2024-11-27" version="1">MERDATMDYSDRGSTPGASNPELTAQKLYDAYAAALTRHSPDDDDLKEIKILHDDFQHAMREVSKLELCPLPFVKNIKLTTLTVKLSAMLSILTIPEHDNDGFTMPSKKFIAKINYAKYPQQLVETKNSFHKLNVNEQEEHDSDTIPVVKKCHPLRSSQLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRG5</accession>
    <name>A0AAV4VRG5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Gyc76C</name>
        <name evidence="9" type="ORF">CEXT_174541</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>GTP = 3',5'-cyclic GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13665"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57746"/>
            <dbReference type="EC" id="4.6.1.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01014911">
        <property type="protein sequence ID" value="GIY72184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF474">
        <property type="entry name" value="RECEPTOR-TYPE GUANYLATE CYCLASE GYC76C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="41"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY72184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="25243" checksum="697EF4F5EA6A2B83" modified="2024-11-27" version="1" fragment="single">SYAGDYIRVLLFLTISLSVLCWIMYKKWKYEQEIAGLLWKIPLQDIQRYGSHGIVSSESRNSVNSNNSMESKTSQGKKKKEMKIMRELHHDNINPFIGACVQPHYILLVTEYCAKGSLKDILENSDLKLDHIFISSLIFDLIKGMIFLHDSDLKVHGNLKSSNCVVTSRWVLRLTDFGLGDLTTAAENEIFLNYEHYRTVNVGDISFQYASRVYTEVIGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRH2</accession>
    <name>A0AAV4VRH2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_107331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015017">
        <property type="protein sequence ID" value="GIY72985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8808" checksum="5066C699FD0260EB" modified="2024-11-27" version="1">MQSRRVYGGIAVLPAFTPWHHTVKAQQPDPPVQNLMRAHFKGPGRKANCSCVKRRSVTPLGWGGHSPNHIRNFISHSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRK3</accession>
    <name>A0AAV4VRK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_307601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014963">
        <property type="protein sequence ID" value="GIY72564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13992" checksum="73EB87FFA097D794" modified="2024-11-27" version="1">MEKNSKTFLCILPPHHPWRLASVAVRYYRKTISRGRHHKTSESTISVSGSEEGTCVRFCGGGDFFFQTRLVLCAQKTMFDKVLPSGSRGRKGKKCFREGFWNRLRDVRWAKSFLDLIFVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTG2</accession>
    <name>A0AAV4VTG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_698441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015050">
        <property type="protein sequence ID" value="GIY73239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="20826" checksum="22A01A0314A15259" modified="2024-11-27" version="1">MRGDEYNMHPQDSPTRGRSPTTSGPTSQTGSPDLLLGGAETTAPNTTLRALTEDPAAQAPSKRPPLATIITAWASTHNRSTALAAQARPSAHSLPLRGVRGSPAAPHAEPALPPALRRALRGENQLPSQVHSPMPQHRGVLSVMNFPRLNPSPTHMPKLQMPPLWRDRTSTYLETQCPPLVGPSGKVAACQVTSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVX3</accession>
    <name>A0AAV4VVX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_190761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015177">
        <property type="protein sequence ID" value="GIY74158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10331" checksum="A0475ACD943C1583" modified="2024-11-27" version="1">MVWQQHLIVLHVKNQCPNLKCLYLPLFCLYLQNRILILAGIDIAELIKAIDQSKYVQRPTDSITEFPPNHDVTEHVTLWVDGFVNTAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VYY7</accession>
    <name>A0AAV4VYY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167330_1</name>
        <name evidence="1" type="ORF">CEXT_318541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015352">
        <property type="protein sequence ID" value="GIY75506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VYY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20908">
        <property type="entry name" value="LD15586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20908:SF1">
        <property type="entry name" value="LD15586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="301" mass="34411" checksum="9E13711C9DAFA1D8" modified="2024-11-27" version="1">MSHFLRQFHIISSLKSNSDRDLYPFYKVIAPILAKHPAVRKMHTQSINRNLQLKLVDEPLNETKKKPLAVILAWMLAKESHIEKFRSIYISRGFDVLTVNMAPKDLLFPASGSQVVAKSVLDYFSTHENYDDILVHAFSVGGYLMGEMFVQMRKDAEKYKDITSRIRGVVLDSAVDFEGIPTGFPRAVSKNPITLKVLEWYVSTHLALMYNVATKHYLTSSKNFHNTPLRCPALVFVSEADKVGSPVANQMVVENWQVRGVDVRVKCWKDSKHVSHMYKYPEEYVAEIDNFLSKINLSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W1L4</accession>
    <name>A0AAV4W1L4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_270748_1</name>
        <name evidence="2" type="ORF">CEXT_519821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015393">
        <property type="protein sequence ID" value="GIY75809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W1L4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="29445" checksum="6682EFD39DFE3B40" modified="2024-11-27" version="1">MIAQAPFTIHFHNQKVKDYEFDDTSNRHIPSNVETERGISLLKRIFTFFSINLSTKVSPSSTCLQLLQLITLTNMYIAYLILIDIRSYFMMNTSLGLSISLSSGTIIIVALRLILLTHLKLIRQSVRMSYDLLCTIHKGRCPSIMPCIFFQFRNLYCNNKTNRTAMVLFYILASFLECMDMITMYTFPGMVLILCTYQFSIISELNKALARRIKDSYSMKEAIEEYLAFYAEVQLVMKISERAISPIVFLCTPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W1Q3</accession>
    <name>A0AAV4W1Q3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_468381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015447">
        <property type="protein sequence ID" value="GIY76183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W1Q3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="12889" checksum="ABD058CD61759B8D" modified="2024-11-27" version="1" fragment="single">WKCTQHFSNEGSHKKRENIPPSAAASPLSPTKEHPAPNEIGIEPGNSNEWAGKRRASFKITPVQIKEGGGGAENDGDINRSRWADNKGVGRGSAGGKNRLNNSWSRPVVSGALCLNLYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W505</accession>
    <name>A0AAV4W505_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_785491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015686">
        <property type="protein sequence ID" value="GIY77812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W505"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9672" checksum="4A272335D9272EEA" modified="2024-11-27" version="1">MRSLLIQSTRVPGCSITAVLMSSSTCDVTGLCLLQLHLSVTSSLADILNHDIMYRTPFQTLVHGMDSSCIENHESQPLFWFFTTDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5E8</accession>
    <name>A0AAV4W5E8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ATM</name>
        <name evidence="1" type="ORF">CEXT_751331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015580">
        <property type="protein sequence ID" value="GIY77129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5E8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="428" mass="49789" checksum="6F8D972C1390CB21" modified="2024-11-27" version="1">MFQSIANKYNQIKYKSGKLSLEQEITLFLKSYKMIGKATVNGLQYLCRQLKTRQTELLEMLNSIKIQKAASDCMGALVIATLLTARDATDIITQFLLPFAYKRSWLREQLILFDPERIDVKVMTSEILKELFGTRTAYTFFIDYQALYPNNHIKKYAIPFFSCQNANNLKSVCQYEYKVEDIQDLSVWIPITSEHFEWITNLVCTLIESGLTKDNFYECLIPLCRKQVQFSEKILPYVIHAILLKKSLRSDHSSDHSDSSDTYSKIGDSDAISGCEVVATDSQAILKHTYLTEKKWDGLLKISDLNNSTLEIYRLLQQNNLNSVLQGYIQSLIHTQDEKLLDNIREYRCEAAWRMGQWDLPMPKRFQECLYKCQQSLISENSVVFEKYFKSAQKTQFEYLRHTSLEAARNVFTCLESYSDALYIGRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WA07</accession>
    <name>A0AAV4WA07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_766191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015913">
        <property type="protein sequence ID" value="GIY79641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WA07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15349" checksum="E5394E42355A0E81" modified="2024-11-27" version="1">MTIYVDEKYTNTPDSIVIIYQYPEVIKKVPGNDRLHNSRVNSPTINIATYMLFKSCGNMREFQNTIELAITHQNSSHGKDLETFILCQLSTNCKLPWQLELDNSDQVSPIFTSGNFCWVFRIISFAIGQGFSDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WKE9</accession>
    <name>A0AAV4WKE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_190215_1</name>
        <name evidence="2" type="ORF">CEXT_596021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016374">
        <property type="protein sequence ID" value="GIY83361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WKE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051109">
        <property type="entry name" value="MAM_complex_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14063">
        <property type="entry name" value="PROTEIN LIN-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY83361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11395" checksum="DFB05B7C55093301" modified="2024-11-27" version="1">MAFQRPFLISLKRSDSSNRWGFGIKGGSDYQEPLRIQSVIEDSLAEKSGLREGDEVIQVGRVNVQDLTLGQVHELLARCGNKLKCLSSGEDFRFFPISNCTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPF7</accession>
    <name>A0AAV4WPF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_427551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016378">
        <property type="protein sequence ID" value="GIY83400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="17802" checksum="32C3BB3A0B603B96" modified="2024-11-27" version="1">MSVRFSVAGGKLTKSIASDELTKQQKRKGNRNHFAYHIGIRQSSQTPTTIPDTQLWTPFRRIIHHEAVKPLPISSTLKHAAPNRILTVDNLLPSGQSIRQHPPIIRSTRCPFPRRGFNMLFNQVAPPFFLPHEGKGEGLSKTIFQNKQLEMTSALGSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQP8</accession>
    <name>A0AAV4WQP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_158041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016489">
        <property type="protein sequence ID" value="GIY84241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10881" checksum="49C28A5ABCA8ED06" modified="2024-11-27" version="1">MPRGTSDADRPLLVAMTPWLDFAIIPSQSCFALNFDSALLYPRMRDETERKGVKSLFAANRCLCLNRRVRRCFASSPNGNFFRVPLNIVIKIVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWH6</accession>
    <name>A0AAV4WWH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_36691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016709">
        <property type="protein sequence ID" value="GIY85893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9537" checksum="8595263B737DD5FC" modified="2024-11-27" version="1" fragment="single">VRNKYWLAKKNLCYERFVCTLRDYVLWSQAVNGFHLVVECNARRLVAFTFTLVEYLKAKSTCAKPKIRDSLHDSFAYSRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7P1</accession>
    <name>A0AAV4X7P1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_154841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017265">
        <property type="protein sequence ID" value="GIY89823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11285" checksum="93ED405D89323968" modified="2024-11-27" version="1">MNIFPHTSEVPSSLHLACEVIQKMQTGDLFEDVPYLSFRSAKDGDEHLEREDHTCSTLLKSFAVTCRSAHALPRHVGDIPSEKMAIANNKEIKRGGFKICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB29</accession>
    <name>A0AAV4XB29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_271771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017435">
        <property type="protein sequence ID" value="GIY91628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="62" mass="7373" checksum="3A04D11159E178B5" modified="2024-11-27" version="1" fragment="single">STAVVESTPRWSSEERSPRWISPSHSSFRSERKRRRQKTRLLTSAFQTKLRMTGIKHLSFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB88</accession>
    <name>A0AAV4XB88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_198681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000013">
        <property type="protein sequence ID" value="GIY91460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14555" checksum="2B8F7FA1A6C8B55E" modified="2024-11-27" version="1">MNGNQTISSFPYIFSTQMVLLEECRTRTNPPPNTTGITRGHATSKRPGPELFRSFLSYFLRSEVKNSIKLSRTHRPICVKGIPGRSNAPDRFLPFTSSPPPLSTPSRSFCSEQSSRRLTLFDAFCRDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBM9</accession>
    <name>A0AAV4XBM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_80131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000091">
        <property type="protein sequence ID" value="GIY92083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17732" checksum="8538E0F92C401A6D" modified="2024-11-27" version="1">MFSQKLPDISASKFERNISKVKQKSNEISNLDNRDLIFVGERNKNDKEIEVIDLSSDDSDDCNVKNVEKPKCAKDAYTSVDITVNESHCDKSVGSSDVEVLDDSPSLLNPSNVRKDSLHYTEGSRTKRKCSENEKFPSKNLLSAMKKILMTNLRNMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCP4</accession>
    <name>A0AAV4XCP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_43391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000136">
        <property type="protein sequence ID" value="GIY92402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11479" checksum="AF1603771E61FFBF" modified="2024-11-27" version="1">MVRQSENIKNQLKTINESFPEINITLSGELLKIYSKESDEHRKITQFLKNSNMDFFLITPTMKGPLQQLLKDFPAPPSPLKSNKNFPPLNLLTLITKPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDN7</accession>
    <name>A0AAV4XDN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_777271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000222">
        <property type="protein sequence ID" value="GIY93026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY93026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19237" checksum="9762EFFC28333F2D" modified="2024-11-27" version="1">MPGVIDKVMGKKKGVDLIVFLFSLWDGAAVFIIWDENLCFFPLPLGELSICARYRCIVPGRLPRGSPSRDVCRVILDKIPNSKEQYQLGSFPEGISGAGPGEGAREYPARIRGHHPALCARIPGQEEVQEHATGRRQVADVIQGLDRQAPVPSSKGHHHQNAGYYPNDTAEKGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH11</accession>
    <name>A0AAV4XH11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_150361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000226">
        <property type="protein sequence ID" value="GIY93049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16909" checksum="705987D32EB507FC" modified="2024-11-27" version="1">MFRLTAVGSLGSKVTLTPNLSGKSKSRIIDSMKNKILQVKSDQTPDPVEHEENEAETSNKISMEAKSSIEASRSIRHLVYRIHMYFNPTEYSLLFYQKEPSFSPEDLDRYNLYFQYARLQDSHVFQSDGILITFLSEVNLLLARGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHQ7</accession>
    <name>A0AAV4XHQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vesicle transport through interaction with t-SNAREs homolog 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">VTI1B</name>
        <name evidence="12" type="ORF">CEXT_624641</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017664">
        <property type="protein sequence ID" value="GIY93480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903076">
        <property type="term" value="P:regulation of protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15890">
        <property type="entry name" value="SNARE_Vti1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000002">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF89">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="124"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY93480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="223" mass="25220" checksum="78C5DEB105EA8FE6" modified="2024-11-27" version="1">MSSQKFESLEDDFIASRGKLTSKIEDLTARSAGQARKNLAREIQRDLDDAQGLIEDLEIEIKAAPYPFRTQMNNRLKGYRQDLNLLKKKVAQSENSAASSRNQLLGTTQPSTSPFSSASNNRGRLLQINDTINRTTESVNRTQQIAAETDQVGIAVVDELGTQRESLIRTKERLVDTDANLSKSRKILRSMYRRVMTNKLILIVIILLEIAILCGVVYYRFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK69</accession>
    <name>A0AAV4XK69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_93979_1</name>
        <name evidence="2" type="ORF">CEXT_328181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000375">
        <property type="protein sequence ID" value="GIY94336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="25298" checksum="86C6C9A4419E07AA" modified="2024-11-27" version="1">MLDMNFVDFLLQDKQILYHHMVESSQKAITSGHDLILVHCGVAETRNAKPLTIQKHLVLKNSRLTVKNPDYRHWNLHIHDVQESDRGGYMCQVNTVPMKSLVGFLDFRHLSWTPRRALRCSLAKAPTSPCRVGSGDTRPHHHLEEGGRTDTNDQHLSAPDRRSLSECKSVAAGCPADLTFFGDKKASNGVSSISLHFSAIILLQYRKLKGKAYEKRIIAPKAIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT01</accession>
    <name>A0AAV4XT01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_702231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018265">
        <property type="protein sequence ID" value="GIY98171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9631" checksum="365C6251EAFDAA53" modified="2024-11-27" version="1">MFRPIPADAPAPPIIIVCEKPSQGRMPSRLPDGSQVVLTSAVCHSPLAFAILFLVRSRDIRQIHSHTSDVLFNQSETLFHHHHRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVR1</accession>
    <name>A0AAV4XVR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_425751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018323">
        <property type="protein sequence ID" value="GIY98668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24393" checksum="558A70FA1029373A" modified="2024-11-27" version="1">MLANSSMSEGSLSKILAKRTVVTSIDLQEWPRRQRPAAYVPAGERASCQTHSPARLPVDWRGRSSTAALRCPTRHWEDGGHPLPPLSTARRILNRYSSLAKCFKHQRNYDDAHGKDKKFVWANKNFENPSQIPFVKLQCKKPTRATPYKKNRYTRYKWILFFSSVPNSPSSIPLKMEGNKYLRYYNYAPPFCMFRKSPFHPPLSVYAIREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWJ6</accession>
    <name>A0AAV4XWJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_321651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001056">
        <property type="protein sequence ID" value="GIY99516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12812" checksum="20BBC939AC926DBA" modified="2024-11-27" version="1">MWVKFCLQNLDRKPPKVMIETSSALSREQGSPYTILIPSSLELMWRCTVLRMLWVMLCQHNLYRKNSKGAEPFFIPSLQQEVFELLEFVSKIYKIESKMENLCRKCAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYG2</accession>
    <name>A0AAV4XYG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_406831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000993">
        <property type="protein sequence ID" value="GIY98986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11406" checksum="2AD2B23B65150A0F" modified="2024-11-27" version="1">MKNGHNGGMDMTSSSLLIQPQQSTHKRGKKKKERVQETDTRQIAKAFNSRSEDIGSRDSHAHFFRFCGNGSSTQLTAGDRRVLKELFGERRGRLKIACQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZK9</accession>
    <name>A0AAV4XZK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_783161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018419">
        <property type="protein sequence ID" value="GIY99391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020858">
        <property type="entry name" value="Serum_albumin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48552">
        <property type="entry name" value="Serum albumin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY99391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10824" checksum="2A056C8E40721131" modified="2024-11-27" version="1">MHINGQECLMPIDALHPAVCDDVDDVEQKLPICCVADDVPNKTCLNALNKGERLRTTDHLAADMGKRINRFNTCKTVSWLDNVLGSSRNCWEILVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZM4</accession>
    <name>A0AAV4XZM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_783251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018419">
        <property type="protein sequence ID" value="GIY99406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="18025" checksum="6693C14584E32094" modified="2024-11-27" version="1">MFQLMDMSNPSCLTESSAVTSTSQCQKGLLPPRTMRCVPSQFKFGPPPKVSWRNGFVALQQQPRCVILEEFMLGIKFRLRAEDKCDFQLYRGGGIHQRGERREVRVLVQSLEKAEINFTVLPIPSCYEGNLKLPDNTDSFHCNANHWCDARRIHVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6B7</accession>
    <name>A0AAV4Y6B7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_160871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018862">
        <property type="protein sequence ID" value="GIZ02802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6B7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9251" checksum="088357AFA1443B87" modified="2024-11-27" version="1">MRMHSIPWRISFKEAGDNVVGGDGYRIWQQVVVETEMRREMRVGGFVDDMLTRGIITSGDKLGQVLNTIFYSVMGSQIVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7G8</accession>
    <name>A0AAV4Y7G8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_344111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018896">
        <property type="protein sequence ID" value="GIZ03048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7G8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7506" checksum="5BA2953BD7BB6EEC" modified="2024-11-27" version="1">MSLVATELCGSEVQTEDHIPVSLEEKRPGRVTSASHVRLKEEEEVKKKKEAQEVASSMCGCTTRGNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDP7</accession>
    <name>A0AAV4YDP7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_126662_1</name>
        <name evidence="1" type="ORF">CEXT_554791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019230">
        <property type="protein sequence ID" value="GIZ05175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15713" checksum="C011B8AD55FC308C" modified="2024-11-27" version="1">MDQLHLNVRNTASSVALYKQGRQRDLGRGFRSKKLQAPPKCRIVEPSVPFNLLTPTTVLSNVTFNEDLKVKFHEEHPELRQLALVIINNISPRALVIYTDGSKSDSGRTGSEIFMKTSTGEFRYRFRNRTTAQYSAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4V8</accession>
    <name>A0AAV4M4V8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_725951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001855">
        <property type="protein sequence ID" value="GIX67157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4V8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="248" mass="28167" checksum="DCD5367650DB01A4" modified="2024-11-27" version="1">MSQRMGRDVPCRKKKEHYPLIVCFQFWFTTPMGDESVIAYSTSRHGDGNGERGGASEMDAEKTQKGWVTSLVITITATFVKLQSFPNKTKIYALSSQNGLLSTNSEISTKYRDHQIACHNDPTLRLGKSAEIVASGRTKEKKKYVFLPEKKGKEMSSGGSEKRRRKMKSVSFHSMWDVPKDGQGRAKQEKRRALPADCLFPVLVYDAHGRRKRYCIEHLETRGGNGKGMVPGKWMRSDLRFAPRVQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M830</accession>
    <name>A0AAV4M830_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab GTPase-binding effector protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RABEP1</name>
        <name evidence="2" type="ORF">CEXT_278821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019446">
        <property type="protein sequence ID" value="GIX67932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M830"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015390">
        <property type="entry name" value="Rabaptin_Rab5-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09311">
        <property type="entry name" value="Rab5-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rabaptin GTPase-Rab5 binding" evidence="1">
        <location>
            <begin position="59"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="20207" checksum="C30BF18D44D8E253" modified="2024-11-27" version="1">MYVSVWDEGKDDKTLIEHQKFWDLETLKIKDDPMDKKLYDKDMLEQFEESMKFKDWRYEIKSTYDVCHKELKEYQTTVVVERDIFKRELEKVQNENDVLLGKHIAKAQQMRNEDINLLDTTEELRFYCLQKQEEFVTIKAAERELQHFAKIVKELKLQNFISSQGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8C7</accession>
    <name>A0AAV4M8C7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_648701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019508">
        <property type="protein sequence ID" value="GIX68618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8C7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043685811" evidence="1">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9342" checksum="9551BEB699D40872" modified="2024-11-27" version="1">MFFFSLRTSLLFWKALEWNIFKISNDCIGRKKHSSASRKAPINRLLTSHPGNCPIDEQENVLGTIDQLRISLTRSFDMDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8Q5</accession>
    <name>A0AAV4M8Q5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_507341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019472">
        <property type="protein sequence ID" value="GIX68268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8Q5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10587" checksum="F7AA518223512A95" modified="2024-11-27" version="1">MAIFRIILFGDAKQKKKIQIFMLPPPTLCCKGYLRGRMGGSAEYCEWAKAHHHFNLIRFLKQHSNIHSGIPQKCLQRLSGDFIGRWGCEPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCJ3</accession>
    <name>A0AAV4MCJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_69271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019646">
        <property type="protein sequence ID" value="GIX70073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10792" checksum="8872887FC2BFE06D" modified="2024-11-27" version="1">MSSEICKRRRFGFAEQQCLACLSWLNAALFTDKFVSWITARSSALYIELVSRKCIGTSLKRGVGAEKRSSNCRGWFRISEFALIFRLAMMAAEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHL3</accession>
    <name>A0AAV4MHL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019702">
        <property type="protein sequence ID" value="GIX70931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14113" checksum="1E77E1657B287B4D" modified="2024-11-27" version="1">MGGAQSFPPEPHPCLPFPKSLPILGHSDNAHRREHNIQQLAIGSYRMVLARRELQKMMAKAWSERFVKFNKLAEATWRKPFQFGSLIRKVQKVRQVAEATWCEPFHFGRLIQKILEFRQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJW9</accession>
    <name>A0AAV4MJW9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase aspartic putative domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_705031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002341">
        <property type="protein sequence ID" value="GIX72706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21970" checksum="4A43AA6C68CC8666" modified="2024-11-27" version="1">MVHRPESIRKKLKFTRRFLEVFLKFTRTGLCLDTGSSRTFITRGLTRRLGLQITGQEELKFIAFGGKEDTQCRLLLDNHFAGKYKRLSPTVVLNETKFGWTLHGQFSNSFNSKDPINAMHVSVCDEGKDDKTLIELQKFWDLETLGIKDDPVDKKLYDKEMFEQFDESLNLRIGDMKLNFLENLIISII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MK52</accession>
    <name>A0AAV4MK52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_618191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019872">
        <property type="protein sequence ID" value="GIX72713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MK52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8592" checksum="EDCF99E339968750" modified="2024-11-27" version="1">MNGAVANQFNRSIIPDVFVPKLPASFEKQAIPAKNRNIAGGRRFDEPCYYYHFWITTRACHQWSLQLYSIVETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNB2</accession>
    <name>A0AAV4MNB2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exosome complex component RRP45</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Exosome component 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Exosc9</name>
        <name evidence="12" type="ORF">CEXT_194311</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002363">
        <property type="protein sequence ID" value="GIX72971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="10">
        <location>
            <begin position="40"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="187"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="360"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX72971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="446" mass="49504" checksum="CB146BD0FEBD06F8" modified="2024-11-27" version="1">MKVTSIVEKDFVNSIIKKRKRLDGRNLTDGRTLNITFLLEWGGCIVHLGNTIVLAQVSAEVSEPRAVSPTEGALHVNFELSSMSAPDINLSRSSSEFVETQRSLERCIRDSKCIDLESLCIVAGAKVWTIRVDLHAMNLDGNVLECASIAAISALAHFRRPDVTVVGTEITVHSLDDREPVPLNLHHMPIAINLALYDQGTYILVDPTDVEERIAEGCYIVGMNAHQELCFVHRRGSLLLHESTIQKCEEIAIRRAQIVTQAIRSALDDDSYKRTTKVPIGLGSLLQTGTILGAKQPIYNFDINSVKSHVNEIEMQEIDSDVITIEYEKPPKSQTVVVSAAKEKALKILSEAETSVFEGGTSKWSIDHEEEESTSSEEEPTVPSENLKEEPIIPSKNLKEDPIVPSKILKEEPDSSSEEESAFMEGDQVDVKKSVVREWYSKNPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR29</accession>
    <name>A0AAV4MR29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NDUFB8</name>
        <name evidence="3" type="ORF">CEXT_678891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002535">
        <property type="protein sequence ID" value="GIX74896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008699">
        <property type="entry name" value="NDUFB8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12840">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05821">
        <property type="entry name" value="NDUF_B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX74896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="16274" checksum="FA77CDF3611DBB0B" modified="2024-11-27" version="1">MLQKNKPITWNKDWKPGPYPRTKEERITAAKKYNMLPEDYEPYPEEEGYGDYPMFEKFHMESRNPFEAYDYPELKRNYGEPVHPDYDICLEDKVNFQQKFRTPIYKQLLYVVVAVSLYTGLILYGEFHPTDTKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY08</accession>
    <name>A0AAV4MY08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_736091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002681">
        <property type="protein sequence ID" value="GIX76608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12213" checksum="14A2D8726E3A22B9" modified="2024-11-27" version="1">MAKRAKILLINGAPFCVAALSPLKHGREEKGIRLILSGKAGKPKDNPGKGLLGVRTRISELTSAPGLLLAFLVSLSSNSRQHLPQLYESTLFSHIILKDLHFLSRNIFITSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3W8</accession>
    <name>A0AAV4N3W8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_48541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002834">
        <property type="protein sequence ID" value="GIX78371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3W8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9009" checksum="6CC499BFEEDEC62E" modified="2024-11-27" version="1">MGKGGGCDDFVNAAICTKYEHLFLLRGPLLRTDASLRSLSPAKIPHEAPLLGHPFCCGGRCLPIMSDTARFGVSSSAFLFLPPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5E8</accession>
    <name>A0AAV4N5E8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_543591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002987">
        <property type="protein sequence ID" value="GIX79929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5E8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="19762" checksum="829CF3AA36FCCD6E" modified="2024-11-27" version="1">MSVSKDSKITSAKLPSLGKVVGRKTFFIAFEHYLLNILNVLNFKHNNETSGLRVVNKSTFNLLDHQAPANAVRLVIGQRFTLQSLTPRWRRAFKVSQWLKPDGFPSSWADEEKGGGTSVAHLVMFLGQHALAMKVRAAERPPEEIYVKVIRCLSKGLAGQDNNTSIWITSVSTKINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6X3</accession>
    <name>A0AAV4N6X3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 4V2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Cyp4v2</name>
        <name evidence="11" type="ORF">CEXT_349831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003048">
        <property type="protein sequence ID" value="GIX80590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6X3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20628">
        <property type="entry name" value="CYP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX80590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="504" mass="58448" checksum="8B387A4FA387067B" modified="2024-11-27" version="1">MFFEVVVCAFIGIIAVLAILTLWKKKYSRFVPDNTHSVFKALVDVMDSILFVTSGKKNALHIYIMKYFKEKSKKFKQYPLFTHWLCGVRWVFIHKAEAVKELLKEKRIIEKSDFYDFFKPYLGTGLLTCPSSQWKERRKLLAPCFQSSMLKGNLTVFNEHAQKLVEFLHEETDKEFTCVETPALCSLDVVCESILGVKIGALQSEAEEYVSSLHRLLDVAMSRIWKFWQWPDFIFHSSKTYRENLQYLRIAHGFSRRIIKEEKLRYMNKEMGHVSRRPKCLLDVLLKMHIEDQVLDEEGVRQEVDTFIAAGHESTAVTAKWALYLIGLYPEVQEKIHQELDSVLGSDSKGPLSIDHLKELKYLDCVLKESHRLYPPAGAIARKISEDIIICGYKIPKRTHVIVAPFFVHRDEDVFPDPEKFDPERFLPENSAHIPDCAYIPFAAGPRDCIGRVFAEMEVKILVCHILRSFSLHSLDSRDQVLPLIKLSLQSSQPARIKFRCRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAR9</accession>
    <name>A0AAV4NAR9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fatty acyl-CoA reductase</fullName>
            <ecNumber evidence="1">1.2.1.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Far1_0</name>
        <name evidence="4" type="ORF">CEXT_430721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA</text>
            <dbReference type="Rhea" id="RHEA:52716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="EC" id="1.2.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the fatty acyl-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.84" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01020712">
        <property type="protein sequence ID" value="GIX81767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102965">
        <property type="term" value="F:alcohol-forming long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080019">
        <property type="term" value="F:alcohol-forming very long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026055">
        <property type="entry name" value="FAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011:SF45">
        <property type="entry name" value="FATTY ACYL-COA REDUCTASE CG8306-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011">
        <property type="entry name" value="MALE STERILITY PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="3">
        <location>
            <begin position="27"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX81767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12765" checksum="C2E432B6CC679E4C" modified="2024-11-27" version="1">MQTEMEDEAYSELTPIQKFFFGRSVFITGATGFVGKVLVEKLLRCCPGIGMLYLLMRPKRKRTAEERLDKLFQAELFSKSKRSASPFSKESASHRWRSSERQARDFGRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBR8</accession>
    <name>A0AAV4NBR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras-specific guanine nucleotide-releasing factor RalGPS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RALGPS1</name>
        <name evidence="5" type="ORF">CEXT_79581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003163">
        <property type="protein sequence ID" value="GIX81765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13310">
        <property type="entry name" value="PH_RalGPS1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="59"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="399"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX81765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="526" mass="60521" checksum="087D2E0A31DAC198" modified="2024-11-27" version="1">MKYCEIATEIACANMNSYNKNESFNCISNSHESLDTRWNGDVVHQKSYDAVVFSVLKVAPEDFASQLTLMDFLVFKEIQPEELSSCCWNKKEKMTYAPNVVAFTQRFNHVSLWAVKEILSGQTPKARADIIAHFIKVAKKLHEINNLHSESAIISALQSAPIFRLSNTWSQLSKKEKSSFDKLADVFSDANNFEKLRDHMTNTKLPCIPYLGLFLKDLVFIDIAHPPTQGLDNHHRQMKMNNILRLIAEYQQSVYDHLPVLPHVQNYLRSVRYIDELQKFVEDENYKLSLELEPMKSSPNLRDSNSHRHLVTEDLKEGMELRNKCHVFLSVDTLSTCSTFSSERHLLDDSILEHPPVLTRKRSLGSIEDIHDHFDTWLEHLPLNSSEYQEINLRHIDSVATFQGYVRRKTVLKEGKKPAMSPWMRYWLVLKGTTLIYFPPKTLRGTDKSDFKSTPSKSIDVSGCIVICSDAGNQPDAFQLTDPAKGNVYKFRTGSPAKTVQWYNCLRKATNQYDECTHLENLMTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBY6</accession>
    <name>A0AAV4NBY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_681731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020760">
        <property type="protein sequence ID" value="GIX82232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15427" checksum="E8C1BE6A58D51C62" modified="2024-11-27" version="1">MSNIHVFHLYRGSDFVELRLDLVLGTTLISASTLKKYLPLDFGGSCCRDEKASKTAQKLSFLRYSTFKKESLKDDTEKPFDCLLRSLTDIQVQHHANFEACNAKKGIQKRKGVKRKNTDSISIFLAQNLTKNLKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDP6</accession>
    <name>A0AAV4NDP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_134121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020715">
        <property type="protein sequence ID" value="GIX81806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11658" checksum="C9532B730E6D0AFC" modified="2024-11-27" version="1">MVASTNDSSQNDEDDDYYEETLGGENDEDSDELPFSEVKLLRKGRISVRCTAYLSNSARYARFYCDWYIKKPSRILKELQQNLEKFGQKCEVKNLEPSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE24</accession>
    <name>A0AAV4NE24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_441061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020831">
        <property type="protein sequence ID" value="GIX83079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9444" checksum="0F943EAE35FE61E0" modified="2024-11-27" version="1">MEGETSTGGNRRLPFLSHNGRPREFPKIRPTALLSLVQKHDESCFRAAGECATMDSPMHKRFIQPYYGGRLSNCRLHPLPQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE87</accession>
    <name>A0AAV4NE87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_251451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020824">
        <property type="protein sequence ID" value="GIX82963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13927" checksum="921AB9851FAEE2D1" modified="2024-11-27" version="1">MKDRQRGGMCCVWHMGGGRPRDFSLPNHHSPVWFTGVYPSAGTVTPRLSSRLSNRLPQITVCSPSPQDLVTPPPLSRPLVHPCAPGESIVYSPTEHFRFSPPTTHTLFEHRTFRRKSHERPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGK1</accession>
    <name>A0AAV4NGK1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Ppid</name>
        <name evidence="9" type="ORF">CEXT_801081</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01020784">
        <property type="protein sequence ID" value="GIX82467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000025">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP19-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000029">
        <property type="entry name" value="peptidyl-prolyl cis-trans isomerase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4 7" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="293"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX82467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="363" mass="40877" checksum="57C73042CC49754E" modified="2024-11-27" version="1">MSAPMCGNPHVFFDIKIGEEKVGRIIIELFKDITPMTAENFRALCTGEKGIGRYGKPLHYKGSRFHRRGDCINGNGQGSESIYGETFEDENFTLKHDQPGLLSMANRGPHSNGCQFFITTVATPHLDNKHVVFGKVKKGLGVVNEMENLITEEDEPLEPCIIENCGEFEGGEDFGLNESDGTEDTYAPFPDDCELNFKDIDHILYVAGQVKISGNAFFRKEDYITANMKYKKALRYLNKLHEINEVDYDLEKRLNTVVLPCILNSAACKLKLKLYDRALEDCDEALDIEAKNPKALYRRGQAFHGKGDYDRSLADLQEALRLAPHDKSVIAELAAVRGEMQAYKAKKKGKHMLNFSCKNFMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJT9</accession>
    <name>A0AAV4NJT9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LRRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_57640_1</name>
        <name evidence="4" type="ORF">CEXT_776351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020901">
        <property type="protein sequence ID" value="GIX83744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJT9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF211">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043394235" description="LRRCT domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX83744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27466" checksum="56DE76113467A890" modified="2024-11-27" version="1">MKIATLKLLLLSLYNDLLFSLHYDFFHWKWISSIRCSNERVFSSDCEMAFGEEIEFLTSVSTPQEFYEKDELTGLHLEGNRIATLGSEIPALTKLKILSISNNQIRTISTNELPPKLTQLYLAGNPFLCDKQMLPFLQFLNSTEKLTTDEDLCTPSQKGTAPASPALHPCRCSRTNDNIIFADCSSSGLTNLPPFFTEEQVNATTFYLKARSFEIHRLRIEFRHIRGNGDESTLFTPLHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLS2</accession>
    <name>A0AAV4NLS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_527631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021001">
        <property type="protein sequence ID" value="GIX84783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10443" checksum="12908639D203CFF1" modified="2024-11-27" version="1">MSPSLLRNMASCLSGLHSEASKREVQQKADRLVQIKEGDERESQPHAHVAADVAEHLHALLEKGEFSVKISVQTLYWIISQVVVALIQLAIRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQA6</accession>
    <name>A0AAV4NQA6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Electron transfer flavoprotein subunit beta</fullName>
            <shortName evidence="8">Beta-ETF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ETFB</name>
        <name evidence="11" type="ORF">CEXT_577121</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase. Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role.</text>
    </comment>
    <comment type="function">
        <text evidence="8">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer composed of ETFA and ETFB. Identified in a complex that contains ETFA, ETFB and ETFRF1. Interacts with ACADM.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021099">
        <property type="protein sequence ID" value="GIX85871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000011">
        <property type="entry name" value="Electron transfer flavoprotein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294:SF8">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="10">
        <location>
            <begin position="41"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX85871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="270" mass="29579" checksum="AC6BCDAF5A9EA631" modified="2024-11-27" version="1">MNLDNDRHIIVYHTVIVIAEIVHVLFNVQFWLCTVHIKPDKTGVVTEGVKHSLNPFDEIAVEEAVRLKEKKLCSEIIAVSCGPSTCQETLRTALAMGADKGIHVEVAGNDYETLQPIHVSKILAALAQQEKVDLIILGKQAIDDDANQTAQMTASILDWPQATFASKIEKDDGNLKVMREIDGGLENISVKLPAVVSADLRLNEPRYATLPNIMKAKKKPIAVKKPSDLGVDISPRIEVISVEDPPTREAGTKVESVDELLGKLKSLGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXK4</accession>
    <name>A0AAV4NXK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_778991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021431">
        <property type="protein sequence ID" value="GIX89491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005312">
        <property type="entry name" value="DUF1759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22954:SF3">
        <property type="entry name" value="PROTEIN CBG08539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22954">
        <property type="entry name" value="RETROVIRAL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03564">
        <property type="entry name" value="DUF1759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17861" checksum="982536F9EE28E972" modified="2024-11-27" version="1">MNLMLLETETNTADLDAETFAADEYNKKFKRINIIFKSKIAVIGTKKFGGEIKDWLPFWGQFSKIDSDSNIDEADKLQYLIQATLPSTRARELVESFPPSKENYHKAVDSLKSRFGQDDLLVEFYVRELLKLTISMNSRDQKVKLPTLYDLIETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P059</accession>
    <name>A0AAV4P059_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_126521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021500">
        <property type="protein sequence ID" value="GIX90403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P059"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13061" checksum="02CD38672FB51CA0" modified="2024-11-27" version="1">MLCENDTVALKVETHSKNMQPSVEMDSLLLIQKQPNSVILSSANSIETENTNGCHPRRNRPTISFKEPSLKGKSFSKDEKINIQRFKYPVKQKEYHIYMLNILTFVNIHNDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1U9</accession>
    <name>A0AAV4P1U9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LIM domain-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LDB2</name>
        <name evidence="5" type="ORF">CEXT_530951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the LDB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003902">
        <property type="protein sequence ID" value="GIX89975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1U9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030274">
        <property type="term" value="F:LIM domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041363">
        <property type="entry name" value="LID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029005">
        <property type="entry name" value="LIM-bd/SEUSS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10378">
        <property type="entry name" value="LIM DOMAIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17916">
        <property type="entry name" value="LID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01803">
        <property type="entry name" value="LIM_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51957">
        <property type="entry name" value="LID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LIM interaction" evidence="4">
        <location>
            <begin position="199"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="150"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX89975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="303" mass="33450" checksum="0A06347C991443F7" modified="2024-11-27" version="1">MNAKDEMKRMSFENKGLGGQYPNDPMKDQIVKDNAVVVCTEGRLILEFTFDDLMRIKSWHFATRQHRELVSRSLIAMQMSLHMEAQQQDPVLLEQLSKNITRQGLTNSTLNYLRLCVILEPMQELMSRHKAYALSPRDCLKTTLFQKWQRMVAPPETQRPPSKRRKRKSSAANSGGANISGKKKNISPGPPNFTLASQDVMVVGEPSLMGGEFGDEDERLITRLENTQYDASAAAAAANGLEDNEDFTSNPITSVPSTTGAPPPTTWSNPPSAGAPSSERTTVSAPSSSSQPASQEEKNLLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6K5</accession>
    <name>A0AAV4P6K5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Homeobox protein SIX4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SIX4</name>
        <name evidence="13" type="ORF">CEXT_444131</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021592">
        <property type="protein sequence ID" value="GIX91565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000085">
        <property type="entry name" value="SIX homeobox 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031701">
        <property type="entry name" value="SIX1_SD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10390">
        <property type="entry name" value="HOMEOBOX PROTEIN SIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10390:SF44">
        <property type="entry name" value="SIX HOMEOBOX 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16878">
        <property type="entry name" value="SIX1_SD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0371">Homeobox</keyword>
    <keyword evidence="8 9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Homeobox" evidence="12">
        <location>
            <begin position="252"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="9">
        <location>
            <begin position="254"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="48"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="294"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX91565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="418" mass="46381" checksum="8B25A7F9B152C71F" modified="2024-11-27" version="1">MSGLQTESASCYGGESRQTTPHSMRYQNDGIDASTVGISAANIAAVARSHHGTTNRRTAPVIHSGSIQGRSGISGTPNGTSSSNCGVDYTTNNNSDSSNRTSSGGSTEYCPTKSPSSKLNDMLSGQNLTFSSEQVACMCEALQQAGNIERLGRFLWSLPPSELLRGNESVLRAQALVAFHRGNYKELYTILESHNFDQKYHNDLQQMWYKAHYREAEKVRGRPLGAVDKYRLRRKFPLPKTIWDGEETIYCFKEKSRIALKECYKRNRYPTPDEKRGLAKKTGLTLTQVSNWFKNRRQRDRTPHHYRSDSSLGHHPRTSTPHLCVGNSHIVSPGPHISTARSSPASSQAALCGHHFGEDMARDFHFNHSKSMDELAVMAMVKSEPGIYPSTLVYPTNSVAYDTAATLSHLHATTMNHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P737</accession>
    <name>A0AAV4P737_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_93861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021612">
        <property type="protein sequence ID" value="GIX91775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P737"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043697050" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21185" checksum="3310D73BAF332C48" modified="2024-11-27" version="1">MGSLFVLLLGCRQLLGAFDSAPTKIEKKVFAPLPGCTMVRNHPLMMKVLLYGDVDDRMKCLFVGICGRYGILAKILLLALLPGFNHLLCFFCASSERGREGGRLISIRSSEFATIHHGCPKWVPFFVLLLLGCRQLHRCIHSGPPKIEKKVFVLPECTMTRNHPLMMKALLLVNVEALLIDEDDVKMFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCZ5</accession>
    <name>A0AAV4PCZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_530601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004447">
        <property type="protein sequence ID" value="GIX94903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11752" checksum="81ABFCE826C7E6E9" modified="2024-11-27" version="1">MYLAEILNPFSVNKYNNCNPFNCNFSRLETINSHGLASNPKLFYCSSIEKELLSHQSWKDPLDEWICLETSLHRLDGKNHLSSSALSQLATTLLYRTSLFPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PIS3</accession>
    <name>A0AAV4PIS3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_729061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004563">
        <property type="protein sequence ID" value="GIX95789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PIS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="9911" checksum="4B2D94039098ACA2" modified="2024-11-27" version="1">MSIIVMKGYSRGGGLLRERMTCRSGTIKGNGRCSVLFGPNIRPLFLAARPDIASAGRDLSKQHTKKNSLVFIFAIAFGVAVITLGNVKKTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSL3</accession>
    <name>A0AAV4PSL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_533281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004875">
        <property type="protein sequence ID" value="GIX98187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11802" checksum="D0CB26441E318423" modified="2024-11-27" version="1">MRPFNSLTSLHLRNCGFTLNSLGIPGFFEEQYITFTFIVLEKKLRESVNVILPVSEISYTETGLKIVTLATIGERFPEQHWLHVYTDGSATGADTNTGAEVYSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTJ4</accession>
    <name>A0AAV4PTJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_94881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005173">
        <property type="protein sequence ID" value="GIY00382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17877" checksum="1F3C5B741419B0E1" modified="2024-11-27" version="1">MTPEVLFEEYNLKTSDLLSSSNTESIRPWGGGEICMTPDASVYDDLALWRVSMASVYDDLAYGKVSMTILHMASVYDDLAYGKCDLHRTTILHMASRTILHSKKSMSGGLLGNSLIFQNKVSLFEIRTVTNWEGTLISKLESPSIMVEAEESNLSNSTLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3K3</accession>
    <name>A0AAV4Q3K3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tight junction protein ZO-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TJP1</name>
        <name evidence="3" type="ORF">CEXT_477701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005499">
        <property type="protein sequence ID" value="GIY02777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3K3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005923">
        <property type="term" value="C:bicellular tight junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045216">
        <property type="term" value="P:cell-cell junction organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0150105">
        <property type="term" value="P:protein localization to cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06727">
        <property type="entry name" value="PDZ1_ZO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06728">
        <property type="entry name" value="PDZ2_ZO1-like_ds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13865:SF28">
        <property type="entry name" value="POLYCHAETOID, ISOFORM O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13865">
        <property type="entry name" value="TIGHT JUNCTION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="84"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="184"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY02777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="421" mass="46361" checksum="1C42584878DD61BE" modified="2024-11-27" version="1">MEKWIGGGKTPGKICRKSFQILAARIPRNPLSFCRTRVNISVDYTPPGKTSSCIPLAEVPSCKRKISRTSFEKSAERAVWEYHTVTLSRVSGYGFGVAVSGGKDNPQFSNGDPAITISDVLKAGPAEGKLLIGDRLVSANGISLENVDYTRAVQVLRECGNSVNLVIKRKVNSTNISSNPPSVKVTLTKSKKKDSFGIVLGCRIYVKEITNQSSIEKDGTIQEGDIILKINSNSTDSMTLKEARKIIENTKEKLQLVLKRDTNQLMETNQNGQQISSNGDTKIPSPALDRADEKNNLTRLQSGRNRGPLMDISLSQLDQPATPLLTGHGHSRAPLGLDEEESLQRPPLPRIDEFTNRRDQFDDDPLARRNKTVPPEPRLYLFKRWKCGISLTGGNEVGVFVTAVQPGSPASFKDCNLEIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9F4</accession>
    <name>A0AAV4Q9F4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_372181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005918">
        <property type="protein sequence ID" value="GIY06034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9F4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10726" checksum="1CE0D3FDDF19EB7A" modified="2024-11-27" version="1">MPKIRVHRTALDEMPWTPYLMGGLRQVACPSANEGPRFSRSNAQPGDLFLEETHVPAEGGRLISSQGHKHPSFQPGKAIVFGCCNCGLKIFTNHRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAW4</accession>
    <name>A0AAV4QAW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_744181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005810">
        <property type="protein sequence ID" value="GIY05135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9343" checksum="914970D26B99F915" modified="2024-11-27" version="1">MCLLGSKFISLLGASGDVHPLHPSLSFARERGVWVTFVEDPFFSKGWFDLLENTCKRFGQRLFVQGLGSEIGMRQVWDLHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QF23</accession>
    <name>A0AAV4QF23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_721531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006004">
        <property type="protein sequence ID" value="GIY06827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QF23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8324" checksum="907F9151C5ECD5E4" modified="2024-11-27" version="1">MGRKKRINLKTIEWPRELNSRFLLIKTFNLLGQLKEFQFERVVDKRYCQGMQIRGRVTMGLMNSIAHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT42</accession>
    <name>A0AAV4QT42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_688031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006621">
        <property type="protein sequence ID" value="GIY11231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13567" checksum="23641BD92CDBBD6E" modified="2024-11-27" version="1">MQKSCKTCIAAAEKKKTWHIGKKSVHISMDIYITLFVLHGCAGVEGVQEKGLSVRILRGGWSKMKSPKPISSSFRSGEEAGFLVHDTVHQAERFRRTRPFLIGTTRSEEEWFSTRKTAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R201</accession>
    <name>A0AAV4R201_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_43501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007307">
        <property type="protein sequence ID" value="GIY15943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R201"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9363" checksum="0CCE5CBE6E7D267D" modified="2024-11-27" version="1">MVPESFAVLKKRLRKLRQNILAGDSPMNGMQMKYLMLLESVIDEEELFFTAWGFVNLNKSLILSAMGALITYGVLIVQLKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9D4</accession>
    <name>A0AAV4R9D4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_191681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007529">
        <property type="protein sequence ID" value="GIY17654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9D4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10392" checksum="3C81AB7E141C1FD7" modified="2024-11-27" version="1">MAMESLSFDVNLVIRNGGSRSVNRAELRVPALSQMDSQLKETITAVPQALIQIEPASLAEIRVINQFMRKKQFYEVHQRISSEITKIMQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBT0</accession>
    <name>A0AAV4RBT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein spaetzle 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">spz3</name>
        <name evidence="6" type="ORF">CEXT_797191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007695">
        <property type="protein sequence ID" value="GIY18925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005121">
        <property type="term" value="F:Toll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0021556">
        <property type="term" value="P:central nervous system formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032104">
        <property type="entry name" value="Spaetzle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052444">
        <property type="entry name" value="Spz/Toll_ligand-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199:SF13">
        <property type="entry name" value="PROTEIN SPAETZLE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16077">
        <property type="entry name" value="Spaetzle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Spaetzle" evidence="5">
        <location>
            <begin position="206"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY18925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="293" mass="32984" checksum="6A4B26A93993CE87" modified="2024-11-27" version="1">MQSTHSCNGVTRRGLWTVSYRHSRVKGMDPYRREKSQVLAGHTSAFVERNWNALFPFFFNNSMRGDHGTIGMSQCSLSSATLAIFALTLWLEVCAEILRGYPCIRRKNQLYCPSPGNTYPNATEGEEGRAGRERRSKRDRIEKFIDENKALVKRMVGEYSFGNEDDSNNTPAFKFDQFETYDGHPVHSRNKRARTAFGASPNKVDACESAVEIVTPYWASNSAGKIRAIVNTQHLQQAIQQEVCHNPAVFSQLFQPMFSTFYGCLGGFKIPSLIPQGWTVWGFAILFSPSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQH6</accession>
    <name>A0AAV4RQH6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_230891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008116">
        <property type="protein sequence ID" value="GIY22218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="31"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9066" checksum="184BCFC325E844FC" modified="2024-11-27" version="1">MLYLSTASVPYPEEKYLQDALMFMYDDAILSDMELRTSTKTFRVHKNILSARSPVFSAMFQADMKENAMKYVRNNRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV47</accession>
    <name>A0AAV4RV47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sideroflexin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SFXN1</name>
        <name evidence="10" type="ORF">CEXT_37431</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008419">
        <property type="protein sequence ID" value="GIY24549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140300">
        <property type="term" value="P:serine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF8">
        <property type="entry name" value="SIDEROFLEXIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY24549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="24976" checksum="742B396304513FAC" modified="2024-11-27" version="1">MTSCTYELQNFLNIEERTTPQVVFWQWINQSFNAVVNYTNRSGDSPIPVKQLGVSYALATSGALVTALGLNSLVKSAPPLIGRFVPFCAVAAANCVNIPMMRLKEIREGIPVVDKNGNRIGSSETAAKWAITQVVLSRIGMAMPGMLIPPFIMNYLDKKGVLMRYPWINAPLQVGLCGLFLIFATPLCCALFPQQSSISIQSLEPEIQEAVAKLKIEDKCLYYNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVC5</accession>
    <name>A0AAV4RVC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_769281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008445">
        <property type="protein sequence ID" value="GIY24756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="27987" checksum="5C79A017B6224FC3" modified="2024-11-27" version="1">MDINCRKLVGHQWTSIVANWLDIKCWASNVLQTGWTSMDINCRKLVGHQWTSIVANRLDIKCWASNVLQTGWESLDIKCWASNVCKLVGHQWISIVANWLGINGHQLSQTGWTSSVGHQMFCKLVGNHWTSILDINWCKLDINWCKIGHQLVQTSWTSVVQTNWTSIVQAGWYNWTSIGANWLGIIGHQLLRTGWHHWTSIVRNCRTSIVANWLASLDINCYQTGWTSIVANWLIIIGHQLLQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXW8</accession>
    <name>A0AAV4RXW8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BACK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_192662_1</name>
        <name evidence="1" type="ORF">CEXT_304781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008724">
        <property type="protein sequence ID" value="GIY26728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051308">
        <property type="term" value="P:male meiosis chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007127">
        <property type="term" value="P:meiosis I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033587">
        <property type="entry name" value="M1AP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28642">
        <property type="entry name" value="MEIOSIS 1 ARREST PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28642:SF1">
        <property type="entry name" value="MEIOSIS 1 ARREST PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15031" checksum="ACFCD4078102BE49" modified="2024-11-27" version="1">MATVAIDIFSAQFAQKFVKDVEESLTAIELAYIRQVNIEANSYQLESIFKNWLHDCGTDSDHLRLTIDKMVLRCDIKECLLNADSLPTTLSSSFSKFESPSADCKSESFIKATLHHQGSSLHHGSCLCCSKRGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2W4</accession>
    <name>A0AAV4S2W4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">A disintegrin and metalloproteinase with thrombospondin motifs adt-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">adt-1_0</name>
        <name evidence="7" type="ORF">CEXT_692861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008798">
        <property type="protein sequence ID" value="GIY27294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2W4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002870">
        <property type="entry name" value="Peptidase_M12B_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01562">
        <property type="entry name" value="Pep_M12B_propep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B propeptide" evidence="6">
        <location>
            <begin position="61"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY27294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="224" mass="25623" checksum="329727FDA534A47C" modified="2024-11-27" version="1">MRSHFQLVICEKERTMEWMVAAFFFWVLQQLAKSHPLTKPFTLKPSERWKPPIDVIYPKLHLPPHRRKRSTKADDHSLLILKTTNDTFYIKLKANDDLVEPNRLQTSSDKSTNSCHYHGTVLSHQHGSAAISVCGPKKQLSGVIVTGNNAYVLRPMDYLEKEDIPDHLRNASYSNSGAHIIMKMDNPFNEYCGGQHKDASLHFSENEISEERQGSKDPARKNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3R0</accession>
    <name>A0AAV4S3R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_610621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008860">
        <property type="protein sequence ID" value="GIY27826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="24952" checksum="ECE3653A8E34B228" modified="2024-11-27" version="1">MWSLKTVRDSRVSRRPFQVLMLQWLMSSLQAIARRMAISRATEDYCPLTVHLTHLRMCLLQLKTVTLTPLRVNRIARFMWSLKTVRDSRVSRRPFQVLMLQWLMSSLQAIARRMAISRATEDYCPLTVHLTHLRMCLLQLKTVTLTPLRNYRVKWFLWSMDMWSTNMRKDASVRHLGDVYMKNLKKWWDGYNNERFVLLSDVEPTMVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7W5</accession>
    <name>A0AAV4S7W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AT-rich interactive domain-containing protein 5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARID5B</name>
        <name evidence="6" type="ORF">CEXT_477911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009199">
        <property type="protein sequence ID" value="GIY30255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16869">
        <property type="entry name" value="ARID_ARID5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.60:FF:000015">
        <property type="entry name" value="AT-rich interactive domain-containing protein 5B"/>
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    </dbReference>
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        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051232">
        <property type="entry name" value="ARID/SWI1_ChromRemod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964:SF44">
        <property type="entry name" value="ARID DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964">
        <property type="entry name" value="RBP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="5">
        <location>
            <begin position="359"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="463"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="705"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="553"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="582"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY30255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="731" mass="83094" checksum="C8CBAB347F44A992" modified="2024-11-27" version="1">MEAKSPQFVGPPCGQYGAHTFYRGFRYAKDGRSREIGLGEFFFVRMSAEEDPCIGELQLLCSNRNNDLQLSALRLYFLPEQTPDGRLAHHGEDEILAASDRVVLKLEDLVSWITDEVEWNHGIISPSFEKLKLIAPSIVKKEEPGAPQNDDNNNDTSSAPPVVVNPENENPGEREEQNQKNEEIKDCGNKIEDLVKENKEEAATEDVKEEEKKPDEDIKEEIDQEEINPDPEDEKKTRVVVLSYQAYSRYRTILKRIENGESGEWLRDSLVQALGGAITPTSAQTRVLFCRDTFEHDELAHHELNCEYLAPNLKVKKKKKKTKTRSTSPESNASASEEIKPIIEIKDEEIKDGEKQPPIKSEQEFLQRLFKFMKKRNTPIHRVPHLGFKQIDLYLFYSFAKKLGGYDKITTKKLWKLVYDELGGNPGSTSAATCTRRHYERLLLPFERFMEGIVYKTSLRSKKAEKKEGELDQEGEKSKEEENGDGIAVKSESNHANSIEDAYEFTDSNHENSNSKDSNSNEFNSMNGDQSLANEPPFSDEDSKTVWSIQKPADNKDEASQDKDDSKPIKPLIIQKGQSESFAEKERKWDEIRKKNAAARKWVRQSRSTRGCKTPVPETPSFKNEKLTTIDGENRENCISPTTGKIKLEKVEPIPDPLNLPCTVPRNKLTPDSKINFSGNHVAKFSPPSVSPEVLNGIIKLENHTPKKRHILAKETPSRHSSDKKGHTYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9S9</accession>
    <name>A0AAV4S9S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal protein S6 kinase delta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPS6KC1</name>
        <name evidence="3" type="ORF">CEXT_502441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009219">
        <property type="protein sequence ID" value="GIY30415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06881">
        <property type="entry name" value="PX_SNX15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051866">
        <property type="entry name" value="Intracell_Sig-Traffick_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15508:SF8">
        <property type="entry name" value="LD24550P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15508">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="6"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY30415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="412" mass="47423" checksum="717BAFD0D974E1CD" modified="2024-11-27" version="1">MSKKSNDSWVRIFDVSEPILHKKGYTLYKVTSKVFPKNSIEAVTEVTVWKRYNDFKKLHKALSTLHQNLYLREPFPSFAKTRFFGRFDPDVIEERRQSALKLLQYAANCSPLFTSQVFVKFFEDGHFVENYKQTADSSKPNTDDILKPQKKFQPPDIQEPEQLEKESNVNQDERYEEPVLFLGGIWQHHQVPDAISLGSHGTDDDDDHTTFTDDDSVASRPSHSLAEFDPLFQLSNDIPGQKMTSNQENLCNSWLLSALQTCINSDSERDLENILEFPTPFGDFEISEDYIPSSGECHSGTDTNSESKESHFTFDFPTPVAEEPSDISEFDPLTHRSFSQEDDSYLYDRFAMTPNSYQKDSSRRPSYIMQSSNYVETAQKAEDNGHYEEAFELYKKAIDALILGFQKDKCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SA72</accession>
    <name>A0AAV4SA72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_599251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009114">
        <property type="protein sequence ID" value="GIY29702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SA72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9938" checksum="8A8A4E884578F886" modified="2024-11-27" version="1">MHWFNLSHVHLHFLPNTAFFFIKECLIGAANSLKTPKLNYIVVIRFVEKSETQLQYASAPVQLQYASAPVQLQYASTPVQLQYIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SB41</accession>
    <name>A0AAV4SB41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger CW-type PWWP domain protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ZCWPW1_2</name>
        <name evidence="3" type="ORF">CEXT_457211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009373">
        <property type="protein sequence ID" value="GIY31395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SB41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20145">
        <property type="entry name" value="PWWP_ZCWPW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042778">
        <property type="entry name" value="ZCWPW1/ZCWPW2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999:SF2">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY31395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="288" mass="33241" checksum="C10D950090EBB28C" modified="2024-11-27" version="1">MLTLGKCDDPAAEIADEEFLNYSPGSIVWAKLDGYPWWPAMVDENSDIEEFVWKENGITYYNVTFLDKRVTHAWILERFIRPFSNHFVGMDTFQKHKQNKYAVAIREAKQRAETALKMPIKDRLKTFSFAYLFKGHWPSADNYVVFGSLTIISMHQHYFLENDCENITDALLKEVEDLESNFSTHSDVSENEDLFIRNKETIHTSAANIENIAQEKYNTKYLNDKDFISPSKAVFPFIKSKNSFLKTETSDNQVTAENTTHSATPLKKKKVIGIKRGKNTEKPATKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SD56</accession>
    <name>A0AAV4SD56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_696951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009330">
        <property type="protein sequence ID" value="GIY31126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SD56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8107" checksum="A09C3410C5FC8A8A" modified="2024-11-27" version="1">MYIEVALTPDHITIGNSFQQLPIITFWGQFFSSKQAPSLVNPNSVARGHTHRDQAGLTASNYGVRPRYVTTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHQ9</accession>
    <name>A0AAV4SHQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Epidermal growth factor receptor substrate 15-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EPS15L1_1</name>
        <name evidence="3" type="ORF">CEXT_415681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009520">
        <property type="protein sequence ID" value="GIY32499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF176">
        <property type="entry name" value="EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="341"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY32499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="491" mass="54665" checksum="AE1C7DA9DA9CFF80" modified="2024-11-27" version="1">MISNEIKELQKEKMTLEKDLAQKEADVKIKNGELKNLQNEQDALETMLKQLEIQKGEARKRLNDLDKQFVIFLHELEKFLDLTLCDLLAQTEDDVNQIDAMKKQKEEQEMELEVQEKELSEKRKELNELRQEETKLESQISAGKTQLDALTSTLQSTILQISQMKIKIDQLQEQRRLMSEAIKDMDNAISFGDFRNVSEFTLTGFTPLKDDDFTVASPTSGLEISKDLDIYIYNFLCLLKRRIWNLLLQLVIFRKILSVAKIHLKEKLMDSVVIHLLVKILLKEILLKKVLFLQLVIPFGGDPFENVFNVTATPATQDDPFLGSDPFGGFPAPAAAVAANPEKDPFDPFGLSKSNSVQSPPLEGFDADPFGADPFGGSPAAPPRPESPTPALPPKKSKAPPPRPAPPKAKGPTIKPGPTRAAPAPPVPPPPVVDPFKADFENAATTNSAFPDLFSKTATKTQDAFDPFSNPVAPADNFANFDNFADFDNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLP1</accession>
    <name>A0AAV4SLP1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Argininosuccinate synthase</fullName>
            <ecNumber evidence="4">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ass1</name>
        <name evidence="16" type="ORF">CEXT_704601</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-citrulline + L-aspartate + ATP = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01009743">
        <property type="protein sequence ID" value="GIY34244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000053">
        <property type="term" value="P:argininosuccinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="ASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000019">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1260.10:FF:000003">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="entry name" value="Argininosuccinate synthetase, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048268">
        <property type="entry name" value="Arginosuc_syn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048267">
        <property type="entry name" value="Arginosuc_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001770">
        <property type="entry name" value="PRK00509.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587:SF2">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20979">
        <property type="entry name" value="Arginosuc_syn_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="Argininosuccinate synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0835">Urea cycle</keyword>
    <feature type="domain" description="Arginosuccinate synthase-like N-terminal" evidence="14">
        <location>
            <begin position="3"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Arginosuccinate synthase C-terminal" evidence="15">
        <location>
            <begin position="176"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY34244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="405" mass="45418" checksum="CE07D9635EDCB850" modified="2024-11-27" version="1">MEKVVLAYSGGLDTSCILVWLIEKGYDVIAFMANVGQDEDFEAAHKKATALGAKKVVIEDLRQAFVEDYIWPAVQAGAIYEDRYLLGTSLARPCIAKSLVSVAIQEKASYISHGATGKGNDQVRFELSCYALCPDLKIIAPWRLKEFYERFPGRQDLIKYAKAKNIPVPVTKSAPWSMDANLMHISYESGVLEDPWTVPPEDLYRMTKDPLKAPEEPAILDIEFKEGVPVKTTNLKDNVVKNSSLDLYLYLNEIGGLHGIGRIDIVENRFIGIKSRGVYETPGGTIIHAAHTDLEVFTMDKEIYKIKKNLSIKFSELVYNGLWFSPEGAYLQSCLQLSQKDVNGTVRVILYKGHVRILARKSPTTSYNQELASMDFPGDYAPDDAEGFIKVHALRLKEHFRAKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVK7</accession>
    <name>A0AAV4SVK7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_491351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010219">
        <property type="protein sequence ID" value="GIY37810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9999" checksum="104132BA3F97FACA" modified="2024-11-27" version="1">MGMGMFNDLEYRWSMGMFNDFGVWRCLRIVEHCRNEISKEKKTNGLSSNSVAYLVPSDPSKRLVFRMAGHLFLPSFQKTRVNDFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5F6</accession>
    <name>A0AAV4T5F6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Obscurin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Unc-89_9</name>
        <name evidence="2" type="ORF">CEXT_181301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010708">
        <property type="protein sequence ID" value="GIY41350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5F6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11161" checksum="F5119C6329900B10" modified="2024-11-27" version="1" fragment="single">YHNKFADAGERRDCPRSLGPHLKPEGAPKVKVSPRRKYQQEFTERTPDYQLEEFEIPILDYSRETEPVPLVESDPLELGSDRSLEMARQRHLRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGU7</accession>
    <name>A0AAV4TGU7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein asunder</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cell cycle regulator Mat89Bb</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Set apart in position or space protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">INTS13</name>
        <name evidence="17" type="ORF">CEXT_128991</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="16">Belongs to the multiprotein complex Integrator, at least composed of IntS1, IntS2, IntS3, IntS4, omd/IntS5, IntS6, defl/IntS7, IntS8, IntS9, IntS10, IntS11, IntS12, asun/IntS13, IntS14 and IntS15. The core complex associates with protein phosphatase 2A subunits mts/PP2A and Pp2A-29B, to form the Integrator-PP2A (INTAC) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Perinuclear region</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the Integrator subunit 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011217">
        <property type="protein sequence ID" value="GIY44954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051642">
        <property type="term" value="P:centrosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019355">
        <property type="entry name" value="Cell_cycle_regulator_Mat89Bb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12955:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12955">
        <property type="entry name" value="SARCOMA ANTIGEN NY-SAR-95-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10221">
        <property type="entry name" value="Mat89Bb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0221">Differentiation</keyword>
    <keyword evidence="11" id="KW-0469">Meiosis</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0744">Spermatogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00061603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00065185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY44954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="690" mass="77022" checksum="2BFD482DF798491E" modified="2024-11-27" version="1">MTFPVSHKTIFVLDHGPNFLGSCQQNMEFDIFTKTRQPGIIPLAPLSKSLWTCSVEAAIEYCRIVWDIFPTEKLIRFIVSDNTSRTLNSWSQDQQNLSHLMAALAQVGPPENISITDCNVMHGLNAAIEALCECSEIQHEKRTSLTDNAGKVINRGRIICFTNVKSDLEVNSIIDCFQNALSEHNKLASGSDSLMTIQHCELILMHVHPVNKESCITPQTRKAVSTVLSTEIHNIKSGRHLATKLGILVQQHYNLASTTVTGIPMKEEQNASSSANYDVELLHPVAAHAEVFKTGVVNAEGVHITTVKEGQLYETVTLKWCTPRSSSVELQYCTSSFRITPVDVNNRPSSCLTNFLLNGRAVMLEMPRKSGSKVLSHMLASHGGEIFIHTLGTGRSILEDPPSISEGCGGRVTDYRINDFGDFMKQNRLVPHNPRIERIEMPIEAEKKLTRLTQYWPLVFSHTTIFNNASQISSLLQLITKESLDANDVNDCKKSIFNLVSSENKGLPLNVPTISTRGKGPKREEHYRIAWNELEAFVRCHCTTAEHQSVLECLLECRKPNADGENNASIASVKLQLGALSPSHSPIKKEKSFKDEKDFTKLYDSDDIKEISRKQSFDSIGDSSFNKFRPVKKLKLSREVIKSSGNKSLLSLWTDRLNAETEKRFVEFAGRVNGNGPAKLYTNLKNEPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIS4</accession>
    <name>A0AAV4TIS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_767411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011047">
        <property type="protein sequence ID" value="GIY43878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9453" checksum="A8E54F59C9E4E843" modified="2024-11-27" version="1">MKSNLVSPLHYQDKINAKYTCGGNKSQKDAQENHSGAHYRMNDEKPLCAPLRRRLERTPPAICVNYQEHAEDRRMANILEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRR4</accession>
    <name>A0AAV4TRR4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_25681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011770">
        <property type="protein sequence ID" value="GIY48880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="29"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY48880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18333" checksum="01540CEB5F3E9EF8" modified="2024-11-27" version="1">MLNHIWLSGCFDNHCQFIFKSITLEAGREATKLPVLVFIHGESYDWNAGNPYDGSILASLGNVVVVTVNYRLGILGPDSELHIFNHTVDLSICYDKRKVALNFSKRERHVGLPNLKKLCLKPSKSCVHGKANFLGRKVLPLTQGGGKRYTNHPDIPLRSHSILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRS4</accession>
    <name>A0AAV4TRS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_496441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011666">
        <property type="protein sequence ID" value="GIY48022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15533" checksum="E49F468CD1309DF9" modified="2024-11-27" version="1">MNPEDETSVEILFLCILSFVMKPQTKMRLFATNNFLETSEDGTFVTQSLLKHKIVCRELDASGSFPSISIYPGDFKKDHFKHEISLGIEEKSVCVVRFFRAKGCIGYGLAKGEPEKIYRDVPICRGNISFSWREKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TU08</accession>
    <name>A0AAV4TU08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_785871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011823">
        <property type="protein sequence ID" value="GIY49364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TU08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10891" checksum="E611DB2A92CFF7DC" modified="2024-11-27" version="1">MALVALNTNQPTNQPILPESVISWFSPRIIHFGLSAFFSLVTMELGQSCQALKALLQWFKTRGRVSLCSGQRRHLLSFPVFHCWAPLRGIRLRLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TXA5</accession>
    <name>A0AAV4TXA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_508341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011856">
        <property type="protein sequence ID" value="GIY49610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TXA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8134" checksum="03CD398EF43BDBD6" modified="2024-11-27" version="1">MLSLHLLDNACRFNKTEHPHISDSIRHYLSLVFRDGRDPLIIYQTRSRNSLLMFKSLVHENPAIPDENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1S9</accession>
    <name>A0AAV4U1S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_476031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012146">
        <property type="protein sequence ID" value="GIY51705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13362" checksum="2D3132E82AA81FBB" modified="2024-11-27" version="1">MKSGLVNTVEGIRGYRTFIIGRRHWDGKKNVMVNPSEEPDHLFDIHRLRGMNNKCAQIWDYTINLEFPKQLCLENPLRLQRMNVTKYSVAKDAETFTPRNFEPSIVPKTRLVGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2G8</accession>
    <name>A0AAV4U2G8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_65243_1</name>
        <name evidence="1" type="ORF">CEXT_373681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012177">
        <property type="protein sequence ID" value="GIY51946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2G8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9719" checksum="405B6F7250ED70CB" modified="2024-11-27" version="1">MTAASTAASSLPPVRTSCHVPLSLMTSISEETIALWLKLGALEKLEQAVLDGYGDQLCGKPQEFHKSTNFLNKCHFFQVKSFLKSCSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9N9</accession>
    <name>A0AAV4U9N9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_31203_1</name>
        <name evidence="2" type="ORF">CEXT_230471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012515">
        <property type="protein sequence ID" value="GIY54468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9N9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="22610" checksum="2F7D1BA56AED2EBE" modified="2024-11-27" version="1">MSFRNLNGVLERIPRDSPAKGTRDILIGRLNWQHNLTRDGRKEEDDGPPMSHRNFPPSFWNSNYQPMPNSNLGPMGPGSLGSLGPELAPFASSYHPGSARFASQYGSLLLQPAVRSPGRLGPAAAACASLEKADSWAASRYHDSLGHVDSNYGAAYGAMTPMTANPSGTSLNCTIELYPEISMVHTECTIPMESDVQSKCPQFETIAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UGC9</accession>
    <name>A0AAV4UGC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_656491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012820">
        <property type="protein sequence ID" value="GIY56868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UGC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10502" checksum="119925D6C4A53560" modified="2024-11-27" version="1">MAHKVTAPNFHNCPSHNNSKKKKKKFQREKEFLPAGSGWKIVKLHAFLLGGGHHCSCPSRFPINDAVKLRRREQEWGNWQLAGTPISDAGDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHR3</accession>
    <name>A0AAV4UHR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_766711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012891">
        <property type="protein sequence ID" value="GIY57348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9268" checksum="6547C206BE6EFE7B" modified="2024-11-27" version="1">MRSEQAARPDLSDLLRQSGERFDNATTLGPKRLPSVTSGEKSSHTNITPASLKIMRSEQAARPDLSDLLRQSGKRFDNTTTLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNN9</accession>
    <name>A0AAV4UNN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_635041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013209">
        <property type="protein sequence ID" value="GIY59470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11857" checksum="33C9A3CEAB24E03C" modified="2024-11-27" version="1">MIICEAVSAADSRVELPLSEHVKVTPPFRYPCWFSPSFLDVRAPTLVYCQSKAARKYLCSKNCLLGFHTIVVQLLKVNRKCHNSMHVCCSSGKKYPLNMLIYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWU9</accession>
    <name>A0AAV4UWU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_84411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013595">
        <property type="protein sequence ID" value="GIY62221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11091" checksum="0528A5818B8F7726" modified="2024-11-27" version="1">MQLVQSDALLFLSASLSPSIRNTLPSGSRQIVVTVLCQLEGRLEDVTSLAYDIPVETEIWLYDSHVMASLCLWFYDNEINDWLKYTIFPYNSEHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V218</accession>
    <name>A0AAV4V218_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase CEXT_613081</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Eef1akmt2</name>
        <name evidence="7" type="ORF">CEXT_613081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01013838">
        <property type="protein sequence ID" value="GIY64167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V218"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03188">
        <property type="entry name" value="Methyltr_EFM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026635">
        <property type="entry name" value="Efm4/METTL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843:SF5">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="58"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY64167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24329" checksum="54ABDB3A58BB6094" modified="2024-11-27" version="1">MEELSPSSTCELGRREYWSEFYSEELENFEDHGDTGDIWFGKKNVERIVSWLTNKELEKNLPILDVGCGNGMTLVFLAKAGFVDLTGVDYAEEAILLAEKIAQNKNVMNFLEEDSRNFCSKEFSIIIDKGTYDAICLDVKHVEEKRKQYIYQILSLLASDGYFLLFSCNWTKEELLIHFKDFALYDEIEIPSIGFGGKTGQTVTALVMKRAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAR7</accession>
    <name>A0AAV4VAR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_521801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014183">
        <property type="protein sequence ID" value="GIY66989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11090" checksum="F3D11443C168E036" modified="2024-11-27" version="1">MEKFFQDSSLTAEEECTMTVDQEKVFPALDYLEQCASVRFSFRLLYKKLIYKSDPNHPHIHMANNNKGKKSASPAAKFTEEENGASGVLGRKFARQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLG7</accession>
    <name>A0AAV4VLG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_299051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014741">
        <property type="protein sequence ID" value="GIY71006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10899" checksum="26A781F6DDB7B7EC" modified="2024-11-27" version="1">MTYVYIDANVSSESSDNEDTDISFLMTDENLEQDMSDLLYHDVTFRSTLNRKSGIVVGRSYSLWSLSLYPKRLSKMADSQLLSPSFCSTKHGSEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VQA2</accession>
    <name>A0AAV4VQA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_786071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014937">
        <property type="protein sequence ID" value="GIY72371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VQA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY72371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8645" checksum="9FC71E5D5F66243B" modified="2024-11-27" version="1">MNEKKIPNFPKLPTPVDADSDNEKLFRNKGSGILRPAGNCEGKQRGQTALQHYYALKRVREGNRRVFNFLQKRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRU8</accession>
    <name>A0AAV4VRU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Amiloride-sensitive sodium channel subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">scnn1b</name>
        <name evidence="13" type="ORF">CEXT_96541</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014977">
        <property type="protein sequence ID" value="GIY72669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY72669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="233" mass="26703" checksum="CD1915E9CF3BD311" modified="2024-11-27" version="1">MKTIPTASVHRFLQKFHQESQRCELIRIPSTPYSNETCLCEGTSTQDSWGGSFPEEDIQGLLDSIPEENVKNVIQIIKRSKTYDLVDVEEALMPSIYELYNYGVTFDSLVTSNFTVLYHPNYGKCYMFNYVGNEHSEVEEPIEIDRYGSTSGLQLLLRVSDSDAFDLLRREVGARIVIHDPHMLPFVAEYGVNVEATGHDCCRVIPVQDTQIGETMGQLRRRGHRRRRWTPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTE6</accession>
    <name>A0AAV4VTE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_96421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015049">
        <property type="protein sequence ID" value="GIY73224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14240" checksum="C60D90D8985D7666" modified="2024-11-27" version="1">MVITWKGQAGFAIINSKVHLHAPEIPAYVIYDWTEQEGSQKLEVEQHKGVSIPCTPFRNLASDDRTVKVEAGKMIHTKYFNGRKFSQKEKNAEIGKCPKRRHFRNFEHKEIYILGGDRALETIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWF7</accession>
    <name>A0AAV4VWF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_233741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015246">
        <property type="protein sequence ID" value="GIY74702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13651" checksum="93EEC4C8D302C92A" modified="2024-11-27" version="1">MKLLIIHNYELINHDVNHEIILGTTSTAQLYVDDVQWPFATTHGKAEPLQSYVNSNKDGNFIKDGPSELPLCCGYSSFGNKVSRTFCNYKCRTHDRPLNLDSVNFYISGATVEEFWLFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VYL5</accession>
    <name>A0AAV4VYL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenosylhomocysteinase-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AhcyL1</name>
        <name evidence="6" type="ORF">CEXT_698371</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015362">
        <property type="protein sequence ID" value="GIY75561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VYL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033353">
        <property type="term" value="P:S-adenosylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1480:FF:000007">
        <property type="entry name" value="Adenosylhomocysteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S-adenosyl-L-homocysteine hydrolase NAD binding" evidence="5">
        <location>
            <begin position="69"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY75561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="273" mass="29873" checksum="9A9FBE0D67FC895E" modified="2024-11-27" version="1">MVVEVILDDGGDATHLMLKKYPAMFRGIKGIVEESVTGVHRLYQLSKAQKLTVPAMNVNDSVTKTKFDNLYSCRESILDALKRATDVMFGGKHVLVCGYGEVGKGCCSALKGMGAVVCVRNRPYLCFLQACMDGFRVVKVNEVVRNIDILVTATGNKNVVTREHMDKMKNGCILCNMGHSNTEIDVQSLRGLTLGESRLANLSCSTIPSFVVSITASTQALALIELFSAPADEYVASLHLPTFDAHLTEMTEGSEARYMGLNRAGPFKQAYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WE51</accession>
    <name>A0AAV4WE51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_671971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016033">
        <property type="protein sequence ID" value="GIY80648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WE51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="8654" checksum="6B8F1E379E45C008" modified="2024-11-27" version="1">MCALKEAKGRGISLASVFSGGVQASRRPPVDYGGCRGEGQRGMEAKGRRISLASVFSGESKRRDDPLDYGGCGGGSRGWSVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJX3</accession>
    <name>A0AAV4WJX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_696131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016156">
        <property type="protein sequence ID" value="GIY81690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11340" checksum="4819006DAF8F0AB2" modified="2024-11-27" version="1">MTQDVSEITAQVSVQLKESYNTMMSGTRLGRSIFKGVVSGLMEKKSTMCVQSDCISGQAVKWWFQALRSLHSSIQRSLEMLVWFGQSSLLNSPGKIPLSTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQ01</accession>
    <name>A0AAV4WQ01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_20681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016603">
        <property type="protein sequence ID" value="GIY85000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQ01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9103" checksum="94B61CABE7DD9E89" modified="2024-11-27" version="1">MTKAEDRVKRTAGEIGLIMENSEQMCHPDLQSKQLASGKLKWFLLSGGPVSGTDLEKGSYILLNPQKTLGVGDMTVLFKGGGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7L8</accession>
    <name>A0AAV4X7L8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_114651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017266">
        <property type="protein sequence ID" value="GIY89849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15511" checksum="3D8B2F87A89F0707" modified="2024-11-27" version="1">MQWCRDWLSTFECTLVCYVQQGQSDHKRRAVFFGLQLEHSFLVDFAYRHICLYILESFYLLSCCFVFTLLPRRLVSGILQFTHQKACRSSSMATKGLNDFENSLKVASDVSNSKEFISGPSSQCRNMGCGAAHDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7U4</accession>
    <name>A0AAV4X7U4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_114601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017266">
        <property type="protein sequence ID" value="GIY89839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12431" checksum="692310EA69B30AFD" modified="2024-11-27" version="1">MKTAVLRSATGPALEKVTGWYWNLGFEKMNADCQVRFRKPHDVALLSADKAGLWSLSYGEEPKRVARKACWAPACLATSQASLAFVIQPALSHFSFLLSRDRIKTSIKSFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFY9</accession>
    <name>A0AAV4XFY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_172681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000336">
        <property type="protein sequence ID" value="GIY94002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21013" checksum="39A2C1FC91B15314" modified="2024-11-27" version="1">MPISLPPVARQSVLRSLIRNSASSHSKGCFSEDFHCVLVSVPFDAANSSHWHAFLWTLVGHRGRQQVHRNIRRHQPPRGRAAGGNPVPDQTQAVFHGEGPAQEGVREPGRGRGQAARGQVPGVRRVQGQRNSQEDSEESVLQIQVMRQPPCSLRQQFQLQIVCNSNVQDVHMNQNWIAHTTIGIYFHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIV7</accession>
    <name>A0AAV4XIV7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Neurogenic locus notch homolog protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NOTCH2</name>
        <name evidence="9" type="ORF">CEXT_608921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000324">
        <property type="protein sequence ID" value="GIY93901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0048568">
        <property type="term" value="P:embryonic organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010160">
        <property type="term" value="P:formation of animal organ boundary"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0042063">
        <property type="term" value="P:gliogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022407">
        <property type="term" value="P:regulation of cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007548">
        <property type="term" value="P:sex differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="7"/>
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    <dbReference type="FunFam" id="2.10.25.10:FF:000230">
        <property type="entry name" value="Delta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000080">
        <property type="entry name" value="Neurogenic locus notch 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Neurogenic locus notch 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000279">
        <property type="entry name" value="Neurogenic locus notch 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000060">
        <property type="entry name" value="Neurogenic locus notch protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Neurogenic locus notch protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000125">
        <property type="entry name" value="Neurogenic locus notch protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000063">
        <property type="entry name" value="Slit guidance ligand 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Laminin"/>
        <property type="match status" value="10"/>
    </dbReference>
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        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
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        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051355">
        <property type="entry name" value="Notch/Slit_guidance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45836:SF23">
        <property type="entry name" value="NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45836">
        <property type="entry name" value="SLIT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
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        <property type="match status" value="5"/>
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    <dbReference type="Pfam" id="PF07645">
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12661">
        <property type="entry name" value="hEGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00010">
        <property type="entry name" value="EGFBLOOD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
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        <property type="match status" value="9"/>
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        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="8"/>
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        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 7" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="16"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="63"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="101"/>
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        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
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            <begin position="139"/>
            <end position="174"/>
        </location>
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        </location>
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    <feature type="domain" description="EGF-like" evidence="8">
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    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
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            <begin position="322"/>
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        </location>
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    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="362"/>
            <end position="399"/>
        </location>
    </feature>
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        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
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        <location>
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        </location>
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    </feature>
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        <location>
            <begin position="389"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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            <dbReference type="ARBA" id="ARBA00023157"/>
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            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY93901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="430" mass="45870" checksum="512B1A9D66E846F3" modified="2024-11-27" version="1">MMCVPYVGVYQKIAQMADNVQKKRHSICQNGGTCNVGLSPKNASTFTCSCPVGYSASLCEIAVPNSCDSNPCQNGGICNLVTLDNYTCSCTVGYRGRHCEELDHCSTRPCRNGATCLSRQDNYKCTCTEGFSGPTCTTDIDECGRDPCIHGRCVNTVGSYRCTCETGYTGQNCESQYIPCEPSPCENGGTCKALDALSYKCSCPEGFTGTNCEVNIDDCPGNICQNGAKCIDGINSYTCQCPPTYTGSYCSKDVDECSVRPSVCKNGATCINTIGGYSCICVNGWSGEDCSENIDDCAGAACFNGATCHDRVGSFYWLLCHLEDACASNPCHVGAICDTSPIDGTYICSCPSGFKGVDCTQDVDECEEGSPCEHGGTCVNTPGSFHCNCTKGFTGPRCEININECDSNPCKNEGTCLDEREDFVVCLHAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKW4</accession>
    <name>A0AAV4XKW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">E3 ubiquitin-protein ligase TRIM33</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TRIM33</name>
        <name evidence="2" type="ORF">CEXT_157101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017961">
        <property type="protein sequence ID" value="GIY95782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="152"/>
        </location>
    </feature>
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            <end position="250"/>
        </location>
    </feature>
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        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="426" mass="47926" checksum="8809934081A0E303" modified="2024-11-27" version="1">MLPMPRALSQSPILSNPAPVIRQPPPMQMNQQRMVQQMNQLPVQQMNQSAMVPYGQPQVTSSTDLNQRNQQMRQLNKQVAYNRNMQRNVQQSPQAAYNMQGNNTSMLPNQMLQHNPQQVRQPVQVQRQQIQHHQQQQQQHHHQQQQQQHHQQQQQQQQQQQQQQQQQQQQQQQVQQVNYNNTQQLPIQALRQNKSISVTAVPASPTGTPNKQRVIAPRNLNMSVVNNQSPSVQRNNSNPSTPQRSSGPQVIVLDDAKTTPTMSNTNRLSHFPNIAATLASHPGLQIQPAGFNNSSVQNQIQLVNLQSGSQVKILPTPPNPAPVCTVVAPIVTQNNPVNQIISGKTPMILLKPIAFSENPSRVETTDSSLSTAEESALSDNGNRQRNMVSMLKGDNTRAEMVTDNPVHMKAHHLNQCHQLGSSPHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMJ8</accession>
    <name>A0AAV4XMJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_538011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000485">
        <property type="protein sequence ID" value="GIY95160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14022" checksum="B05F6BDECCFF2F98" modified="2024-11-27" version="1">MIKRGKTNREEEERPRKKNEEEEEKEVNHSGRGCKKKNWAVSMDTSQRRENSHRGLVQRHNAEKKASKLSASVNPLFYKKQVSEADASRTKSEDLPHPSTPLTRIPTLYHKAHSFLLQSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNY0</accession>
    <name>A0AAV4XNY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_301371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000691">
        <property type="protein sequence ID" value="GIY96701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8930" checksum="9D21029203BCC6F3" modified="2024-11-27" version="1">MSSYKEHLDLKGLDDEDDLSDDEVFTQGGKSIPLEENGAYVVSYLLFASDIIINNYSYWHSSFTHQYFYEEYFIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP68</accession>
    <name>A0AAV4XP68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_158981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018093">
        <property type="protein sequence ID" value="GIY96821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13243" checksum="1E243679FE62DD0A" modified="2024-11-27" version="1">MGRDNTIMLYPKLLLRLPDLRELNDYPLLDYNLRLGTGSATDSTETVFAEDRFMFSRSEKTSVVLAIQKGTTDPWIRVGLQTSSEVSSARVPWSLVRDVLRLQHRLFLRRRVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSD5</accession>
    <name>A0AAV4XSD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NECAP-like protein CG9132</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CG9132</name>
        <name evidence="3" type="ORF">CEXT_174451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NECAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018142">
        <property type="protein sequence ID" value="GIY97268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13228">
        <property type="entry name" value="PHear_NECAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="2">
        <location>
            <begin position="43"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14195" checksum="CACDAFF854841B48" modified="2024-11-27" version="1">MEEYETVILVKQEVFVFQIPPRATNRGYRAADWKLHSPDWTDECELELFAKAPIDKYPGIAIESVMDSSRYFVLRIEDDNGRAAFIGIGFADRGDSFDLNVSLQEHFKWLQTSEEIEKGTKCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTC8</accession>
    <name>A0AAV4XTC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_170801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018280">
        <property type="protein sequence ID" value="GIY98292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11565" checksum="68BDCB00FCCE537B" modified="2024-11-27" version="1">MRIAAIKFPNEVFLNCEYLRRYDVRGEYFNFKSILKSPSYEHLLMRIAASKLPFLPKRGVPQSHCISSVYLNIEDTMIEVNIFLILNPFLKVHHMSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTL7</accession>
    <name>A0AAV4XTL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_7681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000758">
        <property type="protein sequence ID" value="GIY97260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24401" checksum="785E72D16D0F7C2B" modified="2024-11-27" version="1">MISGSICSKLPAVIIWYTARVLSRCMQSLDFSSISDRFMVSPFSEYPSNPKQFSVALFHFATESPVTPLLVLGIWRATVQIYCSWTVLRNEGRRVDFECDWKESGPLMPWQKESFGTGFVSKWVNHGPENARFAQRQIQITNPWSSGARQGFRHKPLDPEYPSNPKQFSVALFHFGPRNLSSDSLLVLGIWRATVRIYCSWTVLRERGKRAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU35</accession>
    <name>A0AAV4XU35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_497641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000788">
        <property type="protein sequence ID" value="GIY97501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7756" checksum="0C01274BD9452B13" modified="2024-11-27" version="1">MEIVMTCSNVSEAKWPGGEPLIQHSQRGAVVCNFKRKDFIAQAARGSRDAWHGCEQAGTQPTVDSGLTAPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0K7</accession>
    <name>A0AAV4Y0K7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_285571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018569">
        <property type="protein sequence ID" value="GIZ00623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17084" checksum="E1F4DBB793EBB5D6" modified="2024-11-27" version="1">MVSNVYFRTVKSVESYFTSFINYAEKFTQKVDSAGPPEVKRVCHEGNGLNIKTVEETTLKESHLWKVNLGVPKSRVRKRIRYGIRGERGRPLHHQTDSVKDINSPFAPLSLMKEVNKPIFCRRLPELIALFFSFGPRIVEFAVFGRVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6U8</accession>
    <name>A0AAV4Y6U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_744291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001547">
        <property type="protein sequence ID" value="GIZ03073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9800" checksum="DBF84DF9668AF278" modified="2024-11-27" version="1">MIFDSFFNDDGHDGDDVHGDDRDVHGGHDDDRDAHGDDGHDGDHGDGHGDDHDVRDDHDDGRGGRDDHDDDVSLYSIWSGFAGNTLEGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y738</accession>
    <name>A0AAV4Y738_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_717281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001510">
        <property type="protein sequence ID" value="GIZ02820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y738"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10526" checksum="4F0A9A290E6BD511" modified="2024-11-27" version="1">MKISNARHSREEGRKIITGGRQQSQNSHEDLIKILYFSLAEWKRNKFSPFLKFPPGLCPQEVEMQNLISGPLSCHGFRNAIFSRALSIPIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9Z7</accession>
    <name>A0AAV4Y9Z7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_631341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001685">
        <property type="protein sequence ID" value="GIZ04047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9Z7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11149" checksum="A1C25CB2A58A61DC" modified="2024-11-27" version="1">MYTRVSANLHGSGILDLLTKRDKKINNCGLGASQHQHQSAVVSRLPRGCRAWRGCISSSKGSPPSPSWRFSKTKLLTCSPITGHWDVTHRIQTRPSKQGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB34</accession>
    <name>A0AAV4YB34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_13651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001692">
        <property type="protein sequence ID" value="GIZ04144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15004" checksum="A87DBC02FC4AFE0A" modified="2024-11-27" version="1">MLSVDRTGRPAARPADPQAPVFDSLVDGMEHGTEVGPGLFRDGRTAIFGPLSDLAHRRYCCRAAATGPVTSRGPGTHTHPAFLAVEGVGRKGTCAEGDGIVAMATLVNIRAPFFSLSRFFPDHPRFVSARAVVLIVEARFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBV6</accession>
    <name>A0AAV4YBV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_369031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001785">
        <property type="protein sequence ID" value="GIZ04722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17461" checksum="E56EE31EA63F838E" modified="2024-11-27" version="1" fragment="single">GCIILLIFQSTEVNMGIFRYDLHSRSMNSRKSISEVASFFLSFNPTEVNMGIFGTTRILGYELQEDHLRGCIILLIFQSNGSKYGNFRYDSHSRTGQGRSCDSKIGGRFRRDSSNFPVNSGEKGQICIGSHPLTLASKKKVGKKTISLYLPIISMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YC02</accession>
    <name>A0AAV4YC02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ubiquitin-conjugating enzyme E2 Q1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UBE2Q1</name>
        <name evidence="9" type="ORF">CEXT_245461</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019012">
        <property type="protein sequence ID" value="GIZ03911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YC02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23802">
        <property type="entry name" value="UBCc_UBE2Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000006">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 Q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="192"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIZ03911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="41826" checksum="8B18CE7DD0387293" modified="2024-11-27" version="1">MACLNNLKQDIKTLETLFPKGHELFQITAASVDELTCRFICHNGKKFEIHANLTETYPSTPPVWFAETEDPCITNAVQILTNTSGRDNLVLQQVKLLIRELCRLHNVQEPIELNHLQSTTVAPVCISEEELESNSEEEDEAEDDIHIEMEEDTSPDKSKDEGISSEHTATLERLRQNQRQDYLRGSVSGSVQATDRLMKELREVYRSESFKKGVFTVELVNDSLYEWNVKLLKVDPDSPLHNDLTLLKDKEGKDCILLNLLFKEAYPFEPPFIRVVHPMITGGYVLGGGAICMELLTNSNEILFQQGWSSAYTVEAIILQIAATLVKGKARIQFGGNKSQYSLARAQQSFKSLVQIHEKNGWFTPPKEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCT0</accession>
    <name>A0AAV4YCT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_803691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019172">
        <property type="protein sequence ID" value="GIZ04953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10495" checksum="295F3CEFE21067F1" modified="2024-11-27" version="1">MTLLAEDQSDGGGGREKDRLRWNDNSESDFTDRFRDRCCRNKNLRSCGELRNVVFAWVAVDIGCCNHSLDTYLVVGIECLDTLFNEKGTRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M552</accession>
    <name>A0AAV4M552_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Catalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cat</name>
        <name evidence="10" type="ORF">CEXT_224501</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001858">
        <property type="protein sequence ID" value="GIX67206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M552"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000001">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX67206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="472" mass="54446" checksum="C00D08A4AB66894F" modified="2024-11-27" version="1">MQSTLMKWLTSTEKRIPERVVHAKGAGAFGYFEVTKDITRYCKANLFSEIGKKTPIAVRFSFVSGESGAADSTRDPRGFAVKFYTEEGNWDLTGNNTPIFFIRDPILFPSFIHSQKRNPVTHLKDADMFWDFLSLRPETTFQVTWLFADRGIPYGYRYMNGYGSHTFKLVNNENEAVYCKFHYKSNQGMKNLTSEEARALAGTDPDYAIRDLYNAIARNEYPSWTLFIQVMTFEQARTWRFNPFDLTKVWPTNEFPLMEVGRFVLNRNPNNYFAEVEQLAFAPSHMVPGIEPSPDKCCRFTDLSQMLEISLYIAGQAVLVCRYPQISFGCQFFCRSPSTVHIAPPREIMKGWPSNSQRNQDGAPNYYPNSFNGPVVDPAVREPPFQVSGDVDRWNSEDEDNFTQAGIFYREKLADDEKERLVKNIAEHLINAQEFIQERAVNNFTQADVDYGKRVKAELEKLKAHRNRTDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M767</accession>
    <name>A0AAV4M767_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_327801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001813">
        <property type="protein sequence ID" value="GIX66689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M767"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11365" checksum="7BB47FE21F90E07D" modified="2024-11-27" version="1">MYILPPFSLLAGYSFQNPPTDLYVFPLVGRERISTLNQFERAAIPLWSSGVISPEQEAFTKTSVKTWLIIQSPPKSLYFFSVKPPLRINKRPHVIPQSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8S7</accession>
    <name>A0AAV4M8S7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001997">
        <property type="protein sequence ID" value="GIX68769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8S7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="16283" checksum="CA02C8384EE86481" modified="2024-11-27" version="1">MPKETADHLLLITRSRTTIWGPWKTRRSEEQAVTQGLMEAAGPFRVVIYLCDGRLGRRGQLRTYVMMQRKEKRCKQSRTTIWGPWKTRRSEEQAVTQGVMEAAGPFRVVISLCGRRLRRRSQLRTYVMMQRKEKRANSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAJ8</accession>
    <name>A0AAV4MAJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_42481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019529">
        <property type="protein sequence ID" value="GIX68865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00636">
        <property type="entry name" value="TroA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10522" checksum="9D64D66F7D8D746E" modified="2024-11-27" version="1">MDDKNGTAQGRRGNYIQETGLTGKGAGRKESEWSVRNTEFIAQKQKIAISSVNCDNGERFTAEEVKELLRKEEEAQEILEGIRLEAIRKRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MC37</accession>
    <name>A0AAV4MC37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_809631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019630">
        <property type="protein sequence ID" value="GIX69908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MC37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12885" checksum="5AA7D3F3C71DE4E7" modified="2024-11-27" version="1">MTWAFNGTRFKLYPCGQRHLRQSSISNKGSIPHWFLLCPEEEISKNDSRDMAASIVSFDIIFSIRQVYVLQSSGQNEPARVSSHVDTPHFPSKRNQLLFSASNGGATLVTIPALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MH48</accession>
    <name>A0AAV4MH48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_649831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019776">
        <property type="protein sequence ID" value="GIX71663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MH48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7979" checksum="7492044DD1A21D28" modified="2024-11-27" version="1" fragment="single">CIPSSFPSRISESLTGCLFHATKSNQVHLSHLTQPDSPLSLTQPLTEPGFNCSQEAVGRIELPSYDWILPPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKN7</accession>
    <name>A0AAV4MKN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_90631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019819">
        <property type="protein sequence ID" value="GIX72117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17921" checksum="408C3B94CE9C528F" modified="2024-11-27" version="1">MNVLSTHQEILSKPSTSDYEKSVTDIIDKIIPNKNLHMRAWKNLMQDLIAEERNMLSTHQEISSKPSTSDHKKSATDINNKNIPIKNLNLRTWKNFMQDLFAGERNMLSTHQEISSRLSTSDYEKSVTEIIDENIPNKNLHLRAWKKFDTRPIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMN4</accession>
    <name>A0AAV4MMN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_674861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002431">
        <property type="protein sequence ID" value="GIX73598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="362" mass="38742" checksum="5B63BA198C91AD71" modified="2024-11-27" version="1">MISSRRDKRPFSKLRRAKRPPERSAIVETNLNKRRRSPLPVLVSESRPLTEPAAEIDAGAVQAAMSRVINKSLRKAILKIAKSPASTGCALPQSAIVKTNSTSVVIRCGSKSRPLTEQPAAEIDTGAVRCLSSLTSLCGREKFSAIFKIAKSQPEFEPEGAPLHSAIVETNSTSVAGACVRSKCWPSTQPAAEIDSGAAMSPPSLTSLCGRERFSTGRFQIAKSQASIGAFPPFSQNELKQGVVGAPLPVSVGKEPASDSASCGDGYRCCAGGHVTSLTSLCGRPFSKCRRAKRQPERALPISAIVKNELNKRRRSPFRFEREKSRPLTEPDAEIDTGAVLAAMSGVINKSLRKGRGFSVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNU5</accession>
    <name>A0AAV4MNU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_389431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019957">
        <property type="protein sequence ID" value="GIX73505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12143" checksum="E72E94226D801720" modified="2024-11-27" version="1">MCSRKITRKLVENYMPIAQSPYCNCFVKIKIKQPQVASTTESDITLFMRSCKSFQDYGKERSTRHSSSNVQIKCSFAMIAHLQLISPFLMLQLSQVPRKNEQSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPT4</accession>
    <name>A0AAV4MPT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Molybdenum cofactor biosynthesis protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">Mocs1</name>
        <name evidence="17" type="ORF">CEXT_252791</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MoaC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020076">
        <property type="protein sequence ID" value="GIX74557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040064">
        <property type="entry name" value="MoaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047594">
        <property type="entry name" value="MoaC_bact/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006870">
        <property type="entry name" value="PRK09364.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01383">
        <property type="entry name" value="cyclic_pyranopterin_phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01386">
        <property type="entry name" value="main_SPASM_domain-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01067">
        <property type="entry name" value="SPASM/twitch_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="37"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIX74557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="530" mass="59143" checksum="3BED67985FB9D97A" modified="2024-11-27" version="1">MKHIKLFVNQFIKSARRFNSNFLNIKDGDLSSYLVDTFGRKHDYLRISLTERCNFRCQYCMPEEGVSLTPKKHLLTTNEVISLASLFVKLGVTKIRFTGGEPLIRKDLVDIIRATSELNNLQTVAMTTNGFVLHRCIEELKNAGLNALNISLDSLIPVKFEFITRHKGLSNVMKSINATLELNFNPVKINCVVMKGINDDELSSFVKLTENMNVDVRFIEYSPFGGNKWNNNKMVPYSEMLRIIKSDFPELIRLKDLSNDTSKAYKVPGFKGQIGFITSMTKNFCSSCNRLRITADGSLKVCFFCCLIKKEATCRYVQSLQNAKSTHDFDWWLSIGQVSNKKVYLLPSAKTSQFLISQIAFTTSSAVNSVNDEIALTHTNTEGKIKMIDVGPKSPTIRIAKAEAKVHLGPTAFMLVEQNKIKKGDVLSIANFAGIMAAKKTSDLIPLCHNIQIHHVNLNLTLDPATHEVIIQSEVKSCGKTGVEMEALTSVAVAALTVYDMCKAISKEIVIKHVCLLSKTGGKTDFIQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWR7</accession>
    <name>A0AAV4MWR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_269231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002702">
        <property type="protein sequence ID" value="GIX76921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8333" checksum="78FDD6895C6C989D" modified="2024-11-27" version="1">MSNLVDDLQYGHAGGCQQTGFSIEATRLYALSLFTAVLCQMEITSRIIGVGLGLQSDARLLPDEKKHQNYTDASAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5L9</accession>
    <name>A0AAV4N5L9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_571301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003001">
        <property type="protein sequence ID" value="GIX80122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20377" checksum="0003EF40ADCBA916" modified="2024-11-27" version="1">MLWHDCWRKCGRINSTCSNRFRGRGFLPRKAYVQQLKQVQEKGKHIYQKGPRLEIIALAVCGENALTFSNRLYLPERPKTAAGSRRIIKKGPPPNHYADGKRWVTLTWRKINIPESLCCGMTVGENGCINSTFSNRFRKRIIYQERPTFQQQVQEENIYQERPTTRYLNVVAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAC3</accession>
    <name>A0AAV4NAC3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_265181</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003064">
        <property type="protein sequence ID" value="GIX80838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000515">
        <property type="entry name" value="early growth response protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF60">
        <property type="entry name" value="STRIPE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX80838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14968" checksum="B33C1F39388928A7" modified="2024-11-27" version="1">MSSKIEDQPGSLVKTTTNLAEASSEPVEPRNYSNQQKKGPVRDRLFTPAPSMTVPKRFIRNSDLNRHLKIHSGQKPFQCRVCSKSFFRSYYLIAHNRVHTGEKPYSCDTCGRRFTSNDAKRYHAKVHLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NB80</accession>
    <name>A0AAV4NB80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PGBD4</name>
        <name evidence="2" type="ORF">CEXT_552751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020743">
        <property type="protein sequence ID" value="GIX82072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NB80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="1">
        <location>
            <begin position="2"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="22183" checksum="B23D8861DE16527B" modified="2024-11-27" version="1">MKFLHFSDNSTFDENSHPNPKLRKIWPVFYDLMKKFSSVYTPERDLSIDESLMLFKGRLSWVQYIPLKRARFGVKLFVLAEAESGYIHNTIIYTGKSTIFDKNYENYGVTTKSVMTLIEPFLGKGYCVIADNYYLSPELAGILIRNNTDVYGTLRPNRRDLPENFNKITLKKGEIAAFQRGKIIVMRWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE00</accession>
    <name>A0AAV4NE00_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Snake toxin/toxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_4314_1</name>
        <name evidence="3" type="ORF">CEXT_331641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003196">
        <property type="protein sequence ID" value="GIX82040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23599">
        <property type="entry name" value="TFP_LU_ECD_Cold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.60.10">
        <property type="entry name" value="CD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045860">
        <property type="entry name" value="Snake_toxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035076">
        <property type="entry name" value="Toxin/TOLIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00087">
        <property type="entry name" value="Toxin_TOLIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57302">
        <property type="entry name" value="Snake toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043371719" description="Snake toxin/toxin-like domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Snake toxin/toxin-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX82040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="23160" checksum="A4B780F0F5BD7008" modified="2024-11-27" version="1">MWIIGFLFLLTPSTVLGLECYVCDNQDSNYDKCTKTIKTCDIAEDRCLSEVRWGSTPYWDSTGKTILHIQNMLHTERQCKSEIKLAVVVTEFGIMTGNVECCHGDRCNYYVTSKDYYRHFRSSLSLHAVDQTQAPVRMWFAPRLHQPVLSNTMKRKGDWPLCVILCCPESMCGCGMCALGETSDGSGGTPSRNSRDYYRVPTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJN1</accession>
    <name>A0AAV4NJN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_505551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020934">
        <property type="protein sequence ID" value="GIX84141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10634" checksum="C35BBD312DD714A2" modified="2024-11-27" version="1">MNQHGSSETLNHVPGLCGILHKLSINRTTCLIKHRRSELKENGAALREVFSTVANSQIVGREMELSPSPADIYILWIRIGTPVFNSSFENDILLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKY2</accession>
    <name>A0AAV4NKY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003513">
        <property type="protein sequence ID" value="GIX85426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12649" checksum="2A104E63EAAE5005" modified="2024-11-27" version="1">MLKQWETMDWMDRDVQIQSERKDFHLNATGGIGKYNNWRNLYTNKGDTNCGTDMPHKDPRHGIGRFGITVPPLPCAAGHMLLDNKCKMETHRSVQSNGGTFLRQKRGFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPH4</accession>
    <name>A0AAV4NPH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_622141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003621">
        <property type="protein sequence ID" value="GIX86815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="9057" checksum="71C47959F6E65D35" modified="2024-11-27" version="1">MSRFECEVISSGRKTEFDTIRNWKKHLCFIYQESGQSSLPYAQNIEVDFDQIMEFALEMNLDSFEEIKIINSLQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ56</accession>
    <name>A0AAV4NQ56_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_804111</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7"/>
    <dbReference type="EMBL" id="BPLR01021187">
        <property type="protein sequence ID" value="GIX86947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX86947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18363" checksum="25B6A97E207C356D" modified="2024-11-27" version="1">MADVPMHINEKCDNSEKLENLIYIDKTPFTSVTEGKAEVLFPSSHDVFYNPVQEFNRDLSIAVLKQFAKNPPKAKSKKEVKNCSDDNNSGIRILEALSASGLRSIRFAKELPNLEKIVANDRNTQAFLSIQRNIKHNKVENIVEAANEDASVSKFQTKVFLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXT3</accession>
    <name>A0AAV4NXT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_61491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003875">
        <property type="protein sequence ID" value="GIX89563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12436" checksum="C53016F87015A514" modified="2024-11-27" version="1">MHIEQSWSNSIRENAETLCYPNAFRTRMRIPRKHSERKICFSRLHKMEEFRLKNSFSFFRPLAGREKAFLFENESLSKKERFLINGGKNSDGIMEGIKSWPEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYY4</accession>
    <name>A0AAV4NYY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_623401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021433">
        <property type="protein sequence ID" value="GIX89520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9111" checksum="319C91E7C7A2EE58" modified="2024-11-27" version="1">MSGRESRDDVLCHSSAHKSHTRHRRKRSPFAGNPDRLVSIWPGMLIAYYDRFALRLGKCLQQRNLVGKWELMNQRSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZW5</accession>
    <name>A0AAV4NZW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_67751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003929">
        <property type="protein sequence ID" value="GIX90298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="8984" checksum="82E4935493FA6D71" modified="2024-11-27" version="1">MSVKKRKVNRNESSLSPGRRTPDGVNCPSTLGECFAFLVSLGPNPRGVVASPRTLLPTANKMKVLFTNCITLFSLPVHGTNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA73</accession>
    <name>A0AAV4PA73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_451841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021721">
        <property type="protein sequence ID" value="GIX92900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11461" checksum="240F062F5666163D" modified="2024-11-27" version="1">MKRMERLLELVKGAIRIDERIFYAHPGLHIYFIHEKNSPSARCNSVHKNPRSFYGLFDSHPTTLCTTSANERRRSKELLKARSRVQSHKPSRALKGCAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PEV2</accession>
    <name>A0AAV4PEV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_256161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004542">
        <property type="protein sequence ID" value="GIX95619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PEV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11520" checksum="550DEC4C20057392" modified="2024-11-27" version="1">MLGRRFFEEYSLTTVFPDVPIGHFIYHVETEVKYLQEREFMPDLRIKLLDEAVIQVQEEDAPQLFAEHVRFNPFDGVVRELQCREFQHGVVQHSAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLR4</accession>
    <name>A0AAV4PLR4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_269761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004610">
        <property type="protein sequence ID" value="GIX96117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24612" checksum="41A1F782A33511C0" modified="2024-11-27" version="1">MIFSLPQKKNSRLTKIKTFLRGPPRSEGNPISGHPIENRLQLTPKRHHFSRDLSLGRGFTTDPLSNVGVNLNNPVAKVHLDVLGVRLSVQMELSSTELTPSPGFINVNENPAAEYKFGPTQARKSLGLATESRNFTEDVIVEGIDNHISRRGEKLSQVRLRANQQSSKDRDVPSTDQIIIQRGRKPPKAETEPIKLKSDYTKLKIKIYAGGSNTKGTKIGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PMP2</accession>
    <name>A0AAV4PMP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_59351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004779">
        <property type="protein sequence ID" value="GIX97428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PMP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17549" checksum="6C4873B8AE894177" modified="2024-11-27" version="1">MVNASCRRDYHALMSRVKNKMNDRAKGRNKINKNGKSGNSTKSYEKSRNGHFKHLKLLFPKKGLQLLFYWRKDVHGLTDMKSCSQTTFHVQRASSAISENSFSEKSEKYERLWIMVTSIFGKTAFGVCESSLTCNGNQLFDCTFLASGACHSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQK0</accession>
    <name>A0AAV4PQK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_348361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004908">
        <property type="protein sequence ID" value="GIX98436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14486" checksum="31C77A2458DF2207" modified="2024-11-27" version="1">MEAYDLPGHRPRNGDQRENPHIFLHSGTQSSVMQQWLIGSLIIWPYATVIVSGALGCHNLQPSPAVIEALATHSHICCNNGDGKLSLYEHERTECCLLMSVLISPLKLYPELAGHLSIPQRAAHSVAQVQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PU28</accession>
    <name>A0AAV4PU28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_633361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005025">
        <property type="protein sequence ID" value="GIX99299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PU28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18883" checksum="2EB73378C7623714" modified="2024-11-27" version="1">MSDESSRGEYSSDDISDESSRGEYSSDDISDESSGDEYNSDETSRNEYHGYGFDDISDESPRDGYSFDDISDESSRDGYSFDDISDEMCVYEFKTLVADIQYKANKSANSRNSMNATTTSIFSCSNHPEEQRAIPSYSWPMSKLGSQSKQFSTTVERNYSPFSFMFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIB4</accession>
    <name>A0AAV4QIB4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_332161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006336">
        <property type="protein sequence ID" value="GIY09165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY09165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13264" checksum="151DE22CC6C9CC97" modified="2024-11-27" version="1">MKGGSARNSSPRKSDLLKSTSRRQMRQLKEPFTDRYYNNLSLFLPLIAFSLFATTPFNNTRKKQNLICLSLHPVAKCANLKNRSQTDTTTTCPFSPTLIAFLLFDTTPFSNTRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QP28</accession>
    <name>A0AAV4QP28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_586141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006542">
        <property type="protein sequence ID" value="GIY10589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QP28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8572" checksum="D30BF38CA8F26AAC" modified="2024-11-27" version="1">MAHSRFHVGGGRSEDPFGIHQGVVGGRWIHKESRELETAQGHSETVRGLTKKQIEKQHKVTPTSRKKNHCSQECDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXM6</accession>
    <name>A0AAV4QXM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_179251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006794">
        <property type="protein sequence ID" value="GIY12453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9698" checksum="6F98B5AE04E982A4" modified="2024-11-27" version="1">MTFKSDSSDAMGIPIQEFISSTFRDGESILNFFSEYSVDPFPEETIGKVTVTPYQGYPEADAGYQQVAPSRLQMPKQGVQRHHPAPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1Y1</accession>
    <name>A0AAV4R1Y1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_587611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007240">
        <property type="protein sequence ID" value="GIY15487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1Y1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10398" checksum="B880B3952B8BB655" modified="2024-11-27" version="1">MYEIIAILPRKGKSYRTADYWFINCKRRIIVPLKFGLRANNSNSRNKFVLQRNKHLTTSEITYNINLRRDSTISTTILKRCLAEAKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R631</accession>
    <name>A0AAV4R631_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_636541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007429">
        <property type="protein sequence ID" value="GIY16867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R631"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11660" checksum="EFCE8C9DA9E00392" modified="2024-11-27" version="1">MFSVALLWQQQRSFDLVYVMHLVLFTTICLATTMNDVQRRVTVATAAIIHSATTMNDVQRRVTVATAAIIRSGICDASRIVLQRSVATTMNDVQPVALPRQQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9J3</accession>
    <name>A0AAV4R9J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3730 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_22558</name>
        <name evidence="2" type="ORF">CEXT_448451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007418">
        <property type="protein sequence ID" value="GIY16812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060147">
        <property type="term" value="P:regulation of post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045163">
        <property type="entry name" value="Focadhesin/RST1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16212:SF4">
        <property type="entry name" value="FOCADHESIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16212">
        <property type="entry name" value="FOCADHESIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="474" mass="52794" checksum="BE20A96B1F76DF21" modified="2024-11-27" version="1">MEDLKQRLKFDDVAVRSRCVQKLVQAVKKKSKGELITASSVQIPELNLLWEVCIEESTSTSNLAIRGIIYLATNKHLDIDYVTNKFLSSLSSSSNVYNIVKGITRLLILQSNQLRENNRSPYSLRIPKHPLIAVLQADEDYLPLVLESIADAISENNLRGFQVMEPTLLDTVKNEPRTAFYILRCIPLLQIEDYSQVVEAANFIFKAQQAFSSLQSDENDRIYISELLLLSTLSLSERSVLFGHDPARLLHIAVNANFVSSYINLCLVSVAKILKTVSGELIERYITLAVILLNFPQISPTVAALLASSVIQLLPEPCVVSFDEISNSSLSQLLAKLEQSFLDCENVKSSIPSAEAESSKDAPSTSTGHEKTKNDNPIYIESFTSLAQSSLQCANFALKLDESNLEFKLNWLKSVQNIVESCETDNLDVIFSLVAALFLISLDDHTFIKSCLDTFESILKKNSFGKCKILLLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAE1</accession>
    <name>A0AAV4RAE1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_111744_1</name>
        <name evidence="3" type="ORF">CEXT_557521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007490">
        <property type="protein sequence ID" value="GIY17276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00473">
        <property type="entry name" value="PAN_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="223"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY17276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="582" mass="66010" checksum="DA4F60DEE8337731" modified="2024-11-27" version="1">MHSEGTEFGDGNTCYLLAPFANTACDFDSHPLPPTSQFTAFFPLLRLLTPEWASKEKSKWRKESRDARAHLIQVQGQRHFNRQESDPIRFVKRERRAQKLLNVVPQLSDLRFKKIFFNLFLIRSSSFECTCRWVNSVQASVRQAYFHCNMSAMFALRLNQLNEIKLIDDQSILNQDSSHAGSQRGVTTSPPSPPCSEHGPLSPTHKGQRRLLFRRCRAFDGSCSSGFITFELITGYVYTSPGDTMELVPGTLQLTECLSLCSANATCQAINFETGLCVLFSSSANQRPASLTPSQFPVFTIYAHKVCLLEEMKIFLKLFYFLPEPFLPHPFKPQPFLPGHSCPDHSFTDHSCPDHSFTDHSYTAIHARAVHHGIFIPGQPQALQPRLDVRAGERLRTERRRSQLCHRHVVARGLHGAVPQRDPIPVSICQLQQDDWRVLPQRQGPTSLSLTATNRHFGPSSESVDYLESNCLDDIFKPISRFITNLEINFLKTRVVFTVEQKKFGNQITDQGKISVTDEKHSKRTISVTRPSHSWGNLPNSERTQNNVQLESHDSFIPVTLFFGVVLLILVDRVPQGRPCPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHX0</accession>
    <name>A0AAV4RHX0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Sec20 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">BNIP1</name>
        <name evidence="13" type="ORF">CEXT_468121</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SEC20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007798">
        <property type="protein sequence ID" value="GIY19820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15865">
        <property type="entry name" value="SNARE_SEC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005606">
        <property type="entry name" value="Sec20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056173">
        <property type="entry name" value="Sec20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825">
        <property type="entry name" value="BNIP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825:SF0">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SEC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03908">
        <property type="entry name" value="Sec20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Sec20 C-terminal" evidence="12">
        <location>
            <begin position="144"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="48"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY19820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="235" mass="27041" checksum="F92EA4202CC0454D" modified="2024-11-27" version="1" fragment="single">FHSEKNLSNRKYNESTIRLIQQDIVKSDLHVKALVQDIRECLGPVEILNNLNMQVSENMKSMKQAIEELEILAREQDKESDKHDLLKNAEKYQKQYASNQFALRKANLATQALLDKQTKEELFERSTTATRKRMRADKESLSKQSSAITDNLTVIKNMMVTQVKQSEESLQTLIGSSGVVTETREELKTMGSIIHQSKTLLQKYGRREVTDKVLIVLAALFFLACVFYIVQKRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RK57</accession>
    <name>A0AAV4RK57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_577451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007915">
        <property type="protein sequence ID" value="GIY20630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RK57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21010">
        <property type="entry name" value="AGAP001581-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21010:SF3">
        <property type="entry name" value="DAXX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="18234" checksum="D90653B4DE0918E3" modified="2024-11-27" version="1">MRDIVADILRKHFLSCNPLTGSKNAPPFTCNQLMQKQEKIKDSFRNFVLIMDRITLQSYREAATVQQIEEGEHSAHQRPVPPPQEVRQPATRGAHPALVVPLPRMYPIFPEFYNMLKDMIKDVLRDPSYMEVCHEELRLLRFLPPSLRPPGASPRCDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPE1</accession>
    <name>A0AAV4RPE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Multiple PDZ domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Mpdz_1</name>
        <name evidence="1" type="ORF">CEXT_247611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008161">
        <property type="protein sequence ID" value="GIY22539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="17584" checksum="9E8A7E5F3353DBB6" modified="2024-11-27" version="1">MADFLPGDRLLSVNNINFRHTNFEMATQVLKHVPKGVVRLGIAKPTTLSKSVPAKISFKEPLETQQEIVPNGSTLKIFEYNGICHTYEEPLNMYGTRSQTPSSLFSFGNDSRCSTPFSSPGLSSSGKLWGFEIPLLPSALERIVKIKKGNNKLGDFCFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTJ4</accession>
    <name>A0AAV4RTJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Irregular chiasm C-roughest protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rst_0</name>
        <name evidence="8" type="ORF">CEXT_142951</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008440">
        <property type="protein sequence ID" value="GIY24712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005911">
        <property type="term" value="C:cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051275">
        <property type="entry name" value="Cell_adhesion_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11640:SF31">
        <property type="entry name" value="IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11640">
        <property type="entry name" value="NEPHRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY24712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="22219" checksum="76D1450946051642" modified="2024-11-27" version="1">MVKNRHLPSTICISGHVRNVVPKISRFLFTSILTSKSKKRSVQYGIEGEVVKLQCLIASVPPPTRILWSRNSQHVDIDNNDGYEIVEDKIARGGVKNILIIHNADEDDFGQYNCTVWNAFGQDSMLILLKKQKSLPMLIILAGVIGGIVFIVSVTIVIILCLRRKSVIKVPRARKHGRCNVALKRRQDGGYLFILKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6C7</accession>
    <name>A0AAV4S6C7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_347591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009003">
        <property type="protein sequence ID" value="GIY28919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6C7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10157" checksum="42B985D84BEC4081" modified="2024-11-27" version="1">MELGWSSFDGVPCKRSRSLVSKAANYRDIPMAGMGTVIVLLGIFFLGFSIMRGRERIFLWCVCNVADYVATYVMWQTPTTWFTLMSAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9D9</accession>
    <name>A0AAV4S9D9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_200087_1</name>
        <name evidence="2" type="ORF">CEXT_326001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009175">
        <property type="protein sequence ID" value="GIY30142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9D9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17486" checksum="C7B8CB230E33A7FD" modified="2024-11-27" version="1">MKRGQSAFEGNVFTEFVHTDNTDGFDYLLNMEQESRRPETTTYLCTNCGGTAPSQLPYFLYFVHYRVSQCSKNIVFFTSTEAENRSSTSTCITVVQTNKGTMEQKKHYRRSRTAAGRHERRCGIERHRMGGDVRDRGGTLQDYQEQNMKAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDY0</accession>
    <name>A0AAV4SDY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pumilio homolog 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Pum3</name>
        <name evidence="6" type="ORF">CEXT_415991</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009251">
        <property type="protein sequence ID" value="GIY30597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="136"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="200"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY30597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="608" mass="70348" checksum="F3D268CFBCAACAA4" modified="2024-11-27" version="1">MEKEEKNQKPYSDSDISKVAFTANNEPNLKENVRSESVENENVDNNVNLKSILKKRKNELEDPISKKKIKSDNLTGKERKILHLNKKEKPQNMKRKTDDSAKTNEVVKKDHLTGKEWKKLKMQKKGKGEQFELGQSLKNIWEELRREDCKPERKNQLLKQACDVLKGRVKEFTFAHDTVRVLECILAEGAENHRDLLFNEVKDDILFLAKSKYGKFLVQKILRYGSKTQKEAVRKAFHGKVVKLIRHTEAAETIELIFNEFANAAQRFELVQEFYDPTYMHFKTYEISSLAELFEKEPNKKQSVIQNMKEALLKMLDKSVIKHSIVHHILWQFMKHADSVSRNEMIESVKEIVHEILHTKDGARVGMHCVWYGTLKDRKVIAKSMKTYVAKIAMEEFGHRVLLALFSCFDDTVFLKKHIIKELIAKLLDVAQNIYGKKVLAYLLNPAESHYVHPQMRNILEEGEIKKDLNVRCSELKAAIVDPLLKMITSNIQNLFTDNSFCHFTLVVLKHADEHKEEAFKAIADLVLIKQKASLKNDVEFSEVLIQTVPNMVFKSWIECNRGAFLLVNLLETEIPAVVKRIKEELAGCKKYLSKKSYVGAAIVKKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SK22</accession>
    <name>A0AAV4SK22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_776931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009730">
        <property type="protein sequence ID" value="GIY34135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SK22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8350" checksum="7C25D5E74388D11D" modified="2024-11-27" version="1">MNRSFRGTTMDRRIHNTEWIHVLRPLAALEHGVAECLRPPRIAALGYGPIKVLIVGDGRFILGRNRADLIFGWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKY6</accession>
    <name>A0AAV4SKY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_654011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009854">
        <property type="protein sequence ID" value="GIY35078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY35078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14244" checksum="0F4DA808374C7671" modified="2024-11-27" version="1">MESFQTRGFADMEIAGAANPRWRYVAPDVTKSGETPGDRQAVHITLAVLFLTGAIVCLAGVIFVLRLSQLEIDGNEMRAMYKHRSWNFLGNFEKRTTKLGKAFIKLESFCFFFSLMTVLAVLCLGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SN17</accession>
    <name>A0AAV4SN17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_217331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009678">
        <property type="protein sequence ID" value="GIY33737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SN17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="23481" checksum="BEAEA7BC31AB43FE" modified="2024-11-27" version="1">MESITKDKITSPRRPSDDGYPMEFLIDMQNKEHKGDKSPPHIDYLRKQKSQMKMQETQTIELHKRQDQVTIPRRPSDDGYPMGFLIDMQNKEHKGDKSLPYIDYIREAKVPDENARNPDDVKSISAHKTFQVPQLSQSPFENPSVDYLKLWRTSQKTRSHHQEGQVKYPMEFLIDMQNKEHKGDKKPPTHRLLKGSKSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUI8</accession>
    <name>A0AAV4SUI8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_603911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010218">
        <property type="protein sequence ID" value="GIY37770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14498" checksum="C50F878786D53E72" modified="2024-11-27" version="1">MRESKFVVLGAGGGGEDESCVEISGRCLQQFLQTHCGRLLPTHHSITSRAIYVAAYEPFSPPVINRRASYQSIYDSISNESLILPLKQPIKISFRRDLTYLYLSTPSRATRDFVAISGIPNLDSGGIPLPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZC8</accession>
    <name>A0AAV4SZC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_272291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010314">
        <property type="protein sequence ID" value="GIY38521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10893" checksum="0A4A625298882A3D" modified="2024-11-27" version="1">MNQKSLIYKKPLKDLRESAQGILDESLSAYRNPDSLNGYPHKVPDDSKYGDNNFHLTDRNLRPVYKKSSITRNISPVENSRVSPPKTVEKSPFPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZJ5</accession>
    <name>A0AAV4SZJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Laminin subunit gamma-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LAMC1</name>
        <name evidence="5" type="ORF">CEXT_639381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010519">
        <property type="protein sequence ID" value="GIY39853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009888">
        <property type="term" value="P:tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050440">
        <property type="entry name" value="Laminin/Netrin_ECM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008211">
        <property type="entry name" value="Laminin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574:SF435">
        <property type="entry name" value="LAMININ SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574">
        <property type="entry name" value="NETRIN/LAMININ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00055">
        <property type="entry name" value="Laminin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00136">
        <property type="entry name" value="LamNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51117">
        <property type="entry name" value="LAMININ_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043562560" evidence="3">
        <location>
            <begin position="17"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin N-terminal" evidence="4">
        <location>
            <begin position="56"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY39853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="264" mass="29983" checksum="3EC7872B7CFA69D3" modified="2024-11-27" version="1">MATSVVALEWTLLVLASVVLSCARSQYQTQQQRELIFSEIHSSRDQPSRCYDEFRRPLRCVPEFVNAAFNVRVEATNTCGTRGQTEYCLQTGVTEAKKSCEICDAAAPHLAHPPDYLTDFNNNENQTWWQSETMFDGIQDPTQVNLTLHLGKSFDITYVRLKFYTSRPESFAIFKRTRPGVEWIPYQYYSATCRSTYGLNDTSFVTYSDETKALCTSEFSDISPLTGGNVAFSTLEGRPSAYNFENSPVLQVSTQIDYGVYRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T199</accession>
    <name>A0AAV4T199_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_412481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010319">
        <property type="protein sequence ID" value="GIY38540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T199"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13617" checksum="5EE35F1C4AC1FE4B" modified="2024-11-27" version="1">MGEGGTIDIWLLGGPNKWSLHRWLANGKSLYQGSQGDDKFYRSILSRWGNDTTSLIPGGKDRNLPRDVGDTSRFLPARNCEISDSSNCFPFPLRTALICGRGQHSGIIMHLATGEEFGQYVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1R0</accession>
    <name>A0AAV4T1R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_68701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010641">
        <property type="protein sequence ID" value="GIY40643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11658" checksum="6EA6CD00BE5B674A" modified="2024-11-27" version="1">MHNNQKPKFSKQFFCAPTTQINKDFFLFRVNSPFVFPQRLQAEWPCALSTCKFQGFVLHPKKCISASRNTNATFTSTQTTRKLHTPPFCLFFILSSCTSPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1U7</accession>
    <name>A0AAV4T1U7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_346031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010430">
        <property type="protein sequence ID" value="GIY39219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1U7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043528697" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11872" checksum="02947A707233159F" modified="2024-11-27" version="1">MNSKKARSIACNSLFIYYLTFSLFLPPSSATISFSMVRAQEQQQEGIEVISLYHKTQQPTMGRSKEKKKATENETFFPPVTLSAEKYSFLLLTVISGRVGKGGARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEU6</accession>
    <name>A0AAV4TEU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MAGUK p55 subfamily member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_07590</name>
        <name evidence="2" type="ORF">CEXT_149071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011170">
        <property type="protein sequence ID" value="GIY44620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8109" checksum="F5F82A0413130503" modified="2024-11-27" version="1">MANFVNLSPQRFLWSPADRADLEVGDEILEVNGRSLDNCTHTEVISHIHQCIRSRTICLRVKRKTSCKLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THD0</accession>
    <name>A0AAV4THD0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dehydrogenase/reductase SDR family protein 7-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CG7601</name>
        <name evidence="5" type="ORF">CEXT_325431</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011199">
        <property type="protein sequence ID" value="GIY44812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05332">
        <property type="entry name" value="11beta-HSD1_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004825">
        <property type="entry name" value="PRK06181.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000126">
        <property type="entry name" value="11-beta-HSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY44812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="37075" checksum="019992D14ADE83CC" modified="2024-11-27" version="1">MIGSETESEEVPKTFQVIYSTMIHWTRLIAGGLVLPIVFPWLVYTLYKSHFKNKIFRDKSLEDKVVLITGASSGLGEALAHAFHRAGARVILAARRKDALEKVKNDLITKYQSKNTPAVLPLDLHDLKAIKEKATKALDFYGHIDILVNNGGVSFRGEIVDTDLEVDLRIMVTNYFGPVALTKAILPSMLERNSGYIIAISSVQGKIAIPFRSAYSASKHATQAFFDTLKSELSHTNIHVCVVSPGYVHTNLSLNAVTARGETYGVMDHTTATGMDPNEAAESIIIATAAKRSELVLAGILPKIAIWVRVLCSWLYFYLMGSRAQRIRAANTIKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIU7</accession>
    <name>A0AAV4TIU7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">NAAT1</name>
        <name evidence="18" type="ORF">CEXT_431341</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011396">
        <property type="protein sequence ID" value="GIY46305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY46305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19345" checksum="38FF7C531D6AE522" modified="2024-11-27" version="1">MTTYKSHLDGESVLEDMLTGQQDGCTSEIECRHTYLTWMENHPWQPAGRLTDQQAERGASKAEEEEEVPTRGKWGKSIQSLLLCISMSVGLGNVWRFPNVAYNNGGGAFLIPYLLLLVIIGRPLYYLELILGQFSSQGPIKLWRVVQHLKVLDMLKYYLCLLWLYFTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TL29</accession>
    <name>A0AAV4TL29_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_745791</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011376">
        <property type="protein sequence ID" value="GIY46151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TL29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF9">
        <property type="entry name" value="LEUCOKININ RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="62"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY46151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14653" checksum="4A02C9E57A363012" modified="2024-11-27" version="1">MHQHGTENVEIMNGTFQNISMNLSVTNDTVSSNNDVLYDVPPAIIILLSCCYGLISLISIIGNFCVLVIVFTSRRMRTVTNYFIANLAVADIIIGMFSIPFQFQAALLQRWVLPAFMCAFAHLFKYYQSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TN50</accession>
    <name>A0AAV4TN50_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BPTI/Kunitz inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_159772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011383">
        <property type="protein sequence ID" value="GIY46182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TN50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000020">
        <property type="entry name" value="Collagen, type VI, alpha 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF374">
        <property type="entry name" value="BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="7">
        <location>
            <begin position="82"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY46182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15406" checksum="566D7F02B986B14D" modified="2024-11-27" version="1">MFNIRSYSFVHKLDSLRKLDMLFLHAGNFVCLRTPTARKEILVYGYIPAYTPGALDSCLAVPIPLLFRLTPAQPNYDNIPRCMQPPAAGLCLAYFPSFYYNPSTKKCESFIYGGCQGNQNRFINEEQCMKACGGRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TPZ5</accession>
    <name>A0AAV4TPZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_132681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011632">
        <property type="protein sequence ID" value="GIY47819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TPZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17126" checksum="2C3BD464CD5B3C04" modified="2024-11-27" version="1" fragment="single">SGALSRSLSRTNFVLFHSREKNVRKQNITQLEPEFVLIVNVVPLEEFLLEPTSGFHGYSKPCGGPRQSTYDRFPFERLPTLCEKHLQVYGRCREKNIQKQITTTRIRFRSYRRRSTIGGRSKLLSEKQAALGRLEYFTNHYVGDTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQN7</accession>
    <name>A0AAV4TQN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_72791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011602">
        <property type="protein sequence ID" value="GIY47617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12327" checksum="C53666E055927090" modified="2024-11-27" version="1">MGGIEKGVRYSSWCLVEMVVMGDVRKVEGVSRGLFVTGENPSKNKVSSLPKKCNIKVALETNDLPPVYSDRRMQSIKVEPRAFWFGTPPKAAGFTSEIITLKTSDGDSCINGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TR80</accession>
    <name>A0AAV4TR80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_780681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011656">
        <property type="protein sequence ID" value="GIY47991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TR80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="18293" checksum="F6D63A94CEDC83AD" modified="2024-11-27" version="1">MEVGFMSAPAYRWSSLTFSLRKAKEKFRVRKNAKTFSQQNQIFSAVDFSWSQGSRFYVRPGLSPELSDFFALKNNLYTVCARLQPIGIYGTHSKNCCLPFFGIQGDIPAISWDKFKARELNNSQKNKDMAKIEKSIEQIESFTGWKQQEYESTLMEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUV3</accession>
    <name>A0AAV4TUV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_42831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011862">
        <property type="protein sequence ID" value="GIY49649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9277" checksum="72568449E22C3C55" modified="2024-11-27" version="1">MIAAGRKVSKFSGPEEQFEDNLSLRNKGEKAPSFDSFRLLPKFSYLPTFRRKWISHFGDKTEGGSRYFLPTDFLKVLNDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6M1</accession>
    <name>A0AAV4U6M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_517551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012362">
        <property type="protein sequence ID" value="GIY53402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14668" checksum="DED870199D49CC26" modified="2024-11-27" version="1">MPPLCHGMKMSATLPMSALCTTSLSDLDRRPALPLSGRNPPKNQWTVRTPTCMTAFRALRNWMTHDSARHPRDLMSLGFSTGNSMPLFGGAVARNGPDALLSTVESSSTLQKRGRFLSLYKFQFAAIVNTFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U818</accession>
    <name>A0AAV4U818_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G-protein coupled receptors family 2 profile 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_267656_1</name>
        <name evidence="1" type="ORF">CEXT_462941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012439">
        <property type="protein sequence ID" value="GIY53948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U818"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="22629" checksum="20F1CDD0E89BFE23" modified="2024-11-27" version="1">MGLFTHEFSCERTVHVVTEPPGNTPTCPAEKYLEVRWSKTAANTEDIQFCPKGYTGKSGDTAILKKDDEAVWGEPDYSRCLSSEFLVIQDKFESLRMGYLITEVGTLMQELKLYLWNMRDRFHIAEGEPVVDLLEGLLDYQRKHGKSDENQFKNNSQIFLDIVSFLLDSPRLIQKQSVSKRNFLVRKHEIRECTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8S4</accession>
    <name>A0AAV4U8S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_98031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012475">
        <property type="protein sequence ID" value="GIY54153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8416" checksum="254FAA4FDFA62FA2" modified="2024-11-27" version="1">MDGVSMWKGFMAVKTAGGKSAQLGSFSLILQLTMLKELKTKTLVSRKDSAVTNNLPSNWTGDEEKANHLGLRFSAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAW6</accession>
    <name>A0AAV4UAW6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Atp6v0a1_3</name>
        <name evidence="10" type="ORF">CEXT_255181</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012567">
        <property type="protein sequence ID" value="GIY54898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016471">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY54898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16268" checksum="7445EDBE8459C840" modified="2024-11-27" version="1">MGKVAGDGVIHDNPPSETKQEEFDLPDMCIHQAIHTIEYCLGSISHTASYLRLWALSLAHAQDEVKNENSKKETKKRASDFDCCFPSDIFPHFCIPFRNEDEKLSFGGARSHAGGQMQPPMASAGASGFPREVFGDLQNYAQFWKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWJ9</accession>
    <name>A0AAV4UWJ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Choline O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">chat</name>
        <name evidence="6" type="ORF">CEXT_81471</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.6" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01013577">
        <property type="protein sequence ID" value="GIY62108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004102">
        <property type="term" value="F:choline O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008292">
        <property type="term" value="P:acetylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007274">
        <property type="term" value="P:neuromuscular synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF14">
        <property type="entry name" value="CHOLINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0530">Neurotransmitter biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="5">
        <location>
            <begin position="88"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY62108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21658" checksum="92544A1FBC0DB108" modified="2024-11-27" version="1" fragment="single">LCNDVDLFVHRFTKYGKEFIKKHKMSPDAFIQVALQLTYYKVHRKLVSTYESASLRRFYKGRVDNIRAATAEALAWVKVMCDAQQVTTINGEGPDNHLLALREIAASKNYPDLPLYQDKSYWEFLNFRMSTSQLPTKYGILVGYGPVVPDGYGCSYNPCDDHIDFCVSSFFSSKETSSDFSPTVWREAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBV4</accession>
    <name>A0AAV4VBV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_16151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014279">
        <property type="protein sequence ID" value="GIY67750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9587" checksum="6C3BEEA5AE6F579A" modified="2024-11-27" version="1">MNIEEGKRWLGKASFTILSVMFLMSWFELNVFDVTGAVFVVKKMKDSGYDWINYDWNQTDPLEVEMLGYGFILLIIYFHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHI5</accession>
    <name>A0AAV4VHI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_152131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014544">
        <property type="protein sequence ID" value="GIY69508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9361" checksum="D79DD62FB9013EB6" modified="2024-11-27" version="1">MWGILENKDRGHSRTYVEDIRGQKIFPRRDRGHSRTERSFPHRGRRHSAQRTFPSRDRDIPLVDRGHSRTMIDIPAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VI75</accession>
    <name>A0AAV4VI75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylyl cyclase-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cap</name>
        <name evidence="4" type="ORF">CEXT_645111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014614">
        <property type="protein sequence ID" value="GIY70000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VI75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008179">
        <property type="term" value="F:adenylate cyclase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019933">
        <property type="term" value="P:cAMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.330">
        <property type="entry name" value="Adenylate cyclase-associated CAP, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028417">
        <property type="entry name" value="CAP_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053950">
        <property type="entry name" value="CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036222">
        <property type="entry name" value="CAP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21938">
        <property type="entry name" value="CAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101278">
        <property type="entry name" value="N-terminal domain of adenylylcyclase associated protein, CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01089">
        <property type="entry name" value="CAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="3">
        <location>
            <begin position="234"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY70000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="393" mass="43285" checksum="FE85412F74A2A100" modified="2024-11-27" version="1">MAVAQRAISDFEQLINTSLQNFAGKVSHAFQRNLELIKYGLYNPQPPMDNEQMKTYANEIRSIVEFRESPKDSSFTNHFSTVREAILALGWINVKPAPTQYIKDAKEAGEYYGNRVLSSNKGNELHKQWVNSWNQLLMDLQSYVKSNFLTGFTWGSGQGKGGAAPPPPPPPPPPALFADAPPQGDNARQALLNDLNQGANITSYLKPVKKDKTAGGAAPVSLHSPVKVQTAPRPAARPPKFALDGRKWVVEYQRSQYGLRVENEDMSQSLAMFSCQDISLEVANKLNSVVIDSCKNSLVVLKSIISSVEVIRCDRLKIQCDGIVPLINMDNCDSVQIFVTPASRGVEVISSKTTSCNMCLLEPDGDYKEIAMPEQIKTVLVGEKLVSSVVEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNG7</accession>
    <name>A0AAV4VNG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_540621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014840">
        <property type="protein sequence ID" value="GIY71678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9373" checksum="80EAABA629B2A27E" modified="2024-11-27" version="1">MLPIFNFISMWPFLENFKRKYPFYVREESHWMDEVLPSGKTFRNNITGFAYKMEEALKATSVFNQCHISIKMHSGVASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRF7</accession>
    <name>A0AAV4VRF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_427271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014892">
        <property type="protein sequence ID" value="GIY72048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="27" mass="3137" checksum="8B9C375A5C4DA1A0" modified="2024-11-27" version="1" fragment="single">RHLSVLAHYRDNEMSSESVNGSLKEMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBM2</accession>
    <name>A0AAV4WBM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_702961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015954">
        <property type="protein sequence ID" value="GIY80027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24106" checksum="F09CB1C427209230" modified="2024-11-27" version="1">MINIRWMFETTLAKKESHFQHHMKSSQKIHPIWNKTLSSISSSDFSKTLKIVEREKTSSASTWQQIFQTQNEFHPNNFYLYVSIIQKEAPPNGVPFQALEPLSKVIPTSKKKTKIQEGISKESNKLRSSPSSPDYSAINGIRTKCPEDPGVIVVPKEASFAYRALSLLKDLPSMAGGIFSFIGLFQRSIIHNPSFPDWGFGILLSQSFDCLHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWE4</accession>
    <name>A0AAV4WWE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_237691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016762">
        <property type="protein sequence ID" value="GIY86206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12098" checksum="C998887394EEBBCD" modified="2024-11-27" version="1">MDAVDENRNRKRVNDLEVLESLHVGERFPQDRGVCPKRPSPPALSRSNLSRKQLPLRFVHITRPRVTDRGQPCLREEVEVVSRPKDIQWTRWTRIETGNELMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X010</accession>
    <name>A0AAV4X010_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_734451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017012">
        <property type="protein sequence ID" value="GIY88022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X010"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19522" checksum="945A286BFE12B3AE" modified="2024-11-27" version="1">MVVTLSYVFVIGAEQTRLAIGLTWLAGCGIREYAYSYIERKLSVRHRFSRVAFEEFTQNRHKQGSFNSTPLTEYAIRSSPITCIDKQSFDLTLFPSVVFGNSTIKDIYQETYRFDMVCPLHHRKSLSVRHRFFRMTLRSSPITGIDKKVSIRHCLGTEYGIQGVRPLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X412</accession>
    <name>A0AAV4X412_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_279651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017096">
        <property type="protein sequence ID" value="GIY88725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X412"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043887422" evidence="1">
        <location>
            <begin position="19"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9561" checksum="B9D58F421C704A51" modified="2024-11-27" version="1">MTLRKLWLVVSVFSLVESCYKFPENVKDPCEEKECHFGAQCRPSLDGTTGGVRVSRKMCHVWRQQGFTSSMRKRWTRLPKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4M3</accession>
    <name>A0AAV4X4M3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_154332_1</name>
        <name evidence="5" type="ORF">CEXT_707641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017158">
        <property type="protein sequence ID" value="GIY89120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043607502" description="EGF-like domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="686"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="51"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="322"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="636"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY89120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="727" mass="81534" checksum="EFF4F2134E57E7E0" modified="2024-11-27" version="1">MIFLSVLTHICIQILLQNALCENVKPAEELTFETGEELKFEIEDSLADDEYEGACATDKDCQYGGECIIFRSTKFCDCKPGLEGDRCEIITDCVEKYKNCTEDYGICWYNEILQEAVCTCPQNNSFDDQEYACKACDCGDAGYCSFVNGRKTCDCVPGYASHYGTCEACDCGPHGYCKFIDGLKTCKCQHGYANYAGECMRICNNESNGECQNGGMCMQFSYDGDTFSLCQCKKFVTGGRCEIVEDCATGIYQNCTGENGVCSYDQQKEDAVCTCYGNRSLHDQENICKECDCGGKGNCSFINGNKTCECIEGHADFGGFCKETCQDDSECQNGGLCKVVGGSKFCECKTGIEGDQCETVIDCSYGRYRNCKKENDTCFYDQQKETAVCICSGNKVLDPYDGICKDCDCGVYGVCSFNWGKKICSCSPLTAEKDGKCVECDCGSYGIGIYEGGTKKCICSPRTVERDGKCVVEDYDSTTNSPKLTTPTTITEQDCDCGNYSHHCTLDRYGRKLCLCHFGYTQINGYCYWKPTERPETTTTTPTLKDCYCGRYSHQCYLDRNGRKLCLCHFGYTQIDGYCYAKDEFRTTERPRPRTSTTERPRTTERDCYCGKNSYSCYFDWYGRKECRCRFGYVQIDDYCFGLCTNFTCFHGKCQVLGQTYECICDTGYTGARCETKIETKSENNVLFYTVIASVAVCTFLLLSTIFCICLYSFFVKRKNKNSTVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5I2</accession>
    <name>A0AAV4X5I2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_353831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017145">
        <property type="protein sequence ID" value="GIY89044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5I2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043898883" evidence="1">
        <location>
            <begin position="26"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13205" checksum="E9BB7CD5AC226529" modified="2024-11-27" version="1">MCLRPIWRSLLAPCYSLLLFYDCWIEYTREQGTEFPCFSLFKEGTWDTNSSWDKNVFCTVIALLLLSPPMAGGIDLQADGNKLIEYSTNLTQTDGSTLDMNMMNNAVKRLRDDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8L8</accession>
    <name>A0AAV4X8L8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_17274_1</name>
        <name evidence="2" type="ORF">CEXT_6561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017292">
        <property type="protein sequence ID" value="GIY90109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY90109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="365" mass="40585" checksum="440538DE9060D381" modified="2024-11-27" version="1">MSGNIHDKPSYRDATLNGKRLKFKSKRSKSAKERPTSFSPNGSLPKSATTISSRHLYPSKFSSLSDKSSSVFSYGDEDINKSLSRRPTTAHVRRKAYKTRLELKLTSTSEARTTYESSKSAKRRPRTGIVKRNKSPAKLAGSEDWLNSNTGKLDKERTSETLDDDDDETVCGTVSHQSHKNSKPRPKTAVGSRKKSPTKLTASEIRLESFACELEKIIHLRDILESDDSSNGTSAVSLSSSMEDVSEDDDRKPVRKTKSDRNLRLAMSKKISAEKLKPVSWVGPKITAALEEDKMFLESILKNKGRLQVVPLPSRLIRVLQTTNRWIASATLSASLLIGAKKLSDVYQLYFRAGLSRTPVEMCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8T8</accession>
    <name>A0AAV4X8T8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_146881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000027">
        <property type="protein sequence ID" value="GIY91602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8T8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10159" checksum="A975B6FF66C2C7FA" modified="2024-11-27" version="1">MENRQPKKKRMFYYTRRNGHVIKEHWHNTSNLITDLLQNHVDVHAFSCCHNSVAHPQKKMLLRIKEAGHTGTRTQPLVRKYVRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9P1</accession>
    <name>A0AAV4X9P1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_765871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017464">
        <property type="protein sequence ID" value="GIY91867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11277" checksum="618DD6321EEDFF50" modified="2024-11-27" version="1">MVRRDMIPLCSDTKAGVFNEDGRGTSLSLENGRRLRHTQLPIIKRHERGCQMPGRAGVARIEAPIGFYGGAEERIMDGRRFYGPLGGGDGQRHGQEWGRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC82</accession>
    <name>A0AAV4XC82_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Moesin/ezrin/radixin homolog 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Mer</name>
        <name evidence="12" type="ORF">CEXT_796901</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell junction</location>
            <location evidence="3">Adherens junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Microvillus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell projection</location>
            <location evidence="8">Rhabdomere</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017460">
        <property type="protein sequence ID" value="GIY91805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005902">
        <property type="term" value="C:microvillus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13194">
        <property type="entry name" value="FERM_C_ERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.10:FF:000002">
        <property type="entry name" value="radixin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000013">
        <property type="entry name" value="radixin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011174">
        <property type="entry name" value="ERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011259">
        <property type="entry name" value="ERM_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041789">
        <property type="entry name" value="ERM_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046810">
        <property type="entry name" value="ERM_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000798">
        <property type="entry name" value="Ez/rad/moesin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019747">
        <property type="entry name" value="FERM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018979">
        <property type="entry name" value="FERM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018980">
        <property type="entry name" value="FERM_PH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008954">
        <property type="entry name" value="Moesin_tail_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23281">
        <property type="entry name" value="MERLIN/MOESIN/EZRIN/RADIXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00769">
        <property type="entry name" value="ERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20492">
        <property type="entry name" value="ERM_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09380">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09379">
        <property type="entry name" value="FERM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002305">
        <property type="entry name" value="ERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00935">
        <property type="entry name" value="BAND41"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00661">
        <property type="entry name" value="ERMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01196">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48678">
        <property type="entry name" value="Moesin tail domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00660">
        <property type="entry name" value="FERM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00661">
        <property type="entry name" value="FERM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="11">
        <location>
            <begin position="1"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="305"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="511"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)</name>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)</name>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR002305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY91805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="580" mass="68213" checksum="0B4387A9597E7FAF" modified="2024-11-27" version="1">MDAELEFDLDLKATGRDLFDLVCRTIGLREVWYFGLQYVDSEGFVAWLKLDKKVRDQDIRKKMPVPFLFLAKFYPEDLSEELVQEITQHLFFLQVKQAVLNMAIYCPPEASVLLASYAVQAKYGDYDEATYKPGMLANEDLLPQRVIDQYQMTPEMWEERIKIWYADHRNMTRDEAEMEYLKIAQDLDMYGVNYFPICNKKESELWLGVTALGLNIYEKTNKLSPKITFPWNEIRNISFDNKKFTIKLVDRTSPSFQFYSSKIKMNKLILDLCIGNHDLFMRRRKPDSMEIQQMKAQAKEVLVRRQIERNKLSREKQLREEIEREKADLEQRMLQYQRGSQRVALEALRRSEETAELLAEKARIAEEEAMLLTQKASDAEVEIQRIKISAIKTEEEKKLMERKAHEAELLATRMVQESERTAKEAEKLKEELIKAQMSEKDAKEKLHEIFKNSYSKSYLSNSPVEVLNIVPRQYSELQVEPSMNVANNSATYDLIADHEMEKLTLEIEKERVEYLEKSKHLQEQLLELKTEIEVLKVEDNITSLDHIYEDNADRGENKYSTLRRTKSGSTKTRVAFFEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIR0</accession>
    <name>A0AAV4XIR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_471561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017870">
        <property type="protein sequence ID" value="GIY95076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="8973" checksum="5793C5F0421C38F9" modified="2024-11-27" version="1">MPTRCNTQSSSCCFAANECSTPVAAVQPVGKNYNIICLAPIFPLVGLLPLGRAARSGSAVSVAHSSDSLGGVHGWRVGSDSPRLVACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIW2</accession>
    <name>A0AAV4XIW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000319">
        <property type="protein sequence ID" value="GIY93870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9892" checksum="DB1CC94CE784D73C" modified="2024-11-27" version="1">MYVCDELRNKKFMANPDLKRKKVILKLEEGEEKESDALKILVFEVIQRWKMSVAPSVTEAKAKVFGLTPCVILPSLSALPHKSFLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL13</accession>
    <name>A0AAV4XL13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017967">
        <property type="protein sequence ID" value="GIY95827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="7947" checksum="606B5D9D6AE02D24" modified="2024-11-27" version="1">MTGESISTWGGIGLMDRRALFRPEDISPKPRRGFKEKGFSGARGVGRGIALAGLKETGNKKVEKKSGAARKGDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM22</accession>
    <name>A0AAV4XM22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_210621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000498">
        <property type="protein sequence ID" value="GIY95270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="61" mass="6865" checksum="EDBE119DCE59D8B5" modified="2024-11-27" version="1" fragment="single">SCKSCDIQCVHSGKLLIHKSWNALHISILLQKEEIGHVRQLMSDGLVPIQEMGRAETRGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMA9</accession>
    <name>A0AAV4XMA9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_47881</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RING-box family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017848">
        <property type="protein sequence ID" value="GIY94954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031462">
        <property type="term" value="C:Cul2-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000010">
        <property type="entry name" value="E3 ubiquitin-protein ligase RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="75"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY94954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15020" checksum="6B9C32BC6FDBE3B2" modified="2024-11-27" version="1" fragment="single">DTSLIFKTLIKCTMASMEVDEEVDNETTEMSATPSTSRGEKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP00</accession>
    <name>A0AAV4XP00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_429511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017947">
        <property type="protein sequence ID" value="GIY95670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10300" checksum="1258BD212ABB0E3C" modified="2024-11-27" version="1">MVTEEGYMKLALKVTEVSWQSKEIHTVVNELLGRGSTIFSKLHHWLRTSCIFTQGPDSLNKWQLPSGGSDFAKETTEAPKYKADSHPLSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP88</accession>
    <name>A0AAV4XP88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic nucleotide-gated olfactory channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Cnga2_1</name>
        <name evidence="2" type="ORF">CEXT_394311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000572">
        <property type="protein sequence ID" value="GIY95760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="236" mass="26063" checksum="CA0C2B5337998F98" modified="2024-11-27" version="1">MQVKTDYQPSSFTNDGSFAKYGSINEISKGDNTKTIKLLSEKIWDINPALDYSFSNETLVNHQIVFDGNEEITWSTRFKDEFSLTDSLNLNVHTIPEESEEDIHEASANSCSNNGISQKHRNLSKDSAIGSNAVTPHESDTAKTQIPRTCSVDNLSSVISKQHLSSVDAEESQGMKRLQSAPGSLHLENLQAGEAIDFLRMASMSSGFSYSDDTSSRRNSWTWGSEGDTDEEYASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRW8</accession>
    <name>A0AAV4XRW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_673561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018215">
        <property type="protein sequence ID" value="GIY97796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14327" checksum="0BF7426C7AFA4683" modified="2024-11-27" version="1">MCLCLSPKTAATLKCCYHLYLPTNLSSSTDEDLLLQSPPDPFEITYPFRIEQKEKIKPFPKCVPDIAGSRTISSGPALLIWKRISLVCMRFPCANFICPPMCDFHIDPFVFCGLASVYRLGDFFWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTN8</accession>
    <name>A0AAV4XTN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_21521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000924">
        <property type="protein sequence ID" value="GIY98411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10734" checksum="03C4E59E81C11492" modified="2024-11-27" version="1">MDAFNVTAFFIKNKEKKLFFCKEYPSQKLVLPQNASLTISGTFIWRLKKTYLFGTEPHYNLLRTLREEYSIHNKLLWLLRPFFSDHKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU90</accession>
    <name>A0AAV4XU90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000964">
        <property type="protein sequence ID" value="GIY98770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9945" checksum="BF9A09928A6BF213" modified="2024-11-27" version="1">MSYERMMQQRLQGRLELAKELQSLRKSRIDRSRTFSSCVCVNYYCVHKAKNYTHVLQSTEKSRAIASALSGAGNRGVPFQSGVATDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUT0</accession>
    <name>A0AAV4XUT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_800541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018231">
        <property type="protein sequence ID" value="GIY97940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="22909" checksum="0059AFE41C9CF33E" modified="2024-11-27" version="1">MRLRYLNQHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLHGAMRMRYLNLRCNENAIFESIRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXE9</accession>
    <name>A0AAV4XXE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_47271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018317">
        <property type="protein sequence ID" value="GIY98596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9502" checksum="B26A84F6721C6420" modified="2024-11-27" version="1">MAENSVIWFDDLRILCKPERSVPRLKGFKCKPHYRWFSRPARGMARKQSCGGLEPRPQIRVPGSNGSVLLGGAPDKKAAPEPSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZX4</accession>
    <name>A0AAV4XZX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_595571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001146">
        <property type="protein sequence ID" value="GIZ00315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="20975" checksum="74A850B12F361A61" modified="2024-11-27" version="1">MPLLSRYSRDGSCPEPPVARMPGLHQIKNFSLPRIHLSRNSICSLLVPSPPLLFGRHQISRDKQFCAKEGGEEISFAPLDLQNLFTAPSTGFKTIWNRSSLTSEINRSTRLECVTGEASWTITKLSGGNGLMISILKQIELIRNQMRETESKVLCPYHCKSVSLRIFTSVSKTSGENAIQMFDVTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7H9</accession>
    <name>A0AAV4Y7H9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat shock 70 kDa protein cognate 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_156901</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018921">
        <property type="protein sequence ID" value="GIZ03222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7H9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000135">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000134">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000003">
        <property type="entry name" value="heat shock cognate 71 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="612"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="616"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00072095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIZ03222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="648" mass="70871" checksum="25890363B9DCE765" modified="2024-11-27" version="1">MATVPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTETERLIGDAAKNQVAMNPSNTVFDAKRLIGRRFEDSSVQSDMKHWPFEVISDGGKPKIQVEYKGENKSFFPEEISSMVLTKMREIAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGTGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFVQEFKRKHKKDLTSNKRALRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYSTITRARFEELNADLFRSTLEPVEKALRDAKMDKAQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILNGDKSEAVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTRQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEEIERMVQEAEKYKDDDDKQKSRIAAKNSLESYAFNIKSTVEDDKLKDKISEDDRKKVIEKVNDTLKWLDSNQLAEKEEFDDKQKELEAICNPIVTKLYQSAGGAPGGMPGGFPGAGAGAAPGGGSSGGPTIEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7L9</accession>
    <name>A0AAV4Y7L9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_643941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018812">
        <property type="protein sequence ID" value="GIZ02441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="15718" checksum="FA2E3C4271BA7461" modified="2024-11-27" version="1">MTNKSVRNRREGKDNTTGSGSTGEDNTTSDRSTGKDNTTSDRSTGKDNTTNDRSTGNDNTTSDRSTRKGNTTSDRSTGKDNTTGDGSTGEDNTTGDGFSEKGSTTSVGSPGDDSTTVNGSLGERLQGRQLISRREQYDRRWISMRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7Z0</accession>
    <name>A0AAV4Y7Z0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_356831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001471">
        <property type="protein sequence ID" value="GIZ02546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="374" mass="41365" checksum="9847355D24174D91" modified="2024-11-27" version="1">MICGKIDVREGMGEEEGRARGGRGRGVRGGGAQRAALEPLRFSQCWRWPQAGFTYLEQLWRTGQLKGFPQLQNGGRVGIPVRKTQKDTRSVIPRKKGWQRVERCACAAVGKATDTHRSARDLEQLESFINQQPASQEGALLFCFSLSRCCSSLGMGMSTASGFGRCQVGACAKLGSWMLPLWRIFFRPLLGFWNCTRFKLHDGNRPLNTVDVLKLRYSSFKAKVMHDTSDIHPTDLNSGGNTGDNSRTETNSPFKNNRFLKTSRKGMGHDKRGRTFRGASLLPDSQKTTPPSLPSNTMDLRSPRPLTTRRPPGACAWTPAAKHFETGHRHHSAGHPGAPEQQPPVPSRPRALGEQYSPLGCLDILMSIMCYAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y819</accession>
    <name>A0AAV4Y819_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CXXC motif containing zinc binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Czib</name>
        <name evidence="4" type="ORF">CEXT_104411</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001475">
        <property type="protein sequence ID" value="GIZ02576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y819"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ02576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18274" checksum="1836CAB1F2AE5431" modified="2024-11-27" version="1">MGKIGLQIKAILENVTDLEAYGEDFRWYLKLKCMNCGEEPNKWQYVSLSEKLPLKGGRGEANFVSKCKLCARENSVEIFLDSFQKYTADDSETFKTIVAFDCRGVDPTDFSPRIGFRAVGETSGTIFDDIILEEKEWVDYDEKSKLSVSVCELEHKFVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8F3</accession>
    <name>A0AAV4Y8F3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_293741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001463">
        <property type="protein sequence ID" value="GIZ02470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8F3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7596" checksum="5DE952FAA6D868CB" modified="2024-11-27" version="1">MKAGLISGVRQTAALTADGEREKRDLFILGIGSRHARSAKQDTLSFPYSNSPTLLPQQTPKPPILKIPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBM8</accession>
    <name>A0AAV4YBM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_369041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001785">
        <property type="protein sequence ID" value="GIZ04723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13100" checksum="0007F4CD85F92DDD" modified="2024-11-27" version="1">MSRIPQHAIIRSGQESPLLFLRDKRKRVCPLTHIGFVLQEGYTARGRGVRDPPPGTSTLEFPSVPSKGASEVTAPIDAKFVYQDPTAALVQFSVNIPILFAPHSNRNLKRKSYGTSSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YEM9</accession>
    <name>A0AAV4YEM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_82521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019155">
        <property type="protein sequence ID" value="GIZ04856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YEM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12527" checksum="F2E0D291B78085EA" modified="2024-11-27" version="1">MWENWPFQSVNDKLQENPTARHGFGKKKKKMSSQRPTIHPSAFRFGAYFISLFYFLPPLLGTPTVRRPFALKSIGRNAMKEKKEKKNRAQFLLIKRENTGLPMVLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M441</accession>
    <name>A0AAV4M441_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_251061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019348">
        <property type="protein sequence ID" value="GIX66887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M441"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12948" checksum="3A62A7A828916C88" modified="2024-11-27" version="1">MSIESLHENVTDSDSKSEFVPSCTLLGMPPICQDFDQSSEKSGIQLQVSSSNTLECSNIYHVHLLQLPSNPELRFGYKWFLNEADESQRFLTAQLTEHKELEEEQRKKGQNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCJ6</accession>
    <name>A0AAV4MCJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_182411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019596">
        <property type="protein sequence ID" value="GIX69555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8808" checksum="86FB5CCABFFAA0D2" modified="2024-11-27" version="1">MDFHVSIIVKEEEEKKQTSDAEHHVPKKQVLDSEVLPVSSRNKAISTWRVINKGGGDSKLRHVIGFSKPDYGWSLSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEH1</accession>
    <name>A0AAV4MEH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_78601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019556">
        <property type="protein sequence ID" value="GIX69209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="36156" checksum="421680CE7D3E0E02" modified="2024-11-27" version="1">MSKKKSLDLQIFDDQPSSTTLIFHLMPSYALPPRREVLYSEKSFPQPICNCSFSDDQHTNLSHNALLSTPTPKRSSEKSFPLANLQVFVSIIGFKSKNWSMELTFDTGSILKHFFYSLSRFLRLQRLRRVLFLSLEKRKKKKGRKFGIKTNVQGGELFTPTRMDPEFNFQQEGYYFSLRGVWKDYVFFSAGSQKEIYRQSTSLGEDLEKLNIFPGSLRWRNICYRPQTLFHHYNLSPNAHLSTPKPKKKPSILRVLPLATLQLFVSIIGFKCKELVDGATFDTGSILSLFFSFFSRSRFLRPRGCGAYYSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MF99</accession>
    <name>A0AAV4MF99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_321521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002147">
        <property type="protein sequence ID" value="GIX70515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MF99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9297" checksum="E67FA0ED601B32C4" modified="2024-11-27" version="1">MNQWGFAGCVMNVRVTPYFSYNKGCRNWQPDLSPVKVPQAGHSHTIPVGACLGSRLPRASCMVGHVVNSLPFSYGRYCWRHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ML24</accession>
    <name>A0AAV4ML24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfotransferase 1C2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SULT1C2</name>
        <name evidence="4" type="ORF">CEXT_39791</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019757">
        <property type="protein sequence ID" value="GIX71489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ML24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="170"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX71489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="25525" checksum="A6A473EBC66AAB42" modified="2024-11-27" version="1">METVQIAEQIKKRLDCLVSFYHHTKNIVGYKFKNGKFDDYFELFMEGKVDFGDYYDCLLSWYVHRNDPNVLFITYEQLKKDTRTYVMKIAEFMGQKYKDMLENDEQLLNDVIKYSSFNFMKETLNRDVAELAALPKDTILNHPDIPQGMKDLLVGKDEDGPGFFDSDPNSITFVRKGIVGDWRNYLSPEQNQRMDERFRERTKGTDIPELWKDYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUG3</accession>
    <name>A0AAV4MUG3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of very long chain fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Very-long-chain 3-oxoacyl-CoA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Elovl7</name>
        <name evidence="11" type="ORF">CEXT_460941</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="10"/>
    <dbReference type="EMBL" id="BPLR01002649">
        <property type="protein sequence ID" value="GIX76096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF69">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX76096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="272" mass="31966" checksum="06C86B5B2784EEFE" modified="2024-11-27" version="1">MLIADPRMAEYPLMKSVHLTVVFSGLYLLFIKVIGPQLMKSREPYSLRHLMIVYNIFLVIVNLWICTTIVTSGWLTTYNWRCEPIDTSRDPIPMRVVLACWVFYISKIMEYTDTIIFCLRKKQSQINFLHVFHHSSVPITAWLGVSYGPGGYNTIFPIANTFVHVWMYLYYGLAAIGPEVQKYLWWKKYLTRLQLVQFVFVYLYFLQLALFAPKSCKVSPFLIWISLGQAIIYFGLFMNFYFKSYKRKTPKQDIEDSLKHENGHVISKNKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVL3</accession>
    <name>A0AAV4MVL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_138051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020258">
        <property type="protein sequence ID" value="GIX76517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13775" checksum="91F12E76BB63686C" modified="2024-11-27" version="1">MLCFCYAIKYVPKGDDALSGLIFIVFSVYPTLSCIWVYDTGLYMGVPYLLIYVWVCDIDVLYMGERYCLYGCTILPWGRSDVILPCIWVYNDSLYLVCDTACIWVFDTILSCMLRYPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N337</accession>
    <name>A0AAV4N337_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002843">
        <property type="protein sequence ID" value="GIX78501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N337"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16412" checksum="145D398016DE9FFF" modified="2024-11-27" version="1">MWKIKVFKHHLPPYSMSMANKETSQAMPKDLVLLSGGLSFSGGTKLIQIPSRHLFPNAALKYNLSSPIISKNYRSQKSANRPLFCIPLTRVKRYCKYLPTSAIPGCYPHLTSKYCFFSACFQGNKETSQAMPKDLVLLSGGLSFSGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5E6</accession>
    <name>A0AAV4N5E6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_610701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002996">
        <property type="protein sequence ID" value="GIX80047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5E6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7838" checksum="47DB29A0D8DE852B" modified="2024-11-27" version="1">MSVRHSLFRFLPGHFCARLANGDREGLESGNRFVVGSLKRGGNKREKSVFEAIPMTEMKITGRRGLQDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N718</accession>
    <name>A0AAV4N718_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_515771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003041">
        <property type="protein sequence ID" value="GIX80518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N718"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9489" checksum="15399C4A83F8D4AC" modified="2024-11-27" version="1">MCRDIWGLKKDSIFARKEQKPPALASPGLEIVFQSAFLNSLKLKYWTSVFHLWVVWVRMAWVWCGHSGPFVLRSCLFYVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAW2</accession>
    <name>A0AAV4NAW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_567071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003091">
        <property type="protein sequence ID" value="GIX81051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16779" checksum="2741260E17BA1361" modified="2024-11-27" version="1">MYHRRELVVCVGRTPSKVGRQNDGFGFPPVQSLRGLRSVGRADCNGRAFINKLTKNSPAFAPPPLRSNLVLIPLSLTAASTPSRSFSLSPVFPPSPVLFRWKEGCRKKSKKFAFYRRRGERCKKNRRGRERKKFRQKKEKKKWFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBR2</accession>
    <name>A0AAV4NBR2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_724391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020659">
        <property type="protein sequence ID" value="GIX81245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10649" checksum="D16259C47E8C51E5" modified="2024-11-27" version="1">MFVQYCRWIPKFSERIHPLLGKIHFPSQKSLGMLFDYLKIVVVGGSLMAIEQNMSFKVETDASEFAIGATLSVLILYKYFDEEIYHLYMIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEC6</accession>
    <name>A0AAV4NEC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_191731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020838">
        <property type="protein sequence ID" value="GIX83167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14690" checksum="632F7C6BF8F7BA71" modified="2024-11-27" version="1">MVTSLCVGGGQEKHRQVDVKSNKSFGFLVGWGDVSPLSVLKLATGDWPCIMRHEVRLLLIRIQRIVLLASVDKHSVRPLSRMSHNSDEVERVDVLTKQILQSLRMKRILEDRNSLRKQIHDITVRVLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJI9</accession>
    <name>A0AAV4NJI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_516081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003455">
        <property type="protein sequence ID" value="GIX84838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14140" checksum="A910FDDA57EF1FCB" modified="2024-11-27" version="1">MRLICSSISHWEEEIRGSSCLNSPPQVLSHFRQIWWDPPSLRDLTHLPPKTSPFFPTAPQLRPPNHPPGANDGPAGSGMVANRKRDHSVPEPADEEKFEKSSVEGGGWLLACGVCPTTLIGFATLHQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNT7</accession>
    <name>A0AAV4NNT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_706351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003488">
        <property type="protein sequence ID" value="GIX85199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17652" checksum="2915E9F1A9DFD00D" modified="2024-11-27" version="1">MSLGGMYTDLSSGPSPEGFFYMKVEDSEYTYYLKCCWCGYPYVRSLPVNVYGDNVTPSNVGRWSWISHSPNDESSANSSWGRGSHIPNDESSANSSWGRGSHIPNDESSANSSRTRHHDMRDARNFAIERAAECNRSLGPCHCKCPQRHPEGSGEEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ70</accession>
    <name>A0AAV4NQ70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_801381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003557">
        <property type="protein sequence ID" value="GIX85910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9325" checksum="D5465E37ECB52115" modified="2024-11-27" version="1">MQGLRISDTLPHPYLRTTPFAFLPQSFLQHFCTAFFTSLRSSRLLRKKKKKTTKIWKRGGRVWIDTFTAFLSPFLCAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRJ1</accession>
    <name>A0AAV4NRJ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">NEDD8-activating enzyme E1 regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Nae1</name>
        <name evidence="7" type="ORF">CEXT_183291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1 5">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021223">
        <property type="protein sequence ID" value="GIX87298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01493">
        <property type="entry name" value="APPBP1_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000475">
        <property type="entry name" value="NEDD8-activating enzyme E1 regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030667">
        <property type="entry name" value="APP-BP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039099">
        <property type="entry name" value="APP-BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="6">
        <location>
            <begin position="18"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX87298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="533" mass="60310" checksum="99577160B59E01A6" modified="2024-11-27" version="1">MAYAGDNRYEGSPKRVKYDRQLRLWDDHGQYALEAAHVCLVNASACGTEILKSLVLPGVGAFTILDGKIVTGEDAGCNFFLDKESIGKSRAKVSTEHLLEMNPDVRGEFVDETLESILQAEPNFFSKFTVVIATNVDENALLKLADKLWDQGVPLLVCRSYGMVGYMRVQFSDRTIIESRPENEFHDLRLDRPFPALQRFVDAVDLAKLTDQEHAHLPFVVILLKYLEDWKSSNDNQIPKNSKEKKVLKAEILKGARKKDEENFEEARRAVNKSITDTTVPSEIQSILNDPLCENLTSESKSFWILAKALKEFVNNEGQGCLPVRGIIPDMTSDTQSYIKLQNIYKAKAEEDAHTIYVKVQQLLSNLGKPPNFISEQEVKIFCKNSHCLRVLHGRSIRDEYNPNASNTQSLIAHLEHEDSNIVFYVLLRAVDKFYSTYCRYPGQTNDEVESDIVKLKNCVTSLMNEWSCSPIMKDDYIHEMCRFGAAELHSIAAFIGGCAAQEVIKLITGQYVPFNNTLIYYAVNQSTSVYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUW0</accession>
    <name>A0AAV4NUW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_116641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021335">
        <property type="protein sequence ID" value="GIX88546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10078" checksum="72426E2E1E398834" modified="2024-11-27" version="1">MAAVLFAINVGILYWLEKRDKAVPIPLSFFPFIQHSPFDSSIKENSYNNRQPEKPPSRNNAPSYFAVEVVKCTEGKDVTRTINCSRSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWA5</accession>
    <name>A0AAV4NWA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_680371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003834">
        <property type="protein sequence ID" value="GIX89185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="32" mass="3524" checksum="006907DE430C0D1D" modified="2024-11-27" version="1" fragment="single">MIQALVLTFGPSPTISHDSSKKKNILRLAEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAA0</accession>
    <name>A0AAV4PAA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_634751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021653">
        <property type="protein sequence ID" value="GIX92067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18148" checksum="5FFE4CDB16DCC2D9" modified="2024-11-27" version="1">MVFSVEKADDDSSLFEEGTYLASQHAFKHLGQRLWQEGVLSFDCAIQFRCLCMNGDPTLSLHAFFGVDSFHSDNWTSLNLSRVKSLQSAKINTPCPRGRRVLNACVFRTLPKASFSVRTSQFLRVGLLSPFACKTRKRILWRVAEIVVGMCFFGLHSHAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PMY7</accession>
    <name>A0AAV4PMY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_572771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004960">
        <property type="protein sequence ID" value="GIX98767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PMY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12184" checksum="9D003D9DF69C2416" modified="2024-11-27" version="1">MKIRSLVTQGILRKKTNRIPYSVRKTENSFVTVSVRRMHSDAVIRNCILRWLPGFLEKTGWLTEGRLSSSKASEYVSREKYLIAGSHTCTKGISRDVTVIYYDSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUP0</accession>
    <name>A0AAV4PUP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_134181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005109">
        <property type="protein sequence ID" value="GIX99876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043495404" evidence="1">
        <location>
            <begin position="25"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9223" checksum="AB09A5415F5C16D2" modified="2024-11-27" version="1">MENFWKSEGFLILIISLCVWPTIASVIDNNVSEEIPSEHRSAVEEAEAVKQLLVRLIPEKAHEILIEVDYEFHNKDAFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PVA7</accession>
    <name>A0AAV4PVA7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nephrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_562771</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005089">
        <property type="protein sequence ID" value="GIX99734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PVA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="448"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="31"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="131"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="224"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="329"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="524"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="628"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX99734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="78223" checksum="40EA490FA946EFF9" modified="2024-11-27" version="1">MTVPFTRARPQTRSSNRVPTMLSPSMFLYKPEFETKPLQQYDVIEGESTTINITAKGNPSSINYSWSKASSSPSLMPADSNDVAVTPLLSTGSLFNVTGVRRDQAGQYRLEATNEEGSTFVTVVLNVLYAASISMATEYALVDQGSNAFLECQVDANPLSDDVIRWQRPNFDMSRTKQSIENGRSYLIINNVTREDSGIFLCVADNGIGNEAQKASTLVVKHKPVIQRSGAHSKSAGSEGEDVRIICQASGAPNVSFTWFRDGSTIASSKKVSKYEIKSRHLDFITYESTLIVKDLKPQDYGDYECIAKNDLGFESFKVPLGRKSAPDPPISLNAINTTHNAVILTWTPGFDGGMEQMYRIQYRKAGSTGGYTVVDVDGQNTTVFTVGGLDLGTEYVFGIMALNNLGGSTYLEDAASAVTLSKQKPPIGETEKVVDQALTSKGDIPRIIIITVSVVGSCLLVLNIVLVVCFVRKRRKKRLEEGRASADEDQDLCLFSMESDHSSSKAATIEMYAPSSYNEGLNGESLSCNSEKSDNYSDGHSAGGYSEEQVKSETTAYITAHADGAYIADSSMPYYCPYPYPDQVNLDDRYDRSGPVPNKLLYGAEEDFYTNALRRNAYNLKLGDRPDTYEKGMYPPPPPGRTAASGAEVHHPPPSSDERHYVPYPSGATTSKPSPALSTFNPHLQGSPLHSTPNQCNHMPPAEGVIVHSEMDGHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2V4</accession>
    <name>A0AAV4Q2V4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_18661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005512">
        <property type="protein sequence ID" value="GIY02856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2V4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9176" checksum="5F7B917B1D3E4DEF" modified="2024-11-27" version="1">MNEISQYCEAGMKLMSGPQSVTCAAKREGAYRGSVGSKEVRLKTMTQKSKTSFLYLKPDFIRTYSCQSSVRTEPFKWSFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3T2</accession>
    <name>A0AAV4Q3T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein virilizer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VIRMA</name>
        <name evidence="2" type="ORF">CEXT_159101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005610">
        <property type="protein sequence ID" value="GIY03655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036396">
        <property type="term" value="C:RNA N6-methyladenosine methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026736">
        <property type="entry name" value="Virilizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23185">
        <property type="entry name" value="PROTEIN VIRILIZER HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23185:SF0">
        <property type="entry name" value="PROTEIN VIRILIZER HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10807" checksum="9126FFFC4D6FBA29" modified="2024-11-27" version="1">MLIENFAFFSHSTIGSKRKYSPLINPSLIDVNNKRPFIAPMRGRGFSRATSHSSRANDPFRSRPPNTSRPPSMHVDDFVALESHHSGNSSQAQTNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5T4</accession>
    <name>A0AAV4Q5T4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_487641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005621">
        <property type="protein sequence ID" value="GIY03789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5T4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="18841" checksum="99163604C8F72F47" modified="2024-11-27" version="1">MLQCCLRGHSGCLPKSMPSLPSFSGGKASHATSIPPTMVTGFCARSRYRQAETLSLVAIGLDSVTCQYQLSSSQVGKSGNPSSKECVTPLEESPISTSSKHRGNRGPSYTPRSEDAQVRPVNYNQIPRGFDEPLRRTVSPLQHHPEQALHGKNVYYPCDETAEHVVRDEQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q754</accession>
    <name>A0AAV4Q754_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_461471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005683">
        <property type="protein sequence ID" value="GIY04197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q754"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18824" checksum="CF8F37AAFC28A251" modified="2024-11-27" version="1">MVVFYLILDPHFFSTVGRTLSAKSKRRSLQEGGLYVRPPVLCVPPKHEVFALQHANELRIALQNDSRSILYTWKEVHTCHLSSNIFQESVLVWEEGMFLNRRNDLNVLLLGTFKSSTGVTCFILLFACVLSQLAILLFCKQIKLSSDLPSSCTSYLKRKTLVQME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QC44</accession>
    <name>A0AAV4QC44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_179961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006029">
        <property type="protein sequence ID" value="GIY06979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QC44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11632" checksum="826BB0150567C8BF" modified="2024-11-27" version="1">MAEVGIKRLQERKENSFGAFYFFLFHERVFLSFPSGLACRGMARKGSWREMCGLLQREMGPFYVGSKHGQFHSVKEFCEEPQRKIHLICSSKCCFQKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QD04</accession>
    <name>A0AAV4QD04_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein TEX261</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TEX261</name>
        <name evidence="8" type="ORF">CEXT_497531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVP26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006068">
        <property type="protein sequence ID" value="GIY07207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QD04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097020">
        <property type="term" value="F:COPII receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007277">
        <property type="entry name" value="Svp26/Tex261"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144:SF0">
        <property type="entry name" value="PROTEIN TEX261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144">
        <property type="entry name" value="TEX261 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04148">
        <property type="entry name" value="Erv26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY07207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="201" mass="23148" checksum="EA66B53415EF47D2" modified="2024-11-27" version="1">MWFLYLLSWVGLVIQISFIILSVAAGLYYVAELIEEYTVLTCRVIRILILVTMAIYGGVFLFEDLTASMIICGIISQVMHLLVLRTFPFFDLTSFPFIGAVVFVIINHYLAFQYFSSVYYPFSQVLSYFTLCLWLVPFSFFVSLSANENVLPTLAETRPLNADESDVVTNYFSRRSKRYGLLSFFNYAKESVLPQRVKKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QLB7</accession>
    <name>A0AAV4QLB7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ribonuclease III</fullName>
            <ecNumber evidence="5">3.1.26.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="primary">Dcr-1</name>
        <name evidence="25" type="ORF">CEXT_654931</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01006419">
        <property type="protein sequence ID" value="GIY09706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070578">
        <property type="term" value="C:RISC-loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004530">
        <property type="term" value="F:deoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016441">
        <property type="term" value="P:post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031054">
        <property type="term" value="P:pre-miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10843">
        <property type="entry name" value="DSRM_DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02843">
        <property type="entry name" value="PAZ_dicer_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000015">
        <property type="entry name" value="endoribonuclease Dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000005">
        <property type="entry name" value="Putative endoribonuclease dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.260.10:FF:000002">
        <property type="entry name" value="Putative Endoribonuclease Dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044441">
        <property type="entry name" value="DICER_DSRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048512">
        <property type="entry name" value="Dicer_platform"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20932">
        <property type="entry name" value="Dicer_dsRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20931">
        <property type="entry name" value="Dicer_platform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="14" id="KW-0347">Helicase</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="19" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="17 20" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="18" id="KW-0943">RNA-mediated gene silencing</keyword>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="24">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="PAZ" evidence="23">
        <location>
            <begin position="234"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="22">
        <location>
            <begin position="825"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="22">
        <location>
            <begin position="1069"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="21">
        <location>
            <begin position="1295"/>
            <end position="1317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="GIY09706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1321" mass="150871" checksum="5E2D0A19B51126FB" modified="2024-11-27" version="1">MAVALQTCIELHKSGELDDNLMPTGKEAVKSEDFLLDDADDCIRKDELPQQQSLSSKCNSEIVDETMKKDEEPRKTVARPGTTKRRMYYFKKVADALKNSLPVPNQLCYLYSFDMKLTCPIPEEQNTRGRKIHDPSNTLRRFGILTCNPIPPICSFPVFTRSGEVTVSLKPAASNLLLSEEKLESLAYFHRYTFSDVLRLEKYPMSYRPSESDASFYVVPVTLNYRNELVIDWKFADLILQQKVVKPKKPSEEERKNFAFVTEDYQDAVVMPWYRNVDKPQFFYVAEICSTLTPKSDFPDMEYESFEAYYEKKYDIKIMNHDQPLLDVDHTSARLNLLTPRYVNRKGVTLPTSSEQTKRTKRENLQQKQILIPELCTVHPFPAYLWRKAVCLPCILYRLNSLLLAEQLRLLVANNISIGIKELPVEFEWPPLDFGWTLADILTVQAEEKGMKKADESKDIFNQGLKNGYISSVDAETIFNGNTYNYSEVGNDNSNVMDFEIDVFDPSKVYIPDDDALLEQELNEINFNMGEPLFDTNNFPVSYSGSDYPSQPINAFPIWQPKSDGNDENGSQVRCGSPSFFEGSGWDSEWDTEDTDTPFLSVDLQGLGYLFAPGINMQSLSRDLALCKADDGWDSMDDDSFNSDDEENLSFTNLNNFDQNNLVISKISKNCEEVCECSWLTCSAYKEELLNVLDNSYEDLDENVTSIVMELKECKKKELSYLYSDVDNENSVKKSSFDEILETVVQCEKSLIPNTILTNCDIEQDVDNVVSTGKNEFSVNKSERTLAFGELLPDREHHQLFDNMNRVSFDENPDLSQHPGPSPSIILQALTMSNANDGINLERLETVGDSFLKYAITVYLFCMYPNIHEGKLSYLRSKQISNFNLYKLGKRKGLGELMVASKFEPYDNWLPPNYIVPKGLEEALIESGIPSGSWNLGNWSDLTQMSEEEIRQSIIDRTRMQCFEKAISISNDPMNTSSLIPYNLLTQHSIPDKSIADCVEALIGAYLISCGSRGALLFMSWLGLRVLPTIKSTKDNNIIEYGFLQPPPPPILTQEPKSTLKLEKLLSGYSAFEKKIGYYFNDKSCLLQAFTHASYYYNTLTDCYQRLEFLGDAVLDYLITRHLYEDPKKHSPGTLTDLRSALVNNTFFASLAVKYDFHKFFKAISPGLFNVINKFVQLKEHNSRLEDYLQAYYLEEEECEEMEDVEVPKALGDIFESVAGAIYLDSNMSLDTVWRVYYSMMKPEIEYFSNHVPKSPIRELLELEPQTAKFERAEMTVSGKVRICVDVFGKGQFVGVGRNKRIAKCTAAKHALRELKKNKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R280</accession>
    <name>A0AAV4R280_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_267341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007080">
        <property type="protein sequence ID" value="GIY14411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R280"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12031" checksum="B54FB3908EF8F35A" modified="2024-11-27" version="1">MINISLKRKFRKPFENYRRKNSHNLFFKIHLWSFAAPTIFCISMVAAAARGTNHPGGKYERRKWINRRDLGHFHPFQDAILQTFVSPGTFIIADFSRMSLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R374</accession>
    <name>A0AAV4R374_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GLE1 RNA export mediator</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Gle1</name>
        <name evidence="13" type="ORF">CEXT_739181</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007366">
        <property type="protein sequence ID" value="GIY16378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R374"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY16378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="241" mass="27243" checksum="282F118A573843A6" modified="2024-11-27" version="1">MPEISMKNMSSDSAIYNFSTYLIAKQFVEQGDTQISAQHSTAFPIAMAILGIWSKKLDVGSLILGHFYSRCPYLVPFYPPKQVGQSDVEYYTMLGYHVDDEGIIEEKHKFLNRISGYVRLYAAIISAPLPPSLKAQHPHGLVCGWKWLARIINLEPRPDITATVLFDFLDVAGHSLQKVYGKQFKKIIHILCKEFFPKIKQVTPGGTGGPIERLETFLQQTAKKGYISPPNGFLDSNFWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAC2</accession>
    <name>A0AAV4RAC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_95821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007568">
        <property type="protein sequence ID" value="GIY17956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="15542" checksum="5570555DF6365A25" modified="2024-11-27" version="1">MPLKEKLYLPKLITILQPYPLTTTWRITSHHSHRTLTKPLFHTVPKRAEKKPQKEVTRERIRKRKRKKKIIGKKRRKGSYGEREKKFSSKTDRWETGNECFWVKVNFTAILETGNVRIREKGWCIRSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGW0</accession>
    <name>A0AAV4RGW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_220461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007928">
        <property type="protein sequence ID" value="GIY20725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8099" checksum="C291D2DA961E819A" modified="2024-11-27" version="1" fragment="single">MLVNASTIEEAKALRAAFCDNDETGDEIENCFGQLKKMEVPEEPRKCCPSVGDRKTDQKSETGIATTQQKLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RT62</accession>
    <name>A0AAV4RT62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_708041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008259">
        <property type="protein sequence ID" value="GIY23292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RT62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9382" checksum="CFD13BEAC9A8FACB" modified="2024-11-27" version="1">MSSSRSSSVCRRSHHAERVLGGKHAYFMKLGVSVSVYAGLTRGEGFILLSNIGWLRNTCTTNQIYSSVALFAPHAMAYSYEGYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV46</accession>
    <name>A0AAV4RV46_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167223_1</name>
        <name evidence="1" type="ORF">CEXT_671031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008549">
        <property type="protein sequence ID" value="GIY25489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="631" mass="72598" checksum="E9C4C9BAEAE0887D" modified="2024-11-27" version="1">MSQKLQEKPPSRLCFETSDSRYQISIFLKNARKMVFEKAPNLESLLLPQEGNMFHHYSKNWSQKEKYRLRQGSLTFKERDPITDRGGSRLNEGQERGRCCRRCLLSAPCIFERDLTSAFRILGDHGDSDSGYDMCQFQTVVNMRAGLWSQCQENPFTRVPPKIVDKFREFIFSLNFRQLPNHEALHLLFTSHRLKKLDLSCFYVKEGETFSADDPYSPPHLKEDIDIHVPMNELTGDEYSYYCGIIPGGTDICLRTKKHMEDECNSLLYMLSKDPQPDLQSYVMTKTITISKFALQPLIQVSTNLTEIHTYIHWVKLNVVMNCKMLRILRLHTSPSAWFFDCPKQVLETCEKVLPSLENLEIFTICNREIDCFGMHQLAAIALAHCPKLTSVGHFNSAMAIDFLKSKTNKSHTGCFRLKKCFWGFGARCESPFRLNKVLNLKSSFPELIKTAVSCCPFVEELILQVVNKDCLQHLRRLKRLNSLVLECSYCEDFEIDECLSSLGEITHQLKHFVIKGINRFTIGSSLPLNVVSDNCGNLETLGVLDNSAIIFPLKIYASFRFLKRIFFITSLDYLGQILRYCDNLTYLVMIGHFTVDESELRKNLSHTSALKLQTLGINSPYFSKCHENGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1E1</accession>
    <name>A0AAV4S1E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vesicular glutamate transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SLC17A7</name>
        <name evidence="8" type="ORF">CEXT_766451</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008745">
        <property type="protein sequence ID" value="GIY26886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060076">
        <property type="term" value="C:excitatory synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030672">
        <property type="term" value="C:synaptic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005326">
        <property type="term" value="F:neurotransmitter transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098700">
        <property type="term" value="P:neurotransmitter loading into synaptic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050803">
        <property type="term" value="P:regulation of synapse structure or activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035249">
        <property type="term" value="P:synaptic transmission, glutamatergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000003">
        <property type="entry name" value="Solute carrier family 17 member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF456">
        <property type="entry name" value="VESICULAR GLUTAMATE TRANSPORTER, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY26886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="18888" checksum="90EEC64FA1643A03" modified="2024-11-27" version="1" fragment="single">WHFRRLTPSADDYCGSNWWLPCRLLKKTRISNNDGVRKLFNCGGFGMEAIFLLVVAYARNHVAVMFGLILAVGFSGFAISGFNVNHLDIAPRYASILMGMSNGFGTLAGMICPIVEENLTNLGTPDEWQRVFLIASLIHFAGVVFYAIFASGEKQPWAEPPDENNPDEGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2Z2</accession>
    <name>A0AAV4S2Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_781941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008774">
        <property type="protein sequence ID" value="GIY27107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043977494" evidence="2">
        <location>
            <begin position="23"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY27107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23174" checksum="5C432AB42EA350AD" modified="2024-11-27" version="1">MLTTLAVLDRLYWFFLSSTSNCKRCDPAPSNIPKTKPLDRHYREIEPDKHFRILIVLHVEKKFTAMTDTMARIFNNTCDPDPNHSREAGERRPDGEEGEPTKVGRDWSANISSPSLASQSPCGGLFRTDFRGVKLAEVQKRKRGERRVPTGRRSVPMPLPKHPPYSQLYSLIFTLPCGYGLALVMTKEILTVFSDKLDDPSLSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBB1</accession>
    <name>A0AAV4SBB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_278091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009115">
        <property type="protein sequence ID" value="GIY29705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14560" checksum="E7058117C33814BD" modified="2024-11-27" version="1">MKLARLLKISKWSKKKKAEYYIISCLILLLNHIKKWQIWKTLEAAKTNIDKILSSLENFNMRSRLRSMSDMIDAMGLRRQGEFANHISQNLAKINVETGQGVLLMTLSGGDTSSVWVHVVQVHWCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SD04</accession>
    <name>A0AAV4SD04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_91191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009428">
        <property type="protein sequence ID" value="GIY31864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SD04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043439219" evidence="1">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9905" checksum="98B05B5201BB751C" modified="2024-11-27" version="1">MNSLGLSFTAVLLLLGVASALPNELMSALKHMPDLTQPENTMMGQSLKEMGVEICRTNCTCVRQPPTAARRKTESGTAVQRLLLMHPTTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUJ4</accession>
    <name>A0AAV4SUJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_215911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010074">
        <property type="protein sequence ID" value="GIY36669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10702" checksum="9332CE339EFFC815" modified="2024-11-27" version="1">MVPEKTKRSPFSVDGTVPSLETKSMLRWRVGHSKINFFEERRLMGQILDRLAKGAIYDSIKVFPLEVASSETPIQRRGAIIQSERLVKFRSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZI9</accession>
    <name>A0AAV4SZI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_660481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010302">
        <property type="protein sequence ID" value="GIY38426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15709" checksum="3F74E60A1EE8EA82" modified="2024-11-27" version="1">MKRCLRSFLEDVCRIWNFGKCLEFGYGEFGGGNIVWELAVLEDACRISNLYLAEVISKVGAGIGSYGIPHHNANRQIAMAMLTHIPIQESCNLSQMWHQSRIHPLWCCRVNRDSSENMSFYTCVDVCCSQTIIEQSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T162</accession>
    <name>A0AAV4T162_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_711821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010388">
        <property type="protein sequence ID" value="GIY39009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T162"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14058" checksum="1A97BF3729DDD933" modified="2024-11-27" version="1">MEPGDKPEDLDDGRGFLRYIYEGHVNANIQYNVRNQTPQFRHALTLVIDNNFFKPKTSALCQQVKSLNRPLFVDRDYCVSESTSPLGQRVTTLNSDRESDKWPEASLNGSRDLSITLRGRVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5L1</accession>
    <name>A0AAV4T5L1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_33371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010653">
        <property type="protein sequence ID" value="GIY40747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5L1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11839" checksum="68767234B88C53BF" modified="2024-11-27" version="1">MVHVVPLTCTQWYAHAPKHKRYYTAKRVGQGRWKEEKINKNGRPLSLRNASDINGPPRVTDGVTGVHPESLLFGHWATVALHSSLPWMSPLGELGRGGPGQKIFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T6N7</accession>
    <name>A0AAV4T6N7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_803441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010784">
        <property type="protein sequence ID" value="GIY41955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T6N7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11153" checksum="435C4FF49827D1FF" modified="2024-11-27" version="1">MIPLIVANFYLINPAKSKTGFILHLFCTTKQIYSSTKLPQKLRTAQSLWCLLFSNPFPPRIKGWRRSPGFRTRLVNECLPHLSAKHHPLNCDEESTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8P6</accession>
    <name>A0AAV4T8P6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_589701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010798">
        <property type="protein sequence ID" value="GIY42089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8P6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11328" checksum="1683E5FA314F73CC" modified="2024-11-27" version="1">MNSRDHETPGRREEMNKRRKERRKERKKKTQKRGTLKKKSSIAQQLHHYLGQEVNYEVVTPKAMETYFPLKDSIYRFHVLTARLGHGVPKVYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGS1</accession>
    <name>A0AAV4TGS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_667571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011132">
        <property type="protein sequence ID" value="GIY44356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9570" checksum="7BD98BBA4D295D66" modified="2024-11-27" version="1">MEGHSIDASQWKVHSIDASQWKATVLMRVNRTATSIDTSQWKSVLMRINGNAFVLMRVNQTINIDPRQWKATVLIRVNGKQQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIT3</accession>
    <name>A0AAV4TIT3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_506821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011395">
        <property type="protein sequence ID" value="GIY46290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIT3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11392" checksum="67857BD3661B8554" modified="2024-11-27" version="1">MLFKTTGRAQHVVVCPLELKFTYLQTDIERRVKEDERTLNVVAESHGDSFLLNAITQDETGKRLLGHPTGMIGGRLQAGGLFLFEARRAALRRHDLSTASRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8Z9</accession>
    <name>A0AAV4U8Z9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_437591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012488">
        <property type="protein sequence ID" value="GIY54246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8Z9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="19374" checksum="789E0D91BDE43725" modified="2024-11-27" version="1">MVKRKPKLALTRLDNGGQTAIRRCRLEETARAAPNFPYDTNPPSRFFPRQFLWQLTLHFCESTCFEEYGKISIPQAVTDLKTAASSLSFPSRGGWQPHSAELGASLHVMVKRKPKWVLTRLDNGDQTAIRRCRLERRRELLLIFLMTRTPYRISLRPFLWQLTTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UC94</accession>
    <name>A0AAV4UC94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_647761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012636">
        <property type="protein sequence ID" value="GIY55382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UC94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13610" checksum="0972334E5236521B" modified="2024-11-27" version="1">MIRTIPSRYFSQNHFIANRPVNDNDTNLTNHNRPPRRLVKDCFPILSAGKSLDYSSIRRLQTEWHQKLLPTEMRKKRLMKGELANIADEWTSFTENHRDCPAEEEIRRARYRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UD96</accession>
    <name>A0AAV4UD96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_212891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012673">
        <property type="protein sequence ID" value="GIY55779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UD96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11578" checksum="8803268406B0C93D" modified="2024-11-27" version="1">MSTKCYNGCKRLCVAFSFGLTSITSNYSYNTSPSQEGRQLCSTIQIKETDKTGHSSDNSNDIRVTFAFSNPHLSTAEIKRIYAAYILRCMMSIHTICYWCKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UG84</accession>
    <name>A0AAV4UG84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_145601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012815">
        <property type="protein sequence ID" value="GIY56823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UG84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11772" checksum="72788FA82103D90C" modified="2024-11-27" version="1">MWIYAISHSTILAFGVRSDGLTSKDILFRTSASGYDITPVSIPWTRTGLDRAKGREHLTRFPHSLVGSNRWCHNYILINDINSSHFFFETLSQDECLVATSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTF8</accession>
    <name>A0AAV4UTF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_266871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013427">
        <property type="protein sequence ID" value="GIY61082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UTF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9535" checksum="2FB7FDE5C18B579A" modified="2024-11-27" version="1">MCPPGKIAGDTPAEAERLRWLWRNGEIRTTNTTQQQNSARPKKATQAEKRSQKEGSRMMTGSFYLQNIFSPALLCKDSNGFSNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVR1</accession>
    <name>A0AAV4UVR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_347501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013563">
        <property type="protein sequence ID" value="GIY62001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="27031" checksum="624D5603A71834E2" modified="2024-11-27" version="1">MQNVEGNKDSNTVDFDCNRQCYKQVYQEMRKPNDLQNIMHNKSKKREIRKFDTKKYSFENEKNSGMFKMKHQKNAPDVLMEEDLSLDHLFGANVKTHFDHKCRNENLIQHEMQNVEGNKDSNTVDFDCNRQCYKQVYQEMRNPNDLQNIMHNKSKKREIRKFDTKKYSFENEKNSGMFKMKHQKNAPDVLMEKDLSLDHLFGANVKTHFDHKCRNENLIQHEMQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1D6</accession>
    <name>A0AAV4V1D6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_579621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013788">
        <property type="protein sequence ID" value="GIY63818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1D6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18903" checksum="5CE755E343F49F6D" modified="2024-11-27" version="1">MMVQKFLSRVASKFLTHEIRRRPKVPFTTSFRAFPYKRRYPFAVAQFLPRIVSVFLLFRFLFNQKLDSNLFIVCNHRFKPFTNAVLPGFLNRLQSINEFGSEGHTTMRFMNASSEDSNFGKSPSFITSTIPACQLNLNILDEYMFLPSTLERPPATLFKIRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VF55</accession>
    <name>A0AAV4VF55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MED14</name>
        <name evidence="5" type="ORF">CEXT_629181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014469">
        <property type="protein sequence ID" value="GIY68947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VF55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056877">
        <property type="entry name" value="Med14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055114">
        <property type="entry name" value="Med14_RM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055107">
        <property type="entry name" value="Med14_RM8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013947">
        <property type="entry name" value="Mediator_Med14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25069">
        <property type="entry name" value="Med14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22984">
        <property type="entry name" value="RM6_Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22983">
        <property type="entry name" value="RM8_Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator of RNA polymerase II transcription subunit 14 RM6" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator of RNA polymerase II transcription subunit 14 RM8" evidence="2">
        <location>
            <begin position="455"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator of RNA polymerase II transcription subunit 14 C-terminal" evidence="4">
        <location>
            <begin position="529"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY68947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="663" mass="72009" checksum="D72F5D7A9A9AFEE7" modified="2024-11-27" version="1">MMEIKSYTYKRLIIGYGLNKANMVNIYWNPGDKRYHLGFGIMGQTISASNPHTLASAQLQHEFNQHRSIMTLMQMLHETYAPLLSINKLPTITELGVVHSRPALPIQTFTTLVQTSTHYRVVYRNMYCLDIECRPEGFVAVRDGAYSVFDKQRAVEELSTISSIKAFLSKFVDETAAQARRRSQTEEDSNPLSPVPTLDSMDSGFLSVGSQVKPGSPAQPCRSQDGGLRFHLPMTPPSGSNPHTPASPHTSVLSQQGYGASPNPSFSLASPPSLGSQSQAHVSPSPSILQHVQAQSPSPSFLPTPSPSQVTMQSPAFMGQHGDAGSPFAAPASAGNLSMSSPAPGAWPGSPSVPRPSPRPTGTAQSPGSSSHPALHSPQAGTLADHTKAAGISSTSSRAHCSWQAGTPTLLTHKSFDQMCSPGPPTTGLMHTSPLERFLGCCYLRKSLHRMSSTSLEGGVTMFKAETLQCRVGLNPQTLQSLHLKLAPAPEYKDQWTQEELQVIERYFDTKVVSFPYKPNALQAFGRILNAPLRIFKDFIHIMHLEMVPDRSLKWAIQLCLTIPPGAPHCTPGHVSHCHDQGPHALLCAVTRIGLNLAPGVEPQSVVFSAVYDIKMNTTTVPDNRRDTMPMLPTDPVYIITNMLKRFAEYNPNLVSAATITNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNJ1</accession>
    <name>A0AAV4VNJ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LARS2</name>
        <name evidence="8" type="ORF">CEXT_167481</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01014803">
        <property type="protein sequence ID" value="GIY71401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY71401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11135" checksum="42CCAD60DAB87097" modified="2024-11-27" version="1">MLQFREPFIQLLMQGMVVGKSYRIKGSGKYITKEEVDFSGSTLVEKSSGSVVIEEWEKMSKSKYNGIDPQKIIEEHGIDTTACSYWEGYIRSLKKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPK2</accession>
    <name>A0AAV4VPK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_547271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014824">
        <property type="protein sequence ID" value="GIY71539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY71539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22395" checksum="DAC37ACD2E0D7B80" modified="2024-11-27" version="1">MSSSTSIVFKRPNSPLYLQKTYIVYVFVLGDKECGKSSLIRALTTKEVEDSNLPSLTVFQSRESVSQNVFQLRFCELSEETIHLEEVKRTCQQQNTVLFFCFAIDDAYSLHAINRDWIAPLRINIGIELPSILVGNKIDLRGHPSSSGKRLFKFSCGYKMRKVFDLRLYHECSSVSGKAIPDLFWLAVGLGLDPDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0C8</accession>
    <name>A0AAV4W0C8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pantetheinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Vnn1</name>
        <name evidence="4" type="ORF">CEXT_96381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015328">
        <property type="protein sequence ID" value="GIY75359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0C8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040154">
        <property type="entry name" value="Biotinidase/VNN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043957">
        <property type="entry name" value="Vanin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609">
        <property type="entry name" value="BIOTINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609:SF27">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19018">
        <property type="entry name" value="Vanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY75359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="562" mass="64198" checksum="B86950F52D12D6F0" modified="2024-11-27" version="1">MKRKDIIRSQALLFLILFVHSSCLFAKKDFYRAAVLELSQFTNISYPAADILRINLNIYDLAASTAAKHEADIIVFPESGLLPFEKPNREWLLDFIEDIPDPKKMLTNPCAEPDLFSDRPIITKLSCLARHNNIYVVANTADFKKCETDKNCDKDNSNCTVCPKDGHFFYNTNVVFNREGTLIAKYYKRHLYFEPEMNTPHKPEDAYFDTDFGNFSTFICFDLMFKEPVKAIGNLSVLNVAYPTYWFDHTPLIFFATPYQQAWAMANKVNLLAANGHHPQTGSLGSGIYSSSKGALIYTHNPDGRSKLLISNVPISPRDNTIDTNNLNPMRFFIENGTIVAAKGEEKPIFKKECLNTVLGDGKPGDYRCGPTNVDQYEFKKLQGNKGKITSCSNKLCCWLDYDSHSMDEDYYFGVSGKDLNFYDEFSFGTEACFIARCESYEGKSCTNFKLVSHTIFRKVEIRGNFTTKYILPFAIDSEMRLTNKDNWSFYESRIVYDNLNKKSSLLFFGVYGRLFEKDKDLYNQPDGAVRISCTGDWLIFGLLVSLSLFLFLKAYENGKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7E1</accession>
    <name>A0AAV4W7E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_156671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015717">
        <property type="protein sequence ID" value="GIY78114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11453" checksum="59640CB8C74FB960" modified="2024-11-27" version="1">MHSLDGTIEFANISIIYGAFSRHSSIVVLDHQYFTVLEFGSLPCPTHVGLSKTWWGCLTKEEFEQRCVNYIALGWSKYEIIIYKRDKTNDRRMTSTYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJ93</accession>
    <name>A0AAV4WJ93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tissue factor pathway inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TFPI</name>
        <name evidence="9" type="ORF">CEXT_237381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016204">
        <property type="protein sequence ID" value="GIY82051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJ93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000020">
        <property type="entry name" value="Collagen, type VI, alpha 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF374">
        <property type="entry name" value="BPTI_KUNITZ INHIBITOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043394303" evidence="7">
        <location>
            <begin position="18"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="8">
        <location>
            <begin position="22"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="8">
        <location>
            <begin position="81"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY82051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15539" checksum="73B855DFEC39EBD4" modified="2024-11-27" version="1">MYYVTVICVFLLNIIFATEDVCSLDPDIGGCSAYSQRYFFNRFTGQCHEFVFAGCLGNNNNFETIEECQEHCQGFELDKSCDKTKDKGPCEGYIWRYFYDNDLGECRSFVYGGCRGNTNNFSTKEQCAETCIPPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJS2</accession>
    <name>A0AAV4WJS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_101571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016303">
        <property type="protein sequence ID" value="GIY82902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="12325" checksum="037BD05A931F095D" modified="2024-11-27" version="1">MTADVRMWRRQAAVFKRNLLATNRKAFNNFIENINYKENNLKMYRFFSILSNKKLHLKNIRILFRDRDLFSDQRIEKLSHRHNVFRREKELTLGRHREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WKH2</accession>
    <name>A0AAV4WKH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_266801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016230">
        <property type="protein sequence ID" value="GIY82279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WKH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8597" checksum="A1F99C6B1C0E4D84" modified="2024-11-27" version="1">MPKDPKWWDREEKGLNLETEGGDVEGAWSECERRRDGIRDGRGCQKDCSGYRIAHRPSIGRTTRFLLIHVTRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLJ4</accession>
    <name>A0AAV4WLJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neurobeachin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rg</name>
        <name evidence="2" type="ORF">CEXT_266771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016230">
        <property type="protein sequence ID" value="GIY82275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050865">
        <property type="entry name" value="BEACH_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010508">
        <property type="entry name" value="NBEA-like_DUF1088"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743">
        <property type="entry name" value="BEIGE/BEACH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743:SF162">
        <property type="entry name" value="NEUROBEACHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06469">
        <property type="entry name" value="DUF1088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="1">
        <location>
            <begin position="159"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="26316" checksum="ED92C18B5559B802" modified="2024-11-27" version="1">MRADDVLKHADFESLCAQTVLDRKEEEKMCDHLITAARRRDSVTASRNIEKILNILTNKHGAWGNKISIPPREYLKLDSWEDDARRRKRFVQKILMVLVIQKLLSKQLLNMVLLRMQFCKHEEFHQHLAITRRQQQHHLQSSDLLDDSDLWDDKDLDAELAGPVSFSTKCRLIAPGVVVPGMLSITQAEMFFEVDEDDTEYKKMDPELRNISSYEVKDLLVKVAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WNR5</accession>
    <name>A0AAV4WNR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_676151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016531">
        <property type="protein sequence ID" value="GIY84565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WNR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12011" checksum="D47DE41F70DB8D3F" modified="2024-11-27" version="1">MYLEVLRRKEAPLSDILKGARTGAVAYYSFPFTDNISRNSTATPTPFPFLSPARTGKALSQLIQTSRHSEEEGCECPPPIKIPLPGSLGRAKTGALTNGGPADRPLYKRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQ53</accession>
    <name>A0AAV4WQ53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_469421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016461">
        <property type="protein sequence ID" value="GIY84046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQ53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15212" checksum="42F1EB756E6D1C0A" modified="2024-11-27" version="1">MLLAFQLGNLSARASKRTALSFPYLSEFELFQSLQGGWGWKKRTNAVKGFWLLWRCEVANVSRPALCRRKELKADILAHGSNEVAARAGSAWGLLFQLQGRKGWERRAEVWCWKQGVDRKPREFCAWQMPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRT0</accession>
    <name>A0AAV4WRT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-conjugating enzyme E2 35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">UBC35</name>
        <name evidence="2" type="ORF">CEXT_520381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016501">
        <property type="protein sequence ID" value="GIY84315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00195">
        <property type="entry name" value="UBCc_UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="27"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="18059" checksum="3BC3D4ED154C6AD8" modified="2024-11-27" version="1">MKKISLRDSAKKWSCSTCFATASGEKDDLYRILEDFRHIERELKNLLLKAVQSKLIKLVQNNLQEYDIYLVGPKGSAYAEQKFTVEMFLPESYPRVPPIVRFITKIKHPQIDQYGYIRNKYLGDKWSPSFGIPATLMILLELLREPCGDIRRESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVG2</accession>
    <name>A0AAV4WVG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_283521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016663">
        <property type="protein sequence ID" value="GIY85518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11645" checksum="1273BCBE72B5C697" modified="2024-11-27" version="1">MFPIDLIFAIDVSNDLCSVKPLFAAGEPTTPVAVVHLSRRQRMRQWCEGGFRGMTSIVILFSETLATSRRCPHSLPRVSEFKDPGEDYCRRGESILLGSPHIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXL0</accession>
    <name>A0AAV4WXL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_145371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016909">
        <property type="protein sequence ID" value="GIY87206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11182" checksum="88249498699CAAB5" modified="2024-11-27" version="1">MSIHAGVSSMMEMEVSPYDSQSPFQVRLSPAAPEQHQQTQSPDAICSTLQSIESEISNDQEELASYQIYASLKTTQQTPGMRDSFQSDMELVERKISTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X021</accession>
    <name>A0AAV4X021_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_319471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016926">
        <property type="protein sequence ID" value="GIY87344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X021"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="15404" checksum="6029140862D4CF5E" modified="2024-11-27" version="1">MACPNTTYTSSLKNLRRSRKLFASPITRPVTPRLAAAPRPLCVRPTFVDYGFFFLFFLLFFFFFREQTGQKPRPTSRRMGKALRGRRRSSAIMVAVFRQFLDKKRRKPSPPFLTWSVVQILLFSLHARTVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1X7</accession>
    <name>A0AAV4X1X7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab effector Noc2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_15835</name>
        <name evidence="2" type="ORF">CEXT_227811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016981">
        <property type="protein sequence ID" value="GIY87814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1X7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="424" mass="47597" checksum="1C474EDB4193E916" modified="2024-11-27" version="1">MKLFQLGVIVPDSPAPDVTLAAGHLQKIAFPLHALLSCSGQVVAAIDEQGGRQFFVPAEGRHHGGLRGGRPRQVGLPQRQGAIAQGQVEDGVVREDEFHQLLQQARAAERRGAGDHHVRHQEGREPGQNRAGTCRASGGTTGEHEETCDGKREQPVRPVRGGVRHSERIPPVLLRLQKGCLQETWKKSGAWFYKGLPKYILPVRHHEPSKYSTTASPSKSGEQTQSPQRSYNSWLQSKGKNTSEKENTDSSDDELKSSRLAKRATVKKSYGESVENHDYGGAMTPPTDFTQGPSPTHLYSPNIPDSPRSPQQRDDFNRSPQHEGYLPYAKQEKRVAEGERSQTPTATASHWYKPSTRRDEPEDYPDRQYRGHSRKDPQDSPVRYRPPSSNSRAEEFSPKKAPSPEETSKKHRRFYKKRKHRKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4M0</accession>
    <name>A0AAV4X4M0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_210264_1</name>
        <name evidence="1" type="ORF">CEXT_519911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017296">
        <property type="protein sequence ID" value="GIY90142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4M0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="15492" checksum="DEF750DC17920341" modified="2024-11-27" version="1">MSKLKKDPSAFLLAAAIPISILLAAILPALMNNMVAIPTVSTIVTGSKARKFIENQFISPIIDGISTFGARALEDPGCIQRTFCEVTNESSSNHRDSRILQRVLHKASTFVDDKTLDNYGVKNCSNLCLMEIVKKCPAQILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5Z5</accession>
    <name>A0AAV4X5Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_232491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017308">
        <property type="protein sequence ID" value="GIY90266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY90266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="19233" checksum="05B3F9B96BF43EE4" modified="2024-11-27" version="1">MQPTVEEYHDFVTITCSSTSHFSADVTYLAAVDLRRSPKLTDPLAFSADLCVYELAKYLAWVMDMAKHEFYFPNNSLVYCLFLINAELFVVCWRRCEMCWRDNLSKSERRLMLFPSHRPPVVDSSVCGNTPSPAQMLQREREKSIFCETTDFTFRSGRSVRSSDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X6V1</accession>
    <name>A0AAV4X6V1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_88741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017365">
        <property type="protein sequence ID" value="GIY90972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X6V1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9395" checksum="1E27EBB25A5B5090" modified="2024-11-27" version="1">MSLASVDLAVDGGRNEREQLEHKEASTQQKGRFRTKINVRKNTGTTFFQDGWRKSSFKDLSFWFGRQRVRLYQTFRLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X843</accession>
    <name>A0AAV4X843_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_54831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017411">
        <property type="protein sequence ID" value="GIY91407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X843"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13423" checksum="95577D32DF38E6CD" modified="2024-11-27" version="1">MGSFPKNSRLLNIQIVAEIAQFMLLIAEMSSVSSRDSVMNSLCEYRLLLTSPPSFPQSPDRVRKHLSAPVEAPVERTLVYRLQRTGSVGRWAVSERARRSCCTWKKKGLRERSFFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XA28</accession>
    <name>A0AAV4XA28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_475461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017483">
        <property type="protein sequence ID" value="GIY92002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XA28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12834" checksum="E328BF48B6A9FD1F" modified="2024-11-27" version="1">MAHVLTTWFNLKFEFVFEIESWYNRAHRAHVRITWYNRAHVRGTNHVVHVRRAHVRITWYNRGSCSNHVVQPSSCSNHVVQPSSCSNHVVQPNSCSNHVVQLNACSNHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBB4</accession>
    <name>A0AAV4XBB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinesin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">KIF12_2</name>
        <name evidence="2" type="ORF">CEXT_685791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017383">
        <property type="protein sequence ID" value="GIY91113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="28505" checksum="CE574DE2A3E052FB" modified="2024-11-27" version="1">MENSFLRQQLHLDNGLLTNNKGAAAVRGNIMMDDMKPDELKAMLQQYMNDNESLREENAELRFTNDLLTRELERVNKENERLQKERTRSARQTRRPDSITASRAVLGSSDSLIDSNTWNNGAWRSIIDVDGEIELMNNLNNNSTNMNGRATLNRQTQQLTPAKRKVGKSLGDITENQDECEEKQPVGLRRQRRNSWGSGIPRPVDNRSSKSPPQNTPSDADAEEMFEDRITPESNPTTPGSKLPPLPINAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XES2</accession>
    <name>A0AAV4XES2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_142031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000143">
        <property type="protein sequence ID" value="GIY92461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XES2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="14135" checksum="75569E39768EEEFC" modified="2024-11-27" version="1">MRLWTKFRFFHVTSRLSMAVNAKTLQVLQFYWFLLWHDGFGDSIEFPNFHVLPYAVFNRTIRDHILHNVQFSNTHQFITFLYSTGKHLTYSADGNKPLVWMQVQGHQDVRKVNHNHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFP5</accession>
    <name>A0AAV4XFP5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_215591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000341">
        <property type="protein sequence ID" value="GIY94027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="24274" checksum="AE55F7EC8F496F60" modified="2024-11-27" version="1">MVKFKCGCTGICDKSCPGLPNKVPIPEKIAKIPDIFIFSLSLNRFTILTKKELTLAILTKKGDPSPAVRWLRNAELLDDSYYITLKDSPVTNCYYPVSREPTSCPVSPVRCPTQTCPHPSPAPEAYRCSHHHFTCRDISVRQPFEIVCVAKREPDHPHKCPGGWMAKSSPPGSQRALRGRRTSLPAVLFSIPANTTIRGTCPVGVTTSQLPDSVLRTLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKH3</accession>
    <name>A0AAV4XKH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_421101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000486">
        <property type="protein sequence ID" value="GIY95184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9976" checksum="94C96092F7FD91CD" modified="2024-11-27" version="1">MSIHAGVSSMMEMEVSPDDSQSFRADCHQPLLNNISNLNLGAICSTLQSIESEILSYQEEFATYQICARLKSTQQTPGLMDLFQSAMELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLA5</accession>
    <name>A0AAV4XLA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_635881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000470">
        <property type="protein sequence ID" value="GIY95000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12063" checksum="92A0D76705F668E3" modified="2024-11-27" version="1">MTEISQKTNTTFKSFLIKSKGRNPVLSSRRKKIPVSPDIGFQLTIFIAAFPDNFAAALNKIPKDPRCELFYFFFYPFSSSSSSGMVLLSLLAAPDLKVEKFMAASEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMG2</accession>
    <name>A0AAV4XMG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_738511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017936">
        <property type="protein sequence ID" value="GIY95573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15898" checksum="E25A2B7E9124C018" modified="2024-11-27" version="1">MANLNPVALLDALHSSLYRFLNGYRENRHHLVTPSALRDSLKTRSLLKYGIDHHSFRPWAFGDTRPLRQQENCSAIPDHFTPTTSKSTGVLSRASLAERFPVSAAPLTEHLPVLEHPSFVGAPQMLNMIQDKHHPPHIPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XML5</accession>
    <name>A0AAV4XML5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_79591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000592">
        <property type="protein sequence ID" value="GIY95919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XML5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8705" checksum="4CF93BE29B5A82AB" modified="2024-11-27" version="1">MSSPDLQPSDLTKLTENGNFKRNVMDFFRLYPSNDWSRRAKGGKKYEPLCFLNNDIQSLMLQWDGTENWTSIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQL9</accession>
    <name>A0AAV4XQL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein ROP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Rop</name>
        <name evidence="8" type="ORF">CEXT_609041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000785">
        <property type="protein sequence ID" value="GIY97476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051650">
        <property type="term" value="P:establishment of vesicle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.60:FF:000001">
        <property type="entry name" value="syntaxin-binding protein 1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2060:FF:000001">
        <property type="entry name" value="syntaxin-binding protein 1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.830.10:FF:000001">
        <property type="entry name" value="syntaxin-binding protein 1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY97476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="587" mass="67194" checksum="12B1927096FD02F2" modified="2024-11-27" version="1">MALKGVVGAKIMNDVIKAVKKKGDWKVLVVDKLGMRMISACCKMHRIAQEGITIVEDIEKIREPLPNMEAIYLITPTDKSVERLMRDFQVNRNMYRAAHIFFTEACGDELFNELCKSPTAKYIKTLKEINIAFLPYESQVYSLDYPETFSLYFNPSKTSQTVNLERIAEQIATVCATLGEYPNIRYRYDFDRNVELAQLIQQKLDAYKADEPTMGESPEKMRSQLLILDRGFDCVSPLLHELTFQAMAYDLLPIQNDVYKFETSTGPDVNMKEKEVLLDENDDLWVELRHQHIAIVSTSVTKQLKTFIESKRMTASTDKASFKDLSVMIKKMPQYQKELSKYSTYLHLAEDCMKCYQGNVDKLCKVEQDLAMGTDAEGEKIKDPMRNIVPILLDGAVSTFDKIRIILLYILSKNGITEENLAKLIQHAQIPPTEKAMITNMAMLGVNIVTDGSRKKPYQVPRKERITEQTYQMSRWTPVIKDVMEDAIDDKLDAKHFPFLAGRVAQSSYGRPTPTSVRYGHWHKDKNAPNIKNLPRLMVFVVGGACYSELRSAYEVTKEYKNWEVIIGSDHLLTPEGFLTDLRDLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR71</accession>
    <name>A0AAV4XR71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_430361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000647">
        <property type="protein sequence ID" value="GIY96334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12454" checksum="3F264791872775D6" modified="2024-11-27" version="1">MLLAEQQFMLQTQLLISRPDIHDFLSSDLLTFLLTFPKLPLSHICSVDAGNELKTRYCGNSSNVCSVEHTAPLGRSFGAISGKHGPESVTCCAAVHASDTTAHFTPLHSRLSWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSJ8</accession>
    <name>A0AAV4XSJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_622981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000868">
        <property type="protein sequence ID" value="GIY98007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14409" checksum="570E1AE227EC6484" modified="2024-11-27" version="1">MVLKTRFSLIRYGCLKLGEGFAYSSVKDGFPKTIAAYVYDHPNAYSTAYRVAYFTGPYIPKSKMPFATLAELHFEHPTTPKIAAVAISDLIKCQGKSQAPISLHHHNPNPQIYMHTRTGESYRPPYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWJ5</accession>
    <name>A0AAV4XWJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_263311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000904">
        <property type="protein sequence ID" value="GIY98254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="60" mass="6826" checksum="B2382D111159D393" modified="2024-11-27" version="1" fragment="single">WITEDSMVVAGDVCADERYACFSKTLPFISVSVRYVKSHRLRYSDISHSNELTRCLRGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXP3</accession>
    <name>A0AAV4XXP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MAM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_19602</name>
        <name evidence="2" type="ORF">CEXT_609601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018409">
        <property type="protein sequence ID" value="GIY99313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAM" evidence="1">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7599" checksum="E51FA09C896251D3" modified="2024-11-27" version="1">MATKKFDTSRPDWMYGQVSVATLTAYRVEFEGEATDGGFALDDVTFYDGNCQTRPERAAVEPPPSEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY73</accession>
    <name>A0AAV4XY73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_490451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018343">
        <property type="protein sequence ID" value="GIY98824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12187" checksum="2EDFC0E49CC60DA6" modified="2024-11-27" version="1">MPKHDVPNFCNQKRNIEQILQVGTSFFTIRSSPLGKKRIRIAGSTEDKNPRLESSKLEHHFSLYAQVLLRKKTRIRIAGRKSKTGVYPDVQDRTDVINCEGKDYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y228</accession>
    <name>A0AAV4Y228_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_281491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018516">
        <property type="protein sequence ID" value="GIZ00205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y228"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18536" checksum="A089087B2A02CED8" modified="2024-11-27" version="1">MSFHFGIDFFSRLKSQVPERMPSRGLTTNMHDWATKETRHSPNARRLTSRVVLKGHEMATKDEKADGKSETSDLYSLGNSSSQRNQIFPQIFTALSKLPNPWERTIRMDDQIPERHAMSSSLSGTALLIKFRSPENRTGGKHTPRFRWPLSADPLEQSTFEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3J6</accession>
    <name>A0AAV4Y3J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dscam17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_268581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018613">
        <property type="protein sequence ID" value="GIZ01010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12424" checksum="E92A248BD6A0832A" modified="2024-11-27" version="1">MQNGESLPNSHRHEVRPNGKIVIHYVEKNTDDGTYWCTAGNNRGVSARGRIDVHVVAGPVLDPFNFPENLREGRRTTLTCIVSAGDPQSPSDGKRMANPYNLLYWMSPWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3W7</accession>
    <name>A0AAV4Y3W7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial ornithine transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Slc25a15</name>
        <name evidence="11" type="ORF">CEXT_619261</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001260">
        <property type="protein sequence ID" value="GIZ01145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3W7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="167"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIZ01145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="282" mass="30906" checksum="21BBB2183C8D841E" modified="2024-11-27" version="1">MKDFVGLSLCDSEIGGAACVFVGQPLDTIKVKMQTFPNLYKNSFICFKETLVKEGFRGLYAGTVPALAANIAENSVLFCAYGVCQNAVKFLIKKDDVLDLNPLENATAGFFAAFFSSFSLCPTELIKCRLQAMRETSCNDVHNRTNIGPWSLTKEIFRTEGKSKDEIGLFRTIIAGGIGGVSFWVAIFPADVIKSRLQISKTNDSTIEVTKQLIRKDGFRALYKGLGPTVLRTFPASGALFVAQDQIGLVDSALGFWIRVDGFKTLLVMHRQKSVAGIRGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9N5</accession>
    <name>A0AAV4Y9N5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_106861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018928">
        <property type="protein sequence ID" value="GIZ03269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12920" checksum="C7FD8040BE406BAB" modified="2024-11-27" version="1">MGIPRTCLHKSNDLSLQFPRITSESPEPSSCIIHPSPKHKILVNARAEGTKKGLQHTGRSRCMWAKVERPPHHHDRDISCCCPGSICIMHMAGASKAPSIFAAYPWCRKRHEDASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9V6</accession>
    <name>A0AAV4Y9V6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphatidylinositol 3-kinase regulatory subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PIK3R1</name>
        <name evidence="9" type="ORF">CEXT_131101</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001592">
        <property type="protein sequence ID" value="GIZ03344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9V6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20830">
        <property type="entry name" value="C1_PIK3R-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12923">
        <property type="entry name" value="iSH2_PI3K_IA_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000006">
        <property type="entry name" value="Phosphatidylinositol 3-kinase regulatory subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000146">
        <property type="entry name" value="Phosphatidylinositol 3-kinase regulatory subunit alpha-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032498">
        <property type="entry name" value="PI3K_P85_iSH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051854">
        <property type="entry name" value="Rho-type_GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075">
        <property type="entry name" value="CHIMERIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46075:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16454">
        <property type="entry name" value="PI3K_P85_iSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00678">
        <property type="entry name" value="PI3KINASEP85"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SAM" evidence="7">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="6">
        <location>
            <begin position="112"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="8">
        <location>
            <begin position="182"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="5">
        <location>
            <begin position="404"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="5">
        <location>
            <begin position="697"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIZ03344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="804" mass="92315" checksum="6A962198ABAF8C0B" modified="2024-11-27" version="1">MNHSFARQTIQPNLSGVPLSQWTSSNVVEWMAALNLYRYAELFKSKDIKGSDLMTLDRDKLMNMGVKDEFHQKAILVCVDDLCQRNNLNRSLHETKVQIATLREGSSPTGNNHQLLEQSFSCVLQCDKCHNYLHGVIHQGVVCQECGLIWHRTCAATGLPRCNTENLEKANRRSLISAIFGKDLSCQFLPSVQSAPLLVMRCIFEIESRGAATNSIDLYRVYRTSAPSDIVAELRQKLSEDVERTNLASYELHCIASALKKYLRELPNPVFPVQFYDKFIEIAKIQNDDQCVQALEQLVHQLPIHHKSTLQTLMAHFCRVCQLQYSRGIKEPPTILIQMLCHILLRPPWERIVQIVYNTEAHIRVVELLLLKGKWGEPMPVFDSAPALPPRRISKINQPFPDSIIHSNMSPNNSEEVNEKLKDTPDGTFLVRDASNKGSGEYTLTLRKGGSNKLIKICHRNNKYGFTEPLMFNSVVELINYYHNVSLAQYNRTLDVKLLNPVSRFHPTGMDEDESIDVEKVGEKLMKINQEYLQKTKLYDQFYEDYSKTFQDVQLKKQAQDAFTATLAVFEEQIHLLEDNLKGAAPCEIQPLMENYELLKSRLQVLEESKKQLDMELKYQAAFHRSLDREMNTLKPEIMRLYKQREDFQAMLYAKGVKKDRVFKLLQDSCTEARDIIRESAFLQDDETLPHHNETLWFLQDISRNEAVRLLTGKPDGTFLIRNSRTQGQYALSIVADGKVGHCLIYKTEKGYGFAEPYNVHPSLKSLVLHYAQTSLEEHNDTLKTTLAYPVFSLDHYVTQSTNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAC9</accession>
    <name>A0AAV4YAC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_456711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019022">
        <property type="protein sequence ID" value="GIZ04005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13393" checksum="CA9B94F2B559C531" modified="2024-11-27" version="1">MLISQSSTVLLSPLQPEASMVFVRRKPFAKESLHYTFLEYSDFGRYLPNSGDGYHVHFCRSHGGGPELPLPWSQQKGGAFLPQGTLPQEVRLLLLLQLTQEGQAHNLRGRRPPARPLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAH7</accession>
    <name>A0AAV4YAH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_237491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001689">
        <property type="protein sequence ID" value="GIZ04065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="43" mass="4670" checksum="1609C6AF053B610D" modified="2024-11-27" version="1" fragment="single">MQLRNGKISILDPSASNTEEHPEAHSMLVERSSGCVKKSAMAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBF1</accession>
    <name>A0AAV4YBF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_41971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001774">
        <property type="protein sequence ID" value="GIZ04648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="18" mass="1906" checksum="1B9A6E7940274FC3" modified="2024-11-27" version="1" fragment="single">MIKVMSLSPASRLDGFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCR8</accession>
    <name>A0AAV4YCR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_471241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FARP (FMRFamide related peptide) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019251">
        <property type="protein sequence ID" value="GIZ05251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002544">
        <property type="entry name" value="FMRFamid-related_peptide-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051041">
        <property type="entry name" value="FMRFamide-related_np"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20986">
        <property type="entry name" value="FMRFAMIDE-RELATED PEPTIDES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20986:SF22">
        <property type="entry name" value="FMRFAMIDE-RELATED PEPTIDES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01581">
        <property type="entry name" value="FARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0027">Amidation</keyword>
    <keyword evidence="6" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ05251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13492" checksum="1372D24024FB9327" modified="2024-11-27" version="1">MHFGKRSYPWELHNTMHFGKRSDDWESHNTLHFGKKSNPWESHNTMHFGKKSDPWEFHNNMHFGKKSYPWENHNTMHFGKKSDPWKLHNTMHFGKRSDPWETITLYILGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDT9</accession>
    <name>A0AAV4YDT9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_170211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019078">
        <property type="protein sequence ID" value="GIZ04389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDT9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="984" mass="111541" checksum="DB48002F7589D0FE" modified="2024-11-27" version="1">MDFSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDFSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDFSRICSRQHTFDIVENNEVSISTGDMDFSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDFSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDFSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDNINMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEISISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLCRICSRQHTFDIVENNEVSISTGDMDLCRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLCRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLCRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDFSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVENNEVSISTGDMDLSRICSRQHTFDIVQNNEVSISTGDMDLSRICSRQHTFDNVQNNEVLISTGDAPLPNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE76</accession>
    <name>A0AAV4YE76_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_290471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019237">
        <property type="protein sequence ID" value="GIZ05224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30169" checksum="C770E1E96BC3D1A6" modified="2024-11-27" version="1">MHPFKGCSSYDAICPVKRQVLKLTVGSETEHIRLKNKLVQLGLEFKCFNLKQDRPLKILIRGLPSCTSKEAIGSAINALENPTPKVEKKAQRVPPKNTTTYGKPIPAPQPRTQPPVSNRRFADVTAGRAQNLTPPTEAPLNKSAMEFFKLLLAYIDDESIDFDQLLEAVRLALPSLSTITDHHEKAVTLLRFYNIVRKITINMFPLNSINLHSLRIGYWNANGIRRQLQEVKEFVSDHDLDLFLIQETFLHPGLNPQIPNFTLQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD39</accession>
    <name>A0AAV4MD39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nrf-6_9</name>
        <name evidence="4" type="ORF">CEXT_560491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019648">
        <property type="protein sequence ID" value="GIX70082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006621">
        <property type="entry name" value="Nose-resist-to-fluoxetine_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF12">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20146">
        <property type="entry name" value="NRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Nose resistant-to-fluoxetine protein N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX70082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="504" mass="56150" checksum="0CCAFF4FDDAF5949" modified="2024-11-27" version="1">MSGNFNWVGSFNECRNVSVPVLKNTTQGGFNGQYCQLSINLLPDSYNFPLKLGTCLPNTCDSSNLITILNTIMHKRRAMRAKRQLENYLVPKKFQSFFPESFVSTSKTVELKCFPESREFSYGTIVYISVVLVVAACCLIGATITLCSRQPIKEKDCCDLKEMSVPKTNNIEMSSLPNIENNGDSINGTSEDSSISGSNSEGECVVTNEVRRVEDGPQVEEEKQDSATSSNNSEGECSATNKDRCAEDVPQVQENKQDSAISDSNSEGECNVTNEVRCVENVSQVEEEKKGVKNFLKKFFLCFCPITNEEKMQLTAQSQRPVLNGLRSFAAAWVLLCHTFSFAFNVVGNPVEALSMADNLWYQVILNGFYSVDIFFLLRSSNKGGTHRAMLNLSQICASTSVRIYDFLFVTSFRHLASGPFWPHDTGTCQDNWWMNLLFCEQLVYRGSSGGFLRHGRSNSCSCPPLHLWTLSVRKGHLPHRGLFLQLVASPAVLSLRSMVPVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD66</accession>
    <name>A0AAV4MD66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_639591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002112">
        <property type="protein sequence ID" value="GIX70112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12819" checksum="6A770675AFA2B82D" modified="2024-11-27" version="1">MPSSRVNDNLNDCREKKRKQKSPCKTTVRRSIQSGAQTCRREKERKTYALGKSRLKSGVCNLILDGPCPTDPMTRQTTFAFLLPPFTLWSASPEDAYLCISNTYRQYISPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIU0</accession>
    <name>A0AAV4MIU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_139381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019694">
        <property type="protein sequence ID" value="GIX70709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10272" checksum="3DE589594E796527" modified="2024-11-27" version="1" fragment="single">LAESEEREKATPERSRREKSDKNLYPVSSGCLFRPTEACPLAVINRMRQRAFVPCDYCVDLAVKLTSSPFRSVPSCFSFRLLQSVCSLAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMF8</accession>
    <name>A0AAV4MMF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">H15 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_249809_1</name>
        <name evidence="2" type="ORF">CEXT_422971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002421">
        <property type="protein sequence ID" value="GIX73525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="1">
        <location>
            <begin position="38"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="18945" checksum="2604B0408296BD63" modified="2024-11-27" version="1">MNSKTKVPLKLDLNDSRNRIFAFALSRNESTVKKKIVISAIDKDLKGASISGIVNWILSNYVILDPKKLKISVKKAVLKGLKGGTIKRSQGSKSAQGVIGSFTIPAKEDVPKKVLKNPRKSLIPVSITKDDSFIEKSKKDTNRKVSVIPKDKVRTEKHLARILPRKIVGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMG8</accession>
    <name>A0AAV4MMG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_316181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019911">
        <property type="protein sequence ID" value="GIX73095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10038" checksum="76E2394A6D5D5889" modified="2024-11-27" version="1">MIDGGDLSSRSNEPFILFEKHNFKDLTTSSRKKKSLILLGSTEELGCEADCIPEIVATLLFSACHLTGDMHHSETSPRASMWRNVSFLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQ91</accession>
    <name>A0AAV4MQ91_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_194451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002363">
        <property type="protein sequence ID" value="GIX72989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQ91"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15519" checksum="3B1E4CE06449E7D8" modified="2024-11-27" version="1">MGKKLMYLAGDKERERDITVVDDGKKPDFFIPVEDYVQEITVFRKVSSATFMIQPGPFIPIQNQTRNGRSNPARPVKCPDPHPPIARHLQVAIIFTLCGLMYLWRLLAVTKKRFPMLKRRSARYKNNHIFYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQQ9</accession>
    <name>A0AAV4MQQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pantetheinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VNN1</name>
        <name evidence="4" type="ORF">CEXT_479931</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002522">
        <property type="protein sequence ID" value="GIX74708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040154">
        <property type="entry name" value="Biotinidase/VNN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043957">
        <property type="entry name" value="Vanin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609">
        <property type="entry name" value="BIOTINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609:SF27">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19018">
        <property type="entry name" value="Vanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="56"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX74708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="454" mass="51288" checksum="3C61F7E99F0322BA" modified="2024-11-27" version="1">MAPPGLESETCGTERQSARLSPFRPELKMKNDFSLVLFERVSPGNSLRQGLLHCRCGADIILFNEYGTYLTRSRERLLSYAEYVPDPRIQKFNPCTENAKNGHVLYTLSCLARENNIYIVANLVSMQSCDSTCDADQIDSCEFNCPEDGVFFYNTDVAFDREGNVVARYRKVHPYFEIVNAPEEPEFAIFETDFGKFGMIVCFDLVFEEAVLLVEEHGIDTLLFPTYWFDDIVVLNAVEFQQSWAITNGVNLLAANTHAPGSGSLGSGIYSRADGALVYTYEPDGKSKLLIANLPIKNNSKIPDISSMTEIVPDDAIPKIETGEKFPENSYEKSAGPAIDNYADYRYFKSQFENYTLTKLEKPSGEIQACRNEFCCSLAYSTQNLQEDFYLAAYNGLNDVKNYFQWYEEVCILTRCDPLDGKPCVLQPLTSKTVFQAVELKGNFKAKEYILLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MS80</accession>
    <name>A0AAV4MS80_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF229 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_08788</name>
        <name evidence="2" type="ORF">CEXT_525441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002437">
        <property type="protein sequence ID" value="GIX73694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MS80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16021">
        <property type="entry name" value="ALP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000017">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004245">
        <property type="entry name" value="DUF229"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974:SF1">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02995">
        <property type="entry name" value="DUF229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="591" mass="67077" checksum="060B67A6D30BAD66" modified="2024-11-27" version="1">MFRRIPSRRAVLKGILVVDLLLLPFLFLLLSRWNTPPTFIAEHPYFLYDLDLKEPRSSGQKCVLPKLHPFDPSIWNYFSPPKDIVCKTRQLDLTFVSKEGILTFNGTQLELSGYEVGRNLHCHWYTVLRAGDNQDDDDKVVYRSEAVLPSNGTFLPHDQEVFQVKCHNFAGITVYERLHARVRNVTRPDGAKDSLKNPVNVLIFGLDSLSRLAFIRLLPRTYKYLTEDLQMTVFRGMNKVGDNTYPNLIALLTGRKAYGGGLPDYNLGYDEWPLVWKNYSEAGYDTMWAEDFPQYGLFNYLAKGFRRPPTDHYLRPFWLALEESSLLKFSSHMCYGPHPKHILQMEYVREFVAKYNSSRRPYFAFSFLAELSHEYLSRVASADDQFEEFFRFLHQGGYLQNTILIVMSDHGHRFDAIRATAVGHIEERMPFFAIHVPQNISSTQSEVTTALNLNSARLVTPFDTHATLIDILNFSAEGHPLGKTLPPPGTLGQSLFREVPLERTCENASIPINYCTCETESPIPDSDTRAVLAATAIIKHINELLKDGGTTITEGCASLSLKVIRTAHLVKTTEDFGDTGLKSQGCCGGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTC7</accession>
    <name>A0AAV4MTC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_25101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002560">
        <property type="protein sequence ID" value="GIX75109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12083" checksum="2525665668D12630" modified="2024-11-27" version="1">MPSPISTHEKNPGKQMSICAENDAAKFPSDFRDHLVENVAIIKQITSARLSKMRLATFKAASHWWRHPAVVLTSCDVRVESRIAVFIMLTLYLYFSFAIRTFLALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZB3</accession>
    <name>A0AAV4MZB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">FMRFamide-activated amiloride-sensitive sodium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FANA_0</name>
        <name evidence="14" type="ORF">CEXT_633221</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020296">
        <property type="protein sequence ID" value="GIX77045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX77045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="42697" checksum="1E2712BF5F1639FB" modified="2024-11-27" version="1">MKRRNPQNQKNYSELTNSFFKKSSIYALNQIGNSNTIRRKVFWAFILIGGLVGCCSQVYRYLSAYYGYPVVINIDSVNYFNQIFPGVTICNLNSVRIQYLNCVIQRRDYENCKSDKYIGPDNLTAAVSWSSPYCFEEEGTTLSDEFVERIQFMSLYFSLDEISRFMYGHQSEQFIQSCSFNGEECSHEDFTPHPDNIYGNCFTFNKANETKNPLKTSFVGPNSGLTLELNVESEEYSWLTKSVGARVVIHDPYQEPTPEDQGINVSPGFETVLGLSRVAMNRLPYPYKDRCQNYEKGISKRHCDMTCNRKKISRFCDCSIPYSTLESGRYCNYNNITELCCVYQAQKEEGLEQKYNLILRLSSGMRTCEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCU3</accession>
    <name>A0AAV4NCU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_413651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003215">
        <property type="protein sequence ID" value="GIX82189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7409" checksum="055508D08FFE5F5F" modified="2024-11-27" version="1" fragment="single">MECVNLLFQGRPVSQIQLAIPRVAVSFLSNMECVNLLGQGRPVSQIPLAKYARVTVSFLSNMECVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE47</accession>
    <name>A0AAV4NE47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA topoisomerase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_10808</name>
        <name evidence="2" type="ORF">CEXT_357751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020832">
        <property type="protein sequence ID" value="GIX83092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA topoisomerase I DNA binding eukaryotic-type" evidence="1">
        <location>
            <begin position="45"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12488" checksum="1181E594A5494EE4" modified="2024-11-27" version="1">MEEAMEVTEVAMKVNKEQIAVKRKRSMTQVLQKEWEEQKVGGGIKSQTLSHNGRIFAPDYERVSHHVKFYYSGKPMQLSKKAEVVAGFYGRMLDPEYTSKSTIKQEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEE6</accession>
    <name>A0AAV4NEE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_408181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003301">
        <property type="protein sequence ID" value="GIX83199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11272" checksum="2AC82764785BEB0D" modified="2024-11-27" version="1">MALDELSIVKPRQSSPVSGKKMISKEIERPGGIARLVAVAALAFCSQIDPLQITGVVSFLLQLFYTFAASIVRVGTPRGAIPHNWSQTNSTSKPVELDRLLFCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIK0</accession>
    <name>A0AAV4NIK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_278851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003317">
        <property type="protein sequence ID" value="GIX83294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="10084" checksum="8261A53DF662A009" modified="2024-11-27" version="1">MKKKKDTREKSWRKKKKKKARKSRRLDGVVMGGRVIKTRWVLGLTFHRRRREQLRPDDNSAVKERFNDFKLTRMALLRTEMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMU9</accession>
    <name>A0AAV4NMU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_376611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003566">
        <property type="protein sequence ID" value="GIX86132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9062" checksum="55CE5B3C394CE8CC" modified="2024-11-27" version="1">MDGKLSSNRARKEKRNTANGFRSIFFRRQPIDYGNKPNILITQLCFFLPRIIPRAETNGGSLSRTPAIRDRKSNNPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ24</accession>
    <name>A0AAV4NQ24_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CHST1</name>
        <name evidence="3" type="ORF">CEXT_227941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003597">
        <property type="protein sequence ID" value="GIX86509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="2">
        <location>
            <begin position="156"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX86509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="541" mass="61498" checksum="429161A763FF9E6D" modified="2024-11-27" version="1">MNTLFGSCVSSVEGLGVPTNVCGGGVIENTHDAGPNSSATQQASTAQIVIQSTSLRPTVAQSPPVQQKSVDRTVRTSESPKQTPAHILVNKTDRVEAKVQVRRLPLAKQVSGAGTISRQDRLHEILKQSSVIHRRATLDPMRSLKSIPLTNPEKVTRIIILTYFRAGSSFFGDILQQNWKTFYHFEPLHFMTYDKRIDDDKLPEVFNLFNNIMGCNFTESREYMQWVQKPRNQFLFAHNLFLWVTCHSNPKVCFSPAFVNAVCTRAPIHVMKTTRLHMRQLRSYIQDNPNMNIKVIHLTRDPRGIVSSRWSLDWCNGTNCSDAGVLCKEMDEDIRIFEDLQKENPSNFIKVRYEDLSLNPLNETEKLFGFLKLPFSTSVKKFLKTHTVGRKSDAKNPYSTRRNSSSMVNSWHERFSYKQIVDVQSQCGDVLHSLNHSLITSPSQLPYPNGKPKPKVTAESSRSKTWRYNKNPLAKKYFANKGEFAQDSAVPAPSFTSNRSEIFRSNNTNIEVHKSYKFLKDFSAKNSSIKPSLTPLNKTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWG2</accession>
    <name>A0AAV4NWG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol-binding clathrin assembly protein LAP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lap</name>
        <name evidence="3" type="ORF">CEXT_176091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021410">
        <property type="protein sequence ID" value="GIX89257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098894">
        <property type="term" value="C:extrinsic component of presynaptic endocytic zone membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008021">
        <property type="term" value="C:synaptic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016185">
        <property type="term" value="P:synaptic vesicle budding from presynaptic endocytic zone membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP180 N-terminal homology (ANTH)" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX89257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="833" mass="86060" checksum="0411455AECF2868E" modified="2024-11-27" version="1">MNKKHARDALDIYKKFLIRMDRVAEFLKVAENIGIDKGDIPDLTKIARRCGNLPIFSSKHAPSSLLEALEQHLATLEGRKGSTSAASAAARATNLQNAVNALSHTSHAFSSAGENSPQQEMNGVKIDESVRKAVEEEAEIMNQLKFDNDSPLLWEQPAWEDSERRLKEMTSSGDIISPPAGSTKTNPFLSSPEPTAGTTPSANQRIMDLFNTSTEPTIATTNGNATPASDDLLCLNNNLSGNPFADSLFGSSQPQAAKPQQQEQNSFASFTNGRFGSSSDAFASDASFAAAFGDNQSTANQDLPAETAAITPAGLETNTAKLSLPVEPFGGRSASPSPTTELMRGAGTTPILANAPEGGFGEAVETAEEAPAPVVSAAEEKQSDFVWGGTTTPSTTSAVTNTATTDDLFGAPFEPVPATTTVPTAVVTPLSVPPQTEAVDRDLFGFDNEICDLSDQPLSAQPCAPPPSPFGGLDIGLSPMGGSASPDLRTQAIANAVGVALPMPAQHQQKIPAAVSGLEDLNFAIHHAMQPKLSPVLAASPTLSSSFPGPRPAFVGQPFQSGIMSGLPIGSATPPPGSTSLAQLPGGVAGTPTGRASSTPGYGTPPSGMSSPAKSVSGFGAPMAGGFDAFGDTLQPHATAPKTASTEKLSGSSILKGDLDSTLVNLVSNLDINGPKQALKKSSGHQWGSPKPSAKTTGPAGWTAPASVVPVAGGAVPQNVGWSASPQHGFPQMSQNAPAPGQWGNAFAQQPAAPGIFQQQQQFMAGGVRPNMGGPPMGGMAMGGMPPAAPIQQPGDICQRSFWCPLRQMNSNNWISGLAKELRLIIESLPLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6S3</accession>
    <name>A0AAV4P6S3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calmodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CALM_3</name>
        <name evidence="5" type="ORF">CEXT_728161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004151">
        <property type="protein sequence ID" value="GIX92713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6S3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="121"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX92713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="22668" checksum="A14B63F3554373C7" modified="2024-11-27" version="1">MVDYGLTEEQVAEFKEAFLLFDKDADGMITAAELGVVMRSLGQRPSEHELRKMVHMVDKDESKYFDSIFQSVQLSVGEVNSRSHLKAMLCITQRLLQTGNLPTILGKRHHRVRRVPEHDVQAAGVGQRDGAARGIPGVRQERRRIHQSGGAATGDDQPGGEALGRGGGGHDQRGRPGRGRTGQLQGCVYSNSYIPQKHSEFLLESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P784</accession>
    <name>A0AAV4P784_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_362171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004059">
        <property type="protein sequence ID" value="GIX91784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P784"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12074" checksum="0D4879F5E8E9C6C7" modified="2024-11-27" version="1">MSLVTIENVFVSSEAGFSEVNPIGLSNLQVFVERVSLVSQLRRKSPTVSLFGVLRLAPAAISVSWPLWKRRSRPESALFLRQKPGGKENRRGIGCAGRRAYLRLPPLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7J7</accession>
    <name>A0AAV4P7J7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_63801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021603">
        <property type="protein sequence ID" value="GIX91661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7J7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8199" checksum="067615E7B72E8D90" modified="2024-11-27" version="1">MRDSENYTIQNEYQATIVWSTSKDEARGKGVLNICLLEGGSNSREDQVFQKIHGSLHIKRLAGPGYPFRSTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7Q3</accession>
    <name>A0AAV4P7Q3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_350041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004086">
        <property type="protein sequence ID" value="GIX92015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7Q3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="510"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="637" mass="74044" checksum="A878F0BB842D0096" modified="2024-11-27" version="1">MSSRATNRVKFGCHNEIWNHAQNVFMNPGRSEFVKISKSEAFSKATDALETSNDRSEMADLFVSHFEFFWKIYNFLDPIERFCIVHTSPEFELGCQHVIQCYISLNLYYEEDDHRVTFHFDTFGNHELVDFVIKLQMRPVDGEGISGSAWNRYDFAFPTRVEAEREKLFLQGRAAFAEFLQDNELILHCRIATHTDPEHLSRNNFSSFLQTLSRDMQLLRSEKSLRESVVVVQNQQFSVHRSVLLARWPKFCDYLDYLSAAEERRELLPAVIPSERLIAAAAQISQLPAEARDQKVLEMTGLFTPDVADCLLHYVYSGQLRDMNPANKSKLIRVGRFFGFKKMIQKFHETALVSVGRSCRTSENYCVEWRRVDATHWLENPAVPKHQVIELHTEKCFCQISFAIDDSDKKYVIFIAKFLSDVPTNSGGGFSVLESPFSSYYDGAMEEGVLRIPLDYLQRDLTFQVELVYSHRSSLRLNVFVFLPAEVEPKPGLMSYSIDFYHLLKDGAMSDVHLMVGRGTIKAHRYILCARSARFRRDMAEELRKKCDTFRHYVNTAGYHPLKELLFFMYTGQLSKEYFHDTAVLNPCHDLWKAAFCYERRDLSDALYAFFKRVGFKKITHVILRDLFVILRDNYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9E5</accession>
    <name>A0AAV4P9E5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_254921</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021707">
        <property type="protein sequence ID" value="GIX92628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX92628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="21852" checksum="5F38F292CD97DDC8" modified="2024-11-27" version="1">MCLKSFLEYFIFATLIIVILYHTQVRTVKKVFIKNLFNCIVLASYGKLFMLPVLIWSKDEEYCEILIIFFIFLSQLQIMRVTTNLSSLVIVVLLIGISELGLLFVVNTVTDDVSAAATNELAERAKQAVQRLSCGIAKRDKDSAARLKTDLLLENRLTLWKIYIFSRSLVITSFGTLLTYGILLGTLGKENVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPX0</accession>
    <name>A0AAV4PPX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004826">
        <property type="protein sequence ID" value="GIX97841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14321" checksum="D64E105EAF25CAEB" modified="2024-11-27" version="1">MPKPNKDASCMGSCRPIALICMTCKLMERIILRRITFHLMNHNMLPQEQYGLARDILQSTKYSTLSNGLEMHTIYEAFQRHTLWPYFSTSLRLLTKFGKISYWVNALLSLMSRVARSHGIRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQ31</accession>
    <name>A0AAV4PQ31_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adult-specific rigid cuticular protein 15.7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_500351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004764">
        <property type="protein sequence ID" value="GIX97317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQ31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043315823" description="Adult-specific rigid cuticular protein 15.7" evidence="4">
        <location>
            <begin position="18"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX97317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="20780" checksum="280CA6F95B3A23B2" modified="2024-11-27" version="1">MIAKVAILFAALAAVHANVLLGGHGHLVNTGVSTSARTQDAFGNNAFGYTIKDGLGATNSRSEVGDGYGNRKGSYTITDIDGRARRVDYVADGHGFRASVKTNEPGTAASAPAAALINSPYAGPVAPVVNHVAPAASYAAPLAVAAPVAMVVSWSWWRPWFGIWIGSWQRSHPLNKVSPIFLISKWNNCCRPQFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQD4</accession>
    <name>A0AAV4PQD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_33661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005007">
        <property type="protein sequence ID" value="GIX99130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11586" checksum="00EEECF7DE86F40F" modified="2024-11-27" version="1">MACRGMQLTSSPPKHHSLIQKLKEVELFLRMKKPRLVPILSNAPSAITSSIQFDLVLGSICQRPPTEDNALPKGVPLIPCRQHRKPEAQKAHPERRTFGGKGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQQ1</accession>
    <name>A0AAV4PQQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_91091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004869">
        <property type="protein sequence ID" value="GIX98141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="15090" checksum="DF0C26004F17EE01" modified="2024-11-27" version="1">MCEHDKLHIRNSTVDWISAYYVTLDIHHHYLSVNLCGKIPWIGPTLQSWFVVDRPYEVFFPRGLEHIEASDDYHTGHMFLHCALKTVHQCSSELSFYIKQGYFSKSCSKSHQLFCKILIRSRYPYQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQT8</accession>
    <name>A0AAV4PQT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_272121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005051">
        <property type="protein sequence ID" value="GIX99474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10985" checksum="C83236986B49A3A1" modified="2024-11-27" version="1">MELNLNASLPLATFAPFELPVAPRNKERKSTFTGGQVHASRNMLRLLENDDHWELVLREAALTATAEQVKDLFAIILTTCSPSNSNRLEKLKEKHER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2R9</accession>
    <name>A0AAV4Q2R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_802481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005507">
        <property type="protein sequence ID" value="GIY02826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14496" checksum="137CFD03A8F2A328" modified="2024-11-27" version="1" fragment="single">SRTCPENDSHPGIIIMVSSQSGRKACVYAYPFINYIARKCHVYSNGGHLKWLRMEFGGLGPVFPGLVQKTTVAPTAGIIMRSSPKWQKACVYAYPFRNYIPRKCHVCNWGHLKWLRMEFGGLDLVCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3N6</accession>
    <name>A0AAV4Q3N6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_708311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005641">
        <property type="protein sequence ID" value="GIY03934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8434" checksum="7810594EBD15C222" modified="2024-11-27" version="1">MVEFDGYRRRAKVIVSVHAYRSLCPLNHRSCLGGRSDGDAAVSTNDGPHIQPQDVCGGPEHTWRNEVGFEARAASAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCU6</accession>
    <name>A0AAV4QCU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Orct</name>
        <name evidence="7" type="ORF">CEXT_136051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006053">
        <property type="protein sequence ID" value="GIY07147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY07147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="290" mass="32367" checksum="8E83C8753F46239A" modified="2024-11-27" version="1" fragment="single">FLPESPRWLIAQEKYSEAAVVLTRIAETNSKNIDPVELRLKIKKLGERIKKEDKMDEVKNTATDLVRYPNLRKKFLIVTFCWVADMFAYYGLQINVPNLGGNPFINFFILSAVEIPGLICSWYFMEKYGRRWTSVSFLILTGSSCLLVAIVPEGIPYVAIVCSLIGKFGASAAFMAVYQQSSELYPTTVRSIGMGMSGTFAGVANIVIPYVVFLAVIAKYIPFVIIGLVNLLAGISAILLPETLNAILPQTIQDAERFGRDQKCFSCNPRRTSIESLNEEQSPKLLNDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QI65</accession>
    <name>A0AAV4QI65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_212681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006149">
        <property type="protein sequence ID" value="GIY07745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QI65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7414" checksum="CC8ED529B80976EF" modified="2024-11-27" version="1" fragment="single">VEDNETMDHGVILVDSNLEVTSKTLQLPVTERLLSRQSSHQMRGVIYGRVAMISRDITIIGKSFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QLH8</accession>
    <name>A0AAV4QLH8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2_105</name>
        <name evidence="2" type="ORF">CEXT_337771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006326">
        <property type="protein sequence ID" value="GIY09042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QLH8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11655" checksum="ADCD8514A91D4162" modified="2024-11-27" version="1">MFILPLCTAVRYDGPHIKRFSFPSEVLAGDRTSAMCFVGKAAPPITFTWFKDGDEISNLPNVAIKTDEVFSVIIIRNVTESSGGNYTCSVRIHLENRAIAPIFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QR93</accession>
    <name>A0AAV4QR93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_87381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006634">
        <property type="protein sequence ID" value="GIY11324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QR93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8038" checksum="84D0C1E90A42F15D" modified="2024-11-27" version="1">MVGLGRDIPSTMVSLGRDKLGYFLNNGQMGGWELIYIEPPSGRYGATLGVVSCVSWWGALRMRPTLKTTGDVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT41</accession>
    <name>A0AAV4QT41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_308971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006792">
        <property type="protein sequence ID" value="GIY12427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10452" checksum="7FB0F4B894FD72BA" modified="2024-11-27" version="1">MVLHRSNKLPTHRDVSHRSRIRSAVELILFWLLGFPVGRGRWRRCRPKLEPSTSDELTGSRSLETKEGRTCELYGIPFFFFFRLARYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RC96</accession>
    <name>A0AAV4RC96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_681171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007703">
        <property type="protein sequence ID" value="GIY18967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RC96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9773" checksum="FD60AB3E4F361F96" modified="2024-11-27" version="1">MGVSNDDDKLQMQVIYEVRKLQMQVGMSAPPEEKECDRGIIWQIKGQGCTFPVIELETNIECSIECEVQRLEARSLIELVQTRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCT4</accession>
    <name>A0AAV4RCT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_420191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007792">
        <property type="protein sequence ID" value="GIY19783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10206" checksum="A4A26CDE0CFE4295" modified="2024-11-27" version="1" fragment="single">VHLLIKWVIVYIAIRIYNALQSKRRRFDLYDLRATGIRSSWFPNAAAGKRTGIALSGISLAGGEYPSKVTSCTFLLSWHVLNKDFDMKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHP4</accession>
    <name>A0AAV4RHP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Potassium channel subfamily K member 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Kcnk12</name>
        <name evidence="6" type="ORF">CEXT_114131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007763">
        <property type="protein sequence ID" value="GIY19518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF10">
        <property type="entry name" value="POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY19518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="22282" checksum="F9E8FD51EEA5E3D3" modified="2024-11-27" version="1">MTRGKGCCRVLHLHEDNTRFLLLGVVMLVYMAAGAWLFQWLEHQNEAEDRERYWKIYRRFLEKYNGTVDPADVRCCSGSMGNASASGIIHKRPRWDYPGAFYFVGTVVSTIDNVYEIRESLQLNTSRTTKFLHLFDMATIICLHDLMDVSEFRVTFAMARARKVGERQEDIPKKPRNFRAETFPGEFRKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLA4</accession>
    <name>A0AAV4RLA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_180161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008185">
        <property type="protein sequence ID" value="GIY22708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043551284" evidence="1">
        <location>
            <begin position="23"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9106" checksum="49E939933C56C4EE" modified="2024-11-27" version="1">MVNACTLFVLACILRQQILKNADRLPGMQKALINLARKRCPFYLETKAVVLGNQVSLRNKTFPVKDCWIAFSTRLFGNAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMG1</accession>
    <name>A0AAV4RMG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_250261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008023">
        <property type="protein sequence ID" value="GIY21470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9147" checksum="135F40AD77202C97" modified="2024-11-27" version="1">MNDEIFETAIQLDSLVVKLGIPLFKLSVSRDEVRRIDKVNKKSLPLVLSVETDLSPQINLKINSKRKSYEKLKQPGHTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPX0</accession>
    <name>A0AAV4RPX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_473631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008188">
        <property type="protein sequence ID" value="GIY22734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="20843" checksum="AB86D1B55D47CD66" modified="2024-11-27" version="1">MPRPGFESEDYSTKGLSARQLAIRRPEEEDNLGCGYLKKKKRSRKQNIEEKEKKEKKSKQEKRTPRGWAARKTDRPDWPAAVKAFGNQLCSLSPNQFYSGGSIPTTPKKAPKGIPSPEGRPPPYTLHHDFNTEILSGHPFDDLCTSSIPPSAQWEGILSYSFKVAIPDLAKDLKVIKGIRGKSLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRA4</accession>
    <name>A0AAV4RRA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_537321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008245">
        <property type="protein sequence ID" value="GIY23199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326:SF1">
        <property type="entry name" value="HTH PSQ-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326">
        <property type="entry name" value="TRANSPOSABLE ELEMENT TC3 TRANSPOSASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10966" checksum="1B535E9BA6509FD3" modified="2024-11-27" version="1">MMKKFEATGSLASRQRSGRPSTAAAVATTVEQTVQSMSAVAAHGKCSAREVSRQTGVSYGSVWKALRITLKRYPYKLQHKQELKPPDFDSPRFCEFGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUA2</accession>
    <name>A0AAV4RUA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_414791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008375">
        <property type="protein sequence ID" value="GIY24264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15997" checksum="71AB85EA46D708B7" modified="2024-11-27" version="1">MIPSSLENSAKHKNGGDKWFPERTGVIYGYLLYVWSVCVEKMQSRFRWNFPCNYFVSSSDMMSRDFWHDKSICWNALLLATGKREYEPSTGGRMERRKDGRVEGQTEGRKYRRKVGRTKDRKEGEGRPSEGRKDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWJ1</accession>
    <name>A0AAV4RWJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">XPNPEP3</name>
        <name evidence="5" type="ORF">CEXT_742541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008501">
        <property type="protein sequence ID" value="GIY25206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF4">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="4">
        <location>
            <begin position="68"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY25206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="239" mass="27668" checksum="36CE757F57F7796D" modified="2024-11-27" version="1">MLNISYLYCYLSGKVLRSLKFRKSIDILSSQWVFRNNIYTSSRSIRYTQPTAITHPHLLKNGEIAPGITADIYKNRRQRMIEIIRKTFPSSSENKTAHLIIIPSSSVIYMTEDIPYFFRQNSNFLYMCGFREPKSVLVLFTLPDRSDLDYESVLFIPRPTTHSIEWEGSKMDLNTVVNFLGVDKALYTDDLETFLQSFGKSFSKFTVWYDYSNTSSHPVHNKISDFILAYSGNISVESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S011</accession>
    <name>A0AAV4S011_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_595221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008661">
        <property type="protein sequence ID" value="GIY26274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S011"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9152" checksum="0F0FF25A9E2321DD" modified="2024-11-27" version="1" fragment="single">STSNSSEYDDQHMSARENIPQPRAEDRLSLSGNFRRLFTPNWTDSVPRAKRFVAPPPVQTMFLSPGERSYSVAAKRLGRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S543</accession>
    <name>A0AAV4S543_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Nodal modulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NOMO2</name>
        <name evidence="15" type="ORF">CEXT_720261</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008863">
        <property type="protein sequence ID" value="GIY27842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S543"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055075">
        <property type="entry name" value="NOMO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055074">
        <property type="entry name" value="NOMO1-3_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055073">
        <property type="entry name" value="NOMO1-like_9th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056191">
        <property type="entry name" value="NOMO_12th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056190">
        <property type="entry name" value="NOMO_5th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056319">
        <property type="entry name" value="NOMO_7th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051417">
        <property type="entry name" value="SDr/BOS_complex"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23303:SF14">
        <property type="entry name" value="BOS COMPLEX SUBUNIT NOMO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23303">
        <property type="entry name" value="CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23141">
        <property type="entry name" value="Ig_NOMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22898">
        <property type="entry name" value="NOMO1-like_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22904">
        <property type="entry name" value="NOMO1-like_2nd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22902">
        <property type="entry name" value="NOMO1-like_9th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23192">
        <property type="entry name" value="NOMO_12th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23194">
        <property type="entry name" value="NOMO_5th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49478">
        <property type="entry name" value="Cna protein B-type domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043596037" evidence="8">
        <location>
            <begin position="25"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="domain" description="NOMO-like N-terminal beta-sandwich" evidence="9">
        <location>
            <begin position="31"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="NOMO second beta-sandwich" evidence="11">
        <location>
            <begin position="117"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="NOMO fifth transthyretin-like" evidence="14">
        <location>
            <begin position="398"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="NOMO second beta-sandwich" evidence="11">
        <location>
            <begin position="501"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="NOMO seventh transthyretin-like" evidence="12">
        <location>
            <begin position="576"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="NOMO-like ninth beta-sandwich" evidence="10">
        <location>
            <begin position="738"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="NOMO C-terminal transthyretin-like" evidence="13">
        <location>
            <begin position="998"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1145"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1145"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1156"/>
            <end position="1166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY27842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1166" mass="130268" checksum="CAD04B04EDA7A9BF" modified="2024-11-27" version="1">MVMHINLLLLLKIIILCLIKNIFCDEIFGCGGFVKSSFNINYSRVEIKLYTKHGSLKYHTDCAPHNGYYLIPLYDKGDYVLKIEPPTGWSFEPSSVILHVDGTSDPCSLNQDINFNFKGFTVMGQILSRDGTTGPAGIKLLLKDSKGELVNETVSTQGGHYTFSKLFPGKYIIEASHKSWNFEKSSEEIFINSDNLKTNNDIIVAGYDVSGFVFSDGQPIQGVNFLVFSKKKLTAIPLGCDPEKVKGFSQTIELPYLCHVTSTPDGKFLFPSLPSGDYKLIPFYKGEHIEFDVSPPELDFTVSENSVLISENFQVQGFSVSGWIGTGPKGKSLSGVSVFINNEVHGTTDANGIYHLENMRSGVYHLDIKKPSFVFESVDMKINPNTPRLPNIYVSKFSVCGYLTVDEYPSGLGKTERNVMLRSIKDNQKLNIAVESDGIFCFNVPPGKFELEPVVSEAEVDFGLKFIPEKYAVDVVDESISNIEFKQFRAQVAGNVKCIENCTGVMLNLASLSQDRSHLETKVKDNGSFEFEKGLPGNYILSIIKEEWCFQSKSIKLAITDKDITNLQFHQTGFQISIILTHASTFKVKYPSGEFHDVDLHISKNVLCLPEMGIYDFIPVGCHLYKKDVFKFDTSNPAEITLSPTKHLVTGNIFTELNVTDIKVTVKKPNEKENIIALQEPLDKKGDYFRYTFSVFAQPNSDLDLKVSSKQLLFRPSTSIIKVGDDCMENAFEITGKKGVFLNGSVTPALEGVNIKVLVKKTNELYTETVTDKEGLFLVGPLEDESDYTVTAEAEGYVFTPLDNLGNFKAFKLAEIVVDVKSEDGTSLSGVLLSLSGESHYRKNNKTQADGRLAFSGLGPGQYFLRSMLKEYSFEPRTKMIDIKEGAQEYIQIIGKRIAYSLYGMVTSLTGEAEIGIAVEAIGVPNGQCSQYQEEAVSEQEGNFRIRGLHPKCEYILRLKPGADVNQHIERSTPKEHLFKVNDGDISGIRMIVFRYYGQLDISGNVVTNQEYLSTLKVRLYREEAPDQILHSVTLGQSSFFYLPSLPIDNKNYILRLESSLSNNAYYVQQPSLTFCANTSFYHYTFKFTPKVKSVEQEVTQGSVLALPVAIITLILAYNYTKFIPLFTNIAFVISSVINPARTQMSGDMSSDSVNIRKKLRPKKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TET1</accession>
    <name>A0AAV4TET1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_755731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011242">
        <property type="protein sequence ID" value="GIY45158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TET1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8837" checksum="25111DB30D8FA738" modified="2024-11-27" version="1">MGGVVKCDYLLMSYEGTTCKIQHLFALRPSIARPDSAIRELCQKAMQLKSQSDQCESMVIKPTKVHIMKSKKCTIKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TN69</accession>
    <name>A0AAV4TN69_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Outer dynein arm-docking complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tetratricopeptide repeat protein 25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ttc25_1</name>
        <name evidence="11" type="ORF">CEXT_495731</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011439">
        <property type="protein sequence ID" value="GIY46561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TN69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040111">
        <property type="entry name" value="ODAD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="454"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="461"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY46561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="483" mass="56216" checksum="55A677C61614FEF6" modified="2024-11-27" version="1">MIGTNEQDMDLDTFLESLMNPEYKPKFPFSFFFSEGCKYFRISMYKKAIERLDEALQTQPTNVQVMLTRAKIHIRLQQYEKAIEDATEAMQLWPSYSEIYDLKGQAEYLKGDFEGAYLTYLAGRQIRPDIKELRLGHQLCGETLGNSMVGMYGPAKLETDDKWKSKLCDVGIRFAKKSRNRIPTYERFSKDKSVLKELLSDEKVSKIHDVCKESLNFIETSERFWAMEKPLYTRRKASYPENQIAKKGTIAQYVAATKTRCLRYLQSGFTNLCIAEGQKLVELLESKPDMSRELLIKLKADVYHLLSFAYEIKPNVALCLQSLIKELEVSLESEYMYPQIRAYHHLGMHYLKKKEFENACSCFTGVIEALNPERLRKFLQNRKKYSTEMDESNVIDEEIREIEAAEIWARDFKENIDNLIPQPRSNKFFLEVIPEGIGLKNFLNENLNQSESNESEVYFSTEENGQSNESFFSTVSEKSKESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSL6</accession>
    <name>A0AAV4TSL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_56821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011756">
        <property type="protein sequence ID" value="GIY48824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="16365" checksum="73120ED4FCB84EC0" modified="2024-11-27" version="1">MNKVGSNPFEVVRDVLKRPKPLIAHRFTSRTHPIRRQKRRLNWNSFHERKEKVNVFGFAFLRMKATVFHFGPLQWPFCEHKEMESSFTIKALAPFTEYHIVPVMNTLGFYRVLSRSFFFFFFFLRTEWDTNSLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U0U8</accession>
    <name>A0AAV4U0U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_751061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012099">
        <property type="protein sequence ID" value="GIY51386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U0U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17828" checksum="4E856976AA7F4778" modified="2024-11-27" version="1">MQKSPIYRAIVFSRPLRASSYWKHLRVAGQEMKFAEEFVVSESDHRLDCRYCSFSKAKENSCNSSCGLWKTLGIKRKSKRKDPTTMKKWLLKKLREEKELGSAENIKADHIKWIYVKVRKQKTPIYRAIVSSRPLQASSYSEAPKSLRPGDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2H4</accession>
    <name>A0AAV4U2H4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ADP-ribosylation factor-like protein 8B-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">arl8ba</name>
        <name evidence="12" type="ORF">CEXT_443491</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012170">
        <property type="protein sequence ID" value="GIY51867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2H4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904115">
        <property type="term" value="C:axon cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008089">
        <property type="term" value="P:anterograde axonal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000247">
        <property type="entry name" value="ADP-ribosylation factor-like GTPase 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY51867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21291" checksum="1F4A0196A1DA79F8" modified="2024-11-27" version="1">MLALINRFLDWIKSLFWKEEMELTLVGLQYSGKTTFLNVISSGQFCEDMIPTVGFNLKKVTRGNVTIKVWDLGGQPRFRSMWERYCRGVNAIVYMVDAADHDKIEASRNELHSLLDKPQLVGIPVLVLGNKRDLPNALDEKEIIEQMNLSAIQDREICCYSISCKEKDNIDITLQWLISHSKSSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5X2</accession>
    <name>A0AAV4U5X2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_29711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012326">
        <property type="protein sequence ID" value="GIY53137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5X2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="15793" checksum="BD421B9E4E2FFEDD" modified="2024-11-27" version="1">MSQVVRDYFGGKKVLLSDVLLFSTRWKIRSVILNSSGGVAGIITGEKVNVENNSLRENIPCFNFGDLMIIVGLLFAGRKSARVTFLSKCLGGYHNPSTLSGNVLTQRAVLAKARAHVLIYAISANHEAVCCNLNSEQVFSSTGNIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8D9</accession>
    <name>A0AAV4U8D9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_312751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012461">
        <property type="protein sequence ID" value="GIY54041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8D9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10327" checksum="E96B5C0889683D5F" modified="2024-11-27" version="1">MIPSTQSSPSERDVSPKDMGKRFTGQRESSFTSGVAVSLCPPTPPLLVKGVGAEMNPWNLKVPGISMKNVFGKEISSRFYIGCPLISAGELFIIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHU5</accession>
    <name>A0AAV4UHU5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012905">
        <property type="protein sequence ID" value="GIY57415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="36198" checksum="348E3571E8F7323E" modified="2024-11-27" version="1">MGWAQKDCYINAYISSEDRNMRNLERNVLPQIFFIPSSEEKKKRKRRGENKERVFQKHLLKALTKQIEEELFYPNSPENSSSYSSGNNTPLINSPEKKSHFRPCYFIFFFSCSCSSSYSDHFPNSRSSCRSQLRTLEAPQCPGVLNNGQRHELTALKSFSSLLLIQLRPESSDLLKWTLSLSKLALAKNMSSCVSLRYGYGGSQKPIMVWAQKILIAIRKRRKAPHCPSVLNNGQRYNDGHKISFLASTNPIVPREHRSFKVDSLSLNSPWQKRCHLVCHYAAAAAAATRIIFPNSRSSCRSQLRTEEGTALSQRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UU73</accession>
    <name>A0AAV4UU73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_800061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013442">
        <property type="protein sequence ID" value="GIY61250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UU73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11436" checksum="EA5B96500D64E2ED" modified="2024-11-27" version="1">MITFTLDPWAEWSPMSINPSPRVHQSRRLCVGVPRGWARPSRPPFLFRKGNLLRRGDVGDTKELRTQLPANDFEMNYSIRVGRPNENLVGRRFRCRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0V9</accession>
    <name>A0AAV4V0V9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA-binding protein Nova-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOVA1</name>
        <name evidence="10" type="ORF">CEXT_516801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013767">
        <property type="protein sequence ID" value="GIY63638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0V9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22435">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22436">
        <property type="entry name" value="KH-I_NOVA_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09031">
        <property type="entry name" value="KH-I_NOVA_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000022">
        <property type="entry name" value="RNA-binding protein Nova-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047275">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047276">
        <property type="entry name" value="KH-I_NOVA_rpt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047274">
        <property type="entry name" value="KH-I_NOVA_rpt3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="9">
        <location>
            <begin position="66"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="9">
        <location>
            <begin position="160"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="9">
        <location>
            <begin position="524"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY63638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="612" mass="65135" checksum="FF58D76CB7E3E2AE" modified="2024-11-27" version="1">MSDIDKWADITKDCSYLPDNDLKVLKMVSLDGDNSESEFDDSRKRPLDSELDKEATKRSHQGGANGTYHFKILIPSVAAGAIIGKGGETIAQLQKEAGARVKMSKATDFYPGTTERVCLITGSIEGILHIHDFIMEKIKERPDPNAKMAIDFDHKQPAEREKQVKILVPNSTAGMIMGKGGSYIKQIKEESNAYVQISQKSKDYALAERCITVIGEMDCNRKACHMILIKIMEDPQSGSCLNVSYADVTGPVPNFNPTGSPFANPESVPNGAVKNSNTSYSSNSSLNSLSPTVNNSFQSPRTDTNTMAGITPFTEMGMNVPSIHPNDAAQAIESIKIMLRGSGYSEQAVTDISSAMSTLASYGILGLDINGVNEPVVSGMRMPASAIASGSMPPSNMTNMGMYTSTSGIPGMEAVSNSVATSGSMAAGSSMFNPVGNYGNGMPALGLGQDFSTPPSSRSNNRFFVQDGTAVFEPFQRTSPTLASPSAAALPVNNNSFGLGTSLSSGTPTFRKSSSTDRPSSLEVTKKTEIGIAENIVGAILGPCGKSLIEIQRCSGANVQISKKGIYTPGTRNRIVTITGHPKAVDTAHYLIERQIATEEADRAHQNTVGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3B0</accession>
    <name>A0AAV4V3B0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013902">
        <property type="protein sequence ID" value="GIY64616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3B0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8190" checksum="0D5F913E76B35C92" modified="2024-11-27" version="1">MGSTRGGWRVDSTATMTAVKVVTWVLRGRCGSVIDGMAQERLSADNAPEKESKWEKKYVFFVKNRLLLDKQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9V8</accession>
    <name>A0AAV4V9V8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_654751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014143">
        <property type="protein sequence ID" value="GIY66689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9V8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8960" checksum="6E6399E824B6A4F4" modified="2024-11-27" version="1">MVKELINPGDFWRVNNWRGERRCYSALFIREKLDETIPDNEETEDDTDVKRFHCLSHPPESQLGWEPFSYVVAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEA0</accession>
    <name>A0AAV4VEA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_708471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014368">
        <property type="protein sequence ID" value="GIY68368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="24419" checksum="AD3523ED987B6556" modified="2024-11-27" version="1">MTPGNRMKELLLTAYSDENLINPSTDGSHSIIFSRQHEEEQNSANVSEILLQAIFIFAIATEKNLKGLANWLILSFGCCRPYGGDIGFATSAYNEVNQQIWSLDLNSEFGGGSSIISFAPVFDGKDPDFYRRLEADGRKRIEVDLVQLLFLLKKNNPGGSASTHFTEDQSEGKDSSQAQVSENGIGTNPAGLGRLIVLAKREKSMSRNPLKPNAKEKQPKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMP2</accession>
    <name>A0AAV4VMP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_476681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014718">
        <property type="protein sequence ID" value="GIY70758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="243" mass="23292" checksum="3428ADC4C611AAAA" modified="2024-11-27" version="1">MGYFGEIIPSFSFQLEYTSRGFISVSFDTIYHTMKTAFILFAVALVSVAQAKMAEKVSEDDDFVVYRIPVRDLDLQSEASGMHEGGLAFGNSYGRSSSKSSSSSKSQSQSTGSGKGKGYGEGSSSAGHGTGHGGSSSGHGYGGSSGGSGYGSGGSGGSGYGSGGSGGSGYGSGGSGYGSGGSGGSGYGSGGSGYGSGGSGYGSGGRGYGHGGSEGYGQGSSEGYGQGQGQGGSGYGQGQGGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUD6</accession>
    <name>A0AAV4VUD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_178578_1</name>
        <name evidence="2" type="ORF">CEXT_612211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015048">
        <property type="protein sequence ID" value="GIY73219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="18473" checksum="129DDB6D205C403C" modified="2024-11-27" version="1">MTQAKLTEDIMSFVFNKLRFIHDSINIRNPTISSLAPRSVDVIVTGIYSGCHFHADSCCHGNVHGGHSSPGGHVHAGQPSENHLETVAIFLVHPTVDGRVVASVAHGQPVTSEPQVNDIGQVIELGVLVSHHHQRVKGQPAESEHENADNHHLNHLKRERKVVQEREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVZ6</accession>
    <name>A0AAV4VVZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_699051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015179">
        <property type="protein sequence ID" value="GIY74188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9754" checksum="DCF151A94873C7C0" modified="2024-11-27" version="1">MYPLTTYCQSQDQRKNCVFERRERNPNDISRRRRHTEGRKEKNWFPYSAARRGLADRSAANPEYQPEGPAVVQGAGEKEDRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VYS3</accession>
    <name>A0AAV4VYS3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Uracil-DNA glycosylase</fullName>
            <shortName evidence="7">UDG</shortName>
            <ecNumber evidence="7 9">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Ung</name>
        <name evidence="12" type="ORF">CEXT_765451</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7 9">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="7 9"/>
    <dbReference type="EMBL" id="BPLR01015354">
        <property type="protein sequence ID" value="GIY75527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VYS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.470.10:FF:000007">
        <property type="entry name" value="Uracil-DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003589">
        <property type="entry name" value="PRK05254.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003591">
        <property type="entry name" value="PRK05254.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="11">
        <location>
            <begin position="93"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY75527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="30267" checksum="CCE818114CC4FF79" modified="2024-11-27" version="1">MSKSPSNQKQKHDDLENDENGEKSLKKDAVERGKIIALSKKSPALFPNIGLTWFRALEKEFQKDYFKKLGDFLLREQNSHTIYPPRQNIYSWTTTAEINDVKVVILGQDPYHGLNQAHGLAFSVRKGIPIPKSLVNIFKELRTDIPGFKIPSHGCLYGWATQGVLLLNTSLTVRAHCANSHQNKGWECFTDAVIEWINTNLSGVVFLLWGGDAKKKSALIDKKKHLILTAAHPSPLSAHRGFFGCGHFSKTNDYLQKCNKTSINWANLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZ57</accession>
    <name>A0AAV4VZ57_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">[Histone H3]-dimethyl-L-lysine(36) demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">CEXT_811981</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015272">
        <property type="protein sequence ID" value="GIY74899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZ57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21743">
        <property type="entry name" value="CTD_KDM2A_2B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22122">
        <property type="entry name" value="F-box_JHDM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15555">
        <property type="entry name" value="PHD_KDM2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041070">
        <property type="entry name" value="JHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050690">
        <property type="entry name" value="JHDM1_Histone_Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002857">
        <property type="entry name" value="Znf_CXXC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23123">
        <property type="entry name" value="PHD/F-BOX CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17811">
        <property type="entry name" value="JHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16866">
        <property type="entry name" value="PHD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02008">
        <property type="entry name" value="zf-CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51058">
        <property type="entry name" value="ZF_CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjC" evidence="17">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="CXXC-type" evidence="16">
        <location>
            <begin position="326"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="15">
        <location>
            <begin position="379"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="292"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY74899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115847" checksum="B12EE5F75FAC5856" modified="2024-11-27" version="1">MFQVFWLIPPTEKNLALYENWVLSGKQGDVFFGDTVEKCARVHLESGDTFFIPTGWIHAVYTPEDTIVFGGNFLHNFGIEKQLRIAEVEDLTHVPVKFRYPFYNEILWYVVQRFVHCLLGKNYLICNESGEFLDPTNGSSSDVLNLTAAANKDPKLLSLTHNPLHMNGDKFSSPFKGIGENQHQETSNGAKSETTDMDSVAETKTVPTHIDLEVNGYKNASKEHIHITNWEYDGLKAILKWLLSLPPSKKGIPSYIRHPDALLEDLQILLNMHKDDDPRLAITGKPSLFWLDVKKPKPKPRSTPSSSSSSKGSKSGGSKSNNSSNARRRRTRCKKCEACLRADCGECHFCKDMKKFGGPGRMKQSCISRQCMAPVLPHTACCMICGRDGWDKLLNPPENENSSLMECSQCWEILHPKCLQEKNPDLPMESCINDDLPNSWECPKCCRNGKPDQIKPRQMKGKNSKGSDASRLSVPVSENGAVDYSSMNEVGAIQMMPQKKKVRFDAPNIKQEVLDESNCDDLEENKSINLSINQMNSLQSCNGNYTLPEKQEEISNGCPTSPTKEACERIKKAHVSPSHIRSCARYPLQLKKTFKNEQGKVLRVKNVNEKLDMRSKSKLNLGIPIKRHGETARERLFRNLKGLKKNLLIKSKSFGKCEEGTNGKPVVKDVKAVQSFDSIKIKQEVPCYLTEEAKPELTNVSAEKLVKSEKLSNKIPNAENPKISSILRDNPHLKKPKYVVRPAPIVEDNNEEKIRNSNTGIENLAVEKEVMLPVFQFLSVKDLYACQLVCKTWNRWSVDPRLWTVMDLTRKKISANTLVGIIRRQPVTLNLSWTNLSRKQLAWLIARLPQMKELILSGCSSASVVALCTCNCPLLRSLDLSWVEGLNDSVIRDLLSPPPDSRPGFIENKTRLRHLTEVKLAGADISDVSVRLLAHHLPLLSKLDLSHCHKVTDMGIAVLGAAKATRLQFLDVSSCSNITDTSLEALKRCNNLAHLDLRDCGQVTEAACSKFVGQNRQTLMQKEAKFIKKHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZU5</accession>
    <name>A0AAV4VZU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_572231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015416">
        <property type="protein sequence ID" value="GIY75917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19711" checksum="D8EB3E7CFC822DFF" modified="2024-11-27" version="1">MQPGCKEADDVANEINRSFEIIKLLHSKTHISNKDLPHTKEEYDRILREAGRETDEYQRTHSTTDRDQIIQKAIYVLGLLPKKATQQHLKEIEEEQNSKRPRTSDAEGFIPVPRHLTAEPNTVLEAEKPMETENQFAVLETVTDPEIIPAQTQMKLDSLLSSSYPTKNGQNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5T6</accession>
    <name>A0AAV4W5T6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_291301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015593">
        <property type="protein sequence ID" value="GIY77239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5T6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13495" checksum="54CB8027CC8C626B" modified="2024-11-27" version="1">MTNRGCGDSSITVCCCASTGKVLLRALRKYLYPRFLFPVDNPSSDLDYDPDDGPTITKEALHCQKLLEAEKDLAHAKVKYDAALGFINWQTSSAIMNLDKMSTSKMTMEAFHLGRGSIQEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7G0</accession>
    <name>A0AAV4W7G0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="3 11">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_61731</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 11"/>
    <dbReference type="EMBL" id="BPLR01015772">
        <property type="protein sequence ID" value="GIY78602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7G0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11850:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01121">
        <property type="entry name" value="Diphthamide_biosynthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY78602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="415" mass="46651" checksum="6D68D1B30F0FB5D6" modified="2024-11-27" version="1">MSENNETASKAVIISAKPDRKIFRPKRKAISGIPAEISENTEILQAISVLPSNYNFEIPKTIWRIKKCGSKCVALQFPEGLLIFALPIADILETFTNVETIILGDVTYGACCIDDYTSRALGADLMVHYGHSCLIPIDRTENLNMLYIFVDIKIDSLHLVNTIEKNFEKGPLALLSTIQFVSTIQQIASDLQNLGYKIEIPQAKPLSPGETLGCTSPKIRNSQKVVFIGDGRFHLESAMIANPTLEFFKYNPYDKKITQEYYDYEKMTQIRRKEVQLASTSQNFGIILGTLGRQGSPKVMDNIRNILKCNNKSHVTILLSEIFPDKLKMFTGIEAWVQIACPRLSIDWGYAFDKPLLSPYELAAAMKEIGWQKQYPMDFYSAQSLGSWTPNHTPSIEDKGSCKSCTDCECTNNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8P5</accession>
    <name>A0AAV4W8P5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_21121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015838">
        <property type="protein sequence ID" value="GIY79037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8P5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12071" checksum="9408F14BF125FAF4" modified="2024-11-27" version="1">MCFRIRQVSKISGMSKCPIFNSNNLSLTMPNSVIRMNSPICLKLSRKGSVVDLVAKESMRLVFPVISAPSTNIYIMHKLDKSKPLKSKSNLLYTNLGRSSENPSPSAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBQ1</accession>
    <name>A0AAV4WBQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_733931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015915">
        <property type="protein sequence ID" value="GIY79648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13963" checksum="284DCFE8E9063D65" modified="2024-11-27" version="1">MPFPSFKLARERKHLFGLISTNSELRAAVSVDKLVLCKSNSRMGSCCALIDSRSVTKGFGHQQATTCPSSHNRLPFMKTCLRRVTTSARAETSVRADVNNSELRAAVCRQGCFANRIREWENVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFM0</accession>
    <name>A0AAV4WFM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_571551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016071">
        <property type="protein sequence ID" value="GIY81043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="339" mass="39458" checksum="82B18EF5991C58E3" modified="2024-11-27" version="1">MTLNIYRDRNKNQLLISIEAIHIFTYREHLRIHLQQRDHLHIHLLQPSTYSPTCAIHLFTYYSHLHIHLPVPSTYSPTTAIYIFTYQCHPLIHLLQSSTYSPTSAIHLFTYYSHLHIHLPVPSTYSPTTVIYILTYQCHPLIHLLQPSTYSPTTAIYIFTYLCHPLIHLLQSSTYSPTSAIHLFTYYSHLHIHLPVPSTYSPTTVIYIFTYQCHPLIHLLQPSTYSPTCAIHLFTYYSHLHIHLPVPSTYSPTTVIYIFTYQCHPLIHLLQPSIYSPTCAIHLFTYYSHLHINLQCHPLIHLLAPSTYFAYWCHPCIHIQGPTTYSPTTTKPHPITVCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGS1</accession>
    <name>A0AAV4WGS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_766661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016087">
        <property type="protein sequence ID" value="GIY81151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11000" checksum="1DEB97CDFEDE871E" modified="2024-11-27" version="1">MIASIPSTYFNRMVMIPQNRFANFTFPYIDDPLKDFPNSPFYRFPSSHIPLFIVFQKGCSSIPTCIIKRFLFTTLSSPPPPFNQLKRLQQYLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJ66</accession>
    <name>A0AAV4WJ66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_44471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016290">
        <property type="protein sequence ID" value="GIY82822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJ66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11439" checksum="9554EF5DA08636D1" modified="2024-11-27" version="1">MYANEGITLPSWRETLNVLRLEKTKVGHAGGSRGVVAAPGGRTGRAKAPGAEVPASLARPDPELSAALSYGGTFPSFAKYRVFDPFKYDFFSPVVLNDRQGKWIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMW2</accession>
    <name>A0AAV4WMW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_277061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016283">
        <property type="protein sequence ID" value="GIY82770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9154" checksum="000B332B84010526" modified="2024-11-27" version="1">MKQWFKQAQMTVLTDDDLQSAYSTAAEDKDGIQFTELMSLIGNISAAKQMDKKDITDRLCGATKPQQTISDDMAAKDYKDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WY59</accession>
    <name>A0AAV4WY59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_689821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016984">
        <property type="protein sequence ID" value="GIY87847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WY59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13620" checksum="96E6258833AEA3E1" modified="2024-11-27" version="1">MTVDPEPRLPPIMVRFNDGLKEHVAAISNRIRVKLAGEQLKIFPVNSDVHRAVTRYLTEKKLEFFVITPKKSMLKGLPVSYSTAEIEEGLSELGLNFVEKSPENVNIFQKTYYFPLGLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0Y9</accession>
    <name>A0AAV4X0Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_715441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017106">
        <property type="protein sequence ID" value="GIY88822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11870" checksum="14811A3E20AF6918" modified="2024-11-27" version="1">MTAGALVTPICQQTPSIIEGEALGEVIHWRTLLEIRKVAKGLANGYLCDKGNCCDLCGEVSLMVLLNNSRGFIFFMCFCFVLLNIFSIYTDNRYVFGYLHFGLMDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X477</accession>
    <name>A0AAV4X477_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Solute carrier organic anion transporter family member 4A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Slco4a1_4</name>
        <name evidence="1" type="ORF">CEXT_607451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017214">
        <property type="protein sequence ID" value="GIY89488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X477"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF76">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11385" checksum="86CB9D1C55BB60BA" modified="2024-11-27" version="1">MVLGSISSFIMALPYFMYGTMRNSEAFEHSISRVSEVKAQFCDQDYNSIQGTCGESITTPVLTIFVMSNFLKGLSGCIFYTIGTSYMDDSIKKKNSPIYLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X577</accession>
    <name>A0AAV4X577_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Disintegrin and metalloproteinase domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sup-17_2</name>
        <name evidence="4" type="ORF">CEXT_664351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017311">
        <property type="protein sequence ID" value="GIY90327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X577"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051489">
        <property type="entry name" value="ADAM_Metalloproteinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001614">
        <property type="entry name" value="Myelin_PLP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45702">
        <property type="entry name" value="ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45702:SF2">
        <property type="entry name" value="KUZBANIAN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01275">
        <property type="entry name" value="Myelin_PLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="585"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="677"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="721"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="767"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="849"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="3">
        <location>
            <begin position="203"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY90327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="907" mass="101741" checksum="52962CAA38B8C045" modified="2024-11-27" version="1">MLIQFHLCSAKIPNGFSDYLKSFEIAECEIVRSENKRSLIKNNGTPHNDEVEVLLKSSNKTFRLLLFEDELFNEVLSQTRLYSKNSSSDFRNNANKYSNTKFYEGIVKDKPRQTSVIGYLHHGIFSGTILYENTEYFVEPLKFLIPSSPFSLKVAIYKIEDINLTNTNATEPFLDWSLAFRISNITVNVSREGISLDNITDDLSCDIEIVADHTLYQYFRKNTDKLSAYLYTHAKHADKIFRKSDFTMSGKPDGIRIKVAKISIYKTANDLNYPMVSANSVSEYLTEFIKRKQESQYCLSISLSYRPFVGSAIGESFIPDVSYRNLAGGICEPTIFDADQNSMNFNIATINVRHGQRPLLPLPISLLAFVHEIGHGFGSDHDNPNNKPCSPDSSKGKYLMHPKTLPLLEQRAEFSPCSRIAIREVLRKRGGCLKPVVATCGNAIREGAEECDCGWASICNLVDSCCNPSDIEFPAVGCTLKGSGSKCSPKESDCCTDDCATVCAIKDLEECECRDNLLEECLICCKTSTGCVPASELGILNPAGGKYMRKMGSRCNYGIYHCDATGICGEHRSVLSEPQHSKRNTSLIIFLSVLFYYCDYIFSRWLTLELLGTTKDDTTARLTFSTQIPSGVNRFHRLQQCAQGTMQTLQYPNSCLMMCHMLPKLSKCARCMTRVPYGTLIATIFCCAGVLTFLICLYRAVRLTLRMFDDVFKYNLEWLSSVQLAFIIVGSFMGLLAVTLLIVGICSTGATRSKVYRGWKSRVGGRISTALCMVIVYILNLAWLGIACCLVVVVFTFHVARQLCDNSTGCIDLQQFHFLFPNGTDLKLLNICSRKAFCTDAVVYAEPYYILSFVASIVVIISLLHYIMCLAANYTRIKDQENSKTCKSFNICKIPKWGHCQKTDSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8C0</accession>
    <name>A0AAV4X8C0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_364811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017405">
        <property type="protein sequence ID" value="GIY91360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8C0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15039" checksum="69C3CCAE79BF2323" modified="2024-11-27" version="1">MAALMSRSNVSPFRLAGVLLLVKYYGELVKLITLAETCEGDCGLCPSVALSVCEVDWLYLINNWKFHYDINDQHGDSRMVCAVHMLSPEIGMFPSPNAYSNKNHLTQLVASRRRQYYTKYLQVNPSYPGSVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBN3</accession>
    <name>A0AAV4XBN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_621591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017462">
        <property type="protein sequence ID" value="GIY91838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12406" checksum="8707702BB900CD26" modified="2024-11-27" version="1">MTDSMKSVQTARKSLNSQTLGQLPPGIQVITRTDSSKASFHSSVLSDTKKATKNENQLTKIKGSSSKNVTNFKQKTNVSSDTNKTHASSLLPQLIPKSSKKMYLEKKFESWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDT5</accession>
    <name>A0AAV4XDT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_675851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017506">
        <property type="protein sequence ID" value="GIY92159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13353" checksum="E9B0CC9EE869D645" modified="2024-11-27" version="1">MQCRVSLIDWIKLRRDMFSKMGNDRFCAVRDLCNVKIVVSFENATTRMHLVVGIESITQKIHFNKCKTMNLKDRYRPNPRHHDKIYSSATRTRGKRGAFVTARRFALSCARETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF38</accession>
    <name>A0AAV4XF38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_43401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000136">
        <property type="protein sequence ID" value="GIY92404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="19397" checksum="09CCA2AB9766F38E" modified="2024-11-27" version="1">MNKEEACSDARKLITKYRKLLTWWTFVREVPRLMNSNIDVIFDLSTYFAMPFNIFMNQVEPMKRSRKKCIALCSGIRNDLEELCKNVDRIMNTVVTYNSESGIYDEYKIEYKNAMNDAWIIFLKLRDCKEEFIQFCKLAYIIFDGFQLKFDEKECSTLHLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG77</accession>
    <name>A0AAV4XG77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_37602_1</name>
        <name evidence="2" type="ORF">CEXT_134351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000342">
        <property type="protein sequence ID" value="GIY94045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15390" checksum="9CBC8570DA6657AA" modified="2024-11-27" version="1">MAACSTDSSDSNMPVDDHQNQTKGNISKRDTETIVSFSPRPQRVQRLNRRGFYLSNIGTENLETSTQKTDIGKSRCGQQKKTSINNDQKLKSPEKKIIKLNFSENGLKRKSNESNSNKDNSQEIPPKKKHAIITWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHY6</accession>
    <name>A0AAV4XHY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_41791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000405">
        <property type="protein sequence ID" value="GIY94556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10665" checksum="65500AB0E510833C" modified="2024-11-27" version="1">MTIQATDSPSIRQTSLWTVYQKHSVCLPRCISTLTSPVAHSLLYYNYTLHNKLYSLAVCGSEYVKHATHNTNQIDTFHPLRLTTQRTLKAALSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XI69</accession>
    <name>A0AAV4XI69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_156449_1</name>
        <name evidence="3" type="ORF">CEXT_173711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017666">
        <property type="protein sequence ID" value="GIY93484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XI69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055470">
        <property type="entry name" value="DUF7042"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055471">
        <property type="entry name" value="DUF7043"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22255:SF9">
        <property type="entry name" value="LP06548P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23069">
        <property type="entry name" value="DUF7042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23070">
        <property type="entry name" value="DUF7043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7042" evidence="1">
        <location>
            <begin position="19"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7043" evidence="2">
        <location>
            <begin position="103"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY93484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="409" mass="45317" checksum="BF6395A99FE193E9" modified="2024-11-27" version="1">MFPFVKRPAYREGYSLQVRTEELVCLATWKEGSTRYLVGKLEHRVAKADEDKFRCFVYEQTEDGNGYLVAQSGDATCDGLFTPLEGSRTMRLSKVGLWSNHPHAKCHYPEWFTVYRHWRGLDGRLAYDISHKNGSFRVSNATTGDVVKRVVCAQDSPPHLYYPPVTADSTVATSVGSSKTYAQFVVHVTAGCNSGYACLRIHKRAPHVVELQTSNRLSPLASDACLGINFELNPSEIVTLTTQSYGSLECPIAGIYSLEGNSRHLSRLISLNTEEFWPCAGTTTLTSGCSAVDKMELLQDCTTERKAKSFQCRGSWEENGISYVIATAVGTRKHLCLAYTVNDRMIHFSGSMEECLRNVQIGREGLIAINGTSRGFCPATGASTLSNYSPYVTMLCVLMATVIRIFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIF1</accession>
    <name>A0AAV4XIF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017678">
        <property type="protein sequence ID" value="GIY93559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12854" checksum="5A45C0C35F413553" modified="2024-11-27" version="1">MKFGARLTLNCLPENHLIPYNKKMGTINLKVLLGTFYSHTIRKWARLTLNCLPENLLIPYNKKMGTINFEGLTGNLLLPYNKKMGTINFEGLTGNHLIPYNMKLGPINFELSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKR4</accession>
    <name>A0AAV4XKR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_69371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017798">
        <property type="protein sequence ID" value="GIY94531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9165" checksum="200D338E35AB487A" modified="2024-11-27" version="1">MKCKSEIKRIIDLKTKRNYCKNKRQRRRERTGKKDQQMKQGQRQWIGLFDEPSSIIQAPTYYTQFEGGNETTATKPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNP1</accession>
    <name>A0AAV4XNP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017967">
        <property type="protein sequence ID" value="GIY95825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="208" mass="24123" checksum="5672FDA31B0BF9CE" modified="2024-11-27" version="1">MKQHRKARKRDFYMFIEEGRVLLHIFINEESNKQIQHPKSLNRKELHKAEGVGKKVSYAPNLYPENTVMILQTNARTEIPVYMASISGDERRNFKSRSSPPFPPDTTPGILLFYLLPFKSQNVNAKEGEACPKNLSLIEEFNFYVDGVLKTAYLTNRKRANNSFDSMDMSEKWKIKSFTSWQKCGCKIDIRESVVEFDFLLKCHGDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSF9</accession>
    <name>A0AAV4XSF9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">par-1</name>
        <name evidence="10" type="ORF">CEXT_209001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01000811">
        <property type="protein sequence ID" value="GIY97637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12196">
        <property type="entry name" value="MARK1-3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.80:FF:000001">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KA1" evidence="9">
        <location>
            <begin position="57"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY97637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12314" checksum="42BF263C39E996AC" modified="2024-11-27" version="1">MNDDQVKPRSLRFTWSMKTTSSRDPNEIMQEIRKVLDKNNCDYEQREKFLLLCVHGDPNTDSLVQWEIEVCKLPRLSLNGVRFKRISGTSIGFKNIASKIANDLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWE4</accession>
    <name>A0AAV4XWE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_348641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000883">
        <property type="protein sequence ID" value="GIY98103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="202" mass="22992" checksum="9062F11162D1C718" modified="2024-11-27" version="1">MLHICRELFMTRIICSIEYQSIYHPCLAHDTAPQINCHFVAMVTLPSGAPQRCEPAIWRASSFIICASHTTRPLKSTVISLPWLHFLPEYLTDTKQRFGQLTRLFPFRTRHKKKPKGTGPYDGRKGSGNEAMRMSEMEKNKKHSSSVSSYYPQPYATTHLSGRGRNDDGTDSGYHQVTDHFSRLSLKLIAGFSLEDNSSEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXD8</accession>
    <name>A0AAV4XXD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_146911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000935">
        <property type="protein sequence ID" value="GIY98550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11781" checksum="BBC0A30C43C97B7C" modified="2024-11-27" version="1">MDVSFDALLSFLPFTNTKQKGTSFKERDGSVEGVAQKIVTLTMKEILAQSELLSYLAVTVILLGFGFCPNLRDMKRVLLRRHRDFSFLKDCLQQSRQQIEPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYF8</accession>
    <name>A0AAV4XYF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_228511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018356">
        <property type="protein sequence ID" value="GIY98914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9634" checksum="CF0603BB7D67725E" modified="2024-11-27" version="1">MIPTSGINSIQPTQQLASFVSLSSDIPLEIRSFSMDTLCTNKEESTLNRTETENPKCFASHFSFTLYFAEFSRKYFLHFKSHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYM7</accession>
    <name>A0AAV4XYM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_211151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018420">
        <property type="protein sequence ID" value="GIY99413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12297" checksum="88DDDC78C6FA63D2" modified="2024-11-27" version="1">MRSFIRDYPVSEIKNRKRSKVRNRSRSKLPSFQKAGTKAGELRTLSSHPLRVPDAVCACATFVKVCRSAPSSTVKPTGSTGEQQHNANSVSQNSLPASSALCRIAQQPDAQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1A0</accession>
    <name>A0AAV4Y1A0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_435621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001214">
        <property type="protein sequence ID" value="GIZ00848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1A0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11659" checksum="4B6750117ABD0A40" modified="2024-11-27" version="1">MSFVDTFLISRTCSISPLDLARRVSYRVQQAPTYSVVGKVGPLNAAITRDVLGRLYKAKIRLSIKKIEVQGMPGFCKSRRKRVSSEREKELIFPLFPQRKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y292</accession>
    <name>A0AAV4Y292_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_649331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001143">
        <property type="protein sequence ID" value="GIZ00280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y292"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11848" checksum="EE223DC6F83C2490" modified="2024-11-27" version="1">MVCKHHPLKPNASPDLSPPRFGGWARSWEHWFDPQALALRYAGSDTRCGWARRSQIAARTDTGLPTWSAARRDHKLYSAEKRSAHFSEKKNNIIMFMAQKLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y438</accession>
    <name>A0AAV4Y438_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">STK3</name>
        <name evidence="16" type="ORF">CEXT_127421</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01001220">
        <property type="protein sequence ID" value="GIZ00907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y438"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21889">
        <property type="entry name" value="SARAH_Hpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06612">
        <property type="entry name" value="STKc_MST1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000075">
        <property type="entry name" value="Serine/threonine-protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.170.10:FF:000002">
        <property type="entry name" value="serine/threonine-protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.170.10">
        <property type="entry name" value="p53-like tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024205">
        <property type="entry name" value="Mst1_2_SARAH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036674">
        <property type="entry name" value="p53_tetramer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011524">
        <property type="entry name" value="SARAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11629">
        <property type="entry name" value="Mst1_SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50951">
        <property type="entry name" value="SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="23"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="SARAH" evidence="15">
        <location>
            <begin position="455"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="372"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIZ00907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="509" mass="58214" checksum="9ACADF743E0D9DC5" modified="2024-11-27" version="1">MKNVGKPEKERRKYRCPYAVRANQMRPISGSTSYGSVYKALHKESGQVLAIKQVPVDTDLQEIIKEISIMQQCDSLFVVKYYGSYFKGTDLWIVMEYCGGGSVSDIMRLRKKTLTEEEIATILNDILKGLEYLHYRRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIQEIGYDCVADIWSLGITALEIAEGKPPYGDIHPMRAIFMIPAKPPPSFREPDLWSTEFIDFVSRCLVKNPDERATATELLQHEFIKNAKPVTILQQMIAEAKEIQESESYRQDRLQNLDFDDDEVDSHTMVEFLADSGTLVPSNNDSGENNTLIAHSDSNTQLVCANSDIESDLGTLVINSDKEDEDSTMKRHDTAPGEKKENYRTPHPNHFIQTDNFSNKNYQTPKEKRFSNQLQRQLNQISNVGPSAALHEPSKFQRSFNEGDFDFLKFLSYDELSQRMASLDSEMEQEIEELRRRYQAKRQPILDAMDAKKKRQQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y460</accession>
    <name>A0AAV4Y460_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_709691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018723">
        <property type="protein sequence ID" value="GIZ01800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y460"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9081" checksum="1FF72C529EB4D434" modified="2024-11-27" version="1">MKNDLIDDSVITTPKLNCDNNKDFYHDIGDEKPTLISGNKEVLLDVTELENIMLMLRTIQGKGDISSSRLELYSEEMDFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7C0</accession>
    <name>A0AAV4Y7C0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_131121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001592">
        <property type="protein sequence ID" value="GIZ03346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7C0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17183" checksum="6E168B12D0C7AF06" modified="2024-11-27" version="1">MDLTRETNSTMNLTRDANSVMFLTRDTNFGVNLSRDRNSSLHLTCDTNSALDLTHEIYFTMYPTRDTNSAVNMTQDANSVMYLTRDTNTAVNLTRDANFAMDLTREINSMMDLTRETNSMMDLTRDTNYAVNQTRDANSVMNLTFAINSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8M6</accession>
    <name>A0AAV4Y8M6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_752011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018937">
        <property type="protein sequence ID" value="GIZ03368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8M6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11307" checksum="1AB89AD0F128C098" modified="2024-11-27" version="1">MNPNEPPPVQLTRRRDGRTLLTDREPAGTGSAESTPSWAQRAVPPNALHLPLRRTPCRRAGGPSRAVLLLTAKSPPTVRFAAFCLRLSGYEIVDEVSCFPREC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAY0</accession>
    <name>A0AAV4YAY0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_768411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019062">
        <property type="protein sequence ID" value="GIZ04293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7927" checksum="C4D07A25F609EDFC" modified="2024-11-27" version="1">MWSMGDIVWAKINDDWWPGVISNPENYKYVMVGENKIFVERFGDLQGLEGGHKIIFAAWRTLKPKTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCK0</accession>
    <name>A0AAV4YCK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_13371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001692">
        <property type="protein sequence ID" value="GIZ04100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7749" checksum="8D859F243E7DA5BD" modified="2024-11-27" version="1">MLSQCNTSHNIAVIKEEKSVSSGILPNRIGSISFDSLDDAINDFPLLSSVWIDLERKEILRIVFDLQIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCL0</accession>
    <name>A0AAV4YCL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_70761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019234">
        <property type="protein sequence ID" value="GIZ05191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="14018" checksum="4C0E4356D7F6B42D" modified="2024-11-27" version="1">MSFLQWNFRSLQNKNIWLHQPPFTTSEFWVFQETFLKADDRLSFPNKIFFRIHRNNRTGGGLLIGIPPNMSGHVIFENSNDPDLEMLAVEIQSHNVTFTIVNIYAPHGFDIHQVQNFSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6G1</accession>
    <name>A0AAV4M6G1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_310271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001891">
        <property type="protein sequence ID" value="GIX67641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20625" checksum="860D33B352DFA038" modified="2024-11-27" version="1">MRTAAGRRHARLTRCWRDSSARIVRADRHTGLGSTERRGTLVSLADNSVYCGHRQCSSGFICSGFCSLMPRLHRQMGCRPSILNDTLAGMTAWGGLFCLCNDYTRRRFIGSDLFDVIWNNMHSYGCWKLKGWSPKHCRSNAFTDRVTAGMGASMAWIKTACGIRLKPVPHRLSGYHQDQPQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7G1</accession>
    <name>A0AAV4M7G1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase II elongation factor ELL2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ELL2_0</name>
        <name evidence="3" type="ORF">CEXT_774431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019467">
        <property type="protein sequence ID" value="GIX68185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019464">
        <property type="entry name" value="ELL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10390">
        <property type="entry name" value="ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase II elongation factor ELL N-terminal" evidence="2">
        <location>
            <begin position="33"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX68185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="425" mass="47742" checksum="179A334347931211" modified="2024-11-27" version="1" fragment="single">MCKSSVDDDDDDDEQDPEPRRYLGCLVYLFMERRKVKVKRPGLVVSPVKYSPPTSSMMNKVAPIKPVANISPRAPTPPSIPVPKRPEPPKPKPIPPPPPQKNPELMRQPIRDRIIHILALRPYKRPELLMKLKHEGEEAEIIRKRKQQHLNSNNESPPSNSQSNTSPLQKRFTNESLPELPPSKKQRISHYKAEQPRPTYGNSSTESSSNSFPKKSFSPGPVPPSMPNGFGFHQEDSNSNQKSPTSDSYPNTPPPLKNVSNHSTSSLNQRTREDNTRNHSPGSNNSMGVPLRKPSFQKVYPMSRNQRHDVEERTPSEPHHPKSYVNSDMGRTQTLSHPQSVDSVSSSKVSPDSNTRYRVEESKTELCSKTSTNGYVNNNNSINKGNYNRNKSSYIDRSKVTSTTNGSCSNSPHSSCDSRDGMDYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MB89</accession>
    <name>A0AAV4MB89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_508881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002013">
        <property type="protein sequence ID" value="GIX68997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MB89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12421" checksum="D596AC03A587DE03" modified="2024-11-27" version="1">MGTSSLPFGSRGSRNSGAVRRAAKVNGGQLRGGLLFLHPHPLARVPYYLGTIPNDNRVTSPPTALISPTSGKKRSRQSRASLSPNKAPLSPPLADCFGLCFPAQSHLLSDGVLVCKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCB2</accession>
    <name>A0AAV4MCB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_462021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019586">
        <property type="protein sequence ID" value="GIX69465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11174" checksum="33E8EA86ABCAA2D1" modified="2024-11-27" version="1">MEATSYCSNIADSKQALPEVGLSPSHNKDYNNSKCNTDCDEINRIWRSKLQNENLKEKDESIYLDYLDSKSSSFPSSSDSSPKSSKKMNLQKYLVKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCI3</accession>
    <name>A0AAV4MCI3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Zinc finger protein ush</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ush</name>
        <name evidence="15" type="ORF">CEXT_303171</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002117">
        <property type="protein sequence ID" value="GIX70177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061629">
        <property type="term" value="F:RNA polymerase II-specific DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007507">
        <property type="term" value="P:heart development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039746">
        <property type="entry name" value="FOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049361">
        <property type="entry name" value="ZFPM1/2_PR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034731">
        <property type="entry name" value="Znf_CCHC_FOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12958">
        <property type="entry name" value="FRIEND OF GATA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12958:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN USH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21182">
        <property type="entry name" value="FOG1-like_PR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51810">
        <property type="entry name" value="ZF_CCHC_FOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC FOG-type" evidence="14">
        <location>
            <begin position="366"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC FOG-type" evidence="14">
        <location>
            <begin position="694"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="794"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="243"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="502"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="556"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="591"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="741"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="929"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="243"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="601"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="631"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="741"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="940"/>
            <end position="977"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX70177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="997" mass="111048" checksum="D2E45428C3279B23" modified="2024-11-27" version="1">MNVKRILKKNQTPLKENSHIERKKMFTFLHFLKKGCSGGRRDPWFTRGEPTDLDEIDPELNLPSSHLYLREFGGESLVLAKQRLTAGTVLGTYKGHLHDPHSEDTNSLLKVNRSDGGSPVHVMLEDEGHWLKLMRTANLPTEANICLRITGKDIVCTVTKDVNKEVELKVTCRIVDREEDSLEFDQIDSKSENSPLHSVKEICESDSIKSESSEHDKDLKDCMKSEKMLDFAPGAIVDIREDMSSKHSLKDSERDHDVKKHRTENHDDSGCDVRDTRDEVSSSNVHRPPSSDDKAYEISQARSSSETSPREKNKSTEVDIKPNFSQHGEEQMIFRCPHCSFASVEHYAFNKHLQSHRHYTIKKTSKMTNSKSYCEACKIQFKSIDTYHVHKQLYCKSRNEKEETSSSPTLPEATPGSSFKPGPETMIIRNGINGGVTPSIIQPQAIYAAISTNPLILLPCSLVNGQGLVPQRGVIPTGAPGIVLQTGIACPTIVEKPAVAKVKEESPPSRKTSHPIMNFNADSSDKTLNAPVPLRKRKMSEGDVLNLKKTCSTESIQVAESEEDRKEPDPIAVDYDTPLDLSVKNKITSTSSKPLAKRKNSVISVGSPSPSFQNASDSSSPPRPSILHSRVTMSPSSQYSNDSIHCYPSQVPVVLPRLSHNISERISPLPTILQPDISGDKTVPTSGMPPPPKILKQGNNICEECHIVFYKYDNYLAHKKHYCAFRQRQMSALAAAAASNQEQLSDDNNSNHSGVNESSTSYQSDDASKPSLRRTDHSVEPFRSVITKPSHSVFCCDACGVKFSTSDNLHAHQTYYCIKKPGSAMSKAAALRGDNAESPEGLESPFSGPEEWKCNYCDATCSSYETIRRHLTTHNELRGFRCIVCGYKGNTLRGMRSHACEHLNESTTSIEEFVTNNVIAENGAIPILPLSMDRSDDDSDHSKDSKTTWKKERAYLEKMRERSSLKRDTASIDHSEPNDSSNSPRLIERCPKRTCAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFW2</accession>
    <name>A0AAV4MFW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019702">
        <property type="protein sequence ID" value="GIX70926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16744" checksum="E02DF5A1C7B27D83" modified="2024-11-27" version="1">MLKEKHFGPALIFWTSRLAKTIRWLPTGLLKGLVLFDSVMGMERISMGPLILDYLIGSSEVGLIPSNKLIFPSRWGFSQEGAAPLPVGQREDLWVRGEHLRINENRSPPTFLSLLIASEGLQDNHWECLLEGLGLWLSYFISNVRLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIK1</accession>
    <name>A0AAV4MIK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_744551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002301">
        <property type="protein sequence ID" value="GIX72307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7630" checksum="4CE0291686BA7827" modified="2024-11-27" version="1">MTASDEPNAFISDSANNATTDGTVAIELMVDLVCQSDSSIIPAQPIVRVMTWQAKVTKEGFWSKPFLLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMH5</accession>
    <name>A0AAV4MMH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sn1-specific diacylglycerol lipase beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DAGLB_1</name>
        <name evidence="2" type="ORF">CEXT_419601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002384">
        <property type="protein sequence ID" value="GIX73174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12980" checksum="009E3A0EC6A2E9E7" modified="2024-11-27" version="1">MERGRCRLAWIAVIYVSFMENRSSCIQGGNFMFLNIFLSGLFIAISLNLILGALYVFFSRRGTISDPKPRRHVVTVTYVKLSAWILDLALAIYGTIVLYQDDFVTSVVFHPLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMZ1</accession>
    <name>A0AAV4MMZ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS12m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tko</name>
        <name evidence="8" type="ORF">CEXT_792771</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019824">
        <property type="protein sequence ID" value="GIX72149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000115">
        <property type="entry name" value="28S ribosomal protein S12, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX72149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="30375" checksum="CDD3AE1ECC9523F6" modified="2024-11-27" version="1">MTRGCLPKQIQRYLRLHSEVGGSEPAFYRHNLKRSFPRVSWGGLTFDPPFELNRRTSQPTEIFGQNLRMANLLKFCRSLHGIASNVASAAKYAMHNVAKCSTFPILEASRYSQNICNLRSTNKLGLVNKFLKPTIISNSVEQQRNGMFREISEDAQLYRIHFAKPKTKYKRKHPLDSRPQMSGHVLKTLVKHPKKPNSANRKCVLVKLSNGKTATAYVPGIGHNLQEHNKVLVQFGRVKDVPGLRLRVIRGKYDCGHVVKKSTTMRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPW2</accession>
    <name>A0AAV4MPW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_84431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002452">
        <property type="protein sequence ID" value="GIX73865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11474" checksum="B20560515ADCC1A5" modified="2024-11-27" version="1">MRRLLFPEPVTFPSGTRKDEGRSERCGNRIHILCFPFLCRKIDQAQVDVHNSTPILRRHVIDVHPLMDQVLRMGPLETHKGPRLLCFLARNDGWRTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRW3</accession>
    <name>A0AAV4MRW3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_557101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002479">
        <property type="protein sequence ID" value="GIX74171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX74171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16767" checksum="F7B5B66D39DEBE59" modified="2024-11-27" version="1">MRRLGRLKNSKDLNSKEKCGILEQSCTAYKFQCDVCKKHFTSKQALERHCKVHSKRTTNICEACGKLLVCSGVLEDEVVPSRNMCFRSEVSGKHAEDPSGRFSVSKETQRIVCKICKQQFSDSIAFGIHYHKHMKKTLVYCSKCLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTG3</accession>
    <name>A0AAV4MTG3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_204611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002600">
        <property type="protein sequence ID" value="GIX75593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10552" checksum="31D8E716AE36E173" modified="2024-11-27" version="1">MAKIGKRSASVLQAAVFVAIFSMHELSNPDNSNYQQRPYSDYLRYYSSKDPRLFNRNQIHYRAIIIHRHVHYLIQTILIAGMATQHSIGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTY5</accession>
    <name>A0AAV4MTY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_110651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002500">
        <property type="protein sequence ID" value="GIX74354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9169" checksum="95A152435D2B7636" modified="2024-11-27" version="1">MTFLMNAYGMYNLLNVNLEKVRFLLLNIFKTNDSSVSNHDCCSKAKTTTEHKQEEKMPISRQSFEYPTCSYEAAFCGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWE0</accession>
    <name>A0AAV4MWE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_460871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002649">
        <property type="protein sequence ID" value="GIX76085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7787" checksum="B60AA6E64515BDB2" modified="2024-11-27" version="1">MTTYKLSSELTKTPSGEHAGRFNSPTVEEVAIIMVGDPVDNRAIKITRRDSTVHVISDLHRSYDDYNIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY55</accession>
    <name>A0AAV4MY55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020209">
        <property type="protein sequence ID" value="GIX75914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="19206" checksum="62369CD8AEA3E6C6" modified="2024-11-27" version="1">MRVLYHWTTCGWFYASGPNASGKRMTLACRRFFPPVDFCTYSRLLTSTLHFALVVFDPNQRTSWPTNLCFLPIQTVIFNYTTVGGFETGFPLFEHLILYPTNHSNLMHEDFSYLETILLELFSMCEYTSADATQRLSQNKPFHPPDLLTLLQLIPLQSHVASDVLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYQ1</accession>
    <name>A0AAV4MYQ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_292441</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002664">
        <property type="protein sequence ID" value="GIX76452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053080">
        <property type="entry name" value="PP1_regulatory_subunit_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46899">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46899:SF3">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="8" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="9" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX76452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="231" mass="26427" checksum="6B8725BF457D806B" modified="2024-11-27" version="1">MDADVTPQSASTCLYQACRQNNVEHVKMLLKDGANINALDADRRTPLHFACDGGSIACLDFLLKMGADVHTPQSPLTPLHVACQEDSVECAEILLKYGANGAYDTIYRKRLLNKLRKIGVKDKMLNWIERWVWVCWNKVQSKFRQYKVGLPQGSVNSLSLLNMYVNNLTKRLKKTGNFQVSKFADHLVIWTEANNNWNYRSQQSELESAMNKALEVLQSWEIDNQMIINKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N334</accession>
    <name>A0AAV4N334_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_58312_1</name>
        <name evidence="1" type="ORF">CEXT_439151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002835">
        <property type="protein sequence ID" value="GIX78423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N334"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9898" checksum="9934A46C823D2505" modified="2024-11-27" version="1">MSSFPYEGGSTFAYESQSLLSLYNDNIPSAGNKAVWTIKSEEGKGRPRANIRLSPPCYSSSCVLCNGRYAGEIAGQVRHNHVHFQQLMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4K2</accession>
    <name>A0AAV4N4K2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_323131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020429">
        <property type="protein sequence ID" value="GIX78611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4K2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10551" checksum="290EA3CFBD597DD3" modified="2024-11-27" version="1">MVPKARIDNWQSELIGSQLAISLVVFRNLLYRYWNPSIDPTSLLESSIDPTSLLESSIDPTSLLESSIDPTSLLESSIDPTSLLESSIDPTSLLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCY4</accession>
    <name>A0AAV4NCY4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ig-like and fibronectin type-III domain-containing protein C25G4.10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_189665_1</name>
        <name evidence="4" type="ORF">CEXT_534451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003245">
        <property type="protein sequence ID" value="GIX82513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002602">
        <property type="entry name" value="DB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050964">
        <property type="entry name" value="Striated_Muscle_Regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817:SF73">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13817">
        <property type="entry name" value="TITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01682">
        <property type="entry name" value="DB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="226"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="336"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="434"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="523"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX82513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="80347" checksum="C69A27CED1BFC387" modified="2024-11-27" version="1">MAHSRWAVLKWSPPSVLPESVLSYVLYWKEVKMDEIVEYKVVNDVKSPHLLDNLKPKISVKPYTNKFSVILLHHLLTMYRYEVYVAARNEFGLSRGSTGVVFTTSPEVDEIEKEMEKLPAYNETACCIAAGLKTSCLDLCTYNMKMSDLQLLAIPCANQLEILVRCGAGGRDHSSCCQRRGIRWECLPICSAVLEMSPQAVVSTCIGDAGKIIQCMAEGVGQLPEAPEDLHTISVLPTRIHVKWNFRNTTSDPVWFEVRFTETQEKIPPHPLDYAYVENTTETNFALKELKSDTYYSIYVITMNEYGSSLASLVLLVHTPERDEIYNETIEASLGPPHSLEVTHQTMDSVTLSWRSPFHVPANSSLNYLVFFKPVNNSGDIEESSSKVATTNNYLTLSNLTVNTQYAIAVQARTGHQESPLSETVLAWTDPAIPAFVNPPVVVPPEPIVEGANVTLLCVATGMPVPVVSLFLNGQLMVQQQQSHVALVVPHIQHNVTKVDCFADNGLGQGAQSSTSLEVSFMPHVEMMDKRIPAEEGSSSVIRCQVSGHPEPRVLWYRDRKLRDPLKKGPDYDLDIKPHEDKLYTYMATLTLQQVATSHEGQYFCYAENQLGKDTVFVNLDVLPKFFNNASSCCAEKKVSEECRDACSVDIDIQQALNNPKCFKELDKLMYCAADGSDHRKCCRDNGIQRSCLRWCQGRPIINTQLYTPRIQDCQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDI7</accession>
    <name>A0AAV4NDI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF5641 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_94768_1</name>
        <name evidence="1" type="ORF">CEXT_167451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003232">
        <property type="protein sequence ID" value="GIX82395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="294" mass="33844" checksum="5B0D056730D5646E" modified="2024-11-27" version="1">MTGKYKRLSPTVVLNETKFEWALLGRFSNSFNSNDLINAMYVSVCDKVSDIKKAFSQIGLAEDDRDLTRFLWVDQLPNDQDNSMKLEILRMTRVVFGVTSSPFLLGQLLHWFCNASENAFGSVIFLRFTKDKKVKTAFVTSKSLLAPIKRMTLPRLKLMGAVVGARLINRVLGRDNPPDRLTRGVTIKDLENDELWWFGSSWLFKDYESVPHGGECFYERLVKCVKDPLRKISESALLTFEEVLTILQKIEAVRNMRPLTYTTNDLRETEPLTPDQFLHLERLNTAIHYTLLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NG45</accession>
    <name>A0AAV4NG45_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BACK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_117510_1</name>
        <name evidence="2" type="ORF">CEXT_675911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020903">
        <property type="protein sequence ID" value="GIX83782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NG45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022008">
        <property type="term" value="P:neurogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774:SF4">
        <property type="entry name" value="AXUNDEAD, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BACK" evidence="1">
        <location>
            <begin position="77"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="388" mass="44597" checksum="D79674D9F97E6298" modified="2024-11-27" version="1">MLDADMIEKRSNTITIKDCNPHSVKQFLRYLYMGTVDFNGWSPAVNLLKIAHKYSVQALISLCEAYLITTLVFSNACVLYELSRTYSLKLLKKQSQLFILEAGFIISATDGFFNLKARSLETFLGSSSFNMENEGSVLTCLREWAICECSRRCMTLSRSNVLSAMEPFLKHIRWAVIPEAHRTFIPSMLTEKFTENQPSLRRGFHVPASLQYHINYVKFVVELGAFHVPKCQRENTLCCLRFNVDNHVYMVGFRIVGLFSMNGRFFTDPCNLILSRDDNKTLIQFNLNSLSWTKGTASGKETWNEMIAYLPFPIRLDPFSTYSLTLKCRGNKDMFYTRWPRTRLDSEVISTDLGHIVFRVTGHCYALTQLFILPAPPYRNICNISNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHR1</accession>
    <name>A0AAV4NHR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RalBP1-associated Eps domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">REPS1</name>
        <name evidence="2" type="ORF">CEXT_542011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003337">
        <property type="protein sequence ID" value="GIX83496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15129" checksum="061808E0F9B3CFB6" modified="2024-11-27" version="1">MKISLQIATVIPAPATKTNDSPCSSPTDAAASPRSSTDKSWSFFHKDGSMNWTNFEEHHQLLGNDEENSERHSSDDDFDIWTITDEQRDYYINQFKSMQPDLKKKITGATAKEFLKNQNCLLLSCQKYGNCLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK88</accession>
    <name>A0AAV4NK88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_45601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003403">
        <property type="protein sequence ID" value="GIX84131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16074" checksum="DF0011BEA4D9554B" modified="2024-11-27" version="1">MRVIFRNRTINRLNTTNSTTNSLEPFHHSPKLSRTITTTWSIFLKKVRTPPGVGTHKCRPQSSFPCGQSIRRVHGSAVHSEWGGKREENSRKRDDLAMARKLYLCKGIAEQEPNLEPADGSAKDRGKGALIAGLERLGNVFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMI0</accession>
    <name>A0AAV4NMI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_811741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003449">
        <property type="protein sequence ID" value="GIX84734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18491" checksum="0248964BFD46CC00" modified="2024-11-27" version="1">MVLHRFRIDSIEPVSIPCSEIVYRKANDSIELEHAIHLEIVFGNEDIKISGAFHTSLEMVYKGNEFILLNSRALHLGDCFTGKNYLLNSGAFHTSWRLFRNELDSTWFFLVFHSFLEIVLYGKELILLNSGGLSSNFGYCFVENEFPGQRFFLHIILHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPG4</accession>
    <name>A0AAV4NPG4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_465571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003609">
        <property type="protein sequence ID" value="GIX86717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="16910" checksum="93D62564AC874B02" modified="2024-11-27" version="1">MSSALTSSEIFSKLIPDSELPSPEPNGNDPSGQNSEPLNPLEDVTALTSSEIFSKFIPDLKLRIAEPNENDPSRHVDVFGRVKLYLATHATFSRMIYSARGRNCRRLIAPHPSYLCQFVQPEGREGNGWAQDGGLAGLRKVPGDGWIKCGKASKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7F9</accession>
    <name>A0AAV4P7F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_93651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021621">
        <property type="protein sequence ID" value="GIX91859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12641" checksum="4081D8BBD573B5E4" modified="2024-11-27" version="1">MSGILLETTPGGMAVEETGEQFCDLIFVSDECLVTGNQVTVSMNYSVIDCQIHKYIEEDISLRSGDSDIMSQIVEKTEFCPNLDLDQCKWDFVPNSKECIRICIGLLEYECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7I1</accession>
    <name>A0AAV4P7I1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_210341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021702">
        <property type="protein sequence ID" value="GIX92550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7I1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10180" checksum="5755B046EAFCDEC9" modified="2024-11-27" version="1">MPRSSERERNESPFSDSDSDVTWIRKSQKRKSPRPKCLRGSHAIRTVVAIFHPHALTPIESWNDTLDLPSRETHFLGVRPRIGCHSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA40</accession>
    <name>A0AAV4PA40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-directed DNA polymerase from transposon BS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RTase_323</name>
        <name evidence="1" type="ORF">CEXT_3981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004314">
        <property type="protein sequence ID" value="GIX93946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="22301" checksum="31CFE3140ECB5BD3" modified="2024-11-27" version="1">MGSYRPIALTCLTCKLMERIILRRITFHLLNHNMLPQEQYGSRKGHSAIDQILYFVQRTLVQLSIKNFSKGQLLESTKTPTYLGFTLDTEVNCSKHINRLCEKGRKRLQLLKYISGRDWRADAGTLKITYTALIRPILEYGYQIYQVAASTNLKNERIQFSVARIITGLRHSCPNDIVCYETDLQPFTLRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAT4</accession>
    <name>A0AAV4PAT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_12591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004288">
        <property type="protein sequence ID" value="GIX93705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7886" checksum="15C3B3AA32EC025C" modified="2024-11-27" version="1">MTSLSPFSCGLPLFHKMESGFPISDLEARLRLLAVALALGVLDNISQSGFPESLTCFPPRNGNERGNDVLMCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTN5</accession>
    <name>A0AAV4PTN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_457261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005186">
        <property type="protein sequence ID" value="GIY00480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10078" checksum="E1E951C6709ED357" modified="2024-11-27" version="1">MYTQEELDVYCASFPKTNASSNPQIHAVMTTPRETDDGPEQSRLRRLLSGWPSIALICRATIGICAHSGKDETADKPPHQSQLAFGTRGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWE2</accession>
    <name>A0AAV4PWE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_194721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005144">
        <property type="protein sequence ID" value="GIY00110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13614" checksum="7540692F0EEAA7E7" modified="2024-11-27" version="1">MRFLANHGFFSFRVSELPDVDQIGGFGMNIGIRIESNGKKKKKKNLLVSSECRKEGGAYEIEGGEVRWNIEAESNGVLEVTAGHQADGRVAAGHAHRVLTCNTIRPTFNRIQFVKEDGHETSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXH4</accession>
    <name>A0AAV4PXH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_755321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005240">
        <property type="protein sequence ID" value="GIY00929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12070" checksum="0223677A10814D14" modified="2024-11-27" version="1">MRICGYRDSIHSYDETFFSERNSLDISTINPTTPSAFEPNLHQAGIQEDFPLFISEGPNHLARVAANAKGPKGMLLGGNILPLFCILGSIIEWRGILWGEENFVMLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3U4</accession>
    <name>A0AAV4Q3U4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_178611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005534">
        <property type="protein sequence ID" value="GIY03057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8353" checksum="EDE0E3D9A4CE048C" modified="2024-11-27" version="1">MTRAVIPKVTTFSGERPEQTNNKVFEKRENRVQNWKKTNLIEQTKKMRRITCQVADRISAAWFSRNENQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9R3</accession>
    <name>A0AAV4Q9R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNase H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_60975_1</name>
        <name evidence="1" type="ORF">CEXT_519551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005932">
        <property type="protein sequence ID" value="GIY06154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12227" checksum="64CE177F4DC6D75F" modified="2024-11-27" version="1">MSIEYKSTRQLSAAFDYLLCRLSGKANNQTALGVSRQIHATTYVETSSRSCPRSAREAFEVSALAALGKLNKNHILRTPLSTMSSRGKYKNKDVLKDDLRDRTRNCVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QD27</accession>
    <name>A0AAV4QD27_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atp6v1c1</name>
        <name evidence="7" type="ORF">CEXT_746431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005938">
        <property type="protein sequence ID" value="GIY06246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QD27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY06246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="25335" checksum="CAD29316B66C3357" modified="2024-11-27" version="1">MKVHISDYRQLDRNLENIEKQHTGSLWTRSLAGIVKKEHFVLNSEYLITLLVIVPKNLEKLWLETYQTMSDMVAEEVLDSDFEFREKQIEEEKDIEKNSPKPQESATCRPSEVDKGQFYCRILVLDPHQSDESFRGIHPPVWSHVQLPGYSSCAFEKQVPTSNLLNEKYKNLDSAGIRQIQRCARSISAHMAVTEYFPYVFLKLNLIFHLKKNMSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGW5</accession>
    <name>A0AAV4QGW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_252341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006236">
        <property type="protein sequence ID" value="GIY08365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17014" checksum="B074B88344A5716A" modified="2024-11-27" version="1">MLRVDLPTSTPTLRMDVDIVECRFLSCPVSEQPFMESAMAKRALSGSLDYPLMLQMAGIPDFRAIRSSLQVLQLDNSRLTQLRETTQASKAAAEHPHRQQFHRPRANDVFQLRTCSPYPHIYILFCSQTLLHRLIFYLLFPLYQLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNE9</accession>
    <name>A0AAV4QNE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_94581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006582">
        <property type="protein sequence ID" value="GIY10950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10879" checksum="D0A5543755C9A492" modified="2024-11-27" version="1" fragment="single">MAEEPEEDTSNQDDAVIPEKNKEEEGSSDTFEDSSPSEAEKSEAKMDERLLRHIFVRPRYAEPRHPILSSPYARHISLEAFGPKSQNGSMFQQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDF9</accession>
    <name>A0AAV4RDF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_52191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007665">
        <property type="protein sequence ID" value="GIY18711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043741588" evidence="1">
        <location>
            <begin position="28"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18632" checksum="289D617EB28C452B" modified="2024-11-27" version="1">MDTIWRTLYRVFMTALPHFILFPLLHVDTTVFSEASGGSSSSSLLSNSEFELAFTFARDAAIIAGTSFKSEVIEVDPLVAEYCAFTEEQKTVLFEEIPGMVIDAFMDMCSSFKERSRCKRFEQYLNCGIQEMEKYAAQVPRPLGSLVPDTADPTLTMSLKWPNHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RF63</accession>
    <name>A0AAV4RF63_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_798191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007656">
        <property type="protein sequence ID" value="GIY18648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RF63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="1">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11347" checksum="D020EAA88EC40BC9" modified="2024-11-27" version="1">MSSTEEKFTLIWKIENVSFTTKCLAQPILSPCFNLNSMDKTRWFLKFYARGVSSERFLSVWLCRDDKDSVQKQSVLVLKDILLLLMDHTNLQKKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGL8</accession>
    <name>A0AAV4RGL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_665101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007940">
        <property type="protein sequence ID" value="GIY20835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9867" checksum="55AA505424D03665" modified="2024-11-27" version="1">MQGIKGGWGQGGLRRFDQQLDRMGWCEGVRIRNEVPDGGPHEGRLSSRSLLIPGPKCHLRRAASVSRDPVFPRGPLPETLDPGGIKRDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRZ0</accession>
    <name>A0AAV4RRZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 3A29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CYP3A29</name>
        <name evidence="9" type="ORF">CEXT_169741</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008211">
        <property type="protein sequence ID" value="GIY22887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050705">
        <property type="entry name" value="Cytochrome_P450_3A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302:SF15">
        <property type="entry name" value="FATTY-ACID PEROXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY22887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="232" mass="26789" checksum="1155024C81B5AA51" modified="2024-11-27" version="1">MFGFDIYIWISILITAFVGYCTSVYLYVSRNDNYWKKRGIPFVPRMNMIKLMYLANRKPTNEVWKQDIGKYGRAVGSYEWNNPRFLLSDPNLIRDVLVKDFHKFHYRKEAGGRNTISQNAITALQGEDWKRVRTIISPAFTSKRMRQMGSIINDCSKSTIEVLETNSKEGKPVELFAAFTMDVIARAAFGTQIDAHNDPENVFVKHVKENFAELNMLQVLLYALLLCGCYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTV6</accession>
    <name>A0AAV4RTV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_370421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008458">
        <property type="protein sequence ID" value="GIY24865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14646" checksum="B709364F0D934B7D" modified="2024-11-27" version="1">MSTLTNKDRCLHYTNLSTTAIKSIFPKAESTIHATPNDEELSQAEYSPSKCLLPSRQAGGQHVPVTRGGGDFLHLLVNIVCCADPCRYPTFLFLPTMSTFSSYLFIFYGLYTFLRGSFFSGLAARRSNDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RU31</accession>
    <name>A0AAV4RU31_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_166623_1</name>
        <name evidence="1" type="ORF">CEXT_294971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008329">
        <property type="protein sequence ID" value="GIY23891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RU31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="23193" checksum="D15B5AE31C18BDA7" modified="2024-11-27" version="1">MLPSSQTPGQICWLWGNPLNNSIHVFEDKTSHSELCHYIKFMWTRAHVGTVGNETADAYAKMSTDKDTIDCRFALDRNFLNHLLLKYIMQQWQAYWTSSLKGREVFELCPAVNLKRLHGNFYLNQLITGHGALANHQKKVFQKDEVCSCGKAVEDRTHLILHCERWQDIRKKHFPKNFSQCSLLQLFAIKVLGQDWKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXL4</accession>
    <name>A0AAV4RXL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_254951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008494">
        <property type="protein sequence ID" value="GIY25121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15785" checksum="E6FF200EC4288836" modified="2024-11-27" version="1">MLLTENCGPSAVNYTSSSETSVAPPPSQFRTPSDLTEEYKSQLVSPEPCSQQLSNSSEKSDAINSLWAFSSFLEQHGPYILGDEWVFGKVCSVPLQVRKVRNHWTSSCITVEPNEYLHNVIVVQIAALGLLAETGDIHSERDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3Z0</accession>
    <name>A0AAV4S3Z0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_767001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008871">
        <property type="protein sequence ID" value="GIY27901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17779" checksum="E365932FFC5E7222" modified="2024-11-27" version="1">MEIQRSWYGAGTEVRTRAVVPLPIRKSGGCCYWISIREQLSTKARSSHRPDNSCARFQQTSTFHITLIKAPTVTRPVKTEAHKRWRHKLEIDVLPTLIHFQGRGRLLFVELGTSFASYEMEIQRSWYGPGIEVRTRAVVPLRIRKSGDAATGWEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S676</accession>
    <name>A0AAV4S676_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_473341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008825">
        <property type="protein sequence ID" value="GIY27528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S676"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18964" checksum="11B60AB52AE0ED42" modified="2024-11-27" version="1">MVTNDFSKRMVANDSSKQMVTDDPSKQMATNDPGKQIVTNDPSKQIVTNDSSKQMATNDQVNKLLRMIQVNKWLRMRIQMVTKDSSKQMVTKDSSKQMVTKDSSKQMVTNDPNKQIVTNDPSKQIVTNDPNKQIVTNDSSKQIVTMIQVNKWLRMIQVNKWLRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7P7</accession>
    <name>A0AAV4S7P7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_483881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009184">
        <property type="protein sequence ID" value="GIY30180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7P7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="201" mass="21902" checksum="4C5D1E3C33B44505" modified="2024-11-27" version="1">MEVDDEGCCASTGKSPPKGSTKVPVPPVPVSPLTTQALTSTTILTMAPTITKEALHCQKLLEAEKDLAHAKLKYDAALGFINLANIICDYELVDKMSTSKMTMEAFHLAEAAYKKTLKQVSDLGLCPLVNCSRHSSAKVKIVNKKTKRTAQLDEFIKPSKRQTAKLKVDSGNAKKDNLEIRNGFDQLTVDQPNDGDEQTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAL5</accession>
    <name>A0AAV4SAL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_156371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009310">
        <property type="protein sequence ID" value="GIY31024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10611" checksum="E90607FBC430FC31" modified="2024-11-27" version="1">MIEEPEPKLPPIMVRYTDNLKDQIAEISNQFEDDVRIKLADEQLKIFPANSDIHRAITKYLTDGKIEFYVITPKNQHPLKAVLKVSCQLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SCF4</accession>
    <name>A0AAV4SCF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_312821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009091">
        <property type="protein sequence ID" value="GIY29568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SCF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10328" checksum="4D204E4F4D8E58F6" modified="2024-11-27" version="1">MERLILLRKHFEQFKREDYASITRDWEYLSDECPLPEVKHFFETVLPIKVERELVLHFFDEGSTLYDDARETEETSVDAWMQDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SV65</accession>
    <name>A0AAV4SV65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_252081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010033">
        <property type="protein sequence ID" value="GIY36347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SV65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17407" checksum="D00B767E8E348B63" modified="2024-11-27" version="1">MTFILEKKDLYPTWSAASCFESPNELDLVQLQEGRSRKTPEATLKQHSTETKKKKKKKKNHKAKPHDTKLNGAQSGRSPTSSVVGTFHPLLQDPDDSRSMSRGWTGVDGHVQIFGIGLNNFALFVFPSFSLSLSLSPPLLSFFHPEDHEQVRGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVS0</accession>
    <name>A0AAV4SVS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_268431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010270">
        <property type="protein sequence ID" value="GIY38190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11989" checksum="E42211CAFB4AC0D7" modified="2024-11-27" version="1">MNINNKKGKDRLCGYHGNQFSVDIYLSEIPLSHQEGVGEEKKLRNRMETEQDIKFLAALMKLDKAAKRAEKHFSELGRIQTEHPQPSPSFLSFFLILLWGVTSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWE8</accession>
    <name>A0AAV4SWE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_323881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010207">
        <property type="protein sequence ID" value="GIY37702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10554" checksum="E89B175A6FE38808" modified="2024-11-27" version="1">MDLPQFYQLDETASEAFLGAIISKWNQKTELWRKTGANLALPSKCTTQRACYTASTRYHPYSEINSRHGILSFSYSSLFLSSNRGPYGLHTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1Q4</accession>
    <name>A0AAV4T1Q4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_195289_1</name>
        <name evidence="3" type="ORF">CEXT_64901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010354">
        <property type="protein sequence ID" value="GIY38777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043752789" evidence="2">
        <location>
            <begin position="18"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY38777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="376" mass="43385" checksum="4761AB3BFDC4B5B4" modified="2024-11-27" version="1">MVLLVYQLAVIFCYTELLPIPQWMDKSSSPQLCEIGNESRQEDSRCSEHQNKSYAQKSITDLQDKLKTGNSCTESRTYKLRNWKKGILNGNQSTRNPPEVFDASHIKPMEEIGDYNFAKIKDSETTKRYYFPYREKRLEEWINKEEDRPHKIRPQEFKFPENSRLHLPDSSDVTSSQNCDETMQPENSKDQTLPKSYSFPFRRKPLQTWMETPENRIENPEITSSMPHWRTIDGSMVEPKCKIRRSLSGSELIAEDPDSNTKYDKHKSFSQSVEISNVSNPLSGELSKDSPTAFDKIKLGFKNCVTKVKRDSFKTNAAKPVVKKRVIKKGIFQSKENICADLAQSCTSSKSLMNDHLNKMSLSPSYPGYLSFEKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1V4</accession>
    <name>A0AAV4T1V4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 8">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Ca3</name>
        <name evidence="10" type="ORF">CEXT_443461</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="BPLR01010445">
        <property type="protein sequence ID" value="GIY39331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1V4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00326">
        <property type="entry name" value="alpha_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018338">
        <property type="entry name" value="Carbonic_anhydrase_a-class_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF141">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00162">
        <property type="entry name" value="ALPHA_CA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY39331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="30081" checksum="A895EBA502405E36" modified="2024-11-27" version="1">MLMGKNVHTALRLISSLAVFSLSYTYIWRKEKIRPKHDPQLLQRPLSWTYVPKNCKSLLNTGEGWKVIVEGQDSCLIGGPLEHSYQLVQFHSHWGKCCSSGSEHTIDGKRYAGELHLVHWNVDLYNSVEEALASPKGVAVIGIFFQVGKYNEELMKLTDLLHDITHKGEECSLPKELDPAAFIPEVHDYWTYEGSLTTPPCHESVTWILFKKPVEVSEEQLEKFRNLYSSTVKAIVNGEPIPGKVVQNVRPTQPLNGRTIREAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2F8</accession>
    <name>A0AAV4T2F8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase 4 regulatory subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PPP4R4</name>
        <name evidence="4" type="ORF">CEXT_169391</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010501">
        <property type="protein sequence ID" value="GIY39742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2F8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008287">
        <property type="term" value="C:protein serine/threonine phosphatase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039918">
        <property type="entry name" value="PPP4R4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21467">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21467:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="470"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="540"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY39742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="709" mass="80262" checksum="95AFD68C2652430B" modified="2024-11-27" version="1">MCRQLDIVAKGIGLEATKSAILPELVELANDEETFVRLSAIETVVQMLPLLDDDTCTQAIIPLVKKLCENSFSSKDSTLPLVSKQLGQLCCGLAEVLHNYRQEKRNNAHVYLQRKKRSSICRPLPDLLPEVDHKDRFRECRRACAYNFPAMVLFIGSENFEEKLYNTFKDLCTDPFPSVRQTIACGFYEIARLLNSKASILEQELDSDKSSLVQSLIACEEVTSMTSNWRLHADFLSCLSCLPLCISSEIIFTTFVPLLFVKLHTARPIPCRTAAAYSLLIFLRNTPSLERRKGIISELIVELCCGRSCHKRMLFIRVCELVIELFSKVFFKLHFFKPLLILSADSVPNIRLRLCAILPRLKSLIKLPKDSHLLQQLESCIKTLISNEKDRDVSYAVSRAIEELDKIEVATEPISRRSSCIEIAMDMKDRLKEEEERHQLEMEFNSKLINERDSHSFAISTSAVKGGKIPVRKVSGTLPKQSKIKNGHPEQSEKVSSSQSKSLKRKILYPLKRFKTALATGKFKKERRISSPAVIVEFQKNPPQSLQSTRDVSTSTQNISKTSSPKCIIPKSGRSQSPNVRTWPRQKRSSSLIPKQSIDRCPSPMPQPRRFSEQSNKEISSEIQKKAISSEKRSLFSNNKVLQTAKENFTKLKFSSKESLSNKTPDTKKRSIGTILPSPEILRRSATLNNLNNESKIPAFLKKSVPKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TF84</accession>
    <name>A0AAV4TF84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_286851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011044">
        <property type="protein sequence ID" value="GIY43869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TF84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12600" checksum="1D4F766402389B2F" modified="2024-11-27" version="1">MTRGASVAGNGCVRVTTAAKNDEESNMARKYLILEFPPRSGVGRDISKQNESVPPQTFMEEEMWGLGEISLPNAQRGRFSVKMSYFTSTILDRKSILQVFLTYKCPYIDLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFQ9</accession>
    <name>A0AAV4TFQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPPP family protein CG45057</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CG45057_0</name>
        <name evidence="2" type="ORF">CEXT_608041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011111">
        <property type="protein sequence ID" value="GIY44227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001578">
        <property type="term" value="P:microtubule bundle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032273">
        <property type="term" value="P:positive regulation of protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932">
        <property type="entry name" value="P25 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932:SF9">
        <property type="entry name" value="TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="60" mass="6539" checksum="D6FA3C31D0515515" modified="2024-11-27" version="1" fragment="single">PTAAGGAVSRLTDHTKYTGTHKLRFDETGRGRGKEGREDKPNAAGYVQGYKDQGSYENTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIB4</accession>
    <name>A0AAV4TIB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_704071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011403">
        <property type="protein sequence ID" value="GIY46363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="22929" checksum="CEFD053944800A62" modified="2024-11-27" version="1">MQAKFDNIVNSSNSVPCGEEILLSWQIGCHVIDEELSLWAISLEALYNLGFHPPCWHTSGEHPQLFLYVRPIINNRPATFYKGLPPTLLQMPVMSCATENILRDRTMAARLHSRITKASANTSANTLNYVGRKKEGGSSIHWMPQALFPRARRLRRRDVTGLLQWPGRIVAGSGLDQRGDVPSFCACLYPNTIVYQFFITSANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQT8</accession>
    <name>A0AAV4TQT8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_44941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011772">
        <property type="protein sequence ID" value="GIY48943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10142" checksum="8DEC504C0C08CBFB" modified="2024-11-27" version="1">MSWVLGLLLETIANRAALESQRITALVNFSRWHGSWDRVVRIAAISTSNAVPRPTRTKFGGELDMSQVFRGMRRNVQLFLSPCTRVVPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TST9</accession>
    <name>A0AAV4TST9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_361231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011706">
        <property type="protein sequence ID" value="GIY48367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TST9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16255" checksum="7233E413D9B6D519" modified="2024-11-27" version="1">MNAKGSFEVFCIFNQKEFPFLQSRRSDQDKHTALHLHVLSSQGLQVSPDESQILHLQPERVSVSSEAAAPIRKTHSPTFACCLLNGWKYHQMTPPGTKAHPQKPPPPYFLHPLQNECFDKSPFERQLVNEKSLNGCTDFLLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U556</accession>
    <name>A0AAV4U556_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_119861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012301">
        <property type="protein sequence ID" value="GIY52865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U556"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="23113" checksum="D3D26DF9D0ED32AB" modified="2024-11-27" version="1">MIVERFVSQKDKGSRVLTGGEEDDGLQTAVLRRIHMQCLQLLHLLLEDADVVHEGDHPVGGHGTGVQPRGGKQGRHVEGHRALGGIQHEQLAPDKPQQRHLVGHLKVRKERDVPGPLHRTEEQPCGQLADVVDAHNVAGLHALRVPRGRVGFRPQQQRDEAGQVGVTVESVAIGQGYLSGEVVLGGGTRPRCTAVGQRKHLVVVPLWHRGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6L0</accession>
    <name>A0AAV4U6L0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_70101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012365">
        <property type="protein sequence ID" value="GIY53414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6L0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="11769" checksum="7691F7990B874F0C" modified="2024-11-27" version="1">MSSVCAYHLDAVLLDPYLLKPKSHSTIFRWRSHAVCLPCCSCTAPAPPSTNTPAHVTLPSRSNQSRLPQPIFNLYPHPVNPAKKGAFAGAMRAGEIILGRGRNSPPPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBQ5</accession>
    <name>A0AAV4UBQ5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CB1 cannabinoid receptor-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_333221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CNRIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012622">
        <property type="protein sequence ID" value="GIY55241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031718">
        <property type="term" value="F:type 1 cannabinoid receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029204">
        <property type="entry name" value="CNRIP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31952">
        <property type="entry name" value="CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31952:SF1">
        <property type="entry name" value="CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15043">
        <property type="entry name" value="CNRIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY55241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18621" checksum="B0CFA0E83CC5CBDB" modified="2024-11-27" version="1">MSKDISKYSLTVNIKRDDGKALVYYKQDGERFESNCTIKMNVETTYKFLLNFRPPLKIKSGSLKNSGLEVKEEGFTPEASSYSLLWTSNDVVVSKNKGRDHFTLSLTVQDLGILEIPLQLKFYSANDKSHSVWGNELHHIEYDCIFKKDLFSFSIEKEMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UC45</accession>
    <name>A0AAV4UC45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_597881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012631">
        <property type="protein sequence ID" value="GIY55328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UC45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16339" checksum="15C702822F966B3B" modified="2024-11-27" version="1">MQFLMFTDAAVDSLGEKLSANRVFVRWKESSVGEVNAAIMCPITMVYCKCTARRIKAIKAQNVVKRQMYESSNKMLTFKNYGTVNAGTAAIVVISDLATEESWDACLSWNIYATRNRVEISSNVHDETNEIATALNQDASCRRLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDG9</accession>
    <name>A0AAV4UDG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E3 ubiquitin-protein ligase UHRF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Uhrf1</name>
        <name evidence="5" type="ORF">CEXT_212871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012673">
        <property type="protein sequence ID" value="GIY55775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF27">
        <property type="entry name" value="OS04G0289800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="105"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="266"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="287"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY55775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="331" mass="37638" checksum="35FCC2D39491F91E" modified="2024-11-27" version="1">MDYLELVIKQKQENLEKLESLGVLNLRKSYRNDLNQSPSKKSLKGVGKTSKPKFKASEVLPRRRSGRLLQKEPSNYLEENIDYFNESKLSSPNKHIYIKRENVFGAIPDVPVGTVFLTRMEASRAGIHRPPISGIHGNPAVGCYSLALSGGYEDDDDLGDTFIYTGEGGRDLKGTKANPKNLRTAPQSKDQVLQKGNLALSKNVENNLPVRVLRGYKLRSNFAPEEGYRYDGLYKVVNYYITTGLSGFKVFKFHMERIEDQEPSPWADNFKIKTSNNVTSVDKENISNDDEDQQTNDENEDQQTNDENEDQQTNDENEDQQTNDEDQLQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKY5</accession>
    <name>A0AAV4UKY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoenolpyruvate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pps_12</name>
        <name evidence="1" type="ORF">CEXT_236551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013058">
        <property type="protein sequence ID" value="GIY58434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051549">
        <property type="entry name" value="PEP_Utilizing_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615:SF1">
        <property type="entry name" value="PPDK_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="488" mass="56061" checksum="04B5BCE9A137C4F6" modified="2024-11-27" version="1">MTVVELISMEGFGSPYSNALMMGVFGRILDDPDLLNYATERTSLIKVTKMPLKSRLKAYWYLFSFDFGYHEVKNKIYNYPLKFLKLKTAKETFTALINSCSDFDDAAHFHMQCSDGSQNWNMSILKTLIKAKEVKIDNDIYSDFARLLAASSNVESANIPQVLQEMAVQIVNDISCEKFKSMSLEEALEWLQTTNMPSGDTFRQFLKRHGHRCIQESDVRSITWEMEPKSLVKLLQNLAGAGKEVAKNKNDIDKVLSELQVPLGFISKCYLRFVLPLCRRGIRGREAGKAITMKAFDHWRKGYRRLGKAHGVRGTSSPDADLLYFFTLEEVKELLETRSPGLISKAIHRRKMYPTLEKNMYSPEIMKRTSETCKHTVSQGVTKGYARVCIFRRGGHLKPGEILNHPQYGYRLESLLPHCFWVLLKMDRWLYACRRAQVRIFGRRSVVHVFMSEESRLQGFDSQIRPGQASMVNLPTGSYQDSFFHMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT82</accession>
    <name>A0AAV4UT82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_1151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013402">
        <property type="protein sequence ID" value="GIY60946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11161" checksum="DD6E33B7D7E2DE85" modified="2024-11-27" version="1">MPKYSLSSTKDPEQQEAPDAKKEKAHPHFPDHWSFSRSGPFGASGSTHGCGPKGTLSLLGHIEKGGNGLLVEQQNELRPTAQRGTIERRTQLETPSIEVKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVG2</accession>
    <name>A0AAV4UVG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_32803_1</name>
        <name evidence="3" type="ORF">CEXT_404791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013528">
        <property type="protein sequence ID" value="GIY61827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY61827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13464" checksum="71646C970556B014" modified="2024-11-27" version="1" fragment="single">MSKSVGECFELCDAAHPCQNGGTCPEGGACDCPDDYMGAWCEIPKWCVPGRCGYAEDVMCDWDKENKTGICKCKKEKYQYVEKTRECVECDCGENGDCFLQDGMKVCVCNELRRQLSQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1Z3</accession>
    <name>A0AAV4V1Z3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_580931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013815">
        <property type="protein sequence ID" value="GIY64028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1Z3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12164" checksum="DEDA2F7B71A84626" modified="2024-11-27" version="1">MGFSQVVVRGHRLESGGRGTLPQLPAHGGHLLHHLHHHHRLLHGQHLRRFCHRHLSERGGAGVQELRAGQESEELHRVRSQSQTGEKVYSQSEDTIQNMVVRDIPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6Z2</accession>
    <name>A0AAV4V6Z2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">palmitoyl-protein hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABHD17B</name>
        <name evidence="12" type="ORF">CEXT_213091</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="3.1.2.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endomembrane system</location>
            <topology evidence="9">Lipid-anchor</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the AB hydrolase superfamily. ABHD17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01014061">
        <property type="protein sequence ID" value="GIY66010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000008">
        <property type="entry name" value="Alpha/beta hydrolase domain-containing protein 17B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="11">
        <location>
            <begin position="90"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY66010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="32110" checksum="5289867F09316CDC" modified="2024-11-27" version="1">MNGLSFSELCCLFCCPPFPSRIAAKVAFLPPEPTYSFVPDESGTKFTLNLTDRAEWQYSQRELEGTEVFFTRTPRGNRIACMFVRCTPNARFTILFSHGNAVDLGQMSSFYLGLGSRINCNIFSYDYSGYGISTGKPSEKNLYADVDAAWHALRTRYGISPENIILYGQSIGTVPTVDLASRYEVGAVILHSPLMSGMRVAFPNTKRTWFFDAFPSIDKVPKVTSPVLVIHGTEDEVIDFSHGLAIYESCPRAVEPLWVEGAGHNDVELYGQYLERLKQFVSMELVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9N5</accession>
    <name>A0AAV4V9N5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_553511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014185">
        <property type="protein sequence ID" value="GIY66997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12005" checksum="0B1867FE070DA7BF" modified="2024-11-27" version="1">MLMGLGRWVALGRALCSLHSTPDNPLFAGGGQGGSRICKRIPLFNRFSITVSNRGGFFCFPAGVYDGAILAKRVRQTHRNKEKSCVFIGFVGSRRQIGFRFRRVSRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFD6</accession>
    <name>A0AAV4VFD6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HNAJ_LOCUS11396</name>
        <name evidence="1" type="ORF">CEXT_391351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014481">
        <property type="protein sequence ID" value="GIY69066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="14786" checksum="A4388278581C5535" modified="2024-11-27" version="1">MQPITRDELAYALRSLNSGKSPGGDGIHSEFLSHLGPNSFETVWTFFNLIRNTGIVPAEWRTSIIIPIHKKGKDPNMLQNYIPISLTSIAGKAMEKIVVRRLNYFLKLTDLLLRSRRGLEVPDLLINMLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VIQ3</accession>
    <name>A0AAV4VIQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_594261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014542">
        <property type="protein sequence ID" value="GIY69499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VIQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10525" checksum="E08ABBC972FE263A" modified="2024-11-27" version="1">MARGECFIPVGGIAKCHSMFDVRTRWRLFSNVSQSLSERNKCSSAAEFNHHPLGVFQNEKNYLFPPPPSEGTTSLGGQPPPANKEGGRRRNGRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VK57</accession>
    <name>A0AAV4VK57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_704011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014610">
        <property type="protein sequence ID" value="GIY69918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VK57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13775" checksum="D14D69B56DB147AF" modified="2024-11-27" version="1">MQACLPKIGSLFKEFLNMTGQRLHHSGIARSTQHNEAAFQNTVDWKLILRTVYDIPRPATIENAYMAAAHGTISERLTIFCTHVFYNREINKYLKLRAQATHGCLIISPGLFSIQSTIKFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUK3</accession>
    <name>A0AAV4VUK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_222091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015142">
        <property type="protein sequence ID" value="GIY73946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11202" checksum="93C3FFA9869C7D22" modified="2024-11-27" version="1">MSNKHGEGNRLLLCTGCFGSSISDNVNNVTSNSKNKDSDLYQVYHVIRTIVHGSTTTPCNFHAPMIFCRIRMRIVSLSQYCEWLTASSVVCENSTPSPSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5X4</accession>
    <name>A0AAV4W5X4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_96151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015536">
        <property type="protein sequence ID" value="GIY76830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5X4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16399" checksum="95651B97432A4D76" modified="2024-11-27" version="1">MINTKPLQPPMEKECVLVEPLNSLLHLATLNDILRWQWCLSLLVADFNSRVICQRQPGPSSFLTKMFMGWVSVAFMEGGYRNFSFFCLLQSHGPNERSNERLVGVGEGKGWVGTGFLHYRSEWFPLWHNSGSYSFSISLLCHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W670</accession>
    <name>A0AAV4W670_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_605821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015672">
        <property type="protein sequence ID" value="GIY77743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W670"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13320" checksum="7DCD2EC7760AF5A4" modified="2024-11-27" version="1">MEDLIEYGIQNPNPFKPDMIPFITEHFQETSSFHPNTSYMADSENSFYSDKSVAAKEIIDAQVGSNNAHLQSDKVNAEQNSPFTEQNGISYVNNGFLLSSNTSKSSTVISVKNKQIYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WB68</accession>
    <name>A0AAV4WB68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">X975_06096</name>
        <name evidence="6" type="ORF">CEXT_160911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015890">
        <property type="protein sequence ID" value="GIY79449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WB68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01450">
        <property type="entry name" value="vWFA_subfamily_ECM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050525">
        <property type="entry name" value="ECM_Assembly_Org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24020">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24020:SF20">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00453">
        <property type="entry name" value="VWFADOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0768">Sushi</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043876166" evidence="3">
        <location>
            <begin position="31"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="54"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="5">
        <location>
            <begin position="350"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY79449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="413" mass="44494" checksum="464DEAF82ED8FE97" modified="2024-11-27" version="1" fragment="single">MINNKPKNFISLNGKVLIFVFFVLISSCSGSSIKEENDIVEYLEKNNILVGKAEIVFLLDRSGSVGAANFETEKGFVESFLTHIVVDANASHVAVISYSDAADRHIDYLIQPKTKCHLSQELQDVQFKDSRATNIAAALDEARAVFQNARPQVNKVLILVSDGRANMGGDPVPHANSLKELGIEIFCFGIGSSLRGELERLASSEQHVYNCDEFRDFARLAKRIRGDPHESSWSGQAAAPNCDHLCDSPYKGEADDPGCCDHSARCSCALLSGMHMCVCGPGYYGLSGLAGHCRACPIGTYKSRLEPAKQCTPCPPGSTTAKSASGSIRDCVCKEGYEGNPTSGLPCSPVKCPPLQKPKHGFTLGSCRDSAVPFGSDCGFLCDQEYELVNRDSAIRTCLSNGSWSGKSAVCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCH0</accession>
    <name>A0AAV4WCH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_342391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015902">
        <property type="protein sequence ID" value="GIY79544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10057" checksum="C82C8163B38ECA47" modified="2024-11-27" version="1">MSWPVLKSDGKCSVSWIMNNESVTFQVRKINYEWVTWAGDQVMKRSTSMKWPFLRETFERNDISRVIYSFLFFFAKVKGGVSAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WG09</accession>
    <name>A0AAV4WG09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Endothelin-converting enzyme 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Ece2</name>
        <name evidence="12" type="ORF">CEXT_137421</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016160">
        <property type="protein sequence ID" value="GIY81732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WG09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="11">
        <location>
            <begin position="113"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="10">
        <location>
            <begin position="564"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY81732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="765" mass="87837" checksum="EC8AEDD9B30ADCE2" modified="2024-11-27" version="1">MQNNKGSGDDEKTEPKENDKWMENNDHDKDSEMTPKNSRLDDLRGRAKKFASNRYHLIIVLLCIFLFILFLIVIVLAVQLGTYSCQVSVECRTSECLVTAAAVVERSDTSVNPCNDFWAFSCNGWKTRNSLPRNRGSFSVSDQLKQNTNMKIRQLIDLVPHDSDTAAPQRKVRSFYDSCRDLKEIEHWVPTKIKQAIHEIGGWAIINDTPSHLWRRNDVLKMLQVTYGVEPFFKVLVEADDTNPMKNIIKLVPSGLGLPAPSYYSKPHDDKYVQAYKDFIMNTVQTMDVNLFESRRFAEEVFNYERRIAEITPSPEVLRNTKDLYTILTLERLDQLSHSISWTEILQMYFPNSVTPDTKVAVLSQDYFNKISEIISSTDDVVLNNYYMWRLMHTFAPHSSAKFRLVANKFKQTFEGTKDLGLSYEDNWEACIEITSKFLGHAIGSMYVDHYFPQSKFDKVHVYVHKLVGALSEVYRSIPWLRDDDVREAVQLKIRSLGLFAGYPNFVRNHTTEYYKELKVQAEYFQNIKEGVYFLHKKQEEMLKNKAMPDYSWTVFSHEAVAEYKYAGNQLVVPAGLFESPLFHENAPLAVKYGVLAAHVANKLAEVLDEKGINYDEYGTLRQWASNSSVIAFANKETCLKKIISNYSLEEVRVIPELTVGSLIADIGGVKIAYEAYKRHSAEENENAELPGLDINNQQLFFISYAQSLCQIIKPEKLMSLQEASTVLPEELRVLGTLQQLPEFSDAFSCTRGSVMNSQKHCQMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJA0</accession>
    <name>A0AAV4WJA0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">valine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VARS2</name>
        <name evidence="9" type="ORF">CEXT_526021</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01016271">
        <property type="protein sequence ID" value="GIY82712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF71">
        <property type="entry name" value="VALINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="8">
        <location>
            <begin position="54"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY82712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="293" mass="34003" checksum="AE9DB401E3B9C943" modified="2024-11-27" version="1">MLSANKHNFPNGIPECGTDGLRLSLLTHDIQDQRINIDVKSIQEVLNLNENNMDRWILSRLARLVAVSNTHFEAFNFHLTADAVRKFWVQNFCDIYLEYAKPALLESQERRLLVCRIMLTCIETFLKIISPMMPFLSEELYQRLFFMSNIEHHPSISLAKYPTADKYLGWRNAVLEADVLTVTDIISITRSLKSKHGVTRMKPAVVIAVEEENALEAMNPFSNLMVLLAKLESVTFHLTQGQEFFEQYPQDSWVFEKWDHGITVIMDIGEKPKPRKAIMVLKRWIKFDRICQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WK11</accession>
    <name>A0AAV4WK11_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_43041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016235">
        <property type="protein sequence ID" value="GIY82321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WK11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043988634" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="8318" checksum="FA9A15C0F0A53F69" modified="2024-11-27" version="1">MRKHKTKSFAQNLIYIVLLFLLIKKQRGPVGDLDCLRAPVEVVQPQACATTVLSSLPLRETDRKQITCPYLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WL30</accession>
    <name>A0AAV4WL30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_639111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016405">
        <property type="protein sequence ID" value="GIY83620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WL30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15499" checksum="D8EA6BC6A36929F9" modified="2024-11-27" version="1">MGRGELPPILFSGEENVEGGKAGSDLHLRYVCVHWKGVKKGEERSVVCCSSHFVQKMNGGECELIEAIEQGVWISKRTLLGWVDKQRPNKWTRLYKDREPRKLIKKSDCCSHQSSSAEDLLQQGATEREGACGRCHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WU92</accession>
    <name>A0AAV4WU92_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transketolase</fullName>
            <ecNumber evidence="8">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">Tktl2</name>
        <name evidence="16" type="ORF">CEXT_212281</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01016734">
        <property type="protein sequence ID" value="GIY86066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WU92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019682">
        <property type="term" value="P:glyceraldehyde-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000129">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000033">
        <property type="entry name" value="Transketolase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051424">
        <property type="entry name" value="Transketolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43195:SF1">
        <property type="entry name" value="FI06132P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43195">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="15">
        <location>
            <begin position="313"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00016662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY86066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="588" mass="62887" checksum="9C7AB4F8D4C11739" modified="2024-11-27" version="1">MGVKTMQDLKDIANKLRINSIKATNASNSGHPTSCCSMAEIMSVLFFNTMKLKISDPRDPSSDRFILSKGHAAPILYAAWAEAGLFPESDLLKLRKIDCDLEGHPTPRLNFVDVATGSLGQGLSCSAGIAYTGKYLENASYRVYCLIGDGESAEGSIWEALSFAGHYKLDNLVAIFDINRLGQSEPTMFQHHMDVYENRLKAFGFNTLVIDGHDVEQIVKALENAANFKGKPTAIIAKTFKGKGLAGIEDEENWHGKPLGAKADNAIKELLAIIANNCPPPQATNPPPNDVPPVDNSPICLSEPPTYTLGDMVATRLAYGSALLKLGTNSKRINLIGVAVGCSTRGRKIPFTSTFATFYTRAFDQLRMAAISQANIKCCGSHCGVSIGEDGPSQMGLEDIAMFRTLPGSTVFYPSDAVSAERACELAANTQGICFIRTSRPNTPVIYSNDEPFAIGKAKVVKKSANDVAVVISAGVTLFEALKAADLLAQQGVNIRVIDLFTVKPLDVATIQSNAKECGGRIITVEDHYNEGGIGEAVAGAVSCCRNTILTRLAVSGVPRSGPPAVLLDMFGISANHIVKAVLEIKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYP5</accession>
    <name>A0AAV4WYP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_632061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016939">
        <property type="protein sequence ID" value="GIY87463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15357" checksum="E8D344D2BE1D76A3" modified="2024-11-27" version="1">MLRNPHFCPPNSRVFVSTKVSIASGSFDSKVFAEDLGSECLRWHGWWVLHSFLNFSFKIMQIINKRPDSTLNWEWRTHLTFADTEELLCVDTSLNFLLFSREPSLLYPNARVFFSTKVSIASGPFDSKVFAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0D0</accession>
    <name>A0AAV4X0D0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">28S ribosomal protein S18a, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_22487</name>
        <name evidence="3" type="ORF">CEXT_521141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017002">
        <property type="protein sequence ID" value="GIY87984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0D0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF66">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY87984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14483" checksum="8C095E6FF60331ED" modified="2024-11-27" version="1">MRQFSLTAPSYLREVKRTETENQIVIEGVKINSEREGKVLNLQNRNGCPLCRIGVYFLKHTDILIISQFLNSDGSVVPQHITGLCNKQHFRVVRAIALAQRAGLIPKKSGTPVFGGWEKYNTYFKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0H0</accession>
    <name>A0AAV4X0H0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein phosphatase 1 regulatory subunit 21</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Coiled-coil domain-containing protein 128</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ferry endosomal RAB5 effector complex subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">KLRAQ motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ppp1r21</name>
        <name evidence="11" type="ORF">CEXT_673811</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Early endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017025">
        <property type="protein sequence ID" value="GIY88138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0H0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040024">
        <property type="entry name" value="PPP1R21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049372">
        <property type="entry name" value="PPP1R21_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019343">
        <property type="entry name" value="PPP1R21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019348">
        <property type="entry name" value="PPP1R21_six_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21448:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21448">
        <property type="entry name" value="SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10205">
        <property type="entry name" value="KLRAQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21636">
        <property type="entry name" value="PPP1R21_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10212">
        <property type="entry name" value="PPP1R21_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01254">
        <property type="entry name" value="KLRAQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Protein phosphatase 1 regulatory subunit 21 N-terminal" evidence="10">
        <location>
            <begin position="12"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="139"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="545"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="630"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY88138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="714" mass="82442" checksum="5F03DFC248C2497A" modified="2024-11-27" version="1">MEENSEVVLKYQKLALEYSKLKAQTSVLKNAISEEHVVVQDLQETGKKKDQLIRKFEQELECLTFRNVQLSKRVSVLQGELDAADSNAKHSKSKHSPNISAPLSESYNILNMELQSRIEENEKLHQQIYAADMEQERAISELTSTIDSLKSKLANQEKKFSEKIAEQESLINNLQKDKIKMQVSIKNHEQEMKDRKKTEETKTQDNNFAKEDLTFQIEEAKKVIAEKVLFNDRYKDALNIINVPVIQREKHELLSSLMLKMHGFISDFCRQLSDLHTFMIQRLCLKSDDSATKTAISKNLKAIPTSFECIVNAIKSETLTWDKSSIMDFCDTFQKYEKNLNKLLPFLILRIQDKDSWTAASSKIIELVGKLVSLSRKLMACFKKLYRYILLLAVVGSAEKNQYYITQATIIKKILSNIDLLQQLFEEARKMFGSKIALDHQMPMLSQSEKTTDECILATLVSLSLTLKRITDLMEKDIDSFSSNVWYKPRNALGFKTATSNPCVWQYKERGSKYIQHISQVESSSIPYEVALKNWQTLCEHTDNQENLTQQLEQYQNKVMQLELDKENWMLECQLLRAKVSQDPDATNINIESKSQDYDEIHLYVKNTVNQLIKQIQFADSKAITFKNECETLHQKLKLSIQKKDELENEILSSRQVMDQMKEEQKTLVQTYNEQLNTMSEHLANLNETLTAQKDEIDALKQAGTKGSKKGKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4A8</accession>
    <name>A0AAV4X4A8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_663671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017077">
        <property type="protein sequence ID" value="GIY88589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4A8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17375" checksum="B9C713D7701A5B7A" modified="2024-11-27" version="1">MTQCLWLSFLSDAKDEWTALIILFLQLWIYINLFRSRTRIHLLTNNLERISNMIRVDTIQRKDTLKIYIWVYCLLVTCWTACFEVALFNSRMIAYDQHRLRKSEFIPVYLKEHLVVILKGAYAFMFLVGNGFSSQCCLDIIALHVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF79</accession>
    <name>A0AAV4XF79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_801611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017680">
        <property type="protein sequence ID" value="GIY93596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11969" checksum="69CB62437B9BFCD6" modified="2024-11-27" version="1">MCCLRSTILFMVSQQFPIWITPKELLSEIFELTDEAEKERLRKYYATFAPLFYSWVLQQFYIRITPKELLSELFELTDETEKDCEIEKICNLTAMNGLPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJV6</accession>
    <name>A0AAV4XJV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_199621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017845">
        <property type="protein sequence ID" value="GIY94937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="349" mass="40786" checksum="53B87BCC7072D639" modified="2024-11-27" version="1">MAIDSNMQYLVERLQGKISYLYGYLKETKVLVNTSDEITEEFITLLAKAIWTKATVHDKVWKDFISKFRERLYHELDVYLKYIIYACIAVKNDTRDIFKCFLYVCTVVFGICINFCRHAHIYFFKYTPIILNVIFSFLFRQQFYKLGGFKELLKHISIQKPVLLHHDIRKITDVSPDSVKSLMVTEEFDAYFPQTLESIQPRVVERHKQGSFLASKILKLKQENPESVWKSFVDAFPLLIQASPRVSGKFMLRNSLGYKVILTSVYLFETTYTIDPISSRKANEEAHNILLIKTSSQSSDTCKKDVMVQGHERKMIQRQVSEMGKGRGLLFSDMHLLKLTKYWQSVCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKQ5</accession>
    <name>A0AAV4XKQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_31171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017769">
        <property type="protein sequence ID" value="GIY94323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13959" checksum="4D0889A9ACE04BA5" modified="2024-11-27" version="1">MQSPQFVSPHAKTIHAFTSLEPLVFEHHPHTQAPQAKLHNKRRLPGKNRRSPLFCHCMQKGKQKPKKHRRKFLFSSELATHPLIRPPTTSMSTHPALYHYHLRNTRNFLLLQVEPAIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRP7</accession>
    <name>A0AAV4XRP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spindle assembly abnormal protein 6 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sas6</name>
        <name evidence="2" type="ORF">CEXT_68641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018062">
        <property type="protein sequence ID" value="GIY96569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="203" mass="22229" checksum="03519507D2DB58FF" modified="2024-11-27" version="1">MKLLINFSVKFSLAMRSEAEEFSSFKTRAKSQCLTNRFLRSFFSVIKYLNRQLTDRCILPQYIPPSNLMISPSQNSAGTQVVKATTSGGAGDATHSDKSKSIPSRRKIQGLSHISAEMVIILHLMEEIHNSPYHIPADSAYISAPTCTARDKNASPADTNVIAPNFEIDSAALSAAFGSEQILKHSTAKKSIGGRNKIALRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRV3</accession>
    <name>A0AAV4XRV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_411221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000833">
        <property type="protein sequence ID" value="GIY97781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12388" checksum="2DCCA2DAE0BF6942" modified="2024-11-27" version="1">MCKPKCTACKVADLIFITEDKIKKNYSFREELLINLTLKSLQKKEKKLKKRRKQRKLSWESIKLICQPRIDYSQLPEDNDPLGLNDLYSNLKLTSASNKEDEKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUA0</accession>
    <name>A0AAV4XUA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_691031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018328">
        <property type="protein sequence ID" value="GIY98722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11418" checksum="DDB03E01F2B034F3" modified="2024-11-27" version="1">MSNQASCGRAPELLKMPNPPLEGTQKGDVYSFAVIAHEIVVRQGVFYTGNDASPKEIVENVMYGTKSAYRPLIDLDNCDEGVIQVIKSAGQRSLMTGPTSKPSSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4V8</accession>
    <name>A0AAV4Y4V8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">Acylphosphatase</fullName>
            <ecNumber evidence="2 5 6">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Acyp2</name>
        <name evidence="9" type="ORF">CEXT_87762</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5 6">
            <text>an acyl phosphate + H2O = a carboxylate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="2 5 6"/>
    <dbReference type="EMBL" id="BPLR01018635">
        <property type="protein sequence ID" value="GIZ01194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4V8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000011">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10029">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10029:SF3">
        <property type="entry name" value="ACYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="Acylphosphatase/BLUF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="8">
        <location>
            <begin position="10"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIZ01194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11778" checksum="A050A40DF1F115A7" modified="2024-11-27" version="1">MRNILKMIQSLDYEVFGTVQGVFFRKFTRDKAKELSLKGWVMNTSQGTVVGTIQGKEENWLRSVGSPMSKIEKCVFKNERHITKEEFSDFFIKKGDKMYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4W0</accession>
    <name>A0AAV4Y4W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_154451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018790">
        <property type="protein sequence ID" value="GIZ02277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8088" checksum="A47740D4729BF2B9" modified="2024-11-27" version="1">MFSSGAKLDQQVALQFRFGEIFENFRDFPNFLETLKSKEFSVSVVAIVSAVIEITTMALSTLQSLCQQHIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4X4</accession>
    <name>A0AAV4Y4X4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Malonyl-CoA O-methyltransferase BioC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">X975_02098</name>
        <name evidence="6" type="ORF">CEXT_529591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001265">
        <property type="protein sequence ID" value="GIZ01209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4X4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 11" evidence="5">
        <location>
            <begin position="90"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIZ01209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="318" mass="37526" checksum="D3D09C98BD083A83" modified="2024-11-27" version="1">MLQKGLESKLNLFNRAGVTIILLMIRAMISSKLKRQCFSFYFYLFLFSDNCVMYRLPKLIAFPHRRPDEYYKDLQERPGWKDLDGEVVMDVGCGSGRYSTINILKYYPKIEKLIAIDNYTPSIYFASTRNTESKIEYRLADIEDRSTLEKWEGKISKIFSTNCFTHVDPEKAFRNVHYLLKPGGEAIITFVSKSQYYDIFLDVILRKEFKEYSAPIATYPRALRQKLDASDYETFLKKSGLTKIVCEDERQLFFHENIECCFMAIRHCNLASDVPRIRRDEFDQDFSQEFLRRIEPDPDDGRFYVKFTVVKIIAKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4Z0</accession>
    <name>A0AAV4Y4Z0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_252111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001397">
        <property type="protein sequence ID" value="GIZ02108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13873" checksum="2D0D3310A17179C7" modified="2024-11-27" version="1">MSRTVYLMTLSRGPLDLEEPSTCQTPNYIVPQSSADSFEILMILFYWREKIRFHQGMDGEIVGMNRFGVHYVCPWEFFLVAFCLDLLFVVDSFAEVVEKMLKWAVVNTLGVVDANVKFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y560</accession>
    <name>A0AAV4Y560_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_50401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018784">
        <property type="protein sequence ID" value="GIZ02253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y560"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="38" mass="4167" checksum="7CFD968B14213B4B" modified="2024-11-27" version="1" fragment="single">RQFANHAKFPYSDIEHELGCTASIVGADINVDIARIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFR3</accession>
    <name>A0AAV4YFR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_550661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019159">
        <property type="protein sequence ID" value="GIZ04866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12257" checksum="A40593EFD8324AA1" modified="2024-11-27" version="1">MGIATTTATEIELLSPSLALQAAVCTTAEPGPGADARAKVGPIKVATCTVFVLFLIFCSTLLQISRFSHHSLLLTRIMVRMLLSGAYVYVARLFHFCGIRLLDFVSLSWLPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M912</accession>
    <name>A0AAV4M912_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_806701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019439">
        <property type="protein sequence ID" value="GIX67871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M912"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10136" checksum="889BCBB0C79B1A2A" modified="2024-11-27" version="1">MLKTDLIIVLKATVVLICMWFMDNSDILELDFDYISRFQWRSEGTIDSVRTAQALVSREDAPATMRRTSASSYCLEVDVRRLEKIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9H1</accession>
    <name>A0AAV4M9H1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_235460_1</name>
        <name evidence="1" type="ORF">CEXT_494951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002016">
        <property type="protein sequence ID" value="GIX69067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9H1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12125" checksum="B69663D3C399955D" modified="2024-11-27" version="1">MPKNYDQINRARSALNTKLNIRPPAMQMDWRLQAGLKFVVTSKHFQNGNMKLKCTATISRIYTMSNEEMVFGGRQQTSGLHISENMSRMMLLRVFVDGTKEKSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MET9</accession>
    <name>A0AAV4MET9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_304141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019699">
        <property type="protein sequence ID" value="GIX70795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MET9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="15071" checksum="620A80E733C72D81" modified="2024-11-27" version="1">MLFKQASTAYNNIKQYNTLLFVFFFTTRRHLLTRYLTNWTRILHLGGLKIKAEDTLLLSRDNYLKYEFSFSENEYENSAWGSSYSKRKTVSMYLFVNVCSNSLCGCWIGSSNGLRSSRIFQLDLSNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIN3</accession>
    <name>A0AAV4MIN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_205251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019794">
        <property type="protein sequence ID" value="GIX71839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8460" checksum="5820F4C53CD94292" modified="2024-11-27" version="1">MVNREEVLQILLDRRDVTLFAPINDALRKQKARKQDDPKRDESSPMSSFYVYESRWTMPLSSRCILELISTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLR5</accession>
    <name>A0AAV4MLR5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_594841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019883">
        <property type="protein sequence ID" value="GIX72904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="13228" checksum="B0D26E7C22179307" modified="2024-11-27" version="1">MVVRVGYWLKMTEGFRQLSVIRICSVVGRTNSSSTVNLPVFIIINLKFSKRGRFIDYLFIERSVDDVEDIEESNNCANHRKIRWGKEETNSQAEPSERFQLIHIYNNESSLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMA4</accession>
    <name>A0AAV4MMA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_485881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019948">
        <property type="protein sequence ID" value="GIX73397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11814" checksum="1BAF380D511507A4" modified="2024-11-27" version="1">MKQYKKNAPNLNLVRLSFFLPGALIRGRFSDDPISAVTGIDLSKEIARIVAVTRTSRFITAGRLGLQRPLSHRRSDNGEIKQHAPLHRNLAITRVTDPICCVPVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMN9</accession>
    <name>A0AAV4MMN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger protein 431</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ZNF431_0</name>
        <name evidence="11" type="ORF">CEXT_525281</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002437">
        <property type="protein sequence ID" value="GIX73659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF48">
        <property type="entry name" value="ZINC FINGER PROTEIN 771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX73659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="19623" checksum="56DDDAEFF161DC72" modified="2024-11-27" version="1">MSMEREFSPEIHKCLVCDEKFEQKDVLKIHLLNHTFKMENFQLDSSKSFTDANFEDCQNLIFSEEDNLLLDEFNLDIERNKYAVKFKEIHVCSICGKEFRRKDHLQKHFIIHSGKRPFVCLVCGKDFARKDRFKDHCVIHLCNGWSCYFCGKCFLKDAFFENMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MS16</accession>
    <name>A0AAV4MS16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_204671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020089">
        <property type="protein sequence ID" value="GIX74689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MS16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11327" checksum="590C62FF5F82B06C" modified="2024-11-27" version="1">MHHPISIAQIGHQENLLRSLKVQPRDTENFLYSGNHPASTSSSLRVRRICMARLGPFVSLGMEGWRAIHHPPASRGGMVPNIKEERTESNTIEERGMEEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTT8</accession>
    <name>A0AAV4MTT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Small conductance calcium-activated potassium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SK</name>
        <name evidence="11" type="ORF">CEXT_455771</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020202">
        <property type="protein sequence ID" value="GIX75850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016286">
        <property type="term" value="F:small conductance calcium-activated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000022">
        <property type="entry name" value="Small conductance calcium-activated potassium channel, isoform O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004178">
        <property type="entry name" value="CaM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036122">
        <property type="entry name" value="CaM-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015449">
        <property type="entry name" value="K_chnl_Ca-activ_SK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10153">
        <property type="entry name" value="SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02888">
        <property type="entry name" value="CaMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01053">
        <property type="entry name" value="CaMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81327">
        <property type="entry name" value="Small-conductance potassium channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calmodulin-binding" evidence="10">
        <location>
            <begin position="108"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX75850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="256" mass="28893" checksum="467E5808BE0E0A18" modified="2024-11-27" version="1">MVSRILTKPHHTKKLDKHVQPHNSRLTQELLKYHDEEHANLLNTMWLTAITFLSVGYGDIVPNTYCGRGISVSTGLMGAGCTALVVAVIARKLELSRAEKHVHNFMMDTQLTKRLRNAAANVLRETWLIYKHTKLDKRVNQSKVRAHQRKFLLAIYSLRKVKMDQRKLMDNANTITDMAKTQNSVFEMVSEMNQRHEVLEERVLSLEDRLTVIQEQLEALPDVLTKALSALPALNSTETQPQSGGTAATTIGTTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZ75</accession>
    <name>A0AAV4MZ75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Degenerin mec-10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mec-10_3</name>
        <name evidence="14" type="ORF">CEXT_633121</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020296">
        <property type="protein sequence ID" value="GIX77028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZ75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX77028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="24961" checksum="4B3D60D961835423" modified="2024-11-27" version="1">MSNIMEVNDRIQNSSVYAISQIGYSKTSCSKITWISILTCALIGCCYQIYGFIDQYFKYPVIVDLLMEQPETITFPAVTICNLNRMKGKQHKDTDSYVEFLDKYFALDHEKHYRFGHKVDDLVMNCSFNGKSCNSAFFLRSWNFRYGNCYTINGSKQMLTSAASSKGLELILHVKPKDYVSVSHTIGMRIVIHNPWTMLTLKEMVSIYSQDAKPIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZW4</accession>
    <name>A0AAV4MZW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_559061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002696">
        <property type="protein sequence ID" value="GIX76827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11567" checksum="3615581782964E88" modified="2024-11-27" version="1">MCIIHPGIRINNVSICGMVSNIVFINGILMYSLSINGMLINSISINGVSICYIPIHDLSISGLLIKGVSICCIRSNDFTVCGMLINGVVIYGIHINSVSIDSILINNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NF08</accession>
    <name>A0AAV4NF08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_269861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003328">
        <property type="protein sequence ID" value="GIX83392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NF08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="18931" checksum="89FF92C4F4148E8C" modified="2024-11-27" version="1">MTSKRTSKSGKVVKEVSLTTIAVQEGNHTSKTNFEKRQSSERSITNHYSSAGREPCSENVKDVKTTVEAPKSGKVVKEVLPTTIAVQEGKLCSENVKDVKTSDEASKSGKVLNDVSPTTIAVQVGEPCSENVKDVKTSVEASKSGKVVKEVSLTTEVVKDIKTNFEKRQSSERSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIC1</accession>
    <name>A0AAV4NIC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ornithine decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">spe1</name>
        <name evidence="6" type="ORF">CEXT_339611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003424">
        <property type="protein sequence ID" value="GIX84403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000008">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX84403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="292" mass="32337" checksum="739401ED30C8D734" modified="2024-11-27" version="1" fragment="single">HEINAVINLGVAPNLIVYSNCYKAASHLRHAVQLGVDLMAFDNREELVKIKLLYPCARLLLRIKIVASSAFVPMSCKFGCDLDIARDLLYFARSLDLTVVGVSFHIGSLTQDPKDFEGAIQLSRSVFDAAKSMDMKLTVLDIGGGFPGCKGSADLFKQMAVTVNRAIDEYFPPDGHYAIIAEPGRYIVTSAFTLCANIIGKREKQTNEGLEVMYIINEGIYGLFAHNVFHGYKPKPVLKRNGQVRSSCPVARHGCLLDCVLINIQRFRENGSQIYHAPETIGHCLKIECDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKS5</accession>
    <name>A0AAV4NKS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003511">
        <property type="protein sequence ID" value="GIX85390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10683" checksum="00C0EEA0B362358C" modified="2024-11-27" version="1">MGEGGGFPQNRLSPRLETTSEWRAPLQAVIAQAAALNANGRKLSDRRCKVCLNCISGFPYLPGVSGFGFLEPVRFRPEIFSIPFQREICKEKLTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM47</accession>
    <name>A0AAV4NM47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021105">
        <property type="protein sequence ID" value="GIX85900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20495" checksum="1327D8C90F1A4978" modified="2024-11-27" version="1">MFIDNLQCLLSLQRHTWYVYLLSQTSVIVSVHLITLKRPFSAILHCLFLKRLTLGKLDTRPSNPLFQNMCLYCLISRLERIGRQSLYQHTWYVHPLPSTSLIVPLHLITLRKRGNLSDGPATLSACALRDWSLWASRTRSAAFVMSPSKCSSGGFSFVPTFFSEKNVFVLGEGSFRVVSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNE4</accession>
    <name>A0AAV4NNE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003513">
        <property type="protein sequence ID" value="GIX85446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11567" checksum="C08FD6AE14D1F5B9" modified="2024-11-27" version="1">MHLLLLLSSSTENSPNLMCSSSPMGTQSSVSKIPNQISFSCETIVLSIRQNLGSHPPCCTRWGPSWHNQLCCENRYSQPGRPLVQYINCSTSAQEHYILLNVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQT0</accession>
    <name>A0AAV4NQT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_188831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021115">
        <property type="protein sequence ID" value="GIX86135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9498" checksum="3221EE3445C2243D" modified="2024-11-27" version="1">MATSPQSPFTQRRQKINTEAVYNNRSEYGKEFDPSYLVDLRIPRSEPFFPPKRSFPFTVGERNSLEGDGIGMFVIVFSEEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NT53</accession>
    <name>A0AAV4NT53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_530261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021285">
        <property type="protein sequence ID" value="GIX88027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NT53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9229" checksum="0968C9C00FCB7096" modified="2024-11-27" version="1">MCYGDESSREMMTEGMDFCSANRPFQDPLTPLSSDQNGQEQSPDYTCCIIHQHEKVIENYQMELSYHLMYLRHTTVQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYH9</accession>
    <name>A0AAV4NYH9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxin-19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PEX19</name>
        <name evidence="5" type="ORF">CEXT_73721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxin-19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003906">
        <property type="protein sequence ID" value="GIX90007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033328">
        <property type="term" value="F:peroxisome membrane targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="47"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX90007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="296" mass="33499" checksum="6F367A35D1486FF2" modified="2024-11-27" version="1">MIRILRPVLFSGSKMEDKEKTKDSAATVSGDDLSDLLDSCLDDFNKPLPKTVITNTQPTEGSSSQQPSAESDKPLDSSAWGEEFKEYSEVIENIIGAEGPELNEFKKLMDNYMTQEGPQINDEEFAKSFAKTIQEMTQQTHNIPETSPDDVANLLGSLGLGNNPDVESMPELMPIMQSVMQRLMSKDLLYPSLKEIVEKYPGWLNEKKSSFKTEEYDNYQKQYEHMKEICEEFEKDVDQSEAAKKEQFETVLKMMQKVQNYGNPPKELISSINPSIPLDEEGNLQVPGMPEQCIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P700</accession>
    <name>A0AAV4P700_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_37051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021685">
        <property type="protein sequence ID" value="GIX92370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P700"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9948" checksum="9D8F07BA11B64D1C" modified="2024-11-27" version="1">MWKTEASEQLHSNTFLSNCLCHLADDRADQGFVAKRVGGRVALSKRVCEEVAHFITFPRFFYSVQCESRALWKSKDRLLLLPDLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBS5</accession>
    <name>A0AAV4PBS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase-like protein 7B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">METTL7B_0</name>
        <name evidence="1" type="ORF">CEXT_319081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004278">
        <property type="protein sequence ID" value="GIX93621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="234" mass="26756" checksum="D18D1D00F7C8598E" modified="2024-11-27" version="1">MSAVSCLLPLVVLLKVNKTFRNKFSVLYMELFGFVVRQMEPIRKRAFEILQEHLPNRKLSTPLEILEIGVGGGANLEYYPENSNLTALDKNDTFSNYFNDHKKKFSHVTYKKMVSSMAEKHGRNRRFFDGRGRGTYVLCSVQDVKAVIKESEACTEASKFLFVEHVAFPDSHLGSKVQNFAAPLWRLFCDGCNINRKPSEEIRKGGFSNVECENQFPSNAWLFLRPQFIGIATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PC94</accession>
    <name>A0AAV4PC94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major ampullate spidroin 1F variant 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MaSp1F2</name>
        <name evidence="5" type="ORF">CEXT_900101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021716">
        <property type="protein sequence ID" value="GIX92757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1350">
        <property type="entry name" value="Spidroin domain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021001">
        <property type="entry name" value="Spidroin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038542">
        <property type="entry name" value="Spidroin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031913">
        <property type="entry name" value="Spidroin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038243">
        <property type="entry name" value="Spidroin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11260">
        <property type="entry name" value="Spidroin_MaSp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16763">
        <property type="entry name" value="Spidroin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043954974" evidence="2">
        <location>
            <begin position="25"/>
            <end position="3036"/>
        </location>
    </feature>
    <feature type="domain" description="Spidroin N-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Spidroin C-terminal" evidence="3">
        <location>
            <begin position="2936"/>
            <end position="3019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX92757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="3036" mass="237020" checksum="E3F50A813296E529" modified="2024-11-27" version="1">MTWTSRLALSLLVAICTQSMFALGQDNTPWSSTGTAESFMSSFMSAAGNSGAFTDDQLDDMNTITDTIRSAMDKMARSNKSSKSKLQALNMAFSSAMAEIAVDEGGQSVGYKTNAIADALSQAFLQTTGVVNGAFINEIRSLISMFAQNSVNAIGSGGSSASVSVAASAGGGYGGQGSYGPGPQGPSGPGPQGSGASSASAVSAASGPGRYAPGPQGPSGPQGPGQSSYQYSVSISTQGGSQGGYGGQQAGAGQGGYGGGLGGQGAGAAAAAAAAGGAGGLGGQGGQRGGQGAGGAGQGGYGSGIRGQGAGSAAAAAAVGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAATAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAASAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAASAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAATAGGAGGRGGIGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAATAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAVGGAGGRGGLGGQRGGLGAGGAGQGGYGSGLGGLGGGSTAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAATAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGIGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAASAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSVAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAASAASAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGRGGLGGQGGGLGAGGAGQGGYGSGLGGLGGGSVAAAAAAGGAGGLGGQGGGQGAGQGGYGSGLGGQGAGSAAAAAAAGGAGGLGGQGGYGGQMGYGGGYGGQQVAASAATASAAASRLSSPDASSRVSSAVSSLVSSGATNPAALSNTIGSVVSQIGASNPGLSGCDILVQALLEVVSALIQILASSSIGQVNYGATAQSTGIVSQSISQALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PEX6</accession>
    <name>A0AAV4PEX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_292891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004281">
        <property type="protein sequence ID" value="GIX93657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PEX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12749" checksum="69B2D2556CE72BD0" modified="2024-11-27" version="1">MIRNRAKLAWKASTDKKESAVVTQEGRLHTYFGHLFFGPIKVSFYLRIFPILEKEWICRLFFPQKNLLSKILFYKGRSSFNERGCYRLYLRRKCPRRDFPIIVANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PR48</accession>
    <name>A0AAV4PR48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_690201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004937">
        <property type="protein sequence ID" value="GIX98631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PR48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12492" checksum="CA12B8113CA5A700" modified="2024-11-27" version="1">MDEFINVPHGRSRFQTRAGARVNLSVFCRPAVAPPHSAASRQRAIWQETRSVPKNTSSVVTKCHVFYSRQGLLKKSTVIQELNSGSTIFQNIKHLCSAPEVEVIPPVDTYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0E1</accession>
    <name>A0AAV4Q0E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_706791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005235">
        <property type="protein sequence ID" value="GIY00873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15324" checksum="9C00F7F182CAE8C9" modified="2024-11-27" version="1">MIQKNHRSICPDVFLLNTLSYNRRANKGPYKLRPRAPEYRCRLSIRTTFQVLLEHAVAATMEQSGVNCSRPHGDRPETDPRSSDRQDIRSKTSGQERKKKLPLGGAVSTVARRGLFHPSFVACCATDCGVTGKRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q767</accession>
    <name>A0AAV4Q767_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_510651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005659">
        <property type="protein sequence ID" value="GIY04052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q767"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10816" checksum="1AB1AEE35098A8CA" modified="2024-11-27" version="1">MRVEGIVVAPAPALFFVVGGPHARGKGVRRASITPFRYYWGVGGCLILTGDVKDQIDLMDSELGFQNCRRLEACENDVEKRKYVKMSIKRCQNVLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8T6</accession>
    <name>A0AAV4Q8T6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein heavy chain 7, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DNAH7</name>
        <name evidence="2" type="ORF">CEXT_350771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005890">
        <property type="protein sequence ID" value="GIY05880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8T6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF70">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 2, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15292" checksum="39080910D58975FD" modified="2024-11-27" version="1">MPVLETYGAQPPIELLRQWLDHWTWYDMKEVVPIKLVDTQLICAMDPPGNLICVNFQTSIYNQDGYPKNKQDSYTILSLLPQRHGAKTQRVLSTLGKASCLSPPRDNSRRTRRRREAPGRAAETLEHGCLASGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QF96</accession>
    <name>A0AAV4QF96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_390221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006036">
        <property type="protein sequence ID" value="GIY07026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QF96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9004" checksum="6F69E095F988AF7E" modified="2024-11-27" version="1">MNVKLKDSSQVRRINSFMSFHKEREKTLFKGDHIGSYCKAGYAIDFVAQFSKGIHKAHKETCLNAEYIESSNQGICLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QP51</accession>
    <name>A0AAV4QP51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_586691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006651">
        <property type="protein sequence ID" value="GIY11473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QP51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9443" checksum="F12E8533AE01D8CA" modified="2024-11-27" version="1">MKDDEFGKIKLTSLHSPIGFKDTGLAQPCISQVLKNTQVDKTCLSKSVKLIMKDDEFGKIKLTSLHSPIDSKTQDLHSHAFHKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1V3</accession>
    <name>A0AAV4R1V3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_418111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007113">
        <property type="protein sequence ID" value="GIY14604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1V3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10426" checksum="553033AF026F89AB" modified="2024-11-27" version="1">MGVFSPFYAYPIFLNILRVSICWTKIIFPATVAIAFGPESMPKTISHLFLAIYSEGGKLSSWLFFSISGVMDGYKDRQMFSPIREYEQKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3A3</accession>
    <name>A0AAV4R3A3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_809511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007321">
        <property type="protein sequence ID" value="GIY16024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1147"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1308"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1557"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1154"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1322"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1562"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1586" mass="181363" checksum="C36BE07C4E8ADCD0" modified="2024-11-27" version="1" fragment="single">AHSARSSFGREAHSAESSFGRSSFGGAHSAESSFGRELIRQRAHSAESSQLRQRSSFGKKLIRQRAHSAEAHSAESSFGEKAHSAEEAHSAEKLIRQRAHSAEKLIRQRNSFGRESSFGRELIRQKLIRQRAHSAESSFGRELIRQKLIRQRAHSAESSFGRKLIRQKAHSAESSFGRELIRQRAHSAESSFGRELIRQKLIRQRSSFGREAHSAESSFGRKLIRQRAHSAESSFGRSSFGRELIRQKAHSAESSFGRESSFGEAHSAESSFGRELIRQRSSFGRELIRQRSSFGRELIRQKLIRQRSSFGRSSFGRESSFGRKLIRQKAHSAEKLIRQKLIRQRAHSAESSFGRSSFGREAHSAEAHSAESSFGRELIRQKLIRQRAHSAEAHSAEAHSAEAHSAEKLIRQRAHSAESSFGRSSFGRELIRQRELIRQKLIRQKLIRQRAHSAESSFGRELIRQRSSFGRELIRQKAHSAEAHSAESSFGRGSSFGRELIRQRAHSAESSFGRELIRQELIRQRAHSAESSFGRSSFGRELIRQRELIRQRAHSAEAHSAEAHSAEKLIRQRAHSAESSFGRKLIRQRSSFGRELIRQRAHSAEAHSAEAHSAESSLIRQKLIRQRAHSAESSFGRKLIRQKLIRQKLIRQRAHSAESSFGREAHSAEELIRQKLIRQRAHSAESSFGRELIRQRAHSAESSFGRSSFGRSSFGREAHSAEAHSAEAHSAESSFGRSSFGRELIRQKLIRQRSSFGRELIRQRAHSAESSFGRELIRQRSSFGRELIRQRSSFGRSSFGRELIRQRELIRQRAHSAESSFGRELIRQRAHSAEAHSAEAHSAEAHSAESSFGRSSFGRELIRQKAHSAESSFGRELIRQREAHSAEAHSAEKLIRQKLIRQRAHSAEKLIRQREAHSAEKLIRQKLIRQRAHSAESSFGREAHSAESSFGREAHSAEKLIRQRAHSAEAHSAESSFGRELIRQRKLIRQRAHSAEKAHSAESSFGRELIRQRSSFGRRSSFGRSSFGRLIRKLIRQRAHSAEKLIRQKAHSAESSFGRKLIRQRELIRQRKLIRQKLIRQRAHSAESSFGRELIRQRSSFGRELIRQKKLIRQRAHSAEAHSAESSFGRELIRQRAHSAEKLIRQSSFGAHSGEAHSAESSFGREAHSAEKLIRQKLIRQKLIRQRAHSAEEAHSEKLIRQRAHSAEKLIRQKLIRQRELIRQRSSFGRELIRQKLIRQKLIRQRSSFGRELIRQKLIRQLIRQKLIRQRSSFGRELIRQRAHSAESSFGRELIRQRAHSAEKLIRQRAHSAESSFGRESSFGREAHSAEAHSAESSFGRELIRQKLIRQKLIRQKSSFGRKLIRQRAHSAEAHSAESSFGRKSSFGRELIRQRAHSERSSFGRELIRQRSSFGRELIRQRSSFGREAHSAESSFGRELSSFGKLIKKLIRQRSSFGREAHSAEAHSAEKLIRQKLIRQRAHSAESSFGRSSFGRSSFGRSSFGRLSSFGRSSFGREAHSAESSFGRELIRQRAHSAEAHSAEKLIRQKLIRQKLIRQRAHSAEAHSAEKAHSAESSFGRKLRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RB80</accession>
    <name>A0AAV4RB80_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Antifreeze protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_802421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007592">
        <property type="protein sequence ID" value="GIY18256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RB80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="14698" checksum="09007F8D5C469FF5" modified="2024-11-27" version="1">MNLPSFNTEPLKFSLPSSPLLLVFAHGASIKPDVQGRRGLGLGLGLGIGLGQGVAMDKVAMVMVVMAMKDMDMEAIDMEATIKAVMTEEPMIGELTIKEIMVKAITDTEDTAMAGMAMVDMVANKQFSSGKISSSACIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFI4</accession>
    <name>A0AAV4RFI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from transposon BS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RTase_323</name>
        <name evidence="2" type="ORF">CEXT_495351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007885">
        <property type="protein sequence ID" value="GIY20445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052560">
        <property type="entry name" value="RdDP_mobile_element"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688">
        <property type="entry name" value="ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="29250" checksum="7D280693AF7DD56B" modified="2024-11-27" version="1">MIHRTYKKLLAKREHLLQNNNLNDNTDARIELNKINAEIKLYLGSCATKRLLHIFNLWKLGRLPRQWKTAIVVPIRKPNKDASCMGSYRPIALTCMTCKLMERIILRRITFHLMNRNMLPQEQYGFRKGHSTIDQILLSNGIPTGFSFDPTLFSLYLTGIERVVSPCQIGIFADDIIVWDHNSDLTKLENTLNDMLEKIQHFADEHKLTFNTTKSLSCLFTTNRHLFNYQPKIFLNGQLLESTKTPTYLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKJ2</accession>
    <name>A0AAV4RKJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_665161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007940">
        <property type="protein sequence ID" value="GIY20846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044022595" evidence="2">
        <location>
            <begin position="27"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY20846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16257" checksum="EC38A517A3774B35" modified="2024-11-27" version="1">MGRIKPMNYCCLGFWISACCLGLASTGNSLTKDFNYTVLEENTLSDIIEVVTLNYSEISITDKTDGTTRKEDTTSHPDEIRNNTRKRTRVAVLSEKDSGHAIMPLAAGGLALLGGLLLVSVVVGLFMYCNRNTGYVYEPALTSDVSTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMC9</accession>
    <name>A0AAV4RMC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_631471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008022">
        <property type="protein sequence ID" value="GIY21461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18657" checksum="29D2DA70FC965CAE" modified="2024-11-27" version="1">MVHLEVVQILSLRCYTTKREKISTAIPLLIAIIGSLIVHLEMVRVLSLRCYTTKRKNIHCYWCCNYWLAYSSFGSGSDRGKKEKNIHCYTIAYCNYWLVYGSFGSDSGIVAKVLYHKRGKNIHCYTIAYYNYWLHLVVMVNLEVVQVLLLRCCQVLSMRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY61</accession>
    <name>A0AAV4RY61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nipped-B-like protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nipbla</name>
        <name evidence="1" type="ORF">CEXT_130941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008722">
        <property type="protein sequence ID" value="GIY26685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090694">
        <property type="term" value="C:Scc2-Scc4 cohesin loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061775">
        <property type="term" value="F:cohesin loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140588">
        <property type="term" value="P:chromatin looping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="405" mass="46589" checksum="F65E8A5CD6D47197" modified="2024-11-27" version="1">MYAESPGQKMKIAEILLKKIPPTTPTASLSKVKKLKSRKLKKNLPQSHYPIEDLMDTNTYQHFSRIVDIIFDSMEDIDFSVVIDEDTECAAEVLVPLNQLQDLSNEAAKLKRLHATNQFPPERLVRLLAILERNIVDGAKLLPMQGLEEQDEEETRLWLELTMERVMRSADASLTALYIMTSPKMPEKVFLEDVIERITLFVKFQLHNTVFPVFDPAYRLDPKSKDGYAGNIKQKRAHAHKVKEKSTLQLYNKLHESVSLLAELLELQTLPDTIILQVSTLGVSPFFVEGISELQLNALRLVTTVFSRYDKHRQLILEDILASIARLPTSKRSLRNYRLNSEENIQMLTALVLQLIHSVVKLPEPDVDTKKENVLLMKNIPKILKLKKKFILIKMFFSLHLMKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYZ1</accession>
    <name>A0AAV4RYZ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZMYND11 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_671911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008746">
        <property type="protein sequence ID" value="GIY26914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057054">
        <property type="entry name" value="ZMYND11_CC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23461">
        <property type="entry name" value="ZMYND11_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZMYND11 coiled-coil" evidence="2">
        <location>
            <begin position="149"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY26914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21289" checksum="BCE515E8CBA6D207" modified="2024-11-27" version="1">MKGNHQRRLRNSRISEDIQLIHEVGRIKRKYTRRLRDAVVSEDNNDQNLVSSSSQETAVSYSSVAIQTENETCSKQERKRSVGRPKGSFRRHHRVVEKDESPPSVNMDTSTNDKVEKTHDCVNSSINNVENTPNCVDTSTNNNKAEKTCDCSAKYEKALQDLRNSLEEEHKKDKSKALQELSEKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7M6</accession>
    <name>A0AAV4S7M6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynein heavy chain 5, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dnah5</name>
        <name evidence="4" type="ORF">CEXT_131211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008965">
        <property type="protein sequence ID" value="GIY28601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7M6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46961">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46961:SF19">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 5, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="3">
        <location>
            <begin position="23"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="3">
        <location>
            <begin position="104"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY28601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="318" mass="35968" checksum="85675EBEA255F4DF" modified="2024-11-27" version="1" fragment="single">WTPPEVTGEEEAEVEMPKIYEPISRIIRSPGGHALLVGVGGSGKQSLTKLAAFIAHYNTQQISLTRNYSATNFLEDLKILYRTTGIQDKGTTFIFTDQALKDECGRKLRARSLKFPGIVSGCTVDWFQPWPKEALTSVSRHFLKDFDMQCDQVIKQEVILFHGRHAQLCCRAMQRILPKVPPPRPRDPKSFLSFLGGYRRLYEEKHREIGNTCRRMENGISKLEEASFLVEGMKETLAVMEEELEVASKTAEQVLAEVSVRADAAEVVRDSVERAKNAAQEIVKEIQADKAIAEENWRRRDPHSKTPKQLSTPSSPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9P0</accession>
    <name>A0AAV4S9P0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_257511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009024">
        <property type="protein sequence ID" value="GIY29120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9P0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="11081" checksum="5B95E63B259EE3FE" modified="2024-11-27" version="1">MDVNLNWMFADDTYPQIWYNDLNFAQEQSSKKPGAKQTIQMRKDDGFSVKNKTLYDPQQNSFNIYGLFNINVRYLCLLSFCWFNRVQFKFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGP8</accession>
    <name>A0AAV4SGP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">DDZ39_07815</name>
        <name evidence="1" type="ORF">CEXT_457231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009373">
        <property type="protein sequence ID" value="GIY31397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21794" checksum="67D508E49BD495F8" modified="2024-11-27" version="1">MDKTNFCVFSTDRKHRGTFNSNTKINDSPIKKIDLTFIPTYLITMDPEFPFTRHIVHIANKALRKLSILKNLRGTTWGSRPKTVKNAFCSIIRPLLEYAAPIWNPNSQPSKMDSVQHRASKIIIGAVSSTDNNKAEQEWGLPLLENRRNLATIKFTNRLRSKNMDHISTRVFNEWKRLNKTQKILNSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIZ6</accession>
    <name>A0AAV4SIZ6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009514">
        <property type="protein sequence ID" value="GIY32465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="22303" checksum="77AC7615D3171A83" modified="2024-11-27" version="1">MKINNKRIKLFEPIRVSVFLQNFSWMSGRRPTQLFHTRFPCRLGDMEKGYEIAICQSEGNVPTPTSLQVRQVKRQDSGIYQCFVNRKSFLRRPAPDLSLVVEVYQKREHIFESADQRAMFPTPTSLQVRQVKRQDSGLYQCLVNRKSFVRRLAPDMSLVEQVGLVSIRRGFIAFEKENDEYDLPRLGSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKL0</accession>
    <name>A0AAV4SKL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009628">
        <property type="protein sequence ID" value="GIY33371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9310" checksum="5A4342B9BB21725F" modified="2024-11-27" version="1">MSDGDALCLDCVRREERDDAPHLATSFRPVGAKRIFFGSGTSPVPRAIPAGIGRGTLVMDSYGLVRGCREHVSRIPDERTPCRGVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ST86</accession>
    <name>A0AAV4ST86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_46401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010040">
        <property type="protein sequence ID" value="GIY36396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ST86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="316" mass="36812" checksum="068587E457F23B61" modified="2024-11-27" version="1">MRSGQKTVLQESWIDDRVDRGANVSITNCATLFQYFCTPPPPHHPQSGRMVFQQYFSPHLQFQQYFFLTYSTFPHLQFLQYFSSPTTVPTVLFSSPTVSTVFFLAYSSYSTFPYLQFLQYFSLTHSSYSIFPSPTVPTVLFLTYSTFPHLQFLQYFSSPTVPTVLFLYSSYSTFFLAYSSYSTFFPHLQRSYSIFPLPTVPTVLFPHLQFLQHFFPHLQFQQYFSSPTVPTVLFPRLQFLPVVFPLTYRSYSIFPLPYSSYSTFPLTYSSYSTFPHLQFLQYFSSPTVPTVLFSPTVPTVQYFSSPTSSPQFQKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZQ8</accession>
    <name>A0AAV4SZQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_163291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010440">
        <property type="protein sequence ID" value="GIY39280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12126" checksum="C53EAF5558D47B54" modified="2024-11-27" version="1">MLIFNTNCLIFGNKLLVGFWGKDLLNQALDQWTIVIELQMRGKFRLRKNISWTYYCTSEDPPSSWCPRDPQVVTRLSDSKRCEILHFFKRSKNEEVGPEWPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1V9</accession>
    <name>A0AAV4T1V9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_134921_1</name>
        <name evidence="2" type="ORF">CEXT_468461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010647">
        <property type="protein sequence ID" value="GIY40688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1V9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052579">
        <property type="entry name" value="Zinc_finger_SWIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048324">
        <property type="entry name" value="ZSWIM1-3_RNaseH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569:SF4">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21056">
        <property type="entry name" value="ZSWIM1-3_RNaseH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZSWIM1/3 RNaseH-like" evidence="1">
        <location>
            <begin position="30"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="491" mass="57289" checksum="FC6BD2082936ACAE" modified="2024-11-27" version="1">MFSKTKLMTKSSGCASDDVQSDFKSLFAYLEEKFNAISEYLLDANGFLSCIYFQDSFMKDFFNFYPDRLCIDVSFKSFETDIFMYLFSAEDSNGKNDVISLGFTVSDNAESFLWLLNTFKKNNPNWRRIKIISLDSEIKQRDIIRNVFQGPYIIITLYHALKSFKKGLEVINEQNNLPIDQIQTSVELFKNLYIAHRPAEYELYYQQFMLMQSPIVSFFEDIWLPIQNQWRTGLDFNHENVFSSLNSHLEYLDNTIKFNGMECEIPSTKTDCHESNSLKSSSTVILSEPVNSISHFSISSDNLLNDQSVFDLNFKPSTWNFKSRILDGKYINYAYLCRIICDTKESCLDWLKQMELIPSSVMCPSCNCEMVIKYVPRLSDGAVWVCSNMMVSKRNCSRRCSVRQGSWFELTNMTFEQILTFSTYISWNKLNRRVCEEVLSEEGKISNNSKNDSSEVLEMWLKSCGDEDSFLKFLQDANMMHRKDSLKRIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T293</accession>
    <name>A0AAV4T293_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_478291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010454">
        <property type="protein sequence ID" value="GIY39354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T293"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9106" checksum="152B41CEA62B88DE" modified="2024-11-27" version="1">MVRNTALEKGIELADINNRNENYELEEVSYQILEDVLGRRDPINDSSAKSFKHEFENLNPELRRLQVRGQNELLFATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3F6</accession>
    <name>A0AAV4T3F6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_438381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010296">
        <property type="protein sequence ID" value="GIY38388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3F6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11348" checksum="6007940B3D15ED28" modified="2024-11-27" version="1">MTLCVFHVWETYKYNFTLVSDKYPKHAISSPAYPLTTLLLAISGILTFHPSCRRACGLLEKIAKFPIDFKVEILSESIASSVRNSSFVSVDIDLRSNCFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7I9</accession>
    <name>A0AAV4T7I9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_675061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010529">
        <property type="protein sequence ID" value="GIY39903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="88"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15758" checksum="3371702811AD05BD" modified="2024-11-27" version="1">MDKSCDTEFSSDQLMEGTTFVLSLSKIKIIESDTYPLYDLLSLRCVYTFPPTRDISEEIERLDYGYAGSQDQNEFVKKDFLYEDPLLSDMKLKTETKTFDAHAAVLSARSEVFKIMFNIEMTEKLNRNVYISDVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T906</accession>
    <name>A0AAV4T906_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metalloendopeptidase</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_87251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3 4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01010739">
        <property type="protein sequence ID" value="GIY41694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T906"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF883">
        <property type="entry name" value="ZINC METALLOPROTEINASE NAS-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="5">
        <location>
            <begin position="168"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY41694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="372" mass="42215" checksum="1B71CC41209B667C" modified="2024-11-27" version="1">MLREYIFVIYIVSWESPSPGTYGALQVEVTEHVIVICDGDFSVTGSTAAVLGGVLRCRRWQNKLINLTYFQRIINISVLFLLPDLVWDDAVLENPDLFEGDILGVDPKKSPWLHNGKGLASCIFFPVLINAGRKTHGTSGNGQRGDIPRTACFFCDRNIFCYYFQDRNAIVGEEKLWPAGVVPYELDNGLSSTVSLNVLQRAMWKYGNKTCIRFVPRTKEPAYLHIFPGQGCYSYVGRKKAEGAQPLSLGKGCNHMGTMLHELGHAVGFYHEHSRSDRDDWITIHWENIKEGTESQFFKLKPERNQLLTPFDYNSIMLYGSYTFSKEKQKFITMVAKDGRLLNSTRQKTNLAKNDAVRIKKLYKCKGKQVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEQ4</accession>
    <name>A0AAV4TEQ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_286871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011044">
        <property type="protein sequence ID" value="GIY43871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8934" checksum="7C348D52445B28E5" modified="2024-11-27" version="1">MLPMELPGLHEIALRKRDPNDDDRLHPLTSLHFTINNENTTSNSNSPTYINASGFIETFYFISYYNFSSTTATAESSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS21</accession>
    <name>A0AAV4TS21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">jockeypol_106</name>
        <name evidence="2" type="ORF">CEXT_644941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011732">
        <property type="protein sequence ID" value="GIY48599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF4">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="100"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="260" mass="28852" checksum="0A8B817825F47F7E" modified="2024-11-27" version="1">MGMIMDDHTYTREKEDAMEVTAEGSLALFRTSYRRSLPRAVADLFNHPLRCGTAILIKNNISHHEVPTPSLNSIKTTIISVHFANIPPPPPSLLLFMLPAASDLLTDLTTLLSINNSSILSGDFNSPHIRWGSHTNSYTVINLLNFSVRTGFEIIAPSTPTRYGLNSSSVIDPTILNNFHCTYDITSISELSSYHNPVLLNFNVNYITLNIPLKFPPTGKPLPNSFLQITPLFPSNIDNSNDLETAVDNLTTNHRLQSCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS77</accession>
    <name>A0AAV4TS77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PRKG1_interact domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_225275_2</name>
        <name evidence="5" type="ORF">CEXT_795072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011793">
        <property type="protein sequence ID" value="GIY49060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004857">
        <property type="term" value="F:enzyme inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019208">
        <property type="term" value="F:phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051226">
        <property type="entry name" value="PP1_Regulatory_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031775">
        <property type="entry name" value="PRKG1_interact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24179:SF21">
        <property type="entry name" value="MYOSIN BINDING SUBUNIT, ISOFORM O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24179">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15898">
        <property type="entry name" value="PRKG1_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="cGMP-dependent protein kinase interacting" evidence="4">
        <location>
            <begin position="172"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY49060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="30024" checksum="B2026B21701CB2F8" modified="2024-11-27" version="1">MSYGNYGRYGSGYSSYSGSNRRLGSSSYLPSSYTPRRTIGGPYGLTPSYSSSYLSPNSSPRSSISSGSTREVRPSYSSYKTLTGDSRRSDYSPDRTGYRLTSSKSSSSLRSDDGSDLSSLYEGPTTERTRQRYGSSTSIPDTASEASYKSDASSRYGSKASLRHIPMLILLKQLYEELKKENEKLKDTLRKTEDELEKTKKQLQKLSQSSTIKNSVSEAEKKERRSLERKISEMEEEIKQNEKLRADNERLREENAALIRVISKISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5P8</accession>
    <name>A0AAV4U5P8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_77831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012318">
        <property type="protein sequence ID" value="GIY53053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5P8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9948" checksum="BFABB27D2D50830A" modified="2024-11-27" version="1">MFKAGRGLVNPDLMDVWRGCLPVDFRGKTLLHLHIRKLSVGCWNIDAIPLVSRKESPQAATIIYIANDCEHASSCDRNIHGTAGTRTMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U607</accession>
    <name>A0AAV4U607_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">NAAT1</name>
        <name evidence="17" type="ORF">CEXT_139611</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012332">
        <property type="protein sequence ID" value="GIY53223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U607"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY53223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="492" mass="55743" checksum="B66C9044D6D8F459" modified="2024-11-27" version="1">MTIGWEMFGNGMWLYHNGGGAFFLIPYLLVLFIIGKPLYYLELILGQFSSQGPIKVWRIVPAFKGKLCMYWICSVTFFGVHPYLLQLLDGSVPLLLRLHATPACRGRNAITPTELLMKMGQPSMVNLHPNISGYVILHLHFPIRRTLHIVHHSLLEEGAWQGIKYFFLPNLEKLKNITRCIDYLCSGYRYKSVGGSVTFAMLGSLAYKYSKDIHDVISHEGLGLAFVVYPDSLAAISYVPQLWAVLFFFMLYILGIGSSMAQIETLLTVIKDKYPKLRKCIWLPSLIACVIFFALGLPLTTNYGQQILQLLNNSGVTAVVLLYAVLEVVGVAWIYGLRNFCNDVEFMLNKRPGIFFKFTWSCLIPVSMVFIFRVRHSGCRGAHKDPSMPQWAYHVGWFLGVLALIQIPLWFFIEVYKSPHTGIVKPNYSSKMSDKENDLPPRMTWSKSVECLLMCVSMTIGLGNVWKFPNVTYNNGGGEEILDILFIPTATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6S3</accession>
    <name>A0AAV4U6S3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_628661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012367">
        <property type="protein sequence ID" value="GIY53452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6S3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10719" checksum="79B738EC8B223F0E" modified="2024-11-27" version="1">MATVKVLLMSSSLANIAHKWHAFPLRDKEGALCGIRSPHASKFAVVFSLVTRLSLTVERERTGWNRFKTMSMAIGIVRSHTTEPLNHYKAVRLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7T5</accession>
    <name>A0AAV4U7T5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_308111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012403">
        <property type="protein sequence ID" value="GIY53776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7T5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16453" checksum="A981B8C9E00B7B74" modified="2024-11-27" version="1">MEMKTGKGKIFGIAKARPVFVFRNLFILLMIGFMSKFSCINVTEMFGALQTVRQGLLLRLLGPPCGCNDGLKVMMWPRDPPGLAVVSWSRPPGNHAPLLTTKWDHVHGPASGGIRYRFSQGCRSQGALVTCLQKIKNYKCHFSKIEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCZ3</accession>
    <name>A0AAV4UCZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_702991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012662">
        <property type="protein sequence ID" value="GIY55659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12575" checksum="F1764D459C2EF470" modified="2024-11-27" version="1">MRIELKMKRRMLLREDRCYLIITILRFPLITDEKDQICTPQSVATLLKPLALRPIIYFAQLLGVNAAYGRKFVIASDDFLVPQQFKSEHCLPRPPDFCVSNLAPPKAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UD14</accession>
    <name>A0AAV4UD14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_303051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012669">
        <property type="protein sequence ID" value="GIY55752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UD14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11929" checksum="85B0897C20492AD8" modified="2024-11-27" version="1">MVTTVNTKCRNVLLLHIEIEISQPAENKQKRNCAFNLLGSDCDYTPMAGMSKDHSFRMSLDGPGKKRRKRSCLINMPGLNCDFNQMVGTGKDLGVWSSLAAPGKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDS0</accession>
    <name>A0AAV4UDS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zwei Ig domain protein zig-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">zig-3</name>
        <name evidence="8" type="ORF">CEXT_367291</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012705">
        <property type="protein sequence ID" value="GIY55968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001749">
        <property type="entry name" value="Neural/ectodermal development factor IMP-L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051170">
        <property type="entry name" value="Neural/epithelial_adhesion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231">
        <property type="entry name" value="CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231:SF253">
        <property type="entry name" value="DPR-INTERACTING PROTEIN ETA, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="28"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="118"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY55968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24475" checksum="DCE85BDD1A7FC098" modified="2024-11-27" version="1">MLQLISWKSRLAKARFWNVKLVEVPLAIYWTKDGKRLLQSAYPSPLSVDAQDSTLGLGFTRSRLFVNCASHEDAGIYSCVAENEYIRAFKDSQVFVDETLDANNEIICLDKKPFVGIPARVHMWTHTRLEVMGKDAQLYCRSSGDPKPRVMWKGPDEEVITSSKKYKFLPNGDMIVRNIDWTDMGVYTCVATNSEGSDEAMVFLYPTMPENNIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHE8</accession>
    <name>A0AAV4UHE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger protein rotund</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rn_0</name>
        <name evidence="2" type="ORF">CEXT_35371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012869">
        <property type="protein sequence ID" value="GIY57189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="18905" checksum="A04F2A06F875AA3E" modified="2024-11-27" version="1">MGSPMSPPSHHLHPHVSETCLQNSMNDHHARLHMDPRHQQQQQQQQQQQQQQMVTNNANHINGRDHDLGSHLGQNQYDTSPMTQPHPPPTSKNTSAFTPIQSGMLPISSGPQLSMPSATRTSYFPYEPINFPKSTNPMGSMEVKQSHSSFPNQLISLHQIRTMHPCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKA0</accession>
    <name>A0AAV4UKA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_450601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013025">
        <property type="protein sequence ID" value="GIY58167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10941" checksum="A9CE65312CA0F061" modified="2024-11-27" version="1">MYFWECYLENPDVGIQSRYSKSHLPPCPLFPQDDPSHFRNEAIQNAFDFDPLICHLLTTSTEETPLEYRNFIPGHHLSLKRVSNTTLFLVITSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URI1</accession>
    <name>A0AAV4URI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_625491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013320">
        <property type="protein sequence ID" value="GIY60372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8990" checksum="C8532FBF8788616B" modified="2024-11-27" version="1">MDWKHGTRITNSKTRNLKNRTLKKDFKYKWGDMEHSLWPSTDFSKCKELEMDWETRHLFGILISFGIQYFCKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZC6</accession>
    <name>A0AAV4UZC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_205331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013704">
        <property type="protein sequence ID" value="GIY63098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17168" checksum="2B09C9293D7B9283" modified="2024-11-27" version="1">MCRQLCTAFKEIEVIDSIVENSKRSDLQQDYVQINETLLQKRKFLEEWVSRYHCPIESCKLHNSPKNLVNNVNCTVNNNVNNVVNCNYSKSVNASISSKVNVKPVVNSKHVTLANASNSGKVIGNIKPKTKRNASQISSNVNDSGEFRTLTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5A2</accession>
    <name>A0AAV4V5A2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_768871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013974">
        <property type="protein sequence ID" value="GIY65188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12843" checksum="6DAB556A98211EF2" modified="2024-11-27" version="1">MDVVVEVDKSPGEESFDDVTAQNIQELLMKEESNFESLALPATCDIHAKLFCTPISDYRKLNSVTEFDGYTMPYLQDFAHALHGSENVAEDEFQPPLSQVKLAILLVLNHKKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V840</accession>
    <name>A0AAV4V840_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_757111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014103">
        <property type="protein sequence ID" value="GIY66266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V840"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10675" checksum="5175D2AF1DD0ABD2" modified="2024-11-27" version="1">MERLFIRAESIQPVYPSCPNTKCQKDPDIFRKALHINCISRYLKKCAISYSNKQIYYLRQKSRLLVDARRKQQKIPLQIQYRVTERGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VB22</accession>
    <name>A0AAV4VB22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_242691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014250">
        <property type="protein sequence ID" value="GIY67492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VB22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9989" checksum="6BCB46400619D34B" modified="2024-11-27" version="1" fragment="single">MFEEIRLALSRLYFTEGHRHYIWYGGVKNYLLRQQITKGIQFEHVNHRALATKTICVSKISSPSSRMVELLQNEGFELSDSGASSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VF78</accession>
    <name>A0AAV4VF78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Biotinidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">BTD_1</name>
        <name evidence="1" type="ORF">CEXT_691991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014476">
        <property type="protein sequence ID" value="GIY69021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VF78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040154">
        <property type="entry name" value="Biotinidase/VNN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609">
        <property type="entry name" value="BIOTINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609:SF27">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9543" checksum="A0FB1B9B74B2E0F8" modified="2024-11-27" version="1">MFADQAPQMTSIQFWESWALGNNVTMLAANIQIPGYMAVGSGIFHGQDGALVYTFNPDGYSKLIVAKCAKARCRSSGTEGQYHSHLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJ90</accession>
    <name>A0AAV4VJ90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_305881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014641">
        <property type="protein sequence ID" value="GIY70257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJ90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9570" checksum="ED551E6A2B696704" modified="2024-11-27" version="1">MMEKGGETERELLVADALLQCLSHQTHSLTPPNFGSGREDTSVVDKHLPNSCYLTLYETAEAKSFAKEIFSKDNQMFDLQRFQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VS71</accession>
    <name>A0AAV4VS71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_250191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015030">
        <property type="protein sequence ID" value="GIY73076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VS71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9085" checksum="C1A706B4D4B8E190" modified="2024-11-27" version="1">MPRSLKKSMHHFRDYLSETKVTFSSLLNLSNADEQFPREKSQIFKLQDHPWSFIIRPSQGETSAPPLEHRPLSSDDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W370</accession>
    <name>A0AAV4W370_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cilia- and flagella-associated protein 298-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cfap298-a</name>
        <name evidence="2" type="ORF">CEXT_751171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFAP298 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015580">
        <property type="protein sequence ID" value="GIY77097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W370"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003352">
        <property type="term" value="P:regulation of cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021298">
        <property type="entry name" value="CFAP298"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13238:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13238">
        <property type="entry name" value="PROTEIN C21ORF59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11069">
        <property type="entry name" value="CFAP298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="32798" checksum="5C4BF04C78FE0ED8" modified="2024-11-27" version="1">MVKLHVKKADQSLFWFETQTSINVGDLLKTLVEIYNAKLKIERLSYEIEELSKHGVSFPTNMQGLTEQQISDLVLKDDWAQKNLSPSDYVINKDPMGKRNGLAPLPKYAEVLTKTTAEAKARVSQKMIEAGVCLTPDVIKDTLEVLRGAVSICYPMGLPSYEIIKLELEGKEELFGTQAGTEILDVDKCDLWWASKKLDNNKVLSDYVGKNEKSKIIVKLHKKGYGAPVKEPVMTEQQKKDLMMAEYHRQEELKKLEFDDDDSHLDSQWADSNKLKKIILRFEYNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7Z4</accession>
    <name>A0AAV4W7Z4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_424811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015811">
        <property type="protein sequence ID" value="GIY78862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7Z4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11260" checksum="D12C023C78DBE066" modified="2024-11-27" version="1">MGKNKKEQNTLLFLFGCVRDEKVRQSCCVRIAALLATVQAMVGNILLRSNAGLFHSAGGCHLASGTETQWYAIPMSGTVRMGQIIKTCRTIEKYNSKKKLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBC1</accession>
    <name>A0AAV4WBC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_525131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015971">
        <property type="protein sequence ID" value="GIY80136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9412" checksum="36E5D2B6CE95DC3D" modified="2024-11-27" version="1">MANVGNLSPGTSNGKTGISNRLEIEMVQVPIELPSAAVPGSLNCVCPLNTGRLHSLVPQHVFFEWMEDFELPARADPRNRPWLDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WN95</accession>
    <name>A0AAV4WN95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_562871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016499">
        <property type="protein sequence ID" value="GIY84292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WN95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21543" checksum="D43342ED28C63950" modified="2024-11-27" version="1">MRKLTPNDSVSKRSNRIHKVETLLGDSTTEELTDRDFFGFLNQKKLSDVCIKGIATRKCRSKYGLKKYLLEVKLIESTMKITSSPKYFAKTKCGFIHTDNIKCKVGTVEGTERKSFKEKAQSTNLFAAPSTHLSNSIAKVPLLEFLQIDPVFTTSWRQEHFFFSERSLISIFFFFSSDAFRIHSTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPE0</accession>
    <name>A0AAV4WPE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_513671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016403">
        <property type="protein sequence ID" value="GIY83599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8316" checksum="DA80A81C7304403D" modified="2024-11-27" version="1">MKYRHRLLPRSANTKIMSGDPFVPKFAAVKAHLEAGATVSHIDADYDRANMNYYSFAIDVAISLTSLGWKFPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUZ4</accession>
    <name>A0AAV4WUZ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Nop16</name>
        <name evidence="6" type="ORF">CEXT_564241</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016681">
        <property type="protein sequence ID" value="GIY85711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY85711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13606" checksum="6BDEA9BE227AC3ED" modified="2024-11-27" version="1">MGRASGVSRRRKKKFNYNKNLKKLHKKLITLPKVRCKQIKEAWDTSKSYTRNMVEMGLSDDPNKTIGLREKKPMIRMPTLLFWRFPSFPSFCMASAFTFLHFQVTPSISFPYFCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVA1</accession>
    <name>A0AAV4WVA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_759941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016666">
        <property type="protein sequence ID" value="GIY85564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12850" checksum="58D24FCE5B5CB08A" modified="2024-11-27" version="1">MRNTWLKGLRLIGCFNAECAPWLKRLPKRIMRLIGASTRNVHLVERTAKRIMRLIGSTWNVHLCQRNMDYAPLVERAAKRIMRLIGANVHLVERAAKRIQSGMCTWLKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYG9</accession>
    <name>A0AAV4WYG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA helicase aquarius</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AQR</name>
        <name evidence="2" type="ORF">CEXT_60401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016931">
        <property type="protein sequence ID" value="GIY87373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="1">
        <location>
            <begin position="68"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="35844" checksum="7EE4B6292EA91038" modified="2024-11-27" version="1">MDHLRKGFTDYKIQVNVDDPKKLVPPFKIKFLPSEENIKKLVITPHVLPSRGPYLYEKPKMNMIQFTPTQIEAIRSGMQLGLTMVVGPPGTGKTDVAVQIISNLYHNFPNQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEESLETEKDFSRYGRVNFVLAKRLDLLNEVQRLQESLNVPGDVSYTCETAGHFYLYHVLARWEEFLSKVKPGTSKKVPVAKIAEYFPFSKFFDNAPQPLFLGINYKEDMEKAEGCFRYIKKIFSQLEEFRAFELLRSGLDRSKYLLVKEAKIIAMTCTHAALKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5V2</accession>
    <name>A0AAV4X5V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_244231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017176">
        <property type="protein sequence ID" value="GIY89178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11646" checksum="B2E3FB0ED1E07980" modified="2024-11-27" version="1">MSSGRFFFYVVIVLRFWEEEDLWNYGYSGTDGGVDKILLSWTPGVVGGIETSLGQREAVGSVPGVVAPCPRQLICEGSEQIVEGPRYDGIVVHAHVQVNETDGISNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5Z3</accession>
    <name>A0AAV4X5Z3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_136571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017337">
        <property type="protein sequence ID" value="GIY90640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5Z3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="17282" checksum="235E0FA369732617" modified="2024-11-27" version="1">MIEKDFCNFLGFWIVRVEHMHLGRKATQIISRPSFNPRFREYSLCYFESFGEHRIRVYEVNSACKHLQAKNQNKKNATVFAEEQYSSPRIKRHPSRLRRLFSYSDQGDTVFSMIVIFSATLPTPCTELSQIMQRRLLSVRLVDDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X607</accession>
    <name>A0AAV4X607_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutamine--fructose-6-phosphate aminotransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GFPT2</name>
        <name evidence="1" type="ORF">CEXT_334211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017334">
        <property type="protein sequence ID" value="GIY90627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X607"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9822" checksum="8A4306FA6B1A0DC6" modified="2024-11-27" version="1">MHSEGILAGELKHGPLALVIDDAMPVIMVVTKDPVYTEVHECFATVPHTVDCLQGILTVIPMQLLSFHIAVLRECNVDCPRNLAQVGDCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7B0</accession>
    <name>A0AAV4X7B0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_428301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017322">
        <property type="protein sequence ID" value="GIY90482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7B0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY90482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13277" checksum="5A57C417DDAF02B7" modified="2024-11-27" version="1">MHSSFYALPVAEIGGCNFRPIGNRMAEFLAIYSGGSPFAERSGRLASDKASNAHPLQNRKKKEGSRAGFTLDLGSDLRIKANSHRIFKRNRICYWKKERISEKIRRGIWRVPLRVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9V2</accession>
    <name>A0AAV4X9V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_622871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017475">
        <property type="protein sequence ID" value="GIY91927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13222" checksum="A1639B4E68D8AACE" modified="2024-11-27" version="1">MLPSEYASIFNSKKTSFITKQVNLNEDKAINVLPTVITDAKKHEDDIHLKDPPSPMKQTIDLNTNRISDDKLRVRHCKTNTAVTQTVGSAEKPMRKISNASCEHDSEESSHFSGIKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB73</accession>
    <name>A0AAV4XB73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_671661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000011">
        <property type="protein sequence ID" value="GIY91445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15342" checksum="7DC026E8C71E37BD" modified="2024-11-27" version="1">MGVCQRRCYLADDYTFRSLNKGSPLTPPNLHSLPRSFSPADHKLVPVLRSPKHSLCRSQGRTNHRCYLVARVQLLMHRQSNRYSLRQMQKVSSILCGEKKDTVAALFVATQFLKHQNIGIQFRCGTLNCSRKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD50</accession>
    <name>A0AAV4XD50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_560891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017634">
        <property type="protein sequence ID" value="GIY93171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19818" checksum="7D080CD68F2382B0" modified="2024-11-27" version="1">MKPLSDVQTLLLIIAVTREQLISFICYNSSIEMILCYDNNTDPNTSSLLLLIERSNSGHQSVEKSTKDFDCQTCLVIGAKDASTSTDDLEYFDEGHGDEEADLLDEAMALQQPNFVPPVNLNPFMNPFYEFLAFDDPLDYLWDTELDGERVCAQWILKSTTVSFLNKETYHRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD86</accession>
    <name>A0AAV4XD86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Unconventional myosin-XV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Myo15a</name>
        <name evidence="2" type="ORF">CEXT_777281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000222">
        <property type="protein sequence ID" value="GIY93027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.530">
        <property type="entry name" value="MyTH4 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000857">
        <property type="entry name" value="MyTH4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038185">
        <property type="entry name" value="MyTH4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051567">
        <property type="entry name" value="Unconventional_Myosin_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692">
        <property type="entry name" value="MYOSIN VII, XV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692:SF26">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00784">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00139">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51016">
        <property type="entry name" value="MYTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MyTH4" evidence="1">
        <location>
            <begin position="124"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="339" mass="39442" checksum="BC89AB551D7A830A" modified="2024-11-27" version="1" fragment="single">MLCERNGINGVECVCVFRSKPFWRENVKLTALRWRGSRRGPTRRTGRASRAVAGVNHLEIPAELAFIFSKLDEWQCVHNERNVTKVVGEVAKSVYPEYRLPSDIDQHAFTKFTNVYFKAHIWGMKREPIKTPFLAKTNESDYQCSLALFKLILRFMNDNNLSGKKERILGDYIVQKGLLNETMRDEIICQLCNQTWKNDNEANNERAWILMANCLSCFAPSRHLYKYLLKYVSDHAYDGYKAHCQRKLLQIQKLEPEGRRTYPPCLLEWKSNTRRTNMALEARFADDVAVRRFPRGRFTKARAARGREHSITQMFDKETAEHEIKSSGLAPHLYSLANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEA6</accession>
    <name>A0AAV4XEA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_445091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000101">
        <property type="protein sequence ID" value="GIY92133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15668" checksum="2FE04BA480BC0E3D" modified="2024-11-27" version="1">MLKSPQEPNDLKRSKIIHLNPPRTVVFSSVSDMDEKLFNRVLLFPSCCYCSVYYLSRGFGSRYVELQCSSINLKEKSSKNPQKLLQVGVCIDYRQNYCAVWQDSLQSGERWICCIFVVSVAFEKNIYLYDLNKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGP4</accession>
    <name>A0AAV4XGP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_419951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017646">
        <property type="protein sequence ID" value="GIY93239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10392" checksum="7580D923EB77201E" modified="2024-11-27" version="1">MGDVFNPRLESHWNPICQVSEKCVLLAILNSSCLSKQKGKKGSLQSKTRRVSLRIHPKQIHRTIANSIKAAKQKPSSSWGHSSEKATPNASKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHI9</accession>
    <name>A0AAV4XHI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_73291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000408">
        <property type="protein sequence ID" value="GIY94597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12440" checksum="986AE36733EF9A2C" modified="2024-11-27" version="1">MRSQITFNFKIPFPYKEQIKLNFPKSGTKVVVRRKPQFDGNGAESIRNLHFFQEKTACKSPPLHSRAIKRYYPSFQQTIRERWIPPLMQATPSEAEGLMTENGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM42</accession>
    <name>A0AAV4XM42_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HUS1</name>
        <name evidence="5" type="ORF">CEXT_48931</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000632">
        <property type="protein sequence ID" value="GIY96187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY96187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="273" mass="31427" checksum="F951219FE7D3801D" modified="2024-11-27" version="1">MKFRGKMVEISSIQHFTRILNTVGKLTKIAVLKIIPSHMYLTFNERITSGGSSLWCEIPQDHYFCEFNMEGLSPENNEIYLEFQIENLITAFKSAQAAKSIKLKLTKKHVPCLTLEVELPSLHSNSRCVVHDVPVLVIPRRLWEQFQEPSMIQFDVSIYMPSLKIVRSVVERMKNVGTFMTMFASSDGEIDLRCETDTVTITTHFKDLNLTSVSAHTSDKIKAECRIDIRKFNQFLFGQQINPAKVVCNITHHQMVQFSSCMMMFQFNISYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNX9</accession>
    <name>A0AAV4XNX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_426811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017922">
        <property type="protein sequence ID" value="GIY95509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15783" checksum="EA8644747DB07253" modified="2024-11-27" version="1">MKVCFAGNPIATFHFQLPNRELPVKANYNRINGRQLSHLCAAATVPFGTDSEEEQNISKRSKEKFSKNIFPLLFWAKRKYFEAKGGSITAVPLKFRQVFNLSCKGASARPVDESLFRRKSNRHISLPAPQQRITSESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XS82</accession>
    <name>A0AAV4XS82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_270451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018085">
        <property type="protein sequence ID" value="GIY96764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XS82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12726" checksum="AFF32B0BFBCC8BCB" modified="2024-11-27" version="1">MFPGTQLKHQHSKHLYRRGLFAKRKSTSTITKLFVIWEKVAIPKLYHWNDWRNFGLNLSVANFQRQKKITISTPSPSPKFSPYLYVAPPFPPNTSQTIPDIYPLLKVASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSA8</accession>
    <name>A0AAV4XSA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_306971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000876">
        <property type="protein sequence ID" value="GIY98062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10843" checksum="085E63D47604E804" modified="2024-11-27" version="1">MKSTLFYSKKKSIYTDAKKKKRRISAEMESKDLDIITFGTPWHHKNSHIREVSSLTPPCLSACWENSSSRSASPAIVTLPVTQGCCTQSARTGSHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XW99</accession>
    <name>A0AAV4XW99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_288931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001028">
        <property type="protein sequence ID" value="GIY99282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XW99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9684" checksum="F76016B99540B803" modified="2024-11-27" version="1">MRVIDYSFEKHVRWMGLALFPPLRKMAVDTTMPRLFRRCLLKLSMIGNRNEGDGRSPTFSYLTGNHLELWNLHPVVTGLIVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXR5</accession>
    <name>A0AAV4XXR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_651561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018380">
        <property type="protein sequence ID" value="GIY99083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13355" checksum="8C141E1A33A1E016" modified="2024-11-27" version="1">MMPAPSLTTQKTETGDSYEGDSPTIFSSGSENGYIITDSKLAKDALLGTILAVIFLSEELCNVQTQKGSFVSDPHPLPSYIREELTDFPPYRFMVLIHSIAGGTLGDSLTKLFSSFAQLTMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYV3</accession>
    <name>A0AAV4XYV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxidasin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Pxdn_3</name>
        <name evidence="3" type="ORF">CEXT_88851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001007">
        <property type="protein sequence ID" value="GIY99121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20957">
        <property type="entry name" value="IgC2_3_Dscam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001049">
        <property type="entry name" value="Down syndrome cell adhesion molecule-like protein Dscam2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY99121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11204" checksum="1483B1A3247033D2" modified="2024-11-27" version="1">MFPCIAPLIVNMRPPRQVLNIGQEATFNCNVTGYPVHTITWKKDQRPLASSSRVRLLSRDVLHITSVRRDDRGMYQCFVYNDLDGAQGTAELKISGILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0J6</accession>
    <name>A0AAV4Y0J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_216391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018604">
        <property type="protein sequence ID" value="GIZ00946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19911" checksum="02332B1E3BD0985E" modified="2024-11-27" version="1">MVTKSMDMIYKMIQQSCGVNSQSRLMSDSTVVGIDSQSCVIWDSTIMWCQHQSRLMSDSTVVWYQQSVMCYMGFNNYVVSTEAIRKIIENYVGSETTVTANYFIKSELFRKKSAYMRQAKPKRFCFLFASVHACRTFFTLNWVPVPVPKFLTAVATSLCSTPLEREFLANILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1E0</accession>
    <name>A0AAV4Y1E0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001085">
        <property type="protein sequence ID" value="GIY99795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1E0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8885" checksum="B7A9F6EA01196CB1" modified="2024-11-27" version="1">MEFLSIGRSRVHHRDLTSKLRILRREETVQSERLQSTEKSVMDNSRQLMAAELLLERYRQEFINSTSDCPTTLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3A0</accession>
    <name>A0AAV4Y3A0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="33">Flavin-containing monooxygenase</fullName>
            <ecNumber evidence="33">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="35" type="primary">FMO5</name>
        <name evidence="35" type="ORF">CEXT_127351</name>
    </gene>
    <organism evidence="35 36">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="35 36" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="18">Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms. Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects.</text>
    </comment>
    <comment type="function">
        <text evidence="19">Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>(2E)-geranial + NADPH + O2 + H(+) = (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54860"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:138375"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="29">
            <dbReference type="Rhea" id="RHEA:54861"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="31">
            <text>N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:24468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16269"/>
            <dbReference type="ChEBI" id="CHEBI:17735"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="31">
            <dbReference type="Rhea" id="RHEA:24469"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>NADPH + O2 + H(+) = H2O2 + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:11260"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.6.3.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:11261"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>heptan-2-one + NADPH + O2 + H(+) = pentyl acetate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54836"/>
            <dbReference type="ChEBI" id="CHEBI:5672"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:87362"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:54837"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="30">
            <text>heptan-4-one + NADPH + O2 + H(+) = propyl butanoate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:89484"/>
            <dbReference type="ChEBI" id="CHEBI:89719"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="30">
            <dbReference type="Rhea" id="RHEA:54853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>hexan-3-one + NADPH + O2 + H(+) = ethyl butanoate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54844"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:88764"/>
            <dbReference type="ChEBI" id="CHEBI:89891"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:54845"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>hexan-3-one + NADPH + O2 + H(+) = propyl propanoate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54848"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:89828"/>
            <dbReference type="ChEBI" id="CHEBI:89891"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:54849"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>hypotaurine + NADH + O2 + H(+) = taurine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:74111"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57853"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:507393"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:74112"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>hypotaurine + NADPH + O2 + H(+) = taurine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:69819"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57853"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:507393"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:69820"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>octan-3-one + NADPH + O2 + H(+) = ethyl hexanoate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:80946"/>
            <dbReference type="ChEBI" id="CHEBI:86055"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="28">
            <dbReference type="Rhea" id="RHEA:54857"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="32">
            <text>octan-3-one + NADPH + O2 + H(+) = pentyl propanoate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:80946"/>
            <dbReference type="ChEBI" id="CHEBI:87373"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="32">
            <dbReference type="Rhea" id="RHEA:54841"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>sulcatone + NADPH + O2 + H(+) = 4-methylpent-3-en-1-yl acetate + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:54864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16310"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:138373"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:54865"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>trimethylamine + NADPH + O2 = trimethylamine N-oxide + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:31979"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15724"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58389"/>
            <dbReference type="EC" id="1.14.13.148"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="27">
            <dbReference type="Rhea" id="RHEA:31980"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 33">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 33">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="35">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="33"/>
    <dbReference type="EMBL" id="BPLR01001220">
        <property type="protein sequence ID" value="GIZ00896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3A0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016174">
        <property type="term" value="F:NAD(P)H oxidase H2O2-forming activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034899">
        <property type="term" value="F:trimethylamine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000159">
        <property type="entry name" value="Dimethylaniline monooxygenase [N-oxide-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002257">
        <property type="entry name" value="Flavin_mOase_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01125">
        <property type="entry name" value="FMOXYGENASE5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 33" id="KW-0274">FAD</keyword>
    <keyword evidence="7 33" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="17 34" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="11" id="KW-0492">Microsome</keyword>
    <keyword evidence="15 33 35" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="14 33" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="36" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 34" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 34" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="34">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00045957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00047855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00047864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00047977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00048041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00048088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00048459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00048989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00048990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00049443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00049475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="RuleBase" id="RU361177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="35">
        <source>
            <dbReference type="EMBL" id="GIZ00896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="36">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="611" mass="69453" checksum="955AF0EB0D92DD1B" modified="2024-11-27" version="1">MCARDETHVHITSTPYHYWTALKLITLFPQNCIINRWRHEVLLNHSDAIVRPQPTSFVSTFLLPNFLSPRSASSERMEVTKRVAVIGAGPCGLGAVKSLKDEGLEPVCFERTGQMGGLWRYHDEDMDGVASVMKTTIINTSKEIGACSLCPPPAEYPNYMHHTLMYKYICMLAEQGDCVRHIKFYHETKKIEKAEDYEKTGRWTVTCKNTQTGELVTDTFDAVCVCIGHHVYPNEPTFPKQEEFEGKIMHTHSLKKVDGYEDLKIVVVGVGNSGMDAAVELSAVAKKVYLSSRRGTWVLPRVGPKGHPFDAIFIRRYLHLLQKILPFNLICYVTEKQINDRFNHDMYNLTPDHRILSQHPTVSDTLPIKLLSGTVVIRGGIKHFTKKGVVFDGEEEETDVDAVILATGYKIKFSFLSDDILPVEDNKVRLYKFIFPPHLPHPTLAILGLIQPSGPGFPVGEMQCRWTARIMSGNLNLPSEVAMNADIDKKLEYIRKRYVDSPRHTLQVDFISYQDELAEEIGAKPNLLKLALTDPKLFWVIFTGPSLAYQYRLQGPHTWSGARDAILTYKERVVAPLLKPGQKYRKYGGAKIMKLLYLLPILYLFYILFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6S9</accession>
    <name>A0AAV4Y6S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphatidylethanolamine-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PEBP1</name>
        <name evidence="1" type="ORF">CEXT_224131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018767">
        <property type="protein sequence ID" value="GIZ02174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.280.10:FF:000006">
        <property type="entry name" value="protein D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF147">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20321" checksum="0840B460A7E19147" modified="2024-11-27" version="1">MFEDAGIVPDVIDVAPPYVAEVRYNDNVVNLGNELTPTQVKDPPTHINWPIEEDAFYTLCMTDPDAPSRANPKYREWHHWLVVNIPGTNVTEGMVMSEYVGSGPPQGTGLHRYVFLVYKQPGTINPDEKKLSNRSGDHRGRFKIANFARKYHLSNPIAGNFYQAQWDDYVPKLYEQLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y705</accession>
    <name>A0AAV4Y705_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_637231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001546">
        <property type="protein sequence ID" value="GIZ03057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y705"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16188" checksum="D0BA40529CD7785A" modified="2024-11-27" version="1">MRNGEELNPPHNGLTDKHQVHHALLVFFWEEWEEFRLKVFISSVEKTNCELKVISATTIINSEKTSLKNEKNLKATQKLLNPTRDLSTASGDYDCDSEFSFPTSRSSLKTNTGKNTKMRKRKETKRRGKTIRYSAKGNLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M730</accession>
    <name>A0AAV4M730_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NHP2</name>
        <name evidence="8" type="ORF">CEXT_390061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001933">
        <property type="protein sequence ID" value="GIX68184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M730"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="7">
        <location>
            <begin position="39"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX68184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16919" checksum="419081D25E5985C5" modified="2024-11-27" version="1">MENTLNEETEETTPLTYEQQLAFVSVIAKPIANKKLTKKLYKLIRKASELKSIRHGLRDVQTSIRKGETGIVVFAGDVTPIEIMCHMPAVCEEKGIDYVYTPSKAEIGLAMGVRRNCLMILIKEHSEYAEQYSDCKNRMKSAFKEAFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7K8</accession>
    <name>A0AAV4M7K8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_12335_1</name>
        <name evidence="4" type="ORF">CEXT_777861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001939">
        <property type="protein sequence ID" value="GIX68230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7K8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF26">
        <property type="entry name" value="RE23625P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00299">
        <property type="entry name" value="ACRYSTALLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="155"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX68230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="261" mass="30302" checksum="0E5C65B53F258C0A" modified="2024-11-27" version="1">MSIMHVDLIFKNYLELSRPPSLSFSQGHRELNITTEIPARNKWSARVVLEAERKKLDIRDIYCYCMYTTILGFLELLSETMSFERRLPLLRTDFSVIDREFSSIREKFDQEMKLMEEEMNRFRSQLMDREVPRIQSHTAATGADGTTTHRSEVRTWLDGLSSPLIQDSDDGKKLRLRFDVSQYQPEEIVVKTVDNKLQVQAKHEEKTDTKSVYREYNREFLLPKGTNPEAIKSSLSTDGVLTVEAPLPALEGIHMIPIENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M803</accession>
    <name>A0AAV4M803_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_632091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019410">
        <property type="protein sequence ID" value="GIX67526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M803"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7562" checksum="FB0A5A992B6ACB7B" modified="2024-11-27" version="1">MSGRGSPLPDTETMDVSPPGDNEQPPYRLPQDPPLGSDEFLYLHVKTITRIIELKVKLLADWFRPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9B5</accession>
    <name>A0AAV4M9B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_628411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019448">
        <property type="protein sequence ID" value="GIX67976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043853711" evidence="1">
        <location>
            <begin position="21"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12423" checksum="2E506A7FA8694D58" modified="2024-11-27" version="1">MERFCCYRVYFLVVLRLVLTEHAFSVRRVTEIETKLIEDVCPYNETLELFLSSSGTQSAIRLKDMMTKHSNCTIKIDSALTGVILNFSYKSGSTYDGCQNFIQDKSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEM5</accession>
    <name>A0AAV4MEM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_278721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019681">
        <property type="protein sequence ID" value="GIX70491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9666" checksum="E37682CBDB72DA4C" modified="2024-11-27" version="1">MASQRADKRELPDSSHHDDRYGERLKAKLEQQAASIVGRRSNNGGLRSELKTEFADNAKVNGIRQERKERKNFSSTSPVTKDVGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHD9</accession>
    <name>A0AAV4MHD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_197241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019658">
        <property type="protein sequence ID" value="GIX70214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9659" checksum="AD3E27796A11BEC7" modified="2024-11-27" version="1">MKTIQIARKGQHQESSETFASCLANIANCSADISPTIILYSYQMRGFIYFYRPLMRPGNRCGDDTEEIHRIVVGYPIADVDRASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MID6</accession>
    <name>A0AAV4MID6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease Dicer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dicer1</name>
        <name evidence="2" type="ORF">CEXT_763391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002253">
        <property type="protein sequence ID" value="GIX71781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MID6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051363">
        <property type="entry name" value="RLR_Helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14074:SF16">
        <property type="entry name" value="ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14074">
        <property type="entry name" value="HELICASE WITH DEATH DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="23967" checksum="7299DDDD9526F32F" modified="2024-11-27" version="1">MEKRIFFLVPTVPLVTQQAKTIRDHTDLKVKGYYGEMDVDSWDKDKWIEEFQNHEVLVMTAEIFRIIVDHAFIPLKRIQLLIIDECHRAQGEHPYRQALKCFGTLSLEEMPRIFGLSASLLNGKCKSSKLEKCLRELEMTLRSTIVTASDISDICKYGTDPDEYIILYEKYEISSTLNNECLDVISEIKLSKPDEKENSRKKNLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJM8</accession>
    <name>A0AAV4MJM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_459001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019708">
        <property type="protein sequence ID" value="GIX71009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7820" checksum="A346579721A40914" modified="2024-11-27" version="1">MCLKHNPRIIKSAISPGCIIFQITDVTVIKVGNVPLPHIYGGNNLYMDNPMMLPFPMMTDRHGRIRGLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKR1</accession>
    <name>A0AAV4MKR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_67631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002375">
        <property type="protein sequence ID" value="GIX73102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8268" checksum="1D1CEC7A5C67950B" modified="2024-11-27" version="1">MRILSSSVLDFRSAPEIMEWLGNYVAPTSNKPSPEVTSGRHFLRSPIAALLSQETLHEKQQQKEKEREGGNCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPS2</accession>
    <name>A0AAV4MPS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_453261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020065">
        <property type="protein sequence ID" value="GIX74394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="24405" checksum="6C352B78DC5983A5" modified="2024-11-27" version="1">MVSVSRRLAMKKVGGATDNEIVFCFAREVDAFVTEEKLGRVRIQNTYTTIYFVLGLYAWNGRTICEEDLCVSKSDAKILKFSLQMGKISCMIYLETSNSDAERDFNNCRPLSVIYPFHSSPSPQLKLGQSSGNQTEWRAVNHRASETVKTPSVLLSLQLLGCPELLLALKGEMELPKVTERARKSWGFNDVVAIIDTCVPLVRIDKLLLPITSCRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUK3</accession>
    <name>A0AAV4MUK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_591201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020186">
        <property type="protein sequence ID" value="GIX75630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="20103" checksum="87BE507A66D2D734" modified="2024-11-27" version="1">MPKNNKSFFENIHTYYAQLNKPIKKIKINEFVSHSNNILSKPIRIFPLRTTHPPISIPSYQITQHRRRIETHRPIGETKYEFHLESKFECEFGLSPAWLPIFREINVGSGPMKSLSPTNEMQRSNIYADWPFEGPFRRSMPVDFDLQPPFSSPLNAQCPSKMGWWRNGERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUS4</accession>
    <name>A0AAV4MUS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_719161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002643">
        <property type="protein sequence ID" value="GIX76043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14535" checksum="CADD199C8DE57F32" modified="2024-11-27" version="1">MDICQRHVKDVRGRNIPAPWGATESLIEHFSKPSNALGLCRISKRYRYPHIHAKRGKALFEPNPFLSSPDDLPAVAQLNLKKLLIKNRSYGITPKGEAKNASETRIVSNISNVQHAPNNGRPPCRERNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXA0</accession>
    <name>A0AAV4MXA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">FMRFamide-activated amiloride-sensitive sodium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FANA_1</name>
        <name evidence="13" type="ORF">CEXT_633081</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020296">
        <property type="protein sequence ID" value="GIX77023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX77023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14786" checksum="FDB9CD3413BA0E56" modified="2024-11-27" version="1">MEVNDRIQNSSVYAISQIGYSKTSCSKITWISILTGALIGCCYQIYGFIDQYFKYPVIVDLLIEQPENITFPAVTICNLNRMKSEYEPCVYNIDALKKCHFGRTCWSFRWISFVIRTTKHSHMQNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZF6</accession>
    <name>A0AAV4MZF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_624131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002739">
        <property type="protein sequence ID" value="GIX77316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12023" checksum="E69858D1931DC386" modified="2024-11-27" version="1">MQLGDHLTRKKAAHDSQSGQSRQMHNRSQASNLSWRRQNLFIKKSPPPPLHFRLSSIPNCSGPLKISLRKGKPFVNLSLMENVTRFQVMTNQKFPFHLFTLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N088</accession>
    <name>A0AAV4N088_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 3A28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CYP3A28_0</name>
        <name evidence="7" type="ORF">CEXT_650261</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020325">
        <property type="protein sequence ID" value="GIX77403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N088"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050705">
        <property type="entry name" value="Cytochrome_P450_3A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302:SF15">
        <property type="entry name" value="FATTY-ACID PEROXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX77403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="31653" checksum="023EEA77D86E6176" modified="2024-11-27" version="1">MALRLESLETTSLRSKRDYCLQVLKTMFFFLERKWDSRPRAKHLVWKYVGIQKISFRSLNMLWTWMNRIRLMLINKGTNPIKELIGSVKAVIAMRRKNKESGRPDLLQLMIDAEIGDLSKVTSDDLTAKDDTEVDVKEKKRELDYYSVNKLQYLDQVLQESLRIYPPVYLFVSRECGEDIDLGKIKMKKVMGIQVPSYHLHRDPELWGPDANEFKPESRIWWSRRETKGEILSLVTFIKTSYDALFTRHCAQFREAPVKTTICIQKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0D8</accession>
    <name>A0AAV4N0D8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium channel protein para</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">para</name>
        <name evidence="7" type="ORF">CEXT_721651</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020396">
        <property type="protein sequence ID" value="GIX78247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0D8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0086010">
        <property type="term" value="P:membrane depolarization during action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019228">
        <property type="term" value="P:neuronal action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF288">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN PARA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="6">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX78247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17238" checksum="2287F94A1C5FAE8B" modified="2024-11-27" version="1">MIMISSLALAAEDVNLKYRPGLENVLTYMDKVFTVLFFFEMLVKWLALGFRKYFQNAWCWLDFVIVLVSIFNLSVGLMGYGNIPAFKTMRTLRALRPLRALSRLEGMTTEVGGGNIQAFKTMPNPPCPAATAGPLAISRNEGGCKRADSSHTSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBQ6</accession>
    <name>A0AAV4NBQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_85357_1</name>
        <name evidence="2" type="ORF">CEXT_564001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020652">
        <property type="protein sequence ID" value="GIX81086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="25742" checksum="3322F3A478F68A10" modified="2024-11-27" version="1">MLDFNRRVFNRRFQSKSSRVPIDQKLILHPLCSRSKPLFQLLKAYPDWIFNVDGNVVAREMESGLKNEMPQKTSEEELLELAKKELLRDIKCASLRAEQYGAHSWAKPQHYAPSKRFLKHMLISASKDNDRREQQTLESRERAIKHINSPHKHSKDVRKRNRDNYIENETKNSKKHKNYHGENKESFLNNEKKSFSKNRKKDKGEKYSVKRKHSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NID9</accession>
    <name>A0AAV4NID9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_753641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020975">
        <property type="protein sequence ID" value="GIX84520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NID9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9790" checksum="FF002D6B2D63F557" modified="2024-11-27" version="1">MTYKLINESITPPLIFQEQLNKKKSRRYRPTHLPLALRKCPQVKRATPFSGSTEECLACLECILTFVFVINSTPLPLIFDVTESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLQ2</accession>
    <name>A0AAV4NLQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_731601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003540">
        <property type="protein sequence ID" value="GIX85735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9060" checksum="B4E3EABF462F357C" modified="2024-11-27" version="1">MAFPNSPVTVSDLSFTILLLRNVPPIMDYIPRNWALQFHEIGHVLHRNWGKGGNVLRFRALLSPGFFWSGDYGNSITLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTB4</accession>
    <name>A0AAV4NTB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_16191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003730">
        <property type="protein sequence ID" value="GIX88044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13334" checksum="2BD4C2EEBE442C0B" modified="2024-11-27" version="1">MGFKDAGCSDGKIARNILVNRFLLNPAIMARNSEQEEQKIISWRQRVTAWYPCKGKGALSMVLAVTVVTVMAIFIMSQEKTLPRNRTIIYRFSLSLQRQQATSLGMERSICHSGINKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZB6</accession>
    <name>A0AAV4NZB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_35591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003914">
        <property type="protein sequence ID" value="GIX90129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18168" checksum="2C11EB21D12A6BA7" modified="2024-11-27" version="1">MSTVAPLVKQVRHNFSKVPPALQSAGVYIPSESFIFFGAYKCMDPLLLLRNRVGLKGKKRAYKCMDPLLLLRNRVQGRKEKKRDKEWVFRQTEMRSGNFDGNVLLKSFVFQKDQSEKQKIASAVTTTALWKSRALSTTLSVPTPSGHSFMVHLHGENASSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCY0</accession>
    <name>A0AAV4PCY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_465251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004326">
        <property type="protein sequence ID" value="GIX94011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="10050" checksum="6228A44953C95B8C" modified="2024-11-27" version="1">MFPLFVEENKLLFDFPEFDKEFSQIYIREQKEKKKKKVDLESQSRDGRSRWRHLERKGNEEKRKNRNSVLNRKGNIHQEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDC0</accession>
    <name>A0AAV4PDC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_95051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004395">
        <property type="protein sequence ID" value="GIX94579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14054" checksum="1A7260FA741D25A5" modified="2024-11-27" version="1">MEPHLFPVTWCLCDPYSSSYSISLKYHPTVDCLGAGGGRMGEWDYGNESHHRRVTLPVLIYCLANPCHGLNDVKKQVPTAGFTIALDVLPCFFSSSARLYSFRVVTTTEKEELLVVGNLSQVNNVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKB8</accession>
    <name>A0AAV4PKB8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_402281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004545">
        <property type="protein sequence ID" value="GIX95637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10037" checksum="98F5624F221282CA" modified="2024-11-27" version="1">MPSLLSLVGWLLDSLCTLTCLVLFPTFSPSSVSPSLMPQGSGHTGKDSSLSLLHSLSFFLAFCLSLPAFCLHFSSMYALLQVYTVCLRIQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLF0</accession>
    <name>A0AAV4PLF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_6301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004743">
        <property type="protein sequence ID" value="GIX97133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12855" checksum="0EE6195E758B9342" modified="2024-11-27" version="1">MSLYLPSLEPGTFRVLGGCDNHYTIGTTIGIEFSCQICFLADKHHVTASKFQFVISVYQHKFYYQDSYKQAPNSYITICLLREEDEGRGAEQQGDGQHRPGEGPPRQHQQASGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWH1</accession>
    <name>A0AAV4PWH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_270609_1</name>
        <name evidence="1" type="ORF">CEXT_332091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005389">
        <property type="protein sequence ID" value="GIY01928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="16248" checksum="1549208A0CD9B537" modified="2024-11-27" version="1">MWEIENLGICDSEKSESDKQVIERFEKNLKFVDNRYETGLLWKRDTEDLSDNFDLARRQFNKVRKEFKNDTFVKEQLMEVIKYQKEHNIMQECGENEKGYFMPFRAVVCKDKVPKSEWCLIAVVVQNQGPNLNPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWR6</accession>
    <name>A0AAV4PWR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_700751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005303">
        <property type="protein sequence ID" value="GIY01351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8899" checksum="2EAFA8308284D95C" modified="2024-11-27" version="1">MKWQLKPDTAQYTESISNESFKLNSTLSIRLHPIELADNLFGRAMTFDAAQQLTVLDRFGPSYHCFYSAVAIRFDHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFY4</accession>
    <name>A0AAV4QFY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_267221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006057">
        <property type="protein sequence ID" value="GIY07167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11822" checksum="7769FED27B523512" modified="2024-11-27" version="1">MADSETTIVEYRQSTPVLIHAAPQAPGTGKLSLNISVPRSGECPYETETLLIRPESIVSRRTIRAPKSIDFLSNVRTSSLALLGNSQDDRRHLKVRRVPQAPRTDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHU9</accession>
    <name>A0AAV4QHU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_211371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006164">
        <property type="protein sequence ID" value="GIY07839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11871" checksum="12CB4F0CF4A8A49F" modified="2024-11-27" version="1">MGSTEVAVSDVTRLCNYYLRLESTCGFYCRRCFQKFGLCTYATTIWDSNPLLGYFAVAVFRLDEIMHLCNYYLRFESTCGFYTRRCFPKFGLCTYATTIWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJU9</accession>
    <name>A0AAV4QJU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006261">
        <property type="protein sequence ID" value="GIY08522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="21634" checksum="0A24C1B5E45FCE4D" modified="2024-11-27" version="1">MSIIQSLVSVIAAHFGTHFDFEKPKLEVSTGTSSLATLSHLHNYFGICISMFNRNNVAISSPHLKKEHYTESNLQPMLKRTSQNIPRQDRRLTSIIQSLASVIGAHFVEHSDFEKPKLEVSTGTSSRATLSHLHSYSGICISMFNRNNAAISSPHLKKKHYTESNLQPMLKKNVTKYSPARQRWRRGGGILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMH1</accession>
    <name>A0AAV4QMH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_630161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006622">
        <property type="protein sequence ID" value="GIY11243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="40" mass="4663" checksum="7F30980E3F8FA3F7" modified="2024-11-27" version="1" fragment="single">MHSSEDQSSTSTGEQKRIASKYNFIKAKKYWTGSFQQEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNP1</accession>
    <name>A0AAV4QNP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_181881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006528">
        <property type="protein sequence ID" value="GIY10454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8477" checksum="0FBD7A7FA08FCD82" modified="2024-11-27" version="1">MKSIRRNGNAVLRRTVVVFEQSSSESSSIEDRCCSFLPNSYSIHPFPYPPPPLFEPFCQKKEGGDGGWAVVLVENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRA7</accession>
    <name>A0AAV4QRA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_141921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006546">
        <property type="protein sequence ID" value="GIY10631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="8997" checksum="747B233329D70F9E" modified="2024-11-27" version="1">MPKRGGGQHKSSAFINFSGMTSLFLTDEPTTPFSSAARRTTASTVSPASPSPRVVTQEASVVKRRRSFRHRRRSFGSALIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUC4</accession>
    <name>A0AAV4QUC4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ImpL2</name>
        <name evidence="3" type="ORF">CEXT_686661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006888">
        <property type="protein sequence ID" value="GIY13065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="78"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="190"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY13065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="275" mass="31319" checksum="FB78178662878FE3" modified="2024-11-27" version="1">MRRWYIRANSLLHQSLERLKADTTPEQRKAVANCRQVPPDCLVIIFSLSRHVDHSTRRTSSRRHEDVREGDESSWLFPRANLRLHSKPPKVLHTKEGGSEILECQAGGSPRPHIYWLKNGKQLTKDDLADELELNDDNRPKLNMGSTSSRLYLDCLTAGDEAEYTCIAENSHLRESTTTRVTVSSSDDRSCHDKNNSVKHLELAEGEPKPTIKWLDPFNNEIDPERKLRFEIMSNGDLIISNLKWKDMGNYVCVAENTHGSARAEAFVYPAAPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUQ2</accession>
    <name>A0AAV4QUQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_813291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006709">
        <property type="protein sequence ID" value="GIY11852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005246">
        <property type="term" value="F:calcium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051641">
        <property type="entry name" value="RGK_GTP-binding_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45775">
        <property type="entry name" value="RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45775:SF6">
        <property type="entry name" value="RAD, GEM_KIR FAMILY MEMBER 2, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11248" checksum="AFE542BCF5976F73" modified="2024-11-27" version="1">MKYFQEEAKSVACSYECKFIETSAAINHQVDELLVGIVTQIRLKAQQQLDMATFTTNSTSKGGRSLQKRMSLGGSGKKARGILNKLLGKGKIKSQSCGNLHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUT0</accession>
    <name>A0AAV4QUT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_701441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006880">
        <property type="protein sequence ID" value="GIY12997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12537" checksum="C54A805C7E79AD13" modified="2024-11-27" version="1">MNLSAVGKKMKMIVKEKSSYFTPRDLFSLRMQASKRFETEFSNHLLINSRNLDDDEEISQALKIVKEFFSNVENPGKSFKNCFIIWQDLCVENVICDIAYEKTRCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8I0</accession>
    <name>A0AAV4R8I0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_804791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007491">
        <property type="protein sequence ID" value="GIY17281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8I0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="27745" checksum="5ADC08097D7BFC19" modified="2024-11-27" version="1">MKTLDDIYMICEHYRLNGLTEEAVVFFRPLLFSGDGEHDGCNLPPDVSAGDQMDIDNKGNGNYQVHSEVPENGTVFEGTRHKSPSGCELTDFQLREWYKTLQMDIVNNERLVTVCLNTSNEPLHETITKQPLPTWQLVLTCCKDSNEILKLNKLLYLRVKVEKFDERPLATHCFHCNYCHHSSSNSGYKSRCLKCVGEHYLYGCTPKTEKINQPTCISCGATPQLAVSEGAQDSLSPVLTLLRVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCG2</accession>
    <name>A0AAV4RCG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_239705_1</name>
        <name evidence="2" type="ORF">CEXT_642691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007723">
        <property type="protein sequence ID" value="GIY19165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="26172" checksum="5F8585F48615CAE4" modified="2024-11-27" version="1">MILPRNNHSERNIFSSNCRINLYRLAERLHPSAPPLFDSSPSPSAREGRAGKGGTQEEKVLDDSLEKEGKKRSKYLLTSELIKWQALTPSITKSSSIKKESANPFSNFFSTEEKEFLLRQLVADLVFGGSSPSTVLSTGRRFPATLHVGLAWDADPSTLAEVHPRAIRGRNPPGHLGHVDGPVAAPLGHCKERHRGGGGHDTFSPTQAIAAKTGISRSQFSLPYDAEVCYSSLLTQCVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RD49</accession>
    <name>A0AAV4RD49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP synthase subunit gamma, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ATPsyngamma</name>
        <name evidence="9" type="ORF">CEXT_413961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007735">
        <property type="protein sequence ID" value="GIY19267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RD49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF22">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY19267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12915" checksum="CBD3C8928FD4DCFF" modified="2024-11-27" version="1">MAVYSDYGKKPPTFEDATTVADYVINCGFEFERGIILYNRFKSVVSYDTTEMPVFSAEAITNAEKISIYDSLDADVIKCYQEYSLASLIFYAMKENACSEQSSRMTAMDGASKNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFP1</accession>
    <name>A0AAV4RFP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_797211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007695">
        <property type="protein sequence ID" value="GIY18927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14774" checksum="ECF7C5EEE07A8A97" modified="2024-11-27" version="1">MEGGPDKEMQWRLQLRAEVQVAQAAGIRSRRRLQGHLHGLVPLPILLRLQVSQPHQAVTPISKPQIIFCSIERDKEKKKRLPHLSGQVIKCYRFLVLVTLAKNGHLSQVLDLATTMWLNQAEERLKIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKP7</accession>
    <name>A0AAV4RKP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_249011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008004">
        <property type="protein sequence ID" value="GIY21336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8246" checksum="94C4B2569D074FA2" modified="2024-11-27" version="1">MGKRRMGVFHGYQIPKNGCIPWVSNSFVCGLEVFAARVQKDSLSKLLLESIAVNVFGQKMLVTAYLDKRRVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSU6</accession>
    <name>A0AAV4RSU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD repeat-containing protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Wdr19</name>
        <name evidence="2" type="ORF">CEXT_426241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008266">
        <property type="protein sequence ID" value="GIY23360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040379">
        <property type="entry name" value="WDR19/dyf-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039468">
        <property type="entry name" value="WDR19_WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920">
        <property type="entry name" value="OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920:SF0">
        <property type="entry name" value="WD REPEAT DOMAIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15911">
        <property type="entry name" value="Beta-prop_WDR19_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WDR19 WD40 repeat" evidence="1">
        <location>
            <begin position="52"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20531" checksum="A61E051B5A5CFEFC" modified="2024-11-27" version="1">MLHMITVDDEQFIDGIQWSDDGQLLALAGGEGNLHVYLTKLPVLGSVCGQKLAHLSSLYEVSIYSARKKDNVTKLKIDVEPKFIALGPYHLAVGMNNRAWFFILSVIQVEYLSTVRSLYLNSDYASALIDGKIQLHMIDEPNMPCMERESRIFPDPDQRNTVITCHALTNDFLIFGTDVKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUA1</accession>
    <name>A0AAV4RUA1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_147981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008548">
        <property type="protein sequence ID" value="GIY25483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19912" checksum="31B98FCF09669126" modified="2024-11-27" version="1">MLTTRLNYFLKLMASWKSDVLGVHWINLESRYRQSKVGLPQGSVSSPSLFNRYVNDLIKSLTKTGNFQVCMFTDDSVIWTKGRQQSELQKTAKHAASEFELYLDNINTSKITPSTSVTDSLPLNHLWLMRIKNINSMGVIWGVDGSFENAMLIRWELAPFNALLDFLTAFVKTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUT8</accession>
    <name>A0AAV4RUT8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_294981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008329">
        <property type="protein sequence ID" value="GIY23892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16384" checksum="8A364D5249B4FD48" modified="2024-11-27" version="1">MDGSVDALVPRGAPSSNPHNEGILSHLPQKYQFNLGGTSERTSSRGLHLDLHPGPDLGVLVVVNRRSLKSDARKTTRKVAEGLDVDRSTVVRHLHRGGNQKSSTNHELEQLLNPVGTVTLETYCQDIGKMHQKTVTFMASIGLSKTTHSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY39</accession>
    <name>A0AAV4RY39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_452941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008481">
        <property type="protein sequence ID" value="GIY25032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16538" checksum="351167A712FF039F" modified="2024-11-27" version="1" fragment="single">EVSVAGHSPLRIQGRHALRAQTVDILFLDTQGHQQFATMHSEVGTAENRPHLISSEWNAYLLSRIIKGKTKQKSEKDIILIITFSLTPLLIEIRCIAKLLPRIIMPSVETLSIRDCMYKSGPQYHSPLIPANATARHTGERIVTPMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9G1</accession>
    <name>A0AAV4S9G1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">B9 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">b9d2</name>
        <name evidence="8" type="ORF">CEXT_652201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the B9D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009279">
        <property type="protein sequence ID" value="GIY30810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF2">
        <property type="entry name" value="B9 DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY30810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20490" checksum="DCA924B32E795AC3" modified="2024-11-27" version="1">MCEVHVIGQITGASEFKENNLFCKWGLHAGGNWKVIEGLKEGQTQIDNPLDGEMNYWCHPIDIHYATKGIQGWPRFYFQVWHQDDYGRDQFCSYGFCHLPTSSGYHECQCLTWKPKSSICDRFYEYFLGGGLQLKNPENIYHGLDRFRFQTVAMGIIHLELYVISKNFNKYGIVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJN7</accession>
    <name>A0AAV4SJN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009639">
        <property type="protein sequence ID" value="GIY33421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7772" checksum="15A9480388C50E18" modified="2024-11-27" version="1" fragment="single">MKAIQGIRELYLSGEKLSAGSKQRKTLWKKLKLTNLMPNFHLTPIYKPVLLLKTLALTFIGNLPLLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SK36</accession>
    <name>A0AAV4SK36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_514861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009656">
        <property type="protein sequence ID" value="GIY33556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SK36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19739" checksum="A8D16D8C3DFDE1BA" modified="2024-11-27" version="1">MIGLTSLLQSSSPHLHYHEFELFKDIDTPSSVKGDLWGVEKRESPMSRGKLFHCKCSKKKDSREQRSESRHHKTPFITIDIHITKKHDGKLFHCKCSRKDSRGQRSESRHHKTPSITIDIHITMKHDGEEEEKKAATSPTGESIFTRGDITQEVFSAHDVCKASYKINNSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNA2</accession>
    <name>A0AAV4SNA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_541221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009595">
        <property type="protein sequence ID" value="GIY33138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11033" checksum="1A0F0A037F53A23F" modified="2024-11-27" version="1">MSYGQRKVVDSVCSRMDWGPETVVNENRCHARIWILGYRGHRWGKKWGRLKESIKRQAMGDKERHQVNFYEEEISVILVGGFHNSKRKLASGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQ42</accession>
    <name>A0AAV4SQ42_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_654021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009854">
        <property type="protein sequence ID" value="GIY35079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQ42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10101" checksum="28E2C6A4A7BEE47A" modified="2024-11-27" version="1">MEKIIPNPYNYFSKAQIHSSLRENRLQRNRTFLLDGMATRSGTSSFSQREIPGGASIFLVRMGRGGVPSTNGEPPPRLEYFYQTIFSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSQ6</accession>
    <name>A0AAV4SSQ6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_411021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009925">
        <property type="protein sequence ID" value="GIY35525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048998">
        <property type="entry name" value="STPR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21107">
        <property type="entry name" value="STPRs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STPR" evidence="2">
        <location>
            <begin position="95"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY35525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="360" mass="43206" checksum="F4DE767E6F835A4F" modified="2024-11-27" version="1">MPRKEVARPCKKLLSKEPQKRHEEIRSENSEDRQARLETIGERRSKETEHHFQLSLERNDSCQTRRRETPEQRERRRQYMREWHQRVKSTETPEERERRLKRQRVVNKRARETETPEQRERRLELMRARYKSVKETETREERERRLEHHRAVNKRARETETPEQRQRRLERDRFLKLQARQRETPEQRESRLECMRLRNKRVRETETLEQRMVRLEKRRNIRAQKKNGKKNSNDVTPVEPPNVIKEEPIEFDLEPSTSAGIVIQNAKKDNEDVIRVEPAVFIKQEPIEFDPQPSASADIVIKDEFVVCSEDYTGSSSDVPSSSEHNSHVTLSVACLGSSQNRDNKWPINPVWLVNPVHNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SX30</accession>
    <name>A0AAV4SX30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_80001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010390">
        <property type="protein sequence ID" value="GIY39023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SX30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11610" checksum="64D539504AB88D1A" modified="2024-11-27" version="1">MNEHLAFLRKRLHYAENDLKSVIASFDVGLPTATDVTNAQKRTDDARRNWNCTRKGNVQSRTIRKPYVYQLPADRTSRFLEGFPKFPQPRQQPIGRSPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T6C2</accession>
    <name>A0AAV4T6C2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_472601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010465">
        <property type="protein sequence ID" value="GIY39453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T6C2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="27559" checksum="6CB43EDA04C974AE" modified="2024-11-27" version="1">MKAFCQETKQNKSKSNQQPNLSKQQQKSIGVKTASLIWTDWCSEDEWCPFSGQFRDRTTPSSFPFPLNAHRVSLDTFVREPLSPSGISSLQDSLLWREMESMMSPASRFVDHDSLLSGGVVDIRLHLFVVEMQTSSKSLLISIQQKPSRIPPPFIFQVHEAFLSRDKTKQKGKHQATQAIEAATEDHRWIKTASLIWTDRCSEDEWCPFSVQFRDRTTPSSFPFPLNAHRVSLDTFVRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBF4</accession>
    <name>A0AAV4TBF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_315871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010894">
        <property type="protein sequence ID" value="GIY42786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043652162" evidence="1">
        <location>
            <begin position="25"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13533" checksum="D90CD7AB7637B6F7" modified="2024-11-27" version="1">MAWIYGDILMLLNWLWECRIDSLAVNDLTPIFLPNHELAGDMQGAWFVCLHQTPTDGNTSAHRTMCLSHTNLLPCSKQYWTLWALGSLKKGKTPQLGCERKKANVELAWRQLRHQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKX2</accession>
    <name>A0AAV4TKX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_771431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011370">
        <property type="protein sequence ID" value="GIY46131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10930" checksum="3E1EA0E4EAB67EFA" modified="2024-11-27" version="1">MPISESVKPLMNYLASSQFLNHSGKRRGRTATLLSTSFRIAFHCAANKSSFRIWYADQLKGKASGFEIDGLAGVGVGYLVEDKGWDSVLSECRFCFAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQ93</accession>
    <name>A0AAV4TQ93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_492261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011688">
        <property type="protein sequence ID" value="GIY48229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQ93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17060" checksum="ABC87C43F355C86C" modified="2024-11-27" version="1">MFPKYHEKEGPDALRNKKGKKIRVSGVLGICFHSINQQSRCNAISRFFFPLSKTAKSSDSNVTPFPLDKPNNTQQHSGPSTSISHDGSLTFVTLLLCVGHWDSIWEERVAQLFLHLEHRLQIAAFNANQEWGIPDRKGGNLDKQSSSCKLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVU9</accession>
    <name>A0AAV4TVU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Troponin I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_508272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the troponin I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011856">
        <property type="protein sequence ID" value="GIY49601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005861">
        <property type="term" value="C:troponin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006936">
        <property type="term" value="P:muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001978">
        <property type="entry name" value="Troponin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050875">
        <property type="entry name" value="Troponin_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038077">
        <property type="entry name" value="Troponin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13738">
        <property type="entry name" value="TROPONIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13738:SF1">
        <property type="entry name" value="TROPONIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00992">
        <property type="entry name" value="Troponin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90250">
        <property type="entry name" value="Troponin coil-coiled subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY49601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="271" mass="31605" checksum="95A803B486AFF267" modified="2024-11-27" version="1">MERPNEQYIGFYCEKILYRLQRLTKIPEIPEFLRCGTRVSHSSQLLGFLNLLWQVPLDLGPINDKSWPSKNEKRVQEEKDRKKAEVRARLEAAAQAKKGGKKGFMTPARKKKLKRKGKKAAEELKKEQERKAEERRKTINERCGPSKNLDGINEAELMQICKELHDRIAKLESDKYDMEYDSRHKEYKINELNMQVNDLRGKFIKPPLKKVSRFEYGKFEKLMRAAKKADHSFRANLKSVGPSTKFKLDEDVKEAKPDWALGAKKGDNPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U397</accession>
    <name>A0AAV4U397_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_417101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012216">
        <property type="protein sequence ID" value="GIY52241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U397"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09276">
        <property type="entry name" value="Rnase_HI_RT_non_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="23853" checksum="D04FBD4F7559F7BE" modified="2024-11-27" version="1">MLHFYQLKYLHKSITVQNTIISAAELEDPPTIEPPWEKKYEWKYHQESDSGCCIFTDGSKMGNRVGCAMKLYFLKNKIQDFTTQDLVIRAQSFPFFISFIPPWDKKSITWNVFNENITGTLIFTDGSRMDNKVGGAFVVCKNNIETSHKIFRLSDHPTLFTAELMAVNAAVDYCITNHLQASSIITDSISVLLALVNVNNTNSEISIIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAG7</accession>
    <name>A0AAV4UAG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_468931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012554">
        <property type="protein sequence ID" value="GIY54775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8387" checksum="438C39B6D65D4EF5" modified="2024-11-27" version="1">MCCTIMYEMRTLSEANQLNNSTVQYSLPFSHEALNTSRTPEAIHLCISPETAKNEAGKFHSEIAYQLPEHICKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDZ9</accession>
    <name>A0AAV4UDZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_85071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012721">
        <property type="protein sequence ID" value="GIY56050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="19869" checksum="743236111B90643C" modified="2024-11-27" version="1">MENTGGKFTFQSCLNVNSTALTLKQGLSTANELSTRAIQLYHVLYGPFLKRVLATPVNTGAPAENRRQLGAFVAPRRVPSYSTGGGRVSHLLRFNPVRNRISSFATYCFSKYLEPKTFPVIRRRRSCTTGKSPDPFKCRWGLGGLGWNEAYRDSVPRPSRSDSSLPNSNVIAISPEEGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UED0</accession>
    <name>A0AAV4UED0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_391731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012736">
        <property type="protein sequence ID" value="GIY56178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UED0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16362" checksum="1D871AB0B0FD7A48" modified="2024-11-27" version="1">MKHRLTSIMIGAIRSPDVISRKFFCGTISIIRSGVNTFDIQLVVAAIIVIAPCRISLQYYTDSTYTAWKKKYTRKGFLRKCYERKLTKLSKKALGGFEEEIVEGLTSQQRRKEKTSDLQTQYLKSILGYLEKVFQLEENHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJQ6</accession>
    <name>A0AAV4UJQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_478401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013001">
        <property type="protein sequence ID" value="GIY58008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="650"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="692"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="801"/>
            <end position="819"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="831"/>
            <end position="852"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="896"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="925"/>
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        <location>
            <begin position="1075"/>
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    </feature>
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        <location>
            <begin position="1100"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1141"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1208" mass="139707" checksum="125DC3590774D1EC" modified="2024-11-27" version="1" fragment="single">MYDTFPQFCYISAVPIYYISAVLLHLCCSNLLHFRSPTHLCCSNLLHFRSPTTSLFFQFTTFPQSYYISAVPIYYISAVLLHLCCSNLLHFLSSTTSLLFQFTTFPQSYYISAVPLTTFRQSYYILLFHLLHFRSPTTPCFSTYYISAVLLHLCCSTYYIFRSSTTSLLFHLLHFRSPTTFCCSTYYISAVLLHLCFSTLLHFRSPTTFCCSTYYISAVLLHLLAVPLNYISAVLLHLCCSNLLHFRSPTTSLLLFHLLHFRSPYYILLPEFTTFPQSYWHLCCSNLLHFRSPTTSLLFHFTTFPQSYYISVVPLTTFPQSYYILLFQFLLHFRSPTTSLLFHLLHFRSPTTSLLFQFLLHFPQSPLHFCFSNLLHFRSPTTLLLFHLHFRSPYYILLFHFTTFPQSYYILLFQLTTFRSPTTFLAFPIYYISAVLTTSLLFHLLHFRSLLHLLSCSTYYISAVLLHLCCSKFTTFPQFYYISAVPLTTFPQSYYILLFHLLHFRSPTTSLLFPIYYISAVLLHSAVPTSTTFPQSYYISAVPLTTFPQSYYISAVPLTTFPRSPTTSLAVPLTTFPQSYYILLFHLLHFRSPTTSLLFPIYYICAVLLHLCCSNLLHFRSSTTFLLFQFTDIQFYYILLFQFTTFPQSYYISAVPIYYISAVLLTSLAFPLTTFPQSYYISAVPILLHFRILLHLCCSTYYISAVLLHLLLFHLLHFRSPTTSLLFHLLHFRSPTTSLLFHFTSHFRSPTTSLLFHLLHFRCPTTSLGAFPLTTFPQSYYIPCCSTLHFRQSYYISAVPLYYISAVLLHLCCSNLLHFRSSTTSLCCSTLHFRSPTTFCCSTYYISAVLLHSASSNFHYYISAVLLHSAFRSTLLHFRSSTTSLLFQLLTFPQSYYISAVPIYYISAVLLHLCCSTLTTFPQSYYISAVPLTATFPQFYYTLLFQFTTFPQSYHISAVPLTTFRSSTTSPCCSNFLHFRSPTLHLCCSNLLHFRSPTHLCCSTYYISAVLIHLCFSNLLHFRSPTTFCCSNLLHFRSPTHILLFHLLHFRSPTTFCCSTYYISAKSYYISAVPIYYISAVLLHLCCSNLLHFRSPTTSLLFHLYYISAVLLHLCCSNLLHFRSSTTSLLFHLLLFRSPTISAVPIYYISAVLLHLCCSTYYISRSPTTFCCSNLLHFRSSTTFSAVPIFHISAVLLHSAVPIYYISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UM36</accession>
    <name>A0AAV4UM36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_479101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013073">
        <property type="protein sequence ID" value="GIY58530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UM36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16463" checksum="EFD9D323E4A301EE" modified="2024-11-27" version="1">MTDSVEKKEFNILSLIYPDVSKDYSTPLKFPAPFPAATKTLRTRNTKINFQTTLRHSSLLTPSLYNSLKLYDKLKTHIFFHDHYTRRTFFPPRKIFRNDSMVTAFGAPHLCCRKFTPFPPPFIGGLNRSQPSLNSDLRGHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQK8</accession>
    <name>A0AAV4UQK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_699_1</name>
        <name evidence="3" type="ORF">CEXT_254301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013284">
        <property type="protein sequence ID" value="GIY60156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY60156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="25334" checksum="6544AC1802DF4D51" modified="2024-11-27" version="1">MTKYVSYVIIHHNFEGPLIIMIFTMTCCLVLSVIIVLMLLIILVFVVYVVVVRAKRHSEDLSSPNLFGTVGASRAVSNSYKEATSNRRTLSNQFPVFDERHANLNPSIQNIPMSTFNPETDERQADSSNSSPGGLREFLFPPRHDGEIIYKAPPSVVAFAGQVFSTSRAGYRANSVTEPKMPRPGAAARHSDPVNATLEWDYFESRRYSTSEVSNEPGHHGINICWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4USB0</accession>
    <name>A0AAV4USB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_155381</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013356">
        <property type="protein sequence ID" value="GIY60677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4USB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19941">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050780">
        <property type="entry name" value="Mucin_vWF_Thrombospondin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036084">
        <property type="entry name" value="Ser_inhib-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002919">
        <property type="entry name" value="TIL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014853">
        <property type="entry name" value="VWF/SSPO/ZAN-like_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11339">
        <property type="entry name" value="EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11339:SF386">
        <property type="entry name" value="HEMOLECTIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08742">
        <property type="entry name" value="C8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01826">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23244">
        <property type="entry name" value="VWF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00832">
        <property type="entry name" value="C8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00216">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57603">
        <property type="entry name" value="FnI-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57567">
        <property type="entry name" value="Serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="Sushi" evidence="4">
        <location>
            <begin position="52"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="VWFD" evidence="5">
        <location>
            <begin position="209"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="VWFD" evidence="5">
        <location>
            <begin position="563"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY60677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="653" mass="72204" checksum="FDD4919366BF63D8" modified="2024-11-27" version="1">MANLTFSSQKRPCLLISLGRQCGAVRRVFTAQHAEDYDDAAHMSMSDFEHVKICVDPPPPENGDMECFKHKTKQNRYVCKAKCEPGFEFTSGKPVEKLTCSLKSGKWSKTVFQNVYKSHCVIQTRVCTYQETGYATIPSQIPGAFLNCPQGSRYESQPAELYVCSLDGTWSPSFAPKCIPINVIEPPASSSFYAISSGEVVQSTRPSSSVCSTWSASHYRTFDGGVYSFTSPCSYLFAKDCEQNTFAIHIHNGEYCATESHCSTAITIYIGAEMYVLTSGAEGPYILNGEEMHPVPTSVKGLLFQMLSNYVTVTSPLGFKLKWNLQNTILLEVSSPLKNRTCGLCGKFDGSVQNDFGTSDGSITDSVEGFVNSWAMEHIGGKAIVKDSCAENKNRAQEAEQNCQIIYSDKFSSCHHLVNPKPYFETCRMDYCGCEMWGSCHCSSLTEYFRECVRLGGEIPGGWRSDELCPLSCPGGMVYTDCGTSCPITCKGTVYACEDDRCIDGCHCPEGTALHDGRCVDIFSCPCLHNEKEYQSGERIIQDCNACECTAGKWQCTEETCQARCSSTGDPHYTTFDGYSYEFLGSCPYYLVYNEDFKVIQENGPCTSELNVEPATDTMFCTHSVTVEYKGNSLVLEPGIKVNYFTILKGPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UV19</accession>
    <name>A0AAV4UV19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_633901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013485">
        <property type="protein sequence ID" value="GIY61576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UV19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="18721" checksum="F1A8FAA68B0A2DAB" modified="2024-11-27" version="1">MRAIRACYPNHEKKCRIVVLSIADMGTITPQPRSIFLKCMRNGCETVEQTPSKCDGKLVTDYCEQFGQAVAHCTLGAFNFPENDFTEPIQSAKPPLPKCNSKLVTDYCEKFVQAVAHCTPCQLLSSFGENKAGRNVLSHLMSSKEFNSVGWSGLIEVFKHINDSAEIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVA5</accession>
    <name>A0AAV4UVA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_418281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013453">
        <property type="protein sequence ID" value="GIY61339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="22091" checksum="CB1C835A9071FD12" modified="2024-11-27" version="1">MSVEESSNADQPLPNSEHLNTDPTEHVLNFVEFSVKFHKNRVLPVLPKVLTFLANVRDSLEEELLENGLLNSTAWNCNERDIATENDETDNENAIEKSNESKLLEISKESVNDFSEPEDKKGDNDATLFEHGEKVLKIDEKTSEITDPTESELSSNILSESVCDTTQNFKNSNNKSVVRESIDDELNQPPLKKICI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY47</accession>
    <name>A0AAV4UY47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_557661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013649">
        <property type="protein sequence ID" value="GIY62663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="11496" checksum="C4191B98801861A4" modified="2024-11-27" version="1">MRTLKQLTIDNYFPRTSSTFRENFYMDDYYVERKFWRMEKSCSINLLQFCRKWEWSYICGVLTIQNFCQTRTKTTVSRIQMRPKLWKYLGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7T1</accession>
    <name>A0AAV4V7T1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014058">
        <property type="protein sequence ID" value="GIY65984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7T1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8714" checksum="8C4FD08667149918" modified="2024-11-27" version="1">MIHVPVHFEYFHCTCISWATAVTLALPYANIIDKSETAVDDDDGYLIKCQDIGRALNLTNHSRYGKKNVRGNVGVFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V870</accession>
    <name>A0AAV4V870_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_267041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014106">
        <property type="protein sequence ID" value="GIY66296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V870"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9591" checksum="9FED38236D1CB626" modified="2024-11-27" version="1">MVPYRKTKSSGTGIPDPPVPRGDVQGSVRLDTYLAAGRTIQESHSCDSIFPYLAISGRIPSWLIYTNFSRKEKTRKNGGRIPGVALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VID3</accession>
    <name>A0AAV4VID3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_91531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014634">
        <property type="protein sequence ID" value="GIY70176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VID3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12009" checksum="29A616192753C28C" modified="2024-11-27" version="1">MSDALGVGILCFNGKPFYRRWLYSRVFTLESFEQGDANSRSIAQANKLGIERLLRGSPIIKAAGLPKLCIRLLDVRKRDSMHYSCAMTEMEFAQGLGCVIRERYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLK0</accession>
    <name>A0AAV4VLK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_316461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014738">
        <property type="protein sequence ID" value="GIY70973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10603" checksum="C8B61D6C13C41CDB" modified="2024-11-27" version="1">MPPSSREIKGYIKKQCAIASRVTEEQWPSTGRRLDRNFGQQPCFVGLFLASRVSLVNWGIEKARFFFSFVLSCYFCWRERILPKNAYIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZB2</accession>
    <name>A0AAV4VZB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_217735_1</name>
        <name evidence="1" type="ORF">CEXT_493171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015389">
        <property type="protein sequence ID" value="GIY75787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15158" checksum="DD92A1324FB171BE" modified="2024-11-27" version="1">MKIVIFENSKTAEKKSGTMSIVSVAILFTKNSPHPLMLHRSTYENRYPETCEFLNNSITDDGIVGGHQNTERAYNTLLECIHIFKEAGMILHKQQTNSKALQELWMKEDYVLKDSSEIFRSTNVNFKVLRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W621</accession>
    <name>A0AAV4W621_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_508751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015619">
        <property type="protein sequence ID" value="GIY77401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W621"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17317" checksum="C2BC44C32C221DF0" modified="2024-11-27" version="1">MPPPEFELEACGTKCQRAIQLASGCLNLVEESESYKCYPGMLSRSEFWLTGKYNSPLMLDACCYMYAVQDENESGSIEILKLAKGASLGRKTMSWGGKRQREFLRESTCTCGGEARSESTEGIFIPLVESEANFRGKPSAELHSHTIQSQNLPTGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVB8</accession>
    <name>A0AAV4WVB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_115764_1</name>
        <name evidence="2" type="ORF">CEXT_811541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016795">
        <property type="protein sequence ID" value="GIY86441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16456" checksum="3FFE5BBB6F54F9DC" modified="2024-11-27" version="1">MSSPKSNQLAMRTKSLRERFGSKRSYSENFKDPPVTATTSPSKEGCRTVRPSLPIIGIPGMPTDESKDPQKIYNPYAQPQNLLQQQQKRQTNVLSEHYNPFAVLPEETYCSALDINSQEGDPRFPWQRDAAVQCDLSPDPDGLRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1G6</accession>
    <name>A0AAV4X1G6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016955">
        <property type="protein sequence ID" value="GIY87588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1G6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9643" checksum="D37F0641F4833461" modified="2024-11-27" version="1">MAARFGNMQGSCCSYSMLALHNFLKLADDAMPPLKRRYCPPGYSDTLSRDGDTILGSWRQEECALKMVSLIGSNMHTKRILSNISAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X911</accession>
    <name>A0AAV4X911_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_274611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017319">
        <property type="protein sequence ID" value="GIY90451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X911"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11831" checksum="4A24C0BE7F710E04" modified="2024-11-27" version="1">MYLLSIKFIQFHYLFFLFFKICRHTPHPVRQLCFRALVIVFGSFHKLINVQSYENGPQTCCYDLSDAGCQLGTTSCRALQCHTTDTLQGVRSNGGQFFSLPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAF3</accession>
    <name>A0AAV4XAF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Centrosomal protein of 41 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cep41</name>
        <name evidence="13" type="ORF">CEXT_667221</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CEP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017430">
        <property type="protein sequence ID" value="GIY91577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051889">
        <property type="entry name" value="CEP41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44390">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 41 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44390:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 41 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rhodanese" evidence="12">
        <location>
            <begin position="151"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="300"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY91577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="364" mass="41543" checksum="C617936987633C60" modified="2024-11-27" version="1">MYSRHKSLNFGQYIPDDKVLNKKVPENPKYKHVRPAINTGKNVKSHIDELKEKQKKSYFYLGCNHKKDEVFYRVKLSSFIKLAISVAQEIFKQEERGDFSSRLEVENSSENHKEDKNILANVLIGIGEIDLRNERKKQPVSQPKIERKIPYLLLDVRDQEEFCRGHIKTAKHYPASMLSRSIGYEIEEMKHYKNNRPELIVLYDNDESIAPRVATTLVQRGYDNIYVLSGGLNLGYEIFPRALMASVTTRLPSKMSPSSSVQIKTSSEYFSQEDVENIQQYLEDCPQKSYPVGNSKSCTSYSKSDKSSSFVSKQSGSSMAYAGKCGSVTFRKDSASSSRSFETARMRAASTDARFKTAKKAPWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB93</accession>
    <name>A0AAV4XB93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000063">
        <property type="protein sequence ID" value="GIY91877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="207" mass="24013" checksum="FC8ECB9BC3E46378" modified="2024-11-27" version="1">MDSTLLVGVDKLRHIRTLAAAQEYLPIVFEWDSRIRFGVLEACRNPVSFRLYAENSYIKSVSQKVLPLDSRISGPSIALKLREVSDNFICKQNPVARIARIGVQLFEGVLTVNQVFQLQYQPTHQGFQLQYQKPTKVFNFNTNQPRFSTSIPTNQGFQLQYQPTKFYNFSTKQRCFQLQYQPTKFFNFNTNQPSFSTSIPTEFQPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBM6</accession>
    <name>A0AAV4XBM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mechanosensory protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mec-2</name>
        <name evidence="4" type="ORF">CEXT_192461</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000004">
        <property type="protein sequence ID" value="GIY91349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="50"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY91349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="17971" checksum="8292BA1F59D5D9BA" modified="2024-11-27" version="1">MTFNVPSQEILIKESVTLQVDAVIYYRVFNAIASVVNKDKNSTHFAGFFLNETTQEWGIKVEKVEIKDVRLPESLQKAMAAEAEATRASNAKVITANGEKKGFKGVKKEAAEIISECPVALQLRHFPVVSSLKTEQQQQQQQGEQEEKKLRKFSIPFGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCF1</accession>
    <name>A0AAV4XCF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_147823_1</name>
        <name evidence="3" type="ORF">CEXT_109411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000095">
        <property type="protein sequence ID" value="GIY92108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY92108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="21864" checksum="E8E18D3BED47277C" modified="2024-11-27" version="1">MNFLYKLQDLKNELYYPRLRFDNFWFKSPVDNYTRKNESIRKIDHTLTWPAWSTKKEIYNKRNRKNHKQTDPFEDILGLDSKLHELSDRKYIHEHEGFFFPVHVPSSHHHEKEDHILIPLLLIILIPLLLFAIIIPLNANLLSTLFLIMQNNSATTTAAQLATGRRKKRSLHTSQHPIVEEKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDG6</accession>
    <name>A0AAV4XDG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_154817_1</name>
        <name evidence="2" type="ORF">CEXT_525101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000121">
        <property type="protein sequence ID" value="GIY92270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="401" mass="42663" checksum="8D8C0A2537455D5F" modified="2024-11-27" version="1">MTFVILIRSEKQLFGDPEGVNTSVPAVASCPSIVKLEQRVSVNDTRNPDAACDEGLVSDSEVGPGAYVTAYVSCVTSSSSSTSTGRPGHFRSASDNVTSATSLLIPEDRMKKTSSAERLWSTVSSRLNGTEKRKRRKGIGSKQQPDGTTVQASPVKSGSGRSLTYPPQRKSSTSEEEQEYTSVDSNGLKSLKLLTAGLMESERDAVRLLSDLSLADSHLCPSEGTVDETYQDVVDSVMHSSSETKYLSVDENGNGKTQKKKHHSDPGGEACSPTSGEGFMGDTIGSARSEPKLGGNDNLTSISSSSTSSDTSSRATQTSSQHSDLPQLNQLKLVIEEHAPKSDKKNRHNRAASSGSLTSGAYPNSRFLFPDSDTSSQRLAIENNQASKSPQEQRGGILSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFP4</accession>
    <name>A0AAV4XFP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_51538_1</name>
        <name evidence="2" type="ORF">CEXT_51771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017704">
        <property type="protein sequence ID" value="GIY93776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1945"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2467"/>
            <end position="2692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
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        <location>
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</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
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            <taxon>Arthropoda</taxon>
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            <taxon>Entelegynae</taxon>
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            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
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        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Arthropoda</taxon>
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            <taxon>Entelegynae</taxon>
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            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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    <name>A0AAV4XSY5_CAEEX</name>
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        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
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        </alternativeName>
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        <name evidence="10" type="primary">Rps2</name>
        <name evidence="10" type="ORF">CEXT_263151</name>
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        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000721">
        <property type="protein sequence ID" value="GIY96964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000133">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000004">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="112"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY96964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="303" mass="33007" checksum="67F7E08453CCFAE7" modified="2024-11-27" version="1">MKSIRVYITCIQFINECNSKEDIMADAAPPAGGRGGFRGGFGGGGRGGRGRGRGRGRGRGRGRGKEEKEWVPVTKLGRLVKDGKIKELEHIYLLSYPIKECEIIDFFLGSDLKDDVMKIMPVQKQTRAGQRTRFKAIVAMGDQKGHVGLGVKCSKEVATAIRGAIMLAKLSIVPVRRGYWGNKIGSPHTVPCKVTGKCGSVVMRLIPAPRGTGIVSAPVPKKLLTMAGIEDCYTSARGSTATLGNFAKATYLAIQKTYSYLTPDLWKEQLLTKSPYQEYSDYLMLNHKPIGAATQQRQEQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX51</accession>
    <name>A0AAV4XX51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018352">
        <property type="protein sequence ID" value="GIY98873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8028" checksum="BB3B98D6FA4776A5" modified="2024-11-27" version="1">MEETTLSTRLEEAIKWMLLAISSDSCEEPIIANTSSSSNLQSPSIQKIRPSYPILNVIDTYQGTRIMPRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX77</accession>
    <name>A0AAV4XX77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_572971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000940">
        <property type="protein sequence ID" value="GIY98594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="18171" checksum="4D30B754DFBB36D0" modified="2024-11-27" version="1">MKHENNEVIDSFSSVIVLLIASFGNCDRSYRVIEKIRNNGKRNRPEEQARQSWPVKRRNSTTALIPGESERFDCSPRVLGISPKSSSSRTMHGRNAKSLQASECCRKLFQLDESYAKSNKEHVSKTKDKIPSSEERRREEEDEEEEEDENESSSFGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXI2</accession>
    <name>A0AAV4XXI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_161681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001089">
        <property type="protein sequence ID" value="GIY99846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12277" checksum="057E391CF24C2EA3" modified="2024-11-27" version="1">MPHISQQKGGNISYIFLIAARGVDLSSRCRYPYNPMMRNEEEPISYIIVVVLAKPWPLGSPYAYHIYPTESRAHDLLYKGGHQFHVCILHTNPLMENERRTCFLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0S4</accession>
    <name>A0AAV4Y0S4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_501811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018582">
        <property type="protein sequence ID" value="GIZ00738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13756" checksum="95ACE71726059C10" modified="2024-11-27" version="1">MTELEEHSSKTKETYYKTFRLSDSATVYMVELVAIEKTIDFAISHSFFSPVNIISDSDQCCLHLKISITWIHPFSTLKIKSYYTGRVRLFWIKAHVGHMGNERADALAKEATLPGYSTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1M7</accession>
    <name>A0AAV4Y1M7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_218181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001271">
        <property type="protein sequence ID" value="GIZ01258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="21551" checksum="8076991490CB8308" modified="2024-11-27" version="1">MRDITQKILKCLKRDAKKTLMGKSERGVHQDLQITNKLNTTMHLLPAQWEGEIHVADEKAARSPRDKPAQVEIDGTTTFLNAQIDRPRKEELIFCANFLHHTFRTQRSWWKRWTLIGLGERNKQFAGYLCRLEVFDWRSLVFGDGRSYGCCSSDFKVWYGWGRSGMSVSKRMVHSLRIIKFVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y333</accession>
    <name>A0AAV4Y333_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_392291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001333">
        <property type="protein sequence ID" value="GIZ01662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y333"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16645" checksum="E43550CCFA9B0D55" modified="2024-11-27" version="1">MLRKLLFLKKKIKRGKSEEEKHLTGLVIKLIEPKRRERERMKLRHIHECPSPRFFPQWERPKHNRCICPKRKREAVHSVVVPSSGRDLPRRSAGSRVWCRRHNGKWIHLSPISLRVSELMSHAQVCHRNRADERSQITAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5W3</accession>
    <name>A0AAV4Y5W3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_587421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001425">
        <property type="protein sequence ID" value="GIZ02269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5W3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11230" checksum="E5325EE2E26F3236" modified="2024-11-27" version="1">MEVNVINIGDFSNSSWKNATTFPVHPLPPHPFSRSIDKERGNRKLEMFCYLQFSFKCHRLNIPSELVRRELFRVARSCISAWMADWWDWDLVGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6A3</accession>
    <name>A0AAV4Y6A3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenosine 3'-phospho 5'-phosphosulfate transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLC35B2</name>
        <name evidence="9" type="ORF">CEXT_715911</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001457">
        <property type="protein sequence ID" value="GIZ02419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF13">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIZ02419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="223" mass="26019" checksum="922FDDB7B415D18B" modified="2024-11-27" version="1">MPIGWTESWIFRLAINLLGYATVAVPGALLVRYFKDRKYLDAPNNCIYKYINLFVHGEEDTRLPEIVGTVHPVKPKRSTTWKFFVLLICFVGLLGSYLVWGILQEKIMTQDYHNSNGEVGRFVDSQFLVFVNRVLAFIFASTYVSLSKQPKHIAPIYKYSYCSFSNIMSSWFQYEALKYVSFPTQVLAKASKIIPVMEQLYFYYQERHLVTLQPPQQHPELQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7S7</accession>
    <name>A0AAV4Y7S7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_592661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018898">
        <property type="protein sequence ID" value="GIZ03068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7S7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8416" checksum="6E5C99A6BE55EE21" modified="2024-11-27" version="1">MEARKAEAMGCQWPAEWKMSVSTAKTSQSKSPYGASLRECFAATTRAEPRCLGDSDCCFFIRRNESSCSCTSPQIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y857</accession>
    <name>A0AAV4Y857_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fatty acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FASN</name>
        <name evidence="5" type="ORF">CEXT_474161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018799">
        <property type="protein sequence ID" value="GIZ02332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y857"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF23">
        <property type="entry name" value="FATTY ACID SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="5"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ02332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="443" mass="48997" checksum="9703AD98265FAEB8" modified="2024-11-27" version="1">MEPKNRKLIHIYYSALNFRDVMLATEKLSIATTRHLGQGNAVLGLEFSGREDGTGKRICGFASARAMATSILAEPAHIFDVPDNWTLEEAATVPVVYATCYYALIMRAKLQPGESILIHSGTGGIGIAAITIALSLNCEVFTTVGNDEKKKYLRRKFPQIKEENIGCSRNVSFEAMIKERTNGKGVDVVLNSLADDKFTASIRCLGKSGRFVEIGKYDLALDREIGLKIFLENISFHAVFLDQLFDSSPKTAVILSEIMRLIRDGIKSGVVQPLDKTVFGRNSIEEAFRYMSKGIHVGKVLLKIRDEEQKKRIVPKCLALSAVPETQFYDTKVYIIVGGLGGFGMEGVNVQVYTLNAAVKSEAEKLLQMASSIGPVGGIFNSAVVLKDAFMDCQTAEDYQQSMRSQSYSFQEPGRVVEKTMPIHGLLCVLFVHQLWPGQRWSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8M8</accession>
    <name>A0AAV4Y8M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_76131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018938">
        <property type="protein sequence ID" value="GIZ03375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10106" checksum="9C4245B44CD48B0E" modified="2024-11-27" version="1">MTQHHLPPGGPSISNKQMPPLHGSRWSSDIAAVGRSLRLTTPMLMNCRSYITQLSGAFAGPFHPRECGFVEGWLDYFCFIKCIDFSLYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9F2</accession>
    <name>A0AAV4Y9F2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2236 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_83127_1</name>
        <name evidence="1" type="ORF">CEXT_783801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001674">
        <property type="protein sequence ID" value="GIZ03973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9F2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37159">
        <property type="entry name" value="GH11867P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37159:SF1">
        <property type="entry name" value="GH11867P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="16541" checksum="77234AE672C74C4C" modified="2024-11-27" version="1">MLGMEDRYNLCNGNLEETLAVCRDIMDGELRPSVQSARKESSTMSRGIIKAMNSFIVFLSWEAMARFWYEQMDLPCEFSMGIYESTGYWLMRFTFGWLLRFQIFHKFFNFLLRIAVKQALNSKEYYEGYLARYHNITNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCD9</accession>
    <name>A0AAV4YCD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_769821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019131">
        <property type="protein sequence ID" value="GIZ04740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11376" checksum="BA17DD614F251D63" modified="2024-11-27" version="1">MAPPRLEPDTCGTERQSASHSAIQAPLILLLQLSSRQNNRINLIYSIKMALNQNLEVNASQLAIRPPDLKKIKLRLSCLHSGVIPRNSAEVDWCAVPPTYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDC0</accession>
    <name>A0AAV4YDC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_171211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019188">
        <property type="protein sequence ID" value="GIZ05003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13668" checksum="E681B4DAE669A0FE" modified="2024-11-27" version="1">MRIPIILFVTPFLLDDLSPFPSRQEEKDLSLIQHSDLCLGKISGKKNEPSPIFFYPTKTNNKVPLQNENNLSPCPSRRKGLSRKRIQDKPGAGSDKPGKDPLFRKENRCTPATENAFLCKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M439</accession>
    <name>A0AAV4M439_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Down syndrome cell adhesion molecule-like protein 1 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Dscaml1</name>
        <name evidence="9" type="ORF">CEXT_657631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019328">
        <property type="protein sequence ID" value="GIX66620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M439"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20958">
        <property type="entry name" value="IgI_5_Dscam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000005">
        <property type="entry name" value="Neuronal cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="30"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="91"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="183"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX66620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="346" mass="37894" checksum="A4227BCDC28AF0F6" modified="2024-11-27" version="1">MKSSFGSLSQTAKKILVIFKNDLSVILPGELVWPQEEQLGDYVRTGRDSTEVVSYVNITSVRPEDGGLYECEASNDVGKATHSARVNVFGPPFVRSMSNLSVVAGETLRLQCPVGGHPIETIKWEKDGVRLPLNHRQKVFQNGTLLVRNVEKMSDSGPYKCSASNADGITAENTLHIKVIVKPLIEPFTFPKSLQTGQRFSVLCTITEGDPPIRIQWIKDSLQSFLASAHDGVRSVVVTPFSTTLVFESLAPEHRGNYTCVASNAAGTMSHTAPMNMLGLLGTADFRTSIKTFQGLRNQHVENSMTCVKGWGKKGGGEKRVGWGGFGLHYVIKQIVRTWNSQLSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4H5</accession>
    <name>A0AAV4M4H5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_45911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001870">
        <property type="protein sequence ID" value="GIX67351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4H5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="345" mass="38939" checksum="498CE7D8194A7428" modified="2024-11-27" version="1">MTEMVLEKGKVPKGIAISTFNNTKLLWLLSGQSCEDCTASLNIPDDGYISCNMTFRVIALKSLLGPEKRFIVQEKDFASCFDRRNTRHCSESCIKLPERLPPPESVPTKPETIPQKTLETAKVTPKIILQPATKTPETYKVAPMVTTHHVSKAPDTVKTALKKHFCDKAVEAHLDRVDLGTDLENDDNKSVLSYYSAESVTMPKKPELLNSSSNEDYYSIEHYSSVSHGSTLRGNTSLERKIFDIEKCVLDMFEQHSTELNDIKVELRELKKAVSGISSLQYGTSTNSSTNMQLLCHIQELQHSVHIVENKLDTMSIDINSRMKHQDRKLSMIRKELNTIISKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCG1</accession>
    <name>A0AAV4MCG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_422621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019643">
        <property type="protein sequence ID" value="GIX70043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9514" checksum="8F09194A8CB752B2" modified="2024-11-27" version="1">MRSLYWKDLNNDEMVPNARNSSKPDLVKVEKIRDPEVLGVKRVVQRRKVWEDKGANLSFLNVIYAATSFHKCLSMKELYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCW5</accession>
    <name>A0AAV4MCW5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SERCA</name>
        <name evidence="16" type="ORF">CEXT_459372</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01002120">
        <property type="protein sequence ID" value="GIX70193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000005">
        <property type="entry name" value="Calcium-transporting ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000065">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="15">
        <location>
            <begin position="186"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIX70193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="454" mass="49761" checksum="3B87D335321A6E15" modified="2024-11-27" version="1">MLDPPRKEVMDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFEEDEDTTGMSYSGREFDDLPVSEQRRAVQRSRLFSRVEPSHKSKIVEFLQADGEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRKADEGLITGWLFFRYMAIGGYVGAATVGAAAWWFMVSPEGPHLSYWQLTHHLSCFTEPEKFAGHECSVFKDPHPMTMALSVLVTIEMLNAMNSLSENQSLTVMPPWINPWLLGAMALSMTLHFVILYIDILSGVFSVTPLNGEEWFAVMKMSIPVVLLDEVLKFVARKYIDGTKESNTGQSTTPSSIASLHVNFTELAPSKMILQGRRNKLCSCSSTIHFLASPLMSLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCY1</accession>
    <name>A0AAV4MCY1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_693461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002064">
        <property type="protein sequence ID" value="GIX69552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCY1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16045" checksum="FAF501BDF61418F1" modified="2024-11-27" version="1">MELRFLEAFGHSFPSNQDIPDFEYKVFEIALSESQVGVSRPILSTFPPENGKITFPNFTPSQPASRLIFFVPLPPEALLKRGKLLFPNFTPSQPVSRLIFFVPLLPEALLQVSNSRCRLSSSVGVEFVMSFMVIRRRRAKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJH6</accession>
    <name>A0AAV4MJH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_725691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019786">
        <property type="protein sequence ID" value="GIX71757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="17845" checksum="71D3040FA45B7C9D" modified="2024-11-27" version="1">MVLIHMMMKYAHLVSARKTLLNAAHPFAMKMSLRSRLLFLSHDVRAALPDSKLRGGTRPSVNVGQWFVFWHGRNSLALSRLAGKLPFVAAQLAPSPRTLDCSGPLKQKQPSRSQAIRMPTLLALFAQQVAWAPALFFVYWTTEDASVFIYLFTASRFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN65</accession>
    <name>A0AAV4MN65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_128051_1</name>
        <name evidence="2" type="ORF">CEXT_611891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019937">
        <property type="protein sequence ID" value="GIX73293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="306" mass="35272" checksum="A541FCD808776EE2" modified="2024-11-27" version="1">MKVKKDPNFHSDPSIQTQVKSKKHIKKRKKNKIMYESLPISDVSTLPTCEDYDEHSVNSKIGSCEIRNGILKIRLSKLPNNKKGMKEKKIMKCLIVKQLPLMDVNLYHKEKCGKESLYEVKESSSINTVQDANVDSLNNDRKSNINELNQTLTSISNVNKTLHEDETKEFKTSEIIKEPLKECLKNDPAKKESFKFLENNHSFIEERSINNEKEHVCTPTLENEMNSMISINKPDNPDSKITCSIKLSMITRLPLIKDVSNYTNDQTISIQSDIAKEELLKKSSFTLKIIYQILKVYDNFEKTQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN82</accession>
    <name>A0AAV4MN82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_288321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002445">
        <property type="protein sequence ID" value="GIX73810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13320" checksum="70B71BDC2712619C" modified="2024-11-27" version="1">MSGTTQCHSPLSTICPYLYLHSLFSPYFAVKTTDLIVFVTGHYNSFLRAFWVVFETLCSCRKPTLHCSTCIDLLPAQVPLSTIGSHDAGHTDCFTKSKWTNTYPSTPDHIIVTFLEALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTN4</accession>
    <name>A0AAV4MTN4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_242641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020046">
        <property type="protein sequence ID" value="GIX74249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043719261" description="Secreted protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8515" checksum="D429DCC8E78FA344" modified="2024-11-27" version="1">MLSPKSINLRFWGHFFFSCFVFPLRGNVVKAFVPEESRRFYGGTEWCSCDFARDFGNALSKGSVGGFQFDVYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTW3</accession>
    <name>A0AAV4MTW3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_341841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020154">
        <property type="protein sequence ID" value="GIX75275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="455" mass="50329" checksum="C1F24CA4DDF26E13" modified="2024-11-27" version="1">MSIESYNQPDPASRHMSIESYNQPDPASRHMSILNLDSASHNASIDSYNQLNLDSASHNALIDSYNQLNLDSASHNASVDSYNQLNLDSASHNASIDSYNQLNFDYACHNASIDSYNQLNLDSASLQSREECFLRYQRRKIKRERMRLWKTNSWSQRTRRDGRTSLQRSMISAAAVAAISAAASQYVETSRAMDAEDIGNQVLSKNLVPSIVLPPVYIRQASTRRTIPLEEFKPHFTHGMTDNSHLLKQTNTASSQNTKQRFTPNHSSVNVCNVDQRFTPSSMMASFPNHASIDCYNQPSSDSASYNARFDSYNLSSSNPASHPALIDSSNQPNSDPGNDSESIDSSNQPNSDPANDTESIDSSNQPNSDPANDTESIDSSNQPNSDPANDTESIDCSNHLNSDPANDSGSIDSYNQANSDPASHHASIYSYNQPNLDSACLQVSEEYVLRHQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYN2</accession>
    <name>A0AAV4MYN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_81571</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002781">
        <property type="protein sequence ID" value="GIX77657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051968">
        <property type="entry name" value="ZnFinger_Homeobox_TR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45891">
        <property type="entry name" value="ZINC FINGER HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45891:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX77657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="224" mass="24162" checksum="8C829D3E32203301" modified="2024-11-27" version="1">MEECSENKEQQVLEDYIKTAKAIAEKIVILIPIGSINATGVKELLLLDKAILPVIIKRSYIGRGEKFHYNSVSHLHKLKLSMKENNAPNSTASTPVSSTSVASPSSPSVVTTSSSNASTLDIHVRSVLHQSKATRIQELVLSGELDLTSSLVERPDSNPSSEIAQTKTSESITTPSENSSNNLPTTTSQTLKTSGNSCFTNICNIVFDHHTSDLLSSVFISFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0C5</accession>
    <name>A0AAV4N0C5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA topoisomerase I DNA binding eukaryotic-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_461511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002777">
        <property type="protein sequence ID" value="GIX77644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0C5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA topoisomerase I DNA binding eukaryotic-type" evidence="1">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14336" checksum="E41D3F4FB531D84F" modified="2024-11-27" version="1">MGYILATSSVWPSSQSISEISEWETGTHGSLSHKAVINMKERGHFFPGGFARTVPITFDIYIEEVWEEQKVGGGIKWQTLSHNGPIFAPAYERVPNHVKFYYSEYRNLDIGCPFIIWSKNGADYGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4E5</accession>
    <name>A0AAV4N4E5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_804261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020444">
        <property type="protein sequence ID" value="GIX78888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="15227" checksum="6D397C017987ADBF" modified="2024-11-27" version="1">MGLEPESCGTEHQSHSAISSCLCRCLCLKEVHILGFKQISSSFKVHSQEHFAEHFSTKKFDSNRLAINQKCKRERLCFLRRFEQKKRRYEEEMMAEYLSQRNGNSKLFNIFLDSCCRKRNECEVFEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5A4</accession>
    <name>A0AAV4N5A4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_804131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020444">
        <property type="protein sequence ID" value="GIX78866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5A4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="16146" checksum="1FDE7AD1757E627D" modified="2024-11-27" version="1">MTTNRNDSKGSKARGKILHSLDFHSFTEFRTQKGKIRKAFHPTSHTVHDYSTQYSATHLFKTPYTSRVHGDKLSRPKWISIHTELVKLGKLYKRNKEKEKKKRKAPHFKQRNDHSYPYLLHLQNTRDITGYSFTTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7V0</accession>
    <name>A0AAV4N7V0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_289821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020630">
        <property type="protein sequence ID" value="GIX80890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7V0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9926" checksum="75FA2B14E973B11A" modified="2024-11-27" version="1">MNNSEVRHFRLVPFFYFFPENNIAILGDLPHLEFLEQKAIFGKAECEIIRDGTFVVPQKQEREVIHCCSAIGNRKNSAFLMAGSVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK21</accession>
    <name>A0AAV4NK21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_797411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020936">
        <property type="protein sequence ID" value="GIX84168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="13904" checksum="B25886BB4F2C6AD3" modified="2024-11-27" version="1">MCTSANLGKYSPSRVEGAEKQRRQFFCCHSRVGDGRNSDEGEKRTALERRRMGEARGKGSFFVSMPPPPSNKLCEVTRIRNNLIAAAAAEFSKDTVLQDGEFAGSGKIRGTHEYGSTEGEGQKNASTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLE7</accession>
    <name>A0AAV4NLE7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_360591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003533">
        <property type="protein sequence ID" value="GIX85642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7749" checksum="175CB2931F5AB45F" modified="2024-11-27" version="1">MFDNALQHWAPPIGSNFSFEVSKEKQQKRAKKPVEVDKKGIKENSKFGSMSKVITEIASSAFDRPLLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMD6</accession>
    <name>A0AAV4NMD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_730221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021111">
        <property type="protein sequence ID" value="GIX86005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11961" checksum="621A0F6F6DA75A18" modified="2024-11-27" version="1">MAPNEKPGPPNEFVSTPVVEKIFVYVLQVYQRLWILGLVRNHPVCGQQGDYVPHFWVRFSIPFYRIRLLIPGAILGCHCTTRWCDVIVLLYFKNVERNRSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPW9</accession>
    <name>A0AAV4NPW9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_390191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003526">
        <property type="protein sequence ID" value="GIX85589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14644" checksum="053FB827A1579CA7" modified="2024-11-27" version="1">MKQLRCKSILITSNDKQKMPASGISFSIRDSLSASTLGLLHKEGKGKKEGGILSRKNEKSEKRLFAKVALAERNLFVNRKRNPIKKTEDSRIQSKRLPKIFCGVPVFMQLFLALLAFFFAFLLPHCFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTZ3</accession>
    <name>A0AAV4NTZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_488561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003711">
        <property type="protein sequence ID" value="GIX87780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14301" checksum="7D0B6455817C50D1" modified="2024-11-27" version="1">MLQNIIKISTLYIHYTNGTWVVKIAGSKLRRFPQPDPIRSGQGIVLNTVLELLMHFLTKNQSMHTGEALNAFQPFDCMVLHAFQSQHVGSACDISLIPLVEMFQFWPDESNYNASLSPQALLGRLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWP4</accession>
    <name>A0AAV4NWP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_277621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003848">
        <property type="protein sequence ID" value="GIX89327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12571" checksum="977F7C5B3F530CBA" modified="2024-11-27" version="1">MFRNRNIVHDFVNHIVYHRSSLHRHHFDQTPDIRASFPMLTSTSHSQLSEVHDNRSAPMFRNRNIVHDFVNHIVYHRSSLHRHHFDQTPDIRASFPMLTSTSHSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWR7</accession>
    <name>A0AAV4NWR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_95394_2</name>
        <name evidence="6" type="ORF">CEXT_804431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021416">
        <property type="protein sequence ID" value="GIX89335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX89335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12975" checksum="46B6B03ACC423E5C" modified="2024-11-27" version="1">MKPGCFVVRGLGYSFSIIILICYISAIAMRPSLHDQFHIIRLNLSIAAVGTMISFFSVDFKRHDFEACRVLSGFIHYFYLALGCWMCILTHALFNGFIKGVVDGRVRFYLLVGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXB7</accession>
    <name>A0AAV4NXB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_99081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003856">
        <property type="protein sequence ID" value="GIX89383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18282" checksum="766DA64F325631C2" modified="2024-11-27" version="1" fragment="single">MIDKNKDGSLAWRHLAKADKGRRGDERPNVGRSVTLTLEADGGSWREEIVLPLKPDVDREKSTHNFSSNANYLAERNGSFFYVLTGVVVTKDRRFYNFRHLNDAANDYELDSKDELAVVAASGNELLPQSETTAEAGTRKTELFEFGGSRFDLQRFSLPPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P883</accession>
    <name>A0AAV4P883_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_715991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021630">
        <property type="protein sequence ID" value="GIX91916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P883"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14266" checksum="A53DA171F38C2369" modified="2024-11-27" version="1">MNKSCTEMKIWNSDENNVKSYIKVNNCTYNESFDYPDHLTFNEVFIKEIFLCTLMLIFAVCDNLLVFVTLTEINLKISRVYKMMMHLIISDLIMILSRFLSRWLGGSVCNGRPAMQLAKSCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PB32</accession>
    <name>A0AAV4PB32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_314011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004351">
        <property type="protein sequence ID" value="GIX94243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PB32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="20400" checksum="48651524D2743928" modified="2024-11-27" version="1">MIRRSVKEGSRIHVKIVRERQTLERSRSIKRQSKEGDGAVRYFLAKGNFHANERELFSGWPHLFMMHPSLFRHLNFHSVPLKLNDFKTIRACLNFLRYAYAMLLPALFLEGVGVDLRNPPSLPRSLSTPFFPFYLGFIFSLSSPRFKGGEISSLVVLRRGAAPSEKDASFPVVLWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKK5</accession>
    <name>A0AAV4PKK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_529011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004681">
        <property type="protein sequence ID" value="GIX96693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="20409" checksum="737033EC12111222" modified="2024-11-27" version="1">MVFSGVVIRICLLQQLPFWVCTVVAVSASYGKRRRLRRWLWWLRRWPWNHRQLRIRRWVKEVTEEATVATVDMEEEMARGLGGYGGYGHGGYGGSGLGGYGKGLGGYGGSYGGGHGGYGLGGYGGHGGYGLGGGYGKALGGYGGYGLKGYGKGLGGYGGYGHGGYGGYGLGGGHGGYGGSYGKGGYGGSSYGAYGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNU8</accession>
    <name>A0AAV4PNU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vang-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VANGL1</name>
        <name evidence="7" type="ORF">CEXT_738651</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Vang family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004823">
        <property type="protein sequence ID" value="GIX97818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009539">
        <property type="entry name" value="VANGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20886">
        <property type="entry name" value="VANG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06638">
        <property type="entry name" value="Strabismus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX97818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11886" checksum="C5A206CB62906505" modified="2024-11-27" version="1">MQSILDHLALCLSHDLSPKAFLEKYLVSSPVLQNDREHRPSQTWALVCDTLLSRPVEAGCIFMLRQNDISLLVTVSRLPHLCITEEVIDPKSNKFVLRLNSETSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTJ6</accession>
    <name>A0AAV4PTJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_718821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005067">
        <property type="protein sequence ID" value="GIX99593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13823" checksum="3055B82611343159" modified="2024-11-27" version="1">MKQLILVLFETTLSLPPVFYFRHGHFFHVSDHTIRKDLKEKKMYSSKFNSNCHQKHMKTSRRRKLFAVDRKSDLYESSNIKILGASLVNVLIEVVFSCHCPGDTMSLHPLLSLGNVSSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTU9</accession>
    <name>A0AAV4PTU9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_20251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005249">
        <property type="protein sequence ID" value="GIY01043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043573715" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9129" checksum="061357EB76B80A6E" modified="2024-11-27" version="1">MSSKATVCFRIPHSCLLHVLLVCMSTDDTCVQYKDTWALSPNTSSHANEVRNASLGHFVCQLNNLFRMSPDVVGDLCVCLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW92</accession>
    <name>A0AAV4PW92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_720771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005048">
        <property type="protein sequence ID" value="GIX99447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15406" checksum="F7C4ACF3F7838305" modified="2024-11-27" version="1">MFQSCRRTYIKSRPVLKNLDRFTSQRLIQGNHGNSFSLTEKSNETTRVLILLWLRHTHLEPKPQQPNLIYRAQVVCALICTQLKRACAVILAFVQFPFYMLELPESRFHHCVMFCDNTNSDWPSLNYFAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q123</accession>
    <name>A0AAV4Q123_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_798571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005568">
        <property type="protein sequence ID" value="GIY03358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q123"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11202" checksum="E4CDA39A89E78B67" modified="2024-11-27" version="1">MTSQFDTNVNFDSSMVSIFDADVKLHSSMAPQFDIDMKLPISIFTNEWLHKLAPMKQMKKMGVLEREEECCNKSFSEKKESGIFPSPAHLATGRDREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q504</accession>
    <name>A0AAV4Q504_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HECTD2</name>
        <name evidence="8" type="ORF">CEXT_495391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01005451">
        <property type="protein sequence ID" value="GIY02493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q504"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF444">
        <property type="entry name" value="HECT DOMAIN CONTAINING UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="40"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY02493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11652" checksum="8357F25D66FF7F36" modified="2024-11-27" version="1">MSTNSPSEKLLAILNPERILGNLKELQFRFAETVPEIHDGSDRVPVGGMGEMTFKISALNHNTDMLPISHTCFNQLVLPRYKNRDILREKLTIAISNAEGFGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8I4</accession>
    <name>A0AAV4Q8I4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_459191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005872">
        <property type="protein sequence ID" value="GIY05704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8I4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8998" checksum="ECBB25F615E41842" modified="2024-11-27" version="1">MRKAKDGGGEGIVDRRKCKKKKKRSKGKLWRSNPTGSQKPVSPPVVCPSYLLNVSKKCVVIRFLDFLNTEAPDFHFTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBY2</accession>
    <name>A0AAV4QBY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Vitellogenin receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">yl</name>
        <name evidence="20" type="ORF">CEXT_626511</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDLR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005882">
        <property type="protein sequence ID" value="GIY05814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042562">
        <property type="term" value="F:hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000009">
        <property type="entry name" value="Low-density lipoprotein receptor isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000024">
        <property type="entry name" value="Low-density lipoprotein RecePtor related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000002">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000011">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000241">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF14">
        <property type="entry name" value="MEGALIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00058">
        <property type="entry name" value="Ldl_recept_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51120">
        <property type="entry name" value="LDLRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 14" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 20" id="KW-0675">Receptor</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="993"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="16">
        <location>
            <begin position="810"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="19">
        <location>
            <begin position="945"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1069"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1098"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="310"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="971"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="GIY05814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1136" mass="126015" checksum="88546DE68DD864D2" modified="2024-11-27" version="1">MTTFQRREVMKYHAQSPEGIAFDYRSGNLYWVDSGKGTVEVILTRTPKASVVVSNLPQPMDIALVPNIGRMFVSTLGDVPLVRMYDMDGKNGRVISAIVGLPMALAVHPTASILYWADPKMGAISSIDYMNPRSKPNTLKTGIGNVMSVTATEKYLYWTDSKYHVLHLGKHNESFSHTISLPGLRSGLVPRRVIYAAAPLSKRSFGSPDCTNNNGGCSYLCLTSPGGRTCVCPTGMLLSQDGITCADTKCSSTEFKCLKSEKCIRLDYVCDGIRDCPDGSDENCDGRFQKCPKNDFRCSNGRCILQTWKCDGSNDCGDNSDEAGCPPPMNCTKEFTCADGKCVPSLWQCDGESDCKDGSDEVNCHTTVCDDATQLRCDHGQCIPISWACDGAPDCMDGTDEKDCSQKLIHCEDGSDEVNCSELNTTCKAGRFACNDGVTCIYMHEICDGYKDCNQGEDELTCNRTAVQCSDEEYFCKNNSHCIPKRWICDGENDCGDGADEPEDCGKDIHSMPVSICEDYSCPVSGECIPWDKVCDEELDCGDLLDEGPLCSKACTGDAIGCAHKCQKTPQGSKCSCYKGFTLSEDGLACEDLNECDIPGHCSQFCNNTKGGYKCSCAEGFILEFDHRKCKAGGPEPYLTYMLPDEIRGVNLYKHQTIKSRKIAQASEMRGMDWDSSDGTWFWADWEKKTINSWQIESGSAVLVNTTVRPHYLRRDWLTKNIYYTDDEGSIVCCTGDGRYCATVVKHAEFHVNSFDIAPTYSLMFWTIWMLKPEGFGKIERAELDGSHRTEIIGTNTYWPSAVTVDHILQMIYWTDAKLRLLECSDFNGMKRRTLVSKNLDHAFSMTVFEDYVYWSDWFTSNLMRCNKFSGANISRIYHGSVKAEVLLVEHNATQPKGINRCENSGCPNVCLPTQTSFVCKCDDHFAQLESGCEVNAAALPVESVDQTCPDNFCLQDVDCVIIRGRYVCKCSTSYRGDRCEVKVALAENSGDAGWVVGVVLALLFVGLIVMVTFFCRKNRDKLNKMGESVTVSFRNRRLSRRGSKLIDCEEDGANDELDLGKKSTNRMGFSNPFFGKKAKTQPSSKPEEGFKRWASQDSGNSAFADDSASADEPSGFRVLDAPRRTTDRIVQIFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QN69</accession>
    <name>A0AAV4QN69_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cuticle protein 16.8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_654901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006419">
        <property type="protein sequence ID" value="GIY09699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QN69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF235">
        <property type="entry name" value="CUTICULAR PROTEIN 73D, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY09699.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14525" checksum="B5B7AEB45940C653" modified="2024-11-27" version="1">MDCSMLLQESHPPHPFHFGYDVLDEHGNKQQRQEQGDQHGNVKGSYGYVDAHGVYRQVDYVADHSGFRAVVQSNEPGVANEDPADVKLTAKSPPHHVLEQQLSKVEHGYADPKLYIKPASKPLYKESLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTF2</accession>
    <name>A0AAV4QTF2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_459661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006799">
        <property type="protein sequence ID" value="GIY12520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043439204" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9342" checksum="6CFAD7F948E6FB45" modified="2024-11-27" version="1">MVASCFIASNVLGVLLCVWDDIFSTDSYMLSCRKVTLSAVCSNACFWCAFGGTVRRCSSLAPTSYQTFLKNRVFDDLDSFEDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R750</accession>
    <name>A0AAV4R750_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_77571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007493">
        <property type="protein sequence ID" value="GIY17290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R750"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8389" checksum="3B4EAB1E982E1315" modified="2024-11-27" version="1">MSDDNPPKPTIAKAPFNAPNPRLILGYSEILIAVQVPYTLAQKSNFFDSFNMFRRNPDVGISNANSTDKISKAAGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RB57</accession>
    <name>A0AAV4RB57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_128791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007561">
        <property type="protein sequence ID" value="GIY17916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RB57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="329" mass="37887" checksum="A0F7FC0CD4ECE949" modified="2024-11-27" version="1">MQEIPKSPKEEEVNSSQKAEIKPTNSKVIKPKNSKAIKPKNSNTIKPEESNVIKPEESKEIKPEESKVIKPEESKVIKHDESNTIKSKSEESKVIKHDESNTIKSKSEESKNESEWFDDDDNTPRKESQRTHEQFEKDSESSTPQRISYLPLVRKVKEVLRPSQHIHKKKSNDESAFPEQNDSERRQQRRQKQLERTFLLRKAESSSDEDDEILSIGERSTSRNIGAQKIDSMLEGVEWMPMVSSGFVLDEQVSHLKADRMKEATARSSAQLEGTSFTAVDDDTSYSFLKELKQAIRKAERKTQFAEPLTVYELKHNHSVKSLQYSKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RL35</accession>
    <name>A0AAV4RL35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_289311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008160">
        <property type="protein sequence ID" value="GIY22519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RL35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="17700" checksum="3D5F4DB2AE972B81" modified="2024-11-27" version="1">MGLRRVSRSSLSPNCIRANHSFDASPVFRDRAGVRNVLGRGRFALQMNPRPRIANESPDTAGDLELLNPSGVGKIPFNAGSRKVRERGAAIFGQFQEFKIILLENSNDYWQCSNKPRVPDVSEREGGGGGRFALQMNPANVPGRAGRPEAPKSVRCWENPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNJ0</accession>
    <name>A0AAV4RNJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coiled-coil domain-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CCDC6</name>
        <name evidence="3" type="ORF">CEXT_520951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008063">
        <property type="protein sequence ID" value="GIY21881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019152">
        <property type="entry name" value="DUF2046"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15276:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15276">
        <property type="entry name" value="H4 D10S170 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09755">
        <property type="entry name" value="DUF2046"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY21881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="382" mass="43806" checksum="3CF73AFBFA0AE636" modified="2024-11-27" version="1">MADSASESDSSSVDGLCSVPISLTREQFQKRIDSLQQENKVLKLEVETYKFRVKSLQEENKHLKQVSVNIQAKKLNKKKNSLEEECLTNDLFRKLSQLRQEKVNLEQTLEHEQEALVNKLMRKIEKLEAQTQAKQQNLEQLRREKVELENTLEQEQEALVNKLWKRMDKLEAEKRMLQEKLEQPVSAPPSPRDINKGDTAANLTLHLQHLRNEVAKLKTQLLNAQQEHTEKMAQFAQEEKNVREENMRLQRRLQMEMDRREALCRHLSESESSLEMDEDRQMSEMSTSSHLSSRSMLSPAPLMHSSFSSNPHSPATSISGSREASNHCYHCNQSLSQINAMPSPSPPPMFSPETQKISHGAGSINRGKSQERFLKPAAPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQ72</accession>
    <name>A0AAV4RQ72_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NLK</name>
        <name evidence="4" type="ORF">CEXT_278871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008105">
        <property type="protein sequence ID" value="GIY22113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQ72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY22113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="20124" checksum="19758E30D1B4D708" modified="2024-11-27" version="1" fragment="single">MVLSALDILQPHSADYFQEIYVITELMQTDLHKIIVSPQPLTADHVKVFLYQILRGLKYLHSANILHRDIKPGNLLQRVQELDESKHMTQEVVTQYYRAPELLMGASSIIPPLLIFVSWVYILQSYWSGRILLSSSNPNTTIGNDNRFAELPRKMIPKTACLGARSHMMRVELHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RU17</accession>
    <name>A0AAV4RU17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_294611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008328">
        <property type="protein sequence ID" value="GIY23876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RU17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15451" checksum="4263D71BA8279CBC" modified="2024-11-27" version="1">MNPNRSYDIGDDQTQFRNFRFKIFIRIMRLQSHILPQDSLELIPFSGMVQLRQTISSKSLPPTPKWGRIGFHYRFIGLNFDRILGADFFRAMCVRPPLGVAQFELEKSFLSHYQGFRLAGCPGYESGCPGGSGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SH41</accession>
    <name>A0AAV4SH41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009455">
        <property type="protein sequence ID" value="GIY32096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SH41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20413" checksum="5CB08FBDE6437335" modified="2024-11-27" version="1">MNKRSIYHNNCSRRTAELPFYQSQQHADTPKYRLPARVAHEHWCVEQTIFKRGIDPPPTAAPSKCLANRVVPTTATARRESTNRARNVRYACQVCVIPLHPLPPIRGQAQEMLMNCSRLPSPSGKGGLPRPDTPDFNLAPFPTPNPLSCLRGREQAFFSFCHTVFFFFASPIGMKCAMTAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHW5</accession>
    <name>A0AAV4SHW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_343091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009425">
        <property type="protein sequence ID" value="GIY31802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11149" checksum="A4E675319667BB34" modified="2024-11-27" version="1">MHLQVLENNRSSGEFCGKTKFSGSYGVKIKHCVCDDCRSSCSTLDDSTYSSTSEGEEYDTDREAAEAEENDPNKLLGTWLGQLQQLERVSVWFDLFNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SK94</accession>
    <name>A0AAV4SK94_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pericentrin/AKAP-450 centrosomal targeting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_492081</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009740">
        <property type="protein sequence ID" value="GIY34195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SK94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028745">
        <property type="entry name" value="AKAP9/Pericentrin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44981">
        <property type="entry name" value="PERICENTRIN-LIKE PROTEIN, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44981:SF2">
        <property type="entry name" value="PERICENTRIN-LIKE PROTEIN, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="8">
        <location>
            <begin position="903"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="592"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1038"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="8"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="217"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="304"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="398"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="692"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="597"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1038"/>
            <end position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY34195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1089" mass="126703" checksum="2892B7CA7555D803" modified="2024-11-27" version="1">MITLESSLRAARKDLELEQVQVDTLLQELGSLTGYQKRLEQDYDTIQEMMQQKERELATLHEETDAQMKLEAEVECLERELEDQKSIELELRQIMRQMETALEVSKNTLKSENAQWRLRVESLEKAHCLEIENLKKQNEVLCRNISSSEVEDIDLVEVRKEILYDAGVAFGFHDSKAYGDLIYALLKKAVDIKLSQMVKKHEAFVKEINESWENKIKTEFNTKNYNLNSQCEELKKENLLLKEKFQDQNQRLSCEKDSLWQTKLKESEITLRQELETKYGVEINDLKCALDNVSKEKSSTVIKVKDLTRQLKEQKLKFQAHKNQLLKDFEDKIISAKREQEKLEGKQQTESIFKQEIERLQTELHSKLEKERMVEESHRQEISKLHKFFETRWVDEMKKIQEIQIEELKKLKDSKERNVEALCNHLFAQYSDKLKKLQEDYAAQLAEERKVFISQHKAELQNLQQALEKRFENEKQNLLEIKEKEMKNISESLEKKYSKKITDLRKDKSLNNHNMSSGKDSRNPWEEERLELISLHNKEIVDLKEELEKKYDMMLQSQMISHEVEMKSLEDAYSQKVEEVHELIREARRIASKSCHSDSGSNRTTTPSSEMSSDEACSSCQEDMLPGNKHILVNKIHQDGKRVLNLIESSLATTSTEREARLWIEERKWIVKRIQILTPEVVDNPTNLKLIISNIVDELLNARQKLINYNEEINKNEEKFSQLEQQLDTEHSKVYIIATNLSHQTKVIKELEALLNSRTSEIIELKKYFANVNSTQYQNLTGKDALSQNHSENLSSSYDVGCLRSADEPKSADKFSMFLPELDSLHLQKSGDEIEVTREGMASLPQLTKELDQYLDGSISPESLGQYSRNDIFSVREELMSKLSDKGPQASYEAKLHGLYWVYKRSMSYSKSLVYQKKYLLMLLRGFQVTEKVTEAWLHRMDNDISPRPQGDDTVINEPPLRGRSLFRSAALVAVAIQRMKFYVRRWRFLARIPSSQVVDAEIRTVFLGYSAFSPTLTPGGCNSSLLSLSSKATSISGTEHLSNSQSLVNSRPGSKTKEKYSTPDKRQLIEYVHRLETLQKHLGLDNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SM11</accession>
    <name>A0AAV4SM11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UNC93-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CG4928_14</name>
        <name evidence="7" type="ORF">CEXT_740301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-93 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009859">
        <property type="protein sequence ID" value="GIY35115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SM11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY35115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18149" checksum="C9B3387C3C5C2B0F" modified="2024-11-27" version="1">MFPVTGLQSLSILYFFATFSCILGPIIDQKIGIRWTFLAVSLLEACYVLVFHYYHPVALVICSILLGLGLGPMIRSYYFWGHLAATIIMEYAGTMNNGGSSLSNSTEDVTVVQRTELCYERLCQNGIYPTEIETDDTSSPPAGIPTNATMVFIYVLPRALQSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUX3</accession>
    <name>A0AAV4SUX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_548751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010122">
        <property type="protein sequence ID" value="GIY37094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12061" checksum="BC581FC1520C9FE9" modified="2024-11-27" version="1">MENSKRQVAGRAGEQRTAPCTRSEVNIATTLAKDGASPNLADVEKRLRGIQLSLLRLHLSMKCRRDGYELGEPTTPCSVPNCLPMKRVLGHEDMPKRKSMHSKLLCKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVL5</accession>
    <name>A0AAV4SVL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_154651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010298">
        <property type="protein sequence ID" value="GIY38398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11807" checksum="CC5E6742732A58DB" modified="2024-11-27" version="1">MGHPLIRRHFGLLVFDASNECPTLVRKETMSVQSHSAFKLLQRWLFVLQMQMLWISKDSRTEVFHVKFWEQSVGLSLIKQCGVIRTPIYKNMWKTINSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXK1</accession>
    <name>A0AAV4SXK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_570551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010246">
        <property type="protein sequence ID" value="GIY37981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11488" checksum="584CCA6202FA47B6" modified="2024-11-27" version="1">MILYVSVKNIKCYRGNYLILLMQIIKTTLRCSVSCLLWIATGCPSHWSAPCTPGETCSGGSKRNWRRPRLKARRPGTARFADRSSDVRTPLSLTGTPHTLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T6W9</accession>
    <name>A0AAV4T6W9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_74602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010716">
        <property type="protein sequence ID" value="GIY41459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T6W9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15377" checksum="2F851BB2DE73E46F" modified="2024-11-27" version="1">MTGFKQEEKMTKPVRHFGYFIKKIGKLHPSAKRLCNSKHTAFCRVKHLMRNRCSLSLVQTTSRRPPLRRPHPHKQQNLGRKCSTSPCVSRRSSSRTRVIHLRLRPKEFLPENMEVPRAFDSLFERGYMFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIG1</accession>
    <name>A0AAV4TIG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_667491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011279">
        <property type="protein sequence ID" value="GIY45509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12124" checksum="0F3C4180FE05B05F" modified="2024-11-27" version="1">MDYFTVWEWPLSMYGMASIYVQGMASISVWEWPLSLCGNGLYVCAGMSSFSVKEWRLSLCSNCIYWDLRYNLRPFTLRTTNIKADLGVTCSAPILHSQCAITIFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS54</accession>
    <name>A0AAV4TS54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_147071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011771">
        <property type="protein sequence ID" value="GIY48889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15438" checksum="2427ED508E2AF84A" modified="2024-11-27" version="1">MWGLILSCNYNDNGFKPQPSNMLAVSLTNGHKLGANLLWPVRLWSRSRFPNKIIVTDTFSRTRPDELKWLRRVISRNWLLAFAFFGSVQTRSCKGNENVPVLLFSIKYFIQVLEFKNVYHILLQFRNQNCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U101</accession>
    <name>A0AAV4U101_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_172116_1</name>
        <name evidence="1" type="ORF">CEXT_444231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012107">
        <property type="protein sequence ID" value="GIY51430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U101"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9638" checksum="A7F51925CCB1B13C" modified="2024-11-27" version="1">MITATKLPKIQIKKFYGNLLSYLSFWGPFKKIHEDKNLDDVDKFHYLAQSMLPGTRAYELIESYPLTSGKLSEGHFCVYGAFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1D7</accession>
    <name>A0AAV4U1D7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_810051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012132">
        <property type="protein sequence ID" value="GIY51608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1D7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="46" mass="4911" checksum="2EB484F2CEE62877" modified="2024-11-27" version="1" fragment="single">MSIIPDSGTRSSAHHYRADRLHVAIHTIADSRAGQQATKPVITVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2Z2</accession>
    <name>A0AAV4U2Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_174821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012206">
        <property type="protein sequence ID" value="GIY52169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="13747" checksum="D117ABACFE3BAAF4" modified="2024-11-27" version="1">MDKCAEFNISGQRRVFSRMQKLITTLGEGDSSSQTLTTTTEISYKLSSSSVGSAFNNTSLPSLTFLPTVAQKSLTLRRNVQQRLDMDSTLEQSRSARAVLAGGATLLADSDDHSITTVPLSRAVVSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9M8</accession>
    <name>A0AAV4U9M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_666881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012514">
        <property type="protein sequence ID" value="GIY54410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12010" checksum="A97FB9268F0C5C19" modified="2024-11-27" version="1" fragment="single">DSTPDVNAYGDFSSLLNYLIKCAKKRRAFLHDTREVAFQIAKDISPEEFRSMSVEEKSPHATLHRRLVSVVLVSCSSPKRARGWQYAPSDIVSSSSSVYVSSFTPHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCZ6</accession>
    <name>A0AAV4UCZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Estradiol 17-beta-dehydrogenase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hsd17b2</name>
        <name evidence="1" type="ORF">CEXT_620101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012663">
        <property type="protein sequence ID" value="GIY55664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16721" checksum="E7B578A6DD387192" modified="2024-11-27" version="1">MSGGADELKRSCSERFCTLHVDVTQDDSVQKAKEFVEKNLGKCELWAIVNNAGIYKGMIAEFTKISDYQDVLDVNTLGQVRVTKAFLPLLRKSTGRVVNVNSITGRISLAHITPYTMSKCAAVGFTECLRRELDAWRIKVISIEPEFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDZ0</accession>
    <name>A0AAV4UDZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein Gawky</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gw</name>
        <name evidence="3" type="ORF">CEXT_575101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012700">
        <property type="protein sequence ID" value="GIY55936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035195">
        <property type="term" value="P:miRNA-mediated post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052068">
        <property type="entry name" value="GW182_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032226">
        <property type="entry name" value="TNRC6_PABC-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13020:SF25">
        <property type="entry name" value="PROTEIN GAWKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13020">
        <property type="entry name" value="TRINUCLEOTIDE REPEAT-CONTAINING GENE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16608">
        <property type="entry name" value="TNRC6-PABC_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNRC6 PABC binding" evidence="2">
        <location>
            <begin position="174"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY55936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="279" mass="30071" checksum="3110C2AA883E011C" modified="2024-11-27" version="1">MFHLTATSVASAASILQNPQPSTFDVVKSNLESINGLHSEFRDLSVKDTTSQGHSRLNQWKLPSFEKDDNPTSNENNGCNRNDASNEFSRAPGSITKSSSANSLASTTASHSSSNLQPLSENTWPDMPRSQNDTWSDPNDSNNSVQGSNDNIGNSNDSSTDGNSNKHNSASENKDSPATSSNPSTSSSSQSYNLNDLVPEFEPGKPWKGTSRIKNFEDDPHVTPGSIAKSPLSLNSIKDSDLFSWNTKQNVPNLSTSSSLTSSTWTFSPPPSSQNRQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKW0</accession>
    <name>A0AAV4UKW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMRFamide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FMRFaR</name>
        <name evidence="8" type="ORF">CEXT_662671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013050">
        <property type="protein sequence ID" value="GIY58364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052954">
        <property type="entry name" value="GPCR-Ligand_Int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641">
        <property type="entry name" value="FMRFAMIDE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46641:SF22">
        <property type="entry name" value="PROCTOLIN RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="80"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY58364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="24265" checksum="816FE6213A277A1C" modified="2024-11-27" version="1">MYETVNYEDNCTFLENVLCNATNCLYSNNDNCSNSDLVTNVTPSLTHINPDPSLEEFQLNSRFWIQRVLVPIIMIIGVIGNTVTIFIMTQRRMRSSTNWYLAALAIFDMSYLVFSFLLSLQHYPNIHDAHFYLYWKFWPYMLTITDASSNSSVWITVTFTIERYIAVCHPMKGKVICTESRAKKMIIIVFLTCFFSPCPLPSNGSQWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULC9</accession>
    <name>A0AAV4ULC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_142511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013078">
        <property type="protein sequence ID" value="GIY58583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="15995" checksum="EAD76C333A29C79B" modified="2024-11-27" version="1">MKLPTRHYKSQNLLASPGQQAATIAENNAFRLMLLFTVRGIKSLINRSSAGIIVKSNISYPFKANCNIEATHCPQPRQRQKTFQEPGFGCSTIYYRHPLNQLKLSCDQQLGVHFRLHGLMAKYLPLSNFDTAPSCPLRSAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZS5</accession>
    <name>A0AAV4UZS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_205511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013704">
        <property type="protein sequence ID" value="GIY63134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9649" checksum="C5B8BF96F2355B17" modified="2024-11-27" version="1">MRVLPGRTITQRKDISLQSVRRKYPHLVEWRLGKEEGRFDRTENWVRFSMESMRFLRACLWWQKVVEAISLRSKKKANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZZ5</accession>
    <name>A0AAV4UZZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_122731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013757">
        <property type="protein sequence ID" value="GIY63546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14113" checksum="0A59212ECB6FCC74" modified="2024-11-27" version="1">MWQPQPRCISFPGDVHNGVAQSPVMHHIPAPGQGGRGWEIHPSKTPIRNFHLQLLTPECLSRTRLLWSTHCTFPLRFFSISINAYTSIYTHSRSALLPCAVRRGLRIIKEKYLRSSPGYHVVCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0E3</accession>
    <name>A0AAV4V0E3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013775">
        <property type="protein sequence ID" value="GIY63700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10823" checksum="64B4CCD0B418C6B6" modified="2024-11-27" version="1">MRQEGKTFFFLQRMSPRMMQSVCVVDAQNKHCKAETNSSQKAEVKGFYIGQLVLVERNQTEDNGIEMAKSVEQLLFIDAATSCDLELKSKSKGTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V199</accession>
    <name>A0AAV4V199_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_580841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013815">
        <property type="protein sequence ID" value="GIY64012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V199"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="14163" checksum="0F66CC00CA6DC236" modified="2024-11-27" version="1">MKIEFECCKKSALCWCIKKSEEKFELLGFEKTMRESSCLRRIDCQRKFLMCQQRDKSMLLSGAEPLLEWIVETGSVLSFRLLMSILPFLQNEGITIGRDKWLYCYSYYSGMHFNTISTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKP5</accession>
    <name>A0AAV4VKP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_684011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014733">
        <property type="protein sequence ID" value="GIY70912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12719" checksum="1DC6CA30DB7334D1" modified="2024-11-27" version="1">MDIGDRPDIAWDSPTGRCKLTLPDSKRMGFAQEYLSACSQLRVFLESGFKSRSPSAALVNYQCTIHWLPGAYLMSSSDKHDITAQVRPEEKTFGSQIFAFKWPIISILLHVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNV0</accession>
    <name>A0AAV4VNV0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adult-specific rigid cuticular protein 15.7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_14101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014816">
        <property type="protein sequence ID" value="GIY71474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY71474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="23359" checksum="62AFF7A87168F469" modified="2024-11-27" version="1">MDVWLTEDTPLPVAYGGVLGHGAAHGLGYGAGIYDCFLLRCFCSCQCLCTLVNTGVSTSSRQQDAFGNYAFGYGIKDGLGATNSRSEVGDGYGNKKGSYTIADIDGRARRVDYVADGHGFRATVKTNEPGTAASAPAAALIASPLRRTRRPSRQPHRPPSCSSCRRRPCSLWSWCSRSWTWSHPWFGIWSWCPQSGHGAALGLGYGAGVYGAGLGKVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPV5</accession>
    <name>A0AAV4VPV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_674341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014922">
        <property type="protein sequence ID" value="GIY72267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY72267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="291" mass="40913" checksum="690300C3E0305F27" modified="2024-11-27" version="1" fragment="single">RERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERERGERHMVSERERERREREREREKREKREERRERERERERERERGERGVERERESGSREKERERERKRRERERRERRERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTR5</accession>
    <name>A0AAV4VTR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_430551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015111">
        <property type="protein sequence ID" value="GIY73631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9174" checksum="BE11C0A29BA143BC" modified="2024-11-27" version="1">MLSNLQDRGLRPLRGQGTPLTSKPRDIRTDKSIATSNLSTHHPRFANPSHIMEHPPVQPTHKYFETSGWKFVNSINIGKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVA1</accession>
    <name>A0AAV4VVA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_334601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015212">
        <property type="protein sequence ID" value="GIY74391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="51" mass="5680" checksum="652C4EAA91AA8D8A" modified="2024-11-27" version="1" fragment="single">FFSAHHLPTEATGKSFSYLSLRVNISVEARRILKAPGMGQKILEECSSSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZL2</accession>
    <name>A0AAV4VZL2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">valine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Vars1</name>
        <name evidence="11" type="ORF">CEXT_528931</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01015382">
        <property type="protein sequence ID" value="GIY75746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000015">
        <property type="entry name" value="Valine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="entry name" value="Valyl-tRNA synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="10">
        <location>
            <begin position="107"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="317"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY75746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="388" mass="43833" checksum="DD7C9246CDED55F8" modified="2024-11-27" version="1">MERPHRALHASLLDSNLDPKEIEKAKQGQKADFPSGIPECGTDALRFALCAYTAQGRDINLDINRVEGYRHFCNKLWNATKFALMYLGTDFKPKAAFQLSGHESRMDLWILSRLSFAVETCNAGFETYDFPAATTACYAFWLYDLCDVYLESLKPVFQSGNELSIETSKEMLYTCLDVGLRLLSPFMPFVTEELFQRLPRRQSNPAISITVAQYPIPEKFSFKNEELEKAVSFALNIIHKIRSLRSDYNLAKNEKLEVFLKCDDEETKTQLSGLHETILTLTSSATIKIANSEEIPQGCAITTISESCEAYLLLKGHIDISKEISRLEQKKEKLSSQISKLKQAAEVPDYESKVPAAVRESHSEKITLSEGELNKLIQAIETLKIMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W178</accession>
    <name>A0AAV4W178_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial chaperone BCS1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">BCS1-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">bcs1l</name>
        <name evidence="17" type="ORF">CEXT_680541</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015426">
        <property type="protein sequence ID" value="GIY76003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W178"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000768">
        <property type="entry name" value="Probable mitochondrial chaperone bcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="16">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="95"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY76003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="243" mass="27681" checksum="4DDE47F98088AED7" modified="2024-11-27" version="1">MGVPWETVTLTALGRNKSLYFHMLDEARKLALKREEGKTIMYTAMGPEWRQFGHPRKRRPISSVILHQGVAERILSDVRDFINTPQWYSERGIPYRRGYLLYGPPGCGKSSFITALAGELEYSICILNLSERGLTDDRLQHLMSVAPQQSIILLEDIDAAFVKREESSATKVAYEGLNRVTFSGLLNMLDGVVSAEARILFMTTNYLERLDAALIRPGRVDVKEYIGHATDYQLKLMYKRFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W275</accession>
    <name>A0AAV4W275_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4817 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_135998_1</name>
        <name evidence="1" type="ORF">CEXT_380911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015464">
        <property type="protein sequence ID" value="GIY76299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W275"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11370" checksum="BD9CC063BFF9C807" modified="2024-11-27" version="1">MCPCALRKMIQKFETTGQLAILLNRERKQIPSARVENGATAVVEASSQSPPGSVSVPVVSHVLVIPYSTKRKIPTTVFEFLSLFKIIPVQLLKDGNPQVSTLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5X0</accession>
    <name>A0AAV4W5X0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_444651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015678">
        <property type="protein sequence ID" value="GIY77783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5X0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12298" checksum="565AE093AE5B7B6F" modified="2024-11-27" version="1">MKISVQWVGRYGVTNDAPAFEECILDCKLLNKVCLVILKSHQKQSFQKIRASSICSSTIGQPLLIRLKGGEDVLDIFLLLRLQDSIVVSFLRHARSDVLPPPTEEYCVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7Y6</accession>
    <name>A0AAV4W7Y6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_616361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015720">
        <property type="protein sequence ID" value="GIY78155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7Y6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14767" checksum="67F635CDCF678A25" modified="2024-11-27" version="1">MGYPTARSSFCVEAVRYVRFSEPGPNYTVMESVFSPTKVEKTTVLFFLVNPSETDGINSTQVETTQPTLLLYSIKPSASHYGVSNRKLFPSRLWLCITCDSLNPTPNPTVMEKCFLSNQNGSKVNDSVDTRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDL8</accession>
    <name>A0AAV4WDL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_16076_1</name>
        <name evidence="1" type="ORF">CEXT_251841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015944">
        <property type="protein sequence ID" value="GIY79909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12543" checksum="26708C733E9E3CAA" modified="2024-11-27" version="1">MTFQITNIASYCKICNSALFHCASNKKKSMHGQCPIGKESWCFYQQAIANGKTIIEKYTGLPNDILNIMKPVYLELWSRDLLQKCLHGKLRMQMKKESFNGTERNFCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WK55</accession>
    <name>A0AAV4WK55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_241271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016361">
        <property type="protein sequence ID" value="GIY83275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WK55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8510" checksum="B5A34F46429C96FD" modified="2024-11-27" version="1">MHTRNPTVDWTSTAFYATLDIHHHLPCYQFMGQNSMDRVHTPALDRRLLVDRPYEEQHRTNFKNLTTRPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVQ1</accession>
    <name>A0AAV4WVQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Dynein intermediate chain 1, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Dnai1_0</name>
        <name evidence="12" type="ORF">CEXT_141351</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016726">
        <property type="protein sequence ID" value="GIY86000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="110"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY86000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17298" checksum="6C8E70D6467A5CAD" modified="2024-11-27" version="1">MPKVTFDNTHNRMKWKTLIRQALDNLFPVDVVTTLRVRDFPINPPPKGLEMHLEPSAKVGENLGLNNLFFFRQYDNSFSEPHDSELFLVGTETGLIHRGSFDDKVCNATYEDHKDKVTFIQWNYLHPRVFLSCSNDYTLQIWDHKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WX82</accession>
    <name>A0AAV4WX82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016744">
        <property type="protein sequence ID" value="GIY86133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WX82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11886" checksum="3A881ED5B07EC08B" modified="2024-11-27" version="1">MHALYSRLIAGDSELRILAYSESNPRGLIHLKRFCHRPVPLRPACLLSGPVQSPTPPLVRSTSTSGSLCLMFTSRTKRSPPRSPATLCPQYEKGTSFFGTHNRFVQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZV9</accession>
    <name>A0AAV4WZV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_579831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016932">
        <property type="protein sequence ID" value="GIY87376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13966" checksum="517B5542985F9079" modified="2024-11-27" version="1">MGVWGMEVPQGNTQKKNRNTLRDTQSDNWEYAKDIKFPLPYPKEDQRLQSGLIAPDMEISAEKVPTLNYQKTNSTSLAWRNECSIELRNIEVTNYENNFQKSEFKGNKLSGKVCDHHCKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2J1</accession>
    <name>A0AAV4X2J1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_61761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017209">
        <property type="protein sequence ID" value="GIY89466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15923" checksum="0A8A36648AA4398E" modified="2024-11-27" version="1">MILYILKDCLALIRLAHVSGFIRMTLQLVEVTMKHLLPDGIVSLMYIPDSEEDFSKTLDPDFRDTGIQWSPSSLFKLSSGRYGSHLNGIVRVCINSVMIIIKGTHYLDRNVQAWIYLRNDIGNSRFYDPPFSVEKDARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4P2</accession>
    <name>A0AAV4X4P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_461601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017235">
        <property type="protein sequence ID" value="GIY89623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11025" checksum="4DB7B1A0E74FDAB4" modified="2024-11-27" version="1">MTRNPLQMWSPVAGEQLCQLCAILDCARTVCWAVASFSTEIVQLSTEITTWESLKNTTPPDGISRASSYFAASCTAHISPYLHKEELKGIRNDPLQISPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X6B4</accession>
    <name>A0AAV4X6B4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_764211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017224">
        <property type="protein sequence ID" value="GIY89551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X6B4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9456" checksum="10D7A5B13F8A57E9" modified="2024-11-27" version="1">MAPPKRSIDAPPDVTEGDRITRNGELRAPPPSTCSADYFRAAASGECGVGFSISGMVHYRTDNSFARAQQMPGFLREARLSRGNVRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCC5</accession>
    <name>A0AAV4XCC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zinc finger protein 710</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Znf710_2</name>
        <name evidence="1" type="ORF">CEXT_668811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017516">
        <property type="protein sequence ID" value="GIY92282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17397" checksum="BADA6AEB5D020EFA" modified="2024-11-27" version="1">MTRKSSIVSRKIKEEREIKKNRVFVVMQDGTMVEINGNDRQKAVMKATAKVEAIRRSVGKIREMEKAKYQEEDEDDYDDLKKPGARYSYSLKKRNDTRPALEDCTLETIEDFSATILPNSVQLIESELPVKEADNLKISWHVSVSSNLFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEL5</accession>
    <name>A0AAV4XEL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000261">
        <property type="protein sequence ID" value="GIY93371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10279" checksum="5CE3C1F1F2123100" modified="2024-11-27" version="1">MNVRKFDTEKGIVFWKIEDARFRKPRVSRFRHVKSIDPLGMLNLPIGSRGGEKDRKLSKINFVTENQGDTIEVALFRRNGKCPWVFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNL1</accession>
    <name>A0AAV4XNL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_523891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017989">
        <property type="protein sequence ID" value="GIY95978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14613" checksum="1AC4B97466082552" modified="2024-11-27" version="1">MKPPVIFLENLRPLPTASRISAGWGRRQTNHVYPLPRKTRRLFIALHYLLTALTPVVENEWSGENKGLEANEILLIQMKGRFQSCGFGPKPCKVCLRKMVEEICGCLASFQTAETLHWRVFVHTYFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP56</accession>
    <name>A0AAV4XP56_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase family 92 protein</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVEN_4566_1</name>
        <name evidence="9" type="ORF">CEXT_745901</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01017937">
        <property type="protein sequence ID" value="GIY95584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF40">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY95584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="438" mass="50065" checksum="8A147B0E1EE6B146" modified="2024-11-27" version="1">MKVISPRHSFSLDYTPKQWVVFCNTILLILVTFMCGMVVYEICDINQKFVTILDSSAIAIDILATNIINSKTTPFWKTINNDVSVYSAYYKATSFDEGLIIIIGSSTKSGVDFKDIRCLIKYADTEDISIMEASYEKFSNCNTLFLRCPSKSDGVPTKVVLISNEDIISKRWIDIEIISRKTDGDIIAPKIAACVQPLDESVSVKQIQEFVTFYEIVGLSHFYFYNNNATQSTVDFIQQLIYNDYPISILPWNKKLESSEKCPALGYEYVQDCLHQALNKYSDVLTVNTADYFVPLKYFSIDKMLLNFNNSYEVLHINKANYCDIHDQKEVVQQSIRKMLFRGPICPSKTNYFLRPEFKAAIEFHGASASASKKIGKFVQDLPENEGIVQHLVRKCDSDVTLDSSAYKYFKKIDKSMIFEAYKQTSRKTVVQIPFPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQ71</accession>
    <name>A0AAV4XQ71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000712">
        <property type="protein sequence ID" value="GIY96879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQ71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9269" checksum="9E3F18B513603A83" modified="2024-11-27" version="1">MNKTKEFSTYPPYITLGSKLNHSEENQDPANAINVKNHHSKFCTRDPRCLKCAGPHATKECTKRPDEAPKCAFCSESILQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUP7</accession>
    <name>A0AAV4XUP7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Monocarboxylate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_552461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018178">
        <property type="protein sequence ID" value="GIY97564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF251">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="19152" checksum="0C9CFE3257A4248C" modified="2024-11-27" version="1">MLLATYFTSIVAGIPERGAGPVPLPLIVAFCRRKSTRLTAVFGGLTAALGCLFTSFASQMHQVFLSYGFVMALGLSLARVTSSLMIGQYFKRRRERVEVIVASGTGCGVIIFSYSFAKIIRVLGWRLGLHAITGLAVIPFFRGHLLSFSLPLPPPEEGHPAPQEPEEEDQGQVRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWI2</accession>
    <name>A0AAV4XWI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_334011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018421">
        <property type="protein sequence ID" value="GIY99431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20061" checksum="ACD301AA985B0D28" modified="2024-11-27" version="1">MRLPFLDLTLPQKEAAAAGENEKKEKRQRERNWSVWGGGRGEQGLLIKAFNEGRHSAPSLKSRFIRVGTGFGEGTGSPQSIIGGGNSVSRPQSVFGFLILNYARKDRFLHLANPATPLPPLIFFPGFSWEKEPLIRGNKGGGLFRRNLKRVLKENEGFSKLKIGKRNKTSVPVWDAFQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXQ8</accession>
    <name>A0AAV4XXQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cilia- and flagella-associated protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CBG09753</name>
        <name evidence="2" type="ORF">CEXT_737741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018472">
        <property type="protein sequence ID" value="GIY99881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="1">
        <location>
            <begin position="27"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="232" mass="27118" checksum="36E6FB0987B6F0F3" modified="2024-11-27" version="1">MVLPIRTMPVDWRRRKYFPRQKSAILRNVIQTGVVTILSSHGYEPLKFWTIHPGNGSILRMRTPDVKGLVLEILAPIFCTTYIAAPEDIRMKMDCTMPLLVLVVEYLEAPFTIEFSVKDSRNMKRKFRLSTCLMSSKLSSLMCHMPLELRKGWNKVEIDLEGLTMLSYNTNYVEFLMIYIYANCRLRKVYFADQEYDESELPVDFNIKKPKIPHKPEENAAFTLYPANLHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZV7</accession>
    <name>A0AAV4XZV7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_118971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001154">
        <property type="protein sequence ID" value="GIZ00438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="8783" checksum="9DCBC54DD6D27881" modified="2024-11-27" version="1">MVFDADSTGDDGRFDSPPSSRGVGGLGVTVVGRFEMSNRYIHIQADRLLGFALKYLGFLGSLTIVGKTSKVAVVYNTVIVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0L5</accession>
    <name>A0AAV4Y0L5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Down syndrome cell adhesion molecule homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dscam</name>
        <name evidence="4" type="ORF">CEXT_127521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001192">
        <property type="protein sequence ID" value="GIZ00678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0L5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000120">
        <property type="entry name" value="Down syndrome cell adhesion molecule like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF6">
        <property type="entry name" value="CONTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00014">
        <property type="entry name" value="FNTYPEIII"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="11"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="112"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ00678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="33176" checksum="4AB140524753E7CF" modified="2024-11-27" version="1">MTLLFAEVPGPPSDVRVEQTWSQSATVRWNVPYGGNSPITFFVVQYWRDAGAVPPHRLEEEKVSASQTFTMLKDLQPGTSYVVRVLAENEVGRGNPSESQQFLTKEAEPSAPPTDVTVESRGAGTLRVKWKTPPREQWNGQLKGYYIGYQVASSSEPYSFKTVEFSKQGEEEYRLTNLQRSTEYRVIVQAFNSAGSGPPSQDIIAKTSDTDPPSPPLPVGGLPVSLEHRTQVETQEPSREEGRRQRDPCGPARTLYTVLQGRVRAVERDHSTPVRRAGVHPERAARGHALPNVHESHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4V2</accession>
    <name>A0AAV4Y4V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_748581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001312">
        <property type="protein sequence ID" value="GIZ01505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10976" checksum="0B4DE9C30CA0AD54" modified="2024-11-27" version="1">MCNLKKNTPGHQLKKKPHSVITKLWFYEYQAQKQCHPIKKKGDHQQIQFGDISFKVLLSLKKILASPQGFSRVRGSVLSNDTSGKEAVLVGKEEKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y571</accession>
    <name>A0AAV4Y571_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_37221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018817">
        <property type="protein sequence ID" value="GIZ02492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y571"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8071" checksum="F0287BB1A7F5BB59" modified="2024-11-27" version="1">MARNLAFPFTTGHKTQLHESNSISISARGTLDKKCLGFIHISIPDRKLLLRVARKGQADAGIITSAVIAAPNFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7Z3</accession>
    <name>A0AAV4Y7Z3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_524751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001558">
        <property type="protein sequence ID" value="GIZ03143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7Z3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24185" checksum="4280EB9B4CFDA0F3" modified="2024-11-27" version="1">MSIAYICLERCVGKRILLCLVPDETQPPRQNRNGHQAFLMDIERQILDANDPDTLASSGSGTDPTVRALGASRQLTPAEKWSIRPPPIGKEWNQSTEDNELEIEPTKLKGQLNQSKEDNELEIEPTKSKGQLNQSKFFKDNELEIEPTKSKGQLNQSKEDNELEIESTKSKRQLNQSKEDNELEIESTKSKRQLNQSKEDKEQEIKAPKSKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8S4</accession>
    <name>A0AAV4Y8S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_514711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001527">
        <property type="protein sequence ID" value="GIZ02939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8301" checksum="044456662FA45477" modified="2024-11-27" version="1" fragment="single">YIQFRRLPLESIPFETHQTIPPSSVQRWLRHLPEADIFLVTKNNIAESEKKCFVLVLSGVGEEVKRNFLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9A2</accession>
    <name>A0AAV4Y9A2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_87803_1</name>
        <name evidence="1" type="ORF">CEXT_164791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001557">
        <property type="protein sequence ID" value="GIZ03134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF233">
        <property type="entry name" value="BACK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="504" mass="58088" checksum="D276D3A0EFBC5977" modified="2024-11-27" version="1">MNIIRVDQNENLQTFCLKCIASNFDRFYSLFNFSDYEELPTTFKVLQKFYSQPLLKLMFDYMLLKNEHLKFLINRYTHELNIGYLINCDSSAIEERLQEIGSVILTFEMTVIKKFNCDNFLRHLSKIQVLQLYDTIFSDKSMVIISKNCTELKSLDIYNCSRVTDKGMETLCSSQPPLEYLNVEHTSVTYKGVSLVLKNIPSLTTLRFDNVPRAIFEATGLNDTSGISNSMVFNLSNLVILNNPMRPENHLTAILNACTVSCPHIQNLFVSEIMTETQMQLISTFQKLKIVSLQCSTIVNPPLCIDNFLQVRGNQLTSLSLTSFSLSVKLLARCCPNLENLSLQYPSFEDVDNFDFSSNTGLSFEYLKMFNLQNVSLEMNKDQISFIISSSPNLQELHVVYCHFSDDIRDIILHYPKKLTLLNFSNTVVSAEFIEEVIKTHNNLDKVFIRNSGISSVEYDDIMDMVDEMGKEINISWADYTEAIRELFYFDDSVFNSKRYILKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAP1</accession>
    <name>A0AAV4YAP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_482051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019064">
        <property type="protein sequence ID" value="GIZ04302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10519" checksum="33D23BE8B1FA912B" modified="2024-11-27" version="1">MQAINYLLSTGMCKHPLFVSAFRNETNIYSRPVPGVKDHTRTHSQIANNWDNYTLPCPSTCCRFYHCADSESGKSRSLYFLSFAFPELMSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCX9</accession>
    <name>A0AAV4YCX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_431811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019006">
        <property type="protein sequence ID" value="GIZ03861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16329" checksum="BB3F4A8438472616" modified="2024-11-27" version="1">MHDPEPTENVSGIFIRKIYPVEIPGNNKLLQDNLHRRLQDCGLILSCLLSLFYLRDVKLGVVLFISLRKRRHNLVDFRIIEDEEIVSNDLASLSFTAIIYNENIYLLKKLSVVGNNNYLAHYNGRNTILITQVYMMSMAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDR3</accession>
    <name>A0AAV4YDR3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="4 11">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">G6PD</name>
        <name evidence="13" type="ORF">CEXT_70751</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:15842"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="4 11"/>
    <dbReference type="EMBL" id="BPLR01019234">
        <property type="protein sequence ID" value="GIZ05190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09276">
        <property type="entry name" value="Rnase_HI_RT_non_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000111">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 11" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="7 11" id="KW-0521">NADP</keyword>
    <keyword evidence="8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="12">
        <location>
            <begin position="75"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIZ05190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="841" mass="96629" checksum="8A49CBCC58215D8D" modified="2024-11-27" version="1" fragment="single">MVNNELQLLDKDENTLKNSLQNYNCSPEHLLTLPIVPRHDPPLCEIFLQKFRFQNKENPVSLIVNDFSDCINRFFSDHYIIATDASKSHVSTLIAGISCNQSFSYRINPINSVFTAEVLAICVAIDELAIVDKDILILSESFSALNSLKNLNIHSTYAIQRLASKLFVRQTFNQNITFLWVPGHSEILWNEKADSLAKNTTELSQFIEWISPEDVIANLKKQSYLILETNYFSSKYYDLIGNFPDIGTITKWTQNRRQDILIARIISRMIVTPALLNRFNLDSNPFCNIYSVKTKVKRISKRTAKLGCVESITSSRSFRVDKGSVSVVEAQSFQTYYQFRANTPNNMDPIASPQSIALLKESILHLDKPIQEESTYVFVILGASGDLAKKKIYPTLWALYRDGLLPPKTKFVGYARTNFKVADIKSRAMEHIQLKKDQELMLDKFFELNYYIQGTYENPDDFEKLNKELDSLEETASANRLFYLALPPTVFSVVTKNLKLKCMSSKGWTRIIIEKPFGRDSQSSFELSQHLSSLFSEEEIYRIDHYLGKEMVQNLMALRFGNRIFGPIWNRDNIASIMISFKEPFGTQGRGGYFDSFGIIRDVMQNHLLQILCLAAMEKPVTTSAEDIRDEKVKVLRSMKVIKLEDVAIGQYVGNPELEGEGKEGYLDDPTVPNDSVTPTYALATCFINNERWDGIPFFLRCGKALNERKAEIRIQFKDVPGDIFNEHCKRNELVIRVQPGEAVYLKLMSKRPGNIASFDLEETELDLSYNSRYKQWEKLTSFPDMTKVPDAYERLILDVFCGSQMHFVRSDELSEAWRIFTPLLHKIEEERIKPVHYKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M490</accession>
    <name>A0AAV4M490_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleic acid dioxygenase ALKBH1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ALKBH1</name>
        <name evidence="7" type="ORF">CEXT_604551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001856">
        <property type="protein sequence ID" value="GIX67183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M490"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035515">
        <property type="term" value="F:oxidative RNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035513">
        <property type="term" value="P:oxidative RNA demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004574">
        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557:SF2">
        <property type="entry name" value="NUCLEIC ACID DIOXYGENASE ALKBH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="6">
        <location>
            <begin position="81"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604574-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX67183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="36059" checksum="524567D9FE9B9E21" modified="2024-11-27" version="1">MSKRDFFKEDFKFYRKERKKPSPNFDKVIDFDSKHHVDSVIRVNENYLKMPSSDTQCLSCEKLGLRNHLTWNLFTLKGLDGFVYIQNPFSVSGQQAWIRNCLEKYPRKPSITNLDIHYSNVDDIWSLKNSSDPEKKNYLNKLCWATLGYHHNWDTKVYNPNCQSNFPHCLEDLSKHVANNLGFSTFKPEAGIINYYFSKSRLSIHNDHSEEDMDAPIISFSFGQTGIFLIGSENKCDKPFAIFLRSGDIIVMSRSCRLSYHAVPCIISENATNRYYDTEINDWLEFHEYIDKCRINISVRQVYKNKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4V3</accession>
    <name>A0AAV4M4V3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BUB3-interacting and GLEBS motif-containing protein ZNF207</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ZNF207</name>
        <name evidence="9" type="ORF">CEXT_709871</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001825">
        <property type="protein sequence ID" value="GIX66855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4V3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20908">
        <property type="entry name" value="SUF4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215:SF0">
        <property type="entry name" value="BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215">
        <property type="entry name" value="ZINC FINGER PROTEIN 207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="8">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="93"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX66855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="390" mass="42203" checksum="A2544AAA04B6499C" modified="2024-11-27" version="1">MGRKKKKPSKPWCWYCNREFDDEKILIQHQKAKHFKCHMCHKKLYTGPGLAIHCMQVHKENIDKVPNALPTRNSIEIEIYGMEGIPEYDIKGHEKQKQGGSKDDADTGDENSNSAPETSKQNRHPPAPNVTTMPPGMMPGIPMPGVMPGMAFGPPMPGHPSMGPIRPMPMGMPPGFMPAGMPMVSIAPAQIMPQPTTMTTTVQAAPKPLFPSAVPQASVSTHMPVGTDFKPLMTAVPRPTFPAYSGSNSPNVSGPVTSVPGSAPMLYNSEHASSPQVNSEPKRTGTVVASSPSSKIVHPDEDISLEEIRSQLPRYQMCQKGNRMAMMAGKMPMHGANPMLMNGMGMMRPAMPMPPGIPGMAVPYTATPTIYSQGPPMRPHMMGQGGPRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M583</accession>
    <name>A0AAV4M583_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_604571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001856">
        <property type="protein sequence ID" value="GIX67189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M583"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14307" checksum="1C087DC2941CC3E2" modified="2024-11-27" version="1">MLLSSSDRIAVFYRISHYRVLGRFSCQVNVAFITIELRLKELEMSVNNLRGWVMKDDLTKEEIVAEVIDDQHSKKNEYFSIDPLCFGYSLKSEQYPVEDVVLEKGHCTSGNLFVDGLIEILVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MA83</accession>
    <name>A0AAV4MA83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermatogenesis-associated protein 5-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SPATA5L1</name>
        <name evidence="5" type="ORF">CEXT_701271</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019577">
        <property type="protein sequence ID" value="GIX69343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MA83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="3">
        <location>
            <begin position="48"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="AAA ATPase AAA+ lid" evidence="4">
        <location>
            <begin position="171"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX69343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="231" mass="25667" checksum="35058F16625A2BC3" modified="2024-11-27" version="1" fragment="single">MAFESKACVLERHRWNAKIKERLQWGIELPLRQPEIFQNVDLDCPRGVLLFGPPGCCKTTLARGLATECNANFFAANPSQIYSSYVGDSEKNIAESFKDYKLRNGTKVEKAILYAKNDVIAIAATNRPDCIDAALFATRSTTLLYIFHLLILEERESILQILTNGMPLQGVDVKNLANKTNNFTGADLKNLCSMAAACALKQDLNGEGITESHFMQVLEHLNPSVSTEQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MK48</accession>
    <name>A0AAV4MK48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_189261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002287">
        <property type="protein sequence ID" value="GIX72170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MK48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9419" checksum="708702D7F2222C34" modified="2024-11-27" version="1">MNIVRHFASNPGPLGPPPLSSPPLRPPLNIAKCETKHRKAVSLIRDRISSCVTGNRGRRLLWGSQENYWEVFRELIPEFERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN38</accession>
    <name>A0AAV4MN38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_19581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019985">
        <property type="protein sequence ID" value="GIX73765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11652" checksum="B45159493F79206A" modified="2024-11-27" version="1">MESQHGEKDENLELSKDQQIIEWRNKVSSTIVKWRWDDCRYKQRHLTAKQKEKPKGAKQPESSKKTACSRSPESHNKKGKKQKTTTDNKKGWQEEKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPK2</accession>
    <name>A0AAV4MPK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cap-specific mRNA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CMTR2</name>
        <name evidence="1" type="ORF">CEXT_40681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020051">
        <property type="protein sequence ID" value="GIX74293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11962" checksum="1FE4544C98B4D753" modified="2024-11-27" version="1">MPLSDYEAELEEVQEMCAEEYLERCHIHRGLFIRRLYSSQKQIATNSYDKHHRNGKILRFQVLGETHENLVKSKSMSWPDTILDIKRRLDVCVPKMKREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVD3</accession>
    <name>A0AAV4MVD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020253">
        <property type="protein sequence ID" value="GIX76450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12589" checksum="A585C4DAE6920389" modified="2024-11-27" version="1">MRASSRYSYDPYWLNASHQRACSRYYYDPYWFKRVIREQVPDTTTILIGSMRVIREHVPVTPTILIGSMRVIREHVPDTTTILIGSMRVISEHVSEIPMILIGSMQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWU9</accession>
    <name>A0AAV4MWU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_322251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020295">
        <property type="protein sequence ID" value="GIX76982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15067" checksum="90FC0092E2CA9838" modified="2024-11-27" version="1">MGHCIHRTVSCRFSCDLKTPKWNFTQENYSFKMCSNRITLSEKDTIGSLLQTRLQSSYCGTKHKNNVFLPLGLARILFGEDHVFLNTKSSPFQKGKSFSLKYDSRRIGFFAISDVLKRVRKRPFSTRDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWY4</accession>
    <name>A0AAV4MWY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbonyl reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Cbr1</name>
        <name evidence="4" type="ORF">CEXT_292412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002664">
        <property type="protein sequence ID" value="GIX76446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004090">
        <property type="term" value="F:carbonyl reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX76446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="24351" checksum="9D6D5537A2A6C0D3" modified="2024-11-27" version="1">MSKRVAVVTGSNKGIGYEIVRELCSKFHGDVFLTARNEDRGRAAVEKLKSEGSHPKFHQLDITDDASIKSLAMFLKQNYARDTTPFAEQAVNTMKVNFSGTLKVCLHLFPLLRSHARHGQEGTHEAKRLGVSSLFHFKDRNKCSYYNPAKKFLEDERADIVVNAVHPGFVITDMTGGKGELTPSQGAEAPVYLALLPPNVESPRGEFVWNDKTVACWTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX71</accession>
    <name>A0AAV4MX71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_607841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002665">
        <property type="protein sequence ID" value="GIX76474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18369" checksum="F9FE585EF402DA85" modified="2024-11-27" version="1">MLSDSEAGPLQDTSSLQEEPRRSYFEFHESTRILDFETKLLRSGLLESSEYVHSAFYDSFETSDHLSSDFKVSSTPTLSDDQSSLLFPSNNLFNSLIQDKSSFSTENGIIYSQILQDHSKVKSEITPILNVPKEIVTSPLLPIVSSDIQKSKKYEHHFWNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY19</accession>
    <name>A0AAV4MY19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_47241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002753">
        <property type="protein sequence ID" value="GIX77422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8639" checksum="1D8BCAC8BB17C6EC" modified="2024-11-27" version="1">MVINSVLSLGEVCTLHELQGCLESLQSVTQNNDLVFVTTRTELLALCRSVAILTIELMVLGQESTYAGMGINNPQVMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYY9</accession>
    <name>A0AAV4MYY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_413381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020355">
        <property type="protein sequence ID" value="GIX77762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23275" checksum="80D411F914CE5E9A" modified="2024-11-27" version="1">MRREAQTELAPFPFRMHAPFFVVLSKGLYKNDVFLGISDSDNYGGWFSLATFIVTWEIRRATLSEVSRLFANAAVFSDAKWLAKHDAQWKETLSSPRPKQQQQRQRVFLIVALSAGNSAKSSSPAAPLPKTPATPEVVVWVGDHLGIFSPSCRRKKNTDIGKHLPPYLNLRINRRHLLGWQATGQKFRGQKPASRHPIRLRSDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N574</accession>
    <name>A0AAV4N574_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_102382</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020472">
        <property type="protein sequence ID" value="GIX79158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N574"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610:SF12">
        <property type="entry name" value="SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12610">
        <property type="entry name" value="SINGLE STRANDED DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04503">
        <property type="entry name" value="SSDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="41"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX79158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="21077" checksum="1BA1B04D119EC048" modified="2024-11-27" version="1">MPPVTGYYPLDSDEAIISNVFQREKEGWVKAENSFHGKNYGGMRPPSGAMGPSGPQMSPMSMPGPGGRPWNPNTSSMNYSSSSPGSHYGGPPVSSSGGQGPGTPIMPSPQGSGPDGMYTMMKPVPGGNMPGFPMGPGPDGPMGGPMGPDMGPPVLNGISSADGMEGMKNSPATGPGTPREDGPQIGDYGIPNYGQDNYQLDPSRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5M8</accession>
    <name>A0AAV4N5M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cyclin-D1-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ccndbp1</name>
        <name evidence="9" type="ORF">CEXT_380611</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCNDBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020435">
        <property type="protein sequence ID" value="GIX78719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049318">
        <property type="entry name" value="GCIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20936">
        <property type="entry name" value="GCIP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="7">
        <location>
            <begin position="50"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like C-terminal" evidence="8">
        <location>
            <begin position="221"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX78719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="350" mass="39102" checksum="BB0B315486C13DE2" modified="2024-11-27" version="1">MASVNRDIPSILECFENSLDLARQQLLENTPERDSANFDLNRFWTNFSGAIKLVSHEATKFCMAFDEEAISSSKACQSLIDKVEKTCIALLAVFTTLPKAKGKVFYKNVHTYTLDILQGMKNLCSAIRNQSSTRLQIVGEIWEKCQAVEQLPSSIFKCDFNFLQSSLDNRDAVLVIFRDQHDMVQDASQELVESLENEDVGPPFELTLVEPLNGLQIPPTEGWSSSDRNVLLPCSGLVKALKACIKKTMQAISERGDGSNEACINELDTIVEIVKSSSSIADDFVLSLYPPMNHSAVREQATLVRNLSKDILSSVKNSHFSTAVDDRWIEFLEKAVDHNWVRISDMALAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N733</accession>
    <name>A0AAV4N733_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_577231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020570">
        <property type="protein sequence ID" value="GIX80115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N733"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12983" checksum="FF0521BB57F1FB05" modified="2024-11-27" version="1">MHKLHLQNIAFGYLWHPPSQIPKRYDKFHPSNHGRLTMHPTQPIARFFTACKSNILPHIQSVPRVYRPCPLQKTDLQLRFSFNRKKSDHSQNSHALTSIIVPRTLSLSVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N919</accession>
    <name>A0AAV4N919_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_507501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003118">
        <property type="protein sequence ID" value="GIX81325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N919"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9233" checksum="F5D9C6774B247FB1" modified="2024-11-27" version="1">MKIDREGKGSSYRSRKSDLLLLGKTKKRTKALTPAISCYTTLDVPNKNCSNYSMKVVLALSRSLLTNVALTRDISVEWCVYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N939</accession>
    <name>A0AAV4N939_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_662311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003119">
        <property type="protein sequence ID" value="GIX81340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N939"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="16967" checksum="B3CC2023F9C0E4E8" modified="2024-11-27" version="1">MLDNSCTNGHFLSFRDNDAVHCHGISIKTRQIFTGCFSSFSIKDHQDVDQNFGVTKQQEKEDEAAAAESNLPNEKRGWAHRGPPPPPLQRERDHQDVDQSIGVTKQQEKEDEAAAAESNLPNEKRGWAHRGPPPPSTHRERERLTIINLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCT7</accession>
    <name>A0AAV4NCT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_15311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020701">
        <property type="protein sequence ID" value="GIX81693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18262" checksum="9C230EDC62BD7E3E" modified="2024-11-27" version="1">MIGFMCIRTAQGWIAALTLIQEFIIIFSLSMFMLVNTLLSLTERSDHKPWFDLLQCVPVAPRSEAVASFRLATRDDSRAKYLFKIGISLTPCCPLIDSKDEMDSQHLFFCPALYPEGVCGRYWQTREWANAEFFSFLCFVLYALCILTAFACHWKNTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGN1</accession>
    <name>A0AAV4NGN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_668751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020917">
        <property type="protein sequence ID" value="GIX83962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13543" checksum="17092E8343006D5F" modified="2024-11-27" version="1">MSPSRHFWNLFNFKSLRHLDLVKRECSVNTESVLFVKKVNFSLQDPFTLRQWPGAKREMFFLGEHLVFSSLLFFCFDLGLDILQGIEESFARCIRQGRHLAQLENVLCIFRRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NL44</accession>
    <name>A0AAV4NL44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_506991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021026">
        <property type="protein sequence ID" value="GIX85084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NL44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14925" checksum="918B02CB7B7F6975" modified="2024-11-27" version="1">MNHNPPPRRLTPRRQNRGARHPDFRARCSPKNISDVLWEEFWKNLEEMVKITPGWNSLYFCSQMQEKAPSFLTRTPFICHRKFYRHPPLKQTPPRYILHFSSRLHTLESRRPFPENTGGKNDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNH3</accession>
    <name>A0AAV4NNH3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit M</fullName>
            <shortName evidence="5">eIF3m</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">eIF3m</name>
        <name evidence="7" type="ORF">CEXT_527611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit M family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021001">
        <property type="protein sequence ID" value="GIX84777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03012">
        <property type="entry name" value="eIF3m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027528">
        <property type="entry name" value="eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040750">
        <property type="entry name" value="eIF3m_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF2">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18005">
        <property type="entry name" value="eIF3m_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="174"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX84777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="378" mass="43044" checksum="11AB3FD8F39547A8" modified="2024-11-27" version="1">MSAPTFNDATDEEQYQDLRSHLKSLGADISEENSEEGYLRDLHDVINASDFCFREANEADAESTLNCIVSLLIMVPPTESEPLVSLFCEKLTRAPSLKMGCVSFKVLQNLFAGIEEKSLLCYDVYFNLVRVAGQTDNVNTVFKDLNKLKSWLFELKVGTEKTQRLLRLLHEVLVETKVMIELLGTYTEDNASQARDDAHKCIVTSLADPNTFLMDHLLLLKPVRFLEGELIHDLLTIFVSEKLSSYVAFYAANKDFVNSLGLSHEQNLQKMRLLTFMQMAETQKEIPFSIIESELQLNSGEVESFIIDVLRTKLVRAKIDELQQRVLVSSTMHRTFGKPQWQLLRESITVWQVNLNKIQSQLQPVLRSTYDNIPNVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPM6</accession>
    <name>A0AAV4NPM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome c oxidase subunit 5B, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Cox5b</name>
        <name evidence="5" type="ORF">CEXT_814141</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021087">
        <property type="protein sequence ID" value="GIX85715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00924">
        <property type="entry name" value="Cyt_c_Oxidase_Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.11.10:FF:000004">
        <property type="entry name" value="Cytochrome c oxidase subunit 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="4">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="4">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="4">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602124-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602124-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX85715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13987" checksum="D3E130FA2B9B7D3C" modified="2024-11-27" version="1">MALMCRNVKNSIRLFRAASVTFRHKSEEKLPHYIEHSTGLERKELLARAAGNDDPFGMNVLKRGAGTKDQPNLIPSFEEKRIIGCICEEDSTYINWMWVHKEEPKRCSCGHWFKLVEAKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P201</accession>
    <name>A0AAV4P201_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_522501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021570">
        <property type="protein sequence ID" value="GIX91267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P201"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8268" checksum="A46E63D327074462" modified="2024-11-27" version="1">MASARSIVAEMERKGPNQRMVTGGSDKLEINSSTRIRDQRSCVMYLWKNPQNFSALCMGKEWKLPLPYSLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5U9</accession>
    <name>A0AAV4P5U9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_350111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004086">
        <property type="protein sequence ID" value="GIX92029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5U9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10682" checksum="24804FC454AEF485" modified="2024-11-27" version="1">MTAEWQTKPEWPMLGMLSVRSLYEAMDSYFSGFSHGEREKTKSISDSNYTAAAIPAREALFEQASQSRTTILAKYKENKYINIETVQYDTLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7W5</accession>
    <name>A0AAV4P7W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 3A24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CYP3A24</name>
        <name evidence="10" type="ORF">CEXT_690971</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004193">
        <property type="protein sequence ID" value="GIX93088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050705">
        <property type="entry name" value="Cytochrome_P450_3A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302:SF15">
        <property type="entry name" value="FATTY-ACID PEROXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX93088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="398" mass="45656" checksum="BDC503D03C0AA156" modified="2024-11-27" version="1">MDQLKSEATPNSVITSWLKEYGRVFGYFIGEIPYIVVNDLDMLKEMSIAKILLSLKLTNTSIDLRYLSGTFHVFTNRPDMFVNMKPLNKTVIHLRDKRWKEVRSFITPTFSSGKIKLMTSIVDKKVDVAVDVVTKKAESNEMFDMYELVQGLTLDVIADCALAMKTHCQENQRIFLYATFRYAHNKAADYAIMFPFVETIMCFVCNYLTAGQMTKLIVDSVKTAVAARRKNPEIKSMDILQMMLDKSDLQYLDQVFSESLRYYPPVTGFVFRKCSEDHRVGSITVPKGATVLAPVWDIHHDPQYWPDPWKFDPDRFSLENKTSINSMAYMPFGIGRRNCVGARFAQLEAKLAIFRLVKKFKFVSCEKTDDPLPLICPTVIINPANGIWLRAIPRDPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PG47</accession>
    <name>A0AAV4PG47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxidasin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pxdn_0</name>
        <name evidence="2" type="ORF">CEXT_160571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004586">
        <property type="protein sequence ID" value="GIX95968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PG47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF134">
        <property type="entry name" value="LD42267P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16219" checksum="CAC421AC88183F9D" modified="2024-11-27" version="1">MCKNPTFGNSNRRFVRFLAPDYADSVSLPRQSSSGEYLPSAREVSMSVHTDSDKPHTHVTFVLAIFGEFVYHDLAHVAQSAGYQGSRIKCCGVEKQQFHPECYPIRVPSSDPVFGRRNQNCMEYTRSSTAPRIGCTLGPESKSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNJ7</accession>
    <name>A0AAV4PNJ7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein HIRA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HIRA</name>
        <name evidence="13" type="ORF">CEXT_4151</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004787">
        <property type="protein sequence ID" value="GIX97490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019015">
        <property type="entry name" value="HIRA_B_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09453">
        <property type="entry name" value="HIRA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9 10" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="66"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="12">
        <location>
            <begin position="723"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="558"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX97490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="791" mass="85779" checksum="4C7C08BF8C7751D2" modified="2024-11-27" version="1">MKLLKPNWISHDGHPIFSVDIHPDGSRFATGGQGADTGRIVIWNMSPIIDESEEKDESVPKLLCQMDNHLACVNCVRWSGSGSGKYLASCGDDKVLMIWQIGSRYGTAGSTTFGSNGKMVNVEHWRCVSTLRGHSGEIIAVLKGHSGLVKGVSWDPVGKYIASQEAVVTEPFLECGGTTHVLRLSWSPDGRYLVSAHAMNNSGPTAQIIERWLESQQGLCRTFFCCCAIGSRDRSLSVWLTYLKRPLVVVHDLFSNSVLDISWSQNGKQLIVCSWDGTVAYIGLSDEEIGKPATDEEKNTLHQSLYGKSMAMTNHSASPALTVVENPDILKFQEELKVREETNFKDEAPNCSSSPLPPTNDIGVSKIELQNSSNSQGSKPSLHIKGPTDKQIETRLADGRRRITPLFIPPPPDIGEVPVPFNSRALPTFSSSSESKSKIVIEKRDESCDASSLHSLPRVENSTSALDSHASVTSSTATVVNSICTTTGATSIKTSVISSTANCLPIVSSSAKQSSVLTNATSKVSQEETGSKLESTTPVVQEQIEDKSKEVLTSTPVFKTKESSIPPKLPSDITPIAVKRKADVQLSGKPEKKKPGRPPLSQSQNQTPKTAPIEKAVVPEKPTTPEKSSHLNSSLHLPVLKADKTTNVLIYHEKTKGTPVYLEIENSISVGSGVVIHRLKCLSGTTLMWEIALNSKGAAVAGSRLISCIVCEDKTLSVFSNNGRRLFPPIVLTSHVTRLTCSDQYVMVITSKGYMSVWDCLKLINLIQNESLYPIMQDDTTGDLSVRGTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTB2</accession>
    <name>A0AAV4PTB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G-protein coupled receptor Mth2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mth2</name>
        <name evidence="8" type="ORF">CEXT_61641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005160">
        <property type="protein sequence ID" value="GIY00289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15039">
        <property type="entry name" value="7tmB3_Methuselah-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053231">
        <property type="entry name" value="GPCR_LN-TM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902:SF4">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902">
        <property type="entry name" value="LATROPHILIN RECEPTOR-LIKE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831342" evidence="6">
        <location>
            <begin position="23"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="118"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY00289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="437" mass="49314" checksum="116BFE919AC09D2D" modified="2024-11-27" version="1">MNKIIPYVTFILTSLNVACINASNDTYAKDNMTDPGSNFIPEEDIYANKDESLQTCFGFNISSEAYLIFPNGTAYIPIYNKTYEEPFYILDGEFLIVCAPPEIFEEEEPVSNLVSTSLRYISVVGTGVSLVFFLVHLVVFALVPDLHNLPGFNLASLCLSLFISYLILFLSDVGALDETGDACVAKASSVQFFLLASFVWMFVMAFDVFRSILSATESFRAAVKGFKVKKYILNSCICWGTSLVFTAAALIADNVEGIDDIYKPYFRENTCWFKSKQALLVFFAGPVFTLICLNVLLFAISAYIIFANRMKVGEENSKRAYLKKNYHTYLRLAVIMGVTWITGVLAPLVNVLWLWYLFAILNTFQGFFIFIAFTCTGKVKKYFRMNLENVRRASQQTLTTPTFQSYCNYANSIEKDLDKVVDKKEKSGQIDTIVIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PX38</accession>
    <name>A0AAV4PX38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_158831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005350">
        <property type="protein sequence ID" value="GIY01639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PX38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10833" checksum="06DDDB4627F52BE5" modified="2024-11-27" version="1">MEELAYTLPTPSKLNTSRSFWRKDLATAREYLKQVYQYQDALKGGYCTISNFFVSQFNKNTPAEYSNLGYTLFRKPVKGFSDLTDTFSTCEVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0J4</accession>
    <name>A0AAV4Q0J4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_647941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005334">
        <property type="protein sequence ID" value="GIY01550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0J4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9717" checksum="083B8B4E957832BC" modified="2024-11-27" version="1">MESEKKGEKIHVPRERIPGKSEKILISFFTLQFPQRNTSIQHKSHRMTPSSSPLQNKERKVAKLDTAVDFPVSRKCEKRISKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0Q1</accession>
    <name>A0AAV4Q0Q1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_553701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005484">
        <property type="protein sequence ID" value="GIY02701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0Q1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9625" checksum="68696502B9418C21" modified="2024-11-27" version="1">MFSCYLHSMVPNVSAFNAHKTNAIKRHSLTGCLNAAGYGKHPPKIDPYREFAGAGRAFAGGADSGWGEARGTPLKPVSSNLTRSGTNWFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2M7</accession>
    <name>A0AAV4Q2M7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MSH6</name>
        <name evidence="5" type="ORF">CEXT_744411</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005493">
        <property type="protein sequence ID" value="GIY02744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2M7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair protein MutS connector" evidence="3">
        <location>
            <begin position="99"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="4">
        <location>
            <begin position="293"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY02744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="447" mass="51021" checksum="E9E999CB5660B006" modified="2024-11-27" version="1">MDAAIGVKELGLIYMKGDFAHSGFPEIAFGRYSECLIEKGYKVARVEQTETPQMMEERCKKMRYSTKYDKVVAREICQITSKGTRTLTYQDESMGISNNFLFAICEEHIEEAASSSKYGICFIDTSIGKFTLGQFIDDRHGSKLLTLVALYPPVEILYDKMSITKKTLQLLNHHLTGASKEALSSQFWQPTKVMKFLEDSKIFSKEDNSLEYPETLKKMLDPDDRLMETPLKDYELAFRSLGACLWYLKQCCIEDCLLSMKLFEEYIPLDEVQKELVKSSSDFNKHMVLDGVTLQNLEIVPLLSSDNSEGTLLGTMDYCSTSFGKRMFRNWLCSPLCNPDMISNRLDAIDDLVQIPEVVEATVTLFKKIPDLERLLSKIHAYGLSRSQDHPESRAIFYEADIYNKRKINDFLSTLEGFKQASEIVSLFKPHLNSLSLSFCNLAIIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5X8</accession>
    <name>A0AAV4Q5X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_400261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005763">
        <property type="protein sequence ID" value="GIY04860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10866" checksum="DCFA26747879F104" modified="2024-11-27" version="1">MPPFCDLAHLCTSSSPTPTPACPRESIQNNMTPLSESRGGKIDRWLPSFATLRRQLHLRNGFPFFPLRNRAAEPGAAAPNANPELEPAGVWLLFQRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGG3</accession>
    <name>A0AAV4QGG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_124872_1</name>
        <name evidence="2" type="ORF">CEXT_691141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006239">
        <property type="protein sequence ID" value="GIY08392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12370" checksum="EF23D6C387E1CFB2" modified="2024-11-27" version="1">MMIEVTVLALSRAIITLFAVSFTAGDVHKESKACLGKLDTILRKKDPIRDIAVCQEVQLAFTIFSFFPVHLTVWKFSSLNKAFLMTCIGMMTTYIIICIQLNPNALKSLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQ50</accession>
    <name>A0AAV4QQ50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_49951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006493">
        <property type="protein sequence ID" value="GIY10211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQ50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="17061" checksum="AE848AB606751844" modified="2024-11-27" version="1">MFSLKWPGDLSPTVQSQCSNFRNQFSEDVAWRTNKAIQHPIPIVIACAITSVICWPCSLIEKYRWHQRPLSASWWHGHKPRLTTQKKDFGHSYWRLLPFRPSLDTRCSPIGHREWNAFIEQCSIHNCISSSTSPIVMHLPELEFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTT4</accession>
    <name>A0AAV4QTT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_125041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006601">
        <property type="protein sequence ID" value="GIY11058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10313" checksum="10D212952ED9512D" modified="2024-11-27" version="1" fragment="single">EQPSITQIIFSHYRFEIQLVCPEIFFIDRDRRHKFIDHKALSVGDQARQKQFVSIIWMHALASESPQSQQESFPTHRFIVPILGFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3J3</accession>
    <name>A0AAV4R3J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rap guanine nucleotide exchange factor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RAPGEF4</name>
        <name evidence="5" type="ORF">CEXT_279501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007176">
        <property type="protein sequence ID" value="GIY14987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF327">
        <property type="entry name" value="EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CAMP, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-associating" evidence="4">
        <location>
            <begin position="139"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="243"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY14987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="431" mass="49965" checksum="1F18E14A79A5F93C" modified="2024-11-27" version="1">MLEHLLETRIDQETMIRQIHATNCRQETEFIVANKKRVLQFVQIWATIIRSAFFEDECIAAFLQELHEAVVEDCKKYGLHEELSIISRILETKQKYEKEIAGVPYRWKVGPYGQIRLLSVSESQEEERTEFRRCIKSTDEVVFRVYCADHTYTTIKTPVGATAEVIKRSAAEKLGFKDDLLLVEVKSTAERVIFKDSEVSVPTGLSVNGRIFLTPADEVDLLTPLPEQDGPSDGTGVILETLNSLDIAYNMTIYEWDLFSCVHEYELIYQVFGRHQFRKIMSNLDVFLRRFNEIQHWVVTEMVLCNNLSRRVALLRKFIKIAAQEYQNMNSFFAIVLGLSNIAVSRMSQTWEKLPSKLKRTFADFEALIDPSRNHRRYRLTVAKMVPPIIPFMPLLLKDMTFSHEGNKTYMEGLLNFEKNGEHYTCTALHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5J0</accession>
    <name>A0AAV4R5J0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Homeobox protein XENK-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_587661</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NK-2 homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007240">
        <property type="protein sequence ID" value="GIY15492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5J0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000101">
        <property type="entry name" value="NK2 homeobox 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF82">
        <property type="entry name" value="HOMEOBOX PROTEIN VND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="124"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="126"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="56"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY15492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="255" mass="28656" checksum="B0DDB2F79A16B225" modified="2024-11-27" version="1">MFAFNLQLEAITNLASGNDVHNGSSPRLLSSSNPTSQSSLLASHLSCKVPMSLVDPTSSEALSSTGMENLEQYSSSSEESIDICSRAMEKDSMTSPDMQATSGKLSNSESDKGEESSGQDNLPQKKRKRRVLFSKAQTFELERRFRQQRYLSAPEREHLASIIRLTPTQVKIWFQNHRYKCKRARQEKGLDLKPPAFPTSSCCTSISARWQTMPACHEWLGGETPRLYWTTVSSQRFAFHSIYNVHDIFGGGWGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7J6</accession>
    <name>A0AAV4R7J6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_777541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007564">
        <property type="protein sequence ID" value="GIY17923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7J6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9561" checksum="DE2D3069CEE232EA" modified="2024-11-27" version="1">MIDGSECGIVSHLQLIFGSLHYRETSGKFRNLSQSSVFQVFGRQEEKMPLQDLFGKWYCNARLFMKRLPIVILWLREFFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R968</accession>
    <name>A0AAV4R968_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_802411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007592">
        <property type="protein sequence ID" value="GIY18255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R968"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="61" mass="7143" checksum="B42E5F8A6D408BAF" modified="2024-11-27" version="1" fragment="single">DLADSRRLAVAAFRLNCLHGIYLHLTSFHPNCVLCRRDTVMDALHLKECPEVFGHLYDRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RIK8</accession>
    <name>A0AAV4RIK8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TNRC18/BAHCC1-like SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_63272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007800">
        <property type="protein sequence ID" value="GIY19848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052429">
        <property type="entry name" value="BAH_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056841">
        <property type="entry name" value="TNRC18_BAHCC1-like_SH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12505">
        <property type="entry name" value="PHD FINGER TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12505:SF24">
        <property type="entry name" value="PROTEIN WINGED EYE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24912">
        <property type="entry name" value="SH3_TNRC18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNRC18/BAHCC1-like SH3" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="901"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1324"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1352"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1365"/>
            <end position="1375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY19848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1375" mass="154592" checksum="507653561F27C3B2" modified="2024-11-27" version="1">MPKHESTSFPYFGTLYNNSLPPTAYRLQPGCMPNLGQFWPPTPPPDGCGRFDGSNLYFGPPVLRHAENISSNIRSSFPSLGHYSHLVETSKQNQRLFKRETPISPNVSAPSISICSSGSKSDNLNSCCAVDSKMSQISIAHSLPKPELLTVSSGHEPYLCAPDIRSSSSIHPSTDKSCFSPSHSLKNNLNFHNSSQDNIHRTKTMPGNQENCNASPLKNVYFSHYESENINSVHSKNFEKHSERQPQFEHKNNSFTNGNKSKHFFPSPNNYNQGTFSSKKHDYQNGHEFHNGTSSSNAIRGDKDGVMLIKEHYKQKSSSYKVKPEKSTHSDCKYQKNISKTSVLVQGPEYKNSDMFNIPTSVLHPKIEPSDKYFLSSCSSTAPSCMASYTTSGPFLMDKDISSDLRPSISYQNSIYRNSCSLNKPWHYNELPAINLNNCFQSPEAAKPPSQNPLRVNSALHEGLISVAQTAPQDIEVVKVAGTLQSNVQHVSFPVRCKTVEADDEVQIIGIQTKNSPVKHESQYSLERKSTFHPPDSFTEPLCLKQTKREPEIDFQKNESFSPELKKRKASPSLNCESIISNEERNLHLIPENLKHNEKIASNFEDSSPKVFHKSVSPCKTISIKQELLNESESQSFSCAEEKKTDTISKNSDTLNNSHEKIGDNLKAHLLNEKERIVVKVEEVIQDQEMYNENHGLNMLLNGIEKVTSFEKTSCTFNNSIPEEASKNNCSQNEPVNTFNSFKEMNNVRGLDLLSVIAGQRLVSEFDIVKIEIEETDLSCNYPEVKESKSSEEDQEKQVCEMSKQSSKASVFEIQNRLVELRKRYKQKQKELSRLKPKKKEHVLYCSAYNPPPSCITVRKKRFANSYLKGHQKTFDVSDQSSVSAGSCTTSENLNSSICSTNSEQEVVKPTDVNESSSSSKSKNDSQDIVVDSKIKRSSRISIKREFSKRNLILNRRITRRNFGKLKSSDNILEISEESKRIRRNSVNKFYNKRRSSESVTNSLSGVSARLNKSSRKSSSLPENRKSTKVYSLRHSSQKLNKKTESSEIVALVSKTISSKRKSDNPKKYIPSKTSKLSETIIAKQLRSRILFDTSGSTSDDDSLKDGVPDDLYVAMMKCHLGDENKCGSKLLKNVDASKTTVEGPLGDPEPARLSTEHLVDRQRLLALEDGLFYAGFIKECQAPKKYGIALDGQRGNRLHIFTREELLTQAIVESKPFTPELPEGTRPCPSADWSEPRVFVLFDDGDSGQIPTKNVRLIPEDIIPIENISRADPMNSLRSCYNRQRTSGRGKSRKLKCSNLKCSNMKYSACLVLESVTVASWARNKESTPKRRTPSPQSNSKVDSTEAKEAKIKRHKKYKDKHQAPPPPSSHHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMR6</accession>
    <name>A0AAV4RMR6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metalloendopeptidase</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hcea</name>
        <name evidence="6" type="ORF">CEXT_32321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3 4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01008226">
        <property type="protein sequence ID" value="GIY23014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF883">
        <property type="entry name" value="ZINC METALLOPROTEINASE NAS-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="5">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY23014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16976" checksum="DCE2AE234E9E9AD0" modified="2024-11-27" version="1">MITILNIFRCWSFWGQLGNGEQKLSLGNGCEYMGTIVHELLHALGFEHEHNRSDRDDYLTINWENVEKQWYYAFQKLRPNENRLLTPFDYNSIMLYGEEAFTKQWGLKTMVPKNGQFLPGNYAKPGMTQSDIKRLNMLYNCPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3C0</accession>
    <name>A0AAV4S3C0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_4191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008911">
        <property type="protein sequence ID" value="GIY28150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3C0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043999930" evidence="1">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12299" checksum="1F901C2DD671F79E" modified="2024-11-27" version="1">MLTNCQSKILVHMLPLTFAVTSSNITVRNAHVQDDNRGAVTEPFGDEKLVRTRRSKYAVNCNKTLLRQRQWDWWEDWEGFDVQRRFVYKQCSRKSGVLHSKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7U1</accession>
    <name>A0AAV4S7U1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gamma-tubulin complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TUBGCP2</name>
        <name evidence="8" type="ORF">CEXT_128401</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009215">
        <property type="protein sequence ID" value="GIY30343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7U1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1900:FF:000037">
        <property type="entry name" value="Gamma-tubulin complex component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="7">
        <location>
            <begin position="207"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="6">
        <location>
            <begin position="367"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY30343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="727" mass="84359" checksum="78673A63B1597238" modified="2024-11-27" version="1">MQKYEEIKIKQIREVDPFVSFLYKVQNDDKVKNLLVKETTAKVNGSAILIEKSNLSLNNQLPYKDVKLQKQVSSEEDVRPVPPGIYALPGWVKGRKNISWNFADVTLPDFIHCGPIGALPPNVQECRLIDDILFCLVGIDGDYIYSKKVEKEKVFLVDDTANIALKLLIQNMMPLFSHYSTIIDFVERNIHYERGLVNHALAAAMRKCFGGSVLSVLHENTASLTGSSNSREICHSLTRAASLPYFEILEKWIYKGIISDYYSEFLVEDNELIKKEDLPTEYSDAYWEKRYTIRSQIPIFLSKTADMILRTGKYLNVIRQCGKPVNCPEAKAIVYTMRESQYVEYIKPAYDFASKKLLAVLMDDADLKRRLLSVKHYFLLDQGDFIVQFMDMAEEELQKDIDDIMPSRLESLLELALRTSVVNEDKYKDDVRVELLPYDLLTQMFKILQIPTDMQNEYRNTETMMLTGLEAFVFDYEVKWPLSLVINGKALAYYQILFRHLFYCKHIERLLGHVWSLNKRTKSFPRSEICHYASAFALRQRMFNFIQNLDYYLTLEVIEPHWNDFFGKISQVCNSCILVTNVDEVLFCHNDFLEKCVGDCMLTNPRLFQVLATLMTLCADFSIFLQGIMKCSIDMETSVMGDSMLFSIQEQPFSDMANCPAALENFQLQIASFEKKFDESIICMLHILHSVHQSKQTSKIINMLYRLDFSRFYEEISLKKMENEDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SD14</accession>
    <name>A0AAV4SD14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleolar pre-ribosomal-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">URB1</name>
        <name evidence="1" type="ORF">CEXT_688261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009283">
        <property type="protein sequence ID" value="GIY30834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SD14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="829" mass="94673" checksum="F955AE5EAFADBE65" modified="2024-11-27" version="1">MIRHLALSCFCPIGNIVFNILLPTFAEELLTLIDVLKIYKALANELHKEFDLDLLQMLNDLKICNIHVSRSDLSKIYITLMDLLSEQYSVSLWKKHQPSESPLMLVFRSVESNETDENEIICLQPDEKQKFSNFTAAVFDCLLSLEENKKKSVQMFVQKSIRHLMHHQYSARSFLAAVENYRTLIDPDLFAYWQFLTLSSDIKICIENTCTGNSLCSLDFSEHLRQNFISSHSKLSNPSHILKSKTTLKDGTDDAIISTYIKLLDKLLSSLPILATKDVMDIDCNDEVIKVENDSISPTMPVVEIVKDFLNHPIVLKLFLFYTKNSEKGSNCLSIAVVTATKLVLDVVQKVLSSANEKLYPSFSPFKKKVFKYLQKHRKHDNEDSIQLISIIGTFSPLFSINDVQILLENLLNVKNDSISDLDSYFTTLCLLLQTFLERKELILLSSNCINSLIVAFVSMSKKKKKLFRQYILQLLQQHPIYALLVTEDSSLLLLQAKCVKDLPILGEMIDHNDKFRQVAQAFISDKLHQSDSIEFLYIVSKCLCNSSKENEQDNCFKDVISSNFLASFEKLVLQEISADMDILPECAVGKALQLLLKEKFSSPKKLLHFCKHILKESDNIIPSPEKMLVVLQAFESWKFYSLETNKVRLQILKICCLWLSSGLSNTHKIFELTSFIKEILMSMNDSEIDSVEDIFGQDFFSNALKFALKSEDNGKDILEVLCLLCEKSKGENLPVLSIYGLLTGHSRFFELMLSEEKEKSGLKERLIDLLIILTKLDSSVCKENHVGLILSAYSASMTTVDQKLLYLLKVYADNNIDMSQYSPFLWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFT6</accession>
    <name>A0AAV4SFT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_91141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009428">
        <property type="protein sequence ID" value="GIY31854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043539936" evidence="2">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY31854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12214" checksum="0DE8D53D35EE058E" modified="2024-11-27" version="1">MNSFGITLCVALLVLGVTSALPNQLMSSLKDMPDLTQAGEHDDGPESQRRWAWRSVRTSCTCVRQPPTAARRKTENGTAAQESAATSWDSSGIAAPHSHPNASGGVAGLNSRVVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SG19</accession>
    <name>A0AAV4SG19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_356251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009377">
        <property type="protein sequence ID" value="GIY31422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SG19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14139" checksum="325016CAB9D437C4" modified="2024-11-27" version="1" fragment="single">TSVKTVADFRNRKAFASRKQYLRRNTPKGVLVFRSPPLPEGYCNYEPKLKLSRKMKYETASIPPFTKFPHLPPVTKWRPSSLETEPRENDQADDSSSKRPKPSSPIDIPKRRRRPNGKICEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SG69</accession>
    <name>A0AAV4SG69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_88827_1</name>
        <name evidence="1" type="ORF">CEXT_692101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009386">
        <property type="protein sequence ID" value="GIY31467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SG69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10345" checksum="C1DAE1F147277AEB" modified="2024-11-27" version="1">MRFLLMDRGCWSFIEPKLEETSTRRERSEYKQRQDRAFSAIYYGMDDQHKTLLSSLKDAVEAWKLLQEQLEPKSRASVIGRVFSNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIL6</accession>
    <name>A0AAV4SIL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_364181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009584">
        <property type="protein sequence ID" value="GIY33031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11412" checksum="0498DE91D72443CA" modified="2024-11-27" version="1">MDFNKVNDKKNIEFNKESDKKNTEFNTENEKNNIESNIEFNKENDKKNIQLNIELNMENDKKNIEFNKQDDKKNMEFNKEYARKNVESNEDNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ST96</accession>
    <name>A0AAV4ST96_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Metalloendopeptidase</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hcea</name>
        <name evidence="11" type="ORF">CEXT_486591</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="BPLR01010020">
        <property type="protein sequence ID" value="GIY36219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ST96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="10">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY36219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18827" checksum="0C35DD225D0121DC" modified="2024-11-27" version="1">MNAIKQYHDSTCITFVERTIEKHYVVFKQGKGCYTTLGCVYQGLQTLSLGRGCEPEGTVVHELGHVLGCRHEQSRSDRDSFITVYENNIIPAMLGQFNKTEEDEEILDTAYNTESIMHYGNYAFSKDPDNLKSMEALDGTPLLEPYEKPGLTQSDIDMINKLYKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T395</accession>
    <name>A0AAV4T395_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_796161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010432">
        <property type="protein sequence ID" value="GIY39230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T395"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12412" checksum="90BDA40DE39C632A" modified="2024-11-27" version="1">MLQRFYNSISHHFCLRHARHDKRQLFPTHKMYIFVSLSLTTLKITHSLITLNSKLRADYNWLTQSTTISYMRLNLFTQQSEQCDSSPSAIYATVKEPRMIDIFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T696</accession>
    <name>A0AAV4T696_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_802101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010764">
        <property type="protein sequence ID" value="GIY41820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T696"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="17094" checksum="6B869CAC1425B5D5" modified="2024-11-27" version="1">MDENLRRIHQYVEHITEELEKTILLASNVFCHLEQAVYRLTANDPAGLTADEYRARERQTAILINRLQEHRKVIKHLMEFYDVTMSEVENSNHPTLLHRLEKDIKWKIRDLLYKVLYKELLVDIYQVKLELRQNMSNFARSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9X7</accession>
    <name>A0AAV4T9X7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_79661_1</name>
        <name evidence="1" type="ORF">CEXT_253211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010915">
        <property type="protein sequence ID" value="GIY42994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9X7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="11060" checksum="1DC38FDE4A3B6265" modified="2024-11-27" version="1">MNRVERIRAREIPSDLTEASNSRRKYTLPKLQFRQFGDDLKDWLESWSQFQHIDKDEEIPPEAKFQYLIQATIVGSRAREVVESFSPTRANYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9Y9</accession>
    <name>A0AAV4T9Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">G_PROTEIN_RECEP_F1_2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">AVEN_238977_1</name>
        <name evidence="12" type="ORF">CEXT_150211</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010926">
        <property type="protein sequence ID" value="GIY43080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24243:SF233">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="57"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="164"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY43080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="22064" checksum="14D79CB9DDAD9D86" modified="2024-11-27" version="1">MVGCGSSEFLFLPPASVSQFRGSADSERIQTARPCPTWSRRRPTAPCSPSWPSVSSATTPSAHPLKAGYTCTQMRALAIIAVVWLVASLLTTPVFLTVHYRMAETRATGVLVPVCVLGVEELWQKLYYLAAVGLFYALPFAVLLVVYGHIARHLMAGSRMLASSSEGDDDARQEAGGPHAGRSHGQLLRLPAALQDPHRVADPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TB65</accession>
    <name>A0AAV4TB65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_170312_1</name>
        <name evidence="3" type="ORF">CEXT_770991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010849">
        <property type="protein sequence ID" value="GIY42444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TB65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF28">
        <property type="entry name" value="NANCHUNG, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY42444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="276" mass="32110" checksum="72F7F8CF44A7B783" modified="2024-11-27" version="1">MFLQIYFHILKLQREIYWELGNITCAAYPLDDIDTIDSNTGEINKLSVLNLVVYGEKIDHLDMLSGLLADLLNAKWNKFVKFRFFRQFATFFVYFAISLSCFVMRPGPMGLKVNKHHVNHAIHHPHTTTKSPVQLTNASHFNPCYLLEENSTSHQIRFILEALTAAGALIYILDAVREAQFLGYHTFTQNMVITKNYLFISHFMMENSEILQEINDRTIKSVIHVFLLHYDDNDSFKIHVFSSREDISAVFVMLTTAPYFLFFCRTYVFTVRLVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDL7</accession>
    <name>A0AAV4TDL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosolic endo-beta-N-acetylglucosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">engase</name>
        <name evidence="2" type="ORF">CEXT_253201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010915">
        <property type="protein sequence ID" value="GIY42992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033925">
        <property type="term" value="F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06547">
        <property type="entry name" value="GH85_ENGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032979">
        <property type="entry name" value="ENGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005201">
        <property type="entry name" value="TIM_ENGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246:SF1">
        <property type="entry name" value="CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246">
        <property type="entry name" value="ENDO BETA N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03644">
        <property type="entry name" value="Glyco_hydro_85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosolic endo-beta-N-acetylglucosaminidase TIM barrel" evidence="1">
        <location>
            <begin position="156"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="737" mass="84138" checksum="2D824165F3648EAD" modified="2024-11-27" version="1">MTRLETSELHIYMCCSVAKLIQEINSCQLIIKRLIENEAHTAFIDITASNVINVELKVNDVLIDRRKILNLFLKENIILLEKQSLHEILKKFLEEEKQYAVDYNYFLDECLPIKTLENLANWKPPPTKHVTAPLSKRKKDLNLIKTLICHDMKGGYLEDRFINGAKQDDPFFFVHWAAVDIFGYFSHNLVSIPPCSWISAAHRNGVQVIGTFISEWDEGVKVFETAFSNKILVDQLCMQLVNIAAHYNFDGWLINIENEVEPCQIVLLNHFVKSLTSKMHAYIPGSQVIWYDSVLKNGDLEWQNCLNESNRAFFLNADGIFLDYKWKEKQLIHSYLQAAGRNVDVYVGIDIFGRGDCFTKGGFMTDICLKEIRKHDFIDCRIFAPGWVYECLELKEFKENQFKFWGILQEVIPPRITEGLPYCSSFCPGFGNKMYRNGKIVSNDPWINLNLQQPQPIYYPTAVNCISLYTDDAFNGGGCLCLSGDAIDDKALLEFNILKTSFCLESSCVISYTFKPLTQNTDIALHLDMSSDQGAYKIGLVSTDCKNKEDTNTSVKYLLPATMDDILKAGYKLSPSSEQQTWIREISFINPLGNQTYVLNSIDFRNHTIENISVILSGKILSAKLFTVLFGELEILPVYPVHNLTCEKLICKKSSVKSKTVDIECTLKWQYNSSVFCSDIYIQSTKEAKQYVCTTNQFYYNLKCSVNLTDEIEVILCPKSAGSENLEASLIKIPIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFD5</accession>
    <name>A0AAV4TFD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_366031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011257">
        <property type="protein sequence ID" value="GIY45298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8561" checksum="87BD7EE2A6BE0838" modified="2024-11-27" version="1">MSFRCVRKEILSIRSSCGQRVDGPEPCPRAQPSQQEYVNLIRKIQRSTASAGERKLTLKWRSLWSSKTGVKPGGPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGE4</accession>
    <name>A0AAV4TGE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_394501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010922">
        <property type="protein sequence ID" value="GIY43053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8410" checksum="654091E8C1082219" modified="2024-11-27" version="1">MLGGTTVRPFPTSERPNEQLFSERPITNFTRLHSLELEGNRAASCVCSIPPSSARKSHAAEAKDLVRKSATEGREKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TT89</accession>
    <name>A0AAV4TT89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_53871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011739">
        <property type="protein sequence ID" value="GIY48641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TT89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13143" checksum="C6F54790A9FEAC2D" modified="2024-11-27" version="1">MHDLKSNTFKDHQIVYSTTPIGIKHEIEGCSILFYSTELQTKTRKIRTERGLVFAGSPSAPPPPRADPVGFLLQKRAHSSFITNVRIVILPLIGWRMHFHVVCSSSPEWISKRTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TY44</accession>
    <name>A0AAV4TY44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_28591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012048">
        <property type="protein sequence ID" value="GIY50924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TY44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10972" checksum="0219366B2B86EBBF" modified="2024-11-27" version="1">MPRCIIIALVHSEWSKENNFLCFHSQDNGFHFVPEVSSRDRPPVLVLAMDHCNSKCHSVNRPEIARPLAHQLGMGGRSISVEGVLGIGTSFRPTRKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZD6</accession>
    <name>A0AAV4TZD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167223_1</name>
        <name evidence="1" type="ORF">CEXT_188201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012010">
        <property type="protein sequence ID" value="GIY50687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="512" mass="59198" checksum="51A4932DC6A1C503" modified="2024-11-27" version="1">MFHCAQFLSPKPLGFNACELEDTMAKTKSPNSLYQLCLKETAFLLIEKYWNRENTNPFSQINCNIVNDLFKFLLIDMDIEKPSPLKLLLKSGQLQNLVLYGHIFTEKQWRSVMKNLLEEGDSCRNITNILLPKSFQNDDKASLERLIEKCPLLEMLEVWTFFNPSVLQNCKRLKEVTNEFSGKKEYGYVRNEPVDALAHLQNLKKFSIFQSRKSSSYYLLIAKMLQNHPKLVSLGYTDSSWAAHHIYTTCKMGTVPRFGLKECFWGLNHYVNRFNRRKQIAYTQQYSEFVKSSVALFPLVEKLNIVVYHKNCIEHLKKLRHLCVLNINFNLCRGSPTRTAFISLLSEIGPQLKCLSIMVRSTMPVDVIMKYCPNVVHLDLCCIAVVQGGIKADSKTFRQLKRLRAVVVDEESLKYLLRYSVNLKELLLHDAICLDDTLLHKILKMKSLSKIDTLAVWECRLSREGLKELIQKCVNLENVAFKNLKADLTTVAEELKRDITAPFSYLERILAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1I0</accession>
    <name>A0AAV4U1I0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_733581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012136">
        <property type="protein sequence ID" value="GIY51648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1I0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8829" checksum="41C74E41F66944D1" modified="2024-11-27" version="1">MLFERAVVNSSVSPKQKLGNLIWWKRDLRLGSADRNKNTGLIEGVCFEDTNPNPIGAITALLKGGCVTKQAYWFSVQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U341</accession>
    <name>A0AAV4U341_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_174881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012206">
        <property type="protein sequence ID" value="GIY52181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U341"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="15343" checksum="A1C704F9FBA32084" modified="2024-11-27" version="1">MRLPNQSLSINGLDFHNLVYFVTCVQQKKTRTKRHKKSRLSRHVFLFPFQNSPPNGIFVGRILFRSIYFEYELNEICIVFQRTSRERARGNGIFPFPTSLRFGKYFLLLSTLHSEVFDSSRNNEKDFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U956</accession>
    <name>A0AAV4U956_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_199511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012496">
        <property type="protein sequence ID" value="GIY54314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U956"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12028" checksum="BC9261F1B1CA3111" modified="2024-11-27" version="1">MCCPTLKINHISPVLHMYTNLGERASCSVSSSDYGYVKQRQQHDVQYNVVLFTVWLPRVFLWMHYALRFLLGVIHSERYKSRLPLSPAVKWKWSSEILLFPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V081</accession>
    <name>A0AAV4V081_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5-aminolevulinate synthase, erythroid-specific, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">alas2</name>
        <name evidence="6" type="ORF">CEXT_88191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013738">
        <property type="protein sequence ID" value="GIY63433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V081"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048821">
        <property type="term" value="P:erythrocyte development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042541">
        <property type="term" value="P:hemoglobin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="129"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY63433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="282" mass="31483" checksum="1D3182FF8E6965D6" modified="2024-11-27" version="1">MANSSFFVTAGGVRQITNLSVRSCPFISSLNPKFLQNYGKSIRKLYADQCPFLRHYASSIKKPENAEMIPDIKCPFLKQVKPSVKAASVEIEDDIIDLTSEKNNRIFKKVNRMADNFPCANEYSNGEKKVLIWCSNDYLGMSSHPSVRKAVIEAVQEYGAGAGGTRNISGNSTCHEELEKELASLHQKKAALLFTSCYVANDSTLYTLGKHLPGCHIFSDSGNHASMIQGIRNSNCVKHVFKHNSPYDLEEQLRSVDPRIPKIVAFETVHSMTGKYSKYFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1F0</accession>
    <name>A0AAV4V1F0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013775">
        <property type="protein sequence ID" value="GIY63704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1F0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10421" checksum="DE8015E23E2BEB1D" modified="2024-11-27" version="1">MESSTLSFHRHVQGCNPLNLSTLSQNTPVVQFTYFDKAFPSQSSCIGAQVSQPKAPSGVRAPAKPGSKHKGFVGPLHFHPLHPCAFPLVFTSFLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2Q4</accession>
    <name>A0AAV4V2Q4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gastric triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LIPF</name>
        <name evidence="4" type="ORF">CEXT_321751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013875">
        <property type="protein sequence ID" value="GIY64421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="26"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY64421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="18826" checksum="1846F12863A7B5E2" modified="2024-11-27" version="1">MDFCCQYNGFRLGKMNSVIQKQAKKVVLLQHGLLSASNDWVINFPAQSLGFILADNGYDVWLGNIRGNTYSKKNIYFPSTVHKFWNFSFAEMADYDLPAMIDFILTATGQNQLSYIGHSQGTTSMFALLSENSEYNEKLNLFIALAPVAAVGHIKSAIKLYCSICKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5Y3</accession>
    <name>A0AAV4V5Y3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_166481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014003">
        <property type="protein sequence ID" value="GIY65547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5Y3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8972" checksum="4137041A07D4CA13" modified="2024-11-27" version="1">MSRKGDHIQCFMKRLSTGIIMHPAFLPYLGLWEALITVSSIGHHYCHARRLAAAFSSLHYTSLSVQRTIFKIRGGRTGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6A5</accession>
    <name>A0AAV4V6A5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_807801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014014">
        <property type="protein sequence ID" value="GIY65652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6A5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8994" checksum="2E252BAEAB6FA144" modified="2024-11-27" version="1">MEIFKGRWRVCVKYAERMMMNGFVGLSPLLLARHMGGRRDELFANRTANLCTSAMLCLQNVAVGSILMKHCRTSCRLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7U5</accession>
    <name>A0AAV4V7U5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_745391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014089">
        <property type="protein sequence ID" value="GIY66177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="301" mass="34368" checksum="F7D1549772E187B5" modified="2024-11-27" version="1">MKFSRQGKLIFSTADPVCAAQILNLDKILETPISTAVTFENISERFLVFDIPTNLPLSELAAEIMHKNDMEVVELRRFVKLNSTQEFSPVLITILGTFLPDSIKIWFTNQKIRQFVDRVRQCLHCYDFTHATRVCDRNICPRCGVNHEGLCQGPEKCIHCTGPHSATSKICPRHIHEQKILEFKCRNHLTIGEARRIYAQSSKTNYSDAAKTNTTAPNIEEIVNQRVESIVQNITIKMEQQTTLLIEIFQKTIENLVQYLVSVFHQTDLKKSPNRKRQMINLVPPTNNPMQWDAGGSNASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9A8</accession>
    <name>A0AAV4V9A8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_167229_1</name>
        <name evidence="3" type="ORF">CEXT_101531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014156">
        <property type="protein sequence ID" value="GIY66827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9A8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000017">
        <property type="entry name" value="Raw, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039470">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36300">
        <property type="entry name" value="RAW, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36300:SF1">
        <property type="entry name" value="RAW, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15891">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="248"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY66827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="498" mass="56484" checksum="91F442DD38E3050A" modified="2024-11-27" version="1">MDMFPSSSQVHEMLQCANECSKRPNADYITFGEFCVYASELKSCYDNKIPRPTPLSKPTKETRRLNSRRRSTLTRPSKYQVFLGGSCNPTTWRRDIAIPTFKKLGITYYNPQVAQWGPELIELENQAKQNAEVMFFVIDNQTRSVASMIEAAQIAGTQRKLILVVHEFEKPGSVVMGENITEKEFRDLQQGQRYLQDLVERQGIPVFDNIKHAVQCTATILQKNIKPQDLTIQDAAHPVKMAYLQIGDKLIKLREVFDDLDSDNCSTITLKDIGMAFKILTSTELPVDNLKSIVSQQKDFLGDNLEDGAFDNFRVDFNQFCCIMTELRNQTENGISNLSALRNKASDLLCSVFTPLSKLLDWVRPDSRPTLEEKNNGNDITYATTYRDVYLGGSRRPSLWREEVAIPLLKKKGLLILYLKMVFGAAHYVGLNCQIVLCIQYIEEDTEIDGEKLSSQAVKDYNRGRVYLSDLATRAGVPVFEQVDEAVQCAVNMCLQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9D3</accession>
    <name>A0AAV4V9D3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_447791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014150">
        <property type="protein sequence ID" value="GIY66732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9D3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043641022" description="Secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY66732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19508" checksum="5BD73A09AE0E71D4" modified="2024-11-27" version="1">MYVFAYFVFACAIQTCLVRDIADWGAGVSSTWTSFASSQWQSLEHTSVLSLPIDITLKVCLHWVSKAPLNKEEKKKDPKRGGKQAGKPPPKSKKELFGALIGRCGKGDMFEFESSACGKTVFLPRSQFVSKVPLNYVTKKSCKGLWDTVEEGMKGRVKKYTTSRSRPRLFILFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VC35</accession>
    <name>A0AAV4VC35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_327881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014260">
        <property type="protein sequence ID" value="GIY67613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VC35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8430" checksum="9D8792F43EDB514A" modified="2024-11-27" version="1">MRDHHLQIHSLPKGTLGQATGGINSEPFCTTTGTLYACSLPLYFADIFSFDLKHRKRKALASIHVTIIGKEMTQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLZ9</accession>
    <name>A0AAV4VLZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_14151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014816">
        <property type="protein sequence ID" value="GIY71481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043999965" evidence="1">
        <location>
            <begin position="18"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="16331" checksum="F1399591C6AB68A7" modified="2024-11-27" version="1">MFAKVAFFCAALVAVSAYAPLVNTGVSATSSTQDAYGNYAYRYDIKDAATGSINSKAEIGKVGAVAVAAPAVAYGAYAAPAVAAYAAPAVAAYSAPAVAAYAAPAVAYAAPALAARVAYGGIAAPVLAGRVAYGGYSAPVAYGGVLGHGAALGLGYGAGIYGAGLGKAIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMC5</accession>
    <name>A0AAV4VMC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_10721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014817">
        <property type="protein sequence ID" value="GIY71500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16498" checksum="4A34E34C23D9AD47" modified="2024-11-27" version="1">MGLATTTNDYSHLDCLPDLKTRSVYIATSCQLRNVSMTILSRYSFRRDIFFVRMNLSTMVEDSKVMPQIRLLNNIYYIQLPSLQLPILPAKNPSNILSQGNSGTALIQILHPRFAENFTIVLEALETQQIGSINKSADQQCPFKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTR3</accession>
    <name>A0AAV4VTR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_569801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015122">
        <property type="protein sequence ID" value="GIY73792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10043" checksum="2986AFBF736C5DBD" modified="2024-11-27" version="1">MQRKFSCEHQEVGLPRLDEGRPNDWVNFLQGPQARDEYEAKFRLSRGVIRQLAEQFAPWELFVAPETLSKNGLHACRMVEQRQSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWB7</accession>
    <name>A0AAV4VWB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Myotubularin-related protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SBF2</name>
        <name evidence="2" type="ORF">CEXT_353221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015232">
        <property type="protein sequence ID" value="GIY74577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005112">
        <property type="entry name" value="dDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022096">
        <property type="entry name" value="SBF1/SBF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF16">
        <property type="entry name" value="C-MYC PROMOTER-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12335">
        <property type="entry name" value="SBF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00801">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="1">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="468" mass="52347" checksum="2FF3B2E9409D0235" modified="2024-11-27" version="1">MCSSTPPGEYFCECGPQVRFSIGAGDRQALQPPLSATLLVTGTTVYQLFEELGIHNVVTLFCAAMTEHKILFHSSSYSRLTDACHAVTALMYPFKYSHVYIPLLPSALIEVLSTPTPFIMGLDVIVVDLDGGSLLVPECINVSRLPEPLHSVLYSHMCKVLRPELKSADDAFPPGQIKPSPPHMLLLQGYRSCLTIIRIHPRPFITFHKAAFLGQQTYSDCDFIIKVLDCMFFNTFVSERGPPYRVCDIFDEIYASMQDTLKAESKDMTTVLQHIQELAQQLYLNENPNPQPYVQKIPKPTEGAFTRIHQPTFPIICVKTVQDIIDEGMSKQSLRAKLSAIKPQQPRIVPMGTQASSWLDSRNLVTNSARRLEVLRSCVNCIFENKISDARKTFPAVLRALKNKTARLALTQELALHVTGNKAMLEHQQFDLVVRLMNCALQDDSSMDEYGVAAAILPLAMAFAEYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2B0</accession>
    <name>A0AAV4W2B0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_708941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015437">
        <property type="protein sequence ID" value="GIY76111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2B0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043551331" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10467" checksum="719201B10B84CDE2" modified="2024-11-27" version="1">MRMVLKITFAMRMVLKITFAMRMVFENNLCNAYGFENNLYNTYGFENNLYNAYGFENNLYNAYGFENNFCNAYGFENDLYNAYIVLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDF7</accession>
    <name>A0AAV4WDF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_385731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015952">
        <property type="protein sequence ID" value="GIY79996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11979" checksum="B23C72941D77185E" modified="2024-11-27" version="1">MSVDIPLLFLKSSTQQQFVSFDVSAPNSGNLERTPRVINVSSRYHLPPKQPNMQKKKKKKVGKKNQEAKKRQKKKLHSELAAEVSAVKRCTNKKGAHRFPNQLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIF3</accession>
    <name>A0AAV4WIF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_34471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016265">
        <property type="protein sequence ID" value="GIY82626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19013" checksum="05B49DA82EBE79AB" modified="2024-11-27" version="1">MRFVPGQPGDERSGLSNQRTKPSTQMPAQKQATDSTAAVKLEKQLAVSCQSQSVCRSAIASDLSPLGNIRPKRPAAATAVHEVRRSFQRVKCHCTTGTPGHWVTKTLLLMPGCCHFSTAAWNLQQQSGVSIHNECSMVEKGKSLMWRPHRLCQLSDVEHSKKPHEGTDGLNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WKV4</accession>
    <name>A0AAV4WKV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_177601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016386">
        <property type="protein sequence ID" value="GIY83437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WKV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY83437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="31012" checksum="B2C7D8D3DD2FEF69" modified="2024-11-27" version="1">MALFRERWCPRPTPTLIAQHREKTARQWNSNKKRDQSNNGLGNKRFQWGIGGRDGKKLQALHSGQLQSSMSHLFHHTPPPFFFRVLYYPDPKWNFPTVRKTVNIPDFHPTLEQIRGLCKCGNATYGKNAFKVFQGLKNDSSRIRKYSFPPKRKKSTAKLQSNFIAVLFKENKLIPSLLCLPLHVPNLKEVEERERIMKRRTKNIMVGTCAFPQKLICLTSLLKVLQYPIHFPRAKTAKCLLEKGDHLEGANAFIWNLNNRRSNGEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4T5</accession>
    <name>A0AAV4X4T5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium-dependent serotonin transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SerT</name>
        <name evidence="10" type="ORF">CEXT_244251</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017176">
        <property type="protein sequence ID" value="GIY89180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4T5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051378">
        <property type="term" value="F:serotonin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005335">
        <property type="term" value="F:serotonin:sodium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF279">
        <property type="entry name" value="SODIUM-DEPENDENT SEROTONIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY89180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="250" mass="28314" checksum="77F86B3DBAFD4F01" modified="2024-11-27" version="1">MAHMLKKDISNVATDGQGLVFVVYPEAVATMSGSVFWSILFFLMLITLGLDSTFGGLEAMITGLCDQFPIHLRRNREIFVGFVVVFIYLCALPTCTFGGYYIVHLLDSYGTAMSVLFIVFVEAAAVCWIYGAERFSDQVKEMLGHRPGIFWRVCWKYISPIFILCIFIFAMVQYKDLTLQDYNYPRWAIGVGWLLTASSLSCIPGYIIYYLITTPGTCIERIERGLNPETQTQQKQERIPINTRLIIGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEA3</accession>
    <name>A0AAV4XEA3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prolactin receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_358541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017501">
        <property type="protein sequence ID" value="GIY92119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17925" checksum="A1F1CC84FD5136DB" modified="2024-11-27" version="1">MAKVMWGSRDHVTVPSPWQPPLENSLLTRSAEGRQCEGEASSYLKDPNIALFKPSPNILTSERPEIQAEGEKLLQSTDGPMEIPNRAHPEAFKYLKDPNIALFKPSPSILPSQRPERQAGGGLLQSTNGTMEIPNRAHPFNDDGREQRSLRFRTKHSFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEZ9</accession>
    <name>A0AAV4XEZ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transposase IS30-like HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_148040_1</name>
        <name evidence="3" type="ORF">CEXT_627421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000129">
        <property type="protein sequence ID" value="GIY92358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase IS30-like HTH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY92358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="18312" checksum="62AA7D7B6A21DB86" modified="2024-11-27" version="1">MDLKGKEITPKERKIIIKLRNEGKNSFREIGKIVGRTHSSIQRVINNYTSSKSIISKPRSGRPSKLTAREKRYAFKSRVIITEWNNISSEETSKLVHSMPKRLTEVLRRRRLIECISSQQAFNSLKLQNKSNFSGQQLKIINIQIKQDCAELKRRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF36</accession>
    <name>A0AAV4XF36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_194661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000174">
        <property type="protein sequence ID" value="GIY92639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13016" checksum="C48E23553006B3A5" modified="2024-11-27" version="1">MELPTRSSGDPFSNSLSPLNVRRFSHPLPQSKVTEKKNIPNIPSLTLSQFASVPLVTTAATHKKKEYLVLSILFAAPSSSDFRLISQNNDSADFVRAQTREDVPRHLLITLLIIENC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGB9</accession>
    <name>A0AAV4XGB9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_581242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000292">
        <property type="protein sequence ID" value="GIY93677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGB9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10169">
        <property type="entry name" value="ASKHA_NBD_actin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="81473" checksum="BBC9A06B069E445B" modified="2024-11-27" version="1">MSISECINTLATFAETVEVIECLGNYFYKTYSSQYLDNNHKDRPSDAWTANSSQIYINTKNDLQTRGSTSSLSSTSIDTNILDCQTPDILDSSPRNEEVPLAENDRLVYSDEDSYHSCSLLDSSNTKSSNIIATNKSVLHEPLNDTSNEIHKLKDNSFIKTTNFINSDTAVEKENGFQVDEFLEYNKNIPERDKNKKEIYGIKKLTTSSWDLEAIIEYLYSLPEPKISKVVPEVNGSTKDILVKSQGAFCKYPEGNYTLELQKQLVVVKQETNILVKMLLNYAEISTNGNILQLDNKVGRCLYLKCASKEELLELKQELEAHCFKCWSSEQINLVHYPLKYHQNVVIIDLGSCSTRAGILMDQATLPFIFFPSVCAINKVTGNHIYGKEALQNDVRQNSNLSFPIRPSVKIIKHSIDIGLVEGLFKKIFQDLKVDPSQYTIQVCLPRNLSIHDQNSLVKLLLEDLKVKAVSLTHQALLTLYAHNVSTGIVVDIGDRMDILPVVDGFIVENGVTRLPHGGQRLIHHMKHALAEKHISLSNDIDSFVVQFISENLSYIAEDYESEIQIAKQNPDIVKKSVALNSFTKDVDCIQEAVLDDARFKIPEGLFKPTLWGLDNPGLHKLTQKAIQATGVDVRKKIAENVYVSGGITMIPGFVERLLKELSNLNKPRITPKIIASRYRYHCTYIGACEFARMEVFPRVCVNAEEYSKEQLASLKRFVLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIH1</accession>
    <name>A0AAV4XIH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleolar protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NOP9</name>
        <name evidence="1" type="ORF">CEXT_338721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000281">
        <property type="protein sequence ID" value="GIY93574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9840" checksum="47EBC01D6C65A68F" modified="2024-11-27" version="1">MFEGILSSRFYGIFLSIADTCNRLKIQQAQFTKNIMLCLQCLEPEEKQIQLVPRALGFLVNDQPKLSICLQGSLLVQALLKFQKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJC1</accession>
    <name>A0AAV4XJC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_560811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017819">
        <property type="protein sequence ID" value="GIY94749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11245" checksum="60CF2AAC1BCA15C6" modified="2024-11-27" version="1">MQWRPPSFIAVVEIMEQHIDEVADAVCIPKAKKTEESTDFVGLSSVTSERIWSDRLERLVQLIWFMEGLGRSGVYSFCPTRCLSGCINPPAPGARLDLSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMD6</accession>
    <name>A0AAV4XMD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_789421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000585">
        <property type="protein sequence ID" value="GIY95844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14616" checksum="5E1F3D498F412DC3" modified="2024-11-27" version="1">MVLPKQRRPGSFAYATSMAAFLCQDWAWKKNRPITLKLPGILAPEMTRIFGIGSSFRRSSEQFRVMPLLTELLLIESKFLFPDIWAMGNNFTLDYALYLKVCYIDINLKLLDDKSYLLEVLLITIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPB4</accession>
    <name>A0AAV4XPB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_763981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018107">
        <property type="protein sequence ID" value="GIY96957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF5">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15661" checksum="8289EAACF091E2D6" modified="2024-11-27" version="1">METIRPSVYPSVRPSIHPSVRPSIRPTIHPSVRPFVPPAIRQSFQPFIHPSVRLSIYPSIHPSVQPSIHPSISPPIYPSVHSSIHLTVHPTINPFVRSSLHPFIRPSIYPSVHSSIHHPSVHPAIHPSSHPSARPSPVIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPT1</accession>
    <name>A0AAV4XPT1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_339661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000614">
        <property type="protein sequence ID" value="GIY96074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12223" checksum="030D0936ECEB5B63" modified="2024-11-27" version="1">MYSSLPSGHRVTGIFPPPLCDRLSESDISASGVEQVFRCEKKIALSTCHCNIPQFYARFCYNPVRINVAFTTLCFTATATVSEMLFYGEKSTELAIFDAVCKPGRLLITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQM6</accession>
    <name>A0AAV4XQM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_305711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000773">
        <property type="protein sequence ID" value="GIY97361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11866" checksum="C38DB97928DFDAE9" modified="2024-11-27" version="1">MRLAISKRKCAMARSSFTRTANVLKEEPHKVEPDKSVLEDKFIKLQTVNTELKNYDSVILDLMMAAEVSDDDLNNEVISCEEYLDEFISLSRRIKEKRIIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTG4</accession>
    <name>A0AAV4XTG4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="1">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ubr3</name>
        <name evidence="2" type="ORF">CEXT_325371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01000730">
        <property type="protein sequence ID" value="GIY97038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF39">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="640" mass="72973" checksum="FE0BB216B8690E7D" modified="2024-11-27" version="1">MAKEAAEVLIKKGKRATAAYIQGVCSSQSNTDVTNEVFDSILNPLAPINSWNGIDWCRWLLAGGKAPEDYTQTVRRYDNATTCGLVWTANFVAYRCRTCGISPCMSLCSECFQKVITKAMILTCFAVRLVEPVIVETKVFSDSHDTAMHFADNFLSLLQSHSEMGAAMRSVMTQALTNPQIYYMLAADCESGNNLQYRRENLNQYLDARNSLGPTEEDEDISSDEERTWFAADQLKDSTFLEELVFWTIKFEFPQKLVCLLLSMMPDLTYKEAFTKIFVKHYGLISPEKNEHLVVDCGHHIMKEHCYWPLVSDLNNVLTHHAVAHEFLNDNNLLDQWFKFLSLFQGMNVNQRELKAHVEFESNTYYAAFSAELEASATPMWALISHLKAADTLDKTKSVLNAAIQALQTWFILIGFSVGDEINPYQVSFHIPLHRCFASFLGQAVRQQGAKLDSLLPSEDTLKLLMMHPLQAQVAFHEILCNMWVRSGLQIKGQAMTYIQCHFCNSIVDADLFLLQLCAMKLDPDWFLTTVLQKGNLIRFHVWEWFTFHPNRNNTFLDTDKVMPMLEGALSFLTMLLSTHTNTGLTEEEVIRQEMVSRFLCMNDRTHSQLMDLIPDKCGETAQNKNFETILNQVNNVTLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTI9</accession>
    <name>A0AAV4XTI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_576841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018125">
        <property type="protein sequence ID" value="GIY97174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17302" checksum="D424603CA3969A25" modified="2024-11-27" version="1">MEGGLKTTEYRPVWDSFKPFGFNYNILKKDGQTRNSRSESADGSGRVQGSYFLNNDEGHFREVLYQADKDGYKSIIRTNEPGTRSSNPASVFIEYTTEIGRKFKNMAKESIAPLFNSVFGSSSDSGSAPRKRSPPVEEARINGKGALFTPKKKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ19</accession>
    <name>A0AAV4XZ19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_470371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018395">
        <property type="protein sequence ID" value="GIY99196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14713" checksum="E27904E06EC909DF" modified="2024-11-27" version="1">MTLRVPPWITKSTPLLGVPIDQPSASNVIDSADMEYNTAPQPITQTDDLVDISISTVRQLVYLREHYTIFRNDTADMKRTSSSADSIHNSDCKILEFYSRNNDQVQHRISQTILNLQFCIYLLYSSVASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3C2</accession>
    <name>A0AAV4Y3C2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_538691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018730">
        <property type="protein sequence ID" value="GIZ01843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3C2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11141" checksum="8EEBD9BB98A5DD58" modified="2024-11-27" version="1">MRPSFADKADFLGCQIAGSDNDAKHDVIHFERFLNNIVLLSSLSYLRLSTENLRTILVNNEISLKGPDSRETSDMAFSTTGLGLESGRAMNVCNGSESTQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4G6</accession>
    <name>A0AAV4Y4G6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_738631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001251">
        <property type="protein sequence ID" value="GIZ01090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4G6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10020" checksum="B97BC394B2D8357F" modified="2024-11-27" version="1">MKIKSLRKRPMSSIANICNICNAILTAKFLDFSLVKELSISQRKELFIVRTLNESCEHRAESQLGRLSTLLMKKPRSQNRLVSNNGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8F1</accession>
    <name>A0AAV4Y8F1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor SUM-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SUM-1</name>
        <name evidence="2" type="ORF">CEXT_408671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001585">
        <property type="protein sequence ID" value="GIZ03300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8F1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13251" checksum="3111B501F7561B26" modified="2024-11-27" version="1">MVPEMRSCRYQKTPPPTTTPPYVTSTTHRRHYDSSYGNQEYSEAGTDFQCQYNSGRYYACGEERTYQQQRAMDGLYVMNPAIRADNINNNYGYERGVDGLRCQSSEVSTSSEDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFB8</accession>
    <name>A0AAV4YFB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_550671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019159">
        <property type="protein sequence ID" value="GIZ04867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12491" checksum="D9A9C1AB4308ECBE" modified="2024-11-27" version="1">MDNEEAEEKTIAKYLSQQKSNSSPSTFQNQQFRFGKNYRRQCRKTQEESDYPSLTSGYTNTLPPSRKQWQQQKMVICRCNNLHGMGFSEKENDFSRPFLLFDVGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3P8</accession>
    <name>A0AAV4M3P8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_533511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001814">
        <property type="protein sequence ID" value="GIX66696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3P8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14318" checksum="0D9CF94B82352CF1" modified="2024-11-27" version="1">MLDDIISEKTFESAFSNRHRLMTSSISLVNFEGEEENGPFPVQPELLPILKFRASRGLKKTLLWTDSTYEGKSRNLPSNKAKLNNKFETLEQCRYLHGENVDSIVTMFKKSLDYEFGSMENLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7B0</accession>
    <name>A0AAV4M7B0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_308451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001945">
        <property type="protein sequence ID" value="GIX68278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7B0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="9797" checksum="8853919E0A76322B" modified="2024-11-27" version="1">MLSIVLISRNCGLIKVLNLESSRISTEMVLLFEAGQTMGDAPIIFVGRLLRTSGATFPSESSPPLSGGPPRYCPAISANRNCQNGSICAHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAD7</accession>
    <name>A0AAV4MAD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_162511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001960">
        <property type="protein sequence ID" value="GIX68381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8965" checksum="20112BCB45135449" modified="2024-11-27" version="1">MKILMKGVVLPQFRLRELSSLLYKHHITDSDSDFMDLESDNSDDDDDGHRLHLMTESSCHIKTHMLRMRFMMWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLP2</accession>
    <name>A0AAV4MLP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_484891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019876">
        <property type="protein sequence ID" value="GIX72783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="28478" checksum="E5CFD12ADAD4590B" modified="2024-11-27" version="1" fragment="single">SLEECLQEPNSNNSPNSSFVGIKEFQDPQIHQFTGEEVEYELKAIEQSSYKPHGQRSYNTNYDKENTVSSHFDSDQALTSSNDGWNSFSVANSVSQECDSFESLSIKTPEFISISQEIENIIDILNENKKNWKSIMKKERNFGKYSTYILHHPNTPHTSSTTPNTPHKSSTTPNTPHCYSSSSVPMQLSISNYDILPLENDLRCLSTKKADKSRSPKSNYPKIYTKWDSEARIALLTSTSFFAENSYSRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRF3</accession>
    <name>A0AAV4MRF3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">RPA1</name>
        <name evidence="16" type="ORF">CEXT_772051</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9 11">As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002546">
        <property type="protein sequence ID" value="GIX74979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000090">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000117">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11 16" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="12">
        <location>
            <begin position="174"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="15">
        <location>
            <begin position="283"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="14">
        <location>
            <begin position="437"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00058595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00062035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIX74979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="593" mass="65628" checksum="A5EE215D32EE0329" modified="2024-11-27" version="1">MVPQLSTGAINRILNGEDVASAVLQILGCKKIPGAGNDRYRLLISDGVTGCPFAMLGTQLNHMVTNKELEKFTIVRVDKCVCNQVQADRKVIILLSLTVLAPGNEVNEKLGNPVNSSAGGAPAGTTATSVVSAAPKTSYSSLSSGMASRESSMLNGSAPSVHPINTLTPYQNKWTIKARVTNKTPVRVYSNSRGEGKVFSVNLLDESGEIKATGFNDAAEKYYDMLEVNKVYYVSKANLKTANQRFSTVKNDYEITFNNDTIIMPCEESASSIPMLQYDFIPIAQIEQVEKDSNIDVIGVCKSCSDLQTFVARTSNKELTKRDVKLVDRSNKEVSITLWGKEAESFDGSLNPVVAVKGARVSDFNGKSLSVTMSSFMLINPDIKEAHVLKGWFEREGCNLDAQSISGKGASSNMGGQWKTFAQCASEQLGMGDKPDYFVNKGTIVMLRKENCMYMACPGEECNKKVIDMNNGIYRCEKCNREYSEFKWRLLLSISIADFTENQWVTCFQEAAETILGVSAQELGSCKENDEERYNEILTEANFKSYIFKFRTKMETYNEESRLKTTVVTVTPLDPVTYTRKILSDIKQMEQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZ34</accession>
    <name>A0AAV4MZ34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_383201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020304">
        <property type="protein sequence ID" value="GIX77179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZ34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039524">
        <property type="entry name" value="PIGO/GPI13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071:SF1">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043763989" evidence="2">
        <location>
            <begin position="24"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX77179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17513" checksum="1B240618F5F93D25" modified="2024-11-27" version="1">MLMSFSTVLFSILIQLSFDGSESYIWTDTIILNLLSRHWFYATAHQPTFTSIQWDAAFLLSHKEIHSYILSGALVIINTFSSFIFHGLALPVILIMRDSFFITTHSILRLHMKYLFCFGVKLLGTIITSFILRRHLMVWKIFHQSYSMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0C6</accession>
    <name>A0AAV4N0C6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_563501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002757">
        <property type="protein sequence ID" value="GIX77463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0C6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16679" checksum="F53A1B217382D8A9" modified="2024-11-27" version="1">MGNDAKRPYFFHNISQAAFQSDTHQKLCIPTPQCNNSEPKIGARLHVCFVKSALCSRFPWLPCDYHKKSLQNRLIRAHPFHSIISVVCSTGQTYWSVRILNAAGLQEDGYLETGAVGHLRRKRTTKGDLSRACDEGFAIVGLILFQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N194</accession>
    <name>A0AAV4N194_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein ST7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ST7</name>
        <name evidence="9" type="ORF">CEXT_452121</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ST7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020410">
        <property type="protein sequence ID" value="GIX78448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N194"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd11557">
        <property type="entry name" value="ST7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007311">
        <property type="entry name" value="ST7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12745:SF6">
        <property type="entry name" value="PROTEIN ST7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12745">
        <property type="entry name" value="SUPPRESSION OF TUMORIGENICITY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04184">
        <property type="entry name" value="ST7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX78448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="520" mass="58804" checksum="06899CF5CAD7143A" modified="2024-11-27" version="1">MASLFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSLNHISPWLGGGDGNGDTASNGSSSEGGGGDSGGGGGSGNGNSTNNNNQQAAFECKVWRNPLSLFRGSEYNRFLWTTNKEPLTYYDMNLSAQDHQTFFTCEADGNKPEYEIMQTAWRERDPEARVKAAHQALEKNPECAPAYILLAEEESSSILESEKLFRQALKVAEVNYRRSQQLQHQGPTQETMHRRDTNVLVYTRRRLAMCARKLGKLRESVKIMRDLIKEFPMMNVFNIHENLIEALLEMQAYADVQAVLAKYDDINLPKSATICYTAALLKARGVFPDIASKRGLSTAEMNAVEAIHRAVEFNPHVPNYLLEMRSLILPPEHILKRGDSEAIAYSFFHLPHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPTCTETTDRELLPIFHEVSVYPKKELPFFILFTAGLCSFTALLALFTHLYPEPMGTFAKNAVGWLSLPLGYMLEKVEAMLPSSLLHQLSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N797</accession>
    <name>A0AAV4N797_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_751451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020581">
        <property type="protein sequence ID" value="GIX80288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N797"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1520.10">
        <property type="entry name" value="ADP-ribosylation factor-like 2-binding protein, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042541">
        <property type="entry name" value="BART_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8274" checksum="3E700F4D54E85326" modified="2024-11-27" version="1">MGTRHSLLTSGQCGPHRTPDDSEMADEENFSWVFESLVGFLKGPVWEAAVLTFIERKSCSIQWTAMRKNTKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCA9</accession>
    <name>A0AAV4NCA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_608081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020765">
        <property type="protein sequence ID" value="GIX82288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13007" checksum="00ADE6B97B67FD12" modified="2024-11-27" version="1">MAQSRSGNSTPTPYSHPRFSQLKRESLLPQTRRLRLSSIRSRDLKKGSSSGKTLSFLVNRRIPRDLLQFLILAKSVLHHPGSTFTSSRAFSLHKNRVSMQCHAFFFYHMIEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLP1</accession>
    <name>A0AAV4NLP1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">CEXT_105391</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01003539">
        <property type="protein sequence ID" value="GIX85712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070611">
        <property type="term" value="F:histone H3R2 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000031">
        <property type="entry name" value="Putative Histone-arginine methyltransferase CARM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF10">
        <property type="entry name" value="HISTONE-ARGININE METHYLTRANSFERASE CARMER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06325">
        <property type="entry name" value="PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="14">
        <location>
            <begin position="258"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX85712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="595" mass="66338" checksum="E3EE676E64B7A6C1" modified="2024-11-27" version="1">MAATFEDVLVSSLSEDMKKTEKIPFPVTLFVADEFENLSLVFKPSGTNGPDSLLELQFDKDTDGAKLGSHSYVITKEMNSLHLQFRNANDLSRFRSLIDGFKNGKNSMFSIRTDESSATQYFQFYGYLSQQQNMMQDYIRTSTYQRAILANLDDFKDKVVLDVGAGSGILSFFAAQAGARKVYAVEASSMAKHAETLVYHNKLSGQVVVVPGKIEEINLPEMVDVIISEPMGYMLFNERMLETYLHAKKWLVKMFPSRGDLHIAPFSDAALYMEQLNKANFWYQQSFHGVDLASLRDAAVKEYFRQPIVDTFDINICMAKSLRHTVDFQTAQETDLHKIEIPLSFTLNQTGEIHGLAFWFDVAFFGSTQTVWLSTAPTQPLTHWYQVRCLLETPLFAQRGHIISGKVILNSNKDIEVGIEGSNMRGYNTLDLKNPFFRYTGQPAQPPPGCNETSPSEGYWQTLDVQTANNANLVMNGITLMNGDTVMDAHPVQHHLSHNPITSHQTNTVLPLGNIQNSGNNPISRTTSRIQASVPTSSIGGGISPSLFTQQQQHVVLGNTTHFPVSNSLMIGDYATPGNIVMPGQIDLVNAFKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNF9</accession>
    <name>A0AAV4NNF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_75751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003514">
        <property type="protein sequence ID" value="GIX85461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14467" checksum="E398F600727272F2" modified="2024-11-27" version="1">MSFQKSKTAAGTQYNSFRTPDLTLLPGRKIIFQPFRQWRRQTITLSDMKALPIPSSIAMTTGNYNVFSTLFSLRTVRDTNCYISKLQIECFRSNQFLAARKVIHFPFNSIYTSFPGYMHSLPYCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPG3</accession>
    <name>A0AAV4NPG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021092">
        <property type="protein sequence ID" value="GIX85791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16753" checksum="16E7ECC82B80C96F" modified="2024-11-27" version="1">MMDNELDLRNKGRPVLNQINEAEPFRIFILINLEPLPISHNSSKSLYPKLTLISFPDFKQIHGIHFMENWLKASRRAENISKGCSSPSTSKIPLILVQWRWDLDYQGPNDCSKADKHNIGDIKSGRPKYWVGGPKIKGALKRNPGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRL4</accession>
    <name>A0AAV4NRL4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_556981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021130">
        <property type="protein sequence ID" value="GIX86321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15624" checksum="4476610EA7B36F02" modified="2024-11-27" version="1">MPTEVGVDEEKSGLLSIVRSEIIAWILDSTLFFLPLVRLPSGSYLTVEALFNNFEDDTKTNKERTLMAHCHYNVAGKSKHVLANRLLVTSDLCVSPTVTRSTQFTPNAIMARLLSIVFLIVCGSPNTTFYFAVASFGLYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0C2</accession>
    <name>A0AAV4P0C2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_49021_1</name>
        <name evidence="6" type="ORF">CEXT_586831</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003961">
        <property type="protein sequence ID" value="GIX90667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0C2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043236">
        <property type="term" value="F:laminin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043113">
        <property type="term" value="P:receptor clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.30:FF:000024">
        <property type="entry name" value="Transmembrane agrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004850">
        <property type="entry name" value="NtA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008993">
        <property type="entry name" value="TIMP-like_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03146">
        <property type="entry name" value="NtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50242">
        <property type="entry name" value="TIMP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349209" description="Kazal-like domain-containing protein" evidence="4">
        <location>
            <begin position="24"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="125"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX90667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="21191" checksum="540DB07762F05321" modified="2024-11-27" version="1">MYLSKSYLLLLGLVIFQFDSSAARRRRLFRECPEERLKVRESTADVVLTGTVKRLYSGQDNLYSGEVLVKRVIKGDHLSPGESLLVEGFGNSDICTSIPYRRRPPITDEPCEKKHCKFNGDCFEENRRPNCRCPTNCKEHYNPMCGSDSFTYNTECQLRVDSCRKKKNIYVRHEGLCSRTEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0V1</accession>
    <name>A0AAV4P0V1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_547941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003873">
        <property type="protein sequence ID" value="GIX89534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0V1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11664" checksum="2041EB70FA13F5F1" modified="2024-11-27" version="1">MCHTYSPMTEYHPSASLLGFHREKRERGLLTRMWEKPYCLQSPAEPPRTKLFPSSLARFSLTTKQVVSWWVTVSTFCSQCFDLRSSLSMWKRMDLRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5F6</accession>
    <name>A0AAV4P5F6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_77231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004006">
        <property type="protein sequence ID" value="GIX91263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5F6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9492" checksum="D10F384B7BEADC59" modified="2024-11-27" version="1">MPRSIASVLFTDGGSFINVKLFEERIVYRIVRLLLLKPPHIPPLECVEFLNDSNRTLSSCTKTSSAEERQDQRRLFLIETVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6W3</accession>
    <name>A0AAV4P6W3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_462101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021718">
        <property type="protein sequence ID" value="GIX92784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6W3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12282" checksum="634CCF41A3C3BD10" modified="2024-11-27" version="1">MGTIHVVDTRHANSTTHRAPNDSDNRPLVDDNDNLFDIIIYNGRWPYWTIVDRSVVFHFYRPPPLCHPLPASSLFCAVVVHSSFCPKKPSPCPIEKEENRKVRLLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBW6</accession>
    <name>A0AAV4PBW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_90721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004143">
        <property type="protein sequence ID" value="GIX92637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11768" checksum="31430DDD0F21EAA9" modified="2024-11-27" version="1">MRYTLEIERLFALAIDSDPVYKIIFPKHFLVKYKLLPFPIMGSKKEPFLRPRSRKSALLSQNCSPRRGATPSIFPTPSFSAIIFVYFFLFSQETAAVFDAVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGP7</accession>
    <name>A0AAV4PGP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004662">
        <property type="protein sequence ID" value="GIX96557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="13911" checksum="347241C72E53D094" modified="2024-11-27" version="1">MEIKSVVLRRKSVLQKLATSGNQRACLLGVISCFYRPDVLLLGDLSLSCSPVISSLAHQKQSTAQSFHNCSFHKRLNGRPLSALETLEQTGGLSSPCITSSLDFSNQVLLPSFLGCGKLFVIYFINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHB7</accession>
    <name>A0AAV4PHB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_665331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004653">
        <property type="protein sequence ID" value="GIX96474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15217" checksum="373E98C6124D97A8" modified="2024-11-27" version="1">MGLAGIRNSIPHVMLMVGIRNGIPYAILMFDIGNGIPHVILMFGTRNGISHVILMSVIRNGIPYAILMFDIGNGIPHVILMFGTRNGISHVILMFVTRNGIPHIILMFDIGNGIPHVILMFGIRNGLPRVWQQKRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJC1</accession>
    <name>A0AAV4PJC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_446201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004689">
        <property type="protein sequence ID" value="GIX96754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9518" checksum="C8E52F56BF0DA5F7" modified="2024-11-27" version="1">MDGNAVESLQKAMKALEGHKDLKGGSGAPSARLLQRPSLWRRDLPRKDAEGHPKIPRRRGNAGTTPVCRAEAPTQVEQQIPQSQPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PL41</accession>
    <name>A0AAV4PL41_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_284041</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004768">
        <property type="protein sequence ID" value="GIX97354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PL41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000054">
        <property type="entry name" value="Complement C1r subcomponent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX97354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7584" checksum="F4DB05E133E664B0" modified="2024-11-27" version="1" fragment="single">VNDTCQGDSGGPLMQSQLNDDGYIYWTQVGIVSWGIGCGLPNTYGYYTHVQRLVEWITNTIDSVKIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPA9</accession>
    <name>A0AAV4PPA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_533031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004813">
        <property type="protein sequence ID" value="GIX97730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11090" checksum="13F15895A2D32209" modified="2024-11-27" version="1">MRDKGWQMACAREALIEQVASECENRGAPTIRTGFAVAGMDFEQRMHDFSLLKIRQRVEGKNGYLAFFLFLLDVCLSWDAQRCVFSLNSCHQLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8N9</accession>
    <name>A0AAV4Q8N9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_350901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005728">
        <property type="protein sequence ID" value="GIY04577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8N9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8507" checksum="BA2770817FE9851A" modified="2024-11-27" version="1">MSASVALTPEMSFLESSTHPRPTPMTLFDPLAVIRSPEETEQKPIPQNLRTIRWFPQTSLCQNTFEIISKKYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA95</accession>
    <name>A0AAV4QA95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UNC93-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CG4928_3</name>
        <name evidence="8" type="ORF">CEXT_593851</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-93 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005819">
        <property type="protein sequence ID" value="GIY05247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055120">
        <property type="term" value="C:striated muscle dense body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015459">
        <property type="term" value="F:potassium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006937">
        <property type="term" value="P:regulation of muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043266">
        <property type="term" value="P:regulation of potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051951">
        <property type="entry name" value="UNC-93_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444">
        <property type="entry name" value="UNC-93 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19444:SF11">
        <property type="entry name" value="UNC93-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY05247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="495" mass="55369" checksum="08780D0B7D971D4E" modified="2024-11-27" version="1">MSDRRMPNVVASGREYSPSETTPCLLDPTLQRNSSNMTLNFTSRSRILKNLFVVSLGYCLFYSGFWALTNLQSTMNAVAGMGPDSQAVIYGFSMVSSLFLPELTIDRFGCKTVLIGTSFLCLPYIAANIYLRWDSLMVSSALYGLASGPFSAALTVYIDEIALRFERTVDENVECVMSTFFGAFAFSMENTQVWGNALSYFILKPESHIPSNLNVSLPEDCGIHFDPNANATNTNLTPPTAEERYLLVGIFVGMGLLALLLFGLFLDPLRNDIKREGCDAIAGRFVSSLRHYRTLHQILLIPLTVLIGIESALYSNEFTQAYIACSWGVHHVGFVTVCFRGVRGHHVPVGGPAGQVHLPDGGADARRRRQRRHLHRPLPVAAHARVQDYVLRHSRRLGNGRRHMVVAGHSSLWFDVPKRQRSCLFQPVLLEFPGVLPQLLVCQLLHCGRQNKHSALLPAHGHAGIHDRPTEDQVHCQERIRCHSRQRTKFLKTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDD8</accession>
    <name>A0AAV4QDD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_399821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005921">
        <property type="protein sequence ID" value="GIY06050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11328" checksum="9A997B89B8F3FF11" modified="2024-11-27" version="1">MKQCNILILIEKCLVNHYVENQRGVFISFVKNLDFAINSQVFSEKISFVVSELFCYSDFHAALKQKISPFTCRDKEKTVSPLTLLKATAKRHEIRVCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QE89</accession>
    <name>A0AAV4QE89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_173881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006191">
        <property type="protein sequence ID" value="GIY08038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QE89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11642" checksum="7079DB4349D73922" modified="2024-11-27" version="1">MRMFLCGCLSEARVLRWFGKRGRQGRDTDGRSRADRSDAVIRRSLFCAVGKNAGAHVMDVAKEENFTPANPINFAKQFSFPSSNENCSFSFDTFFLHDTLLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QG40</accession>
    <name>A0AAV4QG40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ecotropic viral integration site 5 protein homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EVI5</name>
        <name evidence="3" type="ORF">CEXT_375621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006088">
        <property type="protein sequence ID" value="GIY07326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QG40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000002">
        <property type="entry name" value="Ecotropic viral integration site 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF22">
        <property type="entry name" value="RAB-GAP TBC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY07326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="18009" checksum="50A147F2931E4D3B" modified="2024-11-27" version="1">MPEEDAFSVMVRLMEDYRLREMYKPSMAELGLCMYQLECIVQEQIPELHMHFQTQSFHTSMYASSWFLTLFTSSLSLHLACRVMDLFLSEGMEMIFRIGMAILQFCKEDLLQQDMEGMLRYFQKEMPAKCEADPDYLIGVAMQVKYSSKKMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJW4</accession>
    <name>A0AAV4QJW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_738791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006404">
        <property type="protein sequence ID" value="GIY09589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7980" checksum="7EDE099B3B35DEAC" modified="2024-11-27" version="1">MFEVLTTPAHEFRVEPKKQSHTKMITCWHKKFPREAEKALHHLKSFTHVEAAWPDGDRFEHWLVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRX3</accession>
    <name>A0AAV4QRX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_386181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006593">
        <property type="protein sequence ID" value="GIY11019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12076" checksum="7E792BB623D31735" modified="2024-11-27" version="1">MKECVPFWHVIFGVYLAALLILKLFMLAIIGSEIRDGFYEIKTIILNAPTFEEKSFNDTLCLTKHVALSQIVESMSENTYMTAMGIVKIEKVSSSPFYVLALVTVFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWB1</accession>
    <name>A0AAV4QWB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_251701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006956">
        <property type="protein sequence ID" value="GIY13540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8953" checksum="28E8D08E572BC954" modified="2024-11-27" version="1">MLRDDSQASITQRCMTACLSDWFKFMIRMLRHDSRGACHNERPLPKDAWRDRERQGCLREMYFTGGLHLHPEMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0L7</accession>
    <name>A0AAV4R0L7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007112">
        <property type="protein sequence ID" value="GIY14594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15711" checksum="A606C18CB85F30C2" modified="2024-11-27" version="1">MGRSRGNDEAFGYGRYEATSTINDWPATPSRLSTDFVRTWQVIRQVDCRTPVDRKGPSAIRPQSHFHVIQDIGTGREPQRFPERMNGRKQKISLCHIARSFTKTHTYIHSPRAVPKLVGQIARSVSGTVRLPASRGPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R202</accession>
    <name>A0AAV4R202_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_70521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007249">
        <property type="protein sequence ID" value="GIY15574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R202"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23818" checksum="E580E4CF76BCA7F1" modified="2024-11-27" version="1">MTTITWSSLNIDSFLEKYSECVAHIESLFDRLCKILNHRVDETLSQVAEVELCPVAPENPVTIQAFSTILSASAAEGADFLEKRSLAVEDAVQEVIQVFVKESSFNEEEEKKISFEENSMKNPWFKAEVHLKDKKLVMVPSIDDIQEVINKAAMDIISASRQIIQWQYKELDNYLELFSKYEHLWQNMRNEEIQTFVSEKRTDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4REN1</accession>
    <name>A0AAV4REN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_519161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007934">
        <property type="protein sequence ID" value="GIY20768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4REN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10692" checksum="8A9DDBE00B5D14C2" modified="2024-11-27" version="1">MRWSKHSHPGMIEAAVSRKNMWRVRVAAVPLGRSGCPSVLPGAPPCPGGEGTGGVQRTRVDDSPPLNTSSQTGFCVWGCADMARRTEIRPYKVDTIVGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPY2</accession>
    <name>A0AAV4RPY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-arrestin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ARRB2</name>
        <name evidence="3" type="ORF">CEXT_16371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008095">
        <property type="protein sequence ID" value="GIY22023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014753">
        <property type="entry name" value="Arrestin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF17">
        <property type="entry name" value="KURTZ ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00309">
        <property type="entry name" value="ARRESTIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY22023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10995" checksum="9DE005FDED8EACD6" modified="2024-11-27" version="1">MDSDDAAKRPGTRVFKKSSPNGKITVYLGKRDFVDHITHVDPIDGVVLVDTDFVKDHKVFGHVLAAFVYGREDLDVLGISFRKDLYLASEQIYPLEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQ02</accession>
    <name>A0AAV4RQ02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_661331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008163">
        <property type="protein sequence ID" value="GIY22547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQ02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18564" checksum="AA78079E4384A8CB" modified="2024-11-27" version="1">MLLNDVEAGLKKASADFGWCISALEGVSWFEIWPTFHHAIRMLLNDVEAGLKKASADFGLCISISLEGASWFEICPTFHHAIRMLLNDVEAGLKKASADFGLCISTLEGVSWFEIWPTFHHAIRMLLNDVEAGLKKASADFGLCISTLEGYLGSKFGLHFTMLYEWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZ11</accession>
    <name>A0AAV4RZ11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_187558_1</name>
        <name evidence="2" type="ORF">CEXT_609921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008619">
        <property type="protein sequence ID" value="GIY26061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZ11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY26061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11718" checksum="AF36ED74C20AF400" modified="2024-11-27" version="1">MLHRTTDASGSLYADIEQKAAKQTEEDFSQFNSTNDLTGDMNRGMAGNVTEVQVYGLDKDAHLSALGVTIAVGCSLIMLNAVVFAAIFYQKDKMNAARNMQKAFYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9I3</accession>
    <name>A0AAV4S9I3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_122541_1</name>
        <name evidence="2" type="ORF">CEXT_752331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009296">
        <property type="protein sequence ID" value="GIY30928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9I3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043427887" evidence="1">
        <location>
            <begin position="18"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15198" checksum="EA9B367977FF2ECD" modified="2024-11-27" version="1">MLITVLVFLLESKPAESPTTFEEREKRLQKEYSCVENLNQERIPPSDTSFLVMRRRSTPAEEASSASVARMSPLFQRPFCSYWSKKKANPTLHINVHRDSPDELVDSPLRTPRLDRYCAKCDIQFASYKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SA12</accession>
    <name>A0AAV4SA12_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_128432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009215">
        <property type="protein sequence ID" value="GIY30352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SA12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="23782" checksum="A08B88A7DA1728D7" modified="2024-11-27" version="1">MTQIARSYNNGDPDNMSYCDNISPLYCAGESNPQHIGLRNHGYANHSPSGPVIESSCAFCTPSTTVLANRKPCYISLGNGIGDVFFFSITRCGVARSNFCGPRVRFDWVQIGGAPSPPGHKNDFISDLPTAVYRVINGLKNIYVVKLPCLIDFFLLIDVLEIDEELKVHETCTENLKNETKTFDPLTNYPVLSSNANITNDISNQTPFHLKTKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE32</accession>
    <name>A0AAV4SE32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_693831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009437">
        <property type="protein sequence ID" value="GIY31945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY31945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10380" checksum="3704C16D72F71DCE" modified="2024-11-27" version="1">MTDTRNKELIKHGASVHITNARREGGTGKGGEEQHEQPNPPAVQRCAANDAHGSDHRRGGIIGMRCRFEWSGNRRGEQLKGPEEKIIVFCCSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SER4</accession>
    <name>A0AAV4SER4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_157521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009555">
        <property type="protein sequence ID" value="GIY32848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SER4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11552" checksum="A332FD5D6C630E6F" modified="2024-11-27" version="1" fragment="single">RKLRSILMPSAQRFHEGTCSLKIDGNSDSPHFFGEEFVFIPYNGQSLRRGSKVDFSRSISQLIDFYELYEYLLFGQRNKAPHYLSIRPNFFLCKAASHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQ29</accession>
    <name>A0AAV4SQ29_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Activating transcription factor 7-interacting protein Fn3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_590432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010061">
        <property type="protein sequence ID" value="GIY36533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQ29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026085">
        <property type="entry name" value="ATF7-int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056565">
        <property type="entry name" value="Fn3_ATF7IP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23210">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23210:SF26">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16794">
        <property type="entry name" value="fn3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activating transcription factor 7-interacting protein Fn3" evidence="2">
        <location>
            <begin position="211"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY36533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="304" mass="35443" checksum="722CBD419C3C1489" modified="2024-11-27" version="1">MEVEDGSLKPMQFRLQPINENFDHMVVDGFSDDESEEYVEMTYKEMQDYIRKKMLEYRKMSENPLIKLEQQNLELIAKIKEKKGKVKELQKSMAFCLKNEIRFYLILGVLPKITTRSIGVSTNLSNNQIHSFKTIVIDYIDLTDEPEGSESDIQMEHPAPFPACFYTHPSKDFLEIPVKPFVKVCVTEKGTFNHDPFLVWLMFLRPNDVFQVYGILLSWNIPSISTFNYMHVEGFELFRYQVTSNVLPSSLFWRQIGFMKAQPLPMRCNVGVFKPEFTYFFAVRASDVHGEHGEFSSPVCLRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQM5</accession>
    <name>A0AAV4SQM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_330701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010079">
        <property type="protein sequence ID" value="GIY36713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8570" checksum="241D618F7D72D1D2" modified="2024-11-27" version="1">MPILLSIGLIEAINLQSTSQTTMNLLAQHKSSHVIKNSHPTSKSQASLNALSVENEDSSRGFQTEKMYLEIPRAALTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUE0</accession>
    <name>A0AAV4SUE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_124431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010018">
        <property type="protein sequence ID" value="GIY36177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12132" checksum="1E44AA5FE2CC48E0" modified="2024-11-27" version="1">MRGTMLHLLGPLRLLQPIQYVKSQSHKMRAAKNHFLVEPMIMSPVDIAALIKDLMIYHWAKQECPQAIDDPLTKAKIRTENAIMCQQTLVGCNMCSKIICKLLRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZD9</accession>
    <name>A0AAV4SZD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">snRNA-activating protein complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SNAPC1</name>
        <name evidence="2" type="ORF">CEXT_382621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010294">
        <property type="protein sequence ID" value="GIY38381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019188">
        <property type="entry name" value="SNAPC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131">
        <property type="entry name" value="SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131:SF3">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09808">
        <property type="entry name" value="SNAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="367" mass="42808" checksum="5FEA951E8D608170" modified="2024-11-27" version="1">MKPVAAGFKEDAENLRKEFIDKHSLEFSDFAAVWKSHNFSIIYLYSDNLELTQFMQEAFQLTLKYLPSSLLSDKCFAVYLLYALFKNQPLEPPIRVRVTQSEYNGIRQIKTDVHHGCKSLHYIINYMHAHGFDFVRHSTLHGPLNLRNSQHREKNSLNDVLRSKNGFMELCASDILTEVQDLRKKYAETKAKLPYNVKRSMDSLIDFIKPDERFQIINYAERLNVMNKEEVSEEGNTVTSHCMELGTKSNIGFRRAKLKVQSFESQARFKQLNDSSSDSDSEIEFVEISQPKRKRGRPRKKVEKRAHRKKPLEKRAELENDPKYTPSRRGRLAKIDYCTYYEMDPGFSHHSLSQNTKESKSSEESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4Y2</accession>
    <name>A0AAV4T4Y2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine-protein kinase 1</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PIM3</name>
        <name evidence="18" type="ORF">CEXT_747961</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 20">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01010699">
        <property type="protein sequence ID" value="GIY41239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4Y2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14005">
        <property type="entry name" value="STKc_PIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000708">
        <property type="entry name" value="serine/threonine-protein kinase par-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000547">
        <property type="entry name" value="Serine/threonine-protein kinase prk-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017348">
        <property type="entry name" value="PIM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051138">
        <property type="entry name" value="PIM_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22984:SF25">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22984">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037993">
        <property type="entry name" value="STPK_Pim-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="33"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="39"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14 15">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR037993-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR037993-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY41239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="320" mass="36800" checksum="D79868B75AB14AF4" modified="2024-11-27" version="1">MLSRKIPAFNMFSSPNVVAPITVREKDPFEIRYRVGPILGKGGFGTVFAGTRIRDNIPVAIKHVEKKKVTEWGQINGSQVPLEICLLRKVSHIKGVIKLLDYYERADHFIIIMERPENAKDLYDYITEKVFLDEKLSRVFFHQVVESVIECHKAGIIHRDIKDENILVDMKNLTLRLIDFGSGAFLKDTMYTDFDGTRVYSPPEWIRSQCYNGHAATVWSLGILLYDMVCGDIPFEEDEKILRADVRFKKFLSFECKDLIRKCLSIRPSDRPTLEEILQHPWMTMPLDNLPSPSIPMRHSARIEDCFDLNSSSGSSQESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5C7</accession>
    <name>A0AAV4T5C7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_525191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010538">
        <property type="protein sequence ID" value="GIY39965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5C7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11561" checksum="2E7C0CB6817E0805" modified="2024-11-27" version="1">MKDHGNHKYSRSKAKQKKTLKNCIDTEIAIWAVKGRSIEELTWLRRRISNRMSSLQERLALSFLRTSALLKKAPLSLADNCQPSEIGLSTAAKKAPESDCQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGF2</accession>
    <name>A0AAV4TGF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_301641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011198">
        <property type="protein sequence ID" value="GIY44804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12704" checksum="7E5B230A340AB4A3" modified="2024-11-27" version="1">MGNERMDLLTEKRALETQKPTRTSSFHSTKNLTNMTFKHIFKSETEETFKVNNWEILTWTPLVCLMSQEKLLSQSLDLINHDCLKFPLFRIDITITPDCTLCNPSQPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGG6</accession>
    <name>A0AAV4TGG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proteasome maturation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">POMP</name>
        <name evidence="3" type="ORF">CEXT_590441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the POMP/UMP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011049">
        <property type="protein sequence ID" value="GIY43887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008012">
        <property type="entry name" value="Ump1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828:SF3">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY43887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13405" checksum="ABC0EB766C8F50F5" modified="2024-11-27" version="1" fragment="single">MDLPSLKPRPDVADKVQIKETGDFSAYDTMTNGFMSVRGQLCNSHALEQTERKSNQENMRLAFLRSTQGIHAPLKIMHEKNAVRKTQRLPFLPSSNIALETLEGRDEFIDFDDYIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKH9</accession>
    <name>A0AAV4TKH9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Metalloprotease TIKI homolog</fullName>
            <ecNumber evidence="13">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">trabd2a</name>
        <name evidence="14" type="ORF">CEXT_433651</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">Metalloprotease that acts as a negative regulator of the Wnt signaling pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="13">Divalent metal cations. Mn(2+) or Co(2+).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the TIKI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="13"/>
    <dbReference type="EMBL" id="BPLR01011447">
        <property type="protein sequence ID" value="GIY46609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040230">
        <property type="entry name" value="TIKI1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31120">
        <property type="entry name" value="METALLOPROTEASE TIKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31120:SF6">
        <property type="entry name" value="METALLOPROTEASE TIKI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 13" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU369069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY46609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18426" checksum="BCC269A5D99D57E6" modified="2024-11-27" version="1">MPRGIRFPVGLDAGRGCFRSRDWGFESEMSSSPSPLSLLFVFLEFVIVFVLFALNQTLVRLEELRNGRPSPFYGTEDLVRHYNCRNITSASFTNPDVLSDTGNATDELLSSDINRYFRQELIEKRNARMAHRVLQLLHQYPDESFFFAFGTGTLILIVQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TLE7</accession>
    <name>A0AAV4TLE7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_11317</name>
        <name evidence="2" type="ORF">CEXT_420181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011572">
        <property type="protein sequence ID" value="GIY47398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TLE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11140" checksum="A5F96603D2ED1395" modified="2024-11-27" version="1">MPDCRSLSRTSAVVDSPWEDDSVHDDEGAKDCYEARLIVRGVDGSDSRKYTLNVENERGSEAFAVALEVRGPRNVPATTNLKEEKVLVLVFYPVLSTAVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TM07</accession>
    <name>A0AAV4TM07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_781121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011599">
        <property type="protein sequence ID" value="GIY47603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TM07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10250" checksum="4637F36365C0E51B" modified="2024-11-27" version="1">MTCQKTIFSLHVVEADAALPPELNLLSPTSTRKLNAVQMPTNMYRVPEKSKFKRLKTEAQQQPVSTDSQQQQPVSADSQQQQQQAALFSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNS1</accession>
    <name>A0AAV4TNS1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cyclin-dependent kinase</fullName>
            <ecNumber evidence="3">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CDK9</name>
        <name evidence="12" type="ORF">CEXT_433781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01011447">
        <property type="protein sequence ID" value="GIY46622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000124">
        <property type="entry name" value="Cyclin-dependent kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF233">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="32"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY46622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20115" checksum="A6737675247D0574" modified="2024-11-27" version="1">MVKSQSVSPEKEKKSQKKENIRYPFCDDVIKYEKLMKIAQGTFGEVFKAEHRVTKKIVALKKIKKGSVNEGFPITVLREIKILKFMKHKNMVHLIEVCRSEGDPIKRILPSFYLVFEFCDHDLSGLINNTDVTFTLGSIKMVMQQLLNGLFFLHAHHIMHRYPTTKADAYKSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U182</accession>
    <name>A0AAV4U182_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_132851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012114">
        <property type="protein sequence ID" value="GIY51474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U182"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8908" checksum="E518E34E1C416C06" modified="2024-11-27" version="1" fragment="single">RTGLRTPQMRSDEIRKHNGMDKTIPICWTTFRACPFCDGLYQTLDAEDKKRRNLSKKKMHIGIIKREYRPKQWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U630</accession>
    <name>A0AAV4U630_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_389621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012339">
        <property type="protein sequence ID" value="GIY53254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U630"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13854" checksum="F7B34615C19F5D00" modified="2024-11-27" version="1">MKKILLVEICLCSQSTENIRTESNLDNYPCKCLNRYVKSEGFFVTLQCILLVITAVALDLRHFRLPEYDGLPCAIHAQPTKGLLTLLVMEEIQQLGGTLEICKTYGVMVLFCWEMASELHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAP0</accession>
    <name>A0AAV4UAP0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-carbonic anhydrase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_502921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012555">
        <property type="protein sequence ID" value="GIY54785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19207" checksum="2B9C978CCA343BB7" modified="2024-11-27" version="1" fragment="single">VSGVLSNTGHSVAFRISDVQPSNPINISGGPLSYKYRFHELHLHYGRTDDRGSEHTLSGTAFPGEVYYVPLSVELTGGPQEARHLQKTDMCIKYKLYRKMQFGNFFGNLSTTSGTTVSRETVFRHPRKESSLCLAANGTCMLYHIAEGNPSFMLLRTPFLNTVRSGSYPLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UEM8</accession>
    <name>A0AAV4UEM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_198351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012745">
        <property type="protein sequence ID" value="GIY56227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UEM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10491" checksum="BA84DAF64AE3973B" modified="2024-11-27" version="1">MLHYKNKTAQGTKEVFCGHLPGDLPPGDGDAAGHPPVLRGVEPNEKEIKPKYSTGSPFFRAGCSYACVEQNFNSWTADAGENCLGYYSTTHPEQNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UGM2</accession>
    <name>A0AAV4UGM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_656401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012820">
        <property type="protein sequence ID" value="GIY56855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UGM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8290" checksum="ADBFBBDEC60DE60B" modified="2024-11-27" version="1">MNSGRKKGEGFSLWALLSFPFYISSFYSYAPKDRRVDEINSSSLGGTPAVTSLPSHPPFKNSDDEKMAILEIFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UI53</accession>
    <name>A0AAV4UI53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_761571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012907">
        <property type="protein sequence ID" value="GIY57433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UI53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16340" checksum="FBDE9EA087137C6E" modified="2024-11-27" version="1">MVLKEDIPDSITNSITSALDLDNGTFSNKPPSLQPFFEEDWIGSCSSAKSPLTKDSENLNAVSIAEVSETLLENKHHSNVNKVEEPNSNSLVEYNVSSPNEVFPSNVEPPSTDTDSNHIETTLGSITNYLLEDPFDKFTDALISFFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UM83</accession>
    <name>A0AAV4UM83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element tc3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RF55_24064</name>
        <name evidence="1" type="ORF">CEXT_592841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013145">
        <property type="protein sequence ID" value="GIY59006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UM83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326:SF1">
        <property type="entry name" value="HTH PSQ-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326">
        <property type="entry name" value="TRANSPOSABLE ELEMENT TC3 TRANSPOSASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="27621" checksum="36DE3EEF0DF3A91C" modified="2024-11-27" version="1">MNNSKTNQDTKIRFAPNGWKRNRVLCGNKKIVLLATNRWRCRISDVGLCKATSDIKKKQLQQNSESAIAALRAYRYMKGMRDSKGPITSSALKKMLKKFEATGSLASRQSGRPSTAAAVATTVVQTVQSMAAVAAHGECNAREVSRQTGVSYRSVWKALRITLKRYPHKLQHKQELKPPDFDSSRGFANLVFNKMEEQHDWLHTVLWTDEAHFTLSGAANTHNCRVWTTENPHAFVEVPLQQPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNM5</accession>
    <name>A0AAV4UNM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_802001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013205">
        <property type="protein sequence ID" value="GIY59455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11772" checksum="F50DCD229AB59A88" modified="2024-11-27" version="1">MPGRKQVIRYRTDGQDEGKTFLKTVVVNNAEKKNSRACFSSKKHSKAKCPGENKIIGYRTGGQDKGEEVEKINGPSFCEKLMKGRKSGRFSDVPVARIQCYSCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT78</accession>
    <name>A0AAV4UT78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_781551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013414">
        <property type="protein sequence ID" value="GIY61007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11878" checksum="06C17C087C5D5565" modified="2024-11-27" version="1">MPPQTVIISWVIPECKVIAIACISTESCFYADLLFLVDVFQPHSACSVHSIENNTDLKLQKERSPCSQPRILKPGCSSLCCFLGSICGIFFACFVRSLTPVLLQFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY10</accession>
    <name>A0AAV4UY10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_345731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013641">
        <property type="protein sequence ID" value="GIY62611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25357" checksum="22951A8F154B35ED" modified="2024-11-27" version="1">MSVVGCEIGRRQDKIWPDILGSGIGWDCVRIPLKLNLMVFGLGSRWPDQYTLFNNKINSDIINFKDKTKATLSVMERDTLLQHSTIVNYLSNHPSIHPNFLELQNRIPTMTPSRKQTSCTRERGKEMEKKPQKVPLPISSIPGQNWRGQTSRIFDREQKVPFPEFLERKREALLGPFHQLFRDPWDASRSERCDCSAVVIGFNRIQPTKVEQCGISIWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBF8</accession>
    <name>A0AAV4VBF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_172841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014232">
        <property type="protein sequence ID" value="GIY67378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8228" checksum="BDE8B2DC2042A29F" modified="2024-11-27" version="1">MPIYRPQQQSRARCPPHPERRCRRFFTGHSMAAQLFHYDNFAERPFAQAGHVPIVNKAYRRGEGGLSEDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VD02</accession>
    <name>A0AAV4VD02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_417981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014337">
        <property type="protein sequence ID" value="GIY68182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VD02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11675" checksum="F0C1CC095ED78BC4" modified="2024-11-27" version="1" fragment="single">ARLKGRKVGRKQEGSRGTKRKALGDHEGELQVREVDDPGKSISFIVHCNVLNRNKVTFIFEVAQLPAKYNHREIPQTSTINSQINMESEPAASSGVILLVTFPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFX2</accession>
    <name>A0AAV4VFX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Tkt_1</name>
        <name evidence="3" type="ORF">CEXT_224221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014438">
        <property type="protein sequence ID" value="GIY68774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051424">
        <property type="entry name" value="Transketolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43195:SF1">
        <property type="entry name" value="FI06132P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43195">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY68774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11227" checksum="AE6BD84FDC3C0BCC" modified="2024-11-27" version="1">MLVTKLFLANRWRYEHLLNIENKEGWHGKPLGTQGTEIIKQIQEELLKKGMDTKLERTAPEEEIEAINFSDMKLSEEPSYVYTEKVATRLAYGTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGW9</accession>
    <name>A0AAV4VGW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_95491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014443">
        <property type="protein sequence ID" value="GIY68793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18515" checksum="06E80EC70ADF03FE" modified="2024-11-27" version="1">MSCVHPSRFRITFGTDHSRPKVTRGQPSGSGWFRKFVIFHHFFVIHLKVSGQSFPQSHDENTTYALFGMTVQITHPWQNKISASRNTEGCIIKISQKMTAAGFISENYEPDFQRSKLTFNTCLDCSSNSRYTFALFVRMPYGLLTGIVPANFKRPYGKYNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VIX8</accession>
    <name>A0AAV4VIX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_467871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014595">
        <property type="protein sequence ID" value="GIY69826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VIX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15149" checksum="18B00E47247CD724" modified="2024-11-27" version="1">MELEDAEGNGLFQVPLEVPLQSSNEISYIEKEKTRCQEITTTQADIKMLETQLAVPHDWNGTAKDVAQRHYQMRQYLTDMLTQQRKKLSSLGSCSLINCPKHAINNSVKPKRNSNHLTSNNLSIDGFQYPNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLU7</accession>
    <name>A0AAV4VLU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_47451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014673">
        <property type="protein sequence ID" value="GIY70488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14118" checksum="7F4554997EFE9EB3" modified="2024-11-27" version="1">MGGNSVTSNLELHSNALCTTPTRDCRGRTHAGDCFLCVLILNGKPERQTLIEEKPHSLVDAHNQSAPLNTSPATTCSVPQSGFSFYLTLPPFNASTKHQPTVPRTLLNSSCGKHTQCFASDKACDMGIPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMS3</accession>
    <name>A0AAV4VMS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_218650_1</name>
        <name evidence="2" type="ORF">CEXT_573251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014837">
        <property type="protein sequence ID" value="GIY71650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="231" mass="26419" checksum="2FB2FDBD08835FFC" modified="2024-11-27" version="1">MPNSKNCSCEVGDVDSCQVMQDVKNSIYRLNDILSSSFVPSLGNTVISGFNQPTSNYSGSLQSFYSQFRQLQEKQRINELKHKLQNESRGQHSRILDTRDRNYSADFTRNDSSGFNHALNSNVYTINSSDDPINRARNLVLREQARSWKQQQQYLSSSDMQGFLPSERNYIGSRSDNISPSPSSRISSGLSEHSSTNLPFLKFEPDAETEYNEWMSRLKTLQDKIRSHKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VQT4</accession>
    <name>A0AAV4VQT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intraflagellar transport protein 27 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IFT27</name>
        <name evidence="3" type="ORF">CEXT_184511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014926">
        <property type="protein sequence ID" value="GIY72294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VQT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY72294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18807" checksum="CC0D7BF4A835A113" modified="2024-11-27" version="1">MPNILRAKCIVVGDPAAGKSAIIHTFLHDSDKFQKNYIMTCAVEIKTKIIAIPDTVDAVELLLFDSAGKDTYLDFQSQLWHHPSMVCVVFDLTDENSFNNSSKWLDIVRNTGRYLTVPGVLIGSKSDLKERRVVKASVAQEYARKNNLQYFECSAKENKGVEEPFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VX73</accession>
    <name>A0AAV4VX73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_344001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015230">
        <property type="protein sequence ID" value="GIY74559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VX73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12314" checksum="90B241436724F449" modified="2024-11-27" version="1">MDARDGCSYSKLTRRDMCAAIHCWENIQMTCDTAVHGRWPAPVQVVHARTCILIRAEGLWVNRRAIRHWQESERGFKWRVLEELGWGGTRRNQNVFECDKWNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6M5</accession>
    <name>A0AAV4W6M5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_165588_1</name>
        <name evidence="3" type="ORF">CEXT_320781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015594">
        <property type="protein sequence ID" value="GIY77253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6M5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043450360" evidence="2">
        <location>
            <begin position="21"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY77253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14870" checksum="566DBA65CE69A072" modified="2024-11-27" version="1">MFISVFNILASLFWYGYSFAFPPNAGNVTNMCFAIGFVQYLVLLFITLSPAAAANQAAAMAREFVLSLPGWFPKRYGIIKVHVRREFMHKTTLTLWKIYRIDYSLIISAIGSLISYGILVGTLGSVQNSNKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7Q2</accession>
    <name>A0AAV4W7Q2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_628451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015794">
        <property type="protein sequence ID" value="GIY78772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7Q2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9447" checksum="BF3052450A8C1B77" modified="2024-11-27" version="1">MEPPARLKVRSSPPDGAISMIQSMERNFPGKLFTSINLPMEQSSRWSHQHDSNSPQMEPSAYSKHEEDLNLKMRRLPTTHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W966</accession>
    <name>A0AAV4W966_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_486872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015837">
        <property type="protein sequence ID" value="GIY79031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W966"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9633" checksum="7E980CD1D46956A3" modified="2024-11-27" version="1">MLSGTPPVAGCCSVRHGLFSPSSFRGLFYDQQVRSIRCTCFSQHLEGGQLKGRPGDDIEDMPNMLSYLRKTILVEEKKKIDQGNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WE97</accession>
    <name>A0AAV4WE97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015975">
        <property type="protein sequence ID" value="GIY80149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WE97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9681" checksum="E348EEAC5F0B614F" modified="2024-11-27" version="1">MEKLNQTTILMTIPFLGLSLSVTSNPLLLVDIRTTCARPGILQTIRTKGNINCPHQFRFESSFQKTRPVTDKVDLDPRFMEGFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPI3</accession>
    <name>A0AAV4WPI3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_811411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016436">
        <property type="protein sequence ID" value="GIY83851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10337" checksum="4A90D980DFD40619" modified="2024-11-27" version="1" fragment="single">RGPAFEYEPPSQIDFDNSTGAVAVMHGQKVNQCRTSGGRPRMDRLFVKSFPGVQHLRPDGSMVFAPFTPIQYRRKSTMQYTDASQLMWLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WR58</accession>
    <name>A0AAV4WR58_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_30161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016623">
        <property type="protein sequence ID" value="GIY85182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WR58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585:SF1">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46585">
        <property type="entry name" value="INTEGRASE CORE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="17121" checksum="5B8A3EFE2267925E" modified="2024-11-27" version="1">MSLEKFYKNPKEPASFGGINALRRAVGKQVKTKDIKQWLETKDSYTLHKPARRNFKKNRVIVGGIDEQFQADLLDLQSIKQFNNGYKFLLTCIDVFSKYAWAIPLKDKTGQSILKGFQKYSKNENQSLCKQTKVQSSKIKLCKNILRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WR97</accession>
    <name>A0AAV4WR97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_271141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016515">
        <property type="protein sequence ID" value="GIY84455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WR97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8148" checksum="774F6C629EB7FB6F" modified="2024-11-27" version="1" fragment="single">EGDACKLIVSKHCEEACRYINWVYFPLRVEFVEKRMFCELNASGVNRVTFILALILNLGTSIRLTISNPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WU94</accession>
    <name>A0AAV4WU94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_212341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016734">
        <property type="protein sequence ID" value="GIY86072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WU94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13639" checksum="D1CD02523760AF58" modified="2024-11-27" version="1">MTIDLTNQRNMRHPPNELSRVLQTSSTKIKNGCIREKAIRRGHAGSNGQPWHSVSQRSFSPFLVSFTLSLARKHSAIDPTPCLTLTREDEEFGRLLPDFDLATLSESENEMVRDTGISLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVA8</accession>
    <name>A0AAV4WVA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_199221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016659">
        <property type="protein sequence ID" value="GIY85473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9834" checksum="21EEDE3FDD502B92" modified="2024-11-27" version="1">MINGLCPPLSPGKEGESSFLPSCDSAVNSTPKLLRDKIPRGKKPRLETSFPSTVLRCERIVLEESFFRWSWRFIKRNTNLHSKEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2V2</accession>
    <name>A0AAV4X2V2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_556331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017022">
        <property type="protein sequence ID" value="GIY88099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13675" checksum="B7426A7A1F8639C1" modified="2024-11-27" version="1">MAAFSSILQSGIVFSLFHSIPCLPFPDEARTETPFSNRLICRRHHVLGHWHVRISPISCYPGGTFTYRRSLGRAHSRQLVRHLFPFVFHLLRTVGSATKHFLKPKVIGEMLFQFRGTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X388</accession>
    <name>A0AAV4X388_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_103241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017226">
        <property type="protein sequence ID" value="GIY89592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X388"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="7779" checksum="F18B13DF24411D28" modified="2024-11-27" version="1">MNSSTHSGSEALDIFEASIESSFSPVCHRTRSQLAAKELFGVRQVGAPSGALLDSFRSASVDSMVDRGCPDCNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7J3</accession>
    <name>A0AAV4X7J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein yptV1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">YPTV1</name>
        <name evidence="4" type="ORF">CEXT_685811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017383">
        <property type="protein sequence ID" value="GIY91117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001329">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY91117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="203" mass="22502" checksum="6E65C9958F349B51" modified="2024-11-27" version="1">MKEDCPINIVVLGDMGVGKSALLLRFANGTYKPHIPSTIIDTLPAQVIVKNKLVNLTLWDTAGQERFRALVYHYFRRADGVVLVYDVTDNESFSKLSSWAADLKAINQIASVIIVGSKIDESSRKVVSSEAGKAFADNQRADFIEASAKTGENVDEIFHRLALKILLSKESPETFSPLTRKNSELTLHNSNSNRTTDKKEKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9A3</accession>
    <name>A0AAV4X9A3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monocarboxylate transporter 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">X975_01524</name>
        <name evidence="7" type="ORF">CEXT_689711</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017327">
        <property type="protein sequence ID" value="GIY90541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052983">
        <property type="entry name" value="MFS_Riboflavin_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43385">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER RIBJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43385:SF1">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER RIBJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY90541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10663" checksum="1A5B2DD5C61B6D0B" modified="2024-11-27" version="1">MSAGSMLVRLPVLVMKHVKKEEHSVAMGCYGFASGLVPLGVPSLIGHFRDNFGSYDGMYYLLGSLSIVSGAFWLLEPVLVRLKERMEQRRDDGMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XI71</accession>
    <name>A0AAV4XI71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_323701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000443">
        <property type="protein sequence ID" value="GIY94857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XI71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9374" checksum="A85FEB3523DB8ECA" modified="2024-11-27" version="1">MAVRGKVGRNGHNREEWLARDGMAKIEGRNGRWRAGMAIIRGRKGPVEGWEWPNRGKEWLRKREGLYITGMMATLARRNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP70</accession>
    <name>A0AAV4XP70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_162841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000623">
        <property type="protein sequence ID" value="GIY96128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10979" checksum="1FCBDB4541F4BD04" modified="2024-11-27" version="1">MVTLKGCFWPLLKRGRFIGEDGSAFVQKPSLPRGPERFIALWLECGFCSAPEKEIERVEMRRNATARDDYTFRGDGMAVSAFPNFPFGLAVSAVICLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQC4</accession>
    <name>A0AAV4XQC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_170071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018137">
        <property type="protein sequence ID" value="GIY97241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7923" checksum="CFFB4629C46DE077" modified="2024-11-27" version="1">MILQREIWLSTSFESPDDPIYPKVGMDTKVDIGVTKVVNSECFDCLKAKDLNVWSDEHDDDEHEHDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR94</accession>
    <name>A0AAV4XR94_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL9</name>
        <name evidence="7" type="ORF">CEXT_553351</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000821">
        <property type="protein sequence ID" value="GIY97701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="6">
        <location>
            <begin position="7"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="6">
        <location>
            <begin position="53"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY97701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16547" checksum="019C8B432AEE3981" modified="2024-11-27" version="1">MQLLGKDKLVVQKWFGIRKELATVRTICSHIENMIKGVTRGYQYKMRSVYAHFPINITTSKDGSLVEIRNFLGEKILRRVNMQPGVVCQNSTQQKDELIITGNDIELVSRSAALIHQSVLVKNKDIRKFLDGIYVSEKGNVVAAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUY9</accession>
    <name>A0AAV4XUY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribitol-5-phosphate xylosyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rxylt1</name>
        <name evidence="4" type="ORF">CEXT_8301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018201">
        <property type="protein sequence ID" value="GIY97710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120053">
        <property type="term" value="F:ribitol beta-1,4-xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21099">
        <property type="entry name" value="RXYLT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055286">
        <property type="entry name" value="RXYLT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057538">
        <property type="entry name" value="RXYLT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057539">
        <property type="entry name" value="RXYLT1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15576">
        <property type="entry name" value="RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15576:SF1">
        <property type="entry name" value="RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24785">
        <property type="entry name" value="RXYLT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24786">
        <property type="entry name" value="RXYLT1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="RXYLT1 N-terminal" evidence="3">
        <location>
            <begin position="107"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RXYLT1 C-terminal" evidence="2">
        <location>
            <begin position="253"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY97710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="445" mass="51515" checksum="5CB7FE244EA58C22" modified="2024-11-27" version="1">MLFSLRTVTIAVFIVYCVLTCYTGYILLRNNNHVKDGVQYTHRKLSLPDDGEDWNPWGEEFEREKKTFIFQKASPIKLLTNQSLDLRKQLTKYAKFDASQSSESYNVEIWGKAAIGLYLWEHILGGGKLENKMDGLWSYGFKRLDNLKLKFRTGPGVIPSKAPSDVQHLILILNGRSDDKVTFAKMWLDFLPQFRNLRSVILIILGNEQCHNEWLIPYMTKSGGMVNKTFLVYDSPLVDNVNFYQWPLGVATYRGFPKVDSRKMDLENSRPYVCNFLGSIYPHSSREKLMNVLESNNLTQFCFIKARYEWQPKETKNSLSIYIQSLHLSDLTLSPVGMNTECYRIYEAMSFGSVPVVENVMTPGICGDSKALIGSSPLRLLKSLNAPIIYVNDWSQLPDIISRELQMPLEEKIQRRIKIVEWYENFKLQIRENLLSVLKENILRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVN5</accession>
    <name>A0AAV4XVN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001019">
        <property type="protein sequence ID" value="GIY99186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="18311" checksum="19300CAB7C7CADBB" modified="2024-11-27" version="1">MSGTLRVMRYRMKTLITSNHHRVYPFRLLKHFENSDCASGIEDPAMAFFTAADTRALKTVEQPCTNNSVFMQHCPNLSFYNKLPPNCPRHSNYLTIYDSTDQYYKASMNMQSRQSAMQDLEIYRFQDTEYDAMGIVRKSDRREENTNFASDLNCTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWY8</accession>
    <name>A0AAV4XWY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_613701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001026">
        <property type="protein sequence ID" value="GIY99257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="30671" checksum="DAE3548C46711FCD" modified="2024-11-27" version="1">MRRQSERDPFATTCLRILVLRWGEKSTLPVSFVYLAECRSEFGEGLLRIRVCKLDYFSSMDDVVRKEIASLELSMKHKESRGIIEGIHDGYPSEAEYIQKHPFCIPKVKRTTIFITFKQNFIPQKRIHIIYIVAEKDCLTRLRNAIQSGLEMLSSSSKWYCMRLGYVWMKERFAEDVVRKEIVKASILHPKGKASKIDAFSMTALLVPTWARGCTQGAERKKEEITNRTNKNCLWKPDLLLLLCFLFFFSVAVPSESIVCEKQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ24</accession>
    <name>A0AAV4XZ24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_493901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018460">
        <property type="protein sequence ID" value="GIY99793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12531" checksum="39C0A494B4D45D6C" modified="2024-11-27" version="1">MVVITIIRTPTLQNILAAGLIVQMLSHHGHHKHHHGHHHGHHHHGHHHHESRHHPNFAHFQHQESRIPPNAFAMQPNPWGYHPQMNLDSLPLSSMSKHWGFQCSGSISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y089</accession>
    <name>A0AAV4Y089_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_7811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001164">
        <property type="protein sequence ID" value="GIZ00518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y089"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="231" mass="26651" checksum="E6BE9B672CA30B87" modified="2024-11-27" version="1">MEETATVLVTSEGCCPKETEHPVVQSSTVAVQTTSNDLVVENGHHADQYEIASNLENVRMEVDVSSQESVMDISSQESQTGVIDTKPDYQDSGNHSLSDNIQTVRRSPVPRKEPLPRKVQEKEEQAVPKQGEELALSKWEEELEMREEAIRKQEEVLALSTWEKELEMREEAICLREEDLRFREEAICRREEELRRREEAISSREIKIRKRITYADYSSSAKKRKCKNNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1C5</accession>
    <name>A0AAV4Y1C5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exocyst complex component Sec8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Exoc4</name>
        <name evidence="1" type="ORF">CEXT_157191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018459">
        <property type="protein sequence ID" value="GIY99780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1C5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="242" mass="27866" checksum="C2260745521BE060" modified="2024-11-27" version="1">MLESDLSDTEGLKDLRCELHRLLDKLYSIFWRNLLRSYTCPLFISCFKEGTIPALKRLLMKRCSCCPIVKNSTKSINFNIQYVKSLLECMTLMGKIPETLEILKEECQNELMKIVQKLSKYLHDIIQKSTDTPLLELPMKQGQVFLIDLLETIIGHFRQISINNKIFLHILGKSSFYGLDDTSYQMADVYSNIQVTIEYFVANYLETQPVTTLPLQNISVFSNSQNISDLSDFFSSSELCGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y933</accession>
    <name>A0AAV4Y933_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tissue inhibitor of metalloproteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Timp</name>
        <name evidence="11" type="ORF">CEXT_144571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protease inhibitor I35 (TIMP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018837">
        <property type="protein sequence ID" value="GIZ02649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y933"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008191">
        <property type="term" value="F:metalloendopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002020">
        <property type="term" value="F:protease binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051045">
        <property type="term" value="P:negative regulation of membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03577">
        <property type="entry name" value="NTR_TIMP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.370.10">
        <property type="entry name" value="Tissue inhibitor of metalloproteinase-1. Chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001134">
        <property type="entry name" value="Netrin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001820">
        <property type="entry name" value="TIMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008993">
        <property type="entry name" value="TIMP-like_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027465">
        <property type="entry name" value="TIMP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11844">
        <property type="entry name" value="METALLOPROTEASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11844:SF25">
        <property type="entry name" value="NTR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00965">
        <property type="entry name" value="TIMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00206">
        <property type="entry name" value="NTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50242">
        <property type="entry name" value="TIMP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50189">
        <property type="entry name" value="NTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0481">Metalloenzyme inhibitor</keyword>
    <keyword evidence="4" id="KW-0483">Metalloprotease inhibitor</keyword>
    <keyword evidence="5" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="NTR" evidence="10">
        <location>
            <begin position="45"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared with metalloproteinase partner</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="45"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="47"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="57"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="164"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601820-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601820-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIZ02649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="234" mass="27114" checksum="244319B80EB59008" modified="2024-11-27" version="1">MNEIITFRERFSEFDLRVWKADGYYDGLILGVLTLCFIVGEVELCSCFYSHPQEHYCVADFVAVVRVKSQGKGDSGITAYHIKVKKEFKMTEKARHALSQGLIWTSSNEAACGVTLQPTRYLIAGRIRGEKPFVSLCHFVQEWAKLSPKQKKGFRKLYQQGCRCRVRMPSFVKNRREPYCSWETFLGKNDCQALYSLCVPTSQTSNGTDECSWVSTAQYRRCMKERKYEREMEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YC36</accession>
    <name>A0AAV4YC36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_333821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001639">
        <property type="protein sequence ID" value="GIZ03727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YC36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16342" checksum="5C19B5A1A6A7DF36" modified="2024-11-27" version="1">MTQMSWPIQPITCLNDLQPNPSGFYGRNNHSFSPKPYISELLIMFYGTKPLFAPLQRFNGGMDDHSYLAAIRPRGREEGMEPLSQEGRPLVLHSAGEKIAFHHPLICIEAASVVGITPLETGPPKLPDPLSSSWIATRHFLIKGMFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCP5</accession>
    <name>A0AAV4YCP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_306811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019151">
        <property type="protein sequence ID" value="GIZ04845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10463" checksum="778046C976BBFAA0" modified="2024-11-27" version="1">MSRSGRDCDLVSPEVFLQIFSNAMQIYMTMFPEGLSKPYRLFSSPSSQSLQVYDSCGHKELAMRYMTELFPIMKSGSLECSDLKDNSSSVIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFP7</accession>
    <name>A0AAV4YFP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_494301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019200">
        <property type="protein sequence ID" value="GIZ05079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11812" checksum="84168B2330B43EE8" modified="2024-11-27" version="1">MWVQWDISFVTHSGSSTSEAEKSHQHVSIQILVGDSSRGTVNSQSIKSGRPPDYLSRGHRQSTDHPSPPIRWGGCKDIWRNGIPSCPAVLPPKKIMNEEGEDIFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7T2</accession>
    <name>A0AAV4M7T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane protein 50A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Tmem50a</name>
        <name evidence="8" type="ORF">CEXT_695951</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0220 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019489">
        <property type="protein sequence ID" value="GIX68424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007919">
        <property type="entry name" value="UPF0220"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13180">
        <property type="entry name" value="SMALL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05255">
        <property type="entry name" value="UPF0220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043416596" evidence="7">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX68424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11472" checksum="AA9B25DB5CBCB501" modified="2024-11-27" version="1">MLIMFVVSLELLLFFMINAVSNGQVRGDAYTTGCLGQRGARVWLFLGFVLGFGSLIGSCWILFGLYVIPMKVPQGPGVAVFLQNIFIFLGALVFKFGRTEDLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9Q0</accession>
    <name>A0AAV4M9Q0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001976">
        <property type="protein sequence ID" value="GIX68565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9Q0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13358" checksum="B8A558E599AF8DA2" modified="2024-11-27" version="1">MTSLFKASSSLLSPIAPLVTAMNSKTDAQNEPIINIKTIVGWFNVWPSAMALNIRKNAPMLDTTKDSVFLEKAASTISTQSTTRLKFSKYFCIEIELTLLLPINFSSDLRYLRTPSLKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKW1</accession>
    <name>A0AAV4MKW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_428841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019862">
        <property type="protein sequence ID" value="GIX72604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9127" checksum="ECDC89ED95FFBF0D" modified="2024-11-27" version="1">MISPAGGIPAVREIMVMEVEKSMRSFEDGETERNGALKCFSGRLRACWNELKLGLEIPSAQISERRICAPPTIYRNSGRQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MP29</accession>
    <name>A0AAV4MP29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_161551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002484">
        <property type="protein sequence ID" value="GIX74191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MP29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8978" checksum="BDB95AAD68B1D3C5" modified="2024-11-27" version="1">MWVGGGWISPFRALVEMNVKACQQPHLKVFADEAKRKGRVNGRYFFCVSFLQAGRIFRGMNMFEYMNVYVKFRVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRL8</accession>
    <name>A0AAV4MRL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_176781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002557">
        <property type="protein sequence ID" value="GIX75076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14048" checksum="86D20003A7EBEE04" modified="2024-11-27" version="1">MLASGETSCVASDFRCGTPPHTIALAVYMELTDITEKSRSILQKNVSAKSLKASIQLPHFIFHVLRAIIFHEHNARSHIMFNNASSIPACIFALDCWLFPSVSFEHFRSMPVTVSECVESAWNGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MV75</accession>
    <name>A0AAV4MV75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_182531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020249">
        <property type="protein sequence ID" value="GIX76402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MV75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11617" checksum="33B2D67D28891884" modified="2024-11-27" version="1">MYRASQNTSRYRNNATQIPNATATATSGSNHKYCRGSAAFEIRFPSSIPEEGNRKFNCWIRHELFIGEIFCYIIFPSRENTLNGCFQTNPYFIRLQCETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDD3</accession>
    <name>A0AAV4NDD3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_370191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003270">
        <property type="protein sequence ID" value="GIX82837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043988556" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8729" checksum="190D148EB1FC96C6" modified="2024-11-27" version="1">MTIKVRLVQCVLPLVWCMVTPDRQTACTTSMHAVNKGVKQGLWKTLHSSTRAILTPEWFWGGWRIATALPRASKHVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDL0</accession>
    <name>A0AAV4NDL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_17368</name>
        <name evidence="3" type="ORF">CEXT_124521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003182">
        <property type="protein sequence ID" value="GIX81905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX81905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="719" mass="79306" checksum="3EA0CF82A8C1C889" modified="2024-11-27" version="1">MAAAATKDAKMAINGPIFFLVQEQAKSVVAIQALQTRMAVLETLQERLMQAIDDVHLHLASSKDSKSNTSSSKHSACCLSSKTPPNSVTSSEKKLRFVESSNTTLETETVIQKTELSKSDSLNKDSGIGGSESSLAPVETANFPDEEDELLQLLELIDQKSLVLLKQVEGCGVAEDNKLISGMEEASSAHLLDNLLFEKVDAQRQLSEVKAERDELRRRLAKLELATEAVTKQKLKVQQQLDATLIENKSLQDKIHKTSEICRKAESLSYLADIERATIKRKYLEYSEKSRLKVSNILKETNVLELQKQLLSYVMENDILRAKLQQDEPSKIAQWLKVESKLRKELKESCEENHRLQEVLQSKNLEIASLKDKIRAMEESEDESCVKNFGMGSTEDWREPGIQNMYNKRSNLTTASPFSPLGYGDFSKTQSLPAILLLGAQAKLKEQDSMRANYNHIYDTGSFTEIPLNHSFQSGPPDNHSSHQSAYTKDLVDLTSPNEPSYSSTSTLVHSSCSNQPVLHAGLSTPNLTGACNRDAVQNWVFAPRKSSAMVSSSTDIVSGAKLVNGHLCWKGTGKLSNSSCHLSRSEDISSICTEFDPLSDDNPSCENFVDSLNLSIPLKPTQVAMSQLSSIGDSLHSNSLDMGCATSPGLYQDTRKVHNARSVDGIRELLLENGYCKKISSSQYGHSSAAPIVLGKTGRHLPVNIMNCMHEASDYSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFH5</accession>
    <name>A0AAV4NFH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Stonustoxin subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_22816</name>
        <name evidence="1" type="ORF">CEXT_628922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020749">
        <property type="protein sequence ID" value="GIX82122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051077">
        <property type="entry name" value="Ca-dependent_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24024">
        <property type="entry name" value="PULMONARY SURFACTANT-ASSOCIATED PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24024:SF18">
        <property type="entry name" value="SHORT-CHAIN COLLAGEN C4-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="567" mass="62968" checksum="42F9392D5F96AA03" modified="2024-11-27" version="1">MGTAVMMYVLPMMLGQTYDLGKEKPGLQIYPKSVEQDAVTVQHYYTDSQYRMVENSAEIKDFLSISGKLSLKIKAGMVDVSGEGSYLKDSSSKTNGMEILVKVHFETVTKTIPTSLKPNADWALINENFLGTHYCRSIIYGGDLVASIRISATNTYDLMKIKAAVNGGINVGGGSFKGNIEGKLEMLKENAQDASSMEIKYYASVPLNGVSYDVDGLMKLIEEFPDHVRKVNNGTGNPLRMELYPVSSLKEGWPAYLENRAIGDELDDLEAQFDDLRETRRLLGVWSAALPPVAPSGVDEKIKTFTDKVNNIFGIYLKTIADLDVTKGASSQPIKDAFEAYEYGEYIMPKKYVRKLTELENEIYAEHPELAPRIGGAQYIRWGQSTCSTPETEATVVGVSSTSEIVQDGGSSQFLCSSLDPTVVEPKDYFNNYPGDDDPDYHLLVSPLRYVGELQRYKSMYMKQIACARCRAAIRTTVLMKVADKVCPSDKWTKEYEGYLMAPGQKSNKGEYICMDKDMTEPQGEVKFGNSDTNHLPEIQEVSIECGSLPCTPYVKDRPIPCVVCTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGF7</accession>
    <name>A0AAV4NGF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_731971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003329">
        <property type="protein sequence ID" value="GIX83400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9520" checksum="3B0320820BB13363" modified="2024-11-27" version="1">MKLVSTAKDHKFKGEHKGIKGRYRKSMSPSQVIPVGGQQLLTGGVRLTMCCYWADFPLFSYFIPGRLGVGSFNRVDISRAKTVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKV0</accession>
    <name>A0AAV4NKV0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_386831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003513">
        <property type="protein sequence ID" value="GIX85434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11797" checksum="6F2D7891AFA91019" modified="2024-11-27" version="1">MVEKREKFDGMELPARDEGSGKNGVLDVIIMCRQVTEVDYFLVATGIQFYSVLSPVPGDGDARNKSKNRTSFRGKIFHSIEGTKNTGQGLFGSQMGEKFDGCGTARKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQK7</accession>
    <name>A0AAV4NQK7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_751571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003563">
        <property type="protein sequence ID" value="GIX86060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9302" checksum="2CBF6E68EE28FA63" modified="2024-11-27" version="1">MCALTKAVVLLRRLDDGFRSSRVLINASRGNRKSWKISLTCVIKLDFVFERYLESLTNLPIPWAQWDITVGNRTFENDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NS66</accession>
    <name>A0AAV4NS66_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_388301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003700">
        <property type="protein sequence ID" value="GIX87616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NS66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="10319" checksum="CF42B64CBDB2E568" modified="2024-11-27" version="1">MMATPTQSQRSSVTYHVASDLANTKAPIRTYFIIISDIFPSFYLLSCCQRCVIPLDQLSSHLSATGTHVEKHIHVQIRRGIHNASTTFCLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSD3</accession>
    <name>A0AAV4NSD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_754581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021263">
        <property type="protein sequence ID" value="GIX87752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="11605" checksum="F94608257AA218F1" modified="2024-11-27" version="1">MPSSLNEGGPSSLLPPFIPFHGLASLGGGANTNLTTNKSIRTVWSSQSLKQIPQYKPLTHLSSVAGGTGISCTRILLPLWSGCNFGEPPSTPEGLGDHVHPNFCGRPAFPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSL6</accession>
    <name>A0AAV4NSL6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle and kinetochore-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_377901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003564">
        <property type="protein sequence ID" value="GIX86112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14651" checksum="37AA1F32D9223A4F" modified="2024-11-27" version="1">MAFLSSLRECVKKIESDVADVKHSYLCFESEETDKRSDFCLEMSRSIKKEITPLKHDYKQIHMSVNMDASKTYPKSSKRFGYEPFQLESCEEEYPVELSCNESKISEHELSLTPELNLPSLTEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P563</accession>
    <name>A0AAV4P563_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_26252_1</name>
        <name evidence="1" type="ORF">CEXT_780431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021663">
        <property type="protein sequence ID" value="GIX92169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P563"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13866" checksum="D5F9ED8C159F6D21" modified="2024-11-27" version="1">MNDVATQVVETGRIIMQKDAEKKIFPTKFKSFRNPLLKKKKKLNVFVQAKNELEELAIKVEAQREENDFLRSFLNSAVENKFEEFDLYRTFVTETREFFVNTLQEIKDTLKQKGRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAI9</accession>
    <name>A0AAV4PAI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_724161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004347">
        <property type="protein sequence ID" value="GIX94210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="10910" checksum="89B1042F83676672" modified="2024-11-27" version="1">MPHTNRFEEIPATTRQRQVEGSVHFSVVSLLALQGGCLFIPGSTSGSGKRHICSGKVTGCLPHQKKRPTFRIGRYAALSEAGDASTGVATISRKEESIVTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCL2</accession>
    <name>A0AAV4PCL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polycystin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pkd2_0</name>
        <name evidence="1" type="ORF">CEXT_424311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004292">
        <property type="protein sequence ID" value="GIX93738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11179" checksum="E1B13051A9B46391" modified="2024-11-27" version="1">MEVDSTSTPSALLRHFWVPCRFCLLPDNNDRPAEHLRHSHSQLFQDVKEDIGKQANDYEIVDFMWKKLKGFFFIFDDDKPKNDDDFDNDVKPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PG66</accession>
    <name>A0AAV4PG66_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_503681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004464">
        <property type="protein sequence ID" value="GIX95043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PG66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000107">
        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="87"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX95043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25021" checksum="65E6EDFF804EA715" modified="2024-11-27" version="1">MDCRASSYLYNDIYWRWTPYYSNESDLIIPDELLTKSIANNSITVKFKLDNIYLNHTGSYKCVAFPRQNSTPEEQSLFIRVREIQEPHFITYNWKVELTTEANSVLELDCSVDGTPWPKVTWYRNGELLVSNLTGFRFENNFQILIISRLVEEDSGDYKCRAENVAGVIMRNATLSVSSSGVPVSVVQTNPQSMQNWIIAGFILLFGSHSAGHICQMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHH6</accession>
    <name>A0AAV4PHH6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_280851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004516">
        <property type="protein sequence ID" value="GIX95435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX95435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="22849" checksum="213A5F22C0252338" modified="2024-11-27" version="1">MQQNGGKTPPGPVGLPFLGYLPFLEPNPHLVLQRLAKDYGPIFSFEVMKQERTWIFKNILHELIYTIPQQKNDDLQLKDVQEKTHKEARLNRLLTRLSDTNLLHGAFSSKERRYLLCCTEATIAQLLRRSNSIPLMFLGVSVTLTLSNCITEPAKTIGMLAMANGSKWQMIKDLIRHTLYVILKETRKIPTFTLSYNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PN02</accession>
    <name>A0AAV4PN02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_311121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004962">
        <property type="protein sequence ID" value="GIX98782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PN02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14373" checksum="350B5EFE0EAC6F8A" modified="2024-11-27" version="1">MNYKKLRILRLHFPPRSYFEDCPEELLDKVLPSLENLKIFTICNSEIDSFGIHSLISTTLTHCPKLTSVGHFDSVMATDFIKAKSDKSHTGCLRLKKCFWRLWNAVNLYIDEMKCLTCNPVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNU6</accession>
    <name>A0AAV4PNU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_483971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004709">
        <property type="protein sequence ID" value="GIX96897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7724" checksum="ABAF2F01708CB8F8" modified="2024-11-27" version="1">MLVIIPPSNAPDWWRVGRARIRILQSLQISLMFTFHEPWSSDRGRHKWTVASSTLDYMETAVPLSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PP89</accession>
    <name>A0AAV4PP89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General transcription factor 3C polypeptide 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GTF3C1</name>
        <name evidence="8" type="ORF">CEXT_771271</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004964">
        <property type="protein sequence ID" value="GIX98818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PP89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042791">
        <property type="term" value="P:5S class rRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044210">
        <property type="entry name" value="Tfc3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007309">
        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="B-block binding subunit of TFIIIC" evidence="7">
        <location>
            <begin position="178"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX98818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="485" mass="56173" checksum="1B98928EB6473F73" modified="2024-11-27" version="1">MRFKKDYDFLSSILDEIALEGLDGITLEMFWQRLRDRPKFPIAVDDDSKNYFWDIVAKHKDIEIYELPEPREFAPVYNRYSNVDSEFGVVVDSEVPIPDPYAPIVTVRDNDVRGSCSTYETRHCITSEIRNGSVLLVTLEQAMEKWGNCLALVASPKLRLTTLIGMETDPLIDISLNAYCLLERIGRSRYLGEVTQGEEGLLALRAGFCKQLHYHRNKLTLKGLITKQNHYVKNKKGATVTGSLFHLTRFHVQRKTEMVIWLQRLCDILKDKPQNRESCKVIKDEMGIPEFSFKKLSSRPFLKWIRIDKIPCREFYPNANPKGWFYGNGENKYERVCQLLRHCDDDTDESEEEADEKEFSPNVHFDASKIYYGIPLVHQIYFHIKEAGPNGASSKDLGRKMTLPRLDIRSLLNILLKKGHVISVLEDRGRQKVKRYIAEIYADQNADYSLLKKQDAICDFPTHTAKRKRSDEDDTPAAKSYNRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUN4</accession>
    <name>A0AAV4PUN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_587751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005227">
        <property type="protein sequence ID" value="GIY00810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11413" checksum="6DB7D28330675034" modified="2024-11-27" version="1">MLQRKTKHAALLYKVATGSFSPNLSVIGQLILLSANNAPFRNVLPLSHFVANCARAPMQEACAEGRLWTDPDMGMTFCKSQCNNISEAGDSLLCWSKSKSTGFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV86</accession>
    <name>A0AAV4PV86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_815311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005105">
        <property type="protein sequence ID" value="GIX99845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9063" checksum="C4B80D9738D9BAFA" modified="2024-11-27" version="1">MTNQVYKRSSPTSETNLAGKQRCRSNCSIQRLCHNSLSIGFRDTFILDRQIPGRCLNVLKSNEYAMEIPTNSLSIQMPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q373</accession>
    <name>A0AAV4Q373_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_802511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005507">
        <property type="protein sequence ID" value="GIY02832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q373"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8087" checksum="EFAB507853CA367B" modified="2024-11-27" version="1">MQKACQLGDGSTFNRRLAVDFGKGKLMECDLAMAFNDPGSMNQRIKTRGQNAGSKPGILSGGYFEYPNLQNGRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAH1</accession>
    <name>A0AAV4QAH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_731931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006041">
        <property type="protein sequence ID" value="GIY07043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="13954" checksum="A94B1E815FED00B9" modified="2024-11-27" version="1">MHANRSLLPSNSTSSLESEKDIIYANKCRFPLTIESACGTTSPSRRIKNVSSKWRSNKKVSSGTTSPSQCCSNQKVSSGTTSHSQWCSNQKALVSPQYLECSNPPSLCSQTHGRIFLQFQCTNTSGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QE54</accession>
    <name>A0AAV4QE54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_462841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006100">
        <property type="protein sequence ID" value="GIY07405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QE54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="19" mass="2296" checksum="81D866767B91D314" modified="2024-11-27" version="1" fragment="single">HFAFAKFNITFLNLEILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QES0</accession>
    <name>A0AAV4QES0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_9430_1</name>
        <name evidence="3" type="ORF">CEXT_103761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005973">
        <property type="protein sequence ID" value="GIY06530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QES0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14693">
        <property type="entry name" value="bZIP_CEBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031106">
        <property type="entry name" value="C/EBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334:SF20">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334">
        <property type="entry name" value="CCAAT/ENHANCER BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="212"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY06530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="303" mass="33353" checksum="5F40ABE6E9BD4AE4" modified="2024-11-27" version="1">MYDPAFPSVDDLKAKLNKAPAGLQQHKGLLEQLGDNSVPDLSDLNSPELSFDLQNIIGPDGGHPAGGLDESSSLFSDILEPQKQPQRYPSVLQQHGQLGHPFARYQHMPQQSALGTDQYGSEAGLGIKREPLDHIDLSSCGQRSFAQGANIYSYPPITDRQAASVLGSYLPNLGRPAPPASSGSLKSLSSSSSSSGGKHGSGKHKKTVDKNSDEYRRRRERNNIAVRKSREKAKIRSRETERKVSELVRENDYLRKRVEMLTKELSVLKNLLSNVGVPPDSVDNEVAKQMHHPMDPYHAMQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QF06</accession>
    <name>A0AAV4QF06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_535921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006274">
        <property type="protein sequence ID" value="GIY08648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QF06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13067" checksum="16B420264544DD01" modified="2024-11-27" version="1">MPAIMMEAAENSLLNPQMTPVKCSPKHIYSPEPLRKKASGIYINYTLSDLRHGKGVQHRAARRKDMAGKTKCTIKGSVLMRLQGSNSLDHKVKMECLEKEEHSFSSNISGVGEGNVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QKJ8</accession>
    <name>A0AAV4QKJ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rho GDP-dissociation inhibitor 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Rho-GDI gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARHGDIB</name>
        <name evidence="7" type="ORF">CEXT_586111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006542">
        <property type="protein sequence ID" value="GIY10583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QKJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005094">
        <property type="term" value="F:Rho GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.50.30:FF:000001">
        <property type="entry name" value="Rho GDP-dissociation inhibitor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00492">
        <property type="entry name" value="RHOGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00053735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00080671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY10583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="25110" checksum="9967643ED96E1E33" modified="2024-11-27" version="1">MWSKYFLIWIHYPETIAKMSDGDKAPEIHDEEDVNYRPPPEKSLKEIVEADQNDASLQKYKEALLGQALKEAVIVEPDNPNRVLVKRLALVVEGRPDVVLDLTGDLQELKKKTFVVKEGIQYRIRIDFYVQREIVTGLKYIQKVLRHGIQHEKLTHMVGSYAPKLDMQSYSTPVDEMPSGMLTRGTYTVKSLFTDDDKNEHLKWEWCFELKKDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QM73</accession>
    <name>A0AAV4QM73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_593081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006363">
        <property type="protein sequence ID" value="GIY09332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QM73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15591" checksum="CEF2936A7F1E3FB4" modified="2024-11-27" version="1">MSSIPHNLKSISSRPAPSPSSANRETDGGYGLQTKTFSTQCMLAGMSLKCPPHFTCLIRTPTSFNQNSSRGTSKSNFNGEPDGRVASALYHRNNRSVQPASMNTPFMNNDLNRKSTHIIESYITGGWDGVSVDRPPICGVHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMJ4</accession>
    <name>A0AAV4QMJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_692711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006371">
        <property type="protein sequence ID" value="GIY09387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10848" checksum="253FEDDF2BBEED02" modified="2024-11-27" version="1">MNKIDDEISSNLYFITLSEQRIESTRNEVFYCSICGSKTEEQGIKSPTFRFCFLESYPKSFEEHCHPTTVTFRDPCLRESKKEKLQFSSMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXE9</accession>
    <name>A0AAV4QXE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_130071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006779">
        <property type="protein sequence ID" value="GIY12378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11624" checksum="301A518A1EC0E94E" modified="2024-11-27" version="1">MLLPRETQTPCHRSHHYLTQLLVTESRGENYFLCSSKPWHSVQALTGQIRSPSDLKKSLSKPKALFFRTFERLPGTSGDFCNCLEVCISLYTLGSLCCIEISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZK5</accession>
    <name>A0AAV4QZK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_171561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006954">
        <property type="protein sequence ID" value="GIY13535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12765" checksum="FC3AB0139AF90E90" modified="2024-11-27" version="1">MECLPAFHKYPFADFLCVWGEKDGMDQLVIVAHITPVSAFVNLYRNEPINLIRFVVVNHFGHRWKCDDDTEDYNRLVDHSFRHIKKHKNLDYQQQKGHLQWPKRNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZL4</accession>
    <name>A0AAV4QZL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_614351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007138">
        <property type="protein sequence ID" value="GIY14734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14296" checksum="636C61C3BFF59BFE" modified="2024-11-27" version="1">MCFWCCYHGTPFSPTSLYEAHGVLSFAIHHVRRGDENPLNIPPHTGSSYFIDFEFYSQGNELLGEEGSFKIPKMNKSFWIEVFFCSSVSHRKTIYESRKLILNSFNGGLHIHLMKQFLRNGLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R057</accession>
    <name>A0AAV4R057_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_605401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006999">
        <property type="protein sequence ID" value="GIY13757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R057"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11171" checksum="D57421F16569182F" modified="2024-11-27" version="1">MRYGDQLKYVTQKARCNSVTLSYNCPTAPPPPPMTSVKTTTPLPPPPSTEPVPSTTIATTMNSVSKPRTIIYTLPPTPGSRVSAANNGQGTLLVTLLCIVSSVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5S9</accession>
    <name>A0AAV4R5S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-directed RNA polymerase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Polrmt</name>
        <name evidence="4" type="ORF">CEXT_412092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007252">
        <property type="protein sequence ID" value="GIY15605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="228"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="3">
        <location>
            <begin position="373"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY15605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="826" mass="96186" checksum="1C93F95D1BA88EA3" modified="2024-11-27" version="1">MKSLYDSKATINFCYFKSWKCCRCSYKFCGNVEKKAQFSTALKTKIALEPEISKKKNKVEFKKEYKELFKLLKARECSLVNKTVLDRTKVCKNASDRTKNFKISENFTDLCNKENISQSELLEKPKNHEITEGIYTVKFTKPKKKKASSKKDSPDSNEENAKKLKRKKKKLSLKQENIKQVTKYSYDVHALKSYVEISINANEVEKTQIYLRKKMMSLKKKYKIETLGVDLYNLLISGWAKKGRLDKIKEVFSFMEEDQVSPNLQSYVGYLEGISNCKLKDINQMQQVIMDMKKKKNLCPEDILKKCVFKGDQREKVIEVLGFVGVDVFSDPIEIGDAYSCRLLQKLNAKSFGRGESFPNFGFQEKDIDSISSSQLEMESRFQLRIKSVDARTYLEKCENVWREEFTKSINKFKIEEKGSHAQNFYREDSIYPYISVIDTNILVNLMLQQVKALAEMGEFYNPSEKFIFKELGIKVMNHYFIWLNKTNKITDKYFLDKKLLAKYTPREYWEYLKQQNSKGPTIDITFTPWPHGVQVKIGSKLYSIMLQKVTFDENQVKKKIQQKFLTPGFYLHCESGFIDGEFRLSRNIGTHSLLCKLYRDAKLDYLEFDATLIPMLSPPKPWVKYDSGGFLITSTPFIRFNENAMHLNDFYSQVPPKNLNPCFDSLNSLSICPWTINKPVLDLIIDVFRKGGDEILDVPLNPNTLPPAPKVLSSMTQQERIIARGKKQEIRKKKCEASSLWYDCLYKLSIANHFRDEVFWFPHNLDFRGRTYPTPPHFNHLGSDLIRSILLFAEGQPLGKNGLDWLKIQLINLTGLKKEILILYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDQ0</accession>
    <name>A0AAV4RDQ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_137861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007646">
        <property type="protein sequence ID" value="GIY18572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDQ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9349" checksum="26AB2AD025AE0371" modified="2024-11-27" version="1">MKHGWAHLSEPAFIDSENQRAPQAVLDVIKKASLKTNKKIIMKQDGFKDTKISHFSVTLTTQMIHSILRTPDKPTMGNAASFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RH92</accession>
    <name>A0AAV4RH92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_184084_1</name>
        <name evidence="2" type="ORF">CEXT_18581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007835">
        <property type="protein sequence ID" value="GIY20076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RH92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="723" mass="80662" checksum="0F8BC45659CB3C9B" modified="2024-11-27" version="1">MLRHILGHWKAHKRKPSLLPEDIESHSDDPSKVNPLFEDSEGSIASSPRHDGDRNSTTGIDLDLVDVSIPKETNEEKSDALEETPDDVINRIDIALDSSFINDKDSSEEQLKSSPEVARKETETFSNPDKKAMVQEKSESSENQPRMSRLHQIMKTHPELKKELVSDITIFKSIPNKTSESKSNQQISGKENQLEVSTDASAKSEQSSEQTAIPSTSTGITDGSSKHSNTSPVTSIPNNSPVLNMSSSSTPATNRDLNSSSISNESSSSTKTSSTTTASNKDSNITPVSDSNAPFVSVKEPVSETKPKSFKKRAIDELIKKFQGSNSENVQKVSSFLHSNNKKETLDDSKSKDKTESESAAIKKEQDKESLSKIFSFPPPPPAEPKKNNSKKEKDVLPKATKVAATSESVSKIDSNFILTEAKTRTDSSLSRKDYNNRTVATNDVPNVLTSKQKEEKGKQTETKKERLIAFQQNQWPESITTSTEAKSTIEKLQKPNDIQTKSSRSTVSQLKTSASKTESDITTPKKDPDATKSHSEDSGITRGDQISSEVSPDVPKEETKNENDVTASTPTKRNTRERRTMHNRNRGCKRCKRFSYDGEAPLKRSQCDDYYDVLTGLYRAHKSKYSDSWTSDLSHEERDLIRRLRSRRDTLRSNGLSGKSRHPRHTRNPENGHFHRHHPVRRSLSDESTFNSSMCSCDDCWLFLVKDYAYGRASLRGMARKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLZ9</accession>
    <name>A0AAV4RLZ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bro-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_514971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008139">
        <property type="protein sequence ID" value="GIY22387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003497">
        <property type="entry name" value="BRO_N_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02498">
        <property type="entry name" value="Bro-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01040">
        <property type="entry name" value="Bro-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51750">
        <property type="entry name" value="BRO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bro-N" evidence="2">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY22387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="256" mass="28960" checksum="D9B588643266E324" modified="2024-11-27" version="1">MSIQNKVVSFAGVDIEVASIVHDDQVWLLANPFARILGFQRLNDAIQYAVTSSNLKSLAELGGRVAAPSRGNPIQKRSKFINRAGLFELIDKSRMPRAIEFKHWVNNDLLPNSMRLVNIAWSRTRLQLRPPRSMPSTKLQASTANRPLGTKKGLNSWSESTLRTNGSSGPERDLVRHILLVMKKPDVDEYCFVRRQRRDIARGRQQAVDKGFTEQLAEFKDIPNGVNVMNRLKERIPPAHHTTPNLTQCYATILNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RN14</accession>
    <name>A0AAV4RN14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_409661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008155">
        <property type="protein sequence ID" value="GIY22484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RN14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19985" checksum="678DD24B6F46E398" modified="2024-11-27" version="1">MYGRQWGHSGRTKITEDRRWCNGKPYHSSQIVFEIIIQSSSSAKTTEKTKDNLQTTSEDVIQEPIKEFQVSTCEDENKDSKYIESTREELEELFTTNDEDLLDIQKSENKNRMSYNCQFCAEIAIDFRRFLLCSIFRKSVAKVSPSEDKIQEWTDESVWFAPSEPTTNNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNE1</accession>
    <name>A0AAV4RNE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ionotropic receptor 93a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Ir93a</name>
        <name evidence="1" type="ORF">CEXT_746631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008248">
        <property type="protein sequence ID" value="GIY23224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="34706" checksum="F3B3118C56BAFD2F" modified="2024-11-27" version="1">MSFTAPIVEPFVAQAGTEDARANILELEGTLQDTLGENDQLLFTKNIKYTNLGDLLMSYSEKERGCPRPPPKIGFGVPYLNNMLDIVPFMVDIRSDNRVLDKWDDIIILHDNTIDLNSLEALVSMLHTMGIRKRSTTLTIYNVCQAGSCEDMSVTIQESLTPYSVIDFPKNFLILSTGKAFRKIIEQAKKLRMLDGERQWLFVATKHLLDSEATIAANSLPPEANVALVYPDNPVNQKKIAWTTSGTKATCGGCLNLVMKTTAYLQQGKKVAQTIDDYETVGTWKLFGGFTVGWSLCIQGRQEISEGGNLTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RSY5</accession>
    <name>A0AAV4RSY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_435021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008271">
        <property type="protein sequence ID" value="GIY23405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RSY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY23405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11911" checksum="9843EE409E493093" modified="2024-11-27" version="1">MVITGEESSELQIRSTEDGNSAAEGGRKKEKSKSSPHFVFSPLIFAFPVSCLHIMLAGVRGNDIMQTDIRPVLMDSVNRIEKFKRQARLLDLMGWNGEERCVRVCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXW5</accession>
    <name>A0AAV4RXW5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anticodon-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_470591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008703">
        <property type="protein sequence ID" value="GIY26595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9460" checksum="A309E6500C8A6E72" modified="2024-11-27" version="1">MEKLTNCDIEWRSQPLALTSDLRESHKPAVRRGYASRVKAVIVGEEYIEERSQTETSSGPLSNIYDEIRKTGRISNTSFEGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6M2</accession>
    <name>A0AAV4S6M2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_566551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008900">
        <property type="protein sequence ID" value="GIY28062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6M2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19316" checksum="C5C2BBF00A307BF4" modified="2024-11-27" version="1">MNSLKTRIRKRKKMNLKFQRNLEAKSTLTSENENQGLENQPSTSTENDQYYQNINTKYTCSSHQGINLFEGGNSKRFEDLNKAALLPQRKTVPSSTIASRPEISIYEHPVEITDSNNLSDCSTCSMDSLKTTILKRNGKDLKFQRNLEAKSTLTSENEDQDLENQSSTSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE00</accession>
    <name>A0AAV4SE00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_716821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009474">
        <property type="protein sequence ID" value="GIY32209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="31" mass="3763" checksum="6128B3E97AEB8557" modified="2024-11-27" version="1" fragment="single">AQKMFNKSDEQNWRRRRKGESSQLSSLPRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SEQ5</accession>
    <name>A0AAV4SEQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_249281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009527">
        <property type="protein sequence ID" value="GIY32640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SEQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="14971" checksum="96E2AA66B6FB1A08" modified="2024-11-27" version="1">MAVRIDFSRFKARNSPLTLLLEGVSAVPNSPQCYLLLLKKSFGMLGRSGVCSLERKSNAILSSEASTVDNGGLCSKTFLWRLGDLTKCPKKTTATSSSGGGICGVCFILLFATILQSAWIVWREKGWLPPLHHPKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SEU0</accession>
    <name>A0AAV4SEU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_262441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009304">
        <property type="protein sequence ID" value="GIY30995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SEU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12300" checksum="79F883093F40E2D7" modified="2024-11-27" version="1">MSTILHEFRSTDKCFSLLKYIKIRTFSETAQDASRTFLTKGLSGSERMMELRRDKFKGKNDSGFRNFPYRNSLASGNVDGNFQQVEMYYTYLKGISKLDCIYYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGK2</accession>
    <name>A0AAV4SGK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_342471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009403">
        <property type="protein sequence ID" value="GIY31640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12784" checksum="D55E4BBF7962A237" modified="2024-11-27" version="1">MIFLESNWFETKLFFPPYRTYKEQKNLLKCFPWSEIYQLPFHSSKGKLSPTEPHTLVFENLTSYILMLLKSELEHAYRKKKIEKNISKSFAIQNFTKTSPSSKEKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIS9</accession>
    <name>A0AAV4SIS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_252411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009511">
        <property type="protein sequence ID" value="GIY32442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10100" checksum="EEF1BF871CC03392" modified="2024-11-27" version="1">MPIRVIDTFWWRLIDCCCSLSKTAGPTTEGTWQMRRLPMATGVPRFLIPPLLTIRQYERLLEDVLMKYRLQFPFVWTILFLFTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJM7</accession>
    <name>A0AAV4SJM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_616041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009712">
        <property type="protein sequence ID" value="GIY34000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11265" checksum="480385B2A6EAEC98" modified="2024-11-27" version="1">MGTVPSAKERGKSITPLSFLKPNCSLGSCVQKCRGAYLRVTPGARPLKSINRPAPSVIDAPRYHEKGHLSITTDKRSDSICSCNSFQLYFKSNGRTKTIFSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKR6</accession>
    <name>A0AAV4SKR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Solute carrier family 22 member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SLC22A6</name>
        <name evidence="2" type="ORF">CEXT_660571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009691">
        <property type="protein sequence ID" value="GIY33796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15140" checksum="CE534B27F3733C96" modified="2024-11-27" version="1">MDMFEVIGSFGPWQRRVFILFFIINIVGMWQNLAITFFAPNMDFRCVEPSYEEEPGANETAFDNRCEVPANGSNASVPCTKWEYDTSFYSQTIVSEWDLVCGREWFISLNKSVYMLGFLISVFFFGQLSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T6B6</accession>
    <name>A0AAV4T6B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_33271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010653">
        <property type="protein sequence ID" value="GIY40734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T6B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10514" checksum="4274A52243AA67F5" modified="2024-11-27" version="1">MKRKRPIPKSLVARRIGSHDLCLCAEVRSNGFELRRSRHPRPPIAQQAAKAWRISLAQLLLRLPLIRWAKKKVGRWIDVIELAVALFAADAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9Y1</accession>
    <name>A0AAV4T9Y1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclin-dependent kinase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cdk4</name>
        <name evidence="8" type="ORF">CEXT_611151</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010808">
        <property type="protein sequence ID" value="GIY42146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9Y1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF472">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY42146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="247" mass="28270" checksum="83C71DDCC9102A92" modified="2024-11-27" version="1">MTERKRRKPSSECAAGFFGKTACVVCNPPPLLVSSPPEIFTDTQQHRFLHCNRIVHRDLKPQNILITKYWTCKVADFGLARIFENQVPVTSVVVTLWYRSPEVLLQSSYATAVDLWSSGCIFAELYRRKPLFAGQSEVDQLRKIFEIMGSPEESQWPEVSMPWVSFKNFRKQPLDTVIPEITAEGLDLYRKLLIFDPLQRISAKDAMNHSYFKDFELQKPLYKAKKRKSARISLGAEPGTSAIAPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBL0</accession>
    <name>A0AAV4TBL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_150201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010926">
        <property type="protein sequence ID" value="GIY43079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19548" checksum="7B65A63A287B83D8" modified="2024-11-27" version="1">MLRCIQTETHTGLRSNHAFKYQLLIFLLAYPGTFPQQGPYLRTGPGWITLAPGSETAELIKHARRLPDVEGTLLLHLTVVGLDLSNAEESLAKIELLKSIPERMNFSAPGWFALRDNSCTTAFDLLFSCTSTLMVLFDFITCTPFPSSEGYRWTLCCWSPLVQIGIRNSFKKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNU9</accession>
    <name>A0AAV4TNU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_334941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011576">
        <property type="protein sequence ID" value="GIY47414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7809" checksum="2B65BCDB156513AD" modified="2024-11-27" version="1">MCSSPHDAIQIQIQSSMDEIYQWILHKRQCSRFVNCVVPPAATQDIVFGTQWAGSRCNDNVTQDAILGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWR1</accession>
    <name>A0AAV4TWR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_339571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011847">
        <property type="protein sequence ID" value="GIY49516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9112" checksum="7F6C67046C5B1794" modified="2024-11-27" version="1">MYSIGKKCSLDIVFKGSNSTSQLGLDVDFRDGNVEWVLKYVSDSYTVDPTSWKRSKPKHNSNREFVRSLLAKSLELAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWR2</accession>
    <name>A0AAV4TWR2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EGW08_023739</name>
        <name evidence="2" type="ORF">CEXT_27991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011828">
        <property type="protein sequence ID" value="GIY49400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052560">
        <property type="entry name" value="RdDP_mobile_element"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688">
        <property type="entry name" value="ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="253" mass="29347" checksum="038DD1FA170FE142" modified="2024-11-27" version="1">MNPQSNVFAIDDEHARTNIEAENMLQSNMSKQKKPHKKTVAVFLDLFAAFDRVWGQKLILIIHSTGIKGNALLWINDFLRGRKFSVRFNGARSKTHNGHGYLRAQFLVLVSCFIFYTNTIHPHIHSDTRIACYADDIAIWHTHRDITTSQKALNVTLKNITIWAKHLKLSINAVKKHYCVFSTDRKRRSTFNLDIKINDSPIKRIEFPTYLGITMDPELRFTIHIEHTANKALRKLSIPKIYVELLEEQDLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYI1</accession>
    <name>A0AAV4TYI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_804341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011927">
        <property type="protein sequence ID" value="GIY50022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15062" checksum="3B0FC5267961F2F3" modified="2024-11-27" version="1">MESRVKISQLIVSDDQNVEVRNAEENINLEAVPETEENIVDSTPELENISGGQQQNAQGAEGINVPPMHQPHGNSFQTVRGNFSHLIKPRSNKEGVENILRNLFEMENSDSQNNSQSKRHGSDYVWLNNEILPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3E1</accession>
    <name>A0AAV4U3E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_184811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012209">
        <property type="protein sequence ID" value="GIY52197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="7680" checksum="048EB3FA9848C709" modified="2024-11-27" version="1">MVSTLDSESSDPSSNLGGTYFLLALQLPCGLVVRIPGFHPGGPGSIPGMGRWFHGVMVSTLDSESSDPSSNLGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6Z6</accession>
    <name>A0AAV4U6Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_222941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012376">
        <property type="protein sequence ID" value="GIY53584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19408" checksum="41F8DFF671A7E2BA" modified="2024-11-27" version="1">MKHGLLWVKLILQCNKNNLPGIHQQTGYEENAADEMFSWYEVTKQNPYNPETSDFPFPGMHPIQENESNSMHLQLPYEVSKVSFHQNSQNYEPLNLEHPTNIPVSLTERSILTDSQQTFGQRNTPMHQMSQNPNAFSQLECSGMCSTNELPPILLPPTIISVKGTIYCLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9D0</accession>
    <name>A0AAV4U9D0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_615591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012485">
        <property type="protein sequence ID" value="GIY54225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9D0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF159">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 74D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY54225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="218" mass="24745" checksum="E59089E2BD57ABE6" modified="2024-11-27" version="1">MEKKKRKPPFKPGQGKSVLLQTATGALSQKHFEEAPEDKDGSCGIWSYKPEWLQMLANKKVFLAVFCLTSVLQGMYYTYFVSVLTTIEKLYQIQSKTTGLIMSATGDRSNWRCSLLTYYGGQGHRPKWIACGMLVFGLAALFCAAPHFLYSDLTKSYTIYLRQREFVYTCAEGTQIYTLPYTTSPASGTQLLSLPLFHPIRHRKILCRLLTVPRTKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAC5</accession>
    <name>A0AAV4UAC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_310671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012550">
        <property type="protein sequence ID" value="GIY54743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12350" checksum="D1DA4E1B7A511FBB" modified="2024-11-27" version="1">MLPCTVKKRWLANLISRFTCKASFPLSNLEYLMHKNDSISLEQSEESRHAAPDHGMNIPNFIFTDWNKGLSPTNRQTDTRHRRFAYVLAKASHLDAFELTEVTQSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UGN2</accession>
    <name>A0AAV4UGN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_778351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012826">
        <property type="protein sequence ID" value="GIY56919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UGN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="9021" checksum="53775086AC78A320" modified="2024-11-27" version="1">MSAVENVILHIIEDSPSFYKHENDDVWRRIILRKKKVLNDLENAKAVKPGICSSNLMPFYRHLMYRRGIRRLDLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UII3</accession>
    <name>A0AAV4UII3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_487871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012938">
        <property type="protein sequence ID" value="GIY57656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UII3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10761" checksum="719E6F3E08E366CE" modified="2024-11-27" version="1">MTFSDVEPAMPHPTVRHAVRDHLGERGSSDDRLTITSPDPPSALEGHITNEAAAAAPQYCRQVATMALFFNRHGYRSVLATKCLLEITVLTTVFLLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UM76</accession>
    <name>A0AAV4UM76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_410261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013125">
        <property type="protein sequence ID" value="GIY58903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UM76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="39" mass="4393" checksum="FDEC76D67AE79231" modified="2024-11-27" version="1" fragment="single">MLLVISARNKTNFTKSDDIRSSEAIVSFKTFMAGDEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URW3</accession>
    <name>A0AAV4URW3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_348271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013335">
        <property type="protein sequence ID" value="GIY60522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13889" checksum="28815E26269F514A" modified="2024-11-27" version="1">MCFLPTSVRPTTNVTDPTDSLPRASAFKCASRITLNVLVEFEEANQPKLQNIAFGFCSWNGRWLSLYDLCFLISLGIPLILIRSNNILGLLTASISFWDAANFYLFSRNSTQFERSTPKTKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWF9</accession>
    <name>A0AAV4UWF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_95441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013502">
        <property type="protein sequence ID" value="GIY61695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9807" checksum="2E4852072D2AF6F1" modified="2024-11-27" version="1">MDWLMGMDDMNAFRHTGKVSQNRTVYFEMILHCKFVKSSVADVCGFRALFHVGTSYGFFPLRSKVSSPTRHSVNDTLASSISSRLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZ74</accession>
    <name>A0AAV4UZ74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfotransferase 1 family member D1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Sult1d1</name>
        <name evidence="4" type="ORF">CEXT_205501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013704">
        <property type="protein sequence ID" value="GIY63132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZ74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="54"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY63132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="268" mass="31884" checksum="25FD7736E11E3776" modified="2024-11-27" version="1">MANVMKRPRYAKMNGLLYPAMFSPKCFQEALEYKPKPGDVFIDTYPKCDLLGMEGIINMPRPGAFKTHLPYSYVPHSPDAKYIFVARNPKDCCVSFFYHTRDQPGFGYWDGKFDDFFELFMAGELEYNDYFDHLQDWYPHRNDPNVFYTTYEDMKKDIKSVILKLSRFLGDEYIEAIEKDNVVLNNIILYSGFDYMKKMMSEMRNLRESEDMDFTFTGLNHMYEFNKSLKPPRDLPEFAEVRKGIVGDWRNHFSVDQTERLNRKFLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6U9</accession>
    <name>A0AAV4V6U9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_807811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014014">
        <property type="protein sequence ID" value="GIY65654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6U9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY65654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12739" checksum="07CE03A1821B0772" modified="2024-11-27" version="1">MLFCRTFLSPATLTSGQMTKSISKLPLRQIPNPGDPPLQTIPLENRSNPPEAKRKPRAHETAFYTDRDRTAYAIIAFFFFFFCACIIYGCRTASLYPAAVVRRGSYTKEGVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUD3</accession>
    <name>A0AAV4VUD3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_792531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015155">
        <property type="protein sequence ID" value="GIY74032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUD3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9303" checksum="34AD593A889CC823" modified="2024-11-27" version="1">MSMPRSGVSDAAASFFDFNRQAPAVHKQITKPPKELTNIKATRHSKAVSRDLPNKTMSIPRAVMHVQKRATDMRKEGTEKNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVL0</accession>
    <name>A0AAV4VVL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_301941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015223">
        <property type="protein sequence ID" value="GIY74496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14368" checksum="FE0C6D21D224B6D3" modified="2024-11-27" version="1">MGIAGRDIGIELMEYGHRVMKYGIGVMEYGYQVMKYGSIAGKRVYMVSGDGMWASPAGEHGYPRKDYMGISIYMPNPTPTGYIAMGVMAYGITGRIHRYALSDGIWVSPARNLGYQVVKYGYGRKNMAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7G2</accession>
    <name>A0AAV4W7G2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_444621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015678">
        <property type="protein sequence ID" value="GIY77779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7G2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11050" checksum="14BD8B1373F0E3E9" modified="2024-11-27" version="1">MPLQPSPPRPRLGEGRGGAHLPFVSKVTHGFFVARQCHENQSYVNDIGSALPQSRSTLFLIYLRNNCGNRLYALPTHIKPLRTMSNATLRGKNVSSPLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WB25</accession>
    <name>A0AAV4WB25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Tf2-9_48</name>
        <name evidence="3" type="ORF">CEXT_388551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015844">
        <property type="protein sequence ID" value="GIY79079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WB25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="2">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY79079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20822" checksum="7C2CBE7831ABD885" modified="2024-11-27" version="1">MNPSHAHLTGITTEFRFISIQRLPFGLKNAGASFQKTYEHFPYGVNLPDFDKPFAICTDASKYSLGAVLVQEDESGVSTPQFPLLLENLDPRKNILWWKGGSGSGFGINHFKNYLYGSHFFVYCDQQCLSKLMKLKDQRRVLPDGYLPYSNIHTQSSIKPGRLNLMADYLSRAKYSIIMKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBQ2</accession>
    <name>A0AAV4WBQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_55693_1</name>
        <name evidence="7" type="ORF">CEXT_653231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015924">
        <property type="protein sequence ID" value="GIY79733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026052">
        <property type="entry name" value="DNA-bd_prot-inh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11723">
        <property type="entry name" value="DNA-BINDING PROTEIN INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11723:SF17">
        <property type="entry name" value="PROTEIN EXTRA-MACROCHAETAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="76"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY79733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="21583" checksum="70B63AA5B43B3ED3" modified="2024-11-27" version="1">MTEYSSSAHHFHDSIYTRAFTVFRTLRLLPSSLDTRISSVRLQSFFVSDYFSDSVLIIMKAQQCDLQMAAKQMEQKLKSRVSKDRDVSQEEMQSLLCKLKTLVPYMPRHKKLSKLEIIQYVIDYIMDLQIALETHPAVPKPTATTTTPIDSTAKIASKKTPLGLNTQGINASCELKPYEIAVLDVIAPNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCR0</accession>
    <name>A0AAV4WCR0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_540271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015925">
        <property type="protein sequence ID" value="GIY79741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11653" checksum="581D0A36C5223A10" modified="2024-11-27" version="1">MFVASFLAVFGQRSFRIPLTMQDMVRFHGRGLYLESGCRSPQLCPFVQHQFFVLHHGARKDASHQRNFKDLSKEVLENRYRCFAPNWIDRSAFTAREQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WCX6</accession>
    <name>A0AAV4WCX6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_784891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016004">
        <property type="protein sequence ID" value="GIY80366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WCX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="8134" checksum="26ECE11F050F65C4" modified="2024-11-27" version="1">MMPIIISGFLKSNSGCSMPNPRLAYLVDANIWAFGLRRHVAVVEFCKRWALLCHINAPTTPSKSSRRVSCSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHX8</accession>
    <name>A0AAV4WHX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_239711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016118">
        <property type="protein sequence ID" value="GIY81409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13956" checksum="403D437F58359843" modified="2024-11-27" version="1">MLGDILRTEGRSNIRLQTVKGRIKEPYADTGPEVEWQPTEPPPLGALPSETLLPATLPEISCLKLKTAMQKLRYESQVLNGTGLVQRKDPEENEIFLRKMSLSFKNLPHPPTHVGHRFSGDKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WMX4</accession>
    <name>A0AAV4WMX4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Cdk16</name>
        <name evidence="14" type="ORF">CEXT_746852</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01016438">
        <property type="protein sequence ID" value="GIY83861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WMX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000611">
        <property type="entry name" value="CMGC family protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000007">
        <property type="entry name" value="Cyclin-dependent kinase 14, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF246">
        <property type="entry name" value="ECDYSONE-INDUCED PROTEIN 63E, ISOFORM N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="110"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="429"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY83861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="444" mass="50759" checksum="33650FB08739077A" modified="2024-11-27" version="1">MPSGRSLHQMFTPCFGKGVVHEDPRIGSDGESEEASGASDEVVSPVKLRSRHRRVSERDISKRLSLPADILLPESFLAKQTVSPTLEGPISRTLRRQSLSEIGFGRIESYIRLDKLGEGTYATVYRGRSRLTNNLVALKEIRLEHDEGAPCTAIREVSLLKDLKHNNIVTLHDIIHTEKCLTLVFEYLENDLKKYLDDARYWISLDNVKIFLFQLLRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTSIDLWGVGCIFFEMVTNQPLFPGATVNLQLDLIFGQMGIPTEETWPGITSYEDFRANYLTEKPRHLDGEQKKFPQRICRLDCDGQDLFFKLLTYDPKKRISALEATKHRYFKSLGPEIHKMPDTASIFSIPGIVFTPDPNAAEQDRKRRLERRRALDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWX0</accession>
    <name>A0AAV4WWX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_809771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016934">
        <property type="protein sequence ID" value="GIY87381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17549" checksum="383FC96AC54AEDDE" modified="2024-11-27" version="1">MIMSNGANTRRLLMRENVNGANTRRLLMRENVNGANTRRLLMRENVNGANTQRLLMRENVNGANTQRLLMRANVNDANTRRLLMLENVNGANTRRLLMLENVNGANTRRLLMWENVNGANTRRLLMRESSISPGNFKWKIDLTFEHNSTRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZ85</accession>
    <name>A0AAV4WZ85_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA-binding motif protein, X-linked 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RBMX2</name>
        <name evidence="9" type="ORF">CEXT_790391</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in pre-mRNA splicing as component of the activated spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the activated spliceosome B/catalytic step 1 spliceosome, one of the forms of the spliceosome which has a well-formed active site but still cannot catalyze the branching reaction and is composed of at least 52 proteins, the U2, U5 and U6 snRNAs and the pre-mRNA. Component of the minor spliceosome, which splices U12-type introns.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IST3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016982">
        <property type="protein sequence ID" value="GIY87821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZ85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000218">
        <property type="entry name" value="RNA-binding motif protein, X-linked 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="342"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="403"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00053249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00061455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00064744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00074390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY87821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="455" mass="53315" checksum="8A53FACDC3E1AC4F" modified="2024-11-27" version="1">MNPLTNVKNIIKLNETELARGTVDKKSWHDIYKDSAWIFIGGLSYGLTEGDILCVFSQYGEIVNINLVRDKKTGKTKGFCFLCFANQKSTILAVDNLNGIKLCGRTIRVDHVANYKPPKDNEHDDELTKMLKSEGCAPKPIKAENPSLPVSPVTSQKKKSKKIKKVELPLKRIKKEKVDPSYFKYEFPEQFQASKEKSSTDSESSSNDSSDFRSNHTSRKEKTLPKTSSKIDRIESNFDKKDVEFSQVRTNERKNAEKYSNKRKNLNDYSSNSDYESVEKRRPHYRDNSNDFSLKRKDSKYNKDKYSSDSSADESYKKSRRDYKDLYSRLEGNYKKSSSSDNKLKSKDDKKNGNKEYESHHHHSSSDRENSSHHKRHRSLSEEKERFKRRDSLVKESNSYHRRHEDGRHGNSHRQKNDEPARYEERQDFVEKHNYHSKSRGDRKDYDRHHAQKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZX5</accession>
    <name>A0AAV4WZX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_556291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017022">
        <property type="protein sequence ID" value="GIY88091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11842" checksum="9F451201E6068A1E" modified="2024-11-27" version="1">MGPYFSRNGRSEDALMTIEGGSFARGAIIRAIRILRKRQRATKNTDSFHQRCEGLSLLLISSDENHDSRSIPQPPPSPRNVFPSCYRKTFPLKTSALSFKEAVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1T3</accession>
    <name>A0AAV4X1T3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate--hydroxymethylglutarate CoA-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sugct</name>
        <name evidence="3" type="ORF">CEXT_166322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016967">
        <property type="protein sequence ID" value="GIY87723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1T3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047369">
        <property type="term" value="F:succinate-hydroxymethylglutarate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050483">
        <property type="entry name" value="CoA-transferase_III_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48207:SF3">
        <property type="entry name" value="SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY87723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="293" mass="32045" checksum="99E30017FB2AA6DF" modified="2024-11-27" version="1">MNPFVRIFLEANLKGYCCIACYQKFVFARDEDLDWFHSSCEKQQCTEGPLTGIRILDLTRILAGPFCTMILGDLGAEIIKIENPDGGDETRNWGPPFINGESAYFLSVNRNKKSIAIDIKTSQGRDLIKKIAIKIAPHLIYCSVTGFGSTGPYSTRPGFDVIAASIGGLLNITGPENGEPCKVGVAITDLSTGLYAHGAIMAALLQRIKTGNGQKIDCNLLSTQVSLLINISLNFLNGRKEAKRLGTAIESIVPYQAFKTKDGYIALGAASNRQFKILCEILNIQHYSTDPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBN9</accession>
    <name>A0AAV4XBN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_19271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000026">
        <property type="protein sequence ID" value="GIY91595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10220" checksum="8351D3C914D4A2F6" modified="2024-11-27" version="1">MAKTFKTIFLKIAHQITMQMEHNLFRANDTIFANEPHSVTLARASVFHRTEKKLAHHHEYLEKTVRCREKKKKRNARNNGGKAVPPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF93</accession>
    <name>A0AAV4XF93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Myosin-2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MYO2B</name>
        <name evidence="6" type="ORF">CEXT_801681</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017680">
        <property type="protein sequence ID" value="GIY93611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF561">
        <property type="entry name" value="MIP31562P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0518">Myosin</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="5">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY93611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="20295" checksum="0C40D1340BACDE60" modified="2024-11-27" version="1">MFKVNSFEQLCINFTNEKLHKFFNHYVFALEQEIYQEEGIVYSHITFTDNTPCLELLEKGTDLTYVTKLHQEFELHGNYIKGDDRRRWESEFGITHYAGAVVYTVEGFLKKIKMPNKINCLNLCKNPDLLSVTTNRLKSASTISRTMTKGKPTVADAFRHQLTALVDLLHSTNPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKP5</accession>
    <name>A0AAV4XKP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_272286_1</name>
        <name evidence="3" type="ORF">CEXT_566601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000463">
        <property type="protein sequence ID" value="GIY94973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY94973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16302" checksum="8904523C38120654" modified="2024-11-27" version="1">MSMHLRGSKDMMRNEDEGWWTSRTGLEQKLVILSTVLFIVAFALTITVIVYKNKKPDEVTTVAPVTSPSTDNTTGGSESPTTPTEVPGTTSEASTSPTEAPATTESTTSPTEAPTTTVAPTMDPTTTKHEQKSPEKNEQKSRILMELLSSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLA6</accession>
    <name>A0AAV4XLA6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_557171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017979">
        <property type="protein sequence ID" value="GIY95917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="148"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY95917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="231" mass="26069" checksum="E2DCA711995EDB74" modified="2024-11-27" version="1">MGAEGGQNAVRSSENVQKFAEYFLLPPTSNNRNISNTIDSASGCRVRNKKIRTYEMNPNEDSVQLLDLSIGEASYKTDGISGGENCSCQRTQSNTYTSSTECSSSALSSTKNSGDQGRKHACDVCRNELSNLSSLKRHKRAHYGEKQFVCNTCPNRFARQSHLVDHKRHEAIHSRTKPHHCDYCDFENAHKPSLDKHLEAHHSEHKEKCPVCCNYFYSKKSLQSHECKKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQ96</accession>
    <name>A0AAV4XQ96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_724951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000668">
        <property type="protein sequence ID" value="GIY96518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQ96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13334" checksum="40768AB5CCBCBD9F" modified="2024-11-27" version="1">MTRSAKVRTAASPWKVPRSSNFPVTPYPPSEEGSSLRVFKRNKLEMLQWLASVKFRLGDSRGPMKINTTNPQVRNSSRRNDGRKVLKAIASYIYIPQRPGEQRAVNLIQNAKVHPSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQZ3</accession>
    <name>A0AAV4XQZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_448171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018177">
        <property type="protein sequence ID" value="GIY97555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="21634" checksum="F3E8F53042B83477" modified="2024-11-27" version="1">MSSKVGVLQLYYNVTLHLHRNLVFLRSRAPFVLQFWEQILKKLLPGRPGRHDFSIHNTSSRTSPISAFQFLKVKRNNTRDLVLLHDGWFDAAAEMFMDRGHTKIHLLFNKNSILGEQTHTQKDFLEGVLIHVGWSDAAAEMFMDRGHTKNSSPFQQKLDTRTAHTQKDFFGRGIERSFLIRWKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRY0</accession>
    <name>A0AAV4XRY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000784">
        <property type="protein sequence ID" value="GIY97472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14918" checksum="52C09A64FEE6564A" modified="2024-11-27" version="1">MISLTLVINVRNLISPHDRKILQIKLTSTFQKNLQPFSAESRTPLASARPPTRAPFQELQLPCKLKITFLRNNLSPGKAKERASIPGIKRSPITSVCRHSPFPPLFLYPRLFFSEFSGGRGGRSGNREIADFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWK5</accession>
    <name>A0AAV4XWK5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein SYS1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">sys1</name>
        <name evidence="11" type="ORF">CEXT_23211</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in protein trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SYS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018311">
        <property type="protein sequence ID" value="GIY98570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016973">
        <property type="entry name" value="Integral_membrane_SYS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952:SF0">
        <property type="entry name" value="PROTEIN SYS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031402">
        <property type="entry name" value="SYS1_homologue"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR031402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY98570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="18025" checksum="153923B1CA1E9D2C" modified="2024-11-27" version="1">MRGHFRYSVWDPLLIISQILTIQAIFYVSLGVWIFVTDVISGYNQSLDQIFLYKIISVKDLHGRCLAGSFLLNSLCCSLALWYFVQRTKLCLDFTVTTHLIHLVLCWWYSSAFPSTFSWWLLNIICVTIMCVCGEFLCMRTEMKAIPLSMGVKTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1X5</accession>
    <name>A0AAV4Y1X5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_87451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018635">
        <property type="protein sequence ID" value="GIZ01143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="13684" checksum="6B559A64B5DEB48A" modified="2024-11-27" version="1">MVPEALNNNTGEKGKYIFPGKRAPAFCCVKESGCFAAGAIPPPSVCKSSALGALFLGRGINEAPDPAIKDVTPNVVCRSQKLPQTNSPFCLNDSFPDNLFCGGIIQQHHSNKSRISGERLQLLLRGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1Z9</accession>
    <name>A0AAV4Y1Z9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018516">
        <property type="protein sequence ID" value="GIZ00189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1Z9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11789" checksum="FB76D3E0DC6464F1" modified="2024-11-27" version="1">MTYNSLDENSETFSETVDKILRTFLDVEVIETTFPDFFRGKNREFSVEGWNKKKNSGHFNRSWGYFEEQMEHQECDFRFKMPVQPDTQGSEMLDMISPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5Q4</accession>
    <name>A0AAV4Y5Q4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_85931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018652">
        <property type="protein sequence ID" value="GIZ01311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="18552" checksum="B1E1D34F24030C9C" modified="2024-11-27" version="1">MSIEMVPEWSTVCPDPLRPLIRGIHFRELFSFAAVIQMRRAVRDLQRRDQIACMSVFLPFRDPDKKFRDVYIGMVFIRKGFIFCGCFISGFVCPRLTFFSFAVIQMRRVVRDLQRRDQIADMAVFDQLPFPDPDKKFCDLYIGMDFIRGKALFLRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7N1</accession>
    <name>A0AAV4Y7N1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_35201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001464">
        <property type="protein sequence ID" value="GIZ02480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7N1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14376" checksum="95E5435774037695" modified="2024-11-27" version="1">MLTNQKNYSLKQSNNQRINNKLSFSKSAKGINKTHNINKITGFLQPLLRKPLQIKEEDHCNRKYYGDYKLTSSEVKMVAFRKNSEFYSLFAPDTLFRTLSPRKSLVIGRRHARTISAGKIRLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7W8</accession>
    <name>A0AAV4Y7W8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA-binding domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ACBD5</name>
        <name evidence="2" type="ORF">CEXT_92711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018780">
        <property type="protein sequence ID" value="GIZ02229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7W8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="214" mass="23141" checksum="25EB0A455BF31A21" modified="2024-11-27" version="1">MNGKIKQPLNNNSEDHIEENHSSHYGLLSKDYKNGISREPEDYPTPVNGHNLNGNNDSDSDEFSDTLDRINEDDPPEASLTNGKPVANDNPLTDKGPSIVNMRGGGDHRVGSNEGGSSAGGPSNSRGNQFTRQQRSSDYPLHSGSDARLVGGAGGSRRGGEESTTEISSDMSEQLAMAVIRLQHSMEQVVIRLESLETLLLERRANNNSLQIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9J4</accession>
    <name>A0AAV4Y9J4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein-like 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Gnl1</name>
        <name evidence="7" type="ORF">CEXT_360061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Possible regulatory or functional link with the histocompatibility cluster.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019023">
        <property type="protein sequence ID" value="GIZ04018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9J4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF3">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="6">
        <location>
            <begin position="315"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="539"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ04018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="579" mass="66518" checksum="E55525A79F136FC5" modified="2024-11-27" version="1" fragment="single">DSAILSSLSSQKSSLEDVDVINEQPTTSGKHNTNRYRLIFKKEKNEDVKQRLLLAKEPFDPVPEEELEVCYEDVFAHGSDLDMPKRPVWDFSFTKEELEIREQKYFREYIANLEAKFGEQDLSHFEMNLETWRQLWRVVEFSDIILQVIDIRYPVYHFSPALYDYVTKDLKKHMILVLNKVDLVPAPLVLSWQEYFKKHFPMLKVMCFASYAGMILKEGKRGRRIGNLHMAIAGSRQLLQLCKEIVGDQVNLSSWKEKIDIEAAQIGSSGDTYLDSESEIDSEDESKHIKASEVFNQQNDTSYYEGERYRDNVLTVGFVGHPNVGKSSFLNAICGRFHDYLFCFQVVSVSRTPGHTKHFQTIMLTRNIRLCDCPGLVFPSLVPKPIQVLMGCYPIAQLREPYSAITYLGQRVQLPQILKIRHPENEYFESADEVKWSAYDICEAWAIKRGFRTAKAARPDVYRAANNILRMALDGRTICLAFYPPNFTKEKAMWSEHPGLQEILAVQAYRQKNLEDSQDIPSVCHELNYMNVSEDIEDYCDSESGEDEDSRNDEADSEDSAGAPTSANKFGLLGDDINC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBU8</accession>
    <name>A0AAV4YBU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fanconi anemia group I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Fanci_2</name>
        <name evidence="3" type="ORF">CEXT_234901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001730">
        <property type="protein sequence ID" value="GIZ04399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026171">
        <property type="entry name" value="FANCI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029313">
        <property type="entry name" value="FANCI_S3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029314">
        <property type="entry name" value="FANCI_S4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21818">
        <property type="entry name" value="BC025462 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21818:SF0">
        <property type="entry name" value="FANCONI ANEMIA GROUP I PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14677">
        <property type="entry name" value="FANCI_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14678">
        <property type="entry name" value="FANCI_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FANCI solenoid 3" evidence="1">
        <location>
            <begin position="5"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="FANCI solenoid 4" evidence="2">
        <location>
            <begin position="165"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ04399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="340" mass="39069" checksum="B95957D5FAD515A1" modified="2024-11-27" version="1">MLDSFNDILILGQVYFKTYIEGISSDFSELEWERISGIFAEGLASIFSYINSYHSKNASKFILKICGNESAVVKQALQIILKSIQKSVMKLLSDTQNDVNLKEVVPLLSVIKTLYGLFTKDFNEDLYKWFKQLCNQQVFQNTSISKSFISLCLTLGHQYSNILTFLKEIAFDLHFHLDDIDPDERVRGSPKYDIITPEVSRTVMPNLISNLDQLLEEIEYTLNYMKANAVLPTEFLLLNSIDISIQNMEQGVSTRLADVILVFNEIVQTSVPPDNTCSIIFKAITRFYRILCTLTNYYLLRHTKLKITELHSTFEKLIKLTHTKLTPYVYGFITLSKNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YF38</accession>
    <name>A0AAV4YF38_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_592071</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001772">
        <property type="protein sequence ID" value="GIZ04641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YF38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004993">
        <property type="term" value="F:G protein-coupled serotonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030594">
        <property type="term" value="F:neurotransmitter receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007187">
        <property type="term" value="P:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24247">
        <property type="entry name" value="5-HYDROXYTRYPTAMINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24247:SF202">
        <property type="entry name" value="5-HYDROXYTRYPTAMINE RECEPTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="22"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIZ04641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7518" checksum="8EE255AE01F395C2" modified="2024-11-27" version="1">MNISGGGDKWFASIMIVITAIGNMLVCLSVCLVRKLRRAPNFLLVSLAVSDLCVALLVMPLALHYELAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M445</accession>
    <name>A0AAV4M445_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_125389_1</name>
        <name evidence="3" type="ORF">CEXT_806801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019344">
        <property type="protein sequence ID" value="GIX66846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M445"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX66846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="22735" checksum="2E97F5710BEEAFDB" modified="2024-11-27" version="1">MEGDPFKQRYPPKRPKKAVLLASSDLDKIVADSRIHQIVEEEERALRERRESRLRESKELSAALSQRRQPGHELRKRQYALGTKYAKVELDREAKMETRKNKVLEQAYKRLYEETDRVKYFKTAQSSDLAAKGRKDQMATRVSQKNEEERYDVQFLLGTLRDVDQYESEEQEKAVIKQENKKKECGELDKAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5T0</accession>
    <name>A0AAV4M5T0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_10391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001819">
        <property type="protein sequence ID" value="GIX66761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5T0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="10995" checksum="DEFE0340F6C3A3A5" modified="2024-11-27" version="1">MDSLVNMNGLDPLMKVNGMDRLVKVNELVPLVNLNGLNPLVEVNGLYHLVKMNGLNPLVNVNGLNPLVNVNGLVSLVNLNRLNAVVKLNGMYLLVKVNVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MA07</accession>
    <name>A0AAV4MA07_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Collagen-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_186955_1</name>
        <name evidence="2" type="ORF">CEXT_636871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002021">
        <property type="protein sequence ID" value="GIX69189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MA07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="56138" checksum="EFA492EEDBD4DCA4" modified="2024-11-27" version="1">MTEKLRSVTTTTELVRTISENSNILDMKISDKCVVDIENQGNYFEYLRLFCEKELDIGSKAWLHPIPELAYYIYESEKWYIFLEALYNKFSEYEVQRDKNKYNVENLEDWGKDEKPQEIQISADTFHQFLSKIEVFNIMEYESIKDITATELRVEELNHVLCLTLKHKINIIYKEPYILIKGDYIRMEDFSTNRKAEMDLNDIQKKLLTLLQSGRYKFLNVFALKTLFIDSDATFPGIGMRFFAPKWEIIGTRNINLNGICGEPHLDERPNTVQRGGDSGKDGEPGNPGRPGGSFFGIGEHFVKGCNLTVTVNGGDGSAGQHGEHGKYGLDGTYARLPEGADNTNHADLRKGITSINGFQYKIFGEPGKKGGDGGNGGRGGKGGHPGIIKIIELGDSSEISMHANPGKDGVDGQGGDGGTGGDEGGGIHAGVYIETLDYVAALYGIQKKQDGNLSINIYLTLITKHLVEKMAFLVRMIKEPKTQNQEELFARLIISQMNMQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEB7</accession>
    <name>A0AAV4MEB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_727941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019696">
        <property type="protein sequence ID" value="GIX70726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="221" mass="24602" checksum="945991CDC2BE2442" modified="2024-11-27" version="1">MRKTNYSYVYIGIIIISITVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVDMQARLVVQWQRAPLVFPSTTHKLFCAKQFSKIQSAFPFCPLGPATTVETLAVSRNLLRIECRKYPKLESYEPNNILLVTEYIDMSTLGPKQHNPSVSIKSVGCQTRHFHTSAKVVELDFFFLLHCRMHWRNSPMVMQISPYAPGSNCTLELELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEZ3</accession>
    <name>A0AAV4MEZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_746531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019707">
        <property type="protein sequence ID" value="GIX70993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14527" checksum="45BA47BC2590321F" modified="2024-11-27" version="1">MSGSRERCYRLNTSRTVPLPSVSYTRSNLRSNRHITSSLPDVFLIETHHNLLGLHSSNTTDFCPPTSPSSTERSGERNEDAPPSYEDIVGDDRLIWNEPPPAYHEVADKSPNFLFIWSQIQIVSWSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJR5</accession>
    <name>A0AAV4MJR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ homolog subfamily B member 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dnajb4</name>
        <name evidence="4" type="ORF">CEXT_90461</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019819">
        <property type="protein sequence ID" value="GIX72075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000026">
        <property type="entry name" value="Uncharacterized protein, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="27"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX72075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="383" mass="42791" checksum="B77F253DB78A8870" modified="2024-11-27" version="1">MSSKRTLSIDLKCYKEVVDCRSSVWIDCYDCVTARVILKTCDLFTYKPLFVIVNKNGKLALKYHPDKNKTPEAEEKFKEVAEAYEVLSDKKKKEVYDQFGEEGLKGGMGGGGGGGAGQNYHYTFHGDPRATFAQFFGTDNPFESFFNMGGMGHSGSTIFYGDEDMDVDDPFSHFGGRVGGNPFRSQSFTAGSPNVHRSKPKGQDPPLEHDLYVTLEDIAKGCTKKMKISRKVLLPDGRSTKREDKVLSINVKPGWKAGTKITFQREGDQTPNSIPADISFIIRDKPHLIFKREGSDIRYTAKVSLKEALCGTKLEIPSLSGEKRMLKITDIIKPNFVHRIKGLGLPLPKEPTKKGDLIVAFEIKFPEHLPDTTKEILREVLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLT7</accession>
    <name>A0AAV4MLT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NACHT and WD repeat domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NWD2_5</name>
        <name evidence="2" type="ORF">CEXT_368941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019928">
        <property type="protein sequence ID" value="GIX73217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052752">
        <property type="entry name" value="NACHT-WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871">
        <property type="entry name" value="BETA TRANSDUCIN-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871:SF45">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="29"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="418" mass="46687" checksum="F7147F03F4B54059" modified="2024-11-27" version="1">MSASEQRTVGHESNLEAVKSYLVGNANHPLIIQGPTGCGKTCLMAKLTELSSVWFPTACVVSRLVSLTAESATQHQLLRSISEQCCALYGNTQLLHHLWDYGLGKLLGKVSELRPLIILIDGIDQLADYSNADLQWLPRELPAHVKLIMTVRDNSDELEKIKDIMEESDCFLSVSNPTAEDAKASITQVLESICARSTTSLRAKSNKRKLEELPYQVLQVNDSIRDNFLFDATWLLYKFCGSDPYQLLEDISTYQKTLPKSDIQLELLENVVQLSSYALRSDGSQFFAQMYGRLKKAFSTNACSVPFNKSLYDSSCKPPLSSLLPIGTCLEEPLIPNLTNNCNNSNHHSSPGSESPSSRGFPFTGLYTIKEDKCHVVSISSDRNEIVVWNIYEQAAVRRMTGINQPKDIKMIDIYRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLU8</accession>
    <name>A0AAV4MLU8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein RIC1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RIC1</name>
        <name evidence="5" type="ORF">CEXT_466541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019857">
        <property type="protein sequence ID" value="GIX72537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034066">
        <property type="term" value="C:Ric1-Rgp1 guanyl-nucleotide exchange factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040096">
        <property type="entry name" value="Ric1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009771">
        <property type="entry name" value="RIC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746:SF10">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746">
        <property type="entry name" value="RAB6A-GEF COMPLEX PARTNER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25440">
        <property type="entry name" value="Beta-prop_RIC1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07064">
        <property type="entry name" value="RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIC1 C-terminal alpha solenoid region" evidence="4">
        <location>
            <begin position="252"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX72537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="746" mass="83836" checksum="AB866E0440949E40" modified="2024-11-27" version="1">MKFVSIHKESKLDNQFVRVVKMDSQVLQLSALGDRLLVFCADSHLTLFLLQRKTSPTTFLLVTRLLELDVSNLVFHPACVVSSLLTSLCTETVRWPRKGDESILLNICGRLLLLQQDPVSRTSDVVNNNSQKIPSYGLPTVLASCVENVWVCSHSSKETPHLTEALWIACGAHGMRVGMAAIISERWRKQRAHNFMSKRIMLPVPVYIYPLAVLYEDAVILGAENETVLLPADSYCKHPFCIISRTSQVYLHQILRQLLKRNLGYHAWEIARSCSTLPYFPHSLELLLHEILEEEATSSDPIPDALLPRVIDFIQEFPVFLQTVVQCARKTELALWPYLFSAVGNPRNLFQACLNHGQLETAASYLIILQNLELSSISQQHATLLLDSALEAGKWEILKAIDPSDNDSVPRSFIPPNKYGLPHSTPPVSPSEDDLSFVLGTVSLTRGGFAKSTTVSQKLASAIQDKSSRVQHQDIARTISDPHTIPRRRRVSEHKEKGNSDEFFIDTLLSRHARKLLNSGKLKDLGYFAAHLDFHLITFFTKRKLPKQKESLLTLDTSENSSLWTEDSLAAFDDENFSSLSLPIELDSISEELMSHGPLETEVQLRYLLQLLLEAGCLDWALLIAIILRDVMSVIRVVNSAKQVEQFPNILKHLREGMASIEQWAEKECLGYKNFMILVHNQAKALSKMSSPASSLLKLDMQSTTENFCSDMYDNDQNHHRLSTSSDIPGIEGTLVLHGTSLDKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQI7</accession>
    <name>A0AAV4MQI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_456611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002440">
        <property type="protein sequence ID" value="GIX73737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15533" checksum="EDA72194D897D945" modified="2024-11-27" version="1">MRVLGMRYMWLQNQLLDKGTRIRERDTFKRNTAENSHGASYGTGRQRVKCQIAWDDAPFFPIALSGNELPIMAPSIYRVVLAKGFFATPQQNDTVSIDAINASSRLLSPLRVICPGKLLKQVSRGWETAEKKNLEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR50</accession>
    <name>A0AAV4MR50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome non-ATPase regulatory subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PSMD3</name>
        <name evidence="5" type="ORF">CEXT_130691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020058">
        <property type="protein sequence ID" value="GIX74345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="250"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="461"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX74345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="494" mass="56726" checksum="02C5333125CC1A5F" modified="2024-11-27" version="1">MAIQDVDVEMTTEDGENTEKEKIPKADVEALSLADIKEHLMFIEKSVTSKEPRFILRVTRALVSIRKRLSAKILRKVVTHFYVFSAQQRDVLLGLIDEPMDMDSNGNKAPVRVKNTKSSQQPLLPEQDIYIHLLVLLYLIDCGQPQMAVNCANLLMKKVMAQPQRTVDLIAAKCYFYYSRSYELLGELCKIRSFLHGRLRSAVLRNDYEGQAVLLNCLLRNYLHYNLYEQASKLASKSVFPEMASDNEWARFLYYLGRIKAIQLDYSEAHKNLLQAIRKAPELSAVGFQTVYKLAITVELLLGDIPDRSLFRQPQLRKSLAPYYQLTQAVKAGNLNMFNEVLENLGPQFQKDHTYTLILRLRHNVIKTGIRMISLSYSRISLAEIARKLLLGSSEDAEFIAIRDGVIEATINHAQGYMQSKQTVDVYSTGEPLAAFHKRISFCLDIHNKSVKTMRFPPKSFHKDLETAEERREREKQDIEYAKEMTDEEDDGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXF1</accession>
    <name>A0AAV4MXF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_429551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002642">
        <property type="protein sequence ID" value="GIX76032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9770" checksum="1DD7CAB2BCB6D4C4" modified="2024-11-27" version="1">MVHARPAPESMFIRIVCSKGGGRLTRGSSNIVASAGLLIADFLWAYLVEERVVHLQWRLKVRGSPDLIRTETFWGGGVECMRAEIRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N146</accession>
    <name>A0AAV4N146_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_633001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020296">
        <property type="protein sequence ID" value="GIX77009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N146"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13201" checksum="ECA9D2259F0523A3" modified="2024-11-27" version="1">MVEGLRSPQSKFNYLMPLQFGEYISMIPFYQGCIAGACNTAVTLGICNLKLRSLILRTEMFFDNIMVEGLRSPQSKFNYLMPLQFGEYIRQNPTASRGLRLRKGTPTKKSNARNPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5D4</accession>
    <name>A0AAV4N5D4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_660131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020514">
        <property type="protein sequence ID" value="GIX79613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5D4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043450297" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="8054" checksum="B86B5169A59DF8F0" modified="2024-11-27" version="1">MHRIALSTMRIEARFAILVFLEFLGDIVCGAQIGPVYRAVCGQPLREGRQRSFRNGRDYRGKVIIMITATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9J4</accession>
    <name>A0AAV4N9J4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_410841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020655">
        <property type="protein sequence ID" value="GIX81113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9J4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7760" checksum="C300CD84E0EE0DBB" modified="2024-11-27" version="1">MEHFVDSSALCLTGTATCRSVPGSSLCRCSNRCSQFMPPVTSPHWKGVRLADSYGSVCPRNGPISKMRQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAI4</accession>
    <name>A0AAV4NAI4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_228581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003153">
        <property type="protein sequence ID" value="GIX81677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043562520" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7570" checksum="D316E6B6A72409E8" modified="2024-11-27" version="1">MARRATQTRIASLFALVFALSSLRSHYKRSICVQGPLSGPEECFSPVGFCLGTKHSETTGELEFSQHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAI8</accession>
    <name>A0AAV4NAI8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_578841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003045">
        <property type="protein sequence ID" value="GIX80547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8717" checksum="72FC2B353A2E3C77" modified="2024-11-27" version="1">MVSPGFLSFVPSPPPLSSVLHSPFPISMYPEHCARANSISMYLYQRCPAVARKSLERVSCSLVKMKSTSSEGFGIRRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NG54</accession>
    <name>A0AAV4NG54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_404151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020897">
        <property type="protein sequence ID" value="GIX83716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NG54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16730" checksum="51AA3C12C16143D2" modified="2024-11-27" version="1">MKYSKSLPRIRILTSGMFQAITQNQNPYQWNVPSNYPESESLPVKCSKPLPRIRILTSEMFQAVTQNQNSYQWNVPSHYIELESIPVECSKPLPRIRIHTSGMFQVITQNQNPYQWNVPKPLPRIRIHTSGMFQVITQNQNPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NG81</accession>
    <name>A0AAV4NG81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat and fibronectin type-III domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ANKFN1_2</name>
        <name evidence="2" type="ORF">CEXT_607621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003240">
        <property type="protein sequence ID" value="GIX82454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NG81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061172">
        <property type="term" value="P:regulation of establishment of bipolar cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039269">
        <property type="entry name" value="ANKFN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21437">
        <property type="entry name" value="WIDE AWAKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21437:SF1">
        <property type="entry name" value="WIDE AWAKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="28729" checksum="4ADA325DCBF8E01D" modified="2024-11-27" version="1">MSFMECYGCRLFCSRTKDDVTERTDCVLLPLQIFEMIHMSTYQHIFISRYSRISSILKWTRLWRNIFIDRLSPHQNLLQLNQDSGSFSNFNRKWIVHGGQMRWLMDVLNFARDKQSRGGRLLNNFLIEKADSPCTSPPQSPQHSQSLHTLQVPESKNSPDDSLKPNAEIRRCVSTSRLLMTSGSTDESDTDTYSRQKPPSTLELMDDKSKAYSSETLSVTYKLGACSNPPCESLSTVDTLSMKMMCQKKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHB4</accession>
    <name>A0AAV4NHB4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_756141</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020924">
        <property type="protein sequence ID" value="GIX84028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901981">
        <property type="term" value="F:phosphatidylinositol phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043544">
        <property type="entry name" value="SNX10/11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46209">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46209:SF3">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="142"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX84028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="266" mass="30119" checksum="DCAFDF3909AC3207" modified="2024-11-27" version="1">MGNDSQMTVVSVHSPLIQFSTSGSYYTSYAISLKSTNPCFTHSYSQVRRRYSEFLHLRRRLAAHHPTIKTPVLPPKNYFYRFNDELIEERRSGLQKFLDEVLQIPVYLSDKSLHMFLQTSCSMTKIDEECVGDIPFPQLMDEKPSVGISDSSESSESLNKKQVDTPHEGLKTADLKCESPVSKKSNSFKQKQTVHKQPVSKPCMIPRRQGSLDSSPCSSLSSLDASYCSSLEYNKSRRVSFNENVTVAVVYNQLWNIVTEPIRTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLG3</accession>
    <name>A0AAV4NLG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_460501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003536">
        <property type="protein sequence ID" value="GIX85657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="13101" checksum="9F541A729A9CE68C" modified="2024-11-27" version="1">MFIPQKKQNPRGRNHTYSRYRFFGRRKKGQWDVNQLLSRSEFEIQSHCNFGLNANRLKHLLTNREWESISSHGAPMETGGRFLPRVLGISFRDSSWNRRVLACLFLRLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNP5</accession>
    <name>A0AAV4NNP5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_283781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003561">
        <property type="protein sequence ID" value="GIX85999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12556" checksum="FA10D23344CA7A02" modified="2024-11-27" version="1">MLMALHISWMTLAGSPVNRSSWVRAFRACVATLSSSSWVALSSISRTLSMPPPSSPGCRRPPPVPQPPSQCPSPPPAPCPWSGPEWRWSGRNGCRWEWVRLPWVEHSLFFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVH3</accession>
    <name>A0AAV4NVH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003701">
        <property type="protein sequence ID" value="GIX87629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11052" checksum="7E2BA2ACEA370328" modified="2024-11-27" version="1">MLAEKNFSLTLLEVNVVWVRVEFPCVVFLTCGYLLHPGPTVLTHPPETCSQSIAGLKFHEHNEKVEEKLKETSMNKRLDFCKWVIKWVAALIQVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYE3</accession>
    <name>A0AAV4NYE3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_393621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021356">
        <property type="protein sequence ID" value="GIX88760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15621" checksum="D55D02ADD07DCCC3" modified="2024-11-27" version="1">MGGKLFSNGSQIMLGFLAVKRWMHLQSRPCFCHNTILTSFTVRWPDAQLASALAFSTTEDWRRLLTDLQQHLNKMAVSSSVPCPLCGDDSMNGLLICSKLKDIGNVFSFVFSHLYWAARQSMHGRLAQVGCRILKKNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3V7</accession>
    <name>A0AAV4P3V7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_49024_1</name>
        <name evidence="2" type="ORF">CEXT_586821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003961">
        <property type="protein sequence ID" value="GIX90665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3V7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043730394" evidence="1">
        <location>
            <begin position="18"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="342" mass="37706" checksum="C26A06B176A9E3B6" modified="2024-11-27" version="1">MVSPLLIFVLFAVAVQSSPTSYQPFNAIKEISDIGNNLDPLESANRKALQNNKILDCDVEEILKTVGLNELQNLIEAVASRKGTNPFAIMKMLYKRMKSHEEREENLMISLDGIPLPDLSSSPVIETPPQAKITPAAGHTPYSLPSNDPMSTNDEEDTKVVIIPVAPEAPTQNRFPPAVVPDIKIKNEAPFIIGPPVAKMNHVLPVFPVLSPMKSNHLRPPPLGTTVRVNSGDARNPVNRDISVTVSPLMTIIEALRQAEIKYQNFLGLHHDMDVITFTHSLAIDCYIVNRINDVVKSDDSGWKITIMDRDGQIVYDGFCLPNAKDVLVKPGTVIYLSYVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5Y8</accession>
    <name>A0AAV4P5Y8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_767221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021577">
        <property type="protein sequence ID" value="GIX91370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5Y8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14466" checksum="37B5B712A46B92ED" modified="2024-11-27" version="1">MSTGPNLCRSYQSRGLSSLQVDCSGSFTQRIINVLNVLAPSLMTLPGRDRFVREQGTICNSQSINLPSSPKVRLGSFGTLFDNDRWGISFVFMCVCLAKEMLVVLSLYKLPLLAVLLLDQMLRLVSFVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA87</accession>
    <name>A0AAV4PA87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_128221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004142">
        <property type="protein sequence ID" value="GIX92606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9818" checksum="57F6C2C481B71C13" modified="2024-11-27" version="1">MEKKEIIWLSDWTDDLRVQSPPFLMDGFDEVDHHCLVTLCASSEIVFWFSSFPTGINMVQGNCILGCMAGISLDCISGSIWRKKSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDH1</accession>
    <name>A0AAV4PDH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004345">
        <property type="protein sequence ID" value="GIX94191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12727" checksum="7266228EA1C811EF" modified="2024-11-27" version="1">MQLTVTATENNRKNKMASTSSIFDSLYVANIEEWKGSYVDIIKFITIVRLRFANHISRMDPSFLTFKIFNFISIVIRIRGRPKLRWTNCMEEDFKMSGVANWRTIARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PEW7</accession>
    <name>A0AAV4PEW7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_294721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004392">
        <property type="protein sequence ID" value="GIX94548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PEW7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10552" checksum="223CF10393208870" modified="2024-11-27" version="1">MRRKQPSILKLKGLDTIDKFSQGNLAIAYTNGSSDKFFNKGSTGIFSYFQMEISQYDSTNIPAGNKSINPAPFQPAEIAMPQTMTLSEDLGTPAISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PL29</accession>
    <name>A0AAV4PL29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_215241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004703">
        <property type="protein sequence ID" value="GIX96846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PL29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10931" checksum="A53BEA71FD964073" modified="2024-11-27" version="1">MSYGEKSSREMMAGGMDFCSADRQGPFQDPLTPLSSDQIGQKQSPDYPSARKGYRKLPNGTFLSPYVPATHHRPIYTRSKGSHRKSRRHYSATEGPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRQ3</accession>
    <name>A0AAV4PRQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_214508_1</name>
        <name evidence="2" type="ORF">CEXT_753421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004991">
        <property type="protein sequence ID" value="GIX98978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="218" mass="24246" checksum="9FE4D002CB5CDFEC" modified="2024-11-27" version="1">MAKSFQNGIVILSPDFKLILAVISSSVMPLVMLFPAYIFAIYYTVICRYLSNILKNFLKTFGAITNPNYVVTVKQYLLIRKLVMEADSELSVLMFISTLFNSCSLYVGITCLLHPGDYLSLGGISAVLAVWILFAISFTSFCDVKTGSSIHELSSSTWDKVQQLIHAGEKLTSSQKRLLNVVEKDLTMTVWKVTSVKRSFILATLGTIVTYSILVDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTK8</accession>
    <name>A0AAV4PTK8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_13423_1</name>
        <name evidence="7" type="ORF">CEXT_562361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005174">
        <property type="protein sequence ID" value="GIY00397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="123"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="244"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY00397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="353" mass="39992" checksum="5160F62037C6A15C" modified="2024-11-27" version="1">MTKFLRIVPIREFLAVVGGEARLPCNIAIPKEPDIISLILWYREAPKSPIYTLDFRKGLPNDAKHFPGKMLTGRAHFDTAEYPPTLKINPTYVEDEGVYKCRIEYRRSRTVTRPVKLITIVPPQAVVITDDRPQKLKRLAGPYDEGAYLSLRCEAEGGNPAPIVTWWKDGSLIDETYFRTSQGFVRNDLVILELRRSDFMVELICQASNTNLTQPINTSVRIDLNSIETTICTYYNSSKPLKVGDDLRLDCETSGSRPPAKIVWWIDNKLVQNEKQSFFTNRNVTYSSIHLSPGIDDNGKIVICKAENPALPHSDMQDTWVLNIHFSPEVTLQLGANIKYSTIKEGNDVYLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0C0</accession>
    <name>A0AAV4Q0C0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_801281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005349">
        <property type="protein sequence ID" value="GIY01637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0C0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8954" checksum="630CFA9D4F868628" modified="2024-11-27" version="1">MFHKWRISVAQGGHNSSHCLLQVMDSTSSAINHVQRKELLLLKHVDELGRAGEQFSVPNPHFNPRVKSMNFVMSSLENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4U8</accession>
    <name>A0AAV4Q4U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein CG43867</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CG43867_3</name>
        <name evidence="3" type="ORF">CEXT_498781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005555">
        <property type="protein sequence ID" value="GIY03212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22903:SF8">
        <property type="entry name" value="MAX-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22903">
        <property type="entry name" value="PLEKHH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY03212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="460" mass="50679" checksum="56B0BD3274398359" modified="2024-11-27" version="1" fragment="single">MTESEPPPPPSLPHPQRRLSLLPLLVSAGGGGGEPRGADGVVPDGGHPPPAHQLEAEVRADEDDFHQVSTGDHRTAAVLAREERREEEARQKIQLLEQRLQGTGDSYKDCVANSDQACKDQIISNLEQQVEEQKKLRILDAKKVEAKASKIKEWVTNKLKELEEQNFQLREENKKCNAQLEVLKKRMSQMSQPKEKNNAEQDSSRGSWEDQGSSDDAPPLSSISSANQRANYINNNEPSYSSSMPVVEGNKKSSSWVSAQQARVDQWIDSSCQVSMSRRPESEEADNLQAIGSDAMVEAGLPPMVPPHSATLSTSPFSQTSTSRTSDSKKPVSKKQHSRSLPRETTRNSSMQVTNIPSSTSRTTTTQTNIENDLNSSNKASANNGTSSYGNIYGSLDRKLKMLNVGNGYAGGERRRTVQTSNDLHDYAEIYTPSKEIIGGLDPDVDIRPPTPPLHRFPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7G0</accession>
    <name>A0AAV4Q7G0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Retrovirus-related Pol polyprotein from transposon TNT 1-94</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">POLX_1408</name>
        <name evidence="1" type="ORF">CEXT_130001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005820">
        <property type="protein sequence ID" value="GIY05257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7G0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="10007" checksum="C627C97B6933039C" modified="2024-11-27" version="1">MDISQYGKFEDIIKVFDLINEQQTYTPIETNYYKNEGEDELIPNKTQFRQDIRALLFIINITRPDISTAVNLLSRRNEKPRKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7J3</accession>
    <name>A0AAV4Q7J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPOP_2</name>
        <name evidence="2" type="ORF">CEXT_705531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005692">
        <property type="protein sequence ID" value="GIY04284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12862" checksum="7E49070B50FBD245" modified="2024-11-27" version="1">MEEGKFKNSTFLIDDMKSLYSDPALSDIKLRTETETFQAHAAVLSARSPVFRAMFTTDMKEKNNGCVDIPDVDNDTLRQMILYMYTDQLEFWSGKMQLCYTRLLTNTKLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA20</accession>
    <name>A0AAV4QA20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_123571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006008">
        <property type="protein sequence ID" value="GIY06878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9325" checksum="754B081D47087F22" modified="2024-11-27" version="1">MIRHDRIDSCVFAHDFAFDFISAWRSRIRVLPPALQPSNFQAYTYCFIFPFMFSGIEEQVFNPVTQLFEISFAFFERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBI4</accession>
    <name>A0AAV4QBI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_530021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005832">
        <property type="protein sequence ID" value="GIY05360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16303" checksum="94DB8E614A75DBA7" modified="2024-11-27" version="1">MERLAEDFTEETLCMLTRGERLRHLFRQWLLLHTTDHHDGGLHQDLQSCQRPAEAQGEGGCELAAMRKSLDTTSTIPLKSMQSKSAPSQSRTSPRHHRQTRGLMIKPKPISKTSRWQRPKIYKQKQSHSRICKAQGAELWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUF7</accession>
    <name>A0AAV4QUF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_8861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006686">
        <property type="protein sequence ID" value="GIY11726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10263" checksum="0DF36228A7E5EAB4" modified="2024-11-27" version="1">MDLNNTSATFSHFLQPYMETTATTMAMDCMVATSSFEGYGGNFSTLPNSQQQPNGVLKDVIGDQLSTEDLHFGQPTKRYTAKTFPVKGPKNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0W5</accession>
    <name>A0AAV4R0W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_412201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007132">
        <property type="protein sequence ID" value="GIY14699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9482" checksum="3EB7027EC0CEE0E2" modified="2024-11-27" version="1">MADAFLSVPFQITVPRVEWRSITRNSCDSYHRMHQKWEALLQLFHIASYLGQYFPPMTRVTGMQQDFDERAGSGVGAGNQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4Z5</accession>
    <name>A0AAV4R4Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_745811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007267">
        <property type="protein sequence ID" value="GIY15681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12754" checksum="E757E5F8C1D61E45" modified="2024-11-27" version="1" fragment="single">EDVIVSGSNLEKFMIMEKLNSPPSKVSRNAPSEVSSLNDIERDDKFLDIHGLIPEVIENIHALQSGVEDKIGKMNSIDLCPVTNCTKYSPITTITNNNTTSYKYNTRNMQKLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7R4</accession>
    <name>A0AAV4R7R4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 2U1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CYP2U1</name>
        <name evidence="8" type="ORF">CEXT_502871</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007457">
        <property type="protein sequence ID" value="GIY17054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7R4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043405536" evidence="7">
        <location>
            <begin position="29"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY17054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22718" checksum="8CAAAD9C1D0963D3" modified="2024-11-27" version="1">MFLSGQDSTLASVSWLLLLMAKHPKVQQKVCDEIDRVIGRDGAVYFSEKGNLPYTTATVFEMMRYISLSPLFPNRYVLDSFEFHGYTIPKGSHVICNNWAISHDPRYFKDPMTFNPERFLVENGTKFEKVKGYGPFSFGKRNCPGEGIAMMTMYLYFVSIMQKFYIRPKDDQPPDMKPVLLSGGLMPKVQPLRFIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBK0</accession>
    <name>A0AAV4RBK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_778191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007526">
        <property type="protein sequence ID" value="GIY17600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13410" checksum="6C6B4B1F744A149F" modified="2024-11-27" version="1">MSVWSRGVDEYRLRFATSRAHPRNRPSSLKDGRHNHRPSKILQHSSGTTHLLDMEQKSRNTKGLPSIIRTNTLSLLTSLLTLTCTYPIFSLCTESSLILLTFEQNLILRHLGCSRVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBY2</accession>
    <name>A0AAV4RBY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007577">
        <property type="protein sequence ID" value="GIY18114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10808" checksum="A553599501F114BC" modified="2024-11-27" version="1">MKQRRRQTINAPTLHVVGRPPIFDDKGSSVIGSSPANGAHGERGFGTAAFHRDRDQNVRINLHIHEEKRKERGAGVARVILFFFFFFSNTLQKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQF5</accession>
    <name>A0AAV4RQF5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_403831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008136">
        <property type="protein sequence ID" value="GIY22332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQF5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8283" checksum="AAB23534C7628567" modified="2024-11-27" version="1">MQNFAPMTLFIVCKPLPQRLPIRRSFKTEDIANLHMRNCVHKPALKAHLSPKKNPTSTTSPYNYTPKFVNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYB0</accession>
    <name>A0AAV4RYB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_63411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008547">
        <property type="protein sequence ID" value="GIY25472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="8053" checksum="A763103F4AEB9175" modified="2024-11-27" version="1" fragment="single">GASNSSESASSDSYDVYSYEDASKKSGSDESSDSIDYYDYYNAASNSTESSSASDSSSSSSSSDSGGGGLLGGGGLLGLGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4F8</accession>
    <name>A0AAV4S4F8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_288581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008810">
        <property type="protein sequence ID" value="GIY27380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4F8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043573732" evidence="1">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12522" checksum="3FE0F5E90477093A" modified="2024-11-27" version="1">MDSLSRRCCVCLSVFVLFVLVSASEGGITGHSGIVMHVNKYGHFSGHSSHYDYRFYPEKSLLDHLIDHHHPYSPSLEDGYPYNYLEDHSYHGEHDPLYYYQHDHYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S509</accession>
    <name>A0AAV4S509_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_491761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008829">
        <property type="protein sequence ID" value="GIY27560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S509"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12193" checksum="79005147854C31DE" modified="2024-11-27" version="1">MIATKSPDAPTCLSQMTTLQTEKEQSKVNSASIVDSNNIEYISPPSRWADFISRRARASGLGKTKSRPTYFPSHLVRTTYFIHYEVQKYPPLGSKWKVVTLAALLSGTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7A0</accession>
    <name>A0AAV4S7A0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Dusp3</name>
        <name evidence="10" type="ORF">CEXT_710501</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01009147">
        <property type="protein sequence ID" value="GIY29869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7A0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033549">
        <property type="term" value="F:MAP kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020405">
        <property type="entry name" value="Atypical_DUSP_subfamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45682">
        <property type="entry name" value="AGAP008228-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45682:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="9">
        <location>
            <begin position="109"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="7">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR620405-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY29869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21038" checksum="2424B175E87579AE" modified="2024-11-27" version="1">MFSSKSRKEPLCTMEELRNICLFPTGGIQEFPTENSDEVYPGIYIGNEASAADVNQLKNKSIGYVLNAAYGRDKTLNMVEPLAPKDYALAGIQFLGIPAVDCMSYPLDRHFNQAITFIRECLHSGNNVLVHCKQGISRSAALVLAYLVAEVGMSLQEATRAVRNRREIMPNDGFLVQLCNLNEVINRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMH9</accession>
    <name>A0AAV4SMH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-sulphoglucosamine sulphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SGSH</name>
        <name evidence="5" type="ORF">CEXT_184561</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009873">
        <property type="protein sequence ID" value="GIY35194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052701">
        <property type="entry name" value="GAG_Ulvan_Degrading_Sulfatases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751">
        <property type="entry name" value="SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43751:SF3">
        <property type="entry name" value="SULFATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="4">
        <location>
            <begin position="12"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY35194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13050" checksum="86747B854571D32F" modified="2024-11-27" version="1">MGLRAALHEDSKNVLLIVADDGGFETQVYGNPVCKTPHLDKLASKSTIFKNAFTSVSSCSPSRSSILTGLPQHQNGMYGLHQDIHHFNSFDEVKSLSKLMKMKNIYSGIYTFYISSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQ78</accession>
    <name>A0AAV4SQ78_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_475851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009791">
        <property type="protein sequence ID" value="GIY34640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQ78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="1">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY34640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="26451" checksum="C7FB07043E3B16AC" modified="2024-11-27" version="1">MASKNDKVFTVTWSIEGISYFKYKDVHSANFYPISKKDERFFLRLSMEIEDNTNLVSFQICNTNDNPEGIYEEDTTEIDFELSILAVDGSPLISRKGTIRSFSEYRNGFLDFVERNELLLNRKDEFMKNDTLTLRCRMREREMSQRVASKRDPLLEMRLFFVEVEDEEKIRIEIINEICVDYCKCKFSILDINGMAVESYEDELAFDCEADVEKHQLPPFISKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZY3</accession>
    <name>A0AAV4SZY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_272601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010132">
        <property type="protein sequence ID" value="GIY37173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13679" checksum="81EE276E5D86FDC1" modified="2024-11-27" version="1">MACSEGRKIPQFSNRCFSLVARSEPNSQKHLVGLLTVAQKVLLQKAIRDFQQTEPFSPKTTTSESIPARKTRKHTVQVKMNNAVFGKENTNQYMTHKVVRSEIPFPSGQINTKQPHILKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0J5</accession>
    <name>A0AAV4T0J5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_346081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010430">
        <property type="protein sequence ID" value="GIY39224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0J5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10308" checksum="A851329E08D6FB03" modified="2024-11-27" version="1">MKPKQKAAIQRKKISAKALTHKESDAAAQIDGPGISEVFGISEIHAFVKEKGLRQLDGEEVSGVNGTPDVINEVNITRTFPRLLFRRKLLRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9A9</accession>
    <name>A0AAV4T9A9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_185709_1</name>
        <name evidence="2" type="ORF">CEXT_487271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010769">
        <property type="protein sequence ID" value="GIY41866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9A9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="583" mass="67104" checksum="5D6F3ACAF02116C2" modified="2024-11-27" version="1">MVTVTCLAGTDEDASHDLKRVQQTTEKPAPYTPQPTPTEKRSDQYVDEYEETEERIELDPGHAEPQRHKPQLQDEYHEEKTIEYLDEPKTNEAGTLDQNPANVEIEKDKNEAFKDYSHHIDNTQTTIPNTDYNHETGAESQKYHRQPVKEAPTYSDEPGYETHHDQSKTNHLPVRTRKDGYSYKHEKRPSYEAYEAPQTSHYYPEDDKEYHVSQQEQTIPNVQEETVKESNPSADDYEEYKNYHPGKENEHYTKRIILPQIAEQNSHSYHQENYHNQDFKEHSYPVNENPSALKYEYEGDSSRGNKLEYSKTSDNYPVQAPVSHPYVRVVEEPHQSIPVRAIEKAVLELNADVYKQLIEDKSPGRRIVAIPINQLHNDPSDRAKSTLHSNSGKPHGILHIPLDGESQSTIDLKNLPLVLQIPHDRNANYHRPQAIYQEHLSQDKHPSVYADGSQIPVVSITKSSGQLNKNKEYAKSKWIPMSPSWSNQAQRKSSHGNNSPIRESPKLVIHRVANEKVQQTLHSENSEPVADLRKHLGASASNVSSRTKIMKSKMYTLKASPTIRNTKDSRYKPEQRMHSLTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THT9</accession>
    <name>A0AAV4THT9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_750691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011219">
        <property type="protein sequence ID" value="GIY44962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THT9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="30754" checksum="428BB0D21CDD5AE9" modified="2024-11-27" version="1">MPYPYKSAAVRRRHQKNSSGYAYEEKYPSAEAELHIKTETTSDIEVENPTSDRKNEPTSYELNSNYLIDTYASHELSRASLREELSQFDTPEIVPVITTDDESSPSGSVDVWTKYYLQFTKYLKIRDKILAQIVFGNRMNLPLWWIPTSIGGFLACSAPPTYLSPLKAAVSASTEVAYSAPAAAYSAPAAAYSAPAAAYSAPAAAYSAPAAAYSAPAAAYSAPAAYISPLKAAVLSRKAAVAAKKRCFSKRKLMFQLRELLFQLGKLPKKSSKICFKVENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TP33</accession>
    <name>A0AAV4TP33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_169271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011473">
        <property type="protein sequence ID" value="GIY46727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TP33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17042" checksum="EA6A0A32A03220A6" modified="2024-11-27" version="1">MRCSIFGAIKRPGLTEVVIVLSAGQLSHGLTQKARMPPIFKKHGCVCIKSHCCVYLLIYTISISIVIIAERLSKPLRTHPHFSPKRAKAIILDEQKASLGYCPHSNDDSVNKTPPLQWHERRIHLQIRRLSIGLCTKNLPIFPEEFIGLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQM1</accession>
    <name>A0AAV4TQM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_375991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011394">
        <property type="protein sequence ID" value="GIY46278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005312">
        <property type="entry name" value="DUF1759"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03564">
        <property type="entry name" value="DUF1759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7981" checksum="9552B26460F36DCD" modified="2024-11-27" version="1">MNSRDQKVKLPTLYDWIETQLRALESLGVTTEKYAAMLFPLVESCLSEEVLRAWQRNNSYSDKRRIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1C2</accession>
    <name>A0AAV4U1C2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LRRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_133638_1</name>
        <name evidence="5" type="ORF">CEXT_347351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012129">
        <property type="protein sequence ID" value="GIY51576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1C2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF210">
        <property type="entry name" value="CHAOPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="LRRCT" evidence="4">
        <location>
            <begin position="123"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY51576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19903" checksum="A8719355EE550F39" modified="2024-11-27" version="1">MHIPTLGEEISENLSKRLEHFFMSNTHTADIGDDVLRNFNNLLEIKIRNSQVTNLKRTMFPFPTKLQKFDFTANLLQTLPDDLFTNMPHLKVIRLGENRISVLSHSVLGNVYQQLDFLDLTGNPLKCDCSLQWLEHEDRKVVAGNCVLPEEKRGESLTNLNNDDFKECLEDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5M3</accession>
    <name>A0AAV4U5M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_77691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012318">
        <property type="protein sequence ID" value="GIY53032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20904" checksum="CDA53443C47F03BC" modified="2024-11-27" version="1">MQSTGRPVKQNEHTRSVCHEARVWPETVRRRQSASAIDLLYRYYRPAIDWFDRTSRDCNRCLLVCCGHRLRDARRLVSKLGWPNSWISLRSAAQKAAFISSRFSSQGGGKKELSTECFPRVPQAFKYFSVTMATSPNDQWTLFSALRATHTAFQKVGGLFYVPRCKEPERRQRLTLKLNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDE1</accession>
    <name>A0AAV4UDE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_212911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012673">
        <property type="protein sequence ID" value="GIY55783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10757" checksum="0C646B29946E1BE2" modified="2024-11-27" version="1">MHGNDQRSIKTGEKRGWEEEYDENDYVYRGLHSKDSFRMVETFVIWREIELHLGSFRRKIIPEEFQLGFKIFSQILLCTCEMLIKELVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHP0</accession>
    <name>A0AAV4UHP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012906">
        <property type="protein sequence ID" value="GIY57427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8196" checksum="A79E590F77F6286B" modified="2024-11-27" version="1">MILPPFLTLQTENGRRDVRKGSAIVFDPIVDTRGKQNTQQKRCDAATLKYIHGLQRKKKLRFSGRGGIAQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJA2</accession>
    <name>A0AAV4UJA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_421841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012929">
        <property type="protein sequence ID" value="GIY57600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9765" checksum="7023FA547AA7DE95" modified="2024-11-27" version="1">MGADHNNPVTCESKQVTRGRPVPLQKLVPKVPGSTKHDAVTQKSNQKNLLLYYGADHNNPVTCESKQVTRGRPVPLQKLVPKVPGSTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTS7</accession>
    <name>A0AAV4UTS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_132591_1</name>
        <name evidence="1" type="ORF">CEXT_266901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013427">
        <property type="protein sequence ID" value="GIY61085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UTS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="22244" checksum="BCDD97A6E1968F60" modified="2024-11-27" version="1">MARFFICGELLLDYTDLGTQPRLLKRGATIRLRLLKAKDEFTLQAKSFGHEKASEEALVQMPFTRIETKTFTLSSGLKSVIIPNTANNGVQIPMTAYTLSYKNDLYTRNYLGVCSDLAQHSINVTNTKNTKTTPISFFDLTQDFSASNPFMNVARSGDYIDEFKLWRRSSGNDHVISLYGNEIAYRNRQQQKRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUG9</accession>
    <name>A0AAV4UUG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_280531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013503">
        <property type="protein sequence ID" value="GIY61702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8205" checksum="8558AE87D0DA0FF3" modified="2024-11-27" version="1">MGDPHSACPSNDIRQGWGDDFNHWMATPAIISQIAFMSSGRLAFMNHSEYGKSNQAQSYCPPQVCYNQKHSNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UV01</accession>
    <name>A0AAV4UV01_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STING ligand-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_636752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013496">
        <property type="protein sequence ID" value="GIY61647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UV01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061507">
        <property type="term" value="F:2',3'-cyclic GMP-AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002218">
        <property type="term" value="P:activation of innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032481">
        <property type="term" value="P:positive regulation of type I interferon production"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12100">
        <property type="entry name" value="Stimulator of interferon genes protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029158">
        <property type="entry name" value="STING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038623">
        <property type="entry name" value="STING_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055432">
        <property type="entry name" value="STING_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34339">
        <property type="entry name" value="STIMULATOR OF INTERFERON GENES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34339:SF1">
        <property type="entry name" value="STIMULATOR OF INTERFERON GENES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15009">
        <property type="entry name" value="STING_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="STING ligand-binding" evidence="2">
        <location>
            <begin position="163"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY61647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="338" mass="38845" checksum="4EA5AF908BFEBE65" modified="2024-11-27" version="1">MPIVKTKARSSTFMFCLLLFIAFISFVILSWKNDKLKNVLDFTDFSIFFALYSALTVIILTSIFHLVFVLATENWFGNEKIDLPIELWKHIENHKPLLFGILLFIFGSCCILPFLELRHILDFLHLICASLLFASIHALFDYDDVDLASSQNIEKSIGTLWAFGAYSAFYKIVLKDIVTRMRKFENEHKITLLVQELVIIYPLSCNANGSLNGRDGKITYVGKLDEIMDDQGANLNRSLSSTVYCIENEHIDTLVRKNIYIAAEIPSPLATLDEMKLVMNNVILKYHRDCFMHTLSSLIEGSSCIILEYDDSEPLHSFLISRLRGRRESYQEKPKEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWM1</accession>
    <name>A0AAV4UWM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_193171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013574">
        <property type="protein sequence ID" value="GIY62084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="241" mass="27384" checksum="B6B96DBD26B82E95" modified="2024-11-27" version="1">MQPLNRYWKICTIQTLLLPPIDTRLFGSSLVAADRNANGSGFLGQFGISTCGWTRWTIGSNGFQRFFELGRYTAATQPVAEKDLNAATQPAAKRDLKRMLLNEDDCAERVIPAARKDLSKMFEEPIHPDTSQSTNMSKHTEDFLCWKRESWTMKNWTIPNRPRRHAVVQQTANDPRLLAVAMILECKTVLKPIQRKGCIVSSLQKLQRKKRATRGYRCGVEKNFGRVSCSRKIGQSFLSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0A4</accession>
    <name>A0AAV4V0A4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_503461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013763">
        <property type="protein sequence ID" value="GIY63617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0A4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8661" checksum="E8CF99D05320BE6E" modified="2024-11-27" version="1">MDSSIDQARMDFKFKTILTGNEQKTSVTGLKYTSDRVLSSLSTSPKIIQKVKFDQSLFFQNPTKTGRGFDLFARYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5G3</accession>
    <name>A0AAV4V5G3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_171721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013948">
        <property type="protein sequence ID" value="GIY64983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5G3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9162" checksum="20A00022695E201B" modified="2024-11-27" version="1">MKISIHGGEIIKRTLQSNISNESPFTLDSFVLWFMPAPEEALRRKDAKAFSAPTIMHASSDGKLRQKSPLKMRQWRRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V822</accession>
    <name>A0AAV4V822_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_405091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014066">
        <property type="protein sequence ID" value="GIY66061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V822"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15461" checksum="00C3721F37947448" modified="2024-11-27" version="1">MLFTTSFVSFVSFENDFRRGIFVRTTALKTKVDGVERGPWSGGSKRVCPNPTQDASLLLIVGAPLEREIIIPSTNEGAEVRHVRSPEIHQLTVRYPGLSGNGGGGQHLADDWEQKQHAAKKKESETIFFHLPAAKQYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAB4</accession>
    <name>A0AAV4VAB4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_529941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014158">
        <property type="protein sequence ID" value="GIY66839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9371" checksum="ADAD6152074A4F8B" modified="2024-11-27" version="1">MFIFESTAGCVCLALINVKKTSAMVAVLIVCDAADIASTMMTCRSENYSSSRLKVIAVAVRSVGVAGERLATTKPPKCACRRSFLHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAJ8</accession>
    <name>A0AAV4VAJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_319671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014192">
        <property type="protein sequence ID" value="GIY67048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16220" checksum="28F1D4F8B6557C37" modified="2024-11-27" version="1">MDFKQFWKLSNILMDFKQFGHCHSHGFQAILVIDILMADRAAWPHHSHDFKSNSVNIFESSSYKHPKDTVIVNSLGIVPFRHEHHSPVLTNSSTTLFHLRRKRRALSLFLMLSLCYPERNHAVTSGGVKRGSSLSSDLQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBF0</accession>
    <name>A0AAV4VBF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_101521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014156">
        <property type="protein sequence ID" value="GIY66825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14015" checksum="7BEC13E0367645CD" modified="2024-11-27" version="1">MHCNALYPAHVPLRTTIIICSASSSREKPRWRTTAINGLPLTVRSRLFLSSLSHSAVTPASQCVSQQQSSDCSNPQLDLKLLLQFNNVRAKHQAWLGGFAPETCQHPLMETLHRNCFSYGVKGQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBT8</accession>
    <name>A0AAV4VBT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_16071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014279">
        <property type="protein sequence ID" value="GIY67735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13959" checksum="6FD36DACDE36BB27" modified="2024-11-27" version="1">MKRIGEEELLSLHVACHFKCRQTQFLSKPRKPCGEDERGPYTYVRRIPDDPGLLPLGSLRQPGRYLRSPVAYLCWNAKWQRKKFFLVGGRRCEGELNAEKRMLSRHEAYEFQVGVGYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBZ1</accession>
    <name>A0AAV4VBZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_342271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014234">
        <property type="protein sequence ID" value="GIY67394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16305" checksum="2C07738929C98E0D" modified="2024-11-27" version="1">MPLALTFPHNSLFSFKRIQNPAKSKRPTRPDYIIPDTITGFFLKLGHPFPANSEERESYALCLDTLQHIRLISVANLYGGSHPQLRPKSIPRKLMLPRDAFELNFPFPSIPPQPKVFPFAPITALLLLPEKSFEMCLHWQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJJ7</accession>
    <name>A0AAV4VJJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_378371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014555">
        <property type="protein sequence ID" value="GIY69615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043371781" evidence="1">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7860" checksum="B7994A22FF844E21" modified="2024-11-27" version="1" fragment="single">YPVLFSNMQHFCFCGAICLILVAGIYAAEEKQSICGKTEKALALFELAEELFFKANELYPTCGKCAKAFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTZ7</accession>
    <name>A0AAV4VTZ7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SLC9A5</name>
        <name evidence="12" type="ORF">CEXT_62611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015102">
        <property type="protein sequence ID" value="GIY73568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF98">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="245"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="383"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="491"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="528"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY73568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="539" mass="59589" checksum="5BF334C36C3FC338" modified="2024-11-27" version="1">MANRFRMHRIDKVEQFILAYGGLRGAVAFALVLIVSDRIIPTKNMMVTTIIALVFFTVFIQGMTIGPLVRILNVPTKNKIKLSMNERIITRSMDHLMAAIEDIVGQTMGNYHLRDKFKYYNNKYLRPYLTREHANAEPKIFETYSKLNVADAMNLVKSNSNLVPVAANGLGTSLSSIFRTYTQINMDKSPSDEKGNFLTADIPRNNSSFLNVDIATLEYSPSSKDLADAQLHHILSDAMCKPVRRKYTGREDPTHRRAADETRTRLQIRHMLNERLPPRRLNNLSSTPGSSKRGAAAPPDSSEHSERSTSSADANNTKGLISGVKKHIQPPTLRFSVADDDEPSDTPTPMPTQTGTAREEPLSSYSSLLDVSSAQEDDGIVFTVHGQRTPSPNTDAKDGTSESDNDDTSLRSLPTQTLTELQLPWKRDVETGVGGPHDSNTYVHRQQEFPSWVDNSEYYSFESPSNTLLSRIGAASKRVSAPSVFDIFQASSPDGAAAAPGDSNTDSANTKEVVIEIEPNGVAQRSKVVREEDSQATRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W1I8</accession>
    <name>A0AAV4W1I8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_692581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015500">
        <property type="protein sequence ID" value="GIY76585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W1I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9543" checksum="1439737ECA997160" modified="2024-11-27" version="1">MGHSNYPDSVPFQCVFTAAKESFVKEQHSHNQYGLGPIFFFALSLCRFYLPRQNRPRLSDQANRLIMYGVSSGMFSLAGEGFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W482</accession>
    <name>A0AAV4W482_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_699411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015634">
        <property type="protein sequence ID" value="GIY77477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W482"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17801" checksum="7523ACFDC1629F3A" modified="2024-11-27" version="1">MEGRFASFLVCLVHSDTPWLILEEVPRALTAVGRFKTNSAVEKSHFSLECASTYLIRNPWTASSLIVERLDTSVAKTPDSTERQLGGIHKKARDLITFLRVPHTNVGSFGYSATIRLSESFAFYYGRYAKGNDFVSSTPLPSTSPRAPRELYRLNIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W961</accession>
    <name>A0AAV4W961_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein Shroom3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">shroom3</name>
        <name evidence="2" type="ORF">CEXT_161071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015755">
        <property type="protein sequence ID" value="GIY78419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W961"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1040" mass="115304" checksum="69F4B7450B7BE8A4" modified="2024-11-27" version="1">MECGVLGNNTPAISLVKLNLQAFVDGVVNFIRNHLRSLHVTTSWVTTVSTSIDRTLHRTGELDILLDPYLFLLSCFSSPVLGLSYVVQKKEKADGFCLEWNIRHRPLSFSHQEVTSECVKNHRQLRHSYSQREVSRHTRPTSVESLASSSTDLKKTHAISVESVGAWSGNNPAVTKSTPHLVQGRPQRHSTSSGSLLQSETDEAGANMVMRRFKKGSVYDALASTSGLDFSPIVQLKTYNTRRDDSSTLMPAPQPSEKLREKPAKLQHDKSPVKDKGVTNFSDAANNDSLLNSLNSNISQGIQEPPKKISPISKLDVKEGTCLAAHEKYPSWPVVDPESTSVTYRSHSWTGQTDYPKEKAGFYSRPKKVHQYKISTNQLQPVLERAPDYSSNKTSPEPSDRKQIYRSPQYPTCNSSIGECNGNQQFDFEAFHTPCIPQCFEDKDYRIHSPPERDSCSISPSKSPSEAPSSNSKNSFLNGHEEVRLQAQYSVPLTSMSKQRTPDEKNGSAPNTPFLDRLRLDNALQVPPPPVPMHPVAAPQLQQQQQQLPEPRNDFELSSENGTWMGSMESSSHGRGMPKWQGSYSDLSTLSTQLSNRSSLFDSGHSTMPESGRLSPESSCDSTVPSLLLEGPTRAEVVARHGCHREIVAHSARVQQPERHGSESIVYYATGSSARPNNESKPPSKNTDGAACSSRMIAEGSTAGRLTADESVYRSHVSLTLSPSLSKSNISEREKNTNKCPPSRQDSRKSSNSYSSDDSYSRSRCPTSDDTSGSSSDVSNITCISNFKSSAKPKSLNKTSPTRDLTSKPLDQSMSKYKTGYEPPKSKSMDETTRKFIFPEVDKRQRVSDPELKAIQKQAVLSFYQRMSLAESIKSEPKSLIHSPGADTEPPPPYEALPSNRMKMPTPKLSLPPKNVKQLIPSRPAHPIGLKPELPLPSPESGLQNYHSRSVPNLVMLKGQNLDMPVSRPVFKQPYNGSEFGDAHNQHSRIQKKQGSPLMKEVVLSWDQLPNVLEKKREANERKVSAIYLYQVKGVPFCTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLI2</accession>
    <name>A0AAV4WLI2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Vacuolar-sorting protein SNF8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">snf8</name>
        <name evidence="11" type="ORF">CEXT_525991</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the SNF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016271">
        <property type="protein sequence ID" value="GIY82709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000085">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000397">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017215">
        <property type="entry name" value="ESCRT2_Vps22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY82709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="28027" checksum="E0BFB47F1FF0D126" modified="2024-11-27" version="1">MRRRVGGVGAIQKQQLAQARFKDKGSEIADDQLQQMTKQMETFRSNLQEFAGKYKNKIKKNSQFRQQFQEMCAATGVDPLASSKGFWADMLGVGDFYYELGVQIIEVCLATRHRNGGLMTLDELRKLLIKSRNITAKQEDIGYDDLLRAIDKLKALGEGFRTIACGSTKDFIVQSVPAELNVDHTKVIQRASTAGFITVTILVEEFNWEKMRAEKAIFDLIREGLVWIDEQFESEPSYWFPGLQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WM80</accession>
    <name>A0AAV4WM80_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_469391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016461">
        <property type="protein sequence ID" value="GIY84040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WM80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9670" checksum="E2B8F981ECD2E4FA" modified="2024-11-27" version="1">MLMRHLLFCLSPARSTITGNSVYLTERPAKTEIESWRGFFLVSHVSVVRPDIASSLMSEPYGFLSIYSHCSVSTLPPTAVSPCHKVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WV47</accession>
    <name>A0AAV4WV47_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_510381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016826">
        <property type="protein sequence ID" value="GIY86622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WV47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13592" checksum="0F2E699FFC9AAE8E" modified="2024-11-27" version="1">MNLLWKLSRHCSWGKVRGENNSATGHSRHMSVMDSAILLADKKASDGWHVPLNSPFIVLSPLPRVMNRFLSRFDVFYKWPVQAIDYFRLEHCLSLRRRSSLKVLSWQYEQVDKMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZC5</accession>
    <name>A0AAV4WZC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_494611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016988">
        <property type="protein sequence ID" value="GIY87866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8005" checksum="BCAAA474937488C2" modified="2024-11-27" version="1">MGLSNIPTATDCTRKWKTQLSFQASDREENEWRATVEIETLQNNNICGERAEKEELPAAEEKLVGRVPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X271</accession>
    <name>A0AAV4X271_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_663621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017077">
        <property type="protein sequence ID" value="GIY88584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X271"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8368" checksum="C849D4D8D33DA3F3" modified="2024-11-27" version="1">MAVTVKENGGLRALISALDRWAAEVVTRRNDELFAGSSNVLEVTKLIASMVTCVTKQLNMFSDIGMESIGSGIPSPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3K7</accession>
    <name>A0AAV4X3K7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_165587_1</name>
        <name evidence="2" type="ORF">CEXT_663681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017077">
        <property type="protein sequence ID" value="GIY88590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="31263" checksum="85966816FDB89D45" modified="2024-11-27" version="1">MLNVDTSQRKGSLKIYVWVYCLLVTCGTACFEVTLFNSGMIAQDQHKLRKSEFIPGYLKDHLVAILNSAYAFMILVGNGFFAVLPGYYCFVCCCMKTFFVHFVRKSKILITRQEYRRILKIYKEMNETMIMVDNFMSLPIFVSVVNILVTLFWLGYSFAFMPNVNSATSIFVAMGFIQYFVLLLITLPPAAAVNHAAARARETVLSLPGWFPKRYSIIKMYVRRRFMHKTALTLWKIYRIDKSLLISAIGTLISYGILFGTLGSVQNSNNENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG20</accession>
    <name>A0AAV4XG20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_646151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017651">
        <property type="protein sequence ID" value="GIY93338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10859" checksum="6BD3DB4A368109EB" modified="2024-11-27" version="1">MCGVRLLIWGVEKKGLREGGQPLPKEKRASMNSVAAASKAGGPKPACTQMGFYFTFLCKWVRCSLKEGYTTLESKGLLGRRPGLNCSTDFSSCCCWWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK44</accession>
    <name>A0AAV4XK44_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Collagen</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_426911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000534">
        <property type="protein sequence ID" value="GIY95512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050938">
        <property type="entry name" value="Collagen_Structural_Proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456:SF6">
        <property type="entry name" value="COLLAGEN ALPHA-1(XXIII) CHAIN-LIKE ISOFORM X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456">
        <property type="entry name" value="SI:CH211-266K2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="46864" checksum="FF65DA4179F4C2F7" modified="2024-11-27" version="1">MESKVGYAWTSRRNRDYQVCLDLKVKKGSTGATGVPGMMGQKGEPGLDGIPGAPGPRGLPGPPGPPASATSHRGSIFDLDDTFGGGVYGAPGDGPFTSYLGRPGPQGIPGSPGVPGPRGERGFPGQKGDRGEIGPRGHKGDKVRLFDDPSGYLQREVTEIKGNKGEHGIPGARGIAGIPGHDGIKGNKGEPGVGHTGPRGPPGPPALMSSTTNDIYSESRYGLIRGGIKVTKVRTACRELQVQKEKKGDRGDAGMDGMPGPKGDTGRSRGHQDPQEEKGEKGDRGRRGKRGYPGPPGPPGEPGMIPDLTSFSGGPGHPGQKGEPGEAVKGEKGDRGEPGPPGMGGYEHQDGLEIITEIKGEKGEKGDLGPIGPTGSPGLPGVPGDIGPLGLPGMKDLLDLIVYIDESDEKFIYVPGPPGPPGPVGPLGKTTPGPPGPPGTSRSTRLVNNGLILGQFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL53</accession>
    <name>A0AAV4XL53_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_339541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000402">
        <property type="protein sequence ID" value="GIY94534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="30" mass="3270" checksum="7503B25B9271CD5C" modified="2024-11-27" version="1" fragment="single">KTVKKIGEGSGQRSDEQHKGQSETNNPSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMZ0</accession>
    <name>A0AAV4XMZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_564151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017891">
        <property type="protein sequence ID" value="GIY95295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14316" checksum="4357F4E3BD42F1C7" modified="2024-11-27" version="1">MRFKVSTLIGSDSRRQLNQEIHSLNKSSTTHLIVSAGMSYTGTTSGQCLKRSMIVIQYWQHSDYGNNNFGVSGFEPVVTDNAAIGIGFTSKTLSAISAAFGSVSREIEARIDYPNVGNCCRNNSNRNSSATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNL0</accession>
    <name>A0AAV4XNL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_45751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000696">
        <property type="protein sequence ID" value="GIY96727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7630" checksum="B09C7C383DFCC54B" modified="2024-11-27" version="1">MSSDKYQITLLCGEALFSRKGSPVGFENTSNCGGNSPLSVARDDEIIAILCLVSSIQLRNSCRPISPNLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTE4</accession>
    <name>A0AAV4XTE4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metalloendopeptidase</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_433411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3 4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01018291">
        <property type="protein sequence ID" value="GIY98422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF883">
        <property type="entry name" value="ZINC METALLOPROTEINASE NAS-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043450378" description="Metalloendopeptidase" evidence="5">
        <location>
            <begin position="16"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="6">
        <location>
            <begin position="42"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY98422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="239" mass="27799" checksum="27A44F8D22E4E58D" modified="2024-11-27" version="1">MKIFIVLSLVAIAWGKRTYRNPMENPDLYQGDILGVDPGDRNALPSDSKRWSQGVVYYKMDSSPIYYFQKKILAAMKYIEDRTCIDFIQRNNYERNYIKIFSGDGCYSHWGRTGGVQPVSLGDGCEDVGTIIHELMHAIGFDHEQNRSDRDDYLTIFYDNIDPDFVDQFQKLKPHQNRLINTFDYGSIMLYGDTAFSVDGYKKTMKAKKRGVILLDTYDKMPTASDMYRINWLYDCNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXC2</accession>
    <name>A0AAV4XXC2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_783171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018419">
        <property type="protein sequence ID" value="GIY99392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12775" checksum="07539D7413D92B66" modified="2024-11-27" version="1">MTVRRKSTRQKKKRNALKKKKNNSPCHLIKRQFTLTAEKSTWFLFQKCRNSASEWQRNSVLRAMLKNRDTVLSFVGRTHPVLKPCSSGYICGGYLWSFFSQLPSTPRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y506</accession>
    <name>A0AAV4Y506_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_568981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001398">
        <property type="protein sequence ID" value="GIZ02123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y506"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="241" mass="26643" checksum="6132DB44EA32E4E1" modified="2024-11-27" version="1">MSSKKPRANRIPPLFVSAKGKWSRQVPVSPGSITTTMTTMEMNKDLNSTMAPSITTEAQHCQQLLQAEKEAAHQKTRYDAAIGFVNVANIIADQDLLDKMSTAKMTKIALTKAETEYKAALQRVSDLGLCPLVNCSRHSSAKVKNNNGKIKRTAQADDFHLPTKKQTAKVKFQSVKPVNVALNVNNVFDQLTVDETDDGEQEFSPPEPKLPPIMTQESLQFPSQKAELIADCWFATNAGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB04</accession>
    <name>A0AAV4YB04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Caskin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">Caskin2</name>
        <name evidence="17" type="ORF">CEXT_40461</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001598">
        <property type="protein sequence ID" value="GIZ03400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033635">
        <property type="entry name" value="ANKS1/Caskin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24174">
        <property type="entry name" value="ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24174:SF16">
        <property type="entry name" value="CASKIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 13" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="10" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 14" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="6" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="12" id="KW-1053">Target membrane</keyword>
    <keyword evidence="7" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="132"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="16">
        <location>
            <begin position="225"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="296"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="337"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="426"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="429"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIZ03400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="543" mass="59026" checksum="32794216535CDCF2" modified="2024-11-27" version="1">MCNVPIIQLLLDAGAQVDIKDNKGMRPLHYAAWQGKPEPVAILLQYNASVNEQANKGETPLHLACQHGHVLVTNLLLKYHSNVLIRNKDHKSPLDLACEFGRYEVVNMLLQHQSTRCRSLLTENPQDTADNDRTTCLHLAARNGHVDVIRLLLNAGIDINRSTLRGTALHEAAMHGKLDVVRMLIESGVDVNKPNSYDQTALDIVRSFTTCHAEKEMKHLLKEIINAVQGRAIRDFDDATDPHALPLKEGQQVTVLEQRVDGRWRGIVFHPNYTSSSGYFPASAIQLLDRPVGGLQRTGTLKGGTMKKVPPPVVPELSYRNSGSSFSSGYGSQAAVDRNSCGSLSADEPVSPPPNSPNSDASAYGTLPSPTKLSHFCFPDVQSQYTQVIVHAQPGSGGSTPVDNPPNPLGCPSVCHAMLEDQGIDVCPSPGGSSASGTSSRHSMSSVDSGRASGSDKVVSQKSHSKHIHIETTQHRHSYHSSTSSVSSDDLQIMGNNVAEMMLHGLPVSTCFPFKDSVVLSCRTLRQIDKEIMNFRHSKSVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCM2</accession>
    <name>A0AAV4YCM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_408011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001705">
        <property type="protein sequence ID" value="GIZ04229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11350" checksum="36E8F69BD154A0B1" modified="2024-11-27" version="1">MSGEGEDAVDNDIESESQQTNSSKARPYLPRAATKPIPEISETDVTHKAHKRDSSPVDCAVKQAVPLKPATTSSGLKTRRPWELWSVEDKNAFLKPSVNMEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCS1</accession>
    <name>A0AAV4YCS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">spop_16</name>
        <name evidence="1" type="ORF">CEXT_200181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001673">
        <property type="protein sequence ID" value="GIZ03967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="304" mass="35283" checksum="3CBCEEB2C6AAD94E" modified="2024-11-27" version="1">MASQVNDFTVTWRIENYHLRFHRPDYYLDSVEYLMDTMEQTKWTLRLDPCHSKDKASLCFRRSREDDGPDALSLDYEFSFHPIRWVMDTSGKTIQNYIQERLLQRTSGNASRKIRERKEEKSLSSVVLTVRCRIWKSDGSATETGRCFIRTRLKEDNTAFLAFVEKFSTAVTSRSTAVLKIRSASLAKPSMSLNLSLKEGVGCQDSILLGIVPSEPEAFFYCKCQLFVVEATGLKTECGVYEKFPIDFETIIGWKIQLPLTKAHLMQRRTAFLPDDVLTFQCEFTFSTGIEFERVEKTEFERVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD55</accession>
    <name>A0AAV4YD55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_26001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001718">
        <property type="protein sequence ID" value="GIZ04316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17864" checksum="EC80755D07AD500F" modified="2024-11-27" version="1">MGFYWLTRHRVKYICKMRSRTAWRVMTAARVCNTKAATADVLIGWRSNDCTFSLHDQMMSSLPDDIFEDTPRLAYVNLKGNRLTTLNQKAFSKRRVFYDLRDNFINCNCNIKWVTTHGNSYSKNMLASCAEPTTFRLQQLDDLEEDDFDYCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDS0</accession>
    <name>A0AAV4YDS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_88891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019196">
        <property type="protein sequence ID" value="GIZ05059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15854" checksum="B4FC79D5168D925A" modified="2024-11-27" version="1">MIAYREKNRNVDLSMLKEQIAASKQEGSCVFTATSMQIVAFENGLLAKVWRETIRRAVIIAGPLISSERLKRKGSKNIGVGRTHPRSVFNVPENGVFSLARSLVLSLNGDPFFFFHPLKPFSKKTKEKKISHRWHLMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE06</accession>
    <name>A0AAV4YE06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ZP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_307481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019223">
        <property type="protein sequence ID" value="GIZ05149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4100">
        <property type="entry name" value="Zona pellucida, ZP-C domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057475">
        <property type="entry name" value="CUT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042235">
        <property type="entry name" value="ZP-C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560">
        <property type="entry name" value="CYPHER, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560:SF9">
        <property type="entry name" value="ZP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25301">
        <property type="entry name" value="CUT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00241">
        <property type="entry name" value="ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="ZP" evidence="3">
        <location>
            <begin position="105"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ05149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="507" mass="57313" checksum="F3BD7E5BA1F02D7A" modified="2024-11-27" version="1">MKPSLSDLLSRSAGRVDDMFPKFIRRRKEEKIPFSASIKQRTTYLDQKPRPTQTQNRFFSIRSKEKEKMRSYPSYLVHPSKTVPGQQFLTDEEEDEEFTPVVNHRCERGQMIIEVTTQQPFRGIIHPRDYRSGPCVAQGRGGRTTTLTLDINADKDDPRYCGVQFRKPNSGDVTIALAVRVHPTLELSEDKYFFLTCGKAGFRNARNETSRVTLNFYHDGKKVQELIYNQEYELRAQMTKPDDIHKLKVRSCLSFSPNTTEVPLIDSNGCPLNQFLTAFHYNETSHSANAHLSSIFKFPDTNKIYVQCDIVLCRGPCEQAPCRKPSEPLPRALPRTRNGTEDGQLMASTSAYILEPGDPILAESLESCTEWRFPWLIGLCICLAILLLVMLIVNIFLCSSLTCTCTKTEVVDKEPSEMDDYDPYRVGWVSGSHYGSRSSLHKPGYLSGGSTLNSTARSVSNASDHYAIVHSRPGSRYSQHSSKEPLHKSSGGSILSNGHHNHYNSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YEX7</accession>
    <name>A0AAV4YEX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_9801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019166">
        <property type="protein sequence ID" value="GIZ04919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YEX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16564" checksum="6BB1D850723C21B4" modified="2024-11-27" version="1">MLSYRAAIYMEKSLEAIFDEELWSLRIKREENNIQMNQLILQTASPSLPWRVVDIVGGRGVTVSPSSQRAQEAPFLPARQRIFVLSCGAAERRNPTGCPGGKQHFVRRQHKRGQPHVSPPPSRSLSASLSNLWLPPSQVCMAFTNISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YEZ4</accession>
    <name>A0AAV4YEZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_214341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001761">
        <property type="protein sequence ID" value="GIZ04596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YEZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9450" checksum="446EA3E3647782FE" modified="2024-11-27" version="1">MIEAPEPKLPPIMVRYTDNLKDQIAEISNQFEDDVRIKFAGEQLKIFPQTLIYTERSLNILLMGKSNSTSSPLRINARLKRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6R5</accession>
    <name>A0AAV4M6R5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Fasn_13</name>
        <name evidence="1" type="ORF">CEXT_56031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001896">
        <property type="protein sequence ID" value="GIX67729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6R5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="20688" checksum="B1441B8FA7DE127A" modified="2024-11-27" version="1">MDISGHFEITEGKSVVAAGEVRLLENPVFNEISLQINEDSNALSSKIIYDELRIVGFEVGPAFQGLSKVDVEGTSGLVLWQDKWIPFLESLLLFFGVTTKDNEICLMSEVASLKIDPHLLRRAVSENVSSLTLPVNYKKHIRKCCSIGIELSNAHLDHVVHQEITDEPVLSNTSLSSMKSVTLHLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7W0</accession>
    <name>A0AAV4M7W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_642771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001975">
        <property type="protein sequence ID" value="GIX68542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16511" checksum="6F22205D8220C2EC" modified="2024-11-27" version="1">MKNKTLHRTWHRKPRLVGESFQNIYAMCTTVQKNMGFLHDGAPSQCVTISMLNILLGGLNTLDLLLRLHKSQILISGFLLITPQSTLSEILQKLIAHIAIAVADITSRSSIFKFVQQSFLGRCRQCNICDCRNPCNHFSLSRFWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8A9</accession>
    <name>A0AAV4M8A9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001989">
        <property type="protein sequence ID" value="GIX68692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8A9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7991" checksum="85CE26FCC5832562" modified="2024-11-27" version="1">MLDYRYFTRIFGLSGLSDPVICRGIHLHLNYNHTVKLKCDINCPWHLCENIHSCLSYAWLCETLKSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBX0</accession>
    <name>A0AAV4MBX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_5441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019579">
        <property type="protein sequence ID" value="GIX69365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16670" checksum="5485554EE1DABC31" modified="2024-11-27" version="1">MRAPGAPDCARRLDIAFPFLGRKKKKHEFLGMDAKESKMDVLNEKADEDFRDILLNELYPKDDTRGLFVPSDTSGKDIPTYRVIAPALEMEDVGSNGKPYDANTENLKNGSAFLWRRNSVPGDFEESLCAPGARRGRTRDTASSFLGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD35</accession>
    <name>A0AAV4MD35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_15161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019667">
        <property type="protein sequence ID" value="GIX70329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10161" checksum="7C6192E9CD3B8B80" modified="2024-11-27" version="1">MLLPELTANRCQGPKHRVDETEVTLICNNTALPPPGSWYIYIDVMVQKLWLKLLRDASTLSATWLQLNCCINKYMIDILFVWFCTTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDC2</accession>
    <name>A0AAV4MDC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger protein 471</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ZNF471_1</name>
        <name evidence="9" type="ORF">CEXT_653811</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019664">
        <property type="protein sequence ID" value="GIX70285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000557">
        <property type="entry name" value="zinc finger and SCAN domain-containing protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001498">
        <property type="entry name" value="Zinc finger protein 404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX70285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="185" mass="21592" checksum="1B2FBB4C34736999" modified="2024-11-27" version="1">MNNVIFQGLLLLQNDHPPTKHAVSVNDFHRCTMCNYSTPHLRNMPKHVRTHTGERPYELPVLLSVSNRFLSCSIKDENIKSAVVPFSSVYRTQREPIFELNSSLRHLIGYNLLDETPLPNICFVDKPFVCHHCGKRFRFKGDMQRHTRIHTGEKPFKCNICMKSFRQSSHLNQHKIVHYRAAIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFY7</accession>
    <name>A0AAV4MFY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Forkhead box protein K1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FOXK1</name>
        <name evidence="6" type="ORF">CEXT_406441</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002132">
        <property type="protein sequence ID" value="GIX70361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22688">
        <property type="entry name" value="FHA_FOXK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF7">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="55"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX70361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13245" checksum="F7CBB9A0A5B779AE" modified="2024-11-27" version="1">MSGAATNDNDAWALLSLKSAPSSPTKIVWSPEPNAAAIARLEGREFEYMIRQNRISIGRNSSRGEVDVNMGHSSFISRRHLEIYFESPCFFMICNGKNGVFVDGVFQRRGAPPLQLPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGV6</accession>
    <name>A0AAV4MGV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein transport protein Sec61 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEC61B</name>
        <name evidence="12" type="ORF">CEXT_464661</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019771">
        <property type="protein sequence ID" value="GIX71623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX71623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="9862" checksum="D7810AE6C524E4E4" modified="2024-11-27" version="1">MPAPSSATSVGAGSRSPKSMAPRAGSGSTVKQRKTGGTSASRTTRAAGSNSVGMWRFYTDDSPGIKVGPVPVLVMSLLFIASVFMLHIWGKYTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MH95</accession>
    <name>A0AAV4MH95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_185951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019746">
        <property type="protein sequence ID" value="GIX71344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MH95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13122" checksum="4F911415ABD8E2B8" modified="2024-11-27" version="1">MLIPFLPPPPTHASTGQSSCVISRTPLQWANLVLDAQAIPDSQRAGGLVCELVTLFIAGSFYTMPFRRSKCFEKQRRPSEVALGQSELKIKYSEAANVTNQRTVRFALIYPERLAGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQN2</accession>
    <name>A0AAV4MQN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_269521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020090">
        <property type="protein sequence ID" value="GIX74710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043528644" evidence="1">
        <location>
            <begin position="26"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15371" checksum="9787CF300E3568F3" modified="2024-11-27" version="1">MTTHLRHPPLLVEALCLFILDPWLLFRISPTPSPFLNGQKCSYYLMLLNAPYLLLSRPGELCGRRTHFEQPERSQNGEIFEFSEFGIMEEGIFAEFPESWGFRNEYERRIREHVGLGGRHTEDSPPTCLGASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MV05</accession>
    <name>A0AAV4MV05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_591211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020186">
        <property type="protein sequence ID" value="GIX75633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MV05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8130" checksum="3F0DB9A4A35D0208" modified="2024-11-27" version="1">MSPQIGYQLSEINPGKRANVVLSNKLNAKIEFLSGLGPSKGCSDDQCLWTSTSPPPFFTVEWPVSIENGMMAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX33</accession>
    <name>A0AAV4MX33_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Jarid2</name>
        <name evidence="4" type="ORF">CEXT_305271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002712">
        <property type="protein sequence ID" value="GIX77035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16870">
        <property type="entry name" value="ARID_JARD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF113">
        <property type="entry name" value="PROTEIN JUMONJI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="3">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX77035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="244" mass="28361" checksum="E92CF5C9836C6FBD" modified="2024-11-27" version="1" fragment="single">MGGIELDIAKFYHTVQQFGGLQQVIEKKKWQKIADAMRVPKSAQDRVTKLYDAYCKYLVSYDLLPKEEKQKIIEEVKADHEKHFKLRFSPSESEKEDDDVDDEENYDCVTKGRSMSLSNFFRIARNTMNMWFKNVPTPEEVEHEFWKIVTERQHHVVVHAGNIDSSVTQSGFPTNRKTSFAKHPWNLKVLTNNGRSVLKCMGPLSGITIPTLHVGMLYTTGCWYRDPHSFPWIEYLHTGAKTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYH1</accession>
    <name>A0AAV4MYH1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ras association domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_109348_1</name>
        <name evidence="3" type="ORF">CEXT_167861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002756">
        <property type="protein sequence ID" value="GIX77443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048945">
        <property type="entry name" value="RASSF8/10_RA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21712">
        <property type="entry name" value="RASSF8-10_RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras association" evidence="2">
        <location>
            <begin position="28"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX77443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13884" checksum="8DAF45CF1938C776" modified="2024-11-27" version="1">MSPLTFPRDDTGDSGRSRGQWQVGGRSITPDTKCQDVIECCREPSDEMCALVQTTGLIEQVVPEDTCMMDVLNRWETIGRLSPFIFSIAIPSKTSEIWVSTFSPSFSTFRVFFCICSFSLPVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N526</accession>
    <name>A0AAV4N526_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_177011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002976">
        <property type="protein sequence ID" value="GIX79809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N526"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="15394" checksum="0984304F94D81CE4" modified="2024-11-27" version="1">MSPVSETSYIVSPSFRFRFSCNFISTKYITWQCGSLSNRPRDPGAEDVSSGDLLVCATEASPPARITWLLDGNILKYGGGRTHRCSVALCAVGSLWSGSSRSPGVLQTSEDGPRETGPWKTSKLLLNSQNSLDVSISEKFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCG0</accession>
    <name>A0AAV4NCG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acidic mammalian chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Chia</name>
        <name evidence="7" type="ORF">CEXT_607661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003240">
        <property type="protein sequence ID" value="GIX82465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043371720" evidence="5">
        <location>
            <begin position="21"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="11"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX82465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="248" mass="28785" checksum="D141AF05D4921196" modified="2024-11-27" version="1">MGTLSVLILCLSIFCITVQSNRLTSPKNTNSKKIVCYFTNWAQYRPNEGKYVPEDIEPTLPKTERKECTKDWWKSRTRTKMPKFLLAIGGWSFGTQRFKEMASNRYNRQLFVFSAIRYLRDRNFDGLDLDWEFPRGGDDKKNFVLVLKELREAFEEEAKDKKMPRLLLTIAVSAGSETIRSGYDVPAVAAYCDFINIMSYDFHGKWESQTGHNSPLYALSTESQWRKQLCMVKIFILSIHLELSSLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ND57</accession>
    <name>A0AAV4ND57_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_545591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003259">
        <property type="protein sequence ID" value="GIX82682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ND57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX82682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22667" checksum="53F5EE7654AFD65E" modified="2024-11-27" version="1">MTSHFKETPPFATEFAKFSSAVQFEFENVKDFSIRVQGLSQKCLESDSENEKVSEGFKEKLLLSKFISGLKGNIRTQVLIADPSSFAEAVDFALRVERSFEVASPNVNVISQTDSNAVEGVKEGFTKTLDLVLKQLEHLNTRIDELDKQRDIPENNYTNQPPSQRRDRKPLKCFYCGRLGHIASECQRKKERLSAGWSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE15</accession>
    <name>A0AAV4NE15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_160021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003274">
        <property type="protein sequence ID" value="GIX82936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7849" checksum="CCA26D9F8A500895" modified="2024-11-27" version="1">MGSLRWWANQNSSCWREGRVMERMGCGWVERRQNISPPPSDFSIFVLCSRYYRGLDGDHHGIQGRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEN7</accession>
    <name>A0AAV4NEN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Neuronal pentraxin receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Nptxr</name>
        <name evidence="13" type="ORF">CEXT_150951</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020812">
        <property type="protein sequence ID" value="GIX82770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000122">
        <property type="entry name" value="Protein crumbs homolog 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000045">
        <property type="entry name" value="Slit guidance ligand 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.10:FF:000018">
        <property type="entry name" value="Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000240">
        <property type="entry name" value="Vitamin K-dependent protein S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12916">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12916:SF4">
        <property type="entry name" value="UNINFLATABLE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12661">
        <property type="entry name" value="hEGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00093">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00010">
        <property type="entry name" value="EGFBLOOD"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00895">
        <property type="entry name" value="PENTAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00214">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00216">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01208">
        <property type="entry name" value="VWFC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50184">
        <property type="entry name" value="VWFC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="227"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="266"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="304"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="342"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="380"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="418"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="12">
        <location>
            <begin position="459"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="692"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="10">
        <location>
            <begin position="773"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="VWFD" evidence="11">
        <location>
            <begin position="835"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="718"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX82770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1036" mass="115224" checksum="0FB85979B31952C9" modified="2024-11-27" version="1">MWTSPAEITTQKGSGRSKCSFVNTNEASVNASQPFLKEIETLASQNVKEVYSVDSIKAPKISYQIDLICSLGQIRNDNSCIDCPAGTYKDDISDACVDCPHATYQDTENSFSCLPCPQAPCQPGTYSRTTFEPCHVCPLHTYQEWELGKDCLKCPNGLFTWRVGSNSSKDCVSPCQPGSFSDTGLEPCTLCDFGFYQNSSQQNSCEECPVGTSTRNKGSIAVEKCQKVDACEELQPCSNGSTCMSHGNSYLCVCPYGSLGERCEQTLNFCESDSCTNGGTCVSVLGDYKCLCPVGYSGLNCEINVDDCKNDSCNNNGECIDLINGFSCVCDAGYTGERCEVNIYECASDPCRNGGTCFDKVNGYKCCCPAGFVGENCALELDPCEEVTCQNGGTCIPDGTGYVCDCEPQFKGIYCEEKIDQCLNYTCYNDGACVNGFDHPYCKCPLGYNGTRCETELIPEYSLNFKNPTTSNFVKLENKEFLYSITVAFFMRTELTDPEKRPTPVSYSYYDKEKEELVDNALTVYDVNKIVLYLHGETLHTGYIANGDANWHHYAVTWEKDRGKWSFYVDGKSISSGLHVGERRYFWPGFFILGQEQDSLGGTFSMSEAFAGDITEFNVWNFALSEEEIKSISSTCGIVGNVIPWVIASVHIHGSVTISSDVSICKGIGTCSAKDCYCFYSTENTSEICKHSVQSCNPNPCSYSQECVATDSRHHCSCDVGYEGKLCEYDLNECLENNGGCSHVCVNTPGYYECQCPEGMILSKDGFNCQDINFCKVGEQIFLDGENWISDCQKCICEQGNVQCFEMQCVDTTCYPGELWVQLPGNCCPKCVSYAFCSISTNNSLLTFDFSTVEVSNICDFTLIEDCVNGQFSVRMESKHNFSSHGNLVIHQDCQQLRVSEDGEVTFNNDSMVLPFKNEDFHIKLNNESIDIWMKSGLNIQWISEEILVAVPVERANRLCGLCGNYQDHHMRNTDYNFTESKTSEKQVCIIHREETQEKIPVSKSNHLSSFTLTNLFQCVLMFLTYFLMCDIIHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKT5</accession>
    <name>A0AAV4NKT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_703501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003512">
        <property type="protein sequence ID" value="GIX85419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15760" checksum="EB18410CAED23544" modified="2024-11-27" version="1">MLRRDNHSAKSQDDDIRSHKELIEALFEALPHIHFKQLFRYVDGVGTFMCDETTHIWDKISNGKIQSTLSNLVESNVSNLSPRETKLVGQFNYLTYLRQCFQAFMEDPEFIKKLDNNTHLFALQNGVLDSFHQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2Z1</accession>
    <name>A0AAV4P2Z1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_492431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003925">
        <property type="protein sequence ID" value="GIX90269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2Z1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19496" checksum="7F9D3200F721E009" modified="2024-11-27" version="1">MQKSLCCVEPSDKKYYLSDQAGHSNIHPAKTSPVRYQYWDPKEQTVTHRKDIAMLLSPLINIGGLYRSLKPPEQFANVLWTMSRMLFSALCEFDKILVPSDRNVIYDQRGHSNIHLAKTLLVRYQYWDPKEQTVTHAKDIAILLSLLINIGELYYRSLKPLEQFANVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3H3</accession>
    <name>A0AAV4P3H3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ZDHHC5</name>
        <name evidence="10" type="ORF">CEXT_273052</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:36684"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="BPLR01003995">
        <property type="protein sequence ID" value="GIX91103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3H3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12349">
        <property type="entry name" value="ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12349:SF2">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="98"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="353"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX91103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="636" mass="70986" checksum="F889567AB5518457" modified="2024-11-27" version="1">MSKCKSITKFFPITCAWTLLIATTSLFFVFPCPYLTVSYHIAIPICQAIITFFVVVNFSLATFMDPGIIPKATPDEDKEDDFHAPLYKNIKINGITVRMKWCVTCQFYRPPRCSHCSVCNGCIETFDHHCPWINNCIGRRNYRFFFLFLVFLCVHMISIFSYCTLYTLEHRDQLQHRDTIVTLVIIVIIALLFIPILGLTGFHVVLVSRGRTTNEQVTGKFQGGYNPFSRGCWRNVCFTLCGPLYPSHKVRRKPRKQLSVAAPTVSAHMGENQVKVYMDNSNSARSTSSAYNKMSQGAGDLSDVDVILDSYDHNQSQSQDCEPSPPIPRHGSKTNFFSPSECSRSAYILPQSKPWSPYGGAGPPTPRAPRASIPMDERTVQVMPRSPEGMPPWAIVNSPRSTRTPPRSLTSPVVGSDGSRNRQQSPSRRSSPGSPASLTPGQSPVAVKRHQSGSRRGPPTPHYYGYHGTGRSGRSSARNISPNRKFASESELARAAADKANGNYEARANQTADNIQELADSGRPWEERARRLQHVPDIPMVHTGCPPPSRRTTASPQSRRAGGHKTPPLEASPVKPYPKRPVSIVKALEMTENYDKGGSKVDPHSRQYLQQNKSISSNIEQDDRKSLYEMNYEISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3X3</accession>
    <name>A0AAV4P3X3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_766201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021461">
        <property type="protein sequence ID" value="GIX89907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3X3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10562" checksum="741B1F8F53BDB949" modified="2024-11-27" version="1">MIKIFRTFMEAKVLILIVQIYFKKVRKSVSLSLTRILSDPGPLAVWSLGHFTLPFFFFFFIIKMVLNSLLRWSSLSFGSILLSRYLPHTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P827</accession>
    <name>A0AAV4P827_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Fcan01_15639</name>
        <name evidence="1" type="ORF">CEXT_302141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004243">
        <property type="protein sequence ID" value="GIX93397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P827"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="31826" checksum="E4133B7E79438EF9" modified="2024-11-27" version="1">MEDYLKLVHMELIPENEIDVPANSSFYLPHHPVPNKSGDKFRVVFDGSAKSSTGVSLNDKLMVGPQLQADLTTILIRFRMHKIAMTADIEKMYRQIRLKDSNFQRIVWRDSPFKPIQDFRLTRIAYGTASAPYLAVKCLQQLAIQEEQNFPLASKAALKDFYVDDLMSGANSTTEALDLQAQLIQMLSSAGLVLRKWASNCNELTNLIQEDLRLPNASLSIDDGTVKTLVLGMTIMSESIEETEGRPAIVVESPLSPSFTEVSNMDIEDNVNQIVFIPTELTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCC9</accession>
    <name>A0AAV4PCC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_314031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004351">
        <property type="protein sequence ID" value="GIX94245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15000" checksum="AF117DD56E48C5A3" modified="2024-11-27" version="1">MEMTRGHYDSYASLAESAGHVTRMHVSTFPWSWGKKCGAPTHAREGLLWSQNCLSDINFSFVIKPDYVVTSSLFDEWTTPSRRLRLLRRQEKERGGRMSGRDGRSGDGVRSQRGRVRAWPLLIIVIKGLPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGG8</accession>
    <name>A0AAV4PGG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_454971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004556">
        <property type="protein sequence ID" value="GIX95734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="350" mass="39991" checksum="B227D43899031919" modified="2024-11-27" version="1">MKTNAILSFISLFHWKNRWSPLIYLSVLLSVFALNVQCNVYQPESSEAVSNPHSFPNGQTSYGPVRDSNGNQHLKQTTFNDAQRHQTGTFTQRDTSQNMNSNYNPRGSYEPFLQTQHSDINNREKANISSVRNVQNHQGDSSQGAVRYFPASSLQSPNNYLQNSQRNEQLQDSHDSNHKISQNRNVAFTQQGHLSSDKNKYDSKPNAAGINSQKVKKVPIVLITIQKGQRASTNKKDNVNTNVKNQNQDGNIFKYNQNYSTYNSEQTINYDSPVQINNPQSKHPPPTHSKLLQPVQKGFQNIHKISLTILLRIIMQSNLVFLKREYLIPKHLIGLLSTEVKFKQQIHFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHY6</accession>
    <name>A0AAV4PHY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_756881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004739">
        <property type="protein sequence ID" value="GIX97112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13512" checksum="128FBB36F2C2CE19" modified="2024-11-27" version="1" fragment="single">SAESISPWRELKVPSGENNGILHETFSVYGDVHFKVLRVVYGEVLYGLRYCQEFCHIHNGVSADSEGVVVSFDVIVVHHERACNFIVHFGPVGEDQYPLGDHFCRESMGLRNNSTEEESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKH1</accession>
    <name>A0AAV4PKH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_174774_1</name>
        <name evidence="2" type="ORF">CEXT_221551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004639">
        <property type="protein sequence ID" value="GIX96374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="466" mass="54209" checksum="50E1DEE4B5B0BCE4" modified="2024-11-27" version="1">MRKRNKKTRVKSKKMYQFLQKPQKHGNLVKQMENIVLYILEIITKIKKDWSRHSSEPNSNTDKINDDDEVYLSFDTHDFLKLNEKFGTNPKTVFMKNDLTDWSERVPVPQTEQPNIVLLENRTLWELLDSEENESQQSTSKLSTDENEDNQGRITFPSETEYKENHPLKSGKRGQEISELELNSSSKEKSKGCEHTVEQPTSQSPLEKTYLNLNESDLHILSTPESDKTNLDPSFMPTPILRITRSKLEVDDQEKKRGKSAGNIPNTVAIKKSRKQRPSKWFRRNNVPTESLDGESLSLLDSQLIDEKDIPDHTAVSLNIRSMPTEPKQVEKVDTNLVVHTHEATEKLQLRMLDSRHIYNEMVGEYTGRNVGNLDETWRNIGVPVTGRSWLRSYLTTQVIRRYQKQWNLENPPVDDEIKELAIPVLKPHECSYGLGSYFSHRSLFGSVRTWYFSKKLREYQKTMQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PN85</accession>
    <name>A0AAV4PN85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adult-specific rigid cuticular protein 15.7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_500361</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004764">
        <property type="protein sequence ID" value="GIX97319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PN85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043853727" evidence="4">
        <location>
            <begin position="18"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX97319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="20839" checksum="B624DE4A1544AF81" modified="2024-11-27" version="1">MIAKVAILFAVLAAVHANVLLGGHGHLVNTGVSTSARTQDVSRCFRQQCLRLPPIKDGLGATNSRSEVGDGYGNRKGSYTITDIDGRARRVDYVADGHGFRASVKTNEPGTAASAPAAALINSPYAGPVAPVVNHVAPAASYAAPLAVAAPVAYGGVIGHGAGLGYGAGLGYGAGLGLGYGAGLGLGYGAGLGHGGALGLGYGLGLGKGLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW59</accession>
    <name>A0AAV4PW59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_238711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005269">
        <property type="protein sequence ID" value="GIY01141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13825" checksum="89A605338A97FCA6" modified="2024-11-27" version="1">MKRQPPREEQQQQQKVNEVQSLVARCCNLLNLRHQHQVWKKTLQHYFKPSVKWKLMKTPTEITKVKNKLERTFRKKLKRSKEMIMKKKINQKTALQKKRKENEEKKKQMKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0I4</accession>
    <name>A0AAV4Q0I4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_532141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005357">
        <property type="protein sequence ID" value="GIY01697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0I4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10398" checksum="6254750CF107889E" modified="2024-11-27" version="1">MSDPFTGLKICYWNANGIYSKLTDFKNFVHNNNPDVILLQETMLKPTQTIFISNYIFFRKDGPQNPVSGGTAILIKKNTSHHEVPTPSLKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8D8</accession>
    <name>A0AAV4Q8D8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_641971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005701">
        <property type="protein sequence ID" value="GIY04346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8D8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11274" checksum="BE48AF479EC6601C" modified="2024-11-27" version="1">MNTRGEITRQLFMQWIHPAPPNVRRNTLSWTVRKTGNRVGKENQKKTLLNFLSPRRSAIVKWLTFSAFTPEIKGLQQSMPFLEKNVQKPDIGLDKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QB66</accession>
    <name>A0AAV4QB66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_706381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005983">
        <property type="protein sequence ID" value="GIY06634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QB66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7808" checksum="AE12006C5B186F0A" modified="2024-11-27" version="1">MAFRRSSLQGLPFIAGVPEGWLGGALSLTGRNLYGNAAVSDGQKDDRGGIFVSGHLLQGRGKKNCFRRTIWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMG8</accession>
    <name>A0AAV4QMG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta,beta-carotene 15,15'-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BCO1</name>
        <name evidence="6" type="ORF">CEXT_196801</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006477">
        <property type="protein sequence ID" value="GIY10126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003834">
        <property type="term" value="F:beta-carotene 15,15'-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042574">
        <property type="term" value="P:retinal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY10126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12222" checksum="1DC5551717EC03B8" modified="2024-11-27" version="1">MEALKASAVLPYLRSCKKESEKAIDGELQGEIPKWLKGSLIRIGSGLLEVGPDRYNHVFDGLALMHKFCFEDGRVTYRNRFLRSDSYKKNMKANRIVVTEIHATPGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QR62</accession>
    <name>A0AAV4QR62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_162681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006630">
        <property type="protein sequence ID" value="GIY11294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QR62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10839" checksum="E0CC9C16526804E9" modified="2024-11-27" version="1">MKKKHQLIVWPPNLVREWIVIYARNFLSLKRCATVGARLCIGWSEKQRAASLPTHQVANDSPPRNALRSPFATGNSRFPTQHACSIHTTFVYTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6X8</accession>
    <name>A0AAV4R6X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_577541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007511">
        <property type="protein sequence ID" value="GIY17449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11098" checksum="C98DCA17382DBD8F" modified="2024-11-27" version="1">MLPFSPVTSKKTNAIIPDPANLSIRHTHLRTNDIGDSISHILWTTRLRMGCLLNQCPTSTPLTILTHGDHMGQMLPQSEVGRHLLTFVLGGGDSFTTGRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RD03</accession>
    <name>A0AAV4RD03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_95831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007568">
        <property type="protein sequence ID" value="GIY17958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RD03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13500" checksum="76A138C579961103" modified="2024-11-27" version="1">MRQVVVRGDFLLGFFFPVRLGTVRKRGCDFLLGFFLLAWGLYEKEVGKSSVNRSGYGVYQTRKYPAILKKLSLKSTRFPEQKQKFDELQQSAGGEILKILVTMGEEKKKDRRMEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RD37</accession>
    <name>A0AAV4RD37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_604511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007802">
        <property type="protein sequence ID" value="GIY19888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RD37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10861" checksum="D5D567A6DCE4D858" modified="2024-11-27" version="1">MHLAEHCFKNNLKGNHSPLKRITYVSQFMTPLPRRWSPTSLILISYGLEAPHTRQLALEIGCLPRRWNRTTLMLICYGFEARTPDHWCSSGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMF9</accession>
    <name>A0AAV4RMF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_643381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008025">
        <property type="protein sequence ID" value="GIY21491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11941" checksum="FFFE36164F5BB35D" modified="2024-11-27" version="1" fragment="single">RFRRPVTLSPMFIRPKSGMRPAVVALKEAAKWLSQTQARSWRWHEMLQGLESVPDAKMTAYSLTTICLWGHGYLEDRQTRLTFIAQNSLHYEKCSRQLSIAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRM9</accession>
    <name>A0AAV4RRM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_37441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008419">
        <property type="protein sequence ID" value="GIY24553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9250" checksum="498D5EB9ACEACFCC" modified="2024-11-27" version="1">MFPKGVIEIRSFNSFPLTHKAAILDVLTKVPNTIQRDLSDSHTFPRKLSTVSSRNWARAQTAEMPGIRKNQGLLWRLQPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTC3</accession>
    <name>A0AAV4RTC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_248751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008434">
        <property type="protein sequence ID" value="GIY24637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9311" checksum="4FE4E674F71F6949" modified="2024-11-27" version="1">MNENSIVITFSKAEEEYRLHRRDPKVSYKIGYSPHSVKLCRLGQISTRNRDGSNCKTSLQTPTKERFKYIEASFLLAEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVE2</accession>
    <name>A0AAV4RVE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008490">
        <property type="protein sequence ID" value="GIY25094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8944" checksum="63386D41045F534D" modified="2024-11-27" version="1">MIQNDRMFELAEIRIHPSSIQNILPFMLWGSGKFIPLAITTSFLKSAFPDEFVIDDAKDARLQLRGDDERIARSSSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWJ5</accession>
    <name>A0AAV4RWJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EF-hand calcium-binding domain-containing protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Efcab14</name>
        <name evidence="3" type="ORF">CEXT_273321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008629">
        <property type="protein sequence ID" value="GIY26115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042352">
        <property type="entry name" value="EFCAB14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15717:SF2">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15717">
        <property type="entry name" value="PROTEIN KIAA0494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY26115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="290" mass="32070" checksum="4880613AB5EFF3B4" modified="2024-11-27" version="1">MKKRKELDALVSNGKIGSRINCNKKASGSCSAHELLRHDTDSSDIEDFSILQPRRKGRKKHGSRFCITSVCLSLCQFILVTTSCLVSGALIWLHIGLREDIDLLRAHLQKVEAGNRNTPEALHLIHSSLKTLDSNVTMLYIDAKKTIADIENITSEVKLLKETATSLRASIASAPAIQQLPKDMHSLSESVANFGSKLNALESNIKELKDQQSNIQTSWQNLSGELDTVKISVQDLTNSSDFQAKSSVNTSAKDLKLQNAIQETNQHVENLQGTLHFLKLLDVHHQQIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RXA5</accession>
    <name>A0AAV4RXA5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_501311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008570">
        <property type="protein sequence ID" value="GIY25739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RXA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035539">
        <property type="term" value="F:8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16099">
        <property type="entry name" value="8-OXO-DGTP DIPHOSPHATES NUDT15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16099:SF5">
        <property type="entry name" value="NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10378" checksum="838E4C78FA0768CC" modified="2024-11-27" version="1">MSADSLEIIKRPGVGVAALVVNNQYPNSVILGKRKGSVGERLYQLPGGHLKFGTCQRTFEPRHLSRCRYEMACFACNVSNGDHSDPNSAHEIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S279</accession>
    <name>A0AAV4S279_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein toll</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Tl_0</name>
        <name evidence="6" type="ORF">CEXT_30631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008767">
        <property type="protein sequence ID" value="GIY27069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S279"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365:SF541">
        <property type="entry name" value="PROTEIN TOLL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365">
        <property type="entry name" value="TOLL-LIKE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY27069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="292" mass="33893" checksum="59D49FD96EC581FE" modified="2024-11-27" version="1">MPWDACYINYYIQVQDANITKCGPDKKKSAVFAEKALWSLTDVDLCPENIVLYVTIAVLVPDAREGVALLPRVTWVKEKDIDKDKEFDAFISFSHKDQDLVIPELIDRIRSEAVYPLQALSAGRTHPTQHHAGHSGFQEDCPRAFQVRILIPKHTLRMRCMMIHKPFFSRSSFLESEWCMFEFRVAHIEGLKNHLNRIIIIKMDDLPKDADLPEEIQVYLKSTRYLKWGTSTSGTPYSTPFPDLSTLPNHLIQNKSLKFPTFIVNLIPLLEEGNSCYLHHSHFYFKKHFPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SC41</accession>
    <name>A0AAV4SC41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_83061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009393">
        <property type="protein sequence ID" value="GIY31564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SC41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15395" checksum="E064C4F1D6E4C98C" modified="2024-11-27" version="1">MLINGAVGKGLYGMVPLSGVMPLRVSDCDRIMVYCRRESDESLASQITRTELPVTDSHEGDHLQGKSEWSMTCMGITYGHLWESTEKEDLMRNLDFTMEATDRWLGQKSTEFPINPNFPTPDIRFLPSFRTGNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE19</accession>
    <name>A0AAV4SE19_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrator complex subunit 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Ints12</name>
        <name evidence="11" type="ORF">CEXT_461122</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Integrator subunit 12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009525">
        <property type="protein sequence ID" value="GIY32578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160232">
        <property type="term" value="C:INTAC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160240">
        <property type="term" value="P:RNA polymerase II transcription initiation surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15501">
        <property type="entry name" value="PHD_Int12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000101">
        <property type="entry name" value="Integrator complex subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039054">
        <property type="entry name" value="Int12_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051776">
        <property type="entry name" value="Integrator_subunit_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13415:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13415">
        <property type="entry name" value="NUCLEAR FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="220"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="115"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="353"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="439"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="439"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY32578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="488" mass="52536" checksum="B32AC3570E5BD964" modified="2024-11-27" version="1">MKYLSIAANYMRHGKSEQVNRFYKTENPHDNMATDIGPREKVLSFKPSQYISIMTSFDLDPNFVKGLKFLHSKHPDSTAQLKDLVDEVIAQSKQNVHLKDRYTAIKLEDSKLHIKKASRETSDSSVFSSKYASEERDRKAERKQLEKSKQDNSEIEAKIPKLEPPQVCSPSYPSSPPPLDQYVTKKEEESNSSDENQLSGKFMGSSDENLAADEFAMEIGLACVICKSLDVTQGNQLIECQECHNLYHQECHKPPATDDYNDPRRVWYCAKCVKSMKKIATKTQKTAKSGVATSSKESTIQLKSTRSEGSPPAAMLPFKRPELKTTLSQGSSQTANKPIGLAGLAANFGGRTSSSTSSLASSTRGTKAAVSGGGQKSHVPFSSSSTKASSLSGASLSKSASSLASFQSSGASQSSAGAKAAAPAAKGLSLLSVAVASASRGASSAPSGNGNSGHKAPSCSPLMSADKRLQIMKKKASKMQERRRLSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJ29</accession>
    <name>A0AAV4SJ29_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_615901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009712">
        <property type="protein sequence ID" value="GIY33979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJ29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7566" checksum="DEBAD6C2794A3680" modified="2024-11-27" version="1">MLSMKAIGGAVTGTCSPAMMMMVLTAPASTNLGRMGDPRANHIVPPDFGTKPSTPTEISRCMVFTMEECSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMR9</accession>
    <name>A0AAV4SMR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_603141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009783">
        <property type="protein sequence ID" value="GIY34546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8230" checksum="FAE47F5E82305F65" modified="2024-11-27" version="1">MSPGAVAKKEKAAFPTYVMHLLKLMALEIAVMSGFAECPNDFCTVHAFLAQEKKMILSVWNVMKFDKSSSDVMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQL0</accession>
    <name>A0AAV4SQL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_741171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010039">
        <property type="protein sequence ID" value="GIY36390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18281" checksum="7DB0CBA01366199B" modified="2024-11-27" version="1">MHPCSFLLRLRVKSEIEAGLCNKKALVQEASHSITAKRSWRSIQLDKRFFSGENGKEGRNNGSEGEVEIRVKPEIEADLSNKKALVKETSHSITAKRSWRSIQLDERFVPGENGKKKGAITGEGWREEGREQNEKRMRNCHPGRGSVSATNGFMGGFPGSSLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUI9</accession>
    <name>A0AAV4SUI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_147241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010249">
        <property type="protein sequence ID" value="GIY38023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13990" checksum="A45F19A8D97D5FEA" modified="2024-11-27" version="1">MRFSESLIFSKSFQKQEESREVRRGGQHKKLGGRGLDYRIALTRLGKPKCFYFSPGELFLLVRREPPVQIKSTQHPLIIRALSASLRDVIRKEHFVFRTEWGTPFNMGCRAFELRTFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYJ8</accession>
    <name>A0AAV4SYJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_216001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010074">
        <property type="protein sequence ID" value="GIY36678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8692" checksum="80B27EE5B63C595A" modified="2024-11-27" version="1">MSETFMNVSDDQEESKDFDENALEKRNQELSLAERASRKDTQRTTIRPSRPASSSCSSLRAAIIRSLLSRQTEGRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0A2</accession>
    <name>A0AAV4T0A2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_237985_1</name>
        <name evidence="8" type="ORF">CEXT_542291</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010365">
        <property type="protein sequence ID" value="GIY38856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY38856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="20920" checksum="1D1EC39C8A8DB0A4" modified="2024-11-27" version="1">MANKLESNKLQMKECSVVLNRIDYSISSCSEDDISSYSEDDISSYSEDDISSYSEDDISSCSEDEIKAKDLSCKSCKETFKTHASLLIHQRKHKRNAFKCVLCSAAFKLRQHFYSHMERHHPEVETYVCDFPKCEKSFSRQKQLKDHLKSHWKYMCKFCKKGYISKKYMKWHVKKIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEY2</accession>
    <name>A0AAV4TEY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_188331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010961">
        <property type="protein sequence ID" value="GIY43325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043808747" evidence="1">
        <location>
            <begin position="19"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15164" checksum="4E6E030373DC3579" modified="2024-11-27" version="1">MAEIFSGVLVLLLRNTLCVTTQSESLRFAKRPFILQFGGVIVQKTFAHPQSSLGALDQIFLQNKGRNAVFMGQPKALDFSTNDSFSPSVLRTGPACVTGVSREAVCFPRGPPLSACDLRRERLNGLREPVLSEKWPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUZ3</accession>
    <name>A0AAV4TUZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_372631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011799">
        <property type="protein sequence ID" value="GIY49117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10650" checksum="03BEBE67E1CCD963" modified="2024-11-27" version="1">MQNNVRPTMPSRGLSVFAFTKLNVCFCRGRLFNYRLTEGLICQPTRGCRWRSSKRFPQEVLRKNVLTAIPPTKKGDREMRVQAFDDPVRCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U452</accession>
    <name>A0AAV4U452_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_719031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012253">
        <property type="protein sequence ID" value="GIY52525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U452"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20897" checksum="773DB31E367D9F9A" modified="2024-11-27" version="1">MIIDWILGSHPKLCPGEKLNSMQQQSNYQESQQWVSEARVAAGGIIEKCVAKEKLDAARTRSYTIQCKIKSICVNTFLQIIQWPPRYCQQTIADIPVNIRQDRRIDRYAPGLGRNNKYDHATQRLGVLRFHMRRITNLYLFETLVPAVLFRETPNVVKYSLGFEGGCTVVIWFEVQFKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7L7</accession>
    <name>A0AAV4U7L7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_149211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012397">
        <property type="protein sequence ID" value="GIY53728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11251" checksum="91CAFB665A87AA2C" modified="2024-11-27" version="1">MRNTPKPTGPPPDLITVATLTMEYPHMQDSDTSGSVGGGILKAGDLRAYHCNNIAFTMRNTPKPTGPPPDLITVATLTMEYPHMQDSDTSGSVGGGILKAGDLRVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9E0</accession>
    <name>A0AAV4U9E0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_543521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012509">
        <property type="protein sequence ID" value="GIY54373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9E0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="44" mass="5044" checksum="E0995CBF110D645E" modified="2024-11-27" version="1" fragment="single">MLCISVENSPLFDRYSASSKDEFWDALSSNYDYLMDDGLIATCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB74</accession>
    <name>A0AAV4UB74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_375191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012560">
        <property type="protein sequence ID" value="GIY54870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11647" checksum="1946DFE8BE8ED0BE" modified="2024-11-27" version="1">MTLSMAVGCYRLANDVPEIFLKVFNDEFKANFFTKGLFENINIMCDFYNRDTDLKEIVVMQLSQVIEKAIDCEIFKLEVKQPGCSIPAIKDVFLVNKILQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URS7</accession>
    <name>A0AAV4URS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_190101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013350">
        <property type="protein sequence ID" value="GIY60611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="8785" checksum="360A7064FBA181FD" modified="2024-11-27" version="1">MTSYCLINCTSDSTEIISYTFPSDLTHARWGVTGSLPPPALCATINMTAVPSHPEGPCLFVAAALGAVNVLTAIAYVSHSQCAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9M9</accession>
    <name>A0AAV4V9M9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cilia- and flagella-associated protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CFAP20</name>
        <name evidence="2" type="ORF">CEXT_795851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014179">
        <property type="protein sequence ID" value="GIY66955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="22792" checksum="C4B72DC23673CE56" modified="2024-11-27" version="1">MFKNTFQSGFLSILYSVGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEILGNNVSTAYITCPADPRKTLGIKLPFLVLIVKNMKKYFTFEVQVVDDKNVRRRFRASNYQSTTRIKPFICTMPLRLDDGWNQIQFNLADFTRRAYGTNYVETLRVQIHANCRVRRVYFSDRLYAEDELPAEFKLYIPAHTRVKTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCT6</accession>
    <name>A0AAV4VCT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane protein 87A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tmem87a</name>
        <name evidence="10" type="ORF">CEXT_124701</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014343">
        <property type="protein sequence ID" value="GIY68226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053937">
        <property type="entry name" value="GOST_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF1">
        <property type="entry name" value="GH17801P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06814">
        <property type="entry name" value="GOST_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043461638" evidence="8">
        <location>
            <begin position="19"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="GOST seven transmembrane" evidence="9">
        <location>
            <begin position="292"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="569"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY68226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="630" mass="71469" checksum="FB4BCE150B791A73" modified="2024-11-27" version="1">MCKILSVFCVLFISYVSCFPDPGQWSQSVFNESVALFGAHKPLYAGSSIHITVNCEPHQKIKLQWVLRQTSCYAEYLESSIYITEVLKQYFVCPMSSMNSFSKIRFFKSDPVIIECSNRIHLELVNSSFLAISNEMDVPFECRKNFYTSTDDNKDIKNDGNIPPKFLALRKLETHPDVWENINGSTMLSTSGTGGRSKRSIQSQDSKTAKENFADINYKNESISDQTSFGRVYGSFSSSSNVKLGSKLTSVDMDGIYLFILKVESVDKQTFNISVDIGMKGDYGYLSAVDYPLLIFYGVMCGLYVIYAIVWLLLSALQWRDLLRIQFWIGAVILLGLMEKAVFYAEYQSINYTGQSVQGAILFAEILSCMKRTLARMLIIIVSLGFGIVKPRLGPTLHRIVGVGALYFGFGTMEGCLRVLKPKTDPGNQALMAGVPLAVTDSGICWWIFSSLVQTIRTLKLRRNIVKLQLYRHFTNILILSVIGSVAFMIWSIHAHKLVNCIPDWKELWVDEAYWHFLFSTILFVIMLLWRPTKNNQRYAFTPLLDAMDDDDDDDEENLLPNDAFAGMKMRSSKNNTNSPRSDDSKSKQDEDLKWVEENIPTTLTDVALPSLLDSDEEIMTAKFERSKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFB6</accession>
    <name>A0AAV4VFB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_32051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014432">
        <property type="protein sequence ID" value="GIY68743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23203" checksum="50C0AA3FD06D9A4C" modified="2024-11-27" version="1" fragment="single">MWLQHIDPKHVAPAHRASKHVHSAASSRKHGTSTSSLKHVAPAHRARNMWHQHIERNMWHQHREPKNMWHQHIEPETCGTSTSTLTCSTSIESLNMWHQHIEPETCGTSIDPKHVALAHRPETCGTSTSSETCGTRHIEPPKHGHQHIEPETCGTNTSNPKHVAPASNPNMWHRAPSVTRHQNHELNIYYVDIDANEAIICVFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLW1</accession>
    <name>A0AAV4VLW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_774761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014743">
        <property type="protein sequence ID" value="GIY71023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11266" checksum="78937B7A977684A3" modified="2024-11-27" version="1">MISTSDVHSKTNGLGKKRKGGRPNGIHILQDIDIAGSFRWNRTEGGGQRPIVKMERLIEGDTQNRDQKRILSCIISSRMKEKFGKSRKERRFSALIRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMW3</accession>
    <name>A0AAV4VMW3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_771601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014842">
        <property type="protein sequence ID" value="GIY71695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11872" checksum="27E37454F505B8DD" modified="2024-11-27" version="1">MILDRGDSGDVQLRRKAIQFLVVLRCCCLTSGWVKVEDGGPHKVQIVASGFVLPGRNLDLDQSTPRWTSAVTRSGLALISGGGWEMSGFLTVTGRWIRRNGKLEKMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPI5</accession>
    <name>A0AAV4VPI5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_184501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014926">
        <property type="protein sequence ID" value="GIY72292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043629792" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY72292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7148" checksum="C523790C9E8DB370" modified="2024-11-27" version="1">MSCSVQVLMSFSILLAHTPVLQVCSVFLRVRLFLRPSSCLPNAPTTGLSKYQTGNIGKTPVPVEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRR8</accession>
    <name>A0AAV4VRR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014982">
        <property type="protein sequence ID" value="GIY72703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="61" mass="7305" checksum="2D0EC5A54DE3FE4F" modified="2024-11-27" version="1" fragment="single">SPLAGMRHTNYADDDDDVQQCVRKRKMGAHEKRKWKKRKKGNVCLRYSQRSVFIRTVVNLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVE3</accession>
    <name>A0AAV4VVE3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 4 gamma 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EIF4G3_2</name>
        <name evidence="2" type="ORF">CEXT_149091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015190">
        <property type="protein sequence ID" value="GIY74247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF78">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="209" mass="24072" checksum="CE781DF96A11FCBA" modified="2024-11-27" version="1">MFINAAINQVLERSSQARFSLGQLLYSLLKKKIITFDQYKKGFKSVLEIIDEYALDIPLIWDYMGEILEPMIEDTEFPLKLIKDVLKPCIPSQTAGMLEKFGENLAYNGLIFLGKDINIPEFIKKHKLEFTVSPTKVKPRTQMSIEELRKNLLSLFKRTENLEEMLNVSDLTELSFIRAFVTAVHESAILNDEGSYKLDQNKLKTMAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VW74</accession>
    <name>A0AAV4VW74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_731251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015245">
        <property type="protein sequence ID" value="GIY74691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VW74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16281" checksum="F902B03E9BE109B2" modified="2024-11-27" version="1">MCVVPAWKKGASRRTQPWGAARESSTREKRTRKEREREERGMGKMSVKAKPKQADSQKTQLVLADSAVQTLESRTEVEQCMATVLSFHMPPFGICRNCPQERMVQYFHAVSSRGFHAFRVKVRKSERVGANKVTDEAIRNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2V1</accession>
    <name>A0AAV4W2V1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_391511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015387">
        <property type="protein sequence ID" value="GIY75780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2V1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10173" checksum="4BB465AB87261B63" modified="2024-11-27" version="1">MGLEIGLNSITSRNFYKNVTRRMYGTNREDSKPDIAYNVLNSNAKRSNDEDDSECEEKSATSADALRAVHHLRNVFTNSEREDVYLKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3M6</accession>
    <name>A0AAV4W3M6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_191361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015508">
        <property type="protein sequence ID" value="GIY76640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3M6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12817" checksum="497E164CDFCF2FC5" modified="2024-11-27" version="1">MSCSSTYKDLHGDFRRRLISRRDQRDQEYRKEARREVVTSGRKSSHVVEMESSRFHLRALQSDDGTERGLLLECPISHCTRYVLTNFRSEGVPSGKPQGLVNKALFGSGTAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WA26</accession>
    <name>A0AAV4WA26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_153891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015790">
        <property type="protein sequence ID" value="GIY78749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WA26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="316" mass="34834" checksum="521343D37360FC61" modified="2024-11-27" version="1">MKLHSRITKSVKLDSRICKSVKFSSRIAKSVKLGSRTIKSVNLDARVVAIKLHSRITKSVKLDSRTCKSVKLSSRIAKSVKLGSRAIKSVNLDTRVIAIKIHSRITKSVKLDSRTCKSVKLSSRIAKSVKLGSRAIKSVNLDTRVVAIKIHSRITKSVNLDSRTCKSVKLSSRIAKSVKLGSRAIKSVNLDTRVVAIKIHSRITKSVKLDSRTCKSVKLSSRIAKSVKLGSRAIKSVNLDTRVVAIKIHSRITKSVKLDSRTCKSVKLSSRIAKSVKLGSRAIKSVNLDTRVFAIKLHSRITKSVNFIPEQLSVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDE3</accession>
    <name>A0AAV4WDE3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Shavenoid isoform B-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_223500_1</name>
        <name evidence="4" type="ORF">CEXT_618501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015986">
        <property type="protein sequence ID" value="GIY80244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057507">
        <property type="entry name" value="Sha_B-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39387">
        <property type="entry name" value="SHAVENOID, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39387:SF1">
        <property type="entry name" value="SHAVENOID, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23328">
        <property type="entry name" value="Sha_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Shavenoid isoform B-like N-terminal" evidence="3">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY80244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="588" mass="65701" checksum="90A2CE46272765B9" modified="2024-11-27" version="1">MDNVFHNFDSVVYLGLVSLETIGHVTRDYFGDIFTLEDCDPNDLCNKDGRRAALIPGESCRCQCAPSHYVFREDIKQCIKDIGECPLFMFARPYAVEKIPLVFLPMTGQLVYPGAHLTVSGITRLSSSKHLSCNVKASLLMTSHGFQPIRTPSQIFGVYYDGNKTFLQWLGNDDDRRRLQHHLVLIRLFCESETSSGGTFEPCAALRIGWAPGLEPEFADQPTNKNNFIIIGFSIGILGLIYVGAILIYLKVRKNRREAARQGLAPSHSSIEAVDEDTSPSTQLRNAYINNLVQEAEFTTKSSIKGSSSHSATTEHDLSSLDNNYRQLDSSTSYDTKHIKNSLAESSKGCSEDPNEIISPPSQDFFIHFKERDIDGSNNRKSSFRKFSRKVSTPAVTKKIESFHGSNLGAAMLEAKLAPPLPPPRNSKSKSKKRAPSPPSGDKDYCRESPSPVSLKELGGSLDRKKRKVSSSQSAESYSKFDLFRLDLYEKINRISNGDEIILEMSSGKKFKDDLDVVSSSTGQERNIGSKESCCSTLEHPSGHQDAKISRRQLLYKLQETETISDTEEEKPYVEKHVKAKTEQVKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WED2</accession>
    <name>A0AAV4WED2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_474011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016098">
        <property type="protein sequence ID" value="GIY81216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WED2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15302" checksum="CAEBCCCC34C2B7B0" modified="2024-11-27" version="1">MLQLGRLLRNMVALGGVVGTPKWFTRYRFMALHNCPGIKNNRSSINLFRLSIHIKITTNEFSASFPKLLMSIKPALEIIKPLNRKVQEDKNVNRQQAELSFSRPQIVLAPESLITGYINKRSEKYKQKQKAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGE3</accession>
    <name>A0AAV4WGE3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_381901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016058">
        <property type="protein sequence ID" value="GIY80884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7693" checksum="6522D6DCEF0420B3" modified="2024-11-27" version="1">MEGVDETSPVSAPREADNLNALNFSSPANGSGPCSGLYSCVNSLGKWLFIRPTPTDHRPVARVTLLPSPVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WS18</accession>
    <name>A0AAV4WS18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_152401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016504">
        <property type="protein sequence ID" value="GIY84333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WS18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15516" checksum="996A698FBBFFC75F" modified="2024-11-27" version="1">MHFVDDPRTSPNRVRVSPTPSTPDPSTASASTRNNKNRLQCLSNAARSFFPQNKLPSFWKKKRQNCAFLHSKKCSIYKKEHHFEQSGRKKKNRIEGTGIKNENDYRSRLPNDFGLNLLSPGEMSQMEYRLFVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTN6</accession>
    <name>A0AAV4WTN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD repeat, SAM and U-box domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Wdsub1</name>
        <name evidence="6" type="ORF">CEXT_631692</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat POC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016591">
        <property type="protein sequence ID" value="GIY84903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="10"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="66"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="160"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="264"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="5">
        <location>
            <begin position="367"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY84903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="413" mass="45833" checksum="188B2C7211993891" modified="2024-11-27" version="1">MCDVEIVQVLEGHTSDVMGCDFYNGCLATCSGDKNVRIWFQKLEENEIDLDSKRQIHFYEAEFSPLLGHTYGVNCVRFSPFGTLLASCSTDGRVILWNAQDGKKLDEIRHLEGPPIRVCCFSSASAMFATGGDDEKVVLWDIATKSVIRHIFKFYYFRVLEGHEAMITALAFTPDGIFLLSCSTAGEIMLWDARYGHGKCLSSVTNAHDLGILGCDSSPQYEAVSENGFLVGNYTIATCGNDDFVKLWCVEASSTKRISLKNTLEGHSGNVISCRFSCDGKILASTGGDRVVILWNPKTGEVLQKLEGHNRYAVTCCAFSNSALLATGSNDKTVVLWNLDKKSIDDLSKTNIKEFKILPAKKSFLSWTVEDVRSWLKSLNLEEFSEAFSANSIDGKELMYLNHENLLCIFKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X185</accession>
    <name>A0AAV4X185_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_326061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017115">
        <property type="protein sequence ID" value="GIY88872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X185"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13357" checksum="C23A7C8ECE49DD0A" modified="2024-11-27" version="1">MSEFSMNEVLKNGGKLNRAAAKNKPKENHAATMFFSHAISTLAHAFWIHLREFFDLPPPTARWGDNRVTKSDCGLFPAENISIVLSFFFPSVQIFYFRLAVIMIIIIDSSGEDILFCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3R1</accession>
    <name>A0AAV4X3R1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_715141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017064">
        <property type="protein sequence ID" value="GIY88413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3R1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13403" checksum="3F0267EC1AAA4CB5" modified="2024-11-27" version="1">MRGSIGVQQPINTASSNNTGMPDLYPPLPACKTARNYESLQKRHESLHFPNACALCEKFKIALIPLIRFRAQTIPDKSWIHSKLLRADYERKINYSRQLIRCLNQLLSFTCFHSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5R9</accession>
    <name>A0AAV4X5R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_364241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017269">
        <property type="protein sequence ID" value="GIY89903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="12912" checksum="FA4D36A2240DF470" modified="2024-11-27" version="1">MNRLERGGSNRLVRIGLDLGVQLGSKRNGLSLVGADGLTKSGGEIRDAVRCLLCPGLLRQKSAILHIERAGVILSARTNYTKKAIIEASGIHGLSEEHMTLALWKGGEKVKKKKKKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9C4</accession>
    <name>A0AAV4X9C4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_472911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017389">
        <property type="protein sequence ID" value="GIY91217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9C4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14872" checksum="09E8F77EB2616F08" modified="2024-11-27" version="1">MCECARNAQLGEERLSADYNGINSGAPLPTSREYAPAAMKAAIRHASLESELQDALFARVQEGRWLSPWLLSVCSRKRVIDAFLTWFVSKQHAKQRLLMDAQHANPPLIGPKKFWSHCPHFQKKQLLKPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBC4</accession>
    <name>A0AAV4XBC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_500941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017398">
        <property type="protein sequence ID" value="GIY91275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7728" checksum="75F112772690CD54" modified="2024-11-27" version="1">MGHCAQPSCLAAILEARPEAGKTSLITYSAESSPSNNEKGRKRTCVLIVTAQKKCVWLLHTLPSFPVFLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDC8</accession>
    <name>A0AAV4XDC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_796801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017460">
        <property type="protein sequence ID" value="GIY91789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8604" checksum="31FB9361B1A9A912" modified="2024-11-27" version="1">MPHTMICMFYLPRARIDVCRNPPTARFIDLNQILRGWPARTYDWDDPLGGGQTPPRKSGSRGCIVGHCLSPVLHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEC9</accession>
    <name>A0AAV4XEC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017606">
        <property type="protein sequence ID" value="GIY92964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11714" checksum="4C1E47EFB3601DFF" modified="2024-11-27" version="1">MDYWKVGWTVIVFHGLLENWVEVIVFHGLLESWMDGYCIPWIIGKLDGGLLCSMDYWKVGWMVIVFLDYWKVGWTVIVFQELLENWVDGYCVPWFIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEZ6</accession>
    <name>A0AAV4XEZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000129">
        <property type="protein sequence ID" value="GIY92359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9057" checksum="36C1F5D9A69D3733" modified="2024-11-27" version="1">MLFNKSAGIALLPERRKAALLQGVGCVGVGVGCARRPRLQGDRSHNSSKILSRGQHTDLVTGVFSRMEYYNSLKISRTPLDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGS1</accession>
    <name>A0AAV4XGS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_658051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017714">
        <property type="protein sequence ID" value="GIY93853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12023" checksum="C0F738AB58509D2D" modified="2024-11-27" version="1">MVLEGRGLTLFPQQTAKRMESRHFSPEDHQAAECPPPVLRRERKERISDAAHRKGAGPSEGDPPDSLRKAQAQVPHGLPEAGSVPGGDLERACNSCSTRGRQKNSVLFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKF1</accession>
    <name>A0AAV4XKF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_369401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000386">
        <property type="protein sequence ID" value="GIY94410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="21088" checksum="E2C33C7463E867D9" modified="2024-11-27" version="1">MNPSKDCIKEGFLPIFLLFHLQGMGTLPCPNCFARSNLFKVMWNLTKYRFPCILGCITVIQTLWLCFISNNKDERAALIVLFLQLWIYISVFRSRTRIRLLTEELFKISNMLRVYTIQKKKLLKIYIWVYCSFVTFVTVFFEVTFFNTGLIANKQQRLRNSELDPEHLKARLTHWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNY2</accession>
    <name>A0AAV4XNY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_233101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000708">
        <property type="protein sequence ID" value="GIY96837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12376" checksum="88343F85EF741E00" modified="2024-11-27" version="1">MLPGAVPSAFPLLPSILFAETSLIPLMRGYGICIMNEGDRVGERGGHGFILIKNACMPPKVAIGVEELERGSVGCAAVESPGWGFRFCLVLAFVFRGFELTHPLSVVYLAAGYCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPY5</accession>
    <name>A0AAV4XPY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent RNA helicase A protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dhx9</name>
        <name evidence="2" type="ORF">CEXT_227661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000604">
        <property type="protein sequence ID" value="GIY95970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000028">
        <property type="entry name" value="ATP-dependent RNA helicase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12481" checksum="22C70D585C55E3C4" modified="2024-11-27" version="1">MLLSPEVPIELPAGFQTEKQEPADLPEGGPLAPHIHGLRIRKKMEEAEDLDVNSAIHGNWTLDNAKSRLHQFLQASKLNQDYKYSVVGPDHNRSYLCEMNVYVRQLGRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVB5</accession>
    <name>A0AAV4XVB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_703121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000999">
        <property type="protein sequence ID" value="GIY99067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17334" checksum="61B0C06F971E71C3" modified="2024-11-27" version="1">MFGRGNHIALKERDLYKISLSEHLKHWDACLLLSEHLLETNQTRSIVRRIMPDHIFHVLAPSLPINRRTLKIKDNGDSVLPKNIFLLRPASQCMKDGVKRPEIAFSSEEKGDCWGGHKFLHTRANFPLLKDRVKNNWGLPEIETFLVFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVH6</accession>
    <name>A0AAV4XVH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_549021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018235">
        <property type="protein sequence ID" value="GIY97964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7723" checksum="B35F95D6EEB21CD7" modified="2024-11-27" version="1">MGTEAADVFDICFVEQRHSEFRGPHAALHIQRTALFRHGSKWTDDEFQGVLVCTDDKFQGRRENNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWB4</accession>
    <name>A0AAV4XWB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_46951_1</name>
        <name evidence="2" type="ORF">CEXT_799311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001048">
        <property type="protein sequence ID" value="GIY99442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1101" mass="126884" checksum="3C2F329A719B6B9C" modified="2024-11-27" version="1">MVAWPSGLRRWFKAPVSSEAWVRIPPLPAEELRLIAKTLADESKKSIRSAFRSKTWVPLKVDVFPAPIKGVLKSKKQQSADNTRHVTFNSDPEIHYRTASETSSASTPKSVQNRKEKENDFHLNTKMNDKSYSCTFPKTPEEKSEAERKFDELLNEKCSWSYKSIKTIQCQRQIENKKSSIYQIQSSTIETVNIAENLYDDNYCEDKEFGDNNGEIKNEKKYQRKNKKKQPRKSNNSRTIKHKNSLINKNSCTFNKVLDTDIQNNVKTTRTKRNVKVISYEEVSDVEYVSSSSDEGIVLQSRIFNGNSDDNDNSIRSDDDEITKIYPSNNQEELNKFTTCNSFNSNCNSEIPTQQELNENVSNFVEENNLDSERLAVIDQEDISSKNSSIEKVMEENVNTSTLQLSSLSELDNNENEVNKDNTEIKTQSSQTDLSLKILQQYNNISAEIQSVCNELETPKSTIEDEILEDFLNGSFDINKYKLKSKTPEVHQIDLNEAKFKNNNKNDSVSAVKKLPNKSDLKKSNKIKDLNKNETIKSHNLKNNIRNKIDIEKSQSDDETKIQFKRSNTKVRKSVPHNQQLYIGCETIQNDNLQDRITRLQSLNFKSHSKNLSDPPKNTKDKIEKCDGNNKEKNIRQTALTVKKSKMNNLINTDTNSLSSVEEDKKCVRNSEDEVEINFPIFEERQYSAKYKRSKIEYKTNIYDEEQETNEKNVLNVEKVTVKQNTKIKSNKKNNTHNVILNKEFNSPFLNKYNAITPYRKAGNVLTKSETNCPITSNLKSKDKKQSPKTWVELENEILNSDENETSTFKKCTFFPTEELISDNEKLHSFKRNNSVHYSEIEDEDSQDNYGIQNLVKENSFTLVKSNTNPEITFDSPNASIINKVIMKMQQCTSPVLMPNKEIKGKCNEKEIICQVQLDGDSTKNNEISNMKTYQNKEKREKCNKDSYEDNETILSQMSDLQLNILEEMNKETAVQIPTKGIKMPDLNLQKNSKKISNITSVKQEQEKNYSKKEYEEYLEKLFHVDVLKDGSAQNEFLSDNNKGKKKYKRSSSSEKVQQKKMIANSDDELFSISSLETDLEDENEQPSQKRASGLLADFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWK4</accession>
    <name>A0AAV4XWK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_158091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018384">
        <property type="protein sequence ID" value="GIY99107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10471" checksum="CD60EEF132A3B1D6" modified="2024-11-27" version="1">MLASWFAPEMQRIIKVSAFLQDSGFSQPPHLQKIPFSDFRKNLVQVKADLSRIIAEHVDFLCVKSRCKNMLASNLFEQIFVCVDNPADVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX98</accession>
    <name>A0AAV4XX98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_664091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000931">
        <property type="protein sequence ID" value="GIY98520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9485" checksum="BF2348FD909DF97C" modified="2024-11-27" version="1">MIILEGSIPQKLDSSFQQLSMQSNGQTLSEDTSYKHSIRKAWQRWEEMKQGKIQPRASKRYTSTSSKSPSVLNVAALTALETPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXK8</accession>
    <name>A0AAV4XXK8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_49171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018370">
        <property type="protein sequence ID" value="GIY99023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19554" checksum="B2D9F3EF3012768D" modified="2024-11-27" version="1">MTSCESPLGSPGSHACHIHEACRTADDEDLVTAPMVLPNQAGVTRSNNSPIRMKLQVLFAFIELLVMALSKIFIQTSFGAAFSSVNSAMFMERYTLNGFNPLAVCIDLFPRLGVTLDDAPGLLKKRFLNWECSILLVHSLDQLEEVLLVYQQRRRRRSAGARSLLTYLLSHRQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY09</accession>
    <name>A0AAV4XY09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018352">
        <property type="protein sequence ID" value="GIY98879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9240" checksum="78057EF33149A7A0" modified="2024-11-27" version="1">MNWVEDSSDWKSALLVDGETTLARNGRSFLLPFTLSKLAFQRKDTQIQFKSSCKISCRIQVFSSGSLFCFVKEIFSTDLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y695</accession>
    <name>A0AAV4Y695_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_748591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001312">
        <property type="protein sequence ID" value="GIZ01506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y695"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14411" checksum="2B2CD697A1F58773" modified="2024-11-27" version="1">MRNPTTQLEYKVGTFRSPTDVSMSPFQYHLIHGNANLIHPPPPNLLSHLRHYSEMIPTKQAVSRSSHHSLLQSIDSWRPFPPEVEPPPPWVLPFQSTTPSTHSPAISSAPSGDKLAPATRSDNDGYPGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8I1</accession>
    <name>A0AAV4Y8I1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_464861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018867">
        <property type="protein sequence ID" value="GIZ02834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8I1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11835" checksum="51867AA7D895E513" modified="2024-11-27" version="1">MSEKKDSETLARWICHDEKGPEEDLLQQHDIKQQRNAILSCYSTSKHLRRTNFKTSPFCSSSIFPNTCSFGALALFQLELDFSLRVDLQRPGRSIRCTWLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YA54</accession>
    <name>A0AAV4YA54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_32571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001513">
        <property type="protein sequence ID" value="GIZ02841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YA54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="28" mass="3052" checksum="7C9F18AB413DEC24" modified="2024-11-27" version="1" fragment="single">MSKYLYLEDGSLEGPDGLGTCSRGDKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAI5</accession>
    <name>A0AAV4YAI5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019012">
        <property type="protein sequence ID" value="GIZ03919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10717" checksum="321F88975E4AC436" modified="2024-11-27" version="1">MAVDRPEGESFIQQKLLTLLISTWFAVPAQSVLLSGQKDTMTNLRSCRKNSLVHQIAAYEPEAEIWRNHLFARLSLDHKHCRFRSSQKNSTPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBS4</accession>
    <name>A0AAV4YBS4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_21091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019168">
        <property type="protein sequence ID" value="GIZ04936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023340">
        <property type="entry name" value="UMA"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51497">
        <property type="entry name" value="UMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UMA" evidence="2">
        <location>
            <begin position="83"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ04936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15450" checksum="80C036560A718F6B" modified="2024-11-27" version="1">MFDVFQNVLFGKKKSSSEADKEKSCSDDFVMIGQTSNDLGAGKDAESNPNERPFPKFGESFLPDSVPEVSPVKKEAHPQIMPLQDVPFTINSSLYASSKLDQIWKTIAQSISSIENSKTFQEDYDFSLEKSVISETANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7B6</accession>
    <name>A0AAV4M7B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fatty acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Fasn_3</name>
        <name evidence="1" type="ORF">CEXT_56041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001896">
        <property type="protein sequence ID" value="GIX67730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10316" checksum="070FCBA8554F2D95" modified="2024-11-27" version="1">MYTEGLNPKVERLYPSVAFPVPRKTPMISNLIRWNHGHSFHVPVYSPVIRGFRREFHFDKEDSYLLEYKVGAGPSSLPQPFSCWRGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBW8</accession>
    <name>A0AAV4MBW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_800891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019626">
        <property type="protein sequence ID" value="GIX69871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14019" checksum="73EC328374746252" modified="2024-11-27" version="1">MSIRSFKRKTFPIPVTKSFLPTVKSFLAYQRWRIHTPIVNVDKIFSTVDVSNTRYHVISANCKIFPHLSKMAAWATSLMFQPPRITWELNLPPVDFPRCERNVCSGSGCIRRKMLHQIAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEK5</accession>
    <name>A0AAV4MEK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_560631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019648">
        <property type="protein sequence ID" value="GIX70107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10746" checksum="0D4AB8A6C67A31AF" modified="2024-11-27" version="1">MDIGHNLQILDLDIGHNFQILDPDIGHNFQILDLDIGHNFQILDLDIGHNFQILDLDIGHNFQILDLDIGHNFQILDLDIGHNFQILDLDIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKZ6</accession>
    <name>A0AAV4MKZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4211 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_181227_1</name>
        <name evidence="2" type="ORF">CEXT_393811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019863">
        <property type="protein sequence ID" value="GIX72634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12131" checksum="34B335822D44608E" modified="2024-11-27" version="1">MNSSPWSPYNNQQSFLRSGSPHLPHSISLEDPLNSYGGGNSNSLHLSSCQNLQISASSRANDPSAISLMPNPSYESLISPKEATEYFNNCKRKSIFNKQLHSVTEFVVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNG2</accession>
    <name>A0AAV4MNG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_736231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020011">
        <property type="protein sequence ID" value="GIX73966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8071" checksum="897CB83530598D35" modified="2024-11-27" version="1">MNNMKTPFPTTKEGQSLSLVYSSTRMIYGWVKESQWKVNGEEDPVYLGLCQPGIFVPVYLLIVARMDRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MU05</accession>
    <name>A0AAV4MU05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_669711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002620">
        <property type="protein sequence ID" value="GIX75773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MU05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9106" checksum="5A18B4BB16840F3E" modified="2024-11-27" version="1">MGEDTFQSPSHVPQPHFFPLQLKTFPDHFEEVVGTGLDYRENYYESGFCQISERPPISVPNPLTTVQPKQKRRRENTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0R0</accession>
    <name>A0AAV4N0R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_289611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020395">
        <property type="protein sequence ID" value="GIX78226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11983" checksum="CEC4CE8F5AB73EBC" modified="2024-11-27" version="1">MKCLQITSFPEPQKRLFLFTTMPHHYHDSVSQAEIFNAKCLKQKAIPGTLSNLLPLQDRPLSPIRNNSFQLCSSRILPPQLTSASMTIDKRASISQSVERAFAIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2M0</accession>
    <name>A0AAV4N2M0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002894">
        <property type="protein sequence ID" value="GIX79060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2M0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13381" checksum="3137E77B3829F197" modified="2024-11-27" version="1">MDKKEIFFSKYKDIKNRGSGPGSSLLTRPSTFLKTLDSTDNDFFHSTGGTNRCWAWAIINSDISKYSNFAGTKGPHRDCSANLKDRPDNVHLIVVDFADCRFTAPIVERTYSFLTATFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N568</accession>
    <name>A0AAV4N568_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_439981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002980">
        <property type="protein sequence ID" value="GIX79862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N568"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="18432" checksum="CDBEAF38801F18F4" modified="2024-11-27" version="1">MRIEYRFRLACAYCFKDSIVSLWSVMSEDEKEMESDRLNASKWIPYLMEKDKTNWPKSSQDLVLENWLKSLFWNTTAIRNILQLIKPEERPVFLYKYLDYDDKYPHPQKSVCTSKLKNSIGLNFSKELCVYIEFLLSLAVAGYLFEYCKSLLSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6H7</accession>
    <name>A0AAV4N6H7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_104091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020569">
        <property type="protein sequence ID" value="GIX80101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6H7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8652" checksum="AD79DCBF6C1DDDD3" modified="2024-11-27" version="1">MAEMELEGAEGNGLFRTPWKYHCGVRMRFLILKRKRRCQEIITTQADRKMLKLNWPFLTTGIEQLKMLPKDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7V8</accession>
    <name>A0AAV4N7V8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_669431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020632">
        <property type="protein sequence ID" value="GIX80917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7V8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9561" checksum="7C82C2070F614AEC" modified="2024-11-27" version="1">MRVHPSSQDEVKVKWKMYGAKNEGKERTERHSDERSMADPLEKKREGIFRDGYSDKIIKTRRVSNHSLIAPSNEESDRLAGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NA51</accession>
    <name>A0AAV4NA51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein phosphatase 1 regulatory subunit 42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ppp1r42</name>
        <name evidence="4" type="ORF">CEXT_241081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020657">
        <property type="protein sequence ID" value="GIX81180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NA51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21340">
        <property type="entry name" value="PPP1R42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX81180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="35689" checksum="8607AFB90A18B6B8" modified="2024-11-27" version="1">MKINKELIQRCSSKNLLPIQQSDGLMDRITHLYLQEQHIKKSNLRALYLYDNKIEVIENLEDLVHLTFLYLHKNAISSIENMDTLSTNCSYQNLPEGQSFEFDPGTITCIAESLRVLNVSGNRLKSFLPLRPLEHLEHFTAEENVVCDLQEVVDVFENWKYARIVKISGNPVCALRKYRDNVVVSCLELEELDGKVVSQPYRNFLLNWKQCQTLQSRKKESYAVLKPFLEARKNQEQTVVTSQEPRSSSVAPKPDRSGSSASSSQSETSVSSKSRSKSAQRARSLQEVPLKLMKKFTRTDDDRSSPLSNRCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBI0</accession>
    <name>A0AAV4NBI0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_228571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003153">
        <property type="protein sequence ID" value="GIX81675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="15783" checksum="401B8A5C9F999266" modified="2024-11-27" version="1">MIKAKGTKDEQFSTGNGARSDIVPKVGNIFRLGKMITRSIFPNFFPFFFFGVLFLKGETPSCLSTGEIRYRRRPLIRKVTGNSLSDKSRAKMSGKGTFLSTLCLSGEVMQILPVHEPRGKTENSKSRKRGISCGSVLTNYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NF40</accession>
    <name>A0AAV4NF40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_175421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003293">
        <property type="protein sequence ID" value="GIX83108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NF40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10392" checksum="A6FB94E43CFAB29D" modified="2024-11-27" version="1">MYVTKKSSLPTFSRVQCLSAPSQLLNSGCKKQAGYSRRFHRWLGNAGVSQLKKFAAAAAVVCGQRTLKGLGQWNAGIYYISDVMIVPFVDRCLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGY5</accession>
    <name>A0AAV4NGY5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gypsy-like reverse transcriptase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_330771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003390">
        <property type="protein sequence ID" value="GIX84031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="38" mass="3834" checksum="FEF07A75ED20EC1B" modified="2024-11-27" version="1" fragment="single">GSKPSSESTMSTFASELKSGLASAKEDLLNVIGCPPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNG2</accession>
    <name>A0AAV4NNG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_716341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021133">
        <property type="protein sequence ID" value="GIX86357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043775049" evidence="1">
        <location>
            <begin position="18"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8091" checksum="7E8ED07D2ECA126F" modified="2024-11-27" version="1" fragment="single">FSCLFLLASLSLELCSLLKTLPKKNANFKLIPSLQSVFKARFRYKSPSGLEMASYSEIQQRIFLKRREFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR04</accession>
    <name>A0AAV4NR04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_762831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021219">
        <property type="protein sequence ID" value="GIX87262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="17718" checksum="22B1C61623A63907" modified="2024-11-27" version="1">MRGLHGVSLMPMMLAAWIKVETKAILTIHQHIITQLPHQPEPQRQPQLRAADPERAGRRQGRIHVPGEHGAHEEPGRVPRRARTVQLDAISSTVGVISSSVPMTGKFTTALVLKVHLIYLSIKGGFFGGGGGRVNKFMDSYQLEQLTRLEEVVSALYQWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUN2</accession>
    <name>A0AAV4NUN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_684911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003771">
        <property type="protein sequence ID" value="GIX88486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10798" checksum="E633FC1DC5435886" modified="2024-11-27" version="1">MQINLGSTFPFLSRVYVDPDPGKLERLFAADQHHKSSSREGRKKKTKSSILEAPLETQRGCDPFFLSVLESDGGTSGFPIAVVASAFRLAGIAFLANNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0Q4</accession>
    <name>A0AAV4P0Q4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Sodium-dependent nutrient amino acid transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">slc6a5</name>
        <name evidence="17" type="ORF">CEXT_778981</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021431">
        <property type="protein sequence ID" value="GIX89489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF321">
        <property type="entry name" value="SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIX89489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="28450" checksum="82EEFA3E615B1B74" modified="2024-11-27" version="1">MLFAIGLDSQFGMFETTISAFVDEFPSVLKKRKTLFTGFLCFVMFLLGLPCVTEGGMYVLQLMDWYSAAFSLMIISLLELICISWVYGIDRFFMDISLMIKRTPSLWWKLCWCYITPGTIICLLCFIVINHEAVTYDEYQYPKWAIVIGWMIAFCSIAPIPIIAVIQLLKAEGTFYQRLISCLQPTEKWGPALEEHRILYRKSLSLVSSRFPQKRESFVNPNANTTQGNNDGLCMVRTGDVLLTAESSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P141</accession>
    <name>A0AAV4P141_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_315931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003868">
        <property type="protein sequence ID" value="GIX89486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P141"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="293" mass="33574" checksum="F2FF7C3BA61EDD6C" modified="2024-11-27" version="1">MEPNVQPYPYHYNMAPKRVTRNNRCRNKVIGISSKWQKASKIRHLADKEWGKITTFATIAQLGNDINGESIVNQGQGTTVAEIPLPSSLPIRCTLVKIETFPDQKGRQESRLIKLITVLLTHEDIGILTKWQKESKIRHLAKEEWGKTVTEILLPLFLPIRSTLVLKIIEAFPDQKGRRESRLIKLITVLLTRALLRWDSVALVRHIVPSLHYSNIIRVTLARVVDTQMPPKFKRKEWTLVFEEADTLLSERSPKKSEEDECSKGRESIWERSEGTMACFTSKGNISPFESPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2R6</accession>
    <name>A0AAV4P2R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-B-cell leukemia transcription factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PBX3</name>
        <name evidence="4" type="ORF">CEXT_755261</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021588">
        <property type="protein sequence ID" value="GIX91522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005542">
        <property type="entry name" value="PBX_PBC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03792">
        <property type="entry name" value="PBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51978">
        <property type="entry name" value="PBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBC" evidence="3">
        <location>
            <begin position="51"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX91522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12084" checksum="0500F61D2F7BCB9F" modified="2024-11-27" version="1">MDDQQRMMHSVSQHTSVSMAGHVVPQHGYGMPQQPHGVDPTNQGPQQDQEIRKHDISEILQQIMNITDQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKQVSVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P435</accession>
    <name>A0AAV4P435_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_755511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021522">
        <property type="protein sequence ID" value="GIX90689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P435"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10121" checksum="DA777EA71A1B6FC1" modified="2024-11-27" version="1">MNGLKTKKKKNPMNPSVKVLVSFVNTEKSHIRGEKRTDKLDLRQVASMVLACFDACKELLQSFNVCKHFPTPPPTERRWFCRTHWCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4I3</accession>
    <name>A0AAV4P4I3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_335081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004026">
        <property type="protein sequence ID" value="GIX91433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4I3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="47" mass="5299" checksum="D5FE38F8CC690738" modified="2024-11-27" version="1" fragment="single">MISARDEDGSGSNKRFHSKCILVCDVSGLLVRCPVDFERESRLQTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPJ4</accession>
    <name>A0AAV4PPJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vang-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VANGL1</name>
        <name evidence="9" type="ORF">CEXT_738661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Vang family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004823">
        <property type="protein sequence ID" value="GIX97820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009539">
        <property type="entry name" value="VANGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20886">
        <property type="entry name" value="VANG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06638">
        <property type="entry name" value="Strabismus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX97820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="415" mass="47623" checksum="C88999C0CEB4FB62" modified="2024-11-27" version="1">MSLWTGDIHVGTGINLPRKPNMETESVRSCYSEQSSRSRRSRAHSTHGGSNHHGNRSRPKHLHRTPKSDRSHNSTLASKCGNGNDSRTEEFIEVQILSQDDNWGDNTTAITGNTSDHSGSLDDISKLSRDYETMMIILPKVEALDWKVQKCGPECDGLLISLSFKLLILLFGSWALFFRRPKVTLPRIFIYRAIVLALMIVFTFAYWLFYGVRIIEKRHDDYHSIVLFAVSLVDTLLFIHYLAVILIEIRQLNTQYFVKVVRSPDGESHCYTIGQLSIQRAAALILEFYYRDFSIYNPYLETIPRKSRKMAPGFKMYDVDNVPNSPMNCTNRSVVGSDIHRRDSSHNERFYEEHEYERRVRKRKARLVSAAEESFTHIKRLQDEQGPAIPMDPSEAAQAIFPSMAKSSSKIFAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTB4</accession>
    <name>A0AAV4PTB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_197821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005043">
        <property type="protein sequence ID" value="GIX99396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11541" checksum="E1AB1995B28841FA" modified="2024-11-27" version="1">MEDIIVHHKAMHDKANVITTNTLQIIFIRIIKRNHHLYPPNRKKTKSVFKQTSSTSFSNQITTKLSTDMVWLPLHYVHTVMIQNCELANYHLISVQAIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PU64</accession>
    <name>A0AAV4PU64_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Microtubule-associated tumor suppressor candidate 2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_777421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005099">
        <property type="protein sequence ID" value="GIX99803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PU64"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051293">
        <property type="entry name" value="MTUS1/CCDC69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24200">
        <property type="entry name" value="TOUCAN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24200:SF11">
        <property type="entry name" value="TOUCAN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="430"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="534"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="580"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="626"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="175"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="534"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX99803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="646" mass="73177" checksum="34D483B87F7CFA76" modified="2024-11-27" version="1">MDVAEQQGGAGVLQRTTGVKPARPTAWLSKAELTQEIQRLGNLCEARTKELNRLKMETKHVTVGFDAFASLFKYMVEDLNALSMPVLSEDLKKTLKQLELAKQDLAYYEREVEEMKAHHCQELNDLSNKLFEVFHGEVTELSAKHQEEMNRLQSDHQKEIESLSATFDATSADTLAKQEAVVAQLQQELISQREELQLLQEREIADLEQKHAQSTRTLQEHAEQLQKKCAELRQHSLGMEDAMRKDTDTKLQWVTSRKVDLEKEVESLKAVLEMKNKELHTLRVQNLEMEKQMEDLPLAREKIKMLQARAEDLEALMEEKTKLERRLSTENQQIRDTYERESKVNKRLSMENEELQWRIRQAEQSFLSGSFTDVAEYPEDVENGSLSPAKSPAPQTMSRSVFFTYMDREDQASSPRAQYKKITPGFAASYKTSPCKSSAPSPRRASEPPQPQATPRKVSKGGSLKQKGAHKRQRSGSDCGGKHASGEPPDVAFLSVAGSMTSSVSSESSVFGERLLEEHKEQILESLEILREQRSSEVDWCDKGEEVTTPNLESEDMSRSSEFSDPKTYYHMTFNVMKEQDGDLSAPAQATHSTSESSSSPVCDPQMALADPEGACFVKMAHSVDHAVESSEHDKQSKEQDRWRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PVN1</accession>
    <name>A0AAV4PVN1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_606021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005242">
        <property type="protein sequence ID" value="GIY00961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PVN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043405525" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14511" checksum="672620AE4F0ED934" modified="2024-11-27" version="1">MLARLMWASTITFAEGEAGVSVCEQTISVLLSVGTISENVCAAELLIRNQFGGFLPNRCSRFDTPFRSVPNRKYSCLCRNGHDKSAGQKVMLCEKNLSVSNATVKYVSTKWQYLIRLIAFQCRYGINGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q331</accession>
    <name>A0AAV4Q331_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ZP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_114959_1</name>
        <name evidence="3" type="ORF">CEXT_346271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005522">
        <property type="protein sequence ID" value="GIY02931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q331"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560">
        <property type="entry name" value="CYPHER, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560:SF3">
        <property type="entry name" value="ZP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZP" evidence="2">
        <location>
            <begin position="92"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY02931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="300" mass="33906" checksum="9390FD820B05B472" modified="2024-11-27" version="1">MKTVLKILRRWGAANSSENELNPFNSEDNHIPTSGHADPNENELIEQPKPLYPPIPGAGVHPRATAVEQSAPVVLGFQHERDVPRVEYVTADCFSNYMKITIQFNGSFDGLVYSTGYAHDSDCVYINGSGLERYEFSIRLNIDAELLGRPEFDPSSNEVPDRNHFMWNTITVQYNPEIEEDWDEHFQVTCEYGYEFRRTVTFPVVGKNTASPYLVTLSPPQCYMEVRSGFSASGSRLTGPVTVGDPLTLMIHMESDSTEFDVAVSSCYAHNGAKKRLQLIDANGYRFNFNEYFHQVLFCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8J3</accession>
    <name>A0AAV4Q8J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_140811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005863">
        <property type="protein sequence ID" value="GIY05647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY05647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8500" checksum="843742F7DA1B4C14" modified="2024-11-27" version="1">MGFFNGCNKPQTIATLRSISRENQQFCQPNSQNQPLLSICALTVLCLILLPYYNQDARGRTNAGRGRRGRNLCLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA09</accession>
    <name>A0AAV4QA09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_216761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005883">
        <property type="protein sequence ID" value="GIY05851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7906" checksum="7ABC3EB4F226727B" modified="2024-11-27" version="1">METRTRTTINLRQCSVFPDNPELPSFQFARSPGTPSGIGKRERGLREKLEFRNDPLRSGNNGEKTRGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QB85</accession>
    <name>A0AAV4QB85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_121041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006025">
        <property type="protein sequence ID" value="GIY06958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QB85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14398" checksum="1A58C6EDC7D79DFF" modified="2024-11-27" version="1">MDSTASNAPAGHSNKIKLHNYDFNADKIDRLKIIQRNLQHNKVATLQFLKFMEDNNRGTGATQSTAAPNLLHWHAPPSNYNTSINSTHASALFIHISHDNIENDNTSLSMAMRSAPRFHLTMVPDLHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQG1</accession>
    <name>A0AAV4QQG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein beta chain, ciliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DYHC_0</name>
        <name evidence="2" type="ORF">CEXT_586101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006542">
        <property type="protein sequence ID" value="GIY10581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain tail" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="296" mass="34870" checksum="C092EA5EC41501A9" modified="2024-11-27" version="1">MKDLLSKFENYILEKWKVQLDELDEKLDQALFLKNQDDQVLLNFDSRISAVAQEIRYLKQIKKDNLLSEKAMNFDRKIPNLLLSQSLLACSVQWYSDLSQNLVEYEKKLISKQWDDLIILLEEGYSKIWTSEGLLSYAEKLYDLTKYVYETVMKAKKNILDVEKLIKRWNDVPIYVRETPSSLIELNDLKTPTYKKQLDLIKLTAGRMNDALKLFKSNPDSAEWKDYILCLESIIKEGLIDAIKCSLIYLQKNTDPNNKKIDPFYKIHMLLQQDIIFQPPLKEQDEQSLLIILNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1M0</accession>
    <name>A0AAV4R1M0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Interleukin enhancer-binding factor 2 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ilf2</name>
        <name evidence="6" type="ORF">CEXT_140901</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007346">
        <property type="protein sequence ID" value="GIY16208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1M0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006561">
        <property type="entry name" value="DZF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049401">
        <property type="entry name" value="DZF_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052134">
        <property type="entry name" value="ILF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46447">
        <property type="entry name" value="INTERLEUKIN ENHANCER-BINDING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46447:SF1">
        <property type="entry name" value="INTERLEUKIN ENHANCER-BINDING FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07528">
        <property type="entry name" value="DZF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50152">
        <property type="entry name" value="25A_SYNTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51703">
        <property type="entry name" value="DZF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="DZF" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY16208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8610" checksum="604B9C5E08186266" modified="2024-11-27" version="1" fragment="single">MMIGNAVADIVTILKTLPTVEAVQALGNKVLEELKVTDPNEVLALVMIEGGFELSSPEASVKCLITTVPQNLRKLDPELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3P9</accession>
    <name>A0AAV4R3P9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VWFC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_182445_1</name>
        <name evidence="6" type="ORF">CEXT_203431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007341">
        <property type="protein sequence ID" value="GIY16189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3P9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.200.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052424">
        <property type="entry name" value="Kielin_Chordin-BMP_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46698">
        <property type="entry name" value="CROSSVEINLESS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46698:SF3">
        <property type="entry name" value="TENECTIN ISOFORM 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57603">
        <property type="entry name" value="FnI-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50184">
        <property type="entry name" value="VWFC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="VWFC" evidence="5">
        <location>
            <begin position="121"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="464"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="658"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="666"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY16189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="681" mass="75609" checksum="2FC034037A18A1FF" modified="2024-11-27" version="1">MYNVNLYPSALAVEANVPENRVRFCEHLWEEEGEQRKTRILADFYSWRENEARRTNICLSVGLRSSTDLDGTLHLLQHRLPPLLGYPCLSQSFDSRGIISGRAYKKEVGYGRPVLAMANSPRCTFNGKPVEDGKTVSSPEPCLNCTCSKGILLCYLHTCNSIAPTPGCQIVKKPDTCCPQLECDGMLTYHDFRTERTSEPSNKLRFRQEDSFFGLIGLDTRTDRSSVDTYTTRRPSVKGHKPNFSSFLKGLSSQKRSDVYGQSAYEQEEDIEDDDNSADQNNSSGYCYSRGYKYAEGMAMLSPTKCEYCYCIGGQQMCVRPKCHLNIEGCVPRYQSGYTCCPSHYNCEIASGASVLGIEEKDNADSENKNNLKNKVASCNVEGYDFDVGVAVPSNGHCQTCYCTQVGVVCRRLECSPSISGCTPVIPEGHCCPTQYKCDQKHVNNSHVPVVPHSTDNYDVTVISSLDPEGTSSQSSRTEISDLYTETAEHSPTTYAEDSETATETSSEKQKITVELPSESDLESISVIPEENIAVLVLTTDKEDESIATSAEITSHTSTREDITTKLVPTTVLNAKRKSKPTKLSTVNGKIRNSTRFTTLNAATDPLTITTNREETTQGNTDSVGTEKDIYAYDYEEYEENASPDISETFSPFSDYMTPSEETLLGESSQERSQFQIKTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6I8</accession>
    <name>A0AAV4R6I8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sdr16c5</name>
        <name evidence="3" type="ORF">CEXT_396791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007318">
        <property type="protein sequence ID" value="GIY16007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY16007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16385" checksum="9AB72B8D878205B9" modified="2024-11-27" version="1">MEKNNHGHIVGISSCAGLVGHVNQIDYSASKHGVVGLMEALSEELRLKKSNVKLTTICPLTVNTGMNQNPITRCSWMMPIVGVEDAAHQIVDAIKRDDFIVTLPKRIRFSLSLARILPHQVLSEFLDFTDYCRVKNSDILPKKENDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDR6</accession>
    <name>A0AAV4RDR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_332301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007839">
        <property type="protein sequence ID" value="GIY20098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9167" checksum="CBB7D289143BCEBF" modified="2024-11-27" version="1">MRTELMLGSQRQDSSMSSKVKNAMSFNFTQRPLRVKEAGNGLKQRALITSYCMNAPTSAQTWANANSGGGYASRYETKLLSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFP4</accession>
    <name>A0AAV4RFP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_357011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007722">
        <property type="protein sequence ID" value="GIY19151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12419" checksum="4452A3E019FDA41C" modified="2024-11-27" version="1">MAVDEAEGEDRKSGLGLVDGGDAKGARLPLQGAAQEEADRESGGEEGAQDEKGPVALQVVEAYAREHAAQAGTCPKKKEELIKTKNGNDMTEWIRFVLKKYVLQNTLGMNYITLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRY0</accession>
    <name>A0AAV4RRY0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isocitrate dehydrogenase [NAD] subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">idhb-1</name>
        <name evidence="8" type="ORF">CEXT_753031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008486">
        <property type="protein sequence ID" value="GIY25073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000001">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="7">
        <location>
            <begin position="53"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY25073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="385" mass="42584" checksum="E52199F91333F267" modified="2024-11-27" version="1">MAARKFVFDLTKGISNLNKIKPNVAARHIRSLYWSPVYNEEQAKNLHPQNRVKCTLIPGDGVGPELCQSVKDVFQAISVPVDFEELFLSEVHQSMSVSVEEVIQSLQKNGVALKGTLQSPFSTHTGELQTLNMKLRKDLDLFANVVHVRTFPGVKTRHSNLDFVIIRESTEGEYSALEHESIPGVIECLKIVTKERSQKIAKFAFDYATKRGRKRVTAVHKANIMKLGDGLFLRSCEEVSKNYPQIEFSNMIIDNTCMQLVAHPEQFDVMVMPNLYGNIIDNLAAGLVGGAGLVPGASYSSDCVIHEPGARHTFGSGVGKNIANPTAMLFCAVGMLRHVNLVYYANLIAEAVENVLKEGKVRTRDLGGYSSTTDFTQAVIEHLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY78</accession>
    <name>A0AAV4RY78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_522151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008723">
        <property type="protein sequence ID" value="GIY26700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097196">
        <property type="term" value="C:Shu complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28498">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28498:SF1">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10911" checksum="0E941437609EAF5B" modified="2024-11-27" version="1">MNSITAETFTEIVDTIRTELSFLFDFTAVQALDLVDHRCVMLVNSQVVESYINFEKDQLMCKHKLAAILSTAMGLCKEVQYADETVTLMLVGENNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SAG2</accession>
    <name>A0AAV4SAG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carnitine O-palmitoyltransferase 1, liver isoform</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CPT1A</name>
        <name evidence="3" type="ORF">CEXT_549821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009301">
        <property type="protein sequence ID" value="GIY30964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SAG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004095">
        <property type="term" value="F:carnitine O-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF112">
        <property type="entry name" value="CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY30964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17406" checksum="2F14C428C0C2053E" modified="2024-11-27" version="1">MVQNDVDITTKRALLQRAATKHQNLYRDAMNGKGIDRHLFALYVACKGLGYENEFLHKIITRPWTLSTSQTPHTQMTSLPDANLHIFDDKLCTGGGFGPVSDDGYGFSYIFPSDHRFFFHVSSKHSCAQTSSKRFVQLFCESMEEMVSLFNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE18</accession>
    <name>A0AAV4SE18_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_325971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009175">
        <property type="protein sequence ID" value="GIY30138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002116">
        <property type="term" value="C:semaphorin receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017154">
        <property type="term" value="F:semaphorin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030334">
        <property type="term" value="P:regulation of cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031148">
        <property type="entry name" value="Plexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22625">
        <property type="entry name" value="PLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22625:SF70">
        <property type="entry name" value="PLEXIN A, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="66"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY30138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="21721" checksum="E05B01C641514FA3" modified="2024-11-27" version="1">MYTIVDGQEYNSSCIVDTATEMKCKSPRVPAEKLDFSSDDQDAHPLELEYDPIYYPFSEKNGIKYYKSDYLTINGMNLDRASQETDVVVRIGTSYCNVTSLSRSQLTCRPPTTQPPARDANGKPDVNKIPEVVVEVGDHLKFTIGKLSYEVPSSQDATLTKPVIIGVITGACILVVIVIIILIAYRRKSTESSRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJI0</accession>
    <name>A0AAV4SJI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_16118</name>
        <name evidence="1" type="ORF">CEXT_273701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009500">
        <property type="protein sequence ID" value="GIY32387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12036" checksum="57315062F0F54EC5" modified="2024-11-27" version="1">MQMTISAVLRGISSDLKYPKSTVAYVIKKWKVSGDCRNVPRVGRPTKLGEKETDECSPEIRKNRTQPMALIHEEFQQASGSIVSMNTIRKEAHLRGFHGRAAAHKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMH4</accession>
    <name>A0AAV4SMH4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Lipf</name>
        <name evidence="10" type="ORF">CEXT_492031</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009740">
        <property type="protein sequence ID" value="GIY34179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000021">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="9">
        <location>
            <begin position="38"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY34179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="45440" checksum="936C8273E4C85117" modified="2024-11-27" version="1">MVNDHEAACTFSGSTAPNFLRKSIYNLFRGYGVQFCPTSQLISSKGYPVEEYTVQTADGYLLGVQRIPHGRNGPRNFHGKQEVVFLQHGLLSAASDWVINMPNESLGYILADLGYDVWLGNTRGNTYSRRHIKLTPKMKEFWDYSFAEMAEYDHPAMIDFILNKTGQEKLSYIGHSQGTTSPFAMLSDKTEYNDKLKIFIALGPVTTCGYITSPIRYLAPFTKEIDFLASLIGIDEFLPNGPFMKFLSEYVCDEPIRWICSDIVFAMFGVDLPELNETRMGVYAAHTPAGSSAKSVAHYGQLVESGKFNKYDYGKKENLVRYGQETPPEYDLTKITTPVALMWGLNDDLADPVDVGIMIPKLKSLVDNYQVPLPEFNHGDFVLAIHAKTLLYDEILKLLSKYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNI2</accession>
    <name>A0AAV4SNI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_562241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009942">
        <property type="protein sequence ID" value="GIY35655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8057" checksum="62A8DB1F9DAF987B" modified="2024-11-27" version="1">MAKISETILLDEFLTAVSILWFNDSFISSTRIVKESIDDILQGTHNKLPLVLYLAVWHISQMKCLFCQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SS07</accession>
    <name>A0AAV4SS07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_532271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010083">
        <property type="protein sequence ID" value="GIY36739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SS07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10787" checksum="00BCB9A3F21796BD" modified="2024-11-27" version="1">MAKEYSVNRKVFPLSSKRKATRDYFCYRKHESVRERQKAVVNSIAAIPHRRSPRKAKQSKKAPFLKLVSMSLLSAELQSSDGLPAVKANAVIKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSJ2</accession>
    <name>A0AAV4SSJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_127911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010016">
        <property type="protein sequence ID" value="GIY36156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13233" checksum="5BEF1147960A8C57" modified="2024-11-27" version="1">MVCKSVKSELREEDLKVWEETLKVLYLWRLSKIKRITVNKKKKTTPRPPLLHPWRWTHAAYLSDNRRRTVEEGNAFVSEKKARKRRKEGERPAIRLFSKSPGTAPQAYFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYW1</accession>
    <name>A0AAV4SYW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetoacetyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AACS_35</name>
        <name evidence="1" type="ORF">CEXT_664461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010203">
        <property type="protein sequence ID" value="GIY37685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14903" checksum="0C33063A5A020676" modified="2024-11-27" version="1">MDLEKFAKVPVVWKPDDRCGKFMKKFKNIIEDKYNRQFVDYWDFHEWSINHITELWAEIWDFAGVICSEKFEKGILLELSLGISADNAPVIVGVKNGVYGNLEKLITNLYALGYLYHLVDIATEKGVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8N5</accession>
    <name>A0AAV4T8N5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_645021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010766">
        <property type="protein sequence ID" value="GIY41856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24148" checksum="7C2B49A1537DD719" modified="2024-11-27" version="1">MGLRRTSDIKLARCDLFEMPPPHADFMSSGDDSYKFGWAEGKTSFIKKLACRWIDMPRCGQTCPNKCFDGLHSTFWVNNSCLVQYRFLIVLKNFVALSLVRGLFSAVTGERRRLRMGWKGLCTSFTEIPFDCSFLISHDYLSQVRWSQAERRDPLRFCHQTVAGVPWRTVGGHSSGWWAPTMSVNSVYLGWNCGVHKGVEKRSEVAKYLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBL6</accession>
    <name>A0AAV4TBL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-processing-splicing factor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PRPF8</name>
        <name evidence="3" type="ORF">CEXT_754441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010816">
        <property type="protein sequence ID" value="GIY42207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012591">
        <property type="entry name" value="PRO8NT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRO8NT" evidence="2">
        <location>
            <begin position="83"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY42207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="22271" checksum="B3FD8F2585FB7053" modified="2024-11-27" version="1">MIGHPYVMGMLAQQQAFAAQMAHAQAQMQQQQMQQQQQQQQQLLKQPEVLSEEKLQEKARKWQQVQSKRYAEKRKFGFVDAQKEDMPPEHIRKIIRDHGDMSSRKYRHDKRVYLGALKYMPHAVLKLMENMPMPWEQIRDVKVLYHITGAITFVNEIPWVIEPVYIAQWGTMWIMMRREKERSSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCY3</accession>
    <name>A0AAV4TCY3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RpL19</name>
        <name evidence="7" type="ORF">CEXT_394561</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010922">
        <property type="protein sequence ID" value="GIY43059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY43059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="23534" checksum="235AFD8CD1EE6D5A" modified="2024-11-27" version="1">MSCLRLQKRLAAAVLKCGKRKVWLDPNEMGEIANANSRQNVRKLIKDGLIIRKPVAVHSRARVRKNKEARRKGRHCGPGKRKGTANARMPKKVVWIRRMRVLRRLLKKYREAKKIDRHLYHELYMKAKGNVFKNKRVLMEFIHRKKAEKSRSKMLLDQAEARRQKVREARRRREERQQQKKAELLQAFQKEEEAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQG5</accession>
    <name>A0AAV4TQG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011387">
        <property type="protein sequence ID" value="GIY46218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13457" checksum="81514DCDC53F4245" modified="2024-11-27" version="1">MFRWKSLGTALFQSPSEIQIVQFTPVIYPQLIERKSLFILTPFAADKLNDLPTKTLIIKCEGDFPPFLILKCEGDPYFKQCSKTFKIPDPKCINYEDTGHLVSWKGCLPMLPESTPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSR8</accession>
    <name>A0AAV4TSR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_544761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011527">
        <property type="protein sequence ID" value="GIY47148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8695" checksum="73C9CD6FA1FE36E7" modified="2024-11-27" version="1">MVLKDYATKYEPKVLEVELLEANPDSTHVRLPDGQTGDKHLAPVAESSSTEIEEESNLQDQEEALQEPQYLLPRTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U933</accession>
    <name>A0AAV4U933_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_754991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012483">
        <property type="protein sequence ID" value="GIY54215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U933"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9503" checksum="2EA777FFE1BBB38B" modified="2024-11-27" version="1" fragment="single">VRIPSFPFKPYHSFASITVEHSFDLIEAKAFKTALLRLICYKQSLTSKPWSPLTNPLSEMAVFSSANEPTYKTAMAVCTTRSIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB98</accession>
    <name>A0AAV4UB98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_668361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012603">
        <property type="protein sequence ID" value="GIY55079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11490" checksum="74B423367E3848C0" modified="2024-11-27" version="1">MQNIIKNRVNTILTVSFPSGNAYRLTERIPIRIQRNPNVREFRFESDTGVSHYFQKRGNSMTIRAITINVSTWRKLSWFSPLQHTNAEQLPLEIFPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCP1</accession>
    <name>A0AAV4UCP1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PFU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_587351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012647">
        <property type="protein sequence ID" value="GIY55505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015155">
        <property type="entry name" value="PFU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PFU" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="201" mass="23897" checksum="F87EED340F902F4D" modified="2024-11-27" version="1">MDVEMSLCKEMDQLEVDPDYKKLKKDIEVFMQIDDVNYRMSFNKDDNVYDVAMGFITKNALNPDYLDEIMIFVEKYDYHVDFNVDFNALKEKFLDVTKLVPECQKLSYEDIKEILLLVNVPEDVTYRQFQLLDAVLSWADEIFIEAAVQREIIRSESKFCLRISKHLKTYNTDQNSCVYIKKFTRFIELPHPTVLYSYSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFB9</accession>
    <name>A0AAV4UFB9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_260431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012776">
        <property type="protein sequence ID" value="GIY56517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFB9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15827" checksum="0C6F74E6272D2C7F" modified="2024-11-27" version="1">MSQNELGKRILTNFLKLEHSHCNPLIEIRFKNSTQHNGFIFPGLFGFHPISLPTDLKHEKKPRDLLFFLTTPQVYFVLLFVGSGSLRSRIGVPLKIISSSSVCRLACGSRSLCRIVQPSGAMGWKWNKIGGLFVGRERASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKA9</accession>
    <name>A0AAV4UKA9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrator complex subunit 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">INTS14</name>
        <name evidence="8" type="ORF">CEXT_694301</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Integrator subunit 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013036">
        <property type="protein sequence ID" value="GIY58218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039841">
        <property type="entry name" value="INTS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045814">
        <property type="entry name" value="IntS14_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046471">
        <property type="entry name" value="IntS14_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13532">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13532:SF3">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19435">
        <property type="entry name" value="IntS14_b-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20504">
        <property type="entry name" value="IntS14_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="48"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 14 beta-barrel" evidence="6">
        <location>
            <begin position="259"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 14 C-terminal" evidence="7">
        <location>
            <begin position="449"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00061449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY58218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="553" mass="61702" checksum="44C5B4FC1C3D3304" modified="2024-11-27" version="1">MNLRSNFGAPQLLMIEASVAVEDERQLLHNCEVSHCQNVPKAKNKMPTVIVLDTSLSMHRPVQMPDVPEPFGFRNLAVHGLTYLLDYMNINCKLEFAALITFNSNRETVVPFTRDFESIKSALLQLEYHETSQFAKALEAVQSLVMEEWGAGVPCQVVVVTDGAIGAEIGQLKNDMERHFSVTEKGTEDSTFPLPFPFPCKLHIACLSNLTDPYLKNSLPIYKKIIDINGGGGQLFIPEGAVNFKSIQNMFMKLADLYYKPFHGVLHCGTLTSSVALSPPPEPFCKARDFELVKAEMSTDIVICGFISIGDISSPPSHSRHLILPLQSFKEEIKPPVVKLENSETNEEDSANEDGKQPSFCVLLHGSLRVEGMVAICHLGGDWYGMLYSWADSKKKSNLMLSAFEPGPHVIPWLGNFTHLGPTELAPESDIPTFPIKPSEKRSYAQNCVVWIRQPGLQADIQKILRHARKLPEKTQNFYKELNRLRRAALSFGFHELLEGMATILDRECTLLPGSAHPDAALQLTHCANALRNNSRDYNAPVLPLRTKFSMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQJ4</accession>
    <name>A0AAV4UQJ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Methionine aminopeptidase 2</fullName>
            <shortName evidence="11">MAP 2</shortName>
            <shortName evidence="11">MetAP 2</shortName>
            <ecNumber evidence="11">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">METAP2</name>
        <name evidence="15" type="ORF">CEXT_701551</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11 12">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="11"/>
    <dbReference type="EMBL" id="BPLR01013270">
        <property type="protein sequence ID" value="GIY60043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000106">
        <property type="entry name" value="Methionine aminopeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11 12" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="14">
        <location>
            <begin position="174"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY60043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="484" mass="54234" checksum="F597A6235397932A" modified="2024-11-27" version="1">MAAVVQDHNAKVEEDSNEIRDDPNDVDDAEDELSAKDPAQKKKKRKRKKKAATHQDGVNDTSEDVEIVTEKLQHQVLDGEVNNRDADGEEEGTKEAGEITKKKKKKKGKGGGTAPKQTNPPSIPIKALFPDGNFPVGEEVEYSFGNDSRTAKNRFTSEEMKAVEQETMEHIYKDIRQAAEAHRQTRQYMRNYIKPGMTMIEICEELEKTARALISENGLEAGLAFPTGCSLNNCAAHYTPNAGDTTVLTYDDVCKIDFGTHVNGRIIDCAFTLTYNPKFDKLLEAVREATNTGIKEAGIDVRLCDIGEAIQEVMESYEVELNGKTYPVKSIRNLNGHLIGQYRIHAGKTVPIVKGGEQTKMEEGEFYAIETFGSTGKGYVHDDMEVSHYMKNYEAGRIPLRLNRSKQLLNTINQSFGTLAFCRRWLDRLGQSKYLMALKDLCDKGIIDPYPPLSDIKGCYTAQFEHTILLRPSCKEVISRGEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQU3</accession>
    <name>A0AAV4UQU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat-containing protein 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Wdr43</name>
        <name evidence="7" type="ORF">CEXT_562491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013296">
        <property type="protein sequence ID" value="GIY60235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="413"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY60235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="600" mass="68379" checksum="B6186342EFF8FCB0" modified="2024-11-27" version="1">MNIRKKSNFSVNGEYFALSNEDGSLKIFETSTNTVKRECILNSSTNYRCSSLIWGPTKHEVNLAERKKIDDKSFTNAQYLIIGTEGGQILLYDFIEEKFYNHFITSHSDAVNDLFWHSSSNRLFSCSTDKSIGVWDITSTKNTKVKLSVALFDFCIEFLSNKWEADNEPLNSICVIDNENLLAASTSITWWNIKEQTIIKKFDGHNSEIFALLPVISTDVSSNSYFLSAAVGDSKINAWHLNVENSKHSVASFNIQGDLESLDPMYLSAIIKEGPLLLFKHVLNGRPKKNLEPQKTLHILSNTADSTKPSITPIIASRFSEDLTFCTIAYGSYENPIFEKMKIDDFPKTLTLCREKPLLSEETATLISEVKMYNKLGEYISANGTLILNSKLSTPKKKKQKDPDLNTPCKEIEESVSENENIQSPIHRREPSSSPNVKKTRKSKQSVSPERNVESFTEESFSNPSNVIDNLSRCLQTEDKTLLNMVLKCDDEELIESSVKKIPENKLKFILQGIYNIVTNQQNRLYAKKWLKKILSIHLRHIMQCEDLKETIDLIENYFNQQRFDEKGKLLLQLESVLSLLIQNEDSDTIDSDTDKEMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4US35</accession>
    <name>A0AAV4US35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_348291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013335">
        <property type="protein sequence ID" value="GIY60524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4US35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15195" checksum="9FDEC2414AA5F0BC" modified="2024-11-27" version="1">MGLFIETERDNIYERIPHRSATKLVCREQNTAEDVACLGFLENGRRNISYFLLVFSNSGASVFVLRHFRVSETAGRSSELIHMESLLQMLKMSGIFFFFISLRYNSLNLKKDLWGICLREKKEEEILEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UT36</accession>
    <name>A0AAV4UT36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_117141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013398">
        <property type="protein sequence ID" value="GIY60913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UT36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11886" checksum="175FFA822F66CE5F" modified="2024-11-27" version="1">MNSTRRRETDHIFSSMPFKVEVSLPACRSGRVSFQGDNFLHILRLLRLPHKQFNVTDSKNVYATARIRILKIGTKAPYRQELSMRSRKVPSKETRLQNVRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTR9</accession>
    <name>A0AAV4UTR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Probable ATP-dependent RNA helicase DDX17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DDX17</name>
        <name evidence="3" type="ORF">CEXT_123101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013390">
        <property type="protein sequence ID" value="GIY60889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UTR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY60889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20546" checksum="DE75C1F303E3CFF6" modified="2024-11-27" version="1">MGSLHCVFMEIKLSKNEIGFWGQFRDGRHPILVATDVAARGLDVDDVKFVINVDFPNCSEDYIHRIGRTARSNKTGTAYTFFTFGNMKQAKDLVDVLQEANQTINPKLMDLVEMSRTFGGGRNNNRRWGAKSFGNRKFDENRKNGSYNRSRGGGGGKFQSNGGRFGNDSSKNNSFKGTHKIFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VB14</accession>
    <name>A0AAV4VB14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_49601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014215">
        <property type="protein sequence ID" value="GIY67228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VB14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="21187" checksum="DDEC0EA69B1C80EC" modified="2024-11-27" version="1">MEDEALWPFVKQSDSSTLNQINQPLNQINNSRQQSLFSGIHQITDCEETTAAEMASQYGDTNPNSYIPSDYETEPSDYLFPEMRYIQEIDLMSTHLQLPPEVSNVFNNQNPQNYESSNVEHAGSTPLSAATRCFSPGFQQIFDRRNPISDTTDPSASSVNCEKISKDKSLGGTACTFKDLDAPQNEDSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCC1</accession>
    <name>A0AAV4VCC1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_565701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014280">
        <property type="protein sequence ID" value="GIY67781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043327145" description="Secreted protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13920" checksum="EB0BEA486CEA489F" modified="2024-11-27" version="1">MMRKKYTTRLECAFLVVIALPAQLTSATVKCFEFETQTLAFLSFFFPLFVERVRRRISAKKAILQRTLGIFTLRYFSKDLLGRHRVLFTGAIGQRVAKCCRTLAKRTQCQRLKKEYTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJV4</accession>
    <name>A0AAV4VJV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_457431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014631">
        <property type="protein sequence ID" value="GIY70156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7928" checksum="CE99513364B778DD" modified="2024-11-27" version="1">MIHQTPETIRTIDLDHLSTCPMNPASRGRHALPEEWAIEDYLEKTIFSRESGHDTKTCRNLKGKGCARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VP70</accession>
    <name>A0AAV4VP70_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="11">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HCCS</name>
        <name evidence="13" type="ORF">CEXT_548841</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:22650"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="11"/>
    <dbReference type="EMBL" id="BPLR01014886">
        <property type="protein sequence ID" value="GIY72027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VP70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF0">
        <property type="entry name" value="HOLOCYTOCHROME C-TYPE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0349">Heme</keyword>
    <keyword evidence="6 11" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="47"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY72027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="275" mass="31808" checksum="511A68843EB7F02D" modified="2024-11-27" version="1">MQERTLAAFLTPELLKVKMGTVSSSVGASTASTPILNESLSKHIQEHSVKPNSQSECPYKHNQEQTDTSKQRCPIQRDDDVNPNNMMPPMNQNPSPDQPFPLPKQRQVSSIPKAGTENEYWIYPSSQMFWNAMLRKGWKWKDSDISPNDMDHIIRIHNVNNEVAWREVLKWEALHADECTNPKLLKFGGKATEYSPRARIRSFLGYELPFDRHDWILDRCGKQVRYVIDYYDSGSVNVQNGRFATLDVRPALDSFEALCDRTKVMFWRWTSKEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSJ5</accession>
    <name>A0AAV4VSJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_107361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015017">
        <property type="protein sequence ID" value="GIY72988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY72988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9226" checksum="D664D9A3BD09BB0A" modified="2024-11-27" version="1">MGASLNEKFTIGLGYIFCRSGTKLSLALGEWENCFHQPLPHPPSETTASPLGVYQHSRSQVSGRFVSSSQTQEGEAEKNPLTCTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSR5</accession>
    <name>A0AAV4VSR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_40411_1</name>
        <name evidence="2" type="ORF">CEXT_701351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015081">
        <property type="protein sequence ID" value="GIY73447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11253" checksum="8C2CE75A8C01EF82" modified="2024-11-27" version="1">MRNRELMMMQLCLDEFVPSPQDIEIIDPDGCDTPRRDTSMDMEVYVSNCPITVRVQVEPRHLASMESDGLSDSDISDPGEIARISRRDMDFPEQHKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSZ0</accession>
    <name>A0AAV4VSZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015029">
        <property type="protein sequence ID" value="GIY73059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10458" checksum="8F9962CE64B2DAB7" modified="2024-11-27" version="1">MLERLSYGIGIQVRTTGRHKGELTGRHKGATAPTGRGNLDLFQTFHLKPALDNLTRIMLRIQRRRTIQDGEGGIGEVGNVLLYLPTNKLLWSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUB0</accession>
    <name>A0AAV4VUB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015029">
        <property type="protein sequence ID" value="GIY73068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10116" checksum="BE35F460FECCCBDB" modified="2024-11-27" version="1">MPSRTLLLPSSCSKGELHLSYKNKMFAYPKWSKQFVIRVHFRPLSLFNYRRQTRTDEAKMALSLHVRRPFSGSLAETKESRLKNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0E5</accession>
    <name>A0AAV4W0E5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_423341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015344">
        <property type="protein sequence ID" value="GIY75466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12197" checksum="8FEDE8AFF59BDF65" modified="2024-11-27" version="1">MDDLQRKSPFNVWEENQFGKKYILVNIIILKRQYLLHHSKPIKTTLRCILNTDNTMKKRALGGGFITRRKSPPRFGMEDCFNTLLVGGKKISRIQGRCFLWCKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3N8</accession>
    <name>A0AAV4W3N8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prefoldin subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PFDN1</name>
        <name evidence="4" type="ORF">CEXT_724841</name>
        <name evidence="5" type="ORF">CEXT_724842</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015609">
        <property type="protein sequence ID" value="GIY77347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01015609">
        <property type="protein sequence ID" value="GIY77348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3N8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY77347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY77348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7734" checksum="D0A83E4093E6B392" modified="2024-11-27" version="1">MTAKGVDLELKKAFQELQAKVLDTTQKLKLADLQIDSYNKSIQHANLTQYELKSYPGDINMYNGIGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W666</accession>
    <name>A0AAV4W666_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_798831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015579">
        <property type="protein sequence ID" value="GIY77088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W666"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10607" checksum="A44392416614EC1C" modified="2024-11-27" version="1">MPFKRKGEGMSAEYIRYRHGRMQHIGRKTLRWNKNFRFIPELSGGKKWGKVTEGGTLCKKEGRERERRKYVPSEFSNNAVDPLLSHLSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6M1</accession>
    <name>A0AAV4W6M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_161031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015755">
        <property type="protein sequence ID" value="GIY78411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11147" checksum="B91F9CA43BA55A79" modified="2024-11-27" version="1">MPHRKIPKTFENFAAKCLCSLLLPLKDLLKQDTFEFTKEILGKDRRGGGVEKKNGKVKMVSPKSEGPSGGNPRVIEIVIHGRWTAERFVEGGENIYLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8B4</accession>
    <name>A0AAV4W8B4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_570211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015759">
        <property type="protein sequence ID" value="GIY78459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8B4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12410" checksum="D294AA5AF68E0FCA" modified="2024-11-27" version="1">MELVERKISTHLQKVRLIGSCPKFRCNMHSLSTENLGNPSATSQSASNNLKREPDHDNDGFQLPSKRNTVKPTFPNSVPTTNKFTQLESLPIPDSFTPQAPRIPPPSWSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8Q1</accession>
    <name>A0AAV4W8Q1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_622121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015707">
        <property type="protein sequence ID" value="GIY78003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8Q1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10967" checksum="81D63ECB359A1027" modified="2024-11-27" version="1">MVSDSFVGLGHQLFNSVPFVPGYRCPPRPYGRMDSDLEPLKRSRWRPEWRGRKKKVLSTSRILQLLVVSQSALVMVWFFPSLRLGTKFREGLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEV2</accession>
    <name>A0AAV4WEV2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pre-C2HC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_620701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016005">
        <property type="protein sequence ID" value="GIY80384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006579">
        <property type="entry name" value="Pre_C2HC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07530">
        <property type="entry name" value="PRE_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-C2HC" evidence="1">
        <location>
            <begin position="17"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="24123" checksum="185BB756ED670199" modified="2024-11-27" version="1">MSVKVVIRELPANIDTKDIEVQLTHAGLVVHKILKLSKFPTKGPMPLFYVQMKQNGNSETAYKFTEMLGGMVFGLNLLQPCSKKEDSNILKPNGLDTIDKFSQDNLAIAYTDGTPDKFFNKGGAGIFFLLPNGSKYHLNVNTDLIDSNFTSELIAIKEVVALYLNDPNISGLTDGVQHTNTRPRHVFISFFADAFFCRLAKAKPTIACESAIGTCSAIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFG5</accession>
    <name>A0AAV4WFG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_65021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016114">
        <property type="protein sequence ID" value="GIY81377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="22751" checksum="28F2A58EB7CECB52" modified="2024-11-27" version="1">MGAGNTMSPPTLIIARHTHTHTHRKKNKKRKKKKEKESLTSLLKIREQSSLLFSIDFGHKGNFFFPLLFLYTVPFEKVNARNLQSQSKHHPVVTDRMRLWKSVGNRSREDVRASYHILFTHMSASFSEGHRFRNPHEFYIHPYQPLSIRAQLCSSQLKNSHQIRQQHKQRRHSCFIKRPVCVILMDACSLTPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIU3</accession>
    <name>A0AAV4WIU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein dachsous</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ds</name>
        <name evidence="11" type="ORF">CEXT_66341</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016134">
        <property type="protein sequence ID" value="GIY81483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000181">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000081">
        <property type="entry name" value="protocadherin Fat 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000279">
        <property type="entry name" value="Protocadherin-16, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026">
        <property type="entry name" value="FAT ATYPICAL CADHERIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24026:SF126">
        <property type="entry name" value="PROTOCADHERIN FAT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="28"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="134"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="265"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="427"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="530"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY81483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="607" mass="67064" checksum="71C599EFDC33819E" modified="2024-11-27" version="1">MTKEHLSARTSSSCRSRCWTSTTTSPCSPSSLSFKVKEGVGVGQEVGVIQAIDEDGGENGRVMYSIVGGNLYDIFDIVRSTGSLYTIAEVDFEKASEYHLQVKAVDNSAVNPHSSVISVKIEVEDVNDCAPVFKNDPILFSIPENTPQGTLVWNFSATDLDSGVNGQVIYFLSQQSPASVFQIDRKTGALTLTEALDYEHFQEYTIVVTASDQARDTKQRLSTSVTCKIIVEDKNDNAPVFKTRSKINVLESEPVSYPVLHVIALDEDSRDNGLLSVAKSMDREEVSHYELNITASDHGRPPRASHQILHVYVEDVNDNPPRFKQRLYQANVSEAAPKGTFVLKVDALDIDLEWPVVLFYSERRCREPLHHQRSDGRDPHGISVGSRAPSLVLRDRVRAGRSLSLSPRHTAVRIDLLDVNDHAPEFGDSCYTLRVPENSDLSVIHTLVATDRDTNANAEVTYTITDGNTGNKFSIDLHTGQLSSRPLDREQVQQYRLVVSAHDQGEPPLAGMCNVTVIVLDQNDNDPQFEHSEYSATIAEDAASNTTVLVVRAQDPDDGVNSQITYSLGNETRALFRIDSATGSSLQQATEIKEVHQAIIDDFHHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQM3</accession>
    <name>A0AAV4WQM3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">YLPM1-like spectrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">YLPM1_1</name>
        <name evidence="4" type="ORF">CEXT_676251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016531">
        <property type="protein sequence ID" value="GIY84593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058903">
        <property type="entry name" value="Spectrin_YLPM1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26583">
        <property type="entry name" value="Spectrin_YLPM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YLPM1-like spectrin repeat" evidence="3">
        <location>
            <begin position="86"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="707"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="527"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY84593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="726" mass="81419" checksum="6FD652FAF7E28334" modified="2024-11-27" version="1">MLVVGGPRQNYLGLTPKDNAESEKLKQLKEQAEKWKSLQQPTAAATTTWPYPAGVSVTAPSVTTTGNSLKSNENTNAAQPNIEQQGVLDPEEEQFEQQFRDWEKQFEAWKEQNINHPDKEAFAQYEKQWHEWRASLLQKKEEMLKEKAARLAQQQQSGNAVVTTAASLNTSTGPTSTTASVADAVANANLYYQQAQYMYMQPYVYPGAMPVAPPAVPQQFPYGGQAAPGPSDGFSGPPPMGGNGGPPMNMSNSNMNTRDMKGFEQDNEQFKYGPGGENYPHPEGSYGNFNDYGNSNMYPPDMAQDPYQRDVNFGRGRARGRGRGRGRGRGRWSEPNEKEGPLLPNMRTPGPALLDPPDFAEGPGKFRDGPGDFREGPGGPRNYPQGPADFLAGGPGHFPRGPPRDYPPGPGEFEGPQEGPEEFTSGPNSRPPYEYPHENFSGDYPDGPENHSRQRRNYTPDERYPFRDGQPPPRDGKPPLLPRDGQPPLIHDGQPAPFEGQQPPLLRDRPPGQFPPGEYDEQYPPRPYDDRFPDSERFPPHGPKDDPFMDRKYDDYPPMEDDHFGPPPPFGEDFPPFDEHFPPGRGRFPPRGRRFPPGHRGDFDRFGPPNFPPGMRDDGPPYGHTDERFPPFPGDGPPPRMPPPGRGRPPFSPRFPPEDPFFREGGPPSMRFKSIDYTHRSSADFDPHYEYESEFQDDVGQFRAVPMKRNKRPAPRKMPVEKKIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWK5</accession>
    <name>A0AAV4WWK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_212521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016779">
        <property type="protein sequence ID" value="GIY86315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8738" checksum="4220F0AD485CF05B" modified="2024-11-27" version="1">MDDTTPECLDLKGCLPIIKEPGKRTGFILPVKTRREICPDYLPVYLPVISSTGENPYGGNYCLPLTYYRSIKKSTAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3X8</accession>
    <name>A0AAV4X3X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017115">
        <property type="protein sequence ID" value="GIY88880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8153" checksum="7A089B9FD906D7ED" modified="2024-11-27" version="1">MSVRPESSFGNFDHTEATISVVLLKLRKAVTLSVPSAHSCTCPPVANVWLCDHFRIMIRGKRSKAILLAERRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5C6</accession>
    <name>A0AAV4X5C6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_598201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017178">
        <property type="protein sequence ID" value="GIY89190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5C6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10019" checksum="3D731B9529C2B134" modified="2024-11-27" version="1">MVSRFVAFMELFMVYGEQVRGIYGTIHVYVEQVLGIYGTIHGICLSSGICRAVIYGVRKCAELFMAYAEQFVAFVELFRAYVENLGACV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAY2</accession>
    <name>A0AAV4XAY2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein E</fullName>
            <shortName evidence="9">snRNP-E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sm protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SNRPE</name>
        <name evidence="11" type="ORF">CEXT_192491</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000004">
        <property type="protein sequence ID" value="GIY91355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01718">
        <property type="entry name" value="Sm_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027078">
        <property type="entry name" value="snRNP-E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11193">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY91355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="11002" checksum="F1AA042849EBF985" modified="2024-11-27" version="1">MAYITQKVRKYNLQPINVIFRYLLNKSRIQVWLYDVNFRIEGTLLGFDEHFNLVLYDAEKVLKKSKARMMLGRILLKAERILLIRNIDGTSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBY7</accession>
    <name>A0AAV4XBY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_92591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017568">
        <property type="protein sequence ID" value="GIY92637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11822" checksum="EAA6A451F4031685" modified="2024-11-27" version="1">MNSKIIPPPYKTISFFELSHSWCRNTPSIHFRQSPRQAHKDNSSPTHIYVHWPIFRTISMEGKMKSIFNIHQLCCNTLQPKFFSPIATGRALRLLGMHRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC17</accession>
    <name>A0AAV4XC17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_91501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017570">
        <property type="protein sequence ID" value="GIY92650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15195" checksum="324BB79617ED744E" modified="2024-11-27" version="1">MAIQNLKPLTALFCYQFKKKKRGGRDRGVQTSEPETNFSENLSRNETASQPSLPKCPNHSRFRERITAGGREIKRDLPDRPVCLGIRILIGISDRPFRYACGPLICFRATSPILKVHSKAWGGGGWKNKPFRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFZ9</accession>
    <name>A0AAV4XFZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CD109 antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Cd109</name>
        <name evidence="2" type="ORF">CEXT_246101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017749">
        <property type="protein sequence ID" value="GIY94146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.690">
        <property type="entry name" value="Alpha-macroglobulin, receptor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009048">
        <property type="entry name" value="A-macroglobulin_rcpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036595">
        <property type="entry name" value="A-macroglobulin_rcpt-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF172">
        <property type="entry name" value="LD23292P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07677">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01361">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49410">
        <property type="entry name" value="Alpha-macroglobulin receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-macroglobulin receptor-binding" evidence="1">
        <location>
            <begin position="262"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="388" mass="43613" checksum="EB916515EA7E58A2" modified="2024-11-27" version="1">MTSICESLQELGGEVSRAKTAARRYLEKMLHSTRDSKDPHEIAVVSYALTLAGSVDGEAAFNALDAKMRDTAGLRYWGREPVPPPLIRIEGNRPHMLPRLPVSHDARNVETTAYALLTHIRRQAVIQAEIVRWLQAQRSTNHGWASTQDTLVALQSLMEYNIQSRLRDVMDVTLTVEVPSLPGYSRQIHIDDVNFSEMHTVEIPRAFGTVVVKAQGSGLALVQLSVDYNVEWRHLMMPPPCPPSTLISGLNTRAGTTPGSLSAPVRAGPSCQRAEPVAWRYWREGGIVFYFEHLDVSPICVTFDAQRWYPVANMTRFLSAKVYDYYAPERYNETIVEMFNLFVMNICQVCGSYQCPYCPVFSSAPGLPSTFQIVLLLLLLLYTFRQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHQ2</accession>
    <name>A0AAV4XHQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_545711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000271">
        <property type="protein sequence ID" value="GIY93481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12284" checksum="468A8B704BC52190" modified="2024-11-27" version="1">MKKVFEYKELQWTIVGDNQPITQENAKLTREDIFTLALYNFFMKPSAMAKSSINAKECYQCKTCEKGFYRKYHISDCLSTLKVKGKRQSKYVYAGVFSSIKVPTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ29</accession>
    <name>A0AAV4XJ29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_363701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017784">
        <property type="protein sequence ID" value="GIY94448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10919" checksum="522C650B7D994866" modified="2024-11-27" version="1" fragment="single">QTRTGVSGRHTETISQPKYINCGPIGHLAAWRGRPLFPKQKPNAATTINSRSIRQQTTNPDGFPKYNLFCCPTALKKYTHHLSFLSRMSNDHPLVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL17</accession>
    <name>A0AAV4XL17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_97841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017903">
        <property type="protein sequence ID" value="GIY95379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10390" checksum="DD2A0F1B2CB70D12" modified="2024-11-27" version="1">MILDINHAISHVTPQRMTPINTWPKKVDKTLVPSTPSSIFFLHTPAAICMRGYFPVGKGLDGKRSLLLSLRIRHPHPLCTDFDLFLSRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNF4</accession>
    <name>A0AAV4XNF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000690">
        <property type="protein sequence ID" value="GIY96681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11841" checksum="40B84F2C9FE35CD5" modified="2024-11-27" version="1">MQTKSNSSAIRNPTKFLGNKLPPIILLHARMETKRSNSGTGQRAEKLSTLIGNGGSVHLREYETLAFHHNAPYSPNAHNNNERAVELQERREQLFRNPSAHCQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSE1</accession>
    <name>A0AAV4XSE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cathepsin K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ctsk</name>
        <name evidence="2" type="ORF">CEXT_559481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000880">
        <property type="protein sequence ID" value="GIY98092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="1">
        <location>
            <begin position="55"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="19356" checksum="A5D222C1CD24C47F" modified="2024-11-27" version="1">MPYVSLFYPSFGIAVFEYSLNTFQQRTMKFLALFALFAVAASRHMLFDQQLNEHWENFKKTFGKQYNGGEEVVRRTIWERRVADIVRHNLQYDLGLHSFRKGINEYSDMEHEEFVRTFNGYRGLVNLKSNATTWVPPSNVRIPDKVDWRDQGLVTPVKNQVRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUG3</accession>
    <name>A0AAV4XUG3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ionotropic glutamate receptor L-glutamate and glycine-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CEXT_59851</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000918">
        <property type="protein sequence ID" value="GIY98379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF38">
        <property type="entry name" value="IONOTROPIC RECEPTOR 100A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="13">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY98379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21730" checksum="AA34A4254C4F5917" modified="2024-11-27" version="1">MHLRVAVAEFIPFLKLRKENGNVIMSGALADAFDLIARRVNFTYTLYRAEGDVWGIKRPNGWTGMLGMVSRNEVDIALGPFTLTYGRWSEFKMSAPLYADNIEILTPVFEWRMALFNMITVFKYEVWILLFFTVILICLAMSVTDKCDNPNSKFQTRICKNLWNVTRTLLQKGEGTNNYNYFALNLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWL3</accession>
    <name>A0AAV4XWL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_189100_1</name>
        <name evidence="2" type="ORF">CEXT_59801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000918">
        <property type="protein sequence ID" value="GIY98369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="432" mass="49506" checksum="1B4DAEC7BBE52BAF" modified="2024-11-27" version="1">MSQTEVSSNMHYGNDSPRILENDGAASTIEVSSNMYYGNDSPKIQDNDGAASTIKWNDPVNQRRKKSGALKNIFDDEFRSSLNIYERDIIQQKYEELSGYLRRESDEFEENLKNQSSYSGRTKDFLDQLYPKYVEKYKRLQRLVSEWKTNREALIEKLTLKSNQLDRNFKISTIIRLVASLIEVSGTVVGLMSEPKSGGSKYALHAASFCGLFGLFATVAEVDQSKRILDEVSEGIEEYHKLLRPIIKLFEETEELDSIVQELFPHGINTDIVRQIQAASEEQADYLKIFKAGLMSNAEKNTNLYENKDFLHCLQLFASSDLASLWWSRIIYRKHPINLDLNKMALQTEFGQLQSIVFQCIPALPLEQQRLTSLPVAGRIMLNLMTFYDSLVDLRKGAKSVHSDKLRKQLKNISDELQLIEDTTNMVKPCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY24</accession>
    <name>A0AAV4XY24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_765571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018327">
        <property type="protein sequence ID" value="GIY98703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9299" checksum="53E5C471548E1DB8" modified="2024-11-27" version="1">MLFDNTQPSKAYRYEGSDPGGISLQAFYDTAPYYRVLSSPFHRSSPLGGKGVSSAISLTKGERGERKRTGWKHPSTLSLLLYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y015</accession>
    <name>A0AAV4Y015_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">tubb4</name>
        <name evidence="14" type="ORF">CEXT_81051</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="11">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001160">
        <property type="protein sequence ID" value="GIZ00498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y015"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000003">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="12">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="13">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIZ00498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="414" mass="46364" checksum="AA416C9BD6A0E37C" modified="2024-11-27" version="1">MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGAYHGDSDLQLERINVYYNEASGGKYVPRGILLDLEPGTMDSVRSGPFGQLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDTVLDVVRKESESCDCLQGFQLAHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVLPSPKVSDTVVEPYNATLSVHQLVENTDETFCIDNEALYDICFRTLKLTTPTYGDLNHLVSVTMSGITTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMCACDPRHGRYLTVATIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNTTAIQEIFKRISEQFTAMFRRKAFLHWYTGEGMDEMELLKLNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3A9</accession>
    <name>A0AAV4Y3A9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_182011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001318">
        <property type="protein sequence ID" value="GIZ01553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3A9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="32258" checksum="419BF77AB284FE24" modified="2024-11-27" version="1">MERRNCEFCNAYITNFEVHSCRNVFNQHRLRNATLPRSGNRAEGTDSRLTQRMNSGALWPTTSQINSPTQQSILPNILQLTHFEETAAAEMSSPYRIAKWNEYIPEVSDCLFANMPQVEENQSETTHLQQPPEMFGQKNPWENQIAENPSASSQMERSGISRTDEMPSHFISDFIQNDIASTSRISQHNETSLGIPILAVENVQHNPMDPIPHTDTTGPIHSNKCPTEFLPKDHPEPQDISGSVARPYSYWKNTSAASTLGKNYINAQNVVNALLSVPTSNVTCLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6N9</accession>
    <name>A0AAV4Y6N9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_484421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018759">
        <property type="protein sequence ID" value="GIZ02120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6N9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043977550" evidence="1">
        <location>
            <begin position="16"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12606" checksum="714038DF4E0D369F" modified="2024-11-27" version="1">MLLLLLLISTGPAGLDHLHESLNIQEVKEVLFGVVIKHPLPVLSLSILLPSVNIRSKNVSRNLQSHQLQADRNLCLFIYLSHQFSVKQNIWKTRGGIYADLQKMSLNLLGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDU1</accession>
    <name>A0AAV4YDU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Solute carrier family 25 member 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">slc25a39</name>
        <name evidence="12" type="ORF">CEXT_393551</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019280">
        <property type="protein sequence ID" value="GIZ05313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="84"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIZ05313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="21524" checksum="5B809E6E7AB95B52" modified="2024-11-27" version="1">MLLASEFFVVLTGTITSPLEFLRTKKQSEQIKYSDAFRSIAKLVKVRGYLSLWHGWVPTTLRDVPFSAIYWTTYEQLKLLTPDPSSFKFFIFGATAGTIAAVVTLPFDVIKTHRQSELGGGKIITRTTQPRTIDLLMDLYRKGGVQSLFAGILPRILKVAPACAIMISSYELGKIYFSERRINALETDKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YF99</accession>
    <name>A0AAV4YF99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_582711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019195">
        <property type="protein sequence ID" value="GIZ05051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YF99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11831" checksum="918FCE020F4BE834" modified="2024-11-27" version="1">MDKPQLKDIVVSKQYVKNVLMDKPKLKDIVVSKQYVKNVLMDKPQLKDIVVSKQYVKNVLMDKPQLKDIVVSKQYVKNVLMDKPKLKDTVVSKQYVKNLSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBH2</accession>
    <name>A0AAV4MBH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_175791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019607">
        <property type="protein sequence ID" value="GIX69698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7869" checksum="B34771A8EA30E1E1" modified="2024-11-27" version="1">MFEPVYSWGYLTCALKPGVEPRNFWEVKPDSYAIKGVGVAARPPRPQGSGWSDPRTLQSSQDLCQRRATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBP4</accession>
    <name>A0AAV4MBP4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_313141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019584">
        <property type="protein sequence ID" value="GIX69439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9869" checksum="FB4E9793308EA7B1" modified="2024-11-27" version="1">MELSFNLNLRLCGQRFVSLDSNEHLNPETPSSEASRLCSVDYALINPDSSLRGKLFSPSICEIIYISPSELRTNYGLFSSRRVVREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MH49</accession>
    <name>A0AAV4MH49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein roadkill</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_09537</name>
        <name evidence="3" type="ORF">CEXT_464641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019771">
        <property type="protein sequence ID" value="GIX71620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MH49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="12"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="388"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX71620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="537" mass="62107" checksum="AA102609D9A693D8" modified="2024-11-27" version="1">MVAETSSYNQYQFTYVWTIYDFVLCPQLQGSAIISQTFVVYELGGTSWRLYLYPRGKTNPDYVLVYLYRESNGCWKNQVVVDLKISIENGEGVQISCKLANNVLFEENDIWKGIQFLKREKLMWFLQNSNSNTLILRCEMSVNIAIDICKWSEYTDLQALSDDLLNLHKGEVFTDTRLRKLDLPLSEIPADLYSIASRFRITDLIQKLKSYPKLCYYYTFLNVEQSCFVWRLKKRNVTEGNSTCLVRIVPTESLYVDNVNVSCTIKTNLKDNFVEDINIAFYIDDIQENIPILLSCNVFATTSSNYLIGCRQRNHVFKNDSVWRISMQCNEIPFGDYLDVTCEMSLCDGVTSSKVRECVMLPNDIPRYHDFSALSSDMFRLLASRAYSDFTIVVGDHAFAVHTAVLVARSPVFSKMLQHDMVEKETRRVVIRDVRPVIVQLMLLYMYTGTVRGLEFNEAIDLYEAADKYFVDVLKKRCAHLLLSIAKEDNLCLLFDLADKHSDVDLKNRVYEIIHSNNYKNCAQNIAEQLINVVFKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQF4</accession>
    <name>A0AAV4MQF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_617911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002477">
        <property type="protein sequence ID" value="GIX74149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13048" checksum="E1F06F848E6B5793" modified="2024-11-27" version="1">MGHVCARDSIHHRLAFPSRGSIILSEGWAVNLLGRRRSSNTIIRSTSGQNLNGRDGLKFVFDSLRFVLLEITIEIVPRSKCGIFFFMFFVSGFAFPWELLDRFDGQLRDLMLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXC2</accession>
    <name>A0AAV4MXC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_138061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020258">
        <property type="protein sequence ID" value="GIX76519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8768" checksum="0F8D015C33F547D3" modified="2024-11-27" version="1">MLKSHMENTEFIDGKVYLAKLRLPMQHESTNHSIFSSKLTNHTFSIAEKQIAGDSFGALLFLYTVSRYISFPSTPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXQ8</accession>
    <name>A0AAV4MXQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">FMRFamide-activated amiloride-sensitive sodium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FANA_0</name>
        <name evidence="14" type="ORF">CEXT_633231</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020296">
        <property type="protein sequence ID" value="GIX77048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF300">
        <property type="entry name" value="PICKPOCKET PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX77048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8312" checksum="E3A843AFC1878EE9" modified="2024-11-27" version="1">MIKLKVYYDTLEQLTYEQKPMFEDSEVLSQVGGQMGLWLGLSLAAMFECLENIVLLWHYRRQQSKETENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYE1</accession>
    <name>A0AAV4MYE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_252491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020282">
        <property type="protein sequence ID" value="GIX76728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12099" checksum="133399E1D679BF23" modified="2024-11-27" version="1">MRGCPAGSRFGGDGEETAVALPPPPLSAEEVVVVMRRAVFGERRTTAQAQPHGDQVEKKLFWRRKTRTTHARTHVCTYVPPTPLSPVGERDQDKKEKKYDGEGLDRSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MYV1</accession>
    <name>A0AAV4MYV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_806221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020257">
        <property type="protein sequence ID" value="GIX76497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MYV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10432" checksum="1B57D63912BD29D6" modified="2024-11-27" version="1">MTLELSKIHSSFISPSNPSPIVIVKEGHEEAPASHTAAATSSSRIAYCFCGKYERPRTEKKIVLQRAIGGVPISIPNTGPNHRNSASEGDSPKESADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0K6</accession>
    <name>A0AAV4N0K6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_305331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002712">
        <property type="protein sequence ID" value="GIX77052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0K6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18975" checksum="66529861566FADC8" modified="2024-11-27" version="1">MKSKPSAEATSKKTLMLSHLMQFPTEVVTEEFENTSTKPSHQKISEIADLGSVEVENGVEILNKEKLQDIKIKKKGKTKSKEKGDQRLDENSDKKDKNEPQKFTVTDAPAKKSRENSEQSVKLLLSISEKSRHRDSTHREILSGFYSGKRRFRVMPGETNKNQERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N120</accession>
    <name>A0AAV4N120_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_702411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020324">
        <property type="protein sequence ID" value="GIX77351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N120"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12099" checksum="12D36F0902944635" modified="2024-11-27" version="1">MRHYEDNYHRISASITRCKCKVNAYSNTIQKKMQPDTNPIIHTQTVFNNYPYLRRRLSLSESICEFAKTPVHLTSLYKTPDFNLWPSIIQSPNGSTPSEELIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5A2</accession>
    <name>A0AAV4N5A2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_264308_1</name>
        <name evidence="7" type="ORF">CEXT_619521</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002953">
        <property type="protein sequence ID" value="GIX79606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051483">
        <property type="entry name" value="MAP7_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008604">
        <property type="entry name" value="MAP7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073:SF1">
        <property type="entry name" value="RETICULOCYTE-BINDING PROTEIN HOMOLOG 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05672">
        <property type="entry name" value="MAP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="365"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="194"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX79606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1306" mass="145152" checksum="7FB37D3D98A357F8" modified="2024-11-27" version="1">MSKSMNASIASAPRGRRKNDLMPTVPYQRTPPARSVTSSSTRKRSVSMTRLDQLALPRKHYLEANKANSSASSGTSSVLKDSIRSPTRPLSSASEHSGGSGRVPGVVNRRVRSSPRKPRPVSIAGTLPDQKQINARPFEIKATPATHHYTPNKKPTEKVEIRKVSTPSTLKSSTPKSTEKATPRLATAQKASTHKTTTPKPTTPKLTKQLESKSPSSKSTPVVKTAKTDTSKLKEKKSQPKKKADTNVSSPTPVESKEKIDVSDKQNESISSQDNDTASENEKNNSKRVISEEEARAALAEKRRLAREQAEREAELERQRQEQLRLEEEEKLRKEEEEHRKMEEEQLRLLQEHKRVEEEKLRKAIEEQQQKEEEEKAKREEELRVKAEQERKAKEEAEKQRLELEEKLRKEEIERAERKKRLEKIMSRTRGKSSGTSPSGSVSGSEQLDSGENAQESYSSGANSLDSNEAGELPSEQASVEEHLTKAEISSVGDSIEVNPTYEIGSENESLNSNELMMPSSETASQDNSLVIIPEKSNKTDESETIIDEASSVTQVSEVESTSAIHVPAGLDTNTSSETEGKSLAFESEDIKLEVVDTVEEKMEISASVVEVESINVESQENSYSDQQVSENKALASEIMHYEQHPDILEDSSKQATELDTKSGELIMSEDLAEKSDEIVLSDDLVTKSDVIVSSEDLVTKSDVVVSSEDLVTKLDELITSEIAVGEETQAQINEFEYLESKQSTEVLTQLDEDYNEVSSKVSNKSEAFSYDNDNEFLLPEPSSIPSNISFSMDGVDGKGPELLDANRGSSISSDIKLPDPIYETSDDGSISSEKHQQFDRHEDFSYIANQDMAVAEDVFSEQVSSNIELDHQMSDTFVSEAFADNQKAFSADDSEYVTQNVVLSDSQFKNNYEEIENYNMSESMYQDKLLDALEQPREIGEENVIPSLSSTSSVIETNLHLSESEFLKQNDVFNQDSKENLTSEITAFNSTEVVNQDDMSTSAYDIYSNKENLITASETGKEFETLVREDTNFNLEPIKDNPFVGNPFSGSESNMFQSQSSDNNLDQQHSYDAAEEIDYVESQTINNSDLSTKVESVSDVTFIKSDDNGAYIGIISSIDHDHSSNDFLKSNLQDEQLKNNFEFASMTDSEENSSLDSNLSQIMTVEHSEKVTIGGLNHIENSITETNSSQQVYSNGVQHNPFETEPDNNYSTTNSFPASEISNGHRIESSNPVAELHGFGQLDGNNILSVDHSKNNIFENVDAIDYGKVSPDPFLGKGNSKQISGNPFLLQDDQKQVLMTPDFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7Z5</accession>
    <name>A0AAV4N7Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002986">
        <property type="protein sequence ID" value="GIX79925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8582" checksum="C6A789D9A0C75D20" modified="2024-11-27" version="1">MSDSGGNDIAGGFSRVDSVIFVSQEFICSVGGSVDIIAGIIDHFPPGVLKKTDGFFSSSTTPYTGEATSQIFLRLMMLDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NA04</accession>
    <name>A0AAV4NA04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_56131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003043">
        <property type="protein sequence ID" value="GIX80531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NA04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8727" checksum="CCE1F5A6D5C8116A" modified="2024-11-27" version="1">MQACIENFAHCTENGVSIESRDHQDCWILSFNHPRLDIRHLQHLRLFVSSRSGRLVQGRALVNYNQPRLKLVTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAF1</accession>
    <name>A0AAV4NAF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_427771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003150">
        <property type="protein sequence ID" value="GIX81647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9360" checksum="EB491D492E6D066C" modified="2024-11-27" version="1">MRTSPIPQGTTSKGRGPWKRTVLNICRMKGGSYTTEVGEHQKLEKDARFTSKRIAARQKFDAEEKRGRMKNTRKRYWNTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NF50</accession>
    <name>A0AAV4NF50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">X975_16893</name>
        <name evidence="8" type="ORF">CEXT_403731</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020741">
        <property type="protein sequence ID" value="GIX82049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NF50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008508">
        <property type="term" value="F:bile acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361:SF28">
        <property type="entry name" value="P3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX82049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="274" mass="30528" checksum="DF8A6EB010F7847D" modified="2024-11-27" version="1">MLYHESPDNEHLNHNHLPQVHLVRRLTNIGFPILAFIEHALLGLVPACVKSYPWPDSHGKEKKKNFNRVQKTVTMTTCSTIAALGMMPLNMWVYGQWLETGAVTIPYSKMSISLASVTAPVGAGMFVRWKYPNAAPYITKTGSYAGFAIIFICQTMELIIFPDIFDGIGWQFYVALVNIGTALTVISLSFPIEMQKKFLRSPGCILCPLITTVTVSCAFYQLYKRTCFKNSLGSCEKKLNGLGVAIPMPVVEKVVNGKPEEMQSFIPQEKLTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFH9</accession>
    <name>A0AAV4NFH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Otoferlin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Otof</name>
        <name evidence="7" type="ORF">CEXT_539341</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003347">
        <property type="protein sequence ID" value="GIX83572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04017">
        <property type="entry name" value="C2D_Ferlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037723">
        <property type="entry name" value="C2D_Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037721">
        <property type="entry name" value="Ferlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546">
        <property type="entry name" value="FER-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546:SF60">
        <property type="entry name" value="MISFIRE, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="C2" evidence="6">
        <location>
            <begin position="51"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX83572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="238" mass="26943" checksum="955E806CA104CCD9" modified="2024-11-27" version="1" fragment="single">LREERSRPWGLDHPGQAADVPLVGAHQAQEALPQGTPKGYDSSVEIRNVEKLQSAPPSFIRYSEKQVFELRCHMYQARSLIGSDSSGLSDPFARVLFSDQSQTTQVIDETLSPTWDEMLFFNDVVVYGNQEDIREDPPGDRCGDLRPGQSGQIRIHRAHHSQTSREIFGRALLQAEFPPSLEWYDIFRGSEQAGELLATFELYNYPNRTRRARYQICLSPKKMSGDPTGAPFCPFLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHK3</accession>
    <name>A0AAV4NHK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_661011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003333">
        <property type="protein sequence ID" value="GIX83436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10303" checksum="5218ABBEB2B56339" modified="2024-11-27" version="1">MFCYLNELLFSSIEWPPQSNTSPYTSLSAFLAKKNVCFYQPGSHPRGLTYKTRQKQTTEICGTNHKEVAMISDYVAFLAISLNGYPVKCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKF8</accession>
    <name>A0AAV4NKF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_164681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003492">
        <property type="protein sequence ID" value="GIX85246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10741" checksum="00BAF7DE540E5A34" modified="2024-11-27" version="1">MRVHTNLILSSHDQPFSRKLTADIKTSGGAPANSPKSLAVKPIVSHEWFSQPYWSPILPEQPRPPVQLASPFRNKSIQYLLLSHKSFCTDVHSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM97</accession>
    <name>A0AAV4NM97_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_386771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003513">
        <property type="protein sequence ID" value="GIX85425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10749" checksum="2A55AA416191676E" modified="2024-11-27" version="1">MPGSQEMRKMDSWMLHFRPLQMGPEKTSHKRNVPRLNSICQYIFTMLLCCWFLISELMDWERLRSLNATCKKRFSRVLLVGKKLIKSKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNB4</accession>
    <name>A0AAV4NNB4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FRAS1-related extracellular matrix protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Frem2</name>
        <name evidence="5" type="ORF">CEXT_698261</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003575">
        <property type="protein sequence ID" value="GIX86266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNB4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051561">
        <property type="entry name" value="FRAS1_ECM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45739:SF8">
        <property type="entry name" value="FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45739">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="28"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="152"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Calx-beta" evidence="4">
        <location>
            <begin position="274"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX86266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="464" mass="51843" checksum="2C0CA4D62CA9C0A3" modified="2024-11-27" version="1" fragment="single">MMCSRKKEIFDIELEEPVSAALEHPLLAQVAIIDKEDESTVFIPEETYEIDEDIGRLEIPIKRKGDISKEMMVICSTEPGTAQGTSPLSIVSFTDYISRPENHKSIIHFQRGEDLQFCKLIIIDDSLYEDEETFTVKLTTPLGGRLGDHNQTTVKILSDVKDVPSIYFGDMEQFVDESDGYVEVLVWRTGTDLSRPSTITVQSRPSEPITAEAGLDYIGVGRNLDFAPGVTMQTFRVTILDDLGKPLLEGPESFELLLRMPMNAVLGTPDKMVVVINDSTSDLPKFQFKDSAYIVFENDSRLNTVVTRNGDLKHSAAVRCYTRQMSAKAYDDFEERPNTDDSLIVFQPDENEKLCSVNLVDDTFFEGDEEFRLVLGSPISDSAGGAILGHRNATIVTIKDINDKSVIRLQKNRYTIKEPQNSKESSILQISVLRTGDLSKLSLVRAHTKDGSAKSGLDYVPYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NVN0</accession>
    <name>A0AAV4NVN0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_705101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003713">
        <property type="protein sequence ID" value="GIX87800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NVN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="15023" checksum="A0219DF71EB97E91" modified="2024-11-27" version="1">MCTWGKGTENRDKKMSRETGDEIKKPIKENLLSVCRIEETEWWSTLREVYCKSKCVKFESLIEEFNYLLIQSGISRQLAVPKTPEQNDVAEKMNPTLFNMARCLFLEFAFRMHYGQMWKNPYTMFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P453</accession>
    <name>A0AAV4P453_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_392131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021467">
        <property type="protein sequence ID" value="GIX89982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P453"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9760" checksum="86D949B7B1CB4730" modified="2024-11-27" version="1">MAAVYICFPLSAFGFPLCEGFPAQPMGVFFYDLLSAFLNRALRRDQTIQFTFQTQCWPLLLEENISPLLKFEYFYYPKGLNTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4U9</accession>
    <name>A0AAV4P4U9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167223_1</name>
        <name evidence="1" type="ORF">CEXT_135152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003970">
        <property type="protein sequence ID" value="GIX90776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4U9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="490" mass="56628" checksum="CF13CBB1233F07FE" modified="2024-11-27" version="1">MAKKKSPNSLYELCIEETSHYLVEKRWNGGNTNPFSQINCNIVNDLFQFLVINMNIKKPSPLELLLKSGQLQNLVIDGIDFREKQWRSVMKILLEEGDGCRNITCIILPKSFQNDEKATLEMLIEKCPLLEILEVWTFFNPLVLQNCKRLKEVRNYFTGRKEYRYFQNESVDTLANLQNLKKFAIFHSRKSSSYYKDIAKLLQNHPKLVSLGNTDSSWAAHHIYTTCKLDTVLRFGLKECFWGFNRCVKKFNPRKQIAYTQQYSEFVKSSVALFPLVEKLSIVVYHRNCLEHLKKLKHLCVLEINFTLCCGLLARTAFTSLLSEIGPQLKILSIVVQSTMPVDVVMKYCSNVVHLDLCCSAIVQGRIETDSKNFMHLKKLIVHEVDEESLKYLLRYSLNLRELLLINALCLNDTLLHKILKMKSLSKIVTLGVKECSLSRQGLKVLIQKCVNLEKVAFDTLDGDMTTVAKELKRDIRCIYLYMARSLLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDW0</accession>
    <name>A0AAV4PDW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_593191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004331">
        <property type="protein sequence ID" value="GIX94079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10143" checksum="6095E8F749DF19FC" modified="2024-11-27" version="1">MFQKLVTRMAYSQRRAVFLLTIFIAGLALELVTISNAHHHHKHNNMEELLILTGIIAKVLQRNHHHKSHPIPIPVIIPVHHHGHHHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PK42</accession>
    <name>A0AAV4PK42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_504931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004657">
        <property type="protein sequence ID" value="GIX96501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PK42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX96501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="35441" checksum="C37F5F7F9C91A784" modified="2024-11-27" version="1">MHDLDGFVRKESPQVLIDENLKIDLKNFAKSINNSRVDNPSRRKSRMKDKKIHAQERVRQDREKYISCDNGTSSDKTNNFPNNRAAEAIKNRRYHGINESNEFIRNQTPKGTEDPLKTDLKNFAKSIKSPYLGNSLKPKKGQDEQFFVKVISAHGRERLIPCDKDGSNRKSSDSFYVNGNTSSAKKNEFLHEIDEIKNIAIVQANALASYQETVISDGLASNIRNFAKSLKDPFNKHSENLSKGQGPHAHIERSKQNKKKLCHLVILPKRRIVFLMWLVLLNWTVWMLYLQKNRNQNTMKLLLKIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQF6</accession>
    <name>A0AAV4PQF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_355891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005031">
        <property type="protein sequence ID" value="GIX99339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17863" checksum="03304E31184252FA" modified="2024-11-27" version="1">MEQVEIYQDYTLGLKKIPKWEFYFQNKLNRVSDLELAFQSICPFCDLRISFPETFSCPLIPDKTRASSHSEMEDIRPVYIQKGPTEVQTTFPFLFFQNIFARRKKNSSQGLLSTNIQNFILNEEPREEKHFTPAERAKPKCIPLESEPSSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTQ5</accession>
    <name>A0AAV4PTQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_509641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005142">
        <property type="protein sequence ID" value="GIY00100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="254" mass="28794" checksum="B7FC5CBF25488863" modified="2024-11-27" version="1">MNYREHLHQNLISVSKKSLISASLRDNRPFRFCDLTLNNLRRFEKNEILRQDIDDREQLTTSREKTRAQLLNTRDTFLHKIAVIRKKYVIAETNKQPFSKLQCIEKKAEIPLHTMVPGIDQKKSDIPTAQLKFETLAMVYQRNASTCTRMVCKIGILRSWSLCLSCTSLSSCCQNGNFDGEVADVSEAGKLLLTRRGDAVILTAAAEAVTCTGLVSVFVIRQTSSSMSESNTSALVIALWSRMQWEFGLWSLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5F3</accession>
    <name>A0AAV4Q5F3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_353101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005566">
        <property type="protein sequence ID" value="GIY03341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5F3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9069" checksum="2DCD93391329FAA2" modified="2024-11-27" version="1">MTLVSQSLAQTNSAKPSSRDRIGLGKKRQEKTNYITTNSMKPWLHLAIFNRDKYATLQLASRTLCEFITIISSILQLTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9K4</accession>
    <name>A0AAV4Q9K4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_459161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005872">
        <property type="protein sequence ID" value="GIY05701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9K4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7934" checksum="D89F563410B2F580" modified="2024-11-27" version="1">MHYELRALLAVARIEAGALERDVVFVTEFDGKNVLATGVDGLGNILNPIRGELSNKILKRNKLEVVGKSCVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMN1</accession>
    <name>A0AAV4QMN1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_13374_1</name>
        <name evidence="2" type="ORF">CEXT_219741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006581">
        <property type="protein sequence ID" value="GIY10933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="37738" checksum="451ED3A3D4F8114C" modified="2024-11-27" version="1">MQILWLCFISNYKDEWAAMIVVFLQLWIYVSVYRSRTKFRLLTEELHRISNMLRVYTLKTKKMLKIYIWVYCLFVTFMTVFLEATLFNSGMISHEQHKLRSSELIPAHLKEHSVTIMYCSFTSITLVGHFFFATLPGYYCFVCCCMKQFFLHFVWKSKSLIAHQDYQSILEIYKEMNKTMIMMDNFLNLPIFISVVNILTSLFWYGYSFAFPPNADNVTGIFFAMGFLQYFVLLLITLIPAAAANQAAEMARGFVLSLPAWFPKQYSMIKVHVRRNFMHKTTLTLLEIYRIDKSLLISAIGSLISYGILVGTLGSVQNINNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNC4</accession>
    <name>A0AAV4QNC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_353461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006527">
        <property type="protein sequence ID" value="GIY10441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7771" checksum="96366255AA3319F1" modified="2024-11-27" version="1" fragment="single">WRVEAVQVLLFPISDVNFSLFLIRYLGKRKKMLFPLQELRGGIIDFGYKGVSHGLFANKFRPEWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNH6</accession>
    <name>A0AAV4QNH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_119101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006405">
        <property type="protein sequence ID" value="GIY09611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="447" mass="49530" checksum="A15B3D2399BA6B59" modified="2024-11-27" version="1">MNQERGHISFIRGSTIQQMGIGITTSTKHPGGVLHETKNHHFSGVINRKMPNHGIQGPDSTKTLAPTNPDLKSVVSEKKPHFPEFPDFNENAPEGRSSNSEPFKPDNSSPSEVKPDSFDSERGTARFNEKESSEDNEHDTESFKPDISRFNVNPDSFDSKRLSSLPNEDESSEDDKHDNEPFKPDSLDSNRESSLFNENESSEDDNESKPDTSSHSEDQPDSDAKPGFTSLFNEDTSSESDTRPSGNNPFKPNIPSFGRNPNVPANLYPKPATEQVNVNTAFQYEQTGINTFRPNIPSSHFNPNVPANLYPKPATEQINVNTAYQYEQTGINLPKQETFHESKFKSTYSSNINPALPFDSKPSSLSGNRNPSRIAFQTVHKSSTTWNKVASKDGSQFNEPLALRPLPPPAPLVPGPLPLLYNGPGPMMVLQEFPHVAEDGMLLVKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT00</accession>
    <name>A0AAV4QT00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_262691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006848">
        <property type="protein sequence ID" value="GIY12778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="228" mass="24736" checksum="E1609AC52A71CD19" modified="2024-11-27" version="1">MNITPRLTSIVSLSEEGFTQILLLDLVSGNWNSPFLFREQKMSQKDFNSICGMKPNMHKTSLQPIPNLQQLATQALEGSATQSGTHVTCHLTTTPPDSSPPLCHESSPSLFLPSIFFSLVSTCSKWNRGAGAVLSTQSSPGNVVIISGCPYLDRVTTSCCPYLNGTTTRCCHYQDEVTARCCPYLDGVTIRYCSYLDGVATTCCPPLDRVTTSCCPHLNGVKSDVVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTG6</accession>
    <name>A0AAV4QTG6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_196011</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006643">
        <property type="protein sequence ID" value="GIY11417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Lipase" evidence="5">
        <location>
            <begin position="14"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY11417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11370" checksum="6364845D95873E71" modified="2024-11-27" version="1">MSLLISQRSGDKADYSRYLSCNHNAAPQFFLRSINKAQCLFRSVQCPNYDDFLDGQCPPDSSITDLMGLPAQKIPGLAPKSKFYLRTMTDSPFCLQDGDEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QY24</accession>
    <name>A0AAV4QY24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_732751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007051">
        <property type="protein sequence ID" value="GIY14164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QY24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9858" checksum="DCC8048DB355FB2E" modified="2024-11-27" version="1">MKEKLFLSTGSDLFSRPMPIQSKSKKHSRHVQAGTLFNIINSTAEDYLSIARDGSVATIFAPLTETGRPGENVSLKLITPRKQTPKERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R265</accession>
    <name>A0AAV4R265_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pol_1361</name>
        <name evidence="3" type="ORF">CEXT_200261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007137">
        <property type="protein sequence ID" value="GIY14724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R265"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF4">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043596020" evidence="1">
        <location>
            <begin position="20"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="104"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY14724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="34830" checksum="D893B2E9527CCA10" modified="2024-11-27" version="1">MLHCAPIVTASILLPTGVAQTSPSSIKLKQNLPLLQLATPFNLNTPIQILSFANAVSTSSNTQNINTNTNSTLNSLQELAQDNELILILQTLHKIAPQIKQATSMQQKMLIVLTAFNIFNNYFLGGDLNSHHRKWNCSRANSFGINLYKFTNDNRLHIAAPPTPTRYGTNTPSTIDIALFKNLNYRYTCESVSALTSDHNPVIYHFDLTIPNIDSQNYNIPNWSKFTQHLSTAIYTPHDLNTISGIEDSIKLLTDIVYTCHDSTSKHISSNTKFPTLPMILKLKSKKEIDSGKSGKPLDTHRINKIIMILTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDU8</accession>
    <name>A0AAV4RDU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynactin subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dctn2</name>
        <name evidence="7" type="ORF">CEXT_363821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007726">
        <property type="protein sequence ID" value="GIY19199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028133">
        <property type="entry name" value="Dynamitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15346">
        <property type="entry name" value="DYNACTIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04912">
        <property type="entry name" value="Dynamitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0243">Dynein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY19199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="267" mass="30069" checksum="E4ECB43A4188C7E1" modified="2024-11-27" version="1">MANPKYADLPGIAHDQPDVYETSDLPESEQGNLSISDVIVDQCDSVETLKVSPNEAFNKFKGKSLDGRNVDFTDGIGHGRKIGYDIRSGDWEMIGDHTKEKENPLQAYNRIQYEVKQLFEQVNEMKESSSKDSESSQVPPVVLVQQIEQLQKELQDLHMEKILGSEALEEMSDPLGALHKKLLTQLETFKNVPATDKKTKTATSSVTSAEETVKYELYVRPDQAKLEQASKVASLEQRLRNLENIIGQDKKKIGLFYDILSFSSFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4REX4</accession>
    <name>A0AAV4REX4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Diphosphoinositol polyphosphate phosphohydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_176881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007670">
        <property type="protein sequence ID" value="GIY18755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4REX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="37" mass="4355" checksum="CF77F350C184E7C1" modified="2024-11-27" version="1" fragment="single">GRKRKWFTVEEALSLLSIHKPVQCSYLKLLTRNDKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMM2</accession>
    <name>A0AAV4RMM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_96671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008027">
        <property type="protein sequence ID" value="GIY21530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18152" checksum="D79E3A6BCF0AD714" modified="2024-11-27" version="1">MELDEPSILKHIHNSLSKRKQPLQHPIITSRWVACNAPHTKKEKSQSRSGKRAPISQSKTTCNEAGDYRFFAAARITGVAWVWGGRPCESCHSISEGQVLLETLTSHAPRSDICATHSLGLRISFACCRGRERFYSYSSARMMPRGRQRVCLVADVALVIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUS7</accession>
    <name>A0AAV4RUS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_782881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008460">
        <property type="protein sequence ID" value="GIY24884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14781" checksum="5542CD8AA97CCD73" modified="2024-11-27" version="1">MAPFRESIRFTAHCNFVQTEDGPMPVEIAFGYSLGTVDNDEADPNKNRRCIGRSMQPLPFGYPGKYTYKKAIAQVWERYTEKDKGLGWWVAVIGDTQQNFSSIVVYLSWTLICFGTVPSTKSYPLQIGHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBP4</accession>
    <name>A0AAV4SBP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_443611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009172">
        <property type="protein sequence ID" value="GIY30086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12181" checksum="6688C7EABFC493DB" modified="2024-11-27" version="1">MGGRQFHYRGFSYRAFAKTLTSRLSQRADEHAEIVANTTDGTFRSGQGSESLFQVEADNSIAVDPLTAYLQNTDKPSFTQKKTDTQRRLLAIPRTARFTVDNEGFSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SCU9</accession>
    <name>A0AAV4SCU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_599261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009114">
        <property type="protein sequence ID" value="GIY29703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SCU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14725" checksum="89F6B036F8784094" modified="2024-11-27" version="1">MYCNCFAKLSSSISFFQTQPVTKKKRRETTCSPPTVTVHSPAGWTGQPATKRQATIPANDHQSWGLLEACQEGQLVKRCARFPSSSHGGSGRLTNGCWRISLLFRCGFMVLFRGRDVQARIVSFFVGFSLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SP84</accession>
    <name>A0AAV4SP84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_609331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009857">
        <property type="protein sequence ID" value="GIY35099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SP84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14373" checksum="A9700EF48FF88F7D" modified="2024-11-27" version="1">MFLWKQTWTTANRTENAVPDNFRLPTHFAEKQPTCFPIIEKNPPFSLDATAVKTDFHSGGNVGARFKGNIYSGRCDSQTDRMVKQSSSSASFLIEKAPIPDIRVPYFYFPGILSRVNLITNRMLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWR2</accession>
    <name>A0AAV4SWR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_363421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010172">
        <property type="protein sequence ID" value="GIY37421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10212" checksum="A45DCE16912881C0" modified="2024-11-27" version="1">MQQSSLNGAFYQQGHLTFDNFSTGDTLIKSYAQMPLRFVQHIEDQQIRLQSGSVSNQKNLLIIASKLDSRCQHVRCIKLIITEGNTSIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY66</accession>
    <name>A0AAV4SY66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_548911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010459">
        <property type="protein sequence ID" value="GIY39398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13937" checksum="200A5664C9AA5F1E" modified="2024-11-27" version="1">MVAVPQSERHFLTNYSESDARLISTTNNKSIDIIPKSDNAITSLSNSQPNKINHMESTRDEMNQHHLPLTEVRDPRKQNKFLQSFKIFLDPMFILISISRSVTLFFFFFIPTVIVDFCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZ83</accession>
    <name>A0AAV4SZ83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Repulsive guidance molecule A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Rgma</name>
        <name evidence="3" type="ORF">CEXT_528361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010403">
        <property type="protein sequence ID" value="GIY39100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZ83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015026">
        <property type="term" value="F:coreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030509">
        <property type="term" value="P:BMP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040287">
        <property type="entry name" value="RGM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009496">
        <property type="entry name" value="RGM_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31428:SF6">
        <property type="entry name" value="REPULSIVE GUIDANCE MOLECULE B HOMOLOG DRAG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31428">
        <property type="entry name" value="RGM DOMAIN FAMILY MEMBER DRAG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06534">
        <property type="entry name" value="RGM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Repulsive guidance molecule C-terminal" evidence="2">
        <location>
            <begin position="58"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY39100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="264" mass="29599" checksum="07B5A3F610A964EF" modified="2024-11-27" version="1">MHFIQSNFIKKERPLQDKLGEIHGSDSVTIRFVSDSFSYINGTCTSIQSNFIKKGRPFAKVTVIIRQHVPCAIEKTYEAQADFLPGVFADGSRWSGPGVRIHEEVPGKHIELNFRYINTRIIIRQSGSYLTFAARMPSAIAVQGAQENTLELCVRGCPRRERIDFERVLETSTGPKNEAIAACRALNITDFYFDACVFDYLTTGDDSFSVAARDAMMDIGPQSVVNGSLPVMPRSVESGQKSTMHPFPMLFVVLGLMWFFLVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1R8</accession>
    <name>A0AAV4T1R8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_163331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010222">
        <property type="protein sequence ID" value="GIY37833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9728" checksum="73469FCD6B5BF2E3" modified="2024-11-27" version="1">MKVKVLYLSLFLLYRDTKYCIQNILYRDTKTWTYCGTIKRGVAQEENKTKLSFFGTFPIVNCATHIRNTKPNENDSKPLNGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2J8</accession>
    <name>A0AAV4T2J8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_361351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010402">
        <property type="protein sequence ID" value="GIY39092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2J8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12045" checksum="7D1DDBC3ADC4841D" modified="2024-11-27" version="1">MPGEVPIKGVLVDTMDAITPSYLLTAVYRANFFGQFLLASFLAKTLSGEVGSLTDRNGRFNSLISINSRLPSQILGPIFCGIIPRQDPVWEVGSIILLSMPPSGEESVTDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T6C8</accession>
    <name>A0AAV4T6C8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_533451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010684">
        <property type="protein sequence ID" value="GIY40987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T6C8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="333" mass="37159" checksum="DABDB1929A6B33DF" modified="2024-11-27" version="1">MTVRKKKADADEREREQMSNQPFDKLVVEPEGVAENAAPEPENAAPEPENAAVAAFGINLINDPVEMDVENLEHDALDEKPLDAELVEEAVLAALDPIAEAALNHGAHSVNAPALDPIAEAALAHGAHSVNAPGLDLAAEDDLELAPELKAYTEYYPDKKYAVDENGDEIYARTSEGDEVYLKIDNQYVFAKKTIKYSDKEPAKEVYYAALDRNGLVKYPTDLETGRPIFPKGPMGGEIYVFHPKTNERIYPTAYGRMIYAIYPNGDEFLLKKSAGFMYARNNQHGELYPKRANGDEYYFNNGSKEVAARDEHGNYYYAKTSKNCEVYPKEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T722</accession>
    <name>A0AAV4T722_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major heat shock 70 kDa protein Ab</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Hsp70Ab</name>
        <name evidence="7" type="ORF">CEXT_460061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010845">
        <property type="protein sequence ID" value="GIY42388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T722"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000024">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY42388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14745" checksum="4C5200747D938CEA" modified="2024-11-27" version="1">MTKGRLSKEEIERMLNEAKQYEKEDAEQREKVATRNNLESYVYSVKQATDSVSDDKLSPADKTKVKEVCDNVISWLDNNTLAEKEEIEHKLKEVQSELSPITTKMHQAGGKFNPGQQSSRTSGPTIEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFW5</accession>
    <name>A0AAV4TFW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IRF tryptophan pentad repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_228489_1</name>
        <name evidence="3" type="ORF">CEXT_76691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011223">
        <property type="protein sequence ID" value="GIY45025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001346">
        <property type="entry name" value="Interferon_reg_fact_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00605">
        <property type="entry name" value="IRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51507">
        <property type="entry name" value="IRF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IRF tryptophan pentad repeat" evidence="2">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY45025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="229" mass="26794" checksum="9C75D82CECD55840" modified="2024-11-27" version="1">MRPTIKLIPDFILPHLERQTYGRHLIWEDEKEGSFKISRIHQSSELWSDDCIGVYKAWSLEKKLWKSDDDKRITKAKHRLITALRRSPVIEVMKKESAYYRFRFIHSKKSANERKRALLELKSNTDFNMDSIQIATTNDDKPPKVKELYITVIDKTENNESVSNVPSHELQNESKDEELSTPSDLSDEIIPTVNNSEDNFWYTSKCCCDILLDSTLLPNENCIWHGIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJ22</accession>
    <name>A0AAV4TJ22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_433741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011447">
        <property type="protein sequence ID" value="GIY46618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJ22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8860" checksum="82001BA5C65AD8C9" modified="2024-11-27" version="1">MCVRNVPSGGSISPLLVLIMNRLVRFSFFSLLLVGIPKELLFKGPKVSGGNPQLVTHDKAYQKYRRASCGTHSFNPTANIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJ85</accession>
    <name>A0AAV4TJ85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MAM and LDL-receptor class A domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_341081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011255">
        <property type="protein sequence ID" value="GIY45279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJ85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06263">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051560">
        <property type="entry name" value="MAM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282">
        <property type="entry name" value="APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282:SF151">
        <property type="entry name" value="MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00137">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAM" evidence="1">
        <location>
            <begin position="4"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="1">
        <location>
            <begin position="172"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="1">
        <location>
            <begin position="305"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="462" mass="51571" checksum="F0FD28A119A67551" modified="2024-11-27" version="1">MSRLACTFDDLNLCLWTQDTATLTWKFGNVTLTESTGPKEPVNGKGHYIYVSSYDEGGSNNEKIAKIQSAVVSSFYPESACFSFYYHMFGAHVGELRVYLVPMQDEETPLGKVVIWRRRGTQPDKWLQFKDSLNVTEGDYRLEIEAEGGNGFAGDIAIDEIAMTFGACPGVDLCDFESSLCGWKIEGSSRGKFTWTRGIALPKGPAQDHTTQTNIGYYLQAVSNGADVEENQPRKISVLTRQGNKENLKWSATKDVGKFWHYGQITISEWRTMQILLQAEKGSNNDYEMALDDILIKNSRCGTTAECNFNNGYCSYFLNETSDFAWLLGTGRVVNTQLVDPPPVDNSVENGMYIYADMTSPNLKENTEAVLMSEILEVPTKSVSCLTFYYHKNGADTSTLSVGKATLDNTNKDMQYVLKEIFSTTDNTGKGWTKKTLDVDGNQELPISYISRQKEETALVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TLI1</accession>
    <name>A0AAV4TLI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_765511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011320">
        <property type="protein sequence ID" value="GIY45797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TLI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13870" checksum="DBDFF136372F343F" modified="2024-11-27" version="1">MNTLKYTRLREGGSLNERTFKRAIVKNCNWAYEDFQTAEMVPDSTMCTLQGRFHKEDDENTCLQKSVDTLVTVGRIVRRTLEMQNRYNAKVCEESEETSRSETAKMVKKVVEKICHLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZA1</accession>
    <name>A0AAV4TZA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_330151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012029">
        <property type="protein sequence ID" value="GIY50814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14029" checksum="5F68F48AA98A5B05" modified="2024-11-27" version="1">MAACHAKPRSPEITQGSRERRPADKKREIPRQFPLNSIRRSEVKPSHKSWLAASGALLSNLVLSEINSHANITGSKRFFVVELTFSDIFQWLQHSWKTDFASTISISVSESHRKLAHLHNRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5U4</accession>
    <name>A0AAV4U5U4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_811621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012322">
        <property type="protein sequence ID" value="GIY53098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="382" mass="33823" checksum="706F460DFCC2E71D" modified="2024-11-27" version="1" fragment="single">AANQGLNEGSYYGSGPYGTGHYVVSKTIPNNYENAGAAGEGNGTLKKEYDYSSGTGSEANYHVYFSPHVSQNGQGELYYNYNSNGGGGGAAGGAGGAGGAGGAGGAGGAGGAVDYEGAGSAADYGAAGGSGGNGETLNFNSGTMTFYPASGGGSYQYEYNGGSGGGAGNAGAAGNAGAAGNAGAAGNGGTYQYNYNSGPLTFYPSGGGSANYQYEGTGDASGGGGAAGGAGGAGGAGDTSYQFTYNSGVGYGGGGYNGYYNGAGNCVCSGYGGDGSGGGRSGSGGGGSGSGGGSGGGGSGSGGGGSADDSGDGGDGGDGSGSGGAGGGGGPGGAGGPGGPGGPGGGDGGPGAGDGEPGPGGGAGGGGAWWSWGTGGAGGQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCK6</accession>
    <name>A0AAV4UCK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_806561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012642">
        <property type="protein sequence ID" value="GIY55456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7509" checksum="C8C5C44BD912D545" modified="2024-11-27" version="1">MWEGKTITMLLAKDSQKMSSSTPSNDVSSAKNFEDSPPSIHPACTVPWNIKNYVVCEGTIARGMSVGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFI3</accession>
    <name>A0AAV4UFI3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_178471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012779">
        <property type="protein sequence ID" value="GIY56568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13385" checksum="E2C70B25753E149F" modified="2024-11-27" version="1">MTNYLPLSRDNLFGAIPPPPPCSHGSPRRLLPNGFFFHILPVHSSSFPAEISPHLGSRPRLRKELGGGPCLTSVPRELRPCTISISEECVRWSAGLLISLPTSSPSTPGPAYQQAPRTSCRMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UGC6</accession>
    <name>A0AAV4UGC6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Stk32a</name>
        <name evidence="8" type="ORF">CEXT_491191</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012811">
        <property type="protein sequence ID" value="GIY56796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UGC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004703">
        <property type="term" value="F:G protein-coupled receptor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY56796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20196" checksum="EB7CB4EB0EC8BBDF" modified="2024-11-27" version="1">MNNYRKCTTPEVLHCALEPANDEGYSFAADWWSLGVTAYEMMCSMRPYHVQSSTSVEETFALINNSCLRFPKKLDEGLVSLVQHLLKIDPTERIASIQQLQKHNYMATIDLTAVYNKQYTPSFVPSKKQLNCDPTFELEEMIIEAKPLHKKKKRLSKRNKARAAAPTPQLSQDDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHF5</accession>
    <name>A0AAV4UHF5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_35391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012869">
        <property type="protein sequence ID" value="GIY57193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHF5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11244" checksum="DE0677488AB266CC" modified="2024-11-27" version="1">MAVYMLIKSVKSSFVYVLFCVFPFLFSFFLPCTGLEDFRGPVLQECVPLQALLWPRKANPVHAHCHSHTMPREATSKVSSCSLPWPTKLKESVMTPLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHU4</accession>
    <name>A0AAV4UHU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_412011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012911">
        <property type="protein sequence ID" value="GIY57487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20685" checksum="AEE9148D3AE3435A" modified="2024-11-27" version="1">MNGFSGKKDCRNISKYLYLQRRNFFLEYSVYFYPDPNLRAHRFSLPFFVMRIFFFRMSKDGPWFEQFGRKAISGLTFALVIDTETILSPSKEKVSGFWRAKNYLIPDRHPIGSSNLSPESFPNHHLAIHGDTYPENTLSNTTLQTPSPERNLAISRARINTNLCSITSREPSYVSDVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UIE0</accession>
    <name>A0AAV4UIE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_39021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012920">
        <property type="protein sequence ID" value="GIY57523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UIE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12685" checksum="D38F15054B3F0D24" modified="2024-11-27" version="1">MQRTHLVTKTGRWSLGLGIRSESVVCYGTETSCLVEKKRKQKHSLWEVVLRCEERAILAPAPPPLPHLPHLDPRKCLDRPPREESLSSRKVSCWLLSDSNAKWNERASESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPR0</accession>
    <name>A0AAV4UPR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_628081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013251">
        <property type="protein sequence ID" value="GIY59876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16750" checksum="334B4A1B16A38F5A" modified="2024-11-27" version="1">MSCSGAKVLMVNSKALGRSRFRRGSLSIWGGGTGRGNIDQALLSLHHYPKPRPARKKGGRGIPTHENFLPSIWTPERPVCDGEPEGGWSVATHARSTWEKRDIKAIRCVKEKKRLYIRTLGMSYQNPFSIRIKIRSGHLSKYYIVLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UR00</accession>
    <name>A0AAV4UR00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013328">
        <property type="protein sequence ID" value="GIY60427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UR00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11207" checksum="D51AA1298EE2695D" modified="2024-11-27" version="1">MVDGYISTISFYKIHLDDGILFSGSSIERKEKNKVITDKEHRYRNFRIDPSIDKEAYDYIVDDEDRMGNVWENCSKTAAVEIFRLKILISQSPLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8E9</accession>
    <name>A0AAV4V8E9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_83640_1</name>
        <name evidence="2" type="ORF">CEXT_745401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014089">
        <property type="protein sequence ID" value="GIY66179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8E9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="405" mass="45706" checksum="C46450B94FA95584" modified="2024-11-27" version="1">MDVEIIESKRSEVTPEHAVLIPILPNVKSPMPYVEAVAIVIGSMHIHSVLESGDFMKVYLTDTRYVDILVNQGISILGTQINVDYAVPRADKVILSNVDPIIPDETLLKVLGYYGTLETGIIHEKIALSSEYSHIECGRRRLYLTVFPNKKLPTNITISYHNMHFRIDVLVEPLSEINDECESIIPSGEERSETSAVESFEIESVVNIKPNIEELPPLQVQPTSKKIAYRNKDPNKVYSNNIAHRLKRQARKAWYGSRPLTRTQHSEMKNVMKRTAIKHLEGARGKKRGPKVLRKLSKLESRKSLTSAGNSSSLDLESKDTSIPSAATSNITQYPLKPKKLKEFLVKAKFHRFPMRVAWEFLGNKTPEALEGLKAQLLEYSNAMKNLALEGRIKRLIALLSTTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9F3</accession>
    <name>A0AAV4V9F3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_126891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014162">
        <property type="protein sequence ID" value="GIY66872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9F3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="13042" checksum="9DD0336E15C49941" modified="2024-11-27" version="1">MTIKEKCWATKFDRANFCVMIFVLMSNRVQLKLESLNFRSIFTLDCPRELRRRDGVGCSHSPSAIAFGHKSPRESQDERHRQILNGIFEWLEIMDEWTLEEKKEEESGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHG9</accession>
    <name>A0AAV4VHG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_333091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014530">
        <property type="protein sequence ID" value="GIY69429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10285" checksum="E0C3B87EB86C830F" modified="2024-11-27" version="1">MTQGPHARIGSAEESAVVSDAIRKSPGRDDLGFRCLTRWGGKMLQFPRYGAILKAMSHAQFGEAAAKYKAPSTSYDGFKASVVTANKIIDAPVKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLF5</accession>
    <name>A0AAV4VLF5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_753811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014655">
        <property type="protein sequence ID" value="GIY70353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLF5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9137" checksum="77DFAD0A7401CB29" modified="2024-11-27" version="1">MPTIRSTDENETPDVVFLYEPKKLKSKESNKDNNFSGQKRVRVPRDDQNFDLPECGSKDCDFQILQCLIDHRSTSEACK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPL2</accession>
    <name>A0AAV4VPL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_94931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014893">
        <property type="protein sequence ID" value="GIY72053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY72053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9763" checksum="386F3938959DFFCF" modified="2024-11-27" version="1">MRSTEVRVSPGINENLSLSNTTRASGKFETAPKLGSSPKTATGNHISNLIRDRITNSSIDYVPACSAFTSSFLQFSMKNVPNELITENGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPU9</accession>
    <name>A0AAV4VPU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_477111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014874">
        <property type="protein sequence ID" value="GIY71945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12351" checksum="CD2A78F15C7B2723" modified="2024-11-27" version="1">MGFKVVSRFTYLEMRIMRIRIQRSLRVFLISSSADELSIPFAGSAPIVPVCILCQVTVSTCQVKLCMPSMQNMNRRVQSPPFLDYGCCYLIRNSLFAVTENRSIYTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRK4</accession>
    <name>A0AAV4VRK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_687451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015022">
        <property type="protein sequence ID" value="GIY73015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="19147" checksum="A71C3FAA5B9DEC15" modified="2024-11-27" version="1">MSLAISIRKRATARSSFTRTANVLKEELNEVEPDKSVLDDKFIKLQTVNTELKTYDSVILDLMIAAEVPDDDLNNEVISCEEYLDEFISLSRRIKEKTDNSDLNISIRSKTDSSISACNDKRYKLPKIQIKKFDGHLLSYLSFWGQLKRFTRTRIWMMWINFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VT52</accession>
    <name>A0AAV4VT52_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SLC9A2</name>
        <name evidence="11" type="ORF">CEXT_62601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015102">
        <property type="protein sequence ID" value="GIY73567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VT52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF98">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="10">
        <location>
            <begin position="10"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY73567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21020" checksum="8C288095B28E077C" modified="2024-11-27" version="1">MFEGYAEMGPKNIITVDYMAGVASFFVVALGGTLVGIIWGILAAFVSRFTHHVRVIEPLFVFVMAYLSYVSAELFHFSGILALTFCGITMKNYVEENISYKSHVTVKYAMKMLASSSETIIFLFLGVSTVNDNHEWNTWFVVMTIFFCTVYRTIGPRFCRIKGPILISQLLFDCRSHEPLSIHQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VT72</accession>
    <name>A0AAV4VT72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_187311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015038">
        <property type="protein sequence ID" value="GIY73149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VT72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10870" checksum="2B12CDA2840A7BCE" modified="2024-11-27" version="1">MAFGQQQWRSNNNNSIRTTITMAYEQKQSQHSNNNNNGARIITTVFEQQQQWRTNSNNNGVRTATTMAYEQQQQQHSNSNNNSVRTTAIMAFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUS0</accession>
    <name>A0AAV4VUS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_710071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015117">
        <property type="protein sequence ID" value="GIY73738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15183" checksum="10A4A492954B4448" modified="2024-11-27" version="1">MWCVVFHFLRPKTFLENSNYNYNRICGLRVTTSLTSKTFVEGPDRRNSINPASLNCCRKLFLKDGISVLRCQKFLLTVVIYLKSSIAFLETMPRDVPSITNLRSLLGRCYKTLPLRRHYKPLLSLACLHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVI7</accession>
    <name>A0AAV4VVI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_131861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015196">
        <property type="protein sequence ID" value="GIY74292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12564" checksum="816B8B3F5C617D08" modified="2024-11-27" version="1">MAVLRTADPPEDDNPRLECGPEPWNFATQLDWGGAAGALGMIFRRELRVSSPIGRRDYPINWILSLESDDCRLGEDSCSDVKTSCQSLTGLVKTGRILGFEEAESGSVASVVSFGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVT4</accession>
    <name>A0AAV4VVT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_438271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015079">
        <property type="protein sequence ID" value="GIY73410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15935" checksum="8FB5CA7B9A9413F7" modified="2024-11-27" version="1" fragment="single">MLDARKNGRSSYPFDVSKDPVRCFQTFHKKEEPFFFFYRYSSHVRFLDATSCVSFQKRKKVVQTVFPFLFATQILSVRSEGGQDIAWIPSRDRVATSFVPPPNSDFVMAEHYCQSWVGHRDHKKWRSLCVRTEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDP1</accession>
    <name>A0AAV4WDP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_460231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016050">
        <property type="protein sequence ID" value="GIY80762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11491" checksum="B0CB5C7CFF1FD190" modified="2024-11-27" version="1">MADFMHTVSLLPSTTKAIFLREISCFDSNLVPLLSNSSLQVLTANFYGCDIAHSRGGFLRQRLIPPWDAVCPEGPLISGFFCALIEARVRYEILLTVLVAFGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDR7</accession>
    <name>A0AAV4WDR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_784871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016004">
        <property type="protein sequence ID" value="GIY80364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8476" checksum="A098AEF89BB15996" modified="2024-11-27" version="1">MIELNGHKSTAYLDRLIYSHTIVHLDQKHKMLLDGIDTQDDKHTKRPSSSRPPRLLEKCIISWQTIPVRNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFU1</accession>
    <name>A0AAV4WFU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lethal(3)malignant brain tumor-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">L3mbtl3</name>
        <name evidence="4" type="ORF">CEXT_453441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016062">
        <property type="protein sequence ID" value="GIY80930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004092">
        <property type="entry name" value="Mbt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050548">
        <property type="entry name" value="PcG_chromatin_remod_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247:SF131">
        <property type="entry name" value="LD05287P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02820">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00561">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51079">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="MBT" evidence="2">
        <location>
            <begin position="354"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY80930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="444" mass="48612" checksum="64D90BCFF448BA4D" modified="2024-11-27" version="1">MTRVSTNISSINPVLSAKPRQAPHITPLLPGSILASKGQLVIASANSPMIGSSASVITTMSSISLSSSIVTVTPVIMTSTAPLVTLSGNPAVALNPVSQGQVLSSIIQSNVKPCLSANNKTMLSTTYLKPVNIAAGPASFPVAVQPAAIAPAAITLSTAPLPSQQQSQPAIPQQMSTTIPLQPAKEFRLNEFATLELISDDVPDAHNKDKKTVRDENTITSESNSVESRQKPIKSREMYQDENNTEKTSQNNAEEGSESRKDHLYVCGTCGCFGLKTEYICDGRFCSPRCQTSFNEKKNAMLRRGAAKDKTKRKKQKIESVEENGIKNDAKNCEMDCDDLIIDLKEPGEAKKNFCWEEYLKKEGAIAAPTKLFKDFQTYPSNGNGFVKDMKLEGIDPKHPSLFLCFEYIFPVGWCERTNHQLQPPKGFTVQEFDWNDYLKKIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WY61</accession>
    <name>A0AAV4WY61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-type lectin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_40467_1</name>
        <name evidence="3" type="ORF">CEXT_564451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016845">
        <property type="protein sequence ID" value="GIY86806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WY61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="93"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY86806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="238" mass="27687" checksum="1D72A79AA2E338CB" modified="2024-11-27" version="1" fragment="single">NAKRKEQHESGYRKLHIHERPRNFVHQDKYPLWASDPSYSDCGVVSYRKEFRVKPFSCSNSAVILCEKELPCKYNNLPFVEYHQKCLSIFPRKDNYMTANNICNNFGAHIFPYNSYDDSDSVGAAIYSSMTFDGGIYAGLRKTELGEWKYDSGEKETARWDPEDELHQDCGVYGFLKNLSIGLFTMSCDDKLRLLCESGKIYFRTSHNNAHCFLLLLFLRVNALRIFWCAYLPVDFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYL9</accession>
    <name>A0AAV4WYL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_50331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016836">
        <property type="protein sequence ID" value="GIY86719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13405" checksum="4FDF027AF288F583" modified="2024-11-27" version="1">MSGVPPTAWRIMISSPQVLPVSSWTCPSQRSAPCMVHPSVFLNRCPLLTTRGRPTRVFFPAFICIELNRDRPAENELRPSFIRVRLIKTFEVFSKPFPVTAPYGDQRQNELEIQNCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAF2</accession>
    <name>A0AAV4XAF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_218721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000036">
        <property type="protein sequence ID" value="GIY91648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043383094" evidence="1">
        <location>
            <begin position="20"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8358" checksum="2B6F1F667DD6D8E7" modified="2024-11-27" version="1">MCVSHLHLATLLCYQTILSIYSGRISLDMEVEIFSKINKSHCFQKQGDFKESFINKRFWSYEISHTFAECC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG47</accession>
    <name>A0AAV4XG47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_330331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000282">
        <property type="protein sequence ID" value="GIY93594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10131" checksum="2DD08BD646A61A81" modified="2024-11-27" version="1">MYCSEPGLICPQLPCICSTSHQSCIAPTAVVRDVRVLQPMFIQQDLATTTDTIPMTTDSTIMLLVTEAFWDTMDFMMVMATEEPWDTTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGA1</accession>
    <name>A0AAV4XGA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_706071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000200">
        <property type="protein sequence ID" value="GIY92808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14570" checksum="860F02BB698505DE" modified="2024-11-27" version="1">MHMYTEHPPSQSLFFPSTLQLTQLNALQLIRQQLIWGLRNNELHPIRVDKIAPLCQPETGAREDETMDEAVIMEQKALICSCCSLSWTDVGKRQMVRALHWTVLRDFGGEVGWSAYGGSSCFLGASFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHC9</accession>
    <name>A0AAV4XHC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2_101</name>
        <name evidence="2" type="ORF">CEXT_722511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000343">
        <property type="protein sequence ID" value="GIY94052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Immunoglobulin I-set" evidence="1">
        <location>
            <begin position="7"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="53" mass="5787" checksum="186336B189A473A6" modified="2024-11-27" version="1" fragment="single">MEEELDATVMYAQEGRVSTLTIKELAYKHNGNYTCATTNDVATGSFSAILTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJI9</accession>
    <name>A0AAV4XJI9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_569931</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000509">
        <property type="protein sequence ID" value="GIY95361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY95361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="350" mass="38526" checksum="5B8DB8EBD2AF99E1" modified="2024-11-27" version="1">MGHIRGLPTGGPGLTSLNSSYSPICHRTRHQTKVKIGTISNDGADSEVAETLFDINIVSCASPKGKVPCTPTCVPHINELSVVHSPSTVIQIEECDNVVPQPAMTCDLSPIHPVGNVEMVLFPSDVEVRELFPESVRFDFLQLCCNQCRRHFSSVSGLELHMKDQHGIDIHDTEELVESAPSPSKVHSSPPSELTQLGPCSGPPKRAPFGSIRPAKSLGFHHCKTSQLLHAPLDPPTPEKTSTQPKTIVNRASLVATTEQKITVKPCDEDLYEVSHVILLPTKPLKKKQFKCSHCDFSFRTRRSRDEHHVLHELENEFNALHGLVGNISLSDFDDFQLPKSPCVNLKLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKT8</accession>
    <name>A0AAV4XKT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000388">
        <property type="protein sequence ID" value="GIY94429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9305" checksum="79FEBD7491DB105B" modified="2024-11-27" version="1">MKPDWPRRGVGQVCVVVHCCHGNIEKAFLTDSVVEKNIHADSPNKSALHFEYGMIPAVIPQAVKKTFITHYPLKKGQHVSGAIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPS4</accession>
    <name>A0AAV4XPS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_351521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000694">
        <property type="protein sequence ID" value="GIY96714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13508" checksum="494667F30020D3CB" modified="2024-11-27" version="1">MDKYLKRNKNSALPLYLSSPFLQRYSTGIDFLISPDSPLMTAPAEKLPSHHLLTIPNAHSMPFPNKGHHCKATRAVASLHHREHLDIGGGRHSDCQWARNPRRTMGAPHHHHNRCQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQW4</accession>
    <name>A0AAV4XQW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_242571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000798">
        <property type="protein sequence ID" value="GIY97567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11874" checksum="3F27C0B0E9F39BE3" modified="2024-11-27" version="1">MTPRLLTNTESLCRLRRSLSGLWASLVCYSISSERDLLTLLIDVDILWLFLICPAPPCLTDHKPWIGGEELFSGVPRLKDFRRFTTCIAGCDVLDSIKKAMLRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR66</accession>
    <name>A0AAV4XR66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Metalloendopeptidase OMA1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Oma1</name>
        <name evidence="1" type="ORF">CEXT_355391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000657">
        <property type="protein sequence ID" value="GIY96420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="17036" checksum="88014D44FEBC472D" modified="2024-11-27" version="1">MIVMNCKHFFIPRNYLHFYNHNKSLLFRKSNIHTFQYTSKPSSYLYHTQRKFSKFSSVIYASRINFKALNSQLQVVCLFRTSAPRNIPAAVWLVLRPILKIAAVVTGRGIRKWWRNLPKDKKQYFINEIKANRRKKLESLYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRH5</accession>
    <name>A0AAV4XRH5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_527771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018197">
        <property type="protein sequence ID" value="GIY97661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8626" checksum="CAC81F32F4F6986C" modified="2024-11-27" version="1">MTADENGFHFAVSSMNGIWGKNSVACVSMTTIIYRSQQNIEAQIVNHITQFTLSKMSTFKEKTLVQLDTIPVRFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU30</accession>
    <name>A0AAV4XU30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">26S proteasome non-ATPase regulatory subunit 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">psmd11</name>
        <name evidence="2" type="ORF">CEXT_762431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000777">
        <property type="protein sequence ID" value="GIY97410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="26S proteasome regulatory subunit Rpn6 N-terminal" evidence="1">
        <location>
            <begin position="33"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="257" mass="28777" checksum="3B18D4AC511459F7" modified="2024-11-27" version="1" fragment="single">MYFDLCNIALDAISQDSVQSDVPPEEAHVEILDEEGLRLKEISILEQGQLLSRTGKAVELGNLIKSTRPFLNQISKAKASKLVRALVDLFLDMEACTGMEVDLCTECIEWAKQEKRTFLRQSLEARLIALYYDTNKYSDALQLGGALLKELKKMDDKNLLVEVQLLESKVYHALSNLPKARAALTSARTTANAIYCPPKLQAALDLQSGILHAADEKDFKTAFSYFYEAFEGYDSVDSPKALQSLKYMLLSKVMLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVW5</accession>
    <name>A0AAV4XVW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_320261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018249">
        <property type="protein sequence ID" value="GIY98040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9121" checksum="4776CC717CFD5558" modified="2024-11-27" version="1">MVTRRWRGSTSTLTPFSRPFVLSKQKERPATNLLRKRQSGWSENCVRERSFVFRGIAEESLVGMPCYVVDSKRGNSNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWV6</accession>
    <name>A0AAV4XWV6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 2 subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 2 subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EIF2S2</name>
        <name evidence="8" type="ORF">CEXT_36521</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018338">
        <property type="protein sequence ID" value="GIY98798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor IF2/IF5" evidence="7">
        <location>
            <begin position="190"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY98798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="324" mass="36896" checksum="2500DA75A29CA473" modified="2024-11-27" version="1">MEENSKTNDQDFPLELKDFVGLKKKKKVRFSAVGIDSLNISNKENDTIPTNNTAEPETTNKLSDLEDDLNFQQLKKKKKKKKIPEEFITSTKENDIMPAEDIAEPEILNKLSDIEDDLSFQQLKKKKKKKKSAEELSSPVINTASSTIEICDILPASPKDDDTDYTYEELLARVFNIMREKDPNIDNVSKKKLVMKPPQIIRIGTKKSSFVNFIEICKLLHRTPQHLQSYLLVELGTSGSVDGNNQLIIKGRFEQRQIENVLRRYIKEYVTCHTCHSPDTMLQKDTRIFFLQCESCGSRCSVASIKSGFQAVTSKRAAIRAKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX66</accession>
    <name>A0AAV4XX66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_192771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018354">
        <property type="protein sequence ID" value="GIY98888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11902" checksum="FE5FD8CC30B6B522" modified="2024-11-27" version="1">MSETCKKIAHLFSRAHSSTCSSIALDRADGSKRHPLSKERRKKNKKKLKNKKGVLGIVVEKGKMQAIMTQCNVPLRCIIQQVDHFHSQGYSIGFDGAYKRFIRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXI0</accession>
    <name>A0AAV4XXI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_23261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018311">
        <property type="protein sequence ID" value="GIY98580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8408" checksum="37DB2A312D01BEFF" modified="2024-11-27" version="1">MEYTHSTPLGLVLFRSDLERFSCRHVPFPPHLSLKSHLLDVCMHGTTGHDLQRHNKAGENDENPKWKSGERSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXL1</accession>
    <name>A0AAV4XXL1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LRRNT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_779571</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001078">
        <property type="protein sequence ID" value="GIY99717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000372">
        <property type="entry name" value="LRRNT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01462">
        <property type="entry name" value="LRRNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00013">
        <property type="entry name" value="LRRNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043719334" description="LRRNT domain-containing protein" evidence="4">
        <location>
            <begin position="39"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="LRRNT" evidence="5">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY99717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="18895" checksum="8EEA115008F36F25" modified="2024-11-27" version="1">MQCNIVPFSDTARAKPGNGSSGMTFLLLLLLLPPAALPCPAPCACEGGVVDCAGQRLGQVPRDVPSDATTLLLGSNNLTDLWGQLPPAAPSASRPLPQPAEAAGPRAGVPQPERAAAAGPVAQRLPHPLQRRVPGHAAAAHPAHEPRPDQVHRGARVRRTPPPRHPPPLAQPPQRHLPRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XY83</accession>
    <name>A0AAV4XY83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_280061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001122">
        <property type="protein sequence ID" value="GIZ00121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XY83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14434" checksum="C2126563A58EF739" modified="2024-11-27" version="1">MVNNRSGQGVSLRTNGDSWLLIPTVADSVFSRIHHEISTTRQQLKVKESLSSKMYTDLLQFHSKKKSHPQLASETDPHAAKMGEAQSYQLLDVVVKIISIDLEEKIANHAILDVPSVSFPEEPRGQIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2Q6</accession>
    <name>A0AAV4Y2Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Homeobox protein engrailed-1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">eng1a</name>
        <name evidence="10" type="ORF">CEXT_229331</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the engrailed homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018574">
        <property type="protein sequence ID" value="GIZ00671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050720">
        <property type="entry name" value="Engrailed_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000747">
        <property type="entry name" value="HD_engrailed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341">
        <property type="entry name" value="HOMEOBOX PROTEIN ENGRAILED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341:SF6">
        <property type="entry name" value="HOMEOBOX PROTEIN INVECTED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00026">
        <property type="entry name" value="ENGRAILED"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="9">
        <location>
            <begin position="81"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="6">
        <location>
            <begin position="83"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIZ00671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19403" checksum="13F42FF65783B62D" modified="2024-11-27" version="1">MSYSANSGNLAGGPHERQNEKLNRQKNKIKFIQKRNTSTCLRMARTAVDGDLVFQDFLPQTTLKRDCPRSRRQSRKGQTTAEEKRSRTSFSHSQLQKLRAEFLANQYLDENRRQKLAKELHLNELQIKIWFQNRRAKMKKNSSFNDPLIQQLKEHGLYNHSTNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YGG9</accession>
    <name>A0AAV4YGG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 2J2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CYP2J2</name>
        <name evidence="16" type="ORF">CEXT_717921</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019310">
        <property type="protein sequence ID" value="GIZ05395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YGG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF375">
        <property type="entry name" value="CYTOCHROME P450 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIZ05395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="425" mass="49285" checksum="02C332DACCB4BF28" modified="2024-11-27" version="1" fragment="single">LRLGSIDIVVLTEYETIKEAFSKDAFMGRPPDLPFELSKETLKTEAFNGMPWKEQRRFSLHMLRDLGFGKTRLEEHLKEEILELLEQMSENVGKPVKLSYLLAPSMSNNIASLVFGKRLKYNDPVRQNLDRQIREIGRLAGAVSWQLFFPWIRAFVSKFNIGDNGKMVRLFGEMKDFCRKQIDQHEATLDPNNVRDFVDGYLLEMKKKGNDPKTTFRKEVLTDLSRAFFGAGSDTVRVTVDWMMLISSAYPEVQKKIHAEIDEVIGHERFPTWQDRLKMPYTDAALAELMRWKTIVPLNIMRYTLEDTELNGYFIPKHSRVLAVIWAVDHDKKLWGEDVHEYKPERFLSEDGKKVVKPEYAIPFSVGKRSCPGKSFAEVEVFLYITAILQKFQISAPPGKDIDLEGKLGISLQPKRQELYLKRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5H4</accession>
    <name>A0AAV4M5H4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_330511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001895">
        <property type="protein sequence ID" value="GIX67702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5H4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8183" checksum="DA787B4F74B8CDE8" modified="2024-11-27" version="1" fragment="single">PTTFRNSRNNRFSRTEDFKRQVEKRLLTIVQPADETSESYIQDVLALCRRGNMSVKDEKWPIFMKGFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBR5</accession>
    <name>A0AAV4MBR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_260336_1</name>
        <name evidence="1" type="ORF">CEXT_537171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001943">
        <property type="protein sequence ID" value="GIX68264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF5">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="272" mass="31334" checksum="E619B04744D9903D" modified="2024-11-27" version="1">MIGIAEDDKKYLKFLWYLDDDNENFKIMQMNRVVFGCNCYPFLLSATLKYHIEKYSETNKSCFEMLNSSLYEDDLCHDADDVESAFNLSSDAVSILSDRSVLSTAAKVFDPVGFLSPFVVRIKRLMQEIWERGLDWDSKLPEDLESKWKKWFAEIEVLGEMKIERCYFSNVIGKMDSVEIHIFSDASIVAYGAVAYFRNVNLRGEVSTSFVMSKSRISLLKKLSLPRLELMGALIAARLWKYLSKLFCGLVDRGVFVDRLRNLFVLDKGFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MC93</accession>
    <name>A0AAV4MC93_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_560521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019648">
        <property type="protein sequence ID" value="GIX70087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MC93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043887331" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9280" checksum="F04395DCA50C8B4B" modified="2024-11-27" version="1">MRAPHAVRVSSKMVCILIFATLYRDAAAVFRIQPSSSKKICKHLMMQYRPVWLHRLAYNRVSALPLESTFPNPKCIPAQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHD2</accession>
    <name>A0AAV4MHD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_740381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002266">
        <property type="protein sequence ID" value="GIX71919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9226" checksum="2D528DC0ABB4753F" modified="2024-11-27" version="1">MQPIKMHLSWPTAVTDWERDTDTSFHQDVRKELGIDFSNVIDTLPFADTQGEDVLTIHKNPFCCCVKLKISAENYFLLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLC5</accession>
    <name>A0AAV4MLC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fibronectin type-III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_133242_1</name>
        <name evidence="1" type="ORF">CEXT_715651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002400">
        <property type="protein sequence ID" value="GIX73312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11058" checksum="4DCD713C338B0CCD" modified="2024-11-27" version="1">MFFFFFHQIPCPPLSIWVRPDGSTRISSDILVAKGRGGEEVDVAVITKNPDKRPVVVVQGEAQGVEVKGLEPGAEYWVEMTPVQGRPFNYTGSFKACESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNC6</accession>
    <name>A0AAV4MNC6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase 6 regulatory subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_147812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019996">
        <property type="protein sequence ID" value="GIX73854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX73854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="784" mass="88414" checksum="5EE527607CFDD434" modified="2024-11-27" version="1" fragment="single">MFWRYNLITGSCIETLLDKENVTLKELMDEEDILQECKAQSKKLLDFLVRPEILNEMVTLIIEEPKDDGEERMRYRYANKACEMLTFDIAQINDALVNDETLLVKLYNFLTTDEPLNPLLASFYSKTMGLLISKKTEFMYEFLKERDFIALILKHLDTSAIMDLLLRFMVIENNEMRTIIIKWLDEQKLIQQLISRIDIEYGEEFNCNASNALCDIIKVSREQMSLLQEKAEPNPLLETIESVEVISELLNHMFKDVTKESAIVNGILVLLSLLVFKKQGPAGIQQMPMNQGEGLQADNAPSCFVSLFNRNSETEQITALDVERLERGVSNVLTAITPRLEDFHNLLLKPPVKPAITFTIGCLDPPLGICRLEVAHLQTALLYTNNQSVNAKLASLGTIVVLLDMFFKYSWNNFLHTQVEQAIGRIITNPPNIDKEGNKIHLLLDQILTQYKITVKILECFDEEVAKSAPGSHRKGYMGHLTKIANHLDQNAENGINSTFIQEKIKQLSDEHQKKWEEFVSEKLIEINKKNRIFTVNGPPMSNSSADEETIDFRNLPFAKGTSVHLTFSDNPIHEMTSNFVDQFGFNDDDFEDAHESLIYARNSINPSPNFSIGEGNSMRSSELFEEVCNAKMNPDGDAVLWSDRENPTTFTSCFRLNKSVEENSSDSDEESQVFESENTAITLNSEEMKMDVDSQEPILDGVPMDVAPVTIPNPWETTSSGGSSDDANWADFSNFGSFDPPADQTDDIGSSVSIAMETSDVMSEKCAVDSSSVLVSEAVCDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZR9</accession>
    <name>A0AAV4MZR9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">atg2a</name>
        <name evidence="12" type="ORF">CEXT_806231</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020257">
        <property type="protein sequence ID" value="GIX76499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX76499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="25878" checksum="71C0FE0BFD4CC111" modified="2024-11-27" version="1">MNFKNLRDKIVNYLIRSYLGDYVEEWLLERITLGFRSGICNTENIKLNIEGLNAKSKEYKLPIEFVACSIDVLSTQFRLKGFAATSITAQVKGLKIVVQTKERHEDDIMLSSMFDSMMTSSFKLAEDCLNSKTEDNEDCDDFDWPNEGIGGVHRVAKVINTVFQNLEINFIDTSLKIEYVPDAGSPGRALEIKIASIQFLMKLVRVILFLKMISLFLYQKIILLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N1S6</accession>
    <name>A0AAV4N1S6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_116081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002812">
        <property type="protein sequence ID" value="GIX78036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N1S6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11204" checksum="90BC0D6F52FB83A6" modified="2024-11-27" version="1">MYGSKKKRISPPKPLHGSIHEMDQKFVDLGVLGIFCGGIHTHTLHQTLLKTNQRKNEQEKGNKMAKRINKRATEMEPSKCMERRKKFPPKTTARVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N360</accession>
    <name>A0AAV4N360_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_486241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020443">
        <property type="protein sequence ID" value="GIX78848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N360"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11626" checksum="59FB1434EF426DD4" modified="2024-11-27" version="1">MKRRVPLICKQHTILDEWQRLNSTIVFAEKLDVYDNIRCAYVKKDTIVSNRKKEFTSQNSYKKQNRTPYVPRSHEFFLSSSNFNSSISFASESSRKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDM2</accession>
    <name>A0AAV4NDM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_727071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020685">
        <property type="protein sequence ID" value="GIX81509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12487" checksum="D9B0FF1F32632000" modified="2024-11-27" version="1">MPIAATPPQRTYMGEVLRRQAPKCGCETFTQTVGAINYKAIKRKFIEMFFETFFREHIETIKHSVIVASVKEKLRIYTNHFKVQSARGGMATRKNIPPVFPKIREKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHP3</accession>
    <name>A0AAV4NHP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_10291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003414">
        <property type="protein sequence ID" value="GIX84301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13642" checksum="30BBB0DDF619EE0E" modified="2024-11-27" version="1">MEAVMLINILCQTFIGITIKATKIQLIKTSCCDPKHILSKHAWRAPKKVSEKTPEGWQAKTDYMDFCSLNQTCVSMGDGQPGRLAFSGFAAIIYQAPRKRRSDTPRKNGISIDAKYYQEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMM1</accession>
    <name>A0AAV4NMM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_679291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003467">
        <property type="protein sequence ID" value="GIX84971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12081" checksum="A25600CDDE73715D" modified="2024-11-27" version="1">MDGKQVAPNANNYCEECIDVNFKALNVLLLTRNLVKIGTSKRPMLFEHFFHPFENILKDKTFIDESKVSIASFVRGDSTIRPIAERDDYSFKYILAKTGKWECMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMZ5</accession>
    <name>A0AAV4NMZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_741711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003442">
        <property type="protein sequence ID" value="GIX84612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9321" checksum="1EFCE090A1B2E338" modified="2024-11-27" version="1">MTYKIFPLPMLAQTYSDALLRNLFIGCLSSFPTITPYFCRSFSERHPDNFACPLGNLAGQQCAAGPSSNPKTKEMSPEASVFTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NN69</accession>
    <name>A0AAV4NN69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_150961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021120">
        <property type="protein sequence ID" value="GIX86221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NN69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10852" checksum="1C373B98F27F8C13" modified="2024-11-27" version="1">MGVHKNSESAPLYGSKKPSKRNESAVSSAEKCRTLCANKNRIHRGYNRKSEAMPEIKRLPGTCKFRVSQFEKSSDKPFRLARQGSPRGVAPHVSLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTW1</accession>
    <name>A0AAV4NTW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_203031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021304">
        <property type="protein sequence ID" value="GIX88216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10852" checksum="9F8FC3220D6CDE8D" modified="2024-11-27" version="1">MGTSVLGSLLNLKKLNEQIRCYSEGGRSSYCICILSSLAFCTKILQDKLLGLKSRAFPILSIGFANRIRFKILEVCCCKGQKTPTNRSTSRPFRKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NU44</accession>
    <name>A0AAV4NU44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_785421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021305">
        <property type="protein sequence ID" value="GIX88243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NU44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11493" checksum="5BA60B45D73C9AFF" modified="2024-11-27" version="1">MGSYPLFKYRRVIKEHMYKKSRPNEADQIKEKCWRKSLLQHPAAPRRHAVGAFGLETGNRNLSWLLVENKAFCNHRRLEPLNVTLMVLFYSDFWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P058</accession>
    <name>A0AAV4P058_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exportin-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">XPO6</name>
        <name evidence="8" type="ORF">CEXT_126471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021500">
        <property type="protein sequence ID" value="GIX90391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P058"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040016">
        <property type="entry name" value="XPO6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21452">
        <property type="entry name" value="EXPORTIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21452:SF4">
        <property type="entry name" value="EXPORTIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX90391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="729" mass="85355" checksum="76938123DD71AC2B" modified="2024-11-27" version="1">MGCINEIMSKHCIPADYEGFLLQVFQDTFHLLQNLTKDNTKNASRNILAEVDDVYVEKFTDFLMLFVIHHLKRFESNAQFPILEFLALLFKYTFQQPTLDGFYSCLDVWNVFLDYLSYKLKNENNNYEMTLNKYKDVLLALSQEILRKLQFRYNQSDLEELDDEDLNDDCFTEWQSFLCQCLEIVSKVSELLPIEIFHLVFSIFEENLRIYFDLEQFLKPSLNNSPLELNVCGENECRRLHCSLRDLSSMLQALGRLVVYMIKTAAPLVLKVDFIEVHAQILATLKAFCYWLTQYVKETKDGNSESSIEKIIAEIAIANIKKRKTQIVVYRSMSNVLVLPWNNVAVDAQQLWPIRSSQHDLLIQSLCEPLRTACSRPNFFQDKLIQERSKPDILWVLQVMCGLIENVSDGSTRTKQVFYKSLQSTISFVESLFHLYLQHSDVTESILEFYLCSSSQLFGIQSRPSICAKNYAEFLDFIFHRKNQVMEFTLNESSSGCKVIEKLLQLLQQVVQEPSSHFKAFLPSTIELCLGQIYPFIAERPSSEVKPPLFELLHNILLHNYRYFFKVNVVNSLGESGNEKIENEQHFTKIMEAYGQSFLQPDIVLFKQNLFSLETLNNKWKLFYKGYFKSVMLFHFLSLLLKTLIYRTHNLLKEEIISTIYNMALVDFNCFYTVFLQQFLQSMENLDTNQKSSLLRNFKRDTDLHSFAESIQRFVSDLRYYCLCTNTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5Z8</accession>
    <name>A0AAV4P5Z8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_551471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021507">
        <property type="protein sequence ID" value="GIX90582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5Z8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831335" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9633" checksum="F08FA585D179CBF7" modified="2024-11-27" version="1">MLKTILFAFRVLCSRFGIVVWKRKGDDELGWSMELHGGGYGLSIRMLLNNSDVRHESRPIPLLKRYYTKRSDPFNERHFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PC90</accession>
    <name>A0AAV4PC90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_442701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004463">
        <property type="protein sequence ID" value="GIX95012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PC90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF261">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14859" checksum="282478E7B841FF0C" modified="2024-11-27" version="1">MAGENNEDDTRPFLLKLPWIDVLFCQVFSRLKSLSVACIYGITDKSLVVMAHTLKCLESLNVSGCWRITDYGMSLVGEYCRALKSLKVEDCRGVTEYSLMTLRFEYVLIESRKIIVWVLYENYNYKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PG87</accession>
    <name>A0AAV4PG87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_221571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004639">
        <property type="protein sequence ID" value="GIX96377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PG87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10585" checksum="F938DFC3FCE014CB" modified="2024-11-27" version="1">MADLNASVLFARTPNMFIYELVKDKNKNRKKDVGGSQKYHQRDPNNPSRLMIDLIYDINILNETKIVPKFVSAIKHALHSVENLIYSNKVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHM7</accession>
    <name>A0AAV4PHM7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hexosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">brn</name>
        <name evidence="11" type="ORF">CEXT_370491</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="BPLR01004572">
        <property type="protein sequence ID" value="GIX95888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF349">
        <property type="entry name" value="BETA-1,3-GALACTOSYLTRANSFERASE BRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX95888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="344" mass="40867" checksum="102DC3F81FE04821" modified="2024-11-27" version="1">MEDVLIALKNNKQPPYKPINEYNYSYRINNNKKCLQSFNNDYEKVVILYVIKSALPNQKKRDAIRKSWGWENRFSDVIIRRIFMLGVSTDLLYQDSIDEEYARNKDLVQVEFIDSYYNNTIKTMMSFKWVVENCPKAQFIMFADDDMYVSTKNLLKFIRNPFNKRVGFRKKRDLSYTIWSNENSIRPVFESNLMLKTKKANFFNRNLFEFDPVLSAFDGRLFAGHVFFSSPMRHRSSKWYVSLAEYSFSKYPPYVTAGAYVVSFPALVDLYYTSMYTQSFRFDDVYLGIVAKKCGISPLHNEHFYFWRKPYREEAYSNVIASHGFDDPDELKKVWEEQRSLGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHP5</accession>
    <name>A0AAV4PHP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_805131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004575">
        <property type="protein sequence ID" value="GIX95903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9246" checksum="F47C36FF4B4809D5" modified="2024-11-27" version="1">MKTKDGWLEFHVQWIRWKEFSFANYSHTKKEEIEVSSCKGLCKCGPFRSSEGNPFFSLQSSLLEVQELNPFRFILVHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PIQ3</accession>
    <name>A0AAV4PIQ3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_505061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004657">
        <property type="protein sequence ID" value="GIX96514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PIQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10144" checksum="3A0145358C6B62D6" modified="2024-11-27" version="1">MFSNDIREKSNNCVYITDLEAALARLQSHVFDTVRRLLLCVYSDSLEDLDWESACNLYAAADKCDVNSLKYKCVLYLKQNLKCPTVALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW13</accession>
    <name>A0AAV4PW13_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein anon-73B1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_39495_1</name>
        <name evidence="8" type="ORF">CEXT_715131</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0239 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005037">
        <property type="protein sequence ID" value="GIX99372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009621">
        <property type="entry name" value="UPF0239"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14409">
        <property type="entry name" value="MANNOSIDASE, BETA A, LYSOSOMAL-LIKE, MANBAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14409:SF0">
        <property type="entry name" value="PROTEIN MANBAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06783">
        <property type="entry name" value="UPF0239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX99372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9708" checksum="EB40369965161E66" modified="2024-11-27" version="1">MADFVDELLRYGLFFSAIFQLICIAAVIFIPPREESRDGGDSSDEDGLPDGPIHQPSHRHHTHHVSRRNRQEKRSEDKLSLLVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2K9</accession>
    <name>A0AAV4Q2K9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kin of IRRE-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_18832</name>
        <name evidence="1" type="ORF">CEXT_418341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005677">
        <property type="protein sequence ID" value="GIY04163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2K9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16115" checksum="6D0997DB31FCCF80" modified="2024-11-27" version="1" fragment="single">MSLGLTVRGRGDSKTYTFVIENEKGRESFSVALEVREPFLLTMMIGGAIVIFLSGFKPAPESIVENGCPDNDRADLTTAKTVPYCTNPIIKGKIATIAEDPFYKDGKKGAVKFMEGTNGIRSKPDLPLSGNVGLEYSTSSFEDRRAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3U0</accession>
    <name>A0AAV4Q3U0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_553621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005484">
        <property type="protein sequence ID" value="GIY02690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3U0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16747" checksum="D0D21B45461CF74F" modified="2024-11-27" version="1">MQPLVNTRYIGGCLNLNPPCHHNPEREQLISPISFLNPMKLVSVTYLSLIAKAWRRLVCRLIKWRCSVQNSIRDSNPTPSCIGMQTVLAFYRSFPNNEKHCLSFHNFDLLRNKNPRRYKASHVSALNLIDCDINTVPPLQEKFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QG65</accession>
    <name>A0AAV4QG65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_401111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006073">
        <property type="protein sequence ID" value="GIY07242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QG65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8537" checksum="64591329D72D53F7" modified="2024-11-27" version="1">MQPRYWLDYLRKDTMRFAWSTREKCDSFEKQHLPINDGHVDTEEVLSISADAQLLTYELNELSLSITTATANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QH87</accession>
    <name>A0AAV4QH87_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RAP2A</name>
        <name evidence="13" type="ORF">CEXT_237991</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Recycling endosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01006103">
        <property type="protein sequence ID" value="GIY07415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QH87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000189">
        <property type="entry name" value="Member of ras oncogene family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="11" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY07415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="20950" checksum="71438393BD3DADEB" modified="2024-11-27" version="1">MREFKVVVLGSGGVGKSALTVQFVSGMFMEKYDPTIEDFYRKEIEVDSAPCVLEILDTAGTEQFASMRDLYIKNGQGFVVVYSITSHQTFQDIKNMKEQIMRVKNTERVPILLVGNKVDLENQREVTTLEGMGLAQLWGCPFMEASARNKCNRKAKLLLLCYSLIVIKQLATALFLIVDQWPDAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHB9</accession>
    <name>A0AAV4QHB9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL6</name>
        <name evidence="7" type="ORF">CEXT_450931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="6">Component of the large ribosomal subunit. May bind IPO9 with low affinity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006331">
        <property type="protein sequence ID" value="GIY09103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHB9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13156">
        <property type="entry name" value="KOW_RPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000014">
        <property type="entry name" value="60S ribosomal protein L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000915">
        <property type="entry name" value="60S_ribosomal_eL6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041997">
        <property type="entry name" value="Ribosomal_eL6_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01159">
        <property type="entry name" value="Ribosomal_L6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY09103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="19312" checksum="C6C823B88AB1383D" modified="2024-11-27" version="1">MVAFKNHKRYLRGSITPGTVLIMLAGRHRGKRVVFLKQLGTGLLLVTGPYQVNGCPLRRVNQIYTIATSTKLDISNVKMPEHLDDKYFRRKKPQKKSKKDEEEIFETKKEEYSVTEQRKKDQLEVDRQVLDVIRKHPEKNTMIQYLKALFYLQNKMYPHKMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHX3</accession>
    <name>A0AAV4QHX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_636631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006143">
        <property type="protein sequence ID" value="GIY07706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12645" checksum="056E497A96BE3994" modified="2024-11-27" version="1">MKQNREIKTLTEIRLTFTVRKLSKTITPVKYCTWKSKRIGGGNLLRLMGFHEQQLTQLSLAGGHFSRCRTQDDAVTTMPSRASKKRITTLNGSFSIIHNNNNLFYAIISTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QK70</accession>
    <name>A0AAV4QK70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_470211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006258">
        <property type="protein sequence ID" value="GIY08486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QK70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9535" checksum="884047B5C9442761" modified="2024-11-27" version="1">MAYLFGVRHLFHYAARQPPIKGAPSTYLAVSLRGALACHILSLYLLFPSPLSLSFAPELPHPSPCLSLIRSCLSLHFRAKAMASRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSW4</accession>
    <name>A0AAV4QSW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_149791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006776">
        <property type="protein sequence ID" value="GIY12352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9828" checksum="AC2E40B6B61E6A1D" modified="2024-11-27" version="1">MATYLHNSISGQPLLNFHTNTCQAKQRQLCIRRNLQLRSAARTPKGVKSCANRTSIPKPGLISSYFHYANVLELASGGTLKGPRNLMDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1S2</accession>
    <name>A0AAV4R1S2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_355921</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007053">
        <property type="protein sequence ID" value="GIY14261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1S2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase RNase H-like" evidence="7">
        <location>
            <begin position="90"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY14261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="254" mass="29469" checksum="098BA96488EA2E9B" modified="2024-11-27" version="1">MSSEPYRHCIQRPIKDAEKHAVAFEACATLIYHLNKTIKPDPSNLVPFVKTIQNIAASLQRTFEEAVKEFEISKSDIFKVSLSAIDDIMQFRVKTNTSKFAIAATLRQTDPPIAFFSKTTLNLTVEKKKHMLLCNRCVFGDIIFGEPFEVFTDKRSVSFMFDQHHARKIKNEKIMHWKQELACYKFNIIYRPGSKNATANAFSRINAAINPEVNLKQLHDVLCYSSVVRMYPNNTWTERKTFLFHWKILEDLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2T9</accession>
    <name>A0AAV4R2T9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_25141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007116">
        <property type="protein sequence ID" value="GIY14621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2T9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12009" checksum="F4C94E4986A6E819" modified="2024-11-27" version="1">MHSSKPFLRLPLSMVESVNRSFIFINIFYRSTASSYNGCQMFFCPQASPFRLFARAGLVIVKNPTVFSRMMRGGMAHFIPPRVTFFHSSSKTINWPLPMHSNGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDE6</accession>
    <name>A0AAV4RDE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_354601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007578">
        <property type="protein sequence ID" value="GIY18132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8444" checksum="C8C2A99914FDCB4F" modified="2024-11-27" version="1">MPQKSGVQRIFPTCENTCTDKRTEVRDDSNAGDNRHRFTTTAGYAVGLPLHLANIRRNSDIAFQIGVFSSLSLVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RG67</accession>
    <name>A0AAV4RG67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-directed DNA polymerase from transposon X-element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X-elementORF2_618</name>
        <name evidence="1" type="ORF">CEXT_316631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007890">
        <property type="protein sequence ID" value="GIY20470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RG67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="28723" checksum="DE65C5E8F8AC5B73" modified="2024-11-27" version="1">MINAFNKASTQHRLHFNSKLTPEIKNKIKLRNQIRRTWQTTKDPSLKSQLKKLNNTIKSLIQTHKNSKWEQYTDSLSDNNKKYWKKVKSMRAQHTNIPPLEKDADNIAISPADKAEAIADCWKHQFEQNPNMSHEFTNNLIASETNNYLATPHVNFNYNITAQEIIEFINTLDPHKATGHDKINNNMIRHLPLKFIWWLISDKPIVPWSISGRHNSLNVAHHLFSEIDIHREYGYGRRITVYHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RN36</accession>
    <name>A0AAV4RN36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_194491_1</name>
        <name evidence="1" type="ORF">CEXT_121491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008049">
        <property type="protein sequence ID" value="GIY21695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RN36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.60">
        <property type="entry name" value="Spidroin, repetitive domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043070">
        <property type="entry name" value="Spidroin_repeat"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="456" mass="51157" checksum="8A6039E66E04C6DA" modified="2024-11-27" version="1">MDKGIQTTRHRLSEIYSVPLDEVISFNLFWDNFGEVNISLLKNIIHNTPTATTVLKEKESMTLTSIFKKLLTYNLLSSKLFIRSFNNNTTIMRASKYAFAIANSVSDVIKSTSVSTELIQAFDISFFRLQRHTSTGTYASIFSSIISDIFNQKNILTSTKLQPLSINVSYAINSALFSVSSMKNFRGKFFSKKELKMKLLLHQLKLPLECSESRLHAIKMAEILKSQLKIDMEPFQSLIESYNAVLSSLHKRSDVEQGILEIASITSGMLKNLNFTDPSEVISQAVVTSNKLNSAISENQLARKIASATTEILSKQRLLNTSRLVTQAAFTSNIMIKSIANAFEVCSNDGSRVKKVETSILGDETFNKSLYYNLQTQTPLGFFLQNASHNEVTVLIKAMLKFLISALKKTPSQDDDELLHSTLYEMFLKEKAENHSNVNEAIVSSVIASFLKQKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQ58</accession>
    <name>A0AAV4RQ58_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_672141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008103">
        <property type="protein sequence ID" value="GIY22098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQ58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13585" checksum="4C616452F2F91E52" modified="2024-11-27" version="1">MRRSFLHPEEKLFVFRWGNFLEDAEQRRDRERGCSIASSRLAGTPLARIGRYIDPCPKQAGCFLLFFLGALRVDRAKWGGRNKWDWMMGLPFQEAQQTDISFSRCILRQGLQTFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRM3</accession>
    <name>A0AAV4RRM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_407901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008263">
        <property type="protein sequence ID" value="GIY23334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="19960" checksum="E419FC5E8320999B" modified="2024-11-27" version="1">MNEESSGSLFKLLCSMNAADKDRDFVVGHFFNKEGSPKKIPHILVWNLRNTLLLELLKIGEARKENGELQVKADADVSDSIQTMKFFNADSSVIESGTNYHSSKVCSNSNRWNARKENFELQVKADADVSDSIQTIKFFRADSPVIESGTNYHSPKSVVIRNRITLNRRAYLKREC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RW93</accession>
    <name>A0AAV4RW93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_587111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008435">
        <property type="protein sequence ID" value="GIY24656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RW93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12668" checksum="D51C9143F650E368" modified="2024-11-27" version="1">MLSGGRTHGRDLQTELFRLVHPPWGKCISCHHRSPSPVLRTKNTIDRSTKRTQAGERLRHKNGPVLGLKGTEPQAAIAGLLWQLPLSAPGSEGETSGPVIVDLGVMESGATSRTARKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RX95</accession>
    <name>A0AAV4RX95_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_187591_1</name>
        <name evidence="2" type="ORF">CEXT_588411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008465">
        <property type="protein sequence ID" value="GIY24905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RX95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="42805" checksum="C90F1AD74D7D1401" modified="2024-11-27" version="1">MELIAFFLMIFGIYQPVPKKPSTLPDRILLTCFKLYQFAWCSSLCYLLIMINSAVFQVKIFLVHICDVLLVNVLWYILQYRLKLLEMCIKKQSNNWRTYPTMSCRVKIITVIFFHNCLINTVLNVAKMLTVSKILNYMEAAMTFGYYPLNRIAPNGEEFLIKSAIAIGMIIFYAFPPVAAVKCYLTLLPQLLSDSKLLRFAENSFQTDLLRSKDFLLDLTKAVDFVKGSQFRHFPVLFILISFWATGIFYNLTKILYDPTFRDSYNLMSAIFNVAIYSVQYLLLLALASKLPMALSDMRSDLLRNAAIHRCIFSEPRICRCQPAHVDPGDLQRRGHSFASRLDRTQKRSLIPVSIGVLATYELLIVQILER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZA8</accession>
    <name>A0AAV4RZA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_30661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008767">
        <property type="protein sequence ID" value="GIY27075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12512" checksum="01D27C2ACEF26FFE" modified="2024-11-27" version="1">MNKGSSFTVILLDHVNNEARILVGSKLDSLICHLFYEVVAEVQLHQDRHSQIVLDVELPDETMVQVEVAGVVHLPVKRVLGHSGKGIVGQLQLVHVVHPGMQNRVQSRQVVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S257</accession>
    <name>A0AAV4S257_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_130911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008722">
        <property type="protein sequence ID" value="GIY26681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S257"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7160" checksum="B25E9CC3CA4AE462" modified="2024-11-27" version="1">MQQEISLLGLSVFCGYPYLNQTVFRAGPTNLVAGNQESGLISTSGSPSKVNRQTNLKSCVLGTLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S935</accession>
    <name>A0AAV4S935_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Pyruvate kinase</fullName>
            <ecNumber evidence="5 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">pkm</name>
        <name evidence="18" type="ORF">CEXT_743401</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 14"/>
    <dbReference type="EMBL" id="BPLR01009149">
        <property type="protein sequence ID" value="GIY29879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S935"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.20:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 18" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="16">
        <location>
            <begin position="6"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="17">
        <location>
            <begin position="139"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIY29879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="258" mass="28346" checksum="A160EA5FF1E1AD47" modified="2024-11-27" version="1">MISSFRIDEIIEASDGIMVARGDLGIEIPTEKIFLAQKMMIAKCNQAGKPVICATQMLHSMVSKPRPTRAESSDVANAVLDGADCVMLSAESAKGEYPIEAVTTMHQICNEAEAAFFYKTVITDLIYETPIPMNQTSVIAIAAVVAAMKSLAAAIIVLTTTGRTANVISKYRPRCPIFAVSREGMICRQSVLFRGVFPIHYTDERKPDWTEDVDSRIQFALEYAKRRKYLRLNDIVITVTGWCQGAGSTNTVQVVVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9V0</accession>
    <name>A0AAV4S9V0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor Sp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SP1</name>
        <name evidence="9" type="ORF">CEXT_197031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009033">
        <property type="protein sequence ID" value="GIY29180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9V0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000077">
        <property type="entry name" value="Sp8 transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF165">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="615"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="657"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="338"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="543"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="338"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="548"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY29180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="731" mass="76937" checksum="A592BE41ECD1A70A" modified="2024-11-27" version="1">MTSVASRKQQQEYVVPTSNSQDIQPSPLALLAATCSKIGSPTDEGGSQGASPVKVVGHNQVIQSGEIIATATGAHLVPFQPQTVGVLNPDGTVTQVTGVNQQTAAAGNVHVSGNVAALKSIPTVATAQNVASVTGQVFQQGTQLVAGNPGNITYNVIPAQQIQNIQIDGQDAIYIPAMPQTFQISGNQIIQAPTGQAFLRAQGVPVPTSVQNGTQAVLQGMTGAVAQIGGQNVTIRQGNVVQALQLPMPIQQTIPVQVPISTANGHTMLQTIHVPIQTMQGVPGANVLQSQAQPITLNVPAHMLSQLASQMGPLAQLAGQQGQVQQLQVATPVHMSQANSQAATSTTWTTSSGTSVNSSSEVTNASQGQAVTATTAASSANGAQQQQQQQQQQQQQQPMQLTSFQLPNGQVVQGQVSQIITGGGGGAWWQNSPISVQNLAGLRPANVIQVQGLPINGLQGVQVQGGQAQQIIANAQTLQSLGLGANVIAANTVPSATNHQQQMPPLSPIQTVHPGTQIITQQLQQDPNDPSKWQVVATATNPTVGTVNSSQQPTSASQNQAATSTTSTSTESPSSNSDISAGRRMRRVACTCPNCRDSDGSRNLFRNSESKKKQHICHVPGCNKVYGKTSHLRAHLRWHTGERPFVCSWMFCGEKRFQCAECLKRFMRSDHLSKHLKTHLTKKALSADVKSEGEITDDITPDSCDLSMSVDMDPDNDLSINENVVESSQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SCF7</accession>
    <name>A0AAV4SCF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_336871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009335">
        <property type="protein sequence ID" value="GIY31162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SCF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10304" checksum="4B0112F62E5BA8F3" modified="2024-11-27" version="1">MLLQQKVRKIIRLLNSSQIQGLFCRASVTHVPTDRILKAVRLSRKRMRHGTHDCPRKNPSVFSTKIPICQVICEGEESEQLNHFKSEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGT8</accession>
    <name>A0AAV4SGT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TSC22 domain family protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TSC22D1</name>
        <name evidence="10" type="ORF">CEXT_778461</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TSC-22/Dip/Bun family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009443">
        <property type="protein sequence ID" value="GIY32006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008284">
        <property type="term" value="P:positive regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21936">
        <property type="entry name" value="ZIP_TSC22D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.490:FF:000002">
        <property type="entry name" value="TSC22 domain family, member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.490">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000580">
        <property type="entry name" value="TSC22/Bun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047862">
        <property type="entry name" value="TSC22/BUN_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46745">
        <property type="entry name" value="TSC22 DOMAIN FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46745:SF1">
        <property type="entry name" value="TSC22 DOMAIN FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01166">
        <property type="entry name" value="TSC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58026">
        <property type="entry name" value="Delta-sleep-inducing peptide immunoreactive peptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01289">
        <property type="entry name" value="TSC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY32006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="19981" checksum="40D7C30A68DA6111" modified="2024-11-27" version="1">MNTLVQVSVVDSTQQQTKSVESKNNILHRRSNQDRGGTLPPQWDLSFSENSLLSVYCFIKNFIGSQTAPEKLPSEVGQEVDPSGGSAVPTGANTVAIDNKIEQAMDLVKSHLMFAVREEVEVLKEKITELLERISQLEHENDILRANASAETLKQLNSQSHKKSASGGNTGKSPPVTAIPPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SID1</accession>
    <name>A0AAV4SID1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PACT_coil_coil domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVEN_197882_3</name>
        <name evidence="9" type="ORF">CEXT_492082</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009740">
        <property type="protein sequence ID" value="GIY34193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028745">
        <property type="entry name" value="AKAP9/Pericentrin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44981">
        <property type="entry name" value="PERICENTRIN-LIKE PROTEIN, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44981:SF2">
        <property type="entry name" value="PERICENTRIN-LIKE PROTEIN, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="8">
        <location>
            <begin position="1338"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1027"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1473"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="264"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="326"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="422"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="652"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="739"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="833"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1127"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1032"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1043"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1473"/>
            <end position="1489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY34193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1524" mass="177525" checksum="F74B0F44E68E3404" modified="2024-11-27" version="1">MEAMEKQLLSNKKFIDEQAQEREQEREDYIKEITKMQDVVREKEKIQSNEMQLTKEIESLEIVLRARIEDHQNAMKKKEMVENDLRQSLDKIRDLRDVIEELEKTLDIKCKIEVELRQKLTALSESVDAHKKMNSVLDDGLSKSKSALLNGESMEQVENLKEQLASQSQEIEQMSQNQTLLHELRGQIHFLEAKVEQRARLLETMHLSSYTSPIQSDDNSPGGSQSSENLQLPCEDGYEMSPRSIHWLEIRRLEEKIGRLAHMDEELIKKNKELELQLKKMKNQQIESQHENAALQEKLSEQLFQISALKSHIEEQKHCFSTPQKSQAMNDRIEELHEAFENQLEENKRLLSELRVTQRALNSLESDVEKKDNLIKSLQSNISFMKNQAHQNPELKEKIEENLSSVTPDVNESTACFKLMLLEKNEELVEILKSEIVSLNESLESIKEQLRGEQNQVETLMEEMANITQDNKRLEQDYDTIQEMMQQKERELATLHEETDAQMKLEAEVECLERELEDQKSIELELRQIMRQMETALEVSKNTLKSENAQWRLRVESLEKAHCLEIENLKKQNEVLCRNISSSEVEDIDLVEVRKEILYDAGVAFGFHDSKAYGDLIYALLKKAVDIKLSQMVKKHEAFVKEINESWENKIKTEFNTKNYNLNSQCEELKKENLLLKEKFQDQNQRLSCEKDSLWQTKLKESEITLRQELETKYGVEINDLKCALDNVSKEKSSTVIKVKDLTRQLKEQKLKFQAHKNQLLKDFEDKIISAKREQEKLEGKQQTESIFKQEIERLQTELHSKLEKERMVEESHRQEISKLHKFFETRWVDEMKKIQEIQIEELKKLKDSKERNVEALCNHLFAQYSDKLKKLQEDYAAQLAEERKVFISQHKAELQNLQQALEKRFENEKQNLLEIKEKEMKNISESLEKKYSKKITDLRKDKSLNNHNMSSGKDSRNPWEEERLELISLHNKEIVDLKEELEKKYDMMLQSQMISHEVEMKSLEDAYSQKVEEVHELIREARRIASKSCHSDSGSNRTTTPSSEMSSDEACSSCQEDMLPGNKHILVNKIHQDGKRVLNLIESSLATTSTEREARLWIEERKWIVKRIQILTPEVVDNPTNLKLIISNIVDELLNARQKLINYNEEINKNEEKFSQLEQQLDTEHSKVYIIATNLSHQTKVIKELEALLNSRTSEIIELKKYFANVNSTQYQNLTGKDALSQNHSENLSSSYDVGCLRSADEPKSADKFSMFLPELDSLHLQKSGDEIEVTREGMASLPQLTKELDQYLDGSISPESLGQYSRNDIFSVREELMSKLSDKGPQASYEAKLHGLYWVYKRSMSYSKSLVYQKKYLLMLLRGFQVTEKVTEAWLHRMDNDISPRPQGDDTVINEPPLRGRSLFRSAALVAVAIQRMKFYVRRWRFLARIPSSQVVDAEIRTVFLGYSAFSPTLTPGGCNSSLLSLSSKATSISGTEHLSNSQSLVNSRPGSKTKEKYSTPDKRQLIEYVHRLETLQKHLGLDNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJJ9</accession>
    <name>A0AAV4SJJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_61661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009578">
        <property type="protein sequence ID" value="GIY33011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="14390" checksum="22C037624A6A7BED" modified="2024-11-27" version="1">MDMKRHFIMDMKRHSIMDMKRHSIMVISRPFILDFKRHFILDIKTHFILDMKRHFIMDMKRHFIMDMKRHFIMDMKRHFILDIKTHFIMDMKRYFLYIRMHIVFKHYNLKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZN3</accession>
    <name>A0AAV4SZN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TD and POZ domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Tdpoz5_39</name>
        <name evidence="3" type="ORF">CEXT_675091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010529">
        <property type="protein sequence ID" value="GIY39908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="298"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY39908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="404" mass="46827" checksum="CC24F5223D49A0E0" modified="2024-11-27" version="1">MNGKDTKWKLRIYPRGCKEENFIALFLCGDEDVECPEDIALNYKLEIVSQNKIVKSGNNIFKKKEIIWGFLEFIKREDVIINRRSEILPQDALTIRCTIRRNDDKDIEAGQFSALTDIKVTRRSFVWEIRDFSNLKTNKQMSVVVRSPSKEASIILKLFLFEVKYLEEVINIHICSSCEAINCLTLTFSLIDVEGNRVECGKTELLSDQLKEGTTFALQTSKLEIMENKNYLRKNCLSLGCEYAFSTGSISEEIESVLNFGADYRKEIIETELKPKALYEHDDLLDDLKSLYRDETLSDMELRTETETFRVHANILSARSEVFKAMFTTEMKETSNRHVYIPDVDNDTLRRMILYLYTDHLEGLEWESASLLYAAADKYAIHSLRKKCSVFLRNAFSFLMLVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T648</accession>
    <name>A0AAV4T648_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010729">
        <property type="protein sequence ID" value="GIY41605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T648"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16831" checksum="57114BBE0CF421EF" modified="2024-11-27" version="1">MLNPLLIPKQNAFSKPILIPKPNVEAKTNVNVKDNLNSKIQMFYSKDNVYSKIQKFYDKANVYSKIQMFYGKANVYFKIQMFYGKANVYSKIQMFYGKANVYSKIQMFYGKANVYSKIQMFYGKANVYSKIQMFYGKANVCSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7G8</accession>
    <name>A0AAV4T7G8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_79751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010873">
        <property type="protein sequence ID" value="GIY42608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7G8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="23109" checksum="F7372AF9BC0A2C45" modified="2024-11-27" version="1">MDSNCDTHRDNRAARERSTQAQVQGQQRRVTHQGQSPPPPPPPATEPPPTRPPPARQSPHLLEAGLRHVQAALLPGRGGRCSRGSAQGGEPSASAGGALCPQPPKGRLRGGVVGGRPSADAAQRREVAGGHLEQRQDGRGHGGVPPLRPTPCAPLLPPPPLLSPPPQEGGRGGSMGFGVAAPGSGGGSSRESVQEITARLLFMVIRWVSACPRSRPSPRRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGM9</accession>
    <name>A0AAV4TGM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_167191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011075">
        <property type="protein sequence ID" value="GIY44042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7595" checksum="A61B6110BDD87FCC" modified="2024-11-27" version="1">MPKRTTDLWGIGHGRLPDSLKDMVQQLRHALISADDNLKELGKSKKILKRQKVLNTGHIKLHMPSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNF6</accession>
    <name>A0AAV4TNF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_206031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011653">
        <property type="protein sequence ID" value="GIY47970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8890" checksum="AF1049132EA74C68" modified="2024-11-27" version="1">MAQLTFRIAIGSVYHSPPLRSKLLHSFSCTATTPFFHVRLSTRIGRPLQVCATLPLTLHPLCHYRLPRIPKGGHMVVEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQG0</accession>
    <name>A0AAV4TQG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_588981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011609">
        <property type="protein sequence ID" value="GIY47696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7848" checksum="30F289EAA057835C" modified="2024-11-27" version="1">MRANSRVFAPWTIASAAMDATDFDAEKDYLLFFASANTDESAKSAVDLHCCSLTLQPATECIAELSEASAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYB3</accession>
    <name>A0AAV4TYB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_27981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011828">
        <property type="protein sequence ID" value="GIY49398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24034" checksum="E1EC82F1ED196D3A" modified="2024-11-27" version="1">MDSVQHRASKIIIEQSPLSITTRPNRNVAYLLLKTDATLPPLNLLPEYLKNGRAQPDSKDPQLYHLIKISEYKINTFTLPERQSPPIVVTCRCSARNYISFNKRRYGCRRSHLSLRKAEIRLCFQCVLQLRHSKAIKKGGVKIEGFFSPARGGLFSHSEREGRRVRPLNYTRNKGHEVCNRLRLVSTFSSTGNPSPLHLSCVGVLIILDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZ17</accession>
    <name>A0AAV4TZ17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_361851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011995">
        <property type="protein sequence ID" value="GIY50581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZ17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12441" checksum="0E5A6890AA7746F4" modified="2024-11-27" version="1">MLEDPLLVDLCFNTHHQLLPNSPISRPSVVTEDLREPFLENPFLVDLRFNTLIPSSQDPRGCWRTLWWTYFNTHHQLLPNSPISSPSVVTEDEPFLGGPVFNTLIPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U707</accession>
    <name>A0AAV4U707_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_70111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012365">
        <property type="protein sequence ID" value="GIY53415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U707"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8123" checksum="333D93E5599F69FF" modified="2024-11-27" version="1">MVLFHPPPPSLVAGEVFISESFKSLKRDGAGVESDISCPECCDLAITRNGFWGGWNDRGEGDGWRSFAFVFYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAK0</accession>
    <name>A0AAV4UAK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_4128_1</name>
        <name evidence="3" type="ORF">CEXT_176471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012546">
        <property type="protein sequence ID" value="GIY54724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043966238" evidence="2">
        <location>
            <begin position="19"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY54724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="340" mass="37720" checksum="8955BB2DEAAE85C7" modified="2024-11-27" version="1">MLLSIQMLVHLSFSIVLADIVENRISLAIQRVHYAVDDHGIRANIHSNHVKFGNKFDTSSIGFGSRLRGWPRNKINTVVQKCTGDVQAPTPVTLVNQENFAPVSAVESPPAFSPLNPPQLSGSPQVYGIGTNIGSINKRKQNLKNMYYQKQLHQCPKSQSAFKPTDLTYEAERVSRPNPSNSFYPIKTHENLSAASSDQTGKGEIRDNPSNEPIGPPPPTISEIIPETSNSIAPQFPFYPQSAGLNFLQDSYPNNENLRWYQSLPPVPPPVNPFIMFHFILRRMNMNQRTSDGKQSGSFILPSNSQNAPNFNKDSAKLMKTSESGKSAPQNQVAYTNECI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBZ4</accession>
    <name>A0AAV4UBZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_772921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012624">
        <property type="protein sequence ID" value="GIY55266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10979" checksum="562744ECE99A4D03" modified="2024-11-27" version="1">MYASQNYGSSGGPPNKIKKITFKLSVFSVNRSDMKDQRQCNELLLFLILITGVRNVASAAKRFHKGTPSLSKVLPNLIFQRYVFAPNNTSFSSGERHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJD6</accession>
    <name>A0AAV4UJD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_289061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012979">
        <property type="protein sequence ID" value="GIY57867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12978" checksum="1A691EBDC2516E25" modified="2024-11-27" version="1">MTERLDLEKCSKNLYPKMEQPEWAREVRSTSFFFRVDSGGTMGSSPMSGGFLKATGFSPMEGLTDGDGVLERLGGFCSSCFSELFKKEVADSFLSLSSLPSCSSGDSGKCWREDWQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UN98</accession>
    <name>A0AAV4UN98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_541541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013178">
        <property type="protein sequence ID" value="GIY59204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UN98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21550" checksum="F0C042832E669851" modified="2024-11-27" version="1">MGLEACGWPLTFTFSITVIYMLTYESGFSSVRPIPFHRPKPEEVTATSVPPLTQEAIRRESKMLVIRWSSDNAEISRKAMSFPAAVSVLWPRCASVMEYPQHGLWAHYGQFNNSQDYKQYCSGHIRCVILFICQLRFLNECYFDLMGLQEHGIPEPPVVPSLHIQQYWNEHTLCCSNSTSNVESQPCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQE5</accession>
    <name>A0AAV4UQE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_79481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013275">
        <property type="protein sequence ID" value="GIY60070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="21177" checksum="73EB9490479823B4" modified="2024-11-27" version="1">MGTISIGHKNPSLQLKQRVQAVRPMSKGHEMGTQYFHRSENPSSDCSRPRRPVPQQEHLEQVLPEEQSHGRRQGPHHAQQGSLHPPEEEGHPQERQRQPLQGARQQAQAEVPAGHLRHHARRHTVAIQPHGVRHGIPAELAGIAPICGWLICLAHGDFDHIGDEEWTPVSGGAQLRHRLPLLGGDAAHHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UR28</accession>
    <name>A0AAV4UR28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_59067_1</name>
        <name evidence="2" type="ORF">CEXT_248971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013292">
        <property type="protein sequence ID" value="GIY60198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UR28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043641014" evidence="1">
        <location>
            <begin position="16"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="25258" checksum="58443936BAFE8C19" modified="2024-11-27" version="1">MKFLIILCVVGVAFALPEDACQRKCSEVCTSRYPTPQEVPETAEGLKNVCGYFSDIMPCIKEFVDKCGTLNADLFRGYVLDESIGNIIETTKAVCRPGSKIHKVIVEKLSCLKEVSEGEAQYCQQKEANTLRLLREHLGSEDLSPFRHVKKCLFPALSMNCYVGEIYRKCGSDAKDASLEFLEKFKILTNDCRKTLHPEFLMLLDLVKMLTKEEIYVRKFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UU66</accession>
    <name>A0AAV4UU66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_131281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013458">
        <property type="protein sequence ID" value="GIY61362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UU66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9991" checksum="BA771EAB952CA81C" modified="2024-11-27" version="1">MLQRYVELLALKHSLRPIEIGKISPQTATQCYIGGFAKKAVIKLRDLRLQQNEPPRVRQKEIPQLFSKSFNNKFSPGRFDHLNSVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY05</accession>
    <name>A0AAV4UY05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_123721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013668">
        <property type="protein sequence ID" value="GIY62811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20177" checksum="7FBBB113A90ADACF" modified="2024-11-27" version="1">MSGRLKSLSREGEIRQIGAGFIVPNGESEMTGTGAQKSVAKRFSRESIFGVLGCQSGLKGLSREGKSDRWVARKEESGIRCSKRRIRDDVRVGWRSENSPYVGYECRYNFIPFRPSHASIKAEMDCHRDGRKQDQEKKKKLKAGPARIEGAPGPRKVSRTLLRESILGFGDVRPVEKLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZG3</accession>
    <name>A0AAV4UZG3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_151021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013707">
        <property type="protein sequence ID" value="GIY63163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11910" checksum="5D5C3B4059F26F74" modified="2024-11-27" version="1">MPSNGIIMPFEGILTTLKIVDEKTRGRGERRRGRSQGSSSKPLSISFARFSVLCSNPHGTMAKRNQCEGKGGKPHPVAVVTYLNEKTTLEHTKLMLYQHAETWRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9E0</accession>
    <name>A0AAV4V9E0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_32590_1</name>
        <name evidence="1" type="ORF">CEXT_728491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014076">
        <property type="protein sequence ID" value="GIY66105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9E0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21640" checksum="456CD237FDAC231A" modified="2024-11-27" version="1" fragment="single">MVLVSVFLATLKMHQKKEKGSDSSDAIISLLPVLEMADCGSAEAIVKLINEHLDDAKDSRSVNGIVDFYITKESNRTLDILIRLKDPHDKHLFDKISELMKNEGYRYKSLQLLMNIVYRQPPWLYRIANHRIMNNLLNLLKTDQNAQNLLSCLFILISLLPVIPSQFGPFLNDTFEIFSKISFMGLKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJK0</accession>
    <name>A0AAV4VJK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_709611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014592">
        <property type="protein sequence ID" value="GIY69814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12774" checksum="DF764AECE39B3898" modified="2024-11-27" version="1">MGRGKESLSIRYVTHSKCFRSGFHNDVLSLPNNPPSSGKVPLLYGQQKVLGKTGARTRLIDCRLTGMQVPSYIAATPDYGFSGSSGKVIGDYYIWSLRFLLPIRHNQGNMITPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VM41</accession>
    <name>A0AAV4VM41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_643551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014783">
        <property type="protein sequence ID" value="GIY71307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VM41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10072" checksum="91C98F3F3C4B78D8" modified="2024-11-27" version="1">MFGVASSIFQPLLQSKEHINIQVYLDYLQFRYMNFFVCQTLDEVSMGNWTYTIYRIPLFLLSVSTNIYTLFRIPLYPLSGSTLCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUI1</accession>
    <name>A0AAV4VUI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_40399_1</name>
        <name evidence="6" type="ORF">CEXT_701401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM200 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015081">
        <property type="protein sequence ID" value="GIY73456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018787">
        <property type="entry name" value="DUF2371_TMEM200"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31815">
        <property type="entry name" value="AGAP005329-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31815:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 200C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY73456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="14869" checksum="B4A5294F15B7A6C0" modified="2024-11-27" version="1">MTAGFLFIIIGAGMATLGFYSDYLSKVEETRGNTTVWVKNESKDSHLGSLTYFGPVVMGIEVLQLGGSGSTPSVRSSKASWERFLSHQRSSEDAEDTRTAVTQELVNFSKYLQNNVDTNKIQLQPASSNQQITGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWS2</accession>
    <name>A0AAV4VWS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_716581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015269">
        <property type="protein sequence ID" value="GIY74886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12010" checksum="F5FE6B9C88A6FACB" modified="2024-11-27" version="1">MPKNCCEGVNQEVARSKLQRSCLGAQYPECRLIIRLGQVANDFNIFFQAIPLCSLWITSFYDDLFTVYISALISVRWFTTIARAAVFEKGISQWTLVDHTDTRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2I9</accession>
    <name>A0AAV4W2I9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_293011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015537">
        <property type="protein sequence ID" value="GIY76842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="402" mass="45602" checksum="DA41E221B9CFCDEB" modified="2024-11-27" version="1">MKNRIPSEPTMSDWDSIRSEAESGNGCRRIFRLEIIGHRSFRYIHNEWHKLTELLKFFDKFIERLKNGLKSDSLTALSFWIQKLAIPSITGRSGSNRFVWSFYCRSLSSDSKLDVIDKVDGHTDKTKLGCTLSADVQIQTSSHKPNMKVVSRMHVDMNVGAKIVRKERTCFSALLTPSENLLHVKISNSIVKTDEHHQEIPVFGKPHRKIESCYDGLHKPLGSYRVHHKQMHGNLVIVGNSKRLFNINVTHETSSLGSKESHKVSVTVFVKDNMVYGMNCSLNKTTGIKEHLSFEVKTHHGLIVKGACTKEGYIGFSENKEGKLSCEFSIIAPSGVYHMRKTIERRRYKKSHAISTKSVIEYQPTGGEKQSITCLGTVQKKAQEKLTRKLNVSQHIQKPIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W627</accession>
    <name>A0AAV4W627_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_337921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015728">
        <property type="protein sequence ID" value="GIY78201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W627"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13279" checksum="F2791BA0C7CAEE48" modified="2024-11-27" version="1">MDGFDEVDHHCLVTLCASSEIVFWFLRFRGGINVVKEIEFWDVWQESPSIASVEVFGGKKSMISISASCDPEIYLVGICDFSKLLLFELPSGEIGNNFRLCSRNRVLDKIVQEWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WA30</accession>
    <name>A0AAV4WA30_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_570271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015759">
        <property type="protein sequence ID" value="GIY78468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WA30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY78468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15173" checksum="DDF0116F15F8F4BB" modified="2024-11-27" version="1">MYGIAGCANTSASATLMTGPINVRNVVNALLTLAGCANTSASATLMTGPINVRNVVNALLTLAGCANTSASATLMTGPINVRNVAEHVRFSHTHDRNYRMWEHVRFSHTHDRPHKCTECGKCFAYRHHFKQHMSLHSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHI9</accession>
    <name>A0AAV4WHI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_43071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016235">
        <property type="protein sequence ID" value="GIY82326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9137" checksum="A561903286DB4458" modified="2024-11-27" version="1">MPFPLSGDVVAINDFELAFGRYDIFGHNSCCNYIDGKNFGIDARTIVCGQKSTLMLYELCRNKTECRYEAYGSNFSDSDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLZ2</accession>
    <name>A0AAV4WLZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DDB1- and CUL4-associated factor 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DCAF7</name>
        <name evidence="4" type="ORF">CEXT_589971</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016363">
        <property type="protein sequence ID" value="GIY83289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045159">
        <property type="entry name" value="DCAF7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19919">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="112"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY83289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="21496" checksum="D53665EB3E36F85B" modified="2024-11-27" version="1">MTGQVLGRVNLVNGHVKTQLIAHDKEVYDIAFSRAGGGKDMFASVGVDGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQDPNYLATFAMDASEVIILDVRSPCAPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINQIQWACTQPDWIAICYNNCLEILRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WN38</accession>
    <name>A0AAV4WN38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Elongator complex protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ELP1</name>
        <name evidence="3" type="ORF">CEXT_169951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016347">
        <property type="protein sequence ID" value="GIY83164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WN38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELP1 TPR" evidence="1">
        <location>
            <begin position="126"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="2">
        <location>
            <begin position="264"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY83164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="490" mass="55681" checksum="BD5AAADE34D70437" modified="2024-11-27" version="1">MALAGALRVFQLKRPGALPQKLNFLDKPWNNAAQLTDRSMQPDLTLLNQPEMKMCVQQCILLSFKDCVQHNSSTTSVNKINVIHDAFRKVLGTQEMILDIFMLYWLLINAALETYDLKLLCAMVDQNHKRIQKKALNLFPSSSPQRQAIWGEYGNYLMSKRYFDEAGMVFTRCEMHEKALLAYTEGVNWQMALYSANSLSYKGNKIAQLCQDLSAKLKSHQKYLDAAHLLEHYVQDSEEAIVTLVEGCEWNMAMMMISKYNRYDLEESHFIPALKEHHVNLKSHLEQLFKTFSQHSERLKIVRTQKKVKTEESNAITCADDELFSDIGSVTDAASSCAESKQSGSIMTRKSSKNRKKLKLKKYRLKEGSADEDLALIVALSEIATKIDTLKDNFLNTLKAMVHFEFDDAAKTLQELMMKIISVVETEMPIIWNPLENIGSTPDMKFGPDSTVNSITATLQSGNKASPTNIDPELAAPPWRKIELSLQMFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQ65</accession>
    <name>A0AAV4WQ65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vesicular glutamate transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">slc17a8</name>
        <name evidence="6" type="ORF">CEXT_628201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016437">
        <property type="protein sequence ID" value="GIY83854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQ65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY83854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="29373" checksum="C582BA6701ABF87F" modified="2024-11-27" version="1">MIIGMPVSGIFSSMDVLGGWPSSFYLFGACGILWFIFWSTLIYETPKDHPYISAKELECFQEIKAETATVKNRNTLKAIFSSLPVWAVMIAHLGNDYGFTVFMAQMPTYFRDVLHLDILTNGFCQPFRFAGPGLCLLGIIASGCRPELILFLLCLAMFLNGFTFSGYNVTHVDMSPEFSGVLYGLTCTLATVGGIAGPTINGFITATGDSHLNWNVIFYITTAVYFVSGLFYAVFASAENQPWSEVESDINMHIKPDDKYVLKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRD5</accession>
    <name>A0AAV4WRD5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquinone biosynthesis O-methyltransferase, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinol 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.64</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Polyprenyldihydroxybenzoate methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.114</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Coq3</name>
        <name evidence="6" type="ORF">CEXT_258841</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol into ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-methionine = a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="2.1.1.114"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:81215"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:19654"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:231825"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of a multi-subunit COQ enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.64" evidence="5"/>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EC" id="2.1.1.114" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01016468">
        <property type="protein sequence ID" value="GIY84093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061542">
        <property type="term" value="F:3-demethylubiquinol 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010420">
        <property type="term" value="F:polyprenyldihydroxybenzoate methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43464:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="3 5" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY84093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="34943" checksum="58D1B2491BF902F6" modified="2024-11-27" version="1">MSPYSIEIIIFCIRNYSPIFQRNLTDTYSNVQTRERDKRVLTSGFKVHAPEKLDLLSRYTDRKHNLQRWPICSVDAEEVGKFTGRANEWWNGTYSVLQAMNTLRVPLVRDGILYASGITSRKACPLEGFKIIDVGCGGGILSEPLARLGASVTGLDPGLENVEAAIEHASNDDEIKYKVNYVCDTIENFAMISSGQFDAVVCSEVIEHVANVPTFVNSCVELTKEGGSLFFTTINRTSISYVAAILGAEYILNIVPRGTHDWNKFVTPKELSDMLQQLNCRVVSVEGMMYNPLTKTWSWCGSSSNMYALHAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUS2</accession>
    <name>A0AAV4WUS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_465221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016658">
        <property type="protein sequence ID" value="GIY85425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10989" checksum="50DC2539F411A481" modified="2024-11-27" version="1">MAVYVGLESNNWYANSMLWCINRNSRDPGEVPFTTALLKKKNGPWIKEFRDFGEVPFTTTLLKKKNGPWIKEAPIRANDRHEDGKLARPTVRRPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYI7</accession>
    <name>A0AAV4WYI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pol_2871</name>
        <name evidence="1" type="ORF">CEXT_80201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016924">
        <property type="protein sequence ID" value="GIY87338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18389" checksum="0861737AD975B804" modified="2024-11-27" version="1">MCASVIASFMMSAKRIIGCDRDTVKALADFEASLDSTIIDIEDVPSAFSSPSTVIDIEDVRDGYSLTCPLTTDVRNSIDGMDAERSKFKDWLLRYDVLSSAQKGFTPHDGVLEHNFIMHKKFEDARTRKKDLCLAWLDVTNAFGALSHCAIDDALVAAQVGDIPQSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1J2</accession>
    <name>A0AAV4X1J2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Arf-GAP with dual PH domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ADAP1</name>
        <name evidence="1" type="ORF">CEXT_233951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017074">
        <property type="protein sequence ID" value="GIY88528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1J2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005547">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052589">
        <property type="entry name" value="Arf-GAP_dual-PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46021:SF2">
        <property type="entry name" value="ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46021">
        <property type="entry name" value="ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8263" checksum="0DD04CA148ABBCDC" modified="2024-11-27" version="1">MFKTGPRSSDGYKWRWFTLDDRKLMYLEDPLDPYPKGEVFLGYHADGFAVKKGVPPGMKEQGFGFTLRTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBC8</accession>
    <name>A0AAV4XBC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_211311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017393">
        <property type="protein sequence ID" value="GIY91244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9472" checksum="D7B16602B422399D" modified="2024-11-27" version="1">MKITDSKWHDLFSISQIELLQSPADKSDLPPIELENQTGKQLYKSTLCGRHFNLSRRCHLPCRSTKLRIYVPEIPLKGAYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC50</accession>
    <name>A0AAV4XC50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_541341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017581">
        <property type="protein sequence ID" value="GIY92752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14280" checksum="CFFDBC70CAA518AB" modified="2024-11-27" version="1">MFLSVLGGRIERFAGHVGPSGHVLGTSLLDIQLPSPFCHPFCRRSITQLLIFFPLISLLENLVIDSRRNPFLDILLRSTFRLCLGRNIIVTYSMLSESPINSFNERSLAFLNSSKINDDIKFQLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFF6</accession>
    <name>A0AAV4XFF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_283931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017726">
        <property type="protein sequence ID" value="GIY93966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13148" checksum="FDDCA2B4AC49FD82" modified="2024-11-27" version="1">MNTLNITLLVVELQRPTHSYHRTLSGIQYVWKGENHNRVTQKKKQPFKSKQTMHPRPLKTENASKDIKYFPITYAKRVPKRHYSSIALLMECAFPSINTGEKKAIKRDGPRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJW0</accession>
    <name>A0AAV4XJW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_204251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017847">
        <property type="protein sequence ID" value="GIY94948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8766" checksum="21F88455D25AFA0D" modified="2024-11-27" version="1">MQGGKYGNNSGQWFSIWGGSQFRLSDLDCLGEHFHPSDIYEQSCCLLCGMRKSVKKSSSVILKNTGKRFEEKKTPSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL48</accession>
    <name>A0AAV4XL48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_441501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000519">
        <property type="protein sequence ID" value="GIY95413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="178" mass="20414" checksum="35BB1F16D9B62733" modified="2024-11-27" version="1">MIPENMIDNDVMSHDTRMYVMNSNDSFANLTQSKSSLKEGLQQPQSWLTFFTSVIWNDLLVLAGNTIAEPNYQSNRSPKIFRDSPKKSAAFIFSLVNQHWAENKENAYLPRLDLRRIRSFRPVNLDGGQNRQGKKKKKRFVQVVPTMVRFHVQLTVQSSGSFCHANATLDSLLDTLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLJ5</accession>
    <name>A0AAV4XLJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Apolipoprotein B-100</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">APOB</name>
        <name evidence="17" type="ORF">CEXT_738431</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lipid droplet</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017936">
        <property type="protein sequence ID" value="GIY95563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034362">
        <property type="term" value="C:low-density lipoprotein particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034361">
        <property type="term" value="C:very-low-density lipoprotein particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008201">
        <property type="term" value="F:heparin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.20">
        <property type="entry name" value="Vitellinogen, superhelical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052418">
        <property type="entry name" value="Apolipoprotein_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015819">
        <property type="entry name" value="Lipid_transp_b-sht_shell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011030">
        <property type="entry name" value="Lipovitellin_superhlx_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015255">
        <property type="entry name" value="Vitellinogen_open_b-sht"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001747">
        <property type="entry name" value="Vitellogenin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13769">
        <property type="entry name" value="APOLIPOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13769:SF1">
        <property type="entry name" value="APOLIPOPROTEIN B-100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01347">
        <property type="entry name" value="Vitellogenin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01169">
        <property type="entry name" value="DUF1943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56968">
        <property type="entry name" value="Lipovitellin-phosvitin complex, beta-sheet shell regions"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48431">
        <property type="entry name" value="Lipovitellin-phosvitin complex, superhelical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0358">Heparin-binding</keyword>
    <keyword evidence="10" id="KW-0427">LDL</keyword>
    <keyword evidence="9" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="15" id="KW-0850">VLDL</keyword>
    <feature type="domain" description="Vitellinogen open beta-sheet" evidence="16">
        <location>
            <begin position="327"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY95563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="959" mass="110967" checksum="75845B361A1687C1" modified="2024-11-27" version="1">MDEIKLSTITQFTNFVAWIRSAKDLSSFLEEVKSCSYLTEACTPHMKDLGMSYLKDALIQCNSLPCIQAVSHLVESKDISGEYLNYFSWSNMHFSKPEILKFIMNICHATDSDVCWASLGSLFRRIYLSNQKLTEDSKIMHDVAKYFHDNIGRLCMSNDSNSETYPLLLRYLKTVRNMGRSYLLLIPQGIWRLTECVLKSDVPEYVRTFALETLQAVNPCHYEGHCETIYYQRMHILRNASELTTLRSLAYEHIIQIPQKYGFEDDILEILKTDENLQLKSYIANSLKSLLKDSYFMKKEEKDNELSLNKIIHYPGAKSASHVNSQYFSLSFLPDGLKEFGFKTINSNIYESSDVLPRYFNKEFTIKAFSKFIDVFQLGGYSEGLEKVAIVFQKLVKDFNSDIPSFKKILNALQEALKEFKPTQEDSSQEYNFHESIIENIRKLEQIYRKFKPNPESFFTVFSDLFGTTAGYFSAKETIPLSSSTDYDGITLKLDFKRDPCFSLRSGFNLKWDASGVKSGGFCHPSAALTFLNRMVIDFPTITQIGVQANSSGYTSTQWKANLEYSKDKKIFSFVKPTKTQKVLELFRTNQLIKHDRYQDIEDWDLERSSSSSCTNDQWSSALGLQACLSKSYPNVTRRLKPWALLSGWCKWQFFINSFDEKLESYDLEKIESTEAKSKDLIIKFSTSGSEDKREIFLKFEADDTKGERKALVEMPAFPDFIISYLQKKPLENSKERKRYTEVLILKLRKDQEYQLIYNEEDRLDNRLGNVAADESPTDKKPAALVHEQVLSLDTPYNSYRLSKEDSKNAEDTKMKVFFSYDNRNPSKKWLDTILPPSFWETEGKAWLLFQINWKEPKVFTDTTTRQTVCFVKDPHALIYLDANSFETAGSEQININLTKTEINTGKLLGFANFTYDFWMSRNDEHKETRDFNLTVGPKSWTVQMQNVMVGTNLPSKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMN2</accession>
    <name>A0AAV4XMN2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial 2-oxoglutarate/malate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SLC25A11</name>
        <name evidence="10" type="ORF">CEXT_206101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017981">
        <property type="protein sequence ID" value="GIY95934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="99"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY95934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22835" checksum="73C615878F53B588" modified="2024-11-27" version="1">MHNLADNRLLASKIIICFEESINWVSKRQQMNMAVARGGKKRLQKCFDALIRITREEGLLTLWRGCLPTVGRAMVVNAAQLASYSQAKQLLMSTGYFKDNIMCHFASSMISGLITTAASMPVDIAKTRIQNMKIINGVPEYRGAGDVLLKVIRNEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNQSYRIYVLKDKSGGGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP04</accession>
    <name>A0AAV4XP04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_86361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018083">
        <property type="protein sequence ID" value="GIY96731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17507" checksum="29A94E6DA558F4AD" modified="2024-11-27" version="1">MRKLGGDCITIDSQSGSRSIGPFLASDVSCSHCFEKLSGDCDSVDSLSAFLKLLITIRKLNKGSAPNLQREREKKSTSSSERWGVSEKEEAPTRDPKWRKAGKEPSPLSCSVSRRRHGSFLRKCHCSQRGCLQIAGKNEYFLNKMRGNEVIGLHADCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUP6</accession>
    <name>A0AAV4XUP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_20781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000915">
        <property type="protein sequence ID" value="GIY98323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46596">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, dispensable insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I catalytic core eukaryotic-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase I C-terminal" evidence="4">
        <location>
            <begin position="83"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="36"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="1">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY98323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14529" checksum="0E9AAC5C8AFAA196" modified="2024-11-27" version="1" fragment="single">LHECSSKVSAYKPAKTDVAVLCNHQRTVSESFIRSMDILQSKMNALVLQIRELDKEVKAAKKKRRIQVPEQRKKQQQLAQLQQQLKELKLQAADKQEIKLITQETSELNYLDPRISVAWCVFFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XV49</accession>
    <name>A0AAV4XV49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_97681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018254">
        <property type="protein sequence ID" value="GIY98075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XV49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="14173" checksum="8E59FAF6D5ED7EAE" modified="2024-11-27" version="1">MIKSYQVRKKPLLLKISFPFLSPFPFFMSRNSPDLFPRCSFAKMDAQLRQSELKTLELLTPHLRLKKKNHLHQFSVVFSLSWIEASFSFQKDILLEKYCCRATLKHAGILPTAHSLFLKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWB6</accession>
    <name>A0AAV4XWB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">G_PROTEIN_RECEP_F1_2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVEN_155711_1</name>
        <name evidence="9" type="ORF">CEXT_725831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018274">
        <property type="protein sequence ID" value="GIY98264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22750">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="216"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY98264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="395" mass="44816" checksum="A2157160D6AF66AE" modified="2024-11-27" version="1">MRELLLDQHRMRHAASRFALRDYHEHSHPHHDCWKLQQCKDFLLNNATLQLNIQVLATEESDKDSSGDNVSSTLPPVVSVLSEEENEVKILYQTVVPVMLTACFLSMIFNLVIVFSVRWVRRLSPTLYLSLSLSVADAYASLVIGIGLVINSLLPTVYGMNLGLFNNCYILVLEAFSDCHKTDCCLCNYRYVGGSCTLFLMYFSLVPNDGFQSQYCSRVDFLLHVPFRVTTSVLFFVPLILMSGMYTHMFILVQKHQRGLLQSPSSRQLHKNVKATITTLLILGTYILGWMPAVLYFVLTCLDCPVPYPEIPLWVRIPTGIFINSMIVLKSFVDPIIYVVRMPEIKTAMGAIWRTRCGIHTPLTTDIPLNSRSDIHRVTFNVISRRAKVNGVSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWH2</accession>
    <name>A0AAV4XWH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_60031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018425">
        <property type="protein sequence ID" value="GIY99505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10094" checksum="14657B04F4906A5D" modified="2024-11-27" version="1">MVVKLKVLFKEAETKTKGLKDADELEMWMNPPGFECDSQLVTELSYPRKLNHLPAWQRCNCLSSTVPKAMSVFNTCLNKSLQRRKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0E5</accession>
    <name>A0AAV4Y0E5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_360491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018481">
        <property type="protein sequence ID" value="GIY99998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="12311" checksum="BC5F2CA367EE1083" modified="2024-11-27" version="1">MKMKMSQFHSQFEEHFHFSHVEPYSDQRYTSLQVSREKKCSLDKQAYLAHLWWFPAKQRVSNRRGRIHLNLSIDRREHGIEYNKKREENNNSDVVKRLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1S6</accession>
    <name>A0AAV4Y1S6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNase H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_166593_1</name>
        <name evidence="2" type="ORF">CEXT_665741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018502">
        <property type="protein sequence ID" value="GIZ00100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1S6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="114"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20346" checksum="403A84635AE394E0" modified="2024-11-27" version="1">MRSISFLQPWSAHATMQANQRPRILPTAKSAPLRQNDTHFGKIVFLYLYPLGLIWKQGLADIEVEPSVPFNLLTPTTVLSNVTFNEDLKVNFIIHEEHPKLLRQLALEIINNISPRDLVIYTDGSKSVSGRTGKGIFMKTSTGEFRYRFRNPDHSSVFRSELIAISEALSLALDLKVPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y255</accession>
    <name>A0AAV4Y255_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_433991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018521">
        <property type="protein sequence ID" value="GIZ00235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y255"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16243" checksum="7E4AAC9987376210" modified="2024-11-27" version="1">MSLVKPSTLHISVRMVNPSGVHFYKTNGKHSGQWKYHLQYEKRKLSVRYCFSRTEKSLVRLQIIPLGLLGCQFANNCGSSPNLRSSEAFSLTLGMMNVVCLRYVLIHLKRKSHHTGNRASIIRVTSLVRSGLHLLTDILISHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3I8</accession>
    <name>A0AAV4Y3I8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_496931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018736">
        <property type="protein sequence ID" value="GIZ01903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9961" checksum="CD06942E23B96EA9" modified="2024-11-27" version="1">MKVKSDSAVPIAAAVKKKRTHRQPGIKADMKVLGRGYLVISSQGKSMTSLTYFISYMPTFTSSHTKLTRSPGESVSSSQMMQDVFGETVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5N6</accession>
    <name>A0AAV4Y5N6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DDX52</name>
        <name evidence="9" type="ORF">CEXT_214151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01001437">
        <property type="protein sequence ID" value="GIZ02325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="52"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIZ02325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="28327" checksum="8E9B635AFB3598D2" modified="2024-11-27" version="1">MFSATFKQEVEEWCKLNLDSLVCVSIGTKNTAVESVQQELRYTGCESGKLLEIKNFFCKQMKGIQPQCLVFVQSKERAKELYSELIYLFTKVDVIHADLTQEERDKVMKNFTDGSVSTLICTELMGRGMDFKGVKVVINYDFPTTAIEYIHRIGRTGRAGEKGRAITYFTSDDVKNLKDWHDALGLLFTRLHNESQNCKGKKMKNARPIKREKISTVPKYDLEKQYKKKKLIQNSIKRKKKQSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4Q6</accession>
    <name>A0AAV4M4Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dscam2_90</name>
        <name evidence="3" type="ORF">CEXT_302211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019393">
        <property type="protein sequence ID" value="GIX67359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX67359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="228" mass="25670" checksum="0943F0385F15EDE2" modified="2024-11-27" version="1">MDYRYIAGYHRILKMIDSCYSMGPFDRSEEVITAMRDFILSYGRPLPHNHRQKTFPNGTLVIEDLQRSRDGGQYHCVAENNRSRTARRDLLLLLNPFRSRPRYRKASGPPSLASCPQGSSHPHLLDEGWPTLPDDLWGSISTVNEFTSTLSFSSVSQIHNGNYTCIASNPVASRNHTATMIVKVPPKWRTEPSDKSVVMGQPVMFDCQANGYPIPLYAGKKSSGIPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4W6</accession>
    <name>A0AAV4M4W6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2</name>
        <name evidence="2" type="ORF">CEXT_76551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001873">
        <property type="protein sequence ID" value="GIX67393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4W6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="56"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17045" checksum="7E727E74CB4A3469" modified="2024-11-27" version="1">MSIKLAEYLLPKILVGPNASSKNELRNFLKCLLMVGIKAPRQICTGCCHFLNTVLPPFTIEPPNKVIFLNSSGESVHCAALGNPRPSISWVLADGTAVTDLPGLRLSLANGTLLFLPFMAESYRQDIHASTYRCIASNLVGKISSRDIRVRAEYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAG8</accession>
    <name>A0AAV4MAG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_273151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002006">
        <property type="protein sequence ID" value="GIX68870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8318" checksum="D5C75FCF04CAF52A" modified="2024-11-27" version="1">MKRIVACPLMIDNPLLYVPLPHRFNPNGQSMAGAGPHRSSEKGDEPTSSHPNSQRSRADLSSPDPLESARHPLPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MB84</accession>
    <name>A0AAV4MB84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_143171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002019">
        <property type="protein sequence ID" value="GIX69138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MB84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15294" checksum="D4ED6277B8F92D54" modified="2024-11-27" version="1">MFWRNYNDGYCTARTHIGVKKKIWFIRNFSTLEKGNELTYRIKSTLNDKSMVTLKFSVTGDDETLQVSFISSDSKDYLRSTFSIKISVLESNGDAATCGEAKVLFVKEPLKKESKMFINKKRSNEKENSVSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MM87</accession>
    <name>A0AAV4MM87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_316101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019911">
        <property type="protein sequence ID" value="GIX73084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MM87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15196" checksum="62857174AD2C6A49" modified="2024-11-27" version="1">MEPKLTSRTRRTTPRSSPRKDPVTLREQRAVPAGDIQIRYNTSHHLFSIQNKHPIPLHCFNGGSKISNILHLLQFGGQLNYESMLINGNMEPKLISRTRRTTARSSPRRDPVILREAESCSAGYVFPEMKDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN58</accession>
    <name>A0AAV4MN58_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_475141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019986">
        <property type="protein sequence ID" value="GIX73779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="19425" checksum="468574D56CF0FCF0" modified="2024-11-27" version="1">MILPSSHTFYCHFEIDSGEHIPLRNMHCEGKTNESKHQKFIHLSYLQAPPSIRTFFSGHSLRTRACISVVRGPRDEISSSGDRMERTGHQQTTTTTEWPAVNWVYCGQRRNHHLKRENWIPCWSLGFKDERSFLTECPWAECLDVCPFSNKKSILNIHDGLLLWGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRS7</accession>
    <name>A0AAV4MRS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_235613_1</name>
        <name evidence="3" type="ORF">CEXT_23821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020128">
        <property type="protein sequence ID" value="GIX75058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF76">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX75058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13633" checksum="7020EABF88422D20" modified="2024-11-27" version="1">MGLRDIYPLYQPIGFHMVASSFIPFPVVYGALVDSACLVFEERCGETGNCWIYDNSKLGYLLHGASAMFTVLAAISQLGVHLLSGRVGNLYEEDDEVEDSAAENKKKEAAEDQRIRQESLTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTI4</accession>
    <name>A0AAV4MTI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_322751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020151">
        <property type="protein sequence ID" value="GIX75240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13149" checksum="682B020DB9F54D85" modified="2024-11-27" version="1">MAQKRSSILQRTSRCLNLYSPSQKVACRSSCLRPLSSPTCNGSILFETYESMQSYFPNFPTCYKKKVYEACLKLFSSIMRFCARMLGNSSHWEFGSFDSELDFQSVKEDLEIHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVF0</accession>
    <name>A0AAV4MVF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_346541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020107">
        <property type="protein sequence ID" value="GIX74879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="28" mass="3107" checksum="F390100CE5473F6D" modified="2024-11-27" version="1" fragment="single">MLQSRTPFGKRFPGMFIWGLAQPGGTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX00</accession>
    <name>A0AAV4MX00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Condensin-2 complex subunit D3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NCAPD3_2</name>
        <name evidence="2" type="ORF">CEXT_58171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002590">
        <property type="protein sequence ID" value="GIX75479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="260" mass="29709" checksum="DCCF87F3DA44DD85" modified="2024-11-27" version="1">MAYTLPVNHAKLFCSICDVLTCIAEVFPINKRTESIARDCMAILNSLEIRAYDSHNVISELEEPEEYINAEREIRKVTLVEPIIPIMISLKNRMFKESNALMLEIFIFIKDLLVDFESEIDKILAGDKMLKNQVMFELKNEEKEVPKQQKKHEKQRKTSTSPKADIFDQVYEVSATIFHGVRNSFSPSKETASEQIQIPSPAINNDLQLPSTSGLQNMDVQRELFSSSLNPVIPLKRLKLKSPNISKINLTMEDFDSNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MY59</accession>
    <name>A0AAV4MY59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_641021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002655">
        <property type="protein sequence ID" value="GIX76257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MY59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12792" checksum="240A4DC1BD3AF398" modified="2024-11-27" version="1">MPDESVRHVYVNKIRWYYPQLKVVTKHGESGLVLFHFALPEISVVSFDKRASRCDSGGFRGRGLEAQKRAASLSDTGSDSAVVKLSGPDKQTKTICSASEWNGSTSSAPDRTDSDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ND42</accession>
    <name>A0AAV4ND42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_66431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020790">
        <property type="protein sequence ID" value="GIX82558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ND42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="305" mass="35268" checksum="97B51A2F43F03018" modified="2024-11-27" version="1">MSPYFLLPYVSYIPPIQPYYITPILFLLSSYSYIPPIHPYYITPISLLPPTPISPIFLLSILIILPYSLLPPTPISPTYILLLSILIIVLPILFFLLLLYLLYSSYPSLLYYSYSLLPPTPISPIFLLSILIILLLFLLPPTIFLLSIIIILLLFSSFPPAPIFPPIHHYYITLSISSSSCSYIPPIHPYYITPILFFLYSYISPIHPYYITPILFFLLLLYLLYSSYPTLLYYSYSLSSSYSYIPPIQPYYITPILFFLLPIFLLSILIILLLFSSSSYSYIPPIHPYYITPILFFPPTPIFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGE5</accession>
    <name>A0AAV4NGE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_54681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003272">
        <property type="protein sequence ID" value="GIX82923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="328" mass="38170" checksum="D0B408401DD85A44" modified="2024-11-27" version="1">MVITTNNRFFRRQTFLPGYQSAENVFISKSISISDPSAHPFIHSSLSHLADRERNLGFRFHSNRMPRLVCVKNHSRGVRPSDCRGQGIGSPRPIIQEILSFQKMIFNEVGTFLECSFSFVLEKAKISVQPTRGQTFLPDCQIAENVFISKSISISIRVLIPHQHSSSSLAPNPFEDNQYLLPRHFSLPRNSHMAREQIRRRVKVERERGKERQRTRNLRFRFYSNKMRAKISVQPTRGQTFLPGCRIAENVFISKSISIFECSSFHQFLLSHLILLKTIRSAPWTLFLKFPYGTRANSREGEDKARDREREIWNFDFIRIKCQDSCVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NH00</accession>
    <name>A0AAV4NH00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_97181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003263">
        <property type="protein sequence ID" value="GIX82724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NH00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8641" checksum="CFE9C811CC4F041A" modified="2024-11-27" version="1">MPDLRKENSETFEGNALYPIFGYSGKINSELSETNFPNESSECLTESDEEGPKRIKRSTSRFYFKTFCEAEKESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKN6</accession>
    <name>A0AAV4NKN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase subunit gamma-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">polg</name>
        <name evidence="2" type="ORF">CEXT_799021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020948">
        <property type="protein sequence ID" value="GIX84290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005760">
        <property type="term" value="C:gamma DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002297">
        <property type="entry name" value="DNA-dir_DNA_pol_A_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041336">
        <property type="entry name" value="DNApol_Exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267:SF0">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18136">
        <property type="entry name" value="DNApol_Exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00867">
        <property type="entry name" value="DNAPOLG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mitochondrial polymerase exonuclease" evidence="1">
        <location>
            <begin position="45"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="448" mass="51917" checksum="72A323AA256A7B20" modified="2024-11-27" version="1">MLSKSLHRQIFGQKPDLIQDNKDLEDIISHLKKHNLWQAKTSTLPDVDFQLPQLHNSDIIEHFYHIASEQIKDYKELLLDLSNCELPPIPQNWKFQSGWVQYDKSGTSRSVDFPEESALVFDVEVCMREGNFPTIATAVSKQHWYLWCSERLTEDHFNWSKNVSLSELIPLETTKSEIQLPKHKKWKPKIIVGHNVAFDRAFQTKTTFLDTMSLHMCVSGLTGMQRAMSLASKKKKNENGFLNPAIGWSYISSLNNLGDVYNLYCKGEIKKAEREIFVTGTLSDIKEKFQELSAYCAQDTWATFHVLKKIMPLFLERFPHPVTLCGLLELTSVYLPVNQNWERYIHEGQSTYEDLQKELKLSLVHLANDACSLLPNKLYKADPWLWDLDWSVQNIKFKKAAVTTVKTKQNKSPKENIEINSKNGDIVENLDSKNEEERKQYQTILIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NL11</accession>
    <name>A0AAV4NL11_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Solute carrier family 23 member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Slc23a1</name>
        <name evidence="7" type="ORF">CEXT_789231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021025">
        <property type="protein sequence ID" value="GIX85054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NL11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11119">
        <property type="entry name" value="XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX85054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34059" checksum="3381DFB76043B340" modified="2024-11-27" version="1">MGNPARTDTLLPVLENSPWFRVPYPGQWGLPTFTMASILGVLAGSVASAIESVGDYYACARLSGADSPPKHAINRGICVEGIGCVIAGLFGTASGVTSFSENIGAIGITKVASRRVIQYGSLLMILFGMLGKFGGIFVTIPQPILGGMFCVMFSMVTAVGLSTLHFVDLNSSRNIFVLGFSLFMGLCIPKWIQANPGAIQTGNEIADQIITILLSTNMLVGGFIGFLLDNSIPGTDEERGILKWRKQTNIDSGRSVSSKTYELPFITNFMKKHPFFRFLPTSPSYEEGSMKNKFFIVRNYFKREKSTEISRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR38</accession>
    <name>A0AAV4NR38_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GDI2</name>
        <name evidence="4" type="ORF">CEXT_725271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003573">
        <property type="protein sequence ID" value="GIX86240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.519.10:FF:000005">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000158">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX86240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="410" mass="46671" checksum="2AB87BB635FD0B45" modified="2024-11-27" version="1">MDEEYDAIVLGTGLKECILSGMLSVSGKKVLHMDRNKYYGGESASITPLEELFAKFNMPATQLEEYGRSRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSVEGSYVYKAGKIYKVPADEKEALGSNLMGMFEKRRFRNFLVYVQEFNLNDAKTWKDVDANVTTTAQLYEKFGLDKDTADFTGHALALYRDDDYLAKPCLETINRIKLYSDSLARYGKSPYLYPLYGLGELPQDLQDLVQFMQVYCDPSYVSDKVEKVGQVVRCICLLNHPIPNTKDALSCQIIIPQKQVGRKSDIYVSLVSYTHQVAAKGWFIAMVSTTVETENPEQEIKLGLDLLGPIKQKFVWVSDVFKPKDYGEESQIFISQSYDATSHFETTCLDVLDIFRRGTGEDFDFSKVKHDLGDEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR88</accession>
    <name>A0AAV4NR88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_269751_1</name>
        <name evidence="2" type="ORF">CEXT_357551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003683">
        <property type="protein sequence ID" value="GIX87490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048011">
        <property type="term" value="P:neurotrophin TRK receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026682">
        <property type="entry name" value="AKT1S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21844">
        <property type="entry name" value="AKT1 SUBSTRATE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21844:SF2">
        <property type="entry name" value="PROLINE-RICH AKT1 SUBSTRATE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="457" mass="51769" checksum="06FD8976C36F3B64" modified="2024-11-27" version="1">MHIQVGNVSLFPMPGLAPCSEKMISLEAHVCEHHNYLSDLRIHQIGIMILLVCSCLNVRVHGRGNTFNLRDSDSLDVPENVLRDPFFESQVYPVTMDLAGVTMVSLLFSKVLCKVRCIENWTITTCACCTMDVFAKRVDNNDEVLVSYKVQTNANYISSLMDSDKYSPLFKMILPEVNDNFCRNNIGIEYQNGKVDNSLKHVQVLVSNYLKAEQKAMEDRIRQFTEQQQSSYSNLLEKVRKNKQAMIYLMMKTKESQTEGEVVPESSIGSPSVLNRDSANDSSTSTDSAFDRSDTTDLPIDVVKQQKNRVLRRTVSNPARSRTKRRMPKRTSSIDVGGMFDMEGFDTQELSDEYIDESEDEASTNVEEDKHDSMCATSLPMSIPVFTNYPHYSLLEDDEDDKEPYPKAPEDIAASMRAPSLQFILYLFTLFPGAGMSCSCKLHKCNMTFLSVDFKIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NX54</accession>
    <name>A0AAV4NX54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_647711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021310">
        <property type="protein sequence ID" value="GIX88325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NX54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8643" checksum="8F949376719E6BED" modified="2024-11-27" version="1">MGGKLLEMKKQLALTSPSSIDGHVKCQRPVTEEHRLLFVPSNISQVSGCSKVTVQNRMMETGKCFGNFCWPEIESASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NY99</accession>
    <name>A0AAV4NY99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_503191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003887">
        <property type="protein sequence ID" value="GIX89784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NY99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12135" checksum="B9DE14E1B89021F9" modified="2024-11-27" version="1">MSYMWYPSIITTAPDTHLRKAAPGNGFRGAKLKADSRVRQSQRRRIASWPQAAMAGEGTSPAFTPQQMPVCLVADHACQLLQEPRRVRSGVDASDSRHFRVVRDHCSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2D2</accession>
    <name>A0AAV4P2D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_594701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021580">
        <property type="protein sequence ID" value="GIX91402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7746" checksum="FB1D3E5A467A93BE" modified="2024-11-27" version="1">MRGTTEDSSIYQEGSWQLDEEKKGLEGEGPQTHPPPPLHLQKHFSTLELEPGRENAIVIQWPFFFVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P458</accession>
    <name>A0AAV4P458_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_308981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004082">
        <property type="protein sequence ID" value="GIX91975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P458"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8109" checksum="9DEAFA6128D4D695" modified="2024-11-27" version="1">MRGNGSSIPSRSRDIVSESGKVPLMQFHTRHVGDEFRIILDAHTPAVDVCLVLGVLFITSLTLEVLESFLIGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA33</accession>
    <name>A0AAV4PA33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_772671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004312">
        <property type="protein sequence ID" value="GIX93924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8856" checksum="3BB2585C9789A471" modified="2024-11-27" version="1">MFPQNIRVFSCISWPLLDVPNNQLPSTYQAHTVLNISFDAWSDRHSRLPWLLESPNELVATLFTARSVNHSTFAGIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAZ2</accession>
    <name>A0AAV4PAZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_582461</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004168">
        <property type="protein sequence ID" value="GIX92861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060076">
        <property type="term" value="C:excitatory synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030672">
        <property type="term" value="C:synaptic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005326">
        <property type="term" value="F:neurotransmitter transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098700">
        <property type="term" value="P:neurotransmitter loading into synaptic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050803">
        <property type="term" value="P:regulation of synapse structure or activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035249">
        <property type="term" value="P:synaptic transmission, glutamatergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF456">
        <property type="entry name" value="VESICULAR GLUTAMATE TRANSPORTER, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX92861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16369" checksum="E9D139D53528A541" modified="2024-11-27" version="1">MLRFKTLLRLFSGFNVNHLDIAPRYASILMGISNGFGTLSGMICPIVVEELTESEKQAWAEPPPEDEGPSWNPLENAFGDVKQNGGTPLCRGYNCSDRKSTTTFIRIHRYGLQLPAAAGLRDPTRNGTATINGPLHAWYHRRKGVLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PH86</accession>
    <name>A0AAV4PH86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_669791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004498">
        <property type="protein sequence ID" value="GIX95345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PH86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13376" checksum="4DAC4CE4EC4FC79D" modified="2024-11-27" version="1">MRIDPTCSKSYDDRLIACTESYDNRPTTYSMITIKMSPNYVMPIIVMPIIFTNLCVVLSLWDPRCLEGHSTPNQSEFEMSRQNDIINDARRTIHLHVRKEEKEKTMGMLRYLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHV5</accession>
    <name>A0AAV4PHV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_635901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004493">
        <property type="protein sequence ID" value="GIX95321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="207" mass="22792" checksum="AC6EB6C45D4EF164" modified="2024-11-27" version="1">MLAICWLNKAADFHKHRKIANGKVLEVDEASRKTALVSCPVWKSKGGQATGASLDALSDTNAEPPAAAGGGVGGGLPAAGPQHRPRHLLHQEEEEQELQLQRKPQGPHPDHHPRFVDVHPQQVPAVHQRRGHLPGGRQRQLPRGDTHERALRECHFFFHSLCSASSVAQTNQGPSSTKRTLHATASLRWLSRVMFGNIQFERGIRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSV4</accession>
    <name>A0AAV4PSV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_471841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005128">
        <property type="protein sequence ID" value="GIY00016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="14511" checksum="ACC9DE96593F84D6" modified="2024-11-27" version="1">MYFTIRNRINFVKELHATLNEHEKNHLSCLHEQLINAFVARRLKREFKKESKNSAMFEPHFIHADYKPDRIMAIKKQQTRGVIPFLDIERRSRISRNRYVVYSDPFDANFLFLQNRFHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q108</accession>
    <name>A0AAV4Q108_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_698541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005422">
        <property type="protein sequence ID" value="GIY02211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q108"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12296" checksum="5986B606259FA465" modified="2024-11-27" version="1">MHIYFTSLCLADESHIRPFVHWSDGFFNPLSTLVHYVNLPGWNCKKERRKKNISIQPIFYIHSSTSTNRSRRHAQLQQKKWVLNLLECWTRLEQFANGNAISGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2D1</accession>
    <name>A0AAV4Q2D1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_375231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005584">
        <property type="protein sequence ID" value="GIY03484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2D1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="63" mass="7603" checksum="B5CA181A34B42BA9" modified="2024-11-27" version="1" fragment="single">ALFTEDQRDSPSELAFKYSIYRINKRQDSTRQHDTCVRHTTRPERRQFPRSQKKGRAPRQLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBN8</accession>
    <name>A0AAV4QBN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_47771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005970">
        <property type="protein sequence ID" value="GIY06520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043966207" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="6004" checksum="9991F1E925A3B4DC" modified="2024-11-27" version="1" fragment="single">MFFSKIVTALTLLALLSFATADDPKDCEFQNNLDDLINMILSLVTGLIDLITSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCH7</accession>
    <name>A0AAV4QCH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tubulin polymerization-promoting protein family member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Tppp2</name>
        <name evidence="3" type="ORF">CEXT_693271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPPP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005984">
        <property type="protein sequence ID" value="GIY06646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001578">
        <property type="term" value="P:microtubule bundle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032273">
        <property type="term" value="P:positive regulation of protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932">
        <property type="entry name" value="P25 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932:SF9">
        <property type="entry name" value="TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY06646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20344" checksum="AC00B1324C858D7D" modified="2024-11-27" version="1">MSKENEQKGEAKDLAALFDKFAKFGDRESDGTITLKNIDKWMKQADILDKKGGVTHADTAITFSKIVKNKKRMNLKEFQQFIETLATDKKIEPKEILDPLIATGEPKMGGVTTPITGGAVGRNLRRMTDTKLYTGAHKERFDEEGKGKGKGGREEITDDSGYVRGFKKDEKKKEDEEKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGA5</accession>
    <name>A0AAV4QGA5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="6">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="primary">CILK1</name>
        <name evidence="25" type="ORF">CEXT_813021</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20 27">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 27">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="6"/>
    <dbReference type="EMBL" id="BPLR01006232">
        <property type="protein sequence ID" value="GIY08332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07830">
        <property type="entry name" value="STKc_MAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000104">
        <property type="entry name" value="serine/threonine-protein kinase MAK isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000071">
        <property type="entry name" value="serine/threonine-protein kinase MAK isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 21 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="18" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 21 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 22" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="24">
        <location>
            <begin position="8"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="GIY08332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="457" mass="52963" checksum="A5AAB6D77AB2462C" modified="2024-11-27" version="1">MGIMSKRYKFMETLGNGTYGTVLLAHNLDSGEKVAIKRMKKKYHSWEECMSLREVKSLQKLSHANLVKLKEVIREDNTLYFVFEYMKENLYQLIKSRDDAFPENVIKNILFQILQGLAFMHKHGFFHRDIKPENLLCMGPDLIKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRATNYNSPIDMWAVGCIMAELYNLKPLFPGRTEIDQIFRICSILGTPDQRDWPEGHRLAAEMNFKFPQFVETPIQSLVRNASQDGCILLKDLIRWNPDKRPTAVMAARYPYFKNGMKPMAQTNRRVSAFNRHLPDSYQENIPKIKASEEKSAYRKRWGDHLSQENDIPTSDSDSNLDRKKVVERQSSQDMIARFSGKQQYAAKPRYMSGTNSRNVLYNDSARLKMNGHFNSNAFPVSFDRRNSQPTINGTPVQKSARAYGQHSNPVFSIPGKIDWSAKYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QLN1</accession>
    <name>A0AAV4QLN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_140991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006352">
        <property type="protein sequence ID" value="GIY09276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QLN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11257" checksum="F16F226F06700D84" modified="2024-11-27" version="1">MINPLTLFKAYFNRQPVSDLADINCSFPDEWANISLEKKRAKNAENEEDIRFESPVDKRERGGHLVRLRRFFFYSYSAFFLSLLHTRLFRIHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQ07</accession>
    <name>A0AAV4QQ07_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Sodium/potassium-transporting ATPase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">Atpalpha</name>
        <name evidence="20" type="ORF">CEXT_56921</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Cell membrane</location>
            <topology evidence="1 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006641">
        <property type="protein sequence ID" value="GIY11389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQ07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000144">
        <property type="entry name" value="copper-transporting ATPase 1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000106">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000001">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005775">
        <property type="entry name" value="P-type_ATPase_IIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01106">
        <property type="entry name" value="ATPase-IIC_X-K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF13">
        <property type="entry name" value="SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0187">Copper transport</keyword>
    <keyword evidence="14 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0630">Potassium</keyword>
    <keyword evidence="17" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="16" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4" id="KW-0740">Sodium/potassium transport</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 17" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="50"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="GIY11389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="549" mass="59843" checksum="A3AA00BEC7B18C0B" modified="2024-11-27" version="1" fragment="single">MIQGSSTLKFTSLAELYLGIVLSVVVIVTGVFSYYQEAKSSKIMESFKNMVPQYAIVLRDGQKLTMPAEEVVVGDVVEVKGGDRIPADMRVISAQSCKVDNSSLTGESEPQTRTAEHTNDNPLETRNLAFFSTNCVEGTAKGIVVNTGDRTVMGRIANLASGLEVGDTPIAREIEHFIHLITGVAVFLGMAFFIIAFILGYYWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMASKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIIEADTTEDQSDDTKTSFFGVQYDKSSPGWTALSRAACLCSRAEFKPGQDSIHILKRDCTGDASESAILKCMELAVGDVMAYRRKNPKVCEIPFNSTNKYHVTIHETNDQKDPSYLLCMKGAPERILERCSTIFIGGKDKILDEEMKDAFNNAYLELGGLGERVIGFCDLPLPADQYPHGYPFDADEQNFPLDNLRFIGLVAMIDPPRAAVPDAVAKCRSAGIKVIMVTGDHPITAAAIAKSVGIISEGNETVEDIAMRLDIPIEDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R096</accession>
    <name>A0AAV4R096_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_462541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006993">
        <property type="protein sequence ID" value="GIY13736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R096"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9878" checksum="7BBD1802AE489E00" modified="2024-11-27" version="1">MRLLLVSIIFKNDTVSSIKHHLLASSIFKNDTVSSIICWFQYHDTVSSIKQHLLVSSIFKNDTVSSIKQHLLVSSIFKNDSFKHPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1Y8</accession>
    <name>A0AAV4R1Y8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_356041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007053">
        <property type="protein sequence ID" value="GIY14277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1Y8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12245" checksum="29D7C777A0A279E6" modified="2024-11-27" version="1">MRMGMIKLPATIGFILGGYGGGVDEVSNATDITLWEIRSKYGGLEVNILPLRQYEFGKGVSQKYDCKEGRIGKYECASFVSHAGESTGQSNCHESTLFSIYLEFKAVNVAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R525</accession>
    <name>A0AAV4R525_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Constitutive coactivator of peroxisome proliferator-activated receptor gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAM120B_0</name>
        <name evidence="3" type="ORF">CEXT_782941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the constitutive coactivator of PPAR-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007273">
        <property type="protein sequence ID" value="GIY15711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R525"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026784">
        <property type="entry name" value="Coact_PPARg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15976">
        <property type="entry name" value="CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15976:SF17">
        <property type="entry name" value="CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY15711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="19568" checksum="7A6BCCBE823C4511" modified="2024-11-27" version="1">MGVRGLQTFIEKDCSEACKYVSIKQLADKHRHVFNCQPAIVVDGMSMMNRLYTNTSLEWIYGGQWLQFFDELKNFIQCFKNIGVKLIFFFDGTVCALKRDEWVRRRLSKAETVVNIFKIIRKSKTQPDKALFQLPTSMGLLARFAIKELGADVYQTDRDADDVIAEYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5K7</accession>
    <name>A0AAV4R5K7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_30691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007441">
        <property type="protein sequence ID" value="GIY16924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11275" checksum="60AEA3ABC940576D" modified="2024-11-27" version="1">MSTEQWAGATVVLQALCISIGNWRIVKNFWLYFSRKMRYCIMLSPHSSKYGPIKKSFTKPAPYFNKKNRPEKACGRVASGLVVIYIWELCKLKTPLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R960</accession>
    <name>A0AAV4R960_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_551811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007468">
        <property type="protein sequence ID" value="GIY17139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R960"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8092" checksum="7D8529CAA94CE6AF" modified="2024-11-27" version="1">MPDVHKRFRSGSLLMRDGYCKLIPYCLIFATTSTQRYDRRDVTNLHDNAPGWSSKCHVVSARLGSRPFVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RF82</accession>
    <name>A0AAV4RF82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007953">
        <property type="protein sequence ID" value="GIY20978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RF82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22798" checksum="170B08F1546476F5" modified="2024-11-27" version="1">MMRNTFASRPYTVPPRRLRHSTRIWNGPYPQGPPPTLYTHFQTHPTVGYAPTLVNGLFQPQPAYPNNNYSPNGSYIQPTTSLGVFPNYSYFMHPQPSVGYPSNIYSHSIQPQPMHSKSTTSIDCPFLKLPETIQFSKVLDNPEGFRAVTPSNSFDSLGYDVYVPNYLSKDIIYYLEPDDKPSSIRASCWKYHSTCQSIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJI7</accession>
    <name>A0AAV4RJI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">spop_82</name>
        <name evidence="2" type="ORF">CEXT_624031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008036">
        <property type="protein sequence ID" value="GIY21595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11878" checksum="EB76CBE191533F99" modified="2024-11-27" version="1">MYTDTLDDLCWENASQLFSAADKYQITALRNECSVLLKDKLSHANACQILILADTHQDESLKKIVQAYIVSNNKYIFKLEEWKLLMEDAPKLAAETMFQNFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RK79</accession>
    <name>A0AAV4RK79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_24371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008104">
        <property type="protein sequence ID" value="GIY22110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RK79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15043" checksum="2838594558B9EA51" modified="2024-11-27" version="1">MEESCVGLATWTASCDASLGIQSDTPSSRKADEDGHFNDDDEDHFLGIDSEDGHEDEEPLPPLALPLQNDQKGDAGEGAMLLKISSSPPLSSGGRKFAFLPERAHKSLPFLPGAKRKVPLFNFRGAHQFSLMPPRRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKK4</accession>
    <name>A0AAV4RKK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_181610_1</name>
        <name evidence="2" type="ORF">CEXT_719531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008205">
        <property type="protein sequence ID" value="GIY22838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14333" checksum="DACA7EA40FB19842" modified="2024-11-27" version="1">MAQCAWRTSPVFWRRCVWTSQGREQSDAFSTLQQRRSEELSLVLLPQPPEEKLATHKYIGMEDHLQMNEMTHLNLPERDRSRSASPADSLTSSATDISMLPIAGRSSHKRDDYVSTDFPPVSRTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLE2</accession>
    <name>A0AAV4RLE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_267493_1</name>
        <name evidence="1" type="ORF">CEXT_302961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007974">
        <property type="protein sequence ID" value="GIY21161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="18822" checksum="2FBFFFD7705D20A3" modified="2024-11-27" version="1">MTSVGNWPGFNFTPVTESFWDSNYNPSVGSWTDKAEECEVLNSSPNNIWNDALTPIWETSLDTWSTPNCDKSNSITESVLDENILINSEKINDENKECAVGKFNPFHTPSAQWISELKETKEVFNGSSESNTWSFSLFSDPSQILHTEELQDSGENDGKDIIATENSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPR6</accession>
    <name>A0AAV4RPR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_437521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008371">
        <property type="protein sequence ID" value="GIY24248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY24248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8175" checksum="1E0F4458F060DDD1" modified="2024-11-27" version="1">MQNSRKSTEAPGSNHSEISMGGSNRLRNLSAISNEMEENKSTAPLQKLRCIDKASIAVLMLLCLVWFRVIQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0S0</accession>
    <name>A0AAV4S0S0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endothelin-converting enzyme 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ECE1_0</name>
        <name evidence="3" type="ORF">CEXT_17201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008750">
        <property type="protein sequence ID" value="GIY26954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0S0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF133">
        <property type="entry name" value="PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="2">
        <location>
            <begin position="49"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY26954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="491" mass="56665" checksum="60FBBBD27DD2C9D5" modified="2024-11-27" version="1">MAPCENCNDMSEIQQEKLSQEECQRICYSKECVVAANFILENMDVTADPCEDFYTFSCGKWIRQFSKEDNYSVVDGMTTTLQLDLKDLLEKSKGEPGSTEEKLKMMFDSCTDERASEWNSKSEARKFLEKFGIRNWPNLPNDFQFNASLDETLSIMAAFNEFAFVTFKPTYDEPQESVADNNFRKLTISPGYPLMRDESESDVYEAVLLGILRHFGANSEDADEIWTEFKTIDFSLLSLLMETSAKVRYGEDEQELLEPLNCLASIEDSMHIWKREHYVRNIFSLVTNFTQKSVGNYLALRFILNHQRDLDGFLRALGAELPDVYPLDSNRRGSSLKLGVLHQVDVPLHVLPTGSTIRQRGTARKAHGRDSERRPHLHLRRRRLRYEAKVDEESPAKKTENLKYPGSSLLAVSNYHSVRDSSWSFQMLTDSVHDSLLTPFKCSQRVFAIVVQGFLKCFAKIVRDRSSWPFEILTKSVCDRRLFEMFRKECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6C0</accession>
    <name>A0AAV4S6C0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_491751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008829">
        <property type="protein sequence ID" value="GIY27558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6C0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10165" checksum="259C16B42B065FCF" modified="2024-11-27" version="1">MKKRCHYFNQRGVTVLGNSQELHLCNSQPFFPNYSSPTEGLWVYEIIMPIVWYCLWVPSQLPQFGNPMLLVRWKLYNRNSKIKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SED6</accession>
    <name>A0AAV4SED6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TATA-binding protein-associated factor 172</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BTAF1</name>
        <name evidence="4" type="ORF">CEXT_159161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009537">
        <property type="protein sequence ID" value="GIY32713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SED6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044972">
        <property type="entry name" value="Mot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022707">
        <property type="entry name" value="Mot1_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498:SF1">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12054">
        <property type="entry name" value="DUF3535"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mot1 central" evidence="3">
        <location>
            <begin position="607"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="Mot1 central" evidence="3">
        <location>
            <begin position="736"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY32713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="772" mass="86755" checksum="C2BEDB7922602CC0" modified="2024-11-27" version="1">MAKEYIKIIPQSEDDHMIATFIVFFLLLDTGSSPLTRKAAAIQLGEVQKLHPHELHNLLAKVRKYLYSSNWDTRIAAGQAVEAIIKNIPEWNVQCVKQEKQSSDLKNFSLTGRMKFLEFDVNKVIQNGSNLLACDGSKIDLYTQSILDPKEHLAKQREILNKHLGLNFSIMGLDSNYISKEDLEINLTPSPDEANIKQETKVDGTDRLTNETSHLSLNCIKTENSKNSEPPTKKRKTSAASFDEISFENNTNMSLWEETKQWPLESFSDLLVHDLLNAGWEVRHGAATALREIIRIHGKDAGKRPDVTSDQMEILNQLWLEDLALRLTCVLALDKFGDFISDQVVAPVRETCAQVLGTVANIMTVDRVKRILEILLQLLARPEWEARHGGLLGLKYILSVRTDMKELMIPLVFEATCLCLKDDVDDVSAVAASALVPVTNIIVSTLPDKVPSVISSLWDALLDLDDLTVSTSSILQLLASLLSYTATNSLNSCLTNLENLVPLEPLIEIHHFLYDAWKNLIIYAPLVAVIACTIPLLSTWVSMLMQPANVPYDPNACNVWLDIPHRMTDKVLGRNRNSSFTKATQEAYYLGGNHAGTENSKREKKHFALILNEWAKYDENLCPLPVKEKCLECLNETIYFDEIASAFTRLQQDCKDFISVSKHYSVPLDLSFQTGIVYTFEQIIHLATIASTAFISVKLKPKILETLEDRRKSLLRSANQASSDQASLTAFNGFNKREENELLQQASAHHLVNLMELCLTRANCPNSKILKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGU7</accession>
    <name>A0AAV4SGU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_461021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009525">
        <property type="protein sequence ID" value="GIY32564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="37" mass="4430" checksum="4C5CB898C89BF614" modified="2024-11-27" version="1" fragment="single">MLSELRLLYIQIFSTTYDQLKMSCEGCSLRFTILKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SI93</accession>
    <name>A0AAV4SI93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_24451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009693">
        <property type="protein sequence ID" value="GIY33825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SI93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="405" mass="45763" checksum="76E134BA4F472766" modified="2024-11-27" version="1">MNFFEDEENILSDQSEKDSSDEDSQEDTEDVVLKELLSKGCKEETNGIDVSETRNYEGFVNDSQDPMQFSLPSYQPGGDLKNFPVDSQDPMQCFSLPSYQPGGGFQNSVTENDLKRKFTDSNINDSEIHDTDNHSQEEEEGMFDSVLKEIGAEQFSSQDSDERVVIQGWNSLPYDENEGSQFGDEALQFCSGKFVSQDDAIPWTPSSSLYLKSQVSNKDGLCSPTLSMPAEDSDKLNESESKHSSPPAKKRKLFLDEKILNLENEDNLSISTKIENDTLKKSQIDTYSCKEYKSDDDSEEEEEIIRPTKKVKSSLAGKLWDSDDEDEPIEHSKFNGVSNKEHVSGDDSGEENELDDNLSESSNKDMDYFKENNSMKDDRDLYDEGIPDKQKQNGLEEDAGKKFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SK64</accession>
    <name>A0AAV4SK64_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_767851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009674">
        <property type="protein sequence ID" value="GIY33704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SK64"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11308" checksum="DA9C69709E176262" modified="2024-11-27" version="1">MQPIHEELPQGKTAITLRVAFLKIPNSIRRTMRILFLHAETRAAPEICLPPPISGSCRPSPLSPRRKGCRRPTAEFPAPSPSSRKTAIFTRLTICHEGRKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STT5</accession>
    <name>A0AAV4STT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_272641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010132">
        <property type="protein sequence ID" value="GIY37180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12660" checksum="176D220CE685EA5F" modified="2024-11-27" version="1">MRFQKTRPLHHLLKDPLQHLLQAGSEGLNSSKERQLAQKIILCWRQKPTAVFAERAASTPIDRLPVMKWNVLREFHDPPSYLVLHEEEEEKKKLGACDSNVCGMMIKKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUG7</accession>
    <name>A0AAV4SUG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_726181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010013">
        <property type="protein sequence ID" value="GIY36125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9033" checksum="5481ADE1C59C89F0" modified="2024-11-27" version="1" fragment="single">TILTSFNLTFTTADSAANTNIRESTPNEDIQFELIRDKQTDLQIAFQRGAGNKRFIKDLIKKTSLKISLTTEPSAFLPSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZ86</accession>
    <name>A0AAV4SZ86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dipeptidyl peptidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DPP7_0</name>
        <name evidence="6" type="ORF">CEXT_128861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010505">
        <property type="protein sequence ID" value="GIY39758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZ86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF38">
        <property type="entry name" value="LYSOSOMAL PRO-X CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY39758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8703" checksum="B81AEA4F337D39D1" modified="2024-11-27" version="1">MLSIGGEDISSATNIVFSNGNLDPWAPWWSVIVEGGAHHLDLREDNPNDPQSVRDARNFELANIRKWLTEYYNKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3I1</accession>
    <name>A0AAV4T3I1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">RanBP-type and C3HC4-type zinc finger-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_202222</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010593">
        <property type="protein sequence ID" value="GIY40289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3I1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071797">
        <property type="term" value="C:LUBAC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097039">
        <property type="term" value="P:protein linear polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20345">
        <property type="entry name" value="BRcat_RBR_HOIL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd16633">
        <property type="entry name" value="mRING-HC-C3HC3D_RBR_HOIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000137">
        <property type="entry name" value="RanBP-type and C3HC4-type zinc finger-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047558">
        <property type="entry name" value="BRcat_RBR_HOIL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047559">
        <property type="entry name" value="HOIL1_RBR_mRING-HC-C3HC3D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01053">
        <property type="entry name" value="LSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF13">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="608"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="149"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="153"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="402"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="406"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY40289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="73955" checksum="ABD555CE022D46D5" modified="2024-11-27" version="1">MELIEILLRIVVLLALGLIYFIRLLISYYKVHYIQLIFSLSFPFLYAVIEQNCFEILGSFQSKYVPFKLGVSAILFMIIGMFTTCMGNLISNSITSNKSYCRNKTLQKIISSKKSHKDKQNRIKKNSTKKATYYELMAIGDADLVNNSEPFICHICFSNVEIGEGILLQDCLHNFCRKCLIIEIRNSDSIIVKCPLKFICIPVRIIFEKEKLKLVSGQEYEHLLQNSLSIAESQASNSFHCRTLDCPGWCFFENNVQTFFCPACKRINCLTCKAIHEGLSCKQYEEQLEDDDDSYEDAYDFLQTFHCRTPDCPGVYLFENNDEIFHCPACKRTNCLTCKVIHEGKTCQQYEEQLEHDCESCEEAEEFLQSEHYKAWGNEYIKRANYDALVALDDADLVLNMKPFVCPICFLDVKTNEGVILQDCLHGFCRECLSSSIEYSEEAVIKCPFLDDVYSCESYLRDREIKNLVSPDIYDHILQKSLALAESQAENSFHCKTADCRGFCFFEDDVNTFLCPVCDKTNCLTCAAIHEGKNCKQYQDEFMKSEEAKKTKKYFQGLLKSGDTMNCPQCRIFIMKKSGCDWLRCSMCHTEVCWVTKGPRWGPKGKEILVVVANVSGTMSVAIQIVAIVTKEKRRFIGIDGKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T999</accession>
    <name>A0AAV4T999_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_111541_1</name>
        <name evidence="2" type="ORF">CEXT_508651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010795">
        <property type="protein sequence ID" value="GIY42066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T999"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044011258" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25196" checksum="E9C36BB38478AA62" modified="2024-11-27" version="1">MRTLGLVILAFSIGMLKAHHICRKSDSEACLPEDRNPPPFPGTEEQLQDACKFFRNVLQCLVEYVDKCGARNVHIMDATGGRLDRIIETHQEICQASSLQTDLVESLPCIKNIIENDDDLCQERTRNAFVQLQRTMADKVTTGQNNIFEVFDCLFPVLHINCFAIQTETKCGSRARNTVLAIIQGLELLNEECLDTMRDEALEMLEVIEFLTDQKIHVKNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFS9</accession>
    <name>A0AAV4TFS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011117">
        <property type="protein sequence ID" value="GIY44261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12448" checksum="E0E7024F440E029F" modified="2024-11-27" version="1">MDGVPFSCRNGIIRGTMPESNLKTLAQSLLYLLLKIEYSVVRNSPIAFSHNSSVYFWKTVTQGLLKSCLRGVWASYFHKTIVPPCPLSSGWNSENDHATVAEPKNGNLMGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMX4</accession>
    <name>A0AAV4TMX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_524681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011258">
        <property type="protein sequence ID" value="GIY45303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="5695" checksum="741F48471BD3F5A6" modified="2024-11-27" version="1" fragment="single">ESLGGVDAEVERCAKQAVVTARNRAGSTQGEGSERGGGKGVKKEVTVRIVWQVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUA9</accession>
    <name>A0AAV4TUA9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="7">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MAP2K3</name>
        <name evidence="11" type="ORF">CEXT_207941</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="7"/>
    <dbReference type="EMBL" id="BPLR01011841">
        <property type="protein sequence ID" value="GIY49469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043068">
        <property type="term" value="P:positive regulation of programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051403">
        <property type="term" value="P:stress-activated MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000040">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF11">
        <property type="entry name" value="LICORNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="49"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY49469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23128" checksum="02EF50306273F8BF" modified="2024-11-27" version="1">MMAGKKRPPKFQFVEEIKPPEPIAPPRNLDTRTTITIDDRVFEVEADDLEPMGELGRGAYGIVEKMLHRQSRTEMAVKRITATFSFYGALFREGDVWICMEVMDTSLDKFYPKVFNNEETIPEEVLAKVAFAVVSALHYLHSKLRVIHRDVKPSNILINRGGAVKICDFGISGYLVDSIAKTVDAGCKPYMAPERINPAPNQKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVQ7</accession>
    <name>A0AAV4TVQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_277831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011802">
        <property type="protein sequence ID" value="GIY49156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="16723" checksum="99E5E071E0D652F6" modified="2024-11-27" version="1">MVTDIRQTCPINDFTDMLSSVTNSPVFRYVVTSRPSAPASAQKHGCNPFFLVLASNCSLTEFFCSTLLHRGTSGHEATFTDSLYLDETTFTDSLYLDKAAFTDSLYLGEAAFTYSLYLDEAAFTDSLYLDEAAFTDSLYLDEAAFLQTPCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1C1</accession>
    <name>A0AAV4U1C1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_719451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012130">
        <property type="protein sequence ID" value="GIY51593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1C1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9489" checksum="596340E8786701A1" modified="2024-11-27" version="1">MKYGVLTYSEGRQSPNGSIIGEMKCGVLTYSEGRQFVNTKTRRMKCLSASLWMHGDIFNEDKSQEIEIHRRVYIVKSQLLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1J0</accession>
    <name>A0AAV4U1J0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LRRCT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_97590_1</name>
        <name evidence="6" type="ORF">CEXT_347381</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012129">
        <property type="protein sequence ID" value="GIY51579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1J0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF96">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043641005" evidence="4">
        <location>
            <begin position="20"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="LRRCT" evidence="5">
        <location>
            <begin position="266"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY51579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="311" mass="34872" checksum="245E8AFB238A3436" modified="2024-11-27" version="1">MWIITAAVLIIALFEYSVAGSCPPELATRPCKCKVEDNVVVLICANITDETVLEGVGRRTAGAIFDTFILRNSRIKSIPVSFSHHNLTTLQIEDSSLESLFDLSLCASNAITTISLLNVNFEGGFKWNEVKPSKKLRSLVIVRVTISGLDYDFKNDVSKDLEYLLLNETKIEKIDDDIFREFTKLVVVKINYSGLKTLKRSYFPSPCEISVLELNGNQIAILPDDIIEYMPHLKAFEVSNNEISEIPQTMFSILKHPLISIKIEGNPLNCGCNLRWILSIEKLNVYGNCETPARLKGKPLQNLTTADFICH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1M1</accession>
    <name>A0AAV4U1M1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_712611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012144">
        <property type="protein sequence ID" value="GIY51693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="14514" checksum="BFEE6896308D87DD" modified="2024-11-27" version="1">MVREDDKRFAITWKIKNFWYFWKTKRQTIESPEFYAENVRQTKWILQISEEDALLSHFTVVIKRAEEDYGPASVKLNLKICVLSNKGLTLKREWVENTESSKGTEKELQKLLERAALFATRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7C8</accession>
    <name>A0AAV4U7C8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_364561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012389">
        <property type="protein sequence ID" value="GIY53673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7C8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8766" checksum="3DF28AF8C120CCDB" modified="2024-11-27" version="1">MHFEYGYRNYFGCSDNHREKKSEDMHEHRPSQGETMAKCGHQKPGTYPVPLYNHPPANSFQVALKDQKLFSSKHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBJ3</accession>
    <name>A0AAV4UBJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_372971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012612">
        <property type="protein sequence ID" value="GIY55149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13277" checksum="0AD9E1679D072D67" modified="2024-11-27" version="1">MPCTRTRLLCCCHLDAACTTRPSQSRNRLADRFLCPCCTLLPSPHPGNRVRPLFDSPAKTRVIFAILSLTFLSLPTVLGRAAASGAGVVWAACVCKFQVDFGGCYVEIKVTKWNRNCWWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UF81</accession>
    <name>A0AAV4UF81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aquaporin-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AQP9</name>
        <name evidence="10" type="ORF">CEXT_233462</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012762">
        <property type="protein sequence ID" value="GIY56375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UF81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY56375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16868" checksum="8DF40519D2E62DD6" modified="2024-11-27" version="1">MVATYTRTDIAIWNYFYGKIVAGGLLMFTVMAIVDSKNLNIPKYLWPVFIGFMIQVTAQVFCLNCMAPINPARDFPTRVFTAIAGWGSETFGVRNYGYWWIGIVGPHVGCVIGAWFYYLSIELHWPEKKDELEDGDIPLSIEGKDRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UG85</accession>
    <name>A0AAV4UG85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012810">
        <property type="protein sequence ID" value="GIY56776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UG85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18250" checksum="FCA7023BF8BE4099" modified="2024-11-27" version="1">MVWVGRGEFYLVMWKPNNRGVSHPKGTSRSLCSGVFPGNCYAIRVLLELDEESYRNGLTEMRSSIDNHAFEERFFLAPKSLIRETEIVHSYVRESSAASTAAHPPPLPGAQLPPAQRSLGDAETLLSSYIHPLLFLSSPCYSSSGTRMLYALKKGKSFLTANGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAE8</accession>
    <name>A0AAV4VAE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_745311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014188">
        <property type="protein sequence ID" value="GIY67028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9607" checksum="3A59B899E1BFC1D2" modified="2024-11-27" version="1">MGNGILNSSRNDYHCDGTCNCVQNVPLFRAFVKNTSNDSLHLNNGPTHLEKSELSLIKTLGSGRKCIMSPNNREWIITDDLANVSASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VC70</accession>
    <name>A0AAV4VC70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_452681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014243">
        <property type="protein sequence ID" value="GIY67469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VC70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12441" checksum="B83A934ED716A843" modified="2024-11-27" version="1">MHCRFHHGHIAAACQEEHTTGLWKRSGVVVTSFTHCLTPALESTPQTIRERKNNRSRERKRATGPSWILINHLGTVRPSWIFANRLNPHPSFSRIRHNGSDATEISILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VD54</accession>
    <name>A0AAV4VD54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_287131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014303">
        <property type="protein sequence ID" value="GIY67948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VD54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10528" checksum="13BFB77598760D71" modified="2024-11-27" version="1">MVSESHIYHVTIRKESVEQRHSFIIKPFADVQKERSTTYRISPFGKYELHYSDFSTERIRPPSTLCRVSNARMTSCRTDLTRRQMTSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDI4</accession>
    <name>A0AAV4VDI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_425461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014261">
        <property type="protein sequence ID" value="GIY67623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13616" checksum="C4195E3085B574C9" modified="2024-11-27" version="1">MVSFSSSAQNDQSRQLIPCCHHSVPSVQGGQKPPWAIFRTILRVKFGTKRYRCRSPISNRKFQVEGILKSLKLPQPPHGNFTNHRLSNKMIQLVQEEEKEVSRTEPKENMIVYHSNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDQ2</accession>
    <name>A0AAV4VDQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_295331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014311">
        <property type="protein sequence ID" value="GIY68009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9659" checksum="ED02FA49D3D8EF9D" modified="2024-11-27" version="1">MRLNYSTRQLLKSEAYPLVRRLYNKPPYTIVASVCEMTSLCVKGRKTSLHVQCHLSHLKCQIQHFYGISSGLSQPNSSIRMRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEK3</accession>
    <name>A0AAV4VEK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_534331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014376">
        <property type="protein sequence ID" value="GIY68439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15807" checksum="84B7A125F44D6672" modified="2024-11-27" version="1">MYVDNCVASVKSEADLTKFINESREIMALGKFELRGWQHNSFESLRDNCKESQNASHILQDIQLELLGCCIDLRLAKTICTDLEELGGIPVYYWSDSMNCLHWIKNDEQWATFVMNRVKEIRSGSEPLQWNYVPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKX2</accession>
    <name>A0AAV4VKX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-related protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ACTR10</name>
        <name evidence="3" type="ORF">CEXT_260291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014756">
        <property type="protein sequence ID" value="GIY71106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10207">
        <property type="entry name" value="ASKHA_NBD_Arp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY71106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="328" mass="36798" checksum="CC0D556750CF9B99" modified="2024-11-27" version="1">MPMYETIAVVAEKHSVILDIGTAYTIWNYQAKDDLYVVLKEFIHRLYFKYLAVNPKDRRVVIVESVLCPTLFRNTLAEIPSLVYVPSHLMALFTLGISSALVMDVGYSETVVLPIYCGVPILNTYESLPVGGQLIHRRIEAELMENAYIKTSSPNERSLAEVLSEPLKESVLEDIKVRTCFVTPRARGLILQAHEGRKRIKGTASPDPELEVPTPPPDVDYPLDGEKILTIPGTLREWAAELLFEQDADSKSIATLILDSLLRCPIDTRKELANNVIIMGGTAMLPGFRHSLLTEIKMLLDDPRYSSRLPLKEIKIHNPPAKENYVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VS03</accession>
    <name>A0AAV4VS03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_228301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015034">
        <property type="protein sequence ID" value="GIY73112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VS03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY73112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18218" checksum="55DFB507D28B7FD4" modified="2024-11-27" version="1">MNHDIDMQIVELFFLQIALIAALCAVAVASHHGHHEHHHHHPQPYKFGYDIKDHHGSQHRHEHGDGHGHVQGNYGFTDHRGIHREVHYVADHHGFRATVKTNEPGTANQDPAHVHLHSNAHHALHHDGHHGHHHHDNHHHGHHHHGHANVYHHQGHHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZ58</accession>
    <name>A0AAV4VZ58_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_122031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015365">
        <property type="protein sequence ID" value="GIY75581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZ58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9816" checksum="CE18763DD7BF7D0F" modified="2024-11-27" version="1">MLHNLRAKVARKWKKIGKHAHSFPPPSFPPCMRVTRCVMVSMHLKEYTLATFAVDDSHNTSLYNLAMFAAADSPDTSLYCTLLPYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3L2</accession>
    <name>A0AAV4W3L2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_751391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015580">
        <property type="protein sequence ID" value="GIY77141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3L2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="25691" checksum="A90DB7BA6E44645E" modified="2024-11-27" version="1">MTKKLNPDFYYQWHEPFESVVHFFKATLLQVGWGEDNTKEVVMDVGCGPGETTTQLILPLFPSLKKVIAIDKLHDRIALACAQNFHPAIQFSVADIEEGIFLRSNSGNSKNPKWSFYFQGFEEYTPDTHQKEVTNSYSSDHDFKSFFLSICPLTPHIPDHRKSEFEEDFFQELLKLDDNRIQGTARRFGLNHSSMELIKGKATIKKEVHHHSQDVQLATDKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6X5</accession>
    <name>A0AAV4W6X5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_172701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015583">
        <property type="protein sequence ID" value="GIY77160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18486" checksum="5165F367B1E22706" modified="2024-11-27" version="1">MYQRDIAQAIDTVFRFFLQPRRIEASPRSLWRARIGKDLNCFRIARFPGLGKKRDESFLTLSSRKKSPLYSLGLLSPTQTNRSTATFSMASKDRKNLNCFRIARFPELGKERDESFHPVFVRKNSVSSPKRKLHFGAIYQSGLLCLQFLDENGLQYFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGD0</accession>
    <name>A0AAV4WGD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_425061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016165">
        <property type="protein sequence ID" value="GIY81802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="16146" checksum="9B5454E6BC2FC37D" modified="2024-11-27" version="1">MTNFPINWDLRLTNTPHPWRNGYVVSELILNNEWAMVTLWSDNRTINIGHRTLAPQYVEIYRKSTTGVVLVSGTLKLTAPSHQWHEHVVIERKIFQLMEKGSNYIIIELLDSTYQENYDPNKLTGNIRIESRKTKHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRV6</accession>
    <name>A0AAV4WRV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_55911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016511">
        <property type="protein sequence ID" value="GIY84409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12927" checksum="D081D3BE6C56A642" modified="2024-11-27" version="1">MIRFCRNSKLEKSCRVTDILTPDELKEAEKRILLIVQRTSFVSASGEKLRPVQRLYSLQINAVSSEPLRHRALKGTRKLSQSTEKNQRNKIADPQKSKVDNQPVLTPRNQIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTA3</accession>
    <name>A0AAV4WTA3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Trafficking protein particle complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRAPPC5</name>
        <name evidence="11" type="ORF">CEXT_775821</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 10">May play a role in vesicular transport from endoplasmic reticulum to Golgi.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Golgi apparatus</location>
            <location evidence="2 10">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016610">
        <property type="protein sequence ID" value="GIY85049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000005">
        <property type="entry name" value="Trafficking protein particle complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY85049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21417" checksum="06E46DFA3209295F" modified="2024-11-27" version="1">MSSIIRTLPKVSILDKPLSKGRSEINISAFALLFSEIVQYCQSRVLSVPELQAKLSEMGYHVGQRMVDTLFVRERNYKRETKLLNILIFIKTTLWKTLFGKEADKLEHANDDKKTYFIIEAEPLVNKFISIPKDKGSLNCAAFVAGIIEATLVCCNFPAKVTAHWHQGTTFKIIFDQSVVARDHPTDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3L2</accession>
    <name>A0AAV4X3L2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Optomotor-blind protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bi_1</name>
        <name evidence="2" type="ORF">CEXT_14271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017159">
        <property type="protein sequence ID" value="GIY89132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3L2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="363" mass="38335" checksum="02854C05533FC32E" modified="2024-11-27" version="1">MVCGSSLFSNVPIPFPRRQAMLLSQQRSQSPHHSGAQHLPSSTSGAGAHHDAEESSDDDEKVDVGGTADLQASVASLSCGKDDVSSRDERRENGCTKDRDDSNDDSMEKPLSSLNNLEHNGSSRDYKNECLDSLSGLPKISATECDRRPWHATPTSSAVFISTSFVLFEHEPFTSFTAFPAWSHLFLRSQSSLPLSLFTSSGHPSPAAFTASHLAQSSLNSSSQGVGSLPSMGHNLFAECSTGVCCRSPMFHGYPPTHALDGSLPTGASGNGGLLATAGTVGGKVKSLRFSPYPLPLTTMTSTTPATPLTVPNRSDCGSSDGSVGPSSVSSSSDLKNIENMVNGLERQQEQLAAETLTRLTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCV8</accession>
    <name>A0AAV4XCV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017515">
        <property type="protein sequence ID" value="GIY92273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8046" checksum="EDF4DAF95CBB1C88" modified="2024-11-27" version="1">MSLVKVTLVKGNAERARTTFIEVIAAIKARLPQFLFGTSSVVYQEMINAEMSLVKAAFVKRNAKEQERLSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XED6</accession>
    <name>A0AAV4XED6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_305171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017529">
        <property type="protein sequence ID" value="GIY92370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XED6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13445" checksum="741C0B484E66432C" modified="2024-11-27" version="1">MLHLRLFLRCDTKTFPTNLMSPPYLPYPLPPLGKGAKYFNVISFFTSSPLCLCHRKDEESVLVKSLDCYCSLTRALSGSGLVSSLQRHPLHPQGTFSPLLDLPWIFRPHLRPPPYTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFL4</accession>
    <name>A0AAV4XFL4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyl-CoA-binding domain-containing protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">acbd6</name>
        <name evidence="16" type="ORF">CEXT_682431</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017729">
        <property type="protein sequence ID" value="GIY93997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119:SF0">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 14" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="12" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="10" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="13" id="KW-1053">Target membrane</keyword>
    <keyword evidence="7" id="KW-0800">Toxin</keyword>
    <feature type="domain" description="ACB" evidence="15">
        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="14">
        <location>
            <begin position="161"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="14">
        <location>
            <begin position="194"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY93997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="28031" checksum="6A7D54F18FBC8AC8" modified="2024-11-27" version="1">MEDDDFPESCDDALENNFKLATDFVTENASVMQQDDLLYLYGRYKQAINGTCNEPMPGILKFKSRSKWSAWHNLGDMTKEEAMKQYIEKVKKISPDFDSSFRKKNQKKSHFGPVNSSCQKTDIELKEDAKTVFDFVKEGNLNRIKESISTNSSCKNCCDENGLSLLHWACDRGHIEIADFLISSGLDMNCQDKDGQTPLHYASSCGHEDVINLLLKKGVCTNIYDADGLSPADVAYSTTVKELLITNHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGT4</accession>
    <name>A0AAV4XGT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_369341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000386">
        <property type="protein sequence ID" value="GIY94401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9264" checksum="BFE361C2327E91A1" modified="2024-11-27" version="1">MGFYTVFCFADDGLNSAAAANQAPETAREIVLSLPDWFPKRYSIIKILVCRSFKPKTALTLWNIYRIDKSLLISAISTLITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJV5</accession>
    <name>A0AAV4XJV5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein Wnt</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">WNT7B_1</name>
        <name evidence="10" type="ORF">CEXT_760881</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Ligand for members of the frizzled family of seven transmembrane receptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
            <location evidence="1 9">Extracellular space</location>
            <location evidence="1 9">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Wnt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000456">
        <property type="protein sequence ID" value="GIY94959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005109">
        <property type="term" value="F:frizzled binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005817">
        <property type="entry name" value="Wnt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018161">
        <property type="entry name" value="Wnt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027">
        <property type="entry name" value="WNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00110">
        <property type="entry name" value="wnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00246">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 9" id="KW-0879">Wnt signaling pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY94959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8597" checksum="4251992BA5DBB494" modified="2024-11-27" version="1">MEVVRITAVLNTVQTECKCHGVSGSCTMKTCWNTLPQFGKTGDYLMRRYHEAKGCSPIGDPPKTPSLPQGEIDLILKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKI9</accession>
    <name>A0AAV4XKI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_747211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000487">
        <property type="protein sequence ID" value="GIY95188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8981" checksum="C6B90DCC56D73AA3" modified="2024-11-27" version="1" fragment="single">MVLLVTIPSHGKSKSSILYLIAKKSISRITQTIGGCRRCKRILIGCTTFFPDDLESSDESTKKRLPTTPSTESEEGYTPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLR2</accession>
    <name>A0AAV4XLR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_540661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017878">
        <property type="protein sequence ID" value="GIY95165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8830" checksum="174AD40328387D42" modified="2024-11-27" version="1">MHLNVPPMLRGKSLWRRHLFAAILEDVEPSRFSRTVQSISSVEYQLTPEILQCQEDFARDCNEDSRYLQCQDFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNK8</accession>
    <name>A0AAV4XNK8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dymeclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">DYM</name>
        <name evidence="5" type="ORF">CEXT_738461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dymeclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017936">
        <property type="protein sequence ID" value="GIY95566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019142">
        <property type="entry name" value="Dymeclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12895">
        <property type="entry name" value="DYMECLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12895:SF9">
        <property type="entry name" value="DYMECLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09742">
        <property type="entry name" value="Dymeclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0519">Myristate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY95566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="711" mass="81766" checksum="6F33210363864207" modified="2024-11-27" version="1">MEVLFELLLEFNSAEDPCERTYEKLQIVTLRILIFLLFDCKNYTVYWLEMGTSSSSLHELQDNKYLQQFSGKESISPNDPFWNQLLSFTFAPPHSCADCRLLEDSIRPMLDTLLNSNPISGNVAALIKVFLIHSSELKAAVQCENKVFIWQAYNSLFILRCILKYFIETLGEEGTLKQLEDTQENRSDPSNASEPEKLLEAVINALFEIIVDISLDSKTYAITVEAVHSLIVLLSVQMFSTRPAHESVVYSVIMEGKCAIHSLLLIKTLLQYYSNQDMCPHCITAVEGGSIIAGLASGLWNVLTLNYAGKNSPKDVSSFTVLANQSLLLLLTLVNHCTNDKEMKNPYRAALFSFKNSNSTSESNSTNDITAFKFDYDMLFKTLCSTLKDDQTALLTYLLLHQNPNFRHYVIYSSEIYMFVLPLLKLLYNAPDKNSHLIYMTLIILLILSEEEYFDKHVHAFKLRNISWYSERILSEISLGSMIVLILIRTIQYNMTRMHDKYLHTNCLAALANMSAHIQNLHTYVCDKFISLLENMGKRYVRIIDQSKPVSQTTDDELLPSDLMQDLSVLDEVLRMLLEILNSSLTFQLRNNINLLYTILYKKSIFSMFRSNPIFQDIMQNLDIVLAFFSPNLESIEQSVSVLEVTEIIKSVSLQWSKEKMKKLPELKFKYVEEGQPEDFFIPYLWSVVFHSSDIYWDSKNILIFNPYKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPX6</accession>
    <name>A0AAV4XPX6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_414531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018080">
        <property type="protein sequence ID" value="GIY96718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="38137" checksum="28CA7B8CC2F81BCD" modified="2024-11-27" version="1">MTDDDKEYFQCKGKSKETIQEKLVAFWTDDYINGFTLNRKLITADRYASLLYSSAVDGNLVATKFFFQNISSEDSDVTVFDAVNVILKKGRHRDDFIFYEKGFGEVLNFLVPNMDEKNRTRIFLSNDKEKLYKYFLHYSRPIIFLKFVREFKAAFRVDLYVTLLVEILFKYLNGYISYNYQLFFKRFWQLIPKEFQNMISRFSPVGGTILIAVVKRKFPFMLEKSILFTYELSNRIKLQTSGVIRGSHLDKYKFFTYLIREGICTVESLNRVQDKFSEDLLDIGEEPPLVFNYFGLLINEIKNEPYKYKNLTMTELEPELSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR29</accession>
    <name>A0AAV4XR29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_430431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000647">
        <property type="protein sequence ID" value="GIY96344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17842" checksum="EBE1E9F966C2DFD7" modified="2024-11-27" version="1">MVYNGHQAMSRSGPFFLCRFRALFLRVGSTKNETDRGCRCYLSIRVIKKSHRSERRDESVSKSAADKVIKKSHRSERRTSRFSKAAADKGKLTDSEAAGTLEVKYQVFSFFSSFLPSSPPYLVVSAVPLEKRVEKWKKKKTLAQNQFEPVIYFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUE7</accession>
    <name>A0AAV4XUE7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018283">
        <property type="protein sequence ID" value="GIY98364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10827" checksum="4E71834321D4FB4D" modified="2024-11-27" version="1">MRVGDTSGSCFVWTGGAGQEVGAELTRRSSLLPKSGGKPLSWGERECSRKANCKIIRRVLKKMGCVRCLSLLPNKQSPLPARKPFFFSQSNRFRFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVD6</accession>
    <name>A0AAV4XVD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">p-selectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SELP</name>
        <name evidence="14" type="ORF">CEXT_602091</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the selectin/LECAM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018383">
        <property type="protein sequence ID" value="GIY99096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050350">
        <property type="entry name" value="Compl-Cell_Adhes-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002396">
        <property type="entry name" value="Selectin_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19325">
        <property type="entry name" value="COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19325:SF560">
        <property type="entry name" value="SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00343">
        <property type="entry name" value="SELECTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="EGF-like" evidence="12">
        <location>
            <begin position="137"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="13">
        <location>
            <begin position="174"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="13">
        <location>
            <begin position="248"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="13">
        <location>
            <begin position="328"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="402"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY99096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="487" mass="54792" checksum="38FD324A218BD297" modified="2024-11-27" version="1">MEIDMNHPFQSYGCPRLESPDLGSISCRQSEKNFESLHGRCLPGYHFEEEEDTDEITLECRGGTWRPRRNFPPCKSDGYCNLRIVGAGFFNCTTGMDGTLCDVTCDYRFQGRYHCYPGRNWNPPLPYCAVPKETDSGRTPCRCENGGVCDVRGRCECPARTSGEFCEHLEKEKATCPDPGIPRGGNRMNSDGTDASYPRILRKESPSSIPVTRDNLALQGTSFVTCRADGTWSAPRPRCIRSRVDPLAYCPDPGQISYGSRRNADGSSTRSSRIFSNGQSVIYSCNTGYELVGESVLTCMPTGRWSSTRPGCRRTRRVPVNEPKDGEKLCNNPGVNENTILTKPIMDSLRVQEFPPGTQLKYECTKGYEPEGPAIIFCLRSGEWTSLPPICRRITTTVKPTEPPSCRRPGVDVNGEIEDHPLLDPRKRGQTFPPGTELKFRCQQGYESSWACYPALHELWRLDFSFTYLPINTYNNRQGYYLVINSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZC2</accession>
    <name>A0AAV4XZC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_276191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018541">
        <property type="protein sequence ID" value="GIZ00437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12092" checksum="6B12FED3DDC493D6" modified="2024-11-27" version="1">MRSSNANLGTPSSNVHSMFSLRDADLTTVQVLESLLVVVEYLPLNVTTHEITMICVRRFHRFLRLDSGMLSGVICDNAEFLECIFYGSEGQEGKRRRTDIATLVRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y700</accession>
    <name>A0AAV4Y700_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001347">
        <property type="protein sequence ID" value="GIZ01761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y700"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7962" checksum="BB5C322B502FCA59" modified="2024-11-27" version="1">MTPHTWQHLSPFRHLGDNLGCELRQPNLFIHLNGMRWISREFKQLADAKFLWNGELGNIFFLSHCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9T0</accession>
    <name>A0AAV4Y9T0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_348561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018980">
        <property type="protein sequence ID" value="GIZ03649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9T0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13134" checksum="6C2E4E66AFA4EF3C" modified="2024-11-27" version="1">MHYGGRIVGFYLPQLNKDFCAACAGACCVGNNSEKSIPVRMLNQASARERASIPEKEKQEKGPFPIVLELNQGLRSGKSFQDCDGSSVSFHQQDFPFHSRCVCISLAHLARLSNTILME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBP1</accession>
    <name>A0AAV4YBP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_697181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018943">
        <property type="protein sequence ID" value="GIZ03411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8710" checksum="F7172CB8E37F2F1B" modified="2024-11-27" version="1">MMDEKYSWDNPYPVLFSPRAFKVPFGRAMPEIHVRDRYFIIWLINNLVFAWGLDHPGPNRLVHMALNEKLPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YF15</accession>
    <name>A0AAV4YF15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_696281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019135">
        <property type="protein sequence ID" value="GIZ04777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YF15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7756" checksum="A454AA3843343A7F" modified="2024-11-27" version="1" fragment="single">TAKTVKDAVLMSHYDVSGKQDSTVLRYRKHSCSNFNVHKEGKVISGPLDTLTAVMNSKCSFNLSRMAYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFB2</accession>
    <name>A0AAV4YFB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_737041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019199">
        <property type="protein sequence ID" value="GIZ05066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11477" checksum="DC85E3368AF584EF" modified="2024-11-27" version="1">MAGILHCLELSSMHHPEIYAATVKPDIWPIMENNLFRDSIRWHSCKKLLQHSKTIQVCKIVPVPTPGFFASFRTAALWDLSSLKRAIHHHQSQKEVFSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3Z4</accession>
    <name>A0AAV4M3Z4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_261002</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cleavage furrow</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019325">
        <property type="protein sequence ID" value="GIX66575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3Z4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032154">
        <property type="term" value="C:cleavage furrow"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000162">
        <property type="entry name" value="septin-7 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="7">
        <location>
            <begin position="23"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX66575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="283" mass="32988" checksum="7D5E401926725550" modified="2024-11-27" version="1">MKSDGEIGFATLPEQVHRKSVKKGFDFTLIVVGETGLGKSTLINSLFLTDLYKDRKILSVEERVDRTVDIEKTTMDIEEKGSQTPINSCGYTRIWRCYQLWKTIERYIDDQFNQFFKDESGLNRKNIIDNRVHCCLYFISPYAHGYFSKLYLEFLVNFFIFQIKAAGCGIYEKITPKVNIVPIIAKADTLTPIEIRKLKDTILREVEEHQIKIYQLPECDSDEDEEFKQQDKELKESIPFAVIGSTQVVEINGRKVRGRLYPWGIVEVENPKHSDFLKLRTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9E1</accession>
    <name>A0AAV4M9E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_508781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002013">
        <property type="protein sequence ID" value="GIX68978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9211" checksum="6741EFC2CB02D980" modified="2024-11-27" version="1" fragment="single">NRDRESSSRVSSILEKPERQNFKDTKLNLAAATLHRVHSCPAPSDGSISNGFASTPSVTTAQLLLQKMSHLALLSLSSLLIIPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDN1</accession>
    <name>A0AAV4MDN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_13961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002100">
        <property type="protein sequence ID" value="GIX69965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16230" checksum="1DF3E0611BD453C7" modified="2024-11-27" version="1">MNRYSTPKCKPLGKSGDFCLHENEPEDMILSLPNGKETYARGIYRLFCPCAESMTCFRNGSFQKNSVSFQDFSRNYRGLQRYSIPECTPKGRLGDFCREGAEPEAKILLYPNMRYLYLEKVWFEVAPCEDNLICFENVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGC2</accession>
    <name>A0AAV4MGC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chitinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">X975_00937</name>
        <name evidence="8" type="ORF">CEXT_729891</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002172">
        <property type="protein sequence ID" value="GIX70890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="264"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="414"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="617"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="756"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="467"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="670"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="681"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="732"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX70890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="945" mass="104480" checksum="4B1A4D9BD5089F4B" modified="2024-11-27" version="1">MSTTTKRPYSTTSTTTSKQSTALSTTNSPYSTTPITTSKPSTATNSPYPITSTTKMSTTTSKPYTTTTSTSTSRPYTKLSTITNSPYSATPTTSSKPSTTTNNPYSTTSITTSKQSTALSTINSPYSTTPTTTSKPSTTTNMMSTTTSKPYTAKFTTTNSPYSTTSTTNNPYSTTSSHTTKLSTTTTKPYTTITITTNSPYLTTSRTSSRPYTTKSTTTNKPYTITFTTTSKQSTIKSTKTNMPYSTPFTTTSKRYISTTSPPRRQCPEMNGIFRNPQNCGSFLHCSNWIPYIQQCPSGLHFNIEKQICDYPCDAKCDKNLNCTATAKPELSAPDPLPFCTKKGLLTLQKVFVDITSIALEYSLSNKNVLKGYILIPQKRVCDIPKIAGCGKLSKPLPSPDLYEECSCETCLSPSKYNCLEYFLCLNSTAYRMKCSDGFLFDKKLNTCNLANRVACDSTTTTAPSTTQYTRTTTNLPYTTEPTTSRPYTTESTTQTQYTTITTTAAGTTIIQPYTTTSKSHPITTMSTTTSTPYTSTALLQEHNQCPSGLHFNVEKQICDYPCDAKCDKNLSQVQRVAPSTTNARVANQQSEIVLEVRHLIPECPSVIGFIVSTAHTAKSVPEGTDYSPHKDDCHKFVHCANGIPYTKACPAKLYFDPATLRCTYASDKCVTSKSPGATEEESKSPDATEEESKSPFATEETSKSTVATEEESKSPGATEEESKSPGATESKSPEELKSPGATKEESKLYEPVEQKWKCPKGFGYYIHEGNCSNFYQCIDGIPSLKQCPEGLFFNSKLGMCDWAAQVNCLVDQSHLQRLCRRYDRKVDCPSERSNKPTLHCNMFYDCRTGDACARRCPNGLYFKHKHRCVTFQQMSSVRKVKGGESYSLKNMVELCYAKKRGHMADPASEKCYYKCHHHLVIRSCCSKNRVFNEQKGRCEWKYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPI7</accession>
    <name>A0AAV4MPI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_46451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002497">
        <property type="protein sequence ID" value="GIX74304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12374" checksum="485D41C683C2D8D5" modified="2024-11-27" version="1">MRCVEAKIPTPAAQRKWAEGNDNEKEEWKKRKWRGNIRKAFGSGSRKLEREFLALFNISRKGWIDTAVPHDIPIGRCKKNERGIFVGTQNGVNSNQKKPLPNRSMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQY8</accession>
    <name>A0AAV4MQY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">CEXT_566861</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002524">
        <property type="protein sequence ID" value="GIX74762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005272">
        <property type="term" value="F:sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX74762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9183" checksum="625F285E890B77B7" modified="2024-11-27" version="1">MVDGTLSTVEPEFRLDLMGVVVFYQTMSITNLSETSIYSWEFLIANIGGSLGLLLGASLITFVEIGEFIADFIIKMCRRRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MS56</accession>
    <name>A0AAV4MS56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_576011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020153">
        <property type="protein sequence ID" value="GIX75271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MS56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11729" checksum="12B1E62F3A9F3589" modified="2024-11-27" version="1">MVRINIYLSRSSEEFESYSRRLITPKKSLRKDHSLMLRHGLAMYASRILGLSACNRLYALCIHFCDMTLPLTFNLAVEPKGACHWRSLLGNWGKALAFTLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX79</accession>
    <name>A0AAV4MX79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_51061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002719">
        <property type="protein sequence ID" value="GIX77101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8070" checksum="51EF29EE273C4CDD" modified="2024-11-27" version="1">MIKKKKEPQRITAVVINHPSFAQRSRAANEAQMGFQSSHNRGIITCRKHGWLHKIPFVDPDEKSLGCIEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N209</accession>
    <name>A0AAV4N209_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_182251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020419">
        <property type="protein sequence ID" value="GIX78511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N209"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09276">
        <property type="entry name" value="Rnase_HI_RT_non_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="407"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="556" mass="64183" checksum="4F5E541D62E86AA4" modified="2024-11-27" version="1">MSFLQWNCRSLQNKKIWLHQPPFTTSEFWVFQETFLKADDRLSFPNKIFFRTHRNNRTGGGLLIGIPPNMSGHVIFENSNDPNLEMLAVEIQSHNVTFTIVNIYAPHGFDIHQVQNFFSTLKTRTFIFGDFNLHHPFWGGKTSTPKSEEFLDWLNQSHFSILNTSTPTHITHNFTSSVIDLTLCSAALLNEVYCYVSDCTFESDHLPIVVSWSKLTNATKYLKTIYWNPILRDSNNFLQSIADPTVEIVTEKISHTININTKNKILTNNEYPPWWNIACNNFCQLKKIMWKKARNSVSVPDWIRYKKYRNKIKRLALQFLIKQYANHSFSPLMVNNELQLLDKDENTLKNSLQNYNCSPEHLLTLPIVPRHDPPLCEIFLQKFRFQNKENPVSLIVNDFSDCINRFFSDHYIIATDASKSHVSTSIAGISCNQSFSYRINPINSVFTAEVLAICVAIDELAIVDKDILILSDSFSALNSLKNLNIHSTYAIQRLASKLFVRQTFNQNITFLWVPGHSEILWNEKADSLAKNTTELSQFIEWISPEDVIANLKNNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N395</accession>
    <name>A0AAV4N395_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_513371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002880">
        <property type="protein sequence ID" value="GIX78901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N395"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8805" checksum="40280B3B04206628" modified="2024-11-27" version="1">MYYLTKKLNQTGGIKVLIKMHLVLGCTFHFGAFVPIRRLSRPWKEGEDSESPINHALRAVVDDGGAFSCQEEFWHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5W1</accession>
    <name>A0AAV4N5W1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_543701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002958">
        <property type="protein sequence ID" value="GIX79650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5W1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7636" checksum="B9B1E3F72049D37C" modified="2024-11-27" version="1">MGSALNTSSMSLTLRVPAGSSITGLTCHRPTRMSLSALLKRIDCLETGLDLFICEDHVWIPWMNPLFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N808</accession>
    <name>A0AAV4N808_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_660161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020514">
        <property type="protein sequence ID" value="GIX79617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N808"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10794" checksum="229AE172D337C5D4" modified="2024-11-27" version="1">MVVKERGITVRKYAVLVSSARVENEGFSLLNFVFASLVLPAEIKGKNWEWGGRNSIRPHQSAAIAEPGTCPRRKQHLRLQYEKAIVSEIVAYSRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDZ4</accession>
    <name>A0AAV4NDZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_52461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020818">
        <property type="protein sequence ID" value="GIX82873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="39" mass="4661" checksum="4B310BA7AC9CC3D0" modified="2024-11-27" version="1" fragment="single">IVSPRRIRRAGEKQNSPSQNSQNFERTRLEFEMDEHGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE70</accession>
    <name>A0AAV4NE70_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein BUD31 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_441071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020831">
        <property type="protein sequence ID" value="GIX83080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018230">
        <property type="entry name" value="BUD31/G10-rel_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00997">
        <property type="entry name" value="G10_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00998">
        <property type="entry name" value="G10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX83080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="17065" checksum="5E4AAB07820B6AD4" modified="2024-11-27" version="1">MPKVRRSRHRPPDGWDLIESTIEELEQKMREAETEPHDGKRKVESLWPIFRIHHQKSRYVYDLYYRRKAISKELYDYCIKENIADKNLIAKWKKQGYENLCCLRCIQARDTNFGTNCICRVPKSKLEEGKIVECVHCGCRGCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NH39</accession>
    <name>A0AAV4NH39_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Core Histone H2A/H2B/H3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_398081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003356">
        <property type="protein sequence ID" value="GIX83674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NH39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000043">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="2">
        <location>
            <begin position="16"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX83674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13373" checksum="A5357ECB6FA40D46" modified="2024-11-27" version="1">MLMKTGVKDRIAKKTQLLKRKKRIESYAIYISRVLKQIDPECGISRDALSEMNFYVNFLFCLIVEESSKLVKISKRCTITERDIETAIRLLMPGELSRQAILEATRAVNKFMEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLK9</accession>
    <name>A0AAV4NLK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_175981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021086">
        <property type="protein sequence ID" value="GIX85682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050685">
        <property type="entry name" value="LDLR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270:SF62">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX85682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15319" checksum="7879F2FF25C96184" modified="2024-11-27" version="1">MPADQFASGQWTSFATPDNSGGTRYHPLSSSLVHSSEDRWATRFIASAIPRRSSRVKPSTSAYRRRYHDGWPDCDDGSDEECSRGQHRCRCGLPHCVDIHKVKDGVKDCEDGSDEDDKKNSTKRCPTKVDSKISWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM66</accession>
    <name>A0AAV4NM66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_577051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021099">
        <property type="protein sequence ID" value="GIX85861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13272" checksum="ECBD5EC6EBFC9593" modified="2024-11-27" version="1">MRYRIAEVNVDERRKLMNLEKEQKSNRTEVMQLTGEKMRSQDASPNPTKRRKIHRKGKIPTDHWTPDNGRNQEGKVASKKQKGKKKAFVFFHSIRLNKKGRYPPDHEKDFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPX4</accession>
    <name>A0AAV4NPX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_365771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003582">
        <property type="protein sequence ID" value="GIX86355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10843" checksum="69D799B9F8FFCB0A" modified="2024-11-27" version="1">MQVFKTINIHNGFNIPHPDDSIKSHGVIPREPDGYSVGKYRLLTAFVYLDWTTFIVRRKGHDISVAIKKSLPVVPEEVDYRNLHKPSLKVWISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NY84</accession>
    <name>A0AAV4NY84_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Maturase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_346551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021460">
        <property type="protein sequence ID" value="GIX89860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NY84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="36044" checksum="A55986D02F55E485" modified="2024-11-27" version="1">MLRFVNAKSVILIDLLSMEEVENAAVHWTCAGRVRPLKHPASFVLGRGRINALFQKEYYLLSSKLLSQLPPTPNKNSTLQPPHLLTRRYDDSSHNAKWREDFKSNSSSRTIRLEEFLHLIATWSKNVHGILIQPASRETMNLSSSFANGPLPVITCLAWRERGKSVAFASRMEVLIKWPGILNPKLDSNLSSLPEINASFVGVLKSECRPRSPILPEVLIVFLCPLTACPSSRSTSCYVPLHHPSIPATPEHHYRGLLSSSPPPHPPPPNPSKNGVPCNRIFGRTKHHYRGLLSSAPLVHPVPPPKSLKNGVPCNWISGTSELGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZ26</accession>
    <name>A0AAV4NZ26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_375481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003817">
        <property type="protein sequence ID" value="GIX89028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZ26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12231" checksum="FB03827F05CF280C" modified="2024-11-27" version="1">MPGGGGSTDCLAHNDFLPSSAAGFFPDLPITAIRLCRVHPSVFLEQMSAANDPEEVPPGSLPVFICIELNRGQTRENEWRPSFRRVRLIKTFEVFSEPFSCHGPVWGSATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2X9</accession>
    <name>A0AAV4P2X9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_767251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021577">
        <property type="protein sequence ID" value="GIX91378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13207" checksum="0EB62B3CB1E37FE3" modified="2024-11-27" version="1">MSFHSPTTEHNFHHPIASTPMNHSDILKMNRAKPRSRISSQTEGLVQTFLEMVAYIEIPWGVQKVQNSTLFRVLFRWIPNIPFLHLIPVNKDCAARKLLRGGDLREESLAQGVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2Z6</accession>
    <name>A0AAV4P2Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine incorporator 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Serinc5</name>
        <name evidence="7" type="ORF">CEXT_74951</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021498">
        <property type="protein sequence ID" value="GIX90365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX90365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14557" checksum="309D13CBE928408D" modified="2024-11-27" version="1">MFHIILKASNHVDEDGGQKVIRNEVERVVYNYAFFHVMFFLASLYIMMQLTHWFRPEQANLLTFERNWASVWIKMASSWTCIAIYLLTLFTPGLCPGRLNRSRSARNKDLELNRVRRDSSLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5N3</accession>
    <name>A0AAV4P5N3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_90821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004143">
        <property type="protein sequence ID" value="GIX92657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5N3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14794" checksum="5FDD1488240CB581" modified="2024-11-27" version="1">MHFSKYICRRSTKACPKRSTFSPEHIACLSFESLFRVKTIVHSSPCAEGSTDARRNDGRRRFIATIVDHEAGSFELIDGDAQLRNARVRIQEAELSASVHWVRSIAKKKKEDFIYTLLLYVSRRFVCIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8L8</accession>
    <name>A0AAV4P8L8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_100311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004132">
        <property type="protein sequence ID" value="GIX92511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7929" checksum="62F807D53E713986" modified="2024-11-27" version="1">MDKESYLLFLLLQSDITVSFGGADLRQGVASCGPLPIPEAEQRHGEETRRLATPLTPPQHSMTTESVNVDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8S8</accession>
    <name>A0AAV4P8S8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_397121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004250">
        <property type="protein sequence ID" value="GIX93451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8S8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="2">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX93451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7909" checksum="F25263A55C451EE3" modified="2024-11-27" version="1">MWSEWVSVGSRSPKGGVRPQLHTPKPPKTFLQLVWEALQDVTLIILQVAALISPRPRLLRITARPEWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBI3</accession>
    <name>A0AAV4PBI3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_554071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004218">
        <property type="protein sequence ID" value="GIX93254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBI3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX93254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9183" checksum="C8DE51E553981A2C" modified="2024-11-27" version="1">MLQRLAMTKRALYWSDVIVVWLIAVIGHWHPAPSYVTAESGQGPKHPGRHVNTEILASAWRAPLNGRRGKKGQNRDKGGKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PE83</accession>
    <name>A0AAV4PE83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Three prime repair exonuclease 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TREX2_1</name>
        <name evidence="8" type="ORF">CEXT_280821</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004516">
        <property type="protein sequence ID" value="GIX95431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PE83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040393">
        <property type="entry name" value="TREX1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13058:SF19">
        <property type="entry name" value="LD40940P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13058">
        <property type="entry name" value="THREE PRIME REPAIR EXONUCLEASE 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YprB ribonuclease H-like" evidence="7">
        <location>
            <begin position="17"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX95431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="25622" checksum="BB69616D20C62996" modified="2024-11-27" version="1">MMFPDSDPSCNSISTLIFMDLESTGLPSFVGKSNVHITELSMIAVDRTDLKQIAHLESYPKQTKFMYSSTPSVISVTAMTINRRPLCLLAHNGKKFDFPLLQAELRHINYALDPEIRCADTLEAFHSIVSSTNKIPMNSPCLSDNKRKEIDSNIKQDIRKSEKRAVSDDETDKLLSDDMELFTAIEDPYIVDMSDVPLQINSFLDKEFTTPKSKVNNCSEAEKPHKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNA4</accession>
    <name>A0AAV4PNA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_103571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004977">
        <property type="protein sequence ID" value="GIX98887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8940" checksum="148ECFBAECCEDD2C" modified="2024-11-27" version="1">MVQTPSNEMERRYFEVVWSSILRGLQKSYGDKGFVMRALTVERSGDGETPLRTKWNAAILKSFYPAFTGLQKSYGEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQX6</accession>
    <name>A0AAV4PQX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_623171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004879">
        <property type="protein sequence ID" value="GIX98234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11940" checksum="7C68763D463F3630" modified="2024-11-27" version="1">MDTRTRSPPTVGGAAAPLSESALALFKMLLVFMDDTSINFDLLLDAVTNALPALETTQDCHMKAELCELIVSDQILTSLEKELMRYIGIKQGKHGSSLSHWEENWICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PU60</accession>
    <name>A0AAV4PU60_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_299611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005079">
        <property type="protein sequence ID" value="GIX99696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PU60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="8257" checksum="817A7EA917E10120" modified="2024-11-27" version="1">MLTWLLMLCLNMLFVVLLKYDLVVYVIVMGSNGDLLVVNPGQRSVLGLLVYKWSTVFDMSSRCYPNRLPVGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q943</accession>
    <name>A0AAV4Q943_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_341131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005911">
        <property type="protein sequence ID" value="GIY05985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q943"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8145" checksum="2E4DB8AC65E6B42D" modified="2024-11-27" version="1">MGPQGGVLLSGRGQFSWAGDGCAPPTAVCFISRRHVTFYDDYLRPHLLSGALICATAMVSGVALPSQKVPVEVLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDE7</accession>
    <name>A0AAV4QDE7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pol_684</name>
        <name evidence="3" type="ORF">CEXT_568871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005929">
        <property type="protein sequence ID" value="GIY06131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY06131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18234" checksum="47C0540F6D67268C" modified="2024-11-27" version="1">MQTLYSDRGSNFLSAAMNEVYEKLGISKQHTLAYNPQGNGLVERLNKTLIDTLSHLVSEKQEDWCQHVPLALMAFRSAHHRSIQETPAFLVYGRDLQMPYDLIFRDQTVSELVLVRKDHSTGAGESPPQAVDDHSPPNSSTAQVAVSHRYNLRPRNAMGFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJ29</accession>
    <name>A0AAV4QJ29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_752251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006300">
        <property type="protein sequence ID" value="GIY08849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJ29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12011" checksum="85B94BF54BBC9D12" modified="2024-11-27" version="1">MGIESSGIDGGWRARSLRVSRWGVRVAPFRGHGSSSEAEIIPRTEADAIVVKPRLFRITVIIEMPYFFSFNARVHPLHIATDRRQGARLAAALPLSEKGYWMEERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSH4</accession>
    <name>A0AAV4QSH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_461771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006598">
        <property type="protein sequence ID" value="GIY11052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="62" mass="6692" checksum="64DAB26BD172CEF1" modified="2024-11-27" version="1" fragment="single">YALNLGKGFRYWSRAKGAAVTPAGENSGIEFIGDQSNQPFSGVIEKRISQFSLSSNSSYSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTP7</accession>
    <name>A0AAV4QTP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006813">
        <property type="protein sequence ID" value="GIY12595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11354" checksum="EBCED44CF1EBF1D7" modified="2024-11-27" version="1">MDNTGKQNKSETFPLVNTSRVFGAKKFSEIPSWLKLSLFLKVPAKSLEGTCFRTISSVFRNESFLFSSSLFVYLFWRFEISFLNHEIVMGLLISLKATC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVS0</accession>
    <name>A0AAV4QVS0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL15m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">39S ribosomal protein L15, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mrpl15</name>
        <name evidence="8" type="ORF">CEXT_599701</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006919">
        <property type="protein sequence ID" value="GIY13342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="7">
        <location>
            <begin position="71"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY13342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="272" mass="31196" checksum="2E2F1C16ACBE5B88" modified="2024-11-27" version="1">MPFSDNPALFEQCRRPRGQHGGGTHGHGKKGSKQRCSYPRVGFEGYQTPFYLKMPSENYYTHFRGQRQYPPLTLGQLQLMIDTGRIDPTQPIDLTTICNSQLYFLDPREKHFGVHLTDEGADAFTAKVNIEVQHAKETVIAAVERNGGVITTSYYDIESVIALKDPQKFFERSKPIPLRKFPPEDAITYYRDPKSRGYLADPEKIADERLALAQKYGYELPDISKDPEYEMLMLQKDPRQVFLGLEPGWLVNLADKVILKPTDELLQQYYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QX37</accession>
    <name>A0AAV4QX37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_617281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006932">
        <property type="protein sequence ID" value="GIY13394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QX37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11678" checksum="A212BF1ABC3CB4AC" modified="2024-11-27" version="1">MDTCASNSLRKRNSITIFKMADSIRDFNQPVGRMDFPLNMQADFFLRQKETFRRMEIEALAAVWAPNKFHGLVQDDRRVGSNCGLRSSTFEMASHFKISNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R043</accession>
    <name>A0AAV4R043_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_594591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006996">
        <property type="protein sequence ID" value="GIY13742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R043"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8242" checksum="31FCEAA39EE04DFD" modified="2024-11-27" version="1">MWHSSNPNDYTEIITEMKGLVCKEEVVRVYKFSLNAILERKTSDLELLPLKYRNCEYNPGMEDYFLYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2M8</accession>
    <name>A0AAV4R2M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_783061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007273">
        <property type="protein sequence ID" value="GIY15727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11264" checksum="A98389F3DA046267" modified="2024-11-27" version="1">MLEDTVNVKVLLSLLPVRNRDFGHKFYILPPTTRTPLLLRLSLTSAPQRKCPTFHFLARSKTLLQVKFSIFGIPQKCRRPYLQQRKREKKKNFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RE69</accession>
    <name>A0AAV4RE69_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_681281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007703">
        <property type="protein sequence ID" value="GIY18981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RE69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="9933" checksum="794F086D2920E35A" modified="2024-11-27" version="1">MIITVQNWLRVYTDGSATGVGTNAGAGIYLGVKSQQGRRFTNFDGGVAAVHTTLTEIANREQNTVLFNDSQATIRAISFAMPSKKKFCSANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4REJ2</accession>
    <name>A0AAV4REJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_414671</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007629">
        <property type="protein sequence ID" value="GIY18468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4REJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY18468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="22005" checksum="1EDA355BFE4E7737" modified="2024-11-27" version="1">MVWIHGGFLQFGSGHQKGLSPDGHLAKKMNVVFVSFNFRLHVLGYLALDSLFNNLLEDSRGNYGTWDQLVVMEWVRDNILYFGGDPKKVTVFGPDGGAASILTMMTSSYFRNTFRSAWLLGPAMIFNRSFTDSSHHNQGHFVDKSGCAMDVQCLRKMTPKEVTKLTFGTMMLPSELEIRMIYLFKNSTRTARRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGU2</accession>
    <name>A0AAV4RGU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_192751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007729">
        <property type="protein sequence ID" value="GIY19218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="48" mass="5894" checksum="485850AEBE106964" modified="2024-11-27" version="1" fragment="single">MGCEKQIREPEYPSFWLRGRKREEYGLLYHIPCRFCILLNCVDKMELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMK2</accession>
    <name>A0AAV4RMK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein 4.1 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cora</name>
        <name evidence="3" type="ORF">CEXT_111321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008026">
        <property type="protein sequence ID" value="GIY21515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008379">
        <property type="entry name" value="Band_4.1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280">
        <property type="entry name" value="4.1 G PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280:SF21">
        <property type="entry name" value="PROTEIN 4.1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05902">
        <property type="entry name" value="4_1_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 4.1 C-terminal" evidence="2">
        <location>
            <begin position="233"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY21515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="34220" checksum="B7641BB59759BA10" modified="2024-11-27" version="1">MEECQLLASRNRTMSESRTTDNKRHTLAGPIRSPIGDDFRKKDHQNIPHSTFVPGFETRLNLFSTWRVNGNLKTKTPGGIPVMPPIDPFRLNQQSPELTNGGNIRMSPDDNIRISESVVTQPLVSESSTFTTITTTESPGMDPSSPENIITCPIEELQSGIVKTESVMYNPNSKPCSPQNTTYVPVVETETCKVFYTSDLPQSPEIDPSVVLQMLLLFRRSTPLFLGEDILNTSSVSSKTRTVETITYKTEKDGVIETRVEKKITIHSDGDPIDHDQALAEAIHEATLMNPNLTVEKIEIQQQPPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV50</accession>
    <name>A0AAV4RV50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_495771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008454">
        <property type="protein sequence ID" value="GIY24811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8902" checksum="8AF178DA4F1CFBDC" modified="2024-11-27" version="1">MVVADIPARTSNVIEESKVRDKNVRIIIESFKSTQKIEDYANWTERSFVLNQKVLIDFLGNSHSYMALRIAEKAFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYX3</accession>
    <name>A0AAV4RYX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_321901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008524">
        <property type="protein sequence ID" value="GIY25332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="15887" checksum="5E3C2B323E1D0E44" modified="2024-11-27" version="1">MGPTDSSILSHNYSRKLPTNLLPSGQVASALAFRGHRLQSFLLCVLILSFSVICEATFQKLLMMLQPMSACPSNCCKAVKCPMPKCHPQQMMKPRAGWCGCCPKCMTQLRMGHPCKPKPKHPCPMMPTSECGRGLKCKQGKCCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3N1</accession>
    <name>A0AAV4S3N1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_196671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008978">
        <property type="protein sequence ID" value="GIY28740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3N1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12206" checksum="328E8A1D7207B2C3" modified="2024-11-27" version="1">MRMILNEVGNLGSRSLRGCWVYPFLLWRVPPRKLWASSVEGCVASLAVDAFFSPHSVEVCIRLWGGLRHKPHSELLESSFHCYDKNRSIFGIVRRYFVPFYFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S504</accession>
    <name>A0AAV4S504_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_675051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008822">
        <property type="protein sequence ID" value="GIY27492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S504"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11465" checksum="96BE316BB6A38EFC" modified="2024-11-27" version="1">MGPSPPEVCASMHHRQIMSHLPTPPLPKRGMRLGRGRLLPGRGSQLHTVKEGWVFLNKTIFFSRPFSRRINIFSAHEDFNNLTPHHKSEGQCACSPLTYPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S649</accession>
    <name>A0AAV4S649_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_599211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009114">
        <property type="protein sequence ID" value="GIY29698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S649"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12047" checksum="A174533B1068A755" modified="2024-11-27" version="1">MFSDTSRNHCQQDVPRGLSSSTPEKIKETLKEHKRKRKKAHIYRGHHFRSSTEPRPTCFAMLFEDDIPEELCCFFLVSFGAASNGIISKELFFLFIYCVEATIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6V5</accession>
    <name>A0AAV4S6V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_762631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008975">
        <property type="protein sequence ID" value="GIY28674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14240" checksum="7941FD507E7A7BFA" modified="2024-11-27" version="1">MSFPVKFALTRSSDAEHENQRQGAKESLHCTQVGSGYLRLLSKENIKDERDSNRKTRAVRRVRPTNFQKDASGGSGLKKSRRARPLAIGRALQVGGSRHLAITHAGAFPTSLQVPSRKGRIFIHICNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFW5</accession>
    <name>A0AAV4SFW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_93671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009565">
        <property type="protein sequence ID" value="GIY32899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9911" checksum="05E451A84D4DD9AF" modified="2024-11-27" version="1">MSRATRCRRTLSSELPLLRGRVPEDLLQPVLPVRASTAGPLRHRLLLRQGAQSHLRDTRLQRVRPVFPSQYHFSSSLCFAYPYPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHI6</accession>
    <name>A0AAV4SHI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_367541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009506">
        <property type="protein sequence ID" value="GIY32424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13777" checksum="5C899FB31A8248B3" modified="2024-11-27" version="1">MDNLLKSEEEFTNNAAGFNPNFQGSDSDDKHCENNPRCLRNGDFKETFKYQDFDKRVSQRHFIGNDPFNNEDIKDLSPHDHQKVLNVMQNMVFYFSSKYPEDFDESKNPEIKVFWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKH6</accession>
    <name>A0AAV4SKH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_518111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009713">
        <property type="protein sequence ID" value="GIY34012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="12733" checksum="027F1D1CD3DE90BB" modified="2024-11-27" version="1">MAVSHPSVDPINLWDQMTFKARAAGGVGVDALPWQIPNSLKNEVADVRKEKEKVDDSARPSSGSLNYDIQIYKPVGPMGPYKSVGPMGPYKSVGSNVFKARGAGVGGCRGPPLGIHSKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNN4</accession>
    <name>A0AAV4SNN4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_435191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009722">
        <property type="protein sequence ID" value="GIY34085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="15170" checksum="C88C8C4B081BE49B" modified="2024-11-27" version="1">MDLIQAKSVLCRLLSCNIDEMDLVDLKILVRRRKLLWHPDKNTDKNSPNEYSAIYTEAEPDLFCSESQPDLFCSESTLPPSPGPSNVSDPLEDALLPNRTRFLFLDHNLIREPPFFLLESLEFLTNNAWTCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SW15</accession>
    <name>A0AAV4SW15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_551531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010173">
        <property type="protein sequence ID" value="GIY37456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SW15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12369" checksum="79BF12805FC9CDA6" modified="2024-11-27" version="1">MDRKRQVWYLFVLSQSCELLKSSDLTFLLVVENGSKSSQIESIHPQKQFGLKSVRCRIDTIAVSINLCSQNSRLFNAAFSVWIGVSGSPKPKEDFIQFRYPNLKRKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWM6</accession>
    <name>A0AAV4SWM6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_89121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010268">
        <property type="protein sequence ID" value="GIY38170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043573736" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10976" checksum="A304BB598853AC5F" modified="2024-11-27" version="1">MRTLHLMLMYLVFKAIWSWKSTFVYSRNFSGTSETTSSRECPRDHSVLRAQLSGEGLKIVLIRSEGPRELTRQGMPHSNSLWMDEKQKDVRVMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0M4</accession>
    <name>A0AAV4T0M4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_438371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010296">
        <property type="protein sequence ID" value="GIY38387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10884" checksum="47ADAE09E3207659" modified="2024-11-27" version="1">MPGCKISCLEKHQLISRRPNSPVGLLPMKGSELQDVLEGPDDPSHFSGIARLNCLLHDVIKMGAATWNYHQTWLIENTRSPIRPRFHIVSFSICFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5S9</accession>
    <name>A0AAV4T5S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010628">
        <property type="protein sequence ID" value="GIY40554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="18051" checksum="2E90A08E9C4EC688" modified="2024-11-27" version="1">MVNKTSRSDSNRALFLLLFYKLSTKLIDIFIDNKEKRRCLTMVTWCLPQAILHRDLGFTGLLSKVPEFGPWDSRAILQMLYISSCSKKWTHYEDLPLVREGFSISFKFIEIMVAAELLKVLFVLITNRKAEPFPFEVPIHEYVFISKLFQNLPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TAK2</accession>
    <name>A0AAV4TAK2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cadherin Y-type LIR-motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_489531</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Cadherins are calcium-dependent cell adhesion proteins.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011009">
        <property type="protein sequence ID" value="GIY43688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TAK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.900.10">
        <property type="entry name" value="TCF3-CBD (Catenin binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000233">
        <property type="entry name" value="Cadherin_Y-type_LIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027397">
        <property type="entry name" value="Catenin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01049">
        <property type="entry name" value="CADH_Y-type_LIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin Y-type LIR-motif" evidence="5">
        <location>
            <begin position="114"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="67"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY43688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="23962" checksum="832C2392D7DD179F" modified="2024-11-27" version="1">MRAHSRAFASSTVLNKSRFRNKRRGVDASGGTIPQFVRIERCSTTTRRGGGRRRHEERLRHHPLRIPIDATGTPLGAKPGPEKPPIKEPRQRHIPRVTAAWASSSRPPGQRPRPNAPPFDDLRNYAYEGCGSTAGSLSPPGLDRRRGQRPNFDYLNGWGPRFPEAGRHVRRGQRGGGLKGNSSLWSLPTTSFRKKKIFEDGVSKYIPLITCVSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDR8</accession>
    <name>A0AAV4TDR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_431101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010805">
        <property type="protein sequence ID" value="GIY42123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8724" checksum="977424A1B1380C10" modified="2024-11-27" version="1">MYVYPFQILIYRVKSSVQFCKKSFHCIPQNGNLIPGMVSFACDNFKVISVGICFKTSLKNCNGLVIMEAMQIDSARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGT7</accession>
    <name>A0AAV4TGT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNase H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">R1A1-elementORF2_87</name>
        <name evidence="9" type="ORF">CEXT_65951</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011174">
        <property type="protein sequence ID" value="GIY44661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY44661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20377" checksum="3219830FCD03FCE1" modified="2024-11-27" version="1">MNERNSKAVDFSIPYLVEESTFITPRPVNIKSNFTFLQVFDATTWFCLCAVLIVMSILFAKFKDSVGYNLFKLLGTIIGQSSNIGNSSLSSRILLTAFLLFTTVISFSYSGTLLSYLIQPTKVAPIRTFHELSRAVQSGDHKLYTIEFYVRELLASEEDHLKALGRMVVRKNWVVQKLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TP01</accession>
    <name>A0AAV4TP01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_24961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011299">
        <property type="protein sequence ID" value="GIY45663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TP01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17562" checksum="49E0BFEF204DAD43" modified="2024-11-27" version="1">MSNKFKVRDENFLKITYERLPGQYTTRWFEFEFQEYEPDLSSVLGYLHEDTNTWEFSLICETPEEPDFSDSASFEEMEARRAHIVEFNVIKKSRDSQSSNGDATPYQCRRSKQILMNGYILFSFPVEEFLSYLTSSTSPPKEFEIPLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TPJ5</accession>
    <name>A0AAV4TPJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lipopolysaccharide-induced tumor necrosis factor-alpha factor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">X975_09043</name>
        <name evidence="10" type="ORF">CEXT_174941</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Lysosome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CDIP1/LITAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011462">
        <property type="protein sequence ID" value="GIY46677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TPJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037519">
        <property type="entry name" value="LITAF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292:SF6">
        <property type="entry name" value="FI16602P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292">
        <property type="entry name" value="LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="9">
        <location>
            <begin position="16"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY46677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="10630" checksum="63122037473EF2B4" modified="2024-11-27" version="1">MAITCSAGFISDGGDFHTVVITPPVMLSNQPMSITCGNCRRTVMTTTVKENGACAYIATIFVCLLCCPCFWIPLCLDSCKDVHHSCPGCGARLGTYKKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRJ9</accession>
    <name>A0AAV4TRJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_267861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011469">
        <property type="protein sequence ID" value="GIY46698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10914" checksum="374B822EE9B8F86D" modified="2024-11-27" version="1">MRHSTIPCQQIFHLRAEIQAPRKQGEIKGLPQRDINDWGAQTGGGRPILLISGRVIERDDEKAAPSLLMIGVNLTLSSSATGLNVPPRNISSWDQSGVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVJ9</accession>
    <name>A0AAV4TVJ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alpha-mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MAN2A1</name>
        <name evidence="12" type="ORF">CEXT_518691</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + 2 H2O = 2 alpha-D-mannopyranose + an N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:56052"/>
            <dbReference type="Rhea" id="RHEA-COMP:14368"/>
            <dbReference type="Rhea" id="RHEA-COMP:14369"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28729"/>
            <dbReference type="ChEBI" id="CHEBI:60615"/>
            <dbReference type="ChEBI" id="CHEBI:60625"/>
            <dbReference type="EC" id="3.2.1.114"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="BPLR01011972">
        <property type="protein sequence ID" value="GIY50393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004572">
        <property type="term" value="F:mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.50:FF:000001">
        <property type="entry name" value="Alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.110.10:FF:000007">
        <property type="entry name" value="Alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="entry name" value="Glycoside hydrolase family 38, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050843">
        <property type="entry name" value="Glycosyl_Hydrlase_38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11607:SF70">
        <property type="entry name" value="ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="Families 57/38 glycoside transferase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 38 central" evidence="11">
        <location>
            <begin position="470"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00059516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00093232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY50393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1119" mass="127950" checksum="A1B1A8463CB45E38" modified="2024-11-27" version="1">MPKLILLRVFQKPRTKYLISIVILAFVSIAILYHTIGNKQNPTPASHTDSVRNSEISLQVVEQIDAEVEIVKVKSRQKLPCDPLPPLKNVDLNTPDVYPLLNFKPPYRSYWNYTFEKRYLKVRENWNKLPLQVIIVPHSHNDPGWLKTFDGYFMAYTAHILNNMADKLAKYKDMTFVWSEISFFSRWWNSLKNRPHLRDQVRQFLRKGQLEILTGGWVMTDEAAAHIYGMVDQLIEGHQWMKTNLGITPRSAWSVDSFGHSSTVAYMLRATGMRNMVIQRTHYAWKAYLAEKRQLNFFWRQEFDNLSPSNHSSDIMCQMMPFDLYSIKHSCGPDPDVCLQFDFRRIPGEYSESRASPVTPEKVAEMSDLLLGQYGRIGSLFPHNVVLIPLGDDFRYNHDTEWDQQYENYAKIMEYINSRSDWNANVRFGTLRDYFNLVHKRMHSIGYENIPSLTGDFHTYGDIYGEGHPSYWSGYFTTRPYWKHMCRDLQHWLRGAEILFSFSRAFAAQHNLLHLLRRLDQDYAYLTLARDSLGLFQHHDAITGTSKEAVTADYGMRLFRGIKETKGIIAHAVLYVMAEEAVKRSVDLRPAHPLTSYLYPDIDQSQYDKLPEKVPLSIPSQGRKVVIFNSKARRVSEPVRLRVGNAFVKVLGPDGEEIPIQINPAWNGSVAVLGDVYELLFIAELSPLSLTTFTVISTDRVSRPRSQVAITLNDAFAKQPHNSIFSFQSPSDVDIELATPLINARFSKQSGLLQSIELKDYNVINKVALVLQAYRSEEFRSGAYLFHPLTNDPVQNISGRFPIIRIVKGPICSEVTAVYSNVVMVTQRVYHSSSPLGNGVELEVTSDIAQLFDVNLELFMRVKSDIKSGNSFYTDANGFQMIKRNTLSYLPLEANYYPATSAIFLEDEQSRLTVLMSQAHGVASLSSGWMEVMLDRRLRGDDNRGLGEGVMDNKRTMAQFWLLLEAVKEDSTEEVPTLSLNSHILSSLIAHPPIVVATHSFEQRNLKSKVEFLESSFPCNVELFNLRTMPAHDDFDVPSNSSLLIVHHKGVSCRVKSWDETSCTTHKENSIRLDFKTVQLSSVHKTSLTGIMSEGKVWNSTVVHLSPMELTSFNVTFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWJ3</accession>
    <name>A0AAV4TWJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1758 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_239050_1</name>
        <name evidence="2" type="ORF">CEXT_195701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011822">
        <property type="protein sequence ID" value="GIY49340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349254" evidence="1">
        <location>
            <begin position="23"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="368" mass="42114" checksum="5C0C745752E15F7A" modified="2024-11-27" version="1">MSTPSCMREVLLMTLMVEVVSGNMRKRVRCLLDCASRRSYILRSTAEALHLKSLSSEKLTHSLFGGARTESKNHKRYSMRLRPVGRSTGYQFDFLDLDIICGVIPRSDIYGQILTGEVIQLNEGLTAINTKLGWTLCGEPKELNVQSLEGAQSMLITNLHVQNRKVSDMWDLERIGITDEVQTFSTAVEDQLVQEQFLKGLSRYEDGRYCIGISREDQHYLKFLWWENNKIVEFRHKRVVFGVTSSPYLLAAVISFHLKNVHTKFEVVAEKLLHAFHVDNCVTSVDTKVELEVFIQQSTAIMADAKMELRMWTFGPEQELSLQNVEPISPVLGLKWDRIEDSLFIPFKSEPLSNLSKKKTTIDSTFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4B5</accession>
    <name>A0AAV4U4B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_71319_1</name>
        <name evidence="1" type="ORF">CEXT_357531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012257">
        <property type="protein sequence ID" value="GIY52586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17746" checksum="2C83038C562E8CDD" modified="2024-11-27" version="1">MDIKYKESGLLVLVRCLISSNKCAYQINNAEITGFTAVEEYIDDSICQVQTEEFIQEKELNTHILKEELWEVQKTIHEKELNILKSGPQYIEVPYKQKYDLKMGNTVPTSIDLGHLRHWKIFPLSHQRLSPTRFIENFTIHTSLQSEPIPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8V5</accession>
    <name>A0AAV4U8V5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_753271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012481">
        <property type="protein sequence ID" value="GIY54201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="17596" checksum="574F3BF587EDFAB0" modified="2024-11-27" version="1">MCLDRKLKNKLLQGEKGTTGVGALFWGLSHKTGLVFSHKEDLNQKTGRKRKTHYVQMGALLNCFSGQALLKESRSNLFRYSEQRHRRNLVSFLFYFWFLVLFLVSSLSGLLSLMRKSLREKKHCCMRESRLICFFIVLLDIQMTEKSHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UC50</accession>
    <name>A0AAV4UC50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_597871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012631">
        <property type="protein sequence ID" value="GIY55327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UC50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16755" checksum="2857705293F87BA9" modified="2024-11-27" version="1">MPRVDKKKKTKIRTAKKNTTVQFILSTFFYGQMDNRRALWPLVPQTSDSNPGGGMDDYQKKTETSCIKPKNRSSPQPVCRTETSHPAKRVVLCHQMSDVIYDKLEKLSIVSIVHCNNTFKRCPIQRVKQSSCVAVFNGKWKSDDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCN3</accession>
    <name>A0AAV4UCN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_806581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012642">
        <property type="protein sequence ID" value="GIY55459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11471" checksum="648C3D313879CCF8" modified="2024-11-27" version="1">MKILKQPYFSTKSLVKLSLKKKKHFQLLQSIPQRNPFVEVSLRRENRDRKDTHFLHLSRNRSNKTSLSISPSRQPLLRNTPPRTQTPCVQKKKGGANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UF18</accession>
    <name>A0AAV4UF18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_22199_1</name>
        <name evidence="2" type="ORF">CEXT_203991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012756">
        <property type="protein sequence ID" value="GIY56315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UF18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY56315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="22971" checksum="ED894E41B82A636A" modified="2024-11-27" version="1">MWRKVEEEHCAVIEDGVFKSEGSTDVQMQVLKVTNAEVECNINSINRIGLHTQKHLGVDDSGICKNQNNVECDFNFLCMDQMSSQCNIPNTNIDLDTLPSSLSNVSPDSGIQSSGDSPLRIECELPPPPQNSTIDNQTSTSLMPSDYYNRTELSDASRKHDTHTKHVSPTPSPPILTPHEPLWTNNENQLCTEKRKVLMNILHHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNS8</accession>
    <name>A0AAV4UNS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_373311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013199">
        <property type="protein sequence ID" value="GIY59375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY59375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11913" checksum="45F2C496C3959737" modified="2024-11-27" version="1">MLNHLKLITPTLLKTNTTAPNIEEIVNQRVESIVQNIMIKMEQQTTLLIEIFQKTIENLVQYLVSVFHQTDLKKSPNRKRQMINLVPPTNNPMQWDAGGSNASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPP6</accession>
    <name>A0AAV4UPP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_633791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013201">
        <property type="protein sequence ID" value="GIY59400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12869" checksum="9E41BDD553E153FB" modified="2024-11-27" version="1">MVFLQRVFDLWVDLEIDEGNIQRFLKPQNPLNHIEITTNLNLAQPTPESQSPRESLKILALEAIHTIYPELDWSHIYTNKYVTRTNYSMTEQSSVVGSGIYSFIFLFMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4US32</accession>
    <name>A0AAV4US32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_267511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013368">
        <property type="protein sequence ID" value="GIY60715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4US32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13679" checksum="63BE10531EC0303B" modified="2024-11-27" version="1" fragment="single">ELALCVSEREGGSCQLHSYHSWKKCSFFFFIGTNSPMVDQDHADHAIPMVDLLADFETGKERFGGIALHLAVVLLGGMFSKTNGTGRSLYEKLNQLTPGPIQSIERECFYWLLLEQKEPANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVC2</accession>
    <name>A0AAV4UVC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_265261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013456">
        <property type="protein sequence ID" value="GIY61350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18862" checksum="BA6FA65AE4544A68" modified="2024-11-27" version="1">MIYIQYLKNFKIQSILLGEPNNTFSTEVSETFNANNNEIKFEETSDTQFQNAGEHTLILPDHSYIFYPSMVNNLGFQNDFVYSDSVVKNYTDVRDQKTTNFKGYDLIPNADFIDFYPYKDVENGIQFSVEENKLPSDEFFVLNDDNSTPLGNGQENEYIHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYK4</accession>
    <name>A0AAV4UYK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_365561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013654">
        <property type="protein sequence ID" value="GIY62703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12410" checksum="9CE0EE6662500306" modified="2024-11-27" version="1">MFLLEKNDTSLIVKRIVDIVYKNPKPHELLRKYHKSHYHLMSEECFVQNFPISPGGTFPPANSSRQESLTMVKGIRFPFGRKLSNRFIDTACLPCNSKVNTQPNSASGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYW9</accession>
    <name>A0AAV4UYW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_123701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013668">
        <property type="protein sequence ID" value="GIY62808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14886" checksum="D5D49899C3F11D9D" modified="2024-11-27" version="1">MLTDNRIQISPVSMEHSVKDSSLPFLYSILLLLSRKVEEWEARIWHSKLRFSNCVSDNHYHLIVPKLHTIDSMDCEAIHTFLAFGEMAPVIPCDQRPHKSSVLRFFIVTGENNKEFGLNWEKIYHPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V038</accession>
    <name>A0AAV4V038_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_403601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013699">
        <property type="protein sequence ID" value="GIY63049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V038"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY63049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="257" mass="29324" checksum="81D64E687E9A1218" modified="2024-11-27" version="1">MIEAPEPKLPPIMVRYTENLKDQIAEISNQFEDDVSIKTCWPPVSYSTEEIATELAELGLKLVDFDLFDVGNQFKDHFPAICIFGMDKEDIKRPQNEVPIEILPFLKQRPELTIFERKPAAVSTPTSTASSASAPPPPPPPATRGSMYHCEFCPYETNVVNHFQSHLDNHKSINAQPCNICNKVFKTPSKLQAHMITHQNIRQHTCVYCEKKFKTPATLKAHMKTHFNFEQLRCTFCDKTFSNETQLKKTLNVLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTN6</accession>
    <name>A0AAV4VTN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">D-aspartate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Ddo</name>
        <name evidence="8" type="ORF">CEXT_587461</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015129">
        <property type="protein sequence ID" value="GIY73821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF11">
        <property type="entry name" value="D-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY73821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18331" checksum="D68E4D0734F81B00" modified="2024-11-27" version="1">MVLKVAVIGGGVIGITSAYVIAENLEDVQVTVFSESWSPDTTGDGSAGYWCPYLLGDVPEEVLRFFWCQKSFEVFQGICKTEEAVEWGVGLLSVFSLATEPLKPLYQDLFLEYRPLCAKELSMFLADADYKRKGGKLIEKKIETLHELSGEYDVVINCSGLELDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZX8</accession>
    <name>A0AAV4VZX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_485601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015323">
        <property type="protein sequence ID" value="GIY75301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9057" checksum="54706080D7FFC76C" modified="2024-11-27" version="1">MMDSWSPTNPTFSSYPNQFSFRNFSSSSFPVVWAFSVLQESRLYAQPKVIRELSLVRCLSGRLRAPDHNPIRHPLRAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WH66</accession>
    <name>A0AAV4WH66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_128521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016086">
        <property type="protein sequence ID" value="GIY81139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WH66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14422" checksum="EAA247822A4F371F" modified="2024-11-27" version="1">MLKPFYRRPNGEKTEKFPPGHQCKSLTHGILVNYGNSTDCGNRRFKNRSLLYFICKSIRDLPKILEIVPDKHPFPQKAYKRKEVTDTRGKKGSANNVCSTRQPIKPQRTTSENTRKFQPGSTIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WI53</accession>
    <name>A0AAV4WI53_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein dachsous</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ds</name>
        <name evidence="10" type="ORF">CEXT_66351</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016134">
        <property type="protein sequence ID" value="GIY81484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WI53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005911">
        <property type="term" value="C:cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060429">
        <property type="term" value="P:epithelium development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000020">
        <property type="entry name" value="Dachsous cadherin-related 1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000134">
        <property type="entry name" value="protocadherin Fat 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000275">
        <property type="entry name" value="Si:dkey-30k22.7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050971">
        <property type="entry name" value="Cadherin-domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24025">
        <property type="entry name" value="DESMOGLEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24025:SF28">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="117"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="297"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="401"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="509"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY81484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="671" mass="74600" checksum="60EB0A80497908C9" modified="2024-11-27" version="1">MALHHVQLHGINGGGHYMMVEDHVSATDPDCGVNAMVNYTFPKGIVSLLDFTLQQVSGDLCIARPLDHETRSSYEIPVLATDRGEFLLFYAGQTNLFSWPEHDCRGEGASAGRERQSARLLPPRVQRESARGEIVSSAVVVIVATDEDSGRFGEVTYEIIAGNDLGLFQIDHRTGEIFVLRSLSTDHPLHHLVISVKDGGGLTATAKAHVYISVISSDQQPPVFQKARYTFFVQGMLHHRAGPVRYVIYSGDPEGFFTIDPLSGTIKTKGRLDHETHPFLLLNIQATVEDRPYMGILSNSLKISVPENADLRTPIYVVHAEDLDSNRNGEVQYILLDNPDNMFVVGEKSGSIMLQHLLDYELRRHYILILSAVDSGSPQLSSNVTLMVEVQDVNDNAPAFEKSEYKVNVLESLSVNSQFLQVTATDMDTGNNARLTYKMIANAEDPVSSKFGIFPNSGFLYLKETLDREAVDTYSLTVSASDNGSPSLSSTAVVLVQVLDANDNDPEFVEEAFVFSVQENLEQGQHVGTVSAIDRDLGNNASLRYSLLNSNGSFQINPVTGEIFTQTTLDRESRPRYELTAEVRDQGTPHRSDRALVNVEVIDRNDNPLCSWNRLSLWWRFSKNSLSAPRWCRWLQKMLTRTKMGPSSMKSCKVRKTPMEQMLLALTPAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WM47</accession>
    <name>A0AAV4WM47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fat-like cadherin-related tumor suppressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">kug_7</name>
        <name evidence="8" type="ORF">CEXT_676761</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016423">
        <property type="protein sequence ID" value="GIY83757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WM47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005112">
        <property type="term" value="F:Notch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000125">
        <property type="entry name" value="Neurogenic locus notch protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000095">
        <property type="entry name" value="Notch, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12916">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12916:SF10">
        <property type="entry name" value="NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 2 PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="49"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY83757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="348" mass="38259" checksum="F829D583714EF686" modified="2024-11-27" version="1" fragment="single">LARFLGSRCEIDTNPCASNPCLNGATCHNVNNTFRCDCLEGLSGKRCGYGRYCNPNPCHNGGVCEEGTYGPLCKCKGFYGDICQYDVNECQANPCANGATCHNVPGSFHCQCPLNVTGSLCSELLYTNSITSTRWNTTVEEIIGITVVVIFIMLLAVILACCWRIRHKRRQRRPSLELNDEPGPNEFMLKNPIIEKDNVKRVSKISNLDATFTTPPLPPRPASYTPSTQESLSVLAKFDTVRSYGSAAEDLEDNSLRYGGQLFQNISTHKSSHVSVPPSLTPPPPSSSDSDSLLKAGWETDLNSSKEKIYEDKIQNNLNPVVVNLPEEIDKHQKLTSVTPYDSVVDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WV87</accession>
    <name>A0AAV4WV87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_327991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016669">
        <property type="protein sequence ID" value="GIY85590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WV87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16210" checksum="84471D98497498BE" modified="2024-11-27" version="1">MNVKLTIYIALSKQSRLNNFLPFLAFTLAHPGTNQNHPPTLGRSKASNSFLPPCQEHLRNSEFFRFLFRINKFPLSWELGLTRHSLLRINARGWGRAGWTLWVGRVFWRRLALDLNHLLSKPSICPVSSIFFTVHPPSSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WX36</accession>
    <name>A0AAV4WX36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_100151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016740">
        <property type="protein sequence ID" value="GIY86088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WX36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9568" checksum="ED61EC96417B9296" modified="2024-11-27" version="1">MTVATEPKLPPIMVRYKDELKEQIAEISNQHKDDIRIKFAGEQLKIFPANSDVHRAIARYLTDQQLEYYVITPKNQRPAQSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1U5</accession>
    <name>A0AAV4X1U5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3',5'-cyclic-GMP phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Pde11</name>
        <name evidence="7" type="ORF">CEXT_338241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.35" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01016999">
        <property type="protein sequence ID" value="GIY87960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047555">
        <property type="term" value="F:3',5'-cyclic-GMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000032">
        <property type="entry name" value="Phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="6">
        <location>
            <begin position="326"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="6">
        <location>
            <begin position="466"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY87960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="573" mass="66954" checksum="C0783E8E1BC73035" modified="2024-11-27" version="1">MYSPVFLEIEKVESWLDDHPHYVHDYFVRKATWQMVDSWLLFHSAPQMTTVPQFFQLVSQVPLPPIIRLIPQFQCRTNARKRRNLYSLRTGIMSHVAEHRESLNIPDYYKIRDIGIRNAELYESSKLENKRNQVLLDLARMVFEEQSTIEQIVHKIMIHILSFLQVERCQVLLLDENTKAFSRIFDLDINDMKTENVDSSTSFEGRFPINIGITGYVATTRETLNIPDVLQDDRFDPSVDEDSNFCYHSILCMPIRNASRNIVGVSQLINKLSGTPFTKKDEHIFEVFVTLCGLGIQHAQLYERAMKAVAKTKVILEVLSYHATASLEEVRELLREYHISSTQTYNLQDLKFDDFSLNDKEMLKASLRMFMDLGFIQRFRIEYDVNFKNPNFSSKQVLCRWLLSVRKNYRPVIYHNWRHAFNVAQMMFAILRGTQILSHLSSQEYMNVVHFLKSAILATDLTVYYKAMLMTACDIAGITKPWKVQRKIAVLISNEFFEQGDVEKQLKMEPTDMMNRDKKDMLPLMQVAFIDSICLPLYEGFAMISDKLGPLLKGVKENRAQWLKLAEEKRTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3J9</accession>
    <name>A0AAV4X3J9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_758731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017252">
        <property type="protein sequence ID" value="GIY89752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3J9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14085" checksum="17A25CF10FFE56F6" modified="2024-11-27" version="1">METVQQLAIEERKRNNINNSRREKMVHMTFGIENAAAINISRTEAPKKSSEQGGVRDLSSPEGGRYSKYSDTWKHPVSLSSEVRLDLERAVIVTICYETKALVRNVVVEPQLLLLIFLLNFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4Z2</accession>
    <name>A0AAV4X4Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_421901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017146">
        <property type="protein sequence ID" value="GIY89055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10165" checksum="1F8128C9EF8564F5" modified="2024-11-27" version="1">MFFSGTEMDAITNSNSLCIQTYEAGLRVGRADERNILRNLPDERTPILKNRIMGFQSGKSRSLIRCRGFQNLDKLYKFGKQKICFKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X6D9</accession>
    <name>A0AAV4X6D9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_342081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017201">
        <property type="protein sequence ID" value="GIY89399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X6D9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="22013" checksum="FF8B490786345118" modified="2024-11-27" version="1">MPAIGVACGTEIFMTAIGKHQYNLVPCVVIQQTKIRRQMKHSPLKEQYYSGIRVYARTNFKAHSINTGLIHFFLFHEVKITGTGSRNVRGTCLSETKQHFTELNQLSLGAHAYEVDTPTAEDSGSLPFLMCSYFVITRRCIPGISLAANCLFQVMLPNLSRQVLFKASRKEMLFSSSHPQSLFRTHEHRYEAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7Q7</accession>
    <name>A0AAV4X7Q7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_405621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017300">
        <property type="protein sequence ID" value="GIY90200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7Q7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY90200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7507" checksum="AF929BF7AA55C0BE" modified="2024-11-27" version="1">MSMLFGSMRKSRSTSSSHSLPSPARLSEGCNAQLDISFMKQLAKEAKFKLTSRARQSFPSLKAERRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIF0</accession>
    <name>A0AAV4XIF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000388">
        <property type="protein sequence ID" value="GIY94423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10856" checksum="C23330B8C8379684" modified="2024-11-27" version="1">MMYNSLISFLNAVQPRARWVNCNCNAAFRATNLFRSCTAFAMNPFLPFRGWAIALITFHFDISPGECRYWMSGLANRWAFPDLTKLKGFHVVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ01</accession>
    <name>A0AAV4XJ01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Symplekin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SYMPK</name>
        <name evidence="2" type="ORF">CEXT_441281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017807">
        <property type="protein sequence ID" value="GIY94622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021850">
        <property type="entry name" value="Symplekin/Pta1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022075">
        <property type="entry name" value="Symplekin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245:SF20">
        <property type="entry name" value="SYMPLEKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245">
        <property type="entry name" value="SYMPLEKIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12295">
        <property type="entry name" value="Symplekin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Symplekin C-terminal" evidence="1">
        <location>
            <begin position="222"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="319" mass="36570" checksum="3D9503FA14755A71" modified="2024-11-27" version="1">MLKESVCCDPQMTESGFQLAEQMITRRPTQQLLFLGILTDLTLHENVEIRSKAANLVVEIHKTLKLDYAVEAFALKCLKFLLKASPSHSDFVYFSQPDLVWSEELVKLCLHLYLSLLPLNHQLIHDLGTVYVETSADIKRTILRALEAPVKGMSMASPELLLFVEKCPKGAETLVTRIIHILTDKHHLQLNLLTVFEIYTENEYLMFSKQYFTTPYCKRSLETKKIWEGFIKCCQRTKSGSSEILLQLPAPQLKEVLDSCPDIREPLCKYVDTLTDHQKAHIPEDITILLKDELKCLKLLPLSKIDDSKDENGFYSRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLZ3</accession>
    <name>A0AAV4XLZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_84961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017991">
        <property type="protein sequence ID" value="GIY95996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7749" checksum="88EFAB4D8F7DB8D8" modified="2024-11-27" version="1">MLSIQCQPVSHSRLSDYLGDTEGLKLLMVGYVVQNEDIFTIPKESNLVLTDARKGSLTNGFSVMGTPTVMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRM7</accession>
    <name>A0AAV4XRM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_313301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018067">
        <property type="protein sequence ID" value="GIY96616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16387" checksum="C2B122CE07DBAD1A" modified="2024-11-27" version="1">MSLSPANESFYRPEKNTDQQRNLDLSSKKNCNQLQFFLSADTENLRLRHPNFLEAVPFITCLTKSFFPEMSLSPANESFTFQKKNTDQQRKGRKQFACTTSQFFKSSTIRNLAKKEFFSEMSLSQLTSLLPSRKEHRSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XV25</accession>
    <name>A0AAV4XV25_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Myosin light chain kinase, smooth muscle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Mylk</name>
        <name evidence="11" type="ORF">CEXT_236891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000804">
        <property type="protein sequence ID" value="GIY97593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XV25"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342:SF20">
        <property type="entry name" value="MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00014">
        <property type="entry name" value="FNTYPEIII"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="10">
        <location>
            <begin position="69"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="192"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="450"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="450"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY97593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="496" mass="55457" checksum="C564841AB5EFD00C" modified="2024-11-27" version="1">MLFLKRLGGRVLSDEGGRLSILDGREMSVVTVNDVTADDSGKYVVSVENQGGGDSCFASVAVVGFPEPPGGEPTASEVTDHSLVLSWYGSMYDGGSVVTGYQVEMCTLPDKKWHKVASSVNTSCSVPGLSKGQRYIFRVRAENRYGSSHPSKESKIIRLDDFLQDDSSADEEPKELSAPITIESGTNFTERFDLKEEVGKGRFGTVYRCVERACSRPRAAKVIRCLKVKDKEKVRQEIEIMSRLQHPKLMQVLAAFESGRNMIMVMEYISGGELFERVIADDFVLTEQDCILFMRQICDGVAYMHRNDVLHLDLKPENILCKTRTSHKIKIIDFRAGAHLQEGREPAHPVRHPRIRGPGGHQLRARLSRQRHVERRGHLLCPIVSLLVKNVRNRLSSEQCLKHPWLATAGLSQKRPLSTEKLKRFIIRRKWQKSGTAIRALGRMVSLSRSSLGSSCDSYSPLGSPTSSRSRSRSSIMSRSETTESGESDVFQDLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y278</accession>
    <name>A0AAV4Y278_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aromatic-L-amino-acid decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">DOPA decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Ddc</name>
        <name evidence="11" type="ORF">CEXT_705841</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.28" evidence="7"/>
    <dbReference type="EMBL" id="BPLR01018555">
        <property type="protein sequence ID" value="GIZ00536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y278"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004058">
        <property type="term" value="F:aromatic-L-amino-acid decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042423">
        <property type="term" value="P:catecholamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042427">
        <property type="term" value="P:serotonin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1340.10:FF:000001">
        <property type="entry name" value="Histidine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF167">
        <property type="entry name" value="AROMATIC-L-AMINO-ACID DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0127">Catecholamine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIZ00536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="256" mass="28060" checksum="78B11C6FDD429D03" modified="2024-11-27" version="1">MDSEEFRKCGKELVDFIADYHETMRERPVLPDVQPGYMRGLLPDHAPENPEPWQDVVADIEKVIMPGMTHWNSPHFHAYFPTGSSYPAICADILGSALTCIGFTWKASPACTEMEMMMMDWLGKALQLPEHFLFESNGSGGGVIQGTASEATLVALLAARTRTLKLNKGSKLGDLVSYASDQSHSSVERAALLGAVEMKLLPSDDNLSLRGEALEKAIKEDREKGKKIPFLVVATLGTTNTCAFDNLVEIGQICEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y491</accession>
    <name>A0AAV4Y491_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_374221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001269">
        <property type="protein sequence ID" value="GIZ01241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y491"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9863" checksum="06A81AAEAC3341B7" modified="2024-11-27" version="1">MPVSRKGWRQGPKGSLNKQIDREGVAKKRSVPIGLRGGDEDRRGPRRALRYGGEKRKQSLLGMKRDVEDYWSSLTPRVAEKQRQCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4A4</accession>
    <name>A0AAV4Y4A4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_460281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001234">
        <property type="protein sequence ID" value="GIZ00982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4A4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9286" checksum="21F89AF6D4919EB8" modified="2024-11-27" version="1">MPETEIPRSLNLTVSHCISADHCSGGLAELNENAHVSESGLSPGGMLVCSVRTGIPLISPGGAGFRISGRYQRRMTRAVLLEPQLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5C5</accession>
    <name>A0AAV4Y5C5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Svep1_18</name>
        <name evidence="4" type="ORF">CEXT_574921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018824">
        <property type="protein sequence ID" value="GIZ02552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5C5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="Sushi" evidence="3">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ02552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19307" checksum="216872A376852720" modified="2024-11-27" version="1">MMKTNCWYKLAGQECLIKCKDDDSTISITCQNDIKWGPLPNIECPIRINKKSPTLCPTPEISETFEYTEDCASTSVEGKCSVKCRHGGMLIGNNYIKCTRYGKWSSLPDCTCSIPIFSNDLKAKKKIAILSNEEANVTLNVKKICNWLEKTSFPVRIIQNGVLNQNASKLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y773</accession>
    <name>A0AAV4Y773_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_149619_1</name>
        <name evidence="8" type="ORF">CEXT_140051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018754">
        <property type="protein sequence ID" value="GIZ02050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y773"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026218">
        <property type="entry name" value="HRG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16954">
        <property type="entry name" value="HRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIZ02050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12007" checksum="4DF808FCB4C5F008" modified="2024-11-27" version="1" fragment="single">MHLTRRMDKYHNSSTLEGIKIFSMIVSIASGISVGVFTILAFFNKQSFSLKGSNYYSSAVFSGICLATSIELYVMAQWYQNALRASALEARATELSSNSYSLRPTTSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAT1</accession>
    <name>A0AAV4YAT1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_71496_1</name>
        <name evidence="2" type="ORF">CEXT_395631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018933">
        <property type="protein sequence ID" value="GIZ03325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38338">
        <property type="entry name" value="AGAP013079-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38338:SF1">
        <property type="entry name" value="AGAP013079-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11555" checksum="272C22ADD5B47832" modified="2024-11-27" version="1">MAFMMPVVKNDYNIYPSCPSSRAGLGTPQSSRGSSLASSPSGAASFMSSPRHSQTPAYANMPKSQSQTSLHKFHNRLLEKLRKTFRSKDSSADDVNQSSSPGTVTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M7K3</accession>
    <name>A0AAV4M7K3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_125635_1</name>
        <name evidence="2" type="ORF">CEXT_112711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019430">
        <property type="protein sequence ID" value="GIX67752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M7K3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="358" mass="40235" checksum="02F2D10E2C68E6EE" modified="2024-11-27" version="1">MVSTYEMFSQAGRHQPTYGLSQNYTHQVYPQYDNINFNSCNTNIMENSNYTQNLQHGMAAPWYYTVSSNSQTRPPVMMEDWMGSLTTNASNLQGQGIVQFPDNTTTYHYPRSGVDVSPADYSLQNAGHMRVQVKGEQAVAIAETTDNQPPSSESVVAVSSDGMSGTDSPLTMNMHINQNGNAMFRPQPARSPYEWIRKTSYQQTQPNPVLSVCRQALCNNTTAFLSSSQKGKNSFKLCVPKFRSLFYKWFRFVSYKASINSRLFEVKSCGILQRLSTLSSRFQLSSTFDQLTAAFRKSIKITSPKINRSIFSCSSVKAHKCQAAHSSSPNKGLKVGHHKDIHLMFWDAAVCDNHLYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9L1</accession>
    <name>A0AAV4M9L1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ANK2_12</name>
        <name evidence="2" type="ORF">CEXT_196441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002017">
        <property type="protein sequence ID" value="GIX69112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9L1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="21085" checksum="4B125F84113A5D14" modified="2024-11-27" version="1">MVSKEKNLKSQFKSPQKTGGKVMEDANIVTETGNGKKQGKKEDDPSKSETKAKETGGKDDGNKNNNTIPRLTETSKSSSLDEGDVRLVIERKTHPGVSIKIKMKDNQMKGKHKTVDATDLSSTQGESDQSCVKDSGYISTSESVHKHQRSITIDFGHTTAKFNAGMKNSSSKYVGNVMSKERTFLPLSKSQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDY8</accession>
    <name>A0AAV4MDY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_524321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002157">
        <property type="protein sequence ID" value="GIX70642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13469" checksum="73650E983785B9A0" modified="2024-11-27" version="1">MRDSIETFCEMFAGVGVCPGDWVEEYTGYIVGNLNGRLRAEFACVDFNPDALQHHHQGGKGSTHLAFHDGKQPGVLCWFILALRCVFQMRILKMWVATCWTCIYYYLSGMTVLLFFCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEX3</accession>
    <name>A0AAV4MEX3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_469761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01002046">
        <property type="protein sequence ID" value="GIX69374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF55">
        <property type="entry name" value="RNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="2">
        <location>
            <begin position="57"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX69374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="28842" checksum="60F2AC6C0E37C1A5" modified="2024-11-27" version="1">MGQTFSQSLGFIRVPQEWTNVKNPDPDIEGGIKEYLKFDDLKSNEKKKLVVENIDAQNEMSDPSNPQSEKFEPYTFSDGIGRMSNELVEEVYKHFNVEDRKPSAMQIRYAGCKGMLVVDPELEGKTIRFRESMKKFDSDNNYLEILKFSEKRGCFLNRPFITILEQLGVKKEIFLKLQKEMIQKHISSMFHEGEAYNFLNRHALLRINFSNMFVANICFTEDPLFRSMIYALFQKQLELLKNKAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGH6</accession>
    <name>A0AAV4MGH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-gulonolactone oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Gulo</name>
        <name evidence="5" type="ORF">CEXT_97491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002148">
        <property type="protein sequence ID" value="GIX70541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF8">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="41"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX70541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="261" mass="28980" checksum="2ECCA23947970F5C" modified="2024-11-27" version="1" fragment="single">MSEADHLFRPSSLNIIYTSKSSNIMKSGISNVHFKNWAETFECVPELFFAPKSQEEIAQILELAREGNKKVKVVGCKHSPSDIACTSGFMISLQNFNQLIEIDKKLLRAKVQAGMKLTELNEILYSHNLCLSVLGSVSDITIGGAISVGTHGTGIEYGNLSSYVTEIELMLSNGTVLTLSPEKDFELFQAAVCSLGSFGIILTVTMQCEKAFNLQMRQYGLPLKEVIENLDVHLTGSDHFRFMWFPYTDNVVVSHATRTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNH4</accession>
    <name>A0AAV4MNH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arylsulfatase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Arsb</name>
        <name evidence="8" type="ORF">CEXT_409821</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020013">
        <property type="protein sequence ID" value="GIX73981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047115">
        <property type="entry name" value="ARSB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342:SF273">
        <property type="entry name" value="RE14504P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="7">
        <location>
            <begin position="79"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX73981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="296" mass="34231" checksum="513E80B72D0196E0" modified="2024-11-27" version="1">MYYNFRNKKPKTTWDKNPSTGNLDVRDGSYKFVGRKVFPLGTMRNITVSLITYKDEFSPSTFHTHGEIKLFERKETSQPHIIFIFADDLGWNDISLHGSPQIPTPNIDALALNGLILHNYYTWRLCTPSRGTFLTGKYPNRLGLQHSPIKVGESSGLPLYEVTLPQHLKKLGYRTHMIGKKMAFKWHLGYQTKEYTPTYRGFDTFFGFLNGFIDYYDHTVWEPTFLPNIPHYYGLDFHNGTTILKDKQGQYATHLFTEEAENIILNHDTSKPLFLYLSHLASHTGNDFKPVQAPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQA0</accession>
    <name>A0AAV4MQA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_300841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002523">
        <property type="protein sequence ID" value="GIX74722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14147" checksum="1FC3C8EA0906EF0E" modified="2024-11-27" version="1">MGASIAECISEKGMRYFYGMHYGGNQDVVDEPDDDDEKIYKCDSVMPPTSYVMEECMYDQPSSQEPSGQETTMVANDEPAQDYDEFDIDLSTPLVIVEDDLPVDIEQTTPSTLDENHKETIPSTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRJ6</accession>
    <name>A0AAV4MRJ6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_788981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002468">
        <property type="protein sequence ID" value="GIX74051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043775044" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX74051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="18282" checksum="8C90F82E23905BDA" modified="2024-11-27" version="1">MRFLLFFSILAVLFDVLPVQARCTPRIAAKPRKACHLRDPLIDISHQQADRHEKKHRRSSHFIWQQLFSSSLPFIYERLADALYVDLTDILSSNTSVTFIESTVMIAQSFCLLVKMNRGSFNMPSSSPYSAFPRLISVLNKIVTHCQFKLLFSDVIFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTE0</accession>
    <name>A0AAV4MTE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_269531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020090">
        <property type="protein sequence ID" value="GIX74712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11308" checksum="E9D4304C3919B29C" modified="2024-11-27" version="1">MHRGGFFGLATLIPHVREFDARTHFGSPSIQRNSPNMPAPIIPDFEHSKISKLIGAFLTIRTGSGGIGVGNKSQGSPVYERSASTSDGGCLRWVVMGWLLERIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZI0</accession>
    <name>A0AAV4MZI0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Golgi integral membrane protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_1392_1</name>
        <name evidence="4" type="ORF">CEXT_535331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020299">
        <property type="protein sequence ID" value="GIX77105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX77105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="60017" checksum="A29FF80C6E42A709" modified="2024-11-27" version="1">MGEQNSTPSSNPVFIVIMRNSRGKLFVYVAVLGVLCFIGFLLSNTHTSLKELEGINEKCQQQRDSLSAQLQANEKQVSEIENKFQIEKDEKEKLITQISQLKTSYTELEEDKAQSENALQTQLKHVQSQKEAETDKLKTHISELLSEKDKLETSNNAYVWKLEQHASELKLCHLQYEQVKSEFQTCQEQLKMHNMNTVDHFPPHAAFREKAVNIAPNGSPLPHQQKPLDLPPHPALFGGNPQAVQGTLGHLGKEDKDKINETASPPLLEKVSLLAKPHIMPGNLLGDGVLPKPGDLKPVFNNELDAAVEVSDFKKSVKPLLLGENMPNNIEDNHINNDKKTNLLLQPKDAENHPQVAPPNFENVEDKDDHAAERGEDGNQYANPDAKPQVEEPVLGRLNIPRKEPLPVPVQENNDIGVQMQQMNDMMNKSPGDVNNAAEQNVLGMPPNLGPQEQKHHEFKNGAAFLHRGADAHRVMDDKNYEEDDDDRENDDEPPNGLAPAMKGVNNILPDNDFDDQENQDNNDNAKEEEGVVVAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZS2</accession>
    <name>A0AAV4MZS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_313671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020372">
        <property type="protein sequence ID" value="GIX78009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16676" checksum="4A7C5D8077F8515E" modified="2024-11-27" version="1">MLKANFRHRGIEPGPPEVETRYLTTRHCGLLVSYSIKLSALTIQAVGLLETWFAYFGERRAWQRSFLERVTNDTYDHITCFIEEIASAGRQLAESGMMWQDLGSPAQPIDRACRHITKADHCFSFRINAVHGLSMLQNCTRITLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4L7</accession>
    <name>A0AAV4N4L7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Thymidine kinase</fullName>
            <ecNumber evidence="10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Tk1</name>
        <name evidence="12" type="ORF">CEXT_734481</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>thymidine + ATP = dTMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:19130"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer. Tetramerization from dimerization is induced by ATP and increases catalytic efficiency due to a high affinity for thymidine. Tetramerization is inhibited by phosphorylation at Ser-13. Interacts (via the KEN box) with FZR1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="10"/>
    <dbReference type="EMBL" id="BPLR01002856">
        <property type="protein sequence ID" value="GIX78626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4L7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046104">
        <property type="term" value="P:thymidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000761">
        <property type="entry name" value="Thymidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="THYMIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441:SF0">
        <property type="entry name" value="THYMIDINE KINASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="5 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX78626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="169" mass="18980" checksum="5FAB9175D18D7581" modified="2024-11-27" version="1">MLDFTSKISKIVCPSQAKGHVQVIFGPMFSGKTTELIRRLKKYQIANHKCLIIKYPHDTRYSEKEISTHDKQTLDAVSVGILSDLKNQTEHYSVIGIDEGQFFSDIVSFSEEMANNGKIVIVAALDGTYQRKGFSNILQLIPLAENVIKLTSVCMLCFGDASYTKKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6Z3</accession>
    <name>A0AAV4N6Z3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020568">
        <property type="protein sequence ID" value="GIX80070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6Z3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13033" checksum="302ED598EF947764" modified="2024-11-27" version="1">MTSIVSIFSFIDCISVLTSKFSQSASYRSHQIENLADTTHCYSRPNLGTYREARSTYPKKMHPNLLSFSADLEFCIEVSQIKSSKLAELDIRAFKQRLVFRGVDIFFFFDVVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ78</accession>
    <name>A0AAV4NQ78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_636531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021189">
        <property type="protein sequence ID" value="GIX86972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16426" checksum="4D158A623F55C253" modified="2024-11-27" version="1">MVTLGIDEILERAFVECNSEAVFNVWEASDTNYVTNKISDDLKLCIYSLSENEEVVVNILMIIKDLLENYELDLYQKSVLLKCMLEIITEECVCAVLNVNLLFNDSLVVEWLKNEASLEGSMLIFGRKIPFIGGKLYSLLMPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NS31</accession>
    <name>A0AAV4NS31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_273881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021138">
        <property type="protein sequence ID" value="GIX86399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NS31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10284" checksum="921D0A8D7D15DBC8" modified="2024-11-27" version="1">MRCGRQGGCAEAENNRASLAFELPRKELPRAHLSARAQAPFLIFLEVRAKGDGHISQTPLRASYSFFISYYAGKHLVVPAVAWTYFKFEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSK1</accession>
    <name>A0AAV4NSK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_415021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003703">
        <property type="protein sequence ID" value="GIX87673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11222" checksum="BDBE663A80DA47CF" modified="2024-11-27" version="1">MERKGRYDTTDAARQQQAHKNLSSAVSSCFRPSKSAHNVRTDAPSHGTVCLSLSMTVIASIRFIIFSGKYSNKTGAGLVRCCLLVTERKVVKKEQMWNSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSZ5</accession>
    <name>A0AAV4NSZ5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tyrosine-protein kinase</fullName>
            <ecNumber evidence="13">2.7.10.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">Src64B</name>
        <name evidence="18" type="ORF">CEXT_725321</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily. Tyr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="13"/>
    <dbReference type="EMBL" id="BPLR01003573">
        <property type="protein sequence ID" value="GIX86247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002009">
        <property type="term" value="P:morphogenesis of an epithelium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05034">
        <property type="entry name" value="PTKc_Src_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09933">
        <property type="entry name" value="SH2_Src_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11845">
        <property type="entry name" value="SH3_Src_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000399">
        <property type="entry name" value="Tyrosine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000036">
        <property type="entry name" value="Tyrosine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000001">
        <property type="entry name" value="Tyrosine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050198">
        <property type="entry name" value="Non-receptor_tyrosine_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24418">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="1 12" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043450305" description="Tyrosine-protein kinase" evidence="14">
        <location>
            <begin position="24"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="16">
        <location>
            <begin position="59"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="15">
        <location>
            <begin position="126"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="252"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIX86247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="528" mass="60173" checksum="EBBB8518E4DD7984" modified="2024-11-27" version="1">MSLSFSICPRILLQWVISVGVESGNGGINLLHERQRYPNCAPNTPIPTFSPDGIRQGNNCLKIVVALYPYNARDQGDLSFRKGDRLGILDDSDPDWWHACHLTNQQNGYVPRNYVAPEKTVESEDWFFGRVSRKEAEKMLMLPSNPRGAFLIRNCEQTTGIIKGAYSLSIKDWEHQKSDHVKHYKIKAMDNGGFYVTTRKTFATLQELVAYYSEGANGLCHKLTIPCPKPKPHLWDLSPDTRDEWEIPRSSLQLIRKLGSGNFGDVWYGTTEVAVKTLKSGTMAPSAFLQEATIMKKFRHEKLVSLFAVCSKEEPILIVTEYMVNGSLLDYLRNKEGKNLRLHALIDMAAQIASGMAYLEREQLIHRDLAARNILVGDNNIVKVADFGLARIIEDSEYTARQGRKVKFCNEFLGAKFPIKWTAPEAALLGRFSIKSDVWSYGILLYELITHGQVPYPGMHNREVIEQVERGYRMPKPTNCECPDSVYSMMLQCWDADPEKRPTFEFLFGFFDDYFVSTEPSYRNAEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYU1</accession>
    <name>A0AAV4NYU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_623451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021433">
        <property type="protein sequence ID" value="GIX89528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8999" checksum="208E18AB243A44E0" modified="2024-11-27" version="1">MEPKGYQINYKTSRSSPTTDSRVVFTHPRINPRRGVPSLIKCFLLRPKQKVQEAGFPRALSLHNEMAASFCSSLVHQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3Z2</accession>
    <name>A0AAV4P3Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_241591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004084">
        <property type="protein sequence ID" value="GIX91997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="241" mass="29098" checksum="730D4203A3FC8E0F" modified="2024-11-27" version="1">MNKAYRMHHIAYITMNKAYCMYQIAYITMNNAYRIHQIAYTTMNNAYCVYQITYITMNNAYRMYQIAYITMNNAYRMYQIAYITMNNAYRMYQIAYITMNNACRMYQIAYITMNNAYRMYQIAYITMNNAYRMYQIAYITMNNAYRMYQIAYITMNNACRMYQIAYITMNNAYRMYQIAYITMNNAYRMFQIAYITMNNAYRMHQIANITMSDAAIACESILNPRIHAIFKIIVSYYTPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5G3</accession>
    <name>A0AAV4P5G3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Voltage-dependent T-type calcium channel subunit alpha-1I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CACNA1I</name>
        <name evidence="8" type="ORF">CEXT_314121</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004000">
        <property type="protein sequence ID" value="GIX91169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5G3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008332">
        <property type="term" value="F:low voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070509">
        <property type="term" value="P:calcium ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0086010">
        <property type="term" value="P:membrane depolarization during action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF230">
        <property type="entry name" value="CA[2+]-CHANNEL PROTEIN ALPHA[[1]] SUBUNIT T, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00169">
        <property type="entry name" value="KCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX91169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="369" mass="41807" checksum="40BD06AAC2D77C4C" modified="2024-11-27" version="1">MAMEFYMMPQRLESALRAFNYFFTAVFILEAAMKMVALGFLKYLKNRWNQLDVVIVGLSIAGIVLEKMESDLIPINPTIIRVFRVLRIARVLKLLKMAKGIRALLDTVMQALPPRWAIWDCSSSCSSSSSPPWESNCSGGSSARRTSPARVWGSTRTSRTSGWPSSHLPRCDGRQLERNHEGHASRDVRPVGGVRAQLLPLPLVAPLYFVVFVLAAQFVLVNVVVAVLMKHLEESHRAADDELEMERELLAEEQEWRREQEQAASARPHKTLIKMASLPPNFVFPFDGTDDPSVRRQSLGQRLSLDCGRPDVNIRQASPTTRARCPWPTSAPPLPRGPGRLFLRDEQNSDFYFVYRKTEESFPKKDSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBJ0</accession>
    <name>A0AAV4PBJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_641781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004371">
        <property type="protein sequence ID" value="GIX94408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9124" checksum="19B9936897484C56" modified="2024-11-27" version="1">MPYREPSSIPISALRQFSNVARKLPTSYLDEFNDICLLKPPIYFKIVSLPPQSILIYRSQHIIGPMLQKPETKTDVKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PD68</accession>
    <name>A0AAV4PD68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_180041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004460">
        <property type="protein sequence ID" value="GIX94978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PD68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="274" mass="32297" checksum="E4710528D4709B2C" modified="2024-11-27" version="1">MWRKKLPEGSQFGDEELIMVFRYKPDIKNVMRSMENWDKGIFPHMNVQSLNQGDVLYESGKLDEKILESDKKLQNITPTIQDIHPKSRQNDEKAHNSLQHTTHKRPSVFYEEVQDDENFLDAVSTTQIVHNLPEKHEDEEKLCIPPIQDRISKSLKCLWISMDIYASQTSKVKHLTLKTFVIVDLMTMTKKKMNSHCTKPIQCPKLKFQKALEMMRNHVLSKMLFENILMILSRMKAMQKCFCLEILSNILLKNQTNRYKVIKHLKKNFSTIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGE2</accession>
    <name>A0AAV4PGE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_54427_1</name>
        <name evidence="2" type="ORF">CEXT_366481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004650">
        <property type="protein sequence ID" value="GIX96437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="20528" checksum="644650D11D2028C4" modified="2024-11-27" version="1" fragment="single">VASSDPESIGYAGSNSIDSGYKSLCATPEVSDSLSAPEVRRSASDVSASDSSTTSGRPRSLDGQDGKSSKIKMGTRSIAGKLKAMDRSPRHVRTSSAMNDVNLDHLMYLRQSLRKDRPDAQRSPNDSIASSATSGTFRDSDLSPRTITDEDWREQQCRPYPFRSATSSSSDSMFAAREGRSSRESCRGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJ66</accession>
    <name>A0AAV4PJ66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_640011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004745">
        <property type="protein sequence ID" value="GIX97164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJ66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10946" checksum="5AC470DD9EB818A7" modified="2024-11-27" version="1">MAVRYLEIRLPQLRDPYQVALVTYALLEARSVEAELVLSKCDLLLTHPSCHHRLNECHSELMNSCERHQEYESCEIEFESWRHRVYGDDRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLJ0</accession>
    <name>A0AAV4PLJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_116611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004820">
        <property type="protein sequence ID" value="GIX97810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="23" mass="2575" checksum="15C18D263D8FB12E" modified="2024-11-27" version="1" fragment="single">GPEPPLRGKRSTASTVEQRWKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRH1</accession>
    <name>A0AAV4PRH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_204131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004979">
        <property type="protein sequence ID" value="GIX98903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8459" checksum="2BCB2F2AEB26E9DD" modified="2024-11-27" version="1">MISRRHSTCNRDRNSILGQSSPFFDVARDQSLQGGHKTPFRSLQKRVCFMTAGNKWNVLFKNAQFVAGRWEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PT61</accession>
    <name>A0AAV4PT61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ homolog subfamily C member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DNAJC3</name>
        <name evidence="10" type="ORF">CEXT_674611</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005035">
        <property type="protein sequence ID" value="GIX99348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PT61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000224">
        <property type="entry name" value="DnaJ and TPR domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043988568" evidence="8">
        <location>
            <begin position="24"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="334"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="388"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX99348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="499" mass="57735" checksum="9AFDD703F00D6876" modified="2024-11-27" version="1">MLLPPHILVSLLYFLREIADVKSEEWLNNPDIDRHIQLGRELLTQGLYDDALSHYHAAVEADPYNYLTYYTRATVYLAIGRIASAIKDLTKVIELKPDFTSARLQRGNILFKQGKLDEAHIDYENVLRIDPMNNEAHHGYNLIDPIKRDIQLAYALVADHTYHEAVDVLTRLLQEIPWDSKLREMRAQCYESLGDLLSAISDLRGILKSQTNSQLRYLKLSELYYQIGDTEESLKSNSIRECLRFDPDHKGCFTHYKYVKKIAAHLKAMEDFVKEGNYADCIIRAEKAIPLETKVPRIMYILRAKHCKCLNKAGRTTEAVAACTEALKIEPENVDMLCERGDAHIDSENFDDALHDFQKASNLNDHSQRAHEGLKRAQKLQKQAKKRNYYAILGVKRTAGKREILKAYRKQAQKWHPDNFQGDEKAEAEKKFIDIAAAKEVLIDPEKRQKFDNGEDPLDPESQQFNPFAGFHHFDRGGDEEEWHVDNDDYFYVFVDDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PVS3</accession>
    <name>A0AAV4PVS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_603621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005157">
        <property type="protein sequence ID" value="GIY00252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PVS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10126" checksum="0BA72C8014640BD9" modified="2024-11-27" version="1">MNNKFEDWEMSRVKNERGRVKRDSQHYLVGFSPKSHVKWTVRSTCICGTTSPFPIEKELNSNPLQLLHLETTEPRNDIDSILNPPSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q234</accession>
    <name>A0AAV4Q234_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_676941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005453">
        <property type="protein sequence ID" value="GIY02534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q234"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21432" checksum="AE32E1AE47022296" modified="2024-11-27" version="1">MGQRPVRFIRAETQECPIGSIWELKHVAVLLKGGDWRGVSLIIGEGEVGELWISEKYVLHNNGESGRNFLVGEILCPDKFICVSCFVVYRRDTECLIGSIWELKRVVVLRRRGFTLIMEKGEAVEGEHSFYNRFPTAPSGDPENVLFMTVIYPILFLREFLQKPLFNFLKKIAMGSISVDKHFTTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGX1</accession>
    <name>A0AAV4QGX1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein 34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Rbm34</name>
        <name evidence="5" type="ORF">CEXT_103921</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005973">
        <property type="protein sequence ID" value="GIY06558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGX1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12395">
        <property type="entry name" value="RRM2_RBM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034221">
        <property type="entry name" value="RBM34_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050886">
        <property type="entry name" value="RNA-binding_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48024">
        <property type="entry name" value="GEO13361P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48024:SF56">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="270"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="375"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY06558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="507" mass="57776" checksum="CB67B2E718DFA332" modified="2024-11-27" version="1">MPKYKVGDVAALFSKPSVPQTNTGKKLQSLFDKIHNKSKPSKVKVEEKELSNVGEKMSKVENKNGHPKKVKKSKTEPVDDETYFPRNKKKSKNFNLIQEKSSVFPKMHFDENEDDDFSLSKEQPVKKIKNADKSEIEISENSSFETKKSLKKKKKLHQALEKDDLTKSVVEKKANIKQSPKKMSPIKKKKEKKIKMVQQDSSDSEVENENLVDEGKVEPRKSKILFQTSSKSTSIKNNSNSADSLEKEIKISKEKEPHTKPEENKERLSRTIFIGNLPMDFSQNALKQLFSPFGAIETCRLRGGIPVKESIPKKVACIKNKFHTGQKHRIGFVVFKEEKDAANAETMNGTLISDHHIVVNRASAAGNKKQYDEKRSIFIGNLPFDVDDDAVWSAFAECGEIEAVRIIRDRDSGVGKGFGYVLFKSMQSKHDALALENVRVSDRIIRIKQVQSSTKKTINNKQNALKRKVYKQRNKEGNRKSLKKLMKRAKICYEKKKIAKAFKNFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QH47</accession>
    <name>A0AAV4QH47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_799891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006128">
        <property type="protein sequence ID" value="GIY07599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QH47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10767" checksum="DA2C70E347E2E090" modified="2024-11-27" version="1">MLSNIPQQTLFFNQVLCTLRHTDYLIFGTYHIKSSSFNSTQKPPCFTQKENPSGKVKEIRDEVNKTLYTHFSTIPSSFRSNHPLVHLPPEFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIP3</accession>
    <name>A0AAV4QIP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrator complex subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ints5</name>
        <name evidence="3" type="ORF">CEXT_164301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006215">
        <property type="protein sequence ID" value="GIY08211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040316">
        <property type="entry name" value="INTS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029444">
        <property type="entry name" value="INTS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029445">
        <property type="entry name" value="INTS5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31697">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31697:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14838">
        <property type="entry name" value="INTS5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14837">
        <property type="entry name" value="INTS5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrator complex subunit 5 N-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 5 C-terminal" evidence="2">
        <location>
            <begin position="231"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY08211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="916" mass="102438" checksum="BF7245533A63000C" modified="2024-11-27" version="1">MDKLESFPPADVVLHQLQIFLNGASRLSKVRSAEVAHAAICLLKSTDAAREAVLEHAYNLFDESVNNFLKLEVSDRDPEGIGENDNIVQEMYNVLSDYVDKEAETWAPIISSWSLELLGYLSSKYADRRGVLHATLPEVLQLWMSCQPTRMLIDLTTQCLSTLVSSNPDSCIDALIETSVRHSPHFDWVVAHIGSCFPNTVITRVLACGLKDFMQQDITDEAQMSTNKNPKIASVVGILGHLATHHDSDTRGAIHSLFHESFSDSATREQLAAGPFLLHLAAMSDTLSHVISSEFVKVVNTEVLNKMYHQVEKWKSSKIPGTEGLTNLVVHLLLRSDGGCQVIRCLLNIMPSSTVEIHAGIKSAAGLILDSVLMEIQRRAYGGAAEIPLLHFLKTHVADLTACLIHPETSKASWVLNLLKFICFHGEEPATVFVIGFLMSNMDGVAHYISNIYQDIRMHQPNALSETLSRQMAELKSNRLAKPVILIQNIVGLCQKDPWTPLIIKGMAPNMEVLAGQITCRDTNYSDVVIELLSICINPKQMPMSSLFVVCSSVMCYFFHLLGRKELDPVIKITLVNNIKNLLANLCQQSSAQHAVLRMLLEGVLDKKYSVLFGARLKTDGEKSALETNLLNENVKYMSSITLPQSHSSVFHSGIIGSGLRITKNVPQLQKDVVLHNKQIILDILQACCKASWRFPLDDTQNVNNSLIPGMKIVALLMVELISPDVMFNGLPWPDEDYLKVTVERDLHIKRMFEDYPILWDILSLVANNHPSLCYCSVLLRAVMAVLLSFWNSSQEKATTNCPKELATSQRLINIMAVGQLLPPPLSYIDEVLPVVTPYEAFNLLSDIWQYMRDNVPSPALFHSKGPNSTRVWRNFCGDKKNEGKQFCDKKYINRLRFILFANIEKFGVVYAKFFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIW0</accession>
    <name>A0AAV4QIW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_585181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006345">
        <property type="protein sequence ID" value="GIY09232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16198" checksum="726D2F8A40693AF7" modified="2024-11-27" version="1">MLWISFPKVEKGFSTPPPIGPHKLISTWSSHLSPTPPSPVFIREAPSTSRFRHEVATLALYLLLQFLSKKYTTSANGFLWIQILFRVLLPTIYQGVSFFRCTGIRNAAVLNVIFLWELQCCHAVCFALSQWFGEGEVWRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QKA9</accession>
    <name>A0AAV4QKA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_115011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006438">
        <property type="protein sequence ID" value="GIY09855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QKA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12954" checksum="5BE9E4FE1524026F" modified="2024-11-27" version="1">MERRPFGHHRTFYFEACPRGVISLLGSRLKELGHPSKEYSRHLLQSTRSNYLCSNCVLDMGIRYGDQAGQYIKNLYLTEIRQLNRQLQTVLVSHLKEFRTNSIIEKGNIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNX9</accession>
    <name>A0AAV4QNX9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase aspartic putative domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_115071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006438">
        <property type="protein sequence ID" value="GIY09867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13686" checksum="1D938B57FBEDA69C" modified="2024-11-27" version="1">MRLRPVGRSTGYQFDFLDQDIICGVIPRIPKGPLMKELKGHRIWISDVGDDYPEIELLIGSDIYGQKILTGEVIQLNEGLTAINTKLGWTLCGEPKELNVQSLEGAQSMLITNLHVPKYESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRR4</accession>
    <name>A0AAV4QRR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_11351</name>
        <name evidence="1" type="ORF">CEXT_149841</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006776">
        <property type="protein sequence ID" value="GIY12358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01016076">
        <property type="protein sequence ID" value="GIY81078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRR4"/>
    <dbReference type="SMR" id="A0AAV4QRR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044659">
        <property type="term" value="P:viral release from host cell by cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00736">
        <property type="entry name" value="lambda_lys-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.530.10:FF:000009">
        <property type="entry name" value="Lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04109">
        <property type="entry name" value="ENDOLYSIN_LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034691">
        <property type="entry name" value="Endolysin_lambda_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17825" checksum="94F8E9A512EAA03E" modified="2024-11-27" version="1">MVEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLKSTGAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWC5</accession>
    <name>A0AAV4QWC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_618011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006815">
        <property type="protein sequence ID" value="GIY12606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="335" mass="35680" checksum="768CE374BA91F0A1" modified="2024-11-27" version="1">MAEELHRTTKRYAKQEVSERAVASRAAARRKWGRERNAEKNVHIYVYIWGLSDGRVTRALGSDALGSDGRVTQALGSDGRVAKDLGSDGRVTQALGSDGRVTQALESDGRVTQALGSDDLESDGRVTKDLESDGRVTKDLESDGRVTKDLESDGRVTKDLESDGDLGSDGRVTKDLESDGRVTKALGSDGRVAKALGSDGRVAKALGSDGRVAKDLGSDGRVAKDLESDGRVTKDLESDGRVTKDLESDGRVTKDLGSDGRVTKDLESDGRVTKDLESDGRVTKDLESDGRVTKDLESDGRVTKDLESDGRVAKDLGSDGRVAKDLESDGRVAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZ26</accession>
    <name>A0AAV4QZ26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_720681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007037">
        <property type="protein sequence ID" value="GIY14039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZ26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10130" checksum="95EA9121128141F3" modified="2024-11-27" version="1">MILNNTDYDMILNDTNCDMILNDTNCDMILNDTDYDMILNDTDYDMILNDTDYDMIFNDTDYDMILNDADKNNRAIVILRLFGVGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R583</accession>
    <name>A0AAV4R583_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_371441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007396">
        <property type="protein sequence ID" value="GIY16645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R583"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10169" checksum="40C75B1760DE89E5" modified="2024-11-27" version="1">MHSLITARRDASAIHTSPTAIAVLIDTVPNTIGFSAHAMVIYIPAVNNYLLKCPPFISRHQWIPTPTPILVTLLSQNALICKGISVVIAVLCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCM5</accession>
    <name>A0AAV4RCM5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dystrophin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dys</name>
        <name evidence="2" type="ORF">CEXT_62191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007574">
        <property type="protein sequence ID" value="GIY18071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="317"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="564"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="670" mass="77860" checksum="887639BB165038BF" modified="2024-11-27" version="1">MMEGLEKYIAKLQQFQNEVSGLMNWMQDVDQFLVAEDPAVGDVSTLEAQLEQSNALQDDIKTLGPNKKWEKVVEQANSKNIKLKDALNGSNELAEIMSELSEWVQKLESEIPEDGPISNSSDLLSKNKKLQFLSNKVDKRYQEYEKLSSTFTNISNSSQQNSLKSLSEEFLILQSKWENLVMRENDWLDRLEKKLKRSPESAADAEEISENLDDLENYLRHHPSDRVPKIQKIGQYLISNDVLVTPVERDVNLVTRRFEELSRQGRDRQQLLENSIAEAQQCERHILTVQAWISHIDTVLQNRLDNDISSQDVPEELTQLEAEFSEKEQSIKSLQEDVENYRSRGRIEAAHRLEEQLHLVEEKFSELQEKFIKFQTPCNFGNKLNHIGTMLNQVEDGLNSFQFSSEDSDSSESQLEKCLQLYKVLSDLKPELEQCIRQGRQIADSKQSDLKERLEFYKNQYNVLGSRFGQNCISCMERCFPNLVFASHRSSLSLVGCHFYWFCLVTENRALLENAIKKENNLEGEIFHFQEWLHAARMDADKTAPEKLKMLVKWKFNYEILSEVRNKKNLLDSLQEKLKILMNHLKKVLLNCSMSIQCLNKKLIKRIETLKGASKEYSKDFFQSLAEVKNWLQSAASFVYNLRNFLINRNILKLNKKGLRFVYLLGKNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQL2</accession>
    <name>A0AAV4RQL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_636821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008234">
        <property type="protein sequence ID" value="GIY23091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="16069" checksum="25525AFA46788426" modified="2024-11-27" version="1">MLVASSVCDSADLHPLTCGHHRKGISNYDIMISGLVAKMLQQNNGVRNKITANGLIISIPIPIHGTAIGFIICIPIPIHGTAIGFIICTPIPIHRGLEIKITANGFIICIPIPIHGTAIGFIICIPIPIHGTTIGFIICTPIPIHRGLEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQQ8</accession>
    <name>A0AAV4RQQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cell growth-regulating nucleolar protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Lyar</name>
        <name evidence="10" type="ORF">CEXT_471701</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008253">
        <property type="protein sequence ID" value="GIY23251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2100:FF:000002">
        <property type="entry name" value="cell growth-regulating nucleolar protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.490:FF:000001">
        <property type="entry name" value="cell growth-regulating nucleolar protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039999">
        <property type="entry name" value="LYAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014898">
        <property type="entry name" value="Znf_C2H2_LYAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13100:SF10">
        <property type="entry name" value="CELL GROWTH-REGULATING NUCLEOLAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13100">
        <property type="entry name" value="CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08790">
        <property type="entry name" value="zf-LYAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51804">
        <property type="entry name" value="ZF_C2HC_LYAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger C2H2 LYAR-type" evidence="9">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY23251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25339" checksum="8BD1ECF08991D854" modified="2024-11-27" version="1">MTIPVPIQCFCCFSLSLLDHFLSSWIWLFFINGREVVESLVLRIGEARGNGDSFGLRRIVGYVHPRRVYKVILTMVFFTCNACGQSVKKNQVENHTYQCRDCQSVSCMDCNKEFWGNEYKEHIKCISESEKYGPKDFKPKESSNKGELKQALWIQHINSTLETKKISGPLSGLLQQITQYTNIPRKKAKFENFLVNSLKIRNPKLISDAWEIFDQGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTX7</accession>
    <name>A0AAV4RTX7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serpin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_153571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008528">
        <property type="protein sequence ID" value="GIY25363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Serpin" evidence="3">
        <location>
            <begin position="100"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY25363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18921" checksum="CB030269ED0B8F39" modified="2024-11-27" version="1">MPKSSDILKEKFNVAGKNFTHIIGGGGKGKHMSLKKKGDTSRYYAFTTVFTNRHNLNGDWEDSYTIMLFVNFAALILVIPRVSSEYPLSFMYEHLMDSILDFSMTGFNLLVQNSPQQGNVLYSPFSIYNVLMMAHLGARGKTAQQICNTLGICHFNKTTVRFSFIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVB0</accession>
    <name>A0AAV4RVB0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">von Hippel-Lindau disease tumour suppressor beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_153551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VHL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008528">
        <property type="protein sequence ID" value="GIY25360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05468">
        <property type="entry name" value="pVHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.780:FF:000001">
        <property type="entry name" value="von Hippel-Lindau disease tumor suppressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.780">
        <property type="entry name" value="von Hippel-Lindau disease tumour suppressor, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024053">
        <property type="entry name" value="VHL_beta_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037140">
        <property type="entry name" value="VHL_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036208">
        <property type="entry name" value="VHL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022772">
        <property type="entry name" value="VHL_tumour_suppress_b/a_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01847">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49468">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="von Hippel-Lindau disease tumour suppressor beta" evidence="2">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY25360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17822" checksum="178B10066EC50B35" modified="2024-11-27" version="1">MDPLFRSSPSRRECRLGFINRTLRTVNIHWVNYSGEEINYGSLEPGHRKIVHSFEGHPWVCRDVFTKRKYFLNGNEVIIPRSKPEDLAKDNHSLSLIVNISFHVISMAEMCADLIAQHLSSLEDIQTLQIPTITKNLITESYETLHMSVKSVSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RX29</accession>
    <name>A0AAV4RX29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Rbp1</name>
        <name evidence="5" type="ORF">CEXT_766461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008745">
        <property type="protein sequence ID" value="GIY26888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RX29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12373">
        <property type="entry name" value="RRM_SRSF3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001074">
        <property type="entry name" value="Splicing factor, arginine/serine-rich 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="69"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY26888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21790" checksum="899789CB54019543" modified="2024-11-27" version="1">MLVNTDGLSLIEPIHRKLTKGVVLSSDVSFKIEASLPNIQERSETCCLAILLIYIFVMTRRFSDWDLDCKVYIGSISTRTTKDDIESLFSKYGPLRNVWIARNPPGFAFVEYEDRRDAEEAVAELDGVRLCGQRIRVEMSHGKTRRDRRSDTRRSPPQRSRYSRSRSHSPRYSRDRRNRSFSRERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SD39</accession>
    <name>A0AAV4SD39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_463281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009286">
        <property type="protein sequence ID" value="GIY30864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SD39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13153" checksum="6CD054A696020293" modified="2024-11-27" version="1">MGNTCYGNYKKKTLKWVFHTEIAFACDLSTNRLKKKNCFGIETEIEEKHSYRLFSESKGNVRRSQHFGKERLLRRTLQLRYKETSNHSNGCLPGVPICVKKIIKAKREDEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SH97</accession>
    <name>A0AAV4SH97_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_576031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009522">
        <property type="protein sequence ID" value="GIY32541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SH97"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11895" checksum="7E48760602C592D5" modified="2024-11-27" version="1">MINLTINCSFVTILLSGPKFILLQTLLVLSETRKLLLQYTRLNNWRKRRPIRAHRQQTMRIQKDYFRNYSVHSGLRKARVDRSSCSSQALIYRGQLTSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMW1</accession>
    <name>A0AAV4SMW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_510431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009669">
        <property type="protein sequence ID" value="GIY33677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8605" checksum="56B4C18AFE70EE06" modified="2024-11-27" version="1">MHWRAVFCRRSENRSAPSSRRMESSVIRRPSLSFPSPEASLSLVLLKIGSVGHGNSAFSRRIFKAKNAEDYVAPSIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY94</accession>
    <name>A0AAV4SY94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_371561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010256">
        <property type="protein sequence ID" value="GIY38106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11741" checksum="029E6B10C237D8F3" modified="2024-11-27" version="1">MLGFILIKENHENQPSRGLITASMLCELRKDSHGAVANKIEDHPEAVFKLHCESSMHTIAAMLSRAFMGCCVSELHGCCSTSRIVFHSSCNVTPPSQSGAGLLDTPWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYG9</accession>
    <name>A0AAV4SYG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_499971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010303">
        <property type="protein sequence ID" value="GIY38429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12827" checksum="34D441A974AE8510" modified="2024-11-27" version="1">MPYWDGFQAFEVGTKITYPFELLYIPSPPSSSLAVDILSRHPGRRARCVGDILQIPAPNHIFFFCCAASFSAWEVAGSVVPSLIMGGAVREKVHIHVRSRRQIGNISRGRGTTQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2S6</accession>
    <name>A0AAV4T2S6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_732161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010632">
        <property type="protein sequence ID" value="GIY40605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2S6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11589" checksum="99FE117F91D4732B" modified="2024-11-27" version="1">MMNQNSNTLRRLLHHLPPPRPLKELSDLYIYQASPGIEHCRMSEDDKTSASFRDSLEDEKEDQTLLETPPTVPAAHHMQNLFAGENVGDGSNEPSSDYFTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5C3</accession>
    <name>A0AAV4T5C3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ciliary microtubule inner protein 2A-C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_5553_1</name>
        <name evidence="7" type="ORF">CEXT_315901</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CIMIP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010713">
        <property type="protein sequence ID" value="GIY41389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5C3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018902">
        <property type="entry name" value="CMI2A-C-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22146">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22146:SF8">
        <property type="entry name" value="PROTEIN FAM166B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10629">
        <property type="entry name" value="CMI2B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ciliary microtubule inner protein 2A-C-like" evidence="6">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY41389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="315" mass="36139" checksum="58F0139321D6B5F5" modified="2024-11-27" version="1">MPRTEDYHYSHGSYTPEPHCIPGYTGYLPGFGPHKLYQFGKTYGKMTHDIMARHPVAGERFSRILSCDCNGRGKRDDTFKVWQHEHSTSNPKYTNDMVPGYTGHVPKRESHCGQGFQKECRRGISDFQKLKMCESDCHKQSKYVPPEDLLPRGITFPTRLCERPEHRKVPSYATFTNPMNYGQSVYEMSDLDPRKTYMPGYTGYYTGKCFDMGVTHSRGAHQDLCDLTSSKLERLVAEKRPKINDWYRCPVLYPPEPPVLDGYFPPEFQPCNPVPGYAGHIPGYRECGLGQSFGRSAGNVMRQRELMFHDGLRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5H2</accession>
    <name>A0AAV4T5H2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stc1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_250661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010780">
        <property type="protein sequence ID" value="GIY41933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5H2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20502" checksum="50429129661652A4" modified="2024-11-27" version="1">MSIPSPRLANPHRVRITKLPSNPLQQKWMLSLSPAPLRAALGILTLLFQHPSAHAPLRPFLFQTTPPERISPPKASHNRRERDMSKNDDHQGSGVSTCLLCRANSRGFRDFEGSLSPPKGKEISKEQDQHTCDRCHKRSRKEDEKKILPSMTDKSQQTRIGYDKSQVRLSSSPLLTKHSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TC65</accession>
    <name>A0AAV4TC65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_474811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010846">
        <property type="protein sequence ID" value="GIY42417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TC65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14508" checksum="3C6BE5C7A1BEEEAA" modified="2024-11-27" version="1">MEHANTEKLSLKICLVDINFKEKNVGTSKWYSLKETRLSTGQKILGPNADKASTTTLEKVFQKAMLQMRDIFEYQIQINLPNLIRTHLRTTTFPVTTSIFNLIFYHFSFFLPFQLQDIFYSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGE5</accession>
    <name>A0AAV4TGE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_69521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011043">
        <property type="protein sequence ID" value="GIY43835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13079" checksum="EAAE6B72AC036B25" modified="2024-11-27" version="1">MRSFAKYISPLSQAREIRRSSVLFTIRSSVIGLAGPPRWNSLPKSSERDSLSLGRFDRRESTRSGIAPGFVLSFSVYIVNRFGIKGLFLEFFKKGVLLLVRRILELIGKDSHVQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIJ2</accession>
    <name>A0AAV4TIJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_498691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011243">
        <property type="protein sequence ID" value="GIY45217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12893" checksum="93172807624C391C" modified="2024-11-27" version="1">MIRHEMVKQTTIDSKMKHSLKSHISSRMGHKKTLFVQIPGLIFLFKSFAINIIFLLKISCRLFLLEANPCLFAVNVRKSKFRFQSHSNPCRMTAQNSIFGFTSHARFGDDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIL9</accession>
    <name>A0AAV4TIL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_562121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011422">
        <property type="protein sequence ID" value="GIY46468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8781" checksum="83C60E161A6719A9" modified="2024-11-27" version="1">MPPPGFEPEAWKDNWEFYESGSFGSGDLSSLETDGHWGKRENASDAYTKRNLAKESFPRTSVDWYVYFLEHSDVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIT7</accession>
    <name>A0AAV4TIT7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pterin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_498981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011259">
        <property type="protein sequence ID" value="GIY45307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9818" checksum="ABBE745521A675CF" modified="2024-11-27" version="1">MSLDLNSELYYQWHEPFESVVRFFRNTLLQVGWGQGHQKEVAMDVGSGPGGTTTQLVLPLFPRLEKVIAVDLLPHMVDIARASFSSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TP59</accession>
    <name>A0AAV4TP59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_95531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011707">
        <property type="protein sequence ID" value="GIY48373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TP59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="230" mass="26485" checksum="5EDD19234BFF5960" modified="2024-11-27" version="1">MKFHGQTSWEDRRQIAPPRQMKVSCLLFIYYIFPSFFPTVSNGILTAGHYLVTVGDYAQQSLSELKGKWPKESLSELVGLDNDYFKQRRAYVSCSERPCPNSRYQNTSDEIMTIGSKERVREKSAFVSRSGFPPKSLTKEKVHILHGRWCSPLKNYNPIRRDLTSQMIRASTPRWREGVGIELKKGDLIEGLNPGMMFFKEHPLSIHFPFSGRHNGVQECVKNVFLHAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UES9</accession>
    <name>A0AAV4UES9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012750">
        <property type="protein sequence ID" value="GIY56278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UES9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9731" checksum="3DCAC072753D6BAB" modified="2024-11-27" version="1">MNWAQSRMALCKVMTNFRRFDTVQGYIYIYLYIYGWGAPPTDVGVVLWRGVRIKGGVVARVGDFRSPEGMVRGFASTCFNGVIATAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHJ9</accession>
    <name>A0AAV4UHJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_431621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012899">
        <property type="protein sequence ID" value="GIY57382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10188" checksum="50071A0160BE003D" modified="2024-11-27" version="1" fragment="single">DMSSTNDLLPFRYNNPFYNTSANSKVLKLCHLSPAANREVSEVYDCKEHDVFTFPVPSAALRGRFFIHFNILRDSFSRRMDKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMP3</accession>
    <name>A0AAV4UMP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_105861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013152">
        <property type="protein sequence ID" value="GIY59068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10162" checksum="0F4316809D66B591" modified="2024-11-27" version="1">MAFLCSNCFSSLPTSLLGFNLYSIFSNTSRRKLCKSLTSKHLKTLRSKCTTPFITKPGACTQCHELAPIKITKRQILLLDSSLFKANVFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQ65</accession>
    <name>A0AAV4UQ65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_606971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013266">
        <property type="protein sequence ID" value="GIY60026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQ65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="24622" checksum="63E33385BC32599D" modified="2024-11-27" version="1">MQIHPKVSPSNEKQLTNCLLKGLLMPEAFLPLVEALVLHCSLSLFYNPLDVGHSKELFGCVSLIKGSTMDEGQPLHFNFRHTLHVHLFQSLHIRYTILHRLAGTNLTLPVFLLITTLKCHHKKSRFRVIALFICLPQFIFFRVLVLLTVTVDSHSEKDSYKTSRPSCSYLHLKVNTYIGKEHNKSVGWGVLLGRNMEEECFRLRSDSGSSVQNILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V406</accession>
    <name>A0AAV4V406_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bromodomain adjacent to zinc finger domain protein 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BAZ1A_2</name>
        <name evidence="2" type="ORF">CEXT_321791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013875">
        <property type="protein sequence ID" value="GIY64429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V406"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008623">
        <property type="term" value="C:CHRAC"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045740">
        <property type="term" value="P:positive regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031445">
        <property type="term" value="P:regulation of heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047171">
        <property type="entry name" value="BAZ1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46510">
        <property type="entry name" value="BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46510:SF1">
        <property type="entry name" value="BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17740" checksum="1E79E3165C466F24" modified="2024-11-27" version="1">MCPSALSKNKESSEVTQVILPERAVKSPSKPDNSKPKKPKDIPPSKIKYEVVNYSTGKTTIVKPECMSRPKGTLTKSRNKLFLKHHTQPKDGVWKVKEKVIEKEQMEEFQFSEVFCGPLPSYAVPPPDKKLHMKKCLTRNQLNHLVLVKKQFRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VA41</accession>
    <name>A0AAV4VA41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CHDH</name>
        <name evidence="4" type="ORF">CEXT_53771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014125">
        <property type="protein sequence ID" value="GIY66514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VA41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF227">
        <property type="entry name" value="GLUCOSE DEHYDROGENASE [FAD, QUINONE]-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="3">
        <location>
            <begin position="179"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY66514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="335" mass="37402" checksum="F3208A3D60B1890F" modified="2024-11-27" version="1">MFLGYHGVGGPITVEKPLYNSEIKNPIFEAAQKFGIRIGDSNGPIQTGFYDFQCFIRNGQRCSSAKAYLVPVENRTNLDIVGGAHVRRVLLNGTQVMGVEFDYNNSTYQGLDPKSTLRSLKFQSWLICLWVTISKIIAEYLCLFSWILKTLTDATIYKTVFGPYEDKPMALCLSQILHPKSIGTVRLKSTNPYDMPLIDPNYFADKSDLRDMVEGLKMCQKIMTSEPLKKAGVKPFETMVPICSIFKADLDKFFTCFSKFFVVTLSHQVGTAKMGDPKDPTTVVDPQLRVKGIQGLRVVDASIMPIVPSGNTNIPTIMVAEKASDIIKRNNKLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBE2</accession>
    <name>A0AAV4VBE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_380881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014216">
        <property type="protein sequence ID" value="GIY67246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12998" checksum="E31588BAED24BDC6" modified="2024-11-27" version="1">MRGGVLRWVKYIDLADLFTILSIQPALLHKRHCEKGEGVEREQSEGVAASSGFRYCFVLCRSTRFGGAHKEETLQSAIFYATIPEMQYKNAAHQKSIKQKSYTMMDLPEDEHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VD01</accession>
    <name>A0AAV4VD01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_791981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014334">
        <property type="protein sequence ID" value="GIY68147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VD01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11990" checksum="6749E173A61FA21D" modified="2024-11-27" version="1">MGEASLREYISGGGNGGHFFPFLLYEEESPSIEKEQNYHRFLSLSPLLTNFARIRGKDSMVPTLPQLNEMSPIILRGILLQAQSQLKNEEFIACPDLYLDLQNGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJ31</accession>
    <name>A0AAV4VJ31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_708661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014613">
        <property type="protein sequence ID" value="GIY69969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJ31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9116" checksum="D80C851951DFD5FB" modified="2024-11-27" version="1">MKISWGSTRTERNDIFVETDLLQGVPKAVPFSGRAEAPQHVGPHPVCAEVRQCARGPPGVVVWPAERSRGWLGEVKEVGGSVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJ58</accession>
    <name>A0AAV4VJ58_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_302061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014550">
        <property type="protein sequence ID" value="GIY69558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJ58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11924" checksum="0CB3E818FC40A064" modified="2024-11-27" version="1">MKQKEAIPQNGSTSYLKHKQFLLLPQIRYPRMSKRLKLVFQTRIRCNNQQPSLEARRSSREEAELFLMRYFHSNSYTFFFHFASAYQISLGNDSSAFCMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMG6</accession>
    <name>A0AAV4VMG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sex peptide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SPR_2</name>
        <name evidence="8" type="ORF">CEXT_1491</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014745">
        <property type="protein sequence ID" value="GIY71041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019427">
        <property type="entry name" value="7TM_GPCR_serpentine_rcpt_Srw"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053219">
        <property type="entry name" value="GPCR_Dmsr-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273:SF4">
        <property type="entry name" value="AT19640P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46273">
        <property type="entry name" value="MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10324">
        <property type="entry name" value="7TM_GPCR_Srw"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="74"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY71041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="362" mass="41372" checksum="AAD7F04057C67C3B" modified="2024-11-27" version="1">MESLLEIMNYTSLFLNDSSDFLDRNFSFWNSTRVALEFQESSPYYGEYLTIFRNCYGSIHGYLSFIVCMFGITANILNIIVLTRKNMVSPTNAILTGLAVADMLVMFSYLPFTFHNYIRNDLSEKEKFSYGWAVFTLFHAHFTVLSSQQRQPVLDAPCQGCHSSHVRCVYHLLYPSVHHFHSFGIPGSDGEVMYRVDFSEIAQRHDKLLEKINFWLFSVITKLVPCVALTALSLGLIRVLYETNLRRQRLKNRAETDRSHDRTTRMLLAVLLLFLLTEFPAGLLALLSGILGTDFFNNVYLNFGETMDALALINSAINFIIYCSMSRQFRDTFAYLFLPKCGKAQELTPVADPSRTVATTCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VP06</accession>
    <name>A0AAV4VP06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_760601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014876">
        <property type="protein sequence ID" value="GIY71967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VP06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="210" mass="24178" checksum="6C19C5503B979227" modified="2024-11-27" version="1">MSITIYQDETLLQALLATLRCGGGEEMYPLFRIQIPHTLPERQATSLSLLRETKECINRFQTFIFQNRMQHQYAYFLHHLNSVRRSITIYQDETLLEALLATLRCGEGGNCNPLFRIQIPHTLPERQATSLSLLRETKECINRFQTFIFQNRMKRFSKLQLQVGLRQGKLQEIFPFIIPSENNWALLMISSSTIVTTVLVVGSLPLSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VR45</accession>
    <name>A0AAV4VR45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_712361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014950">
        <property type="protein sequence ID" value="GIY72478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VR45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14784" checksum="7BABCF36743618F1" modified="2024-11-27" version="1">MPIDLKRMIEAIHPCYDGGSYHSPPCQWILDTSESPLAVSLSEVLRYLRLSSAKKKKPEKLKKRKKSTIGADFICVGRRQTIRFSSLLTISQSRNGTTAADVWLIGNFQSWGSTPARWGEISGLDSTVCHCGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSP6</accession>
    <name>A0AAV4VSP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Titin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TTN_2</name>
        <name evidence="9" type="ORF">CEXT_5091</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015052">
        <property type="protein sequence ID" value="GIY73271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000357">
        <property type="entry name" value="Fc receptor like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF32">
        <property type="entry name" value="MAM DOMAIN CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="36"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="135"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY73271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="32640" checksum="D66F0E38C0F8AF19" modified="2024-11-27" version="1">MDVTKTKKNDITTSKMSTNLLIGKIQASDIGFAEEPPVLNPMYVPSNLAIGDNIEIFCIVKRGSYPVQIEWFHNDKKVTSIQKYKITNSESSSHLSIGKIQPDDIGNYTCIAKNRFGQDSNTVILIIEDGMAEEPVLNPLLIPPNLSLGDNIELLCTLKRGSLPLTFKWLHNEVDVTQILKSKIAVNKMSTHFSIGKIQATDIGNYTCVVSNRFGEDKGTLQVIIDGNFGEGEAPVLNPMFIPPNLAVGDMTELTCTVKEEACLFHSRGETADDPPVLNPLVTPPNLALGDITELFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2K7</accession>
    <name>A0AAV4W2K7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_811181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015375">
        <property type="protein sequence ID" value="GIY75690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13183" checksum="EEE3E2D70DC2A3B9" modified="2024-11-27" version="1">MLDVNMHRRHFTNTGHSLLSDQIHLYKHLKNIPTTFRSRSTRCFCEINLGKSSYLCYENAPRADKTRLQRGRRSANDSYGYRSNRWLEVPERPNLESEPSQKKKKKKVCQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2Z7</accession>
    <name>A0AAV4W2Z7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_58621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015457">
        <property type="protein sequence ID" value="GIY76264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2Z7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12366" checksum="F25E4BBCEE5A12C6" modified="2024-11-27" version="1">MTLTTKIKNKNNEKESRKRNKYESIQKYRQASARKELNRLENRPKKKSLYLASLWALKTDKSSYKEGVCGLAEERKESNSIECGDSNSERRVSFLLIHALVRGHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WI81</accession>
    <name>A0AAV4WI81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_744681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016137">
        <property type="protein sequence ID" value="GIY81514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WI81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19662" checksum="C50FE8016AAD505D" modified="2024-11-27" version="1">MKFRCLKSSEWYSLSCLFTQTWCDSVIVYHATYRFVLELKIVHVKIPHFTVLSQFHVLISKASNCTDHSVILKEVNVPLWRNDDCERALKFHFWSQLQATSDFSLRRRRRARCVRVALGNLRDAAEMGEDLWSAKGTATGIKLVSFRLALDVVSQTPQASTPGLKATAPGSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJ21</accession>
    <name>A0AAV4WJ21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Paired mesoderm homeobox protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHOX2A</name>
        <name evidence="9" type="ORF">CEXT_209821</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016299">
        <property type="protein sequence ID" value="GIY82870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJ21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000182">
        <property type="entry name" value="Paired like homeobox 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050649">
        <property type="entry name" value="Paired_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329:SF543">
        <property type="entry name" value="FI01017P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329">
        <property type="entry name" value="HOMEOBOX PROTEIN ARISTALESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="78"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="86"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY82870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18344" checksum="08AFF5ECA168089C" modified="2024-11-27" version="1">MCCVFPSPPYKVYPVSEEKRKQRRIRTTFTSGQLKELEKAFQETHYPDIYTREEIALRTDLTEARVQVWFQNRRAKFRKQERLNQQKKQAQQQSSQKSNNSTSPSGNNSQSSITGHNNNGSSLQISSNGSSKDSTLENSKIVSSMMPPPPPPNTKSLNGMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLE9</accession>
    <name>A0AAV4WLE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_172361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016344">
        <property type="protein sequence ID" value="GIY83143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY83143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20332" checksum="7B6B760D1F11600A" modified="2024-11-27" version="1">MQDPCPGSPTVLYKKPTYITYKEKPALQYNPLNIHFSCNECGILRTSEKDNDIDAEIQRLCELLQPLLRQRVAMQTSEVNEEAEPSGISDNEMDVALYQLYEYLQQRFQERLQKVRQDPELNGHGPNAKAAAKMSTHKMSDTPEIAEKAANSKLAEKAAEPKVAEKADRPKVTKRSHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLL8</accession>
    <name>A0AAV4WLL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leukocyte elastase inhibitor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">X975_03052</name>
        <name evidence="6" type="ORF">CEXT_605901</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016345">
        <property type="protein sequence ID" value="GIY83154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043820103" evidence="4">
        <location>
            <begin position="21"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="5">
        <location>
            <begin position="40"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY83154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="236" mass="26684" checksum="3C4A740419C5B3EB" modified="2024-11-27" version="1">MNSLLLLASFLASLLPWCLCQAGSGSQTVTFTMRKMAFSTNQFGIDLYRALNVTDENVALCPFCIGSSLAMVLLGAEGSTAMALRQALYLWGLHPQEVHLAYHDLIAHLGLNLTPSGRGVPRCQEIPRRRQCPEEIIDNIYIQRHFAVHFPYQFLLNRYYNTSVYPLDFVMNAEQSTRYINLFFERNTEGRVPHILSQVPSPSTNLLLLSAIYFRGTLDMNMAQVEESRFVGRAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQA4</accession>
    <name>A0AAV4WQA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_109441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016615">
        <property type="protein sequence ID" value="GIY85105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15032" checksum="A29257FBE10BCF58" modified="2024-11-27" version="1">MSDSFHAGLPFLQNYPPSLAFTGLPTPSSFPPPSKLLWRRERDSSVRPESMALVEGVVDSPACDSSMMARVEGVIRSSSSSSSSPKDGRQKTSDDTTEELSEARGSPFIARNDGLLAACQKVYFRRLPNHPFSAKSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQZ8</accession>
    <name>A0AAV4WQZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Dscam2_99</name>
        <name evidence="1" type="ORF">CEXT_408761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016452">
        <property type="protein sequence ID" value="GIY83973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10790" checksum="6CA83A621B9101E2" modified="2024-11-27" version="1">MLVLTIAISQLWQRAEPPSHAPVRATPAPQITWIKKDGTPVSDVTGLRHVRPDGTLVFQPFRAEEYRQDVHSAVYRCVARNVCGGHSQQGRQCKSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WX77</accession>
    <name>A0AAV4WX77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_78221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016786">
        <property type="protein sequence ID" value="GIY86370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WX77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10547" checksum="AB5A3BE62DE25493" modified="2024-11-27" version="1">MKPKFIQQPFVNVQHVLRNRWIGYASFDDFFLFMIVNIHPRRFWNISIHKTIKKRKRLFNILVVSIQQQKALSSTVEEFLLTTKKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3K0</accession>
    <name>A0AAV4X3K0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rho GTPase-activating protein 44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Arhgap44</name>
        <name evidence="7" type="ORF">CEXT_507401</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017076">
        <property type="protein sequence ID" value="GIY88576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3K0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035020">
        <property type="term" value="P:regulation of Rac protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.555.10:FF:000001">
        <property type="entry name" value="Rho GTPase activating protein 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047165">
        <property type="entry name" value="RHG17/44/SH3BP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14130">
        <property type="entry name" value="3BP-1 RELATED RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14130:SF14">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 92B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="6">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="212"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="90"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="530"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY88576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="635" mass="70566" checksum="7E2A89DCA0BD51D0" modified="2024-11-27" version="1">MSSYSKEINCLPNRFWFETSLEKRMKKIPQVLLGTSMLESGNSFSKNSILKECSSVQTKLGTELLDYSNEVEKLVLKPISSVLDNEVHNINKLRKQLGKLVLDMDSARTRFQTAEKHSMQASMNSNFNTVGKVDNLKEELEDASQKVDQCRDMLATEMLSLIGKEPQLAQLFVRYHQLQASYHRNALAAIESSLPLLENLIQDFPQKPVYGCSLEEHLRVTNREIAQVIETSVSFLLEYGVQEEGLLRVAGSASKLKKLKSAFDAGIEPDLVEYIRDPHAVSGALKSYLRELPEPLLTNALYEDWMNAANFESKLQALWQVLQKLPAANLKNLRYVARFLSKVLENVDANKMSAQNIAIVMAPNLIWSPMEDASTLGMNMSTASLHTSIVDLFISYGLDGSSSRISSVIPNLNSDEEVNGNNLQVNGMDPCPSPRSPHKNIKKPAAPLPPALKTGDDHVGELIDFTDPSHSSPKEDISKCDEPKESAITIDVLRRSNDHSAEIVAYRPEKPAIPDKPNYSSCSLDRKSIRQSVNNPRLSRTGTSRPNDPMTRSHIERPSVPPLKAKRRKPPERPPRSTIICTEIVSSEAKSEVAGSSPPPVSPRSGEVEKTKPPRPQPPVPAKPKVIVQNENTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9E4</accession>
    <name>A0AAV4X9E4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_472981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017389">
        <property type="protein sequence ID" value="GIY91224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9E4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14581" checksum="3EB53EED2F5DF25A" modified="2024-11-27" version="1">MMSIRRFFNSNCYTKTRESRFLQEQHDLPTLMHFRHRVKKKEKKNVCKASASPSHTHFYIHRNGNGLTSLTESSMRSGRSLKKRCLGNREKETIIAWAFYRRLATHTQKKNYFLCTHLKRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB18</accession>
    <name>A0AAV4XB18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fibronectin type-III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_63017_2</name>
        <name evidence="4" type="ORF">CEXT_796752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017460">
        <property type="protein sequence ID" value="GIY91779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="1490"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="554"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="414"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="772"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="922"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1218"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY91779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1609" mass="185061" checksum="260CC4F77DF9E0B0" modified="2024-11-27" version="1">MSYTGEVKSVLKNKKLRVENHIYLPLTLMDITKCVYGNENCVDKAVNTEDLDSETWERNILNNCRDCNHSSPKIMNSEYYVKEAVLNAEMESENYRTELEETQKKLTNLTEQLDNVLKCNCKLGVGMDYVIATVNELQSLMEWTSEKKEMKTDSTVIFQKLQQLERIQKDLEKTATESEIIRSRAEQERALSISEAGTSQENNIEHKNILEDAKTTEILEAIEQEDQLAILDNCVKKIESLSSNKIGQSLDTKNDDVKNILLIDLHTPEPIEEHSESTPTVVTPCSKKKGSTDDISDSLGPNISEDEGLGEESRRGDSTGPSSFIEIQDSLSDIVRLSTEVQSPSSSEIIITDPEGHEKPKQWPSVKEQTDSLDICLCAIGNLRDSLKTKESQLLKLSAVQNDQKEIASLQEVIINLHKDSVNLKSELEKSKKENANLKEQVLELEEAENDARLQAQKLGEKLVFLQEKDTHFQAKLCETKQALEKCLQQLNIKESEEQDLKAQLKYMDELVHKYEDQIRTMEIVELALRKKLIEEEDELRAAERSIAQCKSPTFERGTQMYDTPSSKSHFHETGNSPNKSKNLSIITDELHSVHENVKKSIDICVQFPDENAVQKQYIDSSIQTENVILDTITSQVVNEKTTEKNTKVTGTLSGESKEKVQSSLTSQPTECPIQNELLKRLHQLVEEDAHLQQQLHYVDQINLTLWKKLHNLEFHIGECKKKNISEDCTSDSCLDSECDFLSSRPTSREQMCDESNTNSKCASPCSNRGIIACLDQSEQEIKERLSKLEQINAAFEKELELREKLYTEKEKKYGEWVQTEQRFIGDLKRLSDERDSLKTQVENLQKEKEDLSARVLELQSEMDRAKERHGSETAKIKKEQEEMTAQLQQKVDQLLAKEKAHLKQITNLKLERSKNSDKSESDKLKSSYVELQLELSRTRDEMRKRDEEFRIRLDDSRSKHVMEEARLISELEMLRNKNSNYDEMINNFQSRQSELVDIVKQKENDLELAREEYKKNMEITEEEHRAIEAELKNQLRQMEEETSVATRALTEERVRLEKELQENIDDLRCKEEVYKARISELESNVTHLHEELHRITGDLDSGFGSDIGSDGISNFRREKLLNQLRELRDREAELREKLDEMEQKEAAYRETLEHADRIVASVEQGYKNKIEELEISERNLKQRVGHLEEVESRLRGALHKERRSSDGRKPDDLVVELLEAEARENGLKEKLETLEQMQRNSMNKVKDLEKIRGKLESELSDKEELATNLKKTQQELETARKSLTKLKKSETDFKNSLQQTENILATTESQMKNKIQTIEEEKKALEETISELRAQVRDLKKKLEKISYKQEEQRMSAAIPNKTVMHSEIPNTSDADEPDYVDVDNIPEPQVISKPSATPVTNNLNKAAITVSASFPRYRESQKVTPVRKDNAIIQQSIPNSSDSYDDARQNLEDCMLRAMAAMKNDMEKKVSIEQSEKEENDYDEVLPRPTNLRVVQQVGSDTLLIGWNYVNPSILEGFEVFVDGNLHETVYAPDRTKALISGLNLKRPLRLSISALSRYGQMSELTALDLPPQEGNNGFYLHADDEEDDDTYDESLYGNRRPYSMEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB20</accession>
    <name>A0AAV4XB20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_195871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000062">
        <property type="protein sequence ID" value="GIY91873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10927" checksum="AC51288E0A1F53D1" modified="2024-11-27" version="1">MWCSECEVMWCSDCEVMWFVTMKYDSAGNLGSMCRVSSIRIHGALFKRSSRVPQGLLYWAYAGRKHGFAIFYTRTFALHMNLYQCFPSQKKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC71</accession>
    <name>A0AAV4XC71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_574381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017487">
        <property type="protein sequence ID" value="GIY92033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="19072" checksum="E160B7011B0F9DDF" modified="2024-11-27" version="1">MTINHAFPGLSNRTTRKSGHLVVQMRLAKDERIKKKRFPWCSLATWFAACKKTIRFMKSQSQIFHRSFRIKNFPLFAKKLLSKKKKKKKKSSREEVDKKKNHHRRDYLHLMIPPNLTCQTVVGALVSTYPLFQLVLDGLDLSFVPDDFYHPTRNLAFHSFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEK4</accession>
    <name>A0AAV4XEK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_107481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000224">
        <property type="protein sequence ID" value="GIY93039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12786" checksum="49CF5D2762E06FFC" modified="2024-11-27" version="1">MLRGIYTTHVKKGSDDALSDQTNVVTSDVVRYATCLPLQESSFFIQNWFNLFSLAHNFKPWPSKTTEMDFCVVFDSEYAVMQFPLLPPGVLLRVVSGCKVRALFGIQLVAMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFU9</accession>
    <name>A0AAV4XFU9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_283881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017726">
        <property type="protein sequence ID" value="GIY93957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20507" checksum="ECCDEFF28BA757F7" modified="2024-11-27" version="1">MSRILRGGGDWLFRQGQTFVGNYSKLNLCSPSRCNKSRRITIAVTFNKRYTVLVPSSLKYQSRQTSDLSPLHILWWLCRRMSIHVPGPRNLFLKYLQSGRNQRLEKIVFPAGEDSNWDVSDSTRGWGMVISPGQTFVGNYSKLNLCSPSRCNKSRRITIAVTFNKRYTVLVPSSLKLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGY6</accession>
    <name>A0AAV4XGY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent translocase ABCB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Abcb1b</name>
        <name evidence="7" type="ORF">CEXT_669861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000325">
        <property type="protein sequence ID" value="GIY93917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF645">
        <property type="entry name" value="LP14331P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY93917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="24294" checksum="61E34731E9745850" modified="2024-11-27" version="1">MEFFDNPKNSVGSLCSRLTSDASSVQGATGSRVSTLLQSLSTLCASIALALRYNIKIGMLVLAFIPFVLVAAYCEGRVVASDTEREKKGTEAASKVAIEAIESIRTVASLHEEHTFYKQFHDALLDPLRKSRLKSHVRGIIYGFAQDLLKVLEGVMLGAMMIGQSVAFAPDYQKAKVSAVRIFKLLDLRPKIDASSTEGNRLEDVKGFINFPKSLFQLSQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH41</accession>
    <name>A0AAV4XH41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_70485_1</name>
        <name evidence="1" type="ORF">CEXT_372351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000278">
        <property type="protein sequence ID" value="GIY93545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="471" mass="54752" checksum="F94FB835599F6B90" modified="2024-11-27" version="1">MPPISLYETCLDRIIELIKVEHWREERENPFSRLPPRIVELLVEVCGTSQEFKKFSYFRMLLSSGKLRILKLCFPVIFIDICVVLPQMLTEKGCLNITVLEMDKNFQNFESKWLEKLLQKLTLLESLSVRTLFNPQALNNCKGLKSVEVIQIFTNLIEFNNFISKAADTLSHLEDLEEFDIFQYTTKSSNFLKVVKILNNHPKLASLRFTDSSRAAHHIYGNRKGYALPVYGLRKCSWTSFEKITTLNISFLQRIRSSVLLFPLVEELEILVICEECFEYLKKLKYLRSLKIRFHIHSAYEADFSFLSGIGQQLRHLCIVSYQDVPVNAISKYCFNLEYLKIIGNATICDSIESSYSFRKLNRLEIVKINAHSLLCVFQSVRNLKELHLYMAAVLNDQRLLEILNINPLAFNHLDKVFVRDCMLSRVGFRIFLENAAKLTIAYIKSSHFSEGVRGDFSDVIKDLQRDVIHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRX2</accession>
    <name>A0AAV4XRX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_359201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000781">
        <property type="protein sequence ID" value="GIY97464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11156" checksum="E4FC3DF8D504FBFF" modified="2024-11-27" version="1">MCREKHHYSRTVHHFSPLALMSCRGNAAEPKINYHINFKVEIKMGKYLPSTTSIILVKNQNLDKSELKHPILSLELRMNRSLQIPLREHAKILSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTB5</accession>
    <name>A0AAV4XTB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_448161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018177">
        <property type="protein sequence ID" value="GIY97553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10956" checksum="0C90FC67C6DEE4E2" modified="2024-11-27" version="1">MAVGGVGGVRPSEKDIYSMNINVFPFSSPFVVLREKKMQDPSSVNCSKMPTANAEELILAGIIAFHFKKLKCRFRRILEEVLCLRSRFFLDAQVIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTG5</accession>
    <name>A0AAV4XTG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_165221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018243">
        <property type="protein sequence ID" value="GIY98019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12870" checksum="E52418FAA894827C" modified="2024-11-27" version="1">MNAQNIIILHRRLPPSHFKNFVETHREYRPTTAKRHAFGIFTSKRQIFENQKIESRFLNSLYLLRLFWRYFCSSDAEAITFERNKKDREGPWESILWAETCFSEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUX6</accession>
    <name>A0AAV4XUX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_739261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018196">
        <property type="protein sequence ID" value="GIY97654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13452" checksum="CC308487DD1A7A02" modified="2024-11-27" version="1">MRTRRRIKLSADPTPSRGLPGLRKNPSHGFRNSDHKREPLSPTFSSHPLEDPPHTDTHTCASLHTVFLSDAETLPAQLIFLPTIQALQASKHQTSRGGLASPHDQRSLFNASLERYTHKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVG8</accession>
    <name>A0AAV4XVG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_145541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000850">
        <property type="protein sequence ID" value="GIY97890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="34" mass="4043" checksum="F13D58EA3B4912A9" modified="2024-11-27" version="1" fragment="single">MGRKKAPRDESYRSSEKSYDEDLFNKFNACRRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0W1</accession>
    <name>A0AAV4Y0W1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018605">
        <property type="protein sequence ID" value="GIZ00957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0W1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12292" checksum="4A37F52279C37907" modified="2024-11-27" version="1">MIAGRRLEDRGGNLRMNAEFSGMTGGLKLVRGVPVMSRKQSNLSPISGTHVGSVCKPMFIRWPWDYSERNIGWFGKCAWTRMRCSGTKFKLQKSLFSVKKLKVVVALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4X8</accession>
    <name>A0AAV4Y4X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_673321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018808">
        <property type="protein sequence ID" value="GIZ02402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10810" checksum="D67FBD51D673FABE" modified="2024-11-27" version="1">MEGGSNSVNRKPGISNGSPNQYVYMDFQCLDMLATEQFCPSVSIAPIVVILRRGKRYVSSHLHTRISRLFDFRDNERHFTAQLRMNCYRLRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y730</accession>
    <name>A0AAV4Y730_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein toll</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">X975_13682</name>
        <name evidence="7" type="ORF">CEXT_504501</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001433">
        <property type="protein sequence ID" value="GIZ02294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y730"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365:SF541">
        <property type="entry name" value="PROTEIN TOLL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24365">
        <property type="entry name" value="TOLL-LIKE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043551345" evidence="6">
        <location>
            <begin position="32"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ02294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="444" mass="51172" checksum="3C1D053B1CDE56EA" modified="2024-11-27" version="1">MVFLRLLGLPHVSFILWIRFISSPLMPRCDGTRNPFHCDSQLLPFLQFLNSTEELIQMKTFAPFLIMVPRKPAFLSAALIPADVPVPMITSYLRTAAPLDSQICRLFFMEEHNSTVLKIFLPRSNKEVPFVIEAEIEGLNLSNNKLQSLEEARLPNRMRFLFLDHNLIRKPPVSLLESLEFLTSVTLSNNPWACDCDALDFKKWVVLKSVLVLDVKETRCGPDMPDRPGLAERSIWLLTGFGTLPRQHSYLHLHGFRISQFVLIDDQLKNRLDTVRDRREGVALLTRSDLGQGKDIDRDKEFDAFISFSHKDQDLVIQGANRGDRREGPGYQVVPSLQTLPPGRIHTKEHHEGREVLQENSPRALSALKDHVPRIIVIKLPDQPQDDELPEEIQLYLSNTTYLTWGEKHFWSKLLYMLPRSQSIQKHQFRNYTRLPICIANRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE88</accession>
    <name>A0AAV4YE88_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_709181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019094">
        <property type="protein sequence ID" value="GIZ04492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9587" checksum="90564388C941D9E2" modified="2024-11-27" version="1">MVSCQFCTSLLFARMNPTPAGVFFIARPPSRDLGRSFHPHHHRARGAEGTPRKNLFVADREVSAGCPRATAAALREKRRICKCTFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGA1</accession>
    <name>A0AAV4MGA1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_523481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002229">
        <property type="protein sequence ID" value="GIX71529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043450292" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8342" checksum="55AD94C57583114E" modified="2024-11-27" version="1">MIHWYLASDLLLLLMFSNAFSFESVQFAAQQSTGNGDCLQTRIFYTVCPSKLASQRNVSVAHAPLAISSSANEKAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMC1</accession>
    <name>A0AAV4MMC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_393781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019863">
        <property type="protein sequence ID" value="GIX72626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11548" checksum="6931489860B83F9E" modified="2024-11-27" version="1">MSEIKCDMRQDDVCIEMKPFVLKPARRTQRRTRNSVNKDSYCQSNYLNFKDYRNIHCNDQWIPNTPQITKKKYHKKKKNEHISLKLTIKMDPYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMT2</accession>
    <name>A0AAV4MMT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_675991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002428">
        <property type="protein sequence ID" value="GIX73577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8957" checksum="B804BC210136BD55" modified="2024-11-27" version="1">MQVSLYSVKLFSTPRTPYQNNIMHQEQGVLIFPENLIQINLHSATCENRGQALLKNTLHNNNSSTRAFQTSVPFPPTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPQ0</accession>
    <name>A0AAV4MPQ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fat-like cadherin-related tumor suppressor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_18588</name>
        <name evidence="1" type="ORF">CEXT_343381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020001">
        <property type="protein sequence ID" value="GIX73894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPQ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11182" checksum="EE913DF8990A16D7" modified="2024-11-27" version="1">MVSEEAVKNSVGMRLKGITPEDFILSHCKNFLHGLRSALNIRTKDIDILSIQPSEAAMSKEKRDTNRDLDVLFAVRKSPHVYFPSKQLLAKIKTTSNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MS89</accession>
    <name>A0AAV4MS89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_480831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020143">
        <property type="protein sequence ID" value="GIX75173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MS89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="26" mass="2824" checksum="70FC7B38CA43FAAE" modified="2024-11-27" version="1" fragment="single">MEPNGSFIRSLEGRFSPKMREAVGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTL0</accession>
    <name>A0AAV4MTL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_366301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002576">
        <property type="protein sequence ID" value="GIX75270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="291" mass="33223" checksum="44D8A5BEC7E72DD0" modified="2024-11-27" version="1">MDESWWKKLVSLCVSCMLATHGQWDSGFGKEGLFCDSLFCFFVRSWVVTVAGLRSIEEASNKRSELYLHNKGGKEVNGHVKLGRRKAGNEPSGGRLASSLLKQSGEPKNKTKRFAFYGSVPLICLCHDSVSKRAPTLKKRPRNSKQNSCLLLLTSEPHRNAYLFSSGQKRPARRSPFCDQSFRTTTTTTTKKKHCININRRIKWVPTGFRLEQWIFFVVCPSTLSGVFSQNQVKVGERLSEDLLNMTIYNRVQKRCDIESIEFLNSKQVRNRQLRSKLCVYSIDRHYASVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTP5</accession>
    <name>A0AAV4MTP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_28531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002621">
        <property type="protein sequence ID" value="GIX75782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="280" mass="31715" checksum="D57D1B315A6AC822" modified="2024-11-27" version="1">MSSFHFAGRTKLMFISDAAHSLLWKGHGVIESDESARWTLTMSTYTFVSNEGHLGLIWQPNSWRYDEIAPCPLEGNKITLTEVNVNKIECPLEWLPFPFWEKKASCACVSEFLVFWKVGTYNAAKSMAAGYMYTCSRHMARNLEYCLYLYDGNLVVLFGEGGWRGVDGKGPFNLLLAGVMARRKRGTSFPIMIGHRHRCHYDRMRKCVVCHVPRLFPCPSGGMEDRGVGVERGALSLSLTQWFHKVINPWRQAMGSNSSHSDLYCFCYRQEGSVVGIGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N606</accession>
    <name>A0AAV4N606_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_131421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003003">
        <property type="protein sequence ID" value="GIX80147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N606"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11137" checksum="779C6F29B52AD946" modified="2024-11-27" version="1">MIILIYQCKEAGLFQSFEIEGGAGKRSPCKKSIGILDSNFRSPCVVCLASVLLEQKKEQAAVKCHEKEKKQFNEEFAFDAASTWSRYANEKKIMDYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NG20</accession>
    <name>A0AAV4NG20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_607151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020898">
        <property type="protein sequence ID" value="GIX83725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NG20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9109" checksum="4E0996EDF4F7DF8F" modified="2024-11-27" version="1">MSVHDDISSDEKAVQISYSPFEMVKIPVKTIEPIHHRTWTSHLFHLALYSVGRAKSCSGRDLRFPANRRPLIAHYGHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHW3</accession>
    <name>A0AAV4NHW3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RNASEH1_1</name>
        <name evidence="10" type="ORF">CEXT_762281</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01003271">
        <property type="protein sequence ID" value="GIX82902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease H1 N-terminal" evidence="9">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="RNase H type-1" evidence="8">
        <location>
            <begin position="138"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX82902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="468" mass="53560" checksum="213A22B95B089D85" modified="2024-11-27" version="1">MNITEIEKQVTNSNVGRERESNLTSKQYVNCVKLKNYLNGVISKEKACKNTYTTVKKKVQLYYAVHGENPGVYRTWNECRKQMNVAGTVSYRKFCNEKLALEYARNGYIDKFRTVASKRKRDGRGEIECTRENPGESSMFVDEASEENGEKRVRIDIGIKWGLNHPLNASKWLSINQRNTCSDIKEAIYALNQAKQIGAHKVKIYTDNNYFMQVVADWTKKLKKINEGILVYDNSLANKDFLEFKAVIEGLYVEWIYVESHERSDSDDDDDDDEDEADREAAAEERILLEPSNYSTFPKPQIGPEIVNPLSTVSNLNEKMSKLVISGEEKERKTFYSAYIGEKIAAYKTHIEEREEQIKVFVKAWFKKLSKRNKTFEFVKYGEILKKIESPIPGPDKFVSVFINGVHSCNEQEQAEAGIGVYWGPGNNLNTSMRLSGKQTNDRAEIISAVHALQQAKKQNSMATSVHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIE1</accession>
    <name>A0AAV4NIE1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_620921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003438">
        <property type="protein sequence ID" value="GIX84562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18792" checksum="C4418F4E6F3A5DCF" modified="2024-11-27" version="1">MENIRGQKLTEFIAQHQLHLLNPTGSPPTFIRNGARGWPDLTLSYATTYNKIQQWKSTDYDIGSDDLTIHFQIQHRIQVPISQRYKTKFGNFKKFKEQLQTNLRNFKLDNIRTKEDLELQTSLLVQIIQSCCNSTFERKKELFRTKTYTMVEPGPQSPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKC7</accession>
    <name>A0AAV4NKC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">G-protein coupled receptor Mth2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mth2_3</name>
        <name evidence="1" type="ORF">CEXT_407211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003466">
        <property type="protein sequence ID" value="GIX84938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="266" mass="30210" checksum="D91C348040DE1685" modified="2024-11-27" version="1" fragment="single">TEFVLVNYQCVRKDNYEGDDSENDTDIAIPDAKANNVHLTFNAEMELFDFLQFYEQNISEICDSIRESFSTSFNIKIDRIRNVSFNISLGNFSSFNETLEFFKEPEPSVDSIVSLLASALSVNGFDLGIGNRTSRIYEIHQTVDFLESWCNPKEGGEMKKYWNSDFKLILNDNVTSTMGERIKNLINVSGLAVVCDWKVQLNESCARIILEKHEYLIQENGSVLILNGSTDSIDVSVFEEAENESIVVCLLSSKIIVDDDYYMENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKL6</accession>
    <name>A0AAV4NKL6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exophilin 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_63139_1</name>
        <name evidence="2" type="ORF">CEXT_539391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003508">
        <property type="protein sequence ID" value="GIX85330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="68774" checksum="4D6D9BE00196A009" modified="2024-11-27" version="1">MYAGVNSTGEITTSVAALDNDCSPDIPEWKKILIMKKRAGNNSTGVDEFSRNLDSSAGSVNIASRNGGCSNTFDNLAAGGNNNKFGRSAKVVEQDFREISPPKTVTIGHINVALRSVKSTPENQNTFSEISKSDRGSSGDFNCQEFDNGNCQDLQYGPGIVDRLRARFLNMGLKQQPKPVVRRFSSLENLPGSNAGPYRVNARGFRQNGFKPGTGSVKKAQSMETLIYTTPEQQIFASNRRTSARYVGGVKGRILKNVSPISVLTDENDEPREKSPSPAVSPRLFTKSIRRWDYNRSVSAPNINEDELPKPDTVKHVKKIFESPPLVANCSEKPSNHSGGARFRKIPGTTTTPTSTCNNGAIIGARPAVKKQDVKEEFPLSPEREVEKCDDYKINKGGCSPVLADNLSANRSHDTLLQANALSSNCSHQNLIDTPQLVNSFESEEETETSPKVTPEQLPPVEGDKHTEVLSQGSPISEVELLQEDEYQFTGVSSNADEGMVVAGGESFPKKGGSTWQKAPPATTSIVFDFRGKDVKPNISLNPTPFGCRPAKVSRSSKRSGSPPRTGINRDDSKSYIVDEELQNGEDEEDWDEMDIGADLPVVSGIVFSGENVKVGRGALLEKRNKKLSCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NKU5</accession>
    <name>A0AAV4NKU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cobalamin trafficking protein CblD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Mmadhc</name>
        <name evidence="1" type="ORF">CEXT_643801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003415">
        <property type="protein sequence ID" value="GIX84341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NKU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009235">
        <property type="term" value="P:cobalamin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019362">
        <property type="entry name" value="MMADHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192:SF3">
        <property type="entry name" value="COBALAMIN TRAFFICKING PROTEIN CBLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192">
        <property type="entry name" value="MY011 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10229">
        <property type="entry name" value="MMADHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="302" mass="34356" checksum="D7A0EEBA5D9C4FFF" modified="2024-11-27" version="1">MLIIARLHPHLQKQKYLTSYFRNLILRRNPAPISKANVSQANNDPRKEGYGEKEICLLAPIDIRAPFPGNIGVPSFETICTTKIKNLPKPAGDRWDLLIPLPAEKHHYIISQTAIVVNQKALSISDKLECYAHSCPELLKIDFGKMFPSKDLNQDDLSVITLCLKTENDMSTWSEEGEVEREKSSATFEIAARAISAYLQESGFWSDFIHPNTGKAHFNPVTNSTMFETDYRYRHFGFNIEDMGCCRIISHILWGTKIFVGAIFTNAPLETLEIRNIVSKDTEKITDSYRNPIINYLIDYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR15</accession>
    <name>A0AAV4NR15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_188881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021115">
        <property type="protein sequence ID" value="GIX86141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16265" checksum="7113B683377E90DC" modified="2024-11-27" version="1">MDRGCCNLETPGLETVPLCASIAENGHEDCLQKGDRSARVERELLAIALEASTGHALLSGSRALRIQIIIRSSACHLKRSPWVSFTTSLYLSLRTECEPHRFREVDSGITLGGESENLHHLFCQSCDRPWILTRKRFVHIKPPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRG7</accession>
    <name>A0AAV4NRG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_300421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003640">
        <property type="protein sequence ID" value="GIX87019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7791" checksum="26BFBE3241C880F7" modified="2024-11-27" version="1">MIRGSITEPRRKPNHDDVIRGFFLSVKSAVLGTYPVSAAFDDRTLSFHSLEMEETRSEWFPNYKSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTG8</accession>
    <name>A0AAV4NTG8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_38351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021217">
        <property type="protein sequence ID" value="GIX87231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="24320" checksum="13C655C34C2CBFF6" modified="2024-11-27" version="1">MDIESNRSHLYYVCKNPIHGRWLDQKQRDISYSSWRSKFRNMLSFLFSPIAKLSPCFKRSGVFSTLKNIELRHQISSRKQGRLTHSPALSHHPRSTSRRIRGSPGPTEEEQFLRGTMCGPLTNSESSFFFILSVIRMFENRDSFFYFFRDTLQGENSRPPTKLCNEVRVALLTLQLYLITRDGHLKESEDPGDPLRENSFQKKQFVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NX92</accession>
    <name>A0AAV4NX92_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_623421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021433">
        <property type="protein sequence ID" value="GIX89522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NX92"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="35118" checksum="2142AAA6B9D1D678" modified="2024-11-27" version="1">MDRDKAETKLWTDLYLSCLPSGGLESIIKDESFSVLRGMNFRWLMQGEGRGHMCTCTLYVIHHGTEHQTDFVLQEKKGDLYPPQSTNKAVLHGLSRWFSKGALLPLGVSGRITEDNGPPSNALGRSFNEIMEMTRDCIYCSFPSLDLHSTENCPPKSTLTLLSTLPPIKERPKLLLNEVAHPSIPVPVTRQGYVILKNKYKKGKGTPSTLSPNFSKGTPPPHPPKRQTLRRATHAPRCTMVLIGQTGVARVPYKFEGAMPFSLPKVSDFRRSHHPSPADDFSLERKGFESILSNFKKSKSFLTKDFSIVQFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXM3</accession>
    <name>A0AAV4NXM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_420831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021445">
        <property type="protein sequence ID" value="GIX89642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10152" checksum="61B96A1588745C2E" modified="2024-11-27" version="1">MVFRKLEVQNFFRKTLPTAMKQTIQENTTNILSKIRVELKEFTLFVDDLQKKTPQEWQLIAVCSTPESPTGTETSNSKPFTSNTLVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZI9</accession>
    <name>A0AAV4NZI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_67811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003929">
        <property type="protein sequence ID" value="GIX90317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12287" checksum="32E87F8A5468C255" modified="2024-11-27" version="1">MPLFLIKIANSLNAEEIFKTDSLLGTKISIERFSGSNTAPQCRNCYGFYHSSETCPLKPDAYTAQQNTPPQTAPSLKIRAKHAGTAMDHTSPTGEDAPGSQGKNTSNPKGNSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P073</accession>
    <name>A0AAV4P073_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon 17.6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pol</name>
        <name evidence="2" type="ORF">CEXT_126601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021500">
        <property type="protein sequence ID" value="GIX90418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P073"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="83"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="294" mass="33444" checksum="CBE0AF44117FCF74" modified="2024-11-27" version="1">MVTNINWEEKLDLNHLNQDDKTKLLTLLDRYKPVFAQSESDLGSCDIVQHEINLTDKLPIRQNPYRVPYALKSEMKHQINTLLDAGIIQPSNSAYSAPVMLVKRRDGSYRLVADLRKLNEKTILDNFPLPNLTEMIEMLSGARYFTSMDLTSDFHQMKMHPSSAHLTGISTEFGLFEFKRIPFGLKNASASFQRLMSIVLAGLSELQINVYNDDVIVASKTVQEHLQKLEIVFQRLTAANLKLKPSKCSFLQKQITYLGHTVKEGLVLPDNKNLDSIRKALPPKTKKQVRSFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1W1</accession>
    <name>A0AAV4P1W1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_692871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021548">
        <property type="protein sequence ID" value="GIX91029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1W1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="52" mass="5885" checksum="189A2D7830BEF5C0" modified="2024-11-27" version="1" fragment="single">MNRWLDSLVPSFFYEKQQQCQGTIDQQNVLSQAISVCGGDEPSFLQIWCSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P353</accession>
    <name>A0AAV4P353_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fibrinogen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_807651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021584">
        <property type="protein sequence ID" value="GIX91456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P353"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12998" checksum="534F2BFCD188D41D" modified="2024-11-27" version="1">MPKESVDLQFTKSFRIDDESRNYTIHIKGYGGNAGDGMKFHDGQRFATIDRDHLRGATVLQGAWWIYEWAYVHLNGIYIPGIDDPRSIHWYLWHKNEGLAHVEMKIRPRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P480</accession>
    <name>A0AAV4P480_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_380331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004064">
        <property type="protein sequence ID" value="GIX91839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P480"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12087" checksum="1F9FC7C5EB54C103" modified="2024-11-27" version="1">MSTEAILEEIVTDLLNAEIPDLKEREYICKACKANKPPRNFAYNKFGGESSASLTSTDSSDTIVLFEDENERKEQQSIEDSLVCEFFCGPTLGRQEEEEEREKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4D9</accession>
    <name>A0AAV4P4D9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein 521</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">X975_21748</name>
        <name evidence="8" type="ORF">CEXT_498261</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021583">
        <property type="protein sequence ID" value="GIX91440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4D9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="379"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="411"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX91440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="457" mass="52021" checksum="0F5462E2237CE801" modified="2024-11-27" version="1">MLSLPQNEEEVQNLSMKSRENGGSTVGFSSKASFRCDMCDSSFSGETTLNVHRRQVHNIRNSGSQKPGQTTLSKVCAYCNESYKSRTELENHMKSHGSLCPSKHKCNICDEICPSAATLADHKISHCKVVTDNTCVTCHTPLKLAEHFYAHLKQHNAQGLPASCVVCRQVLMSEIEVEKHADHHLKNTESSRFCCVCGETSPPEQLIVTGTQNSHSYMCRKCFLGMNGEDLRCFECKVKFETFADLEKHKLNHVHTYNCIKCQMNFSTNEEAQAHIKTHVSQEGPDHRCHICPKVFDTPFKLTCHLIEHNFEPSSVYACYMCEASFTSPHLIRDHMVEHGMHVRRFDCLFCYQRFFFKAELDNHLIFSHPIPTNSTDLFQCKVCGQFFTSPEHLEEHSKYHGKQSPTTKRLKCSLCPESFDSVVELKQHHFGDHNGSEIRDFKISSPALSATKYFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PH52</accession>
    <name>A0AAV4PH52_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Metalloendopeptidase</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nas-15</name>
        <name evidence="11" type="ORF">CEXT_755211</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Zinc metalloprotease. Provoques deadhesion of endothelial cells from cell cultures, and also degradation of fibronectin, fibrinogen and gelatin in vitro. Its role in the venom is not fully understood but it might act as a spreading factor that facilitates diffusion of other venom toxins. Alternatively, it might be involved in the proteolytic processing of other venom toxins or it might play a role in extra-oral digestion of prey.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="BPLR01004567">
        <property type="protein sequence ID" value="GIX95835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PH52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="10">
        <location>
            <begin position="37"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX95835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="26289" checksum="A1818BA8B8AB699F" modified="2024-11-27" version="1" fragment="single">DPSFGIKSPGAALSKTQSVVPQKTLCWVSKTGSSQRASILCIDSESRQKSSHSLNIRCLRQQPGRGKGRFLIAKAMLEFHKSCCIRFVPRTTETDYIEISPNGGCSSHIGRVGRAQSVTLGRGCYTVGIMVHELMHTLGFVHEQNRPDRDDYITVLWDNVKEGLEGNFVKLEPYAVQSLGEPYDYSSILHYSKFAFSKDSITKPTLEPKKRGCSVGQRKGLSAGDVRKINKLYNCGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHU5</accession>
    <name>A0AAV4PHU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_484021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004709">
        <property type="protein sequence ID" value="GIX96907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8679" checksum="6A3412BD3EA2769A" modified="2024-11-27" version="1">MVCLLPSDEHCKAFCTGCNPVILPSGQHAPPSSPREYPLSRARRCLGFDSLSMFHGVQSLPFHYYCASQRRGLRANVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PJD0</accession>
    <name>A0AAV4PJD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_525911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004485">
        <property type="protein sequence ID" value="GIX95262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PJD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11623" checksum="C827D6643E7A3D38" modified="2024-11-27" version="1">MHDDNNNTPLFSSQRIIHGTTIIARSITARRFLKRENDLSNYRCAITVIQMRLTPIIAWSATTLQPPPHPPSTISFSSSLLYLKGRVLENRHRSSALKEKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKE5</accession>
    <name>A0AAV4PKE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_659511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004549">
        <property type="protein sequence ID" value="GIX95667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="328" mass="37919" checksum="5E3F8A9B9F08772C" modified="2024-11-27" version="1">MTLEREYVNNNNTTNQITNRNESRGCNTSITSTKECRNYVSSLTGFTNIIKTQAVYQQVFVDIDINAKNVARDAKENLLREEEGSLDYEEPEPSYSEINDPESDDNVNQNSLTSNNVWYEHKLYDTSKERISRQDEKYVETGNHTSQWTGRRELSGCNASISSRRVWRGWRQLSVTRSEQRVNDLSAITGHHCFMDFIFPFYSDISDEEQSNADTQIAEEDIQVNFSDISDEENAADRLNDVDQNNQCNSAQHATNNQKSCGRWYYHYSLNPNNVYHDYNNENCSAWYGHTSYYKTNEDNGRQEASDKINAVNLSRDAEDDVSIKENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTN2</accession>
    <name>A0AAV4PTN2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_33691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005007">
        <property type="protein sequence ID" value="GIX99134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTN2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10317" checksum="45161001F747C188" modified="2024-11-27" version="1">MEGVYSYADNSPVPACHQCWFRHCADLLLLHFFLRLLCRKEEERKDREKPEEDTEDKNERTIEDPRDIIMKILRNFECSTEDIARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0S4</accession>
    <name>A0AAV4Q0S4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">GtrA-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">X975_02444</name>
        <name evidence="11" type="ORF">CEXT_220331</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005364">
        <property type="protein sequence ID" value="GIY01736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026218">
        <property type="entry name" value="HRG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31525">
        <property type="entry name" value="HEME TRANSPORTER HRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31525:SF1">
        <property type="entry name" value="HEME TRANSPORTER HRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="9" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY01736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17296" checksum="495C22389BA04B9F" modified="2024-11-27" version="1">MEGRERRCLLVKIVFGILGIISGISIFVSFLHYKNYSAAIWGLLSAIFASINLNLHVIYRRGALHLKHTPESLRVVKLSGVILSIAALIAAAIYFILVGVYHEGYKIDGFAPAGIFALLTLKWTVQLYFTGKKYEKFLRTSPGEMPAKGPYQSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q314</accession>
    <name>A0AAV4Q314_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_566591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005656">
        <property type="protein sequence ID" value="GIY04033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q314"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="16679" checksum="39AC3047FE735829" modified="2024-11-27" version="1">MPHIHRGINIYQVLKTLRGRAEYENLFAHFRFRKLLSSFLHSPFPIFFYPIFLCTLRILTRFHTHHMGIKGKNSQEYFKRENHKVQKNTFPKTQWHILRPQFRTVGSLQHSEAKGYIVFSHETGRPRGCLRVIIFLSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q460</accession>
    <name>A0AAV4Q460_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isocitrate dehydrogenase [NAD] subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">IDH3G</name>
        <name evidence="8" type="ORF">CEXT_121181</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005559">
        <property type="protein sequence ID" value="GIY03254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q460"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000001">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF60">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="7">
        <location>
            <begin position="56"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY03254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="389" mass="43098" checksum="7999B6D28D658FD5" modified="2024-11-27" version="1">MLASRFSPRRLMIKSKEICPALFGNRKFYKLSGGQARAISMGNVDQFKAKYGGRFMVTMLPGDGIGPEMMGHVKEIFRLGGVPVDFEEVHLDSTVQNIDNVDEAITSIKRNGVAIKGNIETRSNSPLFKSRNVILRLELDLFVNVLHCKSQPGIRTRHKNIDIVLIRQNTEGEYSCLEHESSKGIVESIKVVTREKSEQIARFAFDYAIRNNRKKVTAVHKANIMKLADGLFLNTCAEISKEYPRIEFDNMIIDNCSMQLVSNPHQFDVLLLPNLYGNILNNIACGLVGGPGITSGKNFGQEYALFETGSRNTGKGIAGKNIANPVAMLNASVDLLEFLGLFKHAKIISDAIYQTVNVDKIHTPDLGGSAKTTDVIQNVLDIVLDKTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHQ8</accession>
    <name>A0AAV4QHQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_251311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006011">
        <property type="protein sequence ID" value="GIY06888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043831349" evidence="1">
        <location>
            <begin position="19"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="214" mass="23701" checksum="25D0F3F3A1B18E7C" modified="2024-11-27" version="1">MVLILLAILSSCCVVSEANETVSELAPSGIQKCRDVVPECECNDSKTILELHCWNVSDFEKFNEKLNKRNTLYTIYLHKDSFLPRGFLRGLNVFGLVVDDPHFQGLDEKAFEGVVELEHFFVLNSSATSADIPEGAQPARPARAPGHLLLQQLHRVRRARRIPGYRGSDALQHLSQPADVPPTRLVQIMDEASYGGALSQPTAACRPALLQNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQZ5</accession>
    <name>A0AAV4QQZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_455571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006536">
        <property type="protein sequence ID" value="GIY10511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11717" checksum="5E1EA20454FA4FD7" modified="2024-11-27" version="1">MLNVESNVERSTISRHVSSPHQQYRIACHRFSKLIVTIIYTFQSSEGYRYCLTIIDWPTVTHVSQKQKPYQKVNLQSDNKDSKDLPYFECQPYYLPDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QT61</accession>
    <name>A0AAV4QT61_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_179191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006794">
        <property type="protein sequence ID" value="GIY12442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QT61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY12442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14620" checksum="999125FA98F9C091" modified="2024-11-27" version="1">MIWVRYSLELLNIHVQFCFISDSTILSEPSDHRCLTNVGLLIKPTNLQLQCYECADYFASSQDLRNHLAVHKKFALQLATLLTIPSSRRKRRRKIRRSSNDDAQSDGEMQVDQAQSGTHLSPFSRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1A2</accession>
    <name>A0AAV4R1A2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_353361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007043">
        <property type="protein sequence ID" value="GIY14066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1A2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10921" checksum="DED14EB8E0EE1FA0" modified="2024-11-27" version="1">MPNLHSQRHFYVQVPYCRCKAGGCLPCFMALGDRETATVVNGVQPRVLRVTQTLMKSIRCFWTKSISRPFYGAACKFRRDSIKPLLCAFLAFCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFG1</accession>
    <name>A0AAV4RFG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_139493_1</name>
        <name evidence="1" type="ORF">CEXT_403551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007919">
        <property type="protein sequence ID" value="GIY20689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12538" checksum="308BD5A78126F787" modified="2024-11-27" version="1">MIPRIITSASFISGASAKQLNSGKLPMKPIYPKPSYSFSKSSGLSIVQPAALLNGKQFVVEPATSRNVTTQVGETTYLHCIVDKLEDKTVGGLQRQVKQHVPRELDPLLCPINLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RL96</accession>
    <name>A0AAV4RL96_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleolar GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Gtpbp4</name>
        <name evidence="4" type="ORF">CEXT_385371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008106">
        <property type="protein sequence ID" value="GIY22132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RL96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="169"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY22132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="35844" checksum="827C54895C5DEB9A" modified="2024-11-27" version="1">MTHYNFKNIVVVPTAKELNDIVLSKTQRKTPTVVHKQYKITRIRQFYMRKVKFTQQNYHDKLTKLLTDFPKLEDIHPFFADISNVLYCRDHYKIALGQLNTARHLIDNEAKECCRHLKYGDSLYRCKSRKRVALGKMAKIITRQNESLKYLEEVRQHMSRLPSIDPNTRTLLICGFPNVGKSSFINKITRAEVEVQSWAFTTKSLYVGHTDYKYLRWQVIDTPGILDHPIEDRNTIEMLAITALAHLRACVIFVIDPSEQCNYSVEEQVDLFNNIKPLFANKPTVLAANKMDVLKLTELPEEKQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTY2</accession>
    <name>A0AAV4RTY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OTU domain-containing protein 7B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">OTUD7B_1</name>
        <name evidence="1" type="ORF">CEXT_339921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008292">
        <property type="protein sequence ID" value="GIY23577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15193" checksum="3F463E7EC26E267C" modified="2024-11-27" version="1">MDVILSEFVAHTSADPGLATDLLEAHEWNLHSALSAYYVMKGILPGEVPPSDAEITASHYKSHTINQKKETIARKQKLTRGISRATDNFTLVSQARKELAEDFDSAEQCIRPSSLKLELPEHSFFFCPTSLSFLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV49</accession>
    <name>A0AAV4RV49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_492821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008563">
        <property type="protein sequence ID" value="GIY25605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11160" checksum="4EA1E3FC5884CADD" modified="2024-11-27" version="1">MFFRLFEIEVGMKSRCHLRPNLGFHNKLTLKETNKTKTRIKCSAKNSLKAATLFWPLFCASELLKEIALMHKTKDEEEEALLLNNFLQSLLRFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVZ5</accession>
    <name>A0AAV4RVZ5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multiple inositol polyphosphate phosphatase 1</fullName>
            <ecNumber evidence="4">3.1.3.62</ecNumber>
            <ecNumber evidence="3">3.1.3.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2,3-bisphosphoglycerate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CEXT_303621</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27381"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58248"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="3.1.3.80"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:27382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family. MINPP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.62" evidence="4"/>
    <dbReference type="EC" id="3.1.3.80" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01008511">
        <property type="protein sequence ID" value="GIY25289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034417">
        <property type="term" value="F:bisphosphoglycerate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052745">
        <property type="term" value="F:inositol phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000014">
        <property type="entry name" value="Multiple inositol polyphosphate phosphatase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF8">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY25289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="924" mass="106063" checksum="AE79D9D1BB0AD155" modified="2024-11-27" version="1">MHKSTKCGLIFWALLVGVIVTILLVNLNSIRPTAELPSCVKLDGSATCHFTDPSPYRYYGTKTSYHIVAGNETESDLEIGECKPIAFYLLSRHATRYPDKEYIEGMIKLLPSLREKILNNSLSGKAKLCHEDIEKLKRWKLNMKVDDDKSLSSTGKAEAEILARHLKEKFPSILNDTYSSEKFTIEYTSRKRTRVTAESFAKGLFDKDSKKIDFDGKENDKILNFHKSCKKLRDPSYDTSEVDKFDNGALMKKVVDSVSQRVGVTLTKDDIKLIYTSCVFDYALNNSDAWCSLFSSDDLQVLEFSADIDDYYSDAYGNEVNYKQACPVAKYIFDFMKKSTENSNDTKVVLHFSHAGAIKKVYALFGLYQDELPLTADAFCSEKNRKWRSSYIVPFNSNIVFVLYQCGQEYKVATLHNEKPVRINGCEHKLCSFTKFSSTYEPISKDCNVNEICCTCCIKAFYRKKLPIALKRSNMKNWVLAAIVISLVKSNTIKGDGDIKSCLKLDRSETCHSTNPFPYRYYGSRTSYHIATENQTESDLDVGECKPVMFYFLSRHATRYPDKETIEGMMKSLPSLKEKIINNYLAGKAKMCNEDIENLKKWKLKMKPEDEKILGATGEVEAENLGRRLKEKFSWILNDKYSPEKFIIEYTSKNRTRDTAESFAKGLFGDDYKNIDFEGKTNDKLLTFYKYCKTLLKKCNNFEYDKTEIKKFDKGPLMKEVVKSVSQRIGVTLTNEDVKLIHNACMFEYALDYGDPWCSLFTNEELEVLEFGGDIYDYYTQSYGRKVNTKQACPVLKNILDMMKSTTKTNPKVVLQFSHWSALTKVYAMLGLNQDELPLKADAFCSQKNRKWRSSFIAPFNSNIAFVLYKCTEEHKVAVYQNEKAMKINGCKHKLCTFKEFFLAYQPISEECNIDKICCPCCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBZ0</accession>
    <name>A0AAV4SBZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Zfyve19</name>
        <name evidence="2" type="ORF">CEXT_652191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009279">
        <property type="protein sequence ID" value="GIY30809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032154">
        <property type="term" value="C:cleavage furrow"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009838">
        <property type="term" value="P:abscission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044878">
        <property type="term" value="P:mitotic cytokinesis checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19817">
        <property type="entry name" value="Bbox1_ANCHR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044553">
        <property type="entry name" value="Bbox1_ANCHR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603">
        <property type="entry name" value="ABSCISSION/NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603:SF1">
        <property type="entry name" value="ABSCISSION_NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="253" mass="28782" checksum="F11A501466B18461" modified="2024-11-27" version="1">MYLATLPSESEIEERLAKLKGMDPSKYTAPPIQVFRPSEKLTSVEQASNLITQITEEVVLDSRRIKPEDEIATRLARLRDEPPPPPKFEEFNIPPSLVAGSSEEMSMNEEYINFHDEAKNLSELACKEVKELNTNADYKKLLSSMQQEKGAESENEEAEADKLVEKLLATQLSQDDIEEMDGVNDLDTEKSKNQESMDEELPWCVICSEDARIRCFGCEGDLYCMRCFKECHDSLDIKDHKTCPYLPPKVPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SD61</accession>
    <name>A0AAV4SD61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_765041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009477">
        <property type="protein sequence ID" value="GIY32233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SD61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12337" checksum="02A2677735DE3BBF" modified="2024-11-27" version="1">MNLTVDMTFKSSKYSFGCGAFQGIPTNSEVKELPIRAPSYSHMSEYESGDLGVPELPKEKEDREKDFSVVTWTSSTINSLEVTLNLFWMILMRRLEERMNFHHWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SF55</accession>
    <name>A0AAV4SF55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_231781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009426">
        <property type="protein sequence ID" value="GIY31831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SF55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043943720" evidence="2">
        <location>
            <begin position="24"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY31831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17547" checksum="B75C689E4E7D9156" modified="2024-11-27" version="1">MSCAWRLMSLLFWERTFSGLCCASDDIEGNDLFRYPKSEPASPTSPEMLSNLTNEERCATVSCILMKKDIAQSLLDTFNATTFGHALDEDDHVKLKTLEQDLINALREVGNLELCPLIDCKKHKANVNNSSVNLKSNASHITTVNHDNADGFSKPPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SG55</accession>
    <name>A0AAV4SG55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_716861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009574">
        <property type="protein sequence ID" value="GIY32989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SG55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9583" checksum="0A5156307E1D0FF2" modified="2024-11-27" version="1">MATFPRSSIKRLYNQIQARLRKHFKIHNDNTWENKLASLTTEDNSLWRTTSSFKKKRTKIPALTNVNLPTNKALTDEHKADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SH66</accession>
    <name>A0AAV4SH66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_347651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009521">
        <property type="protein sequence ID" value="GIY32511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SH66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11113" checksum="8CE84A1D33813C92" modified="2024-11-27" version="1">MVCRPSSSDRTQTAVGRSFGAVFSVREKVGDRAELCACGQYAAIYAPGESDFIHYKRPLTHSFIFLYSVFVFVLNISLGTSLESHFFPSSLAHSITGRKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHN5</accession>
    <name>A0AAV4SHN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Transcriptional repressor CTCF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CTCF_0</name>
        <name evidence="13" type="ORF">CEXT_296051</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009444">
        <property type="protein sequence ID" value="GIY32015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:004176">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000373">
        <property type="entry name" value="Putative transcriptional repressor ctcf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002321">
        <property type="entry name" value="Putative transcriptional repressor ctcf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001668">
        <property type="entry name" value="transcriptional repressor CTCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002963">
        <property type="entry name" value="Transcriptional repressor CTCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000049">
        <property type="entry name" value="transcriptional repressor CTCF isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001732">
        <property type="entry name" value="Zgc:162936"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056438">
        <property type="entry name" value="Znf-C2H2_CTCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF81">
        <property type="entry name" value="CCCTC-BINDING FACTOR LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23611">
        <property type="entry name" value="zf-C2H2_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="457"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="514"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="542"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="571"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="600"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="628"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="656"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="857"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="859"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="888"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="930"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY32015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1039" mass="114604" checksum="A528AD4D56C589E6" modified="2024-11-27" version="1">MALIATKNAWRCMDDHANEPEGAETITDIQNYLASFNKEIQDGGTSGTSTTATALDATAEGTATEANTETAFFVAAPGTTSAEGFQFEQAEAPFGTTYYTSSDGTYYATTTGDPNQSSTLAFATQADGTAVLPVTGQRTAYRTVNTGDHAGLQQIVLAVSEANSAAGNSGGRQEIVAIPASLTPQAISNTAGVGDQQAFVTMQTSSHDSQIEEAQTVQNEGQLATLVTTEDGTPVDSKAALTQVQTIRMILRNADGTETEQNVPVSSSRVPTLVTNDGQEVSLSDENQLQMISTIVEQAASAGGLADGNNQLILNVGNTYQAVTVVPTNGAGGDVSYMFIVAQSDEDKDPNKEIDLDMSVYDFNEGEKHGEIVAEEVAADGTKTRTIRITQKKSQIVTQAHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCGVCERGFKTLASLQNHVNTHTGTRPHCCRDCESSFTTSGELVRHVRYRHTHEKPHRCTECDYASVELSKLKRHMRCHTGERPYQCPHCTYASPDMYKLKRHLRIHTGEKPYECDVCQARFTQSNSLKAHKLIHSGNKPSFHCDFCPTTCGRKTDLRIHMQKLHTSDKPLKCKRCGKTFPDRYSYKLHSKTHEGEKCFKCDLCPYASISQRHLESHMLIHTDQKPFRCDECDQAFRQKQLLRRHKNLYHDPNYVAPAPKEKTNECSECGKAFLLSKKFSEVYWTIKQGFVQKGNLIRHLAIHDPEASMAEKELALRIGEPKGPGETPDGEEEEVYYMEEEEEDADAPPFSGAVTIAEQGTVQQTEDGQQVVVFEVIQLHPPDGDQSVEELQPAINSNGETSILPTVHESPEEEDCFASAVAEAIGEAISTPASPATPATPRKRGRPKKTPVTSSANELLKHIKAEEIKEEAIKEPNRMGRKRKVEVIEPQQEISLETPKTRGRPVRSCRIRKDDSNAGPDIPTAVISTPIVCDEMDDTPVTEELARREAEQERRRLEQKQKDMEECFGFNEDEEETETILAMPAVPGAQSMSLMDDSTLLGSLSNHNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIU4</accession>
    <name>A0AAV4SIU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized urease accessory protein ureG-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SPCPB16A4.05c</name>
        <name evidence="7" type="ORF">CEXT_26641</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009422">
        <property type="protein sequence ID" value="GIY31743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715:SF0">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY31743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="10757" checksum="D6C248A13C18FCC1" modified="2024-11-27" version="1">MVFLESGGDNLAANFSRDLADYIIYVIDVAGGPGIIESDLLVINKCDLASAVGASLEVMKSDANVMRQNGPTVFIQAKHMVGVDDVAQYILDAYKKACKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKZ1</accession>
    <name>A0AAV4SKZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_541231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009595">
        <property type="protein sequence ID" value="GIY33140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10941" checksum="6CBBFE9F5A83F6E2" modified="2024-11-27" version="1">MPKVAALIAALHANTHYQRKRSRGKKKKQLLFRNDFGLAREGHWHPIRCGPNTLWAGNRSHLARKRMDRRHRFARETIGPRQYFMASKDHLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXC3</accession>
    <name>A0AAV4SXC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_460731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010127">
        <property type="protein sequence ID" value="GIY37145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="8043" checksum="7B8D7C30DA14AE3A" modified="2024-11-27" version="1">MRSEPLTSSIFEICIRKKKKVPEEKNGNGDDDEIEEKKKRLSEREHHHDEMSLNLWKGFKRIDEFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T136</accession>
    <name>A0AAV4T136_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tudor domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TDRD5_3</name>
        <name evidence="8" type="ORF">CEXT_502322</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010383">
        <property type="protein sequence ID" value="GIY38981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T136"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08824">
        <property type="entry name" value="LOTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16442">
        <property type="entry name" value="RING FINGER PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16442:SF1">
        <property type="entry name" value="RING FINGER PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0221">Differentiation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0744">Spermatogenesis</keyword>
    <feature type="domain" description="HTH OST-type" evidence="7">
        <location>
            <begin position="293"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="6">
        <location>
            <begin position="550"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY38981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1021" mass="116499" checksum="059D11093A3DD794" modified="2024-11-27" version="1">MIGRNIPYANFGYTSTVRFLSDLSDVVRINRSGNDYHLMCVADENTKHIVQMVAKQKAPKHKPTTRPKTTRYVYTNSVEKQRPSRFQRSSAPSNKVLPSSIETEIDHGFYTLQECLESISSIILKPLDNDVLIQYSSAPEETYFVTVDQNTNSRKTFKSTSLPLANTTQSTFDQSRQISNNYTDKCASTASSKLSHFNTPTRASSVRNSEEPFFHDQDSDPTYEHFKPNSYNYCDSTAVNLSSRDKSPLLDNSGISLSKFRFNGNEKVQNLQDLNLNANNSGLCKKNVNESHVSEKIKDNLRKIIGTYRHGIWAKEFPAIYQEITNTEFDLHSLRFYDMASFVDAVPDILARKSIVGSKKDWIILPADKVDEFDVSNPKSASLMIESIIASTRKILQAYPEGIPLSEFLHAYCLNCTEPLLLEELGFDCIEHLLICIEDRVPLEIKKIEGGKLVCFLQSQKKFSPSPPKHESLPEKAVSPFSVYVQQAIPDNLNYQHSSISVYIAEVNDPNHFYFQIIGPTTSDTLKSLYDDMETFYNKYEHKYRMNFKHINIGIRCVAKWPKDCLWYRVRVIALPSPEVVKVIYVDYGTVSDLKYSDLRVPLALKGSLVDIEPPNNNVSWSIQASNRFLKMISDISLVAFVTDIVNDVYYMRLWNTNSTNNININISSVLVKEGLAKNKPLHPESNTQTATATAPTPTASNDENKTVVTFFEKLVEAWKVNATQKSENLPTILLEQLTEVIQTSMNQQQSAISPPVENLVETASPSNSDSSPIDIDSDGEIFDADDDAFFEELYQNTVTRQYIKSIRTKDWYEFNVLIYQNELFISGGDIAGLIWSDKDSDYFLQRVQNREVDFKFINVTENENLELFRQVKKSFSSVKGLKKVMDKECLVIAPLKTLIPILNLFGHPSLELRLMIRKIIKDFSPFLCAWMGTSSRETEDIEAGGRPETDDDKVNRLNLCELQTMKVGICLRRSKLKEDDVEEMERLRLLYDIVLDRIAEAAVICFLLMYIMNLERYFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1H8</accession>
    <name>A0AAV4T1H8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_682571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010407">
        <property type="protein sequence ID" value="GIY39114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1H8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12062" checksum="0A61F5B77685F75D" modified="2024-11-27" version="1">MGKEEEKEKEKKYVKSELPKEISAQCLTLAFCPRAICRRSLIPGNVYFIFHVQILLSVEQRNPLKRCLLSRCSELVNFSRTPVEISFSLFLICFFFSSSRVLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBR7</accession>
    <name>A0AAV4TBR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_608331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010909">
        <property type="protein sequence ID" value="GIY42906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11946" checksum="5B582DA869D2555D" modified="2024-11-27" version="1">MAIPLEMFNKMPKIGWKGTRTVIYESTSNTQCQASSYIPELESSALAAEWYCRIRATTATTLFYLYETLVHDFGSTLRIVDNPPLQVFSFTKLFVAEACENLFCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDI4</accession>
    <name>A0AAV4TDI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ecdysone-induced protein 74EF isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Eip74EF</name>
        <name evidence="10" type="ORF">CEXT_331681</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ETS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011171">
        <property type="protein sequence ID" value="GIY44623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040034">
        <property type="term" value="P:regulation of development, heterochronic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000411">
        <property type="entry name" value="Ecdysone-induced protein 74EF isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046328">
        <property type="entry name" value="ETS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849:SF191">
        <property type="entry name" value="ECDYSONE-INDUCED PROTEIN 74EF ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00178">
        <property type="entry name" value="Ets"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00454">
        <property type="entry name" value="ETSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00413">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00345">
        <property type="entry name" value="ETS_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00346">
        <property type="entry name" value="ETS_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043461621" evidence="8">
        <location>
            <begin position="19"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="ETS" evidence="9">
        <location>
            <begin position="274"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="36"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY44623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="41722" checksum="966348A1C2BF86CA" modified="2024-11-27" version="1">MLEFSVLMHLSLKSFIFCFYLDPNSIPVSVFPGQTQSQYRHHRTNIHQHHQQQQQQQQQQQQQQQHHQQPQLQPPHHNSYLDASRSQKSHATYNNLSSASNHHASHHLGHSLHTSSISQLQAHLSGHHLHSPVSHLGHSLHTTSISQLQAHLSGHHTHTQVSSTTHGAPISPLPLALTRNNNSSCPSSSPNTGIPSSSGLQSPIGGVHQPAIPTSVITATHNSPCGLDIDPASYVEDLSYQARIKKKVFFLLRKPKNPDGSPAVKRKSREGSTTYLWEFLLKLLQDKEYCPRYIKWTHREKGIFKLVDSKAVSKLWGLHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIVEIDCTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEZ9</accession>
    <name>A0AAV4TEZ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_598511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011031">
        <property type="protein sequence ID" value="GIY43779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="19245" checksum="F42D71D156A7F1C2" modified="2024-11-27" version="1">MPSDFRYTCNICKGSSILTPNTNDAIICKCVTTEKHCISSQRALPRRVVRKPQKLTKESRIRSLPFSIKHYKCVPWENIYHNGTYFRVGDIVAYKRNNKYRLARLRGLLINNSFEKAAFIGRISEIGQNKNTILINEKEENILKIWRISSLFAMTNFVLKIMKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJ87</accession>
    <name>A0AAV4TJ87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_281881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011464">
        <property type="protein sequence ID" value="GIY46688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJ87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="216" mass="24871" checksum="8E9A89059BAAFF9E" modified="2024-11-27" version="1">MRPKETFSPEKLPKQCELEEKNRVLEKSIEALSVFILFQAFQSPLNGRRGRGAVNRDQSHQTSKNQIKTSNSSNIKRSESSNIKTSNSSNIKTSNSSNIKTSDSSNIKRSESSIIKTSNSSNIRHPTRQSSRHPTRQNKFRVLNHQDIQLVKHQDIRLVQHKEIRVLNHQDIQLVKHQDIRLVNIKRSESSIIKTSNSSNIRHPTRQTSRHPTRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMR6</accession>
    <name>A0AAV4TMR6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_790241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011354">
        <property type="protein sequence ID" value="GIY46032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047153">
        <property type="entry name" value="TRIM45/56/19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462">
        <property type="entry name" value="BONUS, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462:SF291">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="2">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY46032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12592" checksum="1904678D972846C7" modified="2024-11-27" version="1">MHCFEGHNVIDLKDELLNGATQDKLLHCPRHDREIIRYFCRTCNVPICKECATEHPTGLHDYDHISDVGPREIEMLRLQIERCKTKLNEFKSAGSSVDSLLNCLEEQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQC6</accession>
    <name>A0AAV4TQC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_260197_1</name>
        <name evidence="3" type="ORF">CEXT_612001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011704">
        <property type="protein sequence ID" value="GIY48340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY48340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="420" mass="48171" checksum="B77DF27507F59E67" modified="2024-11-27" version="1">MSEASKSHLESINETKEHEESATVESFDTDDSNLVHTTAQNTSSVIENELKENNDRVKKEYLQPPDSATLQTDSNQLPQESETETSDAEFDSDGQPDPISKLPHLMTNTHQEKFSDEKYVNSFEDEGNSNLKAQSEFPNNAHERIQESEFPNYVLERIQKSEFPNNVREQITESEFDTSNNNSSLSMDEGRELNSEMSYVHAQNQKQRESADCGILECLEDNDLADSKDYDGDLITPVIEDEEDDYKIDNIRSASNQSESSLNSTLLRNFTEHANNQSAFEYVENIGFNVREVIHIIKTDSNVRAYILNNIILYLPVLICDILLWMVTVKLIRHIRRQIIVKQEASAERPKDQQDKEEDSVDKIPQLKSLIKSKRLGKIATMNIKIVALNFHSWILIKKFGILQVKIANFIFRNLNFVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWT8</accession>
    <name>A0AAV4TWT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_318641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011842">
        <property type="protein sequence ID" value="GIY49487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12953" checksum="BB89827AD0341662" modified="2024-11-27" version="1">MHSSFDALPVAEIGGRIFAIGNRMAEFLNLFRGPLAERSGRLFHSLSETLKRLTPKNEFLIIFESIIDHIMKLEWTTMVDRKRPVGKIRRSPILPIPTATVSAPKALNPGHHGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYQ7</accession>
    <name>A0AAV4TYQ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytoplasmic dynein 1 intermediate chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sw</name>
        <name evidence="7" type="ORF">CEXT_242512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011981">
        <property type="protein sequence ID" value="GIY50469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYQ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="609"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="610"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY50469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="631" mass="70693" checksum="ACE8B553742A4B1C" modified="2024-11-27" version="1">MEEFLVKKDGMADRRAELERKRQKLALLREEKARRKREKEALKSEEAAIISLKREKDVLVETDKLLASLNVTTSIASLPNTSDSSLSDVSLNKSIPPQPSPPKPKISKINLSVVNVHQTTVPPVEKIVYDKQSQTIHSSGGDKEAASLDYYVLTYDDSSISEEGESLSLQSIDGMVQHFPSQKHHKLIGLPNVNMVKPAKTLADENKLAEEKQKEEEKINSFSILASDLSDEEKLQLMRTENFKHFINRSSRIIEELSSKIDDHSGMSLSLNRCFADDHWSKNRTVTSFDWSTQFPELLCASYNQNEEAPHQPDGICLVWNTRFKKTTPEFVFHCQSLEGLILVKMVLWDNRSNKRTPVQRSPLSAIAHTHPVYSICMVGSENAHNLVTISTDGKCCTWSVDMLSAPQDTIELNQQKQSRTVAVTCMAFPNDEFNNFVVGSEDGIVYSACRHDSKSGIIESFESHQGPITAISTHKSRGPVDFPDLFLTKSQPLYSFEHNSDYVFDVSWSPIHPALFACVDGLGNLDIWNLNCDTELPTVGTQIDGCPALNRVSWTHSGQQVAVGDSMGKIWLYDVGEQLANAKADDWPKLMETLEEFQSNQSYMSGEILSPQPSQVSLPQSPYLTSTPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2T6</accession>
    <name>A0AAV4U2T6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosine-protein kinase Fer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FER</name>
        <name evidence="5" type="ORF">CEXT_266541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012190">
        <property type="protein sequence ID" value="GIY52057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2T6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10361">
        <property type="entry name" value="SH2_Fps_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000051">
        <property type="entry name" value="Tyrosine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035849">
        <property type="entry name" value="Fes/Fps/Fer_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050198">
        <property type="entry name" value="Non-receptor_tyrosine_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24418">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SH2" evidence="4">
        <location>
            <begin position="50"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY52057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="230" mass="26769" checksum="84ACAE92DD94069E" modified="2024-11-27" version="1">MNTYPVLVNFKALPEYSRYLRVNLFYSLTNPGHDNVVLNPSYTSLQDEDWFHGVLPREEVVRLLEKEGDYLVRETYRNNSKQIVLSVCWEGHKHFIIQTTTDENSDLKVQLSHLSKELILYQFHSGQPVTSRSGAVLKTPIIRERWELNNDDVELVEKIGERVSSSSTSSNDINQSITYHLSELTLSLEKLQVVGYEDDCNQHWKEVRYHSPTKKLCRIPLQWSICIPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U748</accession>
    <name>A0AAV4U748_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_629381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012381">
        <property type="protein sequence ID" value="GIY53633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U748"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="372" mass="40669" checksum="BDDAAA5113417D44" modified="2024-11-27" version="1">MSAHDENSYTSYTSASENIGSEDTPEELRGDELTSSSTTATTSSSASSPRRSPRLAEKRSRILEKEGVTFRQKRRRHGTGPPHMIIVPVASLPHPRAAGPPVPGGLFTHSPPHVPTVRILVWPSPPPTSWSPASGASSPPKPSSEPVWQPRYFDGCPESFATSLQGLKFLEPGQTFQHRCPGGRQPGEVPHHHHPLHFSLNILQTRQIWRDLFGRNSPSLPSSGGSSPASPPSHHRLPDEPPDPADFIHISSLPLLQSHHQLQQAPPPPPPPQHQPPQHHLHQPPQHQPPPPPPPPTAAPPPPPLGQSPDPKQDLFERLLPPRDVWKRPVMRPELRSGSRKPGNFPMQRPETSADGKRQPMSASSARIPGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFM9</accession>
    <name>A0AAV4UFM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein quiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_179470_1</name>
        <name evidence="5" type="ORF">CEXT_736852</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012785">
        <property type="protein sequence ID" value="GIY56612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032222">
        <property type="term" value="P:regulation of synaptic transmission, cholinergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030431">
        <property type="term" value="P:sleep"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23589">
        <property type="entry name" value="TFP_LU_ECD_Rtv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031424">
        <property type="entry name" value="QVR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050975">
        <property type="entry name" value="Sleep_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562">
        <property type="entry name" value="ATILLA, ISOFORM B-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562:SF22">
        <property type="entry name" value="PROTEIN QUIVER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17064">
        <property type="entry name" value="QVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043966244" evidence="4">
        <location>
            <begin position="24"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY56612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16064" checksum="6297825AF8A7DF9C" modified="2024-11-27" version="1">MYRATCSILFLTILAGLLSLAEQSRIKRCFNCRSRGDLGDCKDPFPHNASTVEEMRAVEATPCASGWCAKIVEGKGDDYAIATERMCLQRPPGDEEQRCAPTLFQGRRVMMCFCKGDLCNSAMTVQAINICVLLSILGIILKFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UI32</accession>
    <name>A0AAV4UI32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_326361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012906">
        <property type="protein sequence ID" value="GIY57428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UI32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11558" checksum="110FD97A08C2B386" modified="2024-11-27" version="1">MFKGNWGIQIGNVPGSRASSNESSTPTPFDQMIPRKRMEKTRSDSRSYHSPGGAALRRSGSVIGRTVADADDSRDTRVESVHKNPLSSEFECCITIRMPGERCGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTU8</accession>
    <name>A0AAV4UTU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_290541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013433">
        <property type="protein sequence ID" value="GIY61139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UTU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7545" checksum="25D5181788123DD8" modified="2024-11-27" version="1">MPHQECFGMKHTKEGNIMGDVTYIGTPQGSQGIICTIREDHTVEKRKPWDTASRTSFPCDTTEDAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2Q7</accession>
    <name>A0AAV4V2Q7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_657151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013834">
        <property type="protein sequence ID" value="GIY64113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2Q7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12668" checksum="6ED17BE4C9738FAF" modified="2024-11-27" version="1">MAEQKHKTHCKNSNVVIWCRYINTARRRISKQILHNVCGEGKIPSYLANATSCRIYIAAPGDDVGILQWVLCFCSAINPDSKTKKVEMSRWLLSSPELNSVARWCSHFEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V374</accession>
    <name>A0AAV4V374_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proline dehydrogenase</fullName>
            <ecNumber evidence="5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">slgA</name>
        <name evidence="7" type="ORF">CEXT_612931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01013838">
        <property type="protein sequence ID" value="GIY64144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V374"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY64144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="346" mass="40554" checksum="7C1BBEFA2B35E3B8" modified="2024-11-27" version="1">MGELKQYQPYEEFADRRKYHSVARTYFYLDEAQCEKNMETFLKCINAVAGSTQSTGFAAIKMTALGRPQLLMQLSEVIAQTRKFFCCVTGEEKRIALLNMTPEVLEHKLEDYNINTGEKDVKEFLQHMDYDKKGLMNLFCWSGLVDMKYVISDLFKVPNIKTGTIEPIISALTEEEEEMFRNMMRRLHHIAKVAREKDVRVMIDAEQSYFQPAISRITMELMRKYNKEKAIIFNTYQCYLKEAYNNIVLDLNWQTDKIFTLGPNLSEELTWNKRVFEPRRLATRIPSTPATRLPVTCTTESSRRFCTASSKKVIGKLPSWWRLTTRILFDSQSTRWRRWALSPSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8D0</accession>
    <name>A0AAV4V8D0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WxxW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_692631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014096">
        <property type="protein sequence ID" value="GIY66215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8D0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025155">
        <property type="entry name" value="WxxW_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13330">
        <property type="entry name" value="Mucin2_WxxW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="WxxW" evidence="5">
        <location>
            <begin position="12"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY66215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="6987" checksum="8D9DEBBF0D7174E0" modified="2024-11-27" version="1">MGLSEGGCSFSETMEEIVAKSGGCDDVKGIECRSVTQTSDGSVRQQVVCNILDGFVCRGEDQPPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDK1</accession>
    <name>A0AAV4VDK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_623031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014325">
        <property type="protein sequence ID" value="GIY68094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15008" checksum="DB767466F1DB3FB1" modified="2024-11-27" version="1">MPTPSLRRQCSKCIPGHLCACRHGGPHGERHHADDRDEEVAHQFRLRRFLVSPTALVTGPAATATPHGDVACLEQHSVHCRGIFDLSWFFFCPRPKGRTRKTWEAVLHFVQELLWQLSSFCEDIDVSSISFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHP7</accession>
    <name>A0AAV4VHP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_583781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014570">
        <property type="protein sequence ID" value="GIY69687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY69687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="14880" checksum="5746D45FCD267FAB" modified="2024-11-27" version="1">MVPPCLKESFGSTDNVQRKKSARDATGFPEGDGPIFSELHLHVSRLYEFLRPFLLLEENLALNGATGMDLKQRSLPLLMLRETGKKMLPLIFLQTASAFRSRIFLYTYALESMLWFGLIQVLRNSKMNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VID6</accession>
    <name>A0AAV4VID6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Abl interactor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Abi2</name>
        <name evidence="15" type="ORF">CEXT_546871</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Filopodium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Lamellipodium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014554">
        <property type="protein sequence ID" value="GIY69599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VID6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030175">
        <property type="term" value="C:filopodium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030027">
        <property type="term" value="C:lamellipodium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031209">
        <property type="term" value="C:SCAR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017124">
        <property type="term" value="F:SH3 domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001764">
        <property type="term" value="P:neuron migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11826">
        <property type="entry name" value="SH3_Abi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000002">
        <property type="entry name" value="abl interactor 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028457">
        <property type="entry name" value="ABI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028455">
        <property type="entry name" value="ABI3_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012849">
        <property type="entry name" value="Abl-interactor_HHR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10460:SF0">
        <property type="entry name" value="ABELSON INTERACTING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10460">
        <property type="entry name" value="ABL INTERACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07815">
        <property type="entry name" value="Abi_HHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="14">
        <location>
            <begin position="15"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="315"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="142"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY69599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="380" mass="42130" checksum="6DC7A9B0A6A4D541" modified="2024-11-27" version="1">MLYSQLPAKAENKRLALEETKNYTTQSLASVAYQINTLAYNLLHMLDLQTSQLTEMESQINHISQTVMIHKEKIARREIGILTTNKNTTRQHKILAPANQERPIKYIRKPIDYTILDDIGHGVKSTSNTPRSKRTLAPVHQSALNGSSAGPAPTTKPPTPPQPVRAGGSLSRGTKEYRTPAPPIAPPQVPSNYAPNFPIGHPRSQEMRRGSGYSTLPMAFSSSQQSQNMLPSQPQIGMVHPMTHGHHSNTIGPSSPIPPPPDMTDKLPDFAHPGNISPPLPPPPPDDDNLYHENYHPPSPPYLRRHGVPDWVPKNYLEKVVAIYDYVADKEDELSFSENSIIYVVKKNDDGWYEGVMDGVTGLFPGNYVEPSGELTLNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJD8</accession>
    <name>A0AAV4VJD8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_244441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014639">
        <property type="protein sequence ID" value="GIY70223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035060">
        <property type="term" value="C:brahma complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071565">
        <property type="term" value="C:nBAF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16865">
        <property type="entry name" value="ARID_ARID1A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021906">
        <property type="entry name" value="BAF250/Osa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033388">
        <property type="entry name" value="BAF250_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12656">
        <property type="entry name" value="BRG-1 ASSOCIATED FACTOR 250 BAF250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12656:SF5">
        <property type="entry name" value="TRITHORAX GROUP PROTEIN OSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12031">
        <property type="entry name" value="BAF250_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="471"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="580"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1318"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="659"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="749"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="775"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="788"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="845"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="862"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="944"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="986"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1000"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY70223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1790" mass="196201" checksum="0E471C04CCD81A4C" modified="2024-11-27" version="1">MFQDGEDVVPPESAATSGALRNLTTPPHSGVSPHRPAPSPSGSSAGSPSMSPALGQQPNIPMPPRPSSTQSESSGQSQIPQPPAAAQGYNQQMAPPAMYGNKMHQNMMSGSSSHMTPYSPQSSGHYPQTGYHRPPGSMGMHNYGSQGQNNYPGPTYPSQSQMPPHRMPTHPSPAPSNYVAPPNSSGYNSSQYSNTGPPPSGYPMNNMMPPPNQYPKAASMPPPAAGAQAAAQAAVIAAAASSNPTRQSPMYLRQHLQQKLYNNYNSNIPGPNSGQDSPMPPPASTPSSQSMSQSSLPPTTGSASSCDGSLPSSMVPAGFTQAPSLGMPPTTVTQSISSPVPSAVTVSSPSVPDMMQSPQVRNSMGGPPPPPVMDEGSQASNASASSSLPEERVETPKPSNKPVMSHPPTPNTLPSPGAASMSSFHDEFESVSSPSWPRTPASPKVINNQPYDHHPIKRPDGMLKLYELSDDPDRRLFLDKLIMYQEERGTPLSQCPTISKQPLDLYRLYLACKERGGFVEVMKGKMWKEIAGLIGIGASSSAAYTLRKQYIKHLLPFECKFDRGGIDPVPLISSLESNSRKKNVKNAGGPMMDGYPGPYPGGYPPNTGPHPGMMPGSDYPGPGHHPAYQDTLHHSGSSMVNHAGSEGAMDPFSDDMQGPQYQPRHNSSDNYGYSQPNANSNMPPYSANQPSAPSSSFGYSNTSGQQEPYNDQYPNTMVPPSSEASYSNRNVVPDPYAPPPGGYPPNRTVGPSNSSQYPPYQNPCGDQERFAEPQSTPPTPMIRPPAPNSSVIGPSTQESSYPPHRYGSQPMAGRDNMPPQPMSSFQGRPSLGPSQYPNSQPPAQSPYSSAQPESYRGPEYQPQMSRLQSTLIQRLLPKNQTAQNYPSSQQGMYGQSMPPPNKVAPPSNIPSNMYQRDMYSMGPKRHGDYSKPHGPVQDQYHMGSYPQQPSQPPYSDRSQYPYRPSHGVPPQAAGLPQQGWPRDNRSYSSGQNQYPPGQRENWEMARHGENASQPGGATWSRYGGPQPEPYPHHMGPSMGPKMMSRGYGPNKMTPHGGVGPPPQYTPPSQRKEVIFPPDTVEAVAPLITKRRRLVAKDISPIDPWRIMMALKSGLLGESTWALDVLTILINDDSTILYFGLNHLQGLLEVLMDHYRRCLNLIFDLVGDMEVGFMVDPQESKQHSKKWYELDCDVEEAPSPTISNCDVLSSDKIHILDSTNYTYRTRCRKSVRTQDEQALFLFDPDKKWDVHEGFISGSSHWQHGGGEYTGYIQTQFENTEKRVRFVRVLKDVVKNKSLSKNNSCKGKSKENAYCKKECGSDTEEDESLSERSPNSVVLEKTPEEKLNGSVKKLNEKEKCTNSTENVNIPSKLVSENVERTNDSDMEVDELIESANKEEVDKNKSDEKDISNVFPKIRPVSPSRKRRALEDLEDESYTRDEPSLCTVTDAQDSLARRCIALSSILRNLSFVPGNDTEMSKHSGFLLVMGRLLLLHHVHSPRKPPQRHYDRDEEGENASIADSCSSLNSEHEWWWDMLHIIRENALVTLANIAGQLDLAPFPEEISFPILDGLMHWVTCPSSYAQDPLPTQPSNSVLSPQRLSLETLSKLSVLESNVDLMMATPPWERIDRFFSLLSKWLSRNEDQVLREFSVVLLSYLSQADSSMARAIALQGTCIPLLITFVEQAEQSALQVANSQGINALRENPELMGTTLDMVRRAAGTLRCLAKVPSNRTLFLQHQQRLLALVMSQILDQGVASIIADVLFEVSRGDDLSSLTNFEKASLSLMEETNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVY0</accession>
    <name>A0AAV4VVY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">IGFBP N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_245847_1</name>
        <name evidence="6" type="ORF">CEXT_745931</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015222">
        <property type="protein sequence ID" value="GIY74442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005520">
        <property type="term" value="F:insulin-like growth factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001558">
        <property type="term" value="P:regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000867">
        <property type="entry name" value="IGFBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011390">
        <property type="entry name" value="IGFBP_rP_mac25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14186:SF20">
        <property type="entry name" value="CYSTEINE-RICH MOTOR NEURON 1 PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14186">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00219">
        <property type="entry name" value="IGFBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00121">
        <property type="entry name" value="IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51323">
        <property type="entry name" value="IGFBP_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="IGFBP N-terminal" evidence="5">
        <location>
            <begin position="21"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY74442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="24738" checksum="ED66474D7AE852F0" modified="2024-11-27" version="1">MRSSSGKRPSLCRGILDFLSLKQRNSSWQLQEKCSLEVNKRRRLNCKGGWTLGICGCCKVCAKLEGEECGGQHNYLGKCDKGLVCEPQEPKFVSFFRNGTKTVYKNPRGICSARDNAEIFQDCQGLCQHTSCRACRFVDPFQACKKCKKDDFKCIREFGRACIRKDACKNAKRISMRKVSLQKNWKESFNAKFQHANLKTMSKSKNNDHGLTFNASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VXD1</accession>
    <name>A0AAV4VXD1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein ced-11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ced-11_1</name>
        <name evidence="1" type="ORF">CEXT_251161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015261">
        <property type="protein sequence ID" value="GIY74798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VXD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17974" checksum="19F0FB57D3AE3277" modified="2024-11-27" version="1">MNVEFGKCYFEKGSYKQYKYKEPIPDEELLSEVGTEDEVKFGRMYHGDHGWDIKHWPFILSSYTAPMNAVFSKIMLDWKLSIPRIVLFVIAGSTDSLSESIKKLEILLIKGLMAAKKDHRDVVVYRWLLSRIWKRFRPRFYKRSRANRVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W225</accession>
    <name>A0AAV4W225_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Discoidin domain-containing receptor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DDR2_1</name>
        <name evidence="2" type="ORF">CEXT_68221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015428">
        <property type="protein sequence ID" value="GIY76036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W225"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="29410" checksum="1E565E9D28F71A74" modified="2024-11-27" version="1">MQVLRRDVGGWYENKPVEVNETFTRESTSRQDFSPSHLNNGSVYGRVAADESDALPLHEPQEMKANYSGAYCNASPSPGSAFGREYAVPDFPRAVTDIQGVSGSTVYAAPHLDERSLPSVPEIPRHRLRPSRSWGRGGSERWVLSSSSAFVFAEPYQAYSIRVVAGSLVPRRGFFGAGGRPLSHPGGREECRAGESTSTREDFFNEVRVLSRLQDPNIVCVLGVCIQGEGPSAWWWSTWRRETCTSTSGNALPRKRPAPHRRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6V4</accession>
    <name>A0AAV4W6V4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SMARCC2</name>
        <name evidence="2" type="ORF">CEXT_591981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015762">
        <property type="protein sequence ID" value="GIY78501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6V4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048858">
        <property type="term" value="P:cell projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049898">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032450">
        <property type="entry name" value="SMARCC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381:SF1">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16496">
        <property type="entry name" value="SWIRM-assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52032">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14630" checksum="3DE95F5A7970F962" modified="2024-11-27" version="1">MTCYRKKDGGPNVKFYESPETITQFDTVRQWLQKNCKKYIQADPPTAKGLAALVNQLIQFQEDAFGRTVSKPPLTRLPMRCFLDFRPSGALCHILASVYKFKSEQGWRRFLISSLHLEWIVMLKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBV1</accession>
    <name>A0AAV4WBV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_398621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015990">
        <property type="protein sequence ID" value="GIY80292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7316" checksum="BB6B4DF7623ED6A5" modified="2024-11-27" version="1">MSMFCRSTAAALSKMGQSARVSRTLGDDSSQPRLGHYSSPCGAFPSGYHSGRPRLRSFRKESSSMSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFI1</accession>
    <name>A0AAV4WFI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_197903_1</name>
        <name evidence="2" type="ORF">CEXT_585791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016100">
        <property type="protein sequence ID" value="GIY81281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="435" mass="50483" checksum="21D94C1871914ABB" modified="2024-11-27" version="1">MDRTLLSIPKAGALDKYPIPAPKDLQINEFAMWKRCPTDQKHPVQKRPRKEIEFYRSKIGEQLHLRYPGKRFDQTGTVKPRIPTLTYNSLNDPYMRHYFRTLPSYKDLVDKGLVTADGKVRVDIKEFNQYRMYLHHIWTMEIDHLRSTQEMEEHKRLETLLKAVENGDSICKNIVEKQDFVNADVVMEELEKKDDILDRIKHPLVRSMLNWKYYQLRLRRLHSRYDKLREKQSKSVQPSDETPGKQAEKQRMLCEKRQNLYKKIWSKNKSELSRRSQKSRQKSLSEEDAGKSTSKDSSSSRSSTTGDTSSKDPSIEDARKSSSSSSDSTSHTPMGNYTWEDESDNTRNTFNTSDNNSDEPQRKGSDDEFSKSPSGQKSTSGPSDTWTPVSEKQDDDFAMSPPDPKWSSGSWTPVSDRQDDDFAKLPLILRHMDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLH4</accession>
    <name>A0AAV4WLH4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">arpc5-a</name>
        <name evidence="6" type="ORF">CEXT_748561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ARPC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016339">
        <property type="protein sequence ID" value="GIY83109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.190:FF:000004">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY83109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17098" checksum="226D28BF7D560405" modified="2024-11-27" version="1">MAKNTISSAFRKIDVDQYNDDCYNEEEASEPHSPPTGPDEQEILNLVNQGKHVDALKILLRSAPITTKNQSIKDVAFNLILRVILSIKTSDIEKTVSQLDRDQIDMLMKYVYKGFENPSEGRSAHLLAWHEKVYAAGGIGSIVRVLTDKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WU68</accession>
    <name>A0AAV4WU68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_89981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016626">
        <property type="protein sequence ID" value="GIY85215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WU68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12243" checksum="55E4D45826EA704A" modified="2024-11-27" version="1">MCAFGCTPRGVGAAPSKHLTGICERVQPFPPGSPGNSVQNIFFTIRILSKDYLQNSLPSSSTTNLISLSSEQVILLSSKVYLLLLEIPLNRSTSVVPDHRPRGEYLTADGLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WW76</accession>
    <name>A0AAV4WW76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_773791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016756">
        <property type="protein sequence ID" value="GIY86180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WW76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14206" checksum="E36B9D3715A38DDC" modified="2024-11-27" version="1">MLPGGRLKTLRGDVAICPVSSFLYKVTGRLDRRPAAESEPSCTWYGRPRCELMTFDSKGKAKFYTIPKYWSQILEKTGQDIINIVQKFVPKGVPHISNGYPSCRCFLKRGSRRACKGAKCPPPLPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2I6</accession>
    <name>A0AAV4X2I6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_36308_1</name>
        <name evidence="3" type="ORF">CEXT_801851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017061">
        <property type="protein sequence ID" value="GIY88400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2I6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043887420" evidence="2">
        <location>
            <begin position="18"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY88400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="208" mass="21190" checksum="A1E8FE9DEAF6F41D" modified="2024-11-27" version="1">MFAKVVIFCAALAAAHASLVGPLGLGAPVLAAGPLGLGLGKGLIAAPAVATVSSQRTAINHVAPAAPIGAAAPSLSPMDSSVTDSSPTDLSPTELSPTDSLVMDSSPTESLETDLSEMDSSPTESSVTESSPTVSSPETESSPTDSLPDTELLELLWLSEPDFSVPQSVSESESSVSVLLDPSVLVLEKLSCKLLQLFDVHLIYFVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8X3</accession>
    <name>A0AAV4X8X3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_19281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000026">
        <property type="protein sequence ID" value="GIY91597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8X3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15274" checksum="E2629C258FF306C8" modified="2024-11-27" version="1">MPIQAVRCWPKEGANAISSPCEEREREPKRRTCPHHIPQSTEKQKQQVPEKLWGRSSSFIFSGVNQRRGEGQGVPKPRPNQFERASRSSEPAIRVLGCWSSDASHSNLLAGPGEGGAVHDPPSPCTHTTKFPIGTQARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XA64</accession>
    <name>A0AAV4XA64_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_172201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017356">
        <property type="protein sequence ID" value="GIY90856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XA64"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7669" checksum="B845016AD5A32EF7" modified="2024-11-27" version="1">MSRAPYHAPLPCQVLITERWTTAQNKSGGHLPRMARRSLGHQCLGGQINRYAEREACGAGGEQEFMKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBR7</accession>
    <name>A0AAV4XBR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_278971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000132">
        <property type="protein sequence ID" value="GIY92366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8158" checksum="26A9847656953988" modified="2024-11-27" version="1">MADSSDVYGQLKKDPKCEVITSLMTAYLGCDGLVYALDELLDAGEERAADWSTPVNKPRTRSQVNGLFTSKKSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XE60</accession>
    <name>A0AAV4XE60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4604 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_10013</name>
        <name evidence="3" type="ORF">CEXT_475061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017495">
        <property type="protein sequence ID" value="GIY92088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XE60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027911">
        <property type="entry name" value="DUF4604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040219">
        <property type="entry name" value="KIAA1143-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31195">
        <property type="entry name" value="GEO02494P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31195:SF2">
        <property type="entry name" value="GEO02494P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15377">
        <property type="entry name" value="DUF4604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4604" evidence="2">
        <location>
            <begin position="5"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY92088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18641" checksum="C8FE8A7B4D7306AE" modified="2024-11-27" version="1">MPKRSVAYIKPEEPSFIKKMKAAMGYQEPDTVETKKFFHKELFSKKVVHKTDSFKKEVVPFQDDQVERDDEKPVVVVLSPDDLTEEEAKTITEKADVNKKIIFTKPVKKTGEEKNSLDFSSKKRDDLQKKLSSQRDQNTKVKNTSLLSFDDEEEDEEDMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIW6</accession>
    <name>A0AAV4XIW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_369231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000386">
        <property type="protein sequence ID" value="GIY94388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9312" checksum="DE50AD3FD653D115" modified="2024-11-27" version="1">MQHVRYSVKVFRQQPNFSTGLKHADVDPQLQAQNHQCRPFILAHGNETHPQNLDHHIETYDTWNQNFGEFPHHLEEIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQA9</accession>
    <name>A0AAV4XQA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_617021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018153">
        <property type="protein sequence ID" value="GIY97345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="10051" checksum="FECB5B6DCE348A74" modified="2024-11-27" version="1">MFLSHFSFNKKVNILRHHSCCKRCSFPLEVFHVVGPFIRHHQQKRITEDDERIFFVGILEYYSVLRMRAPPRRVGLKSKTVECC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSM6</accession>
    <name>A0AAV4XSM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_652921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000748">
        <property type="protein sequence ID" value="GIY97175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9956" checksum="3D0F33956451AE44" modified="2024-11-27" version="1">MNVILSKANPIFSPLLRNHLLKTPPRMSTTRVQGKKHLNWDQIPCSYIKVVGYTGIEKPLFQILPSLRWPLCLTAACWDSLRIPSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT07</accession>
    <name>A0AAV4XT07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Titin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TTN_1</name>
        <name evidence="4" type="ORF">CEXT_309241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018278">
        <property type="protein sequence ID" value="GIY98286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="38"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY98286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25142" checksum="556861F0EEB68E85" modified="2024-11-27" version="1">MLFFNSLSTDHGGNYSCVVTNALGRDSYSSHLVINVPPSLMQEPADQTLEENNVASFHCQASGFPEPIVTWMREEGSKDSFEDERIKTFPNGTMVYLMLKKTDEGIYKCIVSNNIGQDLNKIVSLTVIVPARFEEKFTMKNVRRGETATLKCEAVGDKPLSITWTKDKAEIDFKKHTRLEKFDRDIEKKRCRSAFRRKSERQKYGVDSQCHVVRTLFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT75</accession>
    <name>A0AAV4XT75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 4 gamma 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EIF4G3_1</name>
        <name evidence="2" type="ORF">CEXT_758931</name>
        <name evidence="3" type="ORF">CEXT_758932</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000855">
        <property type="protein sequence ID" value="GIY97922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01000855">
        <property type="protein sequence ID" value="GIY97928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="578" mass="64340" checksum="4384EB1920EECF8A" modified="2024-11-27" version="1">MLKTEKSITSSEKKPPLFSFHDLSETNSDSLMKCKEMLKTEKSITSSEKKPPLSSFHDLSEANSDSLKKFKEMLKTEKSITSSEKKPPLSSFHDLSETNSDSQKKVTLKNSCPEDKLNLLNPEEEKQYSSDFLQQLQSHPLFLIKYATCAASLPTVENDSNQDMNKSVAASQERIFPNAGKPTLGYSDLVDGYSHQYGTCAASLSTVANYSNPNMNKSVAASQQGMYPNAGMPTSGQHHQTMGGPVPSPAIIMQTVQPMSRNPPITLPVVIVSQKSISKSYNVPRSMPSMARNHLAPVVNQPGQQPSSQFSHMSMVQPAFHPPLPLVVNQFPQSMYPQRHTPEQYPAMISPGQHLYVNSYNFNTPPSQNSNGNYPTHGMSSYQSIQPQMAPQTIPPPQLQQQPAQHRKGGKAIPVLDPNTCKNIFTTEKITDESDEKNDKSIGVQFASQVAAVLNDNSNEQPSKPQAESIRITESLNISSEKETMMNEEPPVSELVDELANIEDLSEIELIENQHNTFNDTSIVYYRKDIEENVKEHIDNSTSYQKVDTECVIQDNEQIADTVLEEQPQLVINYYYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUD5</accession>
    <name>A0AAV4XUD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_31528_1</name>
        <name evidence="3" type="ORF">CEXT_497731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000788">
        <property type="protein sequence ID" value="GIY97515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043719333" evidence="2">
        <location>
            <begin position="19"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="28877" checksum="7281D592B454F395" modified="2024-11-27" version="1">MLVVKITLCGLLACIVQTSPTYYRPYYRERASYVEENRGDKNGFREYDEGSNHNRQKLQASHGASEHGNGQSYSIRDRIKKNRFNEGSQSSKHGSETKSHDKGSTNQGHKDGFEYNESKGDHKSGEQFLRDLADEGKKYNRGSQSHGSKLELHESSSNHKIGKDIESELDSEFRNSDFFKRSGPIADYSPNYIPHEYMFGIDNTLQRFRYLSGIHGLGGIRANALNYGYNPLRYKYLENYMDDKFFSFRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXK5</accession>
    <name>A0AAV4XXK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquilin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Ubqln1</name>
        <name evidence="4" type="ORF">CEXT_41461</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001051">
        <property type="protein sequence ID" value="GIY99489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14399">
        <property type="entry name" value="UBA_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01808">
        <property type="entry name" value="Ubl_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000001">
        <property type="entry name" value="Ubiquilin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000077">
        <property type="entry name" value="Ubiquilin like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="10"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="515"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY99489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="565" mass="61811" checksum="5B6707F2D11DE9A3" modified="2024-11-27" version="1">MADEESAPKISIFVKTAKEKKSIEIEQTASVKELKEEVARQFNTSIEQVCLIFAGKILKDHEDVKSHSKHKSGLTIHLVVRTGNVQQQTNQTSSPPPQSPSNPPGGNMFGLGGNLGGFPGMGGLGNLAGFTNNPAFADMQQRMQRELMNNPEMMRQLFDSPIVQSLFSNPETLRDMIMNHPQMQQIMERNPEISHIFNNPDLLRHTMEIMRNPAMLQEVMRNQDRALSNIESVPGGYNALRRMYTELQEPMYNAAQEQFGTNPFASLISDNGDPTSSQQGTENRDPLPNPWAPGGSQSPTNPQPPTGTPPNILGSPGMQSMFQQLTENPNLLSNLNTPFVQNMMQSLAANPEFTARMISSSPLLADNPTLQQQMRNMLPQVMSQLQSPDHQNLLSNPAAIQAMMQIHQGVSQLQQLAPNMFNVGQVGNPAGASTTASTDTTATTTSTTSSTPSTGTTTTSTTTSGSTPNPSAEGSNISGTEAFTQLMANMFSMAISDSQQQQQQQQQQQQQPQQPPEERYRSQLEQLANMGFANREANLQALITTFGDISAAVERLLQSHQFNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y161</accession>
    <name>A0AAV4Y161_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_87631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018635">
        <property type="protein sequence ID" value="GIZ01171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y161"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8470" checksum="0CB8AFCD2C031BFA" modified="2024-11-27" version="1">MIQQLNFSRVGALGFSIESEPFEKDHLTRQSFCGKMGDGEMSLSRGEVVKLNDLSFFWGVFFRVEVLVVLAMAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6Q1</accession>
    <name>A0AAV4Y6Q1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_152069_1</name>
        <name evidence="6" type="ORF">CEXT_97971</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018760">
        <property type="protein sequence ID" value="GIZ02144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6Q1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIZ02144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="13946" checksum="B27C3C17B2BBB3AF" modified="2024-11-27" version="1">MTCKGCIIFTIGVIGIYLSGCDTTWNVVCLFIATASVGFGFAGSLITAVDMSPTFCGVLMGFASTVGSFAGYAIPITVGLLTNGGQTLAQWRKMFLITAAVGAGSSVLFLAIGSTDIQPLRPGLVQRRQHEQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6Q7</accession>
    <name>A0AAV4Y6Q7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_569041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001398">
        <property type="protein sequence ID" value="GIZ02135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6Q7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13869" checksum="7EA6E524874330D7" modified="2024-11-27" version="1">MAKPSFATIAKTVPNKAPKQNKQTRPINKPKYITTIKPVEKEILERLINEFKANDALNASYNISRTVARKPQIICFEVSTDTGETQLVESLRKQFWKKIYQSSSRYKFGRRFLNQTSLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDD6</accession>
    <name>A0AAV4YDD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_686291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019313">
        <property type="protein sequence ID" value="GIZ05417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12575" checksum="4A410A336F884507" modified="2024-11-27" version="1">MQTSLACGNKPLPRYAILFFVKIDKKEYDMSKQTTCIGMRVNGLCKVQTRGSIRSRKKKCTLKGDRVCVRSINSEGTRGGLRLEDDATSSKKDSVCCNLTFSNRLRNFDVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YG00</accession>
    <name>A0AAV4YG00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Buccalin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BUCC</name>
        <name evidence="3" type="ORF">CEXT_307901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019295">
        <property type="protein sequence ID" value="GIZ05351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YG00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005184">
        <property type="term" value="F:neuropeptide hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="entry name" value="Serralysin-like metalloprotease, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010276">
        <property type="entry name" value="Allatostatin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05953">
        <property type="entry name" value="Allatostatin"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="Adhesin YadA, collagen-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043629828" evidence="2">
        <location>
            <begin position="43"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ05351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="477" mass="53476" checksum="2C9AF61882E118BD" modified="2024-11-27" version="1">MGYCLENPSAQSGRSPCFAKSGCQLLLVTCMLILLLVNATHATKEIPTKSNNKNEDEPTSNRFPEPIEQSKRGPQSYAFGLGKKSADYPEQEADQAEIEDDIIDALEDESRLEEEKRDGNFERFGFGLGKKRADPARFSFGVGKREKNRFQFGLGKRGEDNRFSFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKRGPEDRFAFGLGKREQGDNRFAFGLGKRSAEDNRFAFGLGKRSAEDNRFAFGLGKREDEDNSRFAFGLGKRGEEGNRFAFGLGKREDDRGRFAFGLGKREDDRGRFAFGLGKRRDENNRFAFGLGKKNEDPTRFINGFEKPEEPTQPPKPTQGIGKRETLNDDIDEYIKRRFSFGLGKRSVSPDMEFAKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YGH2</accession>
    <name>A0AAV4YGH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_587181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019212">
        <property type="protein sequence ID" value="GIZ05121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YGH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9829" checksum="6800F7FC9229FEDC" modified="2024-11-27" version="1">MWVDLWVGRVFWRRLALDLNHLLSKPSICPVSSIFSSILPSLLPPSSKGAIWCKSKMNENPFNSLVNTRRAPEGNLRHGKGTKNKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M3B6</accession>
    <name>A0AAV4M3B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synaptobrevin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SYB_1</name>
        <name evidence="3" type="ORF">CEXT_721621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001833">
        <property type="protein sequence ID" value="GIX66937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M3B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016444">
        <property type="entry name" value="Synaptobrevin/VAMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45701">
        <property type="entry name" value="SYNAPTOBREVIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="2">
        <location>
            <begin position="72"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX66937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18925" checksum="AFE9E713B036277A" modified="2024-11-27" version="1">MENGNEPAPPQEENPQHKVAHKRMQETRAQIDEQRVKWTSIPKLSRKLAVQVTTWPQVSHWNSKEKCRFNIAKGRKLSDLDDRADALKDEASEFGKQTGKLKRKYWWKKLQNACYSHRYMFCGDHNNYRLEADFTAEKLSDETNYLPRLRKIIAVFEKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4H0</accession>
    <name>A0AAV4M4H0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_561201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001841">
        <property type="protein sequence ID" value="GIX66966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4H0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8196" checksum="0CFAD57EE2C7BAAA" modified="2024-11-27" version="1">MKHCLADKCRDDACDQKGLSKRTKQRISKIATYNFKSNTKKAANSTTTVSRRATINLAKQELSGKKENEGQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9I2</accession>
    <name>A0AAV4M9I2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_580121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019515">
        <property type="protein sequence ID" value="GIX68704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9I2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX68704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9452" checksum="B10B3319CF501EAC" modified="2024-11-27" version="1">MSNKIIPVSMTSVTNTMEFFVGALGFVVFSAGRWFGEMEVKTMVCHILRNFSLHSLDSRDKVLPIMNITLQSSARSHQVSTETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAB8</accession>
    <name>A0AAV4MAB8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Centrosome-associated FAM110 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_49386_1</name>
        <name evidence="5" type="ORF">CEXT_111971</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM110 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002003">
        <property type="protein sequence ID" value="GIX68838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025740">
        <property type="entry name" value="FAM110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025741">
        <property type="entry name" value="FAM110_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025739">
        <property type="entry name" value="FAM110_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14758">
        <property type="entry name" value="AGAP005440-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14758:SF1">
        <property type="entry name" value="CENTROSOME-ASSOCIATED FAM110 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14160">
        <property type="entry name" value="FAM110_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14161">
        <property type="entry name" value="FAM110_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosome-associated FAM110 N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Centrosome-associated FAM110 C-terminal" evidence="3">
        <location>
            <begin position="137"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX68838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="25486" checksum="1D3F00557958F752" modified="2024-11-27" version="1">MYLNVNRRSAVERLEETKAHYVKTERVLDCKQNFDERDGSHTNTERLDVKFDHSDFEENSLEPSDESFTVEEDVTEIEYKKQSSRTSDYSKIAHVSPSASANSNFGEKTKPVTRSKSDVSCRFSKNNCVAPEPDKTTDTELERFFNTMGLDSNMFKNLTAPPRSPVHFFESVSSENSETNLSSAGSEDSALEVQKEGLKNSDLQKHAPTETSIVEKNARVVKWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAT1</accession>
    <name>A0AAV4MAT1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_111841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019549">
        <property type="protein sequence ID" value="GIX69124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10166" checksum="875AE2641CFFB8C4" modified="2024-11-27" version="1">MARRSENWSRLEVRAVIRFLRAKNVSASDIQPNRENLWQDVENRSAAGCGRVSSTTTEINTARVEEMIQNDRRVTLREISSELGLSFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD81</accession>
    <name>A0AAV4MD81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_100871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019674">
        <property type="protein sequence ID" value="GIX70402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11614" checksum="4BEF7B72B2DCC5F8" modified="2024-11-27" version="1">MKFKGEKKRNNASALLSATQNNTLVSLEVLKPEKEKSCWAGDKLSANIGGVINNRRLLNVHTSKPNTPSQIVAECERRNKSSGPLSISLTANSTNSRLYLTLKSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEL6</accession>
    <name>A0AAV4MEL6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Mitochondrial basic amino acids transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="21">Carnitine/acylcarnitine translocase-like</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Mitochondrial carnitine/acylcarnitine carrier protein CACL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Mitochondrial ornithine transporter 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Solute carrier family 25 member 29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="primary">SLC25A29</name>
        <name evidence="25" type="ORF">CEXT_304131</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidine(out) = L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:72807"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-homoarginine(in) + L-arginine(out) = L-homoarginine(out) + L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:72799"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:143006"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:70827"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-ornithine(in) + L-arginine(out) = L-ornithine(out) + L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:34991"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(omega)-methyl-L-arginine(in) + L-arginine(out) = N(omega)-methyl-L-arginine(out) + L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:72803"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:114953"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 23">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019699">
        <property type="protein sequence ID" value="GIX70793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005289">
        <property type="term" value="F:high-affinity L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000037">
        <property type="entry name" value="Solute carrier family 25 member 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF61">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="10 22 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 22 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 24" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 23" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="22">
        <location>
            <begin position="2"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="22">
        <location>
            <begin position="91"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="22">
        <location>
            <begin position="198"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00050592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00071763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00076491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00079387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00080567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="GIX70793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="316" mass="34622" checksum="BF9E2DA02761BFF3" modified="2024-11-27" version="1">MAVDFFAGCLGGCAGVLVGHPFDTVKVRLQTQDSSNKIYRGTFHCLTTIVKQESYQGLFKGMSSPMAGLAAVNAIVFGVYGNIIRASSSGNSLQNQFLAGSAAGIVQSFVTSPMELAKTRIQLQGQESRQTRTPFWQRNKIIYKNPLDCLVKAFRTEGVRGVYRGLGCTILRDAPAFGVYFSGYEYLTEKVTDSKGNVNTLSLLLVGGLAGVLSWIVIYPLDVIKSRFQADGMIGSEKKYNSLWDCVVKSYKSEGYKVFTKGLNSTIIRAFPTNAATFGVVTWVFMIFNNTANNKLDVQNANRVLILDQEIQTLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFG2</accession>
    <name>A0AAV4MFG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_63611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019687">
        <property type="protein sequence ID" value="GIX70565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11153" checksum="1DEF180C31D834E8" modified="2024-11-27" version="1">MEDYPKALWATARQVTKKRRRKVVTNHDIMSALYDRRSPLEPGAHPLQSPNGGLFEGLECQRTRVTKDKRRKVVIKSVLHKVPRSSPLQPDAHPLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHR8</accession>
    <name>A0AAV4MHR8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_404181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002218">
        <property type="protein sequence ID" value="GIX71390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHR8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15290" checksum="F5EBDD48A9038D0F" modified="2024-11-27" version="1">MAFLSLIVSEGIHIQRKQLKNCFHYSIPAGHERAKTNQSHFHCDRNHFWTRSFLSLQTLKERERYRGGPSMAIAGALLETTSRYRCSTREVCPVNDDNDFSKVPSPPELGIFLFLFLFPFCEPPHPLPRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIP8</accession>
    <name>A0AAV4MIP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_734191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002259">
        <property type="protein sequence ID" value="GIX71854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18512" checksum="C7F2A4F62EB9DA4D" modified="2024-11-27" version="1">MATGVIPTKEGSDCHDNAEQELNKKEHKGWNGGWGKPLPASLQKSRLITRTQILSDLFPIADCHWAVSDRRLSLHCIRSQIVIALYPIPDCHCTVSDCRLPIAGLYPIADCRWAVSDRRLSFVADCHCANRSQPLSLRTVSQVVIAPRGCHCTVSDPRLPLGCIDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMW9</accession>
    <name>A0AAV4MMW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_616791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019927">
        <property type="protein sequence ID" value="GIX73203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8709" checksum="0944B6EAD7E997E8" modified="2024-11-27" version="1">MRDGIEAARFLFGQGTLEKICSKRDKEVDSKFSLTTPRSSMIKVNQLLGFDSKCDKEIASKVIVTKPRMSTIIQLANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSJ4</accession>
    <name>A0AAV4MSJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_453281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020065">
        <property type="protein sequence ID" value="GIX74396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12637" checksum="809E7B091B8EC5C4" modified="2024-11-27" version="1">MKEFKEMEAVSKVNQIRDPKKRNIAKVISVLQTLISSQLIFQTAKQAGSFWYFSWCPNSNNGRRRTQLISTLYKLVPAVAAITNLHHPTRSQQSLCPKIAGGLPFWGLLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWY7</accession>
    <name>A0AAV4MWY7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">E3 SUMO-protein ligase PIAS2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Pias1</name>
        <name evidence="8" type="ORF">CEXT_59061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020241">
        <property type="protein sequence ID" value="GIX76263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.720.30:FF:000001">
        <property type="entry name" value="E3 SUMO-protein ligase PIAS2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.780:FF:000001">
        <property type="entry name" value="E3 SUMO-protein ligase PIAS2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF94">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SAP" evidence="6">
        <location>
            <begin position="10"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="PINIT" evidence="7">
        <location>
            <begin position="133"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX76263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="54595" checksum="4AC3950BAF5E1551" modified="2024-11-27" version="1">MSEAELRNMVMNFRVTDLQLLLNFAGRNKTGKKQELQSRALDLIRNCTLQVTSKIREIHDRRYRPQLPISNSYDIPEMTASNESPLLPYDLHMNNNFGAQCNPNVRPTPIHQGHTSSSYPSSNKSYVPLPNTNTYSNYNPLSEIKFKELPFYDILYVLIRPSSLVADPSERFQETSFYFTLTSQQAQDVAMSKNANGTYECQIMLRFCLMDISSEQDDNFPPSIGIKVNSKQVSLPNPIPTNRPGVEPKRPSKPVNITPFSKLSPCVTNVISVSWSSTYGRSYVIALYIVRQLNSQILLQRLKNNGIRNAEYTTIMIKEKLQQGQDAEIATTSLRGSLICPLGKVKMELPCRAVTLCDKPALFRTLAIDGLFIDINSKVPSDCTEVQFNEDGSWTPIIPVKEQKDAKKTVEKCQKKKSVEVVDLSDSESEEVWSYDIDTQAVNNTDSPNTPTHPLSPNHLLFASQVNSESFLWHWLNHPIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N010</accession>
    <name>A0AAV4N010_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020381">
        <property type="protein sequence ID" value="GIX78070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N010"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11737" checksum="2BDF96A8FD525424" modified="2024-11-27" version="1">MQFVWNGSTMQMGVIFNVAFTQISCNYYAGIIRGFQYISLLASMQVLWFRGFQHVSVTGSMLNSLDEAFQRSPFRLWQSMWKCVCVENVILLRAMQWYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0Q6</accession>
    <name>A0AAV4N0Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_598921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002770">
        <property type="protein sequence ID" value="GIX77598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12505" checksum="4A8DCBEFCBA5B2B0" modified="2024-11-27" version="1">MFQENYWKKRINHVILACIPCSGKHSTPKTSLNFFQNQIKLPFFQSYPTRLLSFPRKGDGTGYGFREKQMKYFLQIGPVVRFRLVGGIPNQSVAVLALSGHQSKLLLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAG5</accession>
    <name>A0AAV4NAG5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020715">
        <property type="protein sequence ID" value="GIX81802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13413" checksum="58A30012A0CE5AAE" modified="2024-11-27" version="1">MDTKHTPPRAKRKRKIFSFVKGIQKQLPNNSARIHPQLTTSEADSGIFRKFLKLHPQSRLEEIKRDGGKIKGNSRYIWKLKGHNHNVTRNLSIKLGGGNRCLGPRPMRNIFDILIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDG4</accession>
    <name>A0AAV4NDG4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF5641 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_255176_1</name>
        <name evidence="2" type="ORF">CEXT_716921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020800">
        <property type="protein sequence ID" value="GIX82693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040676">
        <property type="entry name" value="DUF5641"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18701">
        <property type="entry name" value="DUF5641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5641" evidence="1">
        <location>
            <begin position="34"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16114" checksum="2B39B86154ACE11D" modified="2024-11-27" version="1">MLSDQVEVQSPYCCLVGGMVGAAYSFSQEPAQLRSRFRKEYLSQLVQKAKATCQELKVGDIVLIELENKKRVMWPMGKIEKIYSSRDGASRVVQVRTSSGCLTRPIQKLYPLEVSTSEILYSPGQLKTGPDMDDCLYQLRNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGV0</accession>
    <name>A0AAV4NGV0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_326491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020876">
        <property type="protein sequence ID" value="GIX83550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="15940" checksum="FAFA08198789358A" modified="2024-11-27" version="1">MCPAAFTYLYIPAHKVAAESSPSPGKAVAKRYHNVTESLPCCKSRTKVLVTEIHTPIFTRATIGIRPEKLCSGRHGSSKLREGKKANNVANGSKYFTTKPQQSARPTGYLEIKTDEFEQNGCGMQMIKTDAFEPNACDMQLVDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNE8</accession>
    <name>A0AAV4NNE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SLC23A1</name>
        <name evidence="7" type="ORF">CEXT_789271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021025">
        <property type="protein sequence ID" value="GIX85064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11119">
        <property type="entry name" value="XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX85064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="338" mass="38233" checksum="4F1B2B654806CD15" modified="2024-11-27" version="1">MQIGNDITKIEALQVKNYYDYYHYGACQLTKEPNPTSINTKANQIRSFIFQVHYIELQTHTIFSSPFPIGHHWKTTYKVQHLYSPVREPVSSTPNSFSVCELLCYLLIPIMETKTSENKIDDTVDKKEDLSKDIDYKIDDVPPGTVSYPYLISPHLCISNDDPTRGYLISTTLFVSGIGTFLQTTVGTRLPIVQGSSMAFLVPVLTILRLPEWKCPERNQNLTLEESAEIWMPRMREVQGAIIGASLIEMAIGMTGMIGFLLNWITPLAIVPTISLVTLPLFAEAAHSASGHWGIALLTIVFMILFSQCLRDIAIPYPKFNLIRDGQLDDFRYLNCFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUC2</accession>
    <name>A0AAV4NUC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_425961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021317">
        <property type="protein sequence ID" value="GIX88404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10225" checksum="AA10D2A043350A65" modified="2024-11-27" version="1">MHWSEHYSEGDNFTQSVSLERWLGVVKTESDWWILAAIASPLYSVIYEHFVFTKVLFFPHGLLLSLLKVFFRSLPYFAYEFRMSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUQ0</accession>
    <name>A0AAV4NUQ0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thymosin beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_108723</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymosin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003741">
        <property type="protein sequence ID" value="GIX88159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUQ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.520:FF:000001">
        <property type="entry name" value="Thymosin beta"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.520">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001152">
        <property type="entry name" value="Beta-thymosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038386">
        <property type="entry name" value="Beta-thymosin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20940:SF1">
        <property type="entry name" value="CIBOULOT, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20940">
        <property type="entry name" value="TETRA THYMOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01290">
        <property type="entry name" value="Thymosin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00152">
        <property type="entry name" value="THY"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX88159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="23732" checksum="A614935831486835" modified="2024-11-27" version="1">MQPNNYATQPPIPSLKALERRDQFKLRRFALSPVVYPHLIWNLKMSSPTKTELPKVPTPLKNELAQFDSSKMKHAETLEKNQLPSKDDVQQEKVHNSMLTGVEGFERSKLKSTETQEKGVLPNADDVVQEKIHQNIVSGVETFDKNALHHTETKEKAVLPSTEIIQQEKGHQKLVQGIENFDTSNLKHAETQEKNPLPTKEAIALEKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUY4</accession>
    <name>A0AAV4NUY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras-related protein Rab-1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RAB1A</name>
        <name evidence="9" type="ORF">CEXT_788651</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021235">
        <property type="protein sequence ID" value="GIX87434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000069">
        <property type="entry name" value="Ras GTP-binding protein YPT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="170"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX87434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22266" checksum="2950B0BD92E170D4" modified="2024-11-27" version="1">MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGKIRTIELEGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNRLLVGNKCDLTPKKVVDYVTAKEFADQLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPPTSAADASRQGEKINPSTPVKAPSGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZ38</accession>
    <name>A0AAV4NZ38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_647671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021310">
        <property type="protein sequence ID" value="GIX88317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZ38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12867" checksum="BED6D104307D2F49" modified="2024-11-27" version="1">MSPVSIDGHVKSQKTSCGGTSSFDCAIEYQSSVGCSKVTVQNRMMKTDLLWQLLLARSKLGVNGYESINGHCHSSAVGLMAYLGFIKGSGALSVHKQFKMWRKLPKLFMCNTAEGFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7H0</accession>
    <name>A0AAV4P7H0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_121261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021692">
        <property type="protein sequence ID" value="GIX92438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7H0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12310" checksum="56935E40CEB32506" modified="2024-11-27" version="1">MKLYLILELYQVSLRCTYKNQIAIKCAAYQKIQSLLETLLGKIFKIPSFQRNIRWYLNIQSMLSELKIVLMENKISMEFAECLLTISKESLPERRTWDGTNDGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9G1</accession>
    <name>A0AAV4P9G1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_680121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004280">
        <property type="protein sequence ID" value="GIX93643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11871" checksum="B0FDF3E03BED6BCE" modified="2024-11-27" version="1">MAMQFKKSDKFFSRNLSNPLQNQENEAHINPDNCSIGCMRHTGTTIRLKAAAKKKKNSPGKASNGSLYQTNFQFQKTRIADAKAIKHLSVVSSNKRREKKKWME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PP95</accession>
    <name>A0AAV4PP95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein broad-minded</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tbc1d32</name>
        <name evidence="2" type="ORF">CEXT_727611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004804">
        <property type="protein sequence ID" value="GIX97649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PP95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032735">
        <property type="entry name" value="BROMI_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14961">
        <property type="entry name" value="BROMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BROMI middle region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="321" mass="36801" checksum="770FD5EA9BE4671E" modified="2024-11-27" version="1">MESLTSGTNAERLEALSTLHRLPTMEHLMHHFSWADVEEGLHNSLASDIIFLKDESLKFYIKMLTCAESKVVLESYLSLIKYFLQVLLPSVNKNFEKIEDFIRQCRRVVEILSILNKFLQNISTHWLRYPQSVIESITIQSLSILSASVNNSRIFPIWTCIAECDPEAKWLKSIMHGHVSRASLLEALSGPSEKNLPDEILQSNRDSYEWPFITEYPVTNVFYGFKDNGYDVSKIFEDMLNGNFKIRYLEEAPRTESKNIDSVFPILKIGTDALQSDLTYPLNHVSLDAANSELQNEELIGISLTQRYGKQLNLIADDDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRR6</accession>
    <name>A0AAV4PRR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_341681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004924">
        <property type="protein sequence ID" value="GIX98519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9525" checksum="A3AF4D6C6EC437AD" modified="2024-11-27" version="1">MDQKTTPSYHSRITRTADELTESYLISVSSTIITVEVQSMQRTTLTSSERTHVLRPIKASSPPGNTCASLSPASKLIRSCCPRRVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PYP4</accession>
    <name>A0AAV4PYP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_716181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005247">
        <property type="protein sequence ID" value="GIY01001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PYP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18700" checksum="946E283E225680FE" modified="2024-11-27" version="1">MNANTRKKERKRGIRRCSGTSQCSWYISMFPDIEAVDVLRPEDPVPFQYSTSFGKKETYSSFGKKTTLAERFHCDLRDVLRSGTFPWGTVAHGENLSVNSVSKATKDVRMTRKKATASSGLRMSTALIYTDALYGSLFCFFFLLVFAFISPFVSVSREKSDVRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1U0</accession>
    <name>A0AAV4Q1U0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_50921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005397">
        <property type="protein sequence ID" value="GIY02000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1U0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14615" checksum="0ED4BDF1C87A8A4C" modified="2024-11-27" version="1">MKEGRKEGRTYERRTEGMKEGRKERMKEGRTEGQKEGWKDGSKLGRKEEGRMDIRDGGRKEGREKEGQKEGKTEGEKDGKKKKEGRKEGRKSMTDGNNEGRRKKKGGTGGRKRMDGRNHIWLNIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q515</accession>
    <name>A0AAV4Q515_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_495471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005451">
        <property type="protein sequence ID" value="GIY02508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q515"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="14701" checksum="850D00E4E5C2FC80" modified="2024-11-27" version="1">MHSPVKHPYSFGFSKSSALPHHPGKGVLDGRHTPYQSHMRGEREREGENVSFRPDADKVTTFGEKWFSIPLSPHPRRAPSLYPVRVFQECQECAIIARTQTHVGPFGKGGNGEMVGGGGGVKRGALGEGAVFSFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7D4</accession>
    <name>A0AAV4Q7D4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_705461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005692">
        <property type="protein sequence ID" value="GIY04272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7D4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10101" checksum="6643B3CBA5AA445D" modified="2024-11-27" version="1">MSFTKIRQLPQSGRHSTFCKLKPFVPEENRPPNCSFKNVNRPSTNEGGIEGEVSWNSLIASDLVRAPARKVARLNRWQFRMPWNCFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q880</accession>
    <name>A0AAV4Q880_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-B22</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase B22 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">NDUFB9</name>
        <name evidence="17" type="ORF">CEXT_112991</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Mammalian complex I is composed of 45 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005860">
        <property type="protein sequence ID" value="GIY05599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q880"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20263">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045292">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033034">
        <property type="entry name" value="NDUFB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="16">
        <location>
            <begin position="18"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY05599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="18142" checksum="0E600A5BDFAE3F6C" modified="2024-11-27" version="1">MSSLLPKHLHLTLKTHAQKVCNLYKRALRNEWSTYDDRWLYRYHAVLLRARFDKHKDEKDLRKAKMLLEEGEKELYDNLHYQPRKFSYSPGGINYGRSVTIPDWVLDFWHPLEKARYPEYFARREQRKQEYIERWEKKYGKPKEAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QC66</accession>
    <name>A0AAV4QC66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitin-binding type-2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_30596_1</name>
        <name evidence="3" type="ORF">CEXT_597241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005778">
        <property type="protein sequence ID" value="GIY04953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QC66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF43">
        <property type="entry name" value="LP10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043528666" evidence="1">
        <location>
            <begin position="18"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="42"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY04953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16172" checksum="5E6ECA9E500CC4F0" modified="2024-11-27" version="1">MKSFAVVALVVLGLAVALPRMKRQAFFLPDGVELIVGPINTNFNCEGLRYGYYADVDNNCQIFHVCHPVTHADGNQETMHYSFFCGNQTVFNQLTLTCAFPEDAVPCQNARDFYYVNDNIGIEDALFLRDEDVARAQQVIQGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCV2</accession>
    <name>A0AAV4QCV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_216801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005883">
        <property type="protein sequence ID" value="GIY05855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11962" checksum="3E1103009226BDE2" modified="2024-11-27" version="1">MYTKYINCFTSLCLNESASRIVLSPIVVALNKMATKKRTLLYLTIMARNHVAQKGRDYSVYDVHHHWQTPLSVTQRISWIKLRPMVSWQLTRGLTKPLWTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMT6</accession>
    <name>A0AAV4QMT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_30351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006592">
        <property type="protein sequence ID" value="GIY10993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9117" checksum="DE6AA2F8FEBA51AB" modified="2024-11-27" version="1">MGVHTDNVSLRSMVVWTPLHRSARPHPDYLAVENYGNLVRPRGRISRIRLVREEDSFGKKPQVMTSGYGNGSHIPTIGFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMY6</accession>
    <name>A0AAV4QMY6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_176771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006382">
        <property type="protein sequence ID" value="GIY09446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="9104" checksum="A7B0A01F255B0825" modified="2024-11-27" version="1">MQPISFITLLRPSAMSFYVPKIHYYRCLFERFPIGRQGEMCLLRSTTEQAEHFGSAEKPEHIIGLARFQLFRIPANKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QR04</accession>
    <name>A0AAV4QR04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_146661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006798">
        <property type="protein sequence ID" value="GIY12488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QR04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8406" checksum="14F44FFBB4F36080" modified="2024-11-27" version="1">MADIEDRTGRMADRRKQRDKVPRNEAFLSEHDRRSPIQPRNLPNTCEDESAVCLRSGHHRCDRRAMFVGCPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRQ3</accession>
    <name>A0AAV4QRQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Paired box protein Pax-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PAX6</name>
        <name evidence="15" type="ORF">CEXT_534251</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paired homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006568">
        <property type="protein sequence ID" value="GIY10847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000003">
        <property type="entry name" value="Paired box protein Pax-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001523">
        <property type="entry name" value="Paired_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043565">
        <property type="entry name" value="PAX_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45636:SF50">
        <property type="entry name" value="EYEGONE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45636">
        <property type="entry name" value="PAIRED BOX PROTEIN PAX-6-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00292">
        <property type="entry name" value="PAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00351">
        <property type="entry name" value="PAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51057">
        <property type="entry name" value="PAIRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="6 10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0371">Homeobox</keyword>
    <keyword evidence="9 10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0563">Paired box</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Paired" evidence="14">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="13">
        <location>
            <begin position="228"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="10">
        <location>
            <begin position="230"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="186"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="271"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY10847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="336" mass="37337" checksum="204FFCF1B3C9B24F" modified="2024-11-27" version="1">MTDQVLQTLSKQMRRLLGRNFLKLYKPKVATPVVVAKIEQYKRENPTIFAWEIRERLISEGVCTNSTAPSVSSINRILRNRAAERAAAEFARAAGYGMYHPYAAAAAFPWSAAAAAAATTPHMWPTFHAGSAGPLPTGSPVDPTAMSGLNPLRDQRQSEVNYYSLFVEQKFCDLFFQTPPGRGKLEAKNSFSPSVNSMEPLWRRHRPTNCPTRHKEPTAGSSWKKNSKKTHYPCVSTRERLAAKTNLSEARVQVWFSNRRAKWRRHQRMNMMKPVNGVVPPTSPTPSLSPVPSPEPVAPSSQPQPPRLMEHLPKMGGENSAFTPASRQTSSSPSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QSM3</accession>
    <name>A0AAV4QSM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBE2N</name>
        <name evidence="6" type="ORF">CEXT_403061</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006610">
        <property type="protein sequence ID" value="GIY11132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QSM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031372">
        <property type="term" value="C:UBC13-MMS2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000015">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY11132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16818" checksum="FBEB44604A358DF9" modified="2024-11-27" version="1">MSSRRIMKETQRLLSDPVPGISAVPDDSNPRYFHVLVAGPEGSPFEGGIFKLELFLPEEYPMSPPKVRFITKIYHPNIDKLGRICLDILKDNWSPALQIRTVLLSVQALLSAPNPDDPLANDVAEQWKFNEQDAIEIAREWTMIYAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVQ6</accession>
    <name>A0AAV4QVQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_565471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007049">
        <property type="protein sequence ID" value="GIY14108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7970" checksum="21109A3AC20CAA55" modified="2024-11-27" version="1">MPQSFVGGTASARVWGVDRLAALAARVVRMVMYFPCSLSDERLTWVSEDIRVDDDAVVYFGRWFCSPFVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVZ5</accession>
    <name>A0AAV4QVZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein fusilli</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fus</name>
        <name evidence="5" type="ORF">CEXT_283051</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006936">
        <property type="protein sequence ID" value="GIY13417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12741">
        <property type="entry name" value="RRM2_Fusilli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12743">
        <property type="entry name" value="RRM3_Fusilli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000041">
        <property type="entry name" value="Epithelial splicing regulatory protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050666">
        <property type="entry name" value="ESRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034980">
        <property type="entry name" value="Fusilli_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13976">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="78"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="179"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY13417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="538" mass="61047" checksum="4815FA9958002EF7" modified="2024-11-27" version="1">MIQHSDKQPLFRYGPLPEVNELAIKFFWVRFEFRKIHLVKRDKTFKVLKGHTFESPEQINTHLEPGICTKNEVVDNNTVVRARGLPWQSSDQDIAKFFRGLNIVRGGVALCLSPQGRRNGEALVRFESQEHRDMALKRHKHHIGQRYIEVYRASGEDFVNVAGGNNNEAQAFLSRGGQVIVRMRGLPYDCTPKQVLQFFASGENPCEVMDGEEGVLFVKKADGRATGDAFVLFQSEEMATRALQKHREVIGSRYIELFRSTTAEVQQVLNRCMDPRTYEQPQPLLPNMPPVPILSPQLLPPGSRKDCIRLRGLPFEAQVEQILEFLGEHSKNIVYQGVHMVYNAQGQPSGEAFIQMDSEHSAYMAAQQRHHRYMVFGKKQRYIEVFQCSVDDMTLVLNGGIPVQRSLISPGGNMLPPPYGAFPYVQTPQILPAVAPLTPRLPAAYYSPVFYWPYPSPPVSPTTYYPHTGTTVLTTECIQVLAQQRSPTQRRRHGDSPAARIEAERALQRKESVEHKQPLHRALFAGLNKKDSRCITPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYX3</accession>
    <name>A0AAV4QYX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_113671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006866">
        <property type="protein sequence ID" value="GIY12918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8524" checksum="47E04294BE9B4523" modified="2024-11-27" version="1">MLAIELGCRMINGVTCTVGPQIFINSFTFADCMYRSKVGLLKPYWPRPAAALSAAEALVRRRNSRELTDTSRFPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R3D7</accession>
    <name>A0AAV4R3D7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_448521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007418">
        <property type="protein sequence ID" value="GIY16823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R3D7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18235" checksum="A5FF8B3D4C4A3725" modified="2024-11-27" version="1">MLGKSAIVAGINWWSILVFYWYIEIKQVNIHLQGNRQIVRRHAKGFIENHAITSHAICIGTVFNLAEYFGILLASRIKKRRMDVTKSVKQFHQVFVRTVFAGDGSAHDLSGGQDDEEGQQHDHSESVVQSKHIVVDSDFRQLGDVANALNHIEHVLLPHCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7D2</accession>
    <name>A0AAV4R7D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_608441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007357">
        <property type="protein sequence ID" value="GIY16292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10948" checksum="D153B054ECD6F7CB" modified="2024-11-27" version="1">MTTASRNSAFPQKKIERKNKKWNLLTNTKCLTNVYATCSGNSNTHKHTHKKKEQNSFLQGRVTLVEANEFDTPRDSTESKQLPVARGVVPEDSSAASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBP1</accession>
    <name>A0AAV4RBP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_400601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007746">
        <property type="protein sequence ID" value="GIY19393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12413" checksum="FF1EAA21877F6349" modified="2024-11-27" version="1">MCFVLQCFFRQMLFKTLEQKLYFVTENNFIRESRIDISWLKANVFTSFQMLITFMVGDLALITSSMSLHHSVNESAFAPAANNSLQMCTCFVRMQFTISCQKKIVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RM72</accession>
    <name>A0AAV4RM72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TD and POZ domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Tdpoz3</name>
        <name evidence="2" type="ORF">CEXT_285081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008199">
        <property type="protein sequence ID" value="GIY22804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RM72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="92"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="29002" checksum="28A3FA944ADA3DF8" modified="2024-11-27" version="1">MFIDLNKKEIMKKKSQYLRDDVLRLLYECDFSTGLVYGEIENMNYGIYSPQTANACLPDLKLAENTTATTNPSAPSVLKRDIELMLHENVLCDVKLEPELETFPAHWFILSARSPVFRAMFQSDMKEKAQDCIHIEDADADTVRRLLLYMYTDECGDLQWESASLLYAAADKYQILSLKDECSFFLKANLDAANACEALMIADLHHDEHLKSTTSEFILKHAKEIFKSDEWIRLIQTNGKLAFDTMLLKYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUA5</accession>
    <name>A0AAV4RUA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_632461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008303">
        <property type="protein sequence ID" value="GIY23697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10815" checksum="7BD3A2C3F233DE29" modified="2024-11-27" version="1">MSWVMRLALVSFTICPKRSLTKWTPSWLPGRRSRCWTPGSSQLVHAEALETKGIQAIRKEVKKVKFRTQMHDQYTKTIKLRNIYDPEDHTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RV55</accession>
    <name>A0AAV4RV55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein madd-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">madd-4_3</name>
        <name evidence="2" type="ORF">CEXT_327231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008553">
        <property type="protein sequence ID" value="GIY25504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RV55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19030">
        <property type="entry name" value="TSP1_ADAMTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="208" mass="23101" checksum="3EC0D078EB11BAC1" modified="2024-11-27" version="1">MPSFSELRPVEVEPCVASCPPPHPPREREPEKMKIVEEEVDASFYSWNTEKFSPCTASCSGGVHTSIVRCLRLPDEAEVSPQLCDQGLKPEPLTKSAMSNPVQSFTGGTSPTLETVPKTIVEDRSLEQVLTFLRWRIPDQEASLRENPGATQPSHPVATLQVPEDKAQSNKEVQSQTLSPTSENDDNNYNDDYNNDNNNCQTNSGRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3G9</accession>
    <name>A0AAV4S3G9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_675031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008822">
        <property type="protein sequence ID" value="GIY27489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3G9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9180" checksum="DDE37D75581C8BF9" modified="2024-11-27" version="1">MLTFTVETEFYEVLKRLKFCEIKFLTSCKKPKIFSPKTGSSGSISKCFYRDLRLHKVPITTDNNKELSVVEFYRLGYAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3M3</accession>
    <name>A0AAV4S3M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_218361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008761">
        <property type="protein sequence ID" value="GIY27012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16378" checksum="4D4871821F476E4F" modified="2024-11-27" version="1">MQGGDRCLLRKCYLFLETVPARDRCYGMRLHCHGNPLLLPSTCGASLYFVESFKDPPHLPYPLRFVLRPVKVPDASFNWNHYQRHLLPPLKRVATIGGREMSRVTPPPPPFRQWVGGRKKSNLPVKLLEHDVIKQEAIKVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3X5</accession>
    <name>A0AAV4S3X5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008835">
        <property type="protein sequence ID" value="GIY27639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7296" checksum="7DE8576B07FB829D" modified="2024-11-27" version="1" fragment="single">MVTTTNQFQSTGYKLQHLETVHYDDVGGLIAYSPTRPESLSAVMIPPPPITVVTLRSSNFPKIRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6L5</accession>
    <name>A0AAV4S6L5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KICSTOR complex protein SZT2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Szt2</name>
        <name evidence="2" type="ORF">CEXT_604901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009101">
        <property type="protein sequence ID" value="GIY29629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6L5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033228">
        <property type="entry name" value="SZT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14918">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN SZT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14918:SF3">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN SZT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="834" mass="95380" checksum="8696DB338E439013" modified="2024-11-27" version="1">MFFFSNPHFYTVAHQSRVKKKHTEGTWKVSLENLLSCRLREGYSVRNVLIDEAKNTTEIRLVLPWMLSTNIEYLITSGPVPGRQWKNNSSDVPQCHFEIIVDGCYEFLHDVTCSDKKPIRSLYRKTVITQFWSYIKNLSNTDQILTQLHSFALNPAYYIVPDSLKNGVPLFYFSTNPATRILQSNDFAPSLTRNISSLQFASFWKTLCLLDINVWQKWMHAHRIGVILQHDTPLQKNLHLPNSSGRYAHVQCRQAMNTLHTVLSELTSFVLVENHSYIKLLFEYEKLPTNFLVSVSHSQENTKTMPYQQKQSDSGLYADAMATLSKYLMQQRWIYTLQYESYSSLDLKSASKILYTLTKVRLHEGFHFSHSSLGIIYMVQEIPVEVPKESCCNLIDRETNCCVVQYIIFPPHTNTTVKDCISEEDDTELTEADGELQLITECWIEPQYGIAIMPPETEYLNGLKFEELPSAIHQKDLEITQVLTTFEHLCAVCQKTPKLPDTSLPIQSKAEADIQVIEQEVQDTQNVPTTENLDSSVSMIENPDNEIEMAEEDILQMNALPLPIYVYNCVSSSIVNQLVQLHKCSPVVDKYENHIFDCECHQEDSKKSTKLNGQEDGKKTVDLILLKEHCSLIEKAFSKAFAYGVYRSLLNGFDIQKCDAIAAIDNICEESLPDYFFFFCPAEDDQLEDDSVMNEREENPEEDKKEPDKCSNLADEDVLSKSCFNTNSSVSSIDKDTELNSLQDKNTFPASYCPLFLLCTKFKSSIKKLSATRLPTCLNDIINCLDSENHEISLDDLKVTLDIYCLTIPPDVENPEVTRRRIYSTSFSSNSPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S735</accession>
    <name>A0AAV4S735_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Low-density lipoprotein receptor-related protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_19885</name>
        <name evidence="4" type="ORF">CEXT_429021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009025">
        <property type="protein sequence ID" value="GIY29129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S735"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042333">
        <property type="entry name" value="LRAD2/Mig-13-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24652">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24652:SF67">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY29129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14358" checksum="DD3DB14EC6F47919" modified="2024-11-27" version="1">MPAQHPDQFKCDNSRCIWAGVTCDGVNNCGDSSDETSAGHPHCPDITPVAITVVVLGITSFIAILVVMCICCCRSESDKSPKLPLIETFPTRPNAGYTPLLDTLLYRDIYMVQWAIHHLSYNLYIHQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBS2</accession>
    <name>A0AAV4SBS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium-activated chloride channel regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CLCA2</name>
        <name evidence="2" type="ORF">CEXT_415871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009251">
        <property type="protein sequence ID" value="GIY30576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="814" mass="91087" checksum="AEBC314AF3A01199" modified="2024-11-27" version="1" fragment="single">DVEAVYRREYADVVITADSSNDRPYTLHQGGCGKEALRIYIPVNNLVDSRQKLSGREFVRLWSEFRYGVFPESGFEGDEKYPAEYRMPGEDANKTTGCRTEPKQLQDDCDEEQGDATRNHYCLPLWTKIYQAAQRCFCEGRLSLGPNHNPESPTKHNLLCNEVGTWFTVLRSSDFTCGRNKARKLPANSAPEFQFMREIEAPRVLVAVDISSRMKEENRYALVKNAFSHFVTTLLPPGSELTVVTFGGNDNVTTIITPRFVVGDDESRTSYLEGQPLPEEPLNEENSCVFCVMSDIIEIAGTKNNSFASSPIAIILTTTQYLEQEKHLILEGVVPLHGIRWHALMMFEDMRPYPSLHTLYSFTGNHFVYVGKDILGDLYRSLNEAINGYSSNLLITQEYLNTFDEDNIWFEFFLDKSISKDLKISISGPAFSSSPLAYGNTKLIDPQGNAMPLRKREIVPSWDLHIENPEIGTYTLKTRRKLGAKSPVLVSVYGCRVSSEEPITARVWTEVLSFNASPRPIQIYAEVRKGNYPIRNATVVAYVKHPSNGGVSVFPLADDGFGNIDITKNDGIYSHYFTNFTSEGFYNVIVKVKGGFDDNPVVLKRYIDFHSVQSCPSSNCCGSAFPWSEQIPTGEFLRQAGPASFEVLSGCGQEDPYPPSKVMDLRISKTYDQIVVVQWTAVGDDFDTGVASSYELKLFRNRSLIRHRFSDPEVQLYSDTIDTTPEAEYGVTLQHLMTIPNLETGLYYLAIRAVDEAGNGGEPSNAVPLWIEGTTAAIQCSDDPTPEKLTSSAGKHASHLLDIMLAIIIALHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGE9</accession>
    <name>A0AAV4SGE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Metabotropic glutamate receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mGluR</name>
        <name evidence="14" type="ORF">CEXT_249061</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009556">
        <property type="protein sequence ID" value="GIY32860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15045">
        <property type="entry name" value="7tmC_mGluRs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.30:FF:000001">
        <property type="entry name" value="metabotropic glutamate receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.30">
        <property type="entry name" value="GPCR, family 3, nine cysteines domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011500">
        <property type="entry name" value="GPCR_3_9-Cys_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038550">
        <property type="entry name" value="GPCR_3_9-Cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017979">
        <property type="entry name" value="GPCR_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07562">
        <property type="entry name" value="NCD3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00981">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="13">
        <location>
            <begin position="73"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00054813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY32860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="361" mass="40719" checksum="1905F130E410E3D6" modified="2024-11-27" version="1">MPMSACSQPCSVGQAKKYVEGSKCCWHCFNCTKYQILRYETTCYDCPLGFLPNVDHTECVRIPLQYMRLDSYWAIGIMSFSSLGIVLTCFVVIVFLKHQDTPVVKASGRELSYVLLAGIFLCYAITFLLVQRPSDIKCGAQKMGIGLCFTIVYSAVLTKTNRIDRIFRCGAKSTKRPSFISPRSQLFICGGIISIEVLFSALWMGFSPPKAILHHPTPDESHLVCAASIDSTYIVAFAYPMILILICTVYAILTRKIPEAFNESKYIGFTMYTTCIIWLAFIPLYFTTTDHDEMNVFTMSITVSLSATVTLFCLFTPKLYIILLHPDRNVRQPLMNHSKYTNNDIRVTSNKAERPTISEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3Q1</accession>
    <name>A0AAV4T3Q1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_653871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010472">
        <property type="protein sequence ID" value="GIY39497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3Q1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10075" checksum="6AE1F65CAD4BADFE" modified="2024-11-27" version="1">MQKENASTAREATQPSTEDAQISQEGTLHSKNGYTPPAKTKTKISLEENSINRQTSPESGKRTYANIIKNQNEQAYLSTNIPSKLPKTQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7R8</accession>
    <name>A0AAV4T7R8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_747911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010699">
        <property type="protein sequence ID" value="GIY41229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10923" checksum="A90F5239043D50EA" modified="2024-11-27" version="1">MSLPKHNLQRPPLCSLSGITVAGTALVVYAQYLSRGVQYLSRGVSCSIVVYTQYSHGITQYPSSARGPIRGHCNHCCSSTLTIYMSVHNLLVGCGFYSYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TD00</accession>
    <name>A0AAV4TD00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_697681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010925">
        <property type="protein sequence ID" value="GIY43074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TD00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY43074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7424" checksum="9D76AA2A58DBF98C" modified="2024-11-27" version="1">MVFKSHPFSPQVFSEARRRPIKKTVRRSFLIVCQQEVADDREVRGASLPTRNGDLSTGTDIYGASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THH1</accession>
    <name>A0AAV4THH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_381351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011210">
        <property type="protein sequence ID" value="GIY44901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7661" checksum="F8E3F77C11539D9B" modified="2024-11-27" version="1">MTAGPDDRVTSALVLGVTGSGSETETPIPKDRIQDRDRTGQDSRYRHLCSVAVATDLASGYRHLCSVAVAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKX8</accession>
    <name>A0AAV4TKX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_184011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011474">
        <property type="protein sequence ID" value="GIY46744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11705" checksum="657480EAD2D30CE1" modified="2024-11-27" version="1">MTRGIPSVKEQNHQQTQNVGSYFGRQVGKCKSTQSLSVLYASQFRQETTLPVTFAFKVAGRFERVHPYNKQTQSSTQSKLLFLSDSNRTVYPRLGSDGSDRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TN62</accession>
    <name>A0AAV4TN62_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_376011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011394">
        <property type="protein sequence ID" value="GIY46280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TN62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11521" checksum="443ADE6012673133" modified="2024-11-27" version="1">MALGKFELRGCQHNSFESLRDNCNESQNASPILQDIPVLGFLWNIERDTLKIDVRNDPQSESVKVIKRYILSKCHKIFDPIGITAPITLFPKNIAPRNVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNM6</accession>
    <name>A0AAV4TNM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Forkhead box protein O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">foxo_0</name>
        <name evidence="1" type="ORF">CEXT_185131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011478">
        <property type="protein sequence ID" value="GIY46764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19922" checksum="56DE16613AE44D56" modified="2024-11-27" version="1">MYMRRPERVFLPPSAPRLVSEAIHRRQPAFRPYNFGSFDWATQPYKVDYYQGHLNMDQLDIDPNFEPQTRARSNTWPLPRPDNFVEPDSDDKGVLPVHLQGHGMGSGLDPTPKKKILPGGMPGATCLMQISLHKPYKVHQKRDLLLHRFMNGWYRMSPTLKIKGTATVLQDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRC9</accession>
    <name>A0AAV4TRC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_81691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011743">
        <property type="protein sequence ID" value="GIY48700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8762" checksum="4AD138AEB7FFF960" modified="2024-11-27" version="1">MESIIKMSRDYSPSHRERGTHIVPRFGSCRLKPFLPKKRGKSFELCFGSQPQRGIRHPLPRFLRQVWSGRGSSAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUF2</accession>
    <name>A0AAV4TUF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011794">
        <property type="protein sequence ID" value="GIY49091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7227" checksum="EC86FB836307A9C8" modified="2024-11-27" version="1">MASNAGGIHNKWEDSVLKCCFVKSPGHQVIGLVYFTESKPTFSSKKPEELRYSATLDVLSPILSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZ60</accession>
    <name>A0AAV4TZ60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_644131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012013">
        <property type="protein sequence ID" value="GIY50724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZ60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="10924" checksum="450A9D6D1F7CD447" modified="2024-11-27" version="1">MKKDSHVFPSVLPRMSRTFHKMKRVLAVPAGSDHGSVRFPESGRSSARARNAGKTGEPPPGSPIDPLRTKLPGKRGLRARAPPGGCSTFQWHLKRGLSDGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U816</accession>
    <name>A0AAV4U816_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_483051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012429">
        <property type="protein sequence ID" value="GIY53909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U816"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16076" checksum="23906AA383807DCF" modified="2024-11-27" version="1">MSHGTDKEVDSISPRCAPSRLARNKTFPSSASHGRILLKKRRPQMARRRCLREIQNGEKKERFSLFQNRFSPRTAYQYSTAINIEAIPLAKMAPSTPQCTGARLAAGVRLGYQRPDVTQWASCMSPGAVAVNKPPPLPYLAAAGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UG10</accession>
    <name>A0AAV4UG10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">KxDL motif-containing protein CG10681</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CG10681</name>
        <name evidence="4" type="ORF">CEXT_214221</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KXD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012809">
        <property type="protein sequence ID" value="GIY56770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UG10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099078">
        <property type="term" value="C:BORC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032418">
        <property type="term" value="P:lysosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039843">
        <property type="entry name" value="KXD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019371">
        <property type="entry name" value="KxDL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13511">
        <property type="entry name" value="KXDL MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13511:SF0">
        <property type="entry name" value="KXDL MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10241">
        <property type="entry name" value="KxDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KxDL" evidence="3">
        <location>
            <begin position="31"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY56770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19217" checksum="91639371C31FD4F7" modified="2024-11-27" version="1">MSANNSQDSNISKDGCASLNNISASVVFVQSLQHQVNEQDIQAIIQSQKHMLARFEKTNEMLVNCNALLASRYVGASKELKKHISFLVELKKDLETIFRRIRFLKMKLSQQYSEAFSASSSVFNVLDEEEANRKKSCQLNHSNELNASKNTTAASSSGSRKVPPVHLPPFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UL80</accession>
    <name>A0AAV4UL80_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">cAMP-dependent protein kinase inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_114458_1</name>
        <name evidence="5" type="ORF">CEXT_700301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PKI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013070">
        <property type="protein sequence ID" value="GIY58497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UL80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004171">
        <property type="entry name" value="cAMP_dep_PKI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15416">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02827">
        <property type="entry name" value="PKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0649">Protein kinase inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY58497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8230" checksum="8E227A5E3A061122" modified="2024-11-27" version="1">MAMEVENQAASPAFDDFLQTGRTGRRNAMPDITADSATISTASLPDSLQKLTCSDLQMDSSCSGQNSGAGQSSQAGPSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UN46</accession>
    <name>A0AAV4UN46_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_566421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013167">
        <property type="protein sequence ID" value="GIY59135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UN46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8824" checksum="27C771FABA4B8279" modified="2024-11-27" version="1">MLLIIHRDLLPFFLGKEKSKRRVALGKFYEKIFFERARGFYDPKRTIRIPSCEYDEAEEVAKLLQTCSDGSEGCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1Q8</accession>
    <name>A0AAV4V1Q8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_613021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013838">
        <property type="protein sequence ID" value="GIY64161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1Q8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="345" mass="38306" checksum="9EC69B3A0279D3D8" modified="2024-11-27" version="1">METMVTIISVQKLLPKLIPKAKAQLEGNTSSPRHQLLWKATPHLQGNTSTGRQHLISKATPHLQGNTSTGRQYLISKATPHLQGNTSTRSQHLISKARPPLQSNTSTGRQHLNSKAKPQLESNTSSLRQHLISKATPQLEGSTSSGRQHLISKATAQLEGSTSSPNSSGRQHVLSKETAHLEGNTSSPTQYRIWKATPLLEATPQLEGNTSSPRQRHFWKVTPHLQALLEGNSSSGRQHLISKTIPLLEGNTNWKATPHTQGKLEGNTSSARQHLIWKHRRHFMGRSSKTVDQVKSATVHPLAWLFVVCIRQTVTMKCYLNASPKCHSSKLISSMCWDFLFHQYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VH51</accession>
    <name>A0AAV4VH51_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alpha-latrotoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">CEXT_215731</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="14">Homotetramer in membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cationic peptide 01 (latrotoxin) family. 03 (alpha-latrotoxin) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014579">
        <property type="protein sequence ID" value="GIY69726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VH51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="12" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="16">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY69726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19730" checksum="FAE78583DCED165C" modified="2024-11-27" version="1">MLAQVTARYKDVSGFLSPSSPPPHFSSYLEINGTNAWVELSFGCFRTLRLCQKVAGYSPLHQAATEGHEEMVKLLLKNGCHVDTQDELHGNTALHEAAWKGFSRTLEILCKNKANFYIKNYGGFTPLHLACQNGHNQCCRNLLWQPANPMSEIAMVIHHFTQLQIWSRRGTENSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJP2</accession>
    <name>A0AAV4VJP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_359711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014677">
        <property type="protein sequence ID" value="GIY70517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9288" checksum="BC4B45DD7211DAA9" modified="2024-11-27" version="1">MLFPQFDNVEILRSFISERREPPCTSEMKPCVAPPRSPAENPTKENEHGGKKKPESKREKNIYVHVQPSTQRTPTVRSTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVC1</accession>
    <name>A0AAV4VVC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger A20 and AN1 domain-containing stress-associated protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SAP6</name>
        <name evidence="7" type="ORF">CEXT_334641</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015212">
        <property type="protein sequence ID" value="GIY74395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050652">
        <property type="entry name" value="AN1_A20_ZnFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634:SF149">
        <property type="entry name" value="AN1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="6">
        <location>
            <begin position="250"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY74395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="315" mass="34762" checksum="83793FE39FB3CD3C" modified="2024-11-27" version="1">MSDEEKKSDLDAKIVSSTVNNMLSVLDRNDAVHDISAGYEADQSSVQDISNVNSPRIFHKKTMETENHTCNRNSSKPGKITFARESSLEITGKKNENNVKDDSKNLRSALKPIRRLPKYKDVKNETTSETNPTDFKGHLIQESSSEGTLADVEDNIDSTSNGDISYNLEKGHDGTKTIPESSGGQSSKTISALAPSVDISKESSTRIPIKSASMPLKKNSNLNTSQLPCSEKKMASSSTSQLKIKSDVARHTKRKCFVCNKKLGLTAITCRCGGLYCSQHRYDKEHNCTFDYRSLGAEEIRKNNPLIVAEKIPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VW31</accession>
    <name>A0AAV4VW31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ELAV-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ELAVL2</name>
        <name evidence="5" type="ORF">CEXT_402711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015166">
        <property type="protein sequence ID" value="GIY74075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VW31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12650">
        <property type="entry name" value="RRM1_Hu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000017">
        <property type="entry name" value="ELAV-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034775">
        <property type="entry name" value="Elav_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="21"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="108"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY74075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="16245" checksum="F2FA6018A7AF83F1" modified="2024-11-27" version="1">MNGMEGGGGGQQNGGCEDSKTNLIVNYLPQTMTQEEIRSLFSSIGEVESCKLIRDKVTAGQSLGYGFVNYVRAEDAEKAINTLNGLRLQNKTIKVSYARPSSEAIKGANLYVSGLPKAFTQQDLEAQFSPFGRIITSRILCDNITGNSGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWR3</accession>
    <name>A0AAV4VWR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS_1_like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_208730_1</name>
        <name evidence="8" type="ORF">CEXT_716611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015269">
        <property type="protein sequence ID" value="GIY74890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF30">
        <property type="entry name" value="SUGAR BABY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="32"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY74890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="361" mass="40236" checksum="C76B01CB1148A36D" modified="2024-11-27" version="1">MASGTAGQKPDLGKDGGEKAAESFWHIDKEMLRFKIHFLLHSGGLVAAIPFVSLFAKEKLGLAASSLGAVLTAQMFLYIFTKPLIGYIADYFNRLKAIICVLTLITISCYFSLLALPKIKREEAFNSFVSFSSNATYLKREFVKINENETDVLFNADSSQLSITHQLELEDKKFLLCSFKTDLCFHVYTRYMLMNETENNVGYYIQVQVDKEEEFVTFCNGNNSFDLCACHGPSPCHDSSSECMSLFCSDVLTTKETNSNESLFMCSTSTQKLDTIVVSCSAQNITEDHAMESQRTFSDFHTFQFWVFAFLLSVSSISENANCTLSDTACCESVQKSKADFGKQRLWGSVGWGDSQPSGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W441</accession>
    <name>A0AAV4W441_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_777721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015567">
        <property type="protein sequence ID" value="GIY77008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W441"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="13093" checksum="44B5F7A8F495D76E" modified="2024-11-27" version="1">MILKDDRKNTTRILKDDRKNTTMILKDDRKNTTAILKDDRKNTTAILKDDRKNTTMILKDDRKNTTLILKDDRKNTTLILKDDRKNTTMILKDDRKNTTMILKDDRKTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9N4</accession>
    <name>A0AAV4W9N4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_292611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015779">
        <property type="protein sequence ID" value="GIY78676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9N4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14229" checksum="94E4A074B1A4AAA8" modified="2024-11-27" version="1">MPTRNLKVSGKIPLQLSAEARWNGRGCFHREPSPSLGADFALPGLGREPGARELLSGREGNLKGSLDQITERHNESLSFILKDRERTDVLAACPRKRKRIVKWSPSRGGVLKLGVSLGNKEEELYSIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WN68</accession>
    <name>A0AAV4WN68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_54341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016429">
        <property type="protein sequence ID" value="GIY83788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WN68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20856" checksum="FD188010EAE22516" modified="2024-11-27" version="1">MQLNLRLESICGLYCRRCFLGLCTYATTIFEDSNPLMGSLQFAVFRHDEIMHLCNYYLRFESTCGFYCSCCCFQKFGLCSVCNYYLRFESTYGLYADAVFQKCSDYARANYYPEIRIHLWALLQIAVFRRDEIMQLCNYYLRCESTCGFYCRRCFLSENRIMHLCNYYLRFEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WS06</accession>
    <name>A0AAV4WS06_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PBZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_676281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016531">
        <property type="protein sequence ID" value="GIY84599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WS06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039253">
        <property type="entry name" value="APLF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019406">
        <property type="entry name" value="APLF_PBZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21315:SF2">
        <property type="entry name" value="APRATAXIN AND PNK-LIKE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21315">
        <property type="entry name" value="APRATAXIN AND PNK-LIKE FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10283">
        <property type="entry name" value="zf-CCHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBZ-type" evidence="2">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY84599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10483" checksum="519E92D1474205DC" modified="2024-11-27" version="1">MCRRNQNHTDQFCHPGDSDYASEPESTQKNDVVEMSEDEECSPKKECPYGDNCFRRNPQHKKDFKHTKKSAHREKLPSKQIKRQKFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WSQ0</accession>
    <name>A0AAV4WSQ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_452241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016717">
        <property type="protein sequence ID" value="GIY85945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WSQ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8802" checksum="4C3D3A624BA03791" modified="2024-11-27" version="1">MKPSQICRQERPPTHNKNDNCCSTLPRVIQNTYRPPLFPNPRCFCRIPSSSSEGGGEACVERTRVSRAVAACRLRLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUL5</accession>
    <name>A0AAV4WUL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_112561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016650">
        <property type="protein sequence ID" value="GIY85365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8927" checksum="41F8437834B895EA" modified="2024-11-27" version="1">MCPESADQRNREIETDECSPEKFEEPHPTGGPHPRGVSTGVRISEYHPNLHGFIRAAAHKPLITKSNRAARLMGCKAHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAJ6</accession>
    <name>A0AAV4XAJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein MON2 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mon2</name>
        <name evidence="3" type="ORF">CEXT_757381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000072">
        <property type="protein sequence ID" value="GIY91931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043887424" evidence="1">
        <location>
            <begin position="17"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="2">
        <location>
            <begin position="105"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY91931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="240" mass="26641" checksum="06F628E046F5E855" modified="2024-11-27" version="1">MTWKLAVNAVLKVLQAGLPVARKYSAQFQGMWIDLAYALEDFLFSASSPSPTQSLEDQQCDEALDCKIILLIRDGILPYANQLPREFIIRVVTLLNKGSIHSATNNSPVGFSFLESGIDIDDDGVVNLLAVTSLLHRFKEVIHKYAEDERLSGKCPLPRHRMSEISFVLKAVATLAKSLKQADPEKVFEWTVWEQLISLYPSLVDCTTSTSAQVCCSLREALHEYADLLEPPKNGLNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBH0</accession>
    <name>A0AAV4XBH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_378671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000150">
        <property type="protein sequence ID" value="GIY92512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13913" checksum="883D2F62CFF7A340" modified="2024-11-27" version="1">MSQRGVIKEFSQLFFPNLQYVWTWDSLPDTKTMDVFSAGDDGKPPYRQPPDPPLGSDEFLYLHLETITKIIELKAKLLADWFRPKGLDPESASKLDKEYDATTAEMLELCKGLGNISQRTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XE50</accession>
    <name>A0AAV4XE50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_224331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000244">
        <property type="protein sequence ID" value="GIY93191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XE50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="207" mass="23306" checksum="768547E960E416E0" modified="2024-11-27" version="1">MPPPELEPESRDTECQRASHSAIKRLSKKSHPPKTEVFVGHFRRATLGEVISVQNSIMSAQKKKKEKALCCRRCSAVASNARLKSDHIRELLNLLVTERVKLFVGGSVGRLFYKGWLCLCCSISALYGDDKRTVHSCLRVPFTPKAPRNGSWQNSILLNSSPLSSGAFCCLIIPSERPDREKRYPTNSRDTGQPGEREKAFFWRSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEK2</accession>
    <name>A0AAV4XEK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_756741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000134">
        <property type="protein sequence ID" value="GIY92386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="301" mass="33483" checksum="36FBF99C8E908BBF" modified="2024-11-27" version="1">MLYISREWRFGGDLQGGGRGPLHQPAASVRGEEGRVGDPERNINDMYPRIVAREREHQDKLDLMERTKTDDVRLKIESSKFVVENGNLTWMLQDANRQLSYYQEEHEILLREVNALKHSTTSMEQDLGWSPRGPLSSRPLPPIMARLSTPVAPIRSAPFVPSPPALSPRISRVSSLQGARPPSAMMDVSPATEFLGDASPPPQILDLSGMSSTSGRRSSVAASQSPQMQDYLGDVTPPSEILNISDLSDTGRSPCRLKWWTNPRCSEECHPSGGGNSFLFQGKWRRNFRNPLARTAAEDVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHM7</accession>
    <name>A0AAV4XHM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_126301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017662">
        <property type="protein sequence ID" value="GIY93450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13792" checksum="CFE29EE130900E4E" modified="2024-11-27" version="1">MRSSSRKTTSPPPFWSLENTKWNSRRMNCQTFLQHFSWNLEHLLNFLNLSDILNMPLSKMDEIFLTKNKSTLSGDNKKWNSRSSTPLPAVSRNSIFSMATGHNDGSFLTTLFQRGGLSCCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIQ5</accession>
    <name>A0AAV4XIQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_181304_1</name>
        <name evidence="3" type="ORF">CEXT_338351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000401">
        <property type="protein sequence ID" value="GIY94532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="2">
        <location>
            <begin position="181"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY94532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="323" mass="37524" checksum="4994BDA6EAF55EEE" modified="2024-11-27" version="1">MPARRKGTSLGRRTKKSAGMQNIRAHRRDEQIQEDNADVRVINTRRAIDQQRQQVHRAFTSDSFLRLAFQYEPDVEYYAHSKVDIGTMDKECPHCHALKFKNEPAVLCCASGKVQLPEIETPPEPLYGLLIGMDPDSSLFLKSIRTFNSCFQMTSFGATEIVQNNAANGAETNKNVSSKDYYAYRLMIRCGQDNVILRCRELCQQFMVDMYVKIESERLRYLRHNQQKLRAEEYIHLRDAIANNADTAEIGNSVILPSSYIGSPRHMQEYIQDAMAFVREYGRPCFSSRLHVIQNGRRLRRCYYQDKMQYIVMTLQHVFLNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK05</accession>
    <name>A0AAV4XK05_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lipoyl synthase</fullName>
            <ecNumber evidence="3">2.8.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Lias</name>
        <name evidence="12" type="ORF">CEXT_554531</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01017912">
        <property type="protein sequence ID" value="GIY95427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000036">
        <property type="entry name" value="Lipoyl synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF0">
        <property type="entry name" value="LIPOYL SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="162"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY95427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="412" mass="46416" checksum="4D1922C005D94B23" modified="2024-11-27" version="1" fragment="single">ENQTVHQMALFSLEMAGCSARFAIIRKGIGKQSIRSCIANFNRFYSLSYSKLTNGSKIEYQKYFLSIFRKSSSKKFDSGPDLQDFIAGVVPRGSTSADYKGELVRDVNDRKSRLRLPPWLKTKIPIGENYHKLKDTLRSLNLHTVCEEARCPNIGECWGGGEFGTATATIMLLGDTCTRNCRFCSVKTSNAPPPPDPNEPINTAQAIADWNLDYVVLTSVDRDDISDGGASHIANTVIELKKRKPSILVECLTPDFAGDLDAVATVAFCGLDVFAHNIETVREYQRHVRDRRANYNQSLEVLKHAKKVRPENITKTSIMLGFGETDDMIKATMEDLRSADVDCLTIGQYMQPTKTRLKVTEYVTPEKYKYWEEYGNQLGFHYTASGPLVRSSYKAGEFYLKNLVQHRISKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK32</accession>
    <name>A0AAV4XK32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_646671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017859">
        <property type="protein sequence ID" value="GIY95023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8411" checksum="AE8CC7462446FB2F" modified="2024-11-27" version="1">MKSDMKSLREFGIVYDKENFTYETIGLVFRDKASKRFKPLKMTPFSKSPVIPGYDPGVGLVGWSPKKIKIPEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMH2</accession>
    <name>A0AAV4XMH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein crumbs</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">crb_1</name>
        <name evidence="3" type="ORF">CEXT_219121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017970">
        <property type="protein sequence ID" value="GIY95852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY95852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12547" checksum="46FD64DF2B7A956D" modified="2024-11-27" version="1">MLVANSSYNSDLFDLKLESGHLQLIVGRGFIGCILQGAGVVLNDSNIYSYEVAWGKCPYLLNPLAKDTRLILVFINLVTKIVDALCDKPEYNQCQNGGTCQEDVLGNFTTCACPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN14</accession>
    <name>A0AAV4XN14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein MTSS 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Mtss2</name>
        <name evidence="3" type="ORF">CEXT_68591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018062">
        <property type="protein sequence ID" value="GIY96561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030031">
        <property type="term" value="P:cell projection assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013606">
        <property type="entry name" value="I-BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030127">
        <property type="entry name" value="MTSS1/MTSS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15708">
        <property type="entry name" value="ACTIN BUNDLING/MISSING IN METASTASIS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15708:SF4">
        <property type="entry name" value="FI21477P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08397">
        <property type="entry name" value="IMD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51338">
        <property type="entry name" value="IMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY96561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="392" mass="43868" checksum="1B0E4614EDB310BB" modified="2024-11-27" version="1">MESFAEKECSALGGLFQYIINDLKVPKDIGSALTRLCLRHKSVEAKLKIFSSALVDHLVIPLQEKLEDWKKVAYQMDKDHAKAPKGDAKKTLDSAIRDVNSKYHLLEETEKQALRRALIEERSRYCLFVNCLRPVIESELSTMYEVTHIQEVLDSLAKLIEDPLGLPTASEQVILDVKSSETGWSFRTPPGSPYFSWFSKIQYMHGAFRLLSVSSQDSGFTSQDTLFTRLPTPPPMELTDQVNPTSKVVEDTIKDSPSYPDTPCAMSTWPNLQDTLQFEKAAASIAKSQRPHTISSAYERHNRPLLTTHTFRPLQADSDSQLSLSADGECPPELPPEDYADDCSEEATPTHKAYPPPLPLRAEEMDMSAPIIPPKTSSSIAAHKEIRFTSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN50</accession>
    <name>A0AAV4XN50_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_203838_1</name>
        <name evidence="2" type="ORF">CEXT_28211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017995">
        <property type="protein sequence ID" value="GIY96058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF19">
        <property type="entry name" value="CUPIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin-like" evidence="1">
        <location>
            <begin position="28"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="231" mass="26801" checksum="016E86A0D027C208" modified="2024-11-27" version="1">MEVTRPITNCQICKNINSFTVLENVTKEQFSKYAYLGHPLLVRGGCKNWTALNVFDFDFFKQLYNTTKGAYQSVEEECQFFPFRTTFLSLQEVFNMSESRAKMTSKDEETWYIGWSNCNPDISSVLRQHYSKPHFLPDDSELSAIDWIFMGYQGTGASMHLDYVRRPSWQAQIKGSKTWYLLPPPECEDVCTPMNITVHRGDIILIDTNQWYHTTVIEGNEMSVTLGSEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRD0</accession>
    <name>A0AAV4XRD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_108131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018131">
        <property type="protein sequence ID" value="GIY97198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="21507" checksum="CB2A93E86D86AC08" modified="2024-11-27" version="1">MLPISKQKFQSIAATLSEVLLSSCWKASTPKCDSSGSCLDVHSAFITLDDRSQQIMERSPRIRPPQGRGTSFIFASLECERGGVFVAGLEEWRITRTLNLKVLIRRHVEMILMIITDFVCKSYFNPVGETHNSKRSVEFQTEISVNSSDLAELSLPRVAGKRRHPNQRRARMLWVMSGRAVSPVCVYYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSP4</accession>
    <name>A0AAV4XSP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_263121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000721">
        <property type="protein sequence ID" value="GIY96960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21191" checksum="D2E216E05F296DF0" modified="2024-11-27" version="1">MAIVEGNSFDIQNTNVELSTAASDETIMNIGNNNVTLDEAIDDKNNLNIDDNEVMLDAPVSEETVLDFDNPNVVQEAAPEIIPNLSTKGKEILLDVVELMGKIDEKNVFLNNTHVTITRSKRLKARQPEEETISSKAESSFNEMDFKYSSWMITKNCDSVSKRDNPKKRQSPAKQDLHSKKWTLHPPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSU3</accession>
    <name>A0AAV4XSU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_576091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000706">
        <property type="protein sequence ID" value="GIY96813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13537" checksum="42DCECC2CA2063B2" modified="2024-11-27" version="1">MNAQNIIICIVVFHSSHFKNLWSWLNCRAAPKPSKNNHEMGIANLAFDATKEDLDEEQIFQAVEPAQVTVKTEDVPEFAAVTPSLMPSSIGVNFVETMIKEWLLLDLTPSVAMLLIDQLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVC0</accession>
    <name>A0AAV4XVC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_468051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000854">
        <property type="protein sequence ID" value="GIY97904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15341" checksum="44680E9EAC8401E8" modified="2024-11-27" version="1">MGSSELNSLQARKTLSPSSKFFWTILFDGKESGLEDLICLLNQNIPSYYRNHKISAMIIQEAHIANLHAGPTLLAHILIGLWMNRQTRSYPMAFDGNLFKTSLKDFGKGSTMSTCIPFSKEPSGGSLKGIFMLATWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYM5</accession>
    <name>A0AAV4XYM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_649281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001143">
        <property type="protein sequence ID" value="GIZ00271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11641" checksum="7EE7B0F4B3F43DC3" modified="2024-11-27" version="1">MRLKDSHFKLKASRSSLFFGHALGSTVPVSPSGSVTCVNGRQTRRCSSHSYKPSPFQTFFLLIFAHVRETGIHRSPLLELLILMPHKIVLQILLVADLLTILND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2N2</accession>
    <name>A0AAV4Y2N2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_391151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018715">
        <property type="protein sequence ID" value="GIZ01741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2N2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10850" checksum="B74CCE1040A21213" modified="2024-11-27" version="1">MPAKMIARTYDKNYPQKDELCRFTGSDSDLLLKRQSQCPEKHQLIITLGNYIEPSFLVDEKCSIGVTYESMDKTKRVRIAVIAFSLKKSCRKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4D6</accession>
    <name>A0AAV4Y4D6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_359221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018769">
        <property type="protein sequence ID" value="GIZ02188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4D6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11482" checksum="6C87164B75CA1DF7" modified="2024-11-27" version="1">MNVLNKSHFCKVVERKHIIQNFEKPKMESNSNSQSPPIRKLLPPCFWEEKLLFSPDDPLYYVRINTSKIAHHCKSWENSPLKFNSRILQTDSLKNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7B6</accession>
    <name>A0AAV4Y7B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_28851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018876">
        <property type="protein sequence ID" value="GIZ02903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15252" checksum="D24F65183C7F9514" modified="2024-11-27" version="1">MLSSKDERVRFFFQQLRRARAISRQKNTLSQWLSVILRRYVPTFRTPGTLRAMNIYHFPKRLWRACFFNASMAPLLGSNRAERTLSRSLGKVTSFHFLELPAENFDSILRERKSRSAKKGVSGSVIERITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M9Z5</accession>
    <name>A0AAV4M9Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_78611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019556">
        <property type="protein sequence ID" value="GIX69211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M9Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17493" checksum="60D2190AA67C9774" modified="2024-11-27" version="1">MQQCDNGFKSPLLPKHFSSEDFLETYSTFSKSSPKLVVHLYIFLAPRERIHNPSKHLEGRRTRVIGFATLWSLRKREREKKGDTVIQCNIVTTDLNLLFSPNISPAKTSWKHIQLSPNPQLSSSTICIFLSGAPERIHNPSIHLEGRSNIPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MC30</accession>
    <name>A0AAV4MC30_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_313071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019584">
        <property type="protein sequence ID" value="GIX69425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MC30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="2">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX69425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13369" checksum="7AD02C5312422DB5" modified="2024-11-27" version="1">MSHSVLIEKESDIDKQLSFDSTDNNIPTNHLSKIESTVVDTGAVTPKEQGNAINRIDSSVDNIAVNVEPTHSELIRHSAAVERTTKMSGCASGDTSEPGCRNPRLLSAESRSRVGVLQEPREVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDB6</accession>
    <name>A0AAV4MDB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_646401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002001">
        <property type="protein sequence ID" value="GIX68804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11686" checksum="6D7633E6E774D8BD" modified="2024-11-27" version="1">MCTLDAKFPGRWIGWGWIHPLSGTIRSLLSELFPMGPFEKSKLRRGPSCQDFCCCPRRPRNARMVSLKIYADPKYLGVFDFGNIDRKGAAIETLHVLETESPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ME90</accession>
    <name>A0AAV4ME90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_645901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002165">
        <property type="protein sequence ID" value="GIX70747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ME90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10449" checksum="3B0119D13B0DF810" modified="2024-11-27" version="1">MCRSKRRRFSCQRVLGNTSSTHRHWKGPQLSCAFPEHAHRRLPQPNPLPPFPLPKRSHPSAASGYLTEIFQRWNFAQGNGDRAQIESITVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEM3</accession>
    <name>A0AAV4MEM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_248381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002129">
        <property type="protein sequence ID" value="GIX70295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13000" checksum="7DE27F15BF27EC93" modified="2024-11-27" version="1">MRLDCRDQTHWRSLRVANESLIAKAPLLILLALEFRGSRQLSTVATASQPANHQTKCNLIAEIRHTGGVCELLMNPALQELPPNSVSFRIQGGSLVGKVELDRDETLQLELRAQENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGG9</accession>
    <name>A0AAV4MGG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_645861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002165">
        <property type="protein sequence ID" value="GIX70737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9170" checksum="9931ED1CF0A358F5" modified="2024-11-27" version="1">MSSLCLGRNKKQPSCMSSLFRKSEISGFDRDENSRISGSDEPLPRDLASGNSTLSSGPSIRSDQIVICNRHRSDGLILKAMTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIN5</accession>
    <name>A0AAV4MIN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_759811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019779">
        <property type="protein sequence ID" value="GIX71705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9137" checksum="9E39CEBFF01B21C9" modified="2024-11-27" version="1">MPMNSAATATPLHSRGSQTRHCTNADLGTGILASPGTITGAVVNDVISILLWVATITCRCFIEELAWYLPRVPCPVISWLIKKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLD1</accession>
    <name>A0AAV4MLD1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_22601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019769">
        <property type="protein sequence ID" value="GIX71594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19527" checksum="17CE56A0B2BA513F" modified="2024-11-27" version="1">MVIKVWLRGMVIKIWLWCIVISYGYGGKVTGYGYTDNRPLLHIKDSGILVIAIYERKISVLFSPDVEILTREFNFGRALERKQFSPRAFPPFSTSSSVVLRSFILPFYTRVFSADDEEVILLDDGLVVVIIASETNESRPVVGVSRTVFGRDGRFPKWRYKRLTILCLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUD0</accession>
    <name>A0AAV4MUD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Pip5k1c</name>
        <name evidence="4" type="ORF">CEXT_249481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020222">
        <property type="protein sequence ID" value="GIX76066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17301">
        <property type="entry name" value="PIPKc_PIP5KI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF101">
        <property type="entry name" value="LP03320P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX76066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="590" mass="65767" checksum="72D9DBA578D859EB" modified="2024-11-27" version="1">MGSIQLGISYAISSLASKPERDLLIQDFTIVETTTFPKNGSTSTPAHRYSEFTFKSYSPVAFRYFRHLFGIQTADFMLSLCHYPLIELTNPGASGSIFYLTEDDEFIIKTVQHKEAEFLTKLLPGYYMNLNQNPRTLLPKFYGLFCYQCIGKNVRIIVMNNLLPSFITMHEKYDLKGSTYKRKANKSEREKSSPTYKDLDFFERHPEGILLETEKYNALIKTITRDCRVLESFKIMDYSLLVGIHNLDMAKKEKKYELRRQKKEEDGKISDESESASPTSGKTDSGLVRSKSLNKTRLAAFSTAMESIQAEADILEDDDDVPPGGIPAKNAKGENLLLFLGIIDILQSYHLKKKLEHTFKSMLHDGDTVSVHRPSFYAQRFLQFMSNTVFKKCHQSVVTNVLALKHVPSKRKAGSLKKAASATSQELPKVSTENEPLQGEGAVSVPLPSPLPETEVASVSNDLKNLSIPSEGEQIKITTDPVQPRVLSLHSSVGSVTKTTSTVEVVRSQMTESTGDCVLEVTTSTVPYTPPHSIEGSTPTHTEGTPSFTESSMSGDAACPTTPIKILKKSFGLHTVFRRDRIITVLKIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2X0</accession>
    <name>A0AAV4N2X0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Mif</name>
        <name evidence="13" type="ORF">CEXT_812571</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01002895">
        <property type="protein sequence ID" value="GIX79067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2X0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019829">
        <property type="entry name" value="Macrophage_inhib_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01158">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX79067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13700" checksum="B46AEF99C34550C8" modified="2024-11-27" version="1">MQHITIRTMPTFTLNTNVPKDKIPEDFLKSTAKLVAEILKKPISYVVVHVNPDQLMSWAGTSDPCAVATLGSIGSLGTSQNAKISKALFDHVKDNLGINSDRMYITYVDLERANVGYLGTTFADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCE8</accession>
    <name>A0AAV4NCE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_743871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020683">
        <property type="protein sequence ID" value="GIX81485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7970" checksum="27335CC72040AB18" modified="2024-11-27" version="1">MMTFSRLPGALLCLGRGIVERDDEGWAAWCSSLSGKRNCGKEMMRVGLPGALVCLGRGIVERDDDGWVCQLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCI6</accession>
    <name>A0AAV4NCI6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_812901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020783">
        <property type="protein sequence ID" value="GIX82442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCI6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7460" checksum="523D41F939A544D3" modified="2024-11-27" version="1">MLNLVFQASPLMKPNIEASSDEETSKKNAKYEAVSASEFSSTSTAIVDVGPEDHSIEDNSIYAEVEYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDB5</accession>
    <name>A0AAV4NDB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_157261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003268">
        <property type="protein sequence ID" value="GIX82765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9473" checksum="1BCE8134D3C72F9F" modified="2024-11-27" version="1">MRGIAEEYLTIVDPYLPSRMVPSKKERPSRYDGKIFRSNFRGEESGGPHLIYKSRIVLSITDFRVQYFNGGWRRGRGIFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGG5</accession>
    <name>A0AAV4NGG5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_309721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020867">
        <property type="protein sequence ID" value="GIX83449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="13892" checksum="60DDBD8BC829822B" modified="2024-11-27" version="1">MVAFYMFGTEAMYPKNCLNLIVAQYPTESPFAAAWDFYGGLTQKARPYLRLGTLPAAVKIVWCQKRRGTGRNTANDQLEISPASSLPQNVFRKIKKRRAVSLEKEQTISARGVLKQVIVRGGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIA8</accession>
    <name>A0AAV4NIA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_675961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020925">
        <property type="protein sequence ID" value="GIX84049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10259" checksum="09F0546DC4BD2A61" modified="2024-11-27" version="1">MVNDHEAACTFPFLYLLQPNFLRKSVYNLFRGSQLISSKVTLSRNTQCKPRMAICWECSAYHTGGTDRNFHGKQEVVFPATRPAVRHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJ20</accession>
    <name>A0AAV4NJ20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_812771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020915">
        <property type="protein sequence ID" value="GIX83946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJ20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13221" checksum="1B50CA01C9F6B122" modified="2024-11-27" version="1">MANLPSHKTLDTWGIKYYEVHSEREPCVSGSFQLPGLGTSIGMYHFENIAACRSIRGLESTTLKKYTCQARFYRGMQNIFSLLLVSFILAVLLSGHIIIIFTFSKIHQTTDQSGHCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM74</accession>
    <name>A0AAV4NM74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_516071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003455">
        <property type="protein sequence ID" value="GIX84836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10135" checksum="2BED491CF6C78C89" modified="2024-11-27" version="1">MEGAQLVECAKFPQPNPKRALSKSYTNQRELGAKKTIAVQGLLSNPASSRPGHKSDGGGTRRPMKFDVGPVSQTASWGPSNNSGVVPRATFALNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPE6</accession>
    <name>A0AAV4NPE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_137091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003477">
        <property type="protein sequence ID" value="GIX85062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13580" checksum="B4A2D004A970C840" modified="2024-11-27" version="1">MEVQGKDVFSKLEDKVSITQKGDNGRLGSYLYRSPFGQGDEWALKSNWREPLCPNSKMDCNSALFEWKFRSDVKQLFLIGTGSDIVLFSDWGWVQSLFAGRQRKIERFIGNFMGTVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NT54</accession>
    <name>A0AAV4NT54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PARP-1 binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Parpbp</name>
        <name evidence="2" type="ORF">CEXT_523731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021279">
        <property type="protein sequence ID" value="GIX87984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NT54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18525" checksum="1E3141614D12D4B1" modified="2024-11-27" version="1">MAPLADLLKRDSSCDVRSTLDEDSKLSNISTTLPYISYFHHSESSSFGGVCIDSQTPTKLSFKNVLQDSGDNKRTEVSKTNKNSLNSKKGCKRSILREITNENPPEKIKKGDEKKKSKGPLKEANVERKNKSLPKNEIKTKTKNSKKFKLIEGQGKITSFFIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUC7</accession>
    <name>A0AAV4NUC7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_97891</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the WD repeat peroxin-7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021226">
        <property type="protein sequence ID" value="GIX87333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005053">
        <property type="term" value="F:peroxisome matrix targeting signal-2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044536">
        <property type="entry name" value="PEX7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027:SF1">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="31"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX87333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19301" checksum="3661B3D8F2573B8A" modified="2024-11-27" version="1">MGWALKDFLKALVDSDEICGILFQQKEVSAFLEHSNQVFQASWSPHCVETFASVSADGTLRLWDIRTPQQSIACYHHDSEVLCCDWDKIDSGIIATGTSSGKIFEWDVRKNDGSSFILSGHEYAIRKEHSEFVFGLDFNPKTRNEVCDCAFGIHYCAFIIIGHKILGIIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2U2</accession>
    <name>A0AAV4P2U2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_217831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004033">
        <property type="protein sequence ID" value="GIX91532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2U2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11933" checksum="F9908C5FCEC1F281" modified="2024-11-27" version="1">MRAVLEDPGGGGGWERESKQCGMRPLPIVCLLPRIGEYLPNLHTCANKNGALMTEGERFPEIILAICNYLSFGCFIRKLHRVSYTEKNFSVIKYDYLSMYLILSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P978</accession>
    <name>A0AAV4P978_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH_48 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_341911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004277">
        <property type="protein sequence ID" value="GIX93616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P978"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044547">
        <property type="term" value="F:DNA topoisomerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046975">
        <property type="term" value="F:histone H3K36 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042800">
        <property type="term" value="F:histone H3K4 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000729">
        <property type="term" value="P:DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044774">
        <property type="term" value="P:mitotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007050">
        <property type="entry name" value="HTH_bacterioopsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052709">
        <property type="entry name" value="Transposase-MT_Hybrid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46060:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46060">
        <property type="entry name" value="MARINER MOS1 TRANSPOSASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04967">
        <property type="entry name" value="HTH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH bat-type" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12968" checksum="2736E3A1DA9E63E4" modified="2024-11-27" version="1">MLLKQEKKIIRCVWRCIDRTPVPKLVCTIFFPRNFDVEDVLRSNRPFEADEGKIKELFDTDHRITTREIAEKLNLSNSTFHYHVKCSGLISKLGIWVANVLVERNLLFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9F4</accession>
    <name>A0AAV4P9F4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras association domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Rassf8</name>
        <name evidence="4" type="ORF">CEXT_82492</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004287">
        <property type="protein sequence ID" value="GIX93684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9F4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16134">
        <property type="entry name" value="RA_RASSF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033593">
        <property type="entry name" value="N-RASSF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048945">
        <property type="entry name" value="RASSF8/10_RA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048944">
        <property type="entry name" value="RASSF8_RA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15286:SF6">
        <property type="entry name" value="GH01133P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15286">
        <property type="entry name" value="RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21712">
        <property type="entry name" value="RASSF8-10_RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-associating" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="371"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX93684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="626" mass="71493" checksum="A31BA783EC6F3DB1" modified="2024-11-27" version="1">MELKVWVDGIQRVVCGVTEASTCQDVVYALAHATGQTGRFTLVEKWRNSERFLAPQEQPLKVLTKWGEYANDVHFVMRRSTGDQKQSSGNSQSQSNNNKRQHDFLRGFSPSGGSNKQKVSLNNKEIKKSLTFSCGHGSSGSVSSDNSTPPIINECTQPNCETSSNRNIKNREGRSKQDLPKGVVRGVPQRPRDSESPNSKIERPKYPPSYDEAVSRSSGRFPTSHLSLATTASSHAQDEESPSSKRPHLANRADQYSPVDRGPSSSQTQNHIRQPNSHKNHLMDQMRDFHARSPDITPITSERSSPSRTKSPSRSPEKTSQLSYNSISDDSLKLKKTLSAKLEIDKQLTNENKNLSPKTCQPEELSRDPQYQDLLRLVSLQREKLDNQQAELSQFFDVQVYKIIYWEGRLQEQEEKLSVLQEEVCHLERTHHEQEGELIQLDRRSFSEEVELGRQEERTLRSELTLARSQLANCETELLQCRQRIRLLLEEIAEEKRVKSLREEQERKEQEEQERHLQSQVDCLQQQLKDKMMESDSQKAATEQAKEELQELDMKLSEKQKEMDILMADIREANLRSLSLIPSDEGKLVLEGNFYNRPGSTRKIIGSPRQLENAVPTNKNPHGVWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAG2</accession>
    <name>A0AAV4PAG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_264131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004201">
        <property type="protein sequence ID" value="GIX93141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8458" checksum="82B79BF381DA99BC" modified="2024-11-27" version="1">MIDKNAEQLISSSSPFRYGIHNSVINGHGQQLQSRLSCGGGYFFLSSIDPLDTQGAKHLYQAPELHEQVSRGRVEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNM4</accession>
    <name>A0AAV4PNM4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_547061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004781">
        <property type="protein sequence ID" value="GIX97454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="10"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9171" checksum="88F11A79C89E442F" modified="2024-11-27" version="1">MPSCTSKRCPEGCTIILCQFGLWDTSELSFEDFKRMALVMLFQILRDPMNQINGLKFIHDFSELQYIISNTALLRICSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQ05</accession>
    <name>A0AAV4PQ05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_661461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004904">
        <property type="protein sequence ID" value="GIX98408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQ05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7908" checksum="708202C3FDB45153" modified="2024-11-27" version="1">MQKVCATDGWGKLQRKFCDFPYLFPFGCVTGHCSETLQKEEEISCEKKIFRNLIPVHIRVLTRWCEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUA5</accession>
    <name>A0AAV4PUA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glyoxalase domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GLOD4</name>
        <name evidence="1" type="ORF">CEXT_538831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005090">
        <property type="protein sequence ID" value="GIX99741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043193">
        <property type="entry name" value="GLOD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46466">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46466:SF1">
        <property type="entry name" value="GLYOXALASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21701">
        <property type="entry name" value="GLOD4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16533" checksum="7507413AA1417420" modified="2024-11-27" version="1" fragment="single">LRIAPVNHEQAFGRIAFSCPTAELSGIQEAIKKADQKILTPLVSLDTPGKATVHVVILADPNMKWDGHEICFVGDEAFRELSQVDPKGESLLKEALIADKSDEWFAKKGLSKEEKERYSKDNILSLDCMVIPKKTLPDKPIAPITPFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZK1</accession>
    <name>A0AAV4PZK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_594471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005338">
        <property type="protein sequence ID" value="GIY01557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11632" checksum="16349331E3AB4A54" modified="2024-11-27" version="1">MARICLHQKPLFRLKVKRLIMTKQLMCETLEEPKQQLSGPHKASHHLPYFLRPSESVIERPLRVSPKGDLSSGQEECHPSWGDKLFFRPPRSIIERHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q009</accession>
    <name>A0AAV4Q009_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA mismatch repair protein Msh6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MSH6</name>
        <name evidence="7" type="ORF">CEXT_744421</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005493">
        <property type="protein sequence ID" value="GIY02745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q009"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000005">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY02745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="494" mass="55585" checksum="DA0E4F367206A5DF" modified="2024-11-27" version="1">MKRPKKQGSIIPSHGVDKEYDIAIAEINETKRELDTFLAQQKCTLNCKVSYVGSGKNRYLLEVPENKKVPRDFEFQGGRKGFKRYYTQETKDLLAQLIAAEENRASALKDITRRIFEHFDAKVTYFNSILEVYILYCLYNNFKMWKTAVHCLSTLDALLSLVLYYKSSGVTMCRPKFSIPSQDVEPHLEIISGRHPTFLKYFTGDDYIPNSVYMGPKRDNELEDINSGGKLVLVTGPNMGGKSTLMRQAGTLVIMAHLGSYVPAESMCLTPVDRIFTRVGASDKISKGESTFFVEASETSSILHHATSDSFVLIDELGRGTSTYDGTAIAYAALDYLANDIGCRTLFSTHYHSLVEDFCGHPNVGLGHMACMVESELDCPALEKITFLYKFSDGACPKSYGFNVALLAGISRNVVRQGFLKAQQMEFSVKISKALRRLLSVKAPEEIIEALDKKYNFFTENKVIVFFIIVICIYTCCLYSELYIFACNKLDLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0S1</accession>
    <name>A0AAV4Q0S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_575221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005369">
        <property type="protein sequence ID" value="GIY01787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18017" checksum="B7CAB34FE6383779" modified="2024-11-27" version="1">MTESFLWYCRVLQHRVRGPVHRGNVPEDVQPRLPGLLREPVQPLRLLRGDQLHPGDDPSLHRRHASPGRLRAALRAPAQDIQGHKVLDVAVQPGGVAHQLGALHRQLAAASVLVHHDLRPAGHAGVRGRFNYKNLEEKPRHNFDSFVQALLTVFQILTGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5H3</accession>
    <name>A0AAV4Q5H3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_281101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005744">
        <property type="protein sequence ID" value="GIY04695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5H3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="16585" checksum="7EE856E02B932B4F" modified="2024-11-27" version="1">MHEDLRRIYQSLELITEEIESTILIASNVFYLIEQGVYALTALDPETLNGDECRAREPESTFLINRLQEHRKDIEHIMRMYEVTVGEVKDRNLPTLLSRLESDIKWKIKDLFNQVLYKELLVYCYQIKLEFRQNLTNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8W1</accession>
    <name>A0AAV4Q8W1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_172478_1</name>
        <name evidence="2" type="ORF">CEXT_16641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005751">
        <property type="protein sequence ID" value="GIY04797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8W1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15002" checksum="2287F55C78B8BE56" modified="2024-11-27" version="1">MMGLFVSLVYVGLCATAYQAIKAMYFNFSYRIVMFNGPLALHAITSLFTLAVPASGVHSALEKIADTVSMIKFRNVAFRNKCLFMLKMQNGRASLVIWSSCKIDKVSAFTTVFFIFTYSIALYEIDKSELEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA27</accession>
    <name>A0AAV4QA27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein piccolo</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PCLO_0</name>
        <name evidence="2" type="ORF">CEXT_542481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005795">
        <property type="protein sequence ID" value="GIY05057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13694" checksum="7D650F33E5F70FD6" modified="2024-11-27" version="1">MVEQQQQRIYGSDAYFQTLNNEINRLRRSSENLYRDTIYDKPTWGGPVVQAQTPVPEIRTSPQTTERRKRKEKKTRKPRSWHPSPYVSEDEDDQMTREEKESENQSRDRSSSTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBX1</accession>
    <name>A0AAV4QBX1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_600391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006066">
        <property type="protein sequence ID" value="GIY07198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBX1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10371" checksum="562DA69FB7AEF962" modified="2024-11-27" version="1">MQGSSGAVGGRRGLIRLSATRKEIGQGGIFCYHSTPLPFSRTGHTPFINAIGAKQDSLSDRDACYANPIKRVSNQYSRTPQMEVWLRRYRVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJR7</accession>
    <name>A0AAV4QJR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_470251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006258">
        <property type="protein sequence ID" value="GIY08492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13239" checksum="B689333D03CCFC08" modified="2024-11-27" version="1">MTHKNVYQGLSRQDRLTIIIFVVNEANYLYNVIQEESYPTSPCGRRQLIIEAASGNLTDLLTVECVFTVRDPSPLKSSKRAASQKYSEECVLERGVEGQDTPLRGKVKGPQRSKYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNA3</accession>
    <name>A0AAV4QNA3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_594561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006577">
        <property type="protein sequence ID" value="GIY10905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12007" checksum="3CA53BFC545EACDC" modified="2024-11-27" version="1">MHESFSLAIQDFILPSIVDEKYSAEQRVLSVPQASCHYDPSCSFAIEIHPPKISSDVTTLIPRYASGVLSLLTPHTCRISRSDAAMLTEIGLLIIQLEYRLWRNSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQX3</accession>
    <name>A0AAV4QQX3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_179291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006794">
        <property type="protein sequence ID" value="GIY12458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13828" checksum="1EF22D633FAE52FF" modified="2024-11-27" version="1">MEVHETKERKLLHVHRWLENEWKAIVSVFNNTEQHHETRCLSEEASVVMAELKAIETPIVYASSNHFSYAKIIRHQTKANVGVAGNELADSYAKQATLKEDIDFHLNSTFKSIKSCPQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWA7</accession>
    <name>A0AAV4QWA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_171571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006954">
        <property type="protein sequence ID" value="GIY13537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY13537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="30917" checksum="DF8B605904692765" modified="2024-11-27" version="1">MFSVNTGEPPTPPNSTATTSPRSDPNAGDVAFRPANQSQDSGYDPSSPFSLHEGPRDGANTFFSEDDVFDDCEDNVLLDIDAEEEDGKERCPNCDTALSCICGRSGSSATDCTNTYFTASSSNCDSSSSYSSLSIRPSSMPIFIPRSCQNTHSNSSNQRLPCSECSSAEINPSTSRQRMLTDFIFNNSHPGSLPAAVISWRNHMSPPLSFAARMARYFNRNQSRTPRMSAPIVSSSSTDPSSTGPNRNHRRRICSEGTSLGLTPEEGHPAARDAAGSCPNEALRKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5K5</accession>
    <name>A0AAV4R5K5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pancreatic triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">X975_15530</name>
        <name evidence="6" type="ORF">CEXT_70561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007249">
        <property type="protein sequence ID" value="GIY15581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5K5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Lipase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY15581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8472" checksum="02B611665C0DAAB7" modified="2024-11-27" version="1">MVGIVLAEFIELLRDVYSIPLSSMHVIGHSLGAHVAGYAGQRLNKLGRITGLDPAEPYFQYTLEEVRLIPAMLNSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9E6</accession>
    <name>A0AAV4R9E6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_481311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007443">
        <property type="protein sequence ID" value="GIY16946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9E6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11600" checksum="7F8308DCE23604F2" modified="2024-11-27" version="1">MTDASNITAILCVSQIACSNIQLLNEIEWGACSIRLMWCGENEGLSISTTAAPRITMIFISARNIDADAAGSRAGRAEVIFAAVFGNSGMRQPRKYEREAIFCLVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAX5</accession>
    <name>A0AAV4RAX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_443241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007681">
        <property type="protein sequence ID" value="GIY18855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11659" checksum="9E2FD701EF3D3D24" modified="2024-11-27" version="1">MTGKEVDHNILQQSSGDAVIRGAGVAYGWVRGTLQEPLRLTKCDPTTVLFWVVWNMTGKEVDHNILQQSSGDAIIRGAGCAYGWNKGDLVGAVTLTKCDQQPSCFGYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBT4</accession>
    <name>A0AAV4RBT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_15801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007737">
        <property type="protein sequence ID" value="GIY19294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10003" checksum="C95C1F2F7339A578" modified="2024-11-27" version="1">MLRVCRGPSFINAPGGAVKAASYDRPFGRSEKCDSIFLTFLTAVMALLDLFSGTKTEMSTVSCTGWTVMMLVRTHLGVFFSMRLFSYFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGX7</accession>
    <name>A0AAV4RGX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ldh</name>
        <name evidence="4" type="ORF">CEXT_606391</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007862">
        <property type="protein sequence ID" value="GIY20264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val/Trp_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="LEUCINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722:SF1">
        <property type="entry name" value="VALINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="3">
        <location>
            <begin position="279"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY20264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="537" mass="59721" checksum="66AF96F38F79277C" modified="2024-11-27" version="1">MALVGLKCTSRLPNVVKNVFGLPSICIVYHANKFLRNKCVTVCCFHRTLHFKTIQFPLKNAFEGREKNVKSLHAYRQYSSKSEKSLLSSCPTEFVDFLKSNKISRCFFAWNESEKRVVASHPELKEIEDWLNDPKSAHYQQHEAVFLAVGMRTNCLLGAFLWKVDRGQACGGIRMTPFTSVEHYLGEGLRLSRRLGVKSALAGLWVSGGKGLILEPKDRQHIQPEFRQKIFYDYGDFVSSLNGCFIAGMDTGVNAFDLYNAHTHTRWMVSGPEDIGGSGNAAAILGKGLLCAMEAALNFLGAGDLSGMKIAVQGAGGIGLAVTSGLLDRGAAHVFVTDTSKKSIGDLHDALASKARGRLKVEKVSIGDNAIIGYDCDIFAPCAVGHVLTPNTILDIKAKIVCGSANALLASERDANLLVERDVTYVPEFIPNRMAFVNAANENYGRMYNDPAIERHFDKNWEHSIYYLTQEILKISSEKNISVIEAAHKLADTYSMQKHPVWPNRTKSIIRNLIDGRWHHGQDFWRKRRNFAKSDCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHN7</accession>
    <name>A0AAV4RHN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 4.1-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EPB41L3</name>
        <name evidence="3" type="ORF">CEXT_111311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008026">
        <property type="protein sequence ID" value="GIY21514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13184">
        <property type="entry name" value="FERM_C_4_1_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000001">
        <property type="entry name" value="Erythrocyte membrane protein band 4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018980">
        <property type="entry name" value="FERM_PH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280">
        <property type="entry name" value="4.1 G PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280:SF21">
        <property type="entry name" value="PROTEIN 4.1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09380">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01196">
        <property type="entry name" value="FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY21514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13249" checksum="1353C6D583AFD8EE" modified="2024-11-27" version="1">MYGVDLHQAKDSEGVEIMLGVCASGLLVYRDRLRINRFAWPKILKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHKAAKRLWKVCVEHHTFFRLMIPEPPPKPKLLIPRLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RMI5</accession>
    <name>A0AAV4RMI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_371041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008058">
        <property type="protein sequence ID" value="GIY21819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RMI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY21819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10956" checksum="FE0D75ADA598A4BF" modified="2024-11-27" version="1">MEKKDRSMEQVDPWRGKDIHGTRGFMERKKTLMEQEEPWRGKKDIHGTSRSMERKKTSMEQVDPWRGKIDPWTGKIDPWNKNIHGEEKLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTU8</accession>
    <name>A0AAV4RTU8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_152272_1</name>
        <name evidence="3" type="ORF">CEXT_632581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008303">
        <property type="protein sequence ID" value="GIY23720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY23720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="799" mass="94291" checksum="193A652F20D6672A" modified="2024-11-27" version="1">MPTRNVRNADILKMVRFTKMETTESIASSQSRSAIGLSRQTRFFAPKRFSFEIRMKHTVRQETRRVDNYFRKNRQSVRNLPILKSTESSVERKAGSKLQQPRYERYLLVPKRELKIPSEERQIRLTNVRRTRNNIRTNAIDYGNQVITMSSRRNGKNLSTLPLRADANRYRFVGITDIRLQAKTSRSSTRSHQGQDKNEHISRQDRVQIRDAKDIRKFSRNNRDVSARRSTVSKQIPVRYDEKEIQGVLNIRIVETRNTNRRQERQFSRYLSNLSSQSRRHLGNGRKENRVTRVSTPIINGERLSRNVRNTRSTTRSHQDQEEKRADFWTISSAISKQIPIRFETQGILNIRIVETRNTNRRQERQLSRYLANLSSQNRRHLGSERKENHVARVSAPIVNDRRFSRKDSRRTQERRIIQNRNLRMESMTKFGMRKTSQNENEIEQKIAAVTRYDQRFSTRSVPQSSRTDRSNERFHEIRNRCRTEEARNIRSRRTNVETRQPVNLLKARNIIHGIFIRSITKDNGISRDRRYISCKPGDVNLSELKESRLTRRIGGKERRYATKMNFDMNRKIISIRYGISNENRLRTSQQSRRVQNEMRDFRRLGLNGKENRFEVRMKGSGSIRINKIKDELRQSNRRIYSGFSRQIPFQSTEKPQRQLRSRTSYENQQRISARFVPNHSNVISKVFSSSNFTSKGNIRFSAKVPNEKSHEKFLISTDRRANQRKLFTESKSLSSKGMNWNLYEYISAYKLNSFISFVLNAMLGLSVVIVSADDKSKNFISRTMTPIVNSFSKFISAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2S6</accession>
    <name>A0AAV4S2S6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_155022_1</name>
        <name evidence="3" type="ORF">CEXT_142301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008672">
        <property type="protein sequence ID" value="GIY26343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2S6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043416631" evidence="2">
        <location>
            <begin position="21"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY26343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="834" mass="89852" checksum="4FFA873F47FDC512" modified="2024-11-27" version="1">MSSAAAVLVVLPLLLQSVQSTFPPVSNAPPIPSQAAVRTVDLSATRYYFTDDVQLNQPPNVIKEDGFIPTDDKLDQRYFAPENQSGETGDFPNSDDTFFARYYSDGQPAIGPVATPVPDDTYVAQPSVTSKVIPDNPVNAGPSDIWVLTKGPNDQYIPERWVQVQVPVQQDKVVEVVNTDVVAPKQYTETVKSFPPVAPLPPPPPPPAPIKAPPVAPPNFVQQIWEAQPLPPPPPPPPPAVTKKSSSAFIVPPPPPPPFKGTDKQTVIVNQPAAPIQDQIAVPVNKGAPLPQLRHIWIPTSQQTGKFITVPVGTVINDKSVPAKGIPVDVPPQPPIAVSDTWVLRQDGPIPRFEEQKTIVSAPPVVQKSNVIVDSSPKFQFDSPKNPPLIQKSIDAPVPADFWPTKNIISEQKIIGPPPPIFNLPPGKSDSVIIGKSAPIAPLPPPPPPPLPPSPKTIISVKGVPQLPLPPPPPPPPPQIVAPVAQVINGKPCPLPLPLPVAQPPVIQQPKNGIVRLIAARPLPVPVPVPVAPRQVAIPVPRKQIVVPASNIKVAPSPVLLYPPVSRIRYSYPWGSYIRSLPITAGKNIFVLPPSNNKVKKASKIQAAKSSSSESSSSESSSSESKSEEEPKPKSKEEEKEKESESEEVAESVGSVETEVPEPEPEPEKEIEDVEVAASVPEPAEEEPEPTEPETKEDSIEVEESQVKPQLLGRGFNDPLANNFENFANPFLYGYDQRSLSGPSQNREEISDPNRRVIGNYGFQNQGIFRNINYVADSSGIKAHVVSNEPGTVSHQTANVNYISNATPENSTNKAQEIDTAASHENLTIDPQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SA80</accession>
    <name>A0AAV4SA80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tyrosine-protein kinase-like otk</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">otk</name>
        <name evidence="4" type="ORF">CEXT_710531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009147">
        <property type="protein sequence ID" value="GIY29874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SA80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF21">
        <property type="entry name" value="INACTIVE TYROSINE-PROTEIN KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043427889" evidence="2">
        <location>
            <begin position="21"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="113"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="304"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY29874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="547" mass="60372" checksum="74DEC302B48B5E7F" modified="2024-11-27" version="1">MRRYLLKCHFLFATQLLVEQLGGGGRDFTFPPPFILSIVRTTAERPNPVSSDSLNTTCPFNNKAANLLRCGGNIFRLPYVRVFASASVVPLGVSGFPYINGIGDQARVVLQSPDSASQLTEKGEMVLRCKVEGSSEVRFEWFHNGLRMFRNERVSFRNKRLQVASLTPADNGIYSCRAVSEVGVVDSTDNFALMLPSDTAARIQVLPKDTIAIKNGSAMFDCVFENAAAVEWYTQTNDVPLSNNSRFIIFPNGSLSISGILNSDEGIYKCVGISDISKEAPQQTYATRLKLAYIEGFSDSPFEPPISPDELKVVALGSQFEVTCVKPNGRPKVKIWWEDPSGHVISDTGRIRVDDSQLIVDGAKKTDTGNYTCNAENIAGQERTSLYFYVASAPTITLPPAGLVTEEGDTAMFTCEFNGSPYPVTQKVVMSDAGDYVCEVVTNGFQPVRSEKAKLVVKEQLKFVPPPVSTRLELGSVTKVYCKARGSSAPVVRWKKWGNHFLIGLHIFKMIMEHLLSKVLLMMMLENTSVLPQALKELLMLQLILML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIG2</accession>
    <name>A0AAV4SIG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_701061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009573">
        <property type="protein sequence ID" value="GIY32986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18342" checksum="2270C0065863F7CD" modified="2024-11-27" version="1">MVLMHEDTYRFWKNAKIMTLTFKIKRKSCPVEKLRWEKLLTFSMGLRNVRGRISTLTGTIIGVVRGSQLISPNGSDSKGEYQIKSIPNPYHFPICILLRNSPAKPFQMIPVRVGKVIDIFDGTEECAGAYINADRNYNWSRPWQSAYLPQWLGFQTGIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIJ9</accession>
    <name>A0AAV4SIJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_811291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009547">
        <property type="protein sequence ID" value="GIY32799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY32799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12186" checksum="E6FFEA76FDBF64E8" modified="2024-11-27" version="1">MHDDGVNPFILEYFKPDLAASCEAREYNILYERISKLEKKALKDKLYLFSSTKASGFVPRKREDLRKRLLQRRNATRYPKMLCNFKSLLIPQANDINAEYRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQQ1</accession>
    <name>A0AAV4SQQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_133941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009928">
        <property type="protein sequence ID" value="GIY35541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11684" checksum="123772A5EDC374C9" modified="2024-11-27" version="1">MPITSVFVISQTPHPQPPLLSKLSLFYRQGERSDGSLLNCNKSPLPEKCQKYLSIPPSPKDSSLKSSAARLHLCSTDKVTSHLWWPYLPLPGQFANERPIIRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXE6</accession>
    <name>A0AAV4SXE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_660471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010302">
        <property type="protein sequence ID" value="GIY38425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="202" mass="22281" checksum="E932574AD728DC9E" modified="2024-11-27" version="1">MEVSSEGNEPAEVHLDLTVAPNADANASTTVTPEGMCRQLVTANKELKILDDILASTKNSDMPQDYLQMNANLLMKRQYLVEWVSKSGSCPIAKCTLHNSNKTTPKSNVKRNASEISSRKDKRNVSEEFLTPNKKLTAKANFTSSKVNNQTEIQTSNKFNSLGTDEVTNVDETVTVRPHSQSVLGYRCSLAPIEPKTPVLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T272</accession>
    <name>A0AAV4T272_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_157577_1</name>
        <name evidence="1" type="ORF">CEXT_752991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010512">
        <property type="protein sequence ID" value="GIY39794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T272"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="19133" checksum="42E0D34DB4B48154" modified="2024-11-27" version="1">MASEFLSDEHLFAIDLLSFVLRQHQIPVRRHLPSCELNRLFRPSIGQAILNYMIQNSSSLHRLWTNFFEAGQTDDESLRRLYSELIQQRPHRMFELLMTVLALHCYRGVSSARADDSSQMVRAMEHIAFVTRTWIGRDPRNWRWFESRVESINRRLKIACAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T354</accession>
    <name>A0AAV4T354_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_21821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010540">
        <property type="protein sequence ID" value="GIY39982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T354"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8566" checksum="C83693067DB28DDF" modified="2024-11-27" version="1">MVRSEKTRTSELAYALVLVLLPLFPITVPLFPTPRDISAYDNAGQLGRGTGVEGGAAQEIFFFSTVSTDRGRTKISAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TC14</accession>
    <name>A0AAV4TC14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">E3 ubiquitin-protein ligase MARCH3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">3-Mar</name>
        <name evidence="13" type="ORF">CEXT_520551</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011019">
        <property type="protein sequence ID" value="GIY43729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TC14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46065:SF3">
        <property type="entry name" value="FI20425P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="12">
        <location>
            <begin position="42"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY43729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="30529" checksum="71B403BBBF4E6A2A" modified="2024-11-27" version="1">MEKQPNSEHGKPQSSDMASSQETKESSEPKSSVQESILLKVSELESNPMCRICYNGPSRERLLRPCKCKGTIEYVHRHCLERWLESTNCETCELCHHHFTTRRTRKSFWEWCRQPETRHDRRNFIGDFTCFAFLTPLGIATFWLCAEGAIYYQKVKNSTLETIALVTLAVFLISPYDLVKMEGSQLACSDRRQVIYIATNFVRGGGGQRSSPEQLSQRTPHSVCATSAGSASGQSALPSSRLRKKHRADHQPYTECTSRQSINCVKLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TPX3</accession>
    <name>A0AAV4TPX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">glt1</name>
        <name evidence="2" type="ORF">CEXT_646291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011682">
        <property type="protein sequence ID" value="GIY48190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TPX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12303" checksum="358489240FBD29F0" modified="2024-11-27" version="1">MEKVPGSEKIFKADIVMLAMGFLGPEQYLLNDIEVEQDPRKNIATPQGNFRTTIPKVYAAGDCRRGQSLVVHAISEGRQAARQIDNDLMKCSSLAGPGGVIPFVTQLTVDSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQR2</accession>
    <name>A0AAV4TQR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_333881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011607">
        <property type="protein sequence ID" value="GIY47647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11802" checksum="C4BFB52DB25D6E71" modified="2024-11-27" version="1">MTCIYQYIVTLEDTQHFTTNDPYSQQPGVASLPSGFHSGDAPDLVRPPAVDLAPEDLDEEGEGGKFREEKKNERMEPNQSPRIVGNGTFPPPFNLPAMQEQFECTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSC3</accession>
    <name>A0AAV4TSC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_798321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011672">
        <property type="protein sequence ID" value="GIY48084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12560" checksum="A2D47AD31BC5B36F" modified="2024-11-27" version="1">MSGPMSEMWTKSPNWGMQGIKMLREPTLHEQGNTAGIICINNNVKGCVTSQRGYSAFPKSQMKIKQSQVNTSFTPKSMIAQKDQLFKILCTNNQRQLSDFNHSCICQHILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVR2</accession>
    <name>A0AAV4TVR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_297901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011916">
        <property type="protein sequence ID" value="GIY49964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7875" checksum="1B5A79ADE83F0E2A" modified="2024-11-27" version="1">MREISMLPASVFPPHTKTRFHFLLQNSSPPQHDEVSSQRLDRPTKEGGRDGHGQIIIPVGDTRRKETKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TW19</accession>
    <name>A0AAV4TW19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_159881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011713">
        <property type="protein sequence ID" value="GIY48423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TW19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11838" checksum="FAF37E502777DA05" modified="2024-11-27" version="1">MDKHLPGRIRSSNGEKSIHYPIPFSRNPLSPGLPGIKECPQQMETGAGCWGAADENSKRQEYRFGICIKVTKPSPNPRHPLFLFFFPWGLPPLSPFLGMSREMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3Y0</accession>
    <name>A0AAV4U3Y0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_714721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012248">
        <property type="protein sequence ID" value="GIY52508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3Y0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9884" checksum="FC1FA44D4DDBEDAE" modified="2024-11-27" version="1">MWRAKRKVVFHVRDADDALGRMNRHGIWEMLVAPQVVKKEFYLCKIFNLLRLFLIGVISHISCKTFQTSSNRCYRLTLLSEVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U754</accession>
    <name>A0AAV4U754_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_222971</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012376">
        <property type="protein sequence ID" value="GIY53590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U754"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000325">
        <property type="entry name" value="ZFP90 zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="269"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY53590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="498" mass="56377" checksum="A0809F5D28F9BEB9" modified="2024-11-27" version="1">MHQQTDCEETSAAEMYSWYDISNHDQNNPATSDFNFPSKPSVKENEYRSVNLQRSSEPSEILRSQNSRHSDASNPGHPASIPMSLAQQVLLPGFQQTFGQRNAMMNRMDQHLEDTSQIEYSGISLTNEVWYSTRNPIHTLNTTEQTETFSFATLACDDPLENLLFSTNNLSGNSDENIFNNPETDNTNNITDPISIPGNSHFSVENQQSCAINFDAKKYKVAENNPKYDKRTDFSYGKADSVFGASNSIETKQHGFGSGIINNIELYTSESSSSDSGSSELNTSFEQKQSSKSDKDPIALQPSDHLEFPECPRPVARLYKCKFCDKAYAHRSSLSRHVRIHSGENRINVRNVNIVLTNIEIPQCEYCNTYVTNFEDHNCVLFGNQHRRSYANIPQNTNGNLSEDIDLSAAGHMHYEVRSSPMYQMDISRQQSIPSDMHQPINCKETAADEMVPQYGVANKYGYNPESSDFLFPDMYPFQENEPHSTHLQLHLKRAKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8R2</accession>
    <name>A0AAV4U8R2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_437621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012488">
        <property type="protein sequence ID" value="GIY54252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8R2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="8068" checksum="13C7075D6D32CA09" modified="2024-11-27" version="1">MFQLGSTFPSISPRMFDIELPFLEERRHLSCDSRGQRRRATAAHLWRHLEKYRQENLIVDRAGVLSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U9S9</accession>
    <name>A0AAV4U9S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_7174_1</name>
        <name evidence="2" type="ORF">CEXT_302291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012524">
        <property type="protein sequence ID" value="GIY54548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U9S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="361" mass="40534" checksum="7C3632A7B2254FCC" modified="2024-11-27" version="1">MGRSPYWTVSTKSKKDKDNLALSSDVQPRRKDESTLTHPSIRLNPLAKIYPAQLAAHLIETNPWLPSPKNSALDNGWTSTSGIRSSSIGSESLESISGSGFGSQSSGSLWEGFSGEPWSGFRSSGRSPSSNRLPRVTLERSGHRQRPVVEPDRLSFYDEDTPYCPVTYCRPIPRSAWMNFRELTTDILEKTTASPEDDGESSDEAYSEDYIHVEDQDELPLGVMRGSKNSPPDTGSPQADSACGSDRDNSSCSTTPLSETPASSSVSRKSLVESKEMLQDKVQRLRERERHLVDQRMQEARAEEILRREEHLLLQRELVQFRRLLLLQTLSELRNQLEKQGKRFHRNYGEETANSEGGEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFU6</accession>
    <name>A0AAV4UFU6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_118421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012793">
        <property type="protein sequence ID" value="GIY56687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13905" checksum="CE043D6FE61C120D" modified="2024-11-27" version="1">MVAYITHSRAFFTFKTPLPVNHEGAKKVKAHKPRHDKRNRIFFLIRYCPFIPTSLYYAGERNRCHNREALTRGVGHLRRHVPDSGNHWEIRKSKQGGHFDTRDTHLESFILTNFFCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHB6</accession>
    <name>A0AAV4UHB6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transient receptor potential cation channel subfamily M member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TRPM3_1</name>
        <name evidence="1" type="ORF">CEXT_242191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012866">
        <property type="protein sequence ID" value="GIY57158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20514" checksum="0AB14358D6ACB815" modified="2024-11-27" version="1">MFFVHYSNVIDNTNWHAQMHKDLYLTLDWNSPHVAMSEVFLKDPSNKFKIDKEFSMKQYYVLKESFVDLFLNQGFQVHKYLTPRRLILLFRKVRHQEFFQTICWEGALGYGPMSDIKRNFIETDLNWLIEKTTSMENFVSSQELSLNAMGMYCTDPSAAERKAKSASDILGHIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJ10</accession>
    <name>A0AAV4UJ10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_122581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012952">
        <property type="protein sequence ID" value="GIY57721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJ10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16319" checksum="B33042F2393FE193" modified="2024-11-27" version="1">MPESNTELPISFETTKETISISSENKSIQDVALSTFSFSTSSNIVLSNTIKRKPQTARRGKKKLISNERPTNENLNQNSSLTYDDVFLKNADLLPNQFNNLQHCSEKGIFPYLDLPGNSIVEKPKKKASLKRKKYSNFCFYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULV6</accession>
    <name>A0AAV4ULV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_36961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013105">
        <property type="protein sequence ID" value="GIY58783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11654" checksum="9B5728A25836AD2F" modified="2024-11-27" version="1">MFNDTTQHTSRQAIKQRREERAQLFANCIKPKLGLSQSVTKWVCKHSTAGICHFTASSCFNFAASAHLCHLPQLALGHFGELLEGDRTLNLALSNSLAFPAVGLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4US39</accession>
    <name>A0AAV4US39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_447691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013347">
        <property type="protein sequence ID" value="GIY60594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4US39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11806" checksum="EC9A24251228E54F" modified="2024-11-27" version="1">MQSMHKRNNGVGLEEEEDPSPNGTRFGMKRSEWTLKPAGRPLLTRNLLEENDGARKYFQCIDGRKKTALRRAVVSSKARSILTAKNVLQSNTRFKFLGILKISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V901</accession>
    <name>A0AAV4V901_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_528461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014117">
        <property type="protein sequence ID" value="GIY66421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V901"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="20770" checksum="87C6BD3DC0B046A2" modified="2024-11-27" version="1">MAKVIVLDIVLHKGIRMSGAEAMGQNSAQEAFSASLKETRPRAKTARWNIHPTDSKEELACAISPFSAFGAIALREDSSILKLGLLSAKWAIRKTGGLGAKTARWNIHPADSTKEKLECAIFPFPAIGAIALREDLCILKLGLLSAKWAIRKSGGGGKKTVVAVDADHFYSFICAVKRFKKKCNLGSNFIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VRY3</accession>
    <name>A0AAV4VRY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_814921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015006">
        <property type="protein sequence ID" value="GIY72893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VRY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11091" checksum="390DDD5EB2A8B9B6" modified="2024-11-27" version="1">MVKSRSGGMVNGPTHSTETAPVCQYVGLHCRGAKSVQRTTWTFGFDCCTQTFRVTAVLNTIDSLILSQKLNEKRPFIKKKCQRHFAFTLHHTGFLRQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSJ3</accession>
    <name>A0AAV4VSJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_688861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014931">
        <property type="protein sequence ID" value="GIY72315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8336" checksum="5B08848208AB0E9B" modified="2024-11-27" version="1">MSSQTRPTFPPQRTGGNHQKRCLSMFRSGSDSIQSSFVTFPLSPKPDTGRILQSRNKAAISEFNHSRHHNRAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2X6</accession>
    <name>A0AAV4W2X6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_753181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015456">
        <property type="protein sequence ID" value="GIY76259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2X6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12513" checksum="894AE907F514D45F" modified="2024-11-27" version="1">MSIRPIEDVDPEVLKEVEKEMQNEETIKQNKDISPVPETLDAEKSEADVKYDDMPEAMLPPPEIPIVGVLDVEKKDEEMEEKTTMDKEPELELKAESEISENQKKTHYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7D2</accession>
    <name>A0AAV4W7D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_156691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015717">
        <property type="protein sequence ID" value="GIY78118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13525" checksum="D4923D9BD70B41A3" modified="2024-11-27" version="1">MRGGRATSLIGLNILIGNSLVDFRITQPGLDSCPRVNSACLHTLLAAYTNPIHFSTLSRATISGIVQHHRQPSPLDIKFGYLELASSQKMPFDCFEGIQESFKSIMDSTFASASFRICSFLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W906</accession>
    <name>A0AAV4W906_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_386411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015750">
        <property type="protein sequence ID" value="GIY78359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W906"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7578" checksum="5E083DC1808C722E" modified="2024-11-27" version="1">MSSPAQRISVPSPKQALSKPFGRGIFYPDSAQGTRNGLMAQSAGRMSCQKRYFSALLRSEFPSHVAKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLW9</accession>
    <name>A0AAV4WLW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_630671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016253">
        <property type="protein sequence ID" value="GIY82533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10780" checksum="ECF5614069C5B411" modified="2024-11-27" version="1">MLEAPRRTPEQSNSDLKYVINFNMNSIFCVDGTQKKSSKLVQVPRRSKNKAHNWTQEQSSELVETPRRMQKYSPELLQEPRRTQELSSELVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTK2</accession>
    <name>A0AAV4WTK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_651911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016672">
        <property type="protein sequence ID" value="GIY85648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14713" checksum="2103B574DFE2672B" modified="2024-11-27" version="1">MLLLLFNGRTTHDTPRISYTAGRCFSFYGVVLSAPGISDASAKSIKISVRLTEDNEEVSLKVFCLVSRYLDYFTLVSRQEMLGLRVGLAPHELVDLKIRCIYLFRHTLRDRTVEESKTNKDFFLKLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYJ2</accession>
    <name>A0AAV4WYJ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding cassette sub-family A member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ABCA2</name>
        <name evidence="3" type="ORF">CEXT_421591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016862">
        <property type="protein sequence ID" value="GIY86926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYJ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY86926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="578" mass="66226" checksum="6A210D65EFD8A00E" modified="2024-11-27" version="1">MDEIPIIYKSIIEDPVAVHDSFTKAAEMQIGDLIFNRNDFMEMLIKNFSLPSAELEAFLNSSLVPEKMILKFSMEMEYPLMPTSDLLTGQDPDLSVIVDSFTFNSIEHPSLEHLYDLLAYLERHKGKFKVVWGVIEKMFDSRLDVTVTNDDIGAIAEELKSIILSPSGLRELMCQKNGLPSVFKHENEVITNKSSELQIALCSMNQTTMNKLSKELQKYIDVEKLRETLHLDNWNITLAQQRLKKLSDDECKILFVGSKGNFPTSLPDDGEEIDLDKLGMSKYQQEQIDSRKFPEISIIPQLFHSLPLEEFAANTVIINKDVFLQQLDSIDNAACSWISLMSGLSLNMFQGFRTEEDLLDYFKHQAYFDNVTVLASVIFNMSEDGSMPNHMTYKIRQNASFTTTTNLVRSRFWFPGPRNWGYGYYQFGFVWIQDVLERAMISIYAGRDVTEPGSFIHQFPYPCYIQDQFLVSVVYSKAKLAASMCWNYILLTYVPYMYIAVREEAAHDHIPVWLKSLLSTTAFGLGAKYFAFYEEVGVGVQWFNIAISPVEDDEYSLLSVAIMMMIDATLYSIFSVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZD8</accession>
    <name>A0AAV4WZD8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_166291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016967">
        <property type="protein sequence ID" value="GIY87718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9362" checksum="5B94757F7BA08143" modified="2024-11-27" version="1">MTLASFRRFSLLSYMCRLFSKWPEAYPLVDISASSVASTFFGWFGPPLRIITDQGTQFEALTKFLGTVRHRTSPYHPAGNGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDI0</accession>
    <name>A0AAV4XDI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_419991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017646">
        <property type="protein sequence ID" value="GIY93247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10683" checksum="7F91C720D7C0D315" modified="2024-11-27" version="1">MEILCHIEDRECFGKKVEVLCVGSARMVETEMVSSISSEERQCEWSGLFPCHCEGLVFKNLVDIWACIAVSSVFVKKRQKRDERICFIEFMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF46</accession>
    <name>A0AAV4XF46_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_399061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017571">
        <property type="protein sequence ID" value="GIY92654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9441" checksum="ECBF319AA1102ECC" modified="2024-11-27" version="1">MTTLSQINDSADGNGLDEVLDSRIIQSLIGSFLQIRSNYSCHKWSFINPNSSLLFLRRRMASAARSSADREGRGSGEDYKVVLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHE0</accession>
    <name>A0AAV4XHE0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_200631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000261">
        <property type="protein sequence ID" value="GIY93360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12265" checksum="6CA2AF8E2C87DCB2" modified="2024-11-27" version="1">MKRKVIFLEIKIKISERLHNGERVTVVAKVYSLNEIVIEKPKTPLENASAGSSTNIFIRKRRCNGKYEKSIHDMVRENKKKIPIDTNTITNKALKIYEKAVSFILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIJ3</accession>
    <name>A0AAV4XIJ3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Titin-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_510921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000394">
        <property type="protein sequence ID" value="GIY94468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="632"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="753" mass="84407" checksum="4E668C72F733C7D8" modified="2024-11-27" version="1">MPQQIQPTSKKQDIKELEITEEKEVPSPVEVKDEKTVAKSPEHEKQEKIDQEEERIQEVTAPPKGLPEKTEPEKIGKPEELALKEEKKAPSPTEITEKKATPSAEVKEDKLAKPVKPESPAIEKEEVTIQEVTATPKDLPEKIESEVKEGKHEELLSKGKPKTTSPIEILQDKKITPSPEEVKKDKLVEPVKPESPTIETEAKEIQEVTEESKKDLPEELQEEKLPMKEKTKSPVKEIETHKRRKIPSPVAVDETKKTVPSPEELQKEKLPVEEKTKSPDKEIETLKEEAKIPSPVAVDEMKKAVPSSEEVQEEKLPVEEKAKSPVKEIETLKEVVKIPSPVSVDETKKDVPSPEEVQEEKLPVEEKTKSPVKEIETHKEEVKIPSPVAVDETAVPSPEEVQEEKLPMEEKTKSPVKEIVTHKEEAKTPSPVAVDETKKTVPSPEEVQEEKLPVEEKTKSPVKEIVTHKEEAKTPSPVAVDETKKTVPSPEEVQEEKLPVEEKTKSPVKEIETLKEEAKNTFSIAVDETKKTVPSPEEVQEEKLTVEEKTKSPVKEIETLKEEAKIPSPVSVDETKKVVKSPEEVQEEKLPVEEKTKSQSAGRKLPVEEKTKSPVKEIEALKEEAKIPSPVAVDETKKAVPSPEEVQEEKLTVEEKTKSPVKEIETHKEEAKIPSPVSVDETKKVVKSPEEVQEEKLSVEEKTKSPVKEIETHKEAAKIPSPVSVDETKKAVPSPEEVQEEKITCGRENKISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK87</accession>
    <name>A0AAV4XK87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein assembly factor 3, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaaf3</name>
        <name evidence="2" type="ORF">CEXT_484621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017827">
        <property type="protein sequence ID" value="GIY94823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044458">
        <property type="term" value="P:motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039304">
        <property type="entry name" value="DNAAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028235">
        <property type="entry name" value="DNAAF3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 3, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22118:SF14">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14740">
        <property type="entry name" value="DUF4471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein assembly factor 3 C-terminal" evidence="1">
        <location>
            <begin position="44"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12618" checksum="D9241501357D6A4A" modified="2024-11-27" version="1">MFLEILGNTYIRASTASYIENASMDILKSLDRSELNSGTLPSISTTHMKQKEIDELVKIFMYLKNKEMSCDIGKAWENALRSFFGQRFDSRKNLLTIISIYEAGRLQYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK93</accession>
    <name>A0AAV4XK93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_444381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000482">
        <property type="protein sequence ID" value="GIY95087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9506" checksum="E350FFC4E661F2D3" modified="2024-11-27" version="1">MGDIPFLNCRHISPDAIGLLRENKFISDASGAICFVLGKQSYLGRIVTPSTRSFCGSRVLCCLDESHFGQRGSLKLNTEFEVHENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM70</accession>
    <name>A0AAV4XM70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000477">
        <property type="protein sequence ID" value="GIY95040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12846" checksum="478CCFFCC625908E" modified="2024-11-27" version="1">MYREIKHSQCILKEQSFASLQNTSPLHLCFGKGLLGKAGNWIIITINRYMLPKGIRKYTRRYSPSLSLDKTWEEHGTAELHFWTCFCNQSAIDSRHIFILWCRGIKHTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQ41</accession>
    <name>A0AAV4XQ41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_279891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018023">
        <property type="protein sequence ID" value="GIY96260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQ41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9911" checksum="179340179E40526D" modified="2024-11-27" version="1">MIFVRESAKFIGSDKAHLCAGTGLGRELPKNSRVKGLRHVSAVGRRGYISPGFIASSRYDIAPLHVRDGRGRKEVTRPAGHSTVSVWPQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTI1</accession>
    <name>A0AAV4XTI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_223481</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Lipid-anchor</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000930">
        <property type="protein sequence ID" value="GIY98466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY98466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="191" mass="22108" checksum="63072351D03CDB68" modified="2024-11-27" version="1">MDYSSINPNNNEIFNHVTIAIVGQWECGKTSLVHAYLRDRAHLCRMQVIAYPPSCVFIYRFIQHDTEMTILDVNGLEAIVWFGRLLSHYSHAVLLCYNVDDRNSMFYLHAVFREMRRVEFDMVSVHFILVGTKRDLRQSGMPGITFEEGEDVKHDLKFSMFFECSSLDTSSVDRVFNHVIGLVLGYVDAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVD5</accession>
    <name>A0AAV4XVD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_569701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000891">
        <property type="protein sequence ID" value="GIY98165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="16812" checksum="942CEBB4119187A8" modified="2024-11-27" version="1">MDFASLSQDDDDFHQKNKTQKIPTGATKKTKTKTTRESKGRFPPRAQHRNDVQMDVVEKRKRSRVIEGSHVVPTRPDAAGDVEGVSLIRLMMSPLPLGMERKQLDSLRFTEDGGLNSVVVVCARVAVVPGCRHSVVGESMQMDACVLLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XW37</accession>
    <name>A0AAV4XW37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167223_1</name>
        <name evidence="1" type="ORF">CEXT_85021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001035">
        <property type="protein sequence ID" value="GIY99352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XW37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="490" mass="56870" checksum="EC65C3FE88BBC130" modified="2024-11-27" version="1">MVSKLSEICIKRISDNLVGDVWLRSQHNPFAKMPAKVVDMIMKAMQHPYKLPYPCISQLSLLISSGQLQCLDLTMHRGCPRHCHRDEYDEMIKLLTRDACKNLKSLTIPSEYNKGMSETIPKLLENCHQLEQLRTDNFFHLGALTLCPNMRSVKISYCKNCKTMFDSSWSIPEFQQFLKNMEVFDVLRFQNGSLLYDKIAKILLWGPKLISMGMIDTCIALDYIREKVEKRQFALKRCCWGKQYDDGIADQCFPSYGRRYPKIIKNSALSCPMVEELVLQVVHQDCLQHLRHLKQLNVLILKFSRFLKDPIPALLNVLQEIGPQLKHLSVDTFITFPVNDICRLCPNLESLGLFGCASVSEPVETCESLRHLQRLYTTIVDEKSLIFLLENCVGIQEMIINDADCFDDEMLDRVLQKNMFSKLKTLYIQRGQVSERKFVEFLETAQQLENVSTRDILFHKILYSKTRFFSNSVIANKPNFFENLLDQSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWL1</accession>
    <name>A0AAV4XWL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_715521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001057">
        <property type="protein sequence ID" value="GIY99531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13207" checksum="C4A5C0C87E673001" modified="2024-11-27" version="1">MSVGPLSINVFMTSQELLIIAGDIKVIRIKLCFSFNATGITYQLNLLTYDNAFPHSRPSHKGILMKCKCFCSISSKMYPPGVVILYFITILVISLFKYLKEVLTIQCLKDVLIIQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ62</accession>
    <name>A0AAV4XZ62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018400">
        <property type="protein sequence ID" value="GIY99241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10571" checksum="110999D75D6D5353" modified="2024-11-27" version="1">MQIIIFPCGDILDYLDVVLKFWYQYYPRVDTVHICKKQGSTVSASLREGQTSNESILCERGCLNLLSAMRRTFHSNDRQLYKAAVILAWGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZG5</accession>
    <name>A0AAV4XZG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001048">
        <property type="protein sequence ID" value="GIY99434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14403" checksum="EAFCAEFB2D988E01" modified="2024-11-27" version="1">MKAVAKFRFVTGQDCLASHLHRINGLEDLCCRHCNFQTLMNCAYLQRCPAPSASSFCGSIIGWLGAEWVHRLSSVAICYFILFGSAWLQLCLLYPHPTGNKEKKKLKTTMVQKVCIVNSREQCTTFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y075</accession>
    <name>A0AAV4Y075_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_421171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018430">
        <property type="protein sequence ID" value="GIY99543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y075"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9742" checksum="6080FBB60B23E2E4" modified="2024-11-27" version="1">MKYKRPSSDEEEKEKKIQFRSLFAGDENAARGIFQCSFCHRNHPSYANRNWVDLRWDLAKDFCPSDFFPSCCSSLLPANASVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0N0</accession>
    <name>A0AAV4Y0N0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="3">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RECQL5</name>
        <name evidence="5" type="ORF">CEXT_702131</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01001232">
        <property type="protein sequence ID" value="GIZ00973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0N0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000614">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF152">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="42"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ00973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="421" mass="48172" checksum="7DE911AE0759E18A" modified="2024-11-27" version="1">MDDILALLKLCQPVAIFKTSCFRPNLFYDVIFKETLEDPYADLTQFAYSALGDHWEMSPPGERGCGIIYCRTRDGCEDLSHRLTKLGLHTQPYHAGIKPGIRQETQNGWMDGRIPVIAATVSFGMGIDKPTVRFVAHWCVSQTVAGYYQESGRAGRDGKPAKCRIYYSRKDRDTILFLLKKDENSIKTKSGRMKVGATIKSFNTMIKYCEESVCRHYLLAREFGDDMPDCRKHCDVCCTPKIVAQKISKFKSIFLGSKIKYKENNNFSDLYGGGREGVQQETHEYQREDNSNQEKEAAAALSKLISDEFSKRRGSKEKSEKYVKTRSTKVIQPSLKKIPEVSVVMREKYFDKLVEEIKLHIKSCNSNQHCPNLSDSDIKQCASDFEWNSFNSKGNIHMYRREIVNLTKSLREASVKLKFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y160</accession>
    <name>A0AAV4Y160_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001171">
        <property type="protein sequence ID" value="GIZ00544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y160"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="285" mass="34838" checksum="BB436B9C8AB16D67" modified="2024-11-27" version="1">MIKYQKEKDQSDQISERTDQTSERKDQIRSNIRKKRSDQIKHQKEKIRSDQTSEKKRSSDQTSERKDQIRSNIRKKRSDQIKHQKRSDQIKHQKEKIRSDQTSERKDQIRSNIRKEKIRSDQTSERKRSDQIKHQKEKIRSDQTSERKDQIRSNIRKKRSDQIKHQKEKIRSDQTSERKDQIRSNIRKKKIRSDQTSERKDHIRSNIRKKRFRSSQTSERKYQIRTSQTSERKDQIRTSQTSERKDHRTSQTSERKDQIRSDQASKRKDQIRSSMRKKKIRSDQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1W4</accession>
    <name>A0AAV4Y1W4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_726971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018656">
        <property type="protein sequence ID" value="GIZ01333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1W4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044022654" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16876" checksum="ED59A7439CA16F89" modified="2024-11-27" version="1">MLGLKRDISLQLSLLLVAVVRIVGDDVSTNHQRVECRRQQPHLENLNKQPPHPPILEETKISSEGLPLDTLTRPAGVGIRGRDYKCRKCCSAILQLSLLLVAVVRIVWDDVSANHQRVERNGDRSGDNFRRTYYKELYFRMTIDIGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9T2</accession>
    <name>A0AAV4Y9T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_478951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001523">
        <property type="protein sequence ID" value="GIZ02919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12808" checksum="26CF4B44AA6D08E8" modified="2024-11-27" version="1">MEGISVGLFVFEQIHSPSICDDSRAPFYNISSALKWRMDGISMELFVFYELWCSFAHCCTGPDMEIDVRHTSLVTDIRCLNIDHAEYECPNPRITPKNCLLHCVPHWITIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCG7</accession>
    <name>A0AAV4YCG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_785191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019124">
        <property type="protein sequence ID" value="GIZ04703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24073" checksum="B7A0B017FC1FD5B3" modified="2024-11-27" version="1">MERKNPNLNYSSTPLLMRFFSFFNYALQVHRPQLLAIPSAKKTNLILIIAGFNLEPNHSPFGEARKESQILLQDNNRFPGKRKQRGVCAGPPISSYWRFSSKKTNLILIIAGFNLEPNHSPFGEARKRKPNLTSRPIIGFRDKKKSEGVCAAGIHYESIGHTKAISSYWRFSSKETNLILIIAGFNLEPNHSPFGEARKESQPLLQANNRLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCH4</accession>
    <name>A0AAV4YCH4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prokineticin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_318111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019013">
        <property type="protein sequence ID" value="GIZ03925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023569">
        <property type="entry name" value="Prokineticin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06607">
        <property type="entry name" value="Prokineticin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57190">
        <property type="entry name" value="Colipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043551347" description="Prokineticin domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Prokineticin" evidence="6">
        <location>
            <begin position="15"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ03925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="14325" checksum="9D383FCEBC404353" modified="2024-11-27" version="1">MNYFLSAIFFSGVLAVVSAQACIEQAECDASQCCAGVPPFGGLCQNFTAEGGKCHLVDRIVPIFGDFYVGPCPCAEGLVCIQQGKHKNNGICQLPPTTAAPTAADDSAADDSAAADSAADDSAAADSAADDSAAAAADESVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8F2</accession>
    <name>A0AAV4M8F2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_804811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019465">
        <property type="protein sequence ID" value="GIX68163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8F2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8091" checksum="01F861F33271D89F" modified="2024-11-27" version="1">MSCVISEKSFGTWQGGWGCSGICQPPPLVDESSMRPSPNFISKALEARRGFRANSLKGILRLYLCFCKEEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLY2</accession>
    <name>A0AAV4MLY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_241435_1</name>
        <name evidence="3" type="ORF">CEXT_200921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019858">
        <property type="protein sequence ID" value="GIX72567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX72567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="289" mass="32541" checksum="A6E365A781D8877F" modified="2024-11-27" version="1">MFELRLRVLKIYSMSSLPQGWHGIPVPTRNSISSSTISAATPVSTTIRKKWNSPLSSEVPRSKLPAFKPSTLRLHKSPINGILPTRTNSKIPSTALKNDVATCPTKPSPIKQLQNEIAKLKKVELTTMKTENSILKVKVRRVDDENVQKSRQIEKLKVELKAAQKVDSTSSKKNKDSDLLLLRQKCLRLEGALKEKDLALNTFRRLNNEASLKLEGRASRNSLTHFEAGDADDSNENCRTIKKNTSAKTSFSRTSHSTKTEVSKLREMIHKLEKENQELQQLAKDKKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPP5</accession>
    <name>A0AAV4MPP5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_110611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002500">
        <property type="protein sequence ID" value="GIX74348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969:SF69">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969">
        <property type="entry name" value="RING ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX74348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13334" checksum="DBE3D55A989BEC3C" modified="2024-11-27" version="1">MDRAERLASLRKRPPPVVIKRRTRRKVDYPEPKPGEVMCSICLDTLRRRKMRALPCEHEFHELCVRDWLNSGDPYWFKTCPLCRKPLHNFGKNSSFFNELLNLLRVIAHESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N487</accession>
    <name>A0AAV4N487_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_48611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002834">
        <property type="protein sequence ID" value="GIX78387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N487"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9850" checksum="57AF053EE08E2D7E" modified="2024-11-27" version="1">MNSQDDEVKKTSKVQRNKDYIRDVPGKTPPLKHHASEHYQIGLLDRRSAQVTMRVCSAAAFPARGIRYRINRKMAPEDTWPSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N538</accession>
    <name>A0AAV4N538_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_809201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002844">
        <property type="protein sequence ID" value="GIX78524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N538"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8716" checksum="7B864A75C669CB61" modified="2024-11-27" version="1">MLSSGHLCYRPVVWSAPAISRLRRSNTLWGDASTKRRFRLRDRRALPKGQLQLYIPASQNNPGPETSVAGGEGSPVTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9W5</accession>
    <name>A0AAV4N9W5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">spop_24</name>
        <name evidence="1" type="ORF">CEXT_709781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020682">
        <property type="protein sequence ID" value="GIX81478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9W5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17154" checksum="862B1CD36D0B40E7" modified="2024-11-27" version="1">MYFDREKRSCEEFVCFELKTIDTSVMFTEMKLFLLDALGNTIVSIQDEFWHDCAGNNKPFLLFSKSKLMANQSLYLPCDVLTVRCDSAISTGIVMETIEKLYLGRCGDSQATSTDVDCTDDEERLTFSKKVLKEDLKSLYSDGYRSDVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NC93</accession>
    <name>A0AAV4NC93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_453541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003220">
        <property type="protein sequence ID" value="GIX82273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NC93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12948" checksum="04FD635620986B6D" modified="2024-11-27" version="1">MMNVPLIFRCRNISNSKSRRENKIKKNTMPINELQNTILLFGVYNSLSVPGKKIFSTTCSHPQSQARIRHDRSFETFQISRKLQHLRDILELRLLALFCENLSPNKTRMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCZ2</accession>
    <name>A0AAV4NCZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_613771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003231">
        <property type="protein sequence ID" value="GIX82358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10837" checksum="29B511140D9F9FB0" modified="2024-11-27" version="1">MNEDSPVSVTVTSQRNANFSVFAVRLTLVELGSFFCQRSSLSACHFAFCLPEEEDVYRTKQPAQSYVIILLKCGTDLFRAASNRNAFRRIVRFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NI35</accession>
    <name>A0AAV4NI35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_606901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003429">
        <property type="protein sequence ID" value="GIX84467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NI35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX84467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="285" mass="31585" checksum="4B8658C995583BA5" modified="2024-11-27" version="1">MTFEYEGSRSIFRNLFCLPLSWFCFFWTTVFIGFGIMFSFSKESVIKFFTCTVLRRNSMSERLPSANEPPEYSDEAASFNYYRPTPLIPKSPPVPIQKKETYDDTMTLSSSPPTGFKIKRRQPPPRHQCEAPSPQTSFQNTPEDIFYMSLDETSKKSRPTAQNKPVAKSRSPVEYASVGNESAGKSGSATEYGSIGNYKSAVKFGPVVEYESVGDYESAIKSAIKSGRVPVSGSSYGSGYLEGDWSHEASFGSGSSGSVYDETVSSSFEYGFLIESVTEQPRPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIW4</accession>
    <name>A0AAV4NIW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_67594_1</name>
        <name evidence="2" type="ORF">CEXT_185361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003426">
        <property type="protein sequence ID" value="GIX84428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="15154" checksum="8AAE89C4CE56E7CC" modified="2024-11-27" version="1">MTPIQIASNVIEKLQEENRIALETLRKCQSNIKYLERQLVEKEQLIKILEDRYRTGTNSYLEISNKQKELTIKHLELQIQKLLKENKKLEQQIADIQYDICAKCEMKQFFGIPIDNKPCYKNQRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNX7</accession>
    <name>A0AAV4NNX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_751691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003563">
        <property type="protein sequence ID" value="GIX86089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15471" checksum="C81491625866DB5E" modified="2024-11-27" version="1">MPLRIKLVAGHRVLPPPHSTPRPRSLSPLITPTKLGPFNVTPLRHTPSSDCGPNGPWQRRLYAPCCNGAAFLALAQAEYNKAHPYTTRFGKRRVMERCDRGSQSPGQLAQQAFIMMGLHSRVRDGTTVCRVAKRTKAWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ27</accession>
    <name>A0AAV4NQ27_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_116685_1</name>
        <name evidence="4" type="ORF">CEXT_577081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021099">
        <property type="protein sequence ID" value="GIX85865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX85865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="24857" checksum="0637E084EF81C29E" modified="2024-11-27" version="1">MVIDTPVFNCNTLPIVVALNMPGCPSTRFRHSISTRIPCIIRRFDRDCCGYLKLDQFHDLLNYYGASMSKPLLRRIFADADTNSDGRLSFSEFLHLWHHVADHEDLFLSSFGNRDMIEIARRYHLHPPVSCNHCGELREDLFGRITSHGRSDEGEDDERGPMRDIDREHEAGSCTCGTFGKVIPFIQRTNMGTADDTPTDKLPIFSSNRGASAASEYGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ65</accession>
    <name>A0AAV4NQ65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_54021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003646">
        <property type="protein sequence ID" value="GIX87055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16109" checksum="772FA63ACC82B2EB" modified="2024-11-27" version="1">MIPKARAPANWPSGHRKSRKGLKFFCTAHLSSTATMRGLISFLLIGSILLTYVLSETTDEELEAEEAFNQMLDDLDTVESEMDEEEASLEVMVANLSDHVFLEVKIAHRNLMHVVEVKYSKISAGALQKPMKKSVLASKLIFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTE3</accession>
    <name>A0AAV4NTE3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_10961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003624">
        <property type="protein sequence ID" value="GIX86879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTE3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14244" checksum="2E2233E4C3117B26" modified="2024-11-27" version="1">MKQTSSGQLFPALSPSVERVVNRIWKNEKASFIGRAALYSRVQFLWEGNPPLVSVNVFARTDKDLIDSTAERACNRRVNRKEMLSDLIILSRFDFVLSFCDSRMAAFSSVNATFSTLVYDTTAPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUT2</accession>
    <name>A0AAV4NUT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_577621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021242">
        <property type="protein sequence ID" value="GIX87515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="32" mass="3421" checksum="F754075ABEE74CE0" modified="2024-11-27" version="1" fragment="single">MFSSSRQEQMAAALQSFGSLKQSVGFAQGRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYR5</accession>
    <name>A0AAV4NYR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_735831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003803">
        <property type="protein sequence ID" value="GIX88908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="8858" checksum="76F0134134BE3860" modified="2024-11-27" version="1">MNPHLVEKKVEKAERLRPCSASPVDSTLLVAVCVVSSLPAPLSPSSMSCRGDPETLSSALARKQSAAMLRNGAATKRMESRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZS3</accession>
    <name>A0AAV4NZS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleoside diphosphate kinase 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NME7</name>
        <name evidence="8" type="ORF">CEXT_570951</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021395">
        <property type="protein sequence ID" value="GIX89144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04412">
        <property type="entry name" value="NDPk7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000004">
        <property type="entry name" value="Nucleoside diphosphate kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057579">
        <property type="entry name" value="DM10_NDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037993">
        <property type="entry name" value="NDPk7B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109:SF2">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25364">
        <property type="entry name" value="PH_NDK7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DM10" evidence="7">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX89144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="357" mass="40582" checksum="ACD7481B66F3C636" modified="2024-11-27" version="1">MSDERYRFLVEWFDPTMKIKRKFMLSYFSSDGSVEMYDLLLKKLFLRRIQCDSVREEDLFVGSIINVLSRQLYIIDFGDRTTASKFTREVESTIFIINESGFTYLGRIISILEDNNLLINRGKIIDKEKSGFNASSLSESLKKLFLILEVRGQSARSIARKLVNPESPVERPLKADLRDLSGHCLAPTDDRTAETEIKIFFPSSKEVHCNTAVYRNSTCCIIKPHAVREKIVGKIIQDIIVAGFKMSAFEVVTFNLATASEFLDVYKGVVAEYKDMVSQLMSGPSIALEITKQNPSNVFEEFRTYVGPADPEIARKIRPGTLRANYGHDKIKNAVHCTDLPEDASLELDYLFRILPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2S1</accession>
    <name>A0AAV4P2S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_274411</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021574">
        <property type="protein sequence ID" value="GIX91321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX91321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="376" mass="42232" checksum="833EC26022231E3F" modified="2024-11-27" version="1">MHNLISTWLLPRTKQKGNTTVKPTSKCYQSEKDLVRQSAIDLSDTWLSLGVTKDNLSRFGHKAEDLIIQCTYNSNDCWSNGTSYRVDITQVTSPIFGLCHTLSVKNNLTDQPATVKRGGTTQGTTSSDVEHRKVNVLGLDIFRIRREAAGPSSGHLPHTAERGIIASPGRSVHIGVRRVGMRISLLLNQCDPQATRFTKLLPGNEGSCTEHFQDSQIFERLKIMDLDFDLDSLKYTYEHCNTLCQNTMLFSQCQCLDEQPTGTARAKWKFCSPCNKTEAKCRSAVIRNFTDVGNDCDDLCKPSCKSVRYDISLSKADWPNLNHQQFVMNRSFDQWNHIPEALGLLGAFEQDDANVTDFVNDTFSGYSTCLSLIYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PB48</accession>
    <name>A0AAV4PB48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004214">
        <property type="protein sequence ID" value="GIX93200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PB48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10411" checksum="43301AED71E49C92" modified="2024-11-27" version="1">MLSLKEKTPVKQTFRVCENWLGNGSRLSVTTSETEHFSQWRKKEANIEVQDQGEKIPNSKLFFISAQDRVLHFSVRKISVSAKNSITITLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCH4</accession>
    <name>A0AAV4PCH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_294851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004472">
        <property type="protein sequence ID" value="GIX95102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12339" checksum="8C1265715C258070" modified="2024-11-27" version="1">MERAQNGGPDMNAWHEGGGTTGQTFHCSMGFVDFKLGFWLVCSLAKAVRHRGQPCCYLELIEKFIRSSIYGSCLMCVCLLQKEWIKFLVGYLIFFRLHKRLISVINW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PI09</accession>
    <name>A0AAV4PI09_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_738881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004421">
        <property type="protein sequence ID" value="GIX94737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PI09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11314" checksum="C6D26A47FB6EA42E" modified="2024-11-27" version="1">MITWLVNHLTDKYFSRILQPVTLYRQVRLRVHQNFAALFMVGRNAVISMLNVRIDILCSVLFLGQSKFFRRNLPQFEPLFLCTFRTAKSNSTANYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PM15</accession>
    <name>A0AAV4PM15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_438421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004871">
        <property type="protein sequence ID" value="GIX98154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PM15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="19" mass="2063" checksum="BAB96BAF73DBEB56" modified="2024-11-27" version="1" fragment="single">MASGASQFQECNRGFAPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNH2</accession>
    <name>A0AAV4PNH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclin N-terminal domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Cntd1_2</name>
        <name evidence="1" type="ORF">CEXT_389231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004776">
        <property type="protein sequence ID" value="GIX97409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21615">
        <property type="entry name" value="CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21615:SF2">
        <property type="entry name" value="CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17491" checksum="3AFB0D1E4433B155" modified="2024-11-27" version="1">MSAPILTEVKNIRKIPFDLLEESLFYMAKRNQERIRSAISLNWNGHLTSLNLSSTLASIFKLEKSVKYVALEIYERFLAYHVLELRQSVKDRQETDRPLSWEVIEERITEQTVLRVLTSIQLASKLSSHYDHVLPTQVAEFLEKSGGKSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUK3</accession>
    <name>A0AAV4PUK3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_195601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005262">
        <property type="protein sequence ID" value="GIY01108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUK3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18791" checksum="83FCE1EBD70C7C8A" modified="2024-11-27" version="1">MIERRRHIFAEYLSHCHLKSTQMFNSASPCGMPLIRYRQKFKRHLNAESKFHLIEMTSEKYRHGGDVNSEADSSCFYYITVSGSPWRRQTFETVQKMFLSPSHAGSFRGLVMKSNPVNSTSGTGFLSLTEFWAAFCRSGNFNIERRLFYWGWKFCRGQNGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWZ2</accession>
    <name>A0AAV4PWZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_12131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005408">
        <property type="protein sequence ID" value="GIY02093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13403" checksum="1121FAFF2EFF5DE6" modified="2024-11-27" version="1">MFKADRGLATPALDPEHHDRLRLVQAAEWFNIVVKFNNLKWMTCWQITVDLKTNDKTAFKYMCSLFFRFKANPIIASFFCGNTQFPDQPVPVHFNSDCMTEFKTLATLIRLHHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1Y7</accession>
    <name>A0AAV4Q1Y7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_254691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005420">
        <property type="protein sequence ID" value="GIY02192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1Y7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11427" checksum="2C537932B80B442C" modified="2024-11-27" version="1">MAPKTTALANRSSWPLSSGSTRLSDCSKVHGNCNNVIISHGSSDSLLPVTGVRTCFMLKERTVEPRKSKIEARRKCAGKQAVQGKSAEHRGHVELIGVHKEERSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q940</accession>
    <name>A0AAV4Q940_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_400371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005763">
        <property type="protein sequence ID" value="GIY04872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q940"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="15697" checksum="0076D32895FA2A51" modified="2024-11-27" version="1">MNALALQLGLPFVTGMRLEESISLRVGRYDSITALGETPIGGKASREKRNCPSKQETGGKTFHTIMSRAYFIENYLNPRFSRRTFSNSATLLTPDRHICLEGRREGGERADPLPSVVPKRSCVQIEFSLGNKAANHGQCALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDM5</accession>
    <name>A0AAV4QDM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_365281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005952">
        <property type="protein sequence ID" value="GIY06387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14776" checksum="ABCBB62C0002FE51" modified="2024-11-27" version="1">MYQEQNGDTIYKFKDKLKEIVLLCILYKTNIYVRNLVICIFLQAIKDDDAVAFLPCNAKIRRLNEFSKTKIRYHKMSEDTQKPVINSHFKYFFQNRFPTAEKNPTIFFMDALSSVADRFDESER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDR5</accession>
    <name>A0AAV4QDR5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_797011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005963">
        <property type="protein sequence ID" value="GIY06471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDR5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8551" checksum="980BA104493F26A7" modified="2024-11-27" version="1">MSCVESDEFPACATLMGPENGRLAVAVGYFVSGFIIDGGMVVGLGVNSIVTYDLSNMQPRTTIGNKTSSSSIYFKLWSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJW1</accession>
    <name>A0AAV4QJW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_470301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006258">
        <property type="protein sequence ID" value="GIY08502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11086" checksum="484534213CD86937" modified="2024-11-27" version="1">MDGKIKVTRDAKRRAKRKKDSKKKKKSKLVAVSGFRGDVFPAEVRYVSAMTARIRFVQQLLMLGPLEGQLFLEWDIVSESTDLKENGTNVGGKGLRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNI2</accession>
    <name>A0AAV4QNI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_810611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006420">
        <property type="protein sequence ID" value="GIY09717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14967" checksum="D7A878882475B31B" modified="2024-11-27" version="1">MAKKSHSLKKNPCRTARVVPGGPTDFQGIQEVGVSIIREVTHGAEDCRGNTNSLRRKPQSSFSDSLKKPSKKADQDEKLRKSHYQHPMTCLINKVTSSSWVVKILEINFKIAQVDTCKKFNFYWFNLSQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QR44</accession>
    <name>A0AAV4QR44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc finger protein 585B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ZNF585B_3</name>
        <name evidence="12" type="ORF">CEXT_670681</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006725">
        <property type="protein sequence ID" value="GIY11940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QR44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24376:SF250">
        <property type="entry name" value="ZINC FINGER PROTEIN 770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043988578" evidence="10">
        <location>
            <begin position="19"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="331"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="476"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="532"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="587"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="615"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="254"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY11940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="640" mass="74586" checksum="F3DA373E760541C0" modified="2024-11-27" version="1">MGILFFYIPLIISALINALDDNNIKAFVRKNTLLKHYREHTKELGENLERFEEEKAKYLAKKYPNQVITIENTDNVLNESQSIQQAKKFQNQILNLDGSYHNAILDIYPGLADDVEQNGDHSVIQNLDSNDIIITNMDSNTVMVQNLDPNSIVEHLEPQPLVHNSFPIPLPSHEKERHGCTICGNCFSASSSLKRHMLLHKNEEEQREICQFSCAICNAKFIRKISLKIIIEFIKRHKTQAHGNGKKQSVFSKDINKKSKTKPDFNEQKQTPKKKLFVCNICGNAFRDKQEYETHKKGHSEKAVTCEICDESLAPDDYDVHMLMHNEGKMHTCRVCSQSFMFKDDLVAHSRTAHVEDQPFECTICKDRFKFKSDLRQHKQIHNQKTNSRKTYHSDDNVSLKSELASNNTSSCKKKSNLCKICGESFASKTELNVHKELHEMEIDQELFPCKFCNEKFQSKSELSDHTVSCSKKKPHLCKNCNQRFMTKIEFLEHKKIHSRRQPFICKVCNEGFREKNALDEHKKIHNTIPTYPCNICDKIFMQKETLREHKLSHQDEIAYICSVCNETFENKADFKAHRETHDVIIHQCKVCFETFSIRKELKKHYLKHILERPNLCRICNANFEQWGALRSHYLSHTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R976</accession>
    <name>A0AAV4R976_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_393521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007402">
        <property type="protein sequence ID" value="GIY16707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R976"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326:SF1">
        <property type="entry name" value="HTH PSQ-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47326">
        <property type="entry name" value="TRANSPOSABLE ELEMENT TC3 TRANSPOSASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11755" checksum="A4300ED38528146A" modified="2024-11-27" version="1">MKVKYLHDLQYFGQQLQQHEANNAFTARILWADEARFTRDGVFNSHNSHMCPPPILMPSARRDIRAAGLSLARHWLDIEYAGHWIGCRGPVSWPTRSPDLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9U1</accession>
    <name>A0AAV4R9U1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Myosin heavy chain 95F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">jar</name>
        <name evidence="7" type="ORF">CEXT_557791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007438">
        <property type="protein sequence ID" value="GIY16902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9U1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030048">
        <property type="term" value="P:actin filament-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF745">
        <property type="entry name" value="UNCONVENTIONAL MYOSIN-VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0518">Myosin</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043752776" evidence="5">
        <location>
            <begin position="22"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="6">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY16902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16274" checksum="7CAA7D969B33215F" modified="2024-11-27" version="1">MKGKIFILLWLLFLHLGNVSFEDNPDDCKGGCRLAPGAAEILLIISSLLGVDSQYLRQSLLSRVMQTSKGYVVIFNFGNIFSCIRVPLKVHEAQNARDALAKALYSRLFDFIVQCINKSIPFSSSSYYIGVLILQVLVCLNASFIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RD72</accession>
    <name>A0AAV4RD72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_780311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007691">
        <property type="protein sequence ID" value="GIY18901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RD72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12277" checksum="D7F972A4AE11DD27" modified="2024-11-27" version="1">MYCRMVSGKKCPQELRTIDVTLARLLNERGSRQMDRTCWKNVFFFQEWVFRKEMSSIKNDSWRSRKGRRLLNERGQDRWIGHAGKCILLPRIGVSYRVHSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHK1</accession>
    <name>A0AAV4RHK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_38521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007872">
        <property type="protein sequence ID" value="GIY20386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="19775" checksum="1219B3606144365D" modified="2024-11-27" version="1">MAGSKFYLSTENPYKCHCFEYVTEQRKAGRQIPAFSFCYSEVDVYSSNGFPEAARAPYTKPRKKTAIMRGINYGESTNGYNTKNKNNHFYDLFCKRVAISADDAHRVAPHQRAPVRSQPRYKPTSFVAKGSISPYQKPTVLSEISITAFAVNLPLQVCLYREPARLGVYVPFHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RL16</accession>
    <name>A0AAV4RL16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Battenin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CLN3_1</name>
        <name evidence="7" type="ORF">CEXT_548771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007925">
        <property type="protein sequence ID" value="GIY20718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RL16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY20718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8404" checksum="73E20E8C2A5EE06C" modified="2024-11-27" version="1">MTENEIATKQIEEINSELDDINSYPDIPEEKKGRIRNLIGFWLLGLCNNYPYVIMLSAAFDILYPKNGDAPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RLQ1</accession>
    <name>A0AAV4RLQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_181708_1</name>
        <name evidence="4" type="ORF">CEXT_717441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008077">
        <property type="protein sequence ID" value="GIY21974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RLQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY21974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17037" checksum="A923D7B673A383D6" modified="2024-11-27" version="1">MCGRYLLNGTVSQCLTVKEALSYRSNNTDDSDTLHEGDVVEVYLKKYKYIEEILIPAAACVVGLVFGNVAIILLIQKIRKQRKSSSSHHNGRSSSVPPSGSSNTQVPQTLHVPTTVSTDTAIPSITRKEAPPIPPKPIIHPLPIVRQAPRVLMTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNN8</accession>
    <name>A0AAV4RNN8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_294591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008328">
        <property type="protein sequence ID" value="GIY23873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036084">
        <property type="entry name" value="Ser_inhib-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002919">
        <property type="entry name" value="TIL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01826">
        <property type="entry name" value="TIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57567">
        <property type="entry name" value="Serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044011244" description="TIL domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="TIL" evidence="2">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY23873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7436" checksum="BF0C118C751847A7" modified="2024-11-27" version="1">MKVFLLVCLMGLAVVGAKGQSKNHRCPKNAVWDQCGIDCPKTCQGQEIKCPLKCRFGLRVRGGLRSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZK1</accession>
    <name>A0AAV4RZK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_815581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008844">
        <property type="protein sequence ID" value="GIY27713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12079" checksum="812AF350CE26FBCB" modified="2024-11-27" version="1">MTAHQIALKELHANHIAKRSARVNIKSNDTKSSYQSEIRHLSKHIKLRHFEVIRKSAILFKLSDLTCIDFSIQHIHEELDLHVSRYDDENVPEDLIDRIGDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2J4</accession>
    <name>A0AAV4S2J4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_798821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008813">
        <property type="protein sequence ID" value="GIY27406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2J4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9690" checksum="DD2781BA248E84AF" modified="2024-11-27" version="1">MHLLCCGRKKHRALALRNRLAVTSLHVSALIQRRGSPLDKNRSDFPIPLLFYTMPRKERKKRCHPCDNIKQPSHVILIVLPVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6F9</accession>
    <name>A0AAV4S6F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein giant-lens</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aos_1</name>
        <name evidence="1" type="ORF">CEXT_578021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009006">
        <property type="protein sequence ID" value="GIY28949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021633">
        <property type="entry name" value="Argos"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11581">
        <property type="entry name" value="Argos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11481" checksum="788FEC64C02A559F" modified="2024-11-27" version="1">MTSDKKFQQRFTANALRTRSTTYISGHDGMRCRRKEPCRLFTVRKRFPVEEVTTSTLCRCPPKTSCPAHHTEPYVLADFDANRPRDGTRTYSGFCGTSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S944</accession>
    <name>A0AAV4S944_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_417951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009276">
        <property type="protein sequence ID" value="GIY30778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S944"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15390" checksum="7B65A4ECC3DD060C" modified="2024-11-27" version="1">MRSCGTAEVNNGFPLIEKRIEDYYAMVLNLCFGYPRGENRQKTKMIPNLAAAEIAKCISYAWRVQTSWEFYRENMPYKCNNLVKGSSGGMRSCGTAEANNGFSLIEKRIEDYYAMVLKSLFWPPLGRKPPKRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNY4</accession>
    <name>A0AAV4SNY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_435301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009722">
        <property type="protein sequence ID" value="GIY34097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10118" checksum="1A23A25A95701135" modified="2024-11-27" version="1">MPPLKRRYCSPGSSDTLSPDGDTILGLWRQEQCALKTLGRFCSNIHTKSAAQLRENFMEYFCSVEQLEWQGHHVLAQAVHIEFIFSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY04</accession>
    <name>A0AAV4SY04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_261901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010444">
        <property type="protein sequence ID" value="GIY39313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11488" checksum="74731DF3C6BC65C1" modified="2024-11-27" version="1">MRKWMGFLPIDLSAALFEAGENSIRRVLFPEKERGTAWKRASGRSVRGRCLYAIIAWKGVFFEQIIAFVLPKELFKTQRQRSVFKLLFELRTKALMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZL6</accession>
    <name>A0AAV4SZL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_409721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010324">
        <property type="protein sequence ID" value="GIY38566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8034" checksum="CE081C0875347043" modified="2024-11-27" version="1">MFDLSLGLSGQRVYGKKMCSGAVRLAGWGSRINKQKQMEALNILMAEAIVSFGPEWEILSPSLNTTPQLDYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T064</accession>
    <name>A0AAV4T064_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_781521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010273">
        <property type="protein sequence ID" value="GIY38222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T064"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10520" checksum="089F3BC27181309B" modified="2024-11-27" version="1">MSSGSFLYFLFSKILKSLASIPGRPYTSPSAMSGMWLLVFLIIQAGNLIRVLNGSFHGSARSDEPTCEELRTFWNAVSQSMRMNEFTNEIPHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2H8</accession>
    <name>A0AAV4T2H8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_568701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010463">
        <property type="protein sequence ID" value="GIY39429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2H8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12164" checksum="46C3D0B122D741D4" modified="2024-11-27" version="1">MEHGERQQIRLVHLNKRFQLKSYKTITHANSLRIMNLRSAQIRIVLEICPSQVREIPPVVRNTQTFRMALVCNENECFSYLVVIHANTETLAASFGRKAGTAIVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4Z8</accession>
    <name>A0AAV4T4Z8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_287951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010751">
        <property type="protein sequence ID" value="GIY41753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4Z8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11170" checksum="FC0D1FA374DCFF49" modified="2024-11-27" version="1">MVILLSVQWPAGGPFSSCGREYRWRVSLVLLAESWFRATYAHIFITILRGALLLSMSTTGWEYSFETTVPTASCWSHGLRASQLQPCSGFSNQLSATAGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCW8</accession>
    <name>A0AAV4TCW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">para_11</name>
        <name evidence="7" type="ORF">CEXT_394451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010922">
        <property type="protein sequence ID" value="GIY43044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0086010">
        <property type="term" value="P:membrane depolarization during action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019228">
        <property type="term" value="P:neuronal action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF288">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN PARA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="6">
        <location>
            <begin position="155"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY43044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="29214" checksum="667078AA5D57E900" modified="2024-11-27" version="1">MDRKSIFKALRAFRLLSLTSLFKSYQETVPLPMKNNSCIARSESVSNESLLHLRQFECNRFLGRHCRYRPTGSGEIFQMDWNAPEIQSSDLSESRMRRIELACTVDYRDRNRTIETQDCLPIFCHNIFPLCKQDCNFFRLFAAIRSKSSVLLRSKYFFSAVVVMILLSNCLLVVELNFSEEKLPIIEQIAAYLDKVFAGLFLLEMLLKMFAFGLKDYFSSFWFIIEFLNVVNIDFVYIEFYHFSNMTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGS7</accession>
    <name>A0AAV4TGS7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ionotropic glutamate receptor L-glutamate and glycine-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_65851</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011174">
        <property type="protein sequence ID" value="GIY44646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF38">
        <property type="entry name" value="IONOTROPIC RECEPTOR 100A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="12">
        <location>
            <begin position="95"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY44646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="27641" checksum="7177F0A8E99B1D8D" modified="2024-11-27" version="1">MVTLPETSVRFKEVKLTDYSYSVTLLSRIIQPTKVAPIRTFHELSGAVQSGDHKLYAMETQIPFLLDSLEDDLKALGRMKGKRRSATGRLRRQTLLQIVLEAQRIQYEIVVSKDISFGKALPDGNFTGMIGMVQRGEADLAGGYLIMNEVRSKAIDFSIRYLLEETTFRTPMPGNNKSNLALLQVFDGTTQLKSHRLGHELSRTVQSGDHKLYAMETPIPFFLDSGKDDLKNLGRMFVLNNWVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIS3</accession>
    <name>A0AAV4TIS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_790131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011354">
        <property type="protein sequence ID" value="GIY46015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7221" checksum="23D3F38D3F2EE5F7" modified="2024-11-27" version="1">MEGVGGEEGEVCKQCIPSRYEPGRAWPIEHSPSPIGYGTPPLPFHSSLPVSNTSGVYAVVKHSMRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMC8</accession>
    <name>A0AAV4TMC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_771411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011370">
        <property type="protein sequence ID" value="GIY46127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9912" checksum="A5847AE4EA5EBC61" modified="2024-11-27" version="1">MRNKTRTHMTTWTSINFQENLILLLLPKAKPMTELKGEGCMNYACGDPKLKHGIQQNLKEIPSDQYKIYLDFSPCVGGAGRIPKAFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TY00</accession>
    <name>A0AAV4TY00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_394061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012037">
        <property type="protein sequence ID" value="GIY50864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TY00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="13315" checksum="5EDC15560ED14F1A" modified="2024-11-27" version="1">MNRKLKKRVTMIKVEKRNNDDNEEEVEETSDNEEEVEETNQNKENESTTERYENRETIRDDKIQESKIIIADNESTEKCVIIWIQQKNMKSKYHYLQLKKARQRQAYHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1A1</accession>
    <name>A0AAV4U1A1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_248651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012123">
        <property type="protein sequence ID" value="GIY51525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1A1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13611" checksum="802C98939CDCA4B3" modified="2024-11-27" version="1">MEKTLSIWIDDSCQKRIPLDNDINKKKALKIYKHLKEHGDPLNSVNPESVAKNEIGGILEPAKSIGGKGFMDMVIEDVQGLLKEEEDDEADLMQMAPVTVNESDSEDSSTDENCEVNNYKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4Z2</accession>
    <name>A0AAV4U4Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_554851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012292">
        <property type="protein sequence ID" value="GIY52811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9151" checksum="6B02CAAD35AD6358" modified="2024-11-27" version="1">MVLDTGRFSPPSIYLLLFYACPRLGGAREGRSMAIWREEEDLRGNNLARLDETVHSDDDDAVVFQRNIFESYCKSVPRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U608</accession>
    <name>A0AAV4U608_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_29811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012326">
        <property type="protein sequence ID" value="GIY53157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U608"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12616" checksum="937A996106038474" modified="2024-11-27" version="1">MDTYSKKPTTSLKASTHNAKGDTRPNDFSRPVVFNPPGKPLHHARFFNLVQAELLPSGTNYSSHEFPAVCSCLWCVWEFDLCVTAMGPPEVLNNIAAHAGTVITHSHYYGNAAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UL10</accession>
    <name>A0AAV4UL10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_692921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013033">
        <property type="protein sequence ID" value="GIY58200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UL10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="19716" checksum="B49FBB9AC881B5DE" modified="2024-11-27" version="1">MSKKRTPENLGPVPTIAWCALGFYTVPFLEALCLSGNELEELPEGIVSLHRNLQKICLNPQLFQHAIYVPLNLLNQKIINSSNRKIDYRSDLHDIAHALVHLPKTKTNFPALFGSAKSPPTSSFLLTFPAATLFTKPWWPSICGKGVVNFSACQSSCSCDVQLAILTQQFRILHLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4USB5</accession>
    <name>A0AAV4USB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Titin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ttn_0</name>
        <name evidence="2" type="ORF">CEXT_646111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013379">
        <property type="protein sequence ID" value="GIY60806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4USB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633:SF7">
        <property type="entry name" value="TITIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18765" checksum="7557B3348F340571" modified="2024-11-27" version="1" fragment="single">ATKPEINPFHFGTLKIGERVSVTCVVRVGQPPFTFTWLKDGSTIQEMEVITIRNIDEFNSNLAITRLGPEHNGNYTCRVSNRKGSSEQSDVLTMMDQPPLIFIWLKDGSAIQEMEAITIRNIEEFNSNLAIIRLGPEHNDNSTCGVRNRRGSSEQSDVLTMIEKALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXS7</accession>
    <name>A0AAV4UXS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_175001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013643">
        <property type="protein sequence ID" value="GIY62622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9741" checksum="58EBE9143A6558A7" modified="2024-11-27" version="1">MNGWRVYGVFANYRTRLPQPAGLAMCARVRPSSVANVQNIANQPHAAAYRSAQSFAAQYTSRPPVSGPDNTCSHGWSGAWKASLFLLWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1L3</accession>
    <name>A0AAV4V1L3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_169471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013827">
        <property type="protein sequence ID" value="GIY64082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1L3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10895" checksum="60E5C2D9BDED6659" modified="2024-11-27" version="1">MSERLTAEQLSMLKADKNTNPITFYPRTGDEYLPHPTIYDLKEGNLKDAEFHSLKESGLLYVFSRRPSSTPLAEWMDTTHFDELHGICPWESTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5I5</accession>
    <name>A0AAV4V5I5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_731991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013997">
        <property type="protein sequence ID" value="GIY65500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5I5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="18637" checksum="91103633F4AAFF0D" modified="2024-11-27" version="1">MGIFVSIFDLPIPVVDKKTFKPCPFIQKPPLTAQDSRAANARISYLRSYEWNHVQHPRSDSIQGKRRFLRKTRNFVPPVWSSNYNRWDSIRSVPLDHLKTGANHIFQHQTSSPRRRITFIFHMRDGFINGQKSSRHTEEEYFPFLCFYLQNAEKNSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6F7</accession>
    <name>A0AAV4V6F7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014010">
        <property type="protein sequence ID" value="GIY65604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6F7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14256" checksum="BA0D1F218639F91B" modified="2024-11-27" version="1">MTEGCLEIHRPLLISNGKCQSSHGPGYRTLSEVQWMGRCGTRQHQFQMEGKGRIDPFILVRRAFVIIDVVHVNNENSGSTSLRISQIERRYVQTVLRYEFPVQGASTNNFPVCMSILKKLYSSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6Y9</accession>
    <name>A0AAV4V6Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_161271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014020">
        <property type="protein sequence ID" value="GIY65701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="20146" checksum="997AE3DACA3B2321" modified="2024-11-27" version="1">MANSKNEIGWQCLTVKWEPRATCFRNERVAIVENGSVVEGMEQKLFRAVELTLPRPGLKECSTGKNTLFPIAVVDSNSSQRGQAEIFHHYGEGHLSQELGKVDSVARLKGFCLPVHLWPWLALSIVYVSWSFTAEKRFWKLRSGFDLMLWIVFQIAIITKFHTNSLAMRKFCHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7N9</accession>
    <name>A0AAV4V7N9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_324941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014055">
        <property type="protein sequence ID" value="GIY65956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7N9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="14009" checksum="BDAF0685CE0E8E1D" modified="2024-11-27" version="1">MKNLRWFNKPSEISHSPSVVRQGEDGRRKMSALDKQKQRVTAPAKSQRNTAPAEEEVFDTDRKIRTTIKEQHPRRQRERSKEGNKNKKPRGSRYQARPSFLVSRHKPVCKKGRDMRQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V825</accession>
    <name>A0AAV4V825_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_348011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014090">
        <property type="protein sequence ID" value="GIY66188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V825"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10076" checksum="B5576658AD167CD1" modified="2024-11-27" version="1" fragment="single">AQREMQSETEDTVYYISDAETSPGDSFEFSEAECDMHLRLAMEEKTGLTFDPFLTGLFLRGVSAELKFPSAQLMIWNFFNKSPHYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAM7</accession>
    <name>A0AAV4VAM7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014230">
        <property type="protein sequence ID" value="GIY67342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="5779" checksum="C8CA9C74A72C6E57" modified="2024-11-27" version="1" fragment="single">GEAVLRGASIAAALSPAHLAVPNFRCVFITIPDLDIEKLTSKSHANALLLNFPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VB24</accession>
    <name>A0AAV4VB24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_285501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014219">
        <property type="protein sequence ID" value="GIY67253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VB24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8512" checksum="2B94BB93E75612A2" modified="2024-11-27" version="1">MLLRKQFLRQYLFPLQRERERVKAFRNGKLNMLFRKQFCTAVFIPSSDKVKAKLQKKNHPAPRSKKKHGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCL3</accession>
    <name>A0AAV4VCL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_9861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014273">
        <property type="protein sequence ID" value="GIY67700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17445" checksum="FB1DA92FFFA769AB" modified="2024-11-27" version="1">MKNCRQKTNVLSGVRDNPLGSGGMISCPKSIVGARWSVLEIFMRLRGSDHLGLTPVVLEMISSPKSIADKKRGKMEAVSFLEFYATRTKRPAVSITMTSQSLTLDDNANSQVQVKRHPKREMRKKRRGESWTLTSSRYPIHMMGPFLDKRMLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VH77</accession>
    <name>A0AAV4VH77_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_152121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014544">
        <property type="protein sequence ID" value="GIY69507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VH77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11203" checksum="2E30F6A0B45A05FD" modified="2024-11-27" version="1">MVFISYTIITEPIPVTAVICFVYFLQRAPYGNTHNQLLKNSAKPALQKLVPFKANVFQVCYARFQRNNFPHPGLGPQIAPLLMEGQRFSGQQERNQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNJ5</accession>
    <name>A0AAV4VNJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_289721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014844">
        <property type="protein sequence ID" value="GIY71708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043629793" evidence="1">
        <location>
            <begin position="22"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14858" checksum="A9645078DE5CD417" modified="2024-11-27" version="1">MSHLLYSPLAFLLVIRTGRLGQRFSLGRNQTASFQPDTTFWKRANDDLDPKVAPGLQKLSAFIRYRQWRALSRVYQTASGSQVLDPLDQIFGYLMTPGVQQNRFLATNGRDNAPEERSKHWSLKTYLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VP04</accession>
    <name>A0AAV4VP04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_138541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014867">
        <property type="protein sequence ID" value="GIY71873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VP04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9960" checksum="28D620CDE3925EFB" modified="2024-11-27" version="1">MKTSDCKNSKNSAIFPNEHGPTYDVTHTTYTFPLHRRRRYKNKSRGFINNSILLSALNSAGRCLCSVAIRRNTIFFPRHRLRFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWP0</accession>
    <name>A0AAV4VWP0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Vacuolar protein sorting-associated protein 51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">vps51</name>
        <name evidence="8" type="ORF">CEXT_94201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Golgi-associated retrograde protein (GARP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
            <location evidence="4">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the VPS51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015153">
        <property type="protein sequence ID" value="GIY74014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990745">
        <property type="term" value="C:EARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007041">
        <property type="term" value="P:lysosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014812">
        <property type="entry name" value="Vps51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="7">
        <location>
            <begin position="23"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="613"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="613"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY74014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="723" mass="84299" checksum="8AAAC3FDE9A3F067" modified="2024-11-27" version="1">MSGVEDEQRNRRRGLLKQYYGFTEDNKEGFDPYNINAPEFNPDLFLHKLLKECNLNQLMQKEHQIYRQIQSLDSEMQTLVYENYNKFISATDTIRKMKNDFKKMEEEMDCLSSNMSIITEFSGNISSTLQGRRQQISKLSGVHALLKKGEFLFELPPGLKMCIENGSYRQAVRYYLKAQKVLHQYEHMPSFHGIQKDCDILVNQLKMKLREQFKSKDATPKQLAECVDLLLQLEEPTEVLCDEFLKHAKEKLDDDLHELESHLNDTEKSPTHKSDSTPDETDKKLMDILEFIDFSYNNFVSNTSLVIASYWDLFLQKPTAADDSEQFSKEKRNWKNYWWNSSSDDAILVRALDRFYRRVQAMNRLLRHIDFTLRGIQIVKKTAQERCNYYLQKLIECFSAAMVNMRQSIAAPRTLNQEGSKGLTDLLNVFESQISSRINTVQADLQLFIQTDITFAMKIQFKEEFCREYVREGVIIAFLRHINKTCQEFCSYNERNTVPAQLILVLSRFCLNLEQSSISEWVSLVDDSFSILNDNGLTSISDICMETKEVAQNLIDHFVKIQGLNISQMLRKSVETRDWLNAIEPRNVRAVMKRVVEDVTSVDAEVGQLYEEGVRHERSSDSSRRTYPSTGRSHRSKYNAYAPSTIDNSLMSNIQKLFSEKIEIFSTVEFSKVSVMTGIIKISLKTFLECVRLRTFSKFGLQQVQVDIHYLQLYLWHFVADEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZ39</accession>
    <name>A0AAV4VZ39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_12680_1</name>
        <name evidence="2" type="ORF">CEXT_343141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015378">
        <property type="protein sequence ID" value="GIY75712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZ39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="15997" checksum="A60C467D49A3D4B6" modified="2024-11-27" version="1">MTIFEQNESGVTDVQTVKPVTNWIISPTLSPTGISHHQSYLYVSTIVLAIVIIGTAILVILRACYRACIISNCTIYPSPAEVPIITGFRPTMVPTDAILINGRFLPDDDKPPSYSSVAQVYEINETSETQLLIKSETPPPSYQSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZX3</accession>
    <name>A0AAV4VZX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_494081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015304">
        <property type="protein sequence ID" value="GIY75154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13683" checksum="60FC4CE969059E96" modified="2024-11-27" version="1">MVIQEWSRFLWSSRNGQPFLWSSKNCQDTNSDPGIVKILIVIQELSRYKWSSRNDQDSYGDQDSYGHQGMINHCYGHQGMINHSYGHPGMIRFLLSSKNGQDSYGHQEMVNILMVIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBX8</accession>
    <name>A0AAV4WBX8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_421271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016002">
        <property type="protein sequence ID" value="GIY80346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="15274" checksum="09937DCA73C33B15" modified="2024-11-27" version="1">MIHHPSKISSKFLDDFPEGYVCIQRRLSGKQDLQLYGTREIKKNSPLLPWNRSETRTAPKMTTYAIFLTFLANYVLQRCSTLVKAMSKRSHLTASEAWKVIGNLERGQTQSVVKESRSNITKYNFKGSEIESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WG24</accession>
    <name>A0AAV4WG24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF5641 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_190690_1</name>
        <name evidence="3" type="ORF">CEXT_453421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016062">
        <property type="protein sequence ID" value="GIY80926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WG24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040676">
        <property type="entry name" value="DUF5641"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18701">
        <property type="entry name" value="DUF5641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5641" evidence="2">
        <location>
            <begin position="86"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY80926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="23774" checksum="1B2D28F1E41C01F1" modified="2024-11-27" version="1">MIRTVKQLLRKVLGRACVSYEEMVTVLCECERIVNGRPLTYIYDNPNELRAIKPSDFIRHKGNETMNLDIVDAKHLRKRIRYLQNLRYQLRDIVLVGSDNTKRLNWPLGRIIELFKGKDNVERVARLRVAKGEIIRPIQSIYTLELSSSEILNDVTVRVKDSSDTSDNDNQHTVSNEQSFEPKDLPKEQLETLKDHDLVDKLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHK2</accession>
    <name>A0AAV4WHK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear pore membrane glycoprotein 210</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NUP210</name>
        <name evidence="7" type="ORF">CEXT_744781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016137">
        <property type="protein sequence ID" value="GIY81530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058779">
        <property type="entry name" value="Ig_NUP210_13th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057586">
        <property type="entry name" value="Ig_NUP210_16th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045197">
        <property type="entry name" value="NUP210-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055094">
        <property type="entry name" value="NUP210_Ig15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055095">
        <property type="entry name" value="NUP210_Ig_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23019:SF0">
        <property type="entry name" value="NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23019">
        <property type="entry name" value="NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26181">
        <property type="entry name" value="Ig_NUP210_13th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26183">
        <property type="entry name" value="Ig_NUP210_14th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22959">
        <property type="entry name" value="Ig_NUP210_15th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25354">
        <property type="entry name" value="Ig_NUP210_16th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22957">
        <property type="entry name" value="NUP210_Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="Invasin/intimin cell-adhesion fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="42"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="NUP210 Ig-like" evidence="6">
        <location>
            <begin position="129"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="NUP210 Ig-like" evidence="4">
        <location>
            <begin position="340"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="NUP210 Ig-like" evidence="5">
        <location>
            <begin position="442"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="NUP210 C-terminal Ig-like" evidence="3">
        <location>
            <begin position="528"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY81530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="852" mass="93025" checksum="4EFC346C1D536DD7" modified="2024-11-27" version="1">MLHMYKTFKGLSLGHTNFKIVTKANIFKGVQYSSDTCPIQVFPPLDLNPDHVVLVVGATFQVLCSGGPQPLSNIEYVMDNKDIAVVSACGTVEAKKVGSTTLIARSVGLDKKGNTVVFSEDKTLVSCVSLKEVKIHAPLSRMIAGTEMPLYAMGHTDSESPFTFGTAVPSAKFKWSISNDKVASINTLYSPVGLQETSANNFRVVLKALQDGLVTIRLEVTLPKETSISFLGGSQVLSAEIQIQVFKRLRLTNPEVEDGMIIMSPNSQLKLKCNRIGVAKVSYKVLPSVAKMNQLPVVSIDDAGQLIASSRLGTAILQVTAIEESGITQDLSAIVKVEETAYLMLKPVGKIRTRDWPLTVLPVGYSAPFVVTYHNNIGQVFDAVRSHLQYRASRPNSARVSFGSLNNTLSIQVVNPGFTVLKVWDVEASIPPDYIQIATGTAIDPADIELTVGDVICFGSPLVTQEGHSGTWSSSKAILAIHPVSGGAVALNSGQTVVVYSLLNGFSTSTQVTIKDAASISIEPGNVNQISNYPRTKPYKIFIVVQSNETHRTNNIVGKNCTHATESSMPLPLVQAPFSCELNFLSSSADITANELFHASSGMYYCSIEPIRKLPISEISGLEGQLSLTAHLLSTGPSSSLSQQLLLSFLPAFHVQQDELVLSDIQNTNHVIVSATPAVQRCLLVVPSDPTVLRGDLSPLYIEINCPVTKQQVKLPIKVKRLEVQLDGNTYCQPLPLPPSNEIVFDWYLMAKVAAAMMSILLVYYFFRWVTSVRRGMVTSQPVFLNQSSSFNHSSNGSLSLSPVHRQFQSTPFRQRFSPTPDYENLSQPLRHCHLETSPKTLQRRRTDNIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WKQ3</accession>
    <name>A0AAV4WKQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_231391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016190">
        <property type="protein sequence ID" value="GIY81990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WKQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9591" checksum="501B9113345768F7" modified="2024-11-27" version="1">MGRYKSWPRQNPILFPGSLSSAAVIECEIVHWAGRGQKGRKLPKNDTYLNSSLIGVHPLCGRSVGSEKQFSSRRPRKGLQTASLLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WNU1</accession>
    <name>A0AAV4WNU1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Atg13</name>
        <name evidence="6" type="ORF">CEXT_400901</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATG13 family. Metazoan subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016475">
        <property type="protein sequence ID" value="GIY84146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WNU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040182">
        <property type="entry name" value="ATG13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018731">
        <property type="entry name" value="Atg13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13430:SF4">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10033">
        <property type="entry name" value="ATG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy-related protein 13 N-terminal" evidence="5">
        <location>
            <begin position="63"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY84146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="395" mass="44588" checksum="23E09D853D708773" modified="2024-11-27" version="1">MSQVIVQSRFGDKHSCSLKKKSIHEWFNLAIEDNVEIQAKAKEACSKVHLLKDFCICTEILLKTSDGDTLVLETWCLSMNTSDCISDTPYVAYTSLANVYCRMTLLLKSIISVSRITPAFKLSTCQSAETYVILFRIYPGEPQVQELGKNYVTNKIGQILTPVGNLKVSIYYRSKDNLMITPQKIEKGNSFMLKSDYFKPDMNSKISNSDDSKPEDDSSCPNIFGDFHKKGAFALPNNCQDALFPELDMLEKPFLNLSRSRLSRIIKLKEEDSTTNADKNANMNHIDNKEKSSTVDFNCNANEECCRKLTFNELLSSNDFLMMEMKPPFADCDGENDIGAFFRECQSAPPLASFSAQPTLEEQVTDITTQLVKFETSMIDFDSFVDSICHLDVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZQ2</accession>
    <name>A0AAV4WZQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_701661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016983">
        <property type="protein sequence ID" value="GIY87838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12262" checksum="8EBE83F2603B68ED" modified="2024-11-27" version="1">MLPVTRWPDTGRISRSRIYLGASDVSSCCPRTSGVSSLGASGVILWEEVNGLRVPWSAFGIQMFPLSSAQNTNHVLWFDKILAGVVYVWILVFVIEQFLCLERRSVLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X073</accession>
    <name>A0AAV4X073_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Speckle targeted PIP5K1A-regulated poly(A) polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tut1_1</name>
        <name evidence="2" type="ORF">CEXT_380131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016897">
        <property type="protein sequence ID" value="GIY87168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X073"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF127">
        <property type="entry name" value="SPECKLE TARGETED PIP5K1A-REGULATED POLY(A) POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="1">
        <location>
            <begin position="82"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="431" mass="49336" checksum="50E441F983AFA800" modified="2024-11-27" version="1">MNQNVLTAKILIKKWIKSHSCKKIFCFLNLENNVHTVRHICFYATARNHYIYTPKTKSTENTEKFLSHTHLKQLLHNCKSVKEQIEVFDSYTKLTDEDVAKRQSLCQNIEKIFRQHIPECSVHLTGSTASGLGLRGCDVDLTFQHSSNEDDQNNSIAKVVSSDFVRDIKMGKIPACDFTSLKSNMKLHILKNALRNSGLIKESTVVPGHCPILNFTLENLSWDLSVNSLSASQGTNLMLLCRLLDSRLGSLHRLLTYWVKHLKMSGGPLKFKSYAIFLLLVHFLQTRSPHILPSVEHMLDKAEFKNNLDNWSYDISKYVDKFERSENSQSIDELIKEFFFFYAKFDFSDVICPLTNCSEKARDFISKYDSPENKFQVTEISVQDPLYPSKNVTYGVSWKLCNLRGLDCAHLQRHPALSASSLWVLGVEKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4R5</accession>
    <name>A0AAV4X4R5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_186831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017304">
        <property type="protein sequence ID" value="GIY90220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4R5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043585121" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY90220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8472" checksum="8B5338DBB05B81CB" modified="2024-11-27" version="1">MNCLCLFNRNCVLLAVSLAFLEGDAPPKQHTSSPCSDRGNKRGGPFQFPTMELQPLVTPRSMRYSEISSPNENRAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBV8</accession>
    <name>A0AAV4XBV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_156591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017498">
        <property type="protein sequence ID" value="GIY92102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13064" checksum="6022AD6E3DD7C1D7" modified="2024-11-27" version="1">MVVRRIHLPSVRLGYHPEQEHPSLGGDKTASPSHATDVHGPTGRTNSDHMPVTGRHPWQLRLQLGQEQPHPQPILGAGDGGRPVSLQAVDCSYIPQGPLQHTPVLSPVQLDPRGRIVLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFY6</accession>
    <name>A0AAV4XFY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_388051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017594">
        <property type="protein sequence ID" value="GIY92866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15408" checksum="5547C6C674D382E7" modified="2024-11-27" version="1">MTVMMEVRSDCPFSGPFEEPNLYHIHSNFPEAQQLMTLISSTTIMSTKMLGNFGPRIQNLSFQGPYYIFTIVSRPILHIYNSFKAHITYFTIVSRPTHILEGCKPIPKHVKLKDKFREQYQNHAYTAKLSWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGV9</accession>
    <name>A0AAV4XGV9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Nurf-38</name>
        <name evidence="11" type="ORF">CEXT_3621</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01000323">
        <property type="protein sequence ID" value="GIY93887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY93887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="277" mass="31602" checksum="0AA27D186EFC5D6C" modified="2024-11-27" version="1">MLIWLPNFYADENGPISPFHDIPLFADKENKIYNMIVEVPRWTNAKMEIATKEALNPIKQDTKKGALRYVHNCFPHHGYIWNYGALPQTWEDPNHTDESTGCKGDNDPIDVCEIGFRVAKRGDVLQVKILGVMALIDEGETDWKLIAIDINDPLAEELNDIEDVEKHMPGFLRATHEWFKIYKMPAGNPENKFAFNGEAKNKEFAEKIIGETHNYWLKLIKNETDANGLDCSTVTITDCPNKIDVINALTIVQKSEEPGSSQDVDPIVDKWHFIHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHW4</accession>
    <name>A0AAV4XHW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_66231_1</name>
        <name evidence="2" type="ORF">CEXT_109931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017652">
        <property type="protein sequence ID" value="GIY93363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="19813" checksum="1430828F37123C69" modified="2024-11-27" version="1">MRTHSPETLSYAIEVECILVLLATGEKTALGKDLQHAYLTWQKLSPSFRRELNTRMQPCFKSTGQKELYECLIRGFDIWDYTQNLDGAPGWSINESSINQVLKHMGEDLMNLLHLMDETCVNHKKSSPVTSLAKFDGCSSVSPCDEGTGDQAISFRPRREEHSSMRRSSKEGNGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ12</accession>
    <name>A0AAV4XJ12_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_392912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="BPLR01000365">
        <property type="protein sequence ID" value="GIY94205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF7">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY94205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="331" mass="37904" checksum="434009CEC59A10B8" modified="2024-11-27" version="1">MLRSNICSRLHERSFNSPTIRLLYVSRCFGSSGDFITSPEVSQVFGELIGIWFYNEWCKIGFPQPLQLVEFGPGRGTLTDDILRVFSKLTSQHKSNLNLSVHFIEVSPHLCHIQMSKLCSRHVKEELHGKTLTTKYGFPITWHPHLVNVPEAFSLFLAHEFFDAMPIHKFQKTSDGWREILIDCKDGELQFILSRNPTAATKFLIDKNEQRDHVEISPTSGILLEEITKRMKEDGGITLIADYGHLGTKTDTFLEVFKKHQLHNPLKNVGEADLTADVDFQFLSKHAKEKAVVVGPVNQASFLKNMGIEIRIQELMQRATKRESRIFKNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ52</accession>
    <name>A0AAV4XJ52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_169711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000413">
        <property type="protein sequence ID" value="GIY94674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17217" checksum="C6D9DAEC473202B4" modified="2024-11-27" version="1">MIATNVVSQNMLDAPYSNDDQTELKTGKPPRNRDSNWNRTGMADCSFCLLNPVITGSRALFVFGVRSLMNLFTKHTHTYTRTLKGSIIFQQVHRQPPYTCHSEYLRKRANCVLNAFKELGEGMVWVVSPPQRTLISDLAVSLNGGVWEQRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN78</accession>
    <name>A0AAV4XN78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_307881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017923">
        <property type="protein sequence ID" value="GIY95519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="10040" checksum="89525CA89EFB4401" modified="2024-11-27" version="1">MLRNPKSLSYASDKVTKPSRANVLSILWSRKFNTRNRLCRGKVINRREVNDLSRDHHTRFTSIVSKNIEFTIGHEYRISPLARER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTM7</accession>
    <name>A0AAV4XTM7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">POU-specific atypical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_223782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000930">
        <property type="protein sequence ID" value="GIY98511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTM7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040363">
        <property type="entry name" value="HMBOX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044869">
        <property type="entry name" value="HNF-1_POU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14618:SF0">
        <property type="entry name" value="HOMEOBOX-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14618">
        <property type="entry name" value="HOMEODOX-CONTAINING PROTEIN 1 HMBOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51936">
        <property type="entry name" value="POU_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POU-specific atypical" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY98511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="222" mass="24712" checksum="16C2A45CFC9B8D39" modified="2024-11-27" version="1">MSDRTKNAFYMWYLTCKNNPWKLTQLCPNSGVKRMVSEKARSHPSEKRALHIQSSPPSIDECNKAVERAVRVSDRPLAERERVTLPVVNNWFNNRRKEAKKQLRQQHAAAMAAVSVGMSSLSQQSLGLPSVASMPSLNWHQSVEACPALWEGVNLHPSTPMLSLISAARPWIVTAPGILMAMETLFPSRTTTSPLTSSKRCDNLSCSPWEVEKIGILDLSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWU4</accession>
    <name>A0AAV4XWU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chloride channel protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ClC-a</name>
        <name evidence="11" type="ORF">CEXT_223454</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000930">
        <property type="protein sequence ID" value="GIY98459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03683">
        <property type="entry name" value="ClC_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000032">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3080.10:FF:000033">
        <property type="entry name" value="Chloride channel, voltage-sensitive 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050970">
        <property type="entry name" value="Cl_channel_volt-gated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45720">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45720:SF10">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0868">Chloride</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="514"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY98459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="766" mass="85042" checksum="DCFDE95E211E0CA4" modified="2024-11-27" version="1">MDYAISMCQKSRIWLYRDLTAHPFLQYLAWVALPMCLILFQLDLNICHCVPLISKVIGLTCTLGSGMPLGKEGPFVHISSILATILSKLVTSFKGIHENESRANEMLAAACAVGVACSFAAPIGGVLFSIEVTSVYFAVRNYWRGFFAACCGAMVWRLLGVWFKNEETLTAIFRTNFHIDFPFDPQELIVFAGIGAVCGLGGAFFVWFHRQIVHFNRKHKRMNAFLQQNRFIYPAVITLIISTMTFPLGLGQFMAAELTTHESMNELFSNVTWSNRHLEVDEAIIVSHWTTKYTNIFVNLVVFIIITFLTTTLAATLPVPSGLFIPVFKMGAAFGRLVGECMASWFPDGITLGGSVNRIIPGGYAVVGAAALSGSVTHTISTSVIVFELTGQMSHILPVILAVLIANGISQALQPSIYDSIIQIKKLPYLPPIVSTSSEAHNVYVADIMVRDVVSVWRGCSYKDLRSILKLKKRLQFFPLVESLESMILLGSIQRIELLRLLELQLGRERRLQEAAKRTQLSESPKTPRTEKKPSRFEVVPVVSSTRNAPRPGQESIGNTPSPKCSPPPSPVATPKSPKKSFLRYSPVNSPYNTITSLDARLKQAFENVFKKALTDPFEKFESSVPSTPVTKRSQQPRILVDMSPEELLAWEEDQLNALVDFGKCHVDPAPFQLVERTTLIKVHSLFSMLGLNYAYVTAIGRLVGVVALKELRKAIENISSGLFITNTNHFGHGEKSEPRLKHNPSARTIMVLLCNNWPSINLCNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWU5</accession>
    <name>A0AAV4XWU5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_233561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018399">
        <property type="protein sequence ID" value="GIY99219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWU5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="39" mass="4541" checksum="F0C0F88E781E9639" modified="2024-11-27" version="1" fragment="single">LTTSCRFARAYRSRTNLITKGFTAGRWLMWSDSDRRSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX16</accession>
    <name>A0AAV4XX16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_288961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001028">
        <property type="protein sequence ID" value="GIY99287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10180" checksum="70B92B543A2B4BC1" modified="2024-11-27" version="1">MLETPADLCKSPLRFRFLRNVVLSVPSKFNQSSTDRSESAETSCRVRTLPHWSKERWTKGFEGSSRRALTLKSLNEYLRCRNSTLKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ65</accession>
    <name>A0AAV4XZ65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_305831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001112">
        <property type="protein sequence ID" value="GIZ00060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14127" checksum="55F35B6152AE3B02" modified="2024-11-27" version="1">MYGRIGNLIFNSSIMFTKFNLLNCLSKPEVCGNRRSSHLNSLTVGLGKRARCSPDHLCIWPPWTPSPPLIDNPAWVCRWRHFNSPPSCAANLLSFQLTSGKFPHNMSIQPPRSRLHLTTNLHGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3E5</accession>
    <name>A0AAV4Y3E5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_216411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018604">
        <property type="protein sequence ID" value="GIZ00950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3E5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12577" checksum="792892B1A472E0BA" modified="2024-11-27" version="1">MHQHCSKRFPLMKTSPCKGKAAALQSILSPGPLQFTRLNVEQPLSRGQLKLEWQQMHQHCSKRFPLMKTSPCEGKAAALQSILSPGPLQFTRLNVEQPLSRGRSVRKTEHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y631</accession>
    <name>A0AAV4Y631_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 4V2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Cyp4v2</name>
        <name evidence="11" type="ORF">CEXT_680011</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001365">
        <property type="protein sequence ID" value="GIZ01910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y631"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIZ01910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="244" mass="28264" checksum="BEC6F261380BB954" modified="2024-11-27" version="1">MLDKIRCPVFLIFPKHYYSDTDTSNRGSVTRKWVFFHVSVLQSIAGYYQLFPKSPLVCFWMSYMPIIILRTAEAVEAFISGTKNMEKSSEYNMVHPWLGTGLLTSHGSKWKSRRKLLTPSFHFEILKDFLPVFNEQSQILVKHLQSEITKDFTDIATPITLCSLDIICETTLGVSIGAQKNSESQYVKSVSRASDLIFVQIALNWHNINYLMKLTEGGRELSYHLKILHEFTRSIIQKKRKRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBL5</accession>
    <name>A0AAV4YBL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_575391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019116">
        <property type="protein sequence ID" value="GIZ04632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11606" checksum="A7A1664C877278C5" modified="2024-11-27" version="1">MHYSRLDAFLPQAYTLEMDVEVVFAKVSLEMSSSKTDNDINDLAKRKKQDISSYYTLVPKSHSKQSSFKTLTQTNPCSPMKFGIRAFPPQQSSRRPSLLCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD29</accession>
    <name>A0AAV4YD29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_456081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019232">
        <property type="protein sequence ID" value="GIZ05188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8433" checksum="570FF014371B261B" modified="2024-11-27" version="1">MRLSPLHFTSGCRHEFSTSRSRAAKKLSKEEEEEKRKRRKKKKKKKQKKGSHLGSFAILFIAAVKSCLEMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YG42</accession>
    <name>A0AAV4YG42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ankyrin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Ank3_6</name>
        <name evidence="13" type="ORF">CEXT_366601</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019224">
        <property type="protein sequence ID" value="GIZ05152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YG42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24134:SF9">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24134">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="11" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIZ05152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18213" checksum="33082F113547E815" modified="2024-11-27" version="1">MLENEIKKGEKHSSYCFANAKCVKNETLLHFASKKGCEEIVDILLKHVINPNARDPNKYIPLHCAAKSSHFNVVKSLLMNGSVYNALSHNQETPLDIAVGKEVINLLRFVSESFKKVQLNNHSVLSDLRKDINLAKAALRAKNRACKNLVEVSVLCGFPKQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M632</accession>
    <name>A0AAV4M632_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Gyc76C_11</name>
        <name evidence="7" type="ORF">CEXT_50811</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP = 3',5'-cyclic GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13665"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57746"/>
            <dbReference type="EC" id="4.6.1.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01001912">
        <property type="protein sequence ID" value="GIX67927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M632"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX67927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7784" checksum="3EE54CB10B9E031E" modified="2024-11-27" version="1">MTYLHESQLRSHGNLKSTNCLVDSRWVVKIADFGLHELKFGSDSGDDDSTDFEKQCARICKLFRSECN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAG9</accession>
    <name>A0AAV4MAG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lon protease homolog, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Lon</name>
        <name evidence="3" type="ORF">CEXT_55901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002045">
        <property type="protein sequence ID" value="GIX69369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="1">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Lon protease AAA+ ATPase lid" evidence="2">
        <location>
            <begin position="129"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX69369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20512" checksum="5D92D1195558D626" modified="2024-11-27" version="1">MTDVAEIKGHRRTYIGAMPGKIIQCLKKTKTENPLILIDEVDKIGRGYQGDPSSALLKVLDLKNHNFLDHYLDVKDLSKVLFICTANVIDTIPEPLRDRMEIIAVSGYVAEEKIAIAEQYLIPQARVSTGVKEDQVTLNTDALQKLIKSYCRESGVRNLQKHIEKILRKAAFKIVKKKFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MH52</accession>
    <name>A0AAV4MH52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_611251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002249">
        <property type="protein sequence ID" value="GIX71731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MH52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15320" checksum="2CF099B55D56C46D" modified="2024-11-27" version="1">MSIIAVPPVVLSEDEFNYCPFNFERHDDPSSYAHDHLKSKSTALIHLKHLEDLQISLVGIKMHILSQLKIKIGMVTLLCSSLLAIPCTIVLRAWIGMFGKEKMTELVMEETIRIPNSIRLFRYGNDDASYEKDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPW6</accession>
    <name>A0AAV4MPW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein mesh</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_572401</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020070">
        <property type="protein sequence ID" value="GIX74476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056619">
        <property type="entry name" value="C8-3_MUC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051495">
        <property type="entry name" value="Epithelial_Barrier/Signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13802">
        <property type="entry name" value="MUCIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13802:SF52">
        <property type="entry name" value="MUCIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23263">
        <property type="entry name" value="C8-3_MUC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0768">Sushi</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="VWFD" evidence="9">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="8">
        <location>
            <begin position="236"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX74476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="366" mass="42237" checksum="A0D0FBA86A2BA8D3" modified="2024-11-27" version="1">MAVAARDNASSIVEFRVRPAPARWQYHMYIIVDNEYVYFWDNSLRVQFFKGVTLFQPANVYNMSHIVAMFDSGAGVEVMVENGHMAAHVYLPLTFINKTRGLLGNWSRIKEDDFTAPDGEVYITPDSRTYDVHHRFGMQYRVSEIGNNKVGRSLFFHNAIPFSQYDNMSFVPEYETPPPIPKNFNYRPEEIENTCTTSMACRFDFLVTGDRDFAWATRNHENYAQKLAADVRKSTIRCPELVKPRHGRKSEIRYYVGTTVRFACDDGYRLVGYENRRCRETGLWSWGVDPQCISNGDYIRKIVGISLGIVLPVIILGVLFCICMIQRLRYRKQHWTGERGVITNAMFEMKPNRNGAENGSSKVSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR42</accession>
    <name>A0AAV4MR42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_570821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020101">
        <property type="protein sequence ID" value="GIX74822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9807" checksum="959436EBB38DF27E" modified="2024-11-27" version="1">MDEKEKNYKYFLEVTTIHSYTRGVTLYQVTNGPFLTLQMGFREDPFIILGISFSPGESKSNISEPLPSHQLYIVCDLQACFEESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTZ3</accession>
    <name>A0AAV4MTZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_612111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002584">
        <property type="protein sequence ID" value="GIX75405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11632" checksum="D331F071A1B61621" modified="2024-11-27" version="1">MPTKTVHWEILLIPPCFLKLPGKFPTQILSQRLQLLILNQIAASPNIQQRNYSKLPAVACSQTLEFPDSALLLWCRRKGWQQFLHHAVGSIEYPWLARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N168</accession>
    <name>A0AAV4N168_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">FMRFamide-activated amiloride-sensitive sodium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FANA_1</name>
        <name evidence="13" type="ORF">CEXT_633201</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020296">
        <property type="protein sequence ID" value="GIX77039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N168"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX77039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="24750" checksum="63BA7AB2D7A6CAE6" modified="2024-11-27" version="1">MRIDIHDQQDPPLPGENGITILPGYQTDISLSEIITSRLPKPFEDECISYNSMQSQSMCLGVCLQNYNYAKCGCVEPLFPEIEHRKLCNITKVSDVCCLDSVLVDLTQGADCNCPLPCLSTHFSKQISMAVWPSQKSFFKGNQNASFEDLKLYRASHAKVRIYYKTFERKIFDQKPMFHPSELFSYLGGECALWLGLSLTAFFELVELLLPRKYHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9K4</accession>
    <name>A0AAV4N9K4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Metabotropic glutamate receptor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Grm3</name>
        <name evidence="11" type="ORF">CEXT_713631</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020645">
        <property type="protein sequence ID" value="GIX81015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9K4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017979">
        <property type="entry name" value="GPCR_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00981">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX81015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="256" mass="28658" checksum="02491E262DBAC16D" modified="2024-11-27" version="1">MASGRELCYVILVGIVLCYCFPFIVLLRPTDISCGALRIGMGLGLSVCYSAIFTKTNRLSRIFEVSLKFTKRPSYISPESQVMICVCLVLIQITLTALWIIIKPPIVLQKLVPSPRMWVIYCGVDGISVLLGLLYNMVLLILCTVYAYKTRNIPENFNETKWISFTMYSSCIIWLAFIPIFCSAMQDYKVQTTILSMSVSASGTVTLVCIFLPKIYIVLFHPERNVRYPSSTATTGTGTCDSSQAVRYLRTVPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCV4</accession>
    <name>A0AAV4NCV4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_427791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003150">
        <property type="protein sequence ID" value="GIX81650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCV4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11285" checksum="FA32BEA720FB58EE" modified="2024-11-27" version="1">MTVRIDEHKIAKRKIWMQSLHKNNGQTEDTKRTLNASSPFSLSWEYFNKRPATRGMEFKDLLFSDPKQFEKGFLPRFLLPFVASYTGSVNSWKARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEL9</accession>
    <name>A0AAV4NEL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_370051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003270">
        <property type="protein sequence ID" value="GIX82804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10606" checksum="5876AB7C6682E47A" modified="2024-11-27" version="1">MISSASASSGRNHEIQTEVLLWRARVYSSIRVITPPQPFAAGFLLESWHPRKSCSRLGIVGRGSCPSQSTFWRKKIRTREEPDLEGPSERRALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NES8</accession>
    <name>A0AAV4NES8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_646951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003322">
        <property type="protein sequence ID" value="GIX83317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NES8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10899" checksum="B6D2AC945B13F75F" modified="2024-11-27" version="1">MIITFKFWSTRQQFMSCQIIKLAALPASFPAAVFEAKSFKITESSLRNSKATFDTHASREFGIPVRRVLRKYFRAGIPSRSKKEWREPPESIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NI57</accession>
    <name>A0AAV4NI57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_216931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020874">
        <property type="protein sequence ID" value="GIX83538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NI57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11571" checksum="2D78650F2910109A" modified="2024-11-27" version="1">MKINRHPDLHRLKVPVTSPQQQQKKNCNISYKYSQNKLLEQKNSFSGRDLSRTRGRFSIVSVFTRLTKERRAFGNNKCKSTEKKSGTSSSSPPPFFFFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMB8</accession>
    <name>A0AAV4NMB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kinesin-like protein KIF17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KIF17</name>
        <name evidence="11" type="ORF">CEXT_768351</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003558">
        <property type="protein sequence ID" value="GIX85944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF21">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX85944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="22911" checksum="DA759757CFCF8F97" modified="2024-11-27" version="1">MGLFLYGQTGCGKSFTMQGIPHPASQKGIIPRAFEHIFEAISTTENTKFLVHASYLEIYNEEIRDLLGKEVKKKLELKEHPDKGVYVAGEITVFGFKTEMAFFASCSQYWECEEVMETGWKNRSVGATLMNADSSRSHSIFTIHLEMLEMENCGEHIKQGKLNLVDLAGSERQAKTGATGDRLKEATKNQPVIVSFRKCNFCIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NN38</accession>
    <name>A0AAV4NN38_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G_PROTEIN_RECEP_F1_2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_62259_1</name>
        <name evidence="2" type="ORF">CEXT_106731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021118">
        <property type="protein sequence ID" value="GIX86197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NN38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="261" mass="29573" checksum="F23C24D826C5E7C6" modified="2024-11-27" version="1">MLKGFFFLYVTLYGEWTDTLKHINQNLFTLAGCFYYFNSTINPILYSVMSNRFRVAFREKLCAGPPSLWCICCCCFCCVKDFEKRSQQTPVFCRNSNSHSSVRSCVSYHKTNLITNNNRPRTLAVDYNQKLGVTMSCVHRDQVWTPTSSVRKYGPTLTVSPPISSQQHESSHSHRSSSSDTHRRNCQGGQFLQQRRGGRLEGGGRGELRRGAGRGTETRTGEAGGEGECQRLHQLHQLQLAVPSKTEGGCWWNPRESDLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNB2</accession>
    <name>A0AAV4NNB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Extracellular matrix protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ECM3</name>
        <name evidence="5" type="ORF">CEXT_698291</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003575">
        <property type="protein sequence ID" value="GIX86274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039005">
        <property type="entry name" value="CSPG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051561">
        <property type="entry name" value="FRAS1_ECM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45739:SF8">
        <property type="entry name" value="FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45739">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16184">
        <property type="entry name" value="Cadherin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51854">
        <property type="entry name" value="CSPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="repeat" description="CSPG" evidence="4">
        <location>
            <begin position="25"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX86274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16746" checksum="ACFB48C4FD2837C5" modified="2024-11-27" version="1">MFEIRLEISYQTKNLQFCCNQWTTNHQSYITKGIDILENGFVVITPDILDVTDEDTDPGLLTFSVTEKPKHGTLQIGTLQMSNGDSFTKLDINSGIVSYSNGGSEADSDSFNLYVTDGVHIVPVTVHVSIKNIDDEAPKLEIAHGILSVILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPX7</accession>
    <name>A0AAV4NPX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_164661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003492">
        <property type="protein sequence ID" value="GIX85242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="13" mass="1426" checksum="DCCEF09C9402569D" modified="2024-11-27" version="1" fragment="single">MLKPVAMYLSGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCV3</accession>
    <name>A0AAV4PCV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_641791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004371">
        <property type="protein sequence ID" value="GIX94410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8524" checksum="351F22961B6718AA" modified="2024-11-27" version="1">MTSDSKQDDSLELYTFFFVCRTCKEDRGRYVIWYDYYAVTSYDYCVICEYCEEKFKVGYGVKTKLIDEPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PF22</accession>
    <name>A0AAV4PF22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_495221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004554">
        <property type="protein sequence ID" value="GIX95716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PF22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8219" checksum="D52B0A932C20AD82" modified="2024-11-27" version="1">MQVINSVFPPYHPAIGGGKPPTDLRGLLLIDSGKPVSKMFQPFTRESFDKDRVEVRSFGMVKSQTGHHVPVLGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PHH3</accession>
    <name>A0AAV4PHH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Importin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">IPO5</name>
        <name evidence="9" type="ORF">CEXT_806941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004390">
        <property type="protein sequence ID" value="GIX94542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PHH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041653">
        <property type="entry name" value="Importin_rep_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041389">
        <property type="entry name" value="Importin_rep_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18808">
        <property type="entry name" value="Importin_rep_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18829">
        <property type="entry name" value="Importin_rep_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TOG" evidence="8">
        <location>
            <begin position="360"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX94542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1058" mass="118787" checksum="B575037829EC2E80" modified="2024-11-27" version="1">MADNPASKNFRFILTNLLSTDNDVRAKAELLYDEVQATDKFFFLLSILGDNSVQLEIAELSAVLLRRLISAEFEQTFSKLEPNVQNEFKNQLLLRLQEDKNCNLRRKICDAVAELARNCIDDDGNNHWPDFLKYLFDSSSSPDPFIRELALLMFSAVPGVFGNQQSRYIEVIREMLSRSLTDQQSQQVCYVAVKALSNFLLANEKEGHVLKQFTDCLTLLTSGNSSILIQVLDSKEGQPEEILRYLVDLVEACPQIFRGQFDVLLELCLKGISNPDQEETGHLCLEVIVTLCEAAPAMVKKLGAKHIPTILTLSLKMMTDIEDDPKWDFLDDDNSDDDHDRCINILHSVVAEAALDRLACALGGKTVLPFVLNMLPQMLQSSEWKERCAGLMAISAIGEGCHKQMSLMLPQIVDGVLPFLNDEHSRVQHAGCNALGQMSSDFAIIFQKKFHDKVMPALLQLLTNPKSARVQAHAGAALVNFFEDCPKSILSPYMDSVVNALEVVLKSTLNDLIEKGKKLVLEQVVVTLASLADSAQEKFIDYYDKFMPLLKHIIQHAIQPPLRLLRGKAIECVSLIGLAVGRDKFISDASEVMELLLKTQSANAPISEDDPQLSYMIAAWARICKILGTAFKPYLPFVMQPVLKAAAIKPEIAVLDSDDIKTVGSDDDWEFVNLGEKHNFGIRTTGLEEKATACQILSNVRIAASEILPYLLESAKVSGNAYVQEMWRYMLPPLLQALDSEPECEVLCEHMAAFSQCLDVLHYPCLPPDDLRTIVNILNKNLVGHYERSIEREAKRKEEDYDEVLEESLIKEDDEDNFMGILMYYCPHFVHLINSNRPWSDRQWSLCVFSDVIEHGGPACSRYQGYFLEPLLSSLKDENVDLRQTAAYTVGVLSQFGGPDFAKFCSECLPVLIEIINSPNSRSEENERATENAISAVTKFFVYNNSFINMEELLPAWISWLPVWEDQEEVICIYNFLCSLLETNNPLLLGNDNCNLPRIVQVVAETFRKEGIKASSDVGKRILTLIRDIQNNTGLFSICVSHLNPQQQQALCLALASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLT4</accession>
    <name>A0AAV4PLT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004920">
        <property type="protein sequence ID" value="GIX98507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7518" checksum="1560A8A4170AE352" modified="2024-11-27" version="1">MYVESNLKLACKLGFPEKLHFLAREDWIRLKDNKQWPRGGPCGISIEAAAEKGGDGRFGVNRLEDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PS35</accession>
    <name>A0AAV4PS35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_244101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005175">
        <property type="protein sequence ID" value="GIY00413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PS35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY00413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7980" checksum="B90804456BA3B870" modified="2024-11-27" version="1">MSHEAKTASSETPRMNSKAVYTSSKDTKVITSSIIREMFSGRRQFCVIMGNAKIFGITLISFPFSSKTVVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PY94</accession>
    <name>A0AAV4PY94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Centrosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CEP104</name>
        <name evidence="2" type="ORF">CEXT_661981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005363">
        <property type="protein sequence ID" value="GIY01720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PY94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048739">
        <property type="entry name" value="CEP104_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21038">
        <property type="entry name" value="CEP104_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomal protein CEP104 N-terminal" evidence="1">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10980" checksum="44ECC156BF47BF9B" modified="2024-11-27" version="1">MIKRIDFSIIKVTGEDDNFPAAELNNHRPVTKGWMSPKFCSYPQVIVIRLEMRARLCKFQVLSHPFSITSKLELHVGDVKPGLTEVLQNVAWEKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3C9</accession>
    <name>A0AAV4Q3C9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Probable cation-transporting ATPase 13A4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ATP13A4</name>
        <name evidence="15" type="ORF">CEXT_262931</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005601">
        <property type="protein sequence ID" value="GIY03601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3C9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000068">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="765"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="837"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY03601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="856" mass="95611" checksum="CD8DD337973C6C0E" modified="2024-11-27" version="1">MFQNSKSSKDLVPGDVLVLSQSPFVMFCDAVLLSGNCEKHSITKIPITDDSGSPFDVQTNKRNILSCGTEILLSRSTDTSGVRAIVFRTGFSTAKGELVRSILFPKPVALKLYSDLLKCMLIFFYFRNRSSYLHRSSLSLGRRPVRAERDHVLRAALPARRAHQHQRAGPEEAAEAGHLLPQLATSTSRGSGRRLLRQGTLTEDSLDILAVVPAQDRKFEMTVMNPGQISSENMVKAMATCHSLARIDEELRGYDLDIKMFKLTGWELQEPTPGENVPFEYVPPRIVFQKIFNEKKPSIAIVRIFPFESSLKRMSVITQTEGRSSFEVFLKGAPELSGVPLSERNSSSGCHGSSCVLFLSRLPNHSHCLQVLTRNHFLERSAEIAKISAQNLSKFRAGDYLERELHFLGFIVLENKLKAETIPALDTLKAANIRSVMVTGDNLLTAITVGKKCGIVEECDSVVIIKANMLSIRSRIAKETSISVVFGKQCHVALEGEAFNLLRMYNPELLEKVVLKGAIFARMLPEHKLHLIECFQNLGYHVGMCGDGANDCGALKTAHTGVSLSLAEASVAAPFTSTQQNVQCIPTLIREGRATLVSTFDSFRYMVCYSFTFLLAVLFLFWDGQRPSDGAYVTIDIILNLAPPFLCEMCSHAHGPRFDFFQSEPPQRAGVYRRSSRAEAYSVSSLRFLSFPSCSSRWRCIRSPSTTACSSPGTNLSPSTKKCLRPQRITRRNDDTHDQHDGLRHWGYDIRQRSSLQEHFFSNKLYVAVLVAEFLLVTYLTVSPPQFMVDFLNFKRAPVSSFHLKLYALTLGVNTSFNAFWVVTWYQPFENGEDPFGSTKTQAKTLPRKLASTESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8Z6</accession>
    <name>A0AAV4Q8Z6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_267521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005968">
        <property type="protein sequence ID" value="GIY06503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8Z6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15754" checksum="9A630C61F3554925" modified="2024-11-27" version="1">MEEVSKRKFLYQENRVQEESREKDFCKKKKKKQNRGRKKVSTNKTRIEEESSRNFSAKKAEFRKVSNKKDSVQRKQNRRRKQKVLFKENRIAVSKKLSTKHKGYLPRKHNSGKNPTEKVLYKEKQNRGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAA8</accession>
    <name>A0AAV4QAA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_515091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005906">
        <property type="protein sequence ID" value="GIY05941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18959" checksum="1A4F350A54793920" modified="2024-11-27" version="1">MTLPVSFFLPKYDKIDLHKLWRKRTHRCMESLSYNSSNQSRTPKYLPARQIPSNFSYVAAIRSSPFQPPSPQVSQNFNQALTNATAQYLNEGSRYGDRGFPLNHPLSSMKNDLLSEDSRRTKKLSWKTILILQPFLKPYFFLDGLKKLEKRWAKCIELKGVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QES9</accession>
    <name>A0AAV4QES9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_199791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005976">
        <property type="protein sequence ID" value="GIY06581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QES9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16740" checksum="32538FE73CE8F345" modified="2024-11-27" version="1">MSSEKNSSSELFLACERTFRFSGVTRDPLRQLKCIKIENITAYFCQEDNDDVIEALYSVLTSLFSLMFDKWAISKKTIPVKLRLFIGVFHRQIGHLNQFVDSLPQVRTRETSPGGRRASAFLGQSDGLSGVKLRAVTEGEIENCKSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QG31</accession>
    <name>A0AAV4QG31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_313761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006170">
        <property type="protein sequence ID" value="GIY07891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QG31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8082" checksum="DD0210F6BBEC9A8C" modified="2024-11-27" version="1">MDPQGHALGKGMAETLSRSLRWTLTLCNMLCHPRCIIWPSNRHTYCAPVKTADGSHCSFCQHMQREYTACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVP4</accession>
    <name>A0AAV4QVP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_171681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006918">
        <property type="protein sequence ID" value="GIY13339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="21411" checksum="D5D6175538EE5338" modified="2024-11-27" version="1">MTPTKQLNELTDTNLRSICNANKLFRKRLPRLFGTKSFGRGDDCASLLRRLHEFIHKNHIFSPSATNTNRTASSAALTTVQIQSGARHRAGVTITGELVYISEKFFIIHIDNFSKQEQIEYSVQTRLREEGWNRFSGKSTWRRYLNNLLNCYKVEFCFERMFIVNAFRRLPDVELQIVLTGDKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QWJ8</accession>
    <name>A0AAV4QWJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">X975_23911</name>
        <name evidence="4" type="ORF">CEXT_12111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007032">
        <property type="protein sequence ID" value="GIY14008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QWJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:DNA transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057667">
        <property type="entry name" value="HTH_SB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002492">
        <property type="entry name" value="Transposase_Tc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25787">
        <property type="entry name" value="HTH_SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01498">
        <property type="entry name" value="HTH_Tnp_Tc3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sleeping Beauty transposase HTH" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Transposase Tc1-like" evidence="2">
        <location>
            <begin position="69"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY14008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="207" mass="24001" checksum="497F46A82AF5F181" modified="2024-11-27" version="1">MPRSSELSYFEKGIIIGYHKCGRSLRDISSYLKHPKSTVAYVIKKWKVSGDCRNVPRVGRPTKLGDRDRRVLTREIRKNRNQPMALIREEFQQASGSIVSMNTIRKEAHLHGFHGRAAAHKPLITKSNRAARLMWCKAHRNWTVEQWKWILWSDESRFILPFGWQGLASACLENVSCPEQSSSRRRWNYGLGVFLLVWTGTLGPHSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R0N1</accession>
    <name>A0AAV4R0N1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_732621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007051">
        <property type="protein sequence ID" value="GIY14139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R0N1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12682" checksum="97E07A20D0E298A2" modified="2024-11-27" version="1">MINCEIKSLRKDVVVNASNRNVEHEFGKSVFVERQTFGPDSFAIRTVVMQQMKLFPTEILGVYYKALTVIINLKEHPQRAFRPTVISGLSPHIDTTVLFSCLFSNLNPLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1I7</accession>
    <name>A0AAV4R1I7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_732831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007051">
        <property type="protein sequence ID" value="GIY14180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R1I7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22957" checksum="4A0AA9205B4DB8CC" modified="2024-11-27" version="1">MDNNCVSCMTFSEPLMQPNNNAFFYLLTAMPTILKDKNQRPSEASVVCEQKTDRMKIDYFLLDYVLPAEEREIPGRLRASDRRRRSPGMSAGHPSPTLSAEFEKCDRTKSPGGRTKAHLSSRKKDSTRIGFSSEKHDRRMFPANFSSRIPSVKYKINKRQRKNRAPTSSRSDNEMPEMERKHLRWAKNARLRRREFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R1T1</accession>
    <name>A0AAV4R1T1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FYVE and coiled-coil domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FYCO1</name>
        <name evidence="8" type="ORF">CEXT_688991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007035">
        <property type="protein sequence ID" value="GIY14028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15730">
        <property type="entry name" value="FYVE_EEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46753">
        <property type="entry name" value="FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46753:SF3">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RUN" evidence="7">
        <location>
            <begin position="33"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="1031"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="473"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="823"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="894"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="978"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY14028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1296" mass="148578" checksum="435BBABD078E0322" modified="2024-11-27" version="1">MASCTVTSKALLDIEACIVELKKQFSVEKIPINDDCTVLHQLEEKLETILLLGLKREWWCFWSKKRSYWDYIVTCFSVSKRLHEGIKFVKSNSELKSSLGRGRALIRFCFMQKCLADTLQSCFIDHKTTRDFYSDRCLPLQPKRKVFVPFGNEVSFMNMDSGSNDFSSKISNEIEIHDTDNDVKADCEMTNNHNANSINVTKNCVEDIDTELNLHSSSNLKTQCSTLNDKSNLIDVSNSEISASNISSNLELKSLESILTVCDSSALTNLNFTKSFLQENIDNLLETEINPFHPDISNSLKKLILEMKAVLNNLENSINLSIKDPTALSQITCLKIIRDCVEKSFLINSSVKDNESLYDRICFLKDKLHSFGLLKVQTENNVDFKNNSKLLDESITNAIVVPECINFEHSEDMGNNFLESLTILRNSSTKLHTLNNQASSLKLLLDSSHKLNENLISRIQDQELHMKGITKQLEEAHNLLSVMKKQHQKLQSAENIVKYDLQEKRKLLTKLKQQLETTRENCNLVRLKNSKSEAEWQTLRKEFVQRNKQNSEESGFIDDKGIEDQTSAVVNSVYDCNINDNVPDNVLPLDNNDIETKYELKKNRLQLLEEQCQILCTNLKNSSKKRKEIDYRLESWCKAIESSHKENSHKLTEILSSEEGKSTIDESTSEKIIIDSNSDVDSSLSSPEIGSLNSNCCSFIPQDSNIISTDLSISLQSLKNDEFIPSINLECNQSKSPFEEENSIHSDHILKEIGDNSSESIENAASSCALVESVEFFKEAKENQMQTLIQSTSDVLTQVKPYEIPCSYEESQLVQSPSCNSTFEDLSELVSKLEEEKKMLQLKCQDLEIKIVMISDEFNQKIQELKLSEAAKKQEVVALQFQLNSEVLKYESIIKEFSNNNEGLKEMKQKVSDQEQLIFTLEEALAEIQVEREGEKEHQWEQLQDIQLALSTREEECVSLSSKMVQLEEFKMSNLKDREILENEIMHLRNDTKELQKKVIRLLKEKDILWKANDRLRYFHKMQIDDRWIDDHEVSECLGCRSQFSFLLRKHHCRQCGRIFCSSCSNNWLSTPSSRRQIRVCNECYMHRIEIKTDVRRDSNVQYCEESEDEAVVDDMSLNLNRSSSLSSEIHSTIADSIISLPAMHVTNLKQKSHFTSAPELHFSLDNQDILKRSFLNESILPSHMEIIENDINGNILIKANDEAILPILNEVNSTSISWKFEPPCEAIPIMLVYEDATHCSQQTVMHQSSCETEGVIHLCLPGLYKFHFDNKSRPSSMLVHYSFKANILKEQEITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R288</accession>
    <name>A0AAV4R288_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_775601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007084">
        <property type="protein sequence ID" value="GIY14435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R288"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14432" checksum="1D3721D38A8C6C50" modified="2024-11-27" version="1">MTYEYEILLDMRVAPEDNGGGISHLWKQGGSEFSIYVWQGPCVSFVYATDLVFYGIVFHLFTPGTSSYVTIMVLNYPDLYIVVNVRRFMATEDNGGGISRLWKKFNAKKEINKRHFVFVTLNETGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8E0</accession>
    <name>A0AAV4R8E0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_731641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007440">
        <property type="protein sequence ID" value="GIY16911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8E0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13943" checksum="B9DE77C80CA5E503" modified="2024-11-27" version="1">MCFSTITRPDSILVNDISRAGDFRKKGRGGERWLEHPRDSIDEDFKRVGGVNWGCRIHAIYQQGSEDSMQVPSKNPLQKVDAITHNSDKFVVGSRGNESGFFSEAVDVRRFVAKLLSFFIHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R948</accession>
    <name>A0AAV4R948_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_586521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007679">
        <property type="protein sequence ID" value="GIY18833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R948"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="17018" checksum="24D7A2492C5A4876" modified="2024-11-27" version="1">MADRPSDPFDDAPAAILRLSCLLRSLTFSSTLFFLLLFFGVISTLSLTGLRIFNILRFRGEEQRCLKRRFYLCSSLPYVCVATSPTRFDFASLWREREREKNTLRSSSYCSSIALEFIEIFTNISQWTWFRKNKSTLWVGNGKNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9G3</accession>
    <name>A0AAV4R9G3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_707061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007492">
        <property type="protein sequence ID" value="GIY17286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9G3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11017" checksum="12C909A9A32961BC" modified="2024-11-27" version="1">MAAYKLLLASLILWVLKLDGPRLHIPMSLYYIPYAYILNWTFFIVIAGEVHEQDVVFKKPIALNLLKSPENLKKRQLNLLNSLKLKIAISAWGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBZ9</accession>
    <name>A0AAV4RBZ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RFC2</name>
        <name evidence="10" type="ORF">CEXT_114001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007763">
        <property type="protein sequence ID" value="GIY19498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000006">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000012">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000107">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF5">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="65"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY19498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="351" mass="39569" checksum="E11DA5CEFB8DF408" modified="2024-11-27" version="1">MSATEDVEMIDESEKMTEKKKAENEKTKENGHIPWVEKYRPKTFKEIVGNEEAVQRFEVFSREGNIPNVILAGPPGVGKTTTILCLAKIMLGPCFKEAVMELNASNDRGIDVVRNKIKMFAQQKVTLPKGKHKIIILDEADSMTEGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAMVRFGKLSDLQILSKIIDVCKAENVGYTDDGLEALIFTAQGDMRQALNNLQSTYSGFGHVSSEYVFKVCDEPHPLLIKDMLKHCADSKLDEAYKILLHLWKLGYACEDIISNIFRVCKTHEMPEYLKLEFIKEIGLTHLRIIQGVHSLLQLSGLLARLCKKSRSTPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFH9</accession>
    <name>A0AAV4RFH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_36441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007758">
        <property type="protein sequence ID" value="GIY19446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8324" checksum="EE85444BA29C8BE9" modified="2024-11-27" version="1">MSCNILRVIPLIDALETVAKCHLLYPPQTDQKFKITKPDVPKFSRGQSPLFRSVSSTHKKTPENAEGGDIRSNGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RIL4</accession>
    <name>A0AAV4RIL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_569621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007868">
        <property type="protein sequence ID" value="GIY20364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RIL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9590" checksum="CAE259647D906C20" modified="2024-11-27" version="1">MGFGRRKLSLTAVLANIYDGLDAGKSSLLGPHQASPLDVLTRTGIRFRFVKISCKSIGDRSSPKLGLAPASYQQWRFVVISFCSDCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUX0</accession>
    <name>A0AAV4RUX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_583841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008569">
        <property type="protein sequence ID" value="GIY25678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY25678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="17261" checksum="FCC606C0CFC2633A" modified="2024-11-27" version="1">MNSDEIKYSTCMVVSLYRKFVCWWTVVDATSRVLKSNFKSIVYYLEAHCRSLANFLRFENVITYHLNVFLNSTELVKENLNALTREVSNLIDLAASNNPVSEDNFFDVYDIICELQEDLKENFRDCKKHFKDFCFIRQTILDHFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVK6</accession>
    <name>A0AAV4RVK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Irregular chiasm C-roughest protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rst_0</name>
        <name evidence="2" type="ORF">CEXT_142961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008440">
        <property type="protein sequence ID" value="GIY24714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="22331" checksum="167322F6E962EAEF" modified="2024-11-27" version="1">MRTTGVRKTKQSDSASSGDSDFKAEIRTASSLSNNEHDRSWEESSDRAQDNNIFKYNPNDYPETNFPPKPESQVNNGYIPYVDYTRDYTPPAVPPTGGVRDSGLYGSPPQSLSDLSHTVDPRYRAGYANPYLRNSASNLPLPPPQGGQVFVTSTWGGHHTPSPTSPAAAGQQPSSQQSQNPAQNRYITAQQGQTHLKPGTLATHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RW35</accession>
    <name>A0AAV4RW35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_566271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008484">
        <property type="protein sequence ID" value="GIY25041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RW35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15184" checksum="7434F53592727ED8" modified="2024-11-27" version="1">MVSNTTVLLLQIPTHKELRSLHSPSPPGADNAAGAASPTAQLPMTSSFNGGEKGRAQRRNADTGYNTFTPTRKRQLKRWALYDELLKSYLQQLPFLISGSEVGASEFNLQHLLQSSAYNEWPNPDFIKSLPTLSPSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0Q2</accession>
    <name>A0AAV4S0Q2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_5311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008907">
        <property type="protein sequence ID" value="GIY28118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0Q2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9465" checksum="9BAAE4C4AE2D1D6D" modified="2024-11-27" version="1">MLDGVLGRNGINNGYQNVVVRTDRCDKSAGNQAISSLPIHDGAIVNKKGAFGRALMNLGVIELSVPISTTLNERRFSWNPNSLGRKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1T1</accession>
    <name>A0AAV4S1T1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_457481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008884">
        <property type="protein sequence ID" value="GIY27949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1T1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="44" mass="4934" checksum="E9294CDF43613FC4" modified="2024-11-27" version="1" fragment="single">MDNSSDSYSGNGSNIDTDFDPHHCLSDSKELRAECKDRPFSNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2T5</accession>
    <name>A0AAV4S2T5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_304711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008724">
        <property type="protein sequence ID" value="GIY26712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2T5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048407">
        <property type="entry name" value="Dumpy_DPY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21164">
        <property type="entry name" value="Dumpy_DPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="10812" checksum="0E3FC76BE02BCF48" modified="2024-11-27" version="1">MNLKFGLSLYGIRPETCGTGAPATGYSGSVLKKFIITIKLDSCPTGFICGCRIASECRLTEACINNQCRDPCASPTACGTNARCQTTPTPDYVLVSSRTHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3P0</accession>
    <name>A0AAV4S3P0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_56593_1</name>
        <name evidence="1" type="ORF">CEXT_257441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009024">
        <property type="protein sequence ID" value="GIY29108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3P0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16420" checksum="30683E18D2ADE5E4" modified="2024-11-27" version="1">MYLKKLKDKEEIRKLLIAQRAEELLRKSSLPFSPKHIPRSHSLFNINDCTKKGNVNVTKQTIEAITDRLYTIKCQETIENWNNKVNDLWSDETSDSKQNCNMQTNKNCDKRKKVPHSALPFYNFPVRMTTAASLRDNHIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SEC7</accession>
    <name>A0AAV4SEC7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_168161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009274">
        <property type="protein sequence ID" value="GIY30762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SEC7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10124" checksum="04FC7D9031347DF6" modified="2024-11-27" version="1">MDDTVQDNFYTDRDVTHAAKDSYVDRRSATNINTPASSESPKPLSTNRRVAVATVSSFSSRVVFRIHTVISSKKENQGGENEIPCFRVSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLP6</accession>
    <name>A0AAV4SLP6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_86881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009835">
        <property type="protein sequence ID" value="GIY34939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10312" checksum="0DD12B7F40244333" modified="2024-11-27" version="1">MSKKLLTTSGSLSLPHTRSLSAAISKVLQSKHFPTLLLNQISGNAFAFSPTDNVKSIMDKEKSATTLPMGKNATGPIHNNPYIDNSALTTRLQTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQ64</accession>
    <name>A0AAV4SQ64_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glassin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_327511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009798">
        <property type="protein sequence ID" value="GIY34707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQ64"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY34707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13934" checksum="5812832CAECC47BF" modified="2024-11-27" version="1">MDLNTDTNMEMVMGMFREAMVSLITGEFTEVHYVADHHGFRAQVKTNEPGTANQDPAHVHLHSNAHHALHHDGHHGHHHHDHHHGHHGHHHQDHHHGHQHHGHAHMYHHQDHHHHGHHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUA6</accession>
    <name>A0AAV4SUA6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ZP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_133694_1</name>
        <name evidence="2" type="ORF">CEXT_487881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010201">
        <property type="protein sequence ID" value="GIY37665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZP" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12637" checksum="580731027357E9FC" modified="2024-11-27" version="1" fragment="single">LYAGSTNGESLFLIDSSGCPTDATIFPALQLDPTDHKSLLSTFKAFRFPSSGMVNFEVSKLDSVKEKCEQNKFSFLDDEDVYFDHDNYDSIRAVVQEEPQSMVLSVERRLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7K4</accession>
    <name>A0AAV4T7K4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010530">
        <property type="protein sequence ID" value="GIY39918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7K4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15103" checksum="BD29B5EE765EE8AD" modified="2024-11-27" version="1">MYHTCSRAFQSDGHDDPSIRGRTSGTNILVSNIPWKFGLIHVNMWYNNVFSITLCSHSMMRGDTDIIRITEKYDANIASVGVQLVKVPGLILGQRGIPNQELSVGKNETIELCTPFFFVQLKRFQAQFKRLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBS6</accession>
    <name>A0AAV4TBS6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_631901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010715">
        <property type="protein sequence ID" value="GIY41418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11066" checksum="A4B120302AD30309" modified="2024-11-27" version="1">MDIQLTTIKGTLFPPSRIPLYESAREACQRNGLKSLMLVSFSDGDYVHTRLAEAVVTVRMSTKAESLHQAFSFQHISNPFCFAFFTLQGIGSPHRRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TC23</accession>
    <name>A0AAV4TC23_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_678212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010834">
        <property type="protein sequence ID" value="GIY42320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TC23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043652163" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="10082" checksum="879414AF074A18D3" modified="2024-11-27" version="1">MRASKLFFLFCFLFVLTRTQAQFFTKTTNSIPRLEGQINPFLPNLVRHVAKQLHFNAMKSELEAIELRELPMEKQRENQNQVGNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGA0</accession>
    <name>A0AAV4TGA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_374131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011144">
        <property type="protein sequence ID" value="GIY44451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15323" checksum="73092830F3372E30" modified="2024-11-27" version="1">MSSRTYLPPSKSECALHFCNSKHPSLAWSVAVSSSACGSERRNRKGFDFKSSPSSIPKAEISQHPPHLFPPFILRELEVKNGKGTSHSVLCPGIKYPPGHISKSKSECALHFCNSKTSALAWSVAVLSVVQERRNRKGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJY0</accession>
    <name>A0AAV4TJY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Brain tumor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">brat</name>
        <name evidence="3" type="ORF">CEXT_790261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011354">
        <property type="protein sequence ID" value="GIY46034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050952">
        <property type="entry name" value="TRIM-NHL_E3_ligases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24104:SF41">
        <property type="entry name" value="BRAIN TUMOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24104">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="4"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="42"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY46034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15091" checksum="AE9DFED4025F342D" modified="2024-11-27" version="1">MSYKFGCSKHLEFPNGVVVNDKQEIFISDNRAHCVKVFNYDGSFLRQIGGEGLTNYPIGVCINQSGEILVADNHNNFNITIFTQAGDLVNASESKVKHAQCFDVALMDDGSVVLASKDYRLYIYRYVQAPGLSIAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNJ8</accession>
    <name>A0AAV4TNJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exonuclease mut-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AAEL005527_1</name>
        <name evidence="1" type="ORF">CEXT_198651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011663">
        <property type="protein sequence ID" value="GIY48015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="490" mass="57441" checksum="1EB8749A0C93B4E4" modified="2024-11-27" version="1">MFCYCRLLRRVLLHNKRGNSSYLKFSCTNYVHSESLSINSSKNVQERNPSLLAVREVRTLEFFWRKQRNGKRFKSIIDDYFLNNEGSSSHVLDLLRAACYSSRCSSGLILSLLINLNDVINRKGEFSPSLDEKKEALQSALTYQSYDIIQEVCKAFKIVEHSHCFKEFINNLISEQKLIQACYCITALRLQHEFDIEKVNIFPLLLEGKIHPVVMCIENHPDVQLRIVKKLDNLLGEENIGTINYKPSLNSRKIYKVLNKLMNILKIPSENYKYVHHIRSRGAINILIKRRSDQSVSEEAWKEMVMSIIGDDDQLKEYLIFKLMQQNDKETALEMVENLNMIDFDVTKYDLAIGEETEIDNAMDKEEFEDLSKQFEKENNSGHLMFPLSASDIKYTDNVEKFTEFIDDILKYNIAGIDTEWKPQFNLSPERLALMQIAIHDRVYILDLISLNDCLSEEHWDKLFGRLFWQSKNYKIRMWNYDGYFIDSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNV2</accession>
    <name>A0AAV4TNV2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011614">
        <property type="protein sequence ID" value="GIY47734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNV2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8427" checksum="0AA97EEDCB9C455B" modified="2024-11-27" version="1">MPGLFGSGTLPKRCHGPRFVGSVVSEDYERNSATVSLPRVDSELANNQASPTMGVKNIKFSAEIRVESVINSLTNTYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQ57</accession>
    <name>A0AAV4TQ57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_519601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011558">
        <property type="protein sequence ID" value="GIY47274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQ57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12451" checksum="9F494DC303FE6114" modified="2024-11-27" version="1">MQLCEFERIVRMLSQNAMLNDDDVVELENGERKASRVIESHSGRPAVLGHINRKTWVHGDVGFDVGCGPEEDIDLRRAEHERRNRGNPCCSLPTAWSGGERMGGGGCRLTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB10</accession>
    <name>A0AAV4UB10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_296351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012587">
        <property type="protein sequence ID" value="GIY54985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="19145" checksum="8D3AEF3C98ACFA0B" modified="2024-11-27" version="1">MTNLKIPEKLKPDLIFVLKSMVLVTCKWFMDHSDILEPDFDDVSSFHWRCEGTIDRVKTAQALVRREDAPVTMRLRFATCYCLEEDVRRLQTMASMTMRLEFASPYCLEEDVLRLQRRCSPGMLCNRAELCNLISTDWMRDWCKYTGTHNCRSFGSVALTRGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UC24</accession>
    <name>A0AAV4UC24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_536081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012630">
        <property type="protein sequence ID" value="GIY55307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UC24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9947" checksum="2323AFC049D37052" modified="2024-11-27" version="1">MQNYEPVKITRCSPPSPRKLSPEKMRATPSFRCCRHGGFTLTILHTMNNVCGLERGSANLSEEISFLSHSCSGDLLNLYNTGNKSVSSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UL62</accession>
    <name>A0AAV4UL62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_467061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013084">
        <property type="protein sequence ID" value="GIY58657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UL62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="257" mass="29169" checksum="0E40E480BEBF4113" modified="2024-11-27" version="1">MWVITSFSIALSLAFPMFFSKPTLQAKETICMFDQVQKSGAALSSPFPLGTAKGALFACIHASICKEDGRQGCVTIPGEENEQPPPSPLSTSSSSQEPEWSLRSVSSNDIHPIPSQNRTELKIKKKDEHEPSSPGNIRSPRERENKGKRNKNRDAHTHTHNKEGKKAVKETAGFSGRAKSPGEGARLFDWEWIRWGKERVLRQIMNPASVVDLTVFFCKQEDSTKPLVINRSFFFFYNIFFFFFEFGEWWEKKALFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQ95</accession>
    <name>A0AAV4UQ95_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013258">
        <property type="protein sequence ID" value="GIY59949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UQ95"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16546" checksum="9A9833BFE2272E36" modified="2024-11-27" version="1">MATNRRVFWDFRSLIGMTASVLLRRISLSEKRKQQKRRGFSQKFRERKKTQNCRRPILSLKLAPPFHHINVCDDPFPTEGGWEGEREKARIPTPKYCIPLYLCCSVIECDVAPICLKSSHFPGLNKKKKRWQPIAGNSGIPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URV5</accession>
    <name>A0AAV4URV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_45051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013332">
        <property type="protein sequence ID" value="GIY60481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17384" checksum="CA182DA403C7DD31" modified="2024-11-27" version="1">MKMMLSLLVNSRFLDSEDPLRIEKQFQCFPGSSFSRPIHARLEDTRRPRGSSPLAPNCTESDAASMRCQPPMKRGSAQSNRSMCCSFGILNSSHFHNPCTPAEEGSSILHSYSSKIKRRRRKEKKEGDVVRRSVEEELDGGNLPSLRMPPSSGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUX4</accession>
    <name>A0AAV4UUX4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_399951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013473">
        <property type="protein sequence ID" value="GIY61490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="15546" checksum="CFAAE783BDEB6DBB" modified="2024-11-27" version="1">MASFGEFLFSDPEPMEWEDALVEEPMDWLQAEEPMEWEETPLEVSQPSTSKVSLPLTKSEEPKVPSEGTSVSSKVRTVLRARVPVPQKVGLPSCLKVDSPGLLEDSAHPRKVKRRPSFDSSEEEEVADDHKRRACLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWJ7</accession>
    <name>A0AAV4UWJ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Forkhead box protein N3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FOXN3</name>
        <name evidence="8" type="ORF">CEXT_727161</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013514">
        <property type="protein sequence ID" value="GIY61774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWJ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047119">
        <property type="entry name" value="FOXN2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13962:SF22">
        <property type="entry name" value="FORKHEAD BOX PROTEIN N3-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13962">
        <property type="entry name" value="FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="7">
        <location>
            <begin position="56"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="56"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY61774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11518" checksum="8B2CF4BC55A63AF3" modified="2024-11-27" version="1">MGSYGIEGEEVLSDTLSSDCLDDAAVNLTVDEEGEQNVESLPAHSPYNPAVHTTSKPPYSFSCLIFMAIEDSINKALPVKDIYSWILNRFPYFQNAPTGWKNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYR6</accession>
    <name>A0AAV4UYR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_2141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013698">
        <property type="protein sequence ID" value="GIY63047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9971" checksum="316190B7FA8D3B68" modified="2024-11-27" version="1">MTTTSQQKLAALKSAHPGEMSLHKDLKFTSSISCCFLQNFGEGGDRSGTTRKSDDKSQKHPCTEKGRERVEKMEYIFLGDKMLKPRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8Q6</accession>
    <name>A0AAV4V8Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_166031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014045">
        <property type="protein sequence ID" value="GIY65895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12112" checksum="04AC00D5E178FB06" modified="2024-11-27" version="1">MDVCITMELEWTPKTTCMSGAKPKTCPTGRYPKDASCQEYLPVSEEKRSPPDPLFVRVLGGTFSASTTLPPPGEKQRNHLSTTLPLPMRVVGSGHPFHPSQPSVPPPRLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEX3</accession>
    <name>A0AAV4VEX3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Single domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_607191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014450">
        <property type="protein sequence ID" value="GIY68830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029277">
        <property type="entry name" value="SVWC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15430">
        <property type="entry name" value="SVWC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Single" evidence="3">
        <location>
            <begin position="24"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY68830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9254" checksum="279A32C7659426C1" modified="2024-11-27" version="1">MENQFLKQDFYLALGFCEEERYGRIPVGGVGYDDERCERIKCTQGWYSGEGCSPVAMPGFPGCQLVRGKGHYSKCCKQLICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VF18</accession>
    <name>A0AAV4VF18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch-like protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Klhl20_2</name>
        <name evidence="3" type="ORF">CEXT_145961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014472">
        <property type="protein sequence ID" value="GIY68961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VF18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632:SF3">
        <property type="entry name" value="KELCH-LIKE PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632">
        <property type="entry name" value="LD33804P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY68961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="270" mass="30991" checksum="2E5E7DA5224BAB16" modified="2024-11-27" version="1">MLKREETVFEAVLLWLNQDLAARSEDFHQCQKLIEEAKLYNLLPDRRHQTASVRHRPRRSFGISEVVVAVGGGEDDKVVLRSVECFDPVNDKWLTLSCLPFAISKHGVVVTGQNILYVAGGEYPDGTASRSLWKYDPIFDQWQEMSAMNVERSELGSRACVVNNLIYVIGGWHASTENTNKVEYYDPVKNEWRFCKPMLERRYQPGVAVVDGKIYVSGGEEGWDRYHDTVEYYDPQTDQWLIAGVMQTARSWLCCGTLRLNVDFRIKEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VG80</accession>
    <name>A0AAV4VG80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biotinidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BTD_1</name>
        <name evidence="2" type="ORF">CEXT_691881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014476">
        <property type="protein sequence ID" value="GIY69009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VG80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043957">
        <property type="entry name" value="Vanin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19018">
        <property type="entry name" value="Vanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vanin C-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8866" checksum="1CBFF788A24425C6" modified="2024-11-27" version="1">MKSKTSFKHIHLKGNFSSEIVYPSVLQSGMRLVPRSVWDHHHHDNKRDIHVDATKGADILVVGMKGRCFDRDPPYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMF6</accession>
    <name>A0AAV4VMF6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_774791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014743">
        <property type="protein sequence ID" value="GIY71026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11549" checksum="CB844662F1818E47" modified="2024-11-27" version="1">MCRSAFHQLSNTPDDSSKDSTPHVAVTCEHQPSLYKNHHQCKRRLEVFKKACHLMTMHKEDASVGNTRLPLTSKKKRMTEFVDQRALVERPRAPTDHGGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0S2</accession>
    <name>A0AAV4W0S2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_380891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015464">
        <property type="protein sequence ID" value="GIY76297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0S2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12810" checksum="845959AFCDDC04E1" modified="2024-11-27" version="1">MPILLSNGLIETINIQPTSQTTMNLLAQHKSSHAIKNSHPTSKSQASLNQNKSLARLMPIQLMPILLSNGLIETINLQSTSQTTMNLLPQHKSSHAIKNSHPTSKSQASLNALIPIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W543</accession>
    <name>A0AAV4W543_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_112481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015519">
        <property type="protein sequence ID" value="GIY76713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W543"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8624" checksum="C65DAB8B3593078F" modified="2024-11-27" version="1">MLMKTDSQNATKDEGNFPLQLFKALQKHEAAEIQLPCRNYSNEATESQDNCQGGKARQVFLTFPTRNKSRTRMRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEA5</accession>
    <name>A0AAV4WEA5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_781631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016092">
        <property type="protein sequence ID" value="GIY81186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8071" checksum="B999D944B0E764FE" modified="2024-11-27" version="1">MPLQNKREKQPAEQQGQSIHTYQETFEYSDIQKRDIRIGKLGSTESHSNGRSPIVFRDIDSNSFPCSTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WF43</accession>
    <name>A0AAV4WF43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methylosome protein 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">WDR77</name>
        <name evidence="6" type="ORF">CEXT_642101</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016015">
        <property type="protein sequence ID" value="GIY80474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WF43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034709">
        <property type="term" value="C:methylosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007309">
        <property type="term" value="P:oocyte axis specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052139">
        <property type="entry name" value="Methylosome_Comp_WDR77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46853">
        <property type="entry name" value="METHYLOSOME PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46853:SF1">
        <property type="entry name" value="METHYLOSOME PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY80474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="318" mass="34849" checksum="5141AA7A9B4BDDC0" modified="2024-11-27" version="1">MSGAVPAVVEQHLDAIHCNSDGKILLASSNLTGRYWNGSLWCFRNVEDAPYVEKCLTGIDVSSGIADMVSLDQNKIALGLDSGGLEVYKLETEGETSHFAWTFGVCEHDDFITSLSVNSDKTNLVSVGADKCVKIWNIETWGTTATFRPVHGGIIWQVACSSGDPNLFLTCGQDGKILLFDLRLPKPATLIDNSSLKDEPTALAWKPTSSTAFAVGDASGLVIMKDTRSMGTISSWEAHKRRICRLSFPRNQSWLASCADDSDVCITDVEGEKPILMYKDDSHQDFVRGLTWSESNELISCGWDKKVISHICKKDETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGS0</accession>
    <name>A0AAV4WGS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_83960_1</name>
        <name evidence="3" type="ORF">CEXT_579151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016130">
        <property type="protein sequence ID" value="GIY81463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="91"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY81463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="262" mass="29776" checksum="4EDC06A25F2072B6" modified="2024-11-27" version="1">MGHPGLGRVMMFGVVEGLQKTYAVSADEMERIECQVDADPSKVDFKWSFSNTADRHYNVSFTSAGLRSVATYTPRSARDYGTLYWGKEFCPPETLQNCTSTNVTMTSVTILCVRGPRQDPDLKYNLEMFMYHSHEMIYQTSSLRPYFVITNLSPGTEFLFVVYAVNHNGKSSPVMVRVWTRRSPTEERVFLEENSTEDPSIDHSWIGPSLLIAVALCCFLMFTGAAIWSKLRGGPGCQKYKNMTRLKAFFTIWKGKHHDINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHT5</accession>
    <name>A0AAV4WHT5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="2">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GlyP</name>
        <name evidence="3" type="ORF">CEXT_241971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01016247">
        <property type="protein sequence ID" value="GIY82416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF13">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY82416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9830" checksum="66F142A4261A67E7" modified="2024-11-27" version="1">MNGAITIGTLDGANIEMKEEMGDDNIFIFGMNVGEVENLKKKGYNAWDYYHNSPDLKEAINQISDGYFYPKDPYAFQKSRQHTNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WKK4</accession>
    <name>A0AAV4WKK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_201011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016234">
        <property type="protein sequence ID" value="GIY82309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WKK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12018" checksum="EC0BC537819C0BEB" modified="2024-11-27" version="1">MKRSRKMAPTISKRNKPDEVIETSNPYDVFEVEEITIDDPSNDITSASSMQNSVNTNGISSGMNSMHIDALEEFNSKNKPGYVPLIFVDRIDNCKQLLNYLQKAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WNE8</accession>
    <name>A0AAV4WNE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_563091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016360">
        <property type="protein sequence ID" value="GIY83269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WNE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="254" mass="28149" checksum="464FE3EDDAFE8DF9" modified="2024-11-27" version="1">MHKRAVASVWNGMMPDAFGNELFALPSVHDQVCRRIRKRYWNGRFPLAALGAACHYRRSIPALSACSQYTCQEPICEILGALFAGVVRYSNHPGSDSLAITPQIILIIVCGIIMRKRAVASVWNGMMPNAFGNEVIGLPSVHDQPILIGPLLCCYRYSSRLQRWVLHAVIADLSQHCRRALSILVREPICQILGALSARAVRNSNHPGPDSPCNYAEIILIIVCVDMEWSYGRCFRERGLCSAIGTRSGMAENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WX62</accession>
    <name>A0AAV4WX62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_665511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016783">
        <property type="protein sequence ID" value="GIY86355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WX62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13345" checksum="BB5E18D5227DDFB7" modified="2024-11-27" version="1">MICISTILVFQDDICFVALCFTLWLVLTSYPNFGIQRLQSDMRFLAIPFIWNTTHRPNPPCSASTSCSGQVAQLLVGILQVRGSHSLSVDRGWKVTDDPQHIGRRCKQEYSVLTISPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXK6</accession>
    <name>A0AAV4WXK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_715271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016948">
        <property type="protein sequence ID" value="GIY87522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13084" checksum="A6FC8B3483F53CD6" modified="2024-11-27" version="1">MFLVKANLIPLFMKIAQEQGLESCIQYTCISHPSKYGTPFKSLKGGKFCSWPGSANVSPLEVDRQRRKSIMEDTQLVHQITIDSAKMEEVENCSPPEKGNQWVPQNFRTTFISFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WZ58</accession>
    <name>A0AAV4WZ58_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_307281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016890">
        <property type="protein sequence ID" value="GIY87121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WZ58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY87121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="123" mass="13748" checksum="252CB39D239E9CDB" modified="2024-11-27" version="1">MKSTNLLRTNKLDIKKIRYPTMETDQNEAKSPVLVIKVILATICMFGAFTGFLLSIWKDNYYAVPGCLILELVCVGSIYYLVSAVTLKQGFYPEKDGFYFALLPCGLANVFSLCGWSTIPENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBW1</accession>
    <name>A0AAV4XBW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_194086_1</name>
        <name evidence="1" type="ORF">CEXT_742612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000038">
        <property type="protein sequence ID" value="GIY91670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051077">
        <property type="entry name" value="Ca-dependent_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24024">
        <property type="entry name" value="PULMONARY SURFACTANT-ASSOCIATED PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24024:SF18">
        <property type="entry name" value="SHORT-CHAIN COLLAGEN C4-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="376" mass="42301" checksum="18AF4792700B54C4" modified="2024-11-27" version="1">MEISYYATVPLKGVPNTIEGLRNLVSDFDEHVKEVEGGWGVPIRVELMELASLGGENSSEFRFIKDRALESELTDLEHEFDDLRKASTMLTEWYRTLPTSITPDEEKEVNKLYMRIQKILRPYYDSIGKLNIEEGPEKQVKGAREAYKEGKISALPGKFTKEFMRLKKKINISEKKMYGTGTEKKMYGTGTGTYTRWGSKECPSSPMMFKLHTGYMASTTSRGIGGGSDYLCLPDNPEFSENQPDFGNKESTVVTGVKYGLMDDHPFQEHNARIFPGKGIPCALCHMTNRTLVHVFPAENECPDEWIYEYSGYLMAGTNIPGTHICLNDPPVSYEELAEETQSHTLTIVHVSDKDGGLPKPPYEKKAAIKCVVCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGJ4</accession>
    <name>A0AAV4XGJ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein Abitram</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Actin-binding transcription modulator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ABITRAM</name>
        <name evidence="4" type="ORF">CEXT_61841</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABITRAM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000302">
        <property type="protein sequence ID" value="GIY93767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032433">
        <property type="term" value="C:filopodium tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030027">
        <property type="term" value="C:lamellipodium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051489">
        <property type="term" value="P:regulation of filopodium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039169">
        <property type="entry name" value="Abitram"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13651">
        <property type="entry name" value="PROTEIN ABITRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13651:SF0">
        <property type="entry name" value="PROTEIN ABITRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY93767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="18074" checksum="917E29A9F446A565" modified="2024-11-27" version="1">MNSSTDFLEFFRIDPSQLSVTERYFKHKIIPEYNECVLTHSNRLCLITLGPDHPILKENIDVVSVKFISDRNVDRLSNKVSGKFKKGGQRLSEKSVLCTVKCSNECEYKIYSCVSGTLVEVNENLINNPNLLKVKPWAEGYIGIILPPFPWKKHKNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIT0</accession>
    <name>A0AAV4XIT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_754271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000315">
        <property type="protein sequence ID" value="GIY93840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12399" checksum="A17EEC676EF58870" modified="2024-11-27" version="1">MLGANSYAHWGTQKWEKLSCINEYCFNLYYMDRRFVGDWGNLFWQLFTDYMVRFPVSVSIQLENVDIVLVLFSSSLVPGLHKSKTRSQRQRSTDEIRNVNRVPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ43</accession>
    <name>A0AAV4XJ43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_98641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017758">
        <property type="protein sequence ID" value="GIY94235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19769" checksum="399147B5CE83D738" modified="2024-11-27" version="1">MISKNISQSEALSSDWLMLCYFFHRSSTLGHKKHHSERRRKKEKSTPSAARRSCNFSLPGTIVRKIDQSIESRECLRFYSLREKIARLSSLPDKNIALSRPLHCVARSRFPQIESGLRVCTHEKPVSGFEFEIFRDGVFFFSTRLVGRQGILSMELLRYSSLFLMCGCFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL33</accession>
    <name>A0AAV4XL33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_282821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017908">
        <property type="protein sequence ID" value="GIY95398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10442" checksum="774462F64ADAC338" modified="2024-11-27" version="1">MHKRISGQKRVNRSEPDSEKRHQRNVRPLFGCMGTSLDCVLCHPEDLVQTLDNNDNHRKQEPQTDVMRFYPKQTLWPSFQRKEFSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM34</accession>
    <name>A0AAV4XM34_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA/RNP complex-1-interacting phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Dusp11</name>
        <name evidence="5" type="ORF">CEXT_53581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017956">
        <property type="protein sequence ID" value="GIY95743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004651">
        <property type="term" value="F:polynucleotide 5'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF9">
        <property type="entry name" value="DUAL-SPECIFICITY PHOSPHATASE 11 (RNA_RNP COMPLEX 1-INTERACTING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="102"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY95743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="21303" checksum="C2D782D01F6FA84E" modified="2024-11-27" version="1">MGRKKNIPDGWLDYYPIKDAIHEARIIPIKCPLPRSRFEGSLFDARWTPGDVMNAIPNLGLVVDITNKEPAYYDVNEFRQNGIEHVKIPCVGHHVPRDGIFYRFCEVLDTFTRQNSRNNNIVALHCTHGVNRTGYMICRYLVERLNYTARAALQIFGSQRGHPVERENYIEDLIRISESIESSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMK6</accession>
    <name>A0AAV4XMK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_747241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000487">
        <property type="protein sequence ID" value="GIY95191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11266" checksum="91003C3A4C7BE2F1" modified="2024-11-27" version="1">MDRSCNLTDVRRQMVFVARACPTVFNWRSSSIADIGRGTPEDFFHLPRDHPIMKHESQEDFLERSNAVEITIRKCVITSPQSEKHQKKKLKLRKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XN12</accession>
    <name>A0AAV4XN12_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_335451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000554">
        <property type="protein sequence ID" value="GIY95615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XN12"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14168" checksum="D603428CD3F72AEF" modified="2024-11-27" version="1">MDRRKVGRTDRQKEGRTEGRRERGTDGRKEGGKKGRNKGRKEGRSREFFTGTYTLFVRLSIYILPSYAEGIRYAMFLLVSHRDLVRITIGSGNELESVSLITPNRNENKKGMRGNAKEKFANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNS5</accession>
    <name>A0AAV4XNS5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_726431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000610">
        <property type="protein sequence ID" value="GIY96038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9634" checksum="FE91FD60D8E63D87" modified="2024-11-27" version="1">MQTKSCPFYPLGIAITYTSICTYVACISGVNITVIRLIYLSDDMLEFRTTAQVCPEPLGRTLSKKVCKLYPLRGVVIAPIHSVHCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR45</accession>
    <name>A0AAV4XR45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_363141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018168">
        <property type="protein sequence ID" value="GIY97512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12466" checksum="1C57677CB922FF21" modified="2024-11-27" version="1">MGKEFWYRWEFLAAECSLASLQKPGPAYFFHQPNALSLARIETLNIFNKSSKHRFPKKSFLKSTEMLLRFKCKFREAQISFNTRFGMSCNFCREEKMTRLFLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XS13</accession>
    <name>A0AAV4XS13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_397961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000842">
        <property type="protein sequence ID" value="GIY97841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XS13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="218" mass="24768" checksum="E1C10C1E701C2AEC" modified="2024-11-27" version="1">MSQEDGKRNRNACQIPMLLSTKEQNMGTRQGEGFNHDHMRWHETPQKGQSPLPRRDISDFFLPALFRYLRIRNSDIIRGGLIILKGCASNHVLYWLTRTCCSGLRAQGTFFHSFPPCIKPPSLTLSRGGDRQAEWRLATSRCPWQREVLAIFSPNEGGSEGRSGVRKLRRRIHRVLRVVVSLSPTPRNVNWEGKDQLFLYSLGKIGVDGRPAKMASGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZV5</accession>
    <name>A0AAV4XZV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_735861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018566">
        <property type="protein sequence ID" value="GIZ00602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11720" checksum="770AF0AB191AD6E9" modified="2024-11-27" version="1">MSGDHINRKIFCLQRSEERKEKYSAKSRKMVWHKFQAQRNNRTRIMLCRLAQLIQPKIGDRCKLDVVVPVFANFIIMKIKCSSLLPRKLEDKKKFIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZW5</accession>
    <name>A0AAV4XZW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_574391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001027">
        <property type="protein sequence ID" value="GIY99270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7513" checksum="E659F28461916AAB" modified="2024-11-27" version="1">MMAMHTSSWPGPKLSRYAAGVVMAAATPRHVKRDNFSSRPLKGEKRNLRGCLPGLEQFNHHDSRAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3S1</accession>
    <name>A0AAV4Y3S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_279031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018622">
        <property type="protein sequence ID" value="GIZ01076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13772" checksum="A5A39CFF610780F3" modified="2024-11-27" version="1">MNLNLIEIGQILMNIIEKSTSRFIQNVKFIVRKLTFIKTRRLERIKFKTDTLSAIDHKMLRKASVLTKWMRCKRSHYIPSTETRCKFGNWKMQTAGNKREFFVVRNRSKLLHEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4D9</accession>
    <name>A0AAV4Y4D9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_86001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018652">
        <property type="protein sequence ID" value="GIZ01325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4D9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12202" checksum="5D25AA2A1CD4267B" modified="2024-11-27" version="1">MAAKSAERIIKKGKARILPTTILVKILKNIICVRREELKLDRHDRVTKNRSHFEQTEFVSKVTPVLLSFCDNIIQRAFVRCSKRQLYEASYRQNSCYENLCSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y4J9</accession>
    <name>A0AAV4Y4J9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_305011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001423">
        <property type="protein sequence ID" value="GIZ02263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y4J9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="381" mass="42441" checksum="5E184327A7AE6051" modified="2024-11-27" version="1">MKSGEKEKRRVKVRRTISESCKNERDPRGKKKLRAIFISRYKNFMENEYQANRSWHYRYPSFLIPIKVYQVNCSTFQTPCMLRGPGRELPRPSVSHPVFPPVPELESQSGVRGALGWPQLLQEPWWIGDSTLVLHRRPAHQERSVRHSKMCRVHVAVHLPAFPGGGHPDVRPPRPVVPKTEEEVVRLQTLTPQHLGAAHPHPPPELPALPSPADRAPEVHAQDSSGHPRGLTPVHSLPARTGRRNLRKGLQVLILLHAPFFFRASGKFCIPLDIRKSAMCLSDLFVRKGDAPPPHSSNGTTVVSPVAIKKTLKEAASTSTRQEFCREVETVANSAAPQCRLPGGGVPARGTPLHAVRIHVPVRPARVPACPLSAFGHRCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8J7</accession>
    <name>A0AAV4Y8J7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoinositide phospholipase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_716082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001652">
        <property type="protein sequence ID" value="GIZ03796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8J7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15677" checksum="738FF90D2679168F" modified="2024-11-27" version="1">MTENEQIYRKLEKGFDLLKIYLKRKPERCTFCIKLETRQILFLKHVAGRSILESAVDLREIKEVRMGKNSKAFERWPDETRKYQNNECFHILYGNSFTLKSVSCVEEEIQFLLIIAFLFANYCYSYVVDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBH2</accession>
    <name>A0AAV4YBH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_29921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019109">
        <property type="protein sequence ID" value="GIZ04587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12035" checksum="763EEE2AB68F1AC2" modified="2024-11-27" version="1">MCRIFPRRLRFRWCTISNHRKSTAAFRQNAQAGNLQLRYYDITKQLEPSYRPNIFPCSEGSHKYSVILSGSKPAGSYWVCCTRHALSHHHHARVTYSACVIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDT7</accession>
    <name>A0AAV4MDT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">General transcription factor 3C polypeptide 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GTF3C3_1</name>
        <name evidence="1" type="ORF">CEXT_60851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002152">
        <property type="protein sequence ID" value="GIX70569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10631" checksum="43BF3A0A697BFA55" modified="2024-11-27" version="1">MFMKLPRYAKDLEFQALLGCYFNGSHKYTYLFIRELVSKNLNKKKNKAWNLYSLIASCSPENRQNRFCMRLMLKDKDHLDNLHFIFIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEZ4</accession>
    <name>A0AAV4MEZ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TSPAN7</name>
        <name evidence="8" type="ORF">CEXT_88421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019688">
        <property type="protein sequence ID" value="GIX70596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1450.10:FF:000029">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000301">
        <property type="entry name" value="Tetraspanin_animals"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF252">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002419">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002419-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX70596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="242" mass="27199" checksum="880FED7F64F98615" modified="2024-11-27" version="1">MRRFQTVAALTCMKLLLLIFNVLFWVAGIILLVFGLWMKISLHYLFELSDQYNEVIPYIFIGTGSLILIVSFFACCCTVKGQPVLLYMLAVFLGLVFICELTAGISGYVYRDNIRDGFKSGLNNSISLYGDGRIRDRDIDMVQKYLKCCGVQDYLDWYSKWGNHSVPISCCQDRTSCHYSPVEDTAEIYTVGCYVKVVDFVDQNLGSLLAGALALGSFQLFGVMLACCLAKYADKAKYEPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHC8</accession>
    <name>A0AAV4MHC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_190531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019753">
        <property type="protein sequence ID" value="GIX71421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7777" checksum="94D092EC566D90B6" modified="2024-11-27" version="1">MMPRGEEFFDPPNAAVNQEKRNGRDAGAEKSLSPAQLPSSAACLLSRPPDVSENSLNVILLQYDGMLANATAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHI9</accession>
    <name>A0AAV4MHI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_725681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019786">
        <property type="protein sequence ID" value="GIX71755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11995" checksum="25335A2E092A011B" modified="2024-11-27" version="1">MQPISRATPDLNANNRQVNPVENLKRHLRKREETNIPEIPDYREHHCSFAGHRSFVLIAAFFLLFLVTQKGKWLEIMEHMITHKVDIRNGIGGNNECQGGYTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHX2</accession>
    <name>A0AAV4MHX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_90561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019819">
        <property type="protein sequence ID" value="GIX72099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18882" checksum="7BAFF7C487C3C234" modified="2024-11-27" version="1">MSSTIIPRDGIIYRVFEPENSSIVFNEMKRHNVSENFYQKDNEIEDIRHPLMNTKLINNSVSKKQKIKDSRKSSDTPNSTKKIFEIFIHYLNNSNSYKSREIFRQNSNESKDTSKTLMNTNREKQLYHTTKYPEEIPERRISTQKLDRNGYPPLFQTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIB3</accession>
    <name>A0AAV4MIB3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_352811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002216">
        <property type="protein sequence ID" value="GIX71367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIB3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12305" checksum="57CC7A4BC61EFF84" modified="2024-11-27" version="1">MNRSGEEGEKDNAVQCSTSTKKRTSSFVGQMAQEIVHRMRTASFASQVAQDGFITSIQQDQCEESSSQIVEFSGTLCQKWNQLCQRLQKLRKQAATTTVESSYCQPMAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIW9</accession>
    <name>A0AAV4MIW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_239991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019851">
        <property type="protein sequence ID" value="GIX72489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13845" checksum="E2130955E4FBD12F" modified="2024-11-27" version="1">MLCKHSGRKAHSLLLKLSNHSQAKPYYRLPLGTAGVFQHSIAAQCTMSWHSFHSKRRETAKRRISASITAILIPFSKFSSGISEGESAIRKLSRPYTYVYNGKKMSRAFCLTYLVNSSDEIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJ69</accession>
    <name>A0AAV4MJ69_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 2J6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Cyp2j6_2</name>
        <name evidence="8" type="ORF">CEXT_22021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019813">
        <property type="protein sequence ID" value="GIX72019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJ69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004508">
        <property type="term" value="F:steroid 17-alpha-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042446">
        <property type="term" value="P:hormone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042448">
        <property type="term" value="P:progesterone metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24289">
        <property type="entry name" value="STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24289:SF1">
        <property type="entry name" value="STEROID 17-ALPHA-HYDROXYLASE_17,20 LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX72019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13506" checksum="EA81B9F8B3246FF3" modified="2024-11-27" version="1" fragment="single">MSLFDLRYHTIAENCNLLNVVLGSLVVLITLYLWKSKRKYKLPPGPRGLPVVGYIPFLDKYPFETLTKLGKKYGNIYSINFGGSYHVILNDFEAMKEAFNNPAVLDRPLHAFDSLPGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJD6</accession>
    <name>A0AAV4MJD6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_209061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019845">
        <property type="protein sequence ID" value="GIX72415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11793" checksum="44940A5D0DE9D2F5" modified="2024-11-27" version="1">MHFYPCIHFGKLISKHSSSLPDFIDDLVFFWFRSERRAFADPHRAKFWREQDRASLSPELLLGRPPTTAPILTTAPRGTPRPSLAKLPTSTARYANLVTGQLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MK59</accession>
    <name>A0AAV4MK59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_560241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019829">
        <property type="protein sequence ID" value="GIX72225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MK59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10101" checksum="B308C3229208209A" modified="2024-11-27" version="1">MKKITPVQQLLATGCYILLTPGLAEKLCRSLSKSYRSRSSVANRYRSHPCVFTANSGIGGIDSGEDKMMTGWPKNTLNSAPAPPDKCAVNHVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MN23</accession>
    <name>A0AAV4MN23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">E3 ubiquitin-protein ligase UBR4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">UBR4_2</name>
        <name evidence="2" type="ORF">CEXT_700071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002441">
        <property type="protein sequence ID" value="GIX73750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MN23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045841">
        <property type="entry name" value="E3_UBR4_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19423">
        <property type="entry name" value="E3_UBR4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E3 ubiquitin-protein ligase UBR4 N-terminal" evidence="1">
        <location>
            <begin position="24"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9293" checksum="7CBFB1D88CF7FCD9" modified="2024-11-27" version="1">MASSGCSKVSSFTSAIADYLPPFTWCPENNSSKEMIRVMLPLLLDATTESLGDYTTLALERLIGSPEGDDYLSFNYFEVLTQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MTU9</accession>
    <name>A0AAV4MTU9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Ras-related protein Rab-36</fullName>
            <ecNumber evidence="3">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">Rab34</name>
        <name evidence="19" type="ORF">CEXT_1421</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="17">The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Golgi apparatus membrane</location>
            <topology evidence="15">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01002533">
        <property type="protein sequence ID" value="GIX74862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MTU9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000707">
        <property type="entry name" value="RAB36, member RAS oncogene family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00058763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00067830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="GIX74862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="236" mass="26677" checksum="7A10D625233B339C" modified="2024-11-27" version="1">MDRIYQSDISQDVGNSPYSTIPLSKTLEERTLRDYPLPYDSNCSPNKETHFSYQIRTACSKINSTKCDALRLSKVIVVGDVAVGKTCLVRRFCVQAFDTNYKATIGVDFEAEKFYILDVPYILQIWDTAGQEKFKCIASSYYRGARVVILVFDFSIISSLYNISKWLDDTLKCADNPLLFLVGTKKDMVSNSVYKLTEKEAMKLANAIGAEYCPVSSKTGENVERLFKTNCSFNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MU18</accession>
    <name>A0AAV4MU18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020209">
        <property type="protein sequence ID" value="GIX75917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MU18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9393" checksum="C1ECCB66F621BFA0" modified="2024-11-27" version="1">MSASGVRGHSERHWISGGGIEVAPIINYSTTNSFAAAIVAAAPPKGKEGFVLAGFSVSGICCHPVLNICIDFDTFLFSYALPSYLTLVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUJ3</accession>
    <name>A0AAV4MUJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_249451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020222">
        <property type="protein sequence ID" value="GIX76063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8704" checksum="BB096DCE0C1598D8" modified="2024-11-27" version="1">MCTPTTGLQLCKCRHSGLIQIPSEPTFLSFAAHSASRTGTGKLSFQSEPFSQGCPLSICIRSKGSTASNQRLTHWNGTSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N5U6</accession>
    <name>A0AAV4N5U6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_413021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002997">
        <property type="protein sequence ID" value="GIX80087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N5U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9529" checksum="087AD9006965E7A8" modified="2024-11-27" version="1">MNCRIRHEKALVTVKTGRTHAVSRAIGSPDIGNWFHGGAINSNHHLGGRGFLRIPTFLTPVDEMEHLVIPLSGIGLRAIWFGGSIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7R3</accession>
    <name>A0AAV4N7R3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_198141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003061">
        <property type="protein sequence ID" value="GIX80784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX80784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15586" checksum="BA2D7D31603CED30" modified="2024-11-27" version="1">MQRSRGKKIDFIMIEIGRVRLSFYPVLLLYTVIILFFRRFSPVGLATFSPRLLSMYFDRPHCQTPGHETNSTDATLSPVPPKRHSGLFFLPLVSPQDNIKRKEKPTAEPILLLCPGDKQKDRGGDGMQLTSFLEGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8A3</accession>
    <name>A0AAV4N8A3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_70756_1</name>
        <name evidence="6" type="ORF">CEXT_532191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003046">
        <property type="protein sequence ID" value="GIX80565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050751">
        <property type="entry name" value="ECM_structural_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24034">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24034:SF46">
        <property type="entry name" value="LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX80565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16000" checksum="65B1805D82D7AA37" modified="2024-11-27" version="1">MLFSEADPCLKDIKHLNCGPETECKRIEGKGFNYKCTCSPGFESYKAYHPLADKTTVIHYCQDVNECLDQKACPNRTRCLNTYGGHDCICSDGFRPSMDKSVPPKIDCVEICDPKLCRHGKCEVIGDTVGCRCDDGYMGLIANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFK0</accession>
    <name>A0AAV4NFK0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_413781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003215">
        <property type="protein sequence ID" value="GIX82214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13226" checksum="3F042EB63889BDD4" modified="2024-11-27" version="1">MECVNLLGQGRPVSQIQLATSRVAVSFLSNMECVNLLGQGRPVSQIQLATALVAVSFLSNMECVNLLGQGRPVSQIQLATARVAVSFLSNMECVNLLGQCRPDSQIPTGYSPGGCLLPIKYGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NH18</accession>
    <name>A0AAV4NH18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_175411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003293">
        <property type="protein sequence ID" value="GIX83105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NH18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="62" mass="7081" checksum="897906C698B708EF" modified="2024-11-27" version="1" fragment="single">PHLSEVQPPTSEERYSSGHLLRTQPEGETGAKGYLIYCYFGRCYRFFFGFSFFQLPRVPGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK83</accession>
    <name>A0AAV4NK83_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_353951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003461">
        <property type="protein sequence ID" value="GIX84893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="18644" checksum="00A2E9E54ACB6E2C" modified="2024-11-27" version="1">MHHVPGKQIGNRNFRIENARLLHENDENISFEVMSIASYTLFPSVRQSADATQIFEANQSSSHFPRREALLSECVPHLCKYVVIGRSHVWGLSALSPRCDYSPDMTRVSHDALFQFRFEMHHPIPRDAVPITLPFSLDQSERRNAATHNCCKRAGLRYRLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLZ6</accession>
    <name>A0AAV4NLZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_703381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003512">
        <property type="protein sequence ID" value="GIX85399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="395" mass="45391" checksum="1885F2B42D43619B" modified="2024-11-27" version="1">MEKNFDKSHTSKKIGKSVFGGLVHEKNEYSLISQTLTNVQAIKLDPPSDRVVQPCPYCKDIDCHRWLAIREVSALIARDGAIYFRATDVARLLGYKDGYHFTKTVPIHKIRVADLVMREKMAYKNTWMLPYTEVIASMTSRKCMRRNFALAHRLHHVLTEGRGKWEFNRLLFKTSPCKAPKLLIQDSGEWVPQLLSVFRQKVMRYFYKVQYEGGQDEVVQLDDDDDDDDIIYKCDSVMPPTPYVKGECMDDTVDDPPSSQEPSGQEMAANDEPDQDYEDFDIDLSTPLVIVEDDLQVHTEQATLSTLAQNHKETIPSTETREKCTIPSTETREKYTVPSTATQKHEEKMTIDFAFAKVPDIIVLANKMGTYEYKMYKFAKKDGSVTCYRGDEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCZ1</accession>
    <name>A0AAV4PCZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baculoviral IAP repeat-containing protein 7-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">birc7-a_2</name>
        <name evidence="1" type="ORF">CEXT_357101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004360">
        <property type="protein sequence ID" value="GIX94313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00022">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050784">
        <property type="entry name" value="IAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10044:SF139">
        <property type="entry name" value="DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10044">
        <property type="entry name" value="INHIBITOR OF APOPTOSIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="26058" checksum="3748D3E810C93794" modified="2024-11-27" version="1">MLSNVGNIPMQKQKTCEKKSLSKLIPNTKSNNTSLSGQAKYPMMMELNNRLATYKDWPLIMLPQTAFSECGLFYTDNEDIVTCFYCGGSLGNWELNDDPWVEHEKYFPDCRYLNLVKCHRNPEQHSTHHNLEEKKKKVVTHHLNITGGHFISFHHLCEAILDYKDREPANMWGPRIKGKSSLVIHLLNSMTTGVSMVDDNHCNRQLVLTNNVYGSSLPGFKPSCRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PN71</accession>
    <name>A0AAV4PN71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_448821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004795">
        <property type="protein sequence ID" value="GIX97578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PN71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10832" checksum="612FC3CE034DB3E0" modified="2024-11-27" version="1">MGCDIASAHLPGASFMAYKWRCSVFISGSKPHRKRIFCCISSDGIVFALGVVKKKVWLFGWCPNVECGTAERFYNLSEYYVRRREVSNALWVLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNM9</accession>
    <name>A0AAV4PNM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_214551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004815">
        <property type="protein sequence ID" value="GIX97746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX97746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9395" checksum="457689918F9264C7" modified="2024-11-27" version="1">MAPLRIPPKAPFGFERRILIVLAWKDIRKEERKKKNKTWGLERTIRNWIHAELSLEQVVLCCMGLVKEDPKYVGISFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV02</accession>
    <name>A0AAV4PV02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_471801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005128">
        <property type="protein sequence ID" value="GIY00009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14616" checksum="D269E3B8FDED1F58" modified="2024-11-27" version="1">MYFYISPPKESYHPSKHSVPKCTGLVPDKRPRLLNFSANGALFKTRHVRPDWKLLYQYGDKLDKFVGWNVPSLGLKKIPGKCDPDSVLEIILLNVRLEAAPLFPPSLRHTTTTTTNVRLVAQRQRKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAB0</accession>
    <name>A0AAV4QAB0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_44341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005822">
        <property type="protein sequence ID" value="GIY05262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9189" checksum="321A2D031DA14AFB" modified="2024-11-27" version="1" fragment="single">IPKVTTCQGISTHKQVQKYRDFPCEKVKYGISNIVTQVFSGDSWSGTGDPRNPMFCTPYLVSNSPRIAGFHYPNSLTILLPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBH2</accession>
    <name>A0AAV4QBH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeodomain-interacting protein kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HIPK2</name>
        <name evidence="9" type="ORF">CEXT_539741</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005948">
        <property type="protein sequence ID" value="GIY06331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF17">
        <property type="entry name" value="HOMEODOMAIN INTERACTING PROTEIN KINASE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY06331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="248" mass="28542" checksum="E5914A95C2780072" modified="2024-11-27" version="1" fragment="single">RGDYQLVQHEVLALSATNQYEVLEFLGRGTFGQVVKCWKKGTNEIVAIKILKNHPSYAWQGQIEVGILHMLSQENADEFNFLLLKLKQLGLIHADLKPENIMLVDPSSRNYFLGLPFCEAIDMWSLGCVIAELFWVGQPLYPGSSEFDQIRYISQTQGLPPEHIHQRSMKQRQILSQKEARKYIFNCLDDMAQVNVPSDLEGSELLAEKLDRREFIDLLKRMLTLDQERRITPGEALNHSFCNIKSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QF98</accession>
    <name>A0AAV4QF98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_269341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005997">
        <property type="protein sequence ID" value="GIY06761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QF98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9828" checksum="DDE73E201B60B9B4" modified="2024-11-27" version="1">MQCSQEIFISRYDILERGADLLWSDFRGPHGEALIYPKLLRPCHCRRNGNSANPFMVQGDSTTFLPNATNTATHVACSTGRNHFLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFQ5</accession>
    <name>A0AAV4QFQ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006266">
        <property type="protein sequence ID" value="GIY08548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFQ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11398" checksum="B3029575E5B28858" modified="2024-11-27" version="1">MRLHEDQLFVTSESRIRPGRAYYPSNSRQGDRVKGVGKNAARWNFENNCRRNSMGKTAAMFPRITLNHFMCRVGTNYQMELCQGIGILSSWFLSKLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QNF8</accession>
    <name>A0AAV4QNF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_640271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006558">
        <property type="protein sequence ID" value="GIY10735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QNF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20253" checksum="A5C3FF6E67A034A3" modified="2024-11-27" version="1">MRFINTGMTNTYCRIRLTIRNFVRTPIEIVLRKFALFPTFSMTFWSMNAHILCAFSGIPIDMGTFDWNRVEIAPRSLRKSKSRIGRWGNGRRGGRSSGSSRGPGEWSEEGANGGPRKRSQGRRHHQAQEPPAIPLHAPPPTWSKIERKTTVIYDDNVTVHYMKKYSDIVCFDVYMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QW44</accession>
    <name>A0AAV4QW44_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_384851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006773">
        <property type="protein sequence ID" value="GIY12317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QW44"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16157" checksum="6DE98DEC82EBC22E" modified="2024-11-27" version="1">MQTCRIRIPVMTRTIRMFEFSGDIRCNHCCLNLMANGIAYFKRFRAPDGGVLDGKFVITTRYKFSELCDYPFSASERPSGICVVKSDYASLATVNCPVSSAHGYLLSTSAFGANVVGTRCKMRASSSCFAHHLKLEYIPGNDRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QY62</accession>
    <name>A0AAV4QY62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_732971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007051">
        <property type="protein sequence ID" value="GIY14200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QY62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="16956" checksum="17E8B98478E3B04B" modified="2024-11-27" version="1">MSKNTEQIESDTGPTCCARCNHAHKNVALKLTYINATHVHPCTRFPGPTPVGSKREEPLTFKEQCDSHLRKRIWTQCTNTLDSLSNPVLLYYLYTSVIPRQSKCNLLYLEVCEPGAEAPVDAVKLRSLFTQMRPKDPMKKMTSQAMSVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R781</accession>
    <name>A0AAV4R781_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_519651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007497">
        <property type="protein sequence ID" value="GIY17320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R781"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10439" checksum="23A7BAF0CC8FBF3D" modified="2024-11-27" version="1">MKETRKVSQVQISSVASHGFPNDSAAPFKGSSSSAPPCLHPPFPAGSEERVDPSRKMKRSSFSSFSLARVFLHLHLHSGLPLKVVCCSHFAASWFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9J7</accession>
    <name>A0AAV4R9J7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_801811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007446">
        <property type="protein sequence ID" value="GIY16991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9J7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="9950" checksum="AD4615992BC06BA7" modified="2024-11-27" version="1">MNNVPPSAVGNSFTDCSCECLQSRNAVQNLQFSSDDQINEEPEAHRRADPCTLPERNGFSPLKSEDGLNNPQIIIEAPGNTMTGTAAATITVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAS4</accession>
    <name>A0AAV4RAS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_598481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007575">
        <property type="protein sequence ID" value="GIY18106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="271" mass="30933" checksum="4BC4053A8220FAAA" modified="2024-11-27" version="1">MGYFNTLKVWDNNKASREEDHTLIMRYFNTFQITSKRFAVTGNNPPITEPLQAWTFRGTGSKSETQVTRKEKRIHLGNKGPKINGNKISKNGNNIITSKRFAVTGNNPPLLQSHYRDGLLGVKDTGCGYLVVGPYVSGFSMIRWSAGSKSETESRENRSVSTWEKERPKMETGNKIIPDQNLKPSHEETEAIPPGKERPQDQWEQNNPFLSLDYVQAFCSYRKQPTLLQSHYRDGLLGGIRYGKWLLGYRPIPKRILNDSQEDSATEETFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RKC8</accession>
    <name>A0AAV4RKC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_367951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008005">
        <property type="protein sequence ID" value="GIY21346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RKC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7742" checksum="4040A2B712053532" modified="2024-11-27" version="1">MVSGGRQALVFLLKSIEKSDGIWRKASLGIPPQVHRKIVQAYGYIVTIPVDIVANQRLPKEACYSIDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUZ4</accession>
    <name>A0AAV4RUZ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_51151</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008333">
        <property type="protein sequence ID" value="GIY23952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045197">
        <property type="term" value="P:establishment or maintenance of epithelial cell apical/basal polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007157">
        <property type="term" value="P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000255">
        <property type="entry name" value="Sushi, nidogen and EGF-like domains 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051022">
        <property type="entry name" value="Notch_Cell-Fate_Det"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049">
        <property type="entry name" value="CRUMBS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049:SF22">
        <property type="entry name" value="DROSOPHILA CRUMBS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="38"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY23952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13295" checksum="EB901D165696E1B3" modified="2024-11-27" version="1">MRNRSLYTKPLSPRWQMQSGGENYNCECKEPYSGGNCDSSPCVSHPCQNNGKCVIDEHGYKCECTSPFKGIFCENGPCSSNPCQHAGVCKVQGQTFKCECRQPYSGKKLRIGSMYTKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVJ3</accession>
    <name>A0AAV4RVJ3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_142891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008440">
        <property type="protein sequence ID" value="GIY24699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9986" checksum="6A9A9CD08E27BEF3" modified="2024-11-27" version="1">MVGWYDLRSLHLVACSTVAALRSLHSVAYSIVITLMNVCRLVVNDDKSVSHRQLNRMSQYTCRCMAITLENFLKLLTQAWATCREHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVU1</accession>
    <name>A0AAV4RVU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_78321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008468">
        <property type="protein sequence ID" value="GIY24936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13084" checksum="D450091AF171A4A4" modified="2024-11-27" version="1">MSKVELITVLVKENIRRIVSSKIDNSPGFLFHVFSKPATAKKLRFNFGIAFRPLMQIDAYQRELSNIDGRGNLATWIDFVSPTPCFFLPVHYNHAVRESLASQKSAFYAGVSGSSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RX67</accession>
    <name>A0AAV4RX67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_239450_1</name>
        <name evidence="3" type="ORF">CEXT_351841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008471">
        <property type="protein sequence ID" value="GIY24971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RX67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35555">
        <property type="entry name" value="ENDONUCLEASE-REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35555:SF3">
        <property type="entry name" value="ENDONUCLEASE-REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY24971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="386" mass="44339" checksum="3403E4B3E47FA6B6" modified="2024-11-27" version="1">MDDINTDEVENAVPLAMGSNSPKSRSVSVTSRFYEAESDDQSVKSFIENTSANVKPKNEKSRVKQSKHLPYWAWYLIAKSHVWHSLVSFIFMSICRTHTIGLRRFIKEIEYDASLIQRHLSFSSHIVPLNQDDIWQETTWIAEDEEEEGYVSYRTKTGQAMSVSKKNNLRMRASSPNIRNVDPQGEISVLFSPITNNMDYIDDQSSVSDFEWNYVQEDKSFIPVRKVIKCNKNVPEDSSATPHTMTNRELLHHFWKLNCRLQFSSCALQRWYASFVSLVLLRCSTYLVRWLGHPATISDILQFSLPLIMLVVLSVCLAEVNFESGRVLQSIYPTEERINPIKYMNLNSLQMSVYGFALTHGTIVTVVFAMLVAFVSKIVLTEMMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9M6</accession>
    <name>A0AAV4S9M6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">coq6</name>
        <name evidence="14" type="ORF">CEXT_257421</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009024">
        <property type="protein sequence ID" value="GIY29105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9M6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000086">
        <property type="entry name" value="Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="14" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="FAD-binding" evidence="13">
        <location>
            <begin position="199"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY29105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="445" mass="49704" checksum="1890263550EEA799" modified="2024-11-27" version="1">MNVFRTLKSFPIKSNIHSRRYLNVRSENVEKLSKTTWDIVISGGGMVGCALAASIGSSPILSKKKVLLLETSPKTEYQIDANKYSNRVCALNNSTKQLFEGFQAWDKIYSIRMKEIWESCSDARISFQHDSMQDEVAYIVENDVILNSLWNRINGLSDNIHVLKGMKATDYILPSNQMDLVTVKLHNDIPLKTKIIGKIIGADGVNSLVRNKMNIKYIAWNYDQKGIVATLKLSEPTENIVAWQRFLPTGPVALLPLTDDLCSLVWTVSLPMCEKLLQMQEDQFVDSLNSALWDEEKKNSSVESAIKSLKNAISNLTSDYESVRQIPPSVLSIEPKSRASFPLGLGHATEYVAPRVALIGDSAHRVHPLAGQGVNLGFGDVKCLTECLEKAVYDGECIGNLQYLLEIHTFCINEELGSHCIRCLQAYKKYNDRPSISVSPESTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBI7</accession>
    <name>A0AAV4SBI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein O-glucosyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Poglut1</name>
        <name evidence="8" type="ORF">CEXT_495081</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Protein O-glucosyltransferase. Catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue found in the consensus sequence C-X-S-X-[PA]-C in epidermal growth factor-like repeats. Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009427">
        <property type="protein sequence ID" value="GIY31853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035251">
        <property type="term" value="F:UDP-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035252">
        <property type="term" value="F:UDP-xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045747">
        <property type="term" value="P:positive regulation of Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="7">
        <location>
            <begin position="4"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY31853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10670" checksum="BC2C4F848BBE0E4A" modified="2024-11-27" version="1">MFPFRCSGVEHFILKLIDKLPDMEFILNTRDWPQVNKYGKPLPVFSFSKTPQFWDMMYPAWTFWEGGPAISLYPTGIGRWDILKKILIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE10</accession>
    <name>A0AAV4SE10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_491571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009434">
        <property type="protein sequence ID" value="GIY31915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8394" checksum="7BF5959511361011" modified="2024-11-27" version="1">MEIKEQSKGLNPSMTFDIESEMKEKNLYFYEISILTLGKKWKVKPRQRNQMYNDFRLRNLFISSPFVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFE2</accession>
    <name>A0AAV4SFE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Steroidogenic acute regulatory protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">STAR_1</name>
        <name evidence="2" type="ORF">CEXT_263861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009513">
        <property type="protein sequence ID" value="GIY32455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140284">
        <property type="term" value="C:endoplasmic reticulum-endosome membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099044">
        <property type="term" value="P:vesicle tethering to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000799">
        <property type="entry name" value="StAR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051869">
        <property type="entry name" value="STARD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46121">
        <property type="entry name" value="STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46121:SF4">
        <property type="entry name" value="STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00978">
        <property type="entry name" value="STARPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11145" checksum="7CDF9482F012B62B" modified="2024-11-27" version="1" fragment="single">FVNVRIWKKQDSGYVQGSVSIIHPDVPDITKYVRGEQGPTVCIMNPSNDNTDSCKFQWLLNTNLKGWIPQYLIDQTLSSVMMDYVNSFRKFAAPKTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SLN6</accession>
    <name>A0AAV4SLN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extended synaptotagmin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ESYT2</name>
        <name evidence="2" type="ORF">CEXT_718151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009632">
        <property type="protein sequence ID" value="GIY33380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SLN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008429">
        <property type="term" value="F:phosphatidylethanolamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051634">
        <property type="entry name" value="Extended_Synaptotagmin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45761">
        <property type="entry name" value="EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45761:SF1">
        <property type="entry name" value="EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9751" checksum="9DC4A3455F3B5701" modified="2024-11-27" version="1">MTPDRNKETKQKTQVAKNTCNPIFDESLEFDVNMSEVANYSLEVTVISKSGSMMFPRGKILGKTVIDLSLQDLSKAATEWYDLDATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQV9</accession>
    <name>A0AAV4SQV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_794151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009969">
        <property type="protein sequence ID" value="GIY35842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11411" checksum="6117C5A46C1B7427" modified="2024-11-27" version="1">MQSNAESRLPINPAQSAARLRKRREKVLFKMVRFFSERVIDCALCKSRYLESSLTCGIPGEMQSNAGSRLPINPARSAARLRKRAGKSLIQAGPAFLFRESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SU16</accession>
    <name>A0AAV4SU16_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquinol-cytochrome c chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_652611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009979">
        <property type="protein sequence ID" value="GIY35927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SU16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="2">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY35927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="17044" checksum="369C794913E4B1C6" modified="2024-11-27" version="1">MLDAVLGGCAATFIRWMRKYRNHPYHIIEKRNKNNKIFRDIKNDNSKFQHVKYFSTSLNFRSSRFISWIKIKLYNLISSSAKTRLGASLTYEKCGDKLNYNEFFKYFDLPDTFNSWFLTIQLHIWMCTVVTVSEKMEVPFATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SU47</accession>
    <name>A0AAV4SU47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_740321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009859">
        <property type="protein sequence ID" value="GIY35118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SU47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10048" checksum="1D3D59B33916C959" modified="2024-11-27" version="1">MGENALGRSMFILPKTRDVCKYKERLPSCIKDDDGEGRFEIGLGFLGSRGKKIELEKYQEVEEFRRNFTGRSFCTMQFFLHISSTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWW0</accession>
    <name>A0AAV4SWW0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="21">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">MAN1B1</name>
        <name evidence="23" type="ORF">CEXT_500011</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="17">Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 21">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="21"/>
    <dbReference type="EMBL" id="BPLR01010303">
        <property type="protein sequence ID" value="GIY38434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000010">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 20" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 21" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 22" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="595"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="20">
        <location>
            <begin position="435"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00053655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="GIY38434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="605" mass="69541" checksum="8C597588CCED2854" modified="2024-11-27" version="1">MMNYNKQLNIDSDIEKGLLDKEKSDIYLFSRDDGFSHPHSRSIRRLWNQLSRLQRFIIVVLFLFVILCVIVLLPWTDSSFLLGIKADMPKAQNSKQKNLVIGLELDEKVKNRIFNTGSINVEKNNVPKLQMEKVSFDGVRSNLMEKIVGAALEQKEKQKAIVDAFLHAWKGYRSYAWGHDHLKPITKTFQNWFGLGLTIVDSLDTMYIMGLEEEFTEAKEWIKEKLNFNVNKDVNFFETTIRVLGGLLSAFHLSKDSVFLEKAVDLANRLMPGFRSSSGMPYSDVNLQTGHAHPPTWGQDSTVSEISTVQLEFRDVSRLTGDPKFEAAAFKVSEHLHKLPKRDGLVPMFINAESGQFRSTSTITVGARADSYYEYLLKQWIQTGRTIDWLKEDYMQAVDGILKHLVKQSLPNKLTFVGELLSGRSYSPKMDHLVCYLPGTLALGFHYGMPSSHLKLAFDLMDTCYNMYAQTATRLSPEIAYFNLQPHGTSDIIIKSNDAHNLLRPETVESLWYLYHLTRNETYRDWGWEIFQAFEKYAKVQDGGYTSIGDVRNPLITKPRDLMESFFLAETLKYLFLLFSDNQELYSLDKYIFNSEAHLLPILKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY33</accession>
    <name>A0AAV4SY33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein 423</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Znf423_3</name>
        <name evidence="8" type="ORF">CEXT_480541</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010241">
        <property type="protein sequence ID" value="GIY37944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="468"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY37944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="593" mass="64689" checksum="A369EB87A8515389" modified="2024-11-27" version="1">MSGKKEGFLDNSTYVHRVGENSHQATGRCEDAYPRCEDLIQHPQRPDAVPVRLLPASVQAQAQPRPPRQTAHGRPEVSVYPVRVRLLAQRPPQDPHEDTRQWKPYQCTVCNRGCHNTAAALSSHMQNHKKITEPPTDLPVAPYTRGSTPNDHQGDKDSREEDSPDPPKPLLCNFCPQVCSSPNALGDHMLQSHRSFSSSSPLSDSPRPPSSRGMLQVPRRTGIPQCYLSPQKGPRRDFPSMKLTCGFCSKSDFPTFESLQLHVQVLHVPTGTTADSALAASLRSLQSMLHSKRPHHGQNAIMDNFIGFSGMECDSSLTALHILQKHAAMNENLMLKRPNDIYCSQCNIGFTSSTALLDHVRLVHETTLLQSPLPFVPHQQPLQSYASSRLRPNGAKHLKTSNALGSHSAVFNGTASSHYRRQDPGGGQNIPTGQYGEKNSIILIVLEYYTRGVVVMGITSPETTPNTLLCSQCNAGFSDFESFRTHLKSHLDAAAAASTSGQGPASGAAASLQLHTCPECSAEFSSESPAGQPRDRSLPVGLHGVRVPVLHEALPETRRTAEASHGCPRLPSVPVCPLQADLRLQGQSHFNVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2Y9</accession>
    <name>A0AAV4T2Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_540081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010688">
        <property type="protein sequence ID" value="GIY41033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="197" mass="22374" checksum="3E34876E007A2F20" modified="2024-11-27" version="1">MFCLPLLCVDNETCLKWQHPGPLKKKHCSISSWRRFFDLCSVPPAGALPSLAHFTGFPLIATSSQEDALKNWLERLQICNCTESQLGKGGQFVAMQFGKGERRFLKSCQWLPRTGVREGVVQTIVRAAARTKKSNGIKERQWRNYGGGKNTAALSVRRLMNITERRLSRCQIVNTPLHWLLCSFSQHRIRCSRAQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBQ1</accession>
    <name>A0AAV4TBQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_757511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010893">
        <property type="protein sequence ID" value="GIY42776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10893" checksum="7F8FAE7AC5A44967" modified="2024-11-27" version="1">MDLSCPMHDKSIDIETIKVMVYNKTMLKQQILLILRLEGHNSLEIMADNKFACSRLVIYAHATNSLVEGDRMGHWFSVNTWPWFQIGLKDRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U0I0</accession>
    <name>A0AAV4U0I0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_813511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012086">
        <property type="protein sequence ID" value="GIY51276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U0I0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8055" checksum="92A295543894496E" modified="2024-11-27" version="1">MRLLSISHRGGFPFEMGRLPLQGMNRRGTQKTNEGLLKTMPALLRTMYHLASTSVRFARQLQTVKDSKCSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U881</accession>
    <name>A0AAV4U881_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PIN-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SLC9B2_2</name>
        <name evidence="3" type="ORF">CEXT_420551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012414">
        <property type="protein sequence ID" value="GIY53835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U881"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051843">
        <property type="entry name" value="CPA1_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31102">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31102:SF1">
        <property type="entry name" value="CATION_H+ EXCHANGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY53835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="13795" checksum="AD858758DB8C7D28" modified="2024-11-27" version="1" fragment="single">AAIGSQALNYARQHKLDKDLIQHGTTVLNVSVLSIMLTAPLGAVLIGMLGPVMLEQDVIPSDIDETYEVDDAFEDRVEEEVSAATLVTPIGGPKQHLEPSSSLVSGNWPFLMHCTGTSFLKTAANHSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8M9</accession>
    <name>A0AAV4U8M9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_742681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012474">
        <property type="protein sequence ID" value="GIY54130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14794" checksum="EA85CDF9927406D2" modified="2024-11-27" version="1">MKNQFEKNLKKKSDKKSQKKRQKILENVPDPVGSIYNRVYNHFFGGEFSRTTSSSCRAKARFCCFGWMPWTKKTFLTRVPPAEEEFQVSVEDFQMSVKEEKKTVLENVSNPVGSVFNRVYNHFLGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UB43</accession>
    <name>A0AAV4UB43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_596741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012562">
        <property type="protein sequence ID" value="GIY54889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UB43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY54889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12585" checksum="DF6E764B79169B86" modified="2024-11-27" version="1">MLFESFNEKLLIGLDEEGFDIGDSTKYERGERESLSSFIMTNFDTFGERESRRVILDAKFFQGCQIKGLSVGREKQNYKDKQLKGKLWVFLGEINIQIFCFFCLFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UBG8</accession>
    <name>A0AAV4UBG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_372911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012612">
        <property type="protein sequence ID" value="GIY55139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UBG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11383" checksum="05F342F5D2D183B7" modified="2024-11-27" version="1">MQEVGGRGRERRRRKKKKIPSCFLASSSSRKTEVIGKKVWQWKEIRALAENEALTTGKENKAHREKVMIFFPLFTSAPPLYVHFTPRCQLAKKGDRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UH11</accession>
    <name>A0AAV4UH11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Equilibrative nucleoside transporter 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">slc29a4</name>
        <name evidence="8" type="ORF">CEXT_69991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012854">
        <property type="protein sequence ID" value="GIY57053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UH11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008504">
        <property type="term" value="F:monoamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF10">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY57053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14223" checksum="3DC5E6F50EAC9D0A" modified="2024-11-27" version="1">MPVILMAIFNFFDFIGKILASVSHDWTHRQLLLLSASRIFLVPLLALCAAPRGSPFLSGEGWSMVFSMVLGLTNGIAGSVPMIVAPSVVPDERKELTGNIMTLSYMLGLTTGSGVAYLIDYFLGPPLLHPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UIF0</accession>
    <name>A0AAV4UIF0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DAZ-associated protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_245944_1</name>
        <name evidence="2" type="ORF">CEXT_68671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012919">
        <property type="protein sequence ID" value="GIY57522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UIF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY57522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12197" checksum="58B1CBCD4659E07E" modified="2024-11-27" version="1">MTTNSRQSAPAKGDLSPPHVAPYQPRATVMQPYTSDQTPYGSMAKPLWSTSNAFQAAAAPASYWAPSQPMFNHMPYSSPAASQHSNYFSNAPIPQPTVPRFPIKDMFQDCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMF1</accession>
    <name>A0AAV4UMF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein mab-21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mab-21</name>
        <name evidence="4" type="ORF">CEXT_410331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the mab-21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013125">
        <property type="protein sequence ID" value="GIY58917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.40:FF:000002">
        <property type="entry name" value="protein mab-21-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.90:FF:000001">
        <property type="entry name" value="protein mab-21-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046903">
        <property type="entry name" value="Mab-21-like_nuc_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046906">
        <property type="entry name" value="Mab-21_HhH/H2TH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024810">
        <property type="entry name" value="MAB21L/cGLR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10656">
        <property type="entry name" value="CELL FATE DETERMINING PROTEIN MAB21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10656:SF70">
        <property type="entry name" value="PROTEIN MAB-21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03281">
        <property type="entry name" value="Mab-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20266">
        <property type="entry name" value="Mab-21_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01265">
        <property type="entry name" value="Mab-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mab-21-like nucleotidyltransferase" evidence="2">
        <location>
            <begin position="123"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Mab-21-like HhH/H2TH-like" evidence="3">
        <location>
            <begin position="306"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY58917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="419" mass="47761" checksum="8EAE19817A7FB4DE" modified="2024-11-27" version="1">MSTKDLPQVSNRLRFTRPEEIPLRYRDSASLLHEGVTNRCVRAEPSQTQGRPATMLVPSDMMTAQSKLLYQLNKFYGERVQTRKGTVAKTGREVCKVVQDVLKEVEVQEPRFISSLNDCNGHFEGFDVISPSEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQACDKCSYRDIVKMVADTTEVKLRIRERFVVQITPAFRCSGLWPRSAAHWPIPQILWPNPNLVAEVKAEGFDLLSKESVTLQGKQSSMEGDAWVLNFCEAENRLLQGGCRKKCLSILKTLKDRHLELPGNPVTSYHLKTLLLYECEKHPREIEWDETCLGDRINGILLQLISCLQCRRCPHYFLPQLDLFKGKSASSLENAAKQTWRLTRELLTNPRSLEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URE1</accession>
    <name>A0AAV4URE1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoenolpyruvate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ppsA_7</name>
        <name evidence="1" type="ORF">CEXT_157961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013312">
        <property type="protein sequence ID" value="GIY60327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="206" mass="23653" checksum="EBB5198A2CD82C00" modified="2024-11-27" version="1">MEKRIVWQKPWRASNYQMKTAKHSFVVICRCIISLNEKMEDILLRHVKVLDAFNFYAQTGVATGTVSVEDTFEYEMYLFGEKIRDLGKRVNATSCKSMTLLGQTPAIGLGFHLVNISAPYAFKNLSLGFAVDSEGQSELLKEVHFDIKQLTRENFQRTFKISFNGAEAKERYVFVEELKGTKKQEELAPEVTKPRWSMVKHIAAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUC0</accession>
    <name>A0AAV4UUC0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_151801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013460">
        <property type="protein sequence ID" value="GIY61389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUC0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10429" checksum="15DAB1A0E8E16BD8" modified="2024-11-27" version="1">MKATANQEKKNQNVFEQNIDRYLRTPTKTSPKYGMMLIFRDSEKKKRDVNVCTKHCTFKQPDTKKGLGTSFDGSFRGGAGWSVRGLPLSTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWJ1</accession>
    <name>A0AAV4UWJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_191991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013580">
        <property type="protein sequence ID" value="GIY62113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8982" checksum="9C58A9898F36D487" modified="2024-11-27" version="1">MAERLPNKAALREIPWGVPPSNEREKQMIGGGGASSEACLPPLMKCDKRGLPKGGLVRIIELVHYLQEKLDNRTFFCIGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0S8</accession>
    <name>A0AAV4V0S8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_698721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013745">
        <property type="protein sequence ID" value="GIY63453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0S8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY63453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9827" checksum="681DB7AC7F2C2EEE" modified="2024-11-27" version="1" fragment="single">MWTVIIYHLLGSHHTFDNGFIHNFFPRFFKFAVTLGLAMLAVQTLIPLNHSSPQNSTEEEREAPSWLAQLLTAETQSEKSRSPQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4F5</accession>
    <name>A0AAV4V4F5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_774241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013964">
        <property type="protein sequence ID" value="GIY65122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4F5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="19544" checksum="86DEB238AE440546" modified="2024-11-27" version="1">MPRDSARIKSTVSSRALSSPRSGHVGSEPLNSSQPTLPSQQHLGMVKKHSASFTSLHGKTARHSGTCQVGPDMPLTVLHCSPYSSSFFSTDTKGPSLIQFSNKATSPSHHLYNSLVGSQVNPLNDSQELGTQMGMFCCSFRFHFRSEFATSLVVVGFFSYAMLRLRPLVKGGCLSAWMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4I0</accession>
    <name>A0AAV4V4I0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Voltage-dependent calcium channel alpha-2/delta subunit conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CACNA2D3</name>
        <name evidence="2" type="ORF">CEXT_424751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013954">
        <property type="protein sequence ID" value="GIY65052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4I0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013680">
        <property type="entry name" value="VDCC_a2/dsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08473">
        <property type="entry name" value="VGCC_alpha2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Voltage-dependent calcium channel alpha-2/delta subunit conserved region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="258" mass="29811" checksum="34D310321A926C54" modified="2024-11-27" version="1">MAESKTISLRSRLNGEIFFGEIDNVLFDTLVQGNIFRRIRMYDYQAICIDLIVPSGPGTLLRTPLRHIKNIIHWIWTKMVMYFVQTNVFPWLSDHVAQASDYYEDEQGNDGKVTRQNKTRARPCDKEFTLYEMRPIDSWGQTKGVIPNCSSIEDCDKNYIVQMVPYTNLMMLVTYSEECSCDNSSQTESNTQTLELEEVIYDEDERCYRMRNGTLRKLPEPCVHHHPEEGSLGQQCGLGSFLRASIYLVVGALLLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V737</accession>
    <name>A0AAV4V737_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ZRANB1</name>
        <name evidence="17" type="ORF">CEXT_616551</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01014064">
        <property type="protein sequence ID" value="GIY66037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V737"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070530">
        <property type="term" value="F:K63-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030177">
        <property type="term" value="P:positive regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071947">
        <property type="term" value="P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035523">
        <property type="term" value="P:protein K29-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990168">
        <property type="term" value="P:protein K33-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22767">
        <property type="entry name" value="OTU_ZRANB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041294">
        <property type="entry name" value="AnkUBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049768">
        <property type="entry name" value="ZRANB1_OTU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF28">
        <property type="entry name" value="UBIQUITIN THIOESTERASE ZRANB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18418">
        <property type="entry name" value="AnkUBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0879">Wnt signaling pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="15">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="15">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="15">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="16">
        <location>
            <begin position="424"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY66037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="706" mass="80243" checksum="6448CD670B97BAEB" modified="2024-11-27" version="1">MSQDESKWTCSMCTFENWPKSIKCTICRSPKQSQIISQDKSQDIYMITPLISDACSPPAAQSSSTPSNPHNKWSCPSCTYLNWPRATKCTQCATKRRASPPPELKNNTPSQDQSNNASMDTTTACVHSDNYHNDRNKSWSRSIKWTCATCTYENWPKSIKCVLCHTPRPKMDQSCKTLTENESRSRQRSNQYDVQTVYPPVNCLRRNDHLSSETTEIQVSTPLACASELSRTPNNYLEECRLRNTRRNNREVDWTWLNACMGVVDGDAEPVIEYLSVGGDPGRQLNANEVALLKRPSAFDPGYTLVHLAIRFQHEDLLTLLLSHTEMTRPAAKRVPADISRTIAADIRHMIAASLKQRRGEFPCYFVTDCVTFSLPAEIEDFNPIVQEKLFDDLLDRDAQKELEEESPIINWSLELTERLGSRLYALWNRSAGDCLLDSALQATWGVFDRDNSLRRALGESLCEAAAVLYPRWKEAETLQANLLQFSLDETQWQEDWAMLLSLASQPGSALEQMHVFTLAHILRRPIIVYGVKYVKSFRGEALGFARFEGIYLPLLWDPTFCWKSPIALGYTRGHFTALVAMEPDSEDSLGAGANIRTGDDLRVIFLPLMTMDHQRLPVHFLTQDELGREEEIMKQWLDCCVTEGGILVAQQKILKRPYLRRRFGSGVNTERSIDCTYNAFRVGLRLSRPRRGLFCVIASPCTFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7I8</accession>
    <name>A0AAV4V7I8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_616651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014064">
        <property type="protein sequence ID" value="GIY66056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10135" checksum="FDF014CA61FB46C0" modified="2024-11-27" version="1">MLTSSGQALSRFTAQQDFEDTNGKVSQISIEDSFEEMTLQELPDEDDISFKIENIINNDITMTESIEFENDQGNAFKRSKHNYYNDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8W2</accession>
    <name>A0AAV4V8W2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_151541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014069">
        <property type="protein sequence ID" value="GIY66079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8W2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14428" checksum="DA24CA461506BE4F" modified="2024-11-27" version="1">MSGSWVDSSMKPLNGPRNRPNRINTVSETSFHTVYWTESPRCPQQILRSPSIGDRRDFYLRQQINLFHNWLTGACLALGLILHNEAAQWATKSANRITQCLLRHHFAVYWTESSRCNPTTSAIAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VGI0</accession>
    <name>A0AAV4VGI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_121801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014495">
        <property type="protein sequence ID" value="GIY69148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VGI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8148" checksum="192FB33D61BFF181" modified="2024-11-27" version="1">MLRCVWKWHFEDEASYHTLNLPSDDEPVSIACGKDFCSAEDSYCKILYTGKAQSMGIKQKEAQLWGSGLNCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJ22</accession>
    <name>A0AAV4VJ22_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AAA_11 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_77924_1</name>
        <name evidence="1" type="ORF">CEXT_379911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014599">
        <property type="protein sequence ID" value="GIY69839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJ22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17310" checksum="0B1BA4864ADA994C" modified="2024-11-27" version="1">MKHFYKTKVLLCTRTTQALTEIGFKLCEGTINFVIIGKHTDTHQQLRKYELDNLAAKTLSEDNLGDEESNGRLLENAKIDIIRNCDKIISLIQNAYDDLVAKACTDGDCIAQMCCIICEANLCTEPEILIPLLHGISKLILIIIDHYFIEHMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKE8</accession>
    <name>A0AAV4VKE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_347091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014665">
        <property type="protein sequence ID" value="GIY70434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8878" checksum="A655F2CEDCB3FACC" modified="2024-11-27" version="1">MCLAFWKKNRRLSSRGLPIFYEMKSHKASDDTIVEMATKSIMKERATSGNATQREIRDAGLHLQRRFTNVTEEIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VSA6</accession>
    <name>A0AAV4VSA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_687431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015022">
        <property type="protein sequence ID" value="GIY73013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VSA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10601" checksum="4249F35F57B53BC9" modified="2024-11-27" version="1">MKRIIDNFKTSKCEKHLFKEFYKTLVGLLPSLDVQFENPILNSFTPVILERFCCLPEHRSRFEDGYKQLLYFHEKLGEAVYYVLNNMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0L4</accession>
    <name>A0AAV4W0L4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_466831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015335">
        <property type="protein sequence ID" value="GIY75409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0L4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12434" checksum="B7A494BE8B99780A" modified="2024-11-27" version="1">MPGVSLACGNPIREGLVQQLCKADDSTALLIVRPMLKLGICAVYCSKLSISPSLREYKTAYEICFDTRPTMPYVSIFRKKAIDLNKRLKEKFHPRSHEHIFVSCSTETKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W940</accession>
    <name>A0AAV4W940_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_614821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015870">
        <property type="protein sequence ID" value="GIY79317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W940"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13644" checksum="AFA1E074C299F9A3" modified="2024-11-27" version="1">MFIESNVNIVSRQERESPSHPKNNVSEKAIKQPPTDERAEEATDEIRSNSSRLSPQSCTLPPRECESRSESQLKRFSGLFWRMEFAAVQRMQKPCFCRRECVSELFGERGDSLVIKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEY3</accession>
    <name>A0AAV4WEY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_267171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016102">
        <property type="protein sequence ID" value="GIY81292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18385" checksum="55A19E40315E4FE1" modified="2024-11-27" version="1">MGFGDSFSFRVASEECRRRRIWIFWCLSKFVCVGFFCRKKILKAEEKNKVMSQPLNVDKGKSFACNSSLLCSISSDRKCGLYQHPQYEGKNGFIHIENGIRKTIIGDVVDCPCVIWKIVGRLTPDNLIVDVRMLLLAVRNQRVFSFQKAETAKDTAEFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WF20</accession>
    <name>A0AAV4WF20_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">AVEN_169167_1</name>
        <name evidence="13" type="ORF">CEXT_381721</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016058">
        <property type="protein sequence ID" value="GIY80863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WF20"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071222">
        <property type="term" value="P:cellular response to lipopolysaccharide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006955">
        <property type="term" value="P:immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051713">
        <property type="entry name" value="T-cell_Activation_Regulation"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25466:SF9">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25466">
        <property type="entry name" value="T-LYMPHOCYTE ACTIVATION ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="12">
        <location>
            <begin position="47"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY80863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="30061" checksum="AF9BD7259BEB363B" modified="2024-11-27" version="1">MAIKARVTTVPLCLPRQSPLPFYGKNLHSICIRIKTVYRESGGIYSPILSGGREHSVSGKVGESVVLPCEVDTHNCGRIYVITWTKHMGEEWRRVYLYSDTHSRPMGAFAGRAHFVLHNNSNAELHLRSLGVADEGTYKCDVTYVHGKCPSLTFTKLYTLTNNFTKIESPPKCRAAFAKETLHLHHFGKLVLSITRPLIPFTLGSENHLFTSHQISKEKIDTPFRAPQPPSPSPPLPIDPATRCKWKSVIDSQNRKRRHNRFRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WK65</accession>
    <name>A0AAV4WK65_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_265911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016217">
        <property type="protein sequence ID" value="GIY82174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WK65"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY82174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13723" checksum="96BDF3657F7D0773" modified="2024-11-27" version="1">MRLPPKAFVCFSPSCNAFTLKKSGNQSNKRSFNLYSNRTLGPQVVDSALSFVCPGAHPWNFRKSDICIRRAPSAAFYSPSRTFPLFELAFILQVSVILALTSFFNENAFYSGMFLENLTSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WW34</accession>
    <name>A0AAV4WW34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_162981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016712">
        <property type="protein sequence ID" value="GIY85920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WW34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17272" checksum="A7D371E5864471C5" modified="2024-11-27" version="1">MKKNNKEEGKKMAEKPSAKINLREHICIAKEFLARPTLAKKHRTKQRQEFYTEYSTILTPEGSIKEAAVGILRTWGKHSLLGNEKKSIERMEKNKKEEGKKTARNRRRRLICENIFASPKNSSSTQLLQRKQNKAEAGVLYGTPYYYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9V5</accession>
    <name>A0AAV4X9V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_704241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000041">
        <property type="protein sequence ID" value="GIY91691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10862" checksum="6C6A014971AD566F" modified="2024-11-27" version="1">MPNSSNERRKKGYRGPYAGDLRVTPTALISKDSERKARVCHCDFGAGYPRIILLSSGTCLFERVPLRTRARKWVSRHVNNLPLLGEVKGRTCATMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAX2</accession>
    <name>A0AAV4XAX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphatidylinositide phosphatase SAC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">inpp5f_2</name>
        <name evidence="1" type="ORF">CEXT_795551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017429">
        <property type="protein sequence ID" value="GIY91568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12472" checksum="9E87DD9CB6636617" modified="2024-11-27" version="1">MDSSSESEEDSVLHHKAYTTTGFHGHISDRTLSSDYSEFSDVDEQEMMLSTECLNNGANDNKHDAVLESCGILATFNFKTNQPNNFVFLDDSITLTKGAITQKWMILSWMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCU0</accession>
    <name>A0AAV4XCU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_43431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000136">
        <property type="protein sequence ID" value="GIY92409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="19562" checksum="A8EB4BC0A7ADEE37" modified="2024-11-27" version="1">MDMEEMDLYDAQSFLSETQEINLIKPHSYALDAVAKYRKFISWWFFVRNTPRIMASDFRVLLHFMKTCKLPFETFYEDIASLGSIISTFTENYGILRKELISLSEKVENFVKYAAHFNPESSNEFFDMYNDIAMYGCDVLQYFLNCKESLDGYIKVRHKLATSLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLW1</accession>
    <name>A0AAV4XLW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_390991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017950">
        <property type="protein sequence ID" value="GIY95679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11834" checksum="3F37F20D6F426BF3" modified="2024-11-27" version="1">MHRMHSHYPGTSEKPRLLKKKGLLKQDHIVRERHPPIAFILLMRRMHRLGHQRSLVYLRVGNASSENEAFTLIASESAKMTLFANFSSPLPLFWDFRNLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM16</accession>
    <name>A0AAV4XM16_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_635461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018019">
        <property type="protein sequence ID" value="GIY96201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13270" checksum="1633579A54A1854B" modified="2024-11-27" version="1">MIYYHDEHRLRKIRTDNDKSMHQGKNLKTSFGHIHSEEKAPNLFLIIPSVLPSISVGRRKTRSPRFCEVIERGVKPRLSTLSFGGDFNELRRDSPNERLTYRLVPLLNSHCAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPL8</accession>
    <name>A0AAV4XPL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-directed DNA polymerase from transposon X-element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X-elementORF2_256</name>
        <name evidence="1" type="ORF">CEXT_718371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018066">
        <property type="protein sequence ID" value="GIY96598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11896" checksum="7021E2DAE7AAC8F2" modified="2024-11-27" version="1">MTSMALLLRLMNCNSPLKKSHLTSPGPDDIHQTLINHLNFKSLTLLLSLFNRIWTEGTFPTQWTRATILPILKPGKEPQEVTSYRPIALTSCLCKTMERMVNAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPV0</accession>
    <name>A0AAV4XPV0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_158043_1</name>
        <name evidence="7" type="ORF">CEXT_149431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01000755">
        <property type="protein sequence ID" value="GIY97206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="6">
        <location>
            <begin position="33"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY97206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="355" mass="41285" checksum="8FD318787751B6FC" modified="2024-11-27" version="1">MANKDSCLAYLVIAMTIVTLARYQLLGSYHYMKRLGYNVCYADTDSLMVHQWPVDDCDKVNSYLGLPHVELKYEQRMKRLLVLSKKRYVYETQQNQIVTKGFQKRINGVVEYMSRTILEAVWNEIYSLDPHQDTTVSQASRGWIVWVDTLLQVSYMCRNPKKFSILKFAVKTKNLEDYKSKSCAAVRMLEKYPEKANDYIEYTYSRSDVAATEASKWIMDAEDCELVNFEQLFMSQKKMLCLLLNIAFWKLVNPIEQCDMVLNTMRWKCFVLAELKHRLETGKGIVLKEECFTQTFWLDTEDTCRDPCFSIEPNTLDDIRGCKKLCTGPTFSRDIGRKCCEIETVLGATCTNTCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSX5</accession>
    <name>A0AAV4XSX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_277001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000889">
        <property type="protein sequence ID" value="GIY98142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9058" checksum="1F0B3BEBBD266BA5" modified="2024-11-27" version="1">MITELEPSRNSLQRRAHAQQTKAEDNEEISFGDKSLPQLSRAAEIYISPCAPPNCKCSFDGTQNDNPAPRGKYEYDRSRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXY0</accession>
    <name>A0AAV4XXY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_67071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001088">
        <property type="protein sequence ID" value="GIY99822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11594" checksum="078CB176BF5EFB50" modified="2024-11-27" version="1">MRPAMESTKSSRPSSCAASSFPSPSATTCCTCTDGRHPQVPPATPKRHHVEPCPPLAHRGSEGTEDVLVLFHVHRSHGPSTWHSAVHQRMGISSQRRRVDVDHRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZA6</accession>
    <name>A0AAV4XZA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_517001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018428">
        <property type="protein sequence ID" value="GIY99530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY99530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21529" checksum="CF2F9F7C7854BF39" modified="2024-11-27" version="1">MINADHPAATTGRSPKDQCPLEGASLQSRVTFSWILGLLKKSLKNSLHQDYLLPLCSDLKSSRIVKLFQEACLNLSKQHFLNEEAENLIDGEAAFETQNRNRTNFSYIYPNGKSLFTILLRISKNFLTLASILEIVYTVLYFLPVYFLSLLLDNEKERQEWHNYLYAAALFMTLVFALSPTLRENIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0A4</accession>
    <name>A0AAV4Y0A4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome c1, heme protein, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Complex III subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Complex III subunit IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Cytochrome b-c1 complex subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">CYC1</name>
        <name evidence="24" type="ORF">CEXT_611571</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="21">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="21">Binds 1 heme c group covalently per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="19">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with FLVCR2; this interaction occurs in the absence of heme and is disrupted upon heme binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001167">
        <property type="protein sequence ID" value="GIZ00533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0A4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000002">
        <property type="entry name" value="Cytochrome c1, heme protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000003">
        <property type="entry name" value="Cytochrome c1, heme protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021157">
        <property type="entry name" value="Cyt_c1_TM_anchor_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="CYTOCHROME C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266:SF3">
        <property type="entry name" value="CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81496">
        <property type="entry name" value="Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 21 22" id="KW-0349">Heme</keyword>
    <keyword evidence="12 21 22" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 21 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="23">
        <location>
            <begin position="88"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="21">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="21">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="21">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="21">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00040084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00062753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00079825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR602326-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="GIZ00533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="34484" checksum="C445F1CB12B284C5" modified="2024-11-27" version="1">MAAVVGKLLRNDFIRLQNSYRPRKYSSFPQFSQNTKKVLTYTGLALTGAAGLALAIHETVSISAGELVVHPPKHPWSHNGPINALDHASIRRGYEVYKQVCAACHSMRFLRYRELVNVSHTEEEAKAEAEEIMVLDGPNEEGEMFKRPGKLFDTFPSPYENEEQARAANNGAYPPDLSLITSARHGGEDYVFSLLTGYCDAPAGVELAEGQYYNPYFPGGAIGMAQALYNEIIEYSDGTPATLSQLSKDVSTFLRWAAEPEHDTRKRMFIKVMLILTLLTGVSYYYKRLKWAPLKSRKIVFKPHQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0J4</accession>
    <name>A0AAV4Y0J4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_350311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018589">
        <property type="protein sequence ID" value="GIZ00837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0J4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="26561" checksum="03AD42A530657181" modified="2024-11-27" version="1">MGDFQVYNITAYDSPHINAHPLVSSTYYRVEPAPPSAKRTAKVPVPIYYTRLSPYVMISSLLCDPNGQKGGGMGNAAHINVHPLVSSTYYRVEPAPPSAKRTAKVPVQIYCTLDYHHALINLLSGGTHSAISQKDCESSCPNLLHSRLSPYVMISSLICDPNGQKGGGNAHINAHPLVSSSYYRVEPAPPSAKKGLRKFLPNLLHSRLSPYVMISSLLCDPNGQKGEGMVKAGTALKVHRNIVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1I5</accession>
    <name>A0AAV4Y1I5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_701771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001194">
        <property type="protein sequence ID" value="GIZ00694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1I5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11341" checksum="2E2AD3397A0015FA" modified="2024-11-27" version="1">MRITIYHSENHNNHIISKHYDIHYPFHREFQHHSKTRRITIHKITSDAVKHLITFSIVEKTSIISPVINVITFDGYPENREARAATDETKAGIPLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5J3</accession>
    <name>A0AAV4Y5J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_168371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001298">
        <property type="protein sequence ID" value="GIZ01419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9231" checksum="94EF6FBCE1D728AD" modified="2024-11-27" version="1">MFWILSHMDMSYSYVLVIQKSIMMEFESSEVFPDDLKYSDDLKYSDDLKYSDDLKYSDDLKYSDDLKYSGDLKYSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8B3</accession>
    <name>A0AAV4Y8B3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_778821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018845">
        <property type="protein sequence ID" value="GIZ02705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8B3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10979" checksum="30C43E5EE054A6C7" modified="2024-11-27" version="1">MLRIPFEGLRLKCFFSLGCTCFLGRIQLDIRPIAKGTTFPLINSQDKIKHASSAIHIRWNAWLLCNVLSLYLKCKCNSLETPLPLTQRIGVSSTPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y950</accession>
    <name>A0AAV4Y950_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_706971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019014">
        <property type="protein sequence ID" value="GIZ03932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y950"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8454" checksum="67CBFE15485A1781" modified="2024-11-27" version="1">MESKSDIEPAVCACVENCKCFDGETEIAHVALFCPCCRNKNMQRAMWFQSRKVFVAAAKKAKKSCMFLWRQLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAM2</accession>
    <name>A0AAV4YAM2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease HTRA2, mitochondrial</fullName>
            <ecNumber evidence="5">3.4.21.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">High temperature requirement protein A2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">HTRA2</name>
        <name evidence="20" type="ORF">CEXT_126841</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="18">Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Can antagonize antiapoptotic activity of th/Diap1 by directly inducing the degradation of th/Diap1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues.</text>
            <dbReference type="EC" id="3.4.21.108"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.108" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01001613">
        <property type="protein sequence ID" value="GIZ03509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.120:FF:000004">
        <property type="entry name" value="Serine protease HTRA2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22939">
        <property type="entry name" value="SERINE PROTEASE FAMILY S1C HTRA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22939:SF129">
        <property type="entry name" value="SERINE PROTEASE HTRA2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 20" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="16" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="PDZ" evidence="19">
        <location>
            <begin position="242"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="GIZ03509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="34408" checksum="4F813DEA51880977" modified="2024-11-27" version="1">MFNFLADVAEKTKNSVVYIEIVARHPISRQSIPISNGSGFIVKSDGLILTNAHVISHHGRVIVKLYDGQEYEGIVESLDTESDLATVRIDAKDLPVLPLGQSSKLRAGEFVIAMGNPLTLSHTITAGVISSASRQGKDLGLHKKSDYIQTDAAVNVGNSGGPLVNLDCEAIGINTMKVTEGISFAIPSDRAVEFLQRTEKQKCSTNTNRKQKYLGITMLTLTPIVIRELQERNPEFPNVDHGVLVWRVMYNSPSYESGIKHGDVITAINGKEIHSASDIYNLLKSEDILSIHIIRRKKEFDVMVQLMYPVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBP8</accession>
    <name>A0AAV4YBP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Corticotropin-releasing factor receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Crhr1</name>
        <name evidence="1" type="ORF">CEXT_538591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019010">
        <property type="protein sequence ID" value="GIZ03884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13064" checksum="308EC506351E6752" modified="2024-11-27" version="1">MSSCRFRRHFRQVSEVQTVLRKAYVRAALRRNPNHRYTWKCRTTRASQTSTYVSNCDNSVTDTALVRTGASPRSVHLLREVRTYDKGASGNTVGEEGQYTGQRKISVISGIHTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD74</accession>
    <name>A0AAV4YD74_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Svep1_20</name>
        <name evidence="7" type="ORF">CEXT_13481</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001692">
        <property type="protein sequence ID" value="GIZ04117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD74"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.10:FF:000032">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003410">
        <property type="entry name" value="HYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052071">
        <property type="entry name" value="SCUB_EGF-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24046:SF7">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24046">
        <property type="entry name" value="SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02494">
        <property type="entry name" value="HYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50825">
        <property type="entry name" value="HYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="795"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="5">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="HYR" evidence="6">
        <location>
            <begin position="204"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ04117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="929" mass="103216" checksum="BCCD4D35E1D1FD07" modified="2024-11-27" version="1">MWIQFNSHETSGVFFTLYSVESRHLPIGKKILLQADQAGVLIALFSNIVPDTFIPYLKNVPINDGQWHHLVVMWNGETGTVSLITDAAVAGTVTGYAENQYLPQNAWVNIGAPLDAKNRAITSSGFHGRISRVNVWNRPLDVSYEIPIQFRSCKSAPVLYDGLLLRWTGYDRVDGTIEREGPGTCGEYVCPAGYTGESCSIQTQDKSAPKPVECPQDIWVVTSNTSEQVTWKEPSFVDSMHTLYVMEHRGYTPGQTLSRGIHQLSYIAKDAEGNTARCDFRIHILKEFCPLPAPPVNGQRHCSDWGPNGRFKVCTITCNSNLEFSQPVAKFYTCGAEGIWHPPSGHGSSLVFPACSARKSAQKIFKIDMNFPSSVVCSESGKKILQSRIENNLRQVNREWRICSDNTPGICTGLKVKVHCKQARAKRQLDNNELYVVEIEFPANKDPIVNINTQQQSTVQKVLESAILQNQAFDIQDTLPNVVPDLTSLDMVTDYTCPAGQVVVAPYCVECGLGSFYDNSSRSCLSCPVGTYQDGTGHLTCKPCPNISENQGITESIGARSVQECKERCSPGMYYDDEVNLCRPCGHGFYQPNEGAFSCIACGSDLTTKSDKAVSIQECREECAAGFQLTRDGNCEPCMRGYFRPKGAPSCIKCPPQRTTPSISAKSEAECSEELCSPGYFMDSNRHCIECPKGSYMDHEQQESECRPCPQDTTTATNGSTSESDCTNPCLVDGQMRLCQANAFCVFREDVDSYACECQPKYRLENRTGECVSVCESYCINGGTCEVNSETHEPMSGAVIFIILLVLLIWMICVRSTTRKNLPKKMPEPAIDLSSSQTNFYYGAPQPYAESIAPSHHSTYAHYYDDDDDGWEMPNFYNETYMKDSLHHGKGNSLARSNASIYGNKEDLYDRLRRHQYQGKKDSDSEDQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDP4</accession>
    <name>A0AAV4YDP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_771581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001719">
        <property type="protein sequence ID" value="GIZ04344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12233" checksum="30D97194EE3556A2" modified="2024-11-27" version="1">MTQVTQWTSSSDETVTIQLNPTSSPAPHSSCSHDVSIRSPSPLTKEQEIGDQLASIWWPLAPQASCSNLGDGMDVSLQKLEAERLNFSTRMLRQCSPSSGNFCLRDKIPLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFL7</accession>
    <name>A0AAV4YFL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_82051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019235">
        <property type="protein sequence ID" value="GIZ05201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9563" checksum="35537E7F10E9A80B" modified="2024-11-27" version="1">MAERKRPNKDVESSFPRISKREKECVLQTLETLTEEDVEVRVAQTHLLLVSASADDIFMFGTISELPWMLICAGNPLKKNFRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4N0</accession>
    <name>A0AAV4M4N0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_91861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001824">
        <property type="protein sequence ID" value="GIX66822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4N0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8435" checksum="BEB0F62EB071BC90" modified="2024-11-27" version="1">MFFNEMRGDSHSRRFRGEEVPVVSRRESVTDTGSSAFETRALMPLGARFGDGGPDSKFLAPLRGAPIRLATFKLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M862</accession>
    <name>A0AAV4M862_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019508">
        <property type="protein sequence ID" value="GIX68611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M862"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9716" checksum="E4A210BCAA4EF52D" modified="2024-11-27" version="1">MIFWIVVLPVNRLQRIFGYKAALTQQSFEATIICERIERNCPISCQIVVVMPLCCIPVISVAGHLCHFRRPSWSSSSWKLDFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBX9</accession>
    <name>A0AAV4MBX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_659831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002060">
        <property type="protein sequence ID" value="GIX69514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="23961" checksum="2D6084D8E3E74869" modified="2024-11-27" version="1">MGVTDEEINAKEIYQQISSLECGIAGLEVHLQYNIVLKNAKQKLLNNRTKQNHAEQKFLKTPNAYPKYGQICNDILCIQQTFDIQRTFPKLFVILPIMQKKTENDLDKLGLFMQALVTAPASNLNGNDSHLPKIVLPQVALQSLPNALFLIIKYFNPNLNFIEASIISLNLTNRHPIIIALSKFPPSSDNTLFILDLENLIQIGSNVILCGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEF8</accession>
    <name>A0AAV4MEF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TD and POZ domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Tdpoz1</name>
        <name evidence="2" type="ORF">CEXT_529741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002124">
        <property type="protein sequence ID" value="GIX70235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="162"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="37704" checksum="F2148016394DF87B" modified="2024-11-27" version="1">MDEKNEHDNKCRIVIFLNKEKDGIDLDIALNFQFALLAEDETVLISSPTAENCIFQERKTFFGFHLGADEIKKRERKNWNFKLKQTKKELVESKNIFLKDNVLSLNCECTICTGVYLVTNEKHDFGVISSDSRTEIFKATPRIPSSNLQNHLMSMYDDAILSDMELRTWTKTFRVHKNILSARSPVFRAMFQADMKENAMKYVEITDLDDETLDKMLLYFYNGIFEVHHWESASELYQAANKYQILTLKRLCSEFLASWICATNACKILMLADMHEDEELKKCAQTYILSEKNIMCSDNWKKFMNDNLQLAAEIMYWKCTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHV3</accession>
    <name>A0AAV4MHV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_487141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002201">
        <property type="protein sequence ID" value="GIX71217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12357" checksum="3F3A4BD7EFCB717F" modified="2024-11-27" version="1">MSGACLSAPRPLLPQRHLPPLSPRSNDEMIGRPTISPGIDAWGGSAGCQGATARDNPGFRVGLGRIWRVPTCKRSFRELFWIFGLLRIRLSSSPGRIQQLPTYKRSFRELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJJ1</accession>
    <name>A0AAV4MJJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019787">
        <property type="protein sequence ID" value="GIX71772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19897" checksum="20C9340849B303E9" modified="2024-11-27" version="1">MPTYKTFKSTDCNISCKYFPNHFIEVRFYIHEISTKDKLTICQEFPNETEEHIDFSIKLDFKNYTTYATMIMKLRLNDPKMPLLQVEIKSKATDLEGNGLNKEMQSTYNVASNKEITLHQPLISASNWNKLNNDSLCFYTAIKVLNKSNIKRYFGFKKRLYEGKCSCSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNR1</accession>
    <name>A0AAV4MNR1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">insr</name>
        <name evidence="16" type="ORF">CEXT_264501</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01002482">
        <property type="protein sequence ID" value="GIX74182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005899">
        <property type="term" value="C:insulin receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005009">
        <property type="term" value="F:insulin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043560">
        <property type="term" value="F:insulin receptor substrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042593">
        <property type="term" value="P:glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051897">
        <property type="term" value="P:positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000528">
        <property type="entry name" value="Tyrosine-protein kinase receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002011">
        <property type="entry name" value="Tyr_kinase_rcpt_2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF525">
        <property type="entry name" value="INSULIN-LIKE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00239">
        <property type="entry name" value="RECEPTOR_TYR_KIN_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIX74182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="394" mass="43816" checksum="1349873942D03099" modified="2024-11-27" version="1">MIEGSHAFPKGNWDKVHLEWIQRKIIDLNGKPLTHCAAKTVNESASLRERIEFLQEASVMKAFNCHHVIKLFGCSFKRPDSEDNRGRSPPTLKQVLQMAAEIADGMAYLSAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGGRGLLPVRWMSPESLKDGIFNSRTDVWSYGVVLWEMATLASQPYQGLSNDDVLNFVVRGGLMEKPENCPEELDNLMKMCWEKSPKSRPTFVEIVQMLSAHVNEKFCTVSYCFSERHLSNSVDVEEVATPNTPLRSSICEEDTNEEQIYHYFPSATLLPENNANGDGLVNVDIEQLPTTSDSLIGACSAVETDSVAVGMNSNEGSKAISVSYSDESKGSKISTLSNGSIANGHVVYACNKKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N452</accession>
    <name>A0AAV4N452_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_753211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002911">
        <property type="protein sequence ID" value="GIX79216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N452"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7639" checksum="6778C3A0E2B523B6" modified="2024-11-27" version="1" fragment="single">MSPLYHLYLVSMIIAHFCKLGRTPKVVEWSSSACLYTPKDGKYREMESQCMLEPTASHEKCKNLSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6R6</accession>
    <name>A0AAV4N6R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_354271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020489">
        <property type="protein sequence ID" value="GIX79391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10081" checksum="7B631910EC686E6F" modified="2024-11-27" version="1">MKGGRNRFNGPGSPTPVGISSLIYVNSTLQIYLRSCDVLTMSIGCPRWIHQVFSLNHHWECSRDIGLRLRDVASCTLSMKAIAICLRFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8L5</accession>
    <name>A0AAV4N8L5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_497321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020656">
        <property type="protein sequence ID" value="GIX81157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8L5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="250" mass="28854" checksum="B551BCFBDDFB3208" modified="2024-11-27" version="1">MRLNDDIKNHKFHAPLTYDTTTKILNEPSVFPPNSADLHAAFVEKNRSLVILGVTKRASSDVICRTLQYVYRREEWTAFSSAALSLATYTSITTRTSDKNDWIVLSCVICQIRCTTKCSNLPPTPKLTDVDTDISATRHPVVRQEPPTLCGQDSSNDLQSFFPADLNAAFVEKDRSVTKRARCDIICNSQYAYRIEEWTAFFLRPLFTYYLHIDYELHFRLKNGWYCFRTRNEITNLWVCTYSFSLPGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9X4</accession>
    <name>A0AAV4N9X4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_497141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020656">
        <property type="protein sequence ID" value="GIX81124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9X4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12746" checksum="E53522805E2A3336" modified="2024-11-27" version="1">MECVNLLGQGRPVSQIQLTTAGWLSPSYQIWNALTFLARVGLLAKYNWLQPGWLSPSYQIWNASTFLAKVGRLAKYNWLQPGWLSPSYQIWNASTFLARVGLLAKYNWLQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDT4</accession>
    <name>A0AAV4NDT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_761741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020688">
        <property type="protein sequence ID" value="GIX81569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="16406" checksum="7FFDE11363E12B86" modified="2024-11-27" version="1">MLSCYYRGIIANNQSRRHNLDDFTRGCIITKTKCRRLKCNQYCKCSGVHGHSHSTFLVPEEYFKRQEEVSDSSMAGPRAIKTTDDRYIVVHVRRNRRLTAAEITSHERTIGHVYHALLWTGSCPNVVYIHSDHTLYAVNSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NI88</accession>
    <name>A0AAV4NI88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_361391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020973">
        <property type="protein sequence ID" value="GIX84502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NI88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12015" checksum="7150E87142BF7B70" modified="2024-11-27" version="1">MKIFLTFNSKKTLTVSNVFHSFTGKVLPVTFSLLTCIHFCLCIRLMMLIVLPRGRKEGKQAMHDSGNGRVMGISWQESFKEESSRVESERQLGGLPILCTILYCKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIU8</accession>
    <name>A0AAV4NIU8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Cdc42bpa_7</name>
        <name evidence="2" type="ORF">CEXT_93581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020985">
        <property type="protein sequence ID" value="GIX84583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CNH" evidence="1">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12392" checksum="A21FCA9B66F6ED64" modified="2024-11-27" version="1">MSFIEFFVETKLSSKSVFQAKEILDNTLTLIKSTTCAAVIDPERIVLGTEEGLYCVDLDREGMHGSLLELRWKKVCQLEYIAEEQLLLAVAGKQRFLRLIPVGALDGQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM75</accession>
    <name>A0AAV4NM75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette sub-family A member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Abca2</name>
        <name evidence="11" type="ORF">CEXT_518841</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003556">
        <property type="protein sequence ID" value="GIX85899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000335">
        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056264">
        <property type="entry name" value="R2_ABCA1-4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23321">
        <property type="entry name" value="R1_ABCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="18"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX85899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="360" mass="39807" checksum="F30BD3BBC82605D6" modified="2024-11-27" version="1">MDEAGTRQPFKGFTTDSEHFPKIYHSKAGRRYAVDNLTLTVPQGEVSDFVFGLVGANGAGKTTLFRLLIGEIQPTSGKVIFKGSQSISNKNHQFLGYCPQKDALDGLLTPRQHLEIYAGLRGIPSSEVAKTVEWSLKSLELEMHADRPVHKLSGGTKRKLCTAIATLGDPELVLLDEPTSGMDPATRRLVWKTISRATEAGRSVILTSHSIEDCDVLCSRLGIMVNGRIACLGSPIKLKARFGTGYTLSFRVPENKEDWTCLLNFIHKENPSAHLQVHSGRRIEIALPDENITLSSLFCQLEDCAKMFGIEDLAIDPTTLDQVFVNFVRQQCDTDQDTSMRSESEAMKDMPLETCCTTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQ29</accession>
    <name>A0AAV4NQ29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_164041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021084">
        <property type="protein sequence ID" value="GIX85649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQ29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="10952" checksum="8734E4D163D84307" modified="2024-11-27" version="1">MSGREKHMNLGYVGIRANNISSRACIRARANKNYVILFFKGIPILSPEHSPKKQNTSSPVEQPAINKSKHMEIDGTSYPPRPKSPNKDGFVTPPKHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P126</accession>
    <name>A0AAV4P126_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_387411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003974">
        <property type="protein sequence ID" value="GIX90887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P126"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8954" checksum="BA132D8F7CA87A1A" modified="2024-11-27" version="1">MSIVKSFSLRFRSQCTDKLKYDQGDVVYAAARSHYDFCKVPLIILSFSNSLPHAYGRYLTGALQREANGHPVRSDRHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7T8</accession>
    <name>A0AAV4P7T8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_73901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004231">
        <property type="protein sequence ID" value="GIX93307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7T8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7773" checksum="0A218DAD4798C6CE" modified="2024-11-27" version="1">MAQTGDSPVCDSQSTGQRSSKLRAILLRGDDRNWSEVSLFQVRGVCWQARSDQSSRVVNLPSHFAGKPPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8H8</accession>
    <name>A0AAV4P8H8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_73851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004231">
        <property type="protein sequence ID" value="GIX93298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8H8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12102" checksum="CA8A4E6E4863D59F" modified="2024-11-27" version="1">MFARSFQEDDGKGKSTTGKHFKVLIVAPSAENKACESRKVTNEGVGEVFLKKKEGEKNRLVTLNFDGRFLVRGMRWFEKQKGVPKNYYKSNERTCKEEFSNNQNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGJ4</accession>
    <name>A0AAV4PGJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from transposon BS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RTase_397</name>
        <name evidence="2" type="ORF">CEXT_261781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004656">
        <property type="protein sequence ID" value="GIX96497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX96497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="272" mass="30477" checksum="78C02DBD77BCF325" modified="2024-11-27" version="1">MSGLNTLQLDCLDGGCWIRKGPSLDFRLPKGKTFKVIYKNTLTNKFSLKQGIPQGSVFSPTLFSLYTADIERELTGECEVGLFANDIVLWHFDPVIKTIEDSIDFDLGEVWTFAREYKLNFNVPKSVTWGADAATLRTTYTFLVRPILEYGFPAYSCASDTSLRKLERIQTSAAIIISENRSQQTVDYLTYSQPILQKKTGAALAFKGNREMQSAFSRFASGHIRCLPFNNKVKVFPTCDKCGLDSASPEHLLDSVNFIRVEVEAEEAGGYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PMX1</accession>
    <name>A0AAV4PMX1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004662">
        <property type="protein sequence ID" value="GIX96552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PMX1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8898" checksum="E8DFC083A3762147" modified="2024-11-27" version="1">MGDRRLFSATEIFLRRKENLTNLLKAALSLKNGTNTDRCSFPPQLTRSLPLRQTIPKNRVTLPKPVTLLQNCHIHISC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQV0</accession>
    <name>A0AAV4PQV0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_83561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004951">
        <property type="protein sequence ID" value="GIX98693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11573" checksum="70291A499A67C299" modified="2024-11-27" version="1">MSTTHLKQNTDILHVGFTNTVVFALQPTQLYLVCLGAKILYSFSSREVFEREPSSSYWNNPFLFRTQWRGGNKQSWKKFLIKYCMRNGDSFRLQQRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSS7</accession>
    <name>A0AAV4PSS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_688791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005122">
        <property type="protein sequence ID" value="GIX99985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7752" checksum="5D5D9DEA54E55BBA" modified="2024-11-27" version="1">MQPSDIKITEQKQVLRLIVAMRCFNLTTVVNIQLQIGFSVQGQLVILYPLQDANHPLLENSPELFSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSV8</accession>
    <name>A0AAV4PSV8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_627681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005187">
        <property type="protein sequence ID" value="GIY00508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043450313" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="53"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY00508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16535" checksum="70B66D2373BE7533" modified="2024-11-27" version="1">MMERQVQILLTLLFVTLAVSNACKYLKFSPMHSYCLPPNPQCELLDTGVTNADKQQLVVKLHNEYRQKVATGQERGAGGMPPAANMLEMVWDNELAAIAQKHAEQCKFDHDCNECREVDRFSVGQNIYEGMSSGPPNTQTEGDGQIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTZ8</accession>
    <name>A0AAV4PTZ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methylenetetrahydrofolate reductase (NAD(P)H)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_516581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005030">
        <property type="protein sequence ID" value="GIX99326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="20480" checksum="D78ED0AFA75542E3" modified="2024-11-27" version="1">MCFVFQCEPVTHDGSRYFKRIRSLRRPGYINVLCISMRAPSLMTDPVTLKRIRSLRRPGYINVLCISMRAPSLMTDPVTLKRIRSLRRPGYINVLCISMRAPSLMTDPVTLKDTIPKAARIHKCALYFNVSPVTHDGSRYFKKDTIPKAARIHKCALYFNESPVTHDGPRYFKKGYDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV61</accession>
    <name>A0AAV4PV61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Diacylglycerol kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Dgkq_3</name>
        <name evidence="6" type="ORF">CEXT_797761</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005150">
        <property type="protein sequence ID" value="GIY00149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF54">
        <property type="entry name" value="DIACYLGLYCEROL KINASE THETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ras-associating" evidence="5">
        <location>
            <begin position="305"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="161"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY00149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="336" mass="38331" checksum="3CF757FEA326FB16" modified="2024-11-27" version="1">MIKHMRGSTMMSAKDMIVLQTQFDLMIIGKSTTRRPPLDRFCDYSVHVECQDFGVADCKECATYVPSRDPSTLMQTHHWREGNLPQNSKCQFCKKTCWSAECLTGMRCEWCSITKDSLSTTVITLSYALIILFVCRLIRRATGACLSSALSAAWRHHAASRLREHPSHGRPPRDHHRGQVKKRETISPRSISEEFSSSGDLKGKEYDESSQKDKEEEIIKVFDGNGSMKTKVQDNHHAKKCIQEQVIILMKRTRQSDSLQNLTRKDGRAAIFIRFRSPDPESGYIKVYPGKLGKLVSRNIEGHQVIQVTSDDEVNDVMERALEKFGLDPSDVMKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q8C5</accession>
    <name>A0AAV4Q8C5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_400251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005763">
        <property type="protein sequence ID" value="GIY04859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q8C5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="164" mass="18616" checksum="EE11234982462A49" modified="2024-11-27" version="1">MFVFLRSMRGAGGFFNCTVDVRGRDAERWSGIPSSSPRNVCNGSYWRAPKDSETSILNSKVPMLHQGRRAPYLYTPKSPPCEFADESAMMFTPNCHKRKRSVPQMSATQSREREESRCIQREVRCGNGEEHRALSWMPPADRKEEEIGGSSSEGSRKLILASYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9X0</accession>
    <name>A0AAV4Q9X0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_744191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005810">
        <property type="protein sequence ID" value="GIY05136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9X0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11213" checksum="E5EC3FB452E68906" modified="2024-11-27" version="1">MFLKGGGNLCGLHGLDTGGMGLFSPLIGYGYSYSYLLCEVSDWKIISRLQCGLRRTACFSPSGKTASMDSAHKRKIVGANKATSKIPRFPYQYNEIGKTNFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA26</accession>
    <name>A0AAV4QA26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MAGUK p55 subfamily member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MPP5_0</name>
        <name evidence="2" type="ORF">CEXT_400311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005763">
        <property type="protein sequence ID" value="GIY04865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY04865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="276" mass="30856" checksum="2422BE589F120850" modified="2024-11-27" version="1">MSLHGESLVMMHSKARTLCCSWRCDSTGHLPDHGDERPTGYDSAVRPLPPEPDAHQSHLRCPPQQQQQQLLHHQSRPRERSVRAQTIFASPTDPPHEEGPAAKDAMKDPKIHSFVNNNVHREMAVDVPDSFVAVTKTAPRYPPPRRKPPRAPPDTSSLKKNGLYHFTAEPATPNHVRSVSSQDGCPDATPERRTPPTPRISELMGKAGEPPQEEEKLIELNQLHRIRKYQVGGSSLLLLTFPFECDHHQVVIGGMELFLLGKYVYPNIVSSPDNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QB33</accession>
    <name>A0AAV4QB33_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_552861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005947">
        <property type="protein sequence ID" value="GIY06325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QB33"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13368" checksum="8C3B4137ADB438C5" modified="2024-11-27" version="1">MSSGWKGKMPSKSHYIYSKAEALSKFCRVLMCSKSLTDDFTLAKKYLKCRTSSEESVGNLLQFHKVPHPLFPQTAAAASRSYNSQIHSSEQQLAGTRTLAKSQEAACWPQEKDGMKKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QEI2</accession>
    <name>A0AAV4QEI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TGF-beta-activated kinase 1 and MAP3K7-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Tab2</name>
        <name evidence="7" type="ORF">CEXT_139771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006145">
        <property type="protein sequence ID" value="GIY07732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QEI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46253:SF1">
        <property type="entry name" value="TAB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46253">
        <property type="entry name" value="TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="546"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="308"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY07732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="588" mass="66682" checksum="F998D4CF31F5352D" modified="2024-11-27" version="1">MASRNIASMHLFLEMKKRFPDLSEDLLRDHIFLYAEDQDKCVSLLQKESKSHFHSSQPFSDKRSSESKAKFKKNVNSSNQETLSSNLKAVARQNNNNSTQQDFTNTQQFNNPSLESTSSPTEIHLSLQLPKPDVPSKPVISNNNKLFVDKSKNMPISSHTVMCHNPSDNMDNRMMFSTTVEHAVLPVESPRIKESTISSLDSTKMEPSKGHAVSLSITPSFPFAQQQMNVYGSSVCTTASHSSKPGRHTTSLNLQLQPQTSDTYPIEISTIPTNIGSPSDYRDFGSHLQISVGSQGATFTALRLQRPHMPQNQSSSNQLPPTNQASFNVSHSSSHAQDSKEYKFPTHLQPLRESNGYFDEMNNYIVDNVMSTKDLYNSDIKHNTKLKSKISSEHVNETNLIHGYQELPAYIMDVKKHQKARLDLVQEELNKEKTICSNLKFMVNKLEQKVALKREKKDSFSYTELNKLKDENRKLILECNDLIMEYDLTTNEQIPLGMTDEDFYSNIFTGPNDGLKCQSNHGKNKKRLSLLPDVTPKSLPSDDENNKNPWKCDKCSFDNYPDLQNCEICELPKDADTFLMIGEDDFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QG55</accession>
    <name>A0AAV4QG55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_246731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006089">
        <property type="protein sequence ID" value="GIY07341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QG55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8554" checksum="3EE71454832ECE5F" modified="2024-11-27" version="1">MGMNGLLKIKVPISLSCYHKSYANRTDFRKLASNIAACSSELTDECDDYSASSIQRVVSRYKAQQLRRRATLLLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QKB5</accession>
    <name>A0AAV4QKB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_654891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006419">
        <property type="protein sequence ID" value="GIY09697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QKB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY09697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14611" checksum="F06CD71D6EBB89FF" modified="2024-11-27" version="1">MEVAAAVVATEAAVEVEDMEGGKGGSGGLGGYGGSGRWWWIWWKERWWRRRLWRRSWRWIWRGSSGGGGGKGGYGGSIGGGYGGGSGGERAAVVEDMEEAAEAEEDMGSGGISKVRLWWSFQLWRKWLVLVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QTK7</accession>
    <name>A0AAV4QTK7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_89851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006812">
        <property type="protein sequence ID" value="GIY12589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QTK7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11867" checksum="02570E123A417176" modified="2024-11-27" version="1">MWLNRIPSLTYISFFRRLHVRNKKDYFIKVLRMLCGRPILWFPKPVIWNLKKKCLEKDYTNGPGFTHFLFGTLLHFHSVMGNTSDISTIHDMIVVKQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6H2</accession>
    <name>A0AAV4R6H2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein CG3556</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CG3556_0</name>
        <name evidence="7" type="ORF">CEXT_497471</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007304">
        <property type="protein sequence ID" value="GIY15926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6H2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015889">
        <property type="term" value="P:cobalamin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002157">
        <property type="entry name" value="Cbl-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051588">
        <property type="entry name" value="Cobalamin_Transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559:SF18">
        <property type="entry name" value="TRANSCOBALAMIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559">
        <property type="entry name" value="TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01122">
        <property type="entry name" value="Cobalamin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="477"/>
            <end position="478"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="494"/>
            <end position="496"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602157-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY15926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="534" mass="60606" checksum="753FC11A23CB7697" modified="2024-11-27" version="1">MPFIYGAMQQLPNRKIFKWNYFACRNYILQSEVLDDTSYCRKFIRIQINNISSELPCENVFVNLSLPETSEEYKFCPDDQQRKPIFIIGSVIVKPYNPYDGYTLSVNLSFTIKDIECINKDSFRCDDNSCVPGSKVCDGVKDCSNGADEVGCETGISAIKGVTEARQNAISWLKKKRYASWGWRDYTSRAVVALYLASDANFNGTILEEELMAKQAELETAVALLRSSLTNSELSMFINSLLVTCHNPRKFYGHNLVTRLKEQVKESKGFTHPSSNYPFIKELQAVAIIALSCNFNNSEEVGKLFLSETLTLYENTVNHFMEVQLQDGSFGNAYTTALITQALISSVQYFKQHSKSWNLKAAIKYLMDHLNSSSTDFLSTYLTLPLLNGKTLMDVSKVNCSANPRKHGDDPVSELKDYLGPKMRVQFSLYIGDEKDVIHTIALRVPENYTGSEVMELAEVEDPKYKFKWKAMSGKMYVYDIANIANDLEMGKFWLLYVGEASNTNHLIHLTTSPDELILKAEDHLVFWYKTASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7N1</accession>
    <name>A0AAV4R7N1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_692481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007329">
        <property type="protein sequence ID" value="GIY16098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7N1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="14290" checksum="BB1B068D35444C2F" modified="2024-11-27" version="1">MQRKRKRVKEKEKKKKEEAFRRDIRKSECVLTTAKCGCRFLEKRIKQTLFKHYEREWKRKKKTKKSEKKKNRKEKEEAFRHDIRKSECELTTVKYGCRFLEKHIKQTLFKHVRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQ77</accession>
    <name>A0AAV4RQ77_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_712831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008256">
        <property type="protein sequence ID" value="GIY23279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQ77"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11834" checksum="081ABF9EFBA28AFC" modified="2024-11-27" version="1">MIITTLTVPWRSSWPIVLIEDHNNNVVLMITTIIIDEDHNNDYASQMLSAPNTRDLSTNECATCEEISHLPYCRRSSTIDTIPDASVIRIPWGQRRQRREEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQJ8</accession>
    <name>A0AAV4RQJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_10321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008172">
        <property type="protein sequence ID" value="GIY22595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY22595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14313" checksum="15D1834729ED31B6" modified="2024-11-27" version="1">MKCSFELEPESIQRTGNSKFILGFTFARLRVSAHIKLLCNATRAIGGVIRRECLVRATFDLTASEQREMTIACLQSALFEKKAVALKPPCPYNLPPTCTLADSCSPIKCSSEFEPESIRFNFARLCPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RUC2</accession>
    <name>A0AAV4RUC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_632541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008303">
        <property type="protein sequence ID" value="GIY23712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RUC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY23712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="273" mass="30076" checksum="C25F04FE7661588A" modified="2024-11-27" version="1">MSRLNQHCRNVRSKSVFDCRNVQSESVVSCRNVQSESVVSCRNVQSKSVVSCRNVQSESVVNCRNVQSKSVVSCRNVQSESVFNCRIVQSESVVSCRNVQSESAFNLVSCRNFQSESVVSCRNVQSKSVVSCRNVQSKSVVNSCRNVQSKSVVSCRNVQSKSVVSCRNVQSESVFNCRNVQSESVVSCRNVQSESVVGCRNVQSKSVVSCRNVQSKSVFDCRNVQSKSVVSCRNVQSESVVSCRNDQSKSVVSCRNVQSEISIQLSGLSNLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVJ6</accession>
    <name>A0AAV4RVJ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_351791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008471">
        <property type="protein sequence ID" value="GIY24961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVJ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9798" checksum="60A2CA8F89813626" modified="2024-11-27" version="1">MLSKRKPITADDIFPYLTILKHPSPQSVPDNILRQSAREDEKSPRLGDRKGKSRATRQRLEGRVGSIARKRSAGATGGYGRRNPGSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S166</accession>
    <name>A0AAV4S166_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein SHQ1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SHQ1</name>
        <name evidence="6" type="ORF">CEXT_178741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SHQ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008815">
        <property type="protein sequence ID" value="GIY27430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S166"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039742">
        <property type="entry name" value="Shq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048696">
        <property type="entry name" value="SHQ1-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007009">
        <property type="entry name" value="Shq1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12967:SF0">
        <property type="entry name" value="PROTEIN SHQ1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04925">
        <property type="entry name" value="SHQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21413">
        <property type="entry name" value="SHQ1-like_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHQ1-like CS" evidence="5">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Shq1 C-terminal" evidence="4">
        <location>
            <begin position="210"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="438"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="462"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY27430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="509" mass="58346" checksum="188BCCAC2918CBC4" modified="2024-11-27" version="1">MPYAKISEYNVQCEDYEFVFSCTPYYLRLCLPGKVQYCDSPKCAYDLDKKTFVMEVPKAVRGEEFKDLDLINLMLRSKKTTSVGGPKIEVLESTDDVEENDEELDIIIDQVPSEDKFGDLNISGQQCGFANSYTHSVFKLKEEAYEIFDVTEPETKTRKIRTEERIRHEKKTFNEDHYIADLYEDEEIKHLLKFIPKWVSLFDEVQKNPSKRHKVIHFTPEEKSRLMDLPNKKYLLDKNQERVVFLGLIDILFAYAYNNRTTEGENTVESAWTINKLSSTLSWLETFSSVSEVAISCIRRSLIFPLYRHFELSATILEDVRKIILLGRKYVIKCLLEIHEMFNLSDPRYILNELFIVDYILWMQTKRCSSKNLVPLATALEKILLTKGDIGLNLVDIETIAQIAWMSSDSMLENTSNRTERKSSMSDLSNDMKKMTLESNSKEAGNTSAATESNSNKECCGSSSSGSSSSSYETDSSVDSDDSIDETDSDDDSNTSDSDSHWLIREASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S323</accession>
    <name>A0AAV4S323_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRP15-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RRP15</name>
        <name evidence="4" type="ORF">CEXT_554771</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008950">
        <property type="protein sequence ID" value="GIY28515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S323"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012459">
        <property type="entry name" value="Rrp15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245:SF14">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07890">
        <property type="entry name" value="Rrp15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY28515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="22749" checksum="AD7AD38DBBA05402" modified="2024-11-27" version="1">MEERIEIEDSDVEMGASDNASDNESDLSERNEDELNGNDVENFADESSDDDRETVKGNAGWADAIKSLVRRKKKQSKDKKLKEWESMCRVKPDIRNKDRERELIRIATGGVVQLFNSVEKHQKTLKTSKKKQKEKKLSVVKGNFMDILRECTKKEKTAEENPVVKKEKQEETWSILKDDFMMGANMKDWDKDEEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S384</accession>
    <name>A0AAV4S384_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_473211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008825">
        <property type="protein sequence ID" value="GIY27501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S384"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17094" checksum="07F45AC997D70631" modified="2024-11-27" version="1">MRYRLQGMFDSCPLQTFSLNYHSLPSTPCTTFPKCPGKVLRTTTSSFCDKKEDTQKDCPPLSGFRCFRTARSSLLNVQLNGRTHAPDILVTVAVHFPQVVSRKLRDVTTSTPLSFIALLFPGFQMLDKEWGGRGKKESPGMGRKSIPLTNPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SA59</accession>
    <name>A0AAV4SA59_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Receptor_IA-2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_202260_2</name>
        <name evidence="2" type="ORF">CEXT_355641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009112">
        <property type="protein sequence ID" value="GIY29687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SA59"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="199" mass="22975" checksum="009A7620D284BDFE" modified="2024-11-27" version="1">MAEAPLIRTELSSDLTQLPVFTEGGIEWLPVDDDDAGDMVDELIEPYDKKRVRMIHGKNNPMYKDKNGEDNDMNHVITLSGPEIERDENDLSKFNEEEEAPTFGQVARNSGEDDDSNFQWNPKHRNRFMDDDLTRFAKGNDVQSRTFHPKPKPSDNTELSDVIENDYLEDQLYAILPINKDIPTFTDKRYDTKKPDQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSK6</accession>
    <name>A0AAV4SSK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_561821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009988">
        <property type="protein sequence ID" value="GIY35979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12647" checksum="E6831A2F3E458E2D" modified="2024-11-27" version="1">MFGKKLRVLLVPTIVCCGTLSSGSILLWKEGLADEIFLKKKENVILPGMPNYQKPGVILGLIHDIYKSQSHDINPLNKHVMETTSKVYGDYLDTFEKFGIDHWQQLIVLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYA7</accession>
    <name>A0AAV4SYA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_359621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010293">
        <property type="protein sequence ID" value="GIY38354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16644" checksum="30DFEA318C71B555" modified="2024-11-27" version="1">MVMPGKHLVSTTTQNTRNPLSAERKPLYSEVCRTGKGEIKRPKQQKIEASTLGGDTKDVQEVYDLTYFPRRETQVCGLNYCPPKRDVAVNELTYCPPKRVWKGMDSLIVLRRETWKVMDSLVLRRETWKVMDSLIVLQRENGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TC94</accession>
    <name>A0AAV4TC94_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UPF0669 protein C6orf120 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RCJMB04_5l6</name>
        <name evidence="7" type="ORF">CEXT_379321</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0669 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010850">
        <property type="protein sequence ID" value="GIY42447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TC94"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031420">
        <property type="entry name" value="UPF0669"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31703">
        <property type="entry name" value="UPF0669 PROTEIN C6ORF120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31703:SF2">
        <property type="entry name" value="UPF0669 PROTEIN C6ORF120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17065">
        <property type="entry name" value="UPF0669"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY42447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="19281" checksum="5A13C410BEDA0081" modified="2024-11-27" version="1">MPVCQCTDHFQESILGAVGGGNYSYYWLPQPGTVILQLHTIEGDADLYVSSKNLKPTYDIENHDLQSTTCGSEQVQVPSYYERPVSIAVYGHPSHEISLYELKIDVYESIVEEEELYEDLSSDSSKKTHFNKPTAVPNIPAKDDPDYEERSVFWTLLLHILQVLLDLLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCH8</accession>
    <name>A0AAV4TCH8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_107231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010852">
        <property type="protein sequence ID" value="GIY42470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCH8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043539942" evidence="1">
        <location>
            <begin position="19"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11930" checksum="C53CEC4C849C37B7" modified="2024-11-27" version="1">MESLYGWVLNLIVKVASCLECGELSCEKQFPLELAHLQNVTDNSFCEVTLAAEVGSLMAFRKLKRIINRKNITKVWFEPTDLSRAMRPFQASSKWKSALAYASRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIZ0</accession>
    <name>A0AAV4TIZ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hephaestin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Heph</name>
        <name evidence="4" type="ORF">CEXT_168431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011272">
        <property type="protein sequence ID" value="GIY45426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIZ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04200">
        <property type="entry name" value="CuRO_2_ceruloplasmin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF504">
        <property type="entry name" value="PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="151"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY45426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="251" mass="28639" checksum="F3A51C5D4CC4ED81" modified="2024-11-27" version="1">MIRVVFKNMASRPYNIHPHGVLLSKFEVFNDAVGEDEEPVAPGETHIYEWPVPERAGPGRNGFNCSSWAYYSTVDSVKDTNAGLIGPLITCKPGTLTSKGYRRDMDHEFAVLFTIFDENRSWYIKENTYTYTQRPETVNPLDPGFILSNRMHAVNGRIYGSLEGLVARRNTLAAWYMLGMGTEVDMHTAHFHGQTFLRRTDSTRRSDVVYLFPGIFETVEMIMDNPGTWFLHCHVDDHMRAGMAATYTVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TP49</accession>
    <name>A0AAV4TP49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_184001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011474">
        <property type="protein sequence ID" value="GIY46742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TP49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="35" mass="4009" checksum="DFC091843363E38D" modified="2024-11-27" version="1" fragment="single">SRADRDSRSVRVSRGTAFAERENADKEDTKPLMRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQ07</accession>
    <name>A0AAV4TQ07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_52751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011571">
        <property type="protein sequence ID" value="GIY47392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQ07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY47392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11478" checksum="73D1BDE16CEA5150" modified="2024-11-27" version="1">MNHLLLQVPGNPTQCPTPTPPCLTSLFPQTANRGVLPGRQVLNNSIKYRTMAFFPSEIFRPKTCFLFRPFVKVRDQGHENRRRKRIRSRGERGKVSNQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRF8</accession>
    <name>A0AAV4TRF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_380751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011587">
        <property type="protein sequence ID" value="GIY47522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12395" checksum="B9C2374840204C49" modified="2024-11-27" version="1">MLFILFGDGLFEVSKDMRLPFARFHHYPRFVIKARREDILAHLVLCRCVKTNICLVDMHVLAYPANWLQSNRTEKMISNLSELCLTFWKVFGPCQLLSSCIIEIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TTV7</accession>
    <name>A0AAV4TTV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_32364_1</name>
        <name evidence="3" type="ORF">CEXT_604221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011818">
        <property type="protein sequence ID" value="GIY49304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TTV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY49304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18346" checksum="6DFB3401F195D76C" modified="2024-11-27" version="1">MLLLRYQRQRQAEAEEGGGMGRTPEHEMRRKISDRDLKGESHRAATRGTLICIFVCGSALLSLGLVVLFVGIYVPGLREDPTPWLVIGPTCIVLGILVLLLSVEIIVKLRKISASSSSSDSSWEKTPSKQSLMVQDPPRAIPVVVHPATPLHQLDAQALPLEVVQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZQ4</accession>
    <name>A0AAV4TZQ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_161191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011975">
        <property type="protein sequence ID" value="GIY50418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10719" checksum="2FF6BE71B502FEE9" modified="2024-11-27" version="1">MRLILNYESELQLGRNWGDVTTLLDFDNTLQLHLHGLVLHTAIFSNTAHSCPFGFTTLEVTGSLSKLADGTTKMIAIETLHSFMKEKLKCFEISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1M9</accession>
    <name>A0AAV4U1M9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PLC-beta PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_733651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012136">
        <property type="protein sequence ID" value="GIY51655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037862">
        <property type="entry name" value="PLC-beta_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17787">
        <property type="entry name" value="PH_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLC-beta PH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14210" checksum="3C7534BC01D519F1" modified="2024-11-27" version="1">MGTPDTPLEDKQVTVVYGPELVNVNTLHFSCNCKETAQKRTEAVHGDLLKTHYFPEGLPPTYKSMYEINNFYYGSYPTCLHKFYLKEDSNMRTCRKPITSSPYVLLPLSSSSKLDLASTCYFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5U0</accession>
    <name>A0AAV4U5U0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_29721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012326">
        <property type="protein sequence ID" value="GIY53139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5U0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8315" checksum="095F14A0EB07FEBF" modified="2024-11-27" version="1">MSMESWKGYYKSVSGNVFLFGSRGTVRSGCFEVHFMAYPEEREKSAPLLLLLSLAEINVFGHLNATTNSEGTLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6U8</accession>
    <name>A0AAV4U6U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_252921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012369">
        <property type="protein sequence ID" value="GIY53501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11179" checksum="9672624D963EA3BA" modified="2024-11-27" version="1">MPRYLLPYPLLRGNDGIIKRRKEVYGGGDSLNDYTRDLGVLGCSANDLFSSDRGTELEKTEGDRSSEIRKTKRMLCYSGTNLLWFPPEWSTSFFIHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7V2</accession>
    <name>A0AAV4U7V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_329231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012415">
        <property type="protein sequence ID" value="GIY53849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9901" checksum="1E46C56A19D1F1A6" modified="2024-11-27" version="1">MLGLSFLHGACTNSGYCISFNFGRYKWQRLDEAAECCCCCHEGAPDIRSAEGFTRQLRLAGGFRDIRVIKLNILVFLLKLIPGMLLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCG4</accession>
    <name>A0AAV4UCG4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_806491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012642">
        <property type="protein sequence ID" value="GIY55448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCG4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13323" checksum="E7FA322524FD0E24" modified="2024-11-27" version="1">MCFEWKQPNSRASFSPNPKMKATSGTDCRHQITKCSEEPPSSRQILKNISQMFYIFAVLSAINQEMIYSGVILSSRNTLLIKEWGKRISRNNMMNTTLCALNGNNPIQEPVSHQTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULL3</accession>
    <name>A0AAV4ULL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_135081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013082">
        <property type="protein sequence ID" value="GIY58604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11573" checksum="7E78AE66F807CCFD" modified="2024-11-27" version="1">MQFSFSQAAAAPEIYFYDYFLSLIPPRSLMPTSPSRLQSQREVFHQSVVAICGRGREKILVAGRCAGMHVSITSGEGEKLFIPQFFVAEEREELHRNLLPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4USW0</accession>
    <name>A0AAV4USW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_718531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013375">
        <property type="protein sequence ID" value="GIY60755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4USW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14384" checksum="376117AC8F1D4C19" modified="2024-11-27" version="1">MFAAVQARLDKKPSHYHEKAAAFFEAEAVDRNLRRFAHSCDTIFMTLMTAYFHCVGNFYAVVFQRLNIADQATTPLDELAPIPEQQVHMEDMLRSLHERKRKKEGIQRRSSWTTTAIEPWKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UXX6</accession>
    <name>A0AAV4UXX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_107859_1</name>
        <name evidence="3" type="ORF">CEXT_195381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013664">
        <property type="protein sequence ID" value="GIY62762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UXX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY62762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="24105" checksum="4D676BB391027743" modified="2024-11-27" version="1" fragment="single">MAASTVLPTYQRYINGAPVSAAGRKTLRLREKYIVLLVLGTFVAVCIGTFFFLPEFRSGSINNAYRHIRNAGSDLLLPPLQVVDKALLQPHDVNNADPHVIMDRAKLILKIQEDLEQERQKNLKENMDKAQVENPLSKTDHQNADKMKELSKGKDDGILAQDQLVNDVAQIPITIGRNDPGASELNDIVRDHPGGPGTRGGEPSDPDIREKRNKIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5W4</accession>
    <name>A0AAV4V5W4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_793161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013982">
        <property type="protein sequence ID" value="GIY65330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5W4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10547" checksum="2E1649A126CEFE0E" modified="2024-11-27" version="1">MWILNKDNRNLCIRLVTVYPVLRQAPLTKSKCVFNGQLRTWEFKLIKRRLVVIMIDLELRCLFTVLNTMREKLIRRCCTLILPILGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7Z2</accession>
    <name>A0AAV4V7Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_683181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014109">
        <property type="protein sequence ID" value="GIY66355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="14859" checksum="E10875864069289C" modified="2024-11-27" version="1">MSSQYRYQYQYRLTSVTFSQIWQVFPETHHHVQASWLPQPQVPRQADLGLHALSGCRRRPGQELPHAQAHDPGGAVLQAVDLRPHGGLPQDPDGPDARGLQQRQDAADPGLHPGEPGAGEGGAPHAAELFRNTSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8S6</accession>
    <name>A0AAV4V8S6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sodium/calcium exchanger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SLC8A3_0</name>
        <name evidence="3" type="ORF">CEXT_654701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014143">
        <property type="protein sequence ID" value="GIY66682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8S6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098794">
        <property type="term" value="C:postsynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005432">
        <property type="term" value="F:calcium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051171">
        <property type="entry name" value="CaCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032452">
        <property type="entry name" value="Na_Ca_Ex_C-exten"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878:SF65">
        <property type="entry name" value="NA_CA-EXCHANGE PROTEIN, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878">
        <property type="entry name" value="SODIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16494">
        <property type="entry name" value="Na_Ca_ex_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sodium/calcium exchanger" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY66682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14284" checksum="22C0C3F2CB02FD9B" modified="2024-11-27" version="1">MAREEILEKGPKSRAFYRLQATKKLTGGGNLLKKKLEKPEPEKEESKETIRDDVCRIYFNPAHYTVMESVGQFAVTIVRSGDISALCVLTLRQKMAQRKPDLTTNHWQGLLSSVRRSSTASLHNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9C1</accession>
    <name>A0AAV4V9C1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_285131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014130">
        <property type="protein sequence ID" value="GIY66541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9C1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11599" checksum="73CA62D0E7EC4322" modified="2024-11-27" version="1">MAHRLCTYQCAGLPIAIAVMDMSCATFLFHGQYRAAQLGEPMSSHGVDRDSGFSSPIGSHMTMSSGAHNRYTCWFSLVVQPALAARLLLHTLRENNKDLSTSDKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V9K7</accession>
    <name>A0AAV4V9K7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pleckstrin homology domain-containing family F member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PLEKHF2</name>
        <name evidence="8" type="ORF">CEXT_422561</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014144">
        <property type="protein sequence ID" value="GIY66703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V9K7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15717">
        <property type="entry name" value="FYVE_PKHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01218">
        <property type="entry name" value="PH_Phafin2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000167">
        <property type="entry name" value="Pleckstrin homology domain-containing family F member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051765">
        <property type="entry name" value="PH_domain-containing_F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037871">
        <property type="entry name" value="PH_Phafin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055251">
        <property type="entry name" value="SOS1_NGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46280:SF3">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46280">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22697">
        <property type="entry name" value="SOS1_NGEF_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="35"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="152"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY66703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="332" mass="36233" checksum="E5261D31DED771A3" modified="2024-11-27" version="1">MVDRLVNSEANARRIATVENCFGANGQPLAIPGRVLVGEGVVTKMCRKKPKTRQFFLFNDILVYGNIVMDKKKYNKQHIIPLEEVKLENLEDDGILKNGWLIRTPTKSFAVYAATATEKTEWMAHINKCVEDLLKKTGKKPSLEHAAVWIPDAEASICMHCRKTQFTVLNRRHHCRKCGAVVCNPCSSKKFLLPAQSSKPLRVCLSCYDTLTKARANQDESTVSAKLNIPPSNQDSSGEDDSEDENDDGGKIGNLDKGLDNISIDEKPTFYGDTAEAPSDNSQQTPCSSDQPTSSDTCASNTCSDSVATCSDSAYDAGSCDTSTCDAGTSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDL8</accession>
    <name>A0AAV4VDL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_365801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014275">
        <property type="protein sequence ID" value="GIY67714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="20722" checksum="0D6B131CAF8763AC" modified="2024-11-27" version="1">MPQIDKHISSCDAIRKDLLTGQVKEHKVPENKSTPELIEKFCIQKFPLLESKENEDASPEEIRSKLRWPLEVQALESMPRLLHHNSYSCSYGRNNIMIISYTKTALDKSNFYLDETFLKATSRHSKFDYRIDMMTSKNTFGTNRSPCGTLSPLKADLCSQLIRSDIFVLNCPRYLEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEM1</accession>
    <name>A0AAV4VEM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_272881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014449">
        <property type="protein sequence ID" value="GIY68826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="10292" checksum="D009C27340425407" modified="2024-11-27" version="1">MSGLLEKEIKLLEQRPFELERDCFGKNGTAVLGQKRKRNKFRIFGKFETREILINSWEDFEKQHRNFKPTSYFCFAFIREYIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFF8</accession>
    <name>A0AAV4VFF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_141571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014358">
        <property type="protein sequence ID" value="GIY68283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="11010" checksum="801F2CCAC081E184" modified="2024-11-27" version="1">MRTYKEHLLWLKLRKTAQKKNISFPDEKLLLVKVWHSSVTLTKHDRLTELELFSPTLVLQGGREHWIPNPVSRQRSRTHEELREGGQTEPLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFM8</accession>
    <name>A0AAV4VFM8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_95601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014463">
        <property type="protein sequence ID" value="GIY68918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9544" checksum="88E25ED90176D8D4" modified="2024-11-27" version="1">MDISLLCLSEPMYPLTLAYFGVDPFEKKATTVIYFGFTKIRRYFWNSQMVLFSFVIKVRQRESGGQRATVSRSSPSIKPSSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VG52</accession>
    <name>A0AAV4VG52_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Outer dynein arm-docking complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tetratricopeptide repeat protein 25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ttc25_2</name>
        <name evidence="9" type="ORF">CEXT_45541</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014511">
        <property type="protein sequence ID" value="GIY69272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VG52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040111">
        <property type="entry name" value="ODAD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY69272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="208" mass="24112" checksum="401A742ABE9F3B1D" modified="2024-11-27" version="1">MFITEGMGYLKLRLFNKAMQCFNTALEREPTNEASLIGRAKCYMNQGLYLEAKEDAEAVLKVHPKSPMAKVIKAEIEYFLGDFERSFLTYAQAYNARPNYDAFRLGFQVCENSIENALKPREGLHLDENDIEGIEKLLGGGPSKDADIKEPDSSKKCNVYEDDIKFLNDRLSDKFIEFLHPQCKDLKEFLEGRQEFWNYEKPKVTKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VHK4</accession>
    <name>A0AAV4VHK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_703871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014586">
        <property type="protein sequence ID" value="GIY69797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VHK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11156" checksum="2F45D2D4D1311132" modified="2024-11-27" version="1">MNEHSKIHVDRWKDCLPAYVGMVCGLLKSVSRASFSENKWESCPAIYLVWTLRGAGLDMIYNTFLFRGYQESCRAIYFVWTLRGAWMDMIYNPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VN04</accession>
    <name>A0AAV4VN04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_45361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014739">
        <property type="protein sequence ID" value="GIY70984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VN04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9524" checksum="21093BB383DEC8DC" modified="2024-11-27" version="1">MTLPQFGNNSPGRVIRGLTPSTHLFKPVRQTLRPTNIYESISGDYSDHPDQRRICIARSTVQATTFKGHEHLGPKVLARLQNSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPD7</accession>
    <name>A0AAV4VPD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_647041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014910">
        <property type="protein sequence ID" value="GIY72182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14350" checksum="E9848CBD3D1038CF" modified="2024-11-27" version="1">MVFQIGLLLSKLFRCGRQRDLIAIRGMIGFAADWFKDIDVKMILFYSRLTELLVYGKSVLSTGVWANRNTNRQKGTPAPLHWEAWTIPSAVCQRSSVHPEKMDKRLSITGRNECPLSKNAVNDGALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUF6</accession>
    <name>A0AAV4VUF6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c biogenesis B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015139">
        <property type="protein sequence ID" value="GIY73901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUF6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19255" checksum="0CB7B6D9C09CF8A4" modified="2024-11-27" version="1">MNIFLVLFWEEDRRKGIPVPFHLMSVMQGSSQTSLAIDPIQEFLGYRSIPSVLWLSTPSKVLWLSFSKCPSAITSSRVSWLSTSNCSLAIDSFKCSLVIDSSNCSSAITPLRVPWLSSSKCYPSKILQLSPLQGFIGYPPSKSSSAVILSQVLFGYPPQVFFGYHPLKISLVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VXZ3</accession>
    <name>A0AAV4VXZ3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vomeronasal type-1 receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_353231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015232">
        <property type="protein sequence ID" value="GIY74579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VXZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16892" checksum="CCCC1B3C9C93BADA" modified="2024-11-27" version="1">MSRLADYFVVVGFDHDKERSGLSSGKVLQRFPRKIGMIHLLLMVLNYFVSLRAGICQPFVSSQHILYQYSQISMLIVTTVHAFPSTNLLLSHLANHLMKKVKRKRWSPLGAGTASFHYVCSKMSSFSFKARLLFYFSKLPRNHLHCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0N8</accession>
    <name>A0AAV4W0N8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_377101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015450">
        <property type="protein sequence ID" value="GIY76217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0N8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY76217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11746" checksum="04CA2A2EC4145BC7" modified="2024-11-27" version="1">MLMDDRVPSSVVSGEDEMLLKGGQRIWPIKEFAWLNVTLIRKEKSEDQIVFIGIIFNITNLILFLNNRNLRIYTFSSFGEQNPETPIGLNVHITTTIDFPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W3L0</accession>
    <name>A0AAV4W3L0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Plexin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Plxdc1</name>
        <name evidence="9" type="ORF">CEXT_282961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015505">
        <property type="protein sequence ID" value="GIY76625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W3L0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002165">
        <property type="entry name" value="Plexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031152">
        <property type="entry name" value="PLXDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13055:SF12">
        <property type="entry name" value="LD40707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13055">
        <property type="entry name" value="TUMOR ENDOTHELIAL MARKER 7 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01437">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="449"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY76625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="557" mass="62307" checksum="13A5D5B2ED14D852" modified="2024-11-27" version="1">MAAALQLLGFISIVYSVQIFNYALAYDSVGYSHFNPSIDLKVHQVDGRYLENEDLIKTSYHVYKRSVLIPPIKKATSLVEKKIPTKTVSTESSVQLKTFAAESKSKEENSTLPLNGTEIDLSVATTITNSSNTTISTTSTVATTFSDVLPTKPSSINDPKVDHHVYYNSTLLLENEKALAYWVDFEKLPKDKVIIHRMLSDSHRKAATVRLSFDFPFYGHPLRNITIATGGFVYMGDYMHSWLAATQYIAPLMANFDTSLSSESTVQYFDNGTAFVIEWHNVTLQDEKKGGNFTFQTTLLNNGDIVFVYKEIPISVTEIGDEAHPVKVGLSDAYVIDRILYFIRRKTIYEYHRIDMKNAVIGNNTAIYFNALTTCMTFQDCKSCFEANIGSHCVWCEAAKRCSDGLDRNRQEWLQLKCDIEEEAENCSAYSPNNPDPYVQSLTDSPYKPYALSPPTPKSDHPFETSSIPHMPYKPGQMSDDGASTSARVAEESSSMGVGSVIAVLLILAMVMGGLVWVGYAYKNPHTSSGQLLIRYRPSQWRFRSGEARYTAASVHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFP1</accession>
    <name>A0AAV4WFP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_19444_2</name>
        <name evidence="2" type="ORF">CEXT_222241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016150">
        <property type="protein sequence ID" value="GIY81640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="246" mass="28800" checksum="D4518872985416F7" modified="2024-11-27" version="1">MIQKRGIRLPRRSMRLKRQVDMEDLINLFGNDRFYDEEAQIPGRFSGYPETPAPEYRYPYVFQHRDLGILNPGNEMEDNTEALEGDNMEDVDNLMLMPPIPDMRKWKDMGMSRGDDEKEAIQSWLNRHTVPSVFRVSRRSAPYFYPIDYRYIPGYKKRSRLFSNGNRDLGRFSGDEEPERASSVSGATSCRFPRPTLLPRMWPGSTAWPASWPKRRSRRSEFAEQPKPFLPNDIPMLCSMRGGFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGA4</accession>
    <name>A0AAV4WGA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Homeobox domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_135431_1</name>
        <name evidence="1" type="ORF">CEXT_776601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016143">
        <property type="protein sequence ID" value="GIY81566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="23004" checksum="022EEE80924B89AB" modified="2024-11-27" version="1">MVERGRGEGWRAKREFLCANFVRSSSDKGTKSRAFHGLIPQAGVWFQNRRSKERRMKQLSSMGARRHFFRSPRRAMRPLRPGMSPDGLDDSPDMVSGPNSGYTYFSAHMTCQTQTSCRFFFLVASRKSIATHSENRHSCDQRTNDKTVVRAVNYGCRSFTHRDPDKRKQLTYSSSPVCKKSHPRHCLFKWKGYLFRHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WIF8</accession>
    <name>A0AAV4WIF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_589651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016197">
        <property type="protein sequence ID" value="GIY82014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WIF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11168" checksum="760B200DEF24FE4A" modified="2024-11-27" version="1">MKDSSLSLPNSRHVFQIPPPPLVLRSSLPRSEIGKLVLIGLTNYSYGSGHGVTDEPLANFGIGNLPQQAIWRFFSISDFCINKMDEKETNGVAMTFTNSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WJB5</accession>
    <name>A0AAV4WJB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_92531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016186">
        <property type="protein sequence ID" value="GIY81959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WJB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12247" checksum="6ECBE099AEFC6DEA" modified="2024-11-27" version="1">MNMIIINFDTRSIREKKKKKPNDFEGPFCAGIVCETSATCRTGGGGEFFQPMEESGRAHTAEDGTDGGRGFDAHVLRIRNRPLLPPTAPSRRTRRCFPKDPPLNFRPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WTT5</accession>
    <name>A0AAV4WTT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_625921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016685">
        <property type="protein sequence ID" value="GIY85738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WTT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY85738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12762" checksum="CCB84D1D9D85BEBC" modified="2024-11-27" version="1">MVVTPERRENGEREKMKIREKKERENRRLLARSPLFLQSNPLSSHPQKFFTSTRNSFVCLRDAVSIDFLLCISLKRLCEANVVSYCRDKGKKKREEKAVFAKRMATRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WV42</accession>
    <name>A0AAV4WV42_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_52761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016748">
        <property type="protein sequence ID" value="GIY86153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WV42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043562594" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7640" checksum="C49CF52490560464" modified="2024-11-27" version="1">MVWRLASSSSFLMLLDVQLANALAFGNRFGILISMNLQIFYMKRSMLRHNPPRSHQFDYTSIRSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXE4</accession>
    <name>A0AAV4WXE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_767011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016760">
        <property type="protein sequence ID" value="GIY86193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9531" checksum="CBB046B1FC0693AD" modified="2024-11-27" version="1">MRTVETFCEIFVKPFVSCEIVTGVDNHLQLMQKKKRHIHFPTRNARSHFKKQIKNCSKTLRWEVLLQTPCYPDMNPFGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8C6</accession>
    <name>A0AAV4X8C6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_512131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017412">
        <property type="protein sequence ID" value="GIY91417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8C6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="22070" checksum="F2140043027649E6" modified="2024-11-27" version="1" fragment="single">MLTAELIYSSVFQRHRHPRTLSDFELGISSLSSCPTTSSTTSPPARPDVHPVWSKNRSRMLEKEGVNFRAKRRRVDLAPPQMMMDRAPGSGESSEGCYSPSLPSTRNCSRSLPSTRISSPSLPPSRSSPVCCGSPPTGAAIQRSPASPTSSTRRTTRLGRFHPYSKPESPALPPQIARSPPPPARSPPITRSQTGSLPLRTSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9S2</accession>
    <name>A0AAV4X9S2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000066">
        <property type="protein sequence ID" value="GIY91897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9S2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10393" checksum="4BAB38ABFCEE3888" modified="2024-11-27" version="1">METYCEACTRGKDDVFILYPPIKALVFVLVFSFRCGRETEQSGDERTRKMANIPFLLGSFGDSSSNNSVSNAHFFFSLLILRHGKECCKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK51</accession>
    <name>A0AAV4XK51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_360661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017756">
        <property type="protein sequence ID" value="GIY94189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9244" checksum="47741C5DAEEDC98D" modified="2024-11-27" version="1">MDPIKLHQQWSQLISINKVANESPSNNGANQYSSNNGSNQSPSSNEANYSPSSNLATHFPSSNGANQSSIYIKQCNQSISIKQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2J5</accession>
    <name>A0AAV4Y2J5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_483231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001336">
        <property type="protein sequence ID" value="GIZ01696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2J5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17422" checksum="A87F158561ADEF77" modified="2024-11-27" version="1">MTVERQTKPARRGFHKTNAKHTIVDVCRCLHTQTQSPSGLSKSKSVLLSLSVSGSFLWATVGPQRRSANEALRRVREDLKYLTGPVITSRKSRTRYRGTRLCHQWPRLSHRFVTFRPQDSFSRTRAPFLHKAQTKKEKKAVFLFTFSIAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y323</accession>
    <name>A0AAV4Y323_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_94551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018534">
        <property type="protein sequence ID" value="GIZ00381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y323"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16074" checksum="C7A9D8DA911A21FB" modified="2024-11-27" version="1">MSTFFKNFVSELDRIALTTTDSRTGWQLSENSNFFFAADVAAHQLLLRAAPRRTPRQTPGHPAALREGHRPLRPEGAGLRGHAGQAAQADEGRQQRRQSPFSFVISILKLRPRLEENGRTKTNLFSEGLDAALNACVSVFSGRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y390</accession>
    <name>A0AAV4Y390_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_605661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018694">
        <property type="protein sequence ID" value="GIZ01623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y390"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10732" checksum="27FC48F628480DC9" modified="2024-11-27" version="1">MVLPEDRLPRRRRVACKVCRIHSWCSQGSSSAWIKSSDHWGGRAYTCRWEARCRGHLGCPPAQKSHLIRLEYSSKTPMADNWFIYIKINQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y393</accession>
    <name>A0AAV4Y393_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_503951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001342">
        <property type="protein sequence ID" value="GIZ01722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y393"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7922" checksum="D6A67F935D92E1FC" modified="2024-11-27" version="1">MGILSLISVISASTKLLEAETKTFLLKSNFRLKIFPVQRRRSHKIPDKTLQKKTTTSQPGALHFSELVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3F3</accession>
    <name>A0AAV4Y3F3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_171341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018733">
        <property type="protein sequence ID" value="GIZ01873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3F3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="27092" checksum="A9607E281933E3C2" modified="2024-11-27" version="1">MNIAVLSQFNHNNNWALKIEISLAILLLKSSKVFFNIEYVNILKNEHFFQASHGRKRKALRFLPAAQEREMQNPGLTQLDPRLFMNTGTPITEEPTAIMDNRTKHLDVKRACFFKQIKATEPGKTAVHASSGGMKSSKIKLYFPSATNLYQRRKFRLRSIKKVMQRSSGVSFDIRAQTEAPIFPTQQKPSCGKGINYCCVPINQWLLQWAVGRSQKNQSSKKNSYDVSASILDVWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5X9</accession>
    <name>A0AAV4Y5X9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_25611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001458">
        <property type="protein sequence ID" value="GIZ02438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7517" checksum="DC5935982E73BCD8" modified="2024-11-27" version="1">MYALRIRKQNTPEIGRRLAFSQDKSDAWTKTLSPTLTTPPAKISPPLLARQHTPPRAECVTWETEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6H8</accession>
    <name>A0AAV4Y6H8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001347">
        <property type="protein sequence ID" value="GIZ01764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6H8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15439" checksum="B0ADA9700F0FE6F8" modified="2024-11-27" version="1">MSNVRSILVCQETPQKPSRLTVCLSSHRWNFSGILANAIAKGHNNGGKSSHVGHKKKERVVVHLRFVYEWGESIRLCRDRSSLRRPDRYSKVKRILCEEAKHLERSWFLSCVIALFHCDTIHKIFLYFNMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y701</accession>
    <name>A0AAV4Y701_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_572681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018861">
        <property type="protein sequence ID" value="GIZ02790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y701"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="11007" checksum="1AB20BA370C5D1F5" modified="2024-11-27" version="1">MVFERFVRIQAPIQEIIHKHHNENVPFKSNVTFHSARPYARSPQIFVQWSRIYMPKYESDFVSHVRKKNPSYHQNIKHYKQQITSTSQLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7P5</accession>
    <name>A0AAV4Y7P5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_224091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018767">
        <property type="protein sequence ID" value="GIZ02167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7P5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8935" checksum="D1A11EC6109222A2" modified="2024-11-27" version="1">MKSLLLRGTYQPNGNAPTEAAYVLSAVRVIAQLLRHSVRCLLRGTPLKLSSGNNGTGQEEKLPYNMRRLLDQIKHRDCDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y917</accession>
    <name>A0AAV4Y917_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_645771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019001">
        <property type="protein sequence ID" value="GIZ03838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y917"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13993" checksum="E28F121FF0536B67" modified="2024-11-27" version="1">MCSLLKILSNIPYRMTTTPLMVPIFHFVCSTSTHEIIPRISYFTPQPFPPTQISITVARTPLLKTFDRPPSKKTNPPSIAADIALNKAAHDLMKATYRLVHNTDSEHNILKRPLFLADGRCGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YD39</accession>
    <name>A0AAV4YD39_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_446151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001732">
        <property type="protein sequence ID" value="GIZ04409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YD39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14594" checksum="0407460E64E43688" modified="2024-11-27" version="1">MPVVSLLLSTGALLSNTSIPKVEENILYPFAHLILFGNFCSFHSVLFGRGGDERRSACTRAKDKRELSAFQKSNLIPTRNLTGDDKRQKTKLQFTSLTSFLSFFFVPFRSLITSREAFTVFPTLFVCFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAL3</accession>
    <name>A0AAV4MAL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_198301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019491">
        <property type="protein sequence ID" value="GIX68456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9629" checksum="B940B2B784AB365F" modified="2024-11-27" version="1">MIFPPSIRRTSPGVHLRKAKVVETPNRRAASPAAVQRLRRRAETIRANFTPPQPACFPFRFSGSPPAARLSRLDQTPGVFATFRGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDP6</accession>
    <name>A0AAV4MDP6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_673211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019621">
        <property type="protein sequence ID" value="GIX69807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10463" checksum="1791E1ECE9E11E6A" modified="2024-11-27" version="1">MYVNTDSRDSQYLSRYSISPKKEPTHSWLGEQLSELFPHSLTLSGRGTSPTFPSKTRHFWELTIVARLSSARYWLDPKRKQTSQESERAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEZ1</accession>
    <name>A0AAV4MEZ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_297251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019701">
        <property type="protein sequence ID" value="GIX70855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043910076" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10460" checksum="13CB48122C2C0C4E" modified="2024-11-27" version="1">MILMLFQLLSVMDGLTGVVQKLSAEECLEVGYPYILPTLSSAAVCPQLPLLSSPNTAEAAVTAQSSSILIHRVVTCHRLFFITVCLPMHASSKTKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIU7</accession>
    <name>A0AAV4MIU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_785571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002280">
        <property type="protein sequence ID" value="GIX72107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9473" checksum="CC9D4667507F027F" modified="2024-11-27" version="1">MSLRTIFKAARQILPQSQRQREESAGNKTHPLRLNYCRASFCRSQSPLESSRGSIRPPPYLPPLEKYCWRNRPWGDTGERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNE5</accession>
    <name>A0AAV4MNE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_811881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019955">
        <property type="protein sequence ID" value="GIX73474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10739" checksum="38E5A431BA25EE23" modified="2024-11-27" version="1">MIIITDATKFQGEVILFRYYKPPFVYFADCPIRRASAFGNALPFHPPTIRDDPIEFHPGPFVLRNSKSIPELPERFEIAQSGCQKFVFNPFCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQP4</accession>
    <name>A0AAV4MQP4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_204691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020089">
        <property type="protein sequence ID" value="GIX74693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQP4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11047" checksum="2E4699A52111C6FC" modified="2024-11-27" version="1">MAILYQYIYDDIIAKQFQNCFSFEIPSPILHAAWRIPALTTNKLPTVAIFRFPFREILNGAWITNGPHPEPYQFSSMPHFGGSCPVAVLEDYPEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MR35</accession>
    <name>A0AAV4MR35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucose transporter type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Glut1_2</name>
        <name evidence="6" type="ORF">CEXT_578561</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002506">
        <property type="protein sequence ID" value="GIX74481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MR35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX74481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17254" checksum="B2A93266C324DE67" modified="2024-11-27" version="1">MIEEERIFIDKDLTSKLIFATVAAAFGSGFQHGYNTGVVNAPQSDNIYSKRSASEPYLKDTIQQTQSSQLWKIRHNLNLENNAKFGDEAQQIQNFINETYSEKYNKIPTASIVTIIFSLKVSVYCLGGMIGSLGTAYLAARFGPKGGLLLNNFLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSH0</accession>
    <name>A0AAV4MSH0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_400791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020152">
        <property type="protein sequence ID" value="GIX75248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000702">
        <property type="entry name" value="Transcription factor E4F1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000557">
        <property type="entry name" value="zinc finger and SCAN domain-containing protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX75248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="261" mass="29927" checksum="98A800A64918DCF8" modified="2024-11-27" version="1">MNQNPQFCEAWNPNPSVNTPLPAAEPCSLPGFQQTFGQRNPLMNQLDQPLNTSSQMQCSGIYHMDEIPSHFVSNFNERDIASTNHNETSQHNETSLGTRIFAVQTAQYNPMDPIPTTNEISPIHSKKCLKEFLPKDNQEPQNRSRGHARPYACKYCDKTFSYSCSLTRHIRTHTGEKPYKCTVCNRCFTNNFDLTNHMRVHTGEKPYNCKQCGKCFAQSSTLCRHFSTVHTDVKPYKCTECGKCYAVRSRLKRHMLLHNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MT82</accession>
    <name>A0AAV4MT82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_141591</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020086">
        <property type="protein sequence ID" value="GIX74652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MT82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="11" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX74652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9125" checksum="1E83AE8E6A761DD6" modified="2024-11-27" version="1">MGADIEARVNTTTTLQHGTALHIVAMQNHLEIAKLLIEYGANVYAKNAQNKLPADLLPQKEGNLFELLIQSAAQPVMLKDLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N1T2</accession>
    <name>A0AAV4N1T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_390081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002765">
        <property type="protein sequence ID" value="GIX77547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N1T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22931" checksum="1F6BC59C4DCD3704" modified="2024-11-27" version="1">MVKAMRVFLRNQVIPTLQQRACLDRTIFMQGGIPSHIAKLVMQLLKRGQTAHFAELKARITQHIKNETSLRHSCLLWNMVFPKNVHCADSVCFPIEYGVISEQHKLRNSHLRHFVADTTVRNALVQDDHWRLVTEPFADEKRARTRLSKYPVRQRNALLATAMGLVTATTNTLSSITIERVNPGWISLLLLFKGPSLHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N737</accession>
    <name>A0AAV4N737_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_108001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002954">
        <property type="protein sequence ID" value="GIX79610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N737"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="22128" checksum="7CC35E1871055A56" modified="2024-11-27" version="1">MYPDGLQIFQNVLDAAVMRLLTLQKKNMMLLLNLMKSNLIVPDDDDTRKFAMVETGLSSVQETECCCNELIASKKAADLLLYRFTSLFMWPYMLMSVGLLKEQDKLCFKTMPNLRPNIPKYQPSKNTKGCSPQKRKRCQTNTDAANKRIAAEMNKSPVRNPSIRRPSLNSPTSQLLRRSRRQCVLKRQQFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBB9</accession>
    <name>A0AAV4NBB9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">BET1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Golgi vesicular membrane-trafficking protein p18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">CEXT_213361</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="15">Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with SNARE complex members GOSR2, SEC22B and STX5. Interacts with LMAN1/ERGIC53. Interacts with STX17.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endomembrane system</location>
            <topology evidence="14">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Golgi apparatus</location>
            <location evidence="12">cis-Golgi network membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the BET1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003148">
        <property type="protein sequence ID" value="GIX81615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBB9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000026">
        <property type="entry name" value="BET1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056173">
        <property type="entry name" value="Sec20_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03908">
        <property type="entry name" value="Sec20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 20" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="21">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00054011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00063965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00071590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00077825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="GIX81615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12593" checksum="14793316DEB14781" modified="2024-11-27" version="1">MRRSHATESYSSFNRNTVEEENEHLVDDLETKITALKSLTIDIGHEVRTQNQMLREMDDDFDSTGGFLSTTMGRVLKLSKAGHNHYILYLLLFSLFVFFVIYLLLKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDK9</accession>
    <name>A0AAV4NDK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_52621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020818">
        <property type="protein sequence ID" value="GIX82912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11156" checksum="7A31BC04A9887910" modified="2024-11-27" version="1">MHYDPDIIDLAANQKGEITGSFSYSLKSSNSLHAFIFSRPQLKLHVFRSEVNLKEINTTSKSQSKRKNFHFKKKILSSSRGAFLFHLYPEVRVSRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NER7</accession>
    <name>A0AAV4NER7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_325331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020727">
        <property type="protein sequence ID" value="GIX81914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NER7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11317" checksum="81C8023340D1170F" modified="2024-11-27" version="1">MSLPFTKLHSRSFLPFGVVINLSWQTDPHTAANNRFQCLINPTPRHNFMPGFFTALLFCGPGLVNYGDGLSLRLAVFNRAYVNKRRLLSSYHISDFPSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NF11</accession>
    <name>A0AAV4NF11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_251381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020824">
        <property type="protein sequence ID" value="GIX82954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NF11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="516" mass="58374" checksum="0AA64192503397C0" modified="2024-11-27" version="1">MTDKQYLEYSKKLQVSFCPKEEGSEIFCEWLLVDNVTHLRPTPLALDMICFLARETVAEISKNGNWCSLWKPSSSHFNNMASDPKLRNFLSLTFQVNNMASDPELRNFLSLTSSSHFNNMASDPKLRNFLSLTSSSQFNNMASALKLRNFLSLTSSSQFNNMTSDPKLRNFLSLTSSSHFNNMTSDPKLRNFLSLTSSSHFNNMASDPKLRNFLSLTSSSHFNNMASDPKLRNFLSLTCSSHFNYMVSDPKLRNFLSLTSSSHFNNMASDPKLRNFLSLTCSSHFNNMASDPKLRNFLSLTSSSHFNNMASDPELRNFLSLTSSSHFNNMASDPKLRNFLSLTCSSHFNNMASALKLRNFLSLTSSSQFNNMASDPKLRNFLSLTSSSHFNNMTSDPKLRNFLSLTSSSHLNNMASDPKLRNFLSLTSSSHFNNMASDPKLRNFLSLTCSSHFNNMVSDPKLRNFLSLTSSSHFNNMASDPKLRNFLSLTCSSHFNNMASDPKIEEFSKPDFFKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NL54</accession>
    <name>A0AAV4NL54_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gag-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_620901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003438">
        <property type="protein sequence ID" value="GIX84558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NL54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX84558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="46534" checksum="E976E1745CCC8E0D" modified="2024-11-27" version="1">MATPVRHATPEKMIDFAENVTTLLTVARTIEGIFAKDKSTHKPTKTAVQQEFLKLDTLFCDKDKVIKQLRMEIDMLQQKEKEHKESIENLKEKDRQIAMLKGQLEESRTINREILTDNLKAITEAINTTKQVQTAPTKTFAEAVKKQQTTIILAPKDKDQSVKDMRSNISKQLKKSEELDGVKRVLIDNNQLIIKTKTDEQAQKLQESIEKNTELKEFLTVRTPPEQKAKIICYGIPEGTTEQDLIDSIDRVLELETKDTKLVKTFTDNNNRTHAIILLLKREAIQLLRRGRIFLDLQSCIVKPFYELKRCYKCQQIDHTSLQCKNNTTCGKCGESHDTRTCKKESKQCINCQNSNKTQKTTFSTDHYAFDNKCNIYRKTLNSLRDSTRPAKSNNTQQKQPLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NMQ8</accession>
    <name>A0AAV4NMQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_331531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021112">
        <property type="protein sequence ID" value="GIX86087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NMQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11385" checksum="63D4F98144C57C3E" modified="2024-11-27" version="1">MTSGRLFETYENNRLHSCLCFCRVYHLRITPASDYRFCRPSSASSTSSIPHLPVKSGLGSSATPSGRIGPGSKNSSSNNNSNSMLDKLKLFNPKDKSSERKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNG5</accession>
    <name>A0AAV4NNG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_759031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021046">
        <property type="protein sequence ID" value="GIX85310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17738" checksum="FD4EFB75579F760F" modified="2024-11-27" version="1">MLETIREYITDLHSSICTFVRDILTVGLLSQRPRQLKILTISNSLSVMKNFRKSKKCNDEGSRAIAFLITKTDGSDNLDFVKVPPETCLSKERYLVICAYRASMRVMYIYVIVLRLRMLSMSEHVVKDTLLNLKISIQILAFKNQLRLLFIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPU4</accession>
    <name>A0AAV4NPU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_624451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021172">
        <property type="protein sequence ID" value="GIX86814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14494" checksum="13D26FAAF09B4961" modified="2024-11-27" version="1">MGKWVDEEGGCVGGSDDGGSGSLSGNVCFQIAFHSVSNSRSSVFELDESTRGFCRLSVMLEAKKRRAFKNKVHSETLKDLGCVGGSGDGRFESLSGNVCFKIAFHSVPNSRSSVFELHESTRGFCRLSVMLEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NT18</accession>
    <name>A0AAV4NT18_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_484181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021276">
        <property type="protein sequence ID" value="GIX87916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NT18"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9970" checksum="62B2583097C9A4C6" modified="2024-11-27" version="1">MICSCISDTGHLCNAKDTGRLYVVDGVMQQDQCKHVLHNKRDIPMSSSCSTYVCYAIWSRLSYNRTVKAFYKKQSLYYLILEIHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWJ8</accession>
    <name>A0AAV4NWJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPCS</name>
        <name evidence="3" type="ORF">CEXT_581411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003846">
        <property type="protein sequence ID" value="GIX89282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="2">
        <location>
            <begin position="159"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX89282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="309" mass="35367" checksum="407758C3456E9B5F" modified="2024-11-27" version="1">MSDKEWKKFYEENPPPKGLLEIKTQISNFLFSNQLLFLSGGTSVPLEHSTVRFVDNFSAGTRGATSAEYFLRAGYAVIFMHREKTLEPFFRHVTPSKLFESSVPYKNNDGTHSIKVEGSVCDDLVPLLNEYKQIKEKKMLLKIQFTTLSSYLHMLYIASQAMRPMGKDAILYLAAAVSDFYIPERDMSEHKISSDEPLSLTLRVVPKMLTPLVHHWIPDAFIVSFKLETDPSLLLKKAKGALEKYGHNLVIANELHTRKQKVVFVSKEEDKPVLLSEEDLKNGKEIEEIIIKDMLCQYIKFKNQCGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1Q7</accession>
    <name>A0AAV4P1Q7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_479651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003881">
        <property type="protein sequence ID" value="GIX89696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1Q7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10486" checksum="1E35015CBD847FD6" modified="2024-11-27" version="1">MKFVTHQLNDIIIPLKSLSVISAQLLEDIHWYLLVILKCVNEWHEAGLSGSSTSSSPTHFCCRLTVTVSVTYAIPKASWQFPVRRLAFRKLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4T6</accession>
    <name>A0AAV4P4T6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_350081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004086">
        <property type="protein sequence ID" value="GIX92023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4T6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="479"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="590" mass="67860" checksum="0035EB3BADF38C3D" modified="2024-11-27" version="1">MAEGCRSVTSEFDFTWDIECFEDHVRKRFQEIFSPTFELKCVHVMRFFIRLKLSHTKNDYKLAFSMFAVGGSELREITTRLELSVASEDGGRRFQKSCTLYFPDECGDERERPFIERGAALLEHLSRGRLRLHCHLAASVNPARTAKFNFSADLQNLSNQMEALRLDASMRESVITVRGESFGVHQCVLLSRWPNYPDYIELFKKDLIAPDLHSGLQVIRLSALVEAAAKISPLEMNSKECRERAADMYDLLSPRLFDYLLSYVYSGRLRRISPAEKLKLVRIGRQFGFGEMVERSQEVPAASTGVTRCSTEAHSIEWRCEDTRRWRESRFRPLTQIINAHKEARGSLEVVFFIDSQKQHGDIMLEVCFTSNDLLAAVSCLVTVTKFDSSSVRQSSFTFFAKDFEDPVGRMPVGLSKLDLRDTLFRVEFSFSNDSSFNQNGTGIVSNVFELSAHEVEIVPCLLSYSYQMDFFYEEAEAHDTELIAEGKVVRAHRHILSARSPRFRRDLARDLKRLGVIKHFVNRVGFDALVEMVRYLYTGGCHLEYLEGDGKPNLAQDLCIAGLLYELPDLKEKCYQRLRRRTFRRVAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6U7</accession>
    <name>A0AAV4P6U7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_63841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021603">
        <property type="protein sequence ID" value="GIX91670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6U7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16338" checksum="44BC3E0623504414" modified="2024-11-27" version="1">MEGEQEESLEQMIGQFIECSVTSNPPLLVSTSPEHELTMNTHTHKKTPTFSPDGVTYHDPSGPSKAKLQSVKPTKYALQNTGWGSNVHGGEGCSEGGGACHTGCCADDPSDDQKGARKGTSERKHVWTGFESGFIDYTHITRGTPLSVCVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P8X5</accession>
    <name>A0AAV4P8X5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spectrin beta chain, non-erythrocytic 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Sptbn1</name>
        <name evidence="6" type="ORF">CEXT_224471</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spectrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021661">
        <property type="protein sequence ID" value="GIX92156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P8X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051693">
        <property type="term" value="P:actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10571">
        <property type="entry name" value="PH_beta_spectrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000024">
        <property type="entry name" value="Spectrin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001605">
        <property type="entry name" value="PH_dom-spectrin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00683">
        <property type="entry name" value="SPECTRINPH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0117">Actin capping</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="360"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="594"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="616"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="632"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="675"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX92156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="692" mass="80271" checksum="FD0801E3D8D329B5" modified="2024-11-27" version="1">MNVFSRPNYLTGDLKAIEEQMQALSEEAASLTVQFPDSRDDIQTKELAVLSSWKKCTEKAAIRKDKLQQAEQLQSYFDEARDFHAWIYEMSALITSAEVPEDIVTCETLLVQHEGYKSEIDARFRSFDIFEARGKEIIASGHFLSQDIQTKIDALSSSLNDLLATWNTRRDIYEQTLDLQKLIELETWLNTQEHNLTGEDGRSVEEVEYLIQKYEQFEKKIQLYEAKFQELERSTKIEEDASRLREEKERQKLENERILEQQRLEEIRRKEEERLLEERRKERVPSDVTQREDSYDDNQIVDSSASNLKRIGSTRISVNHKKASRQEQSSSIALNLPIINKKRPTVVKKESIYKKREVPPTTAEGFLSRKQERESNGKRSTSRQWKTLYTVLCGQLLCFFKDKKAFVDSNSAKPPVNILKANCYVPRDYHKKKYVFRLELSDNSSYLFEAQNDIKRQEWMQKINFTASLPPRQQLLSPKENEQFEISIKEESQKTIEELYSTIESKSSEPSDIYDVPEVDDSESLYDTPTETYQGYKFPEMLDTYRDRVPSSVYENTFKTSPVAEEHDPFGAPRTMEEIYGDPSFYVDPFADNDERFSLDENPQSARSSVSNQSSYVTAASNSSISTLQDERMDDIDSDDEQKVELYATTLPRGSRESRGSYPIPPPTPRGSYAEESTPQGSFSNLMQVMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAK1</accession>
    <name>A0AAV4PAK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_176431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004211">
        <property type="protein sequence ID" value="GIX93186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="268" mass="30456" checksum="C0E2A6088451B859" modified="2024-11-27" version="1">MHKLRINLWKSKTPVFRYLNPKRRITDSFCQSEFTNHTCALDGDRKITKTDSVPVESHGGVVCAAALTELVVFCHRMLIHVGMWHVQHIDSVHKRNDEPDATDTRSNALILFYEIRLGLCSQPPPPFLRLRLNKPAVIGKLHDRRYATIYRGGKKMDQLQWMQEEFGNFDGVFGRGRIMALATGFLVGALWERVSILVMMGGSFIVAPEPEKTGKSKGKVAIPILWVVFSPVFPGFGNFDGVFGRGRIITLATGFFWWELYGNEFPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PI80</accession>
    <name>A0AAV4PI80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1758 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_118342_1</name>
        <name evidence="2" type="ORF">CEXT_127981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004550">
        <property type="protein sequence ID" value="GIX95705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PI80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043775057" evidence="1">
        <location>
            <begin position="27"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20937" checksum="10CFF40D32B05312" modified="2024-11-27" version="1">MLLCLCFAQCFLCVKLICFVSHSAPGQKGPVIEGNLPWYHVGDLVNLTCSSAKSPIPVHIRWFVNDMEAKMEHLIKYPTIRYSDGTEVSSLGLRMKVESYHFKSDELRIKCTTTLYRMLTMRAEKTLFRYNQQNSGFHTAENRCAGVIAILLQSCAKPDKGRGRMRAETCLFRHPNRFDGNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSC8</accession>
    <name>A0AAV4PSC8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_145161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005168">
        <property type="protein sequence ID" value="GIY00328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSC8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8584" checksum="D38CF49981986E35" modified="2024-11-27" version="1">MANPRTSLSKTLQVILNLFQGGSMLGLPSTSKKENALSCMMISCLSSVGVIGTKSCDEEKEDGMESTEAEHGKCKERISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSD5</accession>
    <name>A0AAV4PSD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005012">
        <property type="protein sequence ID" value="GIX99188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="19205" checksum="9EC882E00B36B99D" modified="2024-11-27" version="1">MHHEKQFGIMHLSKVAIICYIYYQVNPSKYIYMLIKAYPKKNIHKIFIIADIFLHVPLAHPVGGNTAKPLHLHSFVYSSKYIVELWSFVQNLNEKGEKIYIGNKIFLSSERVPHSHHCPAPTFENGTEQSDYRKVSIQESLVFRDAPAPTKEIKEVGAEERAITHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSI9</accession>
    <name>A0AAV4PSI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_42231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005074">
        <property type="protein sequence ID" value="GIX99664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9686" checksum="A58370FA5633D8D2" modified="2024-11-27" version="1">MVFLGGAGGVLMQAITQTPPNYYYLKTADERNFLVRAAGTMEFELQMCNCAEIEIIVLKAILSAILNKYASPSKSLPSGYFASVSSSVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV47</accession>
    <name>A0AAV4PV47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_293241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005147">
        <property type="protein sequence ID" value="GIY00134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY00134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12413" checksum="CF869B178A220D07" modified="2024-11-27" version="1">MSSLFDAKLIDHERLTLGLDKLKKLADNRSNETSYWENKADDKQEHKLPNGAPSNDSLPAELIRVIPDDNKTSSSAEMDLVCFGLCIGQMSAYEFPHLKSACKRSAWIMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2R4</accession>
    <name>A0AAV4Q2R4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_222691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005492">
        <property type="protein sequence ID" value="GIY02739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2R4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="46" mass="5339" checksum="7B6378C4D09AA8DB" modified="2024-11-27" version="1" fragment="single">MDVTCGQSTEHTTIEYLIIAGQNRKRYSPIERRKTVSVKKQSIRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4M3</accession>
    <name>A0AAV4Q4M3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ZP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_229088_1</name>
        <name evidence="2" type="ORF">CEXT_280111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005438">
        <property type="protein sequence ID" value="GIY02358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4M3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY02358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="339" mass="37746" checksum="B8EE3AE9B17A7AE3" modified="2024-11-27" version="1">MLDKFRKDEDMESSKGGRIESSPDLPTIQENSEESSLEPSMLGLMHVQRPPKSILIRDVSDIYLTTTVETELRELTTKVSRDTVEQHARSVEEPLLEAIAPSRSPLETNNWNVIIRQREPYDPTATETDVDASGESNGESTDEPESTEKPHFDVKIRTIPPEELQPKKPDEMVRIPTLEMPKTVSKLREALAPKTSDEVSRISEPPNGDETPEEKDDAKDKPRTVRWMDDAKDQNPDEVSTVSSSDSFKSAASLRERSSSEVSKVAPTLPSQARVSRHPPMLERSTSEIVTSPEENVRWVGGVVPVLESLSPEFLANIPVVIQGGFFNRQKSPPPGDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5L0</accession>
    <name>A0AAV4Q5L0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005738">
        <property type="protein sequence ID" value="GIY04639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5L0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9614" checksum="854AD40F5CA23979" modified="2024-11-27" version="1">MMTVPESTNDRKLFLSPRLHNSPVCYWQGRAEFRPLIKCSPVRLVVIGNRDTIILTPPLHHERGLGGVEWMKILHLISTLGKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9E7</accession>
    <name>A0AAV4Q9E7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_706401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005983">
        <property type="protein sequence ID" value="GIY06638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9E7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8872" checksum="AEC415D56EE87DAA" modified="2024-11-27" version="1">MACLRPPFLPRGAHGAPAKMGSGRRHSYVSSESLPHHFTTPVSECNIQIRKGSFLLLRFIKYAWLASKTRRGLKGLPGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFR2</accession>
    <name>A0AAV4QFR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_394111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006050">
        <property type="protein sequence ID" value="GIY07119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8800" checksum="3FA5735F3F80158C" modified="2024-11-27" version="1">MTHICEEREREEIIIAPHLFERKEIMADNPENPVLFRLADGEKKRFSPPCYCRRKEEDIRSQTKQKQSRRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQ69</accession>
    <name>A0AAV4QQ69_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_184871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006647">
        <property type="protein sequence ID" value="GIY11434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQ69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="47203" checksum="B3775B78A77D2569" modified="2024-11-27" version="1">MRQRQIEEEMKREREEALAKLQEIEAKKRAKEKEIEERLIREEAAALERKREEEKTLNRAKEAEKPNLSWKERELEKRQRLPREEKDQDFSRNLDDRDRSDAWKRKVDRPKEMEGSWRREEPPTSRRGERFERDRIPWGEKDREYSRKPNDNDRPDAWRRKADRPQERGGSWRREDPPTSRSEQPERDNLSREENDREYSRKPNDNDRPDAWRRKADRPQEGGGSWRREDPPTSRSERPERDNLSREENDREYSRKPNDNDRPDAWRRKADRLQEGGGSRRREDPPTSRSERPERDRLSREENDRGSSRNPDDHDRSNGWRRKTDRPQEGGGSWRREDPSTSRRGERTGRDGDYSRKPDDRDQSDGWRKVDRPQRGSWRREDPPTSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4F9</accession>
    <name>A0AAV4R4F9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BLOC-1-related complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_15051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007385">
        <property type="protein sequence ID" value="GIY16489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13794" checksum="7884FC52CB94777C" modified="2024-11-27" version="1">MDNLSQFSSLNLSGKYPFPKDHQRELVVFRERRTPDSIQHAYRLKDLALAAQNTMVVHLSGELQALTDHYKKEINDMSQMLQDLKSRLPPHEPVAPMNKKTKLTKTLTSSNSKRRSDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6R3</accession>
    <name>A0AAV4R6R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_256621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007527">
        <property type="protein sequence ID" value="GIY17638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11394" checksum="9913B458415EFCE1" modified="2024-11-27" version="1">MNLEGNLLISPLSKAKSEDLPLLRSEIDFTGEGVERSSHKERKYKGSRGKSPASRNWEGVVSKGEAKIVCQVVVTTAIRKIDNSIFSCFSIRYTFGALLLVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJT5</accession>
    <name>A0AAV4RJT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_163691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007998">
        <property type="protein sequence ID" value="GIY21299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9897" checksum="3B9ABE9B46F1764E" modified="2024-11-27" version="1">MDMLEILEKIYYDAKEPGSFGGVKRLSEANCFKKSQVRKFLSGEDPYSLHFPVRYEFQRRKTIAYGVNELWQSDLVDWTKIVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RT32</accession>
    <name>A0AAV4RT32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_128581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008324">
        <property type="protein sequence ID" value="GIY23859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RT32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14790" checksum="AD10A34F5144285E" modified="2024-11-27" version="1">MNRDDRRRSCFVICKANEVTHALQRERRGGGEDGTGMRFGMGMQQNKTRGLFRKAKSKFLPYICIVMTGDEAGLLFAKQMKWHMPCRGRRGRGWNRNGIWNGNTAEQNERNFSGKKEDAENDSRSWAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY37</accession>
    <name>A0AAV4RY37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein Tob1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Tob1</name>
        <name evidence="5" type="ORF">CEXT_802581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BTG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008734">
        <property type="protein sequence ID" value="GIY26803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.90">
        <property type="entry name" value="Anti-proliferative protein, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002087">
        <property type="entry name" value="Anti_prolifrtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036054">
        <property type="entry name" value="BTG-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015676">
        <property type="entry name" value="Tob1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17537">
        <property type="entry name" value="TRANSDUCER OF ERBB2 TOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17537:SF5">
        <property type="entry name" value="TRANSDUCER OF ERBB2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07742">
        <property type="entry name" value="BTG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00310">
        <property type="entry name" value="ANTIPRLFBTG1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00099">
        <property type="entry name" value="btg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160696">
        <property type="entry name" value="BTG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01203">
        <property type="entry name" value="BTG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anti-proliferative protein" evidence="4">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="231"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY26803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="422" mass="45922" checksum="649B378BE4FEB741" modified="2024-11-27" version="1">MHVEIQVALNFFISFLYNKLPRRRVNQFGEELEKSLKQKFVGHWYPEKPYKGSAFRCLKTALPLDPVFDIAAQESGMAIADIQENLPEELSIWIDPGEVSYRLGEKGVVKILYSESDNSEDRADREIYRTFNPEAQCFKPIDSVTSQLGSMSLSSGSSSSSSPYGNSPSPTYKSSSSPINGFLPKVTTPLTFTTATFAQTKFGSTKLKSNGKRSHRMSPTEFSSYIKSRAIIQQQQQQSQIPQMFGSVSQQQRPRSLSPTPPNNNSPLDSNNFMLMASSNMHQNSNYAPTTQSHFSPNQRSSMYDGGYLNDIFSTASTSSGLGDQLNSGGLLTPNSNTASTKSTSNARLGQVVSNANALSLFLDKGPFCSPTSSVTGGSNGSVSYKSSNAVGDNGSKSYGNSIDNFSVGGMSYPNQHLLMAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0N3</accession>
    <name>A0AAV4S0N3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_700501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008665">
        <property type="protein sequence ID" value="GIY26297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0N3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8899" checksum="A15CBB60EF1A6045" modified="2024-11-27" version="1">MVVIKTAHYAHNEPIEMVIPCTIRLLEQIANRYRNGFDCPLFKNSNNPWLMQWFSNWCQLGLLVRLWVACNSSMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S1W7</accession>
    <name>A0AAV4S1W7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_32331_1</name>
        <name evidence="2" type="ORF">CEXT_585071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008836">
        <property type="protein sequence ID" value="GIY27655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S1W7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043954993" evidence="1">
        <location>
            <begin position="18"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY27655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13643" checksum="B7F85390201F0565" modified="2024-11-27" version="1">MLALLSLVFCAAVLVASREIQPRIILEDNHGSEMVQKPIFYFGEMRSTDLEIGDPCSFSFNCLSGCCLKEKNGKTRCRRKQRKDERCSVGQIKLDMYMDYCPCELGNKFCSDDPEPRCIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9C7</accession>
    <name>A0AAV4S9C7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NUDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">CEXT_757201</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nudE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009248">
        <property type="protein sequence ID" value="GIY30559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9C7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:microtubule"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:spindle"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:microtubule binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051642">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:chromosome segregation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:establishment of mitotic spindle orientation"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:mitotic centrosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="10">
        <location>
            <begin position="134"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="22"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY30559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="35411" checksum="BCCFFB07E0AA7AB3" modified="2024-11-27" version="1">MHEQNISFSNIEEERDYYKALAIEYEQKYQETKLELEEFQDSSRELEAELEMQLEQTDARNRELKSLSNRLQLECDNLKDKLQKTQHDSQSQIADLEDELSRVTATRDDLQKYIRELEQLNDDLERAKRAAVSSLEDFEARLNQAIERNAFLESELDEKEALKVTVQRLKDESRDLRQEMVAHHRPVYERTFSEDKPGHIKTVVDSNKIKSELENLPEVPTKRLSSLQLSSSSPLTPSSRISALNIVGDLLRKVGALESKLASCRAYVKDTSSKSEKEEFEKHSQVPPKHLINKSSLSSQDCISLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE02</accession>
    <name>A0AAV4SE02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_325901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009175">
        <property type="protein sequence ID" value="GIY30123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="8903" checksum="09ABE9D8BDE225F7" modified="2024-11-27" version="1">MGFTVRLGVSMLGAQGKTPTDDIFAQQTPQLRRPIHQGALAVSGAPGAPTKGAIENAPRQNHSQRISGGLHGIRQMCRQTSVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SL72</accession>
    <name>A0AAV4SL72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_61191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009586">
        <property type="protein sequence ID" value="GIY33062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SL72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY33062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12825" checksum="AA871F21CDED6C7A" modified="2024-11-27" version="1">MVSSLKWAIDIINLITTSLECVVMETKEKVGDRGSSIFISTSEHKSIKGRHSGNIRKRSMTHLRRKTKRLQYYERYRIKSRDTETNTKKTPRRVGRKTMSEKFSNTKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SR84</accession>
    <name>A0AAV4SR84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding cassette sub-family A member 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Abca7</name>
        <name evidence="2" type="ORF">CEXT_504261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010065">
        <property type="protein sequence ID" value="GIY36585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SR84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="62"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="33807" checksum="1DA63AFABCC41198" modified="2024-11-27" version="1">MLETNIMSAMWDVTKREFQKFRKTVIQQIIQENTMEDSDVLEEEARIKNLTEAHPGSAGEALVVSDLTKVYKNFYAVNHLTFGIHEEECFGLLGVNGAGKTTTFRMLTGDCKPDKGNALIHNDSLRTNLISKRKFQSYLGYCPQFDALIDRLTGREMLELFAQLRGLTGPNLQERVDKMIKMTDLTKYADKQTQFYSGAGVDPVSRRKIWNILSQARNNTGAAVLLTTHSMEESEALCNRLAIMVNGRFQCLGSIQQLKSKYGQGYTLIIKMKREDQNEPARMNAIKAHIQSNLIERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ST67</accession>
    <name>A0AAV4ST67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_486411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010020">
        <property type="protein sequence ID" value="GIY36189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ST67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13977" checksum="722E2B8E43681B77" modified="2024-11-27" version="1">MVVEGRSVVKRCRRFLVDVLTWSTNTPVICDRLPMLLSVQFWSFAFSYFSPCVHTIHSPDWCGRGNKNPNKQIDKRIEWQRNESSDEENETFRSPFEFESGTSNAPAKQTDATLEVKLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SU85</accession>
    <name>A0AAV4SU85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_793331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010113">
        <property type="protein sequence ID" value="GIY36982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SU85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10890" checksum="0423DCB0BF5A83B3" modified="2024-11-27" version="1">MDQKTAGEIQIPLIQHNTHTHTLKTHLMKTCPEARFISAILALNYGMYPVSSAPLHPFSSFIPSIPLFPVMPRYHPGGIGLGLTKLPKCGPGQYILEGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3V2</accession>
    <name>A0AAV4T3V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ZZ-type zinc finger-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ZZZ3</name>
        <name evidence="3" type="ORF">CEXT_682371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010548">
        <property type="protein sequence ID" value="GIY40021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037830">
        <property type="entry name" value="ZZZ3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705">
        <property type="entry name" value="ZINC FINGER, ZZ DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705:SF0">
        <property type="entry name" value="ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY40021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17594" checksum="112BDD17C871AB9D" modified="2024-11-27" version="1" fragment="single">QKLEELVLVKFPPKEIESRRWVKIANCLENRTPVQVASRVQKYFIKLLKAGMPIPGRMPNLQYLKKPKRKNVIRNQASTFLVSQSLPVYMPEADDDICYNYHQPLTSEENSMESKAEMSQKWRLESLPANIRGIRYGNYDVLSMMNWGISC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T467</accession>
    <name>A0AAV4T467_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_74541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010716">
        <property type="protein sequence ID" value="GIY41453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T467"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="7733" checksum="F92394CBEA68DC81" modified="2024-11-27" version="1">MLPENKRTCAAFQPCPPGGARTDTALAACGTPEGGVGQTRNLSGIPTAATERERHTVGRQLSYGKTSVVGPIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T551</accession>
    <name>A0AAV4T551_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP-binding enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_36311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010597">
        <property type="protein sequence ID" value="GIY40314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T551"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9865" checksum="1839B5AD8A49FD7E" modified="2024-11-27" version="1">MFVVEIITVDTFVNTVSRDVAAMIAVMTICGAADIIILFLLSNSRLKNLIEGGLAQIKISHFKIPRYIMFVKEFPKTVSGKIKKFEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TD36</accession>
    <name>A0AAV4TD36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_715971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011082">
        <property type="protein sequence ID" value="GIY44074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TD36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12309" checksum="C34CA9826F2661CB" modified="2024-11-27" version="1">MSKQVMSASFKVIAINPGQEANLSENSTLSRCVPRSLMSKQVMSPLLKVIATNPGQEAHLSENSTLSRCVKEIPPAALSCLSTSVYKKLENPMLLQTNVLIENLLNGVRNQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TEX8</accession>
    <name>A0AAV4TEX8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Agrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_340621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011069">
        <property type="protein sequence ID" value="GIY43986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TEX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000134">
        <property type="entry name" value="Transmembrane agrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000140">
        <property type="entry name" value="Transmembrane agrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.30:FF:000024">
        <property type="entry name" value="Transmembrane agrin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003645">
        <property type="entry name" value="Fol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00274">
        <property type="entry name" value="FOLN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="174"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="248"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="320"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="389"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="6">
        <location>
            <begin position="440"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="5">
        <location>
            <begin position="699"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="5">
        <location>
            <begin position="752"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="699"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="701"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="752"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="754"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="773"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY43986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="837" mass="92257" checksum="BA258D6CBCE5BA1F" modified="2024-11-27" version="1">MECRSSACVSREMLCLRKQSEFETRVCGTDGKDYPNMCELKKTACREMRTLEIRFTGRCVTWWILYCTFKLGCLGSKDCTFLRNLVQDCTCLRNPGAGLHVFKKPGAGLHVFKKPGAGLHVFKNPGAGLHVFKNSGAGLRVLRNMVQDCTPLPGGRVPQFSSVPTDEHRNAICRCNAVCSEDLRPVCGSDGKTYSNECTLRVDACKHRKNIRVVYNGECSAGKNPCENIVCGPFEDCNIDKYGIASCQCQPSCESVMKPVCGSNGQTYSNECELQRDACLMKRHVAVVYKGACGDTGPCHNYVCSFGALCVLKNGRPGCECPTCPERFEPICGSDGISYTNECKMKREACEERKDISIAYMGLCNTCSQTKCEYYAECEQDNKGRATCVCPQRCVKMDAKVCGDDGITYLNNCELRVAACTKQLYINVASKGPCEDGRCVCPTECPENYDPVCSTDGITYRNECEMRRAAHGTQRPHLRRVRRCRRLWCRAKSLESGSGNSPCDKDACRYGGICDYDSDDRLLCVCPFECPPVRAPCAAGRRVLRQRMQDERTVLQDSEENCNSSQKQMPNNVDRDNLYSQIFLKTPLRFNGTPESVEVEEIACDGEKTSNQPCDRKRLFCGDGPGFKNCPPSSYCHKTSEFAKCCKEVVMIKSCADTVHGAAQMEDQCPRTGPGGVSYIPILALLLYNDGFLSILGHCNCNRLGSYSSTCDPVTQQCPCKPGVGDLRCDRCEPGFWGLHKISEGSSGCSPCDCDQYGSVRDDCEQMTGRCVCKHGIQGMKCNICPAGTVLGPDGCMDASIAKSVTGSCDELKCFHGAKCKREHGEVQCVCDFQVHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TME2</accession>
    <name>A0AAV4TME2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_506831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011395">
        <property type="protein sequence ID" value="GIY46291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TME2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11746" checksum="EF209F3B00BAF18B" modified="2024-11-27" version="1">MDSKEQHYFTIGNVDILSTYKNERIFYSSRLVVSKGDLPLDVFEKGDSLQIHAATPELVVICGSKPFPRWGGCGEQMPASASRRLVFEHVQDESLWVGVGSRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRT1</accession>
    <name>A0AAV4TRT1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_85161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011643">
        <property type="protein sequence ID" value="GIY47889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8672" checksum="82EC6609C2D5A433" modified="2024-11-27" version="1">MRTERILQNIRLFHQLIQESCKTGFNLHSYLDENKSIHEAKHDLLITYSLKTRDLTMLRRQAFSELTFWYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSY4</accession>
    <name>A0AAV4TSY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_570501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011871">
        <property type="protein sequence ID" value="GIY49723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043741616" evidence="1">
        <location>
            <begin position="21"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9462" checksum="89F26C2E2B2B94C8" modified="2024-11-27" version="1">MGYCGWVWVTVVWVTVQANALTCIEKIIDKLEKTDILDEVMPMLAKAKIQDPAILMPVVRHETTPILLDILSRLFEITSQFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TTP1</accession>
    <name>A0AAV4TTP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNase H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_270604_1</name>
        <name evidence="1" type="ORF">CEXT_56791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011756">
        <property type="protein sequence ID" value="GIY48821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TTP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16410" checksum="348F2B45F3E1AB0F" modified="2024-11-27" version="1">MYIPIRFFKRLLQLDILTEWQTHWASSAKGRAVFEIFDKVNPKRTLGSFFLNQIITGHGAIASYQYKFFNGSSTCSCGPSIEDRNHILFHYSNWTDIKKKYFPRNYKRSPLAKLLGNHQARIGIELIMKHKLQTILDGLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUM1</accession>
    <name>A0AAV4TUM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Upstream stimulatory factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">USF1</name>
        <name evidence="8" type="ORF">CEXT_622203</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011783">
        <property type="protein sequence ID" value="GIY48997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051732">
        <property type="entry name" value="USF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117:SF3">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="191"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="257"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY48997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="33807" checksum="BAD1FF2A03B55BE0" modified="2024-11-27" version="1">MDLLDEEIDGSSVRTIKTEKDFHLQEVYVNPKITMDVNGDDNANAGRWEVVEVIQDLNSNRSIHPDIICADGLNSQDKVNPDDPPAITDATGTVTYRVVQLAADGSRDDGQGAQIVTTSAAIVAGGQQVTQAIIANPFNTANGSASPGNEGPFYVMMSPQEVLQTGQRTLAPRTHQFSPKLEGGRTARDERRRATHNEVERRRRDKINNWIVKLSKIVPDCTSDHAKQGQFYSQSKGGILAKACDYIQELRNSCARLPDIVKENERLNLDLDALRQQYEEVKNENQALRAHLQQQGIAISSSLASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVH8</accession>
    <name>A0AAV4TVH8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_742311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011849">
        <property type="protein sequence ID" value="GIY49521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVH8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12156" checksum="D213F1070D28A215" modified="2024-11-27" version="1">MSLFRVHLDEQIFPTYCKHPTNAKTTNSKYRGWLLIGCMEGITLTAHLKYGLRTDCSRETRWAGLLAREPICHQQHGFLDGLRLQDGGFRLGGCAAIVFMINKAQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U118</accession>
    <name>A0AAV4U118_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_611831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012115">
        <property type="protein sequence ID" value="GIY51484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U118"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14073" checksum="F23E2F4CE714B7A8" modified="2024-11-27" version="1">MNRNFIHCPLNPTSFSDNRISGFMTLYIACFDVVAIESVVQSIVEATSLTAVTFSEKGTSGPPEKAFGKAQKTPHDVSLSYTHKGSNIILEVFSKPPQWRIPSAIEHKIAALNVKIFFSEKESKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1Z4</accession>
    <name>A0AAV4U1Z4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_271381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012158">
        <property type="protein sequence ID" value="GIY51765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1Z4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10319" checksum="AA19864FC6B178FA" modified="2024-11-27" version="1">MSGRVFNSSVQSVDEIMVKFKGMSTMRQHLPGKLVKRGHKIWARSWVKKKATKSELQSSWVATKKEISCSDFLWNANVRTHMPENGNIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UA78</accession>
    <name>A0AAV4UA78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Psmd9</name>
        <name evidence="4" type="ORF">CEXT_49722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012536">
        <property type="protein sequence ID" value="GIY54647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UA78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000107">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035269">
        <property type="entry name" value="PSMD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="29"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY54647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13856" checksum="05CA8F6292B65D2F" modified="2024-11-27" version="1">MLFTQKKKITPSASCLNVHEVSFKPFARVDLVDENSPAQKADLRVGDLLVKFGTLKYRNFQNLSAVAKLVTENLRKPIHVSVLRSDKVVPLILIPDEWGGCGYLGCRIQPVNPSRVAQSPIERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UH93</accession>
    <name>A0AAV4UH93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012873">
        <property type="protein sequence ID" value="GIY57262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UH93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13043" checksum="24DD5C84D7C0F350" modified="2024-11-27" version="1">MTYRDTAGNSSRTLFPASIGLESVSGSVWFLRSQLSCLLSCRTVFPTSKVGGAIKTEHVYLLWASKGSLLSCTSIFVIVGCDFKKSIPNRIDRFCCRLEDFRFASVLKRVFRRLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNA5</accession>
    <name>A0AAV4UNA5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ATG12</name>
        <name evidence="7" type="ORF">CEXT_366671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Ubiquitin-like protein involved in autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATG12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013193">
        <property type="protein sequence ID" value="GIY59297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNA5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="1 4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="6">
        <location>
            <begin position="44"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="6">
        <location>
            <begin position="265"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY59297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="497" mass="56805" checksum="749763C5A351D6C3" modified="2024-11-27" version="1">MAGTVEGVTIKKEIEDPVGSPEQSDTPDSGLGQTDNQNPKLTKVWTEGETRSLIELAKVYIPKFKDSSYTKRQLLEDISNELQMIGYDTTPDHVRNKMKYLRTRYRNIVNYNLKHVEKRNMQFGDELAELYSLDYFDRMDSFDRNGNSSSDVSFRSSTSKRNSKSVSQSSSSKPVPASHVDLRTVVTTKKRKATQIVHKGTRFAIKRKMNSKSRSQQLFQCGLCMDKFKTSQDLHGHKCKATGKGKNESPKKKTSSSSNSPNVFHWNSLITMKFLELMKDYQDSHKNSNFRKGNLWVNMSALMKRRGYNILPTELEKKWSILSTAFEKTMKYNKTHKDKKKCAFFKRLTELHQHPSSFDCFKANEPVKMTVEVSPFSFASNSSQVNSRPSTANSTSQRKNSEDQKIMPNHNMTVWLKPTGNAPIIKNKKWVVDRNCTIAKIMGFLRQYMKLDSTAAVFLYVNQSFAPSPDSEVGNVFECFNINGKLVLYYSTSPAWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UPY6</accession>
    <name>A0AAV4UPY6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_435961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013243">
        <property type="protein sequence ID" value="GIY59802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UPY6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18353" checksum="50041D19AE391D4D" modified="2024-11-27" version="1">MSLRSRRISFQPDFIHIASLIRCMHHILCSCYRQPFAFDDHLVPVFVVVETCLPLLTRLRLAQGAGCGHPPLWQAIHGAYQPILCCHHTSEPVRLKFLIQTKSVGVIVEINTQHHFSELLVGHFIPFIKSIFHSNFFEIVQLILKKGDGVFRMRSSKLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4US88</accession>
    <name>A0AAV4US88_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_507071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013353">
        <property type="protein sequence ID" value="GIY60639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4US88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12919" checksum="6C01CEAD62DAAB18" modified="2024-11-27" version="1">MQPTVEMECENKTSFSGKDYSSNNLYLPNIQGNQIPERNLVLFTLHNGRNVFVDEFLSEILFFFHQKKNYRKNRICSRRKIEFHLVLDSSAFKRRIETFVTELSKTYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UY88</accession>
    <name>A0AAV4UY88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_5751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013665">
        <property type="protein sequence ID" value="GIY62787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UY88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY62787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12805" checksum="9EABC2E794070E1B" modified="2024-11-27" version="1">MTKAVRTYQGQPQTSQISKQAMTVASQLPQHSNTNNRWNNARNLQQNDERYSHSVNSPRIRDMQPDSSQDGRSSRNLLITKKKTVSQTTKKLKINAFNNHMDSAKKWIHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UYR2</accession>
    <name>A0AAV4UYR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_336331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013679">
        <property type="protein sequence ID" value="GIY62874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UYR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9348" checksum="8B8E960E5581CBC8" modified="2024-11-27" version="1">MNIFTAISFRAEKKTPGLIPSVTLVPPSLQLGLNGLFCMPDSSAKVLLDHCSYWDRTTGPIEKDWMLLTKLQATSRATKARHSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1Z7</accession>
    <name>A0AAV4V1Z7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_621361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013804">
        <property type="protein sequence ID" value="GIY63914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1Z7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="14963" checksum="61FCF6CB3AE3581E" modified="2024-11-27" version="1">MEWEKGWLLFNYSHSIFPKSRHQPCSTRCRVAVATAPVALVGNGMLGNGVIAGNGMLGNGVIAGNGMLGNGIIVGNGMLGNGIIGVTVCLEMESSLVTYEIKKAALKLYQKLMRLLKLDLRLSLGFALPPTENSGGFRQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V467</accession>
    <name>A0AAV4V467_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_403441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013887">
        <property type="protein sequence ID" value="GIY64489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V467"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12122" checksum="5716BE74608EA319" modified="2024-11-27" version="1">MVNVALLIRKPEHAIYQELLGSKLKCKLHLCKNPELSLQFLIAPTPLSHSPADVECDANIQNISHSVISLRQLRSTKVHRLQRWLYIQYKKISLEYFIVFIAALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V554</accession>
    <name>A0AAV4V554_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_774261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013964">
        <property type="protein sequence ID" value="GIY65124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V554"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13668" checksum="3691A1EDC0D099AF" modified="2024-11-27" version="1">MKLIPTRPSINKSHSYVSSTPRSYRTVNNNKSHEYRNFVAASCSHKSRRKCRIAGMHTVNSHLQLVTERSLFFLLTMRPMSFEGSISFNRRSYNDVMTKKKGRSFLGKVAEIEIGLRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V7P7</accession>
    <name>A0AAV4V7P7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_642411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014102">
        <property type="protein sequence ID" value="GIY66257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V7P7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY66257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25233" checksum="C3481AC8BD486CE6" modified="2024-11-27" version="1">MLKTGLSVWLIPQTLFLSPNSIMEGYPKAIGEFFRRCMGGKVMAQERIDSEEKRICPTDMAQSEAKAQRKEKKKCPDIKGTSKQVDDISSPKQITLAENRERKKLHLCRAETVFCTNKITVKCVRKQAQKMLNPRTVGVVDSPNPIFIPKPIMEGYPKAIGELFRRCMGKKKKKRENGTGSNRDRKRKEYVPLTCPEVRQKHREKKRKMSGHQKGQRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLJ3</accession>
    <name>A0AAV4VLJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_683941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014733">
        <property type="protein sequence ID" value="GIY70903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY70903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9374" checksum="568F1C7FFCB8BCFA" modified="2024-11-27" version="1">MELGPVIDKRERFLRPTSSKSPGRDVGNGRSIRSGHSGQLLTSSDPLDGWWTTRQIHLKDAPPLHPQSFVHIHSHSLSIPLSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VLY5</accession>
    <name>A0AAV4VLY5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_384381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014772">
        <property type="protein sequence ID" value="GIY71247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VLY5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="18897" checksum="8A3F6F70BC888006" modified="2024-11-27" version="1">MERSPKLLTEIEIDEDSEIDNGDNGSEENLEVEIDEDSEIDNEDNGSEENLDVDIDEDSEIDNEDNGSEENLEVEIDEDSEIDNEDNGSEENLEVDIDEDSEIDNEDNGSEDILEENISDQAIANLIEAIANLIRNGLHQKMEYSGRKQNLGKMHVLVVIILCLTDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVW5</accession>
    <name>A0AAV4VVW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_146701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015234">
        <property type="protein sequence ID" value="GIY74587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="6088" checksum="3B423E3AE981576C" modified="2024-11-27" version="1" fragment="single">MVLLGILTAVKEDLQIPRSELMNGSSIQPASQEDMLDILVILPCDDDFITTLRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VX38</accession>
    <name>A0AAV4VX38_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin-containing monooxygenase</fullName>
            <ecNumber evidence="5">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Fmo2</name>
        <name evidence="6" type="ORF">CEXT_678021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01015265">
        <property type="protein sequence ID" value="GIY74847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VX38"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY74847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="159" mass="18542" checksum="786F02E85B01AC2C" modified="2024-11-27" version="1">MDLKHPTLAIIGFVESQGPISTIAESQSRWAARIFSKNLKFPNKDIIMKRMKSKVTRNTSVMEDYIEYMNDLAEEYGAKPEISTLFFKDFYLGLTCLTGPFLSYQYRLNGPHKWDEARKTIFECSDRVMHPLSSRISISKLFMNNNKNLRDLEELKGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7K6</accession>
    <name>A0AAV4W7K6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_424841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015811">
        <property type="protein sequence ID" value="GIY78865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7K6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18531" checksum="1E27CFB08C515898" modified="2024-11-27" version="1">MWTPASTHTATATPINFISYINTLHEPTPSTELHQCESAAFDADGRPLSGRLYAEYMHGAVSDIEHTSNRYRVYEEEGLCPRSVLNRFLGDVQFAVCCLVREVYRSGVLVTGCALQALFLQLAYSLRLSRAMNHQKKGAQAEKHTLRLSGIKCWNLELKEPSSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7V5</accession>
    <name>A0AAV4W7V5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_275026_1</name>
        <name evidence="1" type="ORF">CEXT_502981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015630">
        <property type="protein sequence ID" value="GIY77460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7V5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18711" checksum="F11007A783642FCE" modified="2024-11-27" version="1">MPGVSQTAAMNGKLVIHASGLSPSAKKKNLNKKSFWVLVQVFEIPPTNRRQHHEKPPTGLNIQNSSRRSAVIELCCCLPSRIHIGGLFEHDDDENELAFRVAVDRLNMNDTLLKNSRIFAMVEKLYSEDTLKTTELWHLKKKIQNICTLISSVRNSRSSAVGCSKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W976</accession>
    <name>A0AAV4W976_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_395211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015866">
        <property type="protein sequence ID" value="GIY79282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W976"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12118" checksum="9F38901E4233DD08" modified="2024-11-27" version="1">MRGRGNRQGITTQSNASPLPGCFSTPPFISLPSAAFNRLTSQKNCSPSPFGSYLPVFHHHPFRHPCLEHVPSEEKNIEGRRKKKNDSGERRFKSYVRWFQLSSCSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9H9</accession>
    <name>A0AAV4W9H9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_97432_1</name>
        <name evidence="7" type="ORF">CEXT_433871</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015881">
        <property type="protein sequence ID" value="GIY79387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9H9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251:SF51">
        <property type="entry name" value="CUBILIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="6">
        <location>
            <begin position="9"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="6">
        <location>
            <begin position="130"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="534"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="632"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="566"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY79387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="726" mass="80284" checksum="F545AA11CA564450" modified="2024-11-27" version="1">MNERESVENTTSLTKKPADPTAANSQPQIPQRCSVELITCPSCHLHITIQKLAIPSCSNDKTCRCDFLWIKESAYSKSGREYCGFKENGSLDLVYESKTKLVSVDFLFSGNYKEAFSIHFSAKKNVYIYKGGFEYYQANNSSGVIKSPNFPGGYPSDYSAEFILQNVDITGFVQLIFTDFQLSLWSYIEIFDSNGTRIDVYNGNTFRPPALISSGPTLTVKFQANDEYPSTGFQAKYTFVSYLEKYWINRPSTDCGGFVEDFGGAITMMNMVPSNTLRAFDCIWLIRPRNSHIPETQVSIRVAQFEEMGPKSTLTIRQGQHSDAPLLESVTTFQHHKMPRGQEFVVSATSGFYIRLVGYFTNKSHLAIIYTTFRYEGCYGAADFECENGRCIKDALRCDGFNHCGDGSDEASCYGVNPGTAIPEDANWWRTLTPNYYFPKSESGSGAGTNTLILVTSLAGLGMFVLTTIMILVKLHRQRHEDSISREILHTVSGDLDMENSPNHQGGSELPLYDPPPSYEDVIKLYLPPPPPYSTINRAPTRLNRSRTGGVDNRGYRNDSPGGVRVHTRRSRGSHQSRIVPQENLHPLILKVSLPEENLSIPILSQRNGTVYDPASGSNINVLALTSVFEQDSGGESTNVKTAADNGHEENKSGTDTLGGSKQSNSSLPNSSDNDNVEACECEGACSCKLISKTKQIAIARCSSESRAASTSNASFISKVRWGNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WA00</accession>
    <name>A0AAV4WA00_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ceramide glucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ugcg-b</name>
        <name evidence="17" type="ORF">CEXT_409001</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1&lt;-&gt;1')-N-(9Z-octadecenoyl)-sphing-4-enine + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:70247"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:77996"/>
            <dbReference type="ChEBI" id="CHEBI:189081"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:70248"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>UDP-alpha-D-xylose + an N-acylsphing-4-enine = a beta-D-xylosyl-(1&lt;-&gt;1')-N-acylsphing-4-enine + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:70243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:189068"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:70244"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.80" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01015798">
        <property type="protein sequence ID" value="GIY78796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WA00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008120">
        <property type="term" value="F:ceramide glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006679">
        <property type="term" value="P:glucosylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02520">
        <property type="entry name" value="Glucosylceramide_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000041">
        <property type="entry name" value="UDP-glucose ceramide glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY78796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="399" mass="45722" checksum="C35FE39447CE41F7" modified="2024-11-27" version="1">MVLLFYTLYGFAIFFFGGWCFVWLLHIIAILNGKLKLHRKPQLPSPEVPLPGVSILKPLTGVDQNLYTNLESFFTMNYPKFELLFCIEDESDPSIMLVKKLIEKHPEIDASIFIGKEEGGDKVGVNPKINNMNPGYEAAKYDLILVSDSGIRMKEDTLLEMACAMSENVALVHQMPFTCDRNNFPSVMEKVYFGTSHARIYLAADLFRINCPTGMSALMRKKLLDEVGGIKAFGQYLAEDFFFAKSFTDRGWGIRISSQPAWQNSGICEIKNFNNRISRWAKLRFAMVPYTIVLEPLSECMVLGACAAWALNVLFQWDVFVVYLVHILAWLILDWALLNIIQNNSLPFSKMDFVIAWTFREVGAFYHFCLALFDPKIQWRTRTFYLRWGGLAEEVSPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7N6</accession>
    <name>A0AAV4X7N6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">adenylate cyclase</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Adcy2</name>
        <name evidence="15" type="ORF">CEXT_572291</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01017260">
        <property type="protein sequence ID" value="GIY89779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7N6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007193">
        <property type="term" value="P:adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627:SF12">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="14">
        <location>
            <begin position="37"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="191"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY89779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="655" mass="75221" checksum="0109AF49D9228978" modified="2024-11-27" version="1" fragment="single">MTCALCRAASCTRTSSTHAAGGQPQGVRPGATPQRPFGRLDESAEKNGCMRIKLLGDCYYCVSGMSDQSPRHADNSVLTGLAMIDIIRSVREKRNVNVDMRIGIHTGNAFGGLLGLRKWQFDIWSKDATIASHMEQGGVPGQVHITQATRDQLQDDCYDIQPGEGHLRDSYLQDQEIKTYLIKPFPPKIENENLLDTPDRDRRNNNSNNNSVRFQRQSSTQSNARANISKLQKRQSSHDLIPMSRRGAIGYSLHQYRKMVSQVNKIMENTIDKMALSKKRVRIRLFILSHLNPQWFSNVGIQPLLLTFREFSNELPYLNEPDPLFKHYLMCMLIIFLGITVIHVLIWSSTLEFWITYGFVLLFITAACVFAWIGYIWLFLKEDENDIALDSSALRISRMVWKTTALRVIIWLAISSMILFCSIVGLNECLDSSFFRPPKPANNTQSNLTLDSEDADDLSCAYPWYYTLCAALAMTTTSVFLRIHFLLKLVVNGSSLAIFWYIIDVRGEELFRQQAAKLADWEEFDLPADRSHCYYLLFVLLILHVVDRQVEYVCRLDYLMKVKLKAEQEEARNMELINKILLHNILPPHVSRFYLNRQLEEDSMRVEPYHEEHCAVAVLFASIPSFADFYYEDGQNEEGLRCIQLLNEIICDFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9W0</accession>
    <name>A0AAV4X9W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_638891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017339">
        <property type="protein sequence ID" value="GIY90689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY90689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9093" checksum="9C8FE9DF1D2D5593" modified="2024-11-27" version="1">MNHGKRNVLEAITSSQNSPPEISKSKHSWSAIITALLLKDVLHRCKALTQICGIAYHITHLQVLWEFNLMLSRPDRPMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC81</accession>
    <name>A0AAV4XC81_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_180951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000007">
        <property type="protein sequence ID" value="GIY91399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC81"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="22050" checksum="113B4B045FCD6F19" modified="2024-11-27" version="1">MLSSSVVFFDYYFDDDAPRSECSVSESSQVAQFWPSSKTTKKRFSAVMTVGKDFVLVILCPRRLESSGWALRCLFSVSMSENQDFAPGSPPYLVLGFCPGRLEASGWALRCLFSVSDVRKSGFCSGQSAFIWYCWQSSGHHPKRFSGVMTVGNDFCFSGFCPGRLESSGWALRCLFSVSDVKKSGFCSGQSAFIWYCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XE13</accession>
    <name>A0AAV4XE13_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_80451_1</name>
        <name evidence="2" type="ORF">CEXT_110151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017663">
        <property type="protein sequence ID" value="GIY93471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XE13"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043641043" evidence="1">
        <location>
            <begin position="20"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="258" mass="29001" checksum="7F5315429008935D" modified="2024-11-27" version="1">MRAMLVAFSVVTFVALGCATPLKRDKRFAAAFAGFPFGPFVSSGSFYPIPIPSFYGSRSQPVQPMFPPMFPFNFGPFPMPSFPDMRSWYEGTFGRHHLNPLYLPTLCCIKRHIDVASIILNISITQGFDNLFSDCKENVCKESKTYNDQMPDEFDTFLNDDDIPNMSSNFNHEQESCRGNDKKYVCIKRNYDSSGKAEIVATKYECCHGFVRNPNGVGCIESKRGERPMSSNEQYSFVPVRSASQSSSSSFSAKVSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGD1</accession>
    <name>A0AAV4XGD1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_11201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000293">
        <property type="protein sequence ID" value="GIY93692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12339" checksum="7B53C9075FBBF760" modified="2024-11-27" version="1">MNPNLGTQSPGATCCVLIFAPFSIPQKHQLIREIYRQLGNYLPPPPLCLGTCNQGTYHGSPLLSLLSADCIRLFCEHDPNHSKNTPLPDPHTNSRLAQTIPFATPEMMDDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XRW2</accession>
    <name>A0AAV4XRW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_479751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018078">
        <property type="protein sequence ID" value="GIY96706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XRW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="26755" checksum="6B056CFB4BBB3D7E" modified="2024-11-27" version="1">MSPTSLSEDCHTDELNSRVPSGIENDIGPRKNSNYPKNGRRTAFWGIIPDADDNESLRSNCQTIIRPSGLKRSKFNTWFTSVVIFGLCFPGEIFCGYQMASHGMSFTKCAIWDSEQYWSAKNSKNDPKNGRRTAFWGIIPDAADNESLRSNCQTIIRPPGLKRSKFNTCVPSWIENDIGPQKTPKNDPKNGHRKTDPAFWGIISEADDNESLPSNCQTIIRPSRLKRSKFNTWFASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSV1</accession>
    <name>A0AAV4XSV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_52750_1</name>
        <name evidence="3" type="ORF">CEXT_527791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018197">
        <property type="protein sequence ID" value="GIY97663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15343" checksum="570FA459FF93DCE1" modified="2024-11-27" version="1">MDLDSNSRHELQAAIDRTNGAQSLKHFLFEKSQKGEALKEEEEEYVDLLNRQEVIERQLESTTKQRDLLKEEIQALTIDGELLQKLYAQRDELLDFMVVESPTVNDLHYSSRFLVSSPSIMVCGAIPFYFAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVH3</accession>
    <name>A0AAV4XVH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_171091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018280">
        <property type="protein sequence ID" value="GIY98333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9649" checksum="863484E668C7E545" modified="2024-11-27" version="1">MYTHDVRIGDNPFLEVDGTAVAVPGVSRQRDPAEIFLGVQGPVGGTRNWLLAKKRCTIPSEDELLPWTVGCYSLRLACNIGLNLNVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX28</accession>
    <name>A0AAV4XX28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_722941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018454">
        <property type="protein sequence ID" value="GIY99727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9553" checksum="9D69399FF20DC931" modified="2024-11-27" version="1">MGRSTACSTLHAGKDDPLRKQDNVELMYLDPEVMLSEVEMNHRFILLPIEFQDVLGFVIFFSFNSSYREEINLSGEMDSDFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2L9</accession>
    <name>A0AAV4Y2L9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_426611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018660">
        <property type="protein sequence ID" value="GIZ01398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16633" checksum="CA26782FA63E5CB1" modified="2024-11-27" version="1">MRGINYRMGGGGGGGRFPVFSAIRHARAILKRLNLNVKLIFEFVNDNKREHQYIGVISERAKCKRLELSMELFYELLGEIQEENPGLTFSAAFLCNLEETPDRFMMELVARANGSVAFDRRKVLTREDLKHILQVQGAPNFISESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAB1</accession>
    <name>A0AAV4YAB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ERI1 exoribonuclease 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ERI3</name>
        <name evidence="5" type="ORF">CEXT_786651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019002">
        <property type="protein sequence ID" value="GIZ03844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051274">
        <property type="entry name" value="3-5_Exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044">
        <property type="entry name" value="3'-5' EXONUCLEASE ERI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044:SF61">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="4">
        <location>
            <begin position="52"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIZ03844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="348" mass="40196" checksum="7949E6D3D95A7353" modified="2024-11-27" version="1">MSSTSKRTFCNMMCKRNFSDTAESIQERQITVPSFVKLPPRTGKFQKQKFDYFLVLDFEATCDSPKTVIPQEVIEFPVLKVSGVTFETESVFQSYVKPEIHPELTKFCTQLTGITQETVESYPKFEEVFEVYFLEWMKLENVFNSKFTFVTVGDWDLKYLFPIQCKGSRISVPQYMKSWINLKYTFQEVTSVYPRSMITMMKYCELLHEGRLHSGLDDCKNIAKVLKNLGERADGFNKLGRNVLPLRTILGNTKSAKIPAYRFIVLATVIDTTAFGSSWCVDFRFHHQFALAPTTIADSTLPRGIRISLPQFGTFTPRETSWGLCTSFYHFELKQNIVSNSYFKCLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAE1</accession>
    <name>A0AAV4YAE1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF885 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_169630_1</name>
        <name evidence="1" type="ORF">CEXT_529641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018911">
        <property type="protein sequence ID" value="GIZ03159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAE1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="23084" checksum="EF3541C6EBD98F48" modified="2024-11-27" version="1">MSGGPAAYYLAGTFDGRRPGVFYVNSGDVKSLPKYDMVSLALHEALPGHHLQACYLMETEDLADFRKYIEDRKYSESPSRFPLHTAYMEGWGLYSEYLGLELGLYDDPYIKFGYLSHEMLRALRLVVDTGLHAFGWSIETAVNYMLDHTAVSKKCIEREVNRYITWPGQKKSFPSQFHLIMNWEAPWAATSCTLSGLSKVMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAJ0</accession>
    <name>A0AAV4YAJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_40321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001598">
        <property type="protein sequence ID" value="GIZ03380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16926" checksum="1C0FB749FD625AC6" modified="2024-11-27" version="1">MGKGEGVKESSGTIRETYHRYHYQNSHLPSTLCPTPPFAIKKPLPLNSNIPNNSHPRHRSRKQDNWKKDKIEKETPPPQSKWRKRNETQAQAPNCAGKEKNTGKESFLRLITASLRYFSKCRYFHPPIASLQRLAFSGGDDPDPITES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBK9</accession>
    <name>A0AAV4YBK9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_40331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001598">
        <property type="protein sequence ID" value="GIZ03381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="24038" checksum="EBA2B7C2144C16DA" modified="2024-11-27" version="1">MDAVLTHKIRKSKGVQRQREGGNTSGSSEYGTLPRCSPTSDTILIEFFIFPPQNFPTGRKEARIFEWKLLGLIITDVIVRGMDSDENGFELTHADVFWFVMEGSSIVNLTRVQEDFYVNQIISGHGTLGLPKQIFGKAAACTCGHSLEVRKHLIFDCPQWDSIRQKFFPPNFKKSAIDLLIFNNKSRNGLREIMKHKFQTLLSSLENEDTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBM0</accession>
    <name>A0AAV4YBM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_36400_1</name>
        <name evidence="3" type="ORF">CEXT_319861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019164">
        <property type="protein sequence ID" value="GIZ04891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043585133" evidence="2">
        <location>
            <begin position="18"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ04891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14012" checksum="C8813D5E450BCA1C" modified="2024-11-27" version="1">MTLFIFFVLLISSSGYANPEERREPQYSPASSIHHEPTYASASEMSAYPQHLDLDTLKSMPLVILHPRTPITFNMIQGENMKDLYKSLTPERIVKLLQSASSGSSREKFHHHQTGEAQDRPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDB7</accession>
    <name>A0AAV4YDB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_160611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019311">
        <property type="protein sequence ID" value="GIZ05402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YDB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10914" checksum="806A1089B628C6C6" modified="2024-11-27" version="1">MSIFSSLFPENRANSTQTAVSQFVLPKTNIGSFPEVVKPRTEFKYAFSCSLSNNFNFKTLSNAPLHAQFRTTRSPTGANILCFCREDMQINLPKSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YG51</accession>
    <name>A0AAV4YG51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_388771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019312">
        <property type="protein sequence ID" value="GIZ05411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YG51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="208" mass="23855" checksum="7B312AC7EB48982F" modified="2024-11-27" version="1">MASAFISVRCGWEIDGLHRKVFEFCLKKALKALVVCIRNQARFGEVSPTTRKKKDFCPFLRGIEARHDFCKLREDRTLTFPGVRKGQRWPITALLLNPQVFFSSPPFVVGVLKQFSCTECTMEFHLPPPPPPFHPVLAPFMRHLPLPDDRDELRLFMRSAEHHGMISNSFLFDLTPPSLLSGHSLAFFFLRLVAFEFVVNKVVKLGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCL5</accession>
    <name>A0AAV4MCL5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_797691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002069">
        <property type="protein sequence ID" value="GIX69633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCL5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17090" checksum="EF9A37CE74E0194F" modified="2024-11-27" version="1">MRKCVFMPMHFDNFSIFNGQVANFVIILATVIDCIQLGNKKGISCYAITKHTGNVELCSGVEKSLFLYWLVRDLNALGQWSPNCSTHIPEGYEDDIWDTRATEGTRKMKDTSQHSRKTALCACACINNEGDVFLSRIVTGDGAKEMEDRKWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MH88</accession>
    <name>A0AAV4MH88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_184291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019798">
        <property type="protein sequence ID" value="GIX71874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MH88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16980" checksum="1AFD5BB23F1B45F0" modified="2024-11-27" version="1">MTRTTGQKTEIGEGPLLRNTERVSLTVESCLEHFELVFRFVVFPVQPWKGLNKDREKKDFEEWHFRKRRIDHQNCGTENRNRRIQNTERASLTVDSCFGTFRICFRFVVFPRAPEKGHNKEREKGHKIERRREKNSMGTIGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MI61</accession>
    <name>A0AAV4MI61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_637641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002245">
        <property type="protein sequence ID" value="GIX71674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MI61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13157" checksum="36579E55F5BF3F52" modified="2024-11-27" version="1">MNRSVLILCDRCILCGNTKGYCVLSKVGRKLPNGSCHCAFLACAGQSFPVWLFPGLHGTQPRLKLFDKQGPSLLGRRFIDEKVINLIVSINKNPLYLDQNNLNNKQYPKKKIYIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MK86</accession>
    <name>A0AAV4MK86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_775371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002291">
        <property type="protein sequence ID" value="GIX72215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MK86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7891" checksum="FB77B94C8740CF49" modified="2024-11-27" version="1">MTPIELPIIIINIITGPPWNCCASGQTLKFHLEPGISSISNNSTSYTTTISPRIKQPEPIQDVRVAATAEEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MNF5</accession>
    <name>A0AAV4MNF5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_161671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019904">
        <property type="protein sequence ID" value="GIX73016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MNF5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8206" checksum="DE1B58173EF0B4B1" modified="2024-11-27" version="1">MHYLLRPSQSESGAASAPMRTGTSDWPDHLHPWGNRFAVNASGHALAVVVHSCKYNCGGNNCRNFGNCVTEMCGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N107</accession>
    <name>A0AAV4N107_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein ST7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ST7</name>
        <name evidence="9" type="ORF">CEXT_452123</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ST7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020410">
        <property type="protein sequence ID" value="GIX78445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N107"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd11557">
        <property type="entry name" value="ST7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007311">
        <property type="entry name" value="ST7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12745:SF6">
        <property type="entry name" value="PROTEIN ST7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12745">
        <property type="entry name" value="SUPPRESSION OF TUMORIGENICITY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04184">
        <property type="entry name" value="ST7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX78445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="535" mass="60528" checksum="112C389A11E1B1AD" modified="2024-11-27" version="1">MASLFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSLNHISPWLGGGDGNGDTASNGSSSEGGGGDSGGGGGSGNGNSTNNNNQQAAFECKVWRNPLSLFRGSEYNRFLWTTNKEPLTYYDMNLSAQDHQTFFTCEADGNKPEYEIMQTAWRERDPEARVKAAHQALEKNPECAPAYILLAEEESSSILESEKLFRQALKVAEVNYRRSQQLQHQGPTQETMHRRDTNVLVYTRRRLAMCARKLGKLRESVKIMRDLIKEFPMMNVFNIHENLIEALLEMQAYADVQAVLAKYDDINLPKSATICYTAALLKARGVFPDIASKRGLSTAEMNAVEAIHRAVEFNPHVPNYLLEMRSLILPPEHILKRGDSEAIAYSFFHLPHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPTCTETTDRELLPIFHEVSVYPKKELPFFILFTAGLCSFTALLALFTHLYPEPMGTFAKNIFSDISLCCNTERLKAVGWLSLPLGYMLEKVEAMLPSSLLHQLSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N6M1</accession>
    <name>A0AAV4N6M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Rnf31_0</name>
        <name evidence="2" type="ORF">CEXT_435531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002994">
        <property type="protein sequence ID" value="GIX80029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N6M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19815">
        <property type="entry name" value="Bbox1_HOIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047543">
        <property type="entry name" value="Bbox1_RNF31-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="21464" checksum="A8779E81FDEE2226" modified="2024-11-27" version="1">MEETNNADNGPIPKVDDLSSSPAKSCALCGCSTPAVRCDRCSSQTFCLSCDDMYHKHPKRRLHLRKAVDSIWNSARSPRLRRRTDLPGDPSKIPIPPPRAKKRERHTIGGRMFLKPSHELGSFGHSKVFDIRSFTPPMKDVFAGSKTPTSIEGTYENETSFPAPSTENTTKPNDIYENENVSVSIQFLLIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8F9</accession>
    <name>A0AAV4N8F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_156761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003097">
        <property type="protein sequence ID" value="GIX81112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10440" checksum="253A7348CED31320" modified="2024-11-27" version="1">MLIELFALVLWTSRERRIKSGDFLIVDMGLIRNQHQPFSFLSPERCEAPALESDIVRKKSCKEKNTGKRVVIRSSHNSWIRKAKFGIVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9R9</accession>
    <name>A0AAV4N9R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_780441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003111">
        <property type="protein sequence ID" value="GIX81271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13145" checksum="341A6E2CE7AA6D6B" modified="2024-11-27" version="1">MVVFVPNAFKQDQFAVIFVFGCRRIKNGKHTSENENVYEETCLSKITVVELCSNFRAGRDSSQDLVDLGGHAQPIQTTTNRQLIMRLELNVAYPFVHFQKVLDINLCKLQRIIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHL8</accession>
    <name>A0AAV4NHL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_798971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020948">
        <property type="protein sequence ID" value="GIX84277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8745" checksum="1C76A75ED4A56F55" modified="2024-11-27" version="1" fragment="single">MFGSYFPDTPFRSETGPPPLNLLPSSHSAFFPVRKTIIARAIKFNVFHHPNAPDRTRARVQRKALLLMNRGKKGRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHS9</accession>
    <name>A0AAV4NHS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">KCTD8</name>
        <name evidence="9" type="ORF">CEXT_172851</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Neuron projection</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020951">
        <property type="protein sequence ID" value="GIX84337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22204">
        <property type="entry name" value="H1_KCTD12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057093">
        <property type="entry name" value="H1_KCTD8_12_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499:SF136">
        <property type="entry name" value="GH08630P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499">
        <property type="entry name" value="POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23110">
        <property type="entry name" value="H1_KCTD8_12_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Potassium channel tetramerisation-type BTB" evidence="7">
        <location>
            <begin position="17"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="KCTD8/12/16 H1" evidence="8">
        <location>
            <begin position="106"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX84337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="225" mass="25538" checksum="A984CF8A3CDB2279" modified="2024-11-27" version="1">MAAMAFDNGEDTKFHVIELNVGGVFYTTARATLIKEPGSLLSQWFSGPISAGPFRDSKGKFFLTEMEFYSGTSLDYLRDQKLVLPENFHERRRLRHEAEYFNLAGLGYRGTFAFGRDGLADVKFRKLTRILVSGRVNLCREVFGETLNESRDPDRGTDYRYSARFFLKHNFLEQAFDNLQEAGFRCVAGAGSGTSCGGVGEPMKPGMDSEENRWNHYNEFVFSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIZ5</accession>
    <name>A0AAV4NIZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BED-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_181480_1</name>
        <name evidence="7" type="ORF">CEXT_583191</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003428">
        <property type="protein sequence ID" value="GIX84458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02892">
        <property type="entry name" value="zf-BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00614">
        <property type="entry name" value="ZnF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX84458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="273" mass="30809" checksum="640AF0C6BDCCBD91" modified="2024-11-27" version="1">MSDEEKSPKFEERGKGGPKSQSWGFFTRTQKGGICRICDKEVNLRNGSTTNFRNHLRRKHEEFWNACMERRLDLKTLNISERRISDMSPNLSDMSDDNSPSDVEIAVQHIQAYNPGDTIIYLSSPQTAHMTGESNQSPATTETITANGEIVSIPIEKQKTVSSLLPEAELNSNPSRKINTPKKFVRKSFTKFYRESSPSLKTVGHKIIKSYPDSSRNSIQMSDEADEGIDQFSCFGKYVASLLKVFPCRQRACTLQGEIINLILQDQLKYGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NPH0</accession>
    <name>A0AAV4NPH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_437561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003607">
        <property type="protein sequence ID" value="GIX86692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NPH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11596" checksum="FBAC83DE4515C94A" modified="2024-11-27" version="1">MTFIRDFYMPGSFLTLVRERGAINYSSPIKAIALYPNSVKAGTFSEEVSRKPYFGNGIPRRNTASTITSDDYANSRVVIPSGGTQKWSSKYSSASEEAKTVLMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQY8</accession>
    <name>A0AAV4NQY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase 47</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Usp47</name>
        <name evidence="3" type="ORF">CEXT_106721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021118">
        <property type="protein sequence ID" value="GIX86195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045578">
        <property type="entry name" value="USP47_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19718">
        <property type="entry name" value="USP47_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin carboxyl-terminal hydrolase 47 C-terminal" evidence="2">
        <location>
            <begin position="306"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX86195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="542" mass="61980" checksum="B9C6AF581BC4BAA3" modified="2024-11-27" version="1">MHIQFAFTCPSPKVDKANIDRLKLYEDISDDEKCETSEEELDDCGDTVDAKVTPEKVSCDKYSSKACSTLNGSWFNQHFTSNVPNDCDEGLGEIEVGDTASNNCQGINQAIHSDQSEDSSLTDSERTLVGDELSPRNNSPDIMGTEMEQDIEPSISDVTKPECDSLLMNSENGCGLMCQNKCRNLSSPEENTEDFQYCNHANCTPKPSLCANQPVKRYFRAWPYNDYETGERMLRVYVDKRITLGELKKELESHIGIKADNFKIFRVYSNNQEFECTKLSDNLMSYGDDSRLTIKLGRALRKNEYKVKIYQFAMNDSEPIKFLIDWVIVKGMAVLKLKKEILPHIKETSGLDVPLNRCRLRKKSWKNPGNIYFDHQRFDKDIPVNSNWEMFLEVLPDAEPVTSNKQLTLFTRLWHPAAYKLDPFKEIVIDDTRFETLLQQLHQISGIPEEFIEIAKGQGTFPVKDKKRRVKKKLSDVEKREITNKENARSNKNLRGYSSSPRKEKALKIYTLDSPSTTQASQSTQYRNSSTQSAQHVVPDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSM3</accession>
    <name>A0AAV4NSM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_802721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003669">
        <property type="protein sequence ID" value="GIX87285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9157" checksum="18E595CFC46A587B" modified="2024-11-27" version="1">MATREAAINAANISRYIRFVPDGHVGTRRRGRPPETRAPAGERNQAEHTLEQGRSMERGQFGDFIADSWREERKEKKSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NV64</accession>
    <name>A0AAV4NV64_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_84601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003716">
        <property type="protein sequence ID" value="GIX87861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NV64"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11919" checksum="F8E90C3146620271" modified="2024-11-27" version="1">MGEKQSEPSQVKQASGPRPLSPSTGQRRLLSEGRVLMVCKHGERFEESIRQACSRWRSFGTPVTHWGKFRWLRENWSKYRHLNLGIIMLRYFGKGLNEVKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYF9</accession>
    <name>A0AAV4NYF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_559211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003891">
        <property type="protein sequence ID" value="GIX89844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14755" checksum="40FFA6190CCC190F" modified="2024-11-27" version="1">MTPSNRNSLAKVRRHKANAFISNFRAWYLGKGVVVGKGGWRWNDLHITCSADETDRVLSCSVSSASLSVANGILESVEFCLDFSSLHEILLTLKDRIVTYAHILETEGASLKIREYERGVWARLKFLIEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P014</accession>
    <name>A0AAV4P014_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_544651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021494">
        <property type="protein sequence ID" value="GIX90346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P014"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7534" checksum="96E50DE9E8FB8A55" modified="2024-11-27" version="1">MISYIWPAMITKYDLRGTAEMLKVTVTGSDGQKFIGGNGVPIVYSRDVWLLCDALASRQNWLLPERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1W0</accession>
    <name>A0AAV4P1W0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_457881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021502">
        <property type="protein sequence ID" value="GIX90548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1W0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12646" checksum="848214EB170668C1" modified="2024-11-27" version="1">MWLEEAQNLKSQNSATSTLPQVRKIQAAAVSENHWLSPENPSSPIQYYFKKEGSRTNFSSAHIHPRFQKHPGIPELPPFAEHATEHPSLFQKGEKKREQSPGQSLFNECVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P261</accession>
    <name>A0AAV4P261_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021559">
        <property type="protein sequence ID" value="GIX91108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P261"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10209" checksum="83C59021CBC66339" modified="2024-11-27" version="1">MRKYDTHKTRILVVNVQQRITGPTKKWHPYLETLSRLHPRPLNTFRKQRCYNSNLASLNAINAPEKKVCRSGGLWKNLRSGIALAHCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6S9</accession>
    <name>A0AAV4P6S9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">R1A1-elementORF2_718</name>
        <name evidence="2" type="ORF">CEXT_176031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004024">
        <property type="protein sequence ID" value="GIX91421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12754" checksum="7ACCD7D8A30B375E" modified="2024-11-27" version="1">MKRLTEKNMRVTVAQYGTPNTDSMFTKQEIRQVVRSMARRKAPGLDGITIELVEAINWGAPDILLSIFNKCLDLGLFPYCWKSAKLKLINKPGKDLSDPKAYRPYLSTPNHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDS0</accession>
    <name>A0AAV4PDS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Speckle-type POZ protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">spop-b_22</name>
        <name evidence="1" type="ORF">CEXT_792171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004535">
        <property type="protein sequence ID" value="GIX95582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="207" mass="24179" checksum="C61D4D1E2E19AA35" modified="2024-11-27" version="1">MEWRSYVWKIPNFSQLQPDKKKKKTFMIKSLTNDKQLVSISVFLTEKLSYEELIRFEFTDCNSLAKFTIIRLVLLDSVGNVVERVQDEFWSDDRCKQFPFSLPKRKLMANQSLYLPGDVLTLRCESAIATGINMEKVEKFYFGRCCDWQSNPTDVFCVEDEEHLSLSTRVLQENLKFLYSDGLLSDAILKTKTATFPVHKTYLLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PE60</accession>
    <name>A0AAV4PE60_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_395901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004359">
        <property type="protein sequence ID" value="GIX94308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PE60"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13306" checksum="DEDFB0A1B5A96C59" modified="2024-11-27" version="1">MQAAESLFSRSHAFWIDGSWLNVFRPPILSGFEKASVQPQKMFRVLRHHQAPRVRGEEKPPFGPRHDRHRVDAEHPHHLPAHLRVEGTAGSPRTTRSAPTSTTRDTSSTRHLVSVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGQ8</accession>
    <name>A0AAV4PGQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004662">
        <property type="protein sequence ID" value="GIX96572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8496" checksum="D35B919A3811BA4F" modified="2024-11-27" version="1">MADSQTPTQPILRYSIEKYLASKVTELQVAVVLNKNLIASSTIGRKPTIQTNLSNLSVSPVDQKEDDAIVDRVLKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PUY1</accession>
    <name>A0AAV4PUY1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">General transcription factor 3C polypeptide 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Gtf3c5</name>
        <name evidence="7" type="ORF">CEXT_538821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005090">
        <property type="protein sequence ID" value="GIX99740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PUY1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001002">
        <property type="term" value="F:RNA polymerase III type 1 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001003">
        <property type="term" value="F:RNA polymerase III type 2 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.160">
        <property type="entry name" value="TFIIIC, subcomplex tauA, subunit Sfc1, barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019136">
        <property type="entry name" value="TF_IIIC_su-5_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040454">
        <property type="entry name" value="TF_IIIC_Tfc1/Sfc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041499">
        <property type="entry name" value="Tfc1/Sfc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042536">
        <property type="entry name" value="TFIIIC_tauA_Sfc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230:SF5">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09734">
        <property type="entry name" value="Tau95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17682">
        <property type="entry name" value="Tau95_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel" evidence="6">
        <location>
            <begin position="12"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC subunit 5 HTH" evidence="5">
        <location>
            <begin position="152"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX99740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="437" mass="50764" checksum="077284BABAC45051" modified="2024-11-27" version="1">MDVKYNSKPLIVVEYPGTVLRVDNMSKTLGGKQEMFNVFKNPTKRLELKFRPDDPFCKCVHGDRFNTTNLVMKVIKKTKRKSNDKELPPKPEYKIEFLGVASTTYKFKSLADFQILPLSYDKEEKKYKSLLPQLVPTSLHSSSWLDEKIDLFVPPILFSRFDLPQLTYSEAPNKMKFQETQLPPNIIGRGRKRRAGYAVFASFEENKLHDKPKPEAVTQLNMYPLDIDVKAKVDELFKTRPVWSKNALQLRLKCDKSRLKYPLPCSAYYFTNGPWRTLWVRFGYDPRKDPASKQFQVLDLRINPSIPINEKGYRSRSSYYTLPNKTVLNHQRIATINTGDLLPTCKDDENIDDKYMETKLLACEYIPGQLPTARQCFYQLCDIHLESVQELIRENDGQEDICLEKDGWCLPGTIEKCRDLIMADLQKTAQELKDNET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2J3</accession>
    <name>A0AAV4Q2J3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">A disintegrin and metalloproteinase with thrombospondin motifs 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ADAMTS16</name>
        <name evidence="14" type="ORF">CEXT_38491</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005437">
        <property type="protein sequence ID" value="GIY02351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2J3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04273">
        <property type="entry name" value="ZnMc_ADAMTS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000001">
        <property type="entry name" value="A disintegrin and metalloproteinase with thrombospondin motifs 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.100.10:FF:000001">
        <property type="entry name" value="semaphorin-5A isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF293">
        <property type="entry name" value="A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="13">
        <location>
            <begin position="204"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="159"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="325"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY02351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="608" mass="69090" checksum="F284E774F8F8FF4C" modified="2024-11-27" version="1">MTDFSHEYAEIKANAFEDFEQENVIPVEVTEGRSSTNHLFEDSQETKRDLEQTGRDSSPSMASESTSVWRWKNRLAYWRLFQNISSRRERTVTSQEELENCLFRGKLRDRQPSAFALNLCGGMSGLLKTETSDYLIEPANRNASDINAVEKLHVLKKRSIRPDKNRGKQEEEGPNFFLRKKKKDTPEGSERGEKRRHHHRRNQRSIETLVVADREMVKKHGTENVTTYLLTVFNMVAMLYQDATIGNNVSVILVGLVLLEGDEPGLTLSHSAENSLSSFCQWQSTIHTSKGRQHDHAVLVTGLDICSWKDEPCDTLGYAPISGMCSKYRSCTLNEDSGLALAFTVAHEIGHNFGMVHDGQGSSPCRRKRGTIMSASLSGLDSSLLWSDCSRKDLAKFLESPRSFCLSNEPDSPDELQFPDYLPGQLYDADMQCRLQFGTKSKLCEHYPRKSEVCRALWCQRNGRECETKFLPAAEGTTCGKDKWCRKGLCIDRQLDNQKMIDGGWGPFSEWSNCSRPCGGGLMIRERKCDSPPPSNGGNYCKGEENEYQICGTQCSFWESPVSMPRILCTRQRRSVPGALHQTPRWNILQRKLFGSVHRRRMQSMLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q6R0</accession>
    <name>A0AAV4Q6R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_64171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005784">
        <property type="protein sequence ID" value="GIY05002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q6R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="9411" checksum="120AF4DC0B9D3470" modified="2024-11-27" version="1">MTVQMTRMISYQWLRPLILDKKVKLLSKEEKERIYLKKKKRERRKIKKENKLLFKDVKKQQAAQKINVQNTKGIKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QDN5</accession>
    <name>A0AAV4QDN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_316261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006120">
        <property type="protein sequence ID" value="GIY07504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QDN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11238" checksum="4732DF89D4F221B7" modified="2024-11-27" version="1">MLRVGHCSYVTGFLFLTDISISERKEKQVLVFFRKGLLNSDSFVKALEEASCVVNMSGKEGEMYLCSCYFAREILMSGSVTEICCLKGNVSMDEWDKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJ08</accession>
    <name>A0AAV4QJ08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_537491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006216">
        <property type="protein sequence ID" value="GIY08229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJ08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="280" mass="31339" checksum="AC770EDA4CE83897" modified="2024-11-27" version="1">MVLMASVPAVVRSCKQTVAVPQGSVACPHGIKTTVSIVVAQKSKFTRAATDAAKGSQPCLLDYLKDIEYKNVANASFDAEVSNIKDTHIPVYHRMKDRTLNRNGRSPRGHRRIVLNFRLPCGKALDPPRSFRALRSRDCAFCIERQQIPRRSADGSTFYRTRQYKRSGALTCFSKLQRHRLSSHMITTVVVVGEISLQCRCNIYLYFPMCWSSPLRLKHTSLLCSGAGLLGVFSMVGVWDLNWKLSEDSTWRCCSAGQIFGAAVQCQHIFSRDSLGSLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMF1</accession>
    <name>A0AAV4QMF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_380411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006543">
        <property type="protein sequence ID" value="GIY10605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13456" checksum="9740D5BCC363B8A5" modified="2024-11-27" version="1">MDELAQRNRCKVFLHLPSCLSETPLLLSRAFLDLVTSFSRVAGSHHQRRETNGRTLMADPNSQTCCITLPSRLAYSHFSKDNGSACQFFTHHIVLDERQTGRLLLPGTSPDERSKDVEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPV3</accession>
    <name>A0AAV4QPV3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_687741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006649">
        <property type="protein sequence ID" value="GIY11445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7557" checksum="A83769034026FD6C" modified="2024-11-27" version="1">MEKAKNPGMDANSPTIPPSQSSTLTSTYGSSSGYPTTASILYGSQLPYLPAALPYQVLQPSHPYFHSLSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8I8</accession>
    <name>A0AAV4R8I8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_607261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007444">
        <property type="protein sequence ID" value="GIY16956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10658" checksum="4C85984A91B24F93" modified="2024-11-27" version="1">MGIAEDVPQGNFKYLRSIPANGRILCLLLRSAYLAVKLMEELVRQCLCDSRRHIAKISTSVFSVIAPSDKMIVNNDAWKRKISFKEKFIIKKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAM8</accession>
    <name>A0AAV4RAM8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_401681</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007706">
        <property type="protein sequence ID" value="GIY19018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000193">
        <property type="entry name" value="Zinc finger protein 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY19018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="418" mass="47918" checksum="DED46FAF9A999F9B" modified="2024-11-27" version="1">MHIVLQCLMQELNFFIHGQNRSNFGVHACQTCGKNFNRADNLRVHERTHSKQKAFKCHYCTYGCLLNPYVLLKKLNIPDIEKYCGVEKTKQNLSIFESMECSNDVASKINTSKVDHIPLHSSLKLCIKCKVKGEKTLTPWKCKACDQPLCCQRSGERCFDSFHSSLNIPRKHVPSRMLKRGTCRQCKIKGKKNRTYWKCCLCDHPLCCQKNRETCFDQFHAVLSTNPENVSSERISVVRNTSGEDVLNDKNVSIDVTKKNKVESEILEESDDNTDHVPVKLISRKMCLHCKANGKSVRTSWRCRGCCKPLCNQTTGECCFQLFHSSDVEKTENLKLDSEKQQSAEQKNSMHVNSLPTIMSDDHLPLYTMVKRDCVYCKAKGSKALTNWHCNACGKPLCRQRYGNTCFYMYHSPTEVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RAX3</accession>
    <name>A0AAV4RAX3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_434551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007487">
        <property type="protein sequence ID" value="GIY17238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RAX3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10141" checksum="579A3E2B8BBD46BE" modified="2024-11-27" version="1">MMITTAHTGLNCMVGLLSHQLVAYQNPASKETSTASLVNRCDNADSPILWAEKCGGGHHILEGTHQPSQWRQSDVAVAHCTSQTEIVFTENTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCD4</accession>
    <name>A0AAV4RCD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_6661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007661">
        <property type="protein sequence ID" value="GIY18674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="250" mass="29666" checksum="76426A948DB76E3A" modified="2024-11-27" version="1">MVSIYFEYKNFVDDNSEKFNAVEHFPSICWKSYGMIDWPKSLEALMRIQSVPVMDRFELARMYQMRESMESLCNEMSQNQTGTRDYFNCILLRGLVQLERDRVPESPVKKTDWAMAAEILFLRSRRNSRFMSDLLSMFKPEEYEFYYLWDEDTFFIVMVQLLKSMYTAWGDTNYVNLLKKFWLASPVHLRENLKENELFYAKLKSVLEGRYEASINSAFEILDSWLADPGSICMKSLIFLPPLGLAFRVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RIG8</accession>
    <name>A0AAV4RIG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_111291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008026">
        <property type="protein sequence ID" value="GIY21510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RIG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY21510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12778" checksum="E153E47DE57DDAAD" modified="2024-11-27" version="1">MPSTQQKKSILSIHYHIILSPIDNYGVVPLTTARQARQQKKSKGNKMKTLGFFLETKLEIKDFPRKKLNAFEYEEHPTYKNPKWRNQFLEFTKPHDTKSTRNKTGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNP9</accession>
    <name>A0AAV4RNP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_294941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008329">
        <property type="protein sequence ID" value="GIY23888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10182" checksum="714DAC390AE89349" modified="2024-11-27" version="1">MGGSARIESLFGRSEALFGTAEPSEKRRPLIRRSSHNPGLSTDLSVRFPPHFERCSLPTLLTFTTFQCSWPLMLSPPFAHPNLECFLVAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWC6</accession>
    <name>A0AAV4RWC6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_769241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008445">
        <property type="protein sequence ID" value="GIY24752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWC6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13753" checksum="4E3A70EA82C1348A" modified="2024-11-27" version="1">MRFCGACKPYKGSNNKEGALQPLFAPMAIVPEGKTKRGPKNLSPRPYRMDYISLTPSGSSGAAKRFGGWGRECNSTPPSLGGISADDLFARADDLRRFLWPIPFLLFIFFFSLYSPVEKSGICLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0X3</accession>
    <name>A0AAV4S0X3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_698161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008645">
        <property type="protein sequence ID" value="GIY26216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0X3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8055" checksum="B70FA27EBD0CA0C8" modified="2024-11-27" version="1">MDEEERALPSQSGFRLVWQHLTHGHQEHRDHLSDFLSSLRYVRAGIHSRPWNMPSAACNCLRMDPDLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3I8</accession>
    <name>A0AAV4S3I8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_373491</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009016">
        <property type="protein sequence ID" value="GIY29048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="235"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="443"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="114"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="382"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY29048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="508" mass="55699" checksum="C8699F881B8E88CD" modified="2024-11-27" version="1">MIDLQHKNDRSTTSTSTTQENTSTTQEDTSATKSDSSSSTATTSSSSTTSRDTDNTESSSSSTPSSGSTTQESDNKNSKDTECTEEGESYVRYDFECPDDLVFDEDNNVCNWPNMSPGCESRSKSNKNESKSTTEGETSTTESTTGSETSEATTSEDKTSTTSGTSTTSEGSTTTTSGTRTTSLVLVRQGNQRLPPVRKQIQTIFNAKMKKVLFFDEDGWYCNAEELSPPCDGNSFKCEEEGFFRDPEDCTKYYRCNRTESGFRRERFQCQDGNVFDEEGRYCNAPELSEPCNGTSSTSSSSGTTLLQIKVQHLDQELLPILLHQLVPKFPLRQVPVHLLCVHNEDTGEFDRTDHTCQDGRIFDESVSYCNDPELSEEPCDSGSTTSSSTRGQTSTTESSNTSTGGSTNEETGTTESSSTTNAESTSTTSKPDQGNRRGGGGDPECTQEGFFRHPKDCNKFYRCVDFSGSGESFVRYDFDCPDGLHFDEVNSVCNWPTMTPKCTSESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBP6</accession>
    <name>A0AAV4SBP6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ataxin-2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_126282_1</name>
        <name evidence="2" type="ORF">CEXT_430731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009200">
        <property type="protein sequence ID" value="GIY30257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBP6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="69810" checksum="CDEA33CF661575D5" modified="2024-11-27" version="1">MNKRLGNSMAAMYPPNNRSRKTQNIRNIRNSPGPQVSRNLHQHSQGFHRVSSPAVAINNSQGNYKVNNSVSAAPCINQISPRPTPTSTPPAPRQPIPSNPVPSSTQFQQVPMTCVTSTVSSIAQPVRVTPAITPTVPQEENHKINGEMDKTELKFAPKPPRSLNLQTAANKEIRDAVAAQQAANKNIEKRNEMEKKTIQKGRNDKAEDLKRFHAKFKLSGDPKESLEENSTKPDSQPSGNGSVPLPPKHPIKEKLKEEERKIDIVSENRSSPDNPKNSTLNPNAKEFIFNPNAKSFTPRDPAQRFVPPTVQPPPRLQTQSPIMAMPQPHIMPGMPQTVFNMTPHYVVSATPVSMPMAAPPFTPAASVAAAPRFRKTMPLPLQRHEMAQPVHVQAATGQPILAQPTLSASQFTIQYAPSPGMLHHPPGHPQQLAYAQMYSLMPRVLTPQPVGMVPTSAAYGENPQIPTHVYMHPGNPGSIQHAMAPTNGGQHSAPSTPQSQTPSLHPAPSPVHQPPPSAGHGQPQTPNGHHSNAPTPQPVMYTHGHMPTQHQIHANHHSSSNQGHPFAAATYAGAPQPIVLLPQQPAPHPAPFTMPNHLHGQNPGSHVGTPTHVLPHGPLMIPTSPGLVHTQTAISTAHYVPHSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SN57</accession>
    <name>A0AAV4SN57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Denticleless protein homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Dtl</name>
        <name evidence="6" type="ORF">CEXT_570291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009831">
        <property type="protein sequence ID" value="GIY34912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SN57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="310"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY34912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="604" mass="66921" checksum="80036B4762C41157" modified="2024-11-27" version="1" fragment="single">CWAKDAHFSIGENGIYTPPLSCKFRRDYALDLLAVAREDGNIELLNTEFGNGAQICFNAHNNAIFDICWMPDNFSLITASGDFSCRLFDVETCKMVSAYQGHLATVKSVDICSHQSAIFASGSRDGNICIWDKRVNYGSYRQKPSILIHSAHSHNHIKSNSKKHSSSNCVNSVSAVAFQDEYKLASVGVADGLVKSWDLRKTYVCNPNRLPTPRYQMKCGESNSKTHGYTSLTFDSRYQKLYACSTSNEICQFDFHSHNDKVITYLGFKCNSYYVKLALSWDDQYLLCGSSDYKAYIWKTAKPGSPILELSGHSAEVTTVAWSPHNPTKTTCGDDNRTLVWNLKNEDEKVDINVNEVVGSTKVFSIDNDSFKSTTSNELSESFMTSKSTSVSSPTTVIRKSSKSLPHSIKNEAKVRTQSITSFFSPVSQTLSQSRTDEKIVHQKLLQYIVPVQNHHHIFHSDIDFNSCTQSQLQNIGEKVNTDDYSPEICINEPHSPEIHGKSDPSVCATPVSSTLQRSPCKLRNNHVPTEMLLSPSKSSPHGKENNSIAKLSSDKSKPNGQLKRKVSELTGANICKNHPHGCGKTKGCSSCGKVIVTSPSTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWM4</accession>
    <name>A0AAV4SWM4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TP53-regulated inhibitor of apoptosis 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_195293_1</name>
        <name evidence="4" type="ORF">CEXT_64871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate(in) = a 1,2-diacyl-sn-glycero-3-phosphate(out)</text>
            <dbReference type="Rhea" id="RHEA:36435"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRIAP1/MDM35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010354">
        <property type="protein sequence ID" value="GIY38773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990050">
        <property type="term" value="F:phosphatidic acid transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007918">
        <property type="entry name" value="MDM35_apoptosis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403:SF1">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05254">
        <property type="entry name" value="UPF0203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY38773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9285" checksum="BDB68E272A217E79" modified="2024-11-27" version="1">MESIGKDCKELKQLYEACFNSWYSDKFLRNESGDISECDPLFQEYQKCLKSAMKKNNVPLWELNGGMLRNPEKKQSDSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXJ1</accession>
    <name>A0AAV4SXJ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenomatous polyposis coli protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_92251_1</name>
        <name evidence="2" type="ORF">CEXT_323901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010207">
        <property type="protein sequence ID" value="GIY37704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030877">
        <property type="term" value="C:beta-catenin destruction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045295">
        <property type="term" value="F:gamma-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001708">
        <property type="term" value="P:cell fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007026">
        <property type="term" value="P:negative regulation of microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007389">
        <property type="term" value="P:pattern specification process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026818">
        <property type="entry name" value="Apc_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009223">
        <property type="entry name" value="APC_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12607">
        <property type="entry name" value="ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12607:SF12">
        <property type="entry name" value="APC-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05923">
        <property type="entry name" value="APC_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="749" mass="82900" checksum="9510117101434076" modified="2024-11-27" version="1">MIKILKKHVVQLLGIKGILPRPTMNSDSSKQLDDEVKVYCIEGTPLMISSASSLCDLREVGNTEQTSQSLISKPPFSKKPCFSTSSRCSNISEEDNEKRCDKPKSIANEMLMSNYVEKEELCKNDEIVNLEADTAFTRTSSPLMFSRYSSLASLNSFEKQSFADDKSVSTFSNLTSGIISPSEIPDSPGEVMSPFIQKISNLSALSILTNSTRLSGTLVQHKKELISLANKSSVQINYSITTEDTNFEQSGNNHLLTSNANFAPQHNCINNFSNFNDCTVGNSTNQVEKNNAIGNKVLPKCEDKGTSTSEDFNFLETESDSQEFKEKSNEIIYPQENESADYSKDNSDDECDALLEECILNGMPRKEDLVLNDSKKSLNNSFPEETGSLTKETTEEQNCSYSDNDISDDDILDECIQLGMPQKVSKNVQPIVIAKSSALQVTPLSKGCLNSSFSESSVFNQANLSLKPAISNHQSLQKRPNVLKSVESPAYVENMPFHPCVKLGTPKTLYEETNVNKRNISSICTSISSAENQQRKKKTEVSKCDDDSNNDQNGMLIQGCIQLGMPRNQLKSYENLKVMKLPNTQLGYRDNCPDGISDDDDDDDILSECIKAGMPDAEILSSGPQYTEQTKSRHLKLPSQRKLTAAEDRAMYLKKYCGGNMQQEFLPNASELIAVDDSMCVYRTEDTPLLSPTASISDLSTLSFAEEKLCQESFLNNSRNSDCSSESEDDELLLQCIRSGMPGEKRAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZ90</accession>
    <name>A0AAV4SZ90_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_102161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010291">
        <property type="protein sequence ID" value="GIY38336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZ90"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11087" checksum="3F88F9651FFBCD03" modified="2024-11-27" version="1">MNATIVDNESNSEERTPTVGQEMDLPNNIGEIMSIALEQYNELVNLTDTRDLKSAAKQAFRKRATALLKIITHQSNLIAQMEERRTRTEEYSSGLQTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T609</accession>
    <name>A0AAV4T609_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010577">
        <property type="protein sequence ID" value="GIY40205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T609"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17435" checksum="5D2F356571611314" modified="2024-11-27" version="1">MPSSLFLDHLYETENPNNFTGRAFLRLLSTSQVSVQNRESREAKLCAMKLNKDKNTQGNDFSHGIADSVSYALGSIQTQKSNFGSGIINSNIEPRAWEYSNPVTYSSLTYNACNISTTTTSKKSTVDCNEHTPDKMSNRNPSLFKQSMDKFFLLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T8X9</accession>
    <name>A0AAV4T8X9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Arpc3</name>
        <name evidence="7" type="ORF">CEXT_678401</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010709">
        <property type="protein sequence ID" value="GIY41372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T8X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY41372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18363" checksum="AD95D9EA7A4FDCE9" modified="2024-11-27" version="1">MPAYHSQLKSTQLIGNMALLPIKTQFRGPSPRGDTEQDDIIDEAIYFFKANVFFRTYEIKSEAGTLQRCSNKNQGTNEMYSLAIAKFDIPGEYGFPLNAVYAKPSSPSEADLMRQYLVQLRQECGARLCEKVFDPETGKPSKWWLCFAKRKFMDKSLSGPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TBG1</accession>
    <name>A0AAV4TBG1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_378533</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011054">
        <property type="protein sequence ID" value="GIY43903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TBG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.300.10:FF:000002">
        <property type="entry name" value="Multiple epidermal growth factor-like domains 10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.300.10:FF:000041">
        <property type="entry name" value="Tyrosine protein kinase receptor tie-1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.300.10">
        <property type="entry name" value="Tie2 ligand-binding domain superfamily"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042635">
        <property type="entry name" value="MEGF10/SREC1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043:SF8">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="609"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="2"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="529"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY43903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="784" mass="85416" checksum="9C55F17AA5CDE375" modified="2024-11-27" version="1">MWGKSCSQNCSCMNGAKCLSATGQCICTPGFIGQSCESPCPEGKYGQDCQEDCDCRNLAECNAATGACNCTLGFKGKKSCDEICDGGTWGHYCSMKCACVNGANCLPSTGECICAASWKGEICDEHCDLDTFGRNCEEKCDCRNGASCSPVNGICDCTPGFKGDNCEQECENDSWGYYCSEKCSCQNNATCLPQTGECLCADGYQGLLCESMCSLGSYGKHCEKKCDCNNGADCSPLDGFCNCTAGFQGRSVRNPVKKAFGVIIVQKNASARTEVSAIPQQENVPALQASLVRSARQNALWEHLDPCVMANASARMMASAIRSQESALVPQVTKACIVKKKCQEGFYGLNCEMECLCNSTTAYDCDFATGFCSCLAGWKGNFCDEPCDNYKWGAFCNNTCPCYEGISCHHITGECFCEPGYQGYNCSEKCPSGTFGVGCEGACPPCPIKDSTCDHVTGWCDCPPGQTGRLCRKTCPEGTWGKGCSKVCHCKFGQCNPVNGSCICPPGRTGEDCSIGTECSNGTFGLDCMQQCVCHNGGECLPHSEICKCKPGWAGPKCTEVCPLDFYGDRCSKQCSCKDRFICDPHIGCVKSREEAMGLSILNSQIFQISGLLTAVTVVGVIVLIIGCIMCKRKRKNTRLELFALSEKKHNFSVKSECRSKVEESNCDEENHGNVYEEMNRPDFQIYENVELKRNSPFSHFEFKFPETVPPDVVYENTEDCRRKLVTAEDIQEAHSAFYDKPKSNPVRVNLQDNLHVYENATYDLHVENTYVNTSANFAGKNVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFG7</accession>
    <name>A0AAV4TFG7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_61571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010986">
        <property type="protein sequence ID" value="GIY43520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFG7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21276" checksum="75942D10FB83EE51" modified="2024-11-27" version="1">MRRARTKSRTTSQSHLVQVYLFDREAYLSTLDSYWSDLESSHVLHWMKGATTRPGRRGLEKSPCDVIAPAGSGKRAPILSNATSVLGIPQTAIRSRGPLFNHALCLQHRIISPEDCLFSLSLFPAFLKVSPLQAENKRGFGPFFLHAQTFDWEKFGGIIDGVSLPNEIRLGFIMGIVISTFRQLLFFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIY9</accession>
    <name>A0AAV4TIY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_343661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011193">
        <property type="protein sequence ID" value="GIY44757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="190" mass="22301" checksum="3F6B9C36F9A9754A" modified="2024-11-27" version="1">MSYLCRKSYLCRMSYLCRMSYLCRMSYLCRMSYLPSELSAKNYLCRTSYLFRKSYLCRKSYLCRKSYLCRMTYLCRMSHLCRVSYLPNELSLPNELSLPNELSLPSELSLPNELSLPKELSLPNELSLPYELSLPNELSAERAISAEKSYLCRMSYLCRMSYLCRMSYLLAGDFWGTVSTPNELFSLNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TR03</accession>
    <name>A0AAV4TR03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ras-related protein M-Ras</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MRAS</name>
        <name evidence="11" type="ORF">CEXT_751011</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Lipid-anchor</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011618">
        <property type="protein sequence ID" value="GIY47752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TR03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000080">
        <property type="entry name" value="Ras-like GTPase Ras1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY47752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="244" mass="28765" checksum="01EF75DEA2CF52D1" modified="2024-11-27" version="1">MRKQKQNRISHLFPIPRFYRTIWGKIIQIYEDCFLAFVKKCEKIIKMSKPPNENLTTYKLVVVGDGGVGKSALTIQFFQKMFVTDYDPTIEDSYIQHTEVDGQWCILDVLDTAGQEEFSAMREQYMRKGDGFLLVYSVTDKQSFDNIRHFHTQILRVKDRDSYPMLLVANKVDLVHLRKVTEEQGKELAVCLKIPYIETSAKDPPLNVDSAFHEVVKIIRNQPPLQDKRRRRFWFRRDNRCVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRL3</accession>
    <name>A0AAV4TRL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_52701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011571">
        <property type="protein sequence ID" value="GIY47382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12100" checksum="8C7C0C7BA4965242" modified="2024-11-27" version="1">MVVRLSTHRTCLGSHSVLSRLTLRANKAKAKSTGACKQSRKNHIPRKTMASWSQVQVVFDGSPDVKTRISQMTQQVPGVDNGCREAKPGNGIITLVSSRPWKECSSAIPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U1E9</accession>
    <name>A0AAV4U1E9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein 98</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TMEM98</name>
        <name evidence="13" type="ORF">CEXT_628531</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Extracellular exosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TMEM98 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012131">
        <property type="protein sequence ID" value="GIY51606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U1E9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TMEM98"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32510">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32510:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004550"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011024"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00014380"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY51606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="242" mass="27140" checksum="24D381F77DC8E479" modified="2024-11-27" version="1">MAMEAVVLAAITVLTIVFVASLFALIMVCRHKYCRPFDLLSSQFKDARPEINLISNEDCTDMELDDVRLHPNIEEILTDEQWVDDATGLIPHCLAILKKCHHLTERLVAMMMTRVPQQSNQDLNEIIDVAKKISPRVDDVVRAMYPPLDPRLLEARCTALILSVSHMALVIRSVCQLRTCNWVEAALIDMEENLQVLREAGIALEAAASHQINGMSTLECNELNPSEFISGNTLLSRNSNQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U224</accession>
    <name>A0AAV4U224_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_101231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012168">
        <property type="protein sequence ID" value="GIY51848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U224"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9380" checksum="140F56B6606C9EBE" modified="2024-11-27" version="1">MRYYGQQNRYLIHVIMSNSILQMNTHSVLRINPESIVRSTLKLVVEIKPKVPYIKRRKMTTPKQNPFAYEMIILRFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2X8</accession>
    <name>A0AAV4U2X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_499901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012186">
        <property type="protein sequence ID" value="GIY52017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9473" checksum="EEB6D9D9736BD2F6" modified="2024-11-27" version="1">MPCKKDANKSVGRLPVPPSRKVGKSLAAHKESDALLCPGVYKKEPCRDNVCLGNSTNGVGLRKQKGSLRSCTNGWAQTAEYGTMMRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCS0</accession>
    <name>A0AAV4UCS0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_767671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012658">
        <property type="protein sequence ID" value="GIY55616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8344" checksum="2E8FB4BB4D7013E9" modified="2024-11-27" version="1">MYVKRNPLKLTRWVRAKIKNESTTEECKKKPQNQCRHDCQVLLTTQCNHPIVSAIHKNQRRSTMEEQEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UQ40</accession>
    <name>A0AAV4UQ40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C-myc promoter-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DENND4A</name>
        <name evidence="6" type="ORF">CEXT_580021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013245">
        <property type="protein sequence ID" value="GIY59825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005112">
        <property type="entry name" value="dDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023341">
        <property type="entry name" value="MABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF30">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN CRAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00801">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51498">
        <property type="entry name" value="MABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MABP" evidence="5">
        <location>
            <begin position="38"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="UDENN" evidence="4">
        <location>
            <begin position="178"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="719"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1035"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1454"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1070"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1085"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1105"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1124"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1146"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1160"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY59825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1485" mass="166708" checksum="2AF14345D7BB35D9" modified="2024-11-27" version="1">MDDKRVADYFVVAGLQDNASPLDEFSRDGNVPKSIHPLVPITDVTVIIRSQGETVPKGFTCIEYTPLNFPADLNHGSIRSPNIYFCYRRGRDKPPLVDIGKIMADSEVVLTTACGRSANVNNSGSKTFITYRRAPENAPCNQLVVTDICIILANKGENAPRAFCKIDKNLNKGCGSDVFLCYKKSMNRPDLLSYKPGILGRFPLDDYETFPLPPSVPLFCLPMGANIECCPKRLNNRNQYFLHLFSLHIQQKRQTNPYVCYLDGLSFDTFEKFLRYLHRMSISGPHRVPLERIISHFMLEVPFPSVQRPRILIQLADYTITLAQPGDTQLPLTGASFIQLLKNLGPDNCLKILLFALAEQKILFHSLRPDVLTSVAEAVVMLIFPFHWQCPYIPFVSSGFVRCFMCSSAIFSWVDSRYFDLYDPPQDVTCIDLDTNSFLFLMKKRHLNVKLFSKRPARILRNTLQTLYGKLASVRCPPSTSLLLSNNSAQIDYDFKAKKNERQLELEIQEAFLRFMASILKGYRSYLLPITTAPTIGTTDPNSLFDLSERSFVSDKDVSLAFFDECTERIDSSENSDSKFLEIDESQTSDRTVFVAPPEPVGLPVGLEYRYKQFGMLKPQLFHKNPAKSLLNLIAQASPIPNSPMARRSKQEIRSAQKIARKHSETPVMWAKCLVGYCVSLWFIHLPSFAKSSPSKNSALRLAFDLLVQIQKFKICQPDEVCYRVLMLLCGLYSQPTLAVKVLFEMKRHGVQPNAITYGYYNKAVLESKWPAADTSSTLMWNRLRNVIMGIAQFRQGLKNKARRSLSLCSETELDRLSRTSTESSNPDDMTLVRIGNPAEFVPDLIKLADDQNNSDELSDHCDKQKCDGAKCSVARRLKFEEIDFSVADDFRNRVGSIVKSSASSIGTLSQLQECAVDSSAGILMTSRTSLLDEVKLCDWETETRKRHKSAGDCNCHTSCYLRSPNKPLNEVVEEGEIKTPFLRSYSFGNDAQIIRKIKATKEITEPLAKWIESPLKKGLFDKKREDKEKVSKNFGLTRCDEEPESEQDTSGISSVSKLLRPKSPSIPIEKQRKISEESKHSVISSLSSEDGSTSSAADDKNTDENLSTSSQDFLESFRKKQGNKVSRSSTFHSGARNSVPKLKPRKEGLAKLNTDDTVKSMSRSSTLPVSPRVSHSSENDLSGSPFGISRLTSRHSEVLFDSLKSAVTSVSSKLNEFRSSLSASNTPTKVNAFSSSSQHDIDLILYDDGELGGLTYDGYRISMDFANLNDCGTSIFSPDHGRERTPGRFDHRGSLPHVVSAPVFSSQVFEMFEKQNVATTDNSGSQKTAVDITMTTCSRCFTCSSLLYDEEIMEGWCADESNLNTQCTFCKAKLVPLLSIFVEDFRWSDSEENDTSSTHSTESICSISLNSHPDILANRPKPLMENDKVTTNIDSNHNAFILLEDELEYENRPKSCKGNNAKNQLDENENPSLLKQRDTEIFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4US68</accession>
    <name>A0AAV4US68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_718581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013375">
        <property type="protein sequence ID" value="GIY60761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4US68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY60761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="151" mass="17309" checksum="5988F9336F283B39" modified="2024-11-27" version="1">MRPPKKDGTLSNEHRVSFLSLVGLQSTGNVTRLCKDDPKTLHGLHEIEELFLLEKLKEKLQFFSYHQLTPAHNSLPPYAPSLYLALVSSGDENPGKYLPSIGHYTKWKTRVRTLMRYYRSLSLFSFLYRFGSSPLGGGQKPYKMLSTSWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V3T4</accession>
    <name>A0AAV4V3T4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial enolase superfamily member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ENOSF1</name>
        <name evidence="5" type="ORF">CEXT_17331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013893">
        <property type="protein sequence ID" value="GIY64559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V3T4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme N-terminal" evidence="4">
        <location>
            <begin position="26"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY64559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="20952" checksum="E6A05D5DDF68A880" modified="2024-11-27" version="1">MEAKIENLEVKDVRFPTSLTGDGSDAMHTDPDYSCAYVKLTLSDGTCGYGLTFTIGKGTEVVVTAVKALAPLVVGKAIQSIYDDFARFWRDLTSDSQLRWIGPEKGVIHLATAAVVNALWDLWARREGKPLWKLLADMTPEQLVSTIDFRYITDVITKEEAIACYPLGHPTHSNSNSKAPVYARETYHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8Z7</accession>
    <name>A0AAV4V8Z7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_346911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014085">
        <property type="protein sequence ID" value="GIY66153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8Z7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10863" checksum="BA762FC0F5065394" modified="2024-11-27" version="1">MHAYTGVREHCDRVTIERSNIVVTTSSLRDNVHRVTLLRGMEQKRGHRLGFATLPNGFFPSQMEFVFLPFYCRPIIPPFSLLPPHGKQLVKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VAR3</accession>
    <name>A0AAV4VAR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Stk31</name>
        <name evidence="7" type="ORF">CEXT_349621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014214">
        <property type="protein sequence ID" value="GIY67212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VAR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000018">
        <property type="entry name" value="Serine/threonine-protein kinase 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="6">
        <location>
            <begin position="145"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="718"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY67212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="968" mass="111278" checksum="929259A53484523F" modified="2024-11-27" version="1">MNNQTTDIYVSNVPRNTKEDELKQLFSQYGEIKDVLCRRKEDAFGYAIIKFLFKKDADRLLKTVGEVIWKNHILPIKLAKRSEHSVQNGNSGLENKLNNFSNGRNPYIPEPKYSNTDYGHFYPPPYQERLPYSQPMMLEVLPERKPSLRRIYGALFSEDKLWYRCTVIHSALPNKPGMCLVQYIDYGNKEEVIYRNIVEIPECLQKIPPLVTKFTFSNLICDNPSSKKSCLHKIINRRLTVCAYLSNSNTDYSVVKCFCDGKDIIMETINKGFAQLQTHVWENENKLSSTWNDNGYCRPLNIPKSHEAPVVNGSLSNDKKLQKPKNNDKNQSKIKEEQKNEQHVCNGTDEKLQKEDFLPKMIIKRGSELNGILKKNSSEKIPKEPNLNQPTTYTLDSVLPNLKLINNIRSLVSQSSDDSILTSAVDLLKNETNTVECSEMSNKCTDDTYKEYKEAVKKIQNSQDKKDILPLLKSERDSCRAILLKKLEEYLNSFDRTILERKEKIQKVITDLESNSNAWMNVHLHKKPESVEELIVEYNKEERWTLVSKTRADSNQVHKQFMNILASLQNIDKTTSFSNQLNKSIVELGKALDEEIRTLTLNKEDANFSIIQCLLDFLDIHKDKIDKMCDLYESHSAVYNELKQLPDIKIVLKEDNTASSSQIATVRKQLHQALLKEDSLKEILANVSCFHFPELLIEVPELNLNNLLKNKLLKSWKPYYFKNFGTGPRGESSYVSCLLDEPVTIKEYSFENNEDLNCFLLNAALWNEIKSNSLLKSKALFLKDEKTVCAILPALSNTLLGITPFKSTPDGEKSCRLLRQILIGLKDIHQEGLVHNAVHPLTVVIEDEKALLDFCFDSHYLDGKYNLEGINFQPPDNKEKCRDETSDMYAFGCLVLWNSCFPNLLFTTTTDGVPNVTAFREYYRRIVLPKDYALLCALLSPNPAERPSAFTLLARSFLSKYELFIQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBM8</accession>
    <name>A0AAV4VBM8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Saposin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PSAP</name>
        <name evidence="9" type="ORF">CEXT_229031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014263">
        <property type="protein sequence ID" value="GIY67637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBM8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.225.10:FF:000002">
        <property type="entry name" value="prosaposin isoform X2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.10">
        <property type="entry name" value="Saposin-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003119">
        <property type="entry name" value="SAP_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007856">
        <property type="entry name" value="SapB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008138">
        <property type="entry name" value="SapB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008373">
        <property type="entry name" value="Saposin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011001">
        <property type="entry name" value="Saposin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008139">
        <property type="entry name" value="SaposinB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051428">
        <property type="entry name" value="Sphingo_Act-Surfact_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11480:SF3">
        <property type="entry name" value="BCDNA.GH08312"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11480">
        <property type="entry name" value="SAPOSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02199">
        <property type="entry name" value="SapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05184">
        <property type="entry name" value="SapB_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03489">
        <property type="entry name" value="SapB_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01797">
        <property type="entry name" value="SAPOSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00162">
        <property type="entry name" value="SAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00741">
        <property type="entry name" value="SapB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47862">
        <property type="entry name" value="Saposin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51110">
        <property type="entry name" value="SAP_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50015">
        <property type="entry name" value="SAP_B"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Saposin B-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="7">
        <location>
            <begin position="56"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="7">
        <location>
            <begin position="143"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="7">
        <location>
            <begin position="233"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="7">
        <location>
            <begin position="324"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="7">
        <location>
            <begin position="423"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin A-type" evidence="8">
        <location>
            <begin position="508"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY67637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="60727" checksum="7E7EE89D7F11B2A8" modified="2024-11-27" version="1">MRLPAAVASECKQFVDENIDFLMNTLVEFLDPQKVCSILKICPAQIVLEAPKISVNNVECDLCKQVVNKVGDKETEEQIMLAMEKVCGDLSPSITTECEEFVSTYGDMIVALLVQHIEKELVCPKLQLCPAQIKLEAPKSSVNDVECELCKEVIAKVEDIVKDQKTVDKIEAALDEVCSRLPSSIATKCINFVNTYTDMIVTLLMQELDPAMVCAELKLCTAQIKIQKPKDVKDLKCDLCKTVVSEVEEMVKDKKTEDKIEAALDEVCSRLPSSIATKCINFVNTYTDMIVTLLMQELDPAMVCAELKLCTEEVEFSENQSKAKGMECQACQYALHFLQELLMGNETQEEVKNALKSFCHILPQQFSENCESFIDEYGASLLVLVAQEIDPSVMCLKMQLCPSKELIPQLKGEASEVALNHFLVDECSVCTTVVDYVDKLLEEDDVDKELTKLVEKVCTVLPASYQEKCASTLEAYGPYILQMIGQMASSKEVCQEIDLCPRTRGQVHLIGGSKCTFGPSYWCHSAAHAAACKAEMYCKTKVWEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKL9</accession>
    <name>A0AAV4VKL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_47461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014673">
        <property type="protein sequence ID" value="GIY70490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17259" checksum="71730665344E7201" modified="2024-11-27" version="1">MSLVIFSTNNLAFSTNNLAFSTNNESRDFPYQQSRFSLYQQSCFSLPTILLSLLTISLVIFSSNNESSDFSTNNLVFSTNNLVFSTNNLAFSTNNESRGFLPTIFFSTNNESLVVFSNNLAFSTNNKSRDFSLPTMSLVIFYQQSFFSTSAFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VKT2</accession>
    <name>A0AAV4VKT2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_245561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014724">
        <property type="protein sequence ID" value="GIY70812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VKT2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10935" checksum="4E8352DBD69B745E" modified="2024-11-27" version="1">MFLAPQNKRNFEESCSDDGVRTFNITHDIDLANYPSFPNRSETDKDSLRSLYSKESSNVLNLDKRSLTQDNLSLYQKEDEPTAVQMGFKVAAILIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VU36</accession>
    <name>A0AAV4VU36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_3711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015141">
        <property type="protein sequence ID" value="GIY73927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VU36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="199" mass="22752" checksum="E07E906ECAEAA093" modified="2024-11-27" version="1">MKVFMGYRSYIEREKRCEKEQSSGSEQTRHKAPSVVLSAYGHRPHREKEDAKNRALRDPVTDKCGLTEDLRVTDTDDKNSKAKCSVVSVDIVYMREKRCGARRFAGFQRQGSDGGVQERRGVEQEQSFGIPAEKRSNGGFRVIDTDDKSEIMFAGYRSYRERRGVSKNRALRDSSRQGSDGGFRVIDTDDKRISKERVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWA2</accession>
    <name>A0AAV4VWA2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_397001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP = 3',5'-cyclic GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13665"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57746"/>
            <dbReference type="EC" id="4.6.1.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01015217">
        <property type="protein sequence ID" value="GIY74408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY74408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20582" checksum="08D09C247A72B759" modified="2024-11-27" version="1">MRDLRHDNLNSFIGACVDPPNICIVTEYCAKGSLKDILENEDVKLDNMFNASLIGDIVRGMTYLHESQLRSHGNLKSTNCLVDSRWVVKIADFGLHELKFGSDSGDDDSTDFEKQCATVFLYPFIKRVKETAECGKRNKVTKSGIFANFGQDKSKNIILDKGHNDNRPIHSPNCLYQCLYIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZ79</accession>
    <name>A0AAV4VZ79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_709101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015295">
        <property type="protein sequence ID" value="GIY75046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZ79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19081" checksum="070CBA3E2961522D" modified="2024-11-27" version="1">MLSSTPDRDSRATVLLFFCWIPKPVTFTRNSFINFIVLLVIQKTGAPLLHKSPSAAKNTHPNHLNLPKKTDPPLVQEERRSHPLVSVEAQQLKPGVSSKECPPDMEKASPEQSTPSIPRPFLKIPLLSRAVGTGVTNSVCREREPPPTTRSQRRSSSNGMGLFVPIVLPLYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0J8</accession>
    <name>A0AAV4W0J8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_559891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015341">
        <property type="protein sequence ID" value="GIY75434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0J8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11296" checksum="A0D67979342FCD92" modified="2024-11-27" version="1">MAMNLYIWKGCKLLEIATSLKARLLAKKKVSEFNILRKKFHADKDKLKIEFPKKIEVPEDSEEEWCKFCLGSELSSAIYKHKNSCSTSDNLIEGASTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W8E2</accession>
    <name>A0AAV4W8E2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_591921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015762">
        <property type="protein sequence ID" value="GIY78493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W8E2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="20501" checksum="706C07A3F37C2A13" modified="2024-11-27" version="1">MVTITEPATAEVDSNSCGSLIATVPWLQSYVPPFPGRMIDPFTQAPILVPQTASMVPVIHQVPVNLNGYQAATANGFHQNEHLYSPVPVLQTAVAHQPVVPNGGTLVPVSNYSTYYNSYAAPLPQIVQSPGYEMNGHDYGADYVYQNGHEILNTLLARMEYRIRISFTIQVMQILQCLILNVHLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WG46</accession>
    <name>A0AAV4WG46_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_547341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016056">
        <property type="protein sequence ID" value="GIY80819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WG46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13485" checksum="BA161B3A40F65469" modified="2024-11-27" version="1">MGCHGDLSHRRYELLQIYGEHKSPASETTNLVEQRQTFPSTPVIRETILVNDSFTEQHNNCLSYSLFNEGRLLFIRQRDFLLRRVGLERVLRSVGFVISAPRTELWSLFLGVLFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WK10</accession>
    <name>A0AAV4WK10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016315">
        <property type="protein sequence ID" value="GIY82982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WK10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13326" checksum="79558AA5E26BDFBF" modified="2024-11-27" version="1">MGWAIREQVSVCAFSADPLFSSQKVTWGKECLLFAPVIQEFRKVTCIPEVLSYGTLGEKNPIADGRCTFLGRNCLIFVASKLIFVILWHQKLILWHKVNFVASKLIFVAKVNLWHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WNU3</accession>
    <name>A0AAV4WNU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YLPM1_1</name>
        <name evidence="2" type="ORF">CEXT_676261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016531">
        <property type="protein sequence ID" value="GIY84595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WNU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15785" checksum="7BE5A48E799FEFDF" modified="2024-11-27" version="1">MYQAWQWGGTTAAASPTTAGYVQPAGTGQVATPQWPANYNQYAAVTPEMQQQWVAWASQAQYAYGGAMPVAGQVPTTTANPFSNYPDSQSQSTESNTQASSEKPKNSSDEGKSILYFGWTWINKKQEKFHNQLFPHVSILEIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WW08</accession>
    <name>A0AAV4WW08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_377961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016800">
        <property type="protein sequence ID" value="GIY86468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WW08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13432" checksum="6D7DAA9E4AB3E5F6" modified="2024-11-27" version="1">MYVSWISWTFAYFGQVEHLCTLDLLNIWVFGPVGHLCLFGPVGHLRILDKLVPWISWRFTYLGTVEQFCILEQLDIYISWTSWTFNYLGPAGHFLFFGLVGHFLYLDQLDIYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXV7</accession>
    <name>A0AAV4WXV7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_320151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016958">
        <property type="protein sequence ID" value="GIY87627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9481" checksum="C24B886CEA4200BA" modified="2024-11-27" version="1">MSKQIPSSTIIWTSIFKIRITSRECQTDSHTTANNALWLPARGASIQQLNSTLCDPVDVLQKQRLNPSLANLGKEAASAETVNLNGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0G0</accession>
    <name>A0AAV4X0G0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_120651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017027">
        <property type="protein sequence ID" value="GIY88172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0G0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9853" checksum="DFA9EA59444B10E4" modified="2024-11-27" version="1">MDMVAEHESEWMAESELSFRDENVWCQTRLAKRQETMGVVKSVFALKREPGLPIINECLTEQTRGEDIGHCFRRDIGRIPGNKTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2Y0</accession>
    <name>A0AAV4X2Y0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysosomal aspartic protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AAEL006169</name>
        <name evidence="3" type="ORF">CEXT_276571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017141">
        <property type="protein sequence ID" value="GIY89023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2Y0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY89023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21357" checksum="714ED7EABA4AFEF8" modified="2024-11-27" version="1">MTLDGKSFDFCPEGCEAVADTGTTGIAGPVAAIHKLNTQLGAVSIGHGQYRLDCSKIPMLPKVSLKFGGKIFELEGKDYVLQFSSLLADRWQSRPQSEGLQDLYQWLHWHEFIRAPLGYRQRIPGTLLHRFRPRQKKDRLCGVYLMAIRPGGLGGLDAKCYWTSCKDTKYQRISQRHVKFLKGHISLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4A1</accession>
    <name>A0AAV4X4A1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Polr1a</name>
        <name evidence="8" type="ORF">CEXT_663711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01017077">
        <property type="protein sequence ID" value="GIY88594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4A1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY88594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="41823" checksum="A9D19AC370BFC17F" modified="2024-11-27" version="1">MAKIQLTIADEEVISKCTGKNLNEKYNNAYHQLQKNVNVLFDSESHKDRNRISEGIRQILEKKEGLLRMNMMGKRVNYAARSVISPDPYIMVNEVGIPLIFAKKLTFPEPVTFHNVEKLRQAVINGPDVHPGATFLEMEDGRKLKLTSDAAKRQAIANNLLIPHLQSSVKKKGKGMIVHRHIKNGDMVILNRQPTLHRLSMMAHKARILPGEKTLRLHYSNCKSYNADFDGDEMNCHLPQSYPGQGECFGIASVNHQYLVPKDGTPLGGLIQDHIVAGVLLTMRGRFFQKNRYQQLVWSAMSSYHKRLKLLPPAILKPQTLWSGKQIVSTIILNLIPEGKIPLNLQGKAKISQKNWKTHPAGMACRWIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X956</accession>
    <name>A0AAV4X956_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_791491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017384">
        <property type="protein sequence ID" value="GIY91134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X956"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12515" checksum="5E20DF80A72C99C8" modified="2024-11-27" version="1">MKAMVTFSKQSRAKIRISKVGRRRKIFHVRDLNFLRPSLPPPSLNPVFPETFFFAPEFSSGKAALFPNWMEFNIGVFRMGILGKWNEKSELNIVFAVEKGSDHAPISVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9A6</accession>
    <name>A0AAV4X9A6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_689781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017327">
        <property type="protein sequence ID" value="GIY90555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9A6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11441" checksum="1F70C023C317CDEE" modified="2024-11-27" version="1">MCLYFCQEVPTPYLTTLHAPINKLCMVHRFFHEYLNYLGKNCSTTHGIYLANDSSSFMRIATLTILGGRLVTNGWQRMVVHTSGQNVYLDWSQYRCPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAE4</accession>
    <name>A0AAV4XAE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Roundabout homolog 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Robo2</name>
        <name evidence="4" type="ORF">CEXT_591691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000117">
        <property type="protein sequence ID" value="GIY92241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000053">
        <property type="entry name" value="Roundabout guidance receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="106"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY92241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="23680" checksum="F4C6AE17188EBB00" modified="2024-11-27" version="1">MSLEIRVPIAFQQKISESSPSTCPPPSARVRPWSAPPKRDTGTHGPVEEGRRDRQHQQGADPGRSPGNLVISEVRQSDEGRYVCVAENMAGFRESVPVHMAVYVKPFFVKEPEHLTVLANVDITFPCKVDGDPRPSVIWRKINGKLPIGRAELSDDRSLIVKNVTVADEGTYICEAENLVGSITSEVTLTVHSRPNFFNKTKRSKNWVERYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XB87</accession>
    <name>A0AAV4XB87_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Transcription elongation factor SPT5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SUPT5H</name>
        <name evidence="16" type="ORF">CEXT_748291</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017374">
        <property type="protein sequence ID" value="GIY91054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XB87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06081">
        <property type="entry name" value="KOW_Spt5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06082">
        <property type="entry name" value="KOW_Spt5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06083">
        <property type="entry name" value="KOW_Spt5_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06084">
        <property type="entry name" value="KOW_Spt5_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06085">
        <property type="entry name" value="KOW_Spt5_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06086">
        <property type="entry name" value="KOW_Spt5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09888">
        <property type="entry name" value="NGN_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000013">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000016">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000017">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.940:FF:000003">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="entry name" value="NusG, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041973">
        <property type="entry name" value="KOW_Spt5_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041975">
        <property type="entry name" value="KOW_Spt5_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041976">
        <property type="entry name" value="KOW_Spt5_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041977">
        <property type="entry name" value="KOW_Spt5_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041978">
        <property type="entry name" value="KOW_Spt5_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041980">
        <property type="entry name" value="KOW_Spt5_6_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057934">
        <property type="entry name" value="KOW_Spt5_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057936">
        <property type="entry name" value="KOWx_Spt5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039385">
        <property type="entry name" value="NGN_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039659">
        <property type="entry name" value="SPT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024945">
        <property type="entry name" value="Spt5_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022581">
        <property type="entry name" value="Spt5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017071">
        <property type="entry name" value="TF_Spt5_eukaryote"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125">
        <property type="entry name" value="SUPPRESSOR OF TY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125:SF7">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23042">
        <property type="entry name" value="KOW1_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23284">
        <property type="entry name" value="KOW2_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23291">
        <property type="entry name" value="KOW4_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23290">
        <property type="entry name" value="KOW5_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23288">
        <property type="entry name" value="KOW6_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23287">
        <property type="entry name" value="KOW7_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23037">
        <property type="entry name" value="KOWx_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11942">
        <property type="entry name" value="Spt5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036945">
        <property type="entry name" value="Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01104">
        <property type="entry name" value="CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="16" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusG-like N-terminal" evidence="13">
        <location>
            <begin position="223"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="14">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="14">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="14">
        <location>
            <begin position="518"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="14">
        <location>
            <begin position="640"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="14">
        <location>
            <begin position="762"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="Spt5 C-terminal" evidence="15">
        <location>
            <begin position="830"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="14">
        <location>
            <begin position="1060"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="24"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="714"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="839"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="62"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="726"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="914"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="934"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="958"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
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            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR036945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY91054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1112" mass="122101" checksum="9EB4CC1CFDC89E4C" modified="2024-11-27" version="1">MPQHRNGVPLIINVLDAELKAMSDTDDSNYSANASEESDIEPDDAKSDVGSEADSDAGSQVNDDEAEEVTEAEAAAEEQVEEEPEGEDLDEEDEEEEDEDDDDDEDDDDDDKRKRKKKKPRYGDFILDEAEVDDEVEEEEEWEEGAEDIIDRTRPTEENTSRDIDSHRRLQMMWTSQKEDEIEDYYRKKYAESSAAEKGYGDGGDHELPDEIAQQTLLPSVKDPNLWMVKCRIGEEKATVLLLMRKFIAYQYTEEPLQIKSVVAPEGVKGYIYIEAYKQTHVKQAINGVGNLRMGQYQQTMVAIKEMTDVLRVTKEKAQLKPKQWVRLKRGIYKDDLAQVDYINVASNTVQLKLIPRIDYTKKRGALRTNEQEKRKKGKKPPAKLFDVDAIRALGGEISTNGDLLVFEGNHYSRKGFLYKSFAKSALIVDGVKPTLSELEKFADESDTTKMTLEFSEGSGEDASHSFSPGDNVEVCEGELIHLRGRVIAVDGNKVTMLPAHDDLKDPLEFPAHELKKYFEIGDHVKVIAGTYEGDTGLIVRVEENVVLVFSDLTMHELKVLPQDLQLCTDMATGVDSLGQFQWGDLVLLDPQTVGVIVRLEKEYFHILNMHGNVIKVKHQSVSKRKDTRRAVSLDSESNQIQVRDVVKVIDGPHSGRQGEIKHLYRSFAFLHSRMMTENGGIFVCKTRHLILAGSGNGGNRPLSEINMRSPFHAASPRITSPSHPSGGGNKPAGGFIAGGGGAGGRGGGGGGFGRGRGRRDSELIGQTIKITHGPYKGHIGIVKDATEATARVELHSKCQTISVDRSRLAVVGGPSRGSLSSYSRTPIYGSQTPMYAAGSRTPMYGSHTPQYEAGSRTPHYGSQTPLHEGNRTPSHGGAWDPTNANTPARGSGDFEEYAYDESSPSPTAYNPATPGYPETPQGPYTPQTPGSALYNSDHTYSPYQQTPSPSAYPGGTPSPSAYAATPSPSAYVGTPSPSGYGYSPMTPGAPPTPEVGLDMSSIEWQTTDIEVIIKDSHGDDGLSGQTGIIRGISGGMCSVFLLKEDRVVNILGEHLEPVVPQRGDTVKVIMGEDREATGKLISIDSPDGVVRFDNTKEAKMLNLKFLCKMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC05</accession>
    <name>A0AAV4XC05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_276681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000173">
        <property type="protein sequence ID" value="GIY92635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12375" checksum="5BF80C2CE90E3D99" modified="2024-11-27" version="1">MISVSSVQTLYVDKLPSVRVLVLMKDRSQTGRKFRATVFRCFMAVQRKADSSHVEYFLTLSFSQEISIIHLRLHKNDPQVIAFTVDFTHAIKASAIKCELTDSAAVQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDL7</accession>
    <name>A0AAV4XDL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_86711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017629">
        <property type="protein sequence ID" value="GIY93132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15912" checksum="5C67E176CFCD3E25" modified="2024-11-27" version="1">MLTLSIGFEHQFNHESKNTFTLTTASNYTELYFNHYLLNPLNKILINPYLGCQSISFNTQRRKYQLIVQICIQSSRIKPNCSTAKPLNDVFQSFKTQAVLCRVRGIRTQAAAATCVLKPTTDCHLCMKISPNFMLVIGCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGU0</accession>
    <name>A0AAV4XGU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_349651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017777">
        <property type="protein sequence ID" value="GIY94362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14609" checksum="509BA226B1A3F5EF" modified="2024-11-27" version="1">MPLNPNFHVQFSNRHRNYSTFSVSKLNEFGRLMYLIRAHLHITLTGHYLVGPFMLMRGQILNRITCSGDNVCRHSETKDFSIPVKLNIYLASCEMNSEALLKEISKRICVFVANKACQKRTWSFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGY3</accession>
    <name>A0AAV4XGY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_579811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000258">
        <property type="protein sequence ID" value="GIY93329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="10984" checksum="AB297137B6860C8C" modified="2024-11-27" version="1">MTEIIIKEGTNSIFTPFLPMAFKIPQIPVDQAPSPIAATPFHQKTTLFLPPSTSSVFAAHQRMELLTSKTLGVNPGETSREPFLPRLVPRSTRSGHCPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH88</accession>
    <name>A0AAV4XH88_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_215611</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000341">
        <property type="protein sequence ID" value="GIY94029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000064">
        <property type="entry name" value="Early growth response protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF60">
        <property type="entry name" value="STRIPE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="381"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY94029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="473" mass="51981" checksum="E489F9C3264A5C24" modified="2024-11-27" version="1">MTSEISAVPDSNWLAPLDNLPNMEAMLSETFIHELRCDDLHNEIMMFSNDEDPFGARDIVLNELRRRLSKVRVTPIIKCPIQIDTISSTTVIPSKLENCLESLVETTTSLAEASSVSIQAQKCFNQPRKMFGLVEITANLAEANSVPGQPQKCSSQPRKMFGLMEITANLAEASSAPVQPENSSNQPRKMFGLLEIPNNIAEASSVPRPVLCQSSLKTIPTSPGKGFTWWKLPAVLQRPVLCQSCLRSAYQPAQKIPGEMETTSNLAETRSVPVEPQKCANQPKIIPGEMETTANLAESSSVLVEYQKCSNQPQKIPGEMETTANLAEASSVPVGAQKCSNQPSKKSHEVEITSNLAKSVLCESSVGGVPTRKEKALERLYSCPIDNCVSRFFRNCDLIRHLKRHTGQKPFKCRVCPKAFCRSDHLITHIRTHTGEKSPTCATRAEKDSKGAMRGVGTKTAPEAEVRDICQCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XII9</accession>
    <name>A0AAV4XII9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_760871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000456">
        <property type="protein sequence ID" value="GIY94957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XII9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="11065" checksum="E3F34A08CA5812A4" modified="2024-11-27" version="1">MFVLVTFPFGNISIIGNRRNNTNETCSCTEQSWCTGEYCILYRSTLSHNRPCLLKSGYSVYRTCPWILSEDPPRSNWVIFSKVHQVPRPGFSVRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJ80</accession>
    <name>A0AAV4XJ80_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ADAM10 endopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ADAM10</name>
        <name evidence="7" type="ORF">CEXT_543801</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endopeptidase of broad specificity.</text>
            <dbReference type="EC" id="3.4.24.81"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.81" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01000333">
        <property type="protein sequence ID" value="GIY93975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJ80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049038">
        <property type="entry name" value="ADAM10_Cys-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051489">
        <property type="entry name" value="ADAM_Metalloproteinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45702">
        <property type="entry name" value="ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45702:SF3">
        <property type="entry name" value="KUZBANIAN-LIKE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21299">
        <property type="entry name" value="ADAM10_Cys-rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13574">
        <property type="entry name" value="Reprolysin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="6">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="5">
        <location>
            <begin position="137"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY93975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="375" mass="41113" checksum="30C805E393946255" modified="2024-11-27" version="1">MFTYRDFEGGTLGLAWTGDLKNAGGVCEKNGHYRGSLKSLNTGIVTLLNYGKYVPPIVSHVTLAHEIGHNFGSPHDPEDDIVCTPGGDNGNYIMFARATSGDKRNNNKFSPCSVRSINAVLNTKARSLKGCFTEIQDSICGNGVVEKNEQCDCGWEEDCEESCCFPMRTNPPRDEPPFLAKVPAVLMIAVSKLERNAEECTGSICVAYGLESCQCRRGTNDPVTKSCELCCKLPADDYSCKSSFEWNSSPYDVPDLYAKPGTPCDNYNGYCDVFQKCREIIIFRLFAKENESPKSLTECGQTNKTIGVLRPCSNEPLVKARTQALAASSSIAMTHTSNNRKLQAILSGPVYHLFQISTDLCLCREMGGYDGNLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XP82</accession>
    <name>A0AAV4XP82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cysteine and histidine-rich domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">chordc1</name>
        <name evidence="7" type="ORF">CEXT_607961</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018054">
        <property type="protein sequence ID" value="GIY96489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XP82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="6">
        <location>
            <begin position="356"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="CHORD" evidence="6">
        <location>
            <begin position="497"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="5">
        <location>
            <begin position="567"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="417"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY96489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="673" mass="76437" checksum="C62F301CB032376E" modified="2024-11-27" version="1">MPRRPLTDAERLESKKRKQEACRKYAKSEKGKALNLKNKKKHLSIPEYREHINKLRRLAYQAKKRQLHVDKESNECQRPKLGVEMLNMTECQNRWPDSFPAFIPRTTKNKMAADFAESIYDIPENTSSFESVPLVNPDWLPESRQDVAKQGSASDDASNTNSPVIKLEVDIDDGSQNDALCPADGSGYGCIIPSSVCEVVTDTQQSHIQRCRTPTERRDIGTEFEFSDSSDEYPIEMFFKSMGATVKTFPPHLMVIAKLKVAKIIADLELQAMAEMGVDNTGFCGSNRSKWFTSDGLDHHQEIFPVPDSSRLVFIFWLHCEVKCFALFALFLLAKLGIIGTKSISIKMSENGKLLCYNRSCGQMFDPESNKEDSCLHHPGLPVFHDAYKIWSCCNKKTTDFTEFLNIKGCSRAYHSNVKPPEPEKPANKENNREVPSYPKPLQQKEALPRPDINEPLQRLSHIIGSSLKSMLEKMQKEITLEPIEVDSSIVQLNTPCQNKGCQVAYKGEQSNAETCLYHSGVPVFHEGMKYWSCCIKRTTDFNSFLEQVGCTTGKHKWHKEKNIENKINCRFDWHQTGSSVIISIYSKYSLPDLSYVESNAVKLLVHITFGKHKEVFEEEFVLFGIIDPSASSVTYLGSKVEIKLKKVEPICWTNLRLKKDILSLGSMSLEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XPR7</accession>
    <name>A0AAV4XPR7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_714801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000728">
        <property type="protein sequence ID" value="GIY97016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XPR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17439" checksum="1E278FA95D80D6B1" modified="2024-11-27" version="1">MEEWKSNSAAGIRLLFDFGGLRRVGGDAQYILKESSRVLEKGEGVKHSIGWNLNGNSLIVTSLQILRFAIGIAEKTVTLRPFNNFLFNVRGIKREKESSPSVDPVLIEKLTLMCLNYHIKRDERPEQIRRRKKPPCLMWGNNHPKVPTVARIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR27</accession>
    <name>A0AAV4XR27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_233081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000708">
        <property type="protein sequence ID" value="GIY96833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13021" checksum="6B4537213F0E9DBE" modified="2024-11-27" version="1">MFRGVEERKGVVRGKELQQIETSKHRRSCRLWGVREGKAPRFRLARCVFTLHVEWMSEATQLGGKEGCGEGRGREVSASARSRVHYRLGNSWIFMKTPDATGVEATLPLFQRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTH3</accession>
    <name>A0AAV4XTH3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CaMKII</name>
        <name evidence="2" type="ORF">CEXT_652831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000748">
        <property type="protein sequence ID" value="GIY97159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9943" checksum="DF9FB83716D69E65" modified="2024-11-27" version="1">MGFAGTPGYLSPEVLKKDPYGKPVDIWACVYPSPEWDTVTPEAKNLINSMLTVNPAKRITASEALKHPWICQRERVASTPFTDKRQLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVA2</accession>
    <name>A0AAV4XVA2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_301131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018303">
        <property type="protein sequence ID" value="GIY98518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="5">
        <location>
            <begin position="26"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY98518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="16630" checksum="41EBC7E3EDDA55E2" modified="2024-11-27" version="1">MHLFQRYFCLSSSQISQSITMSDILNPRPFLKSLLDKKVVVSLKWGNKYFGKLTQVDKYMNLALEDVAEIRNGKRSNTTMKTVLVRCNNILYIQECTKEIEEQECVKETEAQECVKEMEEQECVKEMEEQECNSGEGTHVTEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVF1</accession>
    <name>A0AAV4XVF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_29541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018387">
        <property type="protein sequence ID" value="GIY99145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="21655" checksum="8CE3C94BA2088972" modified="2024-11-27" version="1">MPLRTFQQGIKQVVRLIDANTCYILVGHRTRLQYSCWNIHPYRVLKEAVTSQILLGKEKEPALSYGTEAEEEASLLTSEGVRSRFQLKLSPLLERSFSGLSWARYLILPESYWILQKTPAQNPELIRRPPDFCSLFGPTPPVPLEEEGEGNVVKCKLHSCSGESTPGPKSGWYTNGDRLADGETVYPSATVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVQ4</accession>
    <name>A0AAV4XVQ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_398011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000842">
        <property type="protein sequence ID" value="GIY97848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVQ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9361" checksum="BD23445F333F4A5B" modified="2024-11-27" version="1">MDIPDQVGHRTRCDRWFWSVAFREGQGYRLDHLSKQVGPGSQDLSLEEPVGPGDSFEPGEPGVSLGPGGPGAINGGSGGFLFREGQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0L9</accession>
    <name>A0AAV4Y0L9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2</name>
        <name evidence="2" type="ORF">CEXT_543001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018605">
        <property type="protein sequence ID" value="GIZ00958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0L9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ00958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13332" checksum="B0F7557D073AAD3C" modified="2024-11-27" version="1">MTKENPFSVLNRPLESSFSNSSGTEVRCVADGVPNPNLSWRIKEGGNAPDVPGLRYTRPDGTLVFLPFMRNDYRQDVHDTVYQCLASNSIGSVISRGSRQRSFVECRILVTYWKTMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y0U8</accession>
    <name>A0AAV4Y0U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_508101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001083">
        <property type="protein sequence ID" value="GIY99783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y0U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="170" mass="18828" checksum="B23DEFCED02141D8" modified="2024-11-27" version="1">MKIFRYPTTPASLSFHCKQGGTQGGGGRRHSLENECRKQRACLQAMRVSVVPLSSVSHQAESNFKTILASSCPVPLRTPRSYDCVDPTGRKSSARCGGCTAYQTRWFTRISPFAAEDFRQGVHDAVYRCVASNIVGSIISREVHVKAENVIQIRNLYCVAWWLCGMVPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1B4</accession>
    <name>A0AAV4Y1B4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein tumorous imaginal discs, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">l(2)tid</name>
        <name evidence="10" type="ORF">CEXT_260751</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001216">
        <property type="protein sequence ID" value="GIZ00863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1B4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000005">
        <property type="entry name" value="Chaperone protein dnaJ 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051938">
        <property type="entry name" value="Apopto_cytoskel_mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145:SF3">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="84"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="220"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="6">
        <location>
            <begin position="220"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="431"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIZ00863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="464" mass="52592" checksum="F4CFB9C2FB017838" modified="2024-11-27" version="1">MKHNLRILREITLSPTCRLQNKPLLKTVTNFFHSHRTRTFSKIYSLNRFNFLTYGGNISRSNVSSFYFIVKQFHQSYNNYAKPDLYKLLGVSRNASQNEIKKAYYQLAKKYHPDTNKNDPTAAKKFQEVSSAYEILGDEKKRKEYDEWGTQAEFQNRREASANEFRFHSNIDPEELFRKIFGDLNFNRRMSDFEYADSHFGYGASEHVQVQLDFHEAAKGCQKHTVVNVVDTCTVCKGTCCVPGTKMVRCDHCNATGMETVSAGPIIMKTTCRMCHGTGMFNRYPCVECAGKGSTVQRKAVMVNVPPGIEDGQTVRVRVGNQEILVTFRVTESKYFRRDGSDIHSDAIISISQAILGGETKVQGLLADLILKIPPGTPSHKVFRFPGKGIKRPTGFGHGDHYVHTKIDIPQNLGKVQYDLIKAYAEMEKNTPGSIRGISSSKTKETEFSGKEEEKEKKGILEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y930</accession>
    <name>A0AAV4Y930_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_651151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018814">
        <property type="protein sequence ID" value="GIZ02451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y930"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9964" checksum="22B04060B66057B1" modified="2024-11-27" version="1">MKFNANKTKTRIRYKEVEEEEKRIFSKYRNNRATEKKKGKKCGPESHNIRDYGRRKPPLEVANYLLKEYVSSSPSAAFFQYFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAX1</accession>
    <name>A0AAV4YAX1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_164831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019118">
        <property type="protein sequence ID" value="GIZ04636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAX1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9260" checksum="5C206818F5D278CE" modified="2024-11-27" version="1">MQNVRYSVQVFSQKQNSSTGSKNTLMQIHSCRDRTISPAHSSLALEMKTQIQNLDHQIETYETWKQKFGEIPHHLEETAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M353</accession>
    <name>A0AAV4M353_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_82621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019331">
        <property type="protein sequence ID" value="GIX66668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M353"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11359" checksum="924B5AE4070DA00F" modified="2024-11-27" version="1">MQPHLYITNLSKNHDKFYRNEKAIFIKRGLRNKKKLQKVADSFKLQKYRLINLFAHSLRTLSDDIARHPQSMEGGLVLQELCSVRHISPVKIGMVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5J1</accession>
    <name>A0AAV4M5J1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_649961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001894">
        <property type="protein sequence ID" value="GIX67696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043517527" description="Secreted protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="15470" checksum="AE966660BAAE5305" modified="2024-11-27" version="1">MLFSGNSAFHPCPRERKIFYFLLLVAFPSCQPAWVCTREENVHDPFSIVFYFCKSGSPGLEKRGRRNTGLKIDTHVTCESANGGFPVCPTPFLIAWTDGLHQTKAYFPLFPEKEWYWICRLFVSSFVYHPLLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5N1</accession>
    <name>A0AAV4M5N1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_626971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001893">
        <property type="protein sequence ID" value="GIX67689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5N1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12166" checksum="9B7515E8F2341AB0" modified="2024-11-27" version="1">MLSDFSLQSVYILGLINFNFRLSFLPPPPVLDRYSPFGELDGIDHIADINVHDCEEIKRDSGQRESADYYWKKVSCGVVAAKKIKGFLHTLFNTAACSMLRVVQEMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M718</accession>
    <name>A0AAV4M718_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane protein 53-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tmem53-a</name>
        <name evidence="8" type="ORF">CEXT_498021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus outer membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMEM53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019330">
        <property type="protein sequence ID" value="GIX66644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M718"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF30">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX66644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="271" mass="31098" checksum="970C7DFE50A10474" modified="2024-11-27" version="1">MDDDFEYYITFPVIAEPVVSKEPVIILFGWAGCVDRYLAKYSEIYQKKGCTTIRYITSPNVVSPRVIDEKKIHNLAGNVINLLIDMKFDKHPIFFHVFSNGGATVYRYVSEMMRKKHPDDFKIKGCIFDSCPAKVRASGFVRATLAMTEGSLAKRYMIAFVALVRALILGAYSAMLSFLTGKINYYLLWNALVEEPNICPQLFLFSKADNVCCWDTIQEFAESRKKRGVDVKTVLFEESDHVKHLVKYRDEYLNNVYSFIDEYVGPTSPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8D2</accession>
    <name>A0AAV4M8D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_138001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019477">
        <property type="protein sequence ID" value="GIX68299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="9678" checksum="CB4F00F3B5F039C8" modified="2024-11-27" version="1">MALTLITPFCMIHNSSTENHSHYTVARGGCGNLSANPNEGNEFPNSSKGQQLRAGFNLHSLENGGQSGLVLVSVALISGYNNRSTNKKSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFJ1</accession>
    <name>A0AAV4MFJ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">U6 snRNA-associated Sm-like protein LSm8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">LSM8</name>
        <name evidence="15" type="ORF">CEXT_88411</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the precatalytic spliceosome (spliceosome B complex). Component of the U4/U6-U5 tri-snRNP complex, a building block of the precatalytic spliceosome (spliceosome B complex). The U4/U6-U5 tri-snRNP complex is composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8 form a heptameric, ring-shaped subcomplex (the LSM2-8 complex) that is part of the U4/U6-U5 tri-snRNP complex and the precatalytic spliceosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019688">
        <property type="protein sequence ID" value="GIX70595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000022">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 13" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 13" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="14">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00067760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX70595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10494" checksum="1ACCF8CB3A763952" modified="2024-11-27" version="1">MASTLDSYVNHTVSIITADGRNIVGTLKGFDQTINLILDESHERVYSSSQGIEQVVLGLYIVRGDNVAVVGEVDDELDKRLDLSNIKAEPLNPVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFJ9</accession>
    <name>A0AAV4MFJ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_36171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019689">
        <property type="protein sequence ID" value="GIX70653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15763" checksum="C797006BE7E13DE3" modified="2024-11-27" version="1">MRLQQMVLMEREEFPHLDLHPLRTILFGRMGRRSASLWYEDQTGVKDTLHTLLGTSQPVLKDAAFGCLVFPIPKRGFVRGGRGANATVTIPPRKGTWSIPLDSYAPRGLNMARRGGGVEKFRRPKNWKDQGATGMAFKSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHK0</accession>
    <name>A0AAV4MHK0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Double jelly roll-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_262692_1</name>
        <name evidence="2" type="ORF">CEXT_83261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019750">
        <property type="protein sequence ID" value="GIX71388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHK0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049512">
        <property type="entry name" value="DJR-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36159">
        <property type="entry name" value="PROTEIN CBG23766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36159:SF1">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21738">
        <property type="entry name" value="DJR-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Double jelly roll-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24461" checksum="12C61E8DC1562B50" modified="2024-11-27" version="1">MLYTDVTNKVYKVSIPNITLWLPHVRLNPEVSVKYLAFLESNEDLEIEWVAPILRESDSLDDNSGIIPVKILADDIVSILVIPQYVERENNVNQNNMVFDNLDLTSCSITINDIRYPKDGYRLSFKEGEINCSLPYLEFLKIFGNTRNTEAGCLITLDEYINLYPIMPFDASNHPPFINVKNLNIEFSWNLRNTPAKKYKFYFIINVKERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N206</accession>
    <name>A0AAV4N206_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_635851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020412">
        <property type="protein sequence ID" value="GIX78458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N206"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9350" checksum="289BEDA7D47FD7AB" modified="2024-11-27" version="1">MEDRKRKESCAEADLCMFLFSAAAAAHTFFHFLCDAGSEIGIVLPKPQKRKFSAPIPLALKSLIIFNGHQFARTVCYLILCITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N757</accession>
    <name>A0AAV4N757_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_621771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003055">
        <property type="protein sequence ID" value="GIX80692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N757"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20889" checksum="137E14AFAD6F1AE5" modified="2024-11-27" version="1">MQVKRSKRVSSSTNAFPLENDRNEDEKADAGTARSRCRRVQEGQCCRQCFRFFDHEVMPSMVMAVLVDGLVPVLSYDDGTERHVGFFLFTMPMSPVQFSPSVRWPKHLDLWARRTCTSDPTSSEIRRGICREIQKLTITLPLFCLFPNNRTEAKWRSSMAGVIGLEDFDNQNNSNLKSSKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9J9</accession>
    <name>A0AAV4N9J9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Solute carrier family 35 member E3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Slc35e3</name>
        <name evidence="7" type="ORF">CEXT_241171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020657">
        <property type="protein sequence ID" value="GIX81196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9J9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="16"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX81196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="305" mass="34518" checksum="86314DB7673B4A55" modified="2024-11-27" version="1">MCERRDVPLCLFGNIVLSVAIVLVNKIVYVRTQFPNVTLTFIHFVVTFCGIKLCESFNVFQVKRLPVLQVLPLAISFCGFVVFTNLSLGFNTVGTYQILKTLTMPTIMLIQTFMYNRNFCWKIKSTLVPISLGVILNSAYDIKFNALGTVFALIGVVVTSFYQVWVGEKQKEFQVNSMQLLYYQAPLSALLLVFCVPIVEPPWTPDGLFYRNWSITDLLLVLLSGVIAFSVNVSIYWIIGNTSAVTYNVVGQLKFCLTLIGGYLIFMEPILPIQFLGILMTMFGVSLYAYFKNQHQKTLPFIAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NBX5</accession>
    <name>A0AAV4NBX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_99251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020751">
        <property type="protein sequence ID" value="GIX82153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NBX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11153" checksum="826E151536DBFCE4" modified="2024-11-27" version="1">MYMKTANECPDSLLPALRGSSHSAPSEIPLLKPRPHSLPANEQPPSGAISKKLFSRRDRLLPMKTSGWILEPSQASAHLNIPGQRPRKISNQGEHNKINIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCV8</accession>
    <name>A0AAV4NCV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_471691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020757">
        <property type="protein sequence ID" value="GIX82204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10019" checksum="13958DA81D3790E9" modified="2024-11-27" version="1">MKSSGKTSHRPNKMALSNLQLNRPRGWDVLFEAAFRVAGDTDISLLKQRIGEKVVIHYDPIIHVSYLRKSFHPIIYPQENRPQFCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEI9</accession>
    <name>A0AAV4NEI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_97191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003263">
        <property type="protein sequence ID" value="GIX82725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10392" checksum="47B65520DE90EC4D" modified="2024-11-27" version="1">MKEGKPSIRHGKLKLLQNVLLLCQKVEVKKSANELHLNTKTFKSLSASASSGGSETTTVYTLNSDGEKDLCFRRRNIEYRSPKAGWTIPITPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NGX5</accession>
    <name>A0AAV4NGX5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_37491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003260">
        <property type="protein sequence ID" value="GIX82694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NGX5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9725" checksum="2D7826AEC56845DD" modified="2024-11-27" version="1">MPQTRNNRKRVYRKPHWRLSNSCHLGVTIIILNKSVYKNGSTIRTRVSCSRGVTGQRQHSCHAEKRSRDNFESFRSRGPLAGIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NH05</accession>
    <name>A0AAV4NH05_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Amiloride-sensitive sodium channel subunit beta-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">scnn1b-b</name>
        <name evidence="14" type="ORF">CEXT_226921</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020926">
        <property type="protein sequence ID" value="GIX84069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NH05"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIX84069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="16067" checksum="5771E821B8C941AC" modified="2024-11-27" version="1">MPRLMAYTVRVCPTHGRVWFPERKIARKGSRAHLRSRLQNQDDSDSDEDKTVWEYCRKVFGSSSVSGVNHIALAKTRRRRFFWAFIFTVSLVGFFYQLGAFMVQYREFQSIVQIDIQNAGSLMFPAVTLCNANRQVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NIE6</accession>
    <name>A0AAV4NIE6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_195471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020984">
        <property type="protein sequence ID" value="GIX84572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NIE6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14518" checksum="76029FB3404D710E" modified="2024-11-27" version="1">MPMEYYINSTELLECCAIKTPSLFKQERDLPCADVKGERSHAFDKSSGLFGRPLLHVVTKKNLLPLKLPATMPMEYYINSTELLECCAIKCLSLFKQDRDLPCADVKGEREVMPLTNLPASLEDLFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLJ5</accession>
    <name>A0AAV4NLJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_164691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003492">
        <property type="protein sequence ID" value="GIX85249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13156" checksum="C16E62B945D4E89B" modified="2024-11-27" version="1">MRSALDPPSARLNTSTFYVRKHLSKKDNGDALRSSVAWGKSLSFRELCIEAQGPDQAPSMQGPGVRHPAVEGEARAGHGQDQDTQAGKLHTHLAHNDAKHKAYRGVLGSYVIVLRVMETSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR89</accession>
    <name>A0AAV4NR89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_239611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003671">
        <property type="protein sequence ID" value="GIX87317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17720" checksum="23E5FF19D4A395B9" modified="2024-11-27" version="1">MTPRYLKRLANAINETLHSPWDIDFGSLMVKSPQCTVIFTPLPIGKADIIYPQILEPVQKFSNVMAKETLTFPTLEEWDGKVRRGGVYTKNAFKAGILLSLKAVIWERAKLLENTNVIFLKFLSLHRNLPTFMAKETTALTFPTFEEWDARSCGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRA3</accession>
    <name>A0AAV4NRA3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_9381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021114">
        <property type="protein sequence ID" value="GIX86114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8874" checksum="8AFD80BBCFF2FFFA" modified="2024-11-27" version="1">MRAFHKVSEPAEFGRRKKEIFLHYFYLIDLRQMAQKVDSIESSRRLMYWIQDSLNLIYKEMLVSVTTGIWKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRH2</accession>
    <name>A0AAV4NRH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_105431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003539">
        <property type="protein sequence ID" value="GIX85722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="11054" checksum="A18B9F34176C658B" modified="2024-11-27" version="1">MSYENISMEIKEFRVIIDHYLDIAEGVYNSSSLIHNKKKQKISKIDEHSFLFLMGIPEINSIPCLPLAGSCSNNASTWKRMFRNRLECPIFICRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRW2</accession>
    <name>A0AAV4NRW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_291051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021247">
        <property type="protein sequence ID" value="GIX87557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15449" checksum="5F96F9FC00844A52" modified="2024-11-27" version="1">MKFIFKLKEVLRNKRLYPEPESTRNKTSCFHFLIEKQEIPNAGRGGRKKERRKHFPWKSLPTNMAQPLVHAHTTLEHTRKENNRLEQTAERLLETGESMLYHPNPWPQGTRTCRHGDSKKVDLLMSYVGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NS39</accession>
    <name>A0AAV4NS39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003701">
        <property type="protein sequence ID" value="GIX87647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NS39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10396" checksum="9AD97C0FE309AEFB" modified="2024-11-27" version="1">MDSLLIRWDPSFKMYAGPLSRWGTSIPMSRPSWSRGLHHPRQTNKGLLMALPTDSHRVLPPKVTLQMGVLPLQGVKCKQTILKQTCFLEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSI9</accession>
    <name>A0AAV4NSI9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_226027_1</name>
        <name evidence="2" type="ORF">CEXT_267401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021164">
        <property type="protein sequence ID" value="GIX86720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052729">
        <property type="entry name" value="Acyl/Acetyltrans_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041496">
        <property type="entry name" value="YitH/HolE_GNAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237">
        <property type="entry name" value="SLL0310 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47237:SF1">
        <property type="entry name" value="SLL0310 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18014">
        <property type="entry name" value="Acetyltransf_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="324" mass="36633" checksum="31BAAA24E38016AC" modified="2024-11-27" version="1">MEIGLFIFAIRRLVTIKMPVRSLKLGLLIQNKCFARSLREADLPQLMALRRELKVHDVESTIKTFWEMDSNGVKVVESEKGEIMGACAFIRNQDLYFGGLYYVRPKFQGLGIGIEVWNACMDHVGPHNAALNAVPGKMELYRDKGGFPTVEDEFFCQKYFSAQPVNPHKLSNIIPKDVIIEPVANQHFPTLYEYDYSIMGYERRLAICLNCREKNSNTFVATQNGRIIGYGTIKTSCMGAARIGPLYADDPLVAEALVKQLIISLPNVNGFVMNTLSNNPFAENILQKLGVPLVENLTRMYRKNKMVVNTSKIYAFFDLNLAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1E8</accession>
    <name>A0AAV4P1E8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021499">
        <property type="protein sequence ID" value="GIX90375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1E8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8457" checksum="2F21027C025FDFFD" modified="2024-11-27" version="1">MPYLLAERKFLFAFCHSVSQGLSSLLSEILQTVYLPGVIVAEVRSRKEQALPSAEQSKQGKICGFVNLALQGLGKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P211</accession>
    <name>A0AAV4P211_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenazine biosynthesis-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PBLD</name>
        <name evidence="4" type="ORF">CEXT_222521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003907">
        <property type="protein sequence ID" value="GIX90035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P211"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF17">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX90035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="306" mass="34043" checksum="93913B821976C39F" modified="2024-11-27" version="1">MEGYNLEDSKVLSLYIADAFTKYPFSGNSAAVCLLPFDYEIGNDAKHKIASEMNLSETAFVKIIKQEDSFQTGKRFSLDWFTPLCQVPLCGHATLASAAVLFTVHENISEVLEFETVSGILKAKKLPKNQIEIDLPAYNSNKVNGKYDKIIKAVVKNLPVEDAVMSSSKKLLIRLCDTVTRKELEAIKVNDAELLSLDKDIMGVIVTLKGSGKDSLDEEGNAYDFISRYFAPWFGISEDPVTGSAHSVLAPFWSNILNKKSLYARQCSPRGGELHIELQENRVCMSGNAVVVFKGQIYIYKLYCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5Q0</accession>
    <name>A0AAV4P5Q0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nesprin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Syne1_1</name>
        <name evidence="7" type="ORF">CEXT_265631</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021703">
        <property type="protein sequence ID" value="GIX92557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5Q0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034993">
        <property type="term" value="C:meiotic nuclear membrane microtubule tethering complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052403">
        <property type="entry name" value="LINC-complex_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47535:SF7">
        <property type="entry name" value="CALMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47535">
        <property type="entry name" value="MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="445"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="604"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="779"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX92557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1015" mass="116895" checksum="BFEC38F962347883" modified="2024-11-27" version="1">MQKEVVEIENKSPDGAVDFEGKRGGNLGAPTEKWTKFNFKLEGFRSNVDNVIDRLKEILSRIISSEVRLKEIRSRKKHQPHLFTGISQTYPYTLPPPWHGPIELHSEIREQKQVLVNLETESQELATDQPDSANVKQIIGQLTNLKGRLHTLEETVITQRNIIAKNLDEIKNVKDILKSERDELKAAELKVEAGLPALASLKDARDKKQDSEVSLRYQTSINSAITVIKKINYLADVGTQTTKELSDASIQCEFIQLQDQWREIAQTIQGWIEQCRLSLPCGKESASSKEEVIKWLEITEETNSRRHLIHLGSSIAEQEQLLKTIDTFTHWEEDVKIQLHKFDDIFVDQIEAVLKNIELLRTENDSRRSDFNGIYEEVKKLSDSHDTSEIEEITAMYSKLSELYQNTEELLSRKQKFLQKRLDFESWYKDMHENIDLLKSKVEGKKYTSDELQTATDELSNLQKEYEKKVNEVENLDEMAEKVNQVIRDRSTTLPVSVGDRLAHIERLLKTVRDLLTLEQEGLSNLNKKWDEFNSKYEAFCELHKEMEDQQAAYSIVHQLGRSLIEEDSSSFTTIQGYLTATDKQWEQDVSADDEAILLNHENCKQLEAEISAYKDRFEKLDAKVAQTKQKHSKLDTSYVEKENSNLQKRYEKVKGTASKIANFLSSSVERRYQMALQDYQRWMLTNTEKAVEIESNLVQGENKKTKLEVTAANIIQVLPPERHPEVQSVVDQCGKSQKEKLILKKKNLDDLLSIIQEICAENPEARLKTQTSEVTSRYQALERTLQETLRRLENLLKVKKEYETSKVTLQNWLQEMDKQLESNFDVSGDKEALQSKLQSLKDLLSKKEQNTPILSSVTDAGELIYLSLSMEGRDQIRKEMRCLRDSWDEKWEKVSTTIKNIESALMAWGTFEESCKQVGVWLNELSGQMGSEVQLKPTLAEKKLQLQSFKAVAQGILAYQTVITKLKDKASTLPESAPKHNVESFQAQYDSLISSAKDRVQICDQHVVEHENMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PD87</accession>
    <name>A0AAV4PD87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_525881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004485">
        <property type="protein sequence ID" value="GIX95257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PD87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04503">
        <property type="entry name" value="SSDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11508" checksum="AC29FF636EA6CB6F" modified="2024-11-27" version="1">MYSWRLSTRRRPCRWESAPPPKVDGSSDRWLSALFANDALVPPNPTAPSPLGQIPPNDGMPGGPMAPAGFFPNSHMRPSPPQQPVSQPSPHPQPPPPSQSDASEPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDN3</accession>
    <name>A0AAV4PDN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_466471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004481">
        <property type="protein sequence ID" value="GIX95221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11332" checksum="2FDF4157CEE0EC85" modified="2024-11-27" version="1">MNPNKRYIYIDILHTSKEHKCHLSYCNQSLRNKNRAKKEEFRNKRVAHIPNEISLYNRRARAVLGVQLATSLLRGRTKTTYQSDHLGSCCTKMELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLW0</accession>
    <name>A0AAV4PLW0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Alpha-ketoglutarate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">OGDHL</name>
        <name evidence="15" type="ORF">CEXT_617411</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01004720">
        <property type="protein sequence ID" value="GIX96950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000007">
        <property type="entry name" value="2-oxoglutarate dehydrogenase e1 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11610:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, isoform X4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="14">
        <location>
            <begin position="426"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX96950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="834" mass="95350" checksum="D6263A15108894A3" modified="2024-11-27" version="1">MFINNKEQCTWIRKKFETPGIMNFTKEQKRLLMARLIRSTKFEDFLARKWPSEKRFGLEGCEVLIPSMKTVIDRASELGIESIVIGMPHRGRLNVLANVCRKPLEQIFAQFSGLEPADEGSGDVKYHLGMCHERLNRVTNKNIKLAVVANPSHLEAVNPIVQGKTRAEQFYAGDTQGKKVMSILLHGDAAFSGQGVVYETFHLSDLPDYSTHGTIHIVVNNQIGFTTDPRRSRSSPYCTDVARVVNAPIFHVNADDPEAVVHVSNVAAEYRAKFGKDVVVDLVCYRRRGHNEIDEPMFTQPLMYTKIRKILPVLELYKRHLVEEGMVTEKEIEEEEARYEAILQQAFSNAEKNIRMLYNTDWLDSPWKGFFGTKDPNKCEPTGVSEDTLLHIGEAFSTPPKGSFKIHPGINRILTSRKEMVKNRVVDWALAEAMAFGSLLKEDYHVRLSGQDVERGTFSHRHHVLHHQTIDKNTFRPLCHLWPKQAPYTVCNSSLSEYAVLGFELGFSMTNPMALVMWEAQFGDFMNTAQCIIDQFISCGQQKWVRQSGIVLLLPHGMEGMGPEHSSARPERFLQLCSQEFEVLPEIDEDFAVKQLHDCNMIVVNCTTPANYFHALRRQMLLPFRKPLIVFTPKSLLRHPDARSSFDVMTEGTTFERLIPDEGPAGQNPQSVERVVFCTGKVFYDLIKKRAESKRDSSVAIVRIEQLCPFPFDLVKQEVDKYPSAKLIWSQEEHKNQGYWRDIQTHFETVTNHERHICYTGRPKSASTATGSKEAHKKEQEKVLLQDEERLITEVSSIPPPQVRFCLIMVRADVEVIEILRLIQSNSMTRFALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q0I1</accession>
    <name>A0AAV4Q0I1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC-type xenobiotic transporter</fullName>
            <ecNumber evidence="3">7.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ABCB1</name>
        <name evidence="15" type="ORF">CEXT_264331</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + xenobioticSide 1 = ADP + phosphate + xenobioticSide 2.</text>
            <dbReference type="EC" id="7.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01005332">
        <property type="protein sequence ID" value="GIY01535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q0I1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008559">
        <property type="term" value="F:ABC-type xenobiotic transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097254">
        <property type="term" value="P:renal tubular secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017085">
        <property type="term" value="P:response to insecticide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000479">
        <property type="entry name" value="Multidrug resistance protein 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24222">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24222:SF76">
        <property type="entry name" value="MYCOBACTIN IMPORT ATP-BINDING_PERMEASE PROTEIN IRTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="27"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY01535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="259" mass="28296" checksum="E448D449ACA2C8B6" modified="2024-11-27" version="1">MSNTSNIPKIDPYSKDGIHPRDFSANIEFHNGNFSYPTRKTVEVLRNFSLLIREGQTVALCGPSGSGKSTIVNLIQRFYDPLKGNVTLGDYDLKTLNVHWLRSKIGVVSQEPVLFSGSIAKNIEFGNANVTFPDIVAAAKMANAHDFIIKLPQGYDTLVGERGAQLSGGQKQRIAIARALVRDPRILLLDEATSALDAESEAVVQEALDKAQEGRTTVVVAHRLSTIRTADVICAMENDEGANCSSEEAHLVMLKLFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q7P7</accession>
    <name>A0AAV4Q7P7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_168211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005800">
        <property type="protein sequence ID" value="GIY05080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q7P7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="13893" checksum="56A95C1662FCB7AE" modified="2024-11-27" version="1">MTKSLSGNTVFLLRTKGKEEITCFHPGEALPSGISGANGNLSTLEGFQLFCRNHSKSRWGYELDSCAQEMQDFAFVVVWRGSNVSSCKNVGVVCCVPDQNTVFSFIFQRTNNAGFAVKLMGKKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QER5</accession>
    <name>A0AAV4QER5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_721551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006004">
        <property type="protein sequence ID" value="GIY06831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QER5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="12744" checksum="A23D89F88268AC09" modified="2024-11-27" version="1">MKPHNHLCGIPIKNSVKDSKEPGNWKSSPTANSTTPIDTHLRVPQQPDNQPSSRSCSFKMLCNTATCGILRRPSSRRSLVSMKQETKAGQATRGHHRFLRPVLAALHVSLCCDGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QFV7</accession>
    <name>A0AAV4QFV7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_394151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006050">
        <property type="protein sequence ID" value="GIY07127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QFV7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY07127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="36660" checksum="29E3EA13E8C5D76D" modified="2024-11-27" version="1">MEIEFSESEQLRSSESGSVSQADAARAEMCRSGSLKTYFGEHSEPCTNNKTHLFLVLNFIWIPFVPAVLQKRFLHRKEREKEKSLSNDAHLGGERKRGNNYSVSFLRTERNNGGQPRKPVPIQTCRWREETILPALLLQEERRGHQKPNKAKTEQQRKIKGRMGGREEKNIHKKPVVCEEEETFQRYLYIAKGGQETESLISCFPVQWRHGKLEFSKSEQLRSSESDSFSLVDVAGAEMCRSLSNDANLGGERKRGNNYSASFIRRKEIMADTPKNLDLFRLADGEKKRFCPHCYCKRKEEDIRSQTKQKQSRRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QGG2</accession>
    <name>A0AAV4QGG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_605171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005959">
        <property type="protein sequence ID" value="GIY06438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QGG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21855" checksum="D554FDC405F5CA60" modified="2024-11-27" version="1">MDTEIPRGWIPWSKERRPTYRTACTQVHDWREVRQTDKGIEIYGAIGLLSSIKTHGKTRVLTIGFEEERCTNLPLHSKFILRFSEGRLSLETHAGVWCYTTISVRIKNVEKYQTAGSDGSPQSFYNSSNWIVHFTHFLCARASQSRAGRRKEAKKEKEKKKSYKIFCILRVLNFMYSMCIKLSVFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHB7</accession>
    <name>A0AAV4QHB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_610841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006296">
        <property type="protein sequence ID" value="GIY08820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11845" checksum="A437A688BBF7BB1E" modified="2024-11-27" version="1">MRCQFGDSGEMGPPAYNIWTSGSLQTPNILKNMTKPNDTTHNGSQNNIFTSCTAMLSTSYTTDSGSPSQKRKMLDSENEDFEERFSKNAKKETTTKGCCCQSKFSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJJ5</accession>
    <name>A0AAV4QJJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_417191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006220">
        <property type="protein sequence ID" value="GIY08246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12976" checksum="0E45787473796F69" modified="2024-11-27" version="1">MWLNYRLQFALRQPDSRICQETAFGLPFFSSFSIIPNHVSSVRRMRIINSQKAGSSFKKCLNKLPIRNTFDGFPGFCSYLKQEMLPFIFFSEGNGIVFAHDRVEYQRIVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYP3</accession>
    <name>A0AAV4QYP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_103481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007142">
        <property type="protein sequence ID" value="GIY14773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY14773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10183" checksum="3D7D8E2015DEE73A" modified="2024-11-27" version="1">MNLGRSSKAMDVIENNRKSQEAGKNGSSIKQGIQSSPFTRKHRARRRNRQSRNTGTEIREISQGLVYEFFHENKCSKNAERVLLPFGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2P2</accession>
    <name>A0AAV4R2P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_124201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007220">
        <property type="protein sequence ID" value="GIY15316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10326" checksum="03B1F57DEF6A9BC3" modified="2024-11-27" version="1">MQLAACTSPSILIPEFPFAKRLFELRAELNCFKPAGRRNLFRVFVPKGTTSVIQYGGSMDLASEAVISIFPSLFLPFRTDFLDSMEWNSKCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R6T1</accession>
    <name>A0AAV4R6T1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_721861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007358">
        <property type="protein sequence ID" value="GIY16329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R6T1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="17356" checksum="5187134700393A3C" modified="2024-11-27" version="1">MATRPLDPDGRRSRPFRLLQKKKTQLAASRPLTTSLRHAFDWNSETKSDAEYNVLSTTSNKDQRNKRSEQKKKKIEVILAYRHFIIGISSMAYRWQHRQEWSKQQQKENHFAQLPLVREFERRAFTTVPQLPALLRASAVGHQVGPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCK1</accession>
    <name>A0AAV4RCK1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_20961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007711">
        <property type="protein sequence ID" value="GIY19072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCK1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10865" checksum="43AE5EBFF86D5A85" modified="2024-11-27" version="1">MRGSSREFCVLLESCFPAAQDCFAEKKPSHALCRDERADMFDFWTVKEFLVQLSGYKNETARSKLQIVQGSFAEKKTSTLYVSDKMTDMFGQSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCL0</accession>
    <name>A0AAV4RCL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_62111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007574">
        <property type="protein sequence ID" value="GIY18056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCL0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24255" checksum="295C68DE31F14EBB" modified="2024-11-27" version="1">MHLQRNNSDDFRSIKGWRMNRLGHSQSQEDLIGMRGGVPGMGGEFASRPSGGISHQGYWRIKRPQILIFQRPAYHVLQPTPTYTQSETTTTFTPSRRGAQNESFGSSVEPGGPYWNAEGCPRDWKEMRVTSSRRYFSSGILEDQKASCSPKSSYSEACMSRFCNLLLLTRNRRTPFQEFASCWKATPSVYSVLFYFLNSMKCARAPCSWFNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJS8</accession>
    <name>A0AAV4RJS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_606411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007862">
        <property type="protein sequence ID" value="GIY20268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13303" checksum="95FD9C05BC2B0C70" modified="2024-11-27" version="1">MTVDPEPRLPPIMVRFNDGLKEHVAAISNQHKEDVRVKLAGEQLKIFPVNSDVHRAVTRYLTEKKLEFFVITPKNQRPLKAVLKGLPVSYSTAKIEEGLSELGLKLDQAINGQGTLCVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RK41</accession>
    <name>A0AAV4RK41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4E transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EIF4ENIF1</name>
        <name evidence="4" type="ORF">CEXT_477631</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007892">
        <property type="protein sequence ID" value="GIY20487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RK41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036464">
        <property type="term" value="C:cytoplasmic ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018862">
        <property type="entry name" value="eIF4E-T"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12269">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12269:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10477">
        <property type="entry name" value="EIF4E-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="516"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="618"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="87"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="522"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="566"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY20487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1172" mass="131454" checksum="1BF5DB3C67EBEFA6" modified="2024-11-27" version="1">MAMVRQLTEGEIVNGSTPEDDNQSSEQVKDSSRPPSRTSSAGSKRESPKLPTLQYTKEELIKYSKSPLSKAWPEKLDPAYNNASGKWDPERWFMNHRGDRLMPLEESRSKRERQDDGLVSHKRKSSDPKERIKEEKDDIVLSPQRRSFGTGCHVIPQSSLARRPGSPNDGRDPDSFREPSRRIGSGRILSRDRDQRDWDRDREYGYGGRDRRDRFDQDDPDKDLRRYSNRYNRSDRRSRGGRDRIDEVEPEWFSGGPTSQSETIELVGFEDSEGRKPGKKKRSKQNSRRSSLKSDEGEKNETVSDDKSSQKKSETKQVETSKKTIIEVKEIEETQDANKSNTGFDLEQLFKMDWIPGLIHNEAPPETVTKEIGCSRFSQWFSKESPVPEDHESRNNKSAKTVQELEADLKRIVLGDKPPEEKSAFDKLLQHMSDSKNSQTASLSIGPIDKSKVIQEKDLLQDMLATSQRLSSPVQKSFNMFEDKQAIFKIPSVTSTFSQQNQSSPNDAFAHLLQQKQREQHMQQLHQHQLQEQQLQNHHQNQQHNQNASMQGFTFDVLSKILSSSSQSSISPSSGLQSASGQSANRNDIQGINSLQYQRQHDLLSSILNQQQQQQQQQQQQQQQQQPNMSQRNVLQAIQQQRRCPSSKEIPMQQTLALPTLGISPRQSPLPVDTISSAIPNQGRIPSPLVFGQQPPAISHAPAPIHPAALVQAMAQNSASPNTLQVQNPVVLQRVPSPQELAVHTQSILQNALIKRKLEEQKENYRKRQEAQRSNSPVAVTKNGISVLPHKVPGLSPTIAFTPTSVMRKIQSEKTENKEQKITLQQNGTKFPGSIDVKVPDGSQNFQKFSSGGLSSLGISTGIDCNFASVNNMSSQNTSGLSQAPRAVHGQAMSQPRSIHGVMNSVTPSLSMPNQGRPIVKVGMNQPLNPNSDLSRSNKPNVSHKSFLSSNNQTHNVHHDESNLDVINKYTWPQLSRQQNVSGMPAQLQMAATYAALNRPTLNPHHPSLVRPVNIATAGNVSSSNINFSLLRNPVQNPIRAQNNNINQMNHLNQLALQMQRNSLDSRQLQALAQSQRIHPATLQHILMNSQNQVAAAQAQVVGGFAGNRDVKHQHLMPGQPATNRQSPVNLAKWFGNDVLKQKMPEMPPTTQQKALLVEEVERQQQSTAVHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRF5</accession>
    <name>A0AAV4RRF5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_435031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008271">
        <property type="protein sequence ID" value="GIY23406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRF5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="186" mass="21342" checksum="D45401867C52297D" modified="2024-11-27" version="1">MSPVQAVVDKSNFCRPLLKVPEYHFWDMGLIHIGVTYDWVDQQSQSWKYIHAGQLWVLFAIYSYSVCLLFFFFFLLVFIPDIFIGSPTGVCCASGLNHFGHMLPLPFAYGLYVSLFFFAFFPKKKEEEKGREGSSKKGKEEEEGARERLSVSSVPVSFCKQIMNSIRWCCAEGIRPAGRPLMDSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RU91</accession>
    <name>A0AAV4RU91_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_333521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008509">
        <property type="protein sequence ID" value="GIY25275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RU91"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="17729" checksum="8AC91687B612D76B" modified="2024-11-27" version="1">MGKTWGGVEKNFLLRMEMNNQPSNRLGWRDKNAATPHPPFPPSLTSKPPGLSFRKGKSTFSPGWPGKGGKTLGWIPRHISSSSVAGERGIWASIHRGSINWSCLQSFCFHSFGDAFCFLFGPWISNHGEMNGTERCPHCRVRGSVFCSGGMGVCCSSSCVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RY24</accession>
    <name>A0AAV4RY24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_492791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008563">
        <property type="protein sequence ID" value="GIY25599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RY24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="166" mass="18695" checksum="3890204875F9FECB" modified="2024-11-27" version="1">MHQDSVGRIYRETYYMLTIFLLGNILLTSLIPASILLSTSRGGFIYFLSSLLPVTRSKQSHIRRVSKPQCFTPPTPAPFFFCGSHLSKIIPRQTVSSARICRRHFHYARSADVIRLVLADPKAYCGTLSHDDALLCVCDPTLHGGRCIFGSYKGVIKLHIMGDRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZA7</accession>
    <name>A0AAV4RZA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_63391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008547">
        <property type="protein sequence ID" value="GIY25467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="352" mass="36883" checksum="75B229F7EAC558E9" modified="2024-11-27" version="1">MKLILAILVPSGDLPDLSQISKGDLANALGLGSGGLPGLPGISAGDLPDLSQISKGDLANVLGIPKAKLPDISQINLCGLPSLPGLGSGSLPGLPGRSKGDLANVLGIPAAELPDLSQISFGDLPNLSQISKGDLANVLGVPVGELPDISEIGGNLPDASLDANANGGGPSPNGAAASVNANGGGGGGEDLDVSTAKKLRDLLLKFNIDVSQIDMSQIDQLGHKYDASLLSKHHVREKLLHYIHIASPLFGTKTSKDSFNVIRIFFQSFWRPMEGYKKSIASGVYDSTINSKTDCENNENSNKSTTRVGVLLIFILLFCDSAQKHNSKLAQKLLQWFHWNVFDPPTVQADSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4M9</accession>
    <name>A0AAV4S4M9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_808461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008912">
        <property type="protein sequence ID" value="GIY28156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY28156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8780" checksum="0E48A222BA73FD83" modified="2024-11-27" version="1">MHLVAFCGTQNSILDNKAPGGVPFKDSKESAVELNENALGGFFVEHRTPFSTTKLREGIFIGFYLSVWIIEKSQVFKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SGK9</accession>
    <name>A0AAV4SGK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_426981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009533">
        <property type="protein sequence ID" value="GIY32692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SGK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13352" checksum="83A7A4402637BC4B" modified="2024-11-27" version="1">MTLDWRHRIGENMEWVSEDESYTGGGGLAHFFHKGIMLFILLKSIGNNHGKQCTPPSRDYSAQGANRWPSPGTLDNRKSTLRIHIGEINEMPLFSVPPSGSRRDFGFLNCFGPFGVEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SI11</accession>
    <name>A0AAV4SI11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polycomb complex protein BMI-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BMI1</name>
        <name evidence="7" type="ORF">CEXT_124341</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009720">
        <property type="protein sequence ID" value="GIY34073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SI11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035102">
        <property type="term" value="C:PRC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990841">
        <property type="term" value="F:promoter-specific chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000033">
        <property type="entry name" value="Polycomb group RING finger protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10825">
        <property type="entry name" value="RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10825:SF72">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY34073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="351" mass="39700" checksum="9F0DDDCDD6736BED" modified="2024-11-27" version="1">MQTSGNIQLKDLNKLLTCVLCKGYYIDATTIIECLHSFCRTCIVRYLQSNKFCPTCEVQVHKTRPLVNIRKYNFLSDYNSQKQNEGEMYSINDLDQTLQDIVYKVVPNLFKNEMKRRRDFYRQNDPIVERSIPSSSEKRGDVWGCDRLIFTPEDMISVSLEYFPLKMHASDSSSNLFSIESLHGNTNNGKKDKSRVRSDRRYFRCPGASKVHHLKAVAGKVWAFKFKEKTFFKIGEVTNVDITKEGAKTASENTVTSESLVASVMPTTSRCSIFPDASPAPVAAAPSSRHPSPPPSPQTAQEPNYFQVATQNVANMPREQHAGVPAMKLKSALKNLHLTSIVQMHLCMEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SPA7</accession>
    <name>A0AAV4SPA7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_524961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009753">
        <property type="protein sequence ID" value="GIY34310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SPA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10483" checksum="7155E26DC60B1AC2" modified="2024-11-27" version="1">MVVLGVIDNLMQFTIFALSLLRCIRDILYHAKRSKAIYSGRTSKHKSYRKCDTVQPGSATMSAKHCYSIFRFYLFSQFQGTRTQSNLIHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SPZ2</accession>
    <name>A0AAV4SPZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_603161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009783">
        <property type="protein sequence ID" value="GIY34550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SPZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8720" checksum="86480AA817D54B1D" modified="2024-11-27" version="1">MSPSRICLRQDVNKNELTLTSPVTIDGHVKSQIPVTEEHRLLCVPSNISQVPRMLKGDCPKPDDENMPTLVSFVGHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSZ8</accession>
    <name>A0AAV4SSZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_793511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010048">
        <property type="protein sequence ID" value="GIY36436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="19936" checksum="83943B22E4042D05" modified="2024-11-27" version="1">MFEAVNENGLWRKRHNFELYGLLNEADTKVFLKIGCMSDWSTSCLKFSFFISVPLLLKKKKEKKKKIFHPTLCFHQQIEPERERHCDAWGTNEVCRYIHRKAAKKKKKKPHQPGLGHKKLETKDLPDQDSKKVPFVSPVSAGSLKILCAGSPFLRVHYQIKGASSANVYLQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ST50</accession>
    <name>A0AAV4ST50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_336961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010134">
        <property type="protein sequence ID" value="GIY37189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ST50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11697" checksum="32A18A2C680D102A" modified="2024-11-27" version="1">MTKGLYPHWHSVTRAPFANPYFGRHIERGCLRSPQIFNRSLRIKPGNGFKDASRTFNRFSVLKRDKHSRPCKINGRTGRCFQGCHLMGFDLSHPSKREAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVJ4</accession>
    <name>A0AAV4SVJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_44331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010052">
        <property type="protein sequence ID" value="GIY36467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY36467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="13599" checksum="B99096980060A69F" modified="2024-11-27" version="1">MGSYFGNVILTSDSPLSSRAHSNSLDLKPLNLYSVTLANSCRLRAYYESNKTKSFRSDKAQVASCLLLPSLNSGVRLLPTTHGGAGHNFATQKRVVFSKRAPIPWVEGSHERDGGMVENPVAHIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T376</accession>
    <name>A0AAV4T376_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_493771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010532">
        <property type="protein sequence ID" value="GIY39936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T376"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY39936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="17770" checksum="CB867763E5164E13" modified="2024-11-27" version="1">MIASNSNQMKCKRVCILVYKSIRVCQQKDSRVSEIYRRVLRSIRVIILMNVAGNSSQLMFLINLCLMQIRRRRPTREVGYRFFPNFEWKVNPKENKGKSRQRNGFQTERKQQKGKVGTKVKRKRKKKKKSNFFFFSLLASFHIRKCHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCT8</accession>
    <name>A0AAV4TCT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Urease subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ureC</name>
        <name evidence="3" type="ORF">CEXT_719191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011070">
        <property type="protein sequence ID" value="GIY43999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009039">
        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050112">
        <property type="entry name" value="Urease_alpha_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43440">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43440:SF1">
        <property type="entry name" value="UREASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urease" evidence="2">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY43999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17142" checksum="6E9046CE7988F94D" modified="2024-11-27" version="1" fragment="single">FMIESTDGFPMNFGFTGKGNTSDMGKLSQALVEQIEAGAIGLKIHEDWGSTPAAIDCALEVAEALDIQILIHTDTLNESSCVEQTIEAFHGRTIHTYHTEGAGGGHAPDIIRVCSEPNCIPSSTNPTRPYTRNTVDEHLDMLLVCHHLDKNLKEDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMH7</accession>
    <name>A0AAV4TMH7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_409621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011344">
        <property type="protein sequence ID" value="GIY45927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMH7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="284" mass="32183" checksum="420B313920EB697E" modified="2024-11-27" version="1">METAEDERWRRMERAETMDYSVRESAQGASNPELMDTTCAAIQSERLASPTFPEKQSNLSDEEHCAHITTVIKKKDTAQNLYDAYAAALTGYSPDDDDLKELKIRHDDLQLAMREVSKLELCPLSSCKKHKIINFNSQIKRNAAHLNNHEHDNDGFTMPSKKLIAKVNCAKNPQHLVETKNSFEKVLIVDEQEEQDSDSTPIVKKMPPIMVKPTENLKTMLAKFDKFFETKATNRRRPQPIACGNGVWTVPLQSSAYVPKPQLPQAHPISHSFSRQAPHLMSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS72</accession>
    <name>A0AAV4TS72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_611961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011704">
        <property type="protein sequence ID" value="GIY48336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="20431" checksum="10A9051F158D9513" modified="2024-11-27" version="1">MKKSSDDEKTRNGNFHLKSKIHRGGSYKKKSINKTPIPGIIRKRGRPRLSESIPKSAKVSTFSENKSQVAFLQNTVCYIVAPKLSKCRECRLNNKNKKMQHVYCRFMEYRKLCFNKNGVIYNAGFSNPSDATDEHKNSWLPQPDNPPGNLNFKISKKKLLRLVGDQFCDLMVQERSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U055</accession>
    <name>A0AAV4U055_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_684711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012074">
        <property type="protein sequence ID" value="GIY51141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U055"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="301"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY51141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="353" mass="39969" checksum="D60F409BA0A0F2C9" modified="2024-11-27" version="1">MLGNVKEICDKYMDNYIEYKKKKYIDEEHTDKKLVHFPYLSDIEIYFKQGLPDIGTLLCPINIDSCLQMGVSHQEEVTTSESETSCLPNDIFSNIKTLPFEFIIDKFLFSDGLFDLKYFLKENNHSSVNVVKGQSITQSGKQLVNTSKPAVLNICTYDKISAKNKEATYIGNSAVQAQTNKKPAVNTANSDVNGQATYKRSINIEKSNVNDQTDIKQTVNKATCDVQKALKKTSSFDVRAYLSLPQPNLNFKISKKSATSNAKTSPFENKISRSPSNQLNPEQVGFGIKEKEKDNTCKERCNVYVGNIPLGYTEDDLRQRFEQFGKIKNIHLKPRKNYGFVIYSSQKRSSIGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U095</accession>
    <name>A0AAV4U095_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mortality factor 4-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Morf4l1</name>
        <name evidence="2" type="ORF">CEXT_310611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012078">
        <property type="protein sequence ID" value="GIY51175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U095"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18983">
        <property type="entry name" value="CBD_MSL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000024">
        <property type="entry name" value="Mortality factor 4-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008676">
        <property type="entry name" value="MRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053820">
        <property type="entry name" value="MSL3_chromo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880:SF48">
        <property type="entry name" value="MORTALITY FACTOR 4 LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880">
        <property type="entry name" value="MORTALITY FACTOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22732">
        <property type="entry name" value="MSL3_chromo-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MSL3 chromodomain-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10649" checksum="F83842B2BA6300E3" modified="2024-11-27" version="1">MHPPDFKLENSEKVLCFHGPLLYEAKCLRSQVKEKYVKYFIHYSGWNKNWDEWVPECRVLKYNESNLEKQKELYETHKTAKNRRLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U0D3</accession>
    <name>A0AAV4U0D3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Suppressor of white apricot N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CLASRP</name>
        <name evidence="5" type="ORF">CEXT_261121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012085">
        <property type="protein sequence ID" value="GIY51211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U0D3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040397">
        <property type="entry name" value="SWAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019147">
        <property type="entry name" value="SWAP_N_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161:SF4">
        <property type="entry name" value="CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161">
        <property type="entry name" value="SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09750">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01141">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Suppressor of white apricot N-terminal" evidence="4">
        <location>
            <begin position="97"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="210"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="618"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="413"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="638"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="658"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="682"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="706"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="765"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="780"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="796"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY51211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="824" mass="94858" checksum="B634EE2119EF75F9" modified="2024-11-27" version="1">MEDQTSKLDGNIWMELLAPSSVQFLNQYDHTIYLLSRLFEGGAIAHWLTLCSNLFDNLYFVELLGCEAAGTVLNNRQRCGMKRVNKKKRFVKQDPAQFLQVHGRPAKIHLDPAVAIVADSAATMMPWQGQADNLIDRFDVRAHLDIIPEYDPSSLKKKMKSQNQKIVNRVMKVSEEKFLNQIFLEERFGICNKPEEEKKKPSDKKAAIGYVYEDSTDSPPHLNILKDGEGDEDENDEEKEEDLSDIDLDVTVDVKMLTPAQCAEMNAHSHKYGMVDEDFITYLHHDKAEAEKLKAAREIEEEKAMYSGRKSRRERRALRKKKLAGRKITSPPSYAARDSPTYTPMRHSTSKSRSDGEQLGKSRSLSTNSKTEKNSKTKDNSDSVIGPQLPSKNGDDEKSTRMSRRSSYSDKRKHDKHHRGRARRRSRHSSRSSSGRSVTPKKSSSCDKKKSRRTSRSRSRSISVSKSRSRSRSCHQSHHNIEKPRSQSRSRSKSVSNVNDKKSDSPQLPPPPVKSYYRHSLSRSSSELSEESEEDNSPNQSPPLSNLSSSSRLQPLMGKAAPATKVNKIDSQERLKRKMQIALRKQYKADKLAQMEKTEKQLQEKTAEELREMAIKLRQREREKRHKLRGYGNDSDSDSTWTKNPDSNIQIPDVKRNSPTSSRSNSSYSSPEHSPPPVASSNKHRSRSKTPPRSSRRSPVDERRRSPYRRRSPMDRRRRSPYRRRSPARYSPRRSPHRSYRRSPTHSSRNQSCSHKYSPRRSPRRYSPTKSSRRYSPSKNDSRRNDSRRYEDNTSRHHRQGNHSPSRKSRSPSKSYGTKPLVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7L5</accession>
    <name>A0AAV4U7L5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_626271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012408">
        <property type="protein sequence ID" value="GIY53798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7L5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8248" checksum="91C184B6ABB1A2AA" modified="2024-11-27" version="1">MKGEDKDTGILAKLKAEPLALFLGLVLPLTLIFAAVLAIHLQLLHEWKHGSSPHLPQLLQATMVITDREAKTQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHS0</accession>
    <name>A0AAV4UHS0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1</fullName>
            <ecNumber evidence="1">2.1.1.57</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cap1 2'O-ribose methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cmtr1</name>
        <name evidence="5" type="ORF">CEXT_360761</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67020"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="Rhea" id="RHEA-COMP:17168"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167609"/>
            <dbReference type="EC" id="2.1.1.57"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.57" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01012857">
        <property type="protein sequence ID" value="GIY57075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHS0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004483">
        <property type="term" value="F:methyltransferase cap1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12760:FF:000004">
        <property type="entry name" value="FtsJ-like methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050851">
        <property type="entry name" value="mRNA_Cap_2O-Ribose_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025816">
        <property type="entry name" value="RrmJ-type_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16121:SF0">
        <property type="entry name" value="CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16121">
        <property type="entry name" value="CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51613">
        <property type="entry name" value="SAM_MT_RRMJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="G-patch" evidence="3">
        <location>
            <begin position="143"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="RrmJ-type SAM-dependent 2'-O-MTase" evidence="4">
        <location>
            <begin position="294"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY57075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="626" mass="71844" checksum="BAB520EBD133AC2A" modified="2024-11-27" version="1">MNKFKSLSDSSTSESEDDYGKRKTNATYESWGGSKERKMNFFLARSTDEEENQTELFIKMANSGANFKSPKKYSERSFSTDDTEDEITEPTSKKFKGGFKSPAKYIERELLTDQTDSDSEEKPSFSMKPAMTNMPSMDVLNGSYGVGMKLMEKMGYKTGKGLGKNEQGRVNIVEASKQRGRRGLGLTITGLEPSDTAWDASQEEIKVEETVSWMPDLDIKHLKLFQLREWMLEGKVFIHFSVKKETISDETEFCDPEILKKVIDNKSVFDNLEPEEMRKARTKSNPFETIRGGIFLNRAAMKMANIDSRFDFMFTDPKDIYGQSAVDKNELLYFADVCAGPGGFSEYVLWRKKWECKGFGFTLKNQNDFKLEDFFAGPPETFEPYYGVDGDGNIYSPRNLRSFQEFVLSNTENKGVHFMMADGGFSVEGRENEQEILSKQLYLCQFLCSLLILRPGGHFVCKLFDLFTPFSVGLIYLMCMAFEKICIFKPNTSRPANSERYIICKWLKDDSKDVADYMFEINEKLTKYLTTTSEKDIIEVVPLNILKENEDFYQYIVTSNDILGANQIVHLDKIRVFAKNVELHEERQSDLRKECLALWKVPDQARAAPPRCDPDGVYKTLMRHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMN3</accession>
    <name>A0AAV4UMN3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-tocopherol transfer protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TTPAL_5</name>
        <name evidence="3" type="ORF">CEXT_23032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013139">
        <property type="protein sequence ID" value="GIY58981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="156"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY58981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="343" mass="40027" checksum="1EC810FF2B69AC55" modified="2024-11-27" version="1">MNSSRGTSTFLKAIVIDVTLFSRQKDELQQVFLLRNWKFSREKKILQSCTSLVEIKMSMMNGEETYPLLMNFLPDAAVRKAEVELHETPENRLKGLKEIKKMLMMDKSTSNIDFEDDYLIQFLRHAKYNATRAFQRLRTMTIFKKKNSNLLIPLPDESFLTKSSPNFMLYLPKRCPDGCAIVLCRLGMLSPDEVSMTDIKRLFFISFTQTLRDPMTQINGVKIIHDFTNVSLRYLRHLTPSNLYLLKHASMDCVPARYKAVHIVNESIVMRAAWMIIHRFMTDKIIKRVIFHSDTEGLFDYFPRSILPPEYGGHLDDTSTDDWSRRTNKYQEQDTAGGLRSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V060</accession>
    <name>A0AAV4V060_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Voltage-dependent calcium channel type A subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CAC_4</name>
        <name evidence="1" type="ORF">CEXT_185751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013756">
        <property type="protein sequence ID" value="GIY63536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V060"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="434" mass="49286" checksum="5F96F27D6BCB5703" modified="2024-11-27" version="1">MSSSALDFTSDLFDPVKALSSNKVSLPFPKAKTYNNIAEYFSRKCLKQPRVPTTTKMKVEPRERNYEWYYDTLQLSQSQRARIRRFKKIKRRKGKKPVSIVTIPCEPLRSNRITKCQSDFKDYCRRKYPYLNNISASQDMSWSYVQQMAQTDSVLGENQLESVPASFIKSEPFDSVPTSIIKTEPIDSVSTSIIKTEPDSMSTPVIKMEPFNSVSTSIIKTELSDASFTSGTKAEPVSETFSGLEILKPGQMELCTLSPMENADNKIHFEKACSLENQCKSSTMTKDFEDQPVVSYSKEQINKNSKQSATFYKRKVSNKVSISSVTDKTESSNYTVVKDSSVRELHCKTRKRKKKTIDSLNTCKASSMSTVSMENKLLTSLPNEEKEINKHSTKPCKIKIKDKQLIKKKCHPDDLTLLPVSSMVPNDEFKLTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8Q9</accession>
    <name>A0AAV4V8Q9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Complement C3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">C3</name>
        <name evidence="5" type="ORF">CEXT_690731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014067">
        <property type="protein sequence ID" value="GIY66063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02896">
        <property type="entry name" value="complement_C3_C4_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.690">
        <property type="entry name" value="Alpha-macroglobulin, receptor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.91.20">
        <property type="entry name" value="Anaphylotoxins (complement system)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009048">
        <property type="entry name" value="A-macroglobulin_rcpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036595">
        <property type="entry name" value="A-macroglobulin_rcpt-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047565">
        <property type="entry name" value="Alpha-macroglob_thiol-ester_cl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000020">
        <property type="entry name" value="Anaphylatoxin/fibulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018081">
        <property type="entry name" value="Anaphylatoxin_comp_syst"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041425">
        <property type="entry name" value="C3/4/5_MG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019742">
        <property type="entry name" value="MacrogloblnA2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041555">
        <property type="entry name" value="MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF166">
        <property type="entry name" value="NTR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07677">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01821">
        <property type="entry name" value="ANATO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17790">
        <property type="entry name" value="MG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17791">
        <property type="entry name" value="MG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01361">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01419">
        <property type="entry name" value="Thiol-ester_cl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49410">
        <property type="entry name" value="Alpha-macroglobulin receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47686">
        <property type="entry name" value="Anaphylotoxins (complement system)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00477">
        <property type="entry name" value="ALPHA_2_MACROGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01178">
        <property type="entry name" value="ANAPHYLATOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Anaphylatoxin-like" evidence="4">
        <location>
            <begin position="700"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY66063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1562" mass="174045" checksum="1458A93A9C336EFF" modified="2024-11-27" version="1">MLSEKRSPKRTSFVTHCLLSIAMDTTVRCIGLLCFALFLSTASAQFFHVIAPNTFRLDSDETIAIAVEGKPSAMVNVVIQDHPGKIKKISETRLEVHAEQPSIFKVRLNPESFPPSFLTGNTEKFVLLTVSSDNFLKEIQIPVSNQAGYLFIQTDKPIYTPKENAHFRIIPLNENELPSDKPFKLQIKNPKNIIVEETLFNKKFQGFGKTFVSHTFKFPNFPVLGEWSATVKYGHEFEQNTTVYFELQKYVLPTFTVELKAPEVILETDQNIILTVKAKYVYGENVKGLVTYRLGVKGETPNVTFFAVVGPKKLKDGTHRQVVETKEFAHHRDIGWFPGIEGSHLVVEAAVVDDASGNKEVALDATGRFSKSPFTISFKRCLEDFKPGLVSIFEADINYIDGRPASGITTTIKALADGEPLEVKEPTHVSDEEGKVSFQFHPTMRHNTISVTLETSDARYVGNQAVGHFVQHRFKSDNNAFLALERSSTHQLKIGDNFQKILHIEPPAMRNIYYAVVSKGKIVSLNKLPEGDYKALKVSFRITHDMVPSFRLVTWAHYKDELVADSLQIDIEDSCNPGAKVTIEPQFELKEPGRAGVIHIKGTKDTMVGLLGVDEAVYALSKKDLLTKSKVFKTMAKHDLGCGPGGGLTTDDVFAKAGVLVATTKYSPKPGASSCIAVKRRKRAVANEILTQYTGLDKQCCALGLSHDQHNRNCEERTNVVTRYLQGNHENCSRAFLECCLYGKENGFTDMKLMRSGFNLARSGGVGGEDVQFISEEDKDFFEKQVTVRSDFRETWFFVDIPVGHYKHLLRATTDHEGQRILFFSYPDNKEEFAVSLPHSITTWVIQAVSVSPYHGICVAEPQKIVSFKKIFVQLNLPYSVVRNEQVEIQATVFNYGATRLGALVYMYGVKDLCTGANEGEKSESKRLYVDKQSAATVTFPVIPLKEGSFDVKVAALTSDGSDVILRKLNVVPEGAPVEVNIPIRLDPTNQQRREKRQITTPEYSDSIDPVQKLQITAINLAVPEEFVPGTESCTITALGDQFGPTVETAINNPDKLLEIPRGCGEQNMMFLAPTLYTMRYLKIKGKITPEIEEKGFSFIRLGYGNQLAFRKDDGSYAAYIHKPTSTWLTAFVAKVFCQANEIVYINEQVMCSAVKWLVDNQQPDGSFIEKSPVYHVDMMGQTPLTAFTLISLEECKCNIESLHLSRKRALAYLEDHLGDVNEPLAVAIMAYALSLSDSVLRQAAYDKMISIAKHNPDTNTMYWGAGDTAQDIETTSYALLTLLLNSDMERSNSVVNWLNSQRLQSGSFKSTQDTVVGLQALSEYAIRAQAPSMNLVANISSNNDRNFMQVLNFNEDNAHILKNIKVNKVGGMLFVNTAGHGIGSLSVKLRYNVVNPPEKICKFDVSVNVTEAKKDRSAAPKQEVGKVSSDLLPEDLIRGMENVLQEEDPVLDIDPRNRVKQRASLVANPLIPKRTKRQAGKDNSKVILKVSICARYLGNGTAGMSIIDVGIFSGFEASPEDLEELQNNPEHLIEQYETSSKGIVFYLKTVPKKRSTVSIFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VH01</accession>
    <name>A0AAV4VH01_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_572521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014435">
        <property type="protein sequence ID" value="GIY68760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VH01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY68760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14180" checksum="C295B87010D3A743" modified="2024-11-27" version="1">MSHSLNSQVEVQVLTQQKRTWRSRILPNTYVVPQELNRARNFPPFFSSFLSPTAFRAFDREINLFQKNLSSATLAAVPCKAERKRLLCGTPKNLLLAKERSHASFEQKGDGEGAGIRMDDKNIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VMH4</accession>
    <name>A0AAV4VMH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_573231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014837">
        <property type="protein sequence ID" value="GIY71646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VMH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="12148" checksum="EB7A0A4CBA611B85" modified="2024-11-27" version="1">MLEESNKTFEEERSLVRKENNEKLSELKKQLAKKVEEEENSGEINLVEIRKVNSQKLIEEEQKFKHELDSLKDNLKSEMEQMEQKNIEEINEKKKQLDEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VY26</accession>
    <name>A0AAV4VY26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_190771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015177">
        <property type="protein sequence ID" value="GIY74160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VY26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="12868" checksum="15250A1A4B4E15D1" modified="2024-11-27" version="1">MAAKGYSVGGQKHGLARGVPFLVPRDAVLRGGHGAGDHGRGAVRRLLPHLLPGGGEPPDAAPVPAPDEHLPPEGQAGSGRPEGRHEPKVQVGGHVATHAAQLSHIPGLHKRARDHGGDLRGSPGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZY0</accession>
    <name>A0AAV4VZY0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_293401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015379">
        <property type="protein sequence ID" value="GIY75713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZY0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY75713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10403" checksum="7104079BC81ADBBB" modified="2024-11-27" version="1">MLPCKIRKTSIHTAKLLMRSKHISKNFLIRLTEETGSRVFLINLDGRQWLYSVYEQDMIAYRLTGYDRSILTVLAFLQRLRAHCVTQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7F3</accession>
    <name>A0AAV4W7F3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_177841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015804">
        <property type="protein sequence ID" value="GIY78820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7F3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="58" mass="6585" checksum="A335F04EBFD565E4" modified="2024-11-27" version="1" fragment="single">FSQNPVALIPVLKFVYSLKRPPTKLYNKVMAASLTLLLYLITRDRHLNESEDPGDPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W992</accession>
    <name>A0AAV4W992_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_143770_1</name>
        <name evidence="4" type="ORF">CEXT_392251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015841">
        <property type="protein sequence ID" value="GIY79061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W992"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052129">
        <property type="entry name" value="Spermadhesin-Link_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46908:SF8">
        <property type="entry name" value="C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46908">
        <property type="entry name" value="CUBILIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="3">
        <location>
            <begin position="24"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY79061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="255" mass="28709" checksum="DA94280E08F5AE0C" modified="2024-11-27" version="1">MFTTSASVMEFVPPPSSTPLVKACGGIQKGNSGVIYSPGYPTHFPKDVECVWLIRAKPKQRIYIRILDLQLYGSIANCNDVELSIYDGYSSFIYNPQVMKKYCGDLKYYKNIEEQTIISKRNRLLIRFKTRVSSSKRKHVEVTGFKLLWSAVTLEHESTCTQFLCKSSKYCSPDNVSACESAPRFCIANSLVCDGMPNCSDEDYSDEQGYQLKIPLLNGNEAMTFSPYSQSPFISLDQNKEDDACIFLLSAPLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WE58</accession>
    <name>A0AAV4WE58_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinesin light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KLC_1</name>
        <name evidence="10" type="ORF">CEXT_11321</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016076">
        <property type="protein sequence ID" value="GIY81072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WE58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019894">
        <property type="term" value="F:kinesin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45783">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45783:SF3">
        <property type="entry name" value="KINESIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY81072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16348" checksum="055EB73ED7EDC16B" modified="2024-11-27" version="1">MGYIAKGSYEIAAPLCKTTLQDLQDKYGPEHPDVVAMMDIITIVYRGMQKYKDAAKMQLEIALTLNTLSALYGKTGKVEEAEKFCRKAVEFRKRVLGKTHADVGKQLCNLAAICCHRKQCNEAVDYYKEALEIFQILLGLKILIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEJ9</accession>
    <name>A0AAV4WEJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_653191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015924">
        <property type="protein sequence ID" value="GIY79725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10489" checksum="0520FD5B0E5FA4AD" modified="2024-11-27" version="1">MCIVGIQENIPFRALGDGSALKSGFLQRMHSQSSWQEQSPSAAPVNRSQGGIHVEDPLLIKSPPNLSSLADFEILDSPLRFSLKPGLFSLRPGRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WGZ3</accession>
    <name>A0AAV4WGZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_381621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016058">
        <property type="protein sequence ID" value="GIY80853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WGZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="18205" checksum="9BD00A8158F84602" modified="2024-11-27" version="1">MRIRELIGKYHSWNHRSGRHNWRSDLNEKNGPAQSLQNLRCGLFASEKRSLARTGAFPNFFSRKSEEWEEEFLLPLLLYSSSQKRQPKTKENRSPRVYVSFFALLLLLFLPFFPVEEIKLNAPLFFFLGEFSREGKFIPGGFRECLEGMRYSGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WP80</accession>
    <name>A0AAV4WP80_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pleckstrin homology domain-containing family G member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLEKHG1</name>
        <name evidence="3" type="ORF">CEXT_564341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016554">
        <property type="protein sequence ID" value="GIY84730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WP80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45924">
        <property type="entry name" value="FI17866P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45924:SF2">
        <property type="entry name" value="FI17866P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="906"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY84730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="961" mass="108524" checksum="B732DD872A69D7B7" modified="2024-11-27" version="1">MILIAKKKEEGILSYKTHIMCSNLMLIESIQGEPLCFHVIPFDNPRFQYTFQARNIEQKREWCLQLKRVILENYNAVIPSHARQLVMELGQSKQGDSALEKSHTKRQLSAPEYLEKRKQERRKSELNLNRTLKLKKVLKKSDSSLNKNNHANNRHKNNENHENWKSHDKSTWTKSQEDVCLKKRWLLGNLGNKENLSDCSSNAASSVPFSRSSRVRHSLPEPSLNQRTVSKERRFRPSWRTWNSVPEETTDTENEELDSKRYPDYCSPSLSYRDRTYSEASEEAFDNNGEYVTFFYAHAYATRDMHNGELESLRNGIDMDNTFSDIEDKATETKSPPSKFDSKCTSDTTKDYKSERQKDQDSESGSSVSSWKQNSAIRRVQSFTGMAKARVASLQHNISFKYHSSSNSEPKSKSKKFSYLPPNGICMLPPDLKETSPTTPAAWLKQQEEHLAESGKKSGSLPRSFQLASENAAGIPEMKPAALNDNVCRMRLRMDGPRSLHSEQRPFTIASDKPSHADFGDDLDYVVLDYSHCTSSEYGFPNHIDGYEQDTTTGCTNTPAVSMENVHSIHPELKIYHQSASKYATLKHIFSHMGSKIAGFKANLVSPSSHDSSNHEQHSRSHSEPSKNDFKRSESHSSIKSENELNSKLFPVKIAHSVAKAYSSVMRHKKKHELKFSDKKSALKKDKISIGSYKSESSLIGARMAQPLESEYSVPKLILPAKTFKDLRPDSLFSESSNATSSSDGDKNGTNDGSEYTKIDADDTVSEASDTSADSYYERTFDAIENALAHDIFRDSAIYSDPEDADFSVENPNLMISFEEMNPDKQVNNAVCYQNGDADCLSPSSPKIMCARRVNQAILDRLRILEENVKFQNEEASSIVTKSKAPNQKRLDLDKWGTIVLNKDFDESETSSEHSASTVNTVMESGNKASKANGSVNCRSPPRVKGWVKHVVEKLQGENQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WT71</accession>
    <name>A0AAV4WT71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_193701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016733">
        <property type="protein sequence ID" value="GIY86062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WT71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14787" checksum="FB772FDAD298B689" modified="2024-11-27" version="1">MDGWCPGITGQVEETRNSSINTAGALQGDRADRSTRPQKGCSTFGALEENPGIYPPSTKPLPQILTSISGTLFKFAPLDPEAQLACRKIRPCMQSTGKNGSHYLNPKENLNHARTLGSPLMRRHDRRQRWQAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXP1</accession>
    <name>A0AAV4WXP1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_788401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016876">
        <property type="protein sequence ID" value="GIY87038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXP1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8348" checksum="18864B42D05DE281" modified="2024-11-27" version="1">MTWADKSSTGFNEDGAIVQIAFRMGLKDDYFFHLCERKKKSIFVPPENRERNAQTIPLSTSGVILSVQTDVLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X0Y3</accession>
    <name>A0AAV4X0Y3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_587001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017046">
        <property type="protein sequence ID" value="GIY88303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X0Y3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10100" checksum="7BF04F0D900DEA5A" modified="2024-11-27" version="1">MGLAFYKPGSKVSLDSRSCPEKTSRWVWRSTSQAQRSVWILDLVLRRRHDGFGVLQARLKEQKCVWILQNKISTRVSKTSNPLRDPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3C0</accession>
    <name>A0AAV4X3C0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_353811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017145">
        <property type="protein sequence ID" value="GIY89042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3C0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11590" checksum="7BF8658C8BA6DE6D" modified="2024-11-27" version="1">MTAMNLDFAVSRIKVKLGHKRWAGLCFTFNSRIKVRGHSRKLFPDPYLILLAGKCSVAVTNGPPLNLPVNEWALRREFLRKSRSQKTVSERIRNLVLVWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAZ6</accession>
    <name>A0AAV4XAZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atp1a1</name>
        <name evidence="8" type="ORF">CEXT_168281</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017494">
        <property type="protein sequence ID" value="GIY92081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF13">
        <property type="entry name" value="SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY92081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9438" checksum="16B0D3C010162AF9" modified="2024-11-27" version="1">MGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEISPFLLFILADVPLPLGTVTILCIDLGTDMVPALSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDL4</accession>
    <name>A0AAV4XDL4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_46041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000087">
        <property type="protein sequence ID" value="GIY92056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDL4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9133" checksum="3425A52998B06A1E" modified="2024-11-27" version="1">MMVNSFTRFGSFRGGERLQTGRDRSPPDAGRNAGWYHVLREPMAVRLASLPLHGALFWREDSGQLEKGSPNYGPRANLQME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XDY3</accession>
    <name>A0AAV4XDY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_392281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017645">
        <property type="protein sequence ID" value="GIY93235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XDY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12145" checksum="96CA72210D95D1F2" modified="2024-11-27" version="1">MSCLLEFVYLHGHKGLKASSVYERMSEIAASPLAFLCPTPSPTPRVSLCLQTQSDVVTGSDSSPFFPVRCPEHTPPPPQQNRVSLWTKRIAEGLVGMSQLLSGLADSVMEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHR1</accession>
    <name>A0AAV4XHR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_732001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017791">
        <property type="protein sequence ID" value="GIY94496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043741651" evidence="1">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11423" checksum="75692C3E3D7BE862" modified="2024-11-27" version="1">MWNLARSVCSVCIFADAGAAVAVRGEGEDEDGAGRGRMNVGDSAWIRKLADTCAGQLDGADRCRTILFTKIKTGQNSILINDNVLPHIVYLVNKGYSSDSLFSQGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKD7</accession>
    <name>A0AAV4XKD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_189491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000548">
        <property type="protein sequence ID" value="GIY95562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9075" checksum="4179905A81198CCE" modified="2024-11-27" version="1">MRYINTARHRELRIIPLANIGLSNNPKTRIPPPNDIDNLPLSPRTSRGGTDHVTTTHRFESGRAITEAIPILCSLIQFSKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKN8</accession>
    <name>A0AAV4XKN8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_284271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000559">
        <property type="protein sequence ID" value="GIY95667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKN8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10784" checksum="5A749AAA83785688" modified="2024-11-27" version="1">MASCPARQISAIKRRQSMSEDEASFTCDYSRLSLAETVFSMTYRRPPKSVGQKERYREWNGISLNQEQSPMVCKVYRSWISCRGKCVFQVVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQK4</accession>
    <name>A0AAV4XQK4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_617031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018153">
        <property type="protein sequence ID" value="GIY97347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11537" checksum="CE1C397079DB19FC" modified="2024-11-27" version="1">MRRKVTHLEFQKYGFIGVIGRLTRELGSILLLPEKEHICSGQKKSYLFIWKLEDFLRFATVNSIQGFSLFSSFLWEKSPFWLRDCVVRYGNFLEILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWM5</accession>
    <name>A0AAV4XWM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018283">
        <property type="protein sequence ID" value="GIY98384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12002" checksum="E0083F9D44D8829C" modified="2024-11-27" version="1">MSNANCRVMRNGLALDLPSSRIGLELPLAVPFGSNRKKPQDVFLGTKKIRCSTGRLFDAELMDFLALILRGSVCVEEPSEKAIKFRCRVASFLDGGPPLSVRGSFLKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWQ0</accession>
    <name>A0AAV4XWQ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_799261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001048">
        <property type="protein sequence ID" value="GIY99432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWQ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16306" checksum="10C1603294B61B37" modified="2024-11-27" version="1">MHHHRNFPATQPLQIQPELFFLSHNKQDLVLTKFVESVDAGFVGDELEEAAEEIPGGFVADDNTGFFEDGLTGFVEDDLALDIVEYCDNLFEMTILIVGLLNHVTFMITFLAMLLLHLKSSHTYLNCSASILKMTKSNCLKLKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6P2</accession>
    <name>A0AAV4Y6P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Trimeric intracellular cation channel type 1B.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">tric-1B.1</name>
        <name evidence="14" type="ORF">CEXT_221401</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001332">
        <property type="protein sequence ID" value="GIZ01656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007866">
        <property type="entry name" value="TRIC_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12454:SF11">
        <property type="entry name" value="GH25683P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12454">
        <property type="entry name" value="TRIMERIC INTRACELLULAR CATION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05197">
        <property type="entry name" value="TRIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="6" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIZ01656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="287" mass="32166" checksum="2A1685AB19E12A83" modified="2024-11-27" version="1">MDPEAFLEIANQISRLQMYPFFELAHCLIMCMYVKEDLAGGAHLFSRKHPLACWVSCMLSIYGGAMFASFLLGEPILSSFKNQNSLLLATGAWYVIFYMPFDFGYKVFKFLPIKLVLALMKEVIRCKKVHDGVVHAAKIYPNGYVIMIIIGTLKGNGTAFLKVLERLLRGVWTPNAIELIQMSFPTKACIAASIIFVLDKKTDIISAPHALVYFGIVIFFVYFKLSSMLLGIHDPFVPFENLFCAIFMGGIWDTLQRLLTPASKGDQSSVKTDTAKNGKTESAKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6W7</accession>
    <name>A0AAV4Y6W7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_263511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001538">
        <property type="protein sequence ID" value="GIZ03012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6W7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14406" checksum="1C6D06EBFF0E8FD6" modified="2024-11-27" version="1">MRLGFPTLCSRYNNYIYGNSTLIIYAFELSRLAFATATVSPLFWCQKWDTQKAIPRMSCVPIFCRTGGARQMGMGTNKNRKPFMELARFMAHLTLACQPPSLDEERFGFKDWRGKNKNCRQEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y710</accession>
    <name>A0AAV4Y710_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Zinc finger protein 593 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CG3224</name>
        <name evidence="16" type="ORF">CEXT_164781</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Associates with pre-60S ribosomal particles; released from the pre-60S particle very early in the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001557">
        <property type="protein sequence ID" value="GIZ03133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y710"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="15">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00057732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00065398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00068297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIZ03133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14262" checksum="6E876C4AF8DC6836" modified="2024-11-27" version="1">MTRYSRKKGNHGYSAKRKQLKMKRRNKDLDEIDNDLEPKNAEHLLNQPLDLDVAGGAQHYCLHCARYFIDNTALQGHFRTKVHKRRLKALETEPYTIQEAEAAGGIGKYVPPKKRKMETQKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7R0</accession>
    <name>A0AAV4Y7R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Svep1_18</name>
        <name evidence="7" type="ORF">CEXT_574891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018824">
        <property type="protein sequence ID" value="GIZ02549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050350">
        <property type="entry name" value="Compl-Cell_Adhes-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19325">
        <property type="entry name" value="COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19325:SF560">
        <property type="entry name" value="SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="Sushi" evidence="6">
        <location>
            <begin position="152"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="6">
        <location>
            <begin position="267"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="6">
        <location>
            <begin position="389"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="6">
        <location>
            <begin position="505"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="6">
        <location>
            <begin position="622"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="154"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIZ02549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="754" mass="85213" checksum="0973A3750D936A57" modified="2024-11-27" version="1">MFFNVLSDTKFAGTVLFFKSDCSGRDIGYECHLVCKNGGRIIGSGYIKCLPNYTWTSLPDCTCPVPHVTNNLEFKEDCSKRKLYLSTACSRKDLKAKFGDCMSKKRGEKCFIECKDKDSKLIGDDFLLCRRNAKWGASQKGEWYDLPVCSESYCHPPNVAGTVVDLKENCSRKRMGDECQLLCKHGGSIIGNDRIKCLFNNSWSTLPDCTCSSPHIKGDLELKEECSLKQRGGRCAVGCRGNDTIHYITCQNNTMWSKMPKCGKFTWTCDVPELPVPLLSFEESWKECEFKDYGDICNLVCLGGSQMVGSGTLICQRNGEWTAIPDCTCGTPILPFDFETKENCTYKKAGENCAIGCKDAVSVSSRDYITCVETRRWDFMNHVLECVKSFCTLPVIPQEILKFEENCMKRKVGGTCRLSCRAGGSMLYSVDYITCFPNDTWSTLPECTCPDPYVTEDLDILENCKKKPNEVCAISCKNEYEKAVTRYITCQNNTLWSSLPRCSKKFCPTPTSGWILGYVKNRKYCTHKMAGEICQVYCIGGGNIIGKNILTCQENGEWSPFPDCTCPTPVLTKDLEFREDCSHKRFNERCLLKCKHGLSMDKQYILCDNFRRWESLPVCEKPSCPLPILPDKNIVTYKDDCSVKKPGDACHMICIQGGYAHLDASRIVCRQNLTWSKFKYPICSCSVPILTEALVFKEDCTSKWPSQFCLLGCKMELLPVKNTSYAKTIANGIHYLHVMDLQLLVPIQFYKKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y814</accession>
    <name>A0AAV4Y814_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_592631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018898">
        <property type="protein sequence ID" value="GIZ03064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y814"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11400" checksum="6BB31BAC864A046E" modified="2024-11-27" version="1">MGERVTPRSPTTHIHFQNTTRYPFQKKKKKERKKRAEVIGRSFSKKNESLHCLGRTEICAFHSLAIHFKKCLFLFKMVRWMRLAKNVARKGIGKLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9Q6</accession>
    <name>A0AAV4Y9Q6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_645691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019001">
        <property type="protein sequence ID" value="GIZ03828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9Q6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11958" checksum="AD9E11A6A7E28B46" modified="2024-11-27" version="1">MSRQGERGPPNAAESSKNGKRNLEMGLPMVISIINILSCSLQLVFGQRFSVGSFVTRRRGELSCFSDWVLYCCRGNGKVVVVGSKQEVWRFWVVCMGWGKLWVELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YC01</accession>
    <name>A0AAV4YC01_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apolipoprotein D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">APOD_2</name>
        <name evidence="12" type="ORF">CEXT_278061</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019169">
        <property type="protein sequence ID" value="GIZ04937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YC01"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19437">
        <property type="entry name" value="lipocalin_apoD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.128.20:FF:000003">
        <property type="entry name" value="Apolipoprotein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00179">
        <property type="entry name" value="LIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043116376" description="Apolipoprotein D" evidence="10">
        <location>
            <begin position="19"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="11">
        <location>
            <begin position="35"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIZ04937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20552" checksum="3C545B2D4FD60323" modified="2024-11-27" version="1">MHLLLLGLVVVAFGFTNAQKISVGGCPDVPVKENLDVKQYVGEWYEIEKNPVPFEAGLKCNKATYGDEGDYVSVLNEGVSIRTGKPSSIQGKATIPDKSVPAKLKVKFNSMPFSADYWVLDTDYKQYSVVFSCFSVLNLFNAEYLWILSRTPTLDENIKENIYKFLDEHKVNRARLAPTVQDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YE10</accession>
    <name>A0AAV4YE10_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">CEXT_764931</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001770">
        <property type="protein sequence ID" value="GIZ04631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YE10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF194">
        <property type="entry name" value="INVERSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="11" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIZ04631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="8935" checksum="1265571AFEE90115" modified="2024-11-27" version="1">MKLLLKIGADAETPQCLTTLLHIACIFDEVECAEILLNLRANVNTVVTNEMTPLYVACECASIPCIELLLKMDTDVYFATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YEE9</accession>
    <name>A0AAV4YEE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tuftelin-interacting protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TFIP11</name>
        <name evidence="3" type="ORF">CEXT_456801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019113">
        <property type="protein sequence ID" value="GIZ04614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YEE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022159">
        <property type="entry name" value="STIP/TFIP11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12457">
        <property type="entry name" value="TIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="132"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ04614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="263" mass="28988" checksum="253E0F59D16E83E7" modified="2024-11-27" version="1" fragment="single">MLFATLLSCAEDLSTVRHNLTKKQQIYGVFASDDSDEDERHGFGHKNSSSSAQINFVSGGVRTVGEKPAKKESDEEKGSTDDEETVKPLPKKSYSFQKSGFGGSRNSRQIAGLRSFSKNANNNEFGGWEKYTKGIGQKLLLQMGYKPGKGLGKSLQGITTPIEAKLRKGKGAIGLYGPEQPTMSRVKGPGVIEEEPVIEEESKTRQRQWKKNTVERKTKVEYYTQSAEEAAQEGISKRFRGDISGLSSVKVIDMTGPEQRILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M381</accession>
    <name>A0AAV4M381_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_373961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001829">
        <property type="protein sequence ID" value="GIX66907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M381"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="14082" checksum="72DDE0528033A484" modified="2024-11-27" version="1">MLLLYISIINRGSRSYARQYLNSIPSNRRSIVRRSRKVTLPARIVIDERCEFHCWGRHKFRHVLPLRTSQDRYVSLLHPNREPIQISDILLVPRTHYSPMEHGPSVWRGRVLIEKSANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M688</accession>
    <name>A0AAV4M688_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_273431_1</name>
        <name evidence="3" type="ORF">CEXT_420941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001878">
        <property type="protein sequence ID" value="GIX67443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M688"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX67443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="366" mass="40499" checksum="F79427E9D8934873" modified="2024-11-27" version="1">MTVLSISSVSNRVSALMWFRKLASEGFGVYFGTSPSLRITPQRKAKGARNLAVLSTLTTMTYAKKTVPKTKRTPYVFIIGTSVRGFFDNRHQFAAESADDMQSWIQAIRGAIAEARVSRRKPSRKRHLEGKSPDLSTSSQESEGTSTACLVNATKDRARGPQGRRLPNRKSMMPASRSVEEADIRQRSGPREGGFRQPEEQFGVRPPPAKEEIAPQKPHKKVGNLMGQHAALTKELEMRLKAGRTPVHRRPPSESEEDEVQGTGKLDQLASKVSSTSESLAALEERVGALTRRVDAGRERSEKQVGDILLQVTVTQQEAERINAECKRALVDANKAKAEYQLLVKECKEMLAKLNSDSDSQQNCVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6U5</accession>
    <name>A0AAV4M6U5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_234621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001884">
        <property type="protein sequence ID" value="GIX67527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF40">
        <property type="entry name" value="REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="1">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="15849" checksum="E21DE3123CE530E9" modified="2024-11-27" version="1">MAKELIIEKLERKFASLTRSKESIQAVSSWMINNDEFYEVIVEQWFISLSKDINALTMFYVANEIIQSCVRRKAPQYRDAFAKVLEKAVCLAKVKEIKPDVCRLLSIWREREIYDEEFYQKVLNKLNSEVDAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAK2</accession>
    <name>A0AAV4MAK2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_148983_1</name>
        <name evidence="2" type="ORF">CEXT_201251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002035">
        <property type="protein sequence ID" value="GIX69280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAK2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="23247" checksum="7F8EC23A76DA6ACA" modified="2024-11-27" version="1">MQELTTAISESSLNKYPGPDGVHGTNDQEQFGFREGHSTTDQVLYFCQRVRDAHNRSPQITLWQPSLIFLKPSTWSGYSALRRSSPKGVKWVFFADDVVMWDSGTDLQKLEDNLNSTLEDLWKFAENHKLSFNPTKSTTHPGICNFCCASNTNLQKLDRVQLSAARVITGLRNTCPNDRVLYEADLQPLSLRRCLFGEILWQTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDL3</accession>
    <name>A0AAV4MDL3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_208241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002095">
        <property type="protein sequence ID" value="GIX69930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDL3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9604" checksum="E442CA8FD3666DB6" modified="2024-11-27" version="1">MSPDSAEESKGPPSPRTSSALSSATPIPTNFGDFIIVQMALIKPPSPVHPHPGAFVQRRNTPRNGSLLFKKDLEMEESQLILLLVITAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFF3</accession>
    <name>A0AAV4MFF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019727">
        <property type="protein sequence ID" value="GIX71143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9145" checksum="745A0221F0EFC8FA" modified="2024-11-27" version="1">MLLMAGICFRPPGGHPFPANDIHRRQKLDPLPPLFKTPTCQTPVEGKTVLKVEGRRAENLFFHECPNIPYGSSTNEREWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJH5</accession>
    <name>A0AAV4MJH5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_505781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002176">
        <property type="protein sequence ID" value="GIX70949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9798" checksum="38AADB807AD31AFB" modified="2024-11-27" version="1">MLMAWLSKILMKILSNCIKRKRLAVVAFLLISRIGSVWGCVPFAKVPLDPLRKQSLHISGAQRSAEEMWSYFCNSHSTVKYLTSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MLM6</accession>
    <name>A0AAV4MLM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 13B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS13B</name>
        <name evidence="4" type="ORF">CEXT_625431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019843">
        <property type="protein sequence ID" value="GIX72371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MLM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039782">
        <property type="entry name" value="VPS13B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12517:SF0">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12517">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Chorein N-terminal" evidence="3">
        <location>
            <begin position="3"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX72371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20854" checksum="064039B6013DB504" modified="2024-11-27" version="1">MFSLWGGDAVFCNLDLRLDVLEQELQLPFTFVNGHIHELRIHIPWTKLGSEPVVITINTIECILKLSTDNDDQDSDRQKTLNLKKTFYEMLVEKSKLIKTHFYIVALLLGVYIVFINRLTPTLHNGNNITSQENAKNYEDDSEIKAGLPEEESGDTEMFSQDDSWLVGLVFLCLMLELYGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMT4</accession>
    <name>A0AAV4MMT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_90521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019819">
        <property type="protein sequence ID" value="GIX72089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX72089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="11014" checksum="B946E4111A9EB938" modified="2024-11-27" version="1">MLTFIDSVHWICHQNKWIPQHFYFLSISGNVKDYVIHIPTSSLSELTCSNMQTNRTVRNHVFDDYKVYSDTHVEVAESAHLTSYLAHEFLQKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MZA9</accession>
    <name>A0AAV4MZA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytoplasmic dynein 1 heavy chain 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DYNC1H1</name>
        <name evidence="13" type="ORF">CEXT_808051</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020310">
        <property type="protein sequence ID" value="GIX77254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MZA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain linker" evidence="12">
        <location>
            <begin position="46"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX77254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="244" mass="28968" checksum="27B09D035741F570" modified="2024-11-27" version="1">MQWDIYHCLNPNLHALKEDRDNVMRAKEALELQEPGILSATDERLQVALEELQDLKGVWSELAKIWDQIDQMKEQSWLSVQPRKLRQHLDSLLNQLKELPARLRQYASYEYVKRTLQNFTKVNMLIVELKSDALKERHWKQLMKQLRVNWVLSDLTLGQVWDIDLQRNEAIIKGVILIAQGEMAFRRILKQVREAWQNYELDLVSYQNKCRLIKGWDDLFTKVKEHINSVAAMKLSPYYKVHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N640</accession>
    <name>A0AAV4N640_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020472">
        <property type="protein sequence ID" value="GIX79151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N640"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11192" checksum="DCA95EF5AEF7D86A" modified="2024-11-27" version="1">MSNKRTGKPCSFDIEKKQEGIIFFEVNGIFLNSIQVLIAFGNAENTTYLTAGERDKSEALVQLNCRDPSPTEFCQQLAAEPAFRPRAFLADLQMALRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8Y3</accession>
    <name>A0AAV4N8Y3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gpp</name>
        <name evidence="2" type="ORF">CEXT_514081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020590">
        <property type="protein sequence ID" value="GIX80388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8Y3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="561" mass="62548" checksum="B9762019BA48A67C" modified="2024-11-27" version="1">MEKLPTKMLLLIQNPLTRVLITKRNPNTARSIPFRLGKSNGVTKDRSSLSSQSQNQKWQAKVSSGFDKLLALAATQLNHANREYKCNQSKMMKDIPKSNQFLPYSKSNGFVIGDQCKPNKDSNESQKNTISDPRISQFETHEPTGSNINRVRKGPRTPPDTPPRTPSVSPDRSPYFRSNSPISVESLISRRSSSSPQYRSPSRRNSKDRSRSSSPYSSRTGSVEKNLQKYSRNSKSSSHEDESNEKKSNSKHDYKYKNNKSDSRTWTKEQESTNPKVTHSNDKGSKNESSNSEKSSLSSTKNKEVMRQLDFISQQTKDVLAHAPNGYSVVMTPSPLHAIYVPTAGVCNQPPIPPQTQNLNSKSTNFSVTNACGPTLSTNPLLNFTIPPPNFSMPPPHPTSSSVNMPQILPSQQQVQPIQLPDVTVPPPNMMSVPSFLSSSNLPSCPPQLEPAVPNNHVYRQNNQSHPPPLPPTMAAASSFNTIVQSQLYRANQKPLSNGTTSHQLDYRVPQHCTLPGTGSSNYYPVLQEQEEFYSAHWEEEILLSDLELPKLYLETISKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NH52</accession>
    <name>A0AAV4NH52_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_157401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003268">
        <property type="protein sequence ID" value="GIX82784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NH52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11762" checksum="C3E86376B352835F" modified="2024-11-27" version="1">MGRYFRGQTKSVVIMTWRKLGDRIKDKRINKHEDLLIPSAFSPEINWWLLFNKKTIISSTLSVRDCSLERIFRARKWLLLMSSYSVNNCYCMDEVCPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSA2</accession>
    <name>A0AAV4NSA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_176261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021159">
        <property type="protein sequence ID" value="GIX86645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX86645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="183" mass="20810" checksum="55B806635AB3D589" modified="2024-11-27" version="1">MVASLITKETKSQGKPIFKTTELCHLKKQENDSSGIIDAKSNRLVLKIERLKDRIYIYIYLRTPNSLPKRENSPPEYHRQAGKISIPPDENGKNSVFKIPPWKKIFRKEGLDAVKARRRKKNGILAGIKVRKQNEKIVESKYQKVKSHSVLWAFSLNQSGTTKSGKGAWSASNFSKYIPASNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P397</accession>
    <name>A0AAV4P397_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chaoptin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">chp_5</name>
        <name evidence="3" type="ORF">CEXT_586861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003961">
        <property type="protein sequence ID" value="GIX90681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P397"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF96">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX90681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="233" mass="26069" checksum="8EB783A75DC8474F" modified="2024-11-27" version="1">MRGTTRGGRAGQKKQIALSEDNSLNGTGLWKLQINNNLLTDLPPNALAGLEKTLSILDLSTNNLVRIPKEAIQNLEKLSNLNLAGNKISFLHNDDFRNLEFPEDSLLQIKDTLQFLDLTGNQIESLNFSSIEYLQNLHYLSLSQNRMFLPASGEELQLPKLISLDLSYNILKEFPTWMAHHLPLSLEELNLANTSLEAIPTLSACNILVLNLSSNSIQTVEQEGLEQLKKVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PA27</accession>
    <name>A0AAV4PA27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_23691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021719">
        <property type="protein sequence ID" value="GIX92853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PA27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="15150" checksum="DFBDD0C3829DAF75" modified="2024-11-27" version="1">MCLRRPNLDARQSRAVSLHQRPGDATHYESSRLASTMDVPFRRTCGPRFTFVFCRRQRALLLCVWKRAKLLQKFQQDLWDNYRSLSYLQLKLFLVMMRSDWLRANHYKKSIFSFMIEALLHSNCFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDB8</accession>
    <name>A0AAV4PDB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_85361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004319">
        <property type="protein sequence ID" value="GIX93980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8742" checksum="269E5971EAB839AE" modified="2024-11-27" version="1">MGGKFFFNGSQVMLGFLWMKRIPLDLPRRIGIDCFHMLTGHNYLQQYLNKIGVTTSASCRLCEEDSIKDDILFVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGD1</accession>
    <name>A0AAV4PGD1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_180051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004460">
        <property type="protein sequence ID" value="GIX94979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGD1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12999" checksum="7AD8436E226C93FB" modified="2024-11-27" version="1">MQCGSGNDDAVPNVNDDFGGIDIERTGIFLICLVGSAQASPDYLRMILANYLSNTQDMETNSPSDNLMDLRRDGFISYELKYRSRDPAGLHFRQEYSDGSGLIKGILNLKDEKGDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PNP0</accession>
    <name>A0AAV4PNP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_387561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004995">
        <property type="protein sequence ID" value="GIX99022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PNP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20205" checksum="073915D3229154FD" modified="2024-11-27" version="1">MTYMEEGAHVPLINARSRSTGDYEEMMQEGMLVIHTQSEAALKEKYNTSFQEEAFTHNNRGRNGQCRFLVPPQLQFGSKIFPESSHLSLSPSNIMKGILDNFFTVIIPDFDTRVLKVTEFLTFPDYLYCQRRCNFLHASFTQLDYIRLRSKLEDYEVSQRQIAAKHNKNSNGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPU2</accession>
    <name>A0AAV4PPU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_458881</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004893">
        <property type="protein sequence ID" value="GIX98348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="8" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="9" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX98348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8407" checksum="3424517B4D1DB504" modified="2024-11-27" version="1">MLQKYGADIDAISQNKVSPLYDACYQGSIVCAELHLNMGAGVHTSKNWRTSGIHEACMQDKWNVQGYYLYMEQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTY4</accession>
    <name>A0AAV4PTY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_51901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005038">
        <property type="protein sequence ID" value="GIX99380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18628" checksum="C0E703BDC4480CD9" modified="2024-11-27" version="1">MVYSHVTEGSLSINDSNSVQGNTNAVDPISQKENIIFVYPKTEEDTNLDNQISEEEFIIVADASSDEESLDSADPNFEEPNYVKESINVVDPSSGKNDIYSNSEEEIIHFMNPGFEMEGVNAVDPILRKKSINIVDSSSEEESLCIVDSSSEEERKIQVLKRKAYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PVA0</accession>
    <name>A0AAV4PVA0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Probable RNA-directed DNA polymerase from transposon BS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RTase</name>
        <name evidence="2" type="ORF">CEXT_109981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005331">
        <property type="protein sequence ID" value="GIY01523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PVA0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="278"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="503" mass="58222" checksum="63659B9D54278FC3" modified="2024-11-27" version="1">MQPQTARHPAVEYQKHVEQRRNGIVVRVLEANWTLFEKNLIEQLKKNPITEDLENEWFVFKHSIFTAAEGAVPRGKHKKTRPAFTSDSQDLQKLLAKREHLLQSHNLNDNTDARIELNKINAEVKWEYCSIKQNNWQDLCKSLDYKTPNTRLWRLAKNLDKIQPQVENTNSIIGTNGIPIVNDKEAADALGNYYSEESKLALGRENKKTGRATRKLIRSCRAPASNELFNDPITSSELLYAIQQLDFKKSPGPDGIHGQFIVNLGSCATKRLLHIFNLSWKLGRLPRQWKTAIVVPIRKPNKDASCMGSYRPIALTCMTCKLMERIILRRITFHLMNRNMLPQEQYGFRKGHSTIDQILYFVQRVRDAHNMKPSRHTMAVFLDLTKAFDKVWKNKLLGKCFSEFDIKGRALPWLSDFMKSRYFRVRYQNSLSEIFKTYQGIPQGSVLSPTLFSLYLTGIERVVSPCQIGIFADDIIVWDHNSDLTKLEKYTQRHLGENSTLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW71</accession>
    <name>A0AAV4PW71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_516521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005372">
        <property type="protein sequence ID" value="GIY01823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13771" checksum="7669853BD75F8F22" modified="2024-11-27" version="1">MFEDIEDILSPFMLFLFPRMLAVFFIFIYQMLYSVRLRNLPLINMSIPYFIINAVLMIIIVLSADRVQKKADKFRLSLYQYLELNSVLNGEYLRILEDWRHLKLTAWGVFAIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PZI1</accession>
    <name>A0AAV4PZI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_479381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005293">
        <property type="protein sequence ID" value="GIY01286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PZI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10308" checksum="5D71429AB809E1AB" modified="2024-11-27" version="1">MPIAIESEYFPDIGNQCLVQEVEHFGKIGVLKNQRTIVCDIDDKCTKRDTTSETWRRRQDNSFFTSRRVNKRDLPLIPKSSKKASYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q293</accession>
    <name>A0AAV4Q293_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005460">
        <property type="protein sequence ID" value="GIY02594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q293"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="15946" checksum="683CDA19AE99E3F1" modified="2024-11-27" version="1">MTAAGLVSPLVSQTAVRTQSSGNGAAWTIVPAHSVHKMIAEFNELPMEGFLPMVYSERLAGEGKNLGQARGSLASCSDFQSSLAGSGGSWIPNCHPYPLLWCQCLAGRTCAWYMHGDTAARLFAALTIAWVSQWRYGACVPLRYMSKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q2E6</accession>
    <name>A0AAV4Q2E6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_441401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005561">
        <property type="protein sequence ID" value="GIY03301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q2E6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16484" checksum="4EDB02747EBCA74D" modified="2024-11-27" version="1">MRQQLKYFEVQLEFNPDPEKTASIQAGLLTASQEIDATIAKLGVPLAKLPTTPEETSRIIKAVTETRNLPTTPRLQQQQHTRTLTQSQSNRSNVKISSDPQLDNPRVRRSADKDGFIPSSKMKDNGSRSMPITNLKSLQLKAKKLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q3U6</accession>
    <name>A0AAV4Q3U6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_685941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005642">
        <property type="protein sequence ID" value="GIY03952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q3U6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9601" checksum="5EA71F6EC59C77CB" modified="2024-11-27" version="1">MTIVEYVGILTQRIYVAYVEATVGKRFKSNGYSRKVVVIVKIEEIVMAITESTGIVISIVDIVMVIIEYSEKILDIAEYIEIIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q4H7</accession>
    <name>A0AAV4Q4H7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol transfer protein alpha isoform</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PITPNA</name>
        <name evidence="2" type="ORF">CEXT_389971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005537">
        <property type="protein sequence ID" value="GIY03092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q4H7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008525">
        <property type="term" value="F:phosphatidylcholine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08888">
        <property type="entry name" value="SRPBCC_PITPNA-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.530.20:FF:000025">
        <property type="entry name" value="Phosphatidylinositol transfer protein beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001666">
        <property type="entry name" value="PI_transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055261">
        <property type="entry name" value="PI_transfer_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10658">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10658:SF11">
        <property type="entry name" value="VIBRATOR, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02121">
        <property type="entry name" value="IP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00391">
        <property type="entry name" value="PITRANSFER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylinositol transfer protein N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY03092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="31337" checksum="227248D601C89A36" modified="2024-11-27" version="1">MIIKEFRVVLPITVEEYQVGQLYSVAEASKNETGGGEGIEVLKNEPFDNVPLLGGKFNKGQYTYKIYHLASKVPAFIRLLAPKGSLEIHEEAWNAYPYCKTVITNPDYMKNNFFISIETMHCPDAGDQANAHELPPEKLKQREVVFIDIANDPVEHRDYKETEDPTKFKSEKTGRGPLVGNWQKTCTPVMCAYKLVTVEFKWFGLQNRVESFIQKTERRIFLNFHRQVFCWLDRWHGMTMKDIRDLEEKTKRELDEQRNKGHVRGTQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q942</accession>
    <name>A0AAV4Q942_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_777311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005640">
        <property type="protein sequence ID" value="GIY03903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q942"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="12938" checksum="C29EE65D9B6D17AA" modified="2024-11-27" version="1">MEMNSVLSLIAPHKSTEASKQMQNATECDSANEKRKVVARDWVSFDFSKAKLCWVLGAGRMFARRVFNMQPNICWCGGGSCAGLHVLGGVGGGIELSLRNARGGRSVIENLINVIARVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9G1</accession>
    <name>A0AAV4Q9G1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hypoxanthine-guanine phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HPRT1</name>
        <name evidence="1" type="ORF">CEXT_693331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005984">
        <property type="protein sequence ID" value="GIY06653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9G1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006178">
        <property type="term" value="P:guanine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050408">
        <property type="entry name" value="HGPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340:SF1">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="22213" checksum="EEE00E4F11115E87" modified="2024-11-27" version="1">MEPVSLESIVADDYKGYHPDFFCIPKHYQGALECVLVPGGVVKDRIEKLAQDIAEDIGSEPIFALCVLKGGYKFFTDLIDQVKKYNHYATRNTIRISVDFIRLKSHKEDGSSGDVQVIGIDDMSVFTEGLLVKRTKGNFYRPDCKSGFEVPDKFVVGYAIDYNEYFRDLDHVCIVNEFGKKKFASFYPSRNPVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QAW9</accession>
    <name>A0AAV4QAW9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_237931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005852">
        <property type="protein sequence ID" value="GIY05496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QAW9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY05496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11872" checksum="088E8ECFE25A892E" modified="2024-11-27" version="1">MFLFEKCVRSEGCKKGWLENHARRTKTVIGLVHGDTRGRGADHRKINEPSGDNGGRVERKKNAYRGWPQSRTARANPQPSERERNKVDKCRPTKRFPPVLFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QD10</accession>
    <name>A0AAV4QD10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_29231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005936">
        <property type="protein sequence ID" value="GIY06189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QD10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11463" checksum="8D0A7F8480D734CA" modified="2024-11-27" version="1">MPIQDLHQQDLCIQIRRKLHGSNSAPIADKKMALWFKDEERTNYKTAMLLSVETARELPGPSRSPTSPATKRRAHSPEREVSIKIISEQRSYTNFQGQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRI8</accession>
    <name>A0AAV4QRI8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_780061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006716">
        <property type="protein sequence ID" value="GIY11884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRI8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="48" mass="5638" checksum="6EB82735179C11E3" modified="2024-11-27" version="1" fragment="single">MPNLERSLWNKSYSFMRKAFLGLQLQLQFPPHRGVSLPTINFAILVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRJ1</accession>
    <name>A0AAV4QRJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_640291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006558">
        <property type="protein sequence ID" value="GIY10737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10556" checksum="6C830FF4D12C4CF6" modified="2024-11-27" version="1">MAVLSYPIKFIRTSLIDAKVRVSLQTANQKYLFTNKREKETQTETLRIYHRFYLAANVQFRNLSPSLLKNCPLPPQTAISADDPVPTSKQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R353</accession>
    <name>A0AAV4R353_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_597601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007095">
        <property type="protein sequence ID" value="GIY14508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R353"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8978" checksum="65A13883CB709F1C" modified="2024-11-27" version="1">MSIFEKTRDRSKAGNYERSTEYVNLPQRKPVFQQQISFQSAAESLSRLAIPQDKRCAACLARSASSLVAAAEIISNSVNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9Y6</accession>
    <name>A0AAV4R9Y6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_246241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007486">
        <property type="protein sequence ID" value="GIY17222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9Y6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043607440" description="Secreted protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY17222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9722" checksum="48B076DF5C624FA7" modified="2024-11-27" version="1">MAMLVLLGFLYGPVLRRSPRRYPFESESYTAKRGNPGPPDRSPSTHTVNVRARFSISEIKEAVLLVLICFACNAACRSPANLENLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RBP9</accession>
    <name>A0AAV4RBP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E3 ubiquitin-protein ligase arih1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arih1</name>
        <name evidence="3" type="ORF">CEXT_707291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007518">
        <property type="protein sequence ID" value="GIY17508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RBP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048962">
        <property type="entry name" value="ARIH1-like_UBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21235">
        <property type="entry name" value="UBA_ARI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E3 ubiquitin-protein ligase ARIH1-like UBA-like" evidence="2">
        <location>
            <begin position="56"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY17508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15735" checksum="6FA82C91B087985F" modified="2024-11-27" version="1">MDTGDDELYDEDSGNESSAEDEDELSISLEPETSSREKLDTEEFHYEVLSTEQIVQHMVDCIREVNTVVQIPPTITRILLNHFKWDKEKLYERYYDDDQEALFKEAHIVNPYKNHLHLRIPDLHPEQKNARFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RE68</accession>
    <name>A0AAV4RE68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_606381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007862">
        <property type="protein sequence ID" value="GIY20263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RE68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY20263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13276" checksum="E7B411B25A993435" modified="2024-11-27" version="1">MHAHIKGKLTTKSRRHCEGKYTTKSKSSRRSVPPTIILFSAAATTFFVQMEKFFLCFSSRIRIFSPASLGRGQRTDLDQSAREAANIKRTHRSCLPHAAVEKPFHGWFSVIGKVQVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RET1</accession>
    <name>A0AAV4RET1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_586551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007679">
        <property type="protein sequence ID" value="GIY18836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RET1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="13984" checksum="9B3CCACE2D5A50C9" modified="2024-11-27" version="1">MKSLSQQGKYPNLGINTHTDRTGRNICIKFISPPLKNCASCSPKNGQKGPAMQTALRYGYMASERIHSSQAGKHGASKCPLKEKSRRQRLASKTITAGGRREEKKKKSKKKKKKTSVKNGERLAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RH10</accession>
    <name>A0AAV4RH10_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_622451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007789">
        <property type="protein sequence ID" value="GIY19742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RH10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY19742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21651" checksum="69DFC09097A99DCB" modified="2024-11-27" version="1">MPTENFFDHLLDENSDFQNGQLIEDCMQRFDLDCDGFLNLRELCSLTDELFSDENGTSYEFPVLIAPVIKPTTALIAIDVQNDFIDGSLAIRNCPAGQEGFEVVPVINNLLETVPFDYVFYTYDWHPKITYPLLIMNLRNFHETSLIPQEKQRFSTLLSLKVLQQLNKKLWPRHCVQNSWGQNCILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RU02</accession>
    <name>A0AAV4RU02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD repeat-containing protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Wdr19_0</name>
        <name evidence="3" type="ORF">CEXT_426231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008266">
        <property type="protein sequence ID" value="GIY23358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RU02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039468">
        <property type="entry name" value="WDR19_WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15911">
        <property type="entry name" value="Beta-prop_WDR19_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="WDR19 WD40 repeat" evidence="2">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY23358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11493" checksum="DC062142EDB258F1" modified="2024-11-27" version="1">MIHLFLCWSGNSVYPPSIHRTTGIKDLHPDFSGTRILIIDSKGAAFVCNPLDSSLLAVPNFSSNVTHLLWNHSTVYKEYLLPLMMLKLIYSFIFVIVLKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S158</accession>
    <name>A0AAV4S158_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Speckle-type POZ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SPOP_19</name>
        <name evidence="3" type="ORF">CEXT_187011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008666">
        <property type="protein sequence ID" value="GIY26306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S158"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="11"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="351"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY26306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="474" mass="55045" checksum="6E60E37BBEDC219A" modified="2024-11-27" version="1">MSDILDLKEKVFTFSWKIKNFSYCVESIRSPEFITGNNRKWFLRVHVNKKNQIRCSLVRVKASESTTLDYEISILTCDGTPEVKLTEKEATFKKSKLAKNSQHRNALGRSLCVAKDIIHKSRRDSFLLNDTLTIKCQMWSSEDHFEARQAFVSSQLFLNATSRKHFPWPVDNLKKPFKSDKRNIPLFNSKAIKKSDKFFLNFTMVDEFNETKAFQIKVSRPGGKRRCTILKLFIFDINGKALDLVTEEFVFGKMKTQQIWQLQSVNWKNKITEIENYFQCSNLLFIMCEFVTYIGVVTKETSRLNPTDSVSSHSLESCGGRLVSDMDGNRSQCSEYLKNDLKQMLDDGIFCDLKLRVGTETIPVHRSILSARSPVFRTMLANHKSSDTVDVEDVEAYTMRQLLLYVYTGNIDDLQWENIAKLYSVGDRFKILCLKEKCVSLFKRNRDEFYLRKRIGRDLSSYYSTLQYIIASSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S2Z7</accession>
    <name>A0AAV4S2Z7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Frizzled-4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">Fzd4</name>
        <name evidence="21" type="ORF">CEXT_409471</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor Fz/Smo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008938">
        <property type="protein sequence ID" value="GIY28354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S2Z7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017147">
        <property type="term" value="F:Wnt-protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035567">
        <property type="term" value="P:non-canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07448">
        <property type="entry name" value="CRD_FZ4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.2000.10:FF:000008">
        <property type="entry name" value="Frizzled receptor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015526">
        <property type="entry name" value="Frizzled/SFRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000539">
        <property type="entry name" value="Frizzled/Smoothened_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020067">
        <property type="entry name" value="Frizzled_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041765">
        <property type="entry name" value="FZ4_CRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309">
        <property type="entry name" value="FRIZZLED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309:SF99">
        <property type="entry name" value="FRIZZLED-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01534">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01392">
        <property type="entry name" value="Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00489">
        <property type="entry name" value="FRIZZLED"/>
    </dbReference>
    <dbReference type="SMART" id="SM00063">
        <property type="entry name" value="FRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01330">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63501">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50038">
        <property type="entry name" value="FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="11 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0732">Signal</keyword>
    <keyword evidence="14" id="KW-0807">Transducer</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043427886" description="Frizzled-4" evidence="18">
        <location>
            <begin position="17"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="19">
        <location>
            <begin position="21"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="20">
        <location>
            <begin position="229"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="153"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="71"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="98"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="GIY28354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="556" mass="63713" checksum="36F70C77BC146EAF" modified="2024-11-27" version="1">MLFLLMLTIFSDVAYGNPDLEITRTCEPIRIKTCSNIGYNVTGMPNFVGHDIQRDADLQLQTFTPLIQYGCSSRLRFFLCSVYAPMCTEKVPQPIGPCRPLCESVQGLCEPVLLEFGFKWPSALNCSQFPPVNNEMHMCMEGPQHEDQKHIPFRDRRPQRTGIQRGSGNSVSRPRYHHPNTVSPSRTISRSKCKHLRLPDRYFYINTTKRCAPACRADVLYSKENKQFAEVWIAVWSCLCFVSTVFTIGKSFFKNENFRYPEKIIIMLSWCYFIYSIAFFMRLIGGREDMACHWNPHYDEPLLIQGGLDNINCTVIFTLLYFFGMASFIWWVILTLNWFLTAGLGWNSEYLEGFGSYFHVVAWLLPALKTIAILVLQVVDADELTGICYVGNQDSQSLVRFVIIPSITYFSVGMIFLLAGLVAIIRNKKYRSKIGNRDDKWEMLMFRIGIFAILYTAPSISVIGANIYEFIAREAWLATNSTVRPNVEIFTLKIFMSLVVGITTGVWLYTSNTPQFTRVNLNLSSKLCPQQRGVPLYNPQNHVLLLNGLRHKMTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S4G2</accession>
    <name>A0AAV4S4G2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Low-density lipoprotein receptor-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Lrp2_3</name>
        <name evidence="9" type="ORF">CEXT_308361</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008819">
        <property type="protein sequence ID" value="GIY27461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S4G2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015889">
        <property type="term" value="P:cobalamin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002157">
        <property type="entry name" value="Cbl-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051588">
        <property type="entry name" value="Cobalamin_Transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559:SF18">
        <property type="entry name" value="TRANSCOBALAMIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10559">
        <property type="entry name" value="TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01122">
        <property type="entry name" value="Cobalamin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043596035" evidence="8">
        <location>
            <begin position="25"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="525"/>
            <end position="526"/>
        </location>
        <ligand>
            <name>cyanocob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:17439"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="314"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602157-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602157-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY27461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="594" mass="67731" checksum="DD6F8EB6EFD0E980" modified="2024-11-27" version="1">MNRIEKIFGILLIGALISYTEVIGKCSSREFECLSGKCIQRGWFCDNGNDCGDNSDELYCNIGRRDRCPTGWKKCLNEIRCIPANWMCDNITDCQDQSDEKTCVYGECSGDFECFSGRCIKRRAFCDNDNDCGDNSDERYCNVDLRDRCPTGWKKCQNEIQCIPAHWMCDNITDCQDQSDEKNCGNEVLRIPGVVTARLALIRWFLQKRLNSTTSKWGPQLNRIAVALHLAEDGVFALESNIRQEMTYELTIKLLNKLNNERLNAEELALYIHALLVTCVDVRDFYGRDLVEELRAKVEETRNYTNPFLMLVLCNAGDAMTVKDVEKVVAAFNSPKKIPWTDVQALATMALACLSSRQNVPVDEGVLEDMLGQLKRQQFSNGSLNNFRTTALVVQALLIHHSYKTNFDLTSAIRILINSQEMESSLLNAYYVLPILNNKSLLNVTSAHCPRETKTEEEMLQNLLEKNGEEVEVQYTIWIGNNVNLAKIWRVKIPANLTVYDVIETIAGIDNRQRAEYSVVDGKPYITAMNGMENDPEMNNYWFPYLRLLNSDEKPRVIKESPVDVRVQKNQEIILWYKPGPWSNQSIASALPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFQ6</accession>
    <name>A0AAV4SFQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_269421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009356">
        <property type="protein sequence ID" value="GIY31302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12459" checksum="E8642F4D6B34400C" modified="2024-11-27" version="1">MYEVLFQYTTRGGHKFSRKETKKGKRKKEKKLFVYVHVHVKVSYSGHQTLTTTYDPGIYRRSFNSFGVNSISAVACQIARNHCQPKPYEWTVKNWSMACRSWRYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SN41</accession>
    <name>A0AAV4SN41_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_794231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009969">
        <property type="protein sequence ID" value="GIY35858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SN41"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13680" checksum="BF0F4036AAC170E8" modified="2024-11-27" version="1">MSTLRNAIKYYSKRAFSECQFHNSFFVLSNAERNRSSVTSSSAIRRGRKRKIFDSGGISQCQSLNNSSFALLNGERSRSSVTSPRPSDERGRSLIRAELLKLDCEMEIDGMNLRLHLNGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSL0</accession>
    <name>A0AAV4SSL0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_731521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010028">
        <property type="protein sequence ID" value="GIY36301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="962"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="992"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1672" mass="183678" checksum="503B140C19ADECB1" modified="2024-11-27" version="1">MDNSSFPAKESTENNALEMSKFRDVSSSTQTPHESDYDIKRITSTKAPVSDQEITTMEEPIFTDSDETSTSGGGLLIFPETSKPSIETTENEESHLDEEVSELPESGIDSLVHGRKKNETSGFEDVTTQPDDLTTESHVESFDFSSKTPEPQDTSNKPQEITTHSSETDVKFQESTSSEASFVTKVHETQDDDLQTDGDQITNINISKNESFDSVKEEDDSHQGSSGTSVSQERISTLPDVTGNLDGSHETTTQYPKTDDKIQENVTPIIHFVTETHQTTETTEDDLHSVGDQIISVNISKDEGFDSAKEDYGSHNESSGAQASQEGTSTFQDVSQTTTEGTFESDDYKKKDDYGTEKSKTSFATSSSPDFTTSKSEQTYIPTTTKESSSGSSVASIELDGTTTEILDSDVSHSFDSGAKISDITAAEYGGFHGINKLYHFPQLKPVSTTEVPNSDIIHEEKDINVLLVKPESPELTVDTASPDEDKHDQTELPSSDVYSTLSETSHEEVRTTRVPEISSSTDITSSEKAEISTIEEKSSTTVAKDVTQETTDETIDLRNTGYHSEKFDEFFPSTTASPHDIQTTRVSETPVSTLNSSSTDITSSEKVTSEEKSSTTVDKEISQETTDETSDLMSTEYHSEKYDKLSLSTTSPQDIQTVRVSDIAESDDITFPEKVEISTTEEKSSTTVVDKETSQETTDKTTDLTNTGHHSEKFDEFSPSTPTSPHDIQTTRVTEIPVLTDVTSSGKVEISTSEEKSSTTVVDKETSQETTDKTIDLMTTGYHSEKFDEFSPSTTTSPHGIPITRVPEVSFSTGITFSEKAEISTSEEKSSTTVDKDISQETTDETIDLRSTGYHSEENNELFSSTTASPHEVRTTRVPEISSSTDITSSEKAEISTSEEKSSTTVAKDITQETTDETIDLRSTGYHSEENNELFSSTTASPHEVRTTRVPEISSSTDITSSEKAEISTSEEKSSTTVAKDITQGTTDETIDLRSTEYHSEENNELFSSTTTSPHDTQSSELLVSTDATSSEETEIPADKEPTHSGEATSQGTTDETTHLTEAEYQSEKYDVSFISTTASPRESISTTSSVKDDSFSSSVPEDSKHESDGSSDEDLTGDSEDEESIQQFTDPPKQTEKPESHIKLQETHGTSVSAKDEVSAPTTHETSSYTKADVSISTMPAETDLTSTKKKNEYTTDFVEQTDETENLFEDKEQYPSSSSIFNEDKLKTTTFTVPSTSFKSISEGNEEKEQGDSQHDLKITEIFDYVSTSKPTTIIEDSKPTTIIKDSKPTTITEDSKPTTIIEDSKPTSVIEDSKPTTIIEDSKHTTITEDSKPTTIIEDSKPTSVIGDSKLTTITKDSKPTTIIEDSKPASVIEDSKPATIIGDSKPTTIIEDSKPTTSSHLPNTVNSTFTESYAASSVPAEKKTTSLSNDINAIGSITQSDKRRPLPTFSTESISDSLITDNTSTYDSDLEVVTEHTTLSHLPKKTEVHFTTDKIQDFKSTLATSFNDKQDITLPQNLPIETSHIIDEIITQDYGFHKQTYPPKEIEESFAETTEESEFSDMHESENNNIHITEHSVKSSLSTVTTTPPSLISENLDISTISTSFEDKITVTEDTKISSTSYETSTPEKQKSKLFLHKIMVFIKKYTILQNMQKVQNLNQLKASQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7N5</accession>
    <name>A0AAV4T7N5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase aspartic putative domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_264761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010747">
        <property type="protein sequence ID" value="GIY41729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043752791" description="Peptidase aspartic putative domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="31593" checksum="34E7D805D82BD1D9" modified="2024-11-27" version="1">MSTPSCMREVLLMTLMVEVVSGNMTKRVRCLLDCGSQRSYILRSTAEALHLKSFSSEKLTHSLFGGARTESKNHKRYSMRLRPVGRSTGYQFDFLDQDIICGVIPRIPKGPLLKELKGHRIWISDMGDDYPEIELLIGSDIYGQILTGEVIQLNEGLTAINTKLGWTLCGEPKELNVQNLEGAQSMLITNLHVQNMKASDMWDLERIGITDEVQTFSKAVEDQLVQEQFLKGLSRYEDGRYCVSLPWVLKFPPNIASNRHIAEKKAICHYTEIKEIGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TCF3</accession>
    <name>A0AAV4TCF3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal transducer and transcription activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">STAT5B</name>
        <name evidence="16" type="ORF">CEXT_389181</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="12">Forms a homodimer or a heterodimer with a related family member.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transcription factor STAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010902">
        <property type="protein sequence ID" value="GIY42864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TCF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09919">
        <property type="entry name" value="SH2_STAT_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.630:FF:000003">
        <property type="entry name" value="Signal transducer and transcription activator 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.20">
        <property type="entry name" value="STAT transcription factor, all-alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.630">
        <property type="entry name" value="STAT transcription factor, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001217">
        <property type="entry name" value="STAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048988">
        <property type="entry name" value="STAT_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013800">
        <property type="entry name" value="STAT_TF_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015988">
        <property type="entry name" value="STAT_TF_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013801">
        <property type="entry name" value="STAT_TF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012345">
        <property type="entry name" value="STAT_TF_DNA-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11801">
        <property type="entry name" value="SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01017">
        <property type="entry name" value="STAT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02864">
        <property type="entry name" value="STAT_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21354">
        <property type="entry name" value="STAT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47655">
        <property type="entry name" value="STAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SH2" evidence="15">
        <location>
            <begin position="387"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00064301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00067653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY42864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="528" mass="60587" checksum="0D293ED6BA449FBF" modified="2024-11-27" version="1">MACAQQNNYLQDVSTEMDFPPDPVQEINAELIKLRHKTQESDEGLKKLKHCREIFVIQYQKSSTCEVQTEQNSDQGGKLIYDFRQLLKLRMELYNNFLDIYFQLEKLQKKFLNTHLIKWKRAQQLYGNGVPFQNNLDKLQEWCEMLADNIWHIKLNIGRIEDIFACFSNPEINFKNLPILKNSFIVLLSSLITNVFVIEKQPPQVIKTNTRFSTKVRLLVGSKLGVSMSSPQVKVTIVSEAQALELIRTGKNGIEASGVILNNMGTMEYHEATGQLSISFQNLQLQTINRAQKKGLDSVMDEKFSLLFQTQFQVGGGDLNFQVWTLSLPVVVIVHGNQDPYALATITWDNAFGKPVTSGFVNPEAQVTLSQFCKESLPKRKFTFWEWFYGIMKVTREHLSYLWNEGHVMGFVDRQHAEELLLQKCNGTFLLRFSDSVIGGVTIAWVADSQARGSREVFMVESITSRDFLIRSISDRIYDFEILQYLYPALPKDQAFKKYYTLNTGEINPNGYINRGLISQLPGFVAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TMV1</accession>
    <name>A0AAV4TMV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_439361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011418">
        <property type="protein sequence ID" value="GIY46441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TMV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="16898" checksum="484D86592AC1391C" modified="2024-11-27" version="1">MTSMKEENQYDNRRRGLHHARKTSNKKGLHHCNPNPAPVNINTNRFSIPTNSHPEVADEGNREQFARRPRIPPFFVKTRPDCHSMLTLIRQEAPSLTAVMSRDHFFKITVQTDQEHMKLKHFLIDQGFDFKCFSLKSEKPIKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS47</accession>
    <name>A0AAV4TS47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_259431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011737">
        <property type="protein sequence ID" value="GIY48629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12024" checksum="C52257A88C67038D" modified="2024-11-27" version="1">MQLDCVAICRDLPAIRPLGTICVCESWFPAHLLRSQVFGSALYPQSSVDLQPLWTEKAIRAPSTASPANNKWFNKIKIIELLYKYENNNSLLSSIEFFNVSKYSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUI5</accession>
    <name>A0AAV4TUI5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SOCS box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_26769_1</name>
        <name evidence="1" type="ORF">CEXT_283681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011914">
        <property type="protein sequence ID" value="GIY49930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUI5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12145" checksum="89A97E332A248DF6" modified="2024-11-27" version="1">MTLMMSDDVIDDVSGLETFKKLCFPIHPLFLSAAELLCWFFESERYWNIENPQRRTQHTYFIDKLALFCRNFKVLLLSTYNPHDIENNVAYILMKYSKVQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWF2</accession>
    <name>A0AAV4TWF2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_785811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011823">
        <property type="protein sequence ID" value="GIY49352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY49352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8703" checksum="430B5ED1E8819EE8" modified="2024-11-27" version="1">MSHKFDFIKLLCLQCRRRFFSAGGLETHMRSMHGVRIDSANCVPSFKEPSRLAVDPPTELLELGPSTGRSTAYKFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYU8</accession>
    <name>A0AAV4TYU8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_809131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012052">
        <property type="protein sequence ID" value="GIY50961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12458" checksum="0B1E15D91CDB88CB" modified="2024-11-27" version="1">MVKFVSLQSAARCHDTPSTIRLQGDFAGRLPGNAGLSHALPFVPLLQNGSTHHQTRHCSRKLWSGGGTLFVNFCTFLCLALIVFQKFGAGVVGLLFVVDCSLNCLNGNIVDKRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U275</accession>
    <name>A0AAV4U275_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_136431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012174">
        <property type="protein sequence ID" value="GIY51899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U275"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY51899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13486" checksum="D05E512D0A987A87" modified="2024-11-27" version="1">MQNTTSQEVFKVLTVLNDAYATPRGLDLLNILKSHELLSIVCNIPFFREELGLIGSIMIRLVAFMLIPDPSHEMQACQLSIRNLNEYSQYDAISFNKRNSRGRPRGWRMMNTMHEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U692</accession>
    <name>A0AAV4U692_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_232261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012347">
        <property type="protein sequence ID" value="GIY53301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U692"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9823" checksum="61C67E0D8F359B1C" modified="2024-11-27" version="1">MYAYTSIVLYFDDSLSIVQNLLYVYLKKSRDFRKRLFEHIAFQKAFEHLKLQNIRNYSAQQLKTIINKIQNTLSHKKPNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8J9</accession>
    <name>A0AAV4U8J9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Octapeptide-repeat protein T2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_312721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
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        </source>
    </evidence>
    <sequence length="2163" mass="242512" checksum="E0AADACD2F957DD6" modified="2024-11-27" version="1">MRNNQENQKQIKNASPNAVVEQTPLFKNDSVPSNVKKTYPIDSVPQSFAGTNTSESSAQKKEAARLQFDSGNKQCLNSEKESTEPLMKENLIEKSSRQLDTRNLYKGFSNEGHSTNNGVSHIKLTNEITNNTDSVKEGFTEVTRKDIKATKDKESSIDVKDQSIQNMNSYQQIGNSEDSGSAKHNNQVRNNFPNSFYQLSYFQPQDRNFGTPSKLLNENYMGEKSMLKIVGDFFKNNEKFKFIANNQKIHATNNEPTKEVTEPTALTENERDKRHEKIVNRSDKRSAAEKEDAVHSENQSTANPSFNYDFSGNKYKEKAISSEISSLTSYLENMSIGSVEKHKTSKNTDKTKTNIFASNCSYLQKYGSENIECSNPLTSTNIFKESREGNNIVETLSNCCEQEGDIFNATSKALAKTSLISKHALSKDKRNQKMRKLIESKSQGRKILKAKLNKKADKMHDEQNDKEESSFPTNVPVTQAFAEEKAMINMERKNPTKINDTSTNFVLNSMPTNVPQYIFSSEKLKYTPNANVYFTVGKKDANTYESRKTENQDNVRINYSMQNEKTNTLQKEELLNQDKNIHGQQEFSKVINAYLSKLEEEKDSINSNLQETHVTSNEKSQPPYMQSSAVNNADERTESKDETREVKPKVLDTQSNTSGKTNGQKEEKKKDTKKKSKPQMQHAQSIAVNNTDERTESKDETRGAKPKVLDTQSSASGKTSGQKEEKKKDTKKKSKPQMQHAQSTAVENTDERTESKDETRGAKPKVLDTQSSASGKTSGQKEEKKKDTKKKSKPQMQHTQSSAVENTDEQTESKDETRGAKPKVLDTQSSASGKTSGQKEGKKKDTKKKSKPQMQHTQSSAVDNTDEQTEPKDGTREAKPKVLDTQSSASGKTNGQKEEKKKDTKNKSKPQMQHTQSSAVENTDERTESKDETRGAKPKVQSSAYGKTNGQNVVKDENGQIKQSASNVHSGTDNYPRGQHTKEGEALKPEQPIMNLKLNSSEDNNATEGKKLKNKTSETEKKVSNRESSANDNELDKEKKKDKKKKSKPQISNTQSSAEDKHSEKYEGKDKISKSPQKVQDKQSNADTNAHEKNEQEDATSNAQQLSRDNQSNGGCNTVEEIMKKDKNSESELVSNIVPIVDNDLSEQNKEKNEINKTGPQVLNKQSNADTNAREENGGEDATNKSQQQIPNNKSNTANNEENRTTIMDSSAHGIINSQQKQRKTYAEACKMSTTKHETLSENTKHEINENKQKDRAILIHDSSSGSSNRERSADSKPSMTLDDNSQNTEESGRTSNTKESTAKENKQPVCKPLKKEMIPKACTTLDIQSSTSEITIDEAEKKDTNHLDPSTQEGLSANSHDLQSSTSEITTDETEKMDTNHLDPSTQEGLSANSHDLQSSTSEITTGVTEKKDTNHLDPSKQEALPANSHDLQCSTSEITTDETEKKDTNSHDLQNSASEITTDETEKKGTNHLDPSTQEALPANSHDLQSSTSEITTDETEKKDTNSHDLQNSASEITTCETEKKDTNHLDHLTQEESSANSPPESEILEDPDKKLNKENETATIANSQITEETRSFKNVIESSTNENLEQTEKTLAKSDNASDIGNNNSSNASGESEVKDIIHSDGSDYRFDRQQQREKQKKVAHKEGEAVSCANSLIASTHEKNLKDENTLQNYENAKDLESDSDKEVFEDANEDIQDSLKKFVMQSGIDESMDDGFSHQLTSSCHENSIINQETQQDFEILLDNCPNVGSEPPLSEEQAICIGMEIIDSQSENWDNSSASTDYDADHSSRFISSDSFLSTKQHSFSENVAMDEKSITKSHKQKRRSYPRRKHSFSSEDDFLPQGVCWDDNLCQPVSEENNFSNVEYMDVDHDGEKPVSEQLEIDNRVEDGKYATAESSEKQKEQALEYMDTGKDMASKILPADASENGETSNKAEPIPSQESENYQRNHKTPICRLECEDMRIKLFDPTSEINVQLTYKNKNKQKFSRKVGKRGGRRANENANSENDSAEGYQTVENSESETSTSDNRNMSSKCSSEPSNTNSRTITSGQSAEDSETASQATTSNHFQVGSKRGSELPVVDNLDMNDTNQAQFGHLTKRIRLENDEPFYFINDSIELNLKPGNRRKCIKFKYNQIRRELNLRYKNMHLRISEKFEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNP0</accession>
    <name>A0AAV4UNP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_488861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013208">
        <property type="protein sequence ID" value="GIY59466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="16734" checksum="BDC289C5740F6606" modified="2024-11-27" version="1">MGQVQTVIPQIPEVKLPICVIANNLTVLKVLNKMKIDVGDYYMEPPEELQSTISKEDGYTDFTAKQIDEISANFIYSSFFSSGPGKKESLQPYGVEVCRFLYRISNVQHCKSFVFFMHMASCEEFNKDILSNVLKLLEDWSFGPLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UUV8</accession>
    <name>A0AAV4UUV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_335541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013501">
        <property type="protein sequence ID" value="GIY61686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UUV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY61686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12457" checksum="E3CDF41830DD2305" modified="2024-11-27" version="1">MKINQQRSSTSPFGLLFICHESKNGAKQRKAKKCKPNFLSSRVCFQKEVDCNFVPQTPCNEEISLFFFLLLQYKEKRSNQNGKRKKWEKCNFRVKEFLENPRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBN6</accession>
    <name>A0AAV4VBN6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon 297</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pol</name>
        <name evidence="2" type="ORF">CEXT_513251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014223">
        <property type="protein sequence ID" value="GIY67289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053134">
        <property type="entry name" value="RNA-dir_DNA_polymerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559:SF435">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559">
        <property type="entry name" value="TRANSPOSON TY3-I GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="247"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY67289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="422" mass="47413" checksum="E2D675057DCD54D0" modified="2024-11-27" version="1">MHSGCVINSKILIDKFEYADDFVVPHSNLSPVFDIILGLNFLNKNEFIIDCKNNSLRNESTSINWNFETSFYNVFGHIDGKINKKFKEKLDTSLQNEIYRSQMKLIGKSISKVRIPPNSQRYVDISIQPTNVTLQVGQPLLIEKYVNSHSSSLLVARAVSNMNTYNKCLALILNLNDSTLVLNKGMALVSIEQVVSIEQVAELSDLGECSIIKHEIHLTDNIPTRQKPYRVPYNLKSEMKKQINILLDAGIIQPSTSSYAAPVLLVKKSDGSFRLVADLRKLNSKTIPDNFPLPNLNEMTDMLSGCKFFSTLDLTSGFHQMQMNPSHAHLTGITTEFGLFQYKRLTFGLKNAGASFQRLMSIVLAGLSDLKIACYIDDIIIASKTFEEHMNRLEIVFKRLQPANLKVKSQANVPSCSTKSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDY2</accession>
    <name>A0AAV4VDY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RDR1_7</name>
        <name evidence="1" type="ORF">CEXT_483261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014331">
        <property type="protein sequence ID" value="GIY68116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13002" checksum="101795DEBE43BAC8" modified="2024-11-27" version="1">MPERSNSFSTSHKSHCGNAKASEFAFGTIPDMKHFVQCYAFQQRGSTSSILCSFSHLQRHFIVYVSNTHRSSCIHTGEMGHKMKINYDSLIRIVANVDTSKTAAELFTCTWNIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFX7</accession>
    <name>A0AAV4VFX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_722651</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014502">
        <property type="protein sequence ID" value="GIY69190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050328">
        <property type="entry name" value="Dev_Immune_Receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373:SF387">
        <property type="entry name" value="LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN SMA-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373">
        <property type="entry name" value="SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY69190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="291" mass="32908" checksum="9A65DDBF00DBE7EB" modified="2024-11-27" version="1">MLAALDLSFNLIEKVANQSINFGYNIELYFNNNKITEFRDNLLFVQRVHLDQNLITTLGSTLHYSKVTQFSMANNLISHLGPEDFQNVQGLQELDLQGNLITQVERLTFVSIRKDLSYLNLSRNKIKCLQGCLQNLTMLTTLNLSCNRIEVFKPGDFYNMSGLITLYLDSNRIATLGSELRPLTSLQYLLIGNNQIRTITTNQIPAKLKQLHLAGISLHTTVPGILKKKDTPTTQLKTETLAMIAERYPSEEWFHVYKSRSQKSEACCAGFFSTVAKGSIAVGKFARKFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VPQ8</accession>
    <name>A0AAV4VPQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Patj homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Patj</name>
        <name evidence="2" type="ORF">CEXT_347281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014871">
        <property type="protein sequence ID" value="GIY71934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VPQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051342">
        <property type="entry name" value="PDZ_scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19964">
        <property type="entry name" value="MULTIPLE PDZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19964:SF92">
        <property type="entry name" value="PATJ HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="142" mass="15353" checksum="8780E744CAED2F16" modified="2024-11-27" version="1">MCVCSQDGRLQSGDHILQIGEVNLRGMGSEQVAMVLRQSGSHVRLVVARPVDSSSSAPAPAGRAALVPTRILADPEEVERHLAMFEHAAAEPDPYKGPAAHDDTTFVYRREIDPQVSPPSPTSYLLFAGRSINRESAVYGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VUX7</accession>
    <name>A0AAV4VUX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_402781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015166">
        <property type="protein sequence ID" value="GIY74082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VUX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14635" checksum="3F59333470F30ECA" modified="2024-11-27" version="1" fragment="single">FYHGQFDDCDNTVETEMLPKYDLLQQSVEIHTEGTANHQIRLPSIRYETLTNKNCISKSSKQCRIQDVNQIHANVCCSAKNYPVVESEKMKNSPKGIHLYNASTNYKESPSHRQETTQKLGKIYQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VVF0</accession>
    <name>A0AAV4VVF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_40399_1</name>
        <name evidence="2" type="ORF">CEXT_701411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015081">
        <property type="protein sequence ID" value="GIY73458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VVF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="196" mass="21641" checksum="5371E69DAE35932E" modified="2024-11-27" version="1">MTLLEASTPQPSQRTTYGGGLKPITGSSKPQLLSVAPDTYRQAVSMDCPRSNRYDEENKESYNAVSVPNAPLQALDKSRNQALPLQTSCTTSSSGSMSVDIYLPQGAVTIKIHDDMKDHKKSPIKPADSEESHYVKFSEQSDIQSFDNDDLFLSTELDDSVFLNQESNISTPQIVLEKMDPVKRNEVIPLINMASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZP3</accession>
    <name>A0AAV4VZP3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_807611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015296">
        <property type="protein sequence ID" value="GIY75064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZP3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="311" mass="35478" checksum="EE43EFA576A8B60E" modified="2024-11-27" version="1">MQADLNCNKLKKSKQISANVTRNAESSSQKHSTVFLPEERSGKTTNVKQRRGGKKRRCNPKSNALQNSKNKNASIWKVKNKTNATCDKDDKLVPALILQRPSRIVATKSSSPTNASEKLFLQKMKTFFLKDQFSPSFQSHQFTNTVEENKVGRSKCRSLIFTPPIMNDVRRVFGVLRPRYRSAPPFRNNNEIQFQSHVSNKMSNEIINFDVPPAASSSNISDWKFGNWDFDTETVYSNNESTCYNTETSCTEDTSACEEQAKIKLKKHNVVVQSRVSAERKAKTKARLLLKEILPKRRERICKQVLETNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W652</accession>
    <name>A0AAV4W652_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_539691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015575">
        <property type="protein sequence ID" value="GIY77073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W652"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13182" checksum="23F4C40F1391E2C9" modified="2024-11-27" version="1">MGTIVHQRFVSVGKFSRVQVEQWRVVTCMCNQPIGDFTLCGGGEFSAGVEIGSGIGDTDGGEGCELLVGAGGHLPCNILRCRPEVVVMGSFDTNCVCTLFEEELFGKLDFLAAHHEVASGTVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W780</accession>
    <name>A0AAV4W780_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_444571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015678">
        <property type="protein sequence ID" value="GIY77774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W780"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9427" checksum="D1ACAFC942B80BA3" modified="2024-11-27" version="1">MGGRKGRMDGRRGRKEGRGGRKEGRKEGREEGRREEGWMAGWMDGWKEGRMDGRKDGWRKGRKDGWKEERKEGRMNGMNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WB26</accession>
    <name>A0AAV4WB26_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_395201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015866">
        <property type="protein sequence ID" value="GIY79280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WB26"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY79280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9298" checksum="5A8E6619EF0CCEF7" modified="2024-11-27" version="1">MREQWDRQAITTQSNASPLSGCFSTPPFISLPSAAFNRLPSKRIASTSPLRIAPSGVPSPPLSPPLPRTPAPGRKIYRRSKKNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEF0</accession>
    <name>A0AAV4WEF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_421331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016002">
        <property type="protein sequence ID" value="GIY80356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12416" checksum="D310AA63302CC734" modified="2024-11-27" version="1">MTIAKWELNYRQVSTKREEQSQKGLQESDSLSILGCIFNIGEASQSLVDAYEKGQKKTVKRQRDEKVRGDKRNRDNCLKEIQKFPDEEDLNIRIRILSSPIERGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1R6</accession>
    <name>A0AAV4X1R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_134611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017008">
        <property type="protein sequence ID" value="GIY88006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349282" evidence="1">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8829" checksum="AC0DA11291234AEA" modified="2024-11-27" version="1">MLFTLILLNLNMKQSQTVNMKARKNPSHLTASDVNFPQDSLVKSGYKPPPIPIMFPRAQQLARLSVILPTPSHSLPVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X2C5</accession>
    <name>A0AAV4X2C5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_577671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017053">
        <property type="protein sequence ID" value="GIY88340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X2C5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="350" mass="40003" checksum="A57C77E9FACADF3C" modified="2024-11-27" version="1">MNSDEAVKSNENLDEKVENNSEIFLNHQIGKKNGTILNCCVKKIKKKYASLSMVKKTRRHKRHKMHTIRNKMFQSLSNTISSKSINDNDTVLPFPTTDFDVIDYSPKPGKYAAVENIPLSNNSAAKSFPILSPINVEKSVKIDKQIKKHSDEFFNIIESDNESSLNSDKGKSENTYEVLDCMEKKIKKKSQKYDADMACNSPFQNLHEISAGEKNKESDTILSFTTTNSHGNQYSPKPEKYAAVEKVSFSNNGAAKNIPISNPSDAEKFEKMDDNIKEKLEECLNMIESDNESTLNSDKEKIKNKDEALEYMEKKKKKKKESQKYETDMACNSHFQNLHQMSAREKIKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7I5</accession>
    <name>A0AAV4X7I5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_157911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017381">
        <property type="protein sequence ID" value="GIY91090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7I5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13623" checksum="FF376BCE64B9C71B" modified="2024-11-27" version="1" fragment="single">MKQIHQISTSQIKTSLLTYNDIGTGCISHELFPFKSIFRLRNICASKLILKNCLPFLFIGKIHPIAEAKKRGAANRAPQLKNEPERQIQSRKMEMGEREEKVLPHSWFAPSADGGGEGAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8F9</accession>
    <name>A0AAV4X8F9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_232431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017308">
        <property type="protein sequence ID" value="GIY90255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8F9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9513" checksum="CEA3CFE07DE2D5B8" modified="2024-11-27" version="1">MVEKDSIDDSDENNNMVPKELIQHTVAVPNEQIGCERRLLVPFGVPEKPTKKSQICPFFIQPMPVPITYPSPNAPDDQFIHRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAI1</accession>
    <name>A0AAV4XAI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_18091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000094">
        <property type="protein sequence ID" value="GIY92095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="20" mass="2221" checksum="85C79FF1A84A6E74" modified="2024-11-27" version="1" fragment="single">MWEEDAIGGASASKESMRCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEP9</accession>
    <name>A0AAV4XEP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_391591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017693">
        <property type="protein sequence ID" value="GIY93697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9027" checksum="E0A26E1A5E161795" modified="2024-11-27" version="1">MPPPPQAKKTDRGCEKISKKRNPNESCHRLKVPFFSVSACLVFILRSIREQSLPGAVSSAVFRFYRFLSIPVGREMCRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJB1</accession>
    <name>A0AAV4XJB1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_27901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000422">
        <property type="protein sequence ID" value="GIY94742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJB1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18847" checksum="46D1C8DAEC489B3B" modified="2024-11-27" version="1">MPLSICPLKCFPSKRVLGSEEAPTALSPSRKTTFLPPKPIPSRITNRERNQQVDVQRRHKSDRTERDLCNHFSTACSKDGVRNGPIFSWSISWEVKRNGLHSEEVYLMYNAASRMMGLKHFVPFACWRGYVTELIKNSLSSNRRDSYLPARRRRKTSQSGKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKD8</accession>
    <name>A0AAV4XKD8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Vps45</name>
        <name evidence="7" type="ORF">CEXT_424541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017833">
        <property type="protein sequence ID" value="GIY94868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKD8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.830.10:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2060:FF:000003">
        <property type="entry name" value="vacuolar protein sorting-associated protein 45 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY94868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="593" mass="67623" checksum="05035ED7306CEA59" modified="2024-11-27" version="1">MNAATAVKLYVNKMIDDCGSGMKVLLMDKETTSIVSMAFAQSEILQKEVFLFERLDMARSEPMKHLKCITFIRPTKENIDNLACELKYPRYGQYYIYFSNIISKSDIKILAEADETESVREVQEFYGDFIPVAPHLFSLNISPCYQSRSWNHNHLTRSVQGVISVLLALKKIPVIRYQDTSECARKMAEIVKQTIAKENALFDFRRPDIPPLLLILDRKIDIVTPLLNQWTYQAMVHELLTINNNRVNLSNVPGISKELAEVVLSPDHDEFYAANMYSNFGEIGVKIKELMDEFQKKTKSQKKVESIADMKAFVETYPQFKKMSGTVAKHVTLVGELSRLVGSHNLLEVSEAEQELACESDHSESLKKIRKLLGNDKVRDIDAVRLVMLYSLHYERNSNNDINGLIDLLKKRNMSDKLVRMVKAVLEFSGNKGGRSDLFTTENVRAFTKRVIKGLKGVENIYTQHTPLLKEILEDIIKGKLKETSYPYLSGTQLRERPQDIIVFYVGGATYEESLTVHQLNRQSLGVRILLGGTTIHNFTSFLNEIKSGDSNASFRDDCMEMDELSRCKNKVITLGYLNPNLLIFAPSSLLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKF0</accession>
    <name>A0AAV4XKF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_284221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000559">
        <property type="protein sequence ID" value="GIY95661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9372" checksum="CCE0D9B9B415F838" modified="2024-11-27" version="1">MKSRRGNTRSSRRMLSISNERVNRILKELLRMKRALFITGMEWDEQIPTFLRKETEDRQIFDFAGKSETRAAKDVGPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKR2</accession>
    <name>A0AAV4XKR2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_232934_1</name>
        <name evidence="3" type="ORF">CEXT_338341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000401">
        <property type="protein sequence ID" value="GIY94530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY94530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21094" checksum="28EF69200D9AC3A1" modified="2024-11-27" version="1">MGDTSTMHDIEEYMASFSNTNGNSTNSLINLDSSSDEVEIIQELKINLDNHQCDLCCKGTFLVNKLLQFGGVLNDKLKHACDICNQGFKTKSSLTKHKKLHAQGVINENSDIEIELEIPTKKTSVKVNGLSESVMCKDYDMIYGILLHFSQYSGEPPYNIDLCQVVSNFDEFFEPSITESCNEAVYAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKU0</accession>
    <name>A0AAV4XKU0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_48231</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000573">
        <property type="protein sequence ID" value="GIY95767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF13">
        <property type="entry name" value="HEAT SHOCK PROTEIN 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="37"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY95767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14503" checksum="57D1F89FDBE9E744" modified="2024-11-27" version="1">MNIKYGPYETLRNLPEWKFGDSSCLSNNPPSNFRDDLESASNAAKNRTSKKSKTALVKLDVKDFSPDEIKAWIDGKSLVIQCKHEEHDAGQKLVLEEMNHRYQLPDDVEETPKLSLSKGVLTISAPGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XL98</accession>
    <name>A0AAV4XL98_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_73054_1</name>
        <name evidence="1" type="ORF">CEXT_638701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017817">
        <property type="protein sequence ID" value="GIY94711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XL98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="46041" checksum="C681064F2FE4C883" modified="2024-11-27" version="1">MSIELQKDNQNAKNLKVSLLTRIMSKYGNNLDSNFLPIAINHLTVIDKYLEDFFAKGREAFPNRQEYQKFAIAKLFIDKLNLIDFEPDPLVEEYGKCIGKYPPIEAFHLTNELKEIKRMNFCRNVDKGDVLHVRVADESESEYRLIVINKYNERERLLDYSICAYLLKSHHLDKLPSPLKKDDLLRVTVFGRLKIEDNVFSKLLVSLNQSILAVKFKDIHLGLIKQEEINFYPEDLSEYKTFYDYLKAHKSAENHEELTNLSVSLGMDPYKMYSFSEAYDGLSPTYSSTSETKSKKHLLIQKSKELSENAQKLSLETDIYTVLYLLNESIKIYDKNDVAYALRGKTYFCLWIHSKMPNRYMSKAIEDLRIALKINPFNKMAHTELSEIKSISSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XNQ6</accession>
    <name>A0AAV4XNQ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclear receptor coactivator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Ncoa2_1</name>
        <name evidence="1" type="ORF">CEXT_49251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000645">
        <property type="protein sequence ID" value="GIY96294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XNQ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY96294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12620" checksum="2C51F4996D1B2167" modified="2024-11-27" version="1">MGGLLGDGQNSASNATQKFATFSPTGLRRLIHLFLKTHLLITWKIWQEVPRTVFVNHNSGESMPSQNIILRELLNQEDDDMNDEGSKSLSCDSNCNVSMVSELCSYDNMQKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQ61</accession>
    <name>A0AAV4XQ61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_403361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000767">
        <property type="protein sequence ID" value="GIY97311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQ61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10310" checksum="5976CE349CA3B312" modified="2024-11-27" version="1">MPDPKPTPDQMCLFLYLVGHGTTVKSAPHKDKRTHLSKTMSVTWSKTSLTMTGRSTLSGLRGKTADTCRLDLPVNCERFKTPAPNPVRQQGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT24</accession>
    <name>A0AAV4XT24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_397691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018123">
        <property type="protein sequence ID" value="GIY97141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY97141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12030" checksum="C49A8253886428A8" modified="2024-11-27" version="1">MGFHGKDNRSVLNSSEYDENIRHSQASDLLALCLVVRTFVIVIAKVVVAFRASVSKLMIADSIQRKTTFAKRSTTRKAKPSGRDRSHVEVQTMKTTTKEVDYIIENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUB5</accession>
    <name>A0AAV4XUB5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_62361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000832">
        <property type="protein sequence ID" value="GIY97760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY97760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11680" checksum="C2D4AF58FA2BB79C" modified="2024-11-27" version="1">MMFGNICMIIGMFITVLFTWCFSPQVSMMISAMPAVAVRRGRKKRSKNFRPLQLTSESPLEYFTQRTQPKLRQTPGRAEHQHHQYPVWGQQGLSTPGPIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUE9</accession>
    <name>A0AAV4XUE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphatidylserine decarboxylase proenzyme, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PISD</name>
        <name evidence="1" type="ORF">CEXT_59741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000918">
        <property type="protein sequence ID" value="GIY98357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="146" mass="16841" checksum="458EDC74CCDAB562" modified="2024-11-27" version="1">MGGRGYALRFNQVCLSLSKRINYHNIMFTIFSSPSLQNLAMYSGKLSTNCIVSPYSEITKHLLTDSSVTCHYQNYAHKSSFSEETWHKARTNPILKYFRSLKWTPIPIGLGFAIIAYQQFRHVTKREAAKLASSKALLIYWHLIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWV1</accession>
    <name>A0AAV4XWV1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_95931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001071">
        <property type="protein sequence ID" value="GIY99625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWV1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7666" checksum="C9A39E86483D8B38" modified="2024-11-27" version="1">MATPPWRKEGKVVLKHPKGVEAPIFQSTLYYHSIENKITEKSLKKDLCFISTGQSTNKPISSVTIFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ68</accession>
    <name>A0AAV4XZ68_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001088">
        <property type="protein sequence ID" value="GIY99838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ68"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="11053" checksum="7E7EDE2BC10D6571" modified="2024-11-27" version="1">MTGNRNAIRLDRAKLFDMTMMDSPFFLARNNHQQTFTPPHQQETRSVTQCSLFRRTPKIEHLKKERLLLFIMNLPRLLPYGPDQDTTTQQHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y277</accession>
    <name>A0AAV4Y277_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL/TRIO N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_599581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018641">
        <property type="protein sequence ID" value="GIZ01248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y277"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL/TRIO N-terminal" evidence="1">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="223" mass="26644" checksum="193C8691205AB3B1" modified="2024-11-27" version="1">MVSKSTRNLYHIISFWIWFITIQKKRDRLLNIHNYHYQIGFQKAEAELHDTPDRRAQGLRQIRELAKNDKHTKNIEFDDDFLLQYLRVRKYNVARAFSQLKALVALKKRYPLMFTHFNYDKTVKTISDKFITMLPWRCQDGCAILLVELDNWIPEEFPVEEIKRAVLVYLLQSLRYPMTQINGFKAILDLKSNPLRHLKHCTPNNIYLIYHGSQVSGEFFSHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3D4</accession>
    <name>A0AAV4Y3D4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_157492_1</name>
        <name evidence="2" type="ORF">CEXT_324231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018719">
        <property type="protein sequence ID" value="GIZ01767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3D4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="57745" checksum="220F97850E90BBCE" modified="2024-11-27" version="1">MEDIPNLSSDDDDLPELFPFKPFYPENLKKNDIVWADYKDLSWPALVRNVDKKKKKVSIWFLDSPKNSFKLPFKKIHDFNNIEVSTEIHKRAAASPLKEKHSAHIKKALTFLQRKSEGIEDDPVAFFDPNVEFYFSTFEYMANNSSNSKTQSSNQIDLETDKSKSSDGESSNKNSDDESSNENTDNENSNESSDAESTLETIQSKPNKCGDYLKEERSKLKDLEGEQLKAVVSYIKAGHADQFVLDIVYGKIKTLRSIHFKEDSDPISLGMISPAMVQLPSEQMSEVTQYLVDLYTRKVKMNKEPRLMMYAAFVLLPAVVEKVLSIVEVDLSKSSNTDDVTDTPNTKSSGVEKDCKSIGSENELSTPIEAICANEAKETVSSEFSMISDSVSSACKLNIKPRGSNLCPNRSEIKPLETLNVSDIDDSPCKNCKKSCSSSLCDLENLCGSDKNEGEPSPKKTKWSCKRFAKVTKFPLKRIETESKATAEIVEEIPKVVQERDSLNIEDSMKKRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y678</accession>
    <name>A0AAV4Y678_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_684951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001484">
        <property type="protein sequence ID" value="GIZ02643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y678"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11844" checksum="4E5A15FA7EA077E8" modified="2024-11-27" version="1">MAVFCVPRQTPCLSLQNILDKEFVLRKENIPFFEQRTLTQWRRFKAAIKLLSPQNMKQFRSLARRISILQTNEKCSRFIFMFGGQSRCSVCTPFKDLYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6A1</accession>
    <name>A0AAV4Y6A1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_572661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018861">
        <property type="protein sequence ID" value="GIZ02787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6A1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="19787" checksum="68373D045241D104" modified="2024-11-27" version="1">MWRFSAWLKKSTLLKNLFKHQKRQEISQNESSEDGQVGRTNAGERSVRDAEGTLERNSPNKLQRKTSEQGESSLQHISKRCGALKESETAEKREIVRERIRARDHKSRAVETPEEREARLEKIRVLMSQIVAAETDGYRERRLESRLLQQKMDRERETPAQWMARIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YEL7</accession>
    <name>A0AAV4YEL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_140551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001738">
        <property type="protein sequence ID" value="GIZ04461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YEL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="9154" checksum="AF1FAE58EBAB63B2" modified="2024-11-27" version="1">MWRGKRGLCRATGLPKGSKQEKVLLLEDEKMCLDEVWKDKVMSVKNRRKSPQIRYLLNDFFRMIRFVSFCREQTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YEU0</accession>
    <name>A0AAV4YEU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_568511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019133">
        <property type="protein sequence ID" value="GIZ04764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YEU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11646" checksum="E1FE64228A014C53" modified="2024-11-27" version="1">MTNAILSFHQWNNPSHTEGTQKGSATLHYQKHKRSPTAEGNSFLVCSRSISVRPDMEEWLLPPPPPYPVHPTNAWAGGGGEEKSFEISPRAVAQKRKAKRRKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YF23</accession>
    <name>A0AAV4YF23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_133341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019115">
        <property type="protein sequence ID" value="GIZ04626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YF23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8334" checksum="EBAA079D52ED352A" modified="2024-11-27" version="1">MEDPVLDPFLCTSAYSLLLGLFGVGVLFSRCHFTQGCRSSWNRKVQSMEKVRLSPVLVIVNTSEAISCPLVYLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFY7</accession>
    <name>A0AAV4YFY7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_494281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019200">
        <property type="protein sequence ID" value="GIZ05077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFY7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10633" checksum="365A49E806A186A3" modified="2024-11-27" version="1">MLPKSEAVSSFRLATVLATDLLSTYLELAFLQHPATTSVIPKMKWMLSIFSSAQPYLLKVSVDDTGKWENLWANAEFFFFVFCSLCSFYFKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5B9</accession>
    <name>A0AAV4M5B9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_765171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001805">
        <property type="protein sequence ID" value="GIX66581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5B9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="11423" checksum="87B7396CB65BAF42" modified="2024-11-27" version="1">MWLHYCFSNCTEKDHLLRGTSKKDLFCDIRLLIQKEKARSISSRDNDLKPRIQMNKWFTMSPSRSESSHNLTLGSQNSRLQTRHLSLEKQESFFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6Q9</accession>
    <name>A0AAV4M6Q9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_380851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019452">
        <property type="protein sequence ID" value="GIX68048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6Q9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8721" checksum="2D1903E472333924" modified="2024-11-27" version="1">MMRRGGRDKYIVCASPPTRTIIAVVRRKSDETSQGTGAGTLLGRSGDRDGIKIAWRGKGWSGRRKQIMGVERLSRSSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6V3</accession>
    <name>A0AAV4M6V3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_657031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001916">
        <property type="protein sequence ID" value="GIX67975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6V3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14880" checksum="21AADA312E8A34DB" modified="2024-11-27" version="1">MDRTPKRTGYIKIYKCQKKSKKEEEKNRQYTDILYRATKRKAFLLGAEPQHERGIQYSVLVEKIPESQEGSPKMEKKRRDSQKPILGKENYRYFGENAHLELWQRKNLFLWGKRGSFKVKKGKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8M8</accession>
    <name>A0AAV4M8M8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_464001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019381">
        <property type="protein sequence ID" value="GIX67184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8M8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9478" checksum="B1042A3DB8A582F5" modified="2024-11-27" version="1">MNNSTPPDTLMPRDELREVTGCWDTSPQGSQVRIAGQCVLIPERGGIPLLSLCGVSAWAVPRELCSRGLTDASPVVYKCANALHANRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MA57</accession>
    <name>A0AAV4MA57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019562">
        <property type="protein sequence ID" value="GIX69249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MA57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9457" checksum="AE083B806A406A78" modified="2024-11-27" version="1">MKIFPIKDEELCYELNFVPAFTRYGTDNNKTKRAPFLKSDYGAVRSPLSHEPSAGQLDPFIAERTNRILVPVRFSFVYAHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MCT8</accession>
    <name>A0AAV4MCT8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_168681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002074">
        <property type="protein sequence ID" value="GIX69708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MCT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9853" checksum="2BB834276B3F413A" modified="2024-11-27" version="1">MCWKIRQTFLYEFRNYNGETPEEKRGTGMIELKLNGIGETGVLSFKSHFLKEGNCGTSMQKGLIPPPHVTGVGWLFEERVRGFCGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MEG2</accession>
    <name>A0AAV4MEG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_100841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019674">
        <property type="protein sequence ID" value="GIX70399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MEG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX70399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9756" checksum="82EE47B95446B2AA" modified="2024-11-27" version="1">MAQPKLNDISDARPEAVAYGWLYQNCSCPVQVRRVAVVRIYGCAAILSAESVSSNRPPAIMTRVWLSSPPPVSPSLILALEILGKHIAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIG9</accession>
    <name>A0AAV4MIG9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_95521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002204">
        <property type="protein sequence ID" value="GIX71261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="190"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX71261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="286" mass="31142" checksum="3F65368FADE29DC2" modified="2024-11-27" version="1">MSIESGNCLSKTLIIQSVQHLLKLSAPFNAGILMQKGLLVAEMGLKIKLAVVFVVAAFFTVATSENELLDKKGFAANFDIDTIERGCDCGENSADCYLDLNGVQMCNCTSGYAQLNDSCSECDCGRRSRGCHFDADGNKVCECKRGYFQRFEKCEECDCGGGSTSCRFDQYGVKICNCSSLFAQRNGTCTETCFSDRHCKGRAVCRMGEGGAANFCECPPNYEGEDCEINSLCNRIKPSCYSRGATCEIIDSTAFCRCKPEAAPDLATGLCLCKWKIYLSSGIVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MQZ9</accession>
    <name>A0AAV4MQZ9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_532431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002526">
        <property type="protein sequence ID" value="GIX74773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MQZ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX74773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="21003" checksum="36A9EAC1013B856B" modified="2024-11-27" version="1">MFQFMNLSLLGRRSKFTGGSEVREVSDITETVSCPREVESSVTVPRNTLEFPVEVTDSDNLSDCTVDSEYSFRMGIDSELLDSIDNQVIRHQNILALRDGYSLSQYEEQELETHSYTSRLASLSSENSIQECDLKRNDQTTEKFQKILEDSLLCSICNEAFVKATTLNCCHTFCQYCISEWKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRB7</accession>
    <name>A0AAV4MRB7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_310661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002463">
        <property type="protein sequence ID" value="GIX74007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="12408" checksum="1760E5EA0B583296" modified="2024-11-27" version="1">MPAPFHPFGRWMKFQWTYSGHRDRTVLFLLQDTTLFCFYTSWLSLQGETEIRRVEVSRIANCVLHKDFIIIVFPGIIEPSRLFSLQNDSHTTNKKGPFLSVQRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MS19</accession>
    <name>A0AAV4MS19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Prokineticin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_148349_1</name>
        <name evidence="6" type="ORF">CEXT_428131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002487">
        <property type="protein sequence ID" value="GIX74247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MS19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023569">
        <property type="entry name" value="Prokineticin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06607">
        <property type="entry name" value="Prokineticin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043864923" evidence="4">
        <location>
            <begin position="22"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Prokineticin" evidence="5">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX74247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17556" checksum="3874959DBDFA7CDE" modified="2024-11-27" version="1">MFQKLVFEILLLVFTIGFTTSLQQCNVQEDCELTECCAKRIFKDEAYCVPYRQLNELCLDGGLDEVLYDNKYDITCPCKPGLTCRKIAISDNRGGFNYAGNPRCRNLTADREESKRRTQYRYNSYAGAGGNPAYTYNSQGYGNGIASANAYGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUF4</accession>
    <name>A0AAV4MUF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_602211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020179">
        <property type="protein sequence ID" value="GIX75570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX75570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7712" checksum="FE1AC93BA3F9F886" modified="2024-11-27" version="1">MPAIVRPQSTVEVDESAPRISSRGPLGAGPGPARKWLSCSSTMGPAVCLIMSHKWDFHVNSHIRLISIAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MUX9</accession>
    <name>A0AAV4MUX9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_526731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002658">
        <property type="protein sequence ID" value="GIX76297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MUX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="182" mass="20587" checksum="C2644F0148EC21C2" modified="2024-11-27" version="1">MHMTISAVLRYVTDSAGIYRVGNSIGISRMQDAAQFGALISRKKWKVSGDCRNVPRVGRPMKLGDRDRRMLIREILKNPTQPMALIREEFQQRNGPPSVPSGIRRHFRPEIYEKASVSSAFYTARDSSPESPNDNCTRMQMKLHDSSGMAHRLFLVGLGAISARKSTQRLQFQVRFIQPGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MX82</accession>
    <name>A0AAV4MX82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C16orf52 homolog A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_656211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020259">
        <property type="protein sequence ID" value="GIX76536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MX82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060170">
        <property type="term" value="C:ciliary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045879">
        <property type="term" value="P:negative regulation of smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.150:FF:000006">
        <property type="entry name" value="uncharacterized protein C16orf52 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037663">
        <property type="entry name" value="Mosmo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31186">
        <property type="entry name" value="MODULATOR OF SMOOTHENED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31186:SF1">
        <property type="entry name" value="MODULATOR OF SMOOTHENED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18800">
        <property type="entry name" value="Atthog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="18457" checksum="A1B462B8B15196A8" modified="2024-11-27" version="1">MDRLTAISGGLFLSANFFAIISLVLPDWIVSDVGGNTRLGLLRNCMTIYGRKQLCFAPSLQPEWMLSLICIIIGCICVSSTVGLLLLSHWNEHVVPYARWVGFSAMVLFCLAAVIFPMGFTMEEIGGEAYQLPSSHQVGLSYIFFVLALWITVISELFAGKVCMPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXZ3</accession>
    <name>A0AAV4MXZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_114501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002676">
        <property type="protein sequence ID" value="GIX76580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9377" checksum="E1BC0D254BB2FFB3" modified="2024-11-27" version="1">MLFFQRITEGENLVQDIARGRIYCSVDTIPANIYFDRDVQEMIKTEKHLTMDRKAEGLMLPSASLTRAANIEELRNVFRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N377</accession>
    <name>A0AAV4N377_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_220701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002869">
        <property type="protein sequence ID" value="GIX78784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N377"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11805" checksum="0204115682434329" modified="2024-11-27" version="1">MYLHRHTCLPSKTELSEIKKAKEPQLQLAAEAATKEVIPPPPAPTIPEQPHASKRKNPNYYDDGFQKVTSKKTNPRKGPNQASETITVVRGKRQEILSSYGNTIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEA2</accession>
    <name>A0AAV4NEA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_359901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020837">
        <property type="protein sequence ID" value="GIX83154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8869" checksum="54914352A1168DDC" modified="2024-11-27" version="1">MSTVYIATREKYFLRCDDDRLLCRDDLISIVDELGSVHVMQFVLTDNPTASEVLQYAIRYHDPHWHVCNTNSQIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NM00</accession>
    <name>A0AAV4NM00_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_247341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003546">
        <property type="protein sequence ID" value="GIX85837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NM00"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="63" mass="7184" checksum="AF8FD891BF5AB7BA" modified="2024-11-27" version="1" fragment="single">MHVTSENRDCSKRHISGIESRTVIAQVHKLYVTSESSTTAVEAHKWIQQSRTVICMQEKSQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NP99</accession>
    <name>A0AAV4NP99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_241661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003528">
        <property type="protein sequence ID" value="GIX85608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NP99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX85608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12224" checksum="61C74481C00BCD0A" modified="2024-11-27" version="1">MNQRQNRKREKKKEEKKNSFRRSGLERSSNSMPLQMKAPRLREFSSEFGARQGDGLLAMLFTLALHITIEPILQREAQSSIDPAKSAHMLIFLWSFKETIFEGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NR03</accession>
    <name>A0AAV4NR03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_229301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021167">
        <property type="protein sequence ID" value="GIX86745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NR03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="139" mass="15665" checksum="CFA882A11CEB5FCA" modified="2024-11-27" version="1">MFDTLCEKAWTVVTLECVVAKEVESPLNMRRKRAECILATAPSPNSPFLEASMTKGPIRSRKSLSQFAAPLITPTKQLRVWGIQDLFKSCSIDESNRGLVDHSQRAWRYAFPLISVPQLLKPQHLSKLADAIVKYLLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRI7</accession>
    <name>A0AAV4NRI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_404931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003679">
        <property type="protein sequence ID" value="GIX87422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9791" checksum="8A661525F0A86EB2" modified="2024-11-27" version="1">MGEKNEEACVDNPHHKSCALDPEMRRSGSNTQRWEDEEVPYCYSIYLVIIVWELLCVLHVKFSVNSIGFLWNETLLCGLGKKMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NS24</accession>
    <name>A0AAV4NS24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_598011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021214">
        <property type="protein sequence ID" value="GIX87199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NS24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8652" checksum="A4590B6A3F2ABF93" modified="2024-11-27" version="1">MFTINSGRGYFVIGTQDFRDCGPLVFQRCPRILISVCLRSTFFACWRRYKRALPLLQDNLNFLEEAECALCDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NS56</accession>
    <name>A0AAV4NS56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pol_653</name>
        <name evidence="2" type="ORF">CEXT_94671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003663">
        <property type="protein sequence ID" value="GIX87229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NS56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF2">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="318" mass="36681" checksum="D377C1C2DC0D3C08" modified="2024-11-27" version="1">MTGIEATIINLQPHVIVAGDFNARHTSWNNSHNLTRGNTLKKYIDSKPNTKIIAPTEYTHFNSKNPANNTIIDFALYKNIPFPTAATVKHELNSDHFPVLFDIALSETPHKNPHLVTTDWHNYNYILQHSNLNVINLINTDATDKAIANFTKTLYTAFDKSSKPKNFPLINKLPRNIKSEIKKRNYYYRRLWQRTKDPEIKRQFKAHHANIKKLLKTLNNKNWEDTTNSYTHNSTALWRKIKTLRNSSENIPPLNTTSGNMAISPAEKAESIADCWEKQFELNDMSDDISDNYIIHQNTLYFNSPIVPIITTPSPRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSR0</accession>
    <name>A0AAV4NSR0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_404891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003679">
        <property type="protein sequence ID" value="GIX87413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSR0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="221" mass="25915" checksum="03240364967A3692" modified="2024-11-27" version="1">MRKETRIPLRNCPLNNAIHLSFQNSQSGKTVFILHKREKLWREELSCISFFRLRILLFFWGRCRTPSIASPKEETLESPRILTIPTSREKRGPLGNILSCTTNIIYRFFYNKRIGFLFEWVASGCDITSTYRSEYSTMHLVLVIEIHDMTLLAIFKPLQTHSSVCPASFSYRKPFLTIHQTYSGRYHQLRAKVLSTYTYNPCNLNSKHPRALLFTRAERTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWF7</accession>
    <name>A0AAV4NWF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_759581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003823">
        <property type="protein sequence ID" value="GIX89068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="29" mass="3109" checksum="9D0D73BB2A0EEA6A" modified="2024-11-27" version="1" fragment="single">AELLGCDPIRLVRSVDLATEDLPIGRQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NWG9</accession>
    <name>A0AAV4NWG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_404821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003679">
        <property type="protein sequence ID" value="GIX87402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NWG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17511" checksum="735F6ECBC598B899" modified="2024-11-27" version="1">MSQSVYVPVIKLLTDRQTTLLISLSCMVNKEGIKQSRSPQEPWSIPGTYNPAPPLTPEREAEWTQSNYYKTQSTLIEKRNFYNFLHRYPPLSDLETITQPAKTLVKSGVLTTPSHSCEEAEWTQKVITGAPSSIQFPLELPRLLNEKTFPNSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXA3</accession>
    <name>A0AAV4NXA3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_710191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003782">
        <property type="protein sequence ID" value="GIX88566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXA3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12958" checksum="5904193EC19A0DA1" modified="2024-11-27" version="1">MGVITRVIIPDSFAESASLEEQWGSAVANRMNNGGEFGQDKCTREDLHMKFMARFRMNPANRFYRKAHSKVAVVQSTAKLFRPPLTSAPWGKRNFDSGLSAQQFHLVYGLNLPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NY04</accession>
    <name>A0AAV4NY04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_197601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003786">
        <property type="protein sequence ID" value="GIX88610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NY04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15363" checksum="7FC59623A64C9990" modified="2024-11-27" version="1">MDAIRATSNSTANILLDWSDCSRFVGGAFSRKGTVNMLNPFVSEDILHPIFGTSYILYLGYSTSCIWDILHPIFGTSYILYLGYSTPCIWDILHLVFGIFYILYLGHPTSYIWDILHPIFGTSYILYLGYSTSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZ71</accession>
    <name>A0AAV4NZ71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_759601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003823">
        <property type="protein sequence ID" value="GIX89073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZ71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="12655" checksum="620A2375FBA208F8" modified="2024-11-27" version="1">MCENKQMQITVFQQKSSSAALCPMWAKICASNILDDSEGLFEWIFAVKTMHVMKRLNEYQPGAGVTIIILIVSLNQRSSCILYIITGYLYTLADYSSVAVIGELEVQSAPHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1I0</accession>
    <name>A0AAV4P1I0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_126571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021500">
        <property type="protein sequence ID" value="GIX90413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1I0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17656" checksum="FB678940630D286E" modified="2024-11-27" version="1">MCKNSILRGRVKAYKCFWSEKLDEMKAKRDRLRRKAELSKRQSDMVLWRKQVALFKKAILEAKRKCFNDFIYNINYKEDSMKTYKFLSTLQNKRPVPKKEPIYFNGAILTSDKAVANTFGQSYAKNQEKGPFARKCQVKLKEIRDAEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P680</accession>
    <name>A0AAV4P680_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF5641 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_1927_1</name>
        <name evidence="3" type="ORF">CEXT_476901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021656">
        <property type="protein sequence ID" value="GIX92085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P680"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040676">
        <property type="entry name" value="DUF5641"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF5">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18701">
        <property type="entry name" value="DUF5641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5641" evidence="2">
        <location>
            <begin position="32"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX92085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="192" mass="22573" checksum="4AE33220CF9B1E8C" modified="2024-11-27" version="1">MRAVKPSDFIQDIKGNETMDLDTVDDKHLRKRIRYLQNLRYQLRQRFQKEYLSELIRSPQSFSKRRNLSPGDIVLVDSDNTKRLNWPLGSFIELFQGKDNVERVARLRVAKGKIIRLIQRIYPLELSSPEIVPINDVPVRVKDSSDTSDNDNQHTVSNEQSFESKDLPKEQLETLKRSRFVRQIVPVKRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6S4</accession>
    <name>A0AAV4P6S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_356861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004052">
        <property type="protein sequence ID" value="GIX91713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="130" mass="15173" checksum="744D42F8F082DEB8" modified="2024-11-27" version="1">MDVIYYGVKIDIKTTIVKVREGKGVQQDYWTLLLWHYHPYSFKVRLGAQRDNLHHRLATQRLQLQIVHHGLLRARFHGAAGHHRHLLLRHCPSHPQEHRRQAEGGGSRSVDERKVHHSCKYICSPNSAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBD9</accession>
    <name>A0AAV4PBD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AVEN_254530_1</name>
        <name evidence="5" type="ORF">CEXT_73881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004231">
        <property type="protein sequence ID" value="GIX93303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF317">
        <property type="entry name" value="TRANSCRIPTION FACTOR SOX-15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="209"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="209"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="152"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX93303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="245" mass="27080" checksum="13FE8C6E1D295A61" modified="2024-11-27" version="1">MPNSGERPPVSGFNGGNQANLPILDSTLYQILGEKEVRESFLTVCVPVGVVRLWHSVWRRAKIQWEKQPFSELSIRHPLSILKVILNCDKLVQQTQADKLVVEQDGNVPLSAKPVMYNSGVNYRGSEDGWGMVYPHYSYKCSAYQEENSVTPIPWTPEMSNMSDDSPPPPMEGDEEPASPMPTPTSRGGGRGSGGGKSSAAAAALEQRIRRPMNAFMVWAKSERKRLADENPDMHNADLSKLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PK96</accession>
    <name>A0AAV4PK96_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Crebbp_0</name>
        <name evidence="11" type="ORF">CEXT_29121</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01004626">
        <property type="protein sequence ID" value="GIX96284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PK96"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003101">
        <property type="entry name" value="KIX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02172">
        <property type="entry name" value="KIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47040">
        <property type="entry name" value="Kix domain of CBP (creb binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50952">
        <property type="entry name" value="KIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KIX" evidence="10">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="73"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIX96284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="351" mass="39359" checksum="FA56709344567DF3" modified="2024-11-27" version="1">MDLRHHLVQKIVQTIFPAVDINTLKDSRMVSLVSYAEKVERDMYKNANSKEEYYQLLAEKIYKIQKELEDKRQKEKENQLQQQEVGSSLEPILNNTGTASPKPNIMGNASQSHLPGPSNFDNQQRMPPPNITVSAGIGARASDLFSRSQLSNSTVNQNSLNQIQIRMQQQNSLSSMNLQQQQLPQQHFNNLNTVTSMSMPSGDQSSITAALSGSVSQFNATLQKVHTQMANSTLQQNQLQLTNSTLQQNQLQMTNTSLNQNHLQMANSPLQQNHMQMANSPLQQNHLQMTNSPLQNQMSMVNSSMQQNHLQMTNSSLQQNHLQMSNSSVPQNQQMGEFISPAESPSNAICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQG8</accession>
    <name>A0AAV4PQG8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mcm7-b</name>
        <name evidence="5" type="ORF">CEXT_533711</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01004852">
        <property type="protein sequence ID" value="GIX98051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX98051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="15972" checksum="BC9FB011E4FFE67D" modified="2024-11-27" version="1">MKIRGNINICLMGDDGVAKSQLLSFIDRLATRSVGLTVSVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMMDSDRTAIFKSYGTANHFHCKVVVTQYFLHFKAGILTILNARVSILADYRRYNPKRSIEQNIQATSCIVVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRJ1</accession>
    <name>A0AAV4PRJ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_676041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005063">
        <property type="protein sequence ID" value="GIX99550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRJ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="7985" checksum="233EF6C3FBC14FE3" modified="2024-11-27" version="1" fragment="single">MLGGRMGIKLGDADQRSKAPCPQIIAWSPLSLIYLADANENLSVEDLQLGVCRERETRNAEGRAARKAKSRGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRS9</accession>
    <name>A0AAV4PRS9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exophilin 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_266201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004925">
        <property type="protein sequence ID" value="GIX98531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="45255" checksum="EB817BDE666C95FE" modified="2024-11-27" version="1">MSPTACNYLPKCRKAAVCPVESDLAMLKANRIDGEAYGDSHSSIMPLARSSYKYFLNRYKMTSTNKTTSTPQTDSPDNDSEVSNLADLNSDRQSSVISKSANVNFALEHNSISKHSFENILEPNLKAPICKYESESCLSIFDGGSTEIAPYTLVNSEETGDSGKQNRVKFPEKNESVFPEKEAVSEQYFTDYDDILKQNNNKEDDVNLKQSNNNEDDSAMNHCETENFTLNFSDFLNVNKIYQTNNSIHKAYEVKSEIEKSKLKETSSSLNCDTIYNMNPFSSFKGFSYKRSQTKNLNETEKSFTTTLENYNETQTKMESYKTENFTTFSALPNTTKSNETFCNFSNNNASTVKIESNSTDSCSAECRSLEDNAIEKQPKERFHNLVQEKNFSLFRCYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTS3</accession>
    <name>A0AAV4PTS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_280591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004935">
        <property type="protein sequence ID" value="GIX98607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15850" checksum="F9C26E914E69D232" modified="2024-11-27" version="1">MHSKEEYKTKSSLKTQNSKFSIERSSFYLYLLTIPILSAPSLFPGSQQFEIPQFNPKNPFPTHPFVVLLQKSTSVTAHSIHKFQAPLAIDAGSISRTPTQPLPLCCVRWSFVPHSLFESSVKNPRFFISLSHLNARVMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QCS4</accession>
    <name>A0AAV4QCS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_156101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005923">
        <property type="protein sequence ID" value="GIY06102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QCS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12617" checksum="5C65BA57488EE012" modified="2024-11-27" version="1">MSARRMQATSHDSVSRRVSRITTIIHGMVRQKLACSERAGELTACQPASTVNPARGIRGRPWQTMKQPLGAASRLRLMGERAGASPRGQHEAASGGGILDYASSRTDPTGKNASCFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QH52</accession>
    <name>A0AAV4QH52_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Probable ATP-dependent RNA helicase DDX23</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DEAD box protein 23</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">DDX23</name>
        <name evidence="23" type="ORF">CEXT_693281</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation. Independently of its spliceosome formation function, required for the suppression of incorrect R-loops formed during transcription; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">The phosphorylated form (by SRPK2) is a component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, WDR57, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39. Identified in the spliceosome C complex. Interacts with ERBB4. Interacts with ERCC6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01005984">
        <property type="protein sequence ID" value="GIY06648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QH52"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17945">
        <property type="entry name" value="DEADc_DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000322">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000520">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057479">
        <property type="entry name" value="PRP28/DDX23-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25430">
        <property type="entry name" value="DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 17 23" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="22">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="20">
        <location>
            <begin position="388"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="21">
        <location>
            <begin position="603"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="16">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="55"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="129"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00055288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00062365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00075448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="GIY06648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="785" mass="91913" checksum="211637FB3332F6A7" modified="2024-11-27" version="1">MDYVDKHNSERPVDRLRSEKKRRSRSHSPRRHKRSRSRERRTRSRSRERHRHKERDRERDKNRSKDKSRDKDRSKRKDKYKDKNHVKNGTEEEEAKNEKVKKEPLSLEELMAKRQAEEQARSKPVFLTKEQRAAEALKRRQQEVDEQRKRMEEERKIRMQFMEEAKHSQENDKERERRERREKREAEEANALATTAETDRDKIREIKDKEKELEAIRERYLGLMKKKRRVRRLNDRKFVFDWDASEDTAVDYNPIYKERHTVQFFGRGHVAGIDLKSQKKEQSKFYGELLEMRRTVAEKEQEILRLKKIKSKEEKQKWDDRHWTRKSLEEMTERDWRIFREDFNIAIKGGRIPNPLRKWKESGLPKSILDIIEQLGYKDPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLVWITSLPKKFRNEDIDQGPYAIIMAPTRELAQQIEEETIKFAKTLEIRTVAVIGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNRCTYIVLDEADRMIDMGFEPEVQKILEYMPVTNQKPDTDEAEDEEKLLANFNSKNKYRQTVMFTATMPPAVERLARSYLRRPSIVYIGSAGKPVERVEQIVYVVSESNKRKKLLEILNEGIEPPVIIFVNQKKGADVLAKGLEKMGFNACTLHGGKGQEQREYALASLKTGSKDILVATDVAGRGIDIQNVSMVINYDMAKSIEDYTHRIGRTGRAGKHGIAVTLVTKEDSHLFYDLKQLVMSSPISTCPPELANHPDAQHKPGTVITKKRREEKIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUK6</accession>
    <name>A0AAV4QUK6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_340321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006992">
        <property type="protein sequence ID" value="GIY13733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUK6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12226" checksum="15983CC3EDBB741C" modified="2024-11-27" version="1">MLSKGRFKRSYISATSFTLVEFQLTSSSESAENVSYLHCLSGSDGVEKEGNLQEVADSPDISISEFLSRANEEFLPKCSCIGTFTSISSIIFIAASEMLRNTFDFSDISPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXM9</accession>
    <name>A0AAV4QXM9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_688961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007035">
        <property type="protein sequence ID" value="GIY14020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXM9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12181" checksum="185D61BF146B6B62" modified="2024-11-27" version="1">MLCKDSFRFNIAHRMQHSKNSSLASIDILKDTDQEFSINRSFLQTYYETLAFSFGLSDKVPTTYCTLARNAPQITKATFQYLITLFIEMTVLKIPILLWHCSFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZS6</accession>
    <name>A0AAV4QZS6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="16">PARP</shortName>
            <ecNumber evidence="16">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">Tnks2</name>
        <name evidence="19" type="ORF">CEXT_739451</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="14">Homotetramer in membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Target cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cationic peptide 01 (latrotoxin) family. 03 (alpha-latrotoxin) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="16"/>
    <dbReference type="EMBL" id="BPLR01007243">
        <property type="protein sequence ID" value="GIY15533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044231">
        <property type="term" value="C:host cell presynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044218">
        <property type="term" value="C:other organism cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09524">
        <property type="entry name" value="SAM_tankyrase1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01438">
        <property type="entry name" value="tankyrase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000012">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000009">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000356">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.228.10:FF:000001">
        <property type="entry name" value="Poly [ADP-ribose] polymerase tankyrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0528">Neurotoxin</keyword>
    <keyword evidence="9" id="KW-0638">Presynaptic neurotoxin</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-1052">Target cell membrane</keyword>
    <keyword evidence="12" id="KW-1053">Target membrane</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="140"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="264"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="364"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="441"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="474"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="15">
        <location>
            <begin position="507"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="17">
        <location>
            <begin position="664"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="18">
        <location>
            <begin position="741"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="GIY15533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="952" mass="104686" checksum="BF183B051A93FC68" modified="2024-11-27" version="1">MSIIVVLLQHGADPSIRNTDGKAALDLADPSARSVLTGEYRKDELLEAARSGNDEKLMQLLTPINVNCHASDGRKSTPLHLAAGYNRIRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTEILIKHGANVNAMDLWQFTPLHEAASKARIEVCSLLLSHGADPTLLNCHSKSAIDVASARELQKDFLVDEYKGHCLLEAARLADPARVKKYLSLDIINFKHPFTHDTPLHCVVSSPYPKRKHVTEVFIRKGASLNEKNKEFLTPLHVAADKSHFDVLDVLLKHGAKVNTLDALDKQLCTGYTAAQVANESVQKLLSEPTNVGMDIEYQLLEAAKAGDTEVVKRILATHLPVVNCRDVDGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGYGANVNVADLWKFTPLHEAAAKGKYEIVKLLLKKTLICRDSQGRNSTPLHLAAGYNNLDVAEFLLEHGADVNAQDKGGLIPLHNASSYGHLDIAALLIKYNTVVNATDRWGFTPLHEAAQKGRTQLCALLLAHGADPTMKNHEGQTPFDLATAEDVKCLLMDAMPPTTLPPTTKSSAIGASVLPVIASPKSCMLSKTKKWREKCSISSTNFKFSCHWAGGRYSLSLNLFSSQKASASMSASGSQHGDGCVDFDRAEAPDPTMENVGISGFLMSLGLDHLSDTFEKEQITLDILAEMGHEELKQIGVNAYGHRHKLLKGIEKLYMGHNSATFMPNKPGTVLVELCPEDKEYQAVDDEMQATIREHRDNGHAGGIFSRYNILKIQKVRNKKLWEKYCHRRKEVAEENHSQSNERMLFHGSPFINAIVQKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPLHKDRSCYICQRQLLFCRVTLGKSFLQFSAMKMAHAPPGHHSVIGRPSVGGLSYPEYVVYRGEQAYPEYLITYQIAKPDAEPSPSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZX4</accession>
    <name>A0AAV4QZX4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">Tim10</name>
        <name evidence="16" type="ORF">CEXT_199901</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Mitochondrion inner membrane</location>
            <topology evidence="1 14">Peripheral membrane protein</topology>
            <orientation evidence="1 14">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007007">
        <property type="protein sequence ID" value="GIY13851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZX4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.810:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038:SF16">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="15">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY13851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10755" checksum="9612C15BCB983DCB" modified="2024-11-27" version="1">MAANPAIQLDASKLELVQNLELEMMSDMYNRMTGACNRKCIAPKYSEAELSKGESVCLDRCVAKYLEVHERIGKKLTAMNTDEEAVKKILEQNNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4A6</accession>
    <name>A0AAV4R4A6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_132311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007167">
        <property type="protein sequence ID" value="GIY14913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4A6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12757" checksum="885018F977D12DB8" modified="2024-11-27" version="1">MYGDDWGFSPLKSKLFGVRSSSMLAKSRAYLLGVYQESTVARNDYTSERLSLLECVCLKAVLLRIHQNPSLNLYIIPLEKRVHGCHSNANMNRYSREPDTLCSMVSFEISPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8U9</accession>
    <name>A0AAV4R8U9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fucosyltransferase</fullName>
            <ecNumber evidence="7">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FucTC</name>
        <name evidence="9" type="ORF">CEXT_37671</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">Golgi stack membrane</location>
            <topology evidence="7">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="7"/>
    <dbReference type="EMBL" id="BPLR01007512">
        <property type="protein sequence ID" value="GIY17459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8U9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="8">
        <location>
            <begin position="53"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY17459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="212" mass="25068" checksum="FC4198FB36137ED8" modified="2024-11-27" version="1">MYRCPTDSLVKSNPVIKTSVLEKRLDSLRTKKNKAVWFVSNCKTDSNRGTGGDQRCYEKIAIKYKFYLAFENAICQDYATEKLFNSLNYDIVPVVLGGANYSSIVPPHSVINAMDFSDPEKLGMHLWEVSRNDELYLSYFNWKNTYRSYLQPWMCDLCAKLHENFQPQVKRNLDSWWYEDFTCKRWANNSFEYVNEHVFPVFHSKIFQQKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4REE4</accession>
    <name>A0AAV4REE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_13201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007631">
        <property type="protein sequence ID" value="GIY18477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4REE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY18477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15352" checksum="ADF5E53B88D02616" modified="2024-11-27" version="1" fragment="single">TLAKRISESKSELLFAYSHLMLLLVAIRLCRKHLIFIDLNLQPVKLKSKAADLSGKAVKPFSNKENYKRPKDGKNLYIISNSSSFKNGPNQNARQKNLNKYNRIMTKIYSQRLKTETLKGKVNHQRHEILINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFL6</accession>
    <name>A0AAV4RFL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_659111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007864">
        <property type="protein sequence ID" value="GIY20275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="44" mass="5219" checksum="813A0760FD9A8993" modified="2024-11-27" version="1" fragment="single">MSICRPTSETKQKVSVQYQRWYDKSRRLEKFSTYSLNIFEVGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNF9</accession>
    <name>A0AAV4RNF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Svep1_15</name>
        <name evidence="11" type="ORF">CEXT_321191</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008089">
        <property type="protein sequence ID" value="GIY22007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000037">
        <property type="entry name" value="Signal peptide, CUB domain and EGF-like domain-containing 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000119">
        <property type="entry name" value="vitamin K-dependent protein S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000240">
        <property type="entry name" value="Vitamin K-dependent protein S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050751">
        <property type="entry name" value="ECM_structural_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003410">
        <property type="entry name" value="HYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24034:SF89">
        <property type="entry name" value="COMPLEMENT COMPONENT C1Q RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24034">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12661">
        <property type="entry name" value="hEGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02494">
        <property type="entry name" value="HYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50825">
        <property type="entry name" value="HYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="221"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="412"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="502"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="10">
        <location>
            <begin position="734"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="10">
        <location>
            <begin position="799"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="domain" description="HYR" evidence="9">
        <location>
            <begin position="941"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY22007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1102" mass="121935" checksum="5975B5D39464C8CA" modified="2024-11-27" version="1">MHKILLTIQIQYRTAQQEVLSSQVSYISNEFTLPLILETRRTCAHRNGFCSQICSEDEHRGVQCSCREGFKLLWDKITCDEVSASTYSRPRSCADSNGFCSQVCRNVNHGVRCSCRTGFQLLSDKRTCVDIDECSSGAFECFRCVNTPGSYECLCPEGFRSISAIQCESCRKNSYKSVTDAFCIDCPSDSQTVGEGKTSIRDCICNSGFTGNPALGIPCKDIDECKRNTHYCQQECRNSIGSYTCACRQGFKLIDRYQCEEIAEPVDSRSTVQLSCADHNGLCSHVCSDEEFGGVRCSCPEGFRLLWNNRTCEEISISNEFTLPLILETRRTCAHRNGFCSQTCSEDEHWGVQCSCREGFKLLWDKITLRRPLTCADSNGFCSQDCSNLKSGVRCSCRRGFQLLSDKRTCVDIDECSSGEFECFRCVNTPGSYECLCPEGFVARAIQCEKVIVPTDSRPTVPRSCADSNGFCSHVCRKWHSGIQCSCPEGFRLLPDRRTCVDVDECANSVLNKCDHDCHNTEGGYSCSCRAGYISYDGFKCEGCRKNSYKSVTDASCIDCPSDSQTDGVGKTSVRDCICYPGFTGNPARGIPCKDINECAALDNFGCSDNCLNVPGSAICTCFPGFQLQEDQKTCSDIDECSIKNGGCDGVCHNTVGNFTCSCDEGYVPSEVDRYSCVDVDECKENNGGCVDICENFQGGYQCLCSEGYHAHPDGKSCIAIHCPKVYVPHHSSLRCKDSPRSNRTVYRSGIVPEDIQFPVGALCKVKCDKGYDLHPSSHPIICQNNGKWNATPPECQVLQCPPLLPPEHGDVYPPSCKDGTVQVKEKCIFTCLQGFRITGQEVFTCNNNLKWDVKNGTQCLPETDAFIVCSEDITVELMPNETSAEIFLIPPKSNIEPILVRPDWISLDRVNFFPAEETKVMFYVEDSYNKAECNISVFVIDKEPPFFLDCPETLSVTGSGSQGTVVDWQEPIADDNVGIASITKTLEPNSTLYSGIHLVQYVARDFAGNMGMCSFEINITSEGCSELADPLNGEANCFEWTSGMICTPLCDLNFTRPPEEPEFYTCEDSGSWTPSDFISPCLPESLLHLEQTGNFTDAVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S3Y9</accession>
    <name>A0AAV4S3Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipocln_cytosolic_FA-bd_dom domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_32326_1</name>
        <name evidence="4" type="ORF">CEXT_585061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008836">
        <property type="protein sequence ID" value="GIY27654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S3Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00179">
        <property type="entry name" value="LIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="155"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY27654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="305" mass="34709" checksum="EFD7B604C4DF5724" modified="2024-11-27" version="1">MILLRKSPLWVLDTDYETYAVTYTCNDSSSKVSVMILSRTNKRDEKEDNGNRRYAISTKCKSHGPTIIINHDEKHYGIFEWNEETKAFLLNKFVLIVIDKWKSDYSDLTTPQNVELATLSMNSLKGTVSATVGLAAIGSCPTPKVQADFQLEKFAGTWYVIETSSALDKVGKKCSLYKVEIKNPTKASTLHKFVSSITDKWKSEYSELSTPKKNEPAKLLVSPLKGTILARKYPLWVIDTDYDTHAIVYSCQSLLVAYTEDVWILSRTKTLDDEKKMKLYEVLKQRDINQKGLSEISQSEKDCKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7X6</accession>
    <name>A0AAV4S7X6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small ribosomal subunit protein bS6m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">28S ribosomal protein S6, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mRpS6</name>
        <name evidence="4" type="ORF">CEXT_415881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009251">
        <property type="protein sequence ID" value="GIY30578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7X6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY30578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17294" checksum="C31CCAC6124B6DAC" modified="2024-11-27" version="1">MPSLELSLIMKTLPKQELAAALKRVGTLLLEKGSVIEKLENVGTRELPVRIRKEGVYHYKGSYFVYTFMGQRVIHKDLDEMCKLDTDILKHGLVLPLSPPEKCTLEEELQPPALRKSVQNLLNESKKHKGISQPYYKHIKEYDYYDIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S915</accession>
    <name>A0AAV4S915_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dhrs9</name>
        <name evidence="3" type="ORF">CEXT_174271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009167">
        <property type="protein sequence ID" value="GIY30022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S915"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF50">
        <property type="entry name" value="GH26015P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY30022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="355" mass="40250" checksum="99770CED38C4FEFF" modified="2024-11-27" version="1">MVGGCIQYKKIRDLDTSKGLKMIMFVLDFLTNLILDCRFQIVVGFSFLIHWAWRLPRPRKGAGNKTVFITGCDSGMGHRMARRFDEMGMHVFAGCLQPKGEGALALKKSCSTRLHIVPVDITRDDLVLKAVDYVKANLPPGDKGLYCLVNNAGVLAFTDFELMTPSMCEEVININLLGTMRVTKHFLPLICQVPGRVVTITSILARLVYPGVAVYAATKHGLNGFFSALRYELQEKGVHVATVEPGDFSTTTDIMQWTQRHLEEIWNNLSPEEKKSKLHLFEKTKKKVHKTKCSEKVQEKNYKFLLQDVEDAMLAEEPHWRYVSAPTATKIVLWILRSLPEKWSFKLMGEKTISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJF7</accession>
    <name>A0AAV4SJF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_292241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009784">
        <property type="protein sequence ID" value="GIY34558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11853" checksum="FF98023522454306" modified="2024-11-27" version="1">MDLQKIFKRGASKLHFEMQVAFFFLLLTLAHYPPSHYFRLSRSPGMFMHEAAEGITRALNFSLQKFGSIHNEVRLGISNRLVTTKVNHHILPHVYFTINPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SL29</accession>
    <name>A0AAV4SL29_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thyroglobulin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_80935_1</name>
        <name evidence="7" type="ORF">CEXT_146261</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009809">
        <property type="protein sequence ID" value="GIY34800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SL29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00191">
        <property type="entry name" value="TY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.10">
        <property type="entry name" value="Thyroglobulin type-1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051950">
        <property type="entry name" value="Dev_reg/Prot_inhib"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000716">
        <property type="entry name" value="Thyroglobulin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036857">
        <property type="entry name" value="Thyroglobulin_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12352:SF3">
        <property type="entry name" value="NIDOGEN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12352">
        <property type="entry name" value="SECRETED MODULAR CALCIUM-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00086">
        <property type="entry name" value="Thyroglobulin_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00211">
        <property type="entry name" value="TY"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57610">
        <property type="entry name" value="Thyroglobulin type-1 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51162">
        <property type="entry name" value="THYROGLOBULIN_1_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Thyroglobulin type-1" evidence="6">
        <location>
            <begin position="145"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Thyroglobulin type-1" evidence="6">
        <location>
            <begin position="255"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Thyroglobulin type-1" evidence="6">
        <location>
            <begin position="330"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="349"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY34800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="381" mass="43000" checksum="A4E600451CC9A5E9" modified="2024-11-27" version="1">MFYFTDFTRQDVLLCADDGFFAPLQCSEITNNCWIPTHKHNLFNLGNKVPLQFEEMNTLGIILLSCFLPAALCWTYQDDYADCPTALKELSKDPEDKWMAPKCNADGTYQNLQCFPDHPVYPKSCMCVTSWGYTLRESLLKPLDTCVCELYKYDFFVNPYVDGTMTPNCADDGSFAPVQCRRGTYYEDVFCWCVDRNGNKISSEERKEDISCDHKRKPSYYGFPVRLKMKIFAVVAIISCLLPASLCWDFPGYPGVDCPTARQKILEDPTSQWMVPKCNEDGTFQDKQCYDIESPDACMCVAPDGTALTLAGFGIDIETCICLTASYDVKDPDEEPNCAKGGYFAPLQCSKRRGDCWCVDKYGKVLVPPSKDVHSCDNVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SNS5</accession>
    <name>A0AAV4SNS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_742031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009623">
        <property type="protein sequence ID" value="GIY33303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SNS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9872" checksum="D05FFF9D27BB33C9" modified="2024-11-27" version="1">MLPLEAWCHDVEQGHDPQIGTHFLWDSGTTPCVPARLVAGWIERQSSHSATGRADWVVHQAKKISKGREGKKDVFYRSIQNHIHTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWS5</accession>
    <name>A0AAV4SWS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_166661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010212">
        <property type="protein sequence ID" value="GIY37739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10852" checksum="D2D7CEA375A54EA0" modified="2024-11-27" version="1">MMVMSHFSGDCSASTDPLEILFFKEKGHIFQPLSVRGAFSVRVSLAQLRGFLFKRSRYLQKGISELINLSLMTAPPSGKNEFPPSIVRFKSEPKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWZ8</accession>
    <name>A0AAV4SWZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_299211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010342">
        <property type="protein sequence ID" value="GIY38670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11881" checksum="FEE63B42A387E19F" modified="2024-11-27" version="1">MKYKYFILLPADHDDEVRNRFEPRSDQKTKAPFYQSFCKRKGETAISSEERKEKKTAENETKRVSESMLSNITPEGVHLSYFWGPSISLITRQNRDSTCATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY11</accession>
    <name>A0AAV4SY11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_390151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010055">
        <property type="protein sequence ID" value="GIY36483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="296" mass="33912" checksum="614CFFED21B56338" modified="2024-11-27" version="1">MLQIAHHCMVGMRRSKDDYNSRFSAAFDFPIVITEDTAFPLNCRISRCVANRTTMVLNWLEITDNELLTWTEVIRSIAEKVSQDARDHFIDAWCDWLTPEELAEKGTLMTQARTSKDKQGAEDKQGAEVEQRRHCDKTYKKSTTQNDSKSALPGVPSQSRRDTIDMDRSLPSCYGYKGPGKNGLIFNNGAVSLRACTKTEILTTTVDIDVKGKVTSTYSLENCQGKPNSSWSRFFSAQQESFWIFRMLKKFWMIKNMRNVSNQRGREQIPFIENRIDTGDHLPDAVPLYRMVPTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7P2</accession>
    <name>A0AAV4T7P2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_738051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010831">
        <property type="protein sequence ID" value="GIY42300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7P2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="11068" checksum="8A2B28207FD66F32" modified="2024-11-27" version="1">MINAYNKSFRHKIRNNMYHNLNKLRDIIIRRFSDSFELPSFHFHLDSNDSSDYDSFHRNPSVYVSEKRLLIVITFSNVAHQRVMRSHDGIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7V4</accession>
    <name>A0AAV4T7V4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_668641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010669">
        <property type="protein sequence ID" value="GIY40850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7V4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11573" checksum="2C22748A9F31DBBD" modified="2024-11-27" version="1">MKFWDGKSASTSHYRTSFRRAGEEARTGHPLTARRKEGQSPPLSGTMRVPRSRTLPTGWYCPAEPLFFLHVLHTKREQDTGTYWCLATNEVERQKAETPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9B3</accession>
    <name>A0AAV4T9B3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Signal transducer and activator of transcription</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">STAT5B</name>
        <name evidence="16" type="ORF">CEXT_389132</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="12">Forms a homodimer or a heterodimer with a related family member.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the transcription factor STAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010902">
        <property type="protein sequence ID" value="GIY42855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9B3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09919">
        <property type="entry name" value="SH2_STAT_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16855">
        <property type="entry name" value="STAT5_CCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000029">
        <property type="entry name" value="Signal transducer and transcription activator 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.630:FF:000003">
        <property type="entry name" value="Signal transducer and transcription activator 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.20">
        <property type="entry name" value="STAT transcription factor, all-alpha domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.630">
        <property type="entry name" value="STAT transcription factor, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.532.10">
        <property type="entry name" value="STAT transcription factor, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001217">
        <property type="entry name" value="STAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046994">
        <property type="entry name" value="STAT5_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048988">
        <property type="entry name" value="STAT_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036535">
        <property type="entry name" value="STAT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013800">
        <property type="entry name" value="STAT_TF_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015988">
        <property type="entry name" value="STAT_TF_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013801">
        <property type="entry name" value="STAT_TF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012345">
        <property type="entry name" value="STAT_TF_DNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013799">
        <property type="entry name" value="STAT_TF_prot_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11801">
        <property type="entry name" value="SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01017">
        <property type="entry name" value="STAT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02864">
        <property type="entry name" value="STAT_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02865">
        <property type="entry name" value="STAT_int"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21354">
        <property type="entry name" value="STAT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00964">
        <property type="entry name" value="STAT_int"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47655">
        <property type="entry name" value="STAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48092">
        <property type="entry name" value="Transcription factor STAT-4 N-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0010">Activator</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 14" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SH2" evidence="15">
        <location>
            <begin position="583"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00064301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU046415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY42855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="685" mass="78499" checksum="3EB4975C4F6F093A" modified="2024-11-27" version="1">MTGCRQSLSEQSIDGYEGHCNLKCKPHPDMSNNSTLINHMALWARVQQLHGEALQQIGLLYGDNFPIDEAEMDPDNPQHDVYIGQIINNFFSQLEAKQENVDFLTRLKLNEAVNEFRAKYSNNPQHLVRIIKHCLNSEMRIVQQTENYLRGGSTAMHLPPDPIQEISVALDKLRHRTQESGEDLRKMIQCQEAFVIQYQESSKPQIQQSSDVEFIAKLQKEKQLYDNAVRNHIQELMRLRMKLGQHFTQQLHGNGEPFHNNLDQIQEWCEALADIIWQNRQQIRQVESLVTQVPILEILWKKLPMLNSSITGLLSSLVTSTFIIEKQPPQVLKTNTRFSATVRLLVGSKLSVYMTPPQVKVTIISEAQAIALLKNDKVGPGEASGEILNNMGTMEYHQATRQLSVSFRNLLKKKGTESVMDEKFSLLFQSQFKVGGGELVFQVWTLSLPVVVIVHGNQDPHAWATITWDNAFAEPVCSLLFALFKNKCMGRVPFQVPDKVRWKEVADVLSTKFKSGTGRALSEDNLQFLAGKVFQVTSGFVDPESQVTWSQFCKEPLPERNFTFWEWFYAIMKVTREHLRNLWNDGLIIGFIGRHQAEEMLLQKCNGTFLLRFSDSEAGGVTIAWVADSQTREGQEVFMVQPFTSRDFAIRAISDRISDLKTLLYLYPDIPKDQAFWKILYTIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9U5</accession>
    <name>A0AAV4T9U5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Probable galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UDP-glucose--hexose-1-phosphate uridylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">GALT</name>
        <name evidence="16" type="ORF">CEXT_754401</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="5"/>
    <dbReference type="EMBL" id="BPLR01010816">
        <property type="protein sequence ID" value="GIY42202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000001">
        <property type="entry name" value="Galactose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943:SF1">
        <property type="entry name" value="GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Galactose-1-phosphate uridyl transferase N-terminal" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose-1-phosphate uridyl transferase C-terminal" evidence="15">
        <location>
            <begin position="26"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00071281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY42202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="194" mass="22793" checksum="8CE4625297528C84" modified="2024-11-27" version="1">MGCSNPHPHCQIWASSFLPDEPRIEDKQQCEYFMKNNSILLLDYLKEELKTMERIVLSNEDWVVVVPYWAVWPYEVMLLPKRHILKISDLTEKEKHSLATIMKKLLTKYDNLFNTTFPYSMGWHGAPTGLDKTDYSYWQLHASYYPPLLRSATIKKFMVGYEMLAQAQRDLTPEQAAAKLRSLSEEHYKLAKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TAI7</accession>
    <name>A0AAV4TAI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_167131_1</name>
        <name evidence="1" type="ORF">CEXT_539551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010928">
        <property type="protein sequence ID" value="GIY43090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TAI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11233" checksum="CA0DFE18A1E8E9C3" modified="2024-11-27" version="1">MNGSLCFREADRQQFAQKLCRSEEDCDWDQCCIDAQTRIPGFHGICHNPTGRGEYCNPDPNDRTEEGRYKEACPCDKGLNCKSKEEIIGGKTRNFHVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJM1</accession>
    <name>A0AAV4TJM1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_674671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011294">
        <property type="protein sequence ID" value="GIY45596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17627" checksum="6933023E2EFB5A8D" modified="2024-11-27" version="1">MYCPNFPIPAGFKGKKIYDVNNSQGSKVREIYDVNNSPVIAFQGIPFAPPGIYTSYCQRHQQKLYIFIAGGTFRAFLPPPGIYAIELQAVANAIHKNYKFLLLVERSGQSQMFLNLGDAINKSDHLSSLERRDQRSFVRPEQLSGSIRKATSASRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TKB8</accession>
    <name>A0AAV4TKB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_504361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011333">
        <property type="protein sequence ID" value="GIY45866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TKB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12707" checksum="4BAA5FF3C8DA1A02" modified="2024-11-27" version="1">MVVIIKVVFKRCNIGIEANRCQRWQHWYIEPQRRPIQASCLIFFPIFSEKFPNMYLTIALCRKRDVGLAITDPMRQLFMIYIRFSQLFYLLMPRSRIASSGQRDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TLA9</accession>
    <name>A0AAV4TLA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_672651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011433">
        <property type="protein sequence ID" value="GIY46529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TLA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14963" checksum="6FA4C62C7A0E4C52" modified="2024-11-27" version="1">MNKNKILRISTGGQFSRFSIHSGGRISSKEFRDWAFMSCTGGGPASRPMFNLMRLQEPGHLIARVCLSGEKDPVGVHAVIIDWRKNSSGMDIAWLIQICWVLFLVLDSVRSLVLMRFPIVQMWKRIIAKVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS79</accession>
    <name>A0AAV4TS79_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_36308_1</name>
        <name evidence="1" type="ORF">CEXT_284691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011678">
        <property type="protein sequence ID" value="GIY48172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS79"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008164">
        <property type="entry name" value="XGLTT_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01744">
        <property type="entry name" value="GLTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY48172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="17566" checksum="D4601FE5766E66B5" modified="2024-11-27" version="1">MGKSFAFEANSSTHPKMFAKIVVFCAALAAAHASLVGPLELGAPVLAAGPLGLGLGKGLIAAPAVATVSSQRTAINHVAPAAPIGAAVANGLVGNGLIGNGLIANGLVGNGLIANGLVGNGLIANGLVANRVIGNGILANGVIAGNGILANGLVAGHGIAGAPLVIGSGLLGAPVGLGLGLGLGKAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUU1</accession>
    <name>A0AAV4TUU1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Catenin alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">alpha-Cat</name>
        <name evidence="9" type="ORF">CEXT_348481</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the vinculin/alpha-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011940">
        <property type="protein sequence ID" value="GIY50108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUU1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.230:FF:000007">
        <property type="entry name" value="Catenin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.230:FF:000008">
        <property type="entry name" value="Catenin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.230:FF:000011">
        <property type="entry name" value="Catenin alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.230">
        <property type="entry name" value="Alpha-catenin/vinculin-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036723">
        <property type="entry name" value="Alpha-catenin/vinculin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001033">
        <property type="entry name" value="Alpha_catenin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006077">
        <property type="entry name" value="Vinculin/catenin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18914">
        <property type="entry name" value="ALPHA CATENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18914:SF9">
        <property type="entry name" value="CATENIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01044">
        <property type="entry name" value="Vinculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00805">
        <property type="entry name" value="ALPHACATENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47220">
        <property type="entry name" value="alpha-catenin/vinculin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="675"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="906"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="906"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="918"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY50108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="944" mass="105434" checksum="68F919A9A172888A" modified="2024-11-27" version="1">MPNTSKDFEFPYGGRGFKRKGEDINLTSVNLKWDPKNLEIRTRTVEKTLEPLVIQVTTLVNTKGPSKKKKGRSKRAHILVAAVEKATENFITKGEEIARENPDIQPEMLLAVDEVRKTGEVMSKSSREFAEDPCSSVKRGTMVRAARNLLCAVTRLLILADMVDVHRLLKSLRSVEDDLDKVKNASSQSELMKSFQDFGKNTAELIQQAAKRQAELKDPRLRDDLAAARAVLKKNSMMLLTASKFFSFEKQAIIKTYLSGFVRHPELSAAKENRDYIFRQVCEAVNTISDVAQGKSTSGALGQPPYDGPGELAAALDEFDERIIIDPLMYNEVRTRPALEERLESIISGAALMADSSCTRDERRERIVAECNAVRQALQDLLSEYMSNAGRKDMSDPLDKAVDHMTRKTKDLRRQLRKAVVDHVSDSFLETNVPLLVLIEAAKNGNEREVEQYSQVFTEHANKLVEVANLACSMSNNEDGVKMVRFAAAQISNLCPQVINAARILAARPRSKVAQENMDAFKEAWENQVRILTEAVDDITTIDDFLAVSENHILEDVNKCVLALQEGDADTLDRTAGAIRGRSARVCNVVAAEMDNYEPGIYTEGVLKAVAILKDQVMPNFASRVEIAVEALSTNPQKEVDENEFIDASRLVYDGVRDIRRAVLMNRTAEELDSETEIEFEANTSETKSKSSAHTDFDEYPEISGINNTRDAYRYISEEDKQKIAAQVENFRTEKSKFDREVAKWDDTGNDVIVLAKQMCMIMMEMTDFTRGKGPLKTTMDVINAAKKISEYGTKLDKLARQIADQCPESSTKKDLLAYLQRIALYCHQLNITSKVKADVQNISGSLIVSGLDSATSLIQAAKNLMNAVVLTVKASYVASTKYPRSVQVASPIVVWKMKAPEKKPLVRREKPEEVRAKVRKGSQKKHIAPIKALSEFQSPAESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4H4</accession>
    <name>A0AAV4U4H4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inositol polyphosphate 1-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">INPP1</name>
        <name evidence="1" type="ORF">CEXT_512671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012268">
        <property type="protein sequence ID" value="GIY52645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4H4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16904" checksum="0369DF173F5CB5A0" modified="2024-11-27" version="1">MASEPILLSDLLQCLVECSEKAARIAQIFRNEDDLFQLLVEEKSDTEKNKRFVQDFKTLADVLVQETIQRDVGKQFPSLGSHICGEEQNSFQNSLGESIRVELTDSEDETAALLSQVLDGRDHVAKLLASVVHSNDSNCGSVRPPVLYLQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UVN1</accession>
    <name>A0AAV4UVN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_157451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013504">
        <property type="protein sequence ID" value="GIY61713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UVN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12029" checksum="3FED7B9694CE0B5B" modified="2024-11-27" version="1">MLGKKFNERNQIKTSMSITEWTSYICWSKSQVKGGRNRDRSANDFLTVLRKCGTLTGRRRWDRSRFSHSDARNAAATVGSHVMVLFFPLPICTLLDLLTLSAIYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V767</accession>
    <name>A0AAV4V767_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_798021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014042">
        <property type="protein sequence ID" value="GIY65874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V767"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13972" checksum="6A2DAA036BC811B1" modified="2024-11-27" version="1">MNTPPVEEENDTFGTIVSLIILSYSKSFFSTDPFSYSQDHSTSSFIHHFLGPSGYSCHDQTGFFFALFVYHPSYGDCDWKSMYILKSIKRDIKCDLRNKGVGCPSGRATTTHVRSEIVLEEVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VDY3</accession>
    <name>A0AAV4VDY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional adapter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TADA3</name>
        <name evidence="8" type="ORF">CEXT_268551</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014360">
        <property type="protein sequence ID" value="GIY68303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VDY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019340">
        <property type="entry name" value="Histone_AcTrfase_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10198">
        <property type="entry name" value="Ada3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY68303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="324" mass="37681" checksum="F84D7F38891836D1" modified="2024-11-27" version="1">MSTDSVEKKSSDERPPKKGKESSSKASASNHHKFIMPPLLDPHQEIPKPPKNDAPSRFWSHIEPFAADITQDIIKTVERWINPEETYENLQNIPEKGEHYSKVWPIEDLTEEIIEGSKSVENAKGLFSNSAQDTAEIERILKLGERKRTSTTVDDSECTLLDKLVYSLVGEKFMIQIDDTMNEFYNDDLLQEEKHCTVDSADESIEKRLYKDFIEAGVLESDTEESEDEKDEVYEELQELQRAFIPLNKYNIIKKKSLLAMAKARMGQQEIKKKLLEHDAKIMELYRMVSNARKNKTMNKKLEDQVKRTQRERKKLIRKLMEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFS6</accession>
    <name>A0AAV4VFS6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_544141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014504">
        <property type="protein sequence ID" value="GIY69216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15506" checksum="A52690CA9330DA92" modified="2024-11-27" version="1">MGSLLLQNDDGVVGDPCQGKYGNIPNPEVPSNSTPLNRIAVTEDEKTCDTDTCTCVYPADSCSEYYRCENGVAYKEKCPEGLLLNQENSPAIMPKMLNVGPLCSKGIISVMKTHLMVKHGGRGLQHYTYLDVIIVYRKQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VQ17</accession>
    <name>A0AAV4VQ17_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_782051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014951">
        <property type="protein sequence ID" value="GIY72487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VQ17"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="165" mass="18437" checksum="190FADCBFBDA46BC" modified="2024-11-27" version="1">MAACGDKFSALSSKGRQPLHALNPLLLEGGKNQDKVLSSLFQLTLLQSSSAVITSQACEGIYVKTPVDEIKDKRNVSNQRDNQLLSFEHRIKTRFISQLLSHPSLKTITDRIHLLCSKNRRNVSNQGDNQPHLIKTIVIRTSKSRLDSNQGDNPQLACLIHLSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6Q0</accession>
    <name>A0AAV4W6Q0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_161061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015755">
        <property type="protein sequence ID" value="GIY78417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6Q0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9063" checksum="952144A6574F2A7F" modified="2024-11-27" version="1">MMQACGEYHQNFQSKSTTTLCKSGRIPKRYRLRILNMLLVEVDDNYQVYPPETYSPGLVLDIDLDTNTCSSEFPDLGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WB36</accession>
    <name>A0AAV4WB36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_43801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015955">
        <property type="protein sequence ID" value="GIY80046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WB36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="24533" checksum="2C100E428DE99712" modified="2024-11-27" version="1">MVLENSPTVTTSMKRLMENSFTVTTIMKRVLQNSYKVKTCMKRVLETSSTVNIIKMVLENSPHCYDYAFSTIIRNHKGLFFQFNGIRFILQPGAFVRSLTPNIVSRHRPGGNRPKRRRKKSQVFPETKTGVQGDEQLDSFSYVQFNGIRFILQPGAFVRSLTPNIVSRHRPGGNRPKRRRKKITGISRDKDGVQGDEQWDSFSYDQVETDTCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WG21</accession>
    <name>A0AAV4WG21_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_460241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016050">
        <property type="protein sequence ID" value="GIY80764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WG21"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY80764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14206" checksum="44516FE7A181CE16" modified="2024-11-27" version="1">MCKQNTRQLSHVIFCATHGLYEPISYTGPHFLHSLRRLQKKKKKEKKKCRRTFTTCGEGGRDGAHARCAGPSTRINSPRRSLLNQRESQAVETSPDFLPGATGTVDCNFICHCRQKREDNLFANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHS9</accession>
    <name>A0AAV4WHS9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_818_1</name>
        <name evidence="3" type="ORF">CEXT_779641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016173">
        <property type="protein sequence ID" value="GIY81838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHS9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY81838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="587" mass="67213" checksum="633D5A071416D1C6" modified="2024-11-27" version="1">MKIYQKKDMSQQEKTALVHLQRRHTLMEGTCEVDPGKNLRRSRTNSLDNILENNLLQDIEASTVEEHELNKKMRKLSRIPTVVITESELSSSSLYKNRKAKINSDDESADEPEPNMPTVDAENPEPRYLNDPNLKPVPVQTAHRPEKVSSCCCYFSVAVAICLVSLGIIIAIGGIVYMELFSAFKEKPETTPIIDINKDDLMNINEMLYELNAKNVLGKNEEIKMEALPIENKFKKSETLTHFVEEISTVESLPIENKFKKSETFTHFVEEISTVESLSSSEKPIVFDNKIVYEPLNDKEKPNNTNVDGQSTKNERLNTNEFEIFLSNLRAVAGRLQEKVSDKSSDRNLHSESNQNLEHTEETHLEDEVTPKNFRDPNLAVESLQETNENLIESDKFNSEPMHVLNENWNNQSLVSEENFETGNDKDHELNLDASKKLLQDSSETDLHTEHSVDLNSSAFHEYLNKDTEHNEQEFNLNDSDHTQLVFIRPVVESKAVPVPLEFLRRIGFDMKNVSLHQPLSPQDMDIKFSLAEALKYLKSLDVDNKLPTSREKSDVPIINTKKEDESKPNVEAEQVKYLDILRERGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQA9</accession>
    <name>A0AAV4WQA9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3',5'-cyclic-GMP phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Pde11</name>
        <name evidence="7" type="ORF">CEXT_409601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.35" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01016420">
        <property type="protein sequence ID" value="GIY83733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047555">
        <property type="term" value="F:3',5'-cyclic-GMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="6">
        <location>
            <begin position="239"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY83733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="316" mass="36045" checksum="AC7AC40DA602CC3A" modified="2024-11-27" version="1">MGYTVLLFSSCIHDHKRLEIADLHWRVVVCCFLPTTCRGTRSYRTETDISLVHISNQNEPLEKEDLFNSLADRRTEYKTDNMLSIPILDKDGEVVGVAHIIKKCQNGKETSVKGDEKVLLDLIRMICEEQGTVAQIIPRIMILAQSFLPVERCQVLLLSENTQTLNIPDVHMDDRFDPSVSENSNFRHHSILCMPIRNASKNIVGVCQLINKLSGIPFTKADEHIFEVFATLFGLGIQHAQLYERAMKAVAKTKVILEVLSYHATAPLEEAQNCRGLSLRMFVDLDLTQRFGIEYDVLCRWLLSVKNNYRPVAYHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQS2</accession>
    <name>A0AAV4WQS2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_775811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016610">
        <property type="protein sequence ID" value="GIY85047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10832" checksum="497DF775D0D41E8C" modified="2024-11-27" version="1">MICFDESFNRISNRLQMNIAIRLLDGSLGFDGSSRKTKYQQDIGISLFLKNAATSVRLMNFKKNFAQRLLKDKSNFDGWPKCKLGFPRSVNICY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WUF9</accession>
    <name>A0AAV4WUF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Follistatin-related protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Fstl5_2</name>
        <name evidence="4" type="ORF">CEXT_374361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016814">
        <property type="protein sequence ID" value="GIY86560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WUF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF32">
        <property type="entry name" value="MAM DOMAIN CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="10"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY86560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14464" checksum="3FC6670021F783D9" modified="2024-11-27" version="1">MWMLTIAALPEVHVVPKLQSRAPGELAEMECHVIGVPQPRVYWLKNDEELKMGSEKYTIIGNSTALVVGKITYSDTGAYMCVATNPAGTTRDISSLVVQDQPARSKDKEFCFILKIVACCITLVKGRVKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WYM6</accession>
    <name>A0AAV4WYM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_809781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016934">
        <property type="protein sequence ID" value="GIY87383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WYM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8065" checksum="676F91A30DB56F6D" modified="2024-11-27" version="1">MSASTKKGEQLKIFPANSDIHRAITKYLTDGKIEFYVITPKNQRPLKAVLKASLSAIPLMRLPLDLLNLVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1F0</accession>
    <name>A0AAV4X1F0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glutamate receptor ionotropic, NMDA 2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GRIN2B</name>
        <name evidence="13" type="ORF">CEXT_365721</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017144">
        <property type="protein sequence ID" value="GIY89031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1F0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="12">
        <location>
            <begin position="6"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY89031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="11820" checksum="7FE7C2C5CD196026" modified="2024-11-27" version="1">MVFFEANGTWNGLIAEILQNKADLIVTSIKINSDRQTVVDFTVPFLETGIAIVVAKRTEPFDTVSWLMILLVSIQGAALAIFLFEWLSPFGYDMKMVPPRGRWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1G9</accession>
    <name>A0AAV4X1G9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_569351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017089">
        <property type="protein sequence ID" value="GIY88661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1G9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="62" mass="7020" checksum="E803121E427C2F14" modified="2024-11-27" version="1" fragment="single">EVPFCVALCVLQEEAAPQPLSAARFDHRKKLLVLILKPLLDLLARILTLEEQLLSDSMAIWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X974</accession>
    <name>A0AAV4X974_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_689631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017327">
        <property type="protein sequence ID" value="GIY90525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X974"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7497" checksum="9A6512626117EF11" modified="2024-11-27" version="1" fragment="single">MCIVPEWSGIVELFGKAHCIMQTWLHDPACDVELSPSSRPEGKKRSCDRQTVHLNNLVTAKTRFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X9K8</accession>
    <name>A0AAV4X9K8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_238561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000075">
        <property type="protein sequence ID" value="GIY91956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X9K8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12447" checksum="EE578B227D166205" modified="2024-11-27" version="1">MSSYLMGSLMSQNFTGSRTCVGNVVNMKPNVYSQYHTDNFEGEDMSYSQISPFLPAANFINQSLTTKDLNSDRFPKLENLTDCHKKFPIIDQNSDLVDSLIVAESIALIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XA51</accession>
    <name>A0AAV4XA51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_795401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017429">
        <property type="protein sequence ID" value="GIY91543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XA51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10750" checksum="6CFCE4C95C7EB645" modified="2024-11-27" version="1">MFLFSFGYKKKKKKTSSDRTNGNCQETEVDQQLPELLHCFHTKLMATETNDAPVSRWKTIPKKIGLSPFPANNTHVFLDMFLKILDKFLREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFF0</accession>
    <name>A0AAV4XFF0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inhibin beta chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Actbeta_2</name>
        <name evidence="1" type="ORF">CEXT_475741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000329">
        <property type="protein sequence ID" value="GIY93937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFF0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10798" checksum="3FDD10FC71AEED35" modified="2024-11-27" version="1">MAYHFEQILSQSLNGHFLLDFYPHEHLNSKLRVTAATLWIQLRYSPSLPVEGRAQLRNKHVTLYAFRVGNSTEQLSHVTSYITRVRLMLDGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFS3</accession>
    <name>A0AAV4XFS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_722271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017597">
        <property type="protein sequence ID" value="GIY92894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="138" mass="16310" checksum="77CFE9532188B020" modified="2024-11-27" version="1">MSGSMASSQLPAMDRSHPSRFIRPTCSFFFLDPPFRNICSEFGGYFERRPLLCRLRVTWWSFYLRRVWMENWMDWIMVNWTLRGDWAGMMAYSLGDQKPMVLPLGCFLLNPDNKEGCLGRGYLMLVEGFMVRERKAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGG0</accession>
    <name>A0AAV4XGG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_79841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017595">
        <property type="protein sequence ID" value="GIY92869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13361" checksum="862605CEE684E34A" modified="2024-11-27" version="1">MLLGRKGTISELRSTDFASEKERLQESFPTFCSSLTHQSEESARSEEGEAKQSDRGSIVRMTSSGFSSDLSDWLWNGIIGLISFEEILADQFKEIQTDSNLGQLVVGKDYAEPFVKTCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIU7</accession>
    <name>A0AAV4XIU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_369151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000386">
        <property type="protein sequence ID" value="GIY94373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13803" checksum="0C8C7F2EEBEE4801" modified="2024-11-27" version="1">MWNFPKYLFPCLLCGNVVIQILWLTFISNSKDYWAVLVVQFLQLWICICVFRSRARLRLLTKELYRISKCCIFTQTEKENVEDLHLAVLFISDLHDCTLRSDVCQFWDDSSRTAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJW8</accession>
    <name>A0AAV4XJW8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Ddx18</name>
        <name evidence="8" type="ORF">CEXT_170611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="BPLR01017743">
        <property type="protein sequence ID" value="GIY94099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="10"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY94099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="25475" checksum="7B10D4979C3F69FB" modified="2024-11-27" version="1">MLFSATFSNKIKDLAQIAVHKTALYMGLEVPEKATVEGLSEGFLSIVFMANKKQNIRNREYRHFCRAEKGILLCTDVGARGLDIPRVDWVIQYDPPNDPKDYIHRVGRTARGENNTGQALLILRQEELDFLKYLYNAKIVLKEIDYQWDKVLEVFPNVQNEVEEIVTSNYHFKFEGKLAYKAYFCAYQSYRLKKVFNLDNLDPAAVAKSFCFPYVPKVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQP2</accession>
    <name>A0AAV4XQP2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_163801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018053">
        <property type="protein sequence ID" value="GIY96485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQP2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9942" checksum="ADB218095C4ACC7F" modified="2024-11-27" version="1">MGRRRQHRCRTIRRWRQQKRRWQQRKSHEAVVDDGAAARDDGSRSHSNRRRRQQKKTMTAVGNVGSRENHMMQCYMMVAEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUN4</accession>
    <name>A0AAV4XUN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Endoplasmic reticulum-Golgi intermediate compartment protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Ergic2</name>
        <name evidence="9" type="ORF">CEXT_207631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018295">
        <property type="protein sequence ID" value="GIY98454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF30">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="10"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="165"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY98454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="376" mass="42829" checksum="86C123A9C20553B1" modified="2024-11-27" version="1">MLRRRLKHVEELDIFPKVQEEYTQPTTSGGTVSILSFIVIIILVYTEISYYSSSQLKFEYSVDHDFDSKLKINVDLTVAMSCSKVGADILDVTNQNAQSFGQLEEELTHFELSPPQKIQWETMQRINLYIREEYHAIQDLIWRDGYSNILKGLPTSKNEPVGVPDACRLRGSLIVNKVSGNFHITAGKHIPHPAGHAHISAFLKDSDYNFSHRIERFSFGEPTAGVFDPLEGDEKIAPDNFYMYQYYIKVVPTEIVHNNRKQSTYQYSVTEQARPIDHQIGSHGVPGIYFKYDMSYVKVKVTVEKHSIWRFLVRLCGIIGGVFATSGIVNGLVKLLINFINKRKKPTISEEPLISMNLAAVVSDKNWKKSNISVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XVI9</accession>
    <name>A0AAV4XVI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_157791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000866">
        <property type="protein sequence ID" value="GIY97979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XVI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13649" checksum="3F245F623E34E6B2" modified="2024-11-27" version="1">MLIHYSSRINSSHTPLISCKCLMTRSTPSQNTFLIQVHSVSQLYARSMSANSTWMRNWPTWHHFMNMDSSSFYEFYSTIVATEIQMMISSLNDLQSIFHRKQITIGRKRYRLCNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1Y9</accession>
    <name>A0AAV4Y1Y9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_370561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018593">
        <property type="protein sequence ID" value="GIZ00874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1Y9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="8835" checksum="65DA3B2A8E143227" modified="2024-11-27" version="1">MKPSLTKNNTSSSAQALIKSAAEGPEWVSPFARPDISGERGCALCRRDPGLQIQVCRAAPCPEIGLSWANLIHGAECFCVSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2E7</accession>
    <name>A0AAV4Y2E7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_595701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001146">
        <property type="protein sequence ID" value="GIZ00337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2E7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16013" checksum="37DB6C34E920D6D6" modified="2024-11-27" version="1">MYECLESLEYLVGVKDFFTFRTKATTPGNHPENSLSLELFIAYYMDYESHDKHETHTHLAEVRNLFTSGSKHLPRRRCKRALKTEEAEGAIACGGAIKSEFERKNAFRAPPVNGARARELRNMSLLSAVIQCVDGCRRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9P3</accession>
    <name>A0AAV4Y9P3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
            <ecNumber evidence="5">3.1.3.48</ecNumber>
            <ecNumber evidence="4">3.1.3.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Inositol polyphosphate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="primary">PTEN</name>
        <name evidence="26" type="ORF">CEXT_13521</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83420"/>
            <dbReference type="ChEBI" id="CHEBI:83423"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:43561"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43552"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83416"/>
            <dbReference type="ChEBI" id="CHEBI:83419"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:43553"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57627"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:77144"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77155"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57895"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:77156"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:20630"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:10685"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:25017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="EC" id="3.1.3.67"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:25018"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Neuron projection</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTEN phosphatase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EC" id="3.1.3.48" evidence="5"/>
    <dbReference type="EC" id="3.1.3.67" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01001692">
        <property type="protein sequence ID" value="GIZ04127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9P3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043491">
        <property type="term" value="P:phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051896">
        <property type="term" value="P:regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14509">
        <property type="entry name" value="PTP_PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000029">
        <property type="entry name" value="Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045101">
        <property type="entry name" value="PTP_PTEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF81">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10409">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22785">
        <property type="entry name" value="Tc-R-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01301">
        <property type="entry name" value="PTPlike_phytase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="24">
        <location>
            <begin position="15"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="23">
        <location>
            <begin position="103"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="C2 tensin-type" evidence="25">
        <location>
            <begin position="191"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="363"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00043760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00043762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00051341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="GIZ04127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="406" mass="46960" checksum="841DE5B2E044943C" modified="2024-11-27" version="1">MMAARIKGLVSKKKRRYREDGFDLDLTYICNNIIAMGYPAEKVEGLYRNHIDDVKRFLDSKHDQHYKIYNLCTERNYDTSKFHQRVAQYPFDDHNPPSLELIKPFCDDVDDWLSKDENNVAVIHCKAGKGRTGVMICAYLLHKRIHATSEEALKYYGNARTHNQKGVTIPSQRRYVDYYAELVRNNLIYTPVTLILRSIIMEPVPTFNGGTCSPFFVVYQLKTKLYTSPVLEVKRNRSSYLLNFLKLCQFVEISRLNFAIDLNLEKRRKCFFSGLIHFFYSVRKEKDTITSYHFPSSPHAEKNRRSVIQHEEYGKGPVLILYKNDLDKATKDKTNKLFSRDFKVTIGFTSVNDSPNIALDSEYRSSVQGHSDTASSHGETSSDNEMLESETDSDDDDWDGSEATHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YB48</accession>
    <name>A0AAV4YB48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Round spermatid basic protein 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RSBN1L_1</name>
        <name evidence="2" type="ORF">CEXT_359981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001626">
        <property type="protein sequence ID" value="GIZ03596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YB48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="243" mass="28088" checksum="CF04928617E417CF" modified="2024-11-27" version="1">MASGKMSAEDSEKNKCDEKNSDTFYMKSEQDQRNLNVLKSVVLPHHGHLKKRSEHFRNLPGLPAAEDLQRNGNVKVCRIVPTPNGVKTVSSNKCKQMNNTLNNKNNCRSSPVHCQDDILDCENKFTPSDLEPNHSLPVGILSEQSVDDKHKYDHVQETEIQSVKSPLSKAEKYLIEKIDKKPERLRENMSVHHTKKKKHKEKDKRDSHSNHREKHQSKHRDRPKIKSGEKLHKHKLHNSISRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCM4</accession>
    <name>A0AAV4YCM4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_82101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019235">
        <property type="protein sequence ID" value="GIZ05206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCM4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10423" checksum="D6756A896E981E91" modified="2024-11-27" version="1">MTTCDLGVTAFSRNRADLHPGTCRIRGTRAPPLGSAGGPPSSWCKSHRRWLLLKTCKIRFFKHGVCGANKPRAPFTTVIWGRGTCKKHSSSQTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4T7</accession>
    <name>A0AAV4M4T7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_663791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001872">
        <property type="protein sequence ID" value="GIX67363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4T7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="9992" checksum="476CED918A7212DD" modified="2024-11-27" version="1" fragment="single">RGRASEFRQLRHTTASWADMCPTIEWEEIFSGQRIDAKITSNGHLPVPKTVEEREADSQESPGAAGGRGEEAGAVRGSTQEQLCGNAAPPQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4U4</accession>
    <name>A0AAV4M4U4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_446971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019377">
        <property type="protein sequence ID" value="GIX67142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4U4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="14189" checksum="6EECC41146E00CF7" modified="2024-11-27" version="1">MIYGRIPPYSQNTIHLFSQHPRRRAKLLRPMDLDQIRKLQIGLCEAELLLLNIPAIDHCKTDHKTMRGQQEADKNLYHTDFKPKVREIPFFVWDFYQDTYNTVACFNNCSLNSVLAYKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MFU8</accession>
    <name>A0AAV4MFU8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TFIID subunit TAF5 NTD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TAF5L_0</name>
        <name evidence="9" type="ORF">CEXT_121851</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat TAF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002207">
        <property type="protein sequence ID" value="GIX71278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MFU8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF7">
        <property type="entry name" value="PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="8">
        <location>
            <begin position="42"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="524"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="608"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="649"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="691"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="382"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX71278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="778" mass="89294" checksum="914E8708D1763372" modified="2024-11-27" version="1">MSQVNDVHETYSISNSDSHSELSTDFLTASKEYGGFIIHFMQAAESIKHQAFNFLYPFYVYIYLILLKEDKLLDCQKFATTFSHIFANSKSFEDLIQDLSKCTTLQDFENHSYFKEFCEHKFTVEMNWKNLKLLKIYLKKDCIVVVDNKNNLQDILEQPGVENNNQTSLEQTGVENNIPTSLEQPCIENNHQTNLLQPDDECNFQTCLDEENTALTYIERETENVRQTYSKSFDDKNYLKTDELSNDERNRQTTFEKLDENYSQAWLVQPERECNSIVEKPCEESSFQVIKLSNDESHPQTSSEQPSEKNLQTGLEQSDDEISLQSSLEPSDDESNPEIITLSSDESNTKIYFEQPNEENNLQTSITQSNDKNSFQINSEKSYDESNLQTSLEQSYDENNSQTNLEQSYDESNSQTSLEQSIDETNLQHEDMSDCVYDGKLKKPASYLYTISCRRQNIHCVDINKNNTLLACGFKNYNIHVWNLDPNVLKSEEAENESKLYRTDLDSSKEGFSSNLSFGSSHKFKGHYGSVSGLAYTPFDSVLLSCSKDATVRVWSIKDFKSLHVYSDDDYPIWDITACDYYAYFLTGSMNHTASLWSFERSTPLRIFLGHSFGVKCVRFHPNCKFIATASAKTLHLWSMQNGQSLREFSGHEACINCVAFSPNGKLVASADDRGCIKIWDVGSGQLFSETKAHSNEISSISFDKSCSLIASAGYDNLLKVWDVKYLYQNTNEREEEKSALVDCHFRDSLIHYVNFNRNNPKEKHHKDMLLCVAALQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHU3</accession>
    <name>A0AAV4MHU3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutaredoxin-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">grxA</name>
        <name evidence="12" type="ORF">CEXT_39741</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer; active form. Homodimer; inactive form. The homodimer is probably linked by 1 2Fe-2S cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019757">
        <property type="protein sequence ID" value="GIX71478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000026">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0318">Glutathionylation</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="11">
        <location>
            <begin position="23"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX71478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="11855" checksum="C1235F6726A6680F" modified="2024-11-27" version="1">MAAAQIDAKLLQEIEDYVKINKVMIFSKSRCPYCHTVKELLKSLGVDYFALELDTTEGGSQLQRAMGKKVGRTSVPQVFINEEHIGGCDDTLAAHESGKLQTLLKAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJG1</accession>
    <name>A0AAV4MJG1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_209141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019702">
        <property type="protein sequence ID" value="GIX70934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJG1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11548" checksum="DE0950AF041BCBE7" modified="2024-11-27" version="1">MGNNNYNFLKQTTQKEISDIHRCYSNSKSITSISSKKQLGRETKGADLRSLSKPLHSKKGKPSKQRGYTKEFPQKNFYPVKSDCWHPVPSSLAAHALPLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MP63</accession>
    <name>A0AAV4MP63_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SEPTIN9</name>
        <name evidence="6" type="ORF">CEXT_280701</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020038">
        <property type="protein sequence ID" value="GIX74170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MP63"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:004705">
        <property type="entry name" value="Cell division protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="104"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX74170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="406" mass="46399" checksum="0DD949081F6789A7" modified="2024-11-27" version="1">MPDISEGQLPGSRHGRKRLHRLSECDFRGEEGARHRPQQPRKGKNSQKAEILAGRGQLSVNAFITVMADTLTETTQWGNLKTDVSGYVGIDTLQEQIRKKVLKKGFEFNIIVVGRSGLGKSTLINTLFKASVSRRTCVKVEGDENGLYKIPKTTEVKSVSHVLEEKGVRLRLTVTDTPGFGDHINNENCWLPILDYINQQYEKYLNEEQSIARKKYIPDTRVHCCLYFIPPTGHSLTPLDAEFMKRLDKIVNIVPVIAKADTLTVEERIAFKQRIKHDLEKNGINIYPINDLEEEPEDVIANNKIREMIPFAVVGSNVQHQINGRTIYGRKTQWGTVEVENRAHCEFPDLRDMLIRTHMQDLVDVTRLVHYENFRHQKLRSHDHRHLNGGLNGQVVDIENLNESSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MPT5</accession>
    <name>A0AAV4MPT5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small EDRK-rich factor-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_432891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002446">
        <property type="protein sequence ID" value="GIX73835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MPT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX73835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10642" checksum="93970D279F197A08" modified="2024-11-27" version="1">MEWNTTLAVRKEKEKKKGGEKKINPPAQRKADQKTRDQLLNQKHPPKRKPSRACRMSSHLMDPLPVAHWRRKRRHLTFLSLEPLSLLRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRX2</accession>
    <name>A0AAV4MRX2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase FE4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ESTF</name>
        <name evidence="4" type="ORF">CEXT_25091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002560">
        <property type="protein sequence ID" value="GIX75107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRX2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043977461" evidence="2">
        <location>
            <begin position="26"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="31"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX75107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9370" checksum="F39C8DE84525D24E" modified="2024-11-27" version="1">MFSAHLVRFFFIFIVSLNTLCEVSSQEYGTTLTLKQGLVIGRILKTSNGRDFYAFRGIPYATPPIGLLRFKEPLMFPGWLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MRY3</accession>
    <name>A0AAV4MRY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophos domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_159201_1</name>
        <name evidence="3" type="ORF">CEXT_480841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020143">
        <property type="protein sequence ID" value="GIX75175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MRY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00144">
        <property type="entry name" value="MPP_PPP_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050126">
        <property type="entry name" value="Ap4A_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850:SF4">
        <property type="entry name" value="ZINC-DEPENDENT ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="75"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX75175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="34341" checksum="8A03E67CD82C0D05" modified="2024-11-27" version="1">MIDIKEFCLKILRIWKNFLFKGMHLIVFIVGVLFQFPLIVHTMICQPFSIYDKYPPRVQHSVLNPTFLENYTELFVIGDVHGCYDELQLLLKKANATSDDVLKIFVGDLLRKGPKNLEVLHYIRNCESCISVRGNNDQKCLLKVYFSHASNNYKLKRSDKWMKKLSPADLEYLEELPYSISIPSLDSVIVHGGLLPGVPLEKQRPWTMMNLRDITPDSDCPGGFRANPKQFKGHPWASKWRGPQHVYFGHDNKRKLQLYPFATGIDTSCYRGNYLTGLFISGNRSGTFVTQNALDKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWM5</accession>
    <name>A0AAV4MWM5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PR domain zinc finger protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">CEXT_770011</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002688">
        <property type="protein sequence ID" value="GIX76688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001316">
        <property type="entry name" value="PR domain zinc finger protein 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24381:SF450">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24381">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21549">
        <property type="entry name" value="PRDM2_PR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="8">
        <location>
            <begin position="289"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="523"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="551"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="598"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="657"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="698"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="728"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="757"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="785"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="813"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="841"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="899"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="944"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1005"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="859"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1129"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="875"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1147"/>
            <end position="1158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX76688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1214" mass="137788" checksum="C7308ED6034455AA" modified="2024-11-27" version="1">MESISNRTSSPYVVSSNSLIDSNNIAVYEDHASSLPSTSVGQCIPLNVYAIDRGVALVTSSRDSPESGLNETVEFETSHASSHQSVQNYVSSSVDLVHSHQLDHSMHCTVDSTVGPKLHHGDESIVDSSDGYSEHLESPDNVLHTTTGGDYVMSDVNSCDGNNTNEVTSMLNNNSNLEANEALSASNHNFSNNQYELQSCATVSSATHPDSTRSPLGISENSANYSLSQTSLTSSADVIQSRPRRDLRTNRFWCEDCGAFFDRECSRHRVQLIFDKPVLSRAWASLPAQYLYVNKISVNNETGETVYGVFAKKTIPKRTQFGPIEGVLVKREDPPSDHFILVLEHEENIVLYLDTSDESASNWMRFVRPAHSHKEQNLVLVQQGQSLFFNTTRVINPKTELRVWYSTAYAEKWGLPVLEPNEEEKKALEEQENAWPCFECNQRFLTSVDLQKHLNQHDEENNVTGVSRTRNKARARARFAKKSHVTRFKGTVVENAIDGENSLRKARGKQPKKYKIPNKQEDYKCDICCKTFQRNYSLQRHLIMHTGEKKFKCPICDIKFSHVYNRNRHVRRHKHDNEKKQLVKPVKTLFKKKQGAEWVCIHCGLTFDNSRVLNLHTLTHAAENVEYSEEHQYLESTVVEEGFEASNESKLGSEEIHKCPECTQEFLSRKDLIEHASVHGKVSKQRCYKGIINPLKPYKCNLCYKSFASDERLIKHYLVHGSEDSKPLQCDICYKRFLNNSALACHIKVHSDERKFYECPICKMEFDQIVALKEHVHVHCVNGVYSCPNCNKVFDEYNQIRKHIRAFHSNRRYPCEKCDKVFPRPDKLKLHMLRHSDHREFLCAHCGKQFKRKDKLKEHTKRMHAPDREAKVNAKNSKSSGSKKFVPKVSPQDYHRFIYKCHTCLLGFKRRGMLVNHLAKRHPDIRPETVPELNLPILKTTRDYYCQYCEKVYKSSSKRKAHILKNHPGSELPMSNRRKGGVPDIPGVPNPTFSQTVGSITTHPHHCNWCHKQYASKAKLLQHQRKKHVDMLALSYVANNTKVEPACDQGTQVTGEIVIESGIQEPSAVLIDSAKQRVHYLDKNAMVVASHDGLPTADLLTQAMSELTQNFEYRSGSEFILTRLSQSTPATLVNPSPSTTPIPDAPSPSAVPTSSPSVLDASIGTPLDPLQLNQFIAQYQQQQQLNPQQLVVLTSVTRSWPTGVTTTLSNYPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXQ3</accession>
    <name>A0AAV4MXQ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein heavy chain, cytoplasmic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dhc64C</name>
        <name evidence="2" type="ORF">CEXT_808041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020310">
        <property type="protein sequence ID" value="GIX77251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXQ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="458" mass="53412" checksum="18753997B7ACB0B7" modified="2024-11-27" version="1">MKRVEDVLGEKSALVRISEYLWLLLTKLIKQINSILFAISLIESIRSYERTCEKGVSLVWESYKLDPYVQRLAENVFNFQEKNRLTLMFAQLKLCAYSTNVFADILNKIQKAVDDLSLHQYSNLHLWVNKLDEEVEKKLALRLEAGIKAWTKALEGKSQQEADLATDTDTTTAHKLGGDPQIQTLIHEIRITNQVIYVNPSVEEARFNIMQQLFAWENVVLLQTRIQSSRYQIVQFLNLTRNLLRKMPDGAITLEAAYQEIENKIKQMDSYVKRMARYQALWDLQPEALYSKLGENINLWMNTLIEIKKSRTTFDTTEVRKEIGPVIIEYAKSRSDLEQQSIETDSTSDAVTFITYVQSLKKKMKIWDKKVELYREGQRILERQRFQFPNSWLHIDNVEGEWSAFNEIIRRKDSAIQVQVASLQVKIVAEDKAVEARTNDVLNEWEKAKPVEVNLHFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2U1</accession>
    <name>A0AAV4N2U1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA-directed RNA polymerase I subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">polr1d</name>
        <name evidence="9" type="ORF">CEXT_323061</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020429">
        <property type="protein sequence ID" value="GIX78600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2U1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerases I and III subunit RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="8">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX78600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13830" checksum="5ACE2EF3F7381FFE" modified="2024-11-27" version="1">MEEVTRRLEVLSSSEEDITCRTFIFRDEDHTLGNALRYIISQNPDVEYCGYSVPHPSIHDINFRIQTKGAPATDVLRKGLEDLQKLCEHMKSTFQNEWENYKNEKMDEIEQMISDMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4L3</accession>
    <name>A0AAV4N4L3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_412701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020488">
        <property type="protein sequence ID" value="GIX79381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4L3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="144" mass="15767" checksum="FDEBFDB5B2BA7FB1" modified="2024-11-27" version="1">MSFRYPSDQFTNPSDEKIAKQQFLSTTTIEILNGPIKKTVCYPSDQFTGPSGRSRLQEKEGGKISEATINARARRLKRGKVIYFEGGFLCPSLAPAHCIVDCCQELSAKLKCLTPLSYSRTHGSSGLAEEFPYHEKGGEGGSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8E4</accession>
    <name>A0AAV4N8E4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_65001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020524">
        <property type="protein sequence ID" value="GIX79709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8E4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX79709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8582" checksum="8EA8C616C73C2D82" modified="2024-11-27" version="1">MVRLAGFPRTAIISIVNGSPTDPGRGGARSVRGGSPPGDPSARPLYLNGEPDPPGMKTRTWKMSRGSGSCSFRRTRTRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NA35</accession>
    <name>A0AAV4NA35_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_578921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003045">
        <property type="protein sequence ID" value="GIX80561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NA35"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9231" checksum="8C12B9C7606BFDB2" modified="2024-11-27" version="1">MNNLPFNKEDKRNEKQLHDKKAMLHCTTSKTQPFTYRGVKNTANSVQPYPCYTAPKLQQLQKEKLEGAQHWLFLRPGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NEY2</accession>
    <name>A0AAV4NEY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histamine-activated chloride channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSH_0364</name>
        <name evidence="3" type="ORF">CEXT_640111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020828">
        <property type="protein sequence ID" value="GIX83048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NEY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19049">
        <property type="entry name" value="LGIC_TM_anion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="2">
        <location>
            <begin position="12"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX83048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14886" checksum="B537F05E1038ABA0" modified="2024-11-27" version="1">MYSDCIHVHADFWMPVDAVPGRVTLGVTSLLTMITKQYQAALPSVSYVVALNVFLSVCIAFVFSSLLEYALVIALRSHQNRHIPEPNKGRAVDAETHPVCWDKLFSYFEDTDVIKIDRYCRILFPALFVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNS8</accession>
    <name>A0AAV4NNS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_542371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003511">
        <property type="protein sequence ID" value="GIX85376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX85376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11268" checksum="99D6D914C7563383" modified="2024-11-27" version="1">MEEAILAAPEQHLGNRNVLYLLPPSSRTREGKQRVRRCLPWKRTRDINVRTIRIDFFSSSSGLVNCSVVVNCSGLVIMVRFNVASWCNDQFLDLMSHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NNX9</accession>
    <name>A0AAV4NNX9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial cardiolipin hydrolase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial phospholipase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CHLREDRAFT_190403</name>
        <name evidence="8" type="ORF">CEXT_579031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the phospholipase D family. MitoPLD/Zucchini subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003517">
        <property type="protein sequence ID" value="GIX85475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NNX9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016891">
        <property type="term" value="F:RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034587">
        <property type="term" value="P:piRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09171">
        <property type="entry name" value="PLDc_vPLD6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051406">
        <property type="entry name" value="PLD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856">
        <property type="entry name" value="CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856:SF1">
        <property type="entry name" value="MITOCHONDRIAL CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX85475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="21665" checksum="C1710273F4289D06" modified="2024-11-27" version="1">MQHYKYDNSIENFNKVIFFPDPGIVCRRTASGRICKDKKCCAVHEETSLNHLLNVLKFSKQSVDVCVYMITCSILSEALVECHERGIKVRIITEMRNSGEEGEVIGSQIGKLRAIGISVRCRSSSFWMHHKFVVADNEILVNGSFNWTNQAVMGNFENLLITSDDNLVKPYIIEFQRLWNLLEPVFESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUY2</accession>
    <name>A0AAV4NUY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_178131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003689">
        <property type="protein sequence ID" value="GIX87558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="20469" checksum="7BBDF4DBD7CDFF13" modified="2024-11-27" version="1">MHIVCYATLSEELAFAINAISTVRHLNGLEFRIFTYNHLFERLVLPYLDAFQMAFEAVWRRCSAAIEKYCAANWYHKNLDYRRFQHLLECGTKRFRFHLREIKTFQGTLLIYFSVLLCHVGVLMEKRGIDRATYFIPLTLSRFIAQLMYWGPFPDWADFAKTAEKISMKMGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P569</accession>
    <name>A0AAV4P569_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_536961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021564">
        <property type="protein sequence ID" value="GIX91173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P569"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10464" checksum="E4FE7F2E4BFB48A2" modified="2024-11-27" version="1">MATLVVTYPRGSWKRRRIEMAAGISDVMRGHFDFGRYFWNFAEDIESGIFVEDVESGIFVEDIESWNFVEDIESGILWKILKVKFCGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P7I2</accession>
    <name>A0AAV4P7I2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_255946_1</name>
        <name evidence="3" type="ORF">CEXT_606731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004175">
        <property type="protein sequence ID" value="GIX92968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P7I2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX92968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="379" mass="42659" checksum="65BEA8FDEA4E8130" modified="2024-11-27" version="1">MILFHSSELDFAFVRLPFKVCEGLDKGGLAFALSNYIQEEDSKSRLLNRSLIIILFLLMVSVSSIMYINFDDDLYKASLSFCVIRSAVKMFLKPEIVSDSYLSSKVPETIEVDVRMEKLRKLRFQMCPEEIEWKEVDHLLVEKSAAAAASIVRDFTVHHQSSPLIVSKAKEATGMGPETGEKNHDHDDPHWTATQESDESVSSPFQLQQLDDSPRSSQLHIKDVQDMKPDGEESQAQFYELGVMQNTPPDILEPTKQAYFATINNSSSQQVMVNPCLTTFCSGGEIGEQCIINTRKASDQCALVTEGLRTSSYSTFRPPANPPSSTFQSPLKSMKEEDRDKKESATSFLKSSEKQELQNLQVVLKPRRRLSNLPSVRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9Q9</accession>
    <name>A0AAV4P9Q9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Kynurenine--oxoglutarate transaminase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Kyat3</name>
        <name evidence="12" type="ORF">CEXT_3951</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:18121"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29256"/>
            <dbReference type="ChEBI" id="CHEBI:58717"/>
            <dbReference type="EC" id="4.4.1.13"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:18122"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid degradation; L-kynurenine degradation; kynurenate from L-kynurenine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004314">
        <property type="protein sequence ID" value="GIX93940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9Q9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070189">
        <property type="term" value="P:kynurenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000275">
        <property type="entry name" value="kynurenine--oxoglutarate transaminase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000021">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="73"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIX93940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="462" mass="52086" checksum="D6B7A2DFF3891A23" modified="2024-11-27" version="1">MIRYLNRLRTLENKLSRYHKHVSQSVLTGQADISSPYYQNKRNMAYGGPANRLQGMKESVWVEFIQLALDYKPVNLGQGFPDFAAPDHVAKALSEAAVSPNVLLNQYTRGFGHPRLVNALSKLYSQLVGRTINPQKEVLVTCGAYEALYCTILGLVNPGDEVIIIEPFFDCYEPMTRMAGGIPVFIPLRPKKTGAGVSSNDWCLDPEELASKFNKKTKMIIVNTPHNPLGKVFTREELLMIGDLCKKHDVIAVMDEVYEWIVYKGHEHIRMATLPDMWERTITIGSAGKTFSVTGWKLGWAYGPQHLMQPLQLLHQNCVYTCSTPIQEAVAIGFETEIARLGQPGSYWLELAEMLENKRDKMVKFLSEVNMAPVIPDGGYFMIADFSALASKVDISGEQGTKDYQFSKWLSKNKKLQGIPPSAFYCEEDKPLAQNLIRFCFIKEDSTLEKAEKIINDLKKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAL8</accession>
    <name>A0AAV4PAL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_313991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004351">
        <property type="protein sequence ID" value="GIX94240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8949" checksum="007774A253C3A55B" modified="2024-11-27" version="1">MQKDWQVVVREPPWGFRASIAVQTISALLPPLPEKSDAVEWRRKEAHEAVTPIPAGTFKRSPIKGATLLFVREERRGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBG9</accession>
    <name>A0AAV4PBG9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_186061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004412">
        <property type="protein sequence ID" value="GIX94712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBG9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8547" checksum="37DDFCB6B68A01B3" modified="2024-11-27" version="1">MHHNRADCQGFSRIPKWLLATGRYEETGRLLRNIASTNGRGLSPDYVVNLKSALFKSCQDDSQVYHDSDSGSYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PCX7</accession>
    <name>A0AAV4PCX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Probable serine carboxypeptidase CPVL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CPVL</name>
        <name evidence="7" type="ORF">CEXT_606271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004455">
        <property type="protein sequence ID" value="GIX94951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PCX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF472">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CPVL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX94951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="18337" checksum="361A43192DBA2132" modified="2024-11-27" version="1">MGESYGGKYVPSLAYKIHNEGPASKINFKGIAIGNLTFQNGEMAQRNLLLDIMQSVKPEVTVIMNNYKVLFYNGQMDLIVPYPLTMNFLYSVRWKNADAFKKVKRQIWRVNDTDKIAGYVHNVGDFYDVLVRDSGHIVPYDQPKIALDLITRFIKKIPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PGS2</accession>
    <name>A0AAV4PGS2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_126780_1</name>
        <name evidence="3" type="ORF">CEXT_495211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004554">
        <property type="protein sequence ID" value="GIX95715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PGS2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043999902" evidence="2">
        <location>
            <begin position="22"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX95715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="211" mass="24497" checksum="35A77545486A6DD6" modified="2024-11-27" version="1">MKISWNMFFMMMTLLACQCSAFWPTKDDDENDKPSLFKPKLISVFSKPSPDADKNPTLGILPHLGNLLHGGTIGLKLETRPLGLLHDILGHAKKIIPGTLDTIGHPNHEKPPKDLWEQDEEWESEKPKKEENKKWEQQKKPEGPSWEDIGEQPETYNTEVPIEDIIQPRNRPKRFIESKIYHVPLLYRSNGRPYQVKIRSRNDLDEIKEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PQ06</accession>
    <name>A0AAV4PQ06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_114241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004878">
        <property type="protein sequence ID" value="GIX98223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PQ06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13008" checksum="AE3A5BAA9A6F81FA" modified="2024-11-27" version="1">MDDVQSCNSMISSNNNYFKSSKSINELVLRLGQKSFEEIHIICQHRDAKHKIPRSNPFLIQADIKKHINRHDNITNIKFSRQGKLIFSTADPVCAAQILNLEKFKKRPFLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PR42</accession>
    <name>A0AAV4PR42_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_727591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004804">
        <property type="protein sequence ID" value="GIX97647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PR42"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX97647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10848" checksum="EEFF39310831B465" modified="2024-11-27" version="1">MPHSRTLERIHREMHLLAGSHKPDGGGDARLRGTPWPSRLGVGADNSIMKKSDEETNRTALKKRPRKPTLDLKLERLIFIKKQITSDGSRKSGRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXZ2</accession>
    <name>A0AAV4PXZ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_429651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005391">
        <property type="protein sequence ID" value="GIY01942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8422" checksum="78B05F07F9D96A26" modified="2024-11-27" version="1" fragment="single">EGEKGEKVNSYQHQLSFSLASCPFLSNYVLELQSPESLETGDPCQKRIRLTFGEPRILITIRDPKPMGTVIKGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q9L8</accession>
    <name>A0AAV4Q9L8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_579181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005665">
        <property type="protein sequence ID" value="GIY04083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q9L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="226" mass="25282" checksum="09A55EF4C7DEDEC1" modified="2024-11-27" version="1">MNNKPIIYFVTNFPNEYPFRTSSYFPTISSVHCHCDKSRLVLSSSATAAIIYHCFVRIPLLPSSTTASCEYLCCHHLTLLRVTFSAANVSNCCHRFLLLPSSSNNATCAVVVCHCCHHLHCFERISLLPSSNTSSCDFFCCQRFQLLSSSSSAAVVFYSSDFCYHRLSLLLSSTTASWGFLCCHHLPLLRVTFSAVIVFFCCRHLLIVRLVLSSSATAAIIYHCFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA76</accession>
    <name>A0AAV4QA76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_129627_1</name>
        <name evidence="3" type="ORF">CEXT_13901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005915">
        <property type="protein sequence ID" value="GIY06010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001558">
        <property type="term" value="P:regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042357">
        <property type="entry name" value="WFDC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14308">
        <property type="entry name" value="WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14308:SF0">
        <property type="entry name" value="WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043786282" evidence="1">
        <location>
            <begin position="22"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="80"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY06010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="29833" checksum="1B27F807EDB0B6C4" modified="2024-11-27" version="1">MPKCSAPLTVIVYVLHSLTVSRQVDYEKRPIKRNFSPFWREPTWRQDVKSDIYNRCTPFGHLPNDSTEEIKSYLTSILSQNASFWSCPAPKLPLLDEDCKLPACKNSEDCASKNQSCCFNGCIFTCVDRLTPPPVIDWDNEVEAPPLRREGEAVLRCTTSPRPAPSEPVGCPKGYVCKIDDYGDPLERRYNSGICVPDSSADGEHGSDSLHESGLKEKTRKQTVYLPGGCILSEKQYEDMKEFMTRSYVDDCLCIEGSIECKVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QA93</accession>
    <name>A0AAV4QA93_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_112881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005860">
        <property type="protein sequence ID" value="GIY05579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QA93"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY05579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8043" checksum="5ECFDF387C18C5A6" modified="2024-11-27" version="1">MNRHRKFAGRKECLQLEVGKKVACRFRENGITRLCGALSEFQRVGAVSGYDHVKSFTVPPHPLSWGSKGLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHI2</accession>
    <name>A0AAV4QHI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_215881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006124">
        <property type="protein sequence ID" value="GIY07571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14388" checksum="D23BAF0991F96083" modified="2024-11-27" version="1">MAWMGTIYPMEHTGDAVSQVVLDIESGSSLRNNLESLSPPSIWKNTELRELSENEELLSFHRRTIAAEGTDRTINYFELMKIKKQEIRSHWKLPELLPENGPNCSEREEQAFRWVKATLIASQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUE4</accession>
    <name>A0AAV4QUE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_615531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006912">
        <property type="protein sequence ID" value="GIY13273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="15276" checksum="E66DCEEDD98B8239" modified="2024-11-27" version="1">MLESFQSWLFFERFRNHRIKRDNSIKSEEGTKCLYIQHLFQFFNWDNWVLQPYSSHTSVACSVEPAPMCKAQPTSPYGSLVYSYEKYHPMPEDDACSKFWVPHCYPNKMASVRILYVNNEPSRYFVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QXB7</accession>
    <name>A0AAV4QXB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_215531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006869">
        <property type="protein sequence ID" value="GIY12951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QXB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10772" checksum="7272CC1BF5DA2C2B" modified="2024-11-27" version="1">MYPISAFFPVSNSVTIRGGGHSDWADSGFVVNSKQRETLLMSLRQGSLNDHHSVDCHNFNCSNYGNKQYHGSRLQRDNISDNGGDGSELIICYTTFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYJ3</accession>
    <name>A0AAV4QYJ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_581111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007058">
        <property type="protein sequence ID" value="GIY14302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYJ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY14302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12187" checksum="3DBFB6A4B33C0BC7" modified="2024-11-27" version="1">MHRNSFASPFLSSLIEYEPSFLELILSSEVKATEVFTSFKRIQRRVDQLRSMTSYSNLGRISESFITFQKTLCKHCDLPPIAISPMLLTFKLRLWLCLSFLPFSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R5Z1</accession>
    <name>A0AAV4R5Z1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_340241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007540">
        <property type="protein sequence ID" value="GIY17753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R5Z1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9774" checksum="098669891C99BE3A" modified="2024-11-27" version="1">MTMLSEISPRQVTTKQENSMEGQKNKNPESDAQKKNFPLRAGRRGLWVKPVLRVTFRGHVRVRRLRMWRIMGGDRATDNEHSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R810</accession>
    <name>A0AAV4R810_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_647111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007382">
        <property type="protein sequence ID" value="GIY16466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R810"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13296" checksum="7F2C4A27CF6F2CEC" modified="2024-11-27" version="1">MQGYSLKCVLDASWSRFGVDCCSWSRFGVYCCSWSRFGVDCCSWSRFGVDCCSWSRFGVYCCSWSRFGVDCSCWSRFGVYCCSWSRFGVDCCSWSRFGVDCCSWKIGVADLVGSILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8B4</accession>
    <name>A0AAV4R8B4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_256591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007527">
        <property type="protein sequence ID" value="GIY17632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8B4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY17632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9280" checksum="44D7141FA5C0D972" modified="2024-11-27" version="1">MSSPGKPPHLFPEVCSVLPRGQKCSVRPQECWLRLNLLTSGIWQPRKGVGREVKGTHCSRKHLSRGCSEVVGSNYHSGQLEVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFZ7</accession>
    <name>A0AAV4RFZ7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_805471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007745">
        <property type="protein sequence ID" value="GIY19367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12342" checksum="05EA15EBE0599148" modified="2024-11-27" version="1">MFHYDRSLCYEDHYVPLKPDHCVMKTRSLCQTSMLRRPDHYVPLCQTTMLRKPDHYVPLCQTTMFHYARPLCSTMPDHYVKKTRPLYPIIPDHYVPLCQTIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RIM6</accession>
    <name>A0AAV4RIM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">G-protein coupled receptor 83</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Gpr83_1</name>
        <name evidence="12" type="ORF">CEXT_657891</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007870">
        <property type="protein sequence ID" value="GIY20379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RIM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235:SF29">
        <property type="entry name" value="GH23382P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235">
        <property type="entry name" value="NEUROPEPTIDE Y RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY20379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="205" mass="23430" checksum="FB5F8CF0791F78D4" modified="2024-11-27" version="1">MCSFVPLVQVTSVYVSTFTMTCIAVDRYRIISKPLEPRLRSLQTIKMLVLVVILFALCWLPLNTFNLIREFNATAFIQKSVTHSTVFFICHWLAMSSVCYNPFIYCWLNEHFRAGAVNCLPCMKNVRSQPDDSFKSTKISRPNSIPTTFSNADESFQDSSNDSFCSNVVTITSKSDSRKSRSHHQTYDFNMPLRTFSTKTIQASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJZ8</accession>
    <name>A0AAV4RJZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_28281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007939">
        <property type="protein sequence ID" value="GIY20807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10401" checksum="EA103E5FEB02AD77" modified="2024-11-27" version="1">MVFFSSENTLGHRQEAGIESSNQQVLSPQKINGHKYLKGDLKREKEWKLNNLRPSINTTPLLETNSMGLLTTVCLPTPIQAGGCRDIPLLPTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTT5</accession>
    <name>A0AAV4RTT5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_446891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008353">
        <property type="protein sequence ID" value="GIY24114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTT5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9775" checksum="FC7A92C042604630" modified="2024-11-27" version="1">MWSPHGSVNKFSDDEVSSADEADIDEEEDAGNERVKVLVKRKLNHLERTRADDGCTTDNVVTQQTPLCGTISSTSDDTPLIDREVKPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZ07</accession>
    <name>A0AAV4RZ07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_142281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008672">
        <property type="protein sequence ID" value="GIY26339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZ07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13673" checksum="D824448D06C365D6" modified="2024-11-27" version="1">MAQFSCVYVKESKVTAINFGRGGRNMFHHHDGQELVMNKQKKTSILMDSSHTSSREANWTISVPHLFLKSLAVVTDGNHPIGYGERDRGKGCITVRTTQLEEKFPTSFNLKSRVIANFFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S058</accession>
    <name>A0AAV4S058_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_172421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008759">
        <property type="protein sequence ID" value="GIY27007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S058"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="8769" checksum="16779A008570B0F1" modified="2024-11-27" version="1">MSSELVSPLSHGKIAWGAPTKSNQLLLSCLSFGGTAAEDIRIDMNHMWKLCTISGSCQSFCSTKNIQLLPLIVCWAKDGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0I9</accession>
    <name>A0AAV4S0I9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Grh/CP2 DB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_115742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008617">
        <property type="protein sequence ID" value="GIY26045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0I9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007604">
        <property type="entry name" value="CP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040167">
        <property type="entry name" value="TF_CP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037:SF20">
        <property type="entry name" value="PROTEIN GRAINYHEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037">
        <property type="entry name" value="TRANSCRIPTION FACTOR CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51968">
        <property type="entry name" value="GRH_CP2_DB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Grh/CP2 DB" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY26045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13128" checksum="860CB62CFEEBB5A7" modified="2024-11-27" version="1">MNMGAERKTRDEERRAAKRKMTTAGGETAVTFPGRKKLEEMFHLPCDRSEFYSMSDLLKPPILFTPNDDIEKMTSMDLAFYTNTNSLVEDPNGSGLDRRDTDSRESSNAFTPPQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S0P1</accession>
    <name>A0AAV4S0P1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_193311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008791">
        <property type="protein sequence ID" value="GIY27250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S0P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12028" checksum="FB80404A09DDC294" modified="2024-11-27" version="1">MEAIREIPPDFDFIKDLNVSESRNNQPMTDVFCILHFIAISPPKKKEGEREGIIMTWESKEGKCTFIGEEICLFGASPSSFLRRLTGIKKSSKKIELLSLHLLLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SJJ5</accession>
    <name>A0AAV4SJJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_419871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009599">
        <property type="protein sequence ID" value="GIY33159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SJJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8451" checksum="02A74E42FC6C68BB" modified="2024-11-27" version="1">MNHTQPAGTANTTRIELKHKKAKVAGGPFQFESQSHGSPFKSPSSIFLHTFILLKLNTDKSPGRPKYPPLSYFLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SU80</accession>
    <name>A0AAV4SU80_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_208156_1</name>
        <name evidence="8" type="ORF">CEXT_643291</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010244">
        <property type="protein sequence ID" value="GIY37973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SU80"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY37973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="175" mass="20372" checksum="F416229087CC4A34" modified="2024-11-27" version="1">MSLLKNTLSGCRFLVIHRNISLMRVDCAKNVQGSYTSKAKTMGGLDIQKKSLPVESDVKNLVNYCCGTNINKEGEDVKLKEDSEYPDWLWELRLGPPPPLEEMDPNTKEYWEQLFFLQKIRKLRLKKVVGRKKLFVNEGDKIYQLKKIRFRALASKYDPGFDTPPQFDKDGWRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SWS3</accession>
    <name>A0AAV4SWS3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_229101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010107">
        <property type="protein sequence ID" value="GIY36917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SWS3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008255">
        <property type="term" value="F:ecdysis-triggering hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018990">
        <property type="term" value="P:ecdysis, chitin-based cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006825">
        <property type="entry name" value="Eclosion"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04736">
        <property type="entry name" value="Eclosion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043730431" evidence="1">
        <location>
            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="7933" checksum="027A7D3D8973FC29" modified="2024-11-27" version="1">MTIILIAVLLIIVPEPNESGKVSLCIHNCAQCKRTFGPFLKVKDVPSGVSEFKERLCLTVRSLIQLPISLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZX6</accession>
    <name>A0AAV4SZX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_128014_1</name>
        <name evidence="4" type="ORF">CEXT_147511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010260">
        <property type="protein sequence ID" value="GIY38117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY38117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11830" checksum="DAE4274D6A93FC53" modified="2024-11-27" version="1">MGAVGGQPDPDSIKMFVGQIPRHWNESDLINIFEEFGPIYQISVLRDKMTQQSRECMHQFDYSMVACVGTAIHNLGHISQGLVSEDSYLSSISSNEIERFLFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T000</accession>
    <name>A0AAV4T000_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_445671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010327">
        <property type="protein sequence ID" value="GIY38591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T000"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="16529" checksum="C9F6DC0B4C8D156F" modified="2024-11-27" version="1">MDTARTWRQRNLQSSHFFPNGILESNRPLVSLKIFETNTYKIKHLASKFRGNVSNNAKRSQIGSWSLLLRFDGYINHSVIALGDIGEESKIKSCGFVAFDLLSGCAWTFWTPPLIIAVAFQPLLLIMKDFGSRFNFKLCGYRAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T0S9</accession>
    <name>A0AAV4T0S9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">U5 small nuclear ribonucleoprotein 200 kDa helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Snrnp200</name>
        <name evidence="14" type="ORF">CEXT_382571</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010294">
        <property type="protein sequence ID" value="GIY38375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T0S9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18021">
        <property type="entry name" value="DEXHc_Brr2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000004">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000048">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000368">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000004">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000254">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000013">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
        <property type="entry name" value="SEC63 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF5">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="297"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="505"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY38375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1087" mass="124751" checksum="B297C9499B0D5AF8" modified="2024-11-27" version="1">MERVPIPIKESIEEPSAKVNVLLQAYISQLKLEGLALMADMVYITQSADRLMRAIFEIVLHRGWAQLTDKALSLCKMIKRRMWQSMSPLRQFKKIPEEVVKKIEKKNFPWERLYDLGPNEIGELLRMPKLGKTVHKYVHQFPKLELSAHIQPVTRATLRVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKSKFCQDEHIVKFFVPVFEPLPPQYFIRIVSDQWIGSETQLPISFRHLILPEKYPPPTELLDLQPLPVSALRNPFFESLYKDKFPYFNPIQTQVFNSVYNSDDNVFIGAPTGSGKTICAEFAILRLLSQNPEARCVYVTPKEPLAEIIYADWTVKFGNVMNKKVVLLTGETGTDLKLLARGNIIISTPEKWDVLSRRWKQRKNIHNINLFIVDELQLIGGEDGPILEIICSRMRYISSQIDKPLRIVALSSSLANAKDVAQWLGCSQNSTFNFPPNVRPVQLELHIQGFNITHNASRLLAMSKPVYQAITRLSPRKPVIVFVPSRKQSRLTAIDILTYCASEAQPARFLHCTDEDIQPFVDRIVDKTLKETISNGVAYLHEGLNSTDSKIISQLFESGAIQVVVVSRNLCWGLSLAAHLVVIMDTQFYNGKIHTYEDYSITDVLQMVGRANRPAIDEDGKCVLLCQSSKKDFFMKFLYEPLPVESHLDHCLHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGVAHRHLSDHLSELVENTLSDLEQSRCISIEKEMDVSRLNLGMIAAYYYINYTTIELFSMSLNNKTKIRGLLEIISSAAEYECVPIRHREDNLLKQLSTKLPHKLANPKFSDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSDGWLSPALAAMELAQMVTQAMWNKDSYLKQLPHFTSEIIKRCTDNGVDTVFDVMELEDEDRNKLLQLNDAQMADVARFCNRYPNIELSYEVQNKENIKSGETVNVNAQLEREDEVTGPVIAPLFPQRREEGWWVVIGDPKSNSLISIKRLNLQQKAKVKLDFLAPSPGEHTYTLYFMSDSYMGCDQEYRFNIKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T7Q2</accession>
    <name>A0AAV4T7Q2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS_1_like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_127810_1</name>
        <name evidence="8" type="ORF">CEXT_518281</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010884">
        <property type="protein sequence ID" value="GIY42698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T7Q2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF30">
        <property type="entry name" value="SUGAR BABY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="41"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY42698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="176" mass="20229" checksum="5B7F243F4270B978" modified="2024-11-27" version="1">MDPQEKCKKVDVYAISTESIPNKAVDPTKTFWHIDKEMLYFKLHFFLFMGALSMVLPFISVFAKVRLGISASSLASVLMMEQFLFIVTKPILGYLADYFNKLKTIICMLTIFQAIFFFLLLIIPKIKIPQNESAFEISSELINVIMKSESHQYSGNSSKQDGQYFSIKDDFLCVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJ98</accession>
    <name>A0AAV4TJ98_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_338781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011282">
        <property type="protein sequence ID" value="GIY45531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJ98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="18098" checksum="322165E78853B3D3" modified="2024-11-27" version="1">MIQTKETVLFLGRYQDERHDDRIFPTPFSISITSHQSFRANHLFLNVNEHFEQKESIDPLPTLIGKSGGETENRRPPQLSWQRPKRSRGIFPFIDPQELEERFASDRKRKPSQLDFFMRNSHPHYLPEQLISPALKRPLRICRTDMPRWGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TRF1</accession>
    <name>A0AAV4TRF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_716941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011619">
        <property type="protein sequence ID" value="GIY47754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TRF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8548" checksum="473E5EED67D85AAE" modified="2024-11-27" version="1">MQDEEGSIAVGGMQKSHCFEIRVELGEIVTIDCRHTNRKRYLKAFFEDIFHRNLILVRLFLTLENTGSATVIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TUQ1</accession>
    <name>A0AAV4TUQ1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vesicle transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SFT2D1</name>
        <name evidence="10" type="ORF">CEXT_384141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 9">May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011963">
        <property type="protein sequence ID" value="GIY50323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TUQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF6">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY50323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14307" checksum="6ACB9B267DAF7BE0" modified="2024-11-27" version="1" fragment="single">MHQVIDASTLSWSTRIKGFAICFILGFVFSILGAACFALPRGIILFGIFYTLGNITALSSTMFLMGPCNQIQKMFAATRIFATIAVFAFLALTLCAAFWWHKIGLVIVFCIFQFLAMTWYSISYIPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TWQ1</accession>
    <name>A0AAV4TWQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-tocopherol transfer protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TTPAL</name>
        <name evidence="2" type="ORF">CEXT_300151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011920">
        <property type="protein sequence ID" value="GIY49986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TWQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF130">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="93"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="313" mass="35755" checksum="BED1FC88471AFC69" modified="2024-11-27" version="1">MHLHPSWMKGLTPDMVKKAEDELRETPEKKAEALKEIKILIQEEPGFGPLQDDEFLVRFLRAKKYDVDRAFNTLKNYYSFKSRYSGIVTDLTPQDLKFVFEMNKVFVPTKRARNGEGIIIVKAGAFDMEACTLEQHVAAGFIGVEVGLQTEATQVCGGIMVIDMKGMTWRKLMVYFNPTFITTIVRCIQDVMPSRVSGIHVVNEPVYFGSVFKLVKPIITKKLRSRLHFHSSDLKSLQEHLPPETLPKELGGYLGEEEFRSFRSMMLQNNALIERLSAYTYNGVKSSYQQTLEKENKSALHLTTKDLFNVSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TXG2</accession>
    <name>A0AAV4TXG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_220401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011886">
        <property type="protein sequence ID" value="GIY49786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TXG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11233" checksum="BB6D7BCB9590B10D" modified="2024-11-27" version="1">MVSQVGLWADPWFRQDGPLGLNQMQTLQGFGIIQLELKFKSKQQRYYPFRIYNAILVLHDTEIIITDLVGLWADPWFRQDGPQGLNQTQILQGFALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U3B6</accession>
    <name>A0AAV4U3B6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">R1A1-elementORF2_347</name>
        <name evidence="2" type="ORF">CEXT_417141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012216">
        <property type="protein sequence ID" value="GIY52246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U3B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09276">
        <property type="entry name" value="Rnase_HI_RT_non_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="269"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="532" mass="60308" checksum="D4BBEB26536B00BE" modified="2024-11-27" version="1">MEVSDNISNSDHNLLLISWSMDQPPPPKRIHVNNSQTNWLSVKSAIFNIIRAHSSSGFSDVNGLISTIQTEITARLCTTSKNKRSPKRVNGAVWWTQELRAKRSKTRALRRLYQKEKEPTLRTTKLAAFKRCQAEYKKMIINTKTNKFKSFINSVTTSSFFGKNFKILTHKKSRQSSLNCILRDDGSTTSSLQDTYSEILSFHFPCSASVDSLPSSFSSPQDLVPITTMELEAVIEGIEPKKASDVESKPTFDPPWNRFKITWNVFNNDVRGFAIFTDGSKLNNNTGCALVVFIDGHEAECILCKLNPEASVFMAEMKAIEMAVNLIVSRGITDATIILDSRSALLALGNPLNNSPYVSKVKDLIRNYAHYIKFMWTRVHVGTAGNEAADAYAKMSTDKNTIDCHFALAISLLKHLLLKDILQQWQVYWNSSLKGRAVFELCPVVSLKRLHGNFYLNQLITGHGALAKYQKKFFHKDEVCSCGKAVEDRTHLILHCERWQNFRKKHFPKNFLQCSLLQLFAIKTLGQDWKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U4P1</accession>
    <name>A0AAV4U4P1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_208905_1</name>
        <name evidence="2" type="ORF">CEXT_428971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012277">
        <property type="protein sequence ID" value="GIY52697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U4P1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043122">
        <property type="term" value="P:regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049342">
        <property type="entry name" value="TRAF1-6_MATH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF157">
        <property type="entry name" value="RECEPTOR-ASSOCIATED FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21355">
        <property type="entry name" value="TRAF-mep_MATH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="1">
        <location>
            <begin position="15"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY52697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="456" mass="51465" checksum="D4343FB0ACE9F1A5" modified="2024-11-27" version="1">MPQVAGPAIRDQQLVAEFIWRVPHIERKLQLAQAGRLSHLLSERFYSSAQGYLLQMQVKFQNTSLGLYLRLLEGRNDASLKWPFDKRFHLLVLDPREGVGHGAVSVDPMDPRVGQEACSASFWRPLAQNDACGSANALSYDQLYEKKLIRYGAILLKAIIYLEEVLPPRFATLTFQENYMSARFEWLVPDLPSKINQFREGQLAFLDSDKFYLSNNGYRMMLRLYPEKARGFVGLYAVLTRGAYDAELRWPFPHAYSLEASVEGRPPLRRTTRPGHGCPNVAFQRPDRELSEWSCGEGHMVAHETLLGPERQDGPLPLGVRFAITVFLQELVSPVASLRLEGSVLVAKHSWILKDATANLGLLKEQLIGLHWSLQVGPHDDALQWPFMSSISLSLETGTTSLVRLIDRHQCPIGTFDRPTGPGQYCGFPTLITLTTLFSEYIQRDMVHIKASISLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U595</accession>
    <name>A0AAV4U595_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_71261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012305">
        <property type="protein sequence ID" value="GIY52890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U595"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8763" checksum="FC96631F794BCAB4" modified="2024-11-27" version="1">MPDIPLYGFRFRYFPALVLSPQIHEYIFEYGTNFCWCDRSLRSSHYLSSCEDKTHAGIICKKEGIQLGLSVLDDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7Z4</accession>
    <name>A0AAV4U7Z4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RRP12-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RRP12</name>
        <name evidence="5" type="ORF">CEXT_220581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012427">
        <property type="protein sequence ID" value="GIY53891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7Z4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012978">
        <property type="entry name" value="HEAT_RRP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052087">
        <property type="entry name" value="RRP12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287:SF1">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08161">
        <property type="entry name" value="RRP12_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRP12 HEAT" evidence="4">
        <location>
            <begin position="12"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="588"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="443"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY53891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="693" mass="79283" checksum="E33BEC3CE4361AFB" modified="2024-11-27" version="1">MKYIHFFPSFIKAKILQQEGRLVESKLFEVVCLQIWSLLPGFCTEPTDLTMCFKDVAPKLGKLLNDDKLGQFLPLKLTILNSLRLLIKNEEHKGEMSKYAKNYIPILFNLYLTETKNKEEEKIRLAVYETCKLYIQIADRTLITIYFQTGMQKMRSSESKDFILHGTLDVCKAMISCIDGDQIKELYEYTKPLLQNENNTTKKKIYSLIKEICSSESESCKSFIKSHLSDLRLLLSETMNGLTPATRALRLNCLEHLVSQSTIDEKSTVVDIIPEAVLCTKENSVKARAAAYSLLILIGHALHKFTPDNPKGCLKEYMTYLLAGLAGNPHFISATVLAIGRVMYEFKDELDSDIISNLISIMCELVKAKSREIVVSALSFFKILFATVDANVLQPHVKTMISSLTSIASDNQRAFRFKAKELFTRLVRKFGYEMISKMMPPNYQKQLNNIRKIEARKQNKKERQNYGDEEEDDSDLEIDLLADSDDDIIDDNVKVKASKSRSKKLKAQFFQEDAEDNIVDLLDPVTCNRSLTVKTENQMKRKRQNDDFKLSADGRLIIEDEDDGKKSELKSKDENNLLSDVIEPLQKRKRKFDDSDDEADKTNSAPLVHKGIHRTLESKAKRRCPGEEFKAKKAGGDIKKGKLEPYAYVPFNKMALNKRKQMKLKGQFKNFVNAAKRGASVGMKRKKENRKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URG2</accession>
    <name>A0AAV4URG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_447671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013347">
        <property type="protein sequence ID" value="GIY60592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11346" checksum="3C179B9F0A70B2D6" modified="2024-11-27" version="1">MLQQAGIVVPPAICRSENIDGPRGEQIADCGVNETEIFPSIFSWSRLDNFVMDCISDKDAKSVEEEEEKRHWHNQKRKHHKTKQGKKRKKAKTLFPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4V0</accession>
    <name>A0AAV4V4V0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">CEXT_383101</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013943">
        <property type="protein sequence ID" value="GIY64949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4V0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY64949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9972" checksum="8F21E221043690EE" modified="2024-11-27" version="1">MVCSCTFHSDTSDSADVLCVVERNSSPAMYGITMFWFIVLALLSCLSCIYKCFIVAFPSFRFGMVLSRSSAYDPKLMEHYVDNSDLKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V6F2</accession>
    <name>A0AAV4V6F2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">JNK-interacting protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Protein sunday driver</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">syd</name>
        <name evidence="14" type="ORF">CEXT_774171</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK-signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. Syd is required for efficient kinesin-I mediated axonal transport.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms homo- and heterooligomeric complexes. Binds the TPR motif-containing C-terminal of kinesin light chain, Klc. Pre-assembled syd scaffolding complexes are then transported as a cargo of kinesin, to the required subcellular location.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Perinuclear region</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the JIP scaffold family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013964">
        <property type="protein sequence ID" value="GIY65115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V6F2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008432">
        <property type="term" value="F:JUN kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019894">
        <property type="term" value="F:kinesin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030159">
        <property type="term" value="F:signaling receptor complex adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1770:FF:000001">
        <property type="entry name" value="C-Jun-amino-terminal kinase-interacting protein 3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1000:FF:000001">
        <property type="entry name" value="C-Jun-amino-terminal kinase-interacting protein 3 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1000">
        <property type="entry name" value="arf6 gtpase in complex with a specific effector, jip4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039911">
        <property type="entry name" value="JIP3/JIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032486">
        <property type="entry name" value="JIP_LZII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034743">
        <property type="entry name" value="RH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034744">
        <property type="entry name" value="RH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13886:SF4">
        <property type="entry name" value="JNK-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13886">
        <property type="entry name" value="JNK/SAPK-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16471">
        <property type="entry name" value="JIP_LZII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09744">
        <property type="entry name" value="RH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51776">
        <property type="entry name" value="RH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51777">
        <property type="entry name" value="RH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RH1" evidence="12">
        <location>
            <begin position="7"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="RH2" evidence="13">
        <location>
            <begin position="471"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="206"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="445"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00082388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY65115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="527" mass="60449" checksum="D567AF7BDD70158A" modified="2024-11-27" version="1">MESPMQETVYGTNSEDSHVMSEKVQSLAANIYQELERMMEKYDEDVVKELMPLVVNVLESLDSAVMDNQEHEVELELLREDNEQLATQYERERQLRKAAEQKLIEIEYSTDDDRQNLSEKVESLESLVRICSRLEEKDSETRKEYATLHERYTDLFKTHMDYMERTKILFGSEKLEALNNKTRFLHFPHMKSDVTSFISPQESGNKILNSPLDMPSLVSPNQSSDSNASLKKAAYASIATSPRRKSGSKGKEKSVTEKGQLTDRVPLSDRSTGTRDGWVDDLDANLNDATIESPEMDEVEELDGFSFNLENSKLQSERRRPNTLYQELSFQDNDALVEMDEGADISVAGGFAHSGDYASSESDGESEREPKVNDNFFGMGTVENLISENNELLATKNALNVVKDDLIAKVDELTSEQEILREELKQYISVKERLKQKVADLEEELKKARESGENTKSGKSDDEEELPMAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRSDSSLDTKRNKSSIWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VBR9</accession>
    <name>A0AAV4VBR9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Neurogenic locus notch-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">X975_26662</name>
        <name evidence="3" type="ORF">CEXT_249181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014284">
        <property type="protein sequence ID" value="GIY67821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VBR9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963:SF39">
        <property type="entry name" value="DUMPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963">
        <property type="entry name" value="ENDOGLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="353"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY67821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="497" mass="54281" checksum="A8FB88FA97D651BB" modified="2024-11-27" version="1">MTRIASTSDARILAVSSERAESMPSAIPTITKPYAPCEPGYTGDPKKSCILTNQPVGCVDDVECGAGFICEATQCFEGCRSDHQCSPDSACVRRQCDKVCHQPNVCGINAKCMADNHRPICSCNPGYLGDARVECRIVEEPECRADNQCPFRHICVYEKCIIGCHTDENCGADEACINKICQNPCSIFGACGRNANCRPINHKPECTCPANFRGNPNVVCELEVKPECEIDQECNVGKICENSRCVSGCRHDNNCPRHLACVNRQCQDPCLLPNSCGISAECHADNHRPICTCPSNFRGDAYIECRIAQPDVECEHDLECSVDKICENTRCVKGCRSDANCRFEETCINQVCQNPCSIYGACGQNAICKAINHDRVCACAPGYSGNPHTLCSRIPVLPECIVDRNCSLGQICQNQRCVTGCRTNANCPYDETCLHSHCQLVCQLSGACGQNARCTPVDHQPHCSCPADLTEIHRSRASPFPSLVVEEILIVLSARYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFN4</accession>
    <name>A0AAV4VFN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_35011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014426">
        <property type="protein sequence ID" value="GIY68701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="30" mass="3421" checksum="43041E22D21DBAE4" modified="2024-11-27" version="1" fragment="single">DFRSAAGEKIDENFRSLKSWAGHGRFLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VM36</accession>
    <name>A0AAV4VM36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_394641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014699">
        <property type="protein sequence ID" value="GIY70654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VM36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9237" checksum="E089A00CD6E5B43A" modified="2024-11-27" version="1">MEGFFLGKCIRCIKMAIIFDECLSIIRVGSALMSVGNCKGIKGEVSLILLSRTDEDEDSDWWDPLECLLLTDLLITMRVKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VQ61</accession>
    <name>A0AAV4VQ61_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_559951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014823">
        <property type="protein sequence ID" value="GIY71535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VQ61"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY71535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10175" checksum="1BFB2F902400FF6C" modified="2024-11-27" version="1">MPSPLLEEGRFELCMSDLQIPRRTRQAHIGPGALSRKIVHSFCGTDATRGTKLKANSCDDLSLIGNHYDLGRWRQTAAPSLRLSSAHSRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWD7</accession>
    <name>A0AAV4VWD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_34801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015139">
        <property type="protein sequence ID" value="GIY73909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20374" checksum="BE75BC941804AE71" modified="2024-11-27" version="1">MPGLNLAPVEQLPTRVFNWDKPLVKIAYVGRFLKFIQRSMKETWIRKSCKTTDSAGPRAINCLEGGAEETGHQPRRRSAVVWAESLLCTFSCKDHIPRDLVLLHFEEHNIFVKSDTAITGFMRHKEPVVADIQRSQFAKLQPMAENISTHMGRIVRQIQSQAVLLLDSIIDFESGNSTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZX7</accession>
    <name>A0AAV4VZX7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_474631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015334">
        <property type="protein sequence ID" value="GIY75395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12295" checksum="9140FF0701ACAD01" modified="2024-11-27" version="1">MRVEVTDAVKFVDRIRPQVHATAATCLLWTFLGAELTRMVARGAHTLECRYLAALGKKSGSSWGGGLQSESDDIDSPEEKRADDEVREELSLVWHQVLRVRDRRRQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4P0</accession>
    <name>A0AAV4W4P0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AP3S2</name>
        <name evidence="8" type="ORF">CEXT_263642</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015612">
        <property type="protein sequence ID" value="GIY77363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4P0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="13"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY77363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11188" checksum="65A39E49BF904CD6" modified="2024-11-27" version="1">MESRDFQNSMKFYPEDMQQQIIRETFQLVSKRDDNVCNFLEGGSLIGGSDFKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFEMSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEV9</accession>
    <name>A0AAV4WEV9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_123841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016003">
        <property type="protein sequence ID" value="GIY80359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEV9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY80359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10569" checksum="172A1F102A2A30AA" modified="2024-11-27" version="1">MYKKGYNELPQQKQELKRLPSRPQAKIPKHISGKNFKLHPMVFVEVEKTHLKGFLSKSEESLLVPFLHSPFLWSFREKDRKTDHKIKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHQ1</accession>
    <name>A0AAV4WHQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_203531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016240">
        <property type="protein sequence ID" value="GIY82360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY82360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12731" checksum="4B85A80A3B3C73B6" modified="2024-11-27" version="1">MNTPEETTEVYSQVSSLFLKRGFELRKWRSNSFQVLRKLNVIKEENRFEIHGGTKCKVLEVYPIQKQKSNYTSYLHASEQDYATLICCRQKSASAVAVNLLASKTKVAPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WQB8</accession>
    <name>A0AAV4WQB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_376891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016525">
        <property type="protein sequence ID" value="GIY84523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WQB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY84523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9564" checksum="534A344EB38EA044" modified="2024-11-27" version="1">MGGAICSKRSHCQRVCHNSPRYGLLRPVIMDNGQFSSTMSYQAANPTNPIPVATYHVSVPVYLINRTTTNSATEKKEIRSPRKTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X1Z5</accession>
    <name>A0AAV4X1Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_707671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017158">
        <property type="protein sequence ID" value="GIY89127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X1Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="181" mass="20359" checksum="A10ED17EB4E496E0" modified="2024-11-27" version="1">MRSIEQLANSQHFGTLLHLIVTLAQFECLCQPIRNINGIFALRKLYDEINVQIRSLESLGVNSVSYGLFITCTTNSGHQNSLCNQTKTAIILQKKKNSVNLLNVDPFSGKESPGFPVFFQTIKCKLVSRNEIVNVRFLDIGSAELFTIRGLARRLGLQVKGQEELKNYCLLEKKILSLLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAB7</accession>
    <name>A0AAV4XAB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transient-receptor-potential-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">trp-1</name>
        <name evidence="10" type="ORF">CEXT_256921</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000022">
        <property type="protein sequence ID" value="GIY91539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070679">
        <property type="term" value="F:inositol 1,4,5 trisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015279">
        <property type="term" value="F:store-operated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051480">
        <property type="term" value="P:regulation of cytosolic calcium ion concentration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007338">
        <property type="term" value="P:single fertilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002153">
        <property type="entry name" value="TRPC_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10117">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10117:SF80">
        <property type="entry name" value="TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="9">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY91539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12450" checksum="8BDD78A2356EE2F7" modified="2024-11-27" version="1">MERHHWPDNDPTLIAEGVFAVANVFSFARIIYLFQTNPHLGPLQISLGCMIIDIAKFLFIFFLILTSFACGLNQLYWYADYMEEGCQMKGDNTTSSSTSCYQNSEPFMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBD5</accession>
    <name>A0AAV4XBD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dscam2</name>
        <name evidence="3" type="ORF">CEXT_155531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000020">
        <property type="protein sequence ID" value="GIY91505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000104">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="63"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="157"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="255"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY91505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="295" mass="32583" checksum="88CC13F3AB34BE88" modified="2024-11-27" version="1">MLLQKEGRPLPVNQRQRVYPNGTLQIMDVQPGEDNGQYSCEVTSGEGMQPASRTFRIIIRAGPKLASFTFRDNLHEGMRTAVTCIVLGGDGPLSLRWLKDDEPLTEQELNVNILQEEDGSISTLTFKNLTYKHNGNYTCIVTNDVASGSYSATLTVKRWMLEPSDISTVAGRPARIDCQADGVPQPHVRWKMAINQPPEQFKTIVSSSHIHILVNGSLNFRSVETTDAGYYLCEANNGVGSGLSAVVRLTVHSAPHFLTKFMVVSTRRGDKVSIDCTPEGDRPVTFTWRKNGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD99</accession>
    <name>A0AAV4XD99_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_352441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000250">
        <property type="protein sequence ID" value="GIY93231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD99"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12382" checksum="E4B0C40F267FC288" modified="2024-11-27" version="1">METRRELIQDNNKSSTRTTVKGEKKQAFLHSIVLNSSTYEFLTRGSCTRGRTICLPSIAATWRIGSAPASKASERQQQERKKKRKEEKTWRLESNVVITTRRKRGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFY3</accession>
    <name>A0AAV4XFY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_372331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000278">
        <property type="protein sequence ID" value="GIY93542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="11072" checksum="DF487BBE46BB0298" modified="2024-11-27" version="1">MIMEEVQQKKEASITKYKKLPPFHLDSRIPFLLRDNSNFRNFFLIKCYVTHLFFSHFNLNLQNCRTFKAVKITFKKCLQLRFTQPALIELSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH19</accession>
    <name>A0AAV4XH19_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_99311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000370">
        <property type="protein sequence ID" value="GIY94256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH19"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9777" checksum="9827C16F682351AA" modified="2024-11-27" version="1">MEAKGGGGGSGRWPLPNVRCFGGPALRHRVQLALAGNALGQHVHCVYVGYCDDPRRLVCPFTFRTGRATYGSSLSKPEDADPLKYFEEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XJE7</accession>
    <name>A0AAV4XJE7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">CEXT_608941</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Apical cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000324">
        <property type="protein sequence ID" value="GIY93903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XJE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048592">
        <property type="term" value="P:eye morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051093">
        <property type="term" value="P:negative regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051241">
        <property type="term" value="P:negative regulation of multicellular organismal process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003002">
        <property type="term" value="P:regionalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060255">
        <property type="term" value="P:regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008593">
        <property type="term" value="P:regulation of Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000565">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051355">
        <property type="entry name" value="Notch/Slit_guidance"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45836:SF23">
        <property type="entry name" value="NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45836">
        <property type="entry name" value="SLIT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00010">
        <property type="entry name" value="EGFBLOOD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="9" id="KW-0221">Differentiation</keyword>
    <keyword evidence="12 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 14" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="EGF-like" evidence="15">
        <location>
            <begin position="53"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIY93903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="11100" checksum="998E569387A1063C" modified="2024-11-27" version="1">MFANVLPGYTGSNCQFHINECDSQPCQSGGTCVDHVGVTLATVRLDIQECTTFVDWCSTNPCMNGATCMQLNNTYGCTCQPGWTGKLCDVSMVSCSDAAAQKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK46</accession>
    <name>A0AAV4XK46_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_563901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017767">
        <property type="protein sequence ID" value="GIY94305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK46"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8171" checksum="C3BA675973C1DA01" modified="2024-11-27" version="1">MPDNKLPKVPKSSATKFESRKRSRLSKSFAAMKAKGSRAASLLKFPSFGVGVDGVSSPDTQEDATFYLQCLSPSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XMU2</accession>
    <name>A0AAV4XMU2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_482001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017905">
        <property type="protein sequence ID" value="GIY95384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XMU2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13271" checksum="F022BAE5333ACA07" modified="2024-11-27" version="1">MCETKMVTQAQSPDSLLLTYLSKVQVGGRLLLANQMVNQIVCYFFFNSLMMRKQAENLALTSERASEGRRSKSMQKWEKGESCNRDAIRADVTDNSSVSGFTDLPGDSGVNKLSQACCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUK9</accession>
    <name>A0AAV4XUK9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vitellogenin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_129181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018352">
        <property type="protein sequence ID" value="GIY98875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15795" checksum="FEFC228CDE0DDE37" modified="2024-11-27" version="1">MIISGPHSMPVLILAPLFTSYLMLLGSSKYNLIVWATRDSPIIVESTEKMQTVNYVSYPTEGEGWIPGCETRTLNKPQMWTSMAVWKEGSEKVVIHIAPRILNQTKEFITGLTESIEAQEAYRSVKLAPRVQSQWLEIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUM0</accession>
    <name>A0AAV4XUM0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_669731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018292">
        <property type="protein sequence ID" value="GIY98432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUM0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12073" checksum="03D394954FAF8858" modified="2024-11-27" version="1">MIIYGYAKACLIQRQTVGMKNFQPLQLFGVPAPIHTSRPILRLSKQAFVNSTTAFHIEDATSLFKSCFNSNLSWFIDRVNLAIGWISRAWWNLQATHRNGFKKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWA9</accession>
    <name>A0AAV4XWA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G_PROTEIN_RECEP_F3_4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AVEN_132190_1</name>
        <name evidence="8" type="ORF">CEXT_286761</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018318">
        <property type="protein sequence ID" value="GIY98603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13953">
        <property type="entry name" value="7tm_classC_mGluR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="7">
        <location>
            <begin position="82"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY98603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="395" mass="43801" checksum="38E9E3BBB4B8772A" modified="2024-11-27" version="1">MANRTNSSNVFSPPPQWTPNVTHIIPGTSFLNCSLITDNVHRRKDSWVIPLVVLCTVNITAILLFEIYVLYKSCGSRRHLFLGQILLLGLFISSLLGFAFVPTPNWFTCALIRAGVGIAYVLIFATLLVKCVFLLSLHVGVYLSAAYQGLLLFFAVTVQLVIAVQWLIYRPESLVIVNQFSCATSCALTIADTVASLAYNMLLMVGVALLAIRARTVPENHRESLYIGVAIGLTIPLWVAWIVIASVSSIEHHDPCLAFGVVITASIVFLVMFLPKCRQLASMGRGGPYTDDGFSSVNQSIYTPSFLHLKPPIMPFVKQGTLVKPLTSTFPAHPVERNYYVPPLQHASRLWRYSHHPATLQLPPPLHPSSEDIYLSSDRYLFGPPGMKLYRSPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWE9</accession>
    <name>A0AAV4XWE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_224971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000899">
        <property type="protein sequence ID" value="GIY98209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043674681" evidence="1">
        <location>
            <begin position="18"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="19662" checksum="407C4F6509B9ACC7" modified="2024-11-27" version="1">MLILALALGHFAGAVPCLRPRPECPAAINRDFSGAGFNCETLRNFPGHSFVSGRKTPALIMERGFADIFGAVPCLRRRRECPTAINRDFSGAGFNCELSRNFPGHSFVSGRETPALIRERGFADIFDSGADRNPEKRANKQHLKTFIPDSTAGNSAGPTENRYATVPYHDHSNAFVAIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXH6</accession>
    <name>A0AAV4XXH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_334151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018421">
        <property type="protein sequence ID" value="GIY99459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10752" checksum="D926065790F8A28C" modified="2024-11-27" version="1">MEIVKRVNSKQKFGKLPFSFVKYVVCREIVVNQGTVVSLCPAFAVVNLIDLHALYRLDRESLSLRQSLEIIESLIVQAVFLDSALKVRRKFVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXT6</accession>
    <name>A0AAV4XXT6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">R1A1-elementORF2_476</name>
        <name evidence="1" type="ORF">CEXT_180371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001006">
        <property type="protein sequence ID" value="GIY99113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29868" checksum="24E90618D64AD312" modified="2024-11-27" version="1">MGGTSLENRRSKGWWHKTGAFRLFTSVVPSIHTETTPFLTLLFTSPPWNRFKISWQHFDHDISGLSIYTDGSKFNNNTGCALVVFRDGIEVHHLLCKLNPEATVFLAELKAIEMAVNLVVSQSMVNAEIISDSRAHVDTAGNEAADAYAKLSVGNDSIDCKLELPKAILKIFLQQDTLQQWQVGWNSSLKGRAVFDLCPKVHLKRLHGNFYINQLITGHGALAQYQGKFFGKDDFCSCGKAVEDRLHLVFHCKRWQGLRDKWFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYT0</accession>
    <name>A0AAV4XYT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_649351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001143">
        <property type="protein sequence ID" value="GIZ00282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14158" checksum="B2AC40567299A16D" modified="2024-11-27" version="1">MPGHCLACSLHKRGQQFFSQHSDSLWVPVAQRCSKYLLMLRTTLGLKRSDSAVRFGLNRPWASSRPEEFGPQIIIGFKSVSWTNCDGFNFGHFPTTMKLDALHSRVNAHHSLKENDLAQQEVDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y259</accession>
    <name>A0AAV4Y259_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_182051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001318">
        <property type="protein sequence ID" value="GIZ01561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y259"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF23">
        <property type="entry name" value="TRANSCRIPTION FACTOR SP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIZ01561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="291" mass="33654" checksum="C0978D2178B98576" modified="2024-11-27" version="1">MEITKCEFCEAYITNLEVHNCVRLGNQYRQTFATLPQCSSDNAAGVNELEEMDYEALWPSLYQSNSSTQQSILPDVYQRTDWEETAAAVMPSQQGVANQNPYNPETSDFLFPHIQEKELVSTHLKQPYEVSKVFINQYPQNYEPSNPKRPDNPPMPVATLCVLPGFQETFGRRNPISNTILPSASSVNCEQNTEEKILDLNTGVCEQKADEPQKTKNTLHKCSRCPMKFKRKDYLESHERVHNVEKPYVCNFCDKVFSNADHFSWRRPFRTQPINLNNSILYEHRGLVKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y321</accession>
    <name>A0AAV4Y321_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_742401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001209">
        <property type="protein sequence ID" value="GIZ00806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y321"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="20826" checksum="9E76BCFEAE912B15" modified="2024-11-27" version="1">MTRKKYLIFEYPKEPLNFTKALRTKHYLLKICKPLTIRRDPSRSHFWDADKHGGGGEGLCHKCCPSPHSKDAENSDDLGPKRSIARRRSIPPFPSANPSLPHNLQPLRTCSRNNHIIKFNVNPTTVVDPFGTQMFLGRGESNVLIHPRDRGRPGGVGREEACVTFPSYLFFFWGGVGDSHLPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y437</accession>
    <name>A0AAV4Y437_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gamma-aminobutyric acid receptor subunit rho-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Gabrr3</name>
        <name evidence="6" type="ORF">CEXT_279291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ligand-gated ion channel (TC 1.A.9) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001266">
        <property type="protein sequence ID" value="GIZ01220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y437"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="293"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIZ01220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="325" mass="37161" checksum="4FFF704357FD35A2" modified="2024-11-27" version="1">MQKVKVVHQSFKATEAMQPFKQRMPEFPKRNPSTTKMDTTNPSGKSQNKRSTSKKIRINRQNASPEGAKENIFPPDYNKQSSPGITGTPIYLFIDLSVLDIDSIDEAKMHFSMQVYVREIWKDSRLNLTCLKPVAFINTDIPNEIVQELWTPNLVFENAKSGELFNVLVPNTFTAVLPNEALFRASRYNLIIGCYMNFMYYPIDVQECYLQISILANTEKRVILRWAHEDEQLKMFFKGVSFGNKIQSLKYELLPPRPYRTKERFNHAQVSSMSTFRAPWWCSCHGHRFGLMSGPSQPGSPSGDVLSDPCDSDDSGSEQPSCHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y5I8</accession>
    <name>A0AAV4Y5I8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_568911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001310">
        <property type="protein sequence ID" value="GIZ01480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y5I8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="8017" checksum="7F786AAFC27C2675" modified="2024-11-27" version="1">MILTQHQLRRVHPPSPPPRAQYRSAQCHSDTLNARQTRGPPGLLFHANIPEQTNEEQKEKWRYVFQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y677</accession>
    <name>A0AAV4Y677_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_356741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001471">
        <property type="protein sequence ID" value="GIZ02528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y677"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="24955" checksum="85F48EE6EFD34192" modified="2024-11-27" version="1">MYATFLEVSEAERLIKGKIISEGTSKDHLRKNDEVKKKKKREGQDGRGEKKDGLELLQLRSRTSESSIKIKSAAPRCPALVTAVKEPLSPCSCSNRINPDAQEDTSRVRKRNLSQKICKKMSIVGHRINNTTESIMIHKKTTAEKCFRLPDEQGRLRCKCNLASFTGPSGWAHDLTLPKLNSSQNNDRIVHRHNNSIYTRRKTEVRGQRRKGKRTEEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6S1</accession>
    <name>A0AAV4Y6S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Dscam2</name>
        <name evidence="2" type="ORF">CEXT_636791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001401">
        <property type="protein sequence ID" value="GIZ02150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="37"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16463" checksum="6ECC25CF9CCB850F" modified="2024-11-27" version="1">MNRLGVKLLDFALLFSEKKFRSNLRLCDRNQNDQRGPIFSTEPPSRVEFSNSSGTEVRCVADGVPNPNLSWRTREGGSAPDVPGLRYTKSDGTLVFLPFMKNDYRQDVHDTVYQCLASNSFGSVISREVHIKGGDVSGRSSVGRFMNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAQ2</accession>
    <name>A0AAV4YAQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_500081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018966">
        <property type="protein sequence ID" value="GIZ03539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10299" checksum="9A9D13BCC29A37F4" modified="2024-11-27" version="1">MHFGRRNLKKNDFRLKISLETMNSQSCAWPARNNSGGGETLLVLCLRIVRKFNMFWKREAQKRKCIVVVVVVCGVHFSYCCKKCRKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YG57</accession>
    <name>A0AAV4YG57_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_651891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019254">
        <property type="protein sequence ID" value="GIZ05264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YG57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ05264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17971" checksum="0C6D6EB57DFF4365" modified="2024-11-27" version="1" fragment="single">LALYCWSETRPQASPLLRFRQSAFLGRYCLCIQLLPWKLELIAGDLGEVLCRTQEGLIRLTFYLPGDITLSLSRHGSIDRFGESEETFSEYKWTVARVITGLSPDENLCRTTSGRCQGTFTSLEIKMLMDNIASREVELKFKMIWFRGSCSMHEACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4I2</accession>
    <name>A0AAV4M4I2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inverted formin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">inf2</name>
        <name evidence="3" type="ORF">CEXT_218421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019375">
        <property type="protein sequence ID" value="GIX67120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4I2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.150">
        <property type="entry name" value="Formin, FH3 diaphanous domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46345:SF8">
        <property type="entry name" value="FORMIN 3, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46345">
        <property type="entry name" value="INVERTED FORMIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="2">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX67120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="362" mass="40059" checksum="30055F62C50A3E2E" modified="2024-11-27" version="1">MERGRVLNCSYLFVVLGLDSTNVSVKKQAFELLSALCVYNAEGYQRALDTLEHYKTNKKERYRFKVVVDELRSSDLDYLSTVVAFVNCTIISVKSLKDRIRIRNEFIGLKILDALSRLRATFNEGTESELFVQLDIFDEHRLSDECQSTGPNGVDLNSHQDVFYAILRQVAETPQEIPFLNILQHLLRVDTSLPISDIIWDTAEKLVHRATLCETKEDSEKLLRAPSYHHSLNKLLRGLQESGGRCQCSCHNNGEISNSAATDGRTRKRTPLQLSFGDGSKTPGILSPTNSSMAFSPELLATLSRAISPPPRVSNASMLPAVGGPPPPPPPPPPLASPPPPPPPPPGGEEPHLHLPHHPRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4S1</accession>
    <name>A0AAV4M4S1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein MMS22-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_20391</name>
        <name evidence="1" type="ORF">CEXT_740081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019394">
        <property type="protein sequence ID" value="GIX67374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4S1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17817" checksum="A75FEC61B7EE33C9" modified="2024-11-27" version="1">MFPKDKQAQSTVSHAIKEYLPNFIRGIFKLDYRKEKVVEKALKEVLLNYVCIHPSSNNPISKLCIDSVHNREEGLKWDELQFLLDVMKNSVLNSNTNPMNGFELIFEIFKATPLSRTAVIANILLRSTFEIYMKQGSTFIPVFKKFNVQSLLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6B9</accession>
    <name>A0AAV4M6B9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MRH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ELAPOR2</name>
        <name evidence="9" type="ORF">CEXT_772991</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELAPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001889">
        <property type="protein sequence ID" value="GIX67596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6B9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039181">
        <property type="entry name" value="Elapor1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056607">
        <property type="entry name" value="Elapor1/2_MRH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22727:SF15">
        <property type="entry name" value="MRH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22727">
        <property type="entry name" value="PROTEIN CBG13728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23087">
        <property type="entry name" value="MRH_ELAPOR1_9th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="8">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX67596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="31115" checksum="FD1498E50531B7F2" modified="2024-11-27" version="1">MVNSFVCRATIVPSQNGDGRESLVTQSVSIGDTLVGITTKHQLGNMEVVEEFVHSSEGQSDIHFFYTSPEKTQACSEGRSTTITLRCDSNMEGNGTIYPPASCSDGTCDGCNFHFLWKTRLACRVCTESDYQIVKGECLQGKQTLHYISPQGCILPDGSSEAAFRRTVPCTIIPKQFQLLIGAGVAIGILLLVMVVYFWKKNRKLEFKYMKLVQSSSSKDCELPAAESCAIDEDEEEHFDSVAFSDKKKGILGKFRTIRVGNNKVYWESETQALDGWTPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M6L0</accession>
    <name>A0AAV4M6L0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_195041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001917">
        <property type="protein sequence ID" value="GIX68019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M6L0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8037" checksum="31D70504F12840C5" modified="2024-11-27" version="1">MGTLFHSHKIPRNFSRKETPYPPPTNSLKTGPSNPPRSDGGGGAVLREQWEREGGRNLINRNEGVAGPSGEEPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M907</accession>
    <name>A0AAV4M907_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019508">
        <property type="protein sequence ID" value="GIX68627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M907"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="9030" checksum="9425410B28413B15" modified="2024-11-27" version="1">MFIADQTEWHLRLYPHGYNEADGYISCDLKMVSKQKVMVAFTISIVCADGLEHFSVEKVDQQFPNDTFAGPMHFCRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAQ8</accession>
    <name>A0AAV4MAQ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rut_1</name>
        <name evidence="2" type="ORF">CEXT_462031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019586">
        <property type="protein sequence ID" value="GIX69466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAQ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13226" checksum="5EA1CA93205B9CCC" modified="2024-11-27" version="1">MYTHPRAHSVNKSPAVLTPPEEMFNFPSMNAANNTESKDPALANDTSFAINSSSDSILGHEQNNSVDSSSLNRSSTSSCESYVRTDFSRTDVDTPSPALYDYPCQTNVQWVYPADMKNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MF89</accession>
    <name>A0AAV4MF89_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_36181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019689">
        <property type="protein sequence ID" value="GIX70654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MF89"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="14981" checksum="5862BD3B2EADD81C" modified="2024-11-27" version="1">MDGKMRKEQDNDSSKRKVKHTSDSEAGSEIEKVGELFNLGEGPFLKFWRESGGGGGWKSQRKWKFWTPAQITPLGFEGKVNGARVGSHPTFAANLLPSLVKGCRRMLESPMVGPEHQEKQFFPLELQQQVNYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MH47</accession>
    <name>A0AAV4MH47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingomyelin phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_209481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002227">
        <property type="protein sequence ID" value="GIX71522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MH47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX71522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="203" mass="22576" checksum="B52ECEADFEF0633B" modified="2024-11-27" version="1">MGNECARITSPLHNWTVPLTAFPKPLYRKYWSLKDLQCCACCTSQTLTWTPTAWKAPTPTARSSCAAAQRTATPHPSQAAGKWGTTGTHDTPPPHPGEHAAPHHLQTQNRLRDLDGRHSPSRRLEYHEGRAGEAPPPLVSKILAKHLPGTPVYPALGNHESARINSFPQPEVTGKFSIQWLHEEVTKAWGRWLPVDAQRTLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHB8</accession>
    <name>A0AAV4MHB8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">CEXT_419271</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019803">
        <property type="protein sequence ID" value="GIX71904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000557">
        <property type="entry name" value="zinc finger and SCAN domain-containing protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050589">
        <property type="entry name" value="Ikaros_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24404">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX71904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10469" checksum="0241CA40878494CD" modified="2024-11-27" version="1">MRVHTGEKPYTCEICQKSFAHSSGLLQHAGVHSAEKTHRCDYCDFKTAHESSLKDHLLRWHSEHKEECPLCCNDFYSKEPLHFHKCKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKD6</accession>
    <name>A0AAV4MKD6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ghrA</name>
        <name evidence="4" type="ORF">CEXT_753891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002352">
        <property type="protein sequence ID" value="GIX72838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05300">
        <property type="entry name" value="2-Hacid_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000363">
        <property type="entry name" value="D-isomer specific 2-hydroxyacid dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="88"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX72838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="299" mass="33964" checksum="55BC95C891A14BC3" modified="2024-11-27" version="1" fragment="single">QVKRWDKSIKLSEEGKEVIKNAEALIIDCTYLSEMLHSLPNAKWIQTTWAGLELLMENIDMSKPLPNYTLTRFVDPYFGELMSNYVISQIINIERGMYVYRDAQKTATWSRPFFPDFRVLSDLTVGILGAGSIGSAVGRLLKKAGCRVLAFIRSPRDVTPSDDYDEATTNLNDVLESCDYLCNVLPSTPETQGLLDKDVLKHCLKKPVFINIGRGDIIKESNIIKALKEGWISKAVLDVFEMEPLPPDSPLWNFPEVYVTPHIGAIPRIEGIAKFIAENYVRYIRKEPMVNIVDWKKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKJ9</accession>
    <name>A0AAV4MKJ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein 120 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CG32795</name>
        <name evidence="7" type="ORF">CEXT_568071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM120 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002348">
        <property type="protein sequence ID" value="GIX72767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKJ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012926">
        <property type="entry name" value="TMEM120A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21433:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 120 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21433">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07851">
        <property type="entry name" value="TMEM120A-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX72767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="33238" checksum="D0587919A8E0FEC2" modified="2024-11-27" version="1">MADKTSNLSTVVEEWNELKKSFQDVEVLQKTCSKAVVDFKKSEVDFKKALVEQLKGVTRISESLKCFRPSTEKEKENHNELKKSVNIRKEELRTMSSTLPKDSSLYLKIVLGSVNVSLLNQEEKFKYKEEYERFKLIVTCIVFTLSFLNVLTSYRTLDAILHFLLVWYYCTLTIRESILVVNGSRIKGWWRLHHFIATLLTGVLILWHDGKSYQLFRKQFMYYSCYSSFLQFLQYKYQQGCLYRLRALGERHNMDITIDGFHSWMWRGLKFLLIFLSIGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MKP9</accession>
    <name>A0AAV4MKP9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cuticle protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_42192_1</name>
        <name evidence="3" type="ORF">CEXT_167801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002351">
        <property type="protein sequence ID" value="GIX72827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MKP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF235">
        <property type="entry name" value="CUTICULAR PROTEIN 73D, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043383026" description="Cuticle protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX72827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="14216" checksum="0C560A240016FD80" modified="2024-11-27" version="1">MSTFSVALLVLTISAMALAGPAVPASPILTIQEQPRPYEFGYDFADGLGMSQHRREVADGTGVVKGAYGYQDPLGVYRNVEYTAGVDGYKAVIRSNEPGTSNHVVGDAVYIVELPPPAVVAQGLRAAVPIPRVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVD2</accession>
    <name>A0AAV4MVD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_182561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020249">
        <property type="protein sequence ID" value="GIX76411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8343" checksum="9D28EF40FD8B87F2" modified="2024-11-27" version="1">MKMIAIVTIDIGSIYTHSRPENSRSPTPLRFHHCPDRPLSNYVLNMGAVKLTIGYPFSPLTEPTRDSSPKSHYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0K3</accession>
    <name>A0AAV4N0K3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_33871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020400">
        <property type="protein sequence ID" value="GIX78302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0K3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15990" checksum="CAC18BAAF705072C" modified="2024-11-27" version="1">MFHHHIFQPLEPANTFKISKNQQNKSNELSPKNIHPRRMGASPLIDPSLSPLKIFPFSPPGVQLTPPPSLKTDGFLPPSYLLQLCHMLDLLKLLSMPFFFHCLLIGYYPFFSLIFYPSRGFFIIRGMVLLQGIYTVTVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N478</accession>
    <name>A0AAV4N478_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_443821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020505">
        <property type="protein sequence ID" value="GIX79524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N478"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11776" checksum="8B3EA0515DA9597F" modified="2024-11-27" version="1">MPISSLPLPCRARKIQSPCGLLRCQARRPLSGLFAIPRGNLRHAEWQQQCIFKKEGKDLHGFREQNSFSKPFKNDFYFLMPFFFKKENKNCVLRFLILPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDE5</accession>
    <name>A0AAV4NDE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_413631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003244">
        <property type="protein sequence ID" value="GIX82508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10198" checksum="F5798F59D6CB8155" modified="2024-11-27" version="1">MYKKDFLGLVFNQSLDSVTVLSCGFLDHFTYPDSLRFLRRIIYEIPVGFSLDQVAFCRRSVLTSVVTALCHGKYSFVRCYVDIRCISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NHG6</accession>
    <name>A0AAV4NHG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_748691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003300">
        <property type="protein sequence ID" value="GIX83171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NHG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX83171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9545" checksum="4185F4A2D694974F" modified="2024-11-27" version="1">MLNPTLPLVVDIAKWEEIYFSIECVKLNGKAKIKGRAVIKNVYDHQTGPCVPLQSCKILLENKTALLPVRCVTLVLKEGISFNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NI43</accession>
    <name>A0AAV4NI43_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_60001_1</name>
        <name evidence="2" type="ORF">CEXT_376221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003389">
        <property type="protein sequence ID" value="GIX83985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NI43"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01099">
        <property type="entry name" value="PAN_AP_HGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052774">
        <property type="entry name" value="Celegans_DevNeuronal_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327">
        <property type="entry name" value="FI18240P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327:SF1">
        <property type="entry name" value="RE15579P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="5"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10628" checksum="8FE222F139D90D85" modified="2024-11-27" version="1">MNPATGSGRSTESRGAALRVRRQALSNIESRDMCLEKCSVEDSFVCRSARYDRFNKTCVLSRHDRRTAPEAFRRSLRQVEYLENQCVAGGKHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NJG2</accession>
    <name>A0AAV4NJG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Probable RNA-directed DNA polymerase from transposon BS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RTase</name>
        <name evidence="2" type="ORF">CEXT_226891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020926">
        <property type="protein sequence ID" value="GIX84066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NJG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="269"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="458" mass="52903" checksum="80FA3E0799C17B14" modified="2024-11-27" version="1">MQKLTLEEVQRPLRPMAELRNRGYALAGYNRVAFMPLTLPGVKTPDVHRPPHPGAPSPYFKVKLDKILELASKHQVSIIALQETKLNTRHRLRVKGYNIVRQDRSSNGGGGLVFLIRDVYFQGIYRINSPRKSLEKGAVPRGKHKKTRPAFTNDSQDLQKLLAKREHLLQSHNLNDNTDARIELNKINTEIKREKENKKTGRATRKLIRSCRVPENNELFNEPITSSELLYAIQQLDFKKSPGLDGIHGQFIVNLGSCATKRLLHIFNLSWKLGRLPRQWKTAIVVSIRKPNKDASCMGSYRPIALTCMTCKLMERIILRRITFHLMNRNMLPQEQYGFRKGHSTIDQILYFVQRVRDAHNMKPSRHTMAVFLDLTKAFDKVWKNKLLGKCFSEFNIKGRVLPWLSDFMKNRSFRVRYQNSLSEIFKTYQGIPQGSVLSPTLFSLYLTGIERDVSLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NY36</accession>
    <name>A0AAV4NY36_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Galectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LGALS4</name>
        <name evidence="6" type="ORF">CEXT_420911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021445">
        <property type="protein sequence ID" value="GIX89668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NY36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016936">
        <property type="term" value="F:galactoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00070">
        <property type="entry name" value="GLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000124">
        <property type="entry name" value="Galectin-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044156">
        <property type="entry name" value="Galectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001079">
        <property type="entry name" value="Galectin_CRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11346:SF176">
        <property type="entry name" value="32 KDA BETA-GALACTOSIDE-BINDING LECTIN LEC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11346">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00337">
        <property type="entry name" value="Gal-bind_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00908">
        <property type="entry name" value="Gal-bind_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00276">
        <property type="entry name" value="GLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51304">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0430">Lectin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Galectin" evidence="5">
        <location>
            <begin position="12"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU102079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX89668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="449" mass="46016" checksum="A1E60F16C3DFF558" modified="2024-11-27" version="1">MDSNIYNPSIPFIGPLPRSLQTGNIIKISGVVNSSATCFSINLQNGSNSYQRSDISLHLSPVFSSPPRIVRNSLENQQWGPEESHGPQFPLIIGQGFEILILAESDHFKIAVNGAHFTEFSYRLPLQSISHIAIDGDVTINSIKFEGLATSPMQGSGEGISKPLGFMIDPSNQGNLAPPSSSGRPPSPYDTSSMPYPTSFGPSPTSYNPPSGGNYNQNSPSSPYGPPGGYNYGIPPSGGNPYGPPPSGNPYGPPGGNPYGPPGGNPYGPPGGNPYPSPQGYPGQPGPYPSQGYPTSNPYPGQAGPYPGTSVVYPGQEKKSESGLNLGPLAAAGAAALAGVAGSTIMGKKHKKKKHGHGLDIPGMGHGLGPAALMGGVSSFLGGDKHGHGHKSGTGLAAPLAGGAAALAGAYMLSKSPVGKMMKPKKMKKLYKHKGGWGSSSSSSSSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P3N8</accession>
    <name>A0AAV4P3N8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_536901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021564">
        <property type="protein sequence ID" value="GIX91163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P3N8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="125" mass="14235" checksum="32EF3CC2492744A4" modified="2024-11-27" version="1">MHTSNDGRQTIIGKPAGAKLQNRSSQTERIKKQQQNSKIPNSYSPEPLPDSNIFEIQEVLEERKYFVRRFALQASPEQGWRRTNSVSPRSFGGKSRKVSPFGTESPVLRRERPSAAANRECCLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P756</accession>
    <name>A0AAV4P756_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Pde11</name>
        <name evidence="4" type="ORF">CEXT_713701</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004213">
        <property type="protein sequence ID" value="GIX93197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P756"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX93197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="15955" checksum="8DEC8F7E1D551CEE" modified="2024-11-27" version="1">MYEKSMKAIKTKVTHEVLSYHATAFEEVQALLRVSKLCNVLGELETLSLLIACLCHDLDHGGANNSFRKIINFFPFFTNRSNSPLAQLYSTSTMEHHHFDQCIRLLNSEGNQILSRLSSEEYLNVVHVLEDAILATDLTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PKV6</accession>
    <name>A0AAV4PKV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_380871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004640">
        <property type="protein sequence ID" value="GIX96386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PKV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17981" checksum="674EF671F6D57CC0" modified="2024-11-27" version="1">MVNWLWYEFLTIGLASRRFREAEASINTSSSVVLFLRCRALHLRTDTPSYFRFVVSCYRKDSILHDRQDVDEDEKEGVVTLPRLIGQVEEAGQPGDLTVGTLQCVVEGSGRVQKERSNVTWDDPDYAPDSFGPGFRLLHAGFQLVKHCHVSEMEEGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PS73</accession>
    <name>A0AAV4PS73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_296771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004947">
        <property type="protein sequence ID" value="GIX98681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PS73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8936" checksum="3D276ECBC327B78D" modified="2024-11-27" version="1">MSPLRGTVICDCPGNDAKRMIQPPFQFVSPLSLSSGRVDRNINEAGLQQVNCHREKCQSSSPTLRMTFSEKDFSSPEDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW82</accession>
    <name>A0AAV4PW82_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_627361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005355">
        <property type="protein sequence ID" value="GIY01678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW82"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12076" checksum="C0B8FCD9478871B4" modified="2024-11-27" version="1">MPCLKQKLACFFDSQSAVYGLGRFSKSHCYIIEHAFYFMPCLKQKLAWILICFGLGRFQNPIYIIEYAFYFMPCLKQKLACFFDSHRLFMVWVDFQNPIATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PY85</accession>
    <name>A0AAV4PY85_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Neuropeptide CCHamide-1 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CCHa1-R</name>
        <name evidence="12" type="ORF">CEXT_526551</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005401">
        <property type="protein sequence ID" value="GIY02029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PY85"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008188">
        <property type="term" value="F:neuropeptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF26">
        <property type="entry name" value="NEUROPEPTIDE CCHAMIDE-1 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY02029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="204" mass="23228" checksum="BA0610FBA374EC06" modified="2024-11-27" version="1">MSLAVGDFILIVGTVPFISTIYTFESWPYGEFICKLSEFLKDVSMGVTVLTLTILSFDRYIAIVLPMKKYTGSNAKTMTFLIAFGIWFVSLILASPGAYFSFLWEVPVSKDKVIYVCYPFPKHMMPWYPRVVILTKFLLLYGIPLILIGSFYVMIAWHLITSSRNNIGQNPTHVKQLRSRTKVAKIVLAFVLIFAVCFSPVTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q1L8</accession>
    <name>A0AAV4Q1L8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_353041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005566">
        <property type="protein sequence ID" value="GIY03330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q1L8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY03330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14229" checksum="76F61B157C6262DA" modified="2024-11-27" version="1">MLSKFNLLKRLLDKFASRTGPFRLQHFFLCFRSALNLSHPRELRNLFVGGSPTKPRLPDDEPRLTLRSSLLAIKGHFVSSTKALLWRTRNAFQCLRCMVSRVDCIFCGVWDRSGWRGWGRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q233</accession>
    <name>A0AAV4Q233_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">THAP domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Thap1</name>
        <name evidence="8" type="ORF">CEXT_1931</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005613">
        <property type="protein sequence ID" value="GIY03688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q233"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.210.20">
        <property type="entry name" value="THAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052224">
        <property type="entry name" value="THAP_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006612">
        <property type="entry name" value="THAP_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038441">
        <property type="entry name" value="THAP_Znf_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46927">
        <property type="entry name" value="AGAP005574-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46927:SF3">
        <property type="entry name" value="THAP-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05485">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00692">
        <property type="entry name" value="DM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00980">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50950">
        <property type="entry name" value="ZF_THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="THAP-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY03688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="16817" checksum="0624CFE33F247EEC" modified="2024-11-27" version="1">MVNSCSAHGCKNRNTKGGNLTFHRFPLNNKHLLKLWLYQIKRGNWEPSKYSVICSEHFTKDSFIVKGQNNRRTLKSDACPTIFSIANYTEPLKKKKVAKEKNPVDVDMSEVKDESDVKLSEEELESSAEKADELPSASNPSEDVPDDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QG06</accession>
    <name>A0AAV4QG06_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_87773_1</name>
        <name evidence="1" type="ORF">CEXT_425981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006026">
        <property type="protein sequence ID" value="GIY06965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QG06"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31511">
        <property type="entry name" value="PROTEIN CBG23764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31511:SF12">
        <property type="entry name" value="RHO TERMINATION FACTOR N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="147" mass="17238" checksum="C61DC900350FAEE9" modified="2024-11-27" version="1">MPLITRSDDSYDPHLCHICTKRFLPGEIRVRDHNHWGSGRINGLAHQACNLNYRATYFIPVVIHNSRNYDNRLILKRRRHAIANNPYIAENYDETLPSNYILALDANNLYGFAMSQFLPVGNFRWLNSEELSKFFLELEEDSDIGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QI22</accession>
    <name>A0AAV4QI22_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Deoxyhypusine synthase</fullName>
            <ecNumber evidence="4">2.5.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CG8005</name>
        <name evidence="9" type="ORF">CEXT_351891</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine</text>
            <dbReference type="Rhea" id="RHEA:33299"/>
            <dbReference type="Rhea" id="RHEA-COMP:10143"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57484"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="EC" id="2.5.1.46"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01006323">
        <property type="protein sequence ID" value="GIY08974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QI22"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034038">
        <property type="term" value="F:deoxyhypusine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.910.10:FF:000010">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703:SF0">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00056884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY08974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10169" checksum="90CED14A3FA97CF9" modified="2024-11-27" version="1">MIIIGGGVVKHHICNSNLMRNGADYSVYINTANEFDGSDSGARPDEAVSWGKIKKTATPVKVYADATLVFPLIVAQTFAASYHKSKNHVKNETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QIH0</accession>
    <name>A0AAV4QIH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_450871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006331">
        <property type="protein sequence ID" value="GIY09097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QIH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14647" checksum="B8F9D839938786BF" modified="2024-11-27" version="1">MSIVLGSSYLEGMVGFVVEIFPATPLNGIRRDSYSVCRHKAFQGPPTLSRECHFRSYVASEWHFATRTLLNCSLNFRTKDDPRRYRSFLLFFFFGSSSLLFIVPCFRPGGILTVLRASSNQAKRPANRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMS4</accession>
    <name>A0AAV4QMS4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_303561</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006384">
        <property type="protein sequence ID" value="GIY09462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY09462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="402" mass="45503" checksum="357FA4D63FB0368A" modified="2024-11-27" version="1">MSSVDIVKEGDFIIVKIASVLRLAELKSNKPQYFGKRRARLFSTIGHPYGSFFEMLSDGSLIKVEKPDDLEKLPLKVDDCDQVKDNRSLTDTGESQKLTTSDIEAFKKQGLSGKEMVKKIVENSRSFQEKTAFAKEKYLRKKQRKYMSVVQILKPNVRLLAEMYYIQGPLKIGNLRIDSLSQMLAFCNITSGGKYIIMDTVNGLLTAAVLERLGTEGCAVQLHLGHFSLNTYQHIIKALNLPRTILQSLLHNIDLKNVVPLLRGMEEVPMVIDPSVADSHAKEHNTKAEEKKDHIQKVKEILRPKNMDSLLVAVKHHPANVLQLLDLLSFSRPFAIFSMYQEPLVDCYVKLKSRGDIISLNISETWLRKYQVLPERTHPCYYMSGTGGFLLTGIKVAPKNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QX15</accession>
    <name>A0AAV4QX15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_618051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006815">
        <property type="protein sequence ID" value="GIY12611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QX15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11318" checksum="7485F0D94A4F5370" modified="2024-11-27" version="1">MTSYTFLLHPFHPPPPHPLHTPESHRNQPPPYTSDTQRRKTSLAAIKWKSLLFFPPPPSPAAVVGIVHTASACDVTRRLSKSSPHGAVALPDQMDAKHRRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYG8</accession>
    <name>A0AAV4QYG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporter NIPA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NIPA2_0</name>
        <name evidence="7" type="ORF">CEXT_720861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NIPA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007099">
        <property type="protein sequence ID" value="GIY14535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF92">
        <property type="entry name" value="SPICHTHYIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY14535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15818" checksum="0FAA00DBAC8EF650" modified="2024-11-27" version="1">MLMILVTAFASSRILGEKINKYWTLAFATSLGGCLVIIVHVPKEPHIYDIETFLYMITAPMFLAYNAFLLVFTVIMIRFTIPKWGQVNSVAYTLQSAIFGSIIVVALKGVLLVFTDKFFHWVPLICVLAFEFAFCYSSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZ73</accession>
    <name>A0AAV4QZ73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_483911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006966">
        <property type="protein sequence ID" value="GIY13611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZ73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY13611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12155" checksum="54F09F7C927A9477" modified="2024-11-27" version="1">MMTEFLPDDRNKPLNNGAPKRGQPRKTKPNTRCKCVVNFFRFLWNIILGKDIDSALHIMFGFLYCVSAASFFVIELWRPRAENGTPWPYSWMVFIVMMISTFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R8C3</accession>
    <name>A0AAV4R8C3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_269081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007377">
        <property type="protein sequence ID" value="GIY16422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R8C3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY16422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15630" checksum="D86C340F04D2CD01" modified="2024-11-27" version="1">MSLTPSSKRIHTYWYVFLLFAAVISSSSYGSSLIDQYRDHLNKFNEIVQWTFSPLGSFSVEIVDPFVNSEIYVILQETIDAQPAKYIGLHCLRFFLHVEEPARCYDYYCTGHLHRCGDTVFTMLSHSAEESGENEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFA1</accession>
    <name>A0AAV4RFA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_634251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007840">
        <property type="protein sequence ID" value="GIY20140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11270" checksum="9746B8FB08011EC2" modified="2024-11-27" version="1">MVVFHVGGFYILLKFRSSLFRIDLSVCKKLVHEALRSRQETLLCFGLKLCLASSIRSFKANNRRRAPVVVCGALLGRGPASIKIDYLGLGNFWSSCPSSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFK4</accession>
    <name>A0AAV4RFK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_452911</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007861">
        <property type="protein sequence ID" value="GIY20260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY20260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15491" checksum="7BD826011D73ED75" modified="2024-11-27" version="1">MNLTPRAALFFVIDVLNDGKTTEDIKVRGYDIPKNTIIIAVLSAIHNESKYWKTPEKFIPERFIDEDGALVTKPEGWVPFSYEANSAIFNNQELGLTELLYLKHKVLDENPSEANNLIFNNQELGLNKMLYETQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RFM3</accession>
    <name>A0AAV4RFM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_108331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007704">
        <property type="protein sequence ID" value="GIY19010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RFM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14671" checksum="C73A87F0FFEC0F75" modified="2024-11-27" version="1">MVCFVALEIRKAKALHLPISFRREPHLWRITSTCLKSLSKIFLDSLTTRTISVIIDVHALFKRSSPNRRNFLSLSNRRIDVERERGMRMKNFDDVIEAAKSSDNISKNPPSISWNNLQWNSIKSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRR2</accession>
    <name>A0AAV4RRR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_719401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008424">
        <property type="protein sequence ID" value="GIY24583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9300" checksum="DDE052EFA2E286F0" modified="2024-11-27" version="1">MSREQKKGCSSREVRAPKSPVLDLKTVINSDDIKLQNSSSNTFSLFNKIAEYNIGDEHGKYLGRNVLSCVRGGLEKSVNPKMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RYG8</accession>
    <name>A0AAV4RYG8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor SOX-15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Sox15</name>
        <name evidence="2" type="ORF">CEXT_236431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008599">
        <property type="protein sequence ID" value="GIY25896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RYG8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="12344" checksum="70220426C3AA69A0" modified="2024-11-27" version="1">MHLSSLEETMAAYQQDDPGSPYPAQDAMAMMGQDVFHRSPGCDYAGSPGTSRQSGSATEYYGSPYTRAWPPQDYPVSYGVPDDHPSAGWLQDGSGKLPPQDKLCPRGYGHESGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S120</accession>
    <name>A0AAV4S120_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_30581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008767">
        <property type="protein sequence ID" value="GIY27059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S120"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY27059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="10458" checksum="DAEA41FC7F29EF20" modified="2024-11-27" version="1" fragment="single">NPFHVTVRCCSFPKLSNSTDSPAVDFPVCTPLTDTDPILAPHRTVLNAARFCTHDAHRGTSCRWTAAPQLTMFFLPALFSAANGSFANRKGKVHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7N1</accession>
    <name>A0AAV4S7N1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfotransferase 1C2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Sult1c2a</name>
        <name evidence="4" type="ORF">CEXT_556521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009109">
        <property type="protein sequence ID" value="GIY29665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7N1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY29665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="234" mass="28041" checksum="89CDD867396DE63D" modified="2024-11-27" version="1">MLGMEGITNMPRPGAFKTQIPYSYMPYSMDAKYIFVARNPKDCCVSFFHHARRQPGLCFWDGEFNDFFECFIEGDNMPYGDYFDHLLDWYPHRKDPNVFYKKYEDMKKDIKDVVLNLAKFLGKEYIEAIEKDNSVLYNIIQYSGFEYMKNKYEAIFDMDRVQKDFKQVPYGLQYMKEFVQSLNSPRSLSEVQYVYKGNVGSWKNHFSAEQNERFNKKFLEKMKGTEVLQWYPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SA45</accession>
    <name>A0AAV4SA45_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_100761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009085">
        <property type="protein sequence ID" value="GIY29516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SA45"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="96" mass="11113" checksum="CFBF0FA7C58E4353" modified="2024-11-27" version="1">MSEDERKSDSFGETFKDEAEDPALFETLRRVQVGRNMQNHLRTGNATSSEPPADLFHRMPGPRNPISFYMGADNVQQSADYFFLQRTSNTKKYIEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SQD7</accession>
    <name>A0AAV4SQD7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_695641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009807">
        <property type="protein sequence ID" value="GIY34782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SQD7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11190" checksum="1456A71A8B8EFADF" modified="2024-11-27" version="1">MTEVILRKVLHISYAGEQFNDPGIEHNTRLKPCYHQPSHHVTESFLVGFHDQQTAECLEIETSICHSSRKVVRERAVKLSVKKSFRCAQKEDGSNPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUH4</accession>
    <name>A0AAV4SUH4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein KIAA1109</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KIAA1109</name>
        <name evidence="3" type="ORF">CEXT_226311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010215">
        <property type="protein sequence ID" value="GIY37755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUH4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048488">
        <property type="term" value="P:synaptic vesicle endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033616">
        <property type="entry name" value="BLTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056742">
        <property type="entry name" value="BLTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31640:SF1">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31640">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN KIAA1109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25040">
        <property type="entry name" value="BLTP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Bridge-like lipid transfer protein family member 1 C-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY37755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="154" mass="17062" checksum="74EAC2E4BA8FE133" modified="2024-11-27" version="1">MTGCLADFSLYIFHPYGGAKKKAGGTKEGETSPLSTSERKDSLSLQVEFVKVNISRSRKINLSHVDPVASIQKLGKSFDSGGALIRFSAICDIGSASFKYDMRRLTEILAFPKAWYRRSIARRMFLGDQSTGALYSDQGKLEKKISYSLKSIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SY07</accession>
    <name>A0AAV4SY07_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_781501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010273">
        <property type="protein sequence ID" value="GIY38219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SY07"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7605" checksum="7FD3097F3E17DFF6" modified="2024-11-27" version="1" fragment="single">ASGEVIKGGPLCMRCAIKRKFRPRLYIDPLHDYAHRSMVSLVGPLPRDPPLDPDPEPVNAAVFYVVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TH70</accession>
    <name>A0AAV4TH70_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_512471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011196">
        <property type="protein sequence ID" value="GIY44796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TH70"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="12071" checksum="15272DD4A6D7496F" modified="2024-11-27" version="1">MDWFELNVIDVTGLVLLIGFVGKKMKESGFDWTDFEWNQRDPFEVELMGYGCMLFMIYVHLFMIFIRWQPIFTLLITGIIGDAIKTHLNSWDAAKAKLSFLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJ29</accession>
    <name>A0AAV4TJ29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_771421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011370">
        <property type="protein sequence ID" value="GIY46129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJ29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8388" checksum="CB7A03C176DBAB7D" modified="2024-11-27" version="1">MPCHLQEGFGWQTVQVCQSFLFAEFRVWLMDCFDPQIDCKLVDIAHILVESEPLIYENPENSDLYKDYNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJK9</accession>
    <name>A0AAV4TJK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_750681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011219">
        <property type="protein sequence ID" value="GIY44960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY44960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10405" checksum="C7C2960F3A506B4A" modified="2024-11-27" version="1">MKFIANKSRISPLKQIAIPLLELCGAVLHVKLIHKVKDALRIDFASAHLWSDSTIEPSKKENLLTLDEVEAAETLAIINEQRSLKNNKAMICN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TLP5</accession>
    <name>A0AAV4TLP5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PEHE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_160276_1</name>
        <name evidence="3" type="ORF">CEXT_551721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011208">
        <property type="protein sequence ID" value="GIY44883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TLP5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072487">
        <property type="term" value="C:MSL complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026711">
        <property type="entry name" value="Msl-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029332">
        <property type="entry name" value="PEHE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21656:SF2">
        <property type="entry name" value="MALE-SPECIFIC LETHAL 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21656">
        <property type="entry name" value="MALE-SPECIFIC LETHAL-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01300">
        <property type="entry name" value="PEHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEHE" evidence="2">
        <location>
            <begin position="341"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY44883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="456" mass="51658" checksum="F11CD6BFC894B241" modified="2024-11-27" version="1">MKPGIVDADRFKVDGRQSVNGRKISNNSLVLNGADENLNYAAEDESVVRQVILAAAYHDHISCTKSANLCQKVDGAREGREALPCETDHIYANCSESKNKSHTSTVPSKNKNKKLTIENTNLRTMLITDLDMISQLREELEQKKEIFDHREETEMLKACLQHRERAMCLLYRNYSKSDKDNANNSGLKNGIIENGNVLANGSSTVENVNLSRHPNINTPATSLATRYFGRRSKTVPSRALKRRYMGPPKSLPTKKTIVKVESSTASISSASEVHDVDQQEIQGPTQLQENGTTEAGIRRVRKRRGRKPKKVPIKTDYLTTDKAYFVPDFRSPTHSFSSSQIDVPSWRLKPVTSFYQMEEQRWDAQRSRDTKTMKKKRSRNKENSEQRMSHSFQPDPLHIEYIEVTEQLPVMAFGHPIPLFAPCEFSLPWLCEDNLVKDPVVKAKRGRPCSTGPKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNB5</accession>
    <name>A0AAV4TNB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_80421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0488 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011649">
        <property type="protein sequence ID" value="GIY47925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029274">
        <property type="entry name" value="DUF4615"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13602">
        <property type="entry name" value="UPF0488 PROTEIN C8ORF33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13602:SF2">
        <property type="entry name" value="UPF0488 PROTEIN C8ORF33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15393">
        <property type="entry name" value="DUF4615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY47925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15644" checksum="9EEB3C3ACCD21FEA" modified="2024-11-27" version="1">MASKKNMGPKNDPAFEDELFWCQEYLELKLLQKLSLKQTQLLQQALKTLKSSKSSYIKKRQVMRNTCGNYRKDMEEEMEASEKRLENIKLEKDDYPEYSKIVRIRKSTNKEHSEESHSNLFQFNFPEPETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TPN4</accession>
    <name>A0AAV4TPN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_187721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011723">
        <property type="protein sequence ID" value="GIY48538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TPN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY48538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="21871" checksum="64D1E508BAB9F0C5" modified="2024-11-27" version="1">MGRISGVCFKDGILSSLSFPFSSSYWDSIKDDDIHHDVLGDDEQAHVHDGGDHNEGVLGVDDHDEDVLGYHVHDDVLGDADHDEDVLGDDVHDDVLGDDKQTHVHDGVDHDEDVLGDDVHDDVLDDDKQAHVHDGVDHDEDVLGDDVHDDVLDDDKQDHVHDGVDHDEVVLDSDIHVLPHDGDDLDDGVHQDEVHDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TQT6</accession>
    <name>A0AAV4TQT6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_81531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011585">
        <property type="protein sequence ID" value="GIY47491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TQT6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8845" checksum="B28BE5C5DE40A6A5" modified="2024-11-27" version="1">MVLVTVPRMTYPHMENLSTVCHYKRLYPCHENKNNLFERWLSLLGLDIIDKFLLSVTTRSLENIKSSKMCENKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TR56</accession>
    <name>A0AAV4TR56_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011794">
        <property type="protein sequence ID" value="GIY49078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TR56"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="14398" checksum="F3BE05A62DE0E627" modified="2024-11-27" version="1">MATRRAPTPSTTSTVGPDEWTIFADGHGFRATVKTNEPGTAASAPAAAPHCQPLRRTRRPVINHIAPAATVVGHAAPMAIAAPVAYGGAFGHGAAIGYGAGVGMGMDTELALVWDTELALVWDTELALVWGYGVGVGRMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS49</accession>
    <name>A0AAV4TS49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_372681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011799">
        <property type="protein sequence ID" value="GIY49125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY49125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9995" checksum="A13E67983A418446" modified="2024-11-27" version="1">MAVKKFSRDTSCGMERQVHPRRLTDQSFRKMIIEKASATEHALSLNKREKNRQYRLEADLIVGRNLFCMLFGLYGIINFHYTANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TVJ8</accession>
    <name>A0AAV4TVJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_37931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011806">
        <property type="protein sequence ID" value="GIY49194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TVJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY49194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8823" checksum="3AE92A13FBDE8B89" modified="2024-11-27" version="1">MRMVVFENDNGFSLSSWVNWRVGKADLIAFNREGNVRNHRERIAKEFSNKWRAASERIGAELRLFPLGGAELKIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZ72</accession>
    <name>A0AAV4TZ72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_188191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012010">
        <property type="protein sequence ID" value="GIY50686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZ72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="7936" checksum="599BC5387BDE44C4" modified="2024-11-27" version="1">MAHRVSKCKKPHIIIVERKLSFTVEMVNIMADVSARKLLSSDGKLLEGDSFINSFMDEVTAFFFGCFYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U2C6</accession>
    <name>A0AAV4U2C6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_260011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012173">
        <property type="protein sequence ID" value="GIY51887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U2C6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY51887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9209" checksum="E2171B1C27871D69" modified="2024-11-27" version="1">MSGDSLTFISSLSLFYSRHAPTTPPARPISRIIPIRVNIPRRGKTRPSSHYSANHIDLSPASQWRSPVIGGEEHLAERGGHQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6B4</accession>
    <name>A0AAV4U6B4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_389672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012339">
        <property type="protein sequence ID" value="GIY53270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6B4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="156" mass="17268" checksum="5148D86801FC58E7" modified="2024-11-27" version="1">MSIHAGVSSMMEMEVSPDDSQGPFQGRISPAAPEQHQQPQSPEAIYSTLQSIESEISNYHEELATYQICARLKSTQQTPGMMDSFQSAMELVERKISIHLQKVRLIGSCPKFNCNMHSLSTENLGNPSATFQSASNNLKRAPDSDNDGFQLNDLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHX8</accession>
    <name>A0AAV4UHX8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_458731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012896">
        <property type="protein sequence ID" value="GIY57369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHX8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33964:SF1">
        <property type="entry name" value="RE45066P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33964">
        <property type="entry name" value="RE45066P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12029" checksum="7040AC31F3CADA30" modified="2024-11-27" version="1">MRDCMIDMQMTVEKVSESKFDKRVGTLCCGFRRFLECGEKLTERKCGREAVEMGQTIAELAVTELPNVVCHSFDPNSNSCKALLPPKGSTPKGTQSSSQLARLLATALGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULB2</accession>
    <name>A0AAV4ULB2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_456831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013077">
        <property type="protein sequence ID" value="GIY58554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULB2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11322" checksum="34C89BD4ECB461AE" modified="2024-11-27" version="1">MNGYGIRREKFFSNFPQVAMLMTLIHSQSRYFLEPIYSAVFLNLPSLVKGGAINTAPGTDCGVFLFPWRRSSDVWVLDRLVASEIVCEVLTILHVLVRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UN73</accession>
    <name>A0AAV4UN73_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_169861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013179">
        <property type="protein sequence ID" value="GIY59223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UN73"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12841" checksum="07C065C3F43349E3" modified="2024-11-27" version="1">MVCLSRINFITRSTSYTSDNRVQIIYAAWGLPVRAPPVIKVAEVMERQPREPRNRRKGIFHPDRCSSCEMERVINSSSPIKSGISGHALIKGDGYEYFSILEPPGPARLPPTASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URA8</accession>
    <name>A0AAV4URA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S15a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS15A</name>
        <name evidence="5" type="ORF">CEXT_326251</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013328">
        <property type="protein sequence ID" value="GIY60426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY60426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10302" checksum="821D66CA663F535A" modified="2024-11-27" version="1">MMKHGYIGEFEIVDDHRAGKIVVNLTGRLNKCGVISPRFDVQLRDLEKWTRNLLPSRQFGFLVLSTSGGIMDHEEARRKHLGGKILGFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZN9</accession>
    <name>A0AAV4UZN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_268351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013737">
        <property type="protein sequence ID" value="GIY63426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="76" mass="8649" checksum="C7AC3B38827D92A2" modified="2024-11-27" version="1">MSQVRRRPLHQKNDMTTCMTTCKMNQPPVSTVASKVSSPHGEAVPCFPRLQASLPLELFYPLKTLQLLSCRRAHHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V045</accession>
    <name>A0AAV4V045_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_503421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013763">
        <property type="protein sequence ID" value="GIY63610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V045"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="590" mass="66964" checksum="4F4FBE346D226FAD" modified="2024-11-27" version="1">MLPLKKTQNDKLVYLGDKIFNYPNNRSLKIGTCYRNLAGTCYRSLSDIHYRTAVDDIEILLILPIEVLRTLAIEVLRTLAIKLLLHATETLLTLATEVLGDIHYRTAVDDIEILLTLAIEVLRTLAIEVLRTLAIKLLLLATETLLTLATEVLDTCYRSLKDTCYQTAATCYRNFADTCYRSLSDIHYRTAVDDIEILLTLAIEVLRTLAIEVLRTLAIKLLLLATETLLTLATEDTCYRSLKDTCYQTAATCYRNFADTCYRSLSDIHYRTSVEDIEILLTLAIEVLRTLAIEVLRTLAIKLLLLATETLLTLATEDTCYRSLKDTCYQTAATCYRNFADTCWHRSLSDIHYRTAVDDIEILLTLAIEVLRTLAIEVLRTLAIKLLLLATETLLTFATEVFDIHYRTAVDDIEILLTLAIEVLRTLAVEVLRTLAIKLLLLAIETLLTLATEVLDTCYRSLKDTCYQTAATCYRNFADTCYRSLSDIHYRTAVEDIEILLTLAIEVFKDTCYRSLKDTCYQTAATCYRNFADTCYRSLSDIHYRTAVEDIEILLALPIEVLRTLAIEVLRTLAIKLLLLATETLTLAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V4C2</accession>
    <name>A0AAV4V4C2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_65371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013892">
        <property type="protein sequence ID" value="GIY64534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V4C2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13481" checksum="2C23B89763F45883" modified="2024-11-27" version="1">MPEFNIFNGHKYLGYFKGFFKERDRKKKTNLLKFQTILTLDRIPPPNEKPVVGGAAEWKEEDYRLPDDYACERVRTAQETEGHQHTRMSRYDHSAGFHPPLPFFFFATRNRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V661</accession>
    <name>A0AAV4V661_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_567331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014010">
        <property type="protein sequence ID" value="GIY65606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V661"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY65606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12009" checksum="85E6BBA55F5104BE" modified="2024-11-27" version="1">MITDFKLTLVINNGKIHAITIQNRIGELAIKSWRSASCAVTLVTSVPFGSFSFHMPHNHNILESRWIHVLIHILHFHHKGSLGFQRRITPIPGSYGHIVQLRGLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V675</accession>
    <name>A0AAV4V675_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">THAP-type domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AVEN_176319_1</name>
        <name evidence="7" type="ORF">CEXT_659261</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013998">
        <property type="protein sequence ID" value="GIY65514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V675"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052224">
        <property type="entry name" value="THAP_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006612">
        <property type="entry name" value="THAP_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46927">
        <property type="entry name" value="AGAP005574-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46927:SF3">
        <property type="entry name" value="THAP-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05485">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50950">
        <property type="entry name" value="ZF_THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="THAP-type" evidence="6">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY65514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="35203" checksum="46137EF402F44204" modified="2024-11-27" version="1">MPTGGDSLEFSWRVFCSMMVKKCCVPCCRSNYDPTVYISCFQFPKEEDRRNLWLKKINQKDYSPSKNAVVRIKHFREKFVITEHHAVRDDGSVLTVKRIYPNLTLYAYPSIFPNQPAYLSSDPVSKEKLPSERRNEILNWDGKKFTDWCLKDIIKTFDDFPKEFPTKLTKEWLFIVQEDDVLFYKLNICNGQAPRIKVSFAVDRNLSVSAWHGEIALSNKSLHILQGNKCDRWTKFDCLLSTFENYEEKNVCIEDKFNYTLNFLQVVRKRKEKEEKLRIDERVLCFYEKGQGAIDILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VNN9</accession>
    <name>A0AAV4VNN9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_614621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014853">
        <property type="protein sequence ID" value="GIY71753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VNN9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY71753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="104" mass="12661" checksum="0AE9EA98B006E398" modified="2024-11-27" version="1">MVPIREDKIEKPRLVSIHIRPCELEPSRRIPGMNVLRNIDGPKQKERGKRKNRSQHIYHPLRDRKFQKLLERSRNHYQRQSPKIEKYQYVNGPLTKVTWRMTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VQP8</accession>
    <name>A0AAV4VQP8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_678261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014949">
        <property type="protein sequence ID" value="GIY72458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VQP8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="202" mass="22716" checksum="68CFEAC191ED391F" modified="2024-11-27" version="1">MREQLQLYVLAHEFTKLIDHFGISKLSSNYNMVPPQYDIGGVATRSLPALSGLALFHENKMKQYYSTEITKHIPNLLIRSIAQIDGGEVNLLFLVILSFLKAITAQNHRRYMKATNPQIFRRNCFLPSFPNDYQIGVAQPLVLLCITAGVTIAELPGCYNSCCRSPTSINSRACIIRGVVLKKNGTFRVQEGRRGHPFAVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWX7</accession>
    <name>A0AAV4VWX7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adult-specific rigid cuticular protein 12.6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_627601</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the rigid cuticle of the spider.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015209">
        <property type="protein sequence ID" value="GIY74375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWX7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY74375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="10763" checksum="164AE56D8BAEEEBD" modified="2024-11-27" version="1">MAADMGMNIAGGAYNFGYQTGDAGGHSRVESGSAGNVAGSYSYIDANGDRRTVQYSAGPGGYQASGDIGVDRRTAAAAAALAAMAPKPPSRSTSPSCTLVQPCPHCTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4Q4</accession>
    <name>A0AAV4W4Q4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate 9-O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Casd1</name>
        <name evidence="2" type="ORF">CEXT_53091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015615">
        <property type="protein sequence ID" value="GIY77378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4Q4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12698" checksum="730BC63603148A33" modified="2024-11-27" version="1">MTQVSEWERNNVWERSARNRKKHINSRNAKILAVSIVIGFIGYHGILHLTSGIDSCKWLLSDGRLSRFRVWQPYGCMMHSYSSGDTLLNWESETHLRHLYPRLLKTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W6K9</accession>
    <name>A0AAV4W6K9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015750">
        <property type="protein sequence ID" value="GIY78372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W6K9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14490" checksum="4D60DFFA526D0A55" modified="2024-11-27" version="1">MGCNTLYVFPITENFCSQPKASVVRTVLKRNILSSQCPRNQKWADGLGCWPMSCQKRHFCALLSSEFPQTSRTHIDFLFWNFCTRPKASVVRTVLKGNILSSQCARNQKCADGLSAGPCLAKKDIFVHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W7M4</accession>
    <name>A0AAV4W7M4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_451641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015696">
        <property type="protein sequence ID" value="GIY77909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W7M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY77909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9460" checksum="75B219A3F5D613D0" modified="2024-11-27" version="1">MVGVYPGTGSRRTKERIKKNVAGIGGKPDAPPVVYVFIHFSAVGNTESAPSRWFQNRNGTFYDFHRMSRTNFTTRAHEITALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WDH3</accession>
    <name>A0AAV4WDH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_38211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015939">
        <property type="protein sequence ID" value="GIY79864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WDH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="9456" checksum="7F039121804AA99B" modified="2024-11-27" version="1">MWPRAYRQIGGRLLGRMPEGGWNPPIQRTQMRLDDFVENSTFLIYFKPAFMRQDLMYQNLTVLQQKSFKDSLEKAKHAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WHZ3</accession>
    <name>A0AAV4WHZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RILP-like protein homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Rilpl</name>
        <name evidence="8" type="ORF">CEXT_674842</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016249">
        <property type="protein sequence ID" value="GIY82450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WHZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14445">
        <property type="entry name" value="RILP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051241">
        <property type="entry name" value="DZIP_RILPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034743">
        <property type="entry name" value="RH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034744">
        <property type="entry name" value="RH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021563">
        <property type="entry name" value="RILP_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21502:SF4">
        <property type="entry name" value="RILP-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21502">
        <property type="entry name" value="ZINC FINGER PROTEIN DZIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09744">
        <property type="entry name" value="RH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11461">
        <property type="entry name" value="RILP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161256">
        <property type="entry name" value="RILP dimerisation region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51776">
        <property type="entry name" value="RH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51777">
        <property type="entry name" value="RH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RH1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="RH2" evidence="7">
        <location>
            <begin position="266"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY82450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="370" mass="43104" checksum="D0072E671B6BCFE7" modified="2024-11-27" version="1">MDKMVDSQIFVCDVYDLAAEIGKEFEKLIDVCGSDTIRELMTKVILTLEYLESSTAGIDSLQSELNDVKVKVQQLEYEKLERAEFRNKLDQELEVIEENWRKETSHLNSLVVKLQEENKRLSAIISEKDKHTPSDCKAFLSDEELLVVQKLKELTEQHRKQLILKDKELLEKSNEIEKMQLELDRLSKVNKELSHRNRYLQKQMYMLVEEKSDLQANMQDKQKECMDLVGKLNLAVKENMDLSSLEDQKKFDLHGKLVISLDDPNRPRFTLDELRHILFERNDLKAKISDLEDELSLHKPKSIPSSTSLTTISVESEDEDPPVQGPINKEPEDKLYPEKKKLGIRRFFHFLRRISVDSPVPLVPFSASHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WLB6</accession>
    <name>A0AAV4WLB6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase family 92 protein</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVEN_18783_1</name>
        <name evidence="9" type="ORF">CEXT_440571</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="BPLR01016329">
        <property type="protein sequence ID" value="GIY83049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WLB6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF40">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY83049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="249" mass="29369" checksum="5EB281FC3F393C6C" modified="2024-11-27" version="1">MSDGKTMDARVVRKVMNEHWKLRYSSCFLSCEVPKNTLPPLKVLVSLNRNFTFSAMLPVHQNKENIASPRGDLAVCVKPLHYSYDRATWLLEFIEFHRILGVEHFFFYNHTVGPNVDVLLRHYISQNIVTVLPWSLPVLSQKEIRTEAIFSSLNDCVFRTMYLFHYVILLDFDEYIIPREHESYLDMLNQLEEDNKHIRGKPGSFVFKNTFFYLYWENDTIAYGVEPENHLNGYLTSSPSTKREDYRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X040</accession>
    <name>A0AAV4X040_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_654491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016902">
        <property type="protein sequence ID" value="GIY87184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X040"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY87184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9836" checksum="C8AA7BF3664B5299" modified="2024-11-27" version="1">MGMINHHCGLAKNLQTWTCRHIRAVVSIVEKSRKFGVKVDKKGIGWVNIYHNDQLKIRKDCENDHECLTKYLQTFLGMLMYTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X050</accession>
    <name>A0AAV4X050_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acylneuraminate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CMAS</name>
        <name evidence="1" type="ORF">CEXT_233991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017074">
        <property type="protein sequence ID" value="GIY88536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X050"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008781">
        <property type="term" value="F:N-acylneuraminate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02513">
        <property type="entry name" value="CMP-NeuAc_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050793">
        <property type="entry name" value="CMP-NeuNAc_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21485">
        <property type="entry name" value="HAD SUPERFAMILY MEMBERS CMAS AND KDSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21485:SF3">
        <property type="entry name" value="N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="22969" checksum="1EEF868985E8DB90" modified="2024-11-27" version="1">MGLHPMLDCKKLTSVWVSTDDTEIAEVALRYGAQVHYRDKKSAKDVSSSLVGVQDFLHKHPEISIIALVQCTSPCLLPMYLDRACEMMLDQNYDSVFSVVRQKKLRWKEVKQGESTEALNFNPRQRPRQQDWDGELVESGHFYVSRASLIRENLCGYVEIPEELCIEIDSETDWIIAEKLLELYGYKKNVNELKEYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XC67</accession>
    <name>A0AAV4XC67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_512101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017408">
        <property type="protein sequence ID" value="GIY91384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XC67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15701" checksum="C2AFEDF09E6706D2" modified="2024-11-27" version="1">MFPGVFHSTLNKQLFSGRADKAGSCQPNQQLEMKKVRSLGLHRGRTSKRFLNVIAFFKSVCDCPNSLYHKAEKKLYVRNERVQKEFRNISWIERVKRLQTRSYSDFKRGCLNRRLTAFNRRGQPGSSTQGSSGSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCU4</accession>
    <name>A0AAV4XCU4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_253921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017514">
        <property type="protein sequence ID" value="GIY92258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCU4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="22620" checksum="3E0CF0C5DC0218A4" modified="2024-11-27" version="1">MSQNENQYLMNRNDSQRHKTTPTESRLLKTKTQQWYLQELFLKYFIDYKAKNTMKRNTTTERQRKANKNVQNNKDNCGGQAFDTSSLTDDWSTLRSNIHRQRTKLLLYTRFKRRCPAFCFTGVSIYWWHHVFMKGKAICLFIPRTVWIRRGASITLSDGVNISSRIDVTVASLTLLDFTGFSFSAQFLGGLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD75</accession>
    <name>A0AAV4XD75_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear transcription factor Y subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NFYB</name>
        <name evidence="7" type="ORF">CEXT_504841</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000176">
        <property type="protein sequence ID" value="GIY92653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD75"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043349284" evidence="5">
        <location>
            <begin position="22"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="6">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY92653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="208" mass="23200" checksum="32552268E6BCA8DC" modified="2024-11-27" version="1" fragment="single">FNIYFCLLLISFLLFKITMEGNDGTGLDESFLASGQYIVHAEDTDEALGISGDSMDATEKDGRPLREQDRFLPIANVARIMKLALPASGKIAKDAKECVQDDRCHQEKRKTINGEDILFAMSTLGFDNYVEPLKLYLQKYRESIKGEKSISIATATDSSIDELEDAAYSSQTISTNMMTDQSGQNVIYTTTYPSQVSSFYLKQDILPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF86</accession>
    <name>A0AAV4XF86_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_445281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017649">
        <property type="protein sequence ID" value="GIY93302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF86"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="149" mass="17363" checksum="0895A1A34F5B23B0" modified="2024-11-27" version="1">MKTLRLKFLQMLLYKYGLEPEFSRIWNSSAHVDGNKRDVPPAGIGRDLFEKKMKENKCRSSRTFLKEGCDLILNYSRSFIKEFGAFYLPTGQDLDEFQSSSADATNLLFIFLSRKNIPRYFVQESECGCNRNCQRSLELVSRPRVNRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG87</accession>
    <name>A0AAV4XG87_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_360681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017756">
        <property type="protein sequence ID" value="GIY94192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG87"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="15179" checksum="A961FB6950FCAECE" modified="2024-11-27" version="1">MFIDKYRVFGQGISHGYKGFVHRLCTVVQRLLTLPRIYKKTRILYNSESVKMQRNICISTFQNINAERHRFCPFGKFANQYSMMINFFTSYFRGCYFSRSTFGVKEHEETTDCKMAYDGFYDDSQFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XH02</accession>
    <name>A0AAV4XH02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_563871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017767">
        <property type="protein sequence ID" value="GIY94300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XH02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14613" checksum="56CCAD1EFB045C22" modified="2024-11-27" version="1">METMGLWVNGVVYAIPRTPGKWAHKKCQTRLENYVETNNEERHLSNLISNSARRHAQLKRPFSRMLVLQQQQRSVRPVANSFRVVQVGGGYSNGACLAIPWHPGKWAHRAIESGRNAFFERLCNNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHL7</accession>
    <name>A0AAV4XHL7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein phosphatase 1 regulatory subunit 37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ppp1r37</name>
        <name evidence="1" type="ORF">CEXT_562631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017723">
        <property type="protein sequence ID" value="GIY93938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHL7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="361" mass="39379" checksum="DB2AA4D82103E60C" modified="2024-11-27" version="1">MKSLPKGMPCVSRTLTSARALRRLNLGSNALTSAGVLELKQSFICNRTIEILELENAKITSEDGLTALSEAVSKNLNIVSLKVDPTSMDLSEPIKDRQERLQEINKCCQRNKEAKSSLPPQDAQLSFLFNGIFSHVLPTTLPADITPKGGDTPPKARKGRFRVSVVVQDSIAALPKPPVDVSRSMSLDASYCSFGSHDLVGQMAKDSADNIRRQSVNVPDALRLVNASDGLISKPVKSDNLVLDRVKWLEGLEMPSEKICDICSCKDNSEVFHSEEVKEKKEGLSLSLSQIADETPEGETKVRRSSSPTISKARPLCAARLTVSNAARSLKVLICVLQCHSLPQGCTKVLIFLILKSLKFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XKY8</accession>
    <name>A0AAV4XKY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_282991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017900">
        <property type="protein sequence ID" value="GIY95349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XKY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY95349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9619" checksum="7D2DE5E9EBAB5E60" modified="2024-11-27" version="1">MAKAPEKESKNQRACGDDSDEESENLEESPCGRWVKKKRRDVWQKVSVSTDLTAIESGGKEHLSNPFLFLYLLILTDAISENGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XR57</accession>
    <name>A0AAV4XR57_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_48901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000632">
        <property type="protein sequence ID" value="GIY96183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XR57"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8743" checksum="D9AE1BDF55A57542" modified="2024-11-27" version="1">MTIDVYLAPASGPCRAVLMAAKYLGVDANQKTVNLMTGEQMKPDYVKQLTSHNVSSCSACNCDFNCIKLKKLISTSILER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSZ5</accession>
    <name>A0AAV4XSZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_8291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018201">
        <property type="protein sequence ID" value="GIY97708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="6546" checksum="A59789141D1ACB77" modified="2024-11-27" version="1" fragment="single">KQKEYQHELRNRHSKRMIPATAIDGKKPSDDTITAGQKELVRLPHIFHYTTFRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWE8</accession>
    <name>A0AAV4XWE8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_493351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018270">
        <property type="protein sequence ID" value="GIY98220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWE8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13354" checksum="5BF901B80F36808F" modified="2024-11-27" version="1">MLHAVTSIPRVTKKERTGNSCSSIFQVQTLLKPGHYSRNQYVPDPLNSLFCARDPARDYLIDLWPPCAVLPCEVCLWGQWIISRSSGPNRSQSMGGEKFCSLGKGGRLKESEGGAWLRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y172</accession>
    <name>A0AAV4Y172_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_773771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018525">
        <property type="protein sequence ID" value="GIZ00254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y172"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="133" mass="15337" checksum="75FE94655604ECAC" modified="2024-11-27" version="1">MHTEFFPIQKSSKKKETADEIQNFFCFSRRHFSRRDIFPDTPDKNFSEMYDASLSPHQPDKLTFHAIKRTLKNLSGKSQISCSADHKFSIRVSFRKTTTLVTSEKHETSDIQQPFSNATILHPRKALMGSVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1X6</accession>
    <name>A0AAV4Y1X6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_631441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018651">
        <property type="protein sequence ID" value="GIZ01302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1X6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14090" checksum="21F556FA5E3E3039" modified="2024-11-27" version="1">MDYFKSFTIHGTPESFSKKQAKEGAYFTSLRNHVTGICMQRRIKSFPSSGSERGVFNFGSLAMKGRGTVGNSFNDDRFTSSLKRGGVERFKSLDRKLGFHCPGRLASPASRKEKVSLLSLSLSVRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y1Z5</accession>
    <name>A0AAV4Y1Z5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glutamate receptor ionotropic, kainate 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GRIK2</name>
        <name evidence="14" type="ORF">CEXT_717371</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001250">
        <property type="protein sequence ID" value="GIZ01088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y1Z5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000105">
        <property type="entry name" value="Eye-enriched kainate receptor, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="13">
        <location>
            <begin position="72"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIZ01088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="327" mass="36997" checksum="324DA12ABC069EF8" modified="2024-11-27" version="1">MAISPENKGLECDRLHEAIHEPGHRHPLQAAQEHARETLLLHEPPGGGHLAVRAGRLHPGQLHHVHRGQVQPLRMAEPHPCVTECDVMENQFSLGNSFWFTIVTLMHQGCDLNPKATSTRIIGAIWWFFTLIMISSYTANLAAFLTVERMITPIESVEDLAEQSKISYGTLEGGSTMTFFRVGSFPPSLLFYVTFLRRTRPTWPLYRRAHDNANRKCRGPGGAEQDLVRHAGRRFHHDILQGGFLSSLFVILCHFPLHGQPGRLPYRRAHDKANRKCRGPGGAEQDLVRHAGRRFHHDILQGGFLSSLFVILCHFRHTRPTWSPSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y2B6</accession>
    <name>A0AAV4Y2B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_203711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001279">
        <property type="protein sequence ID" value="GIZ01293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y2B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10887" checksum="C0C97AA7214B6959" modified="2024-11-27" version="1">MPKKRIRRDLDFDHNVGSRGHVQIVPGHYFYCSFFPFIFLPGRTTQRRISIKKKYLSDQNVFFRINANSTHSNMDQSFCICILRPSARFVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y388</accession>
    <name>A0AAV4Y388_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_127311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001220">
        <property type="protein sequence ID" value="GIZ00890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y388"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ00890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13839" checksum="0CCD8A07933E90F1" modified="2024-11-27" version="1">MEKKKVSGCLFDHPFLTSIRGDKAGKCLSIQIWRKKSGHPRSKTVLMPQKTFILPSTKHLLNDLDIAQLLQYSSSSLGRYVILLHGRPGFLPGDVCFSGNRTKDRVNEWKTRALKKRNTGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6Q8</accession>
    <name>A0AAV4Y6Q8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_538661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018730">
        <property type="protein sequence ID" value="GIZ01839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6Q8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="10991" checksum="32A78F44E2B4C485" modified="2024-11-27" version="1">MNRKGKKSNKSNEMLSLNKALHWRVSDVTEKTVGNPSIHPSTTNGSTNTPGHQTPWRGGGSNRKKQDVILSLKGSVILTAGMKAQFLAKLLVVAILMESHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7L4</accession>
    <name>A0AAV4Y7L4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_707481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001537">
        <property type="protein sequence ID" value="GIZ02993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7L4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ02993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8015" checksum="E33457B327FEC714" modified="2024-11-27" version="1">MTELCSIFTYPKNGREFPDDEIGDSCYLGFKRNDCSWKFSGLFGLRNENDLAIVKLFTATAIRIAIWDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBS5</accession>
    <name>A0AAV4YBS5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_29961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019109">
        <property type="protein sequence ID" value="GIZ04593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBS5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9086" checksum="81C8B0AA9BF12166" modified="2024-11-27" version="1">MLGYNHEFLCSLVSRLNKDSLVMANAVKATFRSHSLVICISLDCHVSVLNLSLTWLNNPIVKNQIFSDPLSRIARHLRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCI1</accession>
    <name>A0AAV4YCI1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_214821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001784">
        <property type="protein sequence ID" value="GIZ04718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCI1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9319" checksum="C6165C5F8B87A21B" modified="2024-11-27" version="1">MFSKVWAFDAILNPKLNFSLRPEDRSFFFCRTVINTAKEKGLGSKGTFLLTHRARESEIENDGFSCPTFPDTSPFASQCTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M4Q9</accession>
    <name>A0AAV4M4Q9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_464041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019381">
        <property type="protein sequence ID" value="GIX67195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M4Q9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16751" checksum="86B3DC3083B63F94" modified="2024-11-27" version="1">MTYYTSILRHAISILEKNPVFLFPGQPTVESIKENQQERLLFSVTCDASIPELHILLLFGLGSSPDEGHPEQQGQQMCGFQHRSIDLGGWRAAIGSEDDCQHAIVTSVSWAGWVINIERKNASGDQGGSNSSRSAALQSVGVTPWKEEKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MD32</accession>
    <name>A0AAV4MD32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Vps13_3</name>
        <name evidence="2" type="ORF">CEXT_489701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019516">
        <property type="protein sequence ID" value="GIX68714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MD32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="250" mass="28020" checksum="0790CE4739014D51" modified="2024-11-27" version="1">MIDKAYDKFDISIQNIEILLTDSGNDWKDFIGKLDDPHHLLYPLTISIDFHQSIVTIDPRMPKMKIVGVLPLLDIGISDTQMFKLVKIGTSIPLPESEPSAESLPGPTIFSFTVSRSTKEEDIDILKLAFHNFGAGLVMRTFDMTADVYLGGIVLHNSEFLTPQGKPLKMISSVTKDSDEPLFSLNYLSVNKKAPDFETLYNSTLQTISANFRAIDFILHQEAILSLMDFSNSILSNVQPTSEKHQQQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDC3</accession>
    <name>A0AAV4MDC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_180751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019641">
        <property type="protein sequence ID" value="GIX70009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX70009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="14700" checksum="279DBAB9994009EB" modified="2024-11-27" version="1">MNETETLTIPIKCSNHVSVNSVEFRTPVPISLSTVEGGTQERGLQASHPLGAHLPVTEKNPPPKKKKRRERRGNDTCRMCVPWCCSKMSMAIDEDDRDRREPLEDTNIESVTQVNSSSIEFSFRSSPMIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MF83</accession>
    <name>A0AAV4MF83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVEN_17050_1</name>
        <name evidence="4" type="ORF">CEXT_527371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002181">
        <property type="protein sequence ID" value="GIX71018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MF83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051230">
        <property type="entry name" value="APP-Binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12345:SF11">
        <property type="entry name" value="FI13065P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12345">
        <property type="entry name" value="SYNTENIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="70"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="379"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX71018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="638" mass="70937" checksum="0515C51466AC9ED0" modified="2024-11-27" version="1">MSRESSSDSVAMQSASASTSSSEMEQRTEATAAVTEDSNNNTSLLDRERVSEAASSETPNASQHSPAVREIHKNSWLKKMPCIDKWSGKFPKAQKLEKFWVVFCVHDDKEAFLEFYENRRSAYSHMPLSNISLSKCLHISPTIVAQGNDHEFVITLDNQVIRLAASTNEQMLEWMDTLSTKLRELGVLEPKDNLYSKEPITTRPLSHQHSASGLSLESQSRADFSRLSIRDPNSPLPPVPSTLAQTSESIESTALSSTVIYVRKPIIPKCVPTIPSPIEVESRTTSIPNTPSSEQTSLYEPLFYSSTSSNISLGIRNPNYENPPYPQRHIVCKPTPALPPRPSSDFHRAPPLAVGENSNVHSPIRASNLGNLTSASDPSLHASTQQQQSSSNVSAQSSSSASPVALSRQHSHLEPASSVSERSNHPPLVERHPHNGMRQQSSSSFKNGSIPVDENGNPFLCGKHKYRNFRWQAGNKKSILYCTIHFMLATAFSALQAIGFFPCKTLIEQLKLQPSTVEFIVRRVPYAKILAVKREYEGQDLGIVREGGTAEKSNQVAWLFDKAYLRKASSLDGNSFCNWVLTEINHRPLNLFFKDNEVQDRLNAVGLDISLLVQPIELVKTLKKQLKTIRGYKDYIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MIW5</accession>
    <name>A0AAV4MIW5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carnitine O-palmitoyltransferase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpt2</name>
        <name evidence="3" type="ORF">CEXT_505671</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019830">
        <property type="protein sequence ID" value="GIX72263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MIW5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004095">
        <property type="term" value="F:carnitine O-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF16">
        <property type="entry name" value="CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX72263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="244" mass="27213" checksum="6FDA6BCE30E8B02A" modified="2024-11-27" version="1">MIFSVDFILDDGIKSAIKKAQESVKQSTDKLRLDVMQHYDLHRDCIKGFKLSPDSVAQLGFQMAFYKLYAKFVATYESCSTSAFKHGRTETVRPLTMATKQCVEEFHKKSRPSNSDLKNLLKECTKVHNQLTKDAAMGQGFDRHLFALRYLAEEKGMKAPALYQDPVYAEANHFIISTSTLFGPAFSGGGFAPVVQDGLGIGYGFLDNFTGCLVSSYSPYRDGTAFVEALHSTYDDIYNVLSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ML83</accession>
    <name>A0AAV4ML83_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SRSF4</name>
        <name evidence="13" type="ORF">CEXT_487522</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the splicing factor SR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002329">
        <property type="protein sequence ID" value="GIX72560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ML83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12600">
        <property type="entry name" value="RRM2_SRSF4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000028">
        <property type="entry name" value="Putative serine/arginine-rich splicing factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047190">
        <property type="entry name" value="RRM2_SRSF4/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF53">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="34"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="158"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="117"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="232"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIX72560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="362" mass="42279" checksum="CE985F84D53C7876" modified="2024-11-27" version="1">MKAILAQVISYPEENKRKINKAYQNRMYGKYCTNMVLIFVIPQNYYLEILRTNFDCCDLNTFVIHFHNEGYGKIREILIKNGFGFVEFDDYRDADDAVYELNGRELLGERVTIEHARGSPRGNDMYRDRNRGYRAPLPSRRRQGGGRDKYGPPTRTEYRLIVENLSSRVSWQDLKDYMRQAGEVTYADAHKQRRNEGVVEFASFSDMKNALDKLDDTDLNGRRIKLVEDKSRRRRSRSRSRSKSSRSHSRSRSHSHSRSRSKSRSMSKSRSRSKSHSKSRSRSKSPSKARSNRSQSHKQSRSRSRSLSEDRHDRKSRSRSKSHKSRSRSNSRSRSRSKSSEKRMGSPIPKDDDVSNSAEEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MMD0</accession>
    <name>A0AAV4MMD0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_379831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002418">
        <property type="protein sequence ID" value="GIX73495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MMD0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX73495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="18202" checksum="F82959781E1B6650" modified="2024-11-27" version="1">MFQVLPSPFLIKPARCPTFFTRETVFLILRYVLHGHGPFGVLRRAACALKQRAQMKFMSLYTQWNEKKSCDIGLRSVDLKHGFPNKFQYSFFMIQPHSSLTPLHDDSSSFFHDSSSFIFHDSSSFILHDDSSFMIPPPSFFMMTPLRDSSSFFILLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVW0</accession>
    <name>A0AAV4MVW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_282081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020209">
        <property type="protein sequence ID" value="GIX75920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX75920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24865" checksum="482DB0319262AA11" modified="2024-11-27" version="1">MSPSISILNLVDAARKEQFARQQVRSRSNHARIKDRSISRRTTPFAFAPVCERVNDFGEQNLRMFIAEAPPPSFLPGLACLFTCRGRGRMGSFLSERRRCCLKWNQELSSSPNVTFARDLIRNLVDAARKEQFARQQVKSRSNHARLKDRSIRERTTPFTFVPVCERANDFGSRNLRMFIAKAPPLSFLGLRKRSVPFHSLRKERFFFQKGKDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWN1</accession>
    <name>A0AAV4MWN1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_70931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002694">
        <property type="protein sequence ID" value="GIX76783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWN1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="113" mass="13113" checksum="47C8786DAAD695B1" modified="2024-11-27" version="1">MIRTRWFCRNFAAIRLLTEEFIDSPTTDCHADRKRTIPLTPEENKDLARKAMAGGITLESPFMGKMHAERKKEEEKEKSLLEGLVLWLSIKEPEHNMTKSLETEECSELDDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0P8</accession>
    <name>A0AAV4N0P8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_48391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002834">
        <property type="protein sequence ID" value="GIX78340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0P8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX78340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="150" mass="17259" checksum="37541B997887052B" modified="2024-11-27" version="1">MFRNSGKGDGLVRCSFAARSHDEPFIRHADEEILTTLARAFNRRRFVLANLFGFLCIMQQQKLWTLEQWGMESDTWGQARTQDFALGPRRIRRRQDSKGDDDPEGGESEKTLFFDSFLCSLRGKEQTQDILSLSMDSHQGLKTLNTNPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0Q1</accession>
    <name>A0AAV4N0Q1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_48441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002834">
        <property type="protein sequence ID" value="GIX78347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0Q1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="17200" checksum="4B43B7C56F4CBA78" modified="2024-11-27" version="1">MRETDEKAAIFFCHRFRAFGFLRDLMAPEPLAQLFALERSIATAVRRGKHGASGAQGAALPGQLSHLRSMPNGPAEVEIFKLIDPFRFLTDWIVSPLLPRLADSHLRGMSSAFNYLRPLPLLSLPYHPLRSIPDCRQAVNTELLSGVGVEVVSIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0V2</accession>
    <name>A0AAV4N0V2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vitellogenin receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VgR_2</name>
        <name evidence="3" type="ORF">CEXT_452061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020410">
        <property type="protein sequence ID" value="GIX78427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0V2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000082">
        <property type="entry name" value="SEA_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50024">
        <property type="entry name" value="SEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="SEA" evidence="2">
        <location>
            <begin position="120"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX78427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="157" mass="17410" checksum="EE6E28CB97A7E444" modified="2024-11-27" version="1">MAKVLLSDQIGSPTPVWTVNPHLSRQDNGNSGVDNPAFYDSESGLCSREDAYPKKPVAWTGDETHCSKRQCGGRLVLLMVAVCLLLAVLMAMVTAVIYLAVGEVRTTWQDEAEFQDMEEGISLVEGHLRITNRVFTKDLLQSHSEAFRKLAFSDHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8N2</accession>
    <name>A0AAV4N8N2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Microtubule-actin cross-linking factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DST</name>
        <name evidence="8" type="ORF">CEXT_270871</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003063">
        <property type="protein sequence ID" value="GIX80798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8N2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030056">
        <property type="term" value="C:hemidesmosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005882">
        <property type="term" value="C:intermediate filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045104">
        <property type="term" value="P:intermediate filament cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042060">
        <property type="term" value="P:wound healing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000001">
        <property type="entry name" value="Microtubule-actin cross-linking factor 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.920.20:FF:000001">
        <property type="entry name" value="Microtubule-actin cross-linking factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000040">
        <property type="entry name" value="Short stop, isoform N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.20">
        <property type="entry name" value="Gas2-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003108">
        <property type="entry name" value="GAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036534">
        <property type="entry name" value="GAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043197">
        <property type="entry name" value="Plakin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23169">
        <property type="entry name" value="ENVOPLAKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23169:SF23">
        <property type="entry name" value="SHORT STOP, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02187">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00243">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143575">
        <property type="entry name" value="GAS2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51460">
        <property type="entry name" value="GAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="671"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="707"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="GAR" evidence="7">
        <location>
            <begin position="746"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="573"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="838"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="850"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="872"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="882"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="923"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="964"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1004"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX80798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1014" mass="117095" checksum="954C5575A1315245" modified="2024-11-27" version="1">MDLYNELDSNRYKVENIMQQGQNYLKKSSESNTKTLQHSLRTLKQRWDSVLNKANDRKIKLEIALREATEFHEALQQFVEWLTNAEKYLTGLKPVSRHMKAVLEQIEEHRNFQKDLGSHREVMLNLDKKGTHLKYFSQKQDVILIKNLLISVQHRWEKVVSKAAERTRALDHGYKESKEFHDAWTALSSWLDEAEKVLDNTTPIGNDPIKIKKLLSKHKEFQRSLVTKQITYDATMKSGRILKDKCPKQDVQLIQGMMDELKVRWNKVCSKSVDKQRKLEEALLYSGQFKDAVLALLDWFDKALNSLSDAKPYHGDLDTVTSLIEQHKSFEDELKNRGLSLESVCKTSNDLKKQASASDVENISFQVEELKTKWKTVSDLSEKKKTNLSQALQLAEKLYKLVHILLEWLSDAEMKLRFFGSLPEDEESTKKQISEHENFLSEMKDRENTKNDTLKLAQDILEKCHPDGISVIRHWITIIQSRWDEISAWTKQRDQRLRDHLLSLRDINDLLEDLLAWLTRAETSLTELEAQPLPDDLPTLDELIKEHQAFMTDMSKRQNDVEKISKAFSSKRHQNKGMLPAQVKEKSKEKLPRSGTPVSLKASTPLRPQIDSDIKHPRARLLLEKWRIVWLLAMERQRRLQDRRNYLLELDRIKNFDFNDWRNRYLGWLSNKKSRIMDQFKKIDKNNHGKVTKQEFIDGILKSKFVTSRLEMERVADIFDRNGDGFIDTKEYVETLRPEREDHPKTEAEKIQDEVQRQVSKCTCVHRFKVYQVGEGKYRFGDSQKLRLVRILRSTVMVRVGGGWVALDEFLVKNDPCRAKGRTNLELREQFILADGVSQSMTPFKPKPSPNSSVSSQSGTTNSMPSAGPITKIREKSERSTPMRQSRSSVENSSDISGPSFSETDSFSNRSCYSRTTPSSHLSPRIPSGKSSSRPSSRQGSRPASRAPSDLSQDGVEDYKNNRKTVTGNGVTQKMSSLPSHGKIKPLSESSKIPSAKKTPLNKETSRKMESRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N9R8</accession>
    <name>A0AAV4N9R8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_227241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020687">
        <property type="protein sequence ID" value="GIX81564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N9R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17341" checksum="EC34E14727D1629F" modified="2024-11-27" version="1">MTNSPFSNEKDQKHCPKRCHLVSIKRFVLHCFLVSYHPGIQIPHSQRFILADGNAIPSAQRNINNNKVPLVYVYIKGMAGETANRNGWARRAELSGGNDPRIKSGPETISRQPTREVSDRRERRSTLETTRGIFHEKRNRKALLSLVVGHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAF7</accession>
    <name>A0AAV4NAF7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_761751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020688">
        <property type="protein sequence ID" value="GIX81571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAF7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9413" checksum="EF605C5FA429B7F3" modified="2024-11-27" version="1">MLLSPEGSDPVSKRRKNYKKNCKKKEEYFVTSKQVNPFRPLSIAEGFAVFGFSSCRHSKIQFRKKFEYIQNGSPDDSFPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NB51</accession>
    <name>A0AAV4NB51_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_621841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003055">
        <property type="protein sequence ID" value="GIX80699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NB51"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="11791" checksum="DB45A21DF0FD41E4" modified="2024-11-27" version="1">MRNKNKNDPLPCTCWVSPPRVDPHVDEQLVPGVEWSQLPGAADPQAAEVLPLPLVHVELLYVADEAALALEHRLALHPTADVGTGTESFAVSALGPFRLSLVFCRLCNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLP7</accession>
    <name>A0AAV4NLP7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_655871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021009">
        <property type="protein sequence ID" value="GIX84876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLP7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10437" checksum="B5AAFB236904EEE4" modified="2024-11-27" version="1">MLEEKRPKPCRFGNVAQRLDYNTDDVFLHTAELLGNFQFTSPVDGNQQSGNKGSEHDFPKGANSHPISESPMITKKESRKDSPRPPRGGIRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQE4</accession>
    <name>A0AAV4NQE4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_599961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021192">
        <property type="protein sequence ID" value="GIX86986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQE4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX86986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20368" checksum="2094331C9A274201" modified="2024-11-27" version="1">MTVAMDNFIIQFNGLKISCREPRCYGIKVLVLIHWCWERLLLCQDSYTFGPYFKSSTTNGSCVLKICTVTCSETSTKFYLEGYSKIGWVARWVLASGNEIYFRLSDYRFDECWGSEKGRKYSFLFSLHLPRKFNRRMLSPLISIMFSILFQVSGRDMLVIIRNERPKKMKGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NQH0</accession>
    <name>A0AAV4NQH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_300442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003640">
        <property type="protein sequence ID" value="GIX87024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NQH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="234" mass="26730" checksum="F495DE42B729B80A" modified="2024-11-27" version="1">MCTRHGHYKSRQTLDKLEARLSQIGPSSEMAATTKDHLPFYTNTYKSNLKYVLKDNIAYPNSSEELQALLNAKDEIPNSSTEVAPNQITPTSEKIIMDTSEEPQNEPIPTEEPYQIPPKRLTCRDQTQDPKIQGPEIKNQYSPLVQMDTENSTAMPERKKQIPPFFITPNASWPETCKVLTSTVESLNISLSKGQFLKLTVNSERDYETLKLTLIKRNVLFKCYSLQNLNKNFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NRR7</accession>
    <name>A0AAV4NRR7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_704581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003680">
        <property type="protein sequence ID" value="GIX87466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NRR7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX87466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8852" checksum="3BFB6308703C519E" modified="2024-11-27" version="1">MHGCWTRDNKDIRFAVWKRFEYVFHSAKEGLAFVGRNEMNARNSSRTPIVQVAFENTTPEIIHTSNSKAGADYAMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NYH1</accession>
    <name>A0AAV4NYH1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Diacylglycerol kinase delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DGKD</name>
        <name evidence="6" type="ORF">CEXT_480181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003799">
        <property type="protein sequence ID" value="GIX88790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NYH1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF109">
        <property type="entry name" value="DIACYLGLYCEROL KINASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="4">
        <location>
            <begin position="29"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="DAGKc" evidence="5">
        <location>
            <begin position="145"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX88790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="266" mass="29985" checksum="7F67BF3ED569E20C" modified="2024-11-27" version="1">MEDWITAFKNVSNKDFYEGTDNQEFLSGQHNWCITNHARPTFCNVCRDALPGVRSTGLSCEVCKFKAHKRCAIKAPNNYWKCLWCRALVHHATCKAQYPLKCPLGVCRASIVPPTSLHSISNDESWEAICPLGCSPLLVFVNSKLQMFRTFNPLRVLVCGGDGSVSWVLTEIDKLSMNKQCQVGVLPLGTGNDLARVLGWGSSCNDDAQLPQMLENYEKATVKSLDRWCIMTYEKSVLAPRKTQTKRLKIYLLPLVMVMMILLIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P570</accession>
    <name>A0AAV4P570_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_209241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021559">
        <property type="protein sequence ID" value="GIX91115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P570"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11869" checksum="1AB90363A719E083" modified="2024-11-27" version="1">MQNLLIDINQYFHERISDHWYDCISLSKWRQPLYCSQIVMRSNSFPSPCGNSFAPSPMDYGYEKRVHNPYDLSAIVNAGMCTAIFDSDRIALFFSSSCSILLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P6W9</accession>
    <name>A0AAV4P6W9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_387461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003974">
        <property type="protein sequence ID" value="GIX90897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P6W9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="12099" checksum="3715EDE08D681D08" modified="2024-11-27" version="1">MFYPSKDGLGRLDCQVPFCWCMKRNRFGSPPEKKKKNYNKRKRKQETEIKRAFKLLYAPAFQIIKLKGWVCGEMRDVGFYHKSLKFAGVLLDQVARDKTEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9T9</accession>
    <name>A0AAV4P9T9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_770161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004317">
        <property type="protein sequence ID" value="GIX93970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9T9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX93970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="69" mass="8012" checksum="A94E58A24AB66CCD" modified="2024-11-27" version="1">MRVIVEPLMEPIVCVTNSRSFMVLYKSGITPEAHLILGLRELKRRGNRSRRIESRKKEATKAMDSRILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PH02</accession>
    <name>A0AAV4PH02_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_147791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004478">
        <property type="protein sequence ID" value="GIX95204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PH02"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="179" mass="19954" checksum="F37A8177DB7347D0" modified="2024-11-27" version="1">MECVNLLDQGRPVSQIQLATARLAVSFLSNMECVNLLGQGMPDSQIHLAKTRVTVCFLSNMKLVNLLDQGRLAKYNWLQHGWLSPSYQICNESTFLVRIGLFGEYHWLQPGWGTPAYQIWNASTFMARVGRPGSQIKLAIPREAVSFLSNMECVSLLGQGVGLLAKYHWLQPGCLSPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSA9</accession>
    <name>A0AAV4PSA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_271491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005065">
        <property type="protein sequence ID" value="GIX99574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX99574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8816" checksum="BFA6DFA138C1ED0C" modified="2024-11-27" version="1">MECFQPNLISQHDNLSNSQRETELGAIQVADCFQFNGFQQNGRRLRCSESSKEAEVKANALIMTYSDEPLKAGLFIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PTW1</accession>
    <name>A0AAV4PTW1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_718801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005067">
        <property type="protein sequence ID" value="GIX99591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PTW1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12330" checksum="6ABB7B17CE48E78B" modified="2024-11-27" version="1">MFPFLVFPFPLSERTHLIFVLEFLFHEAQSPEFPGELESREDGVLAGEGDEGWRSQCPVRVDTGSRMSKTVLAAGLDTLRATAPNLVRSRDADVQRRRPLSQWTTGPRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWZ1</accession>
    <name>A0AAV4PWZ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_799811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005346">
        <property type="protein sequence ID" value="GIY01612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWZ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY01612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="134" mass="14846" checksum="CC1FE86BE39EB6EC" modified="2024-11-27" version="1">MEEADKQHGINNASVIFVRQEEDIALNDTKCSGIPASFPKLLNFSKKRTTYLFSLHLPAPNKSSEANSPPRITLYYVEACGFEAGMDSEALTTFGTFIWFIISVDGAEVPAQCERSNKALTTLLTFVRFLASMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXT1</accession>
    <name>A0AAV4PXT1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNase H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_208080_1</name>
        <name evidence="2" type="ORF">CEXT_20181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005249">
        <property type="protein sequence ID" value="GIY01034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXT1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY01034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="264" mass="29506" checksum="4100396BA45550B8" modified="2024-11-27" version="1">MKFSFPEEDERDLATPVVPVIDPADDVKSSGVEEKTKPDSSSSPSSLSDKEEDDDEEEEDEEEEEEENEDSQNNKDQPFQNVQRSATVIHVKEPEKDEEESSEEESSEEESSEEESDKLKRCPTQVIRPPGQVAASEKKKEESESEEESSEEESSSDETDDKKIDNEQKVSTPSKKQEENKTTPTSGESYWPKLQKKDSLPTQDNLTLFIGQCKDIDEMLGVPSPVSPGSAKIANSSSSSKQQPFSFQSNDVAKQKGIKNFDIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q146</accession>
    <name>A0AAV4Q146_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GAE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AP1G1</name>
        <name evidence="9" type="ORF">CEXT_485491</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005545">
        <property type="protein sequence ID" value="GIY03150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q146"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008153">
        <property type="entry name" value="GAE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50180">
        <property type="entry name" value="GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GAE" evidence="8">
        <location>
            <begin position="194"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY03150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="314" mass="35442" checksum="5A9791B11FEE693D" modified="2024-11-27" version="1">MVTPDEILDLFEKVTVNIHMTLTTKEYAVTALMKLSVRYPDLAPQIKRFLDIFGTNVNVELQQRAIEFSSLFRKFDNLRPSLLERMPAMENKSSRETVVQNGEVGDDELNVVKDEKENKNIEDSSVLLDLLSSTSETNNPSEVPHIEEKSGSKEPDLLDLLGGLELEPQSESSLPPLNQNIILERYLTSQTESEGIPSITAFEKNGLRIIFEFEKPPDNPEMIIINLVATNLSFSPINDFLLQAAVPKVFQLQLLPPTNNYIPANNLGKIQQTLKILNPSKSQLRMKLRISYISNGQNFLEQAEVNNIPQAVYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q973</accession>
    <name>A0AAV4Q973_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_400341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005763">
        <property type="protein sequence ID" value="GIY04869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q973"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY04869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="9138" checksum="CD0F688320F04487" modified="2024-11-27" version="1">MSSTKRRWVFFFPCSLSNLTLSTETRKWFHIPRVGSSPSHEARLRWEVSSGANAGKWVMHDRQMQFFEDILRHPDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QG54</accession>
    <name>A0AAV4QG54_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Homeodomain-interacting protein kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HIPK2</name>
        <name evidence="2" type="ORF">CEXT_539751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005948">
        <property type="protein sequence ID" value="GIY06333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QG54"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY06333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="491" mass="53516" checksum="D021B08725C92B08" modified="2024-11-27" version="1">MMEVCRKNKTSFDNNGNQVSIVSNFSPTSNVTLAFNNQLNNLQNQYQLQSTSFYQPSQVAAPTRVNISQTQGQPRVAAVATNQYAAAAAAAAAAARVDTFQHAAQSLCVSSILCPSYPGLNSPAKHVVPVVAQAAQPQTLHIQPSLLTQVGAQQYVPVSVVEQNGRQMLLTNAVQSGWPTILERAALLSDQPTVIPVELHDTVMYEHLRDRNNHLNNLLPQAALTATNVQPSWNVIAPNSNPSQCTVYKAREPHSSNVSKVSSSSSSGSTSIKRQTKLRPGKEKDINNCQLSPVKKRVKESTPPKWENNSNLQNSHHLQPNQNCCPSINQPKLIVSGSDKEQQRPTIIIHDTPSPVVSVITISSDSDEDIESSICCDKKKCKACDSNKLAKIKSLILCTSEVSSTTNCDSVLSLTPEEENAMYCMQRSTSKSNLSRSHHGTSQQNRKNVISCVTIPDSDSEGYYSPLQALPHFTASVIGKVIKPEPQKRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QI50</accession>
    <name>A0AAV4QI50_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_139761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006145">
        <property type="protein sequence ID" value="GIY07730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QI50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY07730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9985" checksum="9A27744CC8374AFA" modified="2024-11-27" version="1">MSTSKCYGVPGTITSIAVVSVDTVVVTGSYSGIFNDQHRSRSDVILFRRIPILHTASHDSAYSVFVCGDTEENYHCQLAFVIIIHDQYLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QL27</accession>
    <name>A0AAV4QL27_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_699231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006456">
        <property type="protein sequence ID" value="GIY10024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QL27"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11402" checksum="00F8E6CA1B9404EB" modified="2024-11-27" version="1">MFTREPYLVACETGRIPHPGCFRESPPNRYSHPSTPLALQQVSVRSSGPAEEVPEEVESPSPGGKKVYFLPSGEAFSHSQRTIDPLQLNDHQPFLTPLLSLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2E1</accession>
    <name>A0AAV4R2E1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CREB-regulated transcription coactivator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Crtc1</name>
        <name evidence="13" type="ORF">CEXT_725041</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TORC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007089">
        <property type="protein sequence ID" value="GIY14471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2E1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008140">
        <property type="term" value="F:cAMP response element binding protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051289">
        <property type="term" value="P:protein homotetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024786">
        <property type="entry name" value="TORC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024784">
        <property type="entry name" value="TORC_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024783">
        <property type="entry name" value="TORC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13589">
        <property type="entry name" value="CREB-REGULATED TRANSCRIPTION COACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13589:SF15">
        <property type="entry name" value="CREB-REGULATED TRANSCRIPTION COACTIVATOR, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12885">
        <property type="entry name" value="TORC_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12884">
        <property type="entry name" value="TORC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transducer of regulated CREB activity N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Transducer of regulated CREB activity middle" evidence="12">
        <location>
            <begin position="121"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="82"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="261"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY14471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="341" mass="36919" checksum="B3E1437113ACD265" modified="2024-11-27" version="1">MANPRKFSEKIALHNQKQAEETAAFEQIMKEVIGATRGPKHHHLHINQSLGAYRAGSLPNVNQIGNNSIDLQSALNSLEDMKQGRDVSADRMHRERGRHSIDVSPYNSSYLSPPPDTNWRRTNSDSALHQSAMNQQDSYHGANTPPDNRNMVDGNAMHENDQQQFVSLQQSRPKSCEVPGINIYPSQDESGSIHVPISSNTGSLPDLTNLHIPPPLMTPLDVEDQTGLVNSGVQMHHSPPNTTTLSPSSLQHQTRILGSSLSGGTLITTSSGGGSRHSSPGPSPSPPSRRRHHHNLTNLVIGSGSPPSWLPAHCSAASSTRTNLKAIIIIIITTIIITILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R7D4</accession>
    <name>A0AAV4R7D4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_1496_1</name>
        <name evidence="1" type="ORF">CEXT_481341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007443">
        <property type="protein sequence ID" value="GIY16949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R7D4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY16949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="21108" checksum="5B8BA1E4C48095E7" modified="2024-11-27" version="1">MKSCQPKANSFLWVRFLAEDCLEFSCESFRILITVLETSNCFTRVVLSTENRNSTIVLQTDVGYTMRDIRYWWLEGPRSVGMSSDVELPQFKVIGHRQRSKEVPLTTANILLTDKTCLSSNPNITVFIRRITSNCRSSNTTKCVLCVPREFSVHIACQGNRTYPGARLQKDLKNQTNLPKEEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RCB8</accession>
    <name>A0AAV4RCB8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_440661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007778">
        <property type="protein sequence ID" value="GIY19618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RCB8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY19618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8416" checksum="766142A69582AF5D" modified="2024-11-27" version="1">MRRKSKRERERRVGGPVNTLSDRGGASRILPPPPMKADNGEQGKRACLHNPVQTTPGKGAETEAAGIKIGVKGLMKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJ32</accession>
    <name>A0AAV4RJ32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ester hydrolase C11orf54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CK054_0</name>
        <name evidence="8" type="ORF">CEXT_542172</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008001">
        <property type="protein sequence ID" value="GIY21322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJ32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015021">
        <property type="entry name" value="C11orf54_DUF1907"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13204:SF1">
        <property type="entry name" value="ESTER HYDROLASE C11ORF54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13204">
        <property type="entry name" value="PTD012 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08925">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01168">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117856">
        <property type="entry name" value="AF0104/ALDC/Ptd012-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DUF1907" evidence="7">
        <location>
            <begin position="112"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY21322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="264" mass="29786" checksum="CA5DF491DB397338" modified="2024-11-27" version="1">MQVTDVIESVKNWRALRGERTISSESVVDFYSYFREVVEVFASHHSKQLAGPNETFVTRRKYNRGRITTTMTQTVFGIFCKIRRLIIFFYKSCQKLKNINYFNLNWKKLPQFLKDGLSETFSYAEVDIVDCPDLQEKPYMLSAPGLCGSPCIADVGGVEYLIPLAQKDKVYDFKNIAKSIGMANASIIGAGAGPRPHIGINCEMMANLKLGEDENINTHIAKLNKDGDCELVCLKDNTQFCLLGNLFISEGKPGRVNKYILLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RNW4</accession>
    <name>A0AAV4RNW4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposon Ty3-I Gag-Pol polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TY3B-I_1355</name>
        <name evidence="2" type="ORF">CEXT_532011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008272">
        <property type="protein sequence ID" value="GIY23430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RNW4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057670">
        <property type="entry name" value="SH3_retrovirus"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25597">
        <property type="entry name" value="SH3_retrovirus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retroviral polymerase SH3-like" evidence="1">
        <location>
            <begin position="59"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21696" checksum="1920C68C3DF1B4DE" modified="2024-11-27" version="1">MAELYCDIFQFPKLLDFNYSFWKADNKVILMNRECWEFICGTAVPYQDSASVKSKSSSLVFGYVYKVNRNKLQSPAKLRVLVGYALRTKGYRSFIPQESKVIENIHMKIDETKNGNIPDVNAQTIKDKYPIPCILDFTSELHGCEIFSHVNLVKALHQIPIALEDIHKTALHTIRTLRKRMRMPLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVM1</accession>
    <name>A0AAV4RVM1_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LAGLIDADG homing endonuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_456141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008409">
        <property type="protein sequence ID" value="GIY24431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVM1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY24431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14499" checksum="B6F441EAE62F5490" modified="2024-11-27" version="1">MGYGREFLLDDDDDEESLLRLIGWIDEIGRSAFAARGDASPNCRVSEIVLRFALERSESSNVNQSRCLDKILKRIDRRSVTFLYTKERGRQTRVIDELVKRDLTRLTRGHAKLIASFAQSPAEGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S995</accession>
    <name>A0AAV4S995_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_197051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009033">
        <property type="protein sequence ID" value="GIY29186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S995"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9140" checksum="9F105DE06D272CF8" modified="2024-11-27" version="1">MFLFTSLLIPGSSTLSYYRPPLPGTPGSLSEFDSIMPTTVDNLLVRNECQMVRVIAFPCDPPIPPAGMAISRGGCPDPFHGRDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SA69</accession>
    <name>A0AAV4SA69_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_549971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009198">
        <property type="protein sequence ID" value="GIY30239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SA69"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022008">
        <property type="term" value="P:neurogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774:SF4">
        <property type="entry name" value="AXUNDEAD, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="24"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY30239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="420" mass="47733" checksum="D9A2069C8B0887C7" modified="2024-11-27" version="1">MSQLLLSASHAGAGEHLFLSEELSDVTILIQINAQGEWRFPAHRLVLASQSSVFHRMLESEFSEKATGSILIKDIKPKIIELLLGYIYRGRVVLQNWRDGLELLQAAHKYQVEPLVQFCCKFLETVISISNVCYIYNEACIYSLLSVKEKCLKLILDAGFILLRSKAFEILEKDSVMDIITNSNLNIDSELMVFEALLKWSPMQCCRIGLQVNEANILKELTPFLRYVCFDDMSDTEKSALPPAVLSCVKPNNRNRIAHCVPDSLSLYSHCFVFHTEQEVMECVGESLNCINFSLDTTQYMIGLKFMVITPECQPHMNLTMVKVQGGSSTNCYTMNLNSAAWKEGLQMNERKRCEAHILLRQPCRLDPKTVYKLNLIDRLQNTFCPKTKLFTKTLLTEKGHVNLSLHSESVWGVTGLIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SI31</accession>
    <name>A0AAV4SI31_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_712731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009721">
        <property type="protein sequence ID" value="GIY34078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SI31"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY34078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11382" checksum="B0B1783A1D1B35BA" modified="2024-11-27" version="1">MCNASKIVDLIFSTACKIDEDDSLRRNVLLKLTLESLKSKQRRMRKRRHKLKLKNKKAFRQTKIDQSQLPKDGDSLGLDNFSSDIKSIAVSDKSEEKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SKY4</accession>
    <name>A0AAV4SKY4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_534791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009497">
        <property type="protein sequence ID" value="GIY32373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SKY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9415" checksum="502ED0F88DD64824" modified="2024-11-27" version="1">MVLQDRYYGMKMDDVLSLDMDPNEKSISVKMHMHEMERCSWEMLPATVCKPYCFHLAVFVFVAVPFQVHSLFLVVINEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SRW6</accession>
    <name>A0AAV4SRW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">mRNA decay activator protein ZFP36L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Zfp36l1_1</name>
        <name evidence="8" type="ORF">CEXT_598161</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009955">
        <property type="protein sequence ID" value="GIY35739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SRW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000001">
        <property type="entry name" value="zinc finger CCCH domain-containing protein 15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000002">
        <property type="entry name" value="Zinc finger protein 36, C3H1 type-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="176"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY35739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="312" mass="34848" checksum="A970544CFD329FE9" modified="2024-11-27" version="1">MTLMCIERAQSPTHKGNFLQGGKSAVSNINQQNANNNHRRNNSCSPPLSKSACTQQQQHDIPANKSNANSESRKLERSCSSSDADRRGAVQSNSSRYKTELCRPFEENGSCKYGDKCQFAHGKKELRNMIRHPKYKTELCRTFHTTGLCPYGPRCHFIHNSEQNKKSLLTTLTTAPNAGLRQDEGPRSSLGSDGEVSPPSSHGGSPTETKSFDDIFQQQPTPMSPCYNNQGFFNQDLLNIQRYIDFGSTFDYKNDFYDSVNGFNDKYGSNNNNYQNGTVLDLHPVGPLTPTSPLETNGVFLRLPIFDAFQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SXH2</accession>
    <name>A0AAV4SXH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_593251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010412">
        <property type="protein sequence ID" value="GIY39143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SXH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8369" checksum="0461E56E6CC94A74" modified="2024-11-27" version="1">MAYWTDLPCVLEASCNVSESSTHTRYRHGNRRSKELVAMDTGKDLSFCWCSFESLACFEVTRAPSVIYEALGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2W4</accession>
    <name>A0AAV4T2W4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_704381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010485">
        <property type="protein sequence ID" value="GIY39581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2W4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10054" checksum="762950343FFDD361" modified="2024-11-27" version="1">MHGIPYFSNASGVHCNNLRCKKRLPGHWSLSGPNHTYFSGFKKPPWLENQQDRKESEKLSENSTHEYTNSTGTNANLQDSPFGVVDFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5E3</accession>
    <name>A0AAV4T5E3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_474071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010774">
        <property type="protein sequence ID" value="GIY41903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13161" checksum="2DE52F5F331AA98E" modified="2024-11-27" version="1">MVAIIALGTPNSHYSCQARRVQLVRIENVCNHASLTTGKECPQPRCGRSSASRHTERYLFTYEKALGCWKAGLQLKLRWHLVLGVSSRKRKYSLHLSDAASPVLTPVPEPGARQQPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TFL8</accession>
    <name>A0AAV4TFL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Unconventional myosin-Ib</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MYO1B</name>
        <name evidence="2" type="ORF">CEXT_83251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011102">
        <property type="protein sequence ID" value="GIY44186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TFL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010926">
        <property type="entry name" value="Myosin_TH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34969">
        <property type="entry name" value="OS01G0621700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34969:SF1">
        <property type="entry name" value="TH1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06017">
        <property type="entry name" value="Myosin_TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51757">
        <property type="entry name" value="TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TH1" evidence="1">
        <location>
            <begin position="118"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY44186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="307" mass="35352" checksum="4355433B2C999B9F" modified="2024-11-27" version="1">MCEDLRYEFDLRRCVKLFTPANKISISRMCEDQHSFDEVIESARGKGTCCGCPGTYLLNLLCVETGRRPLDAYRKPVTTLGKLYHKWRCHKYRLRFDQIARNRMREKVTASMLFRDRKSSYHKSVSHPFRGDYVRLRHNVKWKKTAAETGDQYVVFADIINKIARASGKCLQTLFVVSTSAMLVMDQRTLQIKYRIPATDIFRISLSPFVDDLAVFHVRAAFCCSQATRKKGDFLFETGHVIEIVTKLYLVIQNATESLEVNIATEFEANFGKESVVLAFKCTGLLRKSSRDRSRSTGEEIAWEVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TXH0</accession>
    <name>A0AAV4TXH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">All trans-polyprenyl-diphosphate synthase PDSS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Pdss2</name>
        <name evidence="2" type="ORF">CEXT_470681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011950">
        <property type="protein sequence ID" value="GIY50171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TXH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042811">
        <property type="term" value="P:pheromone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF55">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY50171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="389" mass="43203" checksum="030D711B9274E5F2" modified="2024-11-27" version="1">MECEACCKSYGLMTLSSHVSTTTSSSNWSVSVKTHDWNRAVSDAEKLVGHPTTFFSLKCLLSEEFTSVAMNLRRLVGTDHPILKTAKRLVYHGRTNMQTRGLVVLLLSKAAGHTPTCKDLNSINESGVTARQQTLAEITEMIHTAHLIHKGILNLSPTVVPEENTREDLQLGNKVSILSGDYLLANACKGLANLRNCKVVDLISKAIADFMQAEFLGEHDKQGNALPVREMSLSTWEEKNILCAGSLLANSCKSTLELAGFDEQLQAKAFEFGKNVGLAWQVKFYSDLQPFVDHLNYPAGNKFDLTSIPVIFHLEKNQMKVDSLRQEIDNDVSNFDFKSLHESIMADDNVRRSKNLLQHYSQQAEDLLPLFGSSAASKALFNIINSIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UCW8</accession>
    <name>A0AAV4UCW8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_4226_1</name>
        <name evidence="2" type="ORF">CEXT_505331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012652">
        <property type="protein sequence ID" value="GIY55567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UCW8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY55567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12085" checksum="6370B78E6DC1B488" modified="2024-11-27" version="1">MQSSSLETYLYLQLRGKTCDNSQWRDDQNRVVLYSNGINGFLYPKMVLCLSPSTEPSNLKSEIFDFFPRLGITITHLPTVIFIEILSCTTILTLTRIRQFQTKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJ71</accession>
    <name>A0AAV4UJ71_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_487811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012938">
        <property type="protein sequence ID" value="GIY57649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJ71"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043955014" evidence="2">
        <location>
            <begin position="16"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY57649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="162" mass="18091" checksum="AAFF91313BEC2C88" modified="2024-11-27" version="1">MFILAVLSCIVVAQASLLPVLQPHHAPSYEIRHAVRDHLGERVREEVGNPAVGVVAGSSRIADFRGVGRQVNHVADPSGLRAHIRTNEVAAAPQYVSPYLANPYYRSFGHDGLVYQNMDLIEQIWTWIWLQWPFFNRYGYGNALGYSSLLGNAFNYGVPLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UNB5</accession>
    <name>A0AAV4UNB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_405771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013198">
        <property type="protein sequence ID" value="GIY59350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UNB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY59350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="338" mass="36960" checksum="E44ABD4447449DCB" modified="2024-11-27" version="1">MLKQSAKSPSAAVLHSEDSVARGAPRGGRLRSPSGLSTLKPIKSFWTAPGGQVRPPLLTPFTVWSVCWSSPGDWYKRKRVSCVEGGSGSTQWVASTHNLEVEAEKGWSSPSASLEGLEAGVAGPHSRDAWGVPGQPQAASPTEVRVAEQRAPSTSRKCFGARTLVGPWVRWCEGVDQRCHCFVSQSGRLNYYRSRQSELSSPLVVISDLFLPRRVKRRTSLYLARTSAVLQSWWADLQTSGRTYLLRHGNSGPKNRSYFGGHGCPPPLAPRVVWTYKQEGLPLLLKADLPPMEFPPTPWAPRPAASPSAPPPGRPPTPSAQDLKVKSRRNKPLVSQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4URH0</accession>
    <name>A0AAV4URH0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Breast cancer anti-estrogen resistance protein 3 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">bcar3</name>
        <name evidence="8" type="ORF">CEXT_89231</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013310">
        <property type="protein sequence ID" value="GIY60323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4URH0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001784">
        <property type="term" value="F:phosphotyrosine residue binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10337">
        <property type="entry name" value="SH2_BCAR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000013">
        <property type="entry name" value="SH2 domain-containing protein 3C isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.840.10:FF:000015">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051853">
        <property type="entry name" value="SH2-Ras-GEF_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044102">
        <property type="entry name" value="SH2_SHEP1/BCAR3/NSP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14247">
        <property type="entry name" value="BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14247:SF8">
        <property type="entry name" value="RAS-GEF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0727">SH2 domain</keyword>
    <feature type="domain" description="SAM" evidence="7">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="5">
        <location>
            <begin position="169"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="6">
        <location>
            <begin position="531"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="72"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="332"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY60323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="813" mass="92262" checksum="997ED1514BD5F5DC" modified="2024-11-27" version="1">MASQQPHLSIDLWLEKLDMNVYKPVFEDYNGVEDILWMTERDLKNLGIKNGSHRARLATSLTILKDKYLKTSREGRNTLSPNDRSPHSERSRSNISMSPIHQIHFEENQTGVRSWPSTRPSTNHATKHSSPRSSTVKNFVGTDATAEDLKRALEKELSLDSSDLRSYAWYHGTILRQRAEELVSNDGNFLVRDCISQPGDFVITCKWNDVPLHFIIKKVILNPDTVYERFQYCFEKESFDSIPDFITYYVGSKCPLSEASGVIISCPVNRIMPLSYYASRYGIQCQIHYVAKALEKIPSSPDHQNNNTVPLAPVMEINQVDTLNSRWPQQSFENKRGVSNNKTTETNNKIKPPPHQNSNLIKMGSDPMLSPNTERRSFERRPNSGLFNTETLTPVSVAIEDKPPPKPSRVPSKKCAHRPLVVKKERKLSEVDDNDIGSPNFIPVPGISLAHSHFERQISETRFSFLDRPSVSSCSSTPDAESVIQYFTMPKICDRSVFKPQQFQTPLLATENPPLEGSVLSKLRQIFLCATPKTIASHLTRMDLELAKHFGNVDLGLGVNSGLELFLLPQGEQMQKDLLERTKCIKLFVAVLILTCPDEEERMKILNRWIEVAIETKTSLGNFYGFTSIMLGLTLPEILGLHSVWLALRRFHTETAFMFETRLRPTFKSLQNGSGLEAPNTCLPYILSLILILQQHISVMNAMEKSVDNVSNDISNFILPGNSSTSDFGLQLLADHLETGRNILQQIPVFKKNGEMSLQSLKYQDILLDVFNTEFHLRMLWGYRGCDVCSEQRHTIFQKVVHSLYNKCTAVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4USS4</accession>
    <name>A0AAV4USS4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_1201</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013402">
        <property type="protein sequence ID" value="GIY60951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4USS4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY60951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9727" checksum="8EACE91BFBC42024" modified="2024-11-27" version="1">MDYAVDLDLPEQPNQRRSSASSHFIGRSAPIESCVLPLPKVFNPVLPVVMWVPTPTCGIIAYFKEQIVRRFSVINIHHRRVDSVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UTU7</accession>
    <name>A0AAV4UTU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_285861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013380">
        <property type="protein sequence ID" value="GIY60810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UTU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY60810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="63" mass="7393" checksum="3D16202AD2E871E3" modified="2024-11-27" version="1" fragment="single">LLQKELPDKRTSLYANRSLFFNKIMNRFHELHCKNRSRFPSPRDYVTPGSGKVQGFGPRFPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V0T2</accession>
    <name>A0AAV4V0T2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_151031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013707">
        <property type="protein sequence ID" value="GIY63165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V0T2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9905" checksum="454C56105AB6C449" modified="2024-11-27" version="1">MRYGRLKELCNPISCAVRDIWSLKVALVNGCLIRVTPTSRVMEKGGKVKYKYGWIGCYSVCPIDQSLKGVRFLTALTGYVTANINGFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V8Z2</accession>
    <name>A0AAV4V8Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_496881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014147">
        <property type="protein sequence ID" value="GIY66715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V8Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8186" checksum="B50BEEB44BF71EA6" modified="2024-11-27" version="1">MGRQKLLEAEPFWENVSFPEVLTKLCLTWGTNDPSSSLPKNDLNLFVYVPCSLGHLNGFRLRFESIYQKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VA47</accession>
    <name>A0AAV4VA47_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_683201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="4">AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014109">
        <property type="protein sequence ID" value="GIY66360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VA47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="114"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="196"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="265"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="363"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY66360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="386" mass="43702" checksum="F5F01352378065ED" modified="2024-11-27" version="1">MSFRQEMLSSFHLRRTEHVDYTKMPEEEVIPSFLRRLSCDDVMPTSGKIVVLSVDLLVKNAFNALVTNDIRSAPLLLQHLLYYLNYLMKFVGMLIYRFLNLLYYYNFELITGIENKPIIRIKGSESLTQAAKILIQQGVHRLPVQDDSGNAVVFVMTKRRLLQYLQEKLFSKFVESKNVNMPSFFTKTIQELQVGTFEDIAVINEDTKVIDALNLFVSRKVSALPVLDDKGSVIDVFQKFDVFALAKNQTYHDLDIPVKSLDKSYSRDTTGTCTFDETLETVITKFVSNKFHRLVVVDKNYAPAGMISLSDVLKFLVVQPLVKMENASVSRTIPEDSEGAVGGTETEEAEVDVDLSTGVAHMKIGDGNKPDSFDETPPRRLLTTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCX6</accession>
    <name>A0AAV4VCX6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Slc25a51</name>
        <name evidence="12" type="ORF">CEXT_140671</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014308">
        <property type="protein sequence ID" value="GIY67991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCX6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051724">
        <property type="term" value="F:NAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052465">
        <property type="entry name" value="Mito_NAD+_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46131">
        <property type="entry name" value="SD08549P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46131:SF1">
        <property type="entry name" value="SD08549P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="43"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="132"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="228"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY67991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="323" mass="37030" checksum="9FF45240F4700EC9" modified="2024-11-27" version="1">MLNNIIQEFIDKVMCCINKMAIAPIDNKEYPISNKEPVMPLSDSRLTEYVCGWGSGFINIMITFPINKVMFRQMLHGVDSQHAFNQIKREGMHFLYRGVLPPLLQKATSTSIMFGSYKEFSEIIQGKFPSMQKFSVLCTAAILAGSAEAVLTPFERIQTLLQDRHYNTKFKNTYHAFSELRKQHGFKEFYRGMTPILLRNSVGNILFFGLKDFVKDFLPIKSTDSVLQEFVKDFISGAFVGAFTSTVFYPVNVVKTKMQVNCGTPFVSLSEAFKQTYIERDRSIRKLYYGVHVNYTRSFLSWGIINASNQLLKKIFFNDTSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VEF8</accession>
    <name>A0AAV4VEF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_74401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014373">
        <property type="protein sequence ID" value="GIY68394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VEF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY68394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="8810" checksum="7470629D40E0C9DD" modified="2024-11-27" version="1">MPEQNSSFTCHLCQHDTKTEHIDTPSSMHICHQRNTVEEAYQYGSFLVNLVGHVVVHPEGFSSLQKQQMGANTDTTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VJS7</accession>
    <name>A0AAV4VJS7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_620451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014576">
        <property type="protein sequence ID" value="GIY69705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VJS7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY69705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="237" mass="26993" checksum="85917C6F7B8904A1" modified="2024-11-27" version="1">MEQTRDYCMVDSILFEHIVKVGFPARLCGTPGEDRPFWLTENGLLCRDRRNQLQESLPLSGCPRISCLGKKEDGSLEEECLLRMGFWTQYFSEHIVKVGFPARLCGTPGEDRPFWLTENGLLCRDRRNQLQESLPLSGCPPNQLPGEKKRRWFIRGGMPFENGLLVQKVGDSILFEHITLKVGFPARLCGTPGEDRPFWLTENGLLCRDRRNQLQESLPLSGCPRISCLGEKKGMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VW40</accession>
    <name>A0AAV4VW40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_267501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015244">
        <property type="protein sequence ID" value="GIY74661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VW40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY74661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="38" mass="3919" checksum="584A055EEA54B75D" modified="2024-11-27" version="1" fragment="single">MPEVPGNKAPAPVSNPAPTTAKKNAARQPRVLPSPVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VY64</accession>
    <name>A0AAV4VY64_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_790781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015314">
        <property type="protein sequence ID" value="GIY75237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VY64"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10753" checksum="5DDCF33DB934B365" modified="2024-11-27" version="1">MSKLTPCSSLSRNSPLPPTRHRNNSFSFGNRVAKRGKIRRDDVFASQQLVAFTKMVSKWFRMNDVEKDSPCEETRRWQSECSPTAETNRGIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W0P4</accession>
    <name>A0AAV4W0P4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_257674_1</name>
        <name evidence="2" type="ORF">CEXT_26901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015346">
        <property type="protein sequence ID" value="GIY75479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W0P4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY75479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15356" checksum="E6314C82DB2F26DD" modified="2024-11-27" version="1">MDITMNKCKHCLTNINSDILLLSETWTISRDTFELNGFDHHHLDLSLRRPRGVSIYIKHHLKLLVESVEMSSNQDLGIHVLVANFKTEVCVAVLYAKPGSSDDDIIDAIDESLDSKNRDNKTILAGDFNIDMGTESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9Y8</accession>
    <name>A0AAV4W9Y8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sarcoplasmic calcium-binding proteins I, III, and IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">X975_22010</name>
        <name evidence="1" type="ORF">CEXT_592971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015777">
        <property type="protein sequence ID" value="GIY78634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9Y8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11728" checksum="D9D03BF40E8A0E94" modified="2024-11-27" version="1">MLSCALKRVCFVFAEDGLFCVKDYKKYLTAHNMDVTRAKECFDSMLNDEDRGNGNAMTSDRFRELVYDFWVSQNPDSPGKYVCGTFDSALLQELEGMNKTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WL50</accession>
    <name>A0AAV4WL50_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">CEXT_352151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016251">
        <property type="protein sequence ID" value="GIY82489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WL50"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY82489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="244" mass="26975" checksum="D39D51BEFE6C6148" modified="2024-11-27" version="1">MPTEHNHDSDGAEVTLFPSASEVSELLSPHCTRPKFNFIKLVCHQCSRRFFSAGGLERHLFAVHGINLNSHDDLPPTSAHSSHVVDPPEELLRHGMSTGPPSCAPFTKIGPAKSWAAIVAKPAISTTQPWAGLPLTPHTSFSSTPRSPGQTRPTQADGSAAKGGSPHNALPPVQRVRKKITFKNDSEDLDAVSHVVLFPQRQIKKRRRNFPCLHCDFTFRTMKSRDDHNVVHVLEEQLRIINTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRE5</accession>
    <name>A0AAV4WRE5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_276121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016657">
        <property type="protein sequence ID" value="GIY85417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRE5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY85417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9833" checksum="7B5D1FF497CE9A37" modified="2024-11-27" version="1">MTFANPQVTKPGSIFTTQDNSSNNGKRRKKGKQNGLFSRASMIFASSASVLCVCVGGWGEDSYWISDIRFSDPKSHYRCGWLEDLFCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRY4</accession>
    <name>A0AAV4WRY4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_199031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016659">
        <property type="protein sequence ID" value="GIY85452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRY4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043618680" description="Ribosomal protein S18" evidence="2">
        <location>
            <begin position="17"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY85452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16641" checksum="196D93E52FB6C077" modified="2024-11-27" version="1">MHFNHLIFLFCNRALLQLFNNNCCYFFRPIFFTWVRSLQTTLFASRNSKIPPLTGKSLSLHNSHFPRSRICQASQSSGRIAPKPIRAKFQQSIWAQKAQKQQRERKKPNVLMTFLKRSRPSDLRRRPPGKGAQLKAGAEGKGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WWX1</accession>
    <name>A0AAV4WWX1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_17505_1</name>
        <name evidence="2" type="ORF">CEXT_811511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016795">
        <property type="protein sequence ID" value="GIY86435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WWX1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="195" mass="21761" checksum="0DE960461BCCC0B0" modified="2024-11-27" version="1">MLNIWPAAQSLLRRFCDRVLFKPELCSNTGIGPRKASMDFLRQLDLETIHEILNDALQIYTDVSKDDGADSGELQQRTSSRTETPSERRLSPNTPAACPNSSPSRRNSDRRKRGFVRKNTQSAPDSFDNDDDSYTGVPTITHTSSDSVDGSTKRKEGQSIGYFNFDSMQRLLDLSITASTKPEKPTFLLTPGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WXH3</accession>
    <name>A0AAV4WXH3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_626791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016782">
        <property type="protein sequence ID" value="GIY86344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WXH3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY86344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="200" mass="22709" checksum="64D48E2DD87B0A25" modified="2024-11-27" version="1">MPSHSTHPEPPNPMHPFLDSESETHLRIQFKAWIVQRAKASTSFPRWGRERAEEKGASQMAAFYFAAAAAYRSPRLPGSLTPTEVTVVHARRFLFRGRLDSGLPLRSLCGESFHSNCSKIEVFSFFLFFLFCSPLLRETRYPFSTCHPTTNTYRSIPFRVRGCRRSVPPSYTLRDAWVETEISAVCCEETPPPALCFGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X3R9</accession>
    <name>A0AAV4X3R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_715421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017106">
        <property type="protein sequence ID" value="GIY88820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X3R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY88820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14365" checksum="6A4AE5BF8CF210E9" modified="2024-11-27" version="1">MFAYIALFSLKSKVPQAIFTIESAMKYGMRTPSSHIYTQVKALPGNIYDLLHEMRKKRKKKKKKASSVHSSWEMKTPHVGIFQCSFSWKPSVIRKPKLEGFTEGFSRRFRSVIFFFLPFIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X4W4</accession>
    <name>A0AAV4X4W4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Importin subunit beta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KPNB1</name>
        <name evidence="11" type="ORF">CEXT_733701</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the importin beta family. Importin beta-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017107">
        <property type="protein sequence ID" value="GIY88829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X4W4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000027">
        <property type="entry name" value="Importin subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="21"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="409"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY88829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="857" mass="94839" checksum="227797314FF73186" modified="2024-11-27" version="1">MDLISILEKTVSPDKAELEAAQNYLEQAAQNNLSEFLKSLSSVLQHASNSPVARMAAGLQLKNALTSKDPEIRLQYQERWSQFPPDVRGYVKQNILSALGTETLRPSSAAQCVAYVAVAELPRGEWPDLIAMLTQNVTNANSTEMTKEATLEAIGYICQDIDPEVLVTQSNDILTAIVHGIRKDEPSDHVKLAATNALLNSLEFTKANFEKESERHFIMQVVCEATQSSDTKVRVAALQCLVKIMSLYYQYMEAYMGPALFAITMEAMKSEIDEVALQGIEFWSNVCDEEVDLDIEATEAAEQGRPPARTSRFYAKGALQYLVPILMQTLTKQEEHDDEDDWIPSKAAGVCLMLMAACCEEDIVIHVLPFVKNNIKNPDWRYRDAAVMAFGCILEGPEPANLKPVVEQAMPMFIELMSDESVVVRDTVAWTIGRVCELNPEAAVNEAYLKPLLEALVKGLTAEPRVAANVCWAFSSLAEAAFEAAEVPDENQEPNTYCLSEYFEIIVAKLLETTERPDGNQANLRNAAYEALMELVKNSPKDCYVWVQKTTMIILERLNHVLALETHIQNTSDRAQYNDLQSLLCATLQSVLRKMTPEDAPKISDAIMAALLQMFSSTGKSGGVQEDALMAVSMLVEVLGETFLKYMDAFMPYLAVGLKNHAEYQVCTAAVGLTGDICRSLSMKVLPYCDEIMTMLMENLSNTAVNRSVKPQILSVFGDIALAIGPNFRKYLDIVIQTLLQASQTQAEKNDYDMIDYVNELREGCLEAYTGIIQGLKGDQNTPNSEVNIVQPHVPYIIQFITHIAQDPDHSDGTIATSAGVIGDLCLAFGQSMMSLVDNDIIMQPHDLFVVDSVSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X524</accession>
    <name>A0AAV4X524_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_773861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017116">
        <property type="protein sequence ID" value="GIY88893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X524"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY88893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24244" checksum="BBB4B69A5366C0AF" modified="2024-11-27" version="1">MADKRYLSKLFARDIFSSSRVIQITRPQAVPLPPDGQLASALAFGTTGFSVEDALEVLRILSPPSSWHEPGSVQESEDSGKEGHPSHNALACHQQANRGWTQRPRNLGLSPALPHGHGIVHLHAATDVPDGDERRRIEPHPVLHRGWIGRRYQQLDSTQKGHLQDLEDRFRRRLAERNRKTSQSGCSEVRRAHSSLIGSRTWRVVFVSGHFERQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X7U5</accession>
    <name>A0AAV4X7U5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Synaptic vesicle 2-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">svop_4</name>
        <name evidence="9" type="ORF">CEXT_481741</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017305">
        <property type="protein sequence ID" value="GIY90245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X7U5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY90245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="369" mass="41867" checksum="F36C4B27860DC9C7" modified="2024-11-27" version="1">MLFKGILHKILLKKPRKDDGMTLCSEFIPGRYRGRFIFILSCFFAVGVILMLGILYATTRPGHFYWRLFTAIATVPSLIAMIMMRFFPESIRFLLVNEEYVSARCIADEMSSENRKPLPRGQLFPVRNAGKRGNCCRLLEPIHMRSTLLFWYMGIAAGISYYFLIEVSSLYLNDVQSNIEEIHSAAHSFMGNLSQPVECLKNITDAQYLRILWTNALDFPGFVVFMIVVDVMDRKKLLCASCLLCSLFIFLLFLPNGDLVMRAGFLFCARTLLLGEMNMLHLMTAEAYPTTERGIAVGMQTVALYVGFFVTPYVEEGLLMLGVRWVVGFSAGGHVPVGDRSCFSHLGDQRNGTHGHNRRQILRICEKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X896</accession>
    <name>A0AAV4X896_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_791501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017384">
        <property type="protein sequence ID" value="GIY91136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X896"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10224" checksum="0561117262B06727" modified="2024-11-27" version="1">MVIRFYGVNLIGSPGVSLLLLALVGFSSVVNFRIVDGIMRRTKQENVTEGNALQLSKEVPMRRGANERFLSSIQFCLNFYSVSYDIQSDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8M4</accession>
    <name>A0AAV4X8M4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_604981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000029">
        <property type="protein sequence ID" value="GIY91611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY91611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10432" checksum="4D1B94A5B4279B92" modified="2024-11-27" version="1">MKSTEKETLYLHNACTNRGKQYFPPKKAISKRGKRKKRKEKAASAERETLEIHGWLNISHDEQPGARDLEVCQRGSQSVRNPMSEPDYEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAG5</accession>
    <name>A0AAV4XAG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_19241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000026">
        <property type="protein sequence ID" value="GIY91592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="189" mass="20651" checksum="79F9942EA5D280A9" modified="2024-11-27" version="1">MITSSSECRRFAKHPVSLSPAGEAGQLSIIIRTRAPSFPNRIIVIPGPGLIARRQLRAQVAMGACDIPKWPCGRDPLLCSVVRNNRNRYGNAAKRIVAISPEPIKPIGWPLLFSICSAFIGTARFGDKAVLFNKGGLIVVPRAHIGHSGDRWVDVVVRHQCLVRQTMSCISSLVKILVNPEILTSLNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XAY3</accession>
    <name>A0AAV4XAY3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_167101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000088">
        <property type="protein sequence ID" value="GIY92066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XAY3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8459" checksum="2ECE9482B325F1AD" modified="2024-11-27" version="1">MYITRLSSPIISVEVRCSLTRGRVVDEGEQKQGSLSSIPHLSGHPGGTRAVPLLLLPGCGKSFGRWPSSARISLLSTGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XD34</accession>
    <name>A0AAV4XD34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_362641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000128">
        <property type="protein sequence ID" value="GIY92348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XD34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7800" checksum="F9CC1F191406C0BC" modified="2024-11-27" version="1">MVRKPTTRFHCDFNVAVVLQRIRPWGLVTDQQNDATWFIAVLCKTEPHSRFLAVKMTSLSCAEFALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XEE9</accession>
    <name>A0AAV4XEE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysosomal-trafficking regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">LYST_0</name>
        <name evidence="2" type="ORF">CEXT_307161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000107">
        <property type="protein sequence ID" value="GIY92164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XEE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="265" mass="30419" checksum="0BBC3876341D234A" modified="2024-11-27" version="1">MRQTIQVFLNHSKKYLLEGRGWKILWTLENIGIQNLLCLKDLIKLLILHVPVLLSLPVCISSIPVLLQRKPKCIPLSSCFVLSKRNKNVPYNVDFRWPENYDDQVLFEPCPVPASQLVTLQKVHRIDSPCVPKSPSEVMESDQELSSIDPSLPLELQDFRCYVISVMDYMHFILNLFQETAELDRQNSEYTSCSAPLILEFSLNALKDIHNGRYAFQGWPKEDIYSIQNQLLKLVFLSATVTYSGLSYTGAPNENKSDLYITNCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGW0</accession>
    <name>A0AAV4XGW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_214251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017761">
        <property type="protein sequence ID" value="GIY94255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="57" mass="6297" checksum="DE9887D6953E25BE" modified="2024-11-27" version="1" fragment="single">MFPPENLDKRSPAGVKSTTSFMPQNSKSHRRFALYGPVNKSPSVTRTAIVFSAWISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHT9</accession>
    <name>A0AAV4XHT9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_330441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000282">
        <property type="protein sequence ID" value="GIY93614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHT9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043842605" evidence="1">
        <location>
            <begin position="16"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY93614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9121" checksum="398862D140853D45" modified="2024-11-27" version="1">MFVFAFLACFALAQASLLPTYSAGVPLVSNLPLVSNVPYPYGVVAPGLGFGFNNGYGFYDQKIQCFSPWLQRCVGVQRIPRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XIV0</accession>
    <name>A0AAV4XIV0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_375321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000296">
        <property type="protein sequence ID" value="GIY93724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XIV0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10142" checksum="D4B9E3DE99CD1F9C" modified="2024-11-27" version="1">MSFRRLEDKLPSHTLAVSDSDFQSLPRPELNLISERCGGWKEPFSGNKTQFLLLSGCQKYFCTHGSDFSVSFYAKISPIDLNPKVKREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XK40</accession>
    <name>A0AAV4XK40_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_240351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017901">
        <property type="protein sequence ID" value="GIY95366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XK40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY95366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17467" checksum="DE0597450878BD94" modified="2024-11-27" version="1">MRSLQFRSRIGFVLIPYTFKRDLQGLDIKILINIKLHILMRSSSHNKDQRTAGLPTRQHNVHFFLEHRCHCMETNAERKTAQSTATTQRPSQPRNTCPAYVCMCARSSDAYLNAGAWKGKRVEAFRFLPQGHLTPQKSKILLEGFLSIDIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLC4</accession>
    <name>A0AAV4XLC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLC25A11</name>
        <name evidence="9" type="ORF">CEXT_206091</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017981">
        <property type="protein sequence ID" value="GIY95932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY95932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15270" checksum="5DF55AAAD60A2B46" modified="2024-11-27" version="1">MGVYSTLFEKFSGDGKPPGFFMKAAIGMAAGAVGAFVGTPAEISLIRMTADGSKQKHKENNSNSVLLVFECASVTTFHCILFLWLPCAYCNVCGKIPIAMSTDLIENTPSITAKRQLPSRHHLTYSRQMNLHESEKAAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XM72</accession>
    <name>A0AAV4XM72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_6781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000439">
        <property type="protein sequence ID" value="GIY94833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XM72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="145" mass="15845" checksum="950D7D6CCBD320B0" modified="2024-11-27" version="1">MAPESELSSPLVVISDLFLLRRVKGRTSLLPCEDEGCPPAVLGVDLQTSGKTYLWRHGDSGPKNGSYLGGHGCPLREHLGLLGITNRRVYLCSRRLTYLQWSLLPLHGLLGLQPVHRLLHLDALPPIGSGSESKISPKHDISEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSR2</accession>
    <name>A0AAV4XSR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_453111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000902">
        <property type="protein sequence ID" value="GIY98245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10610" checksum="E3AF1E0E005ABCC4" modified="2024-11-27" version="1">MSRCGVNVHPAKPPGAFPAPDKSDSMEAKRRRVKMAPDRSDSSGGKMGVILALLESVECRRSQLKDRLYQEIPRVIHHRVMFAELLEIRTKRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT36</accession>
    <name>A0AAV4XT36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_337031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000771">
        <property type="protein sequence ID" value="GIY97340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="227" mass="25302" checksum="125A53D3EF204CE0" modified="2024-11-27" version="1">MFSPRRTAGVGIREEPSSCFEVCRGESVETHSLWKEDCHWKRLQFSLACAFRHSGLEKVEKKKKCAICLFRRNPRASVNLINPKPDTSPSGWLITGHRQREQRLISKNAGGLHKGGCSHLVGCGGGRGLIREGPLSCFEVCRGESFRDPFIIEGRTATGNVFRSHPFVLFSIQDWRKGRGGVCVGRICAVCLFRRNPRVSVNLVNSKPDTSASGWLITGHRIVKISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTC2</accession>
    <name>A0AAV4XTC2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein 117</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TMEM117</name>
        <name evidence="3" type="ORF">CEXT_207641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018295">
        <property type="protein sequence ID" value="GIY98455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTC2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070059">
        <property type="term" value="P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029370">
        <property type="entry name" value="TMEM117"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31226">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31226:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15113">
        <property type="entry name" value="TMEM117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="498"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY98455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="687" mass="79737" checksum="2D89CDEF8E0EFD98" modified="2024-11-27" version="1">MLCLYLNDTRCQVHQKPNEAFHRHCVEGQVEAMMFYGSIVYCTLRKENEYEGSSTQFGAQSEFSRPWTNHKSVRKCHLKSDSGSKIKHETEGNKNKTTPIDIGKSGSGTEDGPAETSNENHLEDIKYIDDSAKSSLSTSLTEAPVPVLQTQQQQQQQQQLPPPSTNCPQSPQQHLRDLVPLHEPRLVVSPLPSEKLKQEKDGGHSETDYYSRNSIGESEHQVTQTLYIEKDFRYYFQHPYSRLFVSYFVIFCNFLVFAEDPVSHSHTESEIPFVGHVFSFVATKYPPQWSWCILKVILWVIAIISGCFFGKYLIHHLLLIYNWFLQFGHPLYEAFHINSHMGITNANFMKAAASGTWIGDFVTAWMVTDMMLQDNLYPNWARPYREFWRSHGRIRIVIFWLGSIIMTALVVTLIVSDLISWDNLNRDFVATTELSRAFLASFILVMDLLIVMQDWDFPHFVCDLDIKLPGMHAASFKFELFQKYVNLPDVSIHVTGKWFNYSIIVFVMILDLNMWKNQIFYIPSEYGQYTGPNHKVFSIPDLDLLVANNYTLWTYEIRNTQIDPNTNRTLLEGDISMNSRYLGYPLSVKGMAFMPSLIGFAMFGILTYLYGRFPPPTERLVYGRHRKRKREVPRSSWRRERGNRCTHYLIHNKEKYPEEKRKGNPLTELIVAWEENLGPAKQCEKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XW58</accession>
    <name>A0AAV4XW58_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7153 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_182941_1</name>
        <name evidence="2" type="ORF">CEXT_116121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000898">
        <property type="protein sequence ID" value="GIY98204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XW58"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055577">
        <property type="entry name" value="DUF7153"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22198">
        <property type="entry name" value="FERM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22198:SF1">
        <property type="entry name" value="FERM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23672">
        <property type="entry name" value="DUF7153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7153" evidence="1">
        <location>
            <begin position="62"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="235" mass="26827" checksum="FF0C915212405748" modified="2024-11-27" version="1">MRVVPIPERKYHVILEFEESPEPPKMPTSSSGLMVVTPDITASTRDQMLLFSWLRESHVAAMGMLLVNVERLTEFPFVTYLVVNGGRHELSQRLQSVDSRPIPENIRQRHFLAGYEETITITKPPLTFPEKPPSDKTGFVVSLYQVLPGEDGLKFEQNWVMWTGARQLYRTAPEHLGLKRISVHKSVLPTKIINYCLLCEFSNIMAHLTDACVMIDHLRARCCGFTGIYRILDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XXB7</accession>
    <name>A0AAV4XXB7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Mutyh</name>
        <name evidence="15" type="ORF">CEXT_233581</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="BPLR01018399">
        <property type="protein sequence ID" value="GIY99223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XXB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035485">
        <property type="term" value="F:adenine/guanine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032357">
        <property type="term" value="F:oxidized purine DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000002">
        <property type="entry name" value="Adenine DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944:SF1">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="14">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIY99223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="21336" checksum="608F53C33AB43F7D" modified="2024-11-27" version="1">MLQQTQVATVIPYFNKWIQKWPTVQALADAKVEEVLQTWAGLGYYSRGRRLHEGAKIIMEKLNGKIPDSVSELTKLIPGIGAYSASAIASIAFQKPAGVVDGNVIRVLSRMRIIGAHVSQPGVRDHLWELANKIVSKKRPGDFNQSLMELGATICTPQNPNCASCPVNKYCHAYNMTKTTPTAGKIEFIFEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3R6</accession>
    <name>A0AAV4Y3R6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018698">
        <property type="protein sequence ID" value="GIZ01650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3R6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="27730" checksum="466BC930E449C2B7" modified="2024-11-27" version="1">MFRKTITGQSDGRVRTLHTTPLRQIYLGGVGLEGGLEEDSPAGVIFRPRSYHLKKSAGPSSLPDLVRKVAKKSEEKVGRRTQAHCQTQLESGLGLPDRWKGAIRQSCGSVASYLPSHDEQEGGTGLVRVRCRGPVRVRLLPELPDWGLCSRRPGGRGRESGRGGAQSSGRPLRRMTSGAVPMAHPASHKSYRPLTVLTFRTDLVFLNTKLLQKFHVYAVVVACKLSTWIFNLNKRPVIDCAFGNETSLFAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y6R9</accession>
    <name>A0AAV4Y6R9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_592621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018898">
        <property type="protein sequence ID" value="GIZ03062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y6R9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="322" mass="37150" checksum="2DEDB839E3FDC48E" modified="2024-11-27" version="1">MFISQFGDTFREMSLLVQNGQMDAKNVALKRDCEMGGLKNVTGGDGEKHSVCVIGKKSDSLDIGERNERWRKGYLGPPPHPHTLPKHHPDIHFPRKKRKKRAEVIERSFSKENESLHFVSEQKYVHFTVWRCISRNVNSRSKWSDGCGLPRMSPEKGLWNWQLKNVTGGDAAALTFPLAALLEKPALWTSENKRWAKGLILYPSLPHTILKTPPRHSFQIKKKEKRPEVIGRSPSKRKMSVFSFRGQNRNMCISQFGDTFQEMSFLVQTGRMDAACRECRQKRDCEMGGLKMSLEEIEKNTACVELEGWLLFFLFRCWAFRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7F0</accession>
    <name>A0AAV4Y7F0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Dscam2</name>
        <name evidence="4" type="ORF">CEXT_169481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018934">
        <property type="protein sequence ID" value="GIZ03332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7F0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF6">
        <property type="entry name" value="CONTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="198"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIZ03332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="270" mass="30654" checksum="066D4A248EC341E4" modified="2024-11-27" version="1">MGYTGPKGLQISAAVESNRESTPHPFYLSKLKLKFLPSQTLIKTIYKMVGTRRLYNTIWWLSRLLSGILEIVNQKYEIRLSDEFVLRGNMALLRCPIPSFVSDYVKVTSWERIDGFLITLESLVLPFHAIKLIQCLFFPKAGKYGILQNGDLYIRDTTEHDSSYSFRCHTENSVTREKKVSTNYSKIIVTEPHHNQPPRIMRRSSRVSVPVGQKATLSCLAQGHPVPTYRWHKVAGELRSLPELGSSVRQEGGVLVFHKVVSADGGTYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7M1</accession>
    <name>A0AAV4Y7M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_614791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018890">
        <property type="protein sequence ID" value="GIZ03015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="11957" checksum="761E609CFA8CF413" modified="2024-11-27" version="1">MTGFKKTAGPKFEIPLFRKALFLSPEPRPKCQTLAKFIIRPVIINALHPTILRQSRRTNHRHPSNCCCRHHGRTVILAKADLLIEDITTAKAIKQDQPLPRRAGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBA9</accession>
    <name>A0AAV4YBA9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein quiver</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_12766_1</name>
        <name evidence="2" type="ORF">CEXT_481591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001633">
        <property type="protein sequence ID" value="GIZ03656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38332">
        <property type="entry name" value="PROTEIN CBG11604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38332:SF1">
        <property type="entry name" value="RE49668P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="19094" checksum="6E9C1A2D26EF9C25" modified="2024-11-27" version="1">MNLKDVSDCSKVSSIFKCCCFYSIVLVLLLLLKGSHSLDCFKCVSVGGDNQPCEDPFHNNYTKDILEAPCWAGRKQRDGVFPATACIKLSGIYEDTGETMIVRGCALDSGTLTIDTEIVRMSHCGGFYFDNRYVSGCLQSCSEDACNRSVSIYSWKWMSYLILLITLTYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YCF8</accession>
    <name>A0AAV4YCF8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tax1-binding protein 3 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">txbp-3</name>
        <name evidence="2" type="ORF">CEXT_757561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019165">
        <property type="protein sequence ID" value="GIZ04902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YCF8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014069">
        <property type="term" value="C:postsynaptic density"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045197">
        <property type="term" value="P:establishment or maintenance of epithelial cell apical/basal polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098968">
        <property type="term" value="P:neurotransmitter receptor transport postsynaptic membrane to endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098887">
        <property type="term" value="P:neurotransmitter receptor transport, endosome to postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043113">
        <property type="term" value="P:receptor clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10822">
        <property type="entry name" value="PDZ_TAX1BP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050614">
        <property type="entry name" value="Synaptic_Scaffolding_LAP-MAGUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017268">
        <property type="entry name" value="Tax1-binding_p3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119">
        <property type="entry name" value="DISCS LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119:SF50">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tax1-binding_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="17"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ04902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13335" checksum="2F56F31F336CE69F" modified="2024-11-27" version="1">MAFEHQPGMAIECLSIPIKLTKETSNDSEGREVLKCGFKIGGGIDQDFHKSPYGYKDSGIYVTEVYENSPAAKCGLKIHDKILQVNGYDFTMVTHNKAVEYIKKNPVLNMLVARKGVTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YDR6</accession>
    <name>A0AAV4YDR6_CAEEX</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">CEXT_320001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
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            <taxon>Arthropoda</taxon>
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            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="GIZ04312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001054945">
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    </dbReference>
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            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="GIZ04312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="158" mass="17764" checksum="1C48AB4ECCF80D0C" modified="2024-11-27" version="1">MEITKCKYCNANVTNSEVHNCVKFGNQHRRTSATLPQCSSGNVSEDIGLITAQEMEDDALWPFVRQNCEETSAAEMYSWYDVSNQDQYNPANSDFHFPSKPYVEENEYKSVNLQHSSEPSQNSQLSDASNPGHPENIPTSLAQQGLLPGLQQTFDQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YFR2</accession>
    <name>A0AAV4YFR2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_516891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019204">
        <property type="protein sequence ID" value="GIZ05094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YFR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ05094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="275" mass="30870" checksum="7DC94567F2E1E6C3" modified="2024-11-27" version="1">MSASGIAFRSPHSLTAEIILSSSLLSSTPAIFIEHDNSSQSTSTPSEILMTLQMPHLSEEMKDQKRQFDPWGGKKRSHQHKRQFSPWGGKRSPVSQLESSANRYARDASMKNSPKKRSFNSWSSKNPFLQKSGISVHGTVKEILIRGVPLGWKRDLFSPLGWERDRLTLGLERDRLTLGLERDRLTLGLERDRLTLGLERELLTLGLERELLTLGLERDLSIHGVAVKNLSILGAERSLLALGVGKEALTLGEGTHSTTRRQFHTKVRWKSISTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M463</accession>
    <name>A0AAV4M463_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_82551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019331">
        <property type="protein sequence ID" value="GIX66657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M463"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX66657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9108" checksum="F781102A0C1D80D9" modified="2024-11-27" version="1">MSCYQAMHSCLLNSFVARWVSHCLWRLAVHGSEEITSVTQCCDIIHSQTSSDTRPSGNMCLAAGGRVPLTVTHKEESAACEVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M5B3</accession>
    <name>A0AAV4M5B3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_15026_1</name>
        <name evidence="2" type="ORF">CEXT_575782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019369">
        <property type="protein sequence ID" value="GIX67040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M5B3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX67040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="688" mass="77754" checksum="A308B0D0CCD9597E" modified="2024-11-27" version="1">MESMLKILNECLLNADIQSVCKADLRKKYLEKMGLNKLPKEDKELFSSAVETAYKIFVLSSNKATNVSTKMEVDPSYSDDEPLESIRNTQLKRSQSDFGKQRVQKLLISSSEDDFSDQEKIIKNTQKASKESENNNNSLEKSSMKHSIIESDDEPISKFSKHKFNNSINSEDESLAKLSKKKSRDSSDSDAPLNTLTKRKSNSAKRICKSNKESFTKSAKKKNSISSDSDDEPLITLSEKKIDSFQKPLKSKKQKSNVNKKISKSVKFDSSDSEEPLVNLAKKKFNKKRKTRCTDSDDDNFQKMANKKKKSTAVKELLSDSSEDEPLVRFTETVSKVSSDSIDNDSLKVADREMKQNNVKKKLLLASSSSEDEPLSKLTKNDPNDSENDDDLRAANKKESQSVDIKEKITSAASDSNEEEPLSKFTKDDPKSSSDSENDDDLRVKNKKERQSVDRKAKITSATSDSNEDEPLSKFTKNEPKSSTSSDSSKDKPLSKFTEKDHKSSRDSSEEDENEISSRKSKSLERSSSLSVDENEKSNTKIQQSKQSQKKKEIPRILLVDKKRLSASENKLEHLKKYVRAAGIRIQNYTKLFENCKSMKAKCEKLISLLEKEGLKGRPTLEKCKKLKMKIETKREIAELDVSNILEVKGRRTKRSACSDATNCKTNETTTAIKFSRLQDIVDSEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVD4</accession>
    <name>A0AAV4MVD4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Ras64B</name>
        <name evidence="6" type="ORF">CEXT_328081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Lipid-anchor</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020248">
        <property type="protein sequence ID" value="GIX76374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVD4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX76374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14525" checksum="96D6169735C3AF0D" modified="2024-11-27" version="1">MREQYMRSGEGFLLVFSVTDSNSLDEMYRFHRQILRVKDRDEFPMLLVANKCDMESQRVIPSDEIQQRAEQLKIPFVECSAMLGRNVEIAFHDLVRQVRKFQAAERPPIKPSKLKPRRKCVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MW34</accession>
    <name>A0AAV4MW34_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_169001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002675">
        <property type="protein sequence ID" value="GIX76573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MW34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="73" mass="8155" checksum="0989C7AEE5A9A1C1" modified="2024-11-27" version="1">MIRTLMLRPENAIRSSTSIRDPAPGPRKDISGNFFATSARMVVNPNAVAFQPQRSSYTPPLAINLNSMEFFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MXG2</accession>
    <name>A0AAV4MXG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ammonium transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">amt-3</name>
        <name evidence="10" type="ORF">CEXT_81481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020220">
        <property type="protein sequence ID" value="GIX76047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MXG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF58">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="6"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX76047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="397" mass="43299" checksum="F8F893CFBDD29336" modified="2024-11-27" version="1">MGVVFATFIFQLSFATTATTIVSGAMAERTDFHAYCIFSFLNTLTYCIPAGWLWAEHGFLKHLGALDFAGSCAVHLTGGVSALVAALMLKPRLRRYDNGPDPLPMGNPGNALVGTFTLWWGWLVFNCGSSFGISGDKWHYAGRSAVNTINASLGGGLAGLIYSYTKTGSGFLRSWESLVVGAFGAILVSIVAPLMDKYRIDDPVGAVAVHAMGGLWGMIAVGLFIDNDSLLNLTHGRSGLFKGGGFYLLGVQILACVAVSIWSMITTFLILKSINYFVPIRLAPPEEILGADFVEHDVRHEGYDYEVMMTELERLGLKLRHPRIHNPPRSQWDDHLILQYIEKVLVKCDSNDSSTDPLTTNGSSPPNIIAQEHFLSVEAVEQMAVLYHNSDLNGTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0P7</accession>
    <name>A0AAV4N0P7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_413331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020355">
        <property type="protein sequence ID" value="GIX77751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0P7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX77751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12285" checksum="C058FFB11295F7BD" modified="2024-11-27" version="1">MRKEIPSFMIFELSINTLTGIVILTSLTFCCSKIPELMIKIKIAVAVLIDKHEANDLIGSKEVRLLKRMEKKEIIYMSACDMIYFKKGFLLSACGTLFTYGLLIVNMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2Z0</accession>
    <name>A0AAV4N2Z0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S1 motif domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AVEN_185463_1</name>
        <name evidence="6" type="ORF">CEXT_130431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020373">
        <property type="protein sequence ID" value="GIX78026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2Z0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="311"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="387"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="438"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX78026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="488" mass="54939" checksum="BA58A8A2290F83DF" modified="2024-11-27" version="1">MNENSFSCIKQVVKTIQLPLPFAFISNEVASITEILDSWKRRYVKQLKGVIVNYKNISLCSPGSVGFTSPYIHYKVTATFDLFCPNVGDIVKGKINYISREHIGCLIEGTINVTIYLSQDSSPELSQFIYLNNDILFEIVNFDYERNIIHVRGDITPKCILLMKHFLHPESYSNNHVKYSLGDGVDSDVSDDGIGSSIDTCISNAEKDVNFKKPLSSKKKSKTKSHKKHDNECDSLIESFSQADHIQVFQSIKQERSPVKTSSDKKKNSSTLFESNNKSTEISVPNLLLDSSASTNSTEVVGTDSIDFTKIKKSKSPKKRKRESEPLFMDTSIMSMVDEMPKKKKRKKSDVSDEKKVELKNETSTHLSLDTLENNLLNQAIKIAHHGDVPATTKKKSSTEKDKKTKKHNKKKQGSSDKKSKDKNKSKKKGKVLASGSVRKKDKKNKSKDKHVKKHKKSKGHKKDKNEKKKGKKKSGSKTDTVIKSEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3T8</accession>
    <name>A0AAV4N3T8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_520121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002930">
        <property type="protein sequence ID" value="GIX79363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3T8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="199" mass="22051" checksum="719AD6EA8A3B7A24" modified="2024-11-27" version="1">MDDPLNASQTDISRTTVWFARVHKNFSDYTSLKSRSSVGRPRSTNSVVMEENTLDSIVTNHYTSIRTVASAIKEARFGFLSLNPYTPFTAKGSSCCSLMIILHICFSYSGHSLYRRIGCSSPVPWTSISPDLSNLDFFLVGALKAIVYHGSVEINLVTRVFTAIIITETVGVFDSDQLSRLRVFQGYLASDGANFELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N419</accession>
    <name>A0AAV4N419_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_288051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020389">
        <property type="protein sequence ID" value="GIX78134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N419"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="14372" checksum="070C74BAD2B4C84C" modified="2024-11-27" version="1">MQLLIIIFSQILKYSFQFIGRETLLRFVCQTLIGSKGLSNDCACMAEFTKYCRECSCQSYKMGDSVEFRNYRFETNNSQLPETISKLNFSPKQDFPKPIWPKEKILAHASNKICVETRNEFMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N4F5</accession>
    <name>A0AAV4N4F5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_102421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020472">
        <property type="protein sequence ID" value="GIX79170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N4F5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="15266" checksum="07CE8C85CF453785" modified="2024-11-27" version="1">MPACSTNASSCSTRLVIFSIFSRTHHHMRRERSFSIVLRNLPNVKSVHKQYTLKTKISMNIAWNVIKRMTRHFWFDLLEISPLNKKKKKHYRPHGSSWDFYCRDSSYRMHFRKVAVKTPAHYDFGFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N7B1</accession>
    <name>A0AAV4N7B1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 4V2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Cyp4v2</name>
        <name evidence="10" type="ORF">CEXT_349841</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003048">
        <property type="protein sequence ID" value="GIX80593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N7B1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX80593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="461" mass="53135" checksum="BB05AD667DE01FC2" modified="2024-11-27" version="1">MFFEIVVCAFIGIVSVLALLTLWRKKYNRFVPDNKHSVFQVLLDVVDFILFVTSGKKNAFHLYIIKYFTEKSKKFRHCPLFMHWLCGVPLVIIHKAEAVKDLLKEKRIIEKSHFYDFFKLYIGTGIFTCDSSQWKERRKQLSAGFQSSMLKGYLTVFNEHAQKLVEYLQGETGKEFTCVERTLSLCSLDTVCESILGVKIGALQSEAEEYASSLQDVAMSRIWKFWLWPDFIFFRCSNIYRENLPHLRIAHGFSRHHKKERKLRYMKGEMGDDSRRPKCLLDVLLKLHIEDQVFDEEGVRQEVDTFISAGHESTAVTTKWALYLIGLYPEVQEKIHHELDSVLGADSKGPLSVADLNELKYLECVLKESNRLYPPAAVIARKISEDISICGYKIPKRTQVVVSPFLVHRDEDVFPDPEQFDPGRFLPENSVNIPDCAYIPFAAGPRGCIGKRLELNLSTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAT0</accession>
    <name>A0AAV4NAT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_775061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003052">
        <property type="protein sequence ID" value="GIX80637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9597" checksum="5AE5F5DF0F7412C2" modified="2024-11-27" version="1">MQTVPQNSRQGEHVVHERIRCQRSAIIRINSSSDIAILGTECDANGIFVRRNCEPRSLVCFMDLRSVSLLWDSKWMISKGKSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCH2</accession>
    <name>A0AAV4NCH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_812811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020783">
        <property type="protein sequence ID" value="GIX82427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="19061" checksum="9FAC10B55E2872F5" modified="2024-11-27" version="1">MDSDQRNRERGNFSGNLSQLIPKLYGLPSTQRIKVPSFPERCWREHFFACCTEEVLAQYITDKNKESRSPQSLLPVIIFINIYHRNRCWLEVHETWKIISFISRGYRAGVIFHRILSCFLASFATVKGRVNLSRVILRLDLMHYRMAKGIHYEDVVGIKTGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDH5</accession>
    <name>A0AAV4NDH5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_537751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020681">
        <property type="protein sequence ID" value="GIX81464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDH5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11416" checksum="6AAF616FD2293BBC" modified="2024-11-27" version="1">MRALITGLIQCSVYDCAESHRQINSRIPVSFRKLRLIIVISGVNFWPHIINTEKRPRGMQSRNIPFHFYDPDCNWRAFTGPQRRRTGNIHEKEKTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NDV5</accession>
    <name>A0AAV4NDV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_372871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003210">
        <property type="protein sequence ID" value="GIX82146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NDV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX82146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13827" checksum="DD850F22EEBE26E9" modified="2024-11-27" version="1">MPRVRVRELIYYSYSTTSDNPPRVKCPSSFVCPPPPATILMALQLTTVSHTKLQFPFLWCVVTPRMKPPKIAMSARPQFLGAMLSAAQQWFFKACHHPTHSLRHQRSKDPPPLLFTPRISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NFU6</accession>
    <name>A0AAV4NFU6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar ribonucleoprotein protein MPP10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Mphosph10</name>
        <name evidence="9" type="ORF">CEXT_642921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the MPP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003355">
        <property type="protein sequence ID" value="GIX83657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NFU6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017300">
        <property type="entry name" value="snoRNP_Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="130"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="298"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="570"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="323"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="587"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIX83657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="622" mass="71701" checksum="0A110E2A858D1A1A" modified="2024-11-27" version="1">METSMCDGMFLNIINNFSDLTENPEILIQKNSTVDDSLKSISKSLHDYISKENSVLGLKSKSLSKLLTKGFDDEQIWQQIDLRNESVLNHLKNSISELENGQIRLDSDTTNLFGDDDNNNDLNNIDHSNISASDKHVLENEPGDVSNSEDSSDEEYTDYDKNANWKLEIDGGSDEDEVKDRLQDTIDSEEFSGGENVENDKNSADLESEGINANINKSKFKNINSENDESDLSDIESSKAQKEVRHKENKFKSIVDDQFFKLSKLEQFLRVEDIKEERARDGDLNESDDEEEEIDYFQDIPDDPNDMSARNCTYDDFFASPGSEEENDADHDEMNDLDGEDSFDNEFDEEDEEEDENEIAEAISKNAKELSKTPYELQQENINKQISEYEENLLCPKPWQLTGEVDVNNRPIDGLLDLPTDFQMNAKPMVIQDKEFCEKIENLIKMTIKNKAYSDPVRQDKPVQETIAFKKEIVLDHNKSKKGLAEEYEEMYLKKKKQKEEEEGNPKHKEIIKCMDSLLPELYALFTHIPKPAVPDIKVVSNLPAITVEEVAPTSYSDATLLAPEEIKKRTGLLKGKTERTDTDRKRERRKKKLHQRQCIRRKRKKIQRISLFLEKERKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NI78</accession>
    <name>A0AAV4NI78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc finger SWIM domain-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ZSWIM6</name>
        <name evidence="5" type="ORF">CEXT_112221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020872">
        <property type="protein sequence ID" value="GIX83495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NI78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031462">
        <property type="term" value="C:Cul2-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048370">
        <property type="entry name" value="ZSWIM4-8_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22619">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22619:SF0">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 6-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21055">
        <property type="entry name" value="ZSWIM4-8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZSWIM4-8 C-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIX83495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11201" checksum="FFC766C64DF52D97" modified="2024-11-27" version="1">MTSSQLFTVARYMEHRGYPHRAYKLAVLAMKGVHLAYNQDNHPAINDIHWACALSHSLGKSELTNLVPLLVKNVQCATVLSDILRRLLNGSARYCYFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK15</accession>
    <name>A0AAV4NK15_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_35393_1</name>
        <name evidence="2" type="ORF">CEXT_171151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020993">
        <property type="protein sequence ID" value="GIX84694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK15"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX84694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12265" checksum="C51AF36E3E158E15" modified="2024-11-27" version="1" fragment="single">EIKDDAKNEFTLFNSDGEEDNFEDDFKIRPQFEGKRGQQVINEVNNEKTKNIKILESILGHEVIEKFPEDKSSVKKRLMRFDPENESASKYLKTSEISEEPVLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NLC3</accession>
    <name>A0AAV4NLC3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_774291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003435">
        <property type="protein sequence ID" value="GIX84536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NLC3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX84536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="14565" checksum="8DF434D002CCEEF3" modified="2024-11-27" version="1">MVPFTLVYCRFEQHLKIVGSNFPEAQGIEATYLGTEDISKQDIAKVYVPFSTEYVKEKYMMHVLSSKPLNTIDDQVFPVRNREKLSMECNFPESLGMDVSSSGSGHVRVYIYVSFEPLNVLEKYVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NZJ5</accession>
    <name>A0AAV4NZJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_67841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003929">
        <property type="protein sequence ID" value="GIX90325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NZJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11227" checksum="45747AF449043169" modified="2024-11-27" version="1">MSLECIDELKGQGFHFVDRGFSGKVTTPADPRTLDWSKDTLDWPKHSPFKVEGGVQLTLVWSSTNRPPQGRRAIDTGLEFQEFLLSNHLFVIFSYQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1C7</accession>
    <name>A0AAV4P1C7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_503301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003887">
        <property type="protein sequence ID" value="GIX89810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1C7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX89810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="115" mass="12894" checksum="D5CE79E1CFA12ED1" modified="2024-11-27" version="1">MSALLLWKPGNCRKGCGTADDKKLVKHVGSHRKTSSLPFSLHVLCRKESNQERVPHGNWRNLTNWTSASSPTEAPTPPTLVGNKVGDGESKWGCKYRLIDIACMYHVKMKVYSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1I2</accession>
    <name>A0AAV4P1I2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_525781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021556">
        <property type="protein sequence ID" value="GIX91087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1I2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX91087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10078" checksum="F55268A8E7BA4A11" modified="2024-11-27" version="1">MSRVVYIRQTQARSPTHSDPERTRYQWYFAGRHGSEKGDMIWGGISLGGCSFKSSIVEICEWLDQYVMSYTSSIGKDFILMVGKSLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P477</accession>
    <name>A0AAV4P477_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_468751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003971">
        <property type="protein sequence ID" value="GIX90828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P477"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX90828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13232" checksum="5B0CACD4A65EE8A7" modified="2024-11-27" version="1">MAIVALSPTLPRATIAQGIKNGVVYKNFTEGVKDECSEVWSGSPIKSGPKSTWKRGGHRWKIRSIHSRNFAPCPRGDPFPENLIPLRRKRNCCCAGKPNRPCSQGNGKRRKRFTRDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PI08</accession>
    <name>A0AAV4PI08_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_696181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004503">
        <property type="protein sequence ID" value="GIX95381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PI08"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX95381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="19731" checksum="AA5E58F1A24688B3" modified="2024-11-27" version="1">MIVTPALLNRFNLDSNPFCNIYNIQQFIILYKLISNNLKMPISLDECATNASPVNENWKENIYTTDAHASDANGTRDTPAIWKHFKMPITHVEYATMPVSSTTAVVSVENLPVTSTSVIVNASTIVPEDTLIFELVFSEQPITAKSVKYFQKFQRAIYRPTLIERLLFRMPSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PIK5</accession>
    <name>A0AAV4PIK5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">csgA</name>
        <name evidence="4" type="ORF">CEXT_606231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004455">
        <property type="protein sequence ID" value="GIX94947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PIK5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX94947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="27367" checksum="C1EDA71591D1A74E" modified="2024-11-27" version="1">MSSKRIANVLITGANRGIGLEFVKQFLNLPTPPNLIFATCRNPGKTAEDLQELAKSNPNVKVLQLDVKDEKSFPVIRQQLEQEIGESGLNLLINNAGIALRNNLENVTKEAMMENFEVNAVSPLLLTKELLPLLKTAAIKVGGNSLSCSRAGVVNITSKMSSLDDNTSGGSYSYRTSKTALNMVTKSLSVDLKPHGILALVLHPGWVQTEMGRKGALITTATSVSEMMNTIQLSNEKHSGIMFNYDGEVIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PPI9</accession>
    <name>A0AAV4PPI9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_117486_1</name>
        <name evidence="1" type="ORF">CEXT_623231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004879">
        <property type="protein sequence ID" value="GIX98243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PPI9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX98243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="13994" checksum="48145BB044497D44" modified="2024-11-27" version="1">MNVSITILELKDLIINSTVYKDAAEFVKEILATAVEKRKRKFELETKRLDNELREILSDLIEPSNFRRKYTLPKLQFIQFGDDLKDWLPFWGQFQHIDKDEEKTPENKLSRLSKQCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRA2</accession>
    <name>A0AAV4PRA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_542671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005012">
        <property type="protein sequence ID" value="GIX99184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX99184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="7719" checksum="1A9D738542021430" modified="2024-11-27" version="1">MVKRKADGRKSGIEQRKRAQEGPGLHREPLTTPQAPSNVPSNDVIESGKDYFALAVISAYLSASLLRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PV16</accession>
    <name>A0AAV4PV16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005131">
        <property type="protein sequence ID" value="GIY00024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PV16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="53" mass="5904" checksum="8955D1546AA7DA58" modified="2024-11-27" version="1" fragment="single">MIPHLLIGRVPDSCEKIFGQCVLPRERRGQDSSRLGEEESGFTFVGGTFHLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PWX0</accession>
    <name>A0AAV4PWX0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_42271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005074">
        <property type="protein sequence ID" value="GIX99672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PWX0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX99672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11304" checksum="137DC091EA7E4AE9" modified="2024-11-27" version="1">MYRVQPEKRNPDSPSRKGPSGVTVQLRPPAFLVAANDPRLSSSLAGERESVLRRNSICRMAVMKRRWLWREIGGGGSLSVFILLICWRVIVSKKEEVNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q805</accession>
    <name>A0AAV4Q805_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAM20 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CG31145</name>
        <name evidence="10" type="ORF">CEXT_365621</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAM20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005700">
        <property type="protein sequence ID" value="GIY04337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q805"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024869">
        <property type="entry name" value="FAM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009581">
        <property type="entry name" value="FAM20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12450">
        <property type="entry name" value="DENTIN MATRIX PROTEIN 4 PROTEIN FAM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12450:SF22">
        <property type="entry name" value="EXTRACELLULAR SERINE_THREONINE PROTEIN CG31145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06702">
        <property type="entry name" value="Fam20C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="FAM20 C-terminal" evidence="9">
        <location>
            <begin position="178"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR624869-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR624869-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIY04337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="236" mass="27787" checksum="C3B9B54E34E62F92" modified="2024-11-27" version="1" fragment="single">NNSRLCKNFSLGSSNEELYKANDLVINTLLKMATMSIKSVEFCIILTLCATYVTTLGSYVATLCSTYVSFSTLCFKVVQLNGKHLRGTQLKLIVTYEDGSEAMLKPMRFDRSRETDPNHFYFTDFERHNSEIAAFHLDSQQCLLPRTLQVLLRHQPCHLRQSRRRRGEPGRHASRNLLMDRKRWRNPWRRSYKKREVALWQKDDAYCQKVKQQPLHNNSKRLADIMDMVILDFFDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QHZ8</accession>
    <name>A0AAV4QHZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Contactin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Cntn4</name>
        <name evidence="7" type="ORF">CEXT_337791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006326">
        <property type="protein sequence ID" value="GIY09045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QHZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007420">
        <property type="term" value="P:brain development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000028">
        <property type="entry name" value="Neuronal cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF6">
        <property type="entry name" value="CONTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="178"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="312"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="470"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="561"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="663"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="775"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="877"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="651"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY09045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="974" mass="107694" checksum="534A7E483EDE3916" modified="2024-11-27" version="1">MHYSGSTVVLSFILQYSTRQFYLDIGTGQQRGTVAGDGEIRTTLGRGGFPAPIIKWKTYYRMLLKSFLFNIRLQHKIGDSATLLCSVTPRGQTPFIFKCSTFWIKESEDMETIEGSSVNLICNAGGTPQPESFGRNGTGDQIRFIFQRWWRSKKASVAYFEARADADEFKWLKDKSHGRETASLICMADGQPPPRYTWKQLDGPSASCAGRCEEGATLLTTPQRADAGRYACEVENGVGEALRKIVNLIVNGHPPKIQPFGVSDVLNEGESTKIRVRDSKSNSVQQWKLHLRSAEFGRKDTYSASLVVKAPPKWVTEPNSVEGLVDSFLSVDCQVSGYPPPAITWTKKNGTWTKQKRWRRNTHHHDSFKEWKSHFFQNFLLKTKTEFQLPQCVSPVAFALFLWLQDASSDSIDEGLPEIQPFNFPPRLSEGSSAKVLCNILHDSGNYTCNAENSVGKSSHTAHLVVEAPPFWIKTPHDVTGVYGSRLDMECAAAGSPRPLITWYKADDVIRDGAGRVVARGNGSLSINILTEEDEGPYRCAAHNGVGGGLSKEIKIVVNVPARFDEQFTVVTVKKGDSASLRCEAIGDQPLSVIWKKESKELRKINGGRYEIFETLTPKGLKSELVLREADRTDGQLYTCLTENPMGKTREASSSWSWSPCHPPGPEGAGGVESERQRLLVVALHGKQSHHQIRVAVLEGCSVRGRHRLEEKIVSSAQTSALIKDLHPGINYGLAIVAENTVGRGSPRTPYPSPPERKVRARNNASVMKIKPSGSPMDVNVDVKGAASLLVTWKPPPKSEWNGKLKGYYVGYKIMQDSGHPYSFKTVDYVPGGVQEHMITSLRKDTEYSILVKAYNSAGSGPPSQDVIVRTLGGDLPPPPIVFVVATSENSIKIQWRSTDTKSQLSGHAIHYRKKGESWQRVAVTSPQENSYTLTGLHGGAFYQLYVTANSDFGEGTPATWSPSKHTPRTTTWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJU7</accession>
    <name>A0AAV4QJU7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_470221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006258">
        <property type="protein sequence ID" value="GIY08487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJU7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11725" checksum="9510ACE9ABF593F2" modified="2024-11-27" version="1">MTKSIIEDVKRITVSKNKESSRDYRIFQELIDSNLKLSSAPLTEDTVMKNILLPCTFKESSLHVEEVVTELSSTSAESRLITESCDCNARRQWDLNFGRFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QME4</accession>
    <name>A0AAV4QME4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_724511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006530">
        <property type="protein sequence ID" value="GIY10489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QME4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="102" mass="11599" checksum="2FE6DC84BB343636" modified="2024-11-27" version="1">MKFDKGSFVSLLDFKVSAKYFFGHGDLGSLFNWWDGIVQVLKGILVSQECSRILSQGYWEDFSINQFTSPKVINDTNIKHAKYVKDSKVTVAVIRCIINTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QPF3</accession>
    <name>A0AAV4QPF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_561311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006662">
        <property type="protein sequence ID" value="GIY11578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QPF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="6131" checksum="787CD9D69355C010" modified="2024-11-27" version="1" fragment="single">MGFIVSKFILPLWSPAGYDVPDPATGLTPRQKNIVQSTWKIVRADAKKNGILLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QV03</accession>
    <name>A0AAV4QV03_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_341811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006723">
        <property type="protein sequence ID" value="GIY11921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QV03"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8493" checksum="3F4C81A7645C22AF" modified="2024-11-27" version="1">MEQRTNSLYWRQSLILKSSPLRRKRRPDLLLSFFILPDQEWPKLSHELTTLIPKLNISLSESQRLTVDTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QV30</accession>
    <name>A0AAV4QV30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_131951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006728">
        <property type="protein sequence ID" value="GIY11967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QV30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY11967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10857" checksum="6A92B3F08EB48419" modified="2024-11-27" version="1">MKFFFCEQHLFSDEMMQSLHHLSDDASACRTERKEIISLWHLSPEINGQRESYFLHHSCQREITRTWDQVSSRSGKRNYKLSINLKRNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QVN7</accession>
    <name>A0AAV4QVN7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_793891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006754">
        <property type="protein sequence ID" value="GIY12182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QVN7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="10255" checksum="148F308CEE985305" modified="2024-11-27" version="1">MGHSLFQVMNLRMVMQECVASGTLGRCLMGTGCHQCVCKNFGCGRDDMCEMLLVDGFVENVVGKKFGDYYMNIRYRPYKSLFYFYIYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R4R0</accession>
    <name>A0AAV4R4R0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_602831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007251">
        <property type="protein sequence ID" value="GIY15591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R4R0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY15591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13471" checksum="7AC08EEE973636EA" modified="2024-11-27" version="1">MGNNRSVLFACTLSSWHVSPQLQLHFGSLSVGCYRESKRTGGPNDTRGWTTSADTRKGTDGKAMSARVCFVWETEKKVVRCAAGDGVGYEIEEKEMMWWRKNTNTKSDDSWERKWNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RDB5</accession>
    <name>A0AAV4RDB5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_604391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007802">
        <property type="protein sequence ID" value="GIY19864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RDB5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY19864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12375" checksum="FDDA79522ADB23F0" modified="2024-11-27" version="1">MLGINSCRQPFEVWVPFVSPLLETEDKKKLQMFPREPKKSPRVLRDQVTSYDRGTPINQRHGQLRMNDGDATCLQDAAALSFGFPAVNNSQGTPWVVQVVNWSFHGQMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJ47</accession>
    <name>A0AAV4RJ47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007857">
        <property type="protein sequence ID" value="GIY20240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJ47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="10296" checksum="9E5407B484C2CF84" modified="2024-11-27" version="1">MEYFIPGIHREHSFGGSFEFGRAETRLPQFANARLCIQRTWRGNRTLRWNISFPEFIGNIRLGGSFESGRAKTRLPQFANARRCVEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RL09</accession>
    <name>A0AAV4RL09_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 18 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">vps18</name>
        <name evidence="12" type="ORF">CEXT_787081</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007979">
        <property type="protein sequence ID" value="GIY21182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RL09"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008333">
        <property type="term" value="P:endosome to lysosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007040">
        <property type="term" value="P:lysosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="10">
        <location>
            <begin position="43"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="607"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="11">
        <location>
            <begin position="831"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="791"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY21182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="953" mass="109646" checksum="1EA04E16E5E681A4" modified="2024-11-27" version="1">MASLFDQYEQAASLSSGYMTGKPVIPEMTTAGIINANLEDDTPMFSKKRINFSPSEYVTHMVISNNKLILGMGNKIRRIDVTQPENFDDIDLQKSTGEKARIYELFLDRLGDNLLISLIHPENNGPLENILLFRTSKKLQQCGKMKGHIISSVAWNPQNSSDNTTGFILIGTTKGLIFETELASGDDKPFFPSSIEQYFKQVFDILILYLQITSSRLFHFMGNANTGDPPVLQNVFNYYKDVPESYIELPGQLQCSKLNLFYPNNKGLPSSFAWMTEPGVMYANINYTAKTPKNLIANGQKLYPSDKGETRSPLAIVLTEFHVLVLFHDRLKVISVLNEQLVFEDIFTETYGALKGLIKDPEKGNIWAYSDMAIYRYRVYKEDRFIWEVYLDNNEYGLAKKYCKNDPVKIDKVLTKQAYNLFKEGNYEESAVIYAQTHTSFEEIALKFLEAGQEGALREFLIKKLKGLKNQDKTQITMIVMWLMEIYLNELGVLRTSDRHTSQKFMELQLEFRNLLKDPRIEKCVSNNRSAVYSLISNHGDEDNLIYFTNLMKDFERVIQYNLQHKNYRAALSVLNEHSRPELFYQFSPALMQTNPKETVDAWIAQDRKLNPVQLIPALVHYDNRTDPRQGSEAIRYLEYCVDKMGVRDQAIHNYLLTLYARLQETEKLMTYLQNQDETDVPYDQKYALRICSELPGLEKACVHIYATMGLYEEAVDLALKVDIDLAKQNADRPEDNDDLRKKLWLKLVSKHVVEKKNDIKRAMEFLQECDLIKIEDILPFFPDFVTIDHFKKYNQHIEGLKEEMEVATQSTEEIRGEIQTFRNKYSMVTSQEKCASCGYPIMGRSFYLFPCKHVFHSICMVAEVMPHLTPTKMNRVSEIQRQLAALVGQEDSASISSVSLMSAAISNKDRLNAELDDLVASECLYCGDIMIRSVDISFLNMSDYPAVLKSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RQR4</accession>
    <name>A0AAV4RQR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_294571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008328">
        <property type="protein sequence ID" value="GIY23869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RQR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="72" mass="8127" checksum="8C3560D6EC139F19" modified="2024-11-27" version="1">MSKNLRSGCGGKKRVGENKSQSQASFPRGTNSSTDKKEKHAERIHAEDRGETPGRSRSRSRYYLRSFNLPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWI2</accession>
    <name>A0AAV4RWI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_501241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008570">
        <property type="protein sequence ID" value="GIY25732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY25732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="14888" checksum="6204CC4FB2311DB1" modified="2024-11-27" version="1">MSRQAIEACLSVCSMRHVPLKVKKKKKPIRVNEMPQRCKINASVFAFLVDHHNILHPVSRAKNEERTASFPGDPLAKTIRHSSEGQGAPSSVLFFCLELSVKLPCLRGKKGACHAKTGGYHHFGHHGSLPDCACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S9G0</accession>
    <name>A0AAV4S9G0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_148011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009046">
        <property type="protein sequence ID" value="GIY29261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S9G0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="16875" checksum="74FBAA6D4B608424" modified="2024-11-27" version="1">MLSRCKNQMLRFHSLFRFIPYQNSSSVGRYIYDEGYSDNYKPPPPGYLDSQGGVGLQGADTEVKVLDHKGMQELVNDMGQSGGQYGQQGHMGPQSAGGSGFKGNSGSKDNDEDSKEDIDEALEELEEENVSCVLRAGRGYLIVILNILVYNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBF4</accession>
    <name>A0AAV4SBF4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_622391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009357">
        <property type="protein sequence ID" value="GIY31324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBF4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY31324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15051" checksum="507974079E83380D" modified="2024-11-27" version="1">MSPFLPCNPSIGECVFLPQRSPLDDNPPHPSFEPPFRESPPSFPICDHRYSDKSCLDRYLRRCHLVKVNSAIVPVTHRVTFFIEIRSHLLQTPRIAILSFAGFVVVDVNTAPRSLIRVVFLFVLKSNGMLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SFH9</accession>
    <name>A0AAV4SFH9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epidermal growth factor receptor substrate 15-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EPS15L1</name>
        <name evidence="5" type="ORF">CEXT_415691</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009520">
        <property type="protein sequence ID" value="GIY32500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SFH9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF176">
        <property type="entry name" value="EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="14"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="121"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="153"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="258"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY32500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="360" mass="40012" checksum="8CC7DC82C410E74A" modified="2024-11-27" version="1">MGMLPSPSQVARSHTALYEAFYRQVDPAETDRVSAVEAAAFLKRSGLPDAILSKIWDMSDPQGKGFLDKQGFYVALKLIALHQNGKDLTLANMNLDLPPPQLQTQSGRNSPAVDWNIKAIERKKYEEMFYSMGPVAGKLAGDKVKPVMLNSKLPLDVLGKIWDLSDTDQDGFLSKEEFILAMHLIYKALENIPVPSVLPPELMTILKRKHSIPGMVQVLPDVLPQGIDNMMTGRVRRSSTPSSDIIGRGSTWIVNAVDKAKFDEMFHTLDTDKDGFVTGLDVKDTFLKSGLPQAVLAHIWNLCDIKQNGKLNSEQFALAMYLVQQKIQGIDVPTTLYSEMIPPTLRPKPSTDIPQDVPYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SHA1</accession>
    <name>A0AAV4SHA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_88021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009647">
        <property type="protein sequence ID" value="GIY33495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SHA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY33495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13285" checksum="216DC2E2DAC63D14" modified="2024-11-27" version="1">MEQLFGKQNRTKGYETTPSELSNLGCSCNGATDKQTLRGMKSNKPLQTRKERTSFFVTFSMSMNGITYKTPFHCANINHDLTMVNWLPYKKAKLAGRIGNVPIPKFIPDMQRKEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SIN0</accession>
    <name>A0AAV4SIN0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">DNA damage-binding protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Damage-specific DNA-binding protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SF3B3</name>
        <name evidence="13" type="ORF">CEXT_24471</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DDB1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009693">
        <property type="protein sequence ID" value="GIY33829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SIN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001721">
        <property type="entry name" value="Spliceosomal protein sap, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.910:FF:000002">
        <property type="entry name" value="Splicing factor 3B subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000027">
        <property type="entry name" value="Splicing factor 3B subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000041">
        <property type="entry name" value="Splicing factor 3b subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="11">
        <location>
            <begin position="14"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="12">
        <location>
            <begin position="446"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="10">
        <location>
            <begin position="858"/>
            <end position="1178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY33829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1212" mass="133801" checksum="876BE53E403B1316" modified="2024-11-27" version="1">MILYNLTLQRATGITHAVHGNFAGTKQQEIAVSRGKILELLRPDANTGKVHTLLTVEIFGVIRSMMGFRLTGGSKDYLVIGSDSGKIVILEYNAQKNVFEKVHQETFGKSGCRRIVPGQFLAIDPKGRAVMIGAVEKKKLVYILNRDTAARLTISSPLEAPKSNTLVYHMVGVDAGFENPLFACLEMNYEEADNDPTGEAAVNTQQTLTFYELDLGLNNVISKHTEPLEEHGNFLISVPGGSDGPSGVLICSENYITYKSVGDLHPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKTMFFFLAQTEQGDIFKITLEIDDDVVTEIKLKYFDTVPVASSLCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAIPLEEGDTFFFGPRALKNLVLVDELESLSPIMHCQIADLANEDTPQLYAACGRGPRSTLRVLRHGLEVAEMAVSELPGNPNAVWTVKRNSDEEFDAFIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLACAQIGDNALVQIYPDGIRHIRTDKRVNEWRTSGKKTIIKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYKDRKEMNSEVICMALASVPSGEQRSRFLAVGLMDSTVRIISLDPADCLSPLSMQSLPNTPESLAIVEMGGGEGSDSSGTLYLNIGLQNGGLLRTVLDQVSGDLTDTRSRYLGSKPVQLFKVRMQGNDAVVAISSRSWLSYYYQNRFHLTPLSYETLEYASGFSSEQCPEGIVAISLHTLRILALEKLGAVFNQVATNLEYTPRKFIIHPESNNLIMIETDHNAYTEQTKEIRKRQMAEEMVEAAGEEEQELAADMAAQFLSENLAENVFGSPKGGSGMWASVIRILDPIEGKTIFKVPLEQNESAFSISLVKFASCGDDQFLLIGLVKDLQLGVRQCNGGLVHTYKVLNEGKKLELVHVTPVEEMPAAICPFQGRVLIGVGSMLRIYDIGKKKLLKKCENKHIPNQIVSIHAAGNRIIVGDIQDSFFYVRYKRQDNQLAIFADDTNPRHITSACLLDPNTAAGADKFGNISVIRLPTAISDEVEEDPTGVKALWDRGWLGGSSQKADVIANFHVGEVVLALQKATLIPGGSESLVYTTLSGSIGILVPFINHEDHDFFQHLEMHMRSENPPLCGRDHLSFRSYYYAVKNVIDGDLCEQFNSLDPAKQKSIASDFDKTSSEVSKKLEEIRTRYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SUF3</accession>
    <name>A0AAV4SUF3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_108381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010070">
        <property type="protein sequence ID" value="GIY36624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SUF3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY36624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8753" checksum="468FD2AB6E2E5DD0" modified="2024-11-27" version="1">MLQTEAPALFLLTGPSFGGLREALWIIWWWLLSFPLALVFSGWCYHTPQGHSTVEYNTVPMHVDYAQIHFLWSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVY8</accession>
    <name>A0AAV4SVY8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRASH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AVEN_30672_1</name>
        <name evidence="3" type="ORF">CEXT_481801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010334">
        <property type="protein sequence ID" value="GIY38633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVY8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052787">
        <property type="entry name" value="MAVS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010507">
        <property type="entry name" value="Znf_MYM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21446">
        <property type="entry name" value="DUF3504 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21446:SF6">
        <property type="entry name" value="MITOCHONDRIAL ANTIVIRAL-SIGNALING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06467">
        <property type="entry name" value="zf-FCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MYM-type" evidence="2">
        <location>
            <begin position="411"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY38633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="857" mass="96896" checksum="161646C65A7B07CA" modified="2024-11-27" version="1">MDAVISGIVHMDNIAAENSVIQPDNAKTRQATRYGVRLFREYCVQHGVDTINNLPPREIAAMLKGFYGQARTKDGQRFSVNSLIAIRYAISRYYRSPMVHRKIDIVKDSAFNDANETFRAVLKDLERESRGTACQKELQMVDMDDRRKLRHYFEHAISTPRGLLQKVWYDLMLRVGRRGRESQRLLNRNSFRIAKTADGRQYIYQVDDEEAGIILEIPGDPLCPVKTLKFYLGRLNPACRALFQRPKEHIYEQDTCWYVNSPVGKNMLATMMSTISKCARLSRIYTNVRIRATTYSPADGKGCIPCTDVPELPVREQDIRQEAKPPEKRPPEIAPKPVQVTQNSHIIKQLNAPIVQACLSVAVSNTLSPVTNAGSFINRVFPIALTSVPKQELLNGQAINIAKPMVEESPPRSCDFCKKELKGGMVLKSSEAGKEYCSTECLGKWLAAEHKELQALPQGENAEKNPSNNNSQADSSSNPKIQKLLTLCSSANLLIPFPSLCKDFTASENEVVTNGDIKDESRSSSPQLIVPDEVYPEAILETVDSDPENLDAAVEESEAEEVVEKLTCDQEVMCQPTMISCAISCKPILKSQGIQTDFSTYFSDSIFRNNSFYPKYIVSSTCCSKDEEVDDVIEEHSVLDGDTYECFDDAQDTNSLWMSVEECDDDEPEVSEYISPVSALEKCEETLIPEPLTSVYSQRGRTTKRTTWDEIAQRSKLQTLWGVKVFEVFLFWLQSRGSRRDFERLEAVALAGILEEFYENLTKPDGEEYSVSTMHTIRASISRYLTLPPQSKPFSIIRDREFKRANEAFYRRIRRLQSPRQPPAFHYATGRTTVWQPQTVNIPCSSNGIMLVQLGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYT0</accession>
    <name>A0AAV4SYT0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_254421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010292">
        <property type="protein sequence ID" value="GIY38341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYT0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="13775" checksum="E1F89F3BDB3EE580" modified="2024-11-27" version="1" fragment="single">MAIHWTLDVAENVAVVKMENVPSKKVRKSVIAIKGYSLEAGICRECSCGENGRCSFENGVKICDCNKGYSLEAGICRECNCGDNGTCFMRNDVKTCACDKDYVFNGEMCKECYCGEKEVFVHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T039</accession>
    <name>A0AAV4T039_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_158128_1</name>
        <name evidence="1" type="ORF">CEXT_202131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010550">
        <property type="protein sequence ID" value="GIY40058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T039"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="174" mass="20558" checksum="2EF89ADE40756825" modified="2024-11-27" version="1">MHYDVATENVRIKHYNADCFELAGLLLTEFSTESRRYFTSDRRYWPLTGHVWNTFVYDCCFRFSRFGHLSYEIFRACRMVVDTGIRAWACSYKYGELKIKAVRKRVEEAMGEAFDIKEFYDIVLCSNGPIMLVEKQVDHYIESSKVRNLPPEEIMLLGTIFWLALPFELKATFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1T7</accession>
    <name>A0AAV4T1T7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_468341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010476">
        <property type="protein sequence ID" value="GIY39532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T1T7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043528696" evidence="1">
        <location>
            <begin position="16"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="294" mass="29131" checksum="0CDD2E7C8674FDDA" modified="2024-11-27" version="1">MKFLILLALAVSASATYTYTLGHHGAYHGLGGYAGYGGYGSSLGYGYGLGGYGGYGGYGLGGYGGYGYGVGGYSYAPSYYHGGAHASIAKYAAAPAISYAAAPAVSYVKPAVSYAAAPAVSYVKPAVSYAAPAVSYVKPAVSYAAPAVSYVKPAISYAAAPAVSYVKPAISYAAAPAVSYVKPAVSYAAAPAVSYVKPAVSYAAPAVSYVKPAISYAAPAVAHVAHAAPVAHVAHAAPIATVAHAAHAVAAPAISYAAAPASRYISAPTAMALTDPTNLTTPTPTATSTRSKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2S4</accession>
    <name>A0AAV4T2S4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exonuclease GOR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">REXO1L1P_2</name>
        <name evidence="6" type="ORF">CEXT_296531</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010683">
        <property type="protein sequence ID" value="GIY40973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2S4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY40973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="188" mass="21919" checksum="67EDF09E97D63D01" modified="2024-11-27" version="1">MTHETVIDTSCVFPHKERPPLKNSLKYLAEIYLQKNIQKGYTGHNSVEDARTCMELMLYKIYTETRTTFVPRPIIPGIIPKTFQSINQSYPKFAVVPFNIVHVMPPPTFICFHVNVSPPFSPFPRLQAIQMKSFYPGEESMAWKSALKRRISYPEFTGADFLLSTMFFFFMCMKLEHDFFLVYENSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T2V1</accession>
    <name>A0AAV4T2V1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_274051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010480">
        <property type="protein sequence ID" value="GIY39566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T2V1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY39566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="126" mass="14757" checksum="3143C5E58F7E6383" modified="2024-11-27" version="1">MHQLVGLSKSGKSPAPPVYHHPAGKKTNDKILRTLIRNQRVLAEEHTSDVLEEHTPTRRLACYIFPHTRLFEPCTTPKFWKKKNVHPRTQPYGSRERYGYSFCKGCMIYLWTSGRVSKEKGEREFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T3U1</accession>
    <name>A0AAV4T3U1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein Jade-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">jade3</name>
        <name evidence="6" type="ORF">CEXT_684111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010705">
        <property type="protein sequence ID" value="GIY41308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T3U1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000030">
        <property type="entry name" value="Protein Jade-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF160">
        <property type="entry name" value="PHD FINGER PROTEIN RHINOCEROS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="255"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY41308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="583" mass="66947" checksum="08DCB9D6124BF9DC" modified="2024-11-27" version="1">MHVMSKCRGAMKPTSAGEKWAHVSCALWIPEVSIGCPEKMEPVVTKISQIPASRWALICTLCRERVGACIQCSVKQCKTAYHVTCAFENGLEMEMKTTAIDSSEEGVKMQSFCNKHSSKDAETEVDEHNARLQKIRSLEAQFHKYVNVKDTVDLHNIDRDVVDFINYYWVLRRRAKFNKPLLITKCDEANLLIKQHENRLYSRLKMFVHLRQDLERVRNLCYMVSKREKIKEEVLKSRVGEQLFEKIYCSDPVEDAKEEKTNKNSLPKPPNPYAKSYINSMHTRSRRRTTSQNMAESGNEHCESENNEMPTLVKCKSEENLSSNDTKNKQETPSFTHSPFVIKIESKKDDKEQNSSVVKQEVETLNEEKNVTEKKDSPERDQSKKPEQLCDLDMSKISSENLTVKTKKLICENETSNDKNSLCLSDKENINALNPIKIKKTRSQTDSRHPELKNNIHELSNPKLELFDDENSLNSTPDLNSPERRNFRLDRRSTRYQMRSRRCSSDVLEHDELPSKSIELVEAQIALSSPIINSHSPSSNNIEKLTLVPEINSRTDESSPSDNSPVLTPKRGRVGLVKLCNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T723</accession>
    <name>A0AAV4T723_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_407311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010648">
        <property type="protein sequence ID" value="GIY40712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T723"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY40712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="148" mass="16944" checksum="941D6E0E2CC8AFC1" modified="2024-11-27" version="1">MFLGPLKIPGNKCAFMNSIRQTPVLHISEFGGQLTDFSDISFPTFDDTSITVCPNENCLKPRPRISVFPQITITGRGDIKKRSTGNVKEKQATLWNNRFTFLQLEEKDMKEVNPTPLSPFYHPVGLKWEKTESSLFLSCFLLFRALWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T889</accession>
    <name>A0AAV4T889_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_160301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010724">
        <property type="protein sequence ID" value="GIY41531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T889"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY41531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9005" checksum="D91D410BA60BB5F0" modified="2024-11-27" version="1">MPDEVGDPLMLQQQNADCNLRPYYPGGTMEVPNSINISTEAVNNNIKAFHNNIEAFNNNIESYNNSTEVFNNNIEAKSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TDF9</accession>
    <name>A0AAV4TDF9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_651341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010793">
        <property type="protein sequence ID" value="GIY42018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TDF9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY42018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12051" checksum="246746AB164EE87C" modified="2024-11-27" version="1">MYEEWHHLWHSSMRANVSENGNFDPFLSASGSQKDGGSSKQENYFCGTGVVIHASGYECQKVESQRAGDAGGPPPFLSPNDFRPREAREDSPCRHDIHHRGMGESIGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TGV3</accession>
    <name>A0AAV4TGV3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL35m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L35, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mRpL35</name>
        <name evidence="9" type="ORF">CEXT_178041</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011329">
        <property type="protein sequence ID" value="GIY45848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TGV3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019338">
        <property type="entry name" value="Ribosomal_bL35m"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15909">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15909:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY45848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="20823" checksum="A1459FBF96AFC108" modified="2024-11-27" version="1">MLKILGTFSSNFVKNCCSTINNVVPQVNKFSTCKLLTPTVFKQLANTNSTYSSQYASMKPLLSVDSQNVNSTRNVTKFSLKTGKKKSVGAVLRRFYRLNNGLWIRRRAGCHKHLWKKTGKDRYNFQQHVVCTKTQCLMLDRMITDHWKKRKYYIDDPFEPYHTRNDFDYVYPYKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJ04</accession>
    <name>A0AAV4TJ04_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">CEXT_776851</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011227">
        <property type="protein sequence ID" value="GIY45046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJ04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="53"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY45046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10413" checksum="0E7C515840544DF4" modified="2024-11-27" version="1">MEETAFIDLLDQHHHLADVCNKADVCKADDDLQMERGPCYRYHCDFGAQCVLKGGSATCDCPTCTEEFEPVCGTDGISYTNNCKLRREACEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TLE0</accession>
    <name>A0AAV4TLE0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_559691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011577">
        <property type="protein sequence ID" value="GIY47423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TLE0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9239" checksum="F385EA6CEF42CAA4" modified="2024-11-27" version="1">MGEARREEKKLLFLRLPLVVRWASLETSLTVLQLAEDNSLLLASSAQLSTGVGSLANVFVCELRRRLCVFSGEFLDSPASVLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TW05</accession>
    <name>A0AAV4TW05_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">TEP1-F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Mug1</name>
        <name evidence="14" type="ORF">CEXT_295581</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Binds covalently through a thioester bond to the pathogen surface resulting in pathogen clearance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer of a TEP1-N chain and an TEP1-C chain non-covalently linked. Forms a complex composed of TEP1-N and TEP1-C heterodimer, LRIM1 and APL1C; the interaction stabilizes TEP1-N and TEP1-C heterodimer, prevents its binding to tissues while circulating in the hemolymph and protects the thioester bond from hydrolysis. Mature TEP1 and to a lesser extent full-length TEP1 interact with SPCLIP1; the interaction is induced by microbial infection.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011869">
        <property type="protein sequence ID" value="GIY49716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1930:FF:000001">
        <property type="entry name" value="CD109 isoform 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047565">
        <property type="entry name" value="Alpha-macroglob_thiol-ester_cl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019742">
        <property type="entry name" value="MacrogloblnA2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041555">
        <property type="entry name" value="MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040839">
        <property type="entry name" value="MG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF171">
        <property type="entry name" value="PREGNANCY ZONE PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17791">
        <property type="entry name" value="MG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17789">
        <property type="entry name" value="MG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01419">
        <property type="entry name" value="Thiol-ester_cl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00477">
        <property type="entry name" value="ALPHA_2_MACROGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alpha-2-macroglobulin bait region" evidence="12">
        <location>
            <begin position="541"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-2-macroglobulin" evidence="13">
        <location>
            <begin position="884"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00057615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00063781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00078071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GIY49716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1338" mass="147631" checksum="F0C00141B56C1C8E" modified="2024-11-27" version="1">MESTARGQLFRQSGSLEHLLETRYWSLSLGENLALSHSREDSGNWLITLSKRSKGVLKLKKIIMDAKNSLGILAFIYIVLATCKAEDETDNGYIFTSPRSIKDGSVNQLQLLRIGCLTEGSVKVKLYCNGGQGENETLTKEQEYMLEDGKKDSFLDFYVEKHLDDSIYDCRIQINGTLCGESISGSDKVYISRPRNHICVIQTDKPLYQPGQEVKFRILKLDKKLKPSNDPDDLVNVYVEDPKGTRLFQFNKINLANGLAQREFPLSDEPNLGTWRITVSTKDDSESTSFEVKEYVLPKYEVSIKFPPYVLANAEKITVEICAKYTYGKPVVGILNLNVSLEKYSYSRDKSPVVQESVKLDGCFNYTINVSSIEPDSVYRYRRIVVIANVIEDGTEVQRNETQYLQRQYMPLNLNFQSDQRQYFKPGLPYTGKLTVTYPDDTPAGCEPIEICCTISKERVIAGWKATKKIKICKNYTSDDSGNIKYVIGALSTDTTSVMIDAKSLKYARDPNSSGSRQDSLNQPTAGVSLRPFYSPSGSFIQLETLDKSIPCGTQKNVRLLFTSKENTDFKIRYEIINQGVVVKTDIQEVSFNTEDDVSSKYENDDDVIKGSEIQIVPPPQSASDSTNDAVSDEENCQSAIEAKYVPPIGEIHIPIDVDASLSPSFVLLVFYVRDDTETIADSQKIQVEKCFQNEVDFEFGDEVKQPGTKTSIQVKSSPNSLCGLKIVDKSVSLLNSNDQLTKEKIFQLIESMDTGIYYSNNPCNEGTPQPGLYSTKSSSMIRPIPGPWSSSSYEDSLSSFKDAGFLVISNLIVFTRPCTNNGGGYGGGPVYQSESFAAFAPGQAVALASTARRPAAPNAVADAKVGAVPMKSAVATRDTFPETWLFKLQETGPDGVFISKETLPHTITEWIGSAVCVNAEDGLGLSNETSIKGFQAFFISYTLPVRAIRGEEFTVVVSIFNFAEAALPVAVNLEESEGFTVTGEPLNAEVCIQPNTNENMKIKLKATTVGKINITVRAETTGSSDVCGSSTVSDAIARDAITQSMVVEAEGFPVEKVQSVLFCPTDEEDQTFTDSFSLSLPDDVVPDSARALVDVTGNVLGPAIENLNSLVTLPTGCGEQNMVKFTPNYLVLDYLTDIGKLTDSIKSNAIRNLNKGYQRELTFRHSDGSFSAFGEVDRQGSMFLTAFVLRSFYEAKRYITIDDNVLNEMQKWIVSRQQADGCFPNVGEIIDKGIQGGLEKEKNTGAITAYVVASLIISKFENETVINNALKCLDNANLTPYETFLFAYSEALAGKLEAAQKRLDDIKPKANSTDGVECVEAPTARRLLTLKQLLTLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U7X9</accession>
    <name>A0AAV4U7X9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_355671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012424">
        <property type="protein sequence ID" value="GIY53871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U7X9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="12131" checksum="051320CDB3CC8506" modified="2024-11-27" version="1">MLCLHQEGKKGREVEGVCSGFLNDGRCNSILESGNEGFGTKIWGGSRKGGGGRGGPNVVKAKKMLGFRFGLEGILMTKLKGRSLKRGMFLIAGIIQVGEGWSLRSGCGRGRISSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UAD5</accession>
    <name>A0AAV4UAD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_661231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012544">
        <property type="protein sequence ID" value="GIY54718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UAD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043394281" evidence="1">
        <location>
            <begin position="21"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY54718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12940" checksum="FE79A00BFF347734" modified="2024-11-27" version="1">MHLHMRILITFILLTLRIYLRRNELIKCNKNFDEENSAPEPNDIMSSWGTRSMDGNIFPLGIEREDGKLFKSSELSLLSRMMLPRYGRSFRKSFVGEKLLLKDCFHFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UJT7</accession>
    <name>A0AAV4UJT7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_337901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013005">
        <property type="protein sequence ID" value="GIY58038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UJT7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12614" checksum="6E68C6D6832562E1" modified="2024-11-27" version="1">MILALAKGNYCSGRNVFVVLFEQEQLSVVSILDWEQNRPSKFYILMFCEQRHMQCTKTHLRVDITMDLKMELTQRIFTGEEFYDATTLTERKRAVGVNAVMAVPNSMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UKG2</accession>
    <name>A0AAV4UKG2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_691431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013047">
        <property type="protein sequence ID" value="GIY58337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UKG2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY58337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="115" mass="13538" checksum="AEC7F02DB121F6AC" modified="2024-11-27" version="1">MARINGSWIMNSLALPKSSERFEKLIKWTSGQTINTSNQKTKKSVRNVKKNVVVLRKTYKRFILRVKKLVTPKMILGSQTLKKLDDLIVHVIDILQTELSVLYRKYPKRQWILKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULK4</accession>
    <name>A0AAV4ULK4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_464811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013092">
        <property type="protein sequence ID" value="GIY58712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10087" checksum="BF38899AF3949711" modified="2024-11-27" version="1">MSAAAGVPHHDAQAPVHRPAAQRPHVHHLQELHHPGAARPALGQIQHGPRGEWVLTYSGKMLGDILVCCGMCTQVLPNSPMRESLQLMVHTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULZ5</accession>
    <name>A0AAV4ULZ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_37011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013105">
        <property type="protein sequence ID" value="GIY58793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULZ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY58793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="100" mass="11715" checksum="A2CDA93688815D56" modified="2024-11-27" version="1">MTFRIDAFSSNSSSLLETDRTQKQGRKKSPIFLLAEETTQTKDETNLRHTAAAKQARKIIDAKNKRKVKRMSEVHNRWPDERKRIFPPSRIGMRECDIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UV76</accession>
    <name>A0AAV4UV76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_39331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013499">
        <property type="protein sequence ID" value="GIY61674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UV76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY61674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="12817" checksum="B88BEEB16030DDAA" modified="2024-11-27" version="1">MNPQNQPTGLLHAAIHFHRCSESNNTKIIKAHRTIKREGGMQPPSVHVDDALSCESVTGRGPRQRPFLHSSPDPSSVGQSGGCLKGGLKAEREESCAVSFTTSAITRQGRQLAEFAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UZ28</accession>
    <name>A0AAV4UZ28_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_334821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013722">
        <property type="protein sequence ID" value="GIY63247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UZ28"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9940" checksum="2A563AFA883E34E5" modified="2024-11-27" version="1">MGMKINTFCVGMSFLEGRPVVGEISNNYSILNLDPLPKWLGDCHLWFGQWVLCFLYCQHWVLRMCKEWVLKRAELTEKLVLGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V1E3</accession>
    <name>A0AAV4V1E3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_325491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013771">
        <property type="protein sequence ID" value="GIY63663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V1E3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY63663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9960" checksum="54BA7656DA4FF469" modified="2024-11-27" version="1">MGQMDEKIREKQLFFSGKRDKREIMGRGSRNDIFSRNRDEKLLFQYSADASSLMQMARHQKDVKYPFMSTEKDVLEAGKECQMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V423</accession>
    <name>A0AAV4V423_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_509551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013917">
        <property type="protein sequence ID" value="GIY64734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V423"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY64734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10610" checksum="B1606A7B71EB16B1" modified="2024-11-27" version="1">MGLCIGSKPCHHVGGCRPVIWICRRKMGSNNNTLATERKLASKKCQNTHPAQEPRQKKERTHYGHRIYYFQRDSWYKLPDTEEKRLNTPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V5Y7</accession>
    <name>A0AAV4V5Y7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_612551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013983">
        <property type="protein sequence ID" value="GIY65354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V5Y7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY65354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="55" mass="5915" checksum="B77FBCEEC1038744" modified="2024-11-27" version="1" fragment="single">MSKKLDLTQADIKILETQLAVAHDWNGTAKDVAQGDVPDATVPDGHADSTKKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VFJ0</accession>
    <name>A0AAV4VFJ0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_130731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014493">
        <property type="protein sequence ID" value="GIY69126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VFJ0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY69126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="131" mass="15240" checksum="64F243C5DC7CD0A2" modified="2024-11-27" version="1">MKTRVPKNNNKKITEKRKNSRAHEFSRKSLKRGIKLIREKTLCSLEEPENSETARRYLSLPSPVCHFRARVTQAWVMSRHSAVHLLAKGFDISINKSITETISFRKSKSITTLNSLSLSKRHEAFLWDNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VIR6</accession>
    <name>A0AAV4VIR6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_244541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014639">
        <property type="protein sequence ID" value="GIY70237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VIR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY70237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15407" checksum="BE1ED279A3362C13" modified="2024-11-27" version="1">MIVLELLKRVVKSLPARSPLESQRIESKPLENVVRIDYTKVNKMFYCCHLDLNLIFVHKARKTSPPKKKKNWRGQKHPLVKGMPDGEGLSIIRLHAVPVWDIAANTNRHKYTLMHQEFGNSRRSLHRTHIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VR83</accession>
    <name>A0AAV4VR83_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_814941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015006">
        <property type="protein sequence ID" value="GIY72895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VR83"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY72895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10854" checksum="680EC030B2D81CF7" modified="2024-11-27" version="1">MPQTLFKTPRKPSTSAMHSIIRGWINRRGGTKLPTAPPLHALSKKIKRKWRSGKLVGQENIEWPSEQEASKIDFTFKEDDSILKLDWELQRFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W4L3</accession>
    <name>A0AAV4W4L3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_427061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015566">
        <property type="protein sequence ID" value="GIY77000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W4L3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY77000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="264" mass="30657" checksum="66DACA24552EFDCC" modified="2024-11-27" version="1">MLKVVEELKLTTICLNIYLNHLKICLKHLELRGNDFGSSLEDLFNISFKPSYQKQDPNLEDNWRGRIRSDIKPDAWAERKNDISDRKCLENNTFHEALTGAAALWRRHGGKDIRRNPKEFSDSAVNGIDFTAENNLNSEPDDESEDWNADFNFKSPEILTEANVQDTLETGEVEYWDDDAQSYSKSSPAYSPTKDIDPVEESDWETSSEEQFPNNFQRVYRHPRTKESSHDNMQFTPSDFHVQRISRPEVWCPLEEGQFDDAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5I3</accession>
    <name>A0AAV4W5I3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_566111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015713">
        <property type="protein sequence ID" value="GIY78070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5I3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY78070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14070" checksum="ED64D4B661DE117A" modified="2024-11-27" version="1">MILEEENDDVGVLNVSMPPKRIGSSPQHVFRNSSLPFTHKKQESSIESHACRRRDESFYTNQIEDEFQNLSCSEKYQGDTNDSDDFNWAAYLGRECGESSSRTMDGAIPQGSNLEDERLSSEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WER6</accession>
    <name>A0AAV4WER6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_253581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016110">
        <property type="protein sequence ID" value="GIY81351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WER6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY81351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13674" checksum="BB988A3BA292BC53" modified="2024-11-27" version="1">MPRIRWFRNARRCSRTTSRGACQPLGTEHGVVSWKLKNEPFHFTIRMVSLMCLLVVDGWCLQRVRRPANWALTLGGKILSHQPGCHMPSTAGDRSWVERNICLIAHEHRHQIPVPATGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPS1</accession>
    <name>A0AAV4WPS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_671721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016396">
        <property type="protein sequence ID" value="GIY83538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY83538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="16910" checksum="B18B483A9732B727" modified="2024-11-27" version="1">MAINQMQLDCNSRRNRVAVELSRIFHKEDVRVKLAGEQLKIFPVNSDVHRAVTRYLTEKKLEFFVITPKNQRPLKAVLKGLPVSYSTAEIEEGLSELGLKLDQSTGLEEEDVTGNGLNITLLEVVVKQHGSSVASPDISSLMLKVCPFITSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WRI2</accession>
    <name>A0AAV4WRI2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_109451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016615">
        <property type="protein sequence ID" value="GIY85106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WRI2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY85106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="10424" checksum="CB459EFF1904C99A" modified="2024-11-27" version="1">MRVGVGLMRNFPSTNRATVAVGRPRGRRSFQDYDVCDTICRCPLPIPLRTSCHPEDARTMEKRAHMSRSHSDVRFQWISSHSTQYRNCDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WVA7</accession>
    <name>A0AAV4WVA7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_649061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016853">
        <property type="protein sequence ID" value="GIY86860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WVA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9371" checksum="7F0AB7D6449B62FC" modified="2024-11-27" version="1">MEKGPSTMMSIKWEKDILLYDDQMGKGLATMIARTWLALFSDHSSAAPFPDPDNRSDRLGPAQGTVMSHSRERQPTLHGAPPMGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XCN3</accession>
    <name>A0AAV4XCN3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative alpha-L-fucosidase</fullName>
            <ecNumber evidence="3">3.2.1.51</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alpha-L-fucoside fucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Fuca1</name>
        <name evidence="12" type="ORF">CEXT_602531</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="3"/>
    <dbReference type="EMBL" id="BPLR01017591">
        <property type="protein sequence ID" value="GIY92847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XCN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000027">
        <property type="entry name" value="Alpha-L-fucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016286">
        <property type="entry name" value="FUC_metazoa-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057739">
        <property type="entry name" value="Glyco_hydro_29_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030:SF37">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00741">
        <property type="entry name" value="GLHYDRLASE29"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043618683" description="Putative alpha-L-fucosidase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 29 N-terminal" evidence="11">
        <location>
            <begin position="19"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY92847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="310" mass="36405" checksum="60AA9CCD0F8AE07E" modified="2024-11-27" version="1">MKKFFTLLLTVFLISLVGGKYTPDWKSLDARPLPGWFDDAKIGIFLHWGVFSVPGFGSEWFWSYWAGKSKDYVNFMNKNFKPGFSYPEFGPQFTAEFYEPEKWADIFEASGAKYVVLTSKHHEGYTLWPSKVSWNWNSKDIGSKRDLLGDLAKAIRNKTELHFGVYHSMFEWFHPLYLLDKKNGYKTQYFVDSKALPELFELVKIYEPEVIWSDGDWEAPDTYWKSKEFLAWLYNESPVKDVIVVNDRWGANIPCHHGGYYTCSDRYNPKTLQAHKWENAMTLDKGSWGFRRNVDLSGFFDTRRTRHDAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGJ8</accession>
    <name>A0AAV4XGJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_359011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017639">
        <property type="protein sequence ID" value="GIY93194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9197" checksum="EC5A904AD94A199B" modified="2024-11-27" version="1">MTQLQPIVKLFPGDSSPISTFRKMCHKESVCQIIREKHFPSNTAKILVSMSSSCANTAWTIVTWLTLHSNWLNPHIWENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHL1</accession>
    <name>A0AAV4XHL1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cilia-and flagella-associated protein 58</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CFAP58</name>
        <name evidence="1" type="ORF">CEXT_105651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017747">
        <property type="protein sequence ID" value="GIY94127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHL1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="127" mass="15375" checksum="BD983E3FBE9663FF" modified="2024-11-27" version="1">MPKQELQRERYKNSALETAMQQPLNVHRWRLLKGTDPEKYELLESYQTAQKKLLKKKKYVEKANYSQLLKEKNDKIKTLSFEINMNETYMSSYQTEISHLKEEIRKMKLKQFFREKKEDSSIFGKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XHZ7</accession>
    <name>A0AAV4XHZ7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_78411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017802">
        <property type="protein sequence ID" value="GIY94571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XHZ7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY94571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10288" checksum="56BC3311E14607B9" modified="2024-11-27" version="1">MLNEMAGYRATNNCREISGFATGSAVRKVWLMDRYEQMVFLIVPYIKDFQPVLCRARPEIAIDVAIVSIYRTLDHSGFATNLSYHCPMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XQ32</accession>
    <name>A0AAV4XQ32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_159061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018093">
        <property type="protein sequence ID" value="GIY96834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XQ32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13838" checksum="6D4F9A0973CA0300" modified="2024-11-27" version="1">MYKKFKITESFNVYQKIIIKESLDTYIKRSESLDTYIKRSESLDRVGYLRASDSPLLLEEVRPSKWRSTERNGNGHSGVNRADPQLPQPALDSSELKMGIYPKCMVTVLVTTLCPHTMAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XSI4</accession>
    <name>A0AAV4XSI4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_386011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018240">
        <property type="protein sequence ID" value="GIY97992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XSI4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="105" mass="12121" checksum="FD434C8FB0D5B5D8" modified="2024-11-27" version="1">MGTYSKFPWRASQPLLPSAYCFPCPCFMYEHPRVVGNHLRRFAFLWHDRNRLRLSHSASTATSRRGAQSIKYGKVTGHGAWPFFFPSLSGHFNERSLAEKIFAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XUE2</accession>
    <name>A0AAV4XUE2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_800561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018231">
        <property type="protein sequence ID" value="GIY97943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XUE2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="143" mass="15989" checksum="7B412B05F8BD89A3" modified="2024-11-27" version="1">MSNPAHSIAPMCQPSGGSVYVRNPAPLVVKSNVPSFRLSMSGNQFLKFEAQFSIHQAAPTYQEPSSFSCETQCAIHQCAPTSKSSFYSFETMCLPSSCSDYIRNPAPLVLKPNVSSIRLHRLRWLTVIIIKNYDQYLPLFIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XWU0</accession>
    <name>A0AAV4XWU0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_357901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018283">
        <property type="protein sequence ID" value="GIY98370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XWU0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="137" mass="15816" checksum="6F444DDE2E7E23E6" modified="2024-11-27" version="1">MIKHSRHNEASAFANTLILPSSKWLCVLQRRNSNYPRKAEEVPYQTETEALVFKTSLQLPHYRRSAVTSIRGNCLLNLLTIFPITAAEFRRKGGGWWKEKKFRFQIRAAIHPPFLNGFPSLQRNRFLCCTTVLIAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XYZ3</accession>
    <name>A0AAV4XYZ3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Svep1</name>
        <name evidence="6" type="ORF">CEXT_602081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018383">
        <property type="protein sequence ID" value="GIY99094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XYZ3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090036">
        <property type="term" value="P:regulation of protein kinase C signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060074">
        <property type="term" value="P:synapse maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051277">
        <property type="entry name" value="SEZ6_CSMD_C4BPB_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45656">
        <property type="entry name" value="PROTEIN CBR-CLEC-78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45656:SF2">
        <property type="entry name" value="SEIZURE 6-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00084">
        <property type="entry name" value="Sushi"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00032">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="Sushi" evidence="5">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="5">
        <location>
            <begin position="73"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="5">
        <location>
            <begin position="152"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="5">
        <location>
            <begin position="232"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY99094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="358" mass="39320" checksum="5B0AD5E8D10E8BFE" modified="2024-11-27" version="1">MDVNGVIEDHPLLDARRRGQTFPSGTELRFGCREGYEVVGPSILYCYRHGEWSSASPTCRPIPTTTATPQLKVACNAISQSGPNGEIEDVPLIDPRRRGGQGFVVGSTVTFTCNENYVMVGSNSITCLRTGRWSSAAPRCDAVSRTSTNNRITCSNPSVDPNGEIEDIPLIDPRRRGQGFEVGSTVTFSCKEDYELVGSNSITCLRTGRWSNVSPRCDAISKSFQSDPSNVISCENPGPISNGRVIVFRTLDGNRPPPAVEDDFEYPVRTRLQYSYEEGLPPARESNLICEATGFWSAEIPMCIEERASSFTNEVGIFCLQMIDNLLHPSTNWGRKSRDQISGHVPSTELKDPPVGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XZ72</accession>
    <name>A0AAV4XZ72_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_165501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001033">
        <property type="protein sequence ID" value="GIY99329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XZ72"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY99329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10472" checksum="EFDAA17850367EED" modified="2024-11-27" version="1">MTPIQNELKQIKLISDDIGGGGLRPGICPSSLPHRTKDAECLRATCAIHFTLFSLPWQQKVPLGNWEGKKSHGIFFFPSCTHSGELLKSIHTSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y055</accession>
    <name>A0AAV4Y055_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_737911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018472">
        <property type="protein sequence ID" value="GIY99908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y055"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY99908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="171" mass="19511" checksum="308883B647C3CC1C" modified="2024-11-27" version="1">MIRIMKGTPNLWKRPIMLTSTPSLGFRNRMALMSDGGWGGGGAGRHLSSILREVSSSPSIIGHIPNGSRVTRQKHTEEEEEDERLSRLCKVSGTFTDSSPRHVEKLFFFLFGFCWDLCGPTFVFVKKESLMPRFLFIVYFELHAFMDEAGTKRKFGLRKTSMNRLGFIVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3M1</accession>
    <name>A0AAV4Y3M1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_485451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001237">
        <property type="protein sequence ID" value="GIZ01016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3M1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ01016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="108" mass="12365" checksum="B3D6B13FC9059A30" modified="2024-11-27" version="1">MATPYSNQRSLISSFSKNMLWKMAIIHSGLFVSLSIFRTDCQPERGIQHPKVFSCQSCFLDLRGLILITNSSANTFKSEDFKDVSKNAEDNISRLYKVIEKRGSYITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3N0</accession>
    <name>A0AAV4Y3N0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_396391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001347">
        <property type="protein sequence ID" value="GIZ01758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3N0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="9856" checksum="F80DDCA7A3B6DC63" modified="2024-11-27" version="1">MNQQQETPEFLVRATNRALSITKSEVLSRTHHQPTTQCVQQNGRKESHLQESFLSILTARHPLQREGRCQGNVLCPSPPSFVRDTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y3T7</accession>
    <name>A0AAV4Y3T7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_43931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001256">
        <property type="protein sequence ID" value="GIZ01115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y3T7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043685888" evidence="1">
        <location>
            <begin position="19"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ01115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13940" checksum="827C6DCBD7364E79" modified="2024-11-27" version="1">MKIPKELFFKVLFTLLWTDNTVIKAYERVVKVSNQMVIMNSCPIPLEDFERSFSSSRNCPRIQEIDGNEASFHMILKVCKNCILKDVSEMCFYDPRLFPGSIFNLSTSTRLFESTERQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y7R8</accession>
    <name>A0AAV4Y7R8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RuvB-like helicase</fullName>
            <ecNumber evidence="10">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RUVBL1</name>
        <name evidence="12" type="ORF">CEXT_176691</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 10">Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="10"/>
    <dbReference type="EMBL" id="BPLR01001420">
        <property type="protein sequence ID" value="GIZ02245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y7R8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060828">
        <property type="term" value="P:regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042127">
        <property type="term" value="P:regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="62"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIZ02245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="456" mass="49893" checksum="58D70751245EC332" modified="2024-11-27" version="1">MKIEEVRSTTKAQRVAAHSHIKGLGLEENGYALDSAAGLVGQKQAREAAGVIVDLINSKKMAGRALLLAGPPGTGKTAIALATAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRVKEVKEIYEGEVTEITPVESENPMGGYGKTTTHVAVGLKTAKGLKKLKLDPTIFESIQKEKVTVGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIVQDVTLHDLDVANAKPQGGQDILSIMSMLIKPKKTEITDKLRKEINKVVNKYIDQGIAELVPGVLFIDEVHMLDIECFTYLHRALESSIAPIVIFATNRGKCPIRGAEDVSAPHGVPVDLLDRLMIIRTLPYTSEQMIQILKIRATVEGLNVDEESLLALGEIGTTTTLRYAVQLLTPASLLAKAGGRTTIQKEDIEESRSLFMDAKSSAKMLLEQKDKYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAW2</accession>
    <name>A0AAV4YAW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_163161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018932">
        <property type="protein sequence ID" value="GIZ03307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIZ03307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9244" checksum="C816BEB30434B23D" modified="2024-11-27" version="1">MHGHKCGDSTQNRTPDTAGTVNKPLSPSLDLRFLFFYSSAFEKLLRSDKHRPHFPILAYAAYVGFTFWAQSYYGTPQFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBA7</accession>
    <name>A0AAV4YBA7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">CEXT_692061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001631">
        <property type="protein sequence ID" value="GIZ03635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBA7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000054">
        <property type="entry name" value="Slit guidance ligand 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00010">
        <property type="entry name" value="EGFBLOOD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="3"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIZ03635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9785" checksum="649515B685604A78" modified="2024-11-27" version="1" fragment="single">GEPEDICISKPCKNGGTCEKKRGRNYKCHCVEGYSGNNCGDITWCKDNDKNICGDNVTCKYDQVIRSGYCFCEKDFYFDAKNKKCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M8S8</accession>
    <name>A0AAV4M8S8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_648781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019508">
        <property type="protein sequence ID" value="GIX68635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M8S8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="12909" checksum="C041B599A35AD05A" modified="2024-11-27" version="1">MSVGHHPLLFQRSPRFYIQSTFPDLLLNMTVHQIRHESLVLCQVISIFCLQVLDLIIDDGAILLFSGWGFPGDLRERELTALPRTLGRGTRHCREGRERREECDVCSGRTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBL9</accession>
    <name>A0AAV4MBL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_170381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019471">
        <property type="protein sequence ID" value="GIX68219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX68219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="101" mass="11348" checksum="7325225E88BACA87" modified="2024-11-27" version="1">MPQFKIIQNLEGFGCNLILRDLFVKPESSRSCHSSFRAHSEPTFLACRFSLVYSGLAHPRCLNWAKFSGRPTPLGIGDDTFLGIPALELVSFQSPDMNEWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDJ4</accession>
    <name>A0AAV4MDJ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_744851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002056">
        <property type="protein sequence ID" value="GIX69476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDJ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX69476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="38" mass="4282" checksum="7D260DB194F24977" modified="2024-11-27" version="1" fragment="single">PQSQVPPRLTHVARRVCESRRAVFIPCVAQGHPAPTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MHT8</accession>
    <name>A0AAV4MHT8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anoctamin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ANO1</name>
        <name evidence="8" type="ORF">CEXT_734231</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the anoctamin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002259">
        <property type="protein sequence ID" value="GIX71860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MHT8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF83">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="7">
        <location>
            <begin position="49"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU280814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX71860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="331" mass="38218" checksum="61F3BE71BDF3883E" modified="2024-11-27" version="1">MCPDPTTPPTQVPGHVEISENELADHCQSSIGVFNPVLDFTGRHHYSSKRWQIKKHGKSSSSRWEEDYALAEWGATHLFFEYLEMILQFGFVTIFVAAFPLAPLFALLNNILEIRLDAHKLVCSYRRPVGVRVQNIGIWYRILDSIGKLSVLTNGIIIAFTSDMIPRIVFRLAWSEDFTLHGFVNYSLSHFNTSDFPRDSQPQPLILPGSQDPMNVTICRYRDHRNAPWEEDKYSFSDEYWLLLAIRFAFVLIFENLILMLTTLLRWLIPDVPKKLMERIRHENFITNEIMIAQELRRAKGLAAIPEERELGDHNTAKANGDTPNIKQTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MJP9</accession>
    <name>A0AAV4MJP9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 8 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Vps8</name>
        <name evidence="2" type="ORF">CEXT_466521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019857">
        <property type="protein sequence ID" value="GIX72535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MJP9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="164"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX72535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="481" mass="53767" checksum="81E89144DC45867D" modified="2024-11-27" version="1" fragment="single">MAEDFNTPTISRREISPSTLGDLNFDIEELDAKEFNLPVIDTPPTLESILNEQDDVSLSDEEFSSNVGYFQETCETTSIDSNESHSRRERGKRKVLFSKTWIYSTACNTPWSFSTASICCGTCQCWKPTSMAVSSVVAIGTFHGVVLIFDPQQVLKWCLGTTEYGEKYGSVSAIAFNTDCSRLLAGYSRGEITMWDLHKGKLIRTIGDAHPMQNAVLHIKFSDDPTLALCSDSGGSVFELNFKRVMGTRTCETRCIFSGSRGEVCALEPLRMTPHFRSHPSQEVCLVALGTVTKVIAVTIRPSLRVWFTHALRADPDTLPVLSWQFVVIQVSSTTRIIDPVLAFGRQNTIYFFSSIFIHLLEYVFQNCAVNFASAEKINFIPLQKIELQYAFQNFAWLNSRTLVTLDVLEQLHVIDVKSDEELEILDLADVQLVYGTSHFKGLATGGNVSKAMAAAGKSMLLFYGCLWKSVITFKEQQYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N0X1</accession>
    <name>A0AAV4N0X1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_340581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002759">
        <property type="protein sequence ID" value="GIX77495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N0X1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX77495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11662" checksum="AA67235A50BBD76B" modified="2024-11-27" version="1">MTNPVVTANNYDQLSGDETDAANVVMTVAPEPRLPPIMVRFNDGLKEHVAAISNQHKEDVRVKLAGEQLKIFPVNSDVHRAVTRYLTEKSWNFLLLHRKINAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2A7</accession>
    <name>A0AAV4N2A7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DBH-like monooxygenase protein 1 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">moxd1</name>
        <name evidence="6" type="ORF">CEXT_194101</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002872">
        <property type="protein sequence ID" value="GIX78853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2A7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042420">
        <property type="term" value="P:dopamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.230:FF:000001">
        <property type="entry name" value="Monooxygenase, DBH-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Copper type II ascorbate-dependent monooxygenase C-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX78853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="252" mass="28816" checksum="71C16641B9868C77" modified="2024-11-27" version="1">MIRPVAIPPEGIRIFAVFLHSHLLGRQMKLRHFRNNIELPFIASDQKYDFNYQDYRYLPQEVIVKPGDHLTVECTYDSTGRNMTTFGGLGTLQEMCLAFVLYYPRISRARSLSSATCDLVKSLAGLDTRNSNADDDDSNLTFYQHFHTNNPWDTYYAGIAEAAMRFGYHSTQCYLGDGRRVQISGLITYPRNIRPFIEPARCTYIEPSRSQEQWKDNFLYTTYTGAATAVTSAYPVTVLAFCILLQFATIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N2C9</accession>
    <name>A0AAV4N2C9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_313641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020372">
        <property type="protein sequence ID" value="GIX78005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N2C9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX78005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="14498" checksum="6A14ADE55EDF4DF4" modified="2024-11-27" version="1">MTNVVHANVCVTKAGKFMGILLIYGQSIPELQGKKTINTGNELRKSMGCGNYETSKAWAKFVLFPMVHRWTEGPLITSHKYSKRCLKQCFKTTNTYSQILEGSSIFDNQSQTECSYFRSPETKLNKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N512</accession>
    <name>A0AAV4N512_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ycf15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_520131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002930">
        <property type="protein sequence ID" value="GIX79365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N512"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX79365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11366" checksum="B2517F19ADB787B4" modified="2024-11-27" version="1">MIVSRKGCSILCRGSSLPGRDYYQSSPFRESPERPDRRFNENLKECQMIASRKGCSIFVQGVHLFQDVTIISPPHSGGSPERPGRHFNEVPNYLKMEIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N8E2</accession>
    <name>A0AAV4N8E2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_528711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003080">
        <property type="protein sequence ID" value="GIX80987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N8E2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX80987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="12066" checksum="6B95437F322A856D" modified="2024-11-27" version="1">MAPQEIGNPSMSPKTITKQQQPINQPKFRSKGLPSVLCQGRQPIPHRKHTAVRPGVTRLHPWTWVAYKTLTFAAHRRVGNPTGDRHAQFDAGSVWCCLLGVCAASGGGSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NAA2</accession>
    <name>A0AAV4NAA2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription factor elt-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">elt-1</name>
        <name evidence="1" type="ORF">CEXT_372841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003161">
        <property type="protein sequence ID" value="GIX81742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NAA2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18303" checksum="2870E6EC716FA88C" modified="2024-11-27" version="1">MGKRGKEKERSSSKQTGSENQWGFDWAEQAFVPCRYWTIVDYEMLTMSKDGKIRSKEDALASIGRKMRRPIAMKKDGIQTRNRKIVSRGRKKCSASMEDGGRTYSSRDYVDCNPIPQCPRAPYVDNETFFPPECSGGPFNNLQHSGYVLHTYPQAVMGAMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NB36</accession>
    <name>A0AAV4NB36_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_741951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020686">
        <property type="protein sequence ID" value="GIX81525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NB36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="15463" checksum="00AEB529741FCB6E" modified="2024-11-27" version="1">MLVGDLIHYFKDTCCLPDLVPTVQYCSRSHSFNEKHVKFFNRRSLIYYTSRRSYAMWYPNSYRNIHVHKAILSARPLCVQAYAHQRHEGTYENALKPRCGCRYHAPNASVRTPTPLEELKWESASMLAQPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE23</accession>
    <name>A0AAV4NE23_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_55641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020694">
        <property type="protein sequence ID" value="GIX81642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE23"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX81642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="89" mass="9725" checksum="E8F7F2A61FD5CED5" modified="2024-11-27" version="1">MMLTVTNGEMELTATKGEIELTATKVEMKLTATKVEMKLTATKVEMKLTATKVEMKLTATKVEMKLTATKVEMQLTATKGEIELIASKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NK49</accession>
    <name>A0AAV4NK49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Laminin subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">LanA</name>
        <name evidence="16" type="ORF">CEXT_254861</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
            <location evidence="1">Basement membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003410">
        <property type="protein sequence ID" value="GIX84198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NK49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030155">
        <property type="term" value="P:regulation of cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030334">
        <property type="term" value="P:regulation of cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045995">
        <property type="term" value="P:regulation of embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009888">
        <property type="term" value="P:tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00055">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000074">
        <property type="entry name" value="Laminin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000454">
        <property type="entry name" value="Laminin subunit alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000065">
        <property type="entry name" value="Laminin subunit beta 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050440">
        <property type="entry name" value="Laminin/Netrin_ECM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009254">
        <property type="entry name" value="Laminin_aI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000034">
        <property type="entry name" value="Laminin_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056863">
        <property type="entry name" value="LMN_ATRN_NET-like_EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574:SF406">
        <property type="entry name" value="LAMININ SUBUNIT ALPHA 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10574">
        <property type="entry name" value="NETRIN/LAMININ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24973">
        <property type="entry name" value="EGF_LMN_ATRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00052">
        <property type="entry name" value="Laminin_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06008">
        <property type="entry name" value="Laminin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00281">
        <property type="entry name" value="LamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51115">
        <property type="entry name" value="LAMININ_IVA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0084">Basement membrane</keyword>
    <keyword evidence="7" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 12" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Laminin IV type A" evidence="15">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="14">
        <location>
            <begin position="159"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="14">
        <location>
            <begin position="366"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="654"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="732"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GIX84198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1040" mass="114973" checksum="8635E9A9F35C0F78" modified="2024-11-27" version="1" fragment="single">LSSYGSFIRYTYFTSVDKTSPIESSVILILFLIGNNITIVHDHIEQPADGIPFSVEVSLIEHEFHHISGRGNSRADDDGFGEFEAVLIRGSYFQPVQEIKLSRVLMDTANDNYIADAPQALRVEQCHCPPSYMGRSCEECAPGYYRSKTGPYLGYCVACQCNGHAQTCDVNTGKCIGCQHNTVGDHCEKCEAGYHGDSTQGTPYDCLICACPLPITSNNFAESCEVSPSGKEISCVCKPGYYGPRCEAWPRLLRFARSSRQHLPALPVQRQHRPQQARQLRFSDRRMHSVSEQHIRASLRAVCSRILWRCHWRQGLQNAIVINAELNGVIMILANVFVGPTLKEHCAIDVRVNHWGFQSCGGCRSCNCGRASTSEQCDLETGQCSCQPGAGGLTCDLCEPGYWNYSPNGCVSCNCDEKYSAGAVCNAVTGQCQCLPGVLGDKCDSCPYRWVFVKNEGCLECDVCVHGLLDATDALEHLISPVTEEMKDVSSSYFANKRLQNVNSTADTLRLGVDELLLDPTGLDYSPLVSSIQDIEKKRDAIDRTANHLHFQAETVDTDADTTRINALEVEKLIRDTIDKVNEIIEELGKLSEGIQGSLGPDIDNLIQQAEYILEDLRNRDFDPAQNDTVDEYTACEELLDHVKSFELPVLESKMKFEEENEKLKNLIAMLEDLKNNSQRAYAVADDAQTLQEELQGIPIEEIIALVEENGDKVYDILKNGTDLLEKAKAFIQDARKSYGNLNEDAERLMLAIRDLKDNIQDTEESFNDLTDPIREATEHAAFLMDQAMLLDQSLANTRNSSEAAVKAAKAYANIEEAINDAYEAAEAALKAADLAGSMSDGILDKTRDSKDTTAQLLESAYQLEDQVTALEPQLQLAKDGVLLIGYQNGKTTKGLEHIRKDLDKLPLHSLGALAELAANDSAAADQVAQRARERIEDMVSKLPDDEIRAKEVPKAIEDSKQAIKAAHSYADRVASIVPDTNALIDKASKKESAMRIIGTDVSDKIAKLQQKVAIARTQANRIKTRRAVLREHYPPSTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTW0</accession>
    <name>A0AAV4NTW0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_321381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003659">
        <property type="protein sequence ID" value="GIX87170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTW0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX87170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10066" checksum="A4F75F463AE2A977" modified="2024-11-27" version="1">MRFLKQNIKQAVTNLHFLKQNIKQAVTNLRSLKQNIRKAIINLQFLEVEPKVVTNLQFLEAEHKTYCYKPAFLEAEQTGCYKSTIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NU40</accession>
    <name>A0AAV4NU40_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Vesicle transport through interaction with t-SNAREs homolog 1A</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Vesicle transport v-SNARE protein Vti1-like 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Vti1-rp2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">VTI1A</name>
        <name evidence="18" type="ORF">CEXT_325562</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="11">Interacts with distinct SNARE complexes that contain either STX5 or STX6. Interacts with NAPA and, to a lesser extent, with NAPG. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021313">
        <property type="protein sequence ID" value="GIX88372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NU40"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15891">
        <property type="entry name" value="SNARE_Vti1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000078">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREs 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.400:FF:000001">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREs homolog 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="17">
        <location>
            <begin position="118"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="5"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00065755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00071612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00081711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00082368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="GIX88372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="219" mass="25172" checksum="D4C778F81B3704CC" modified="2024-11-27" version="1">MASLMESFEQQYAALSAEITSKTSRLNNLSGIERKMLISQVDRQMEEAHELLEQMDLEVKGMPPASRQKYQIRLKSYVAELSLLDKELQKARISPRDENSLRDELFDGDYVKDDQKQRLLDNTERLESSSRQLEGGYKLAVEAEQIGSQILTDLSSQRETIKKSKSRVQETNYDLGRSSRIINGMIRGIKQQKMILYAVASLMFLTIVLAIYFTVRKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NXC5</accession>
    <name>A0AAV4NXC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_463131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003814">
        <property type="protein sequence ID" value="GIX89003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NXC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9362" checksum="2E280DF253830090" modified="2024-11-27" version="1">MNGSLNTPITVTQEWLGSIQIYGLTGEHEVRKTSFNFVSCSLSYEMHSIICKIQIPGICKWPLLCCNHSSRQPPHYILNLGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2K9</accession>
    <name>A0AAV4P2K9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_35631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003914">
        <property type="protein sequence ID" value="GIX90134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2K9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="217" mass="23536" checksum="987C01AD918EB887" modified="2024-11-27" version="1">MIEIILRFQVVGGQAIIRVPTTHSSPLSSKNSDSSCTVLSSPRGAKWYEGVNRILIPNALKGGRRVKNGGDIVSREQGGEFLCGGRSGVGGFSGNVPVYGSPVWRKWRFSLGFMLSKTVVIKAFANNAHDKSISVIVMKFYTVLSTFTDTAVFICKGGRQLFVFQSTPPTHHPLSSKNSDSSCTVLSSPREAKWYREAGGVKRILIPNVLKGEGVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P4D2</accession>
    <name>A0AAV4P4D2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_609191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004020">
        <property type="protein sequence ID" value="GIX91388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P4D2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13316" checksum="8F9EAAE23AAA674E" modified="2024-11-27" version="1">MEILPTPLAEIVHKNSSQVFASDNLEQEKRKETTRRGKHGTQWDAMEFHYSVAGNKDVAHKMNLNEERPRPFFIGETAKQAFIKKMTFEGREKGESTTKLRFKEKNLLESIHFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P5C7</accession>
    <name>A0AAV4P5C7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_216841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021496">
        <property type="protein sequence ID" value="GIX90357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P5C7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX90357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="27" mass="3112" checksum="FF1D499805406962" modified="2024-11-27" version="1" fragment="single">MRGFPDYPGANVMFEMLQVIVAEDAFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P9C0</accession>
    <name>A0AAV4P9C0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_757801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021610">
        <property type="protein sequence ID" value="GIX91707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P9C0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX91707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="9072" checksum="580D9AC25D145338" modified="2024-11-27" version="1">MVGIKKNNKCCKGFHEAAEEPSAMSTQMSDGEREKAAKGVGEHVSFAIPDPACRLREGGGPSKGWAVDEGIQVCLIDSESGGYKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAB7</accession>
    <name>A0AAV4PAB7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_532891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004355">
        <property type="protein sequence ID" value="GIX94292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAB7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="92" mass="10316" checksum="CF07CA6E12D8FC85" modified="2024-11-27" version="1">MLKRTVLFYSNGKWVLTNIDGEHCIPFNLQTPTATLGKVIFNEHLTKNLNKHNGYPDGLSRSPGQYLFSGLGYILTDSRKSDSKEEEVVASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PBM2</accession>
    <name>A0AAV4PBM2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_565951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004426">
        <property type="protein sequence ID" value="GIX94772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PBM2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX94772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="9667" checksum="E19E253E02806131" modified="2024-11-27" version="1">MLEVLTSAITPVGTTTAECKTSTFGVTTSDVTENVKSSTDTPIVTSVPTVGVTTEKSETGMSEVLTTCITPVGTTTAECKTSTLGVTTLMLLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PEH2</accession>
    <name>A0AAV4PEH2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD_REPEATS_REGION domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_99676_1</name>
        <name evidence="1" type="ORF">CEXT_25801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004257">
        <property type="protein sequence ID" value="GIX93492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PEH2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX93492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="160" mass="17450" checksum="73D1F5C9BDA26C1C" modified="2024-11-27" version="1">MLFDFTSDGARILAATTARRLAVIDVERGEQVMSYDNCAFNGRDRAGLAVDPLCPNMAVCSCINGKGLTLFDLRMPLPLDFVYDLHTAVIRDITFIHSSWPFVRNQQGAVLSLSSDGVSKVTTLDGRYLHCFEVGHNANSIALTPETYGTGGEDGFSVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PLT9</accession>
    <name>A0AAV4PLT9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element tc3 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RF55_24064</name>
        <name evidence="1" type="ORF">CEXT_516631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004702">
        <property type="protein sequence ID" value="GIX96824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PLT9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX96824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13328" checksum="97F36364C49E7BC1" modified="2024-11-27" version="1">MSAVAAHGEYSAREVSEADRSVWKALRITLKRYHYKLQHKQELKLPDFDSRRSFANFVFNKMEEQHDWLHTVLWTEMKRISRFLALLTPTIVECGPQKIHMHLLRYPCSSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PXI0</accession>
    <name>A0AAV4PXI0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_752651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005236">
        <property type="protein sequence ID" value="GIY00894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PXI0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="87" mass="10309" checksum="C16BEE0DEABE048E" modified="2024-11-27" version="1">MFLAHHTVCVLCMRDKTVFCERGERHGSVLKDKKRCRLAMHGRANRLQNFEKGEYLCLFLLNISQTHFVSLRKRRSDKGDTNFADWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q112</accession>
    <name>A0AAV4Q112_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_134901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005506">
        <property type="protein sequence ID" value="GIY02821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q112"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11742" checksum="CB3F9F32A64E20C1" modified="2024-11-27" version="1">MNSLHRICVTAFSGPEFSADGKTISRKSEENEWYRNQRTIHSNDNLLKLRTSFIFRNTTIQISLNPEKNKKIHEDRMRNSTILRIFERKKKGKISFKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Q5R5</accession>
    <name>A0AAV4Q5R5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_477711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005499">
        <property type="protein sequence ID" value="GIY02778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Q5R5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY02778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8879" checksum="69F41567AB648366" modified="2024-11-27" version="1">MPGESVRSSHNNAGAEFRLIVHARDAMDHAESFYACLRGWIRPEGENTALMEYSPNFEMSQLFCVIAGSRYCVEHATVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QBC4</accession>
    <name>A0AAV4QBC4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_444561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005989">
        <property type="protein sequence ID" value="GIY06694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QBC4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY06694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="10734" checksum="2689CC8CC3BDE2DB" modified="2024-11-27" version="1">MTSQPSSSSLTQQLHAVVVKCQMVKWSNGQNDFEVKDYGMGSKHAKASKTGGWRELALEDVVDPLNVFLGNVWKNYLKNGCHIIAFWGFYPDKAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJF1</accession>
    <name>A0AAV4QJF1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_240591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006208">
        <property type="protein sequence ID" value="GIY08165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJF1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY08165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="153" mass="17484" checksum="2E73EF277CF1228C" modified="2024-11-27" version="1">MAEERKVSVTSASKQAVGVGNADYAAIFRFTSGEGDFSSGRLEDREMDVIRFGRWDYQSECGIGERPSPRFALEGLGTQKDKTSQRVEEYKSLPETLILQSTLFIIAEERRVCLSPQHPSRQLALEMLIIQRFHFCFRCINMDETVGWRVRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QMA8</accession>
    <name>A0AAV4QMA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_178341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006449">
        <property type="protein sequence ID" value="GIY09959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QMA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY09959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="97" mass="11560" checksum="32A6173D8D517CB7" modified="2024-11-27" version="1">MCRECLPFHYRLLVSPGVSRRFAYGDCSRSYELFKFPQLVFYRYPSQTLRGSEVNLDLHQWAKSNAWLINIFWFLAFVFCAVATERLKGDELCHRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QQJ8</accession>
    <name>A0AAV4QQJ8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein O-mannosyl-transferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tw</name>
        <name evidence="13" type="ORF">CEXT_266831</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006516">
        <property type="protein sequence ID" value="GIY10392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QQJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF46">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043472792" description="Protein O-mannosyl-transferase 2" evidence="11">
        <location>
            <begin position="23"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="ArnT-like N-terminal" evidence="12">
        <location>
            <begin position="16"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="ArnT-like N-terminal" evidence="12">
        <location>
            <begin position="117"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GIY10392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="172" mass="19955" checksum="B3D16376FABCB183" modified="2024-11-27" version="1">MSKSENFQWWMVFLGVTFLAAATRLYKIEEPDHVCWDETHFGKMASWYINHTFFFDVHPPLAKMLIGLAGKLTGYNGTFAFNKPGDKYEDHNYLGMRLVSFKLFLTMLIRNFKKTNFCVFHGIAVIPFCFLIVWELTYSLSASTLAAIFLIFDVGMITLCQYILLDPILMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRW6</accession>
    <name>A0AAV4QRW6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_534161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006568">
        <property type="protein sequence ID" value="GIY10835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRW6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY10835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9927" checksum="3DF1A3F9043323E6" modified="2024-11-27" version="1">MIQFTDCRRTKKGHKKLIPTKEPTSKYNNNANQWQPFNAAHNRNKVSRKRRSVFKSPSDEKSPFEGSQRQRLTPIRKSVSIERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QW32</accession>
    <name>A0AAV4QW32_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_146671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006798">
        <property type="protein sequence ID" value="GIY12489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QW32"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY12489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14606" checksum="4F9C0E9E7C8F5754" modified="2024-11-27" version="1">MCLEVGKNIFSSSLSSEKQIGVEDLQGSHAIEFIDSLHSITVHLQHRCMNVKGTPDCLPTRKRLFASAYDLLSPSGKMTLVSHVYSTFLHGCGIYICSKNNIAVFFFDKYLYFAKQPVMHRLPINIFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QZD2</accession>
    <name>A0AAV4QZD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_674401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006978">
        <property type="protein sequence ID" value="GIY13671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QZD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY13671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7769" checksum="D696E345557872BC" modified="2024-11-27" version="1">MPNCNTFLPTLNDVSQYNARERRREYAGNACWTPCFLKRGDSMGHPREEFVPYGDWSATEFSFEDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R2M4</accession>
    <name>A0AAV4R2M4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_784421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007218">
        <property type="protein sequence ID" value="GIY15254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R2M4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY15254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10522" checksum="69CDF88B2A3707D4" modified="2024-11-27" version="1">MFLYTATLIVYRRIKLVEEIRFKLIIRILRCGVHAEAACIWALFPNTNMSVNDDMGGISSCVSLEVPTHTALKHFVILLFSYYSAHFQHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RD47</accession>
    <name>A0AAV4RD47_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_427161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007573">
        <property type="protein sequence ID" value="GIY18027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RD47"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY18027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13620" checksum="782E2240BE2F611F" modified="2024-11-27" version="1">MTHLQASLVLRWSIKHCRIWKSQSLDPHIRSASSFSNVACSRRITWPTIFGPCDSPAFSEHSTNSACCIDGSVQNWPPIKDSRQITMLEPLQTFSTNMKIDCAVEKKYKSKLKQRNKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RHT4</accession>
    <name>A0AAV4RHT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_393931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007942">
        <property type="protein sequence ID" value="GIY20872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RHT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10565" checksum="9B42001EFF0E9CA1" modified="2024-11-27" version="1">MECFILTSNHRFGRLTRIIYDAGPFKVSSGVVVFASNVRVRVPPGLKPSLIGQQIIFEADRVSMECVIHTSNDRFGMLARIIYDSDTFKVSSGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPA8</accession>
    <name>A0AAV4RPA8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_523221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008195">
        <property type="protein sequence ID" value="GIY22786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPA8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY22786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="117" mass="12773" checksum="B644A7FFC68AAD72" modified="2024-11-27" version="1">MVSSLSLLVPQGMPKEMKDDEDSSAKVYYRRLSGKGHHLSSLNNSSLSCSSDGVLFSVSLLPPRGMPKEMKDDEDSSAKVYYRRLSGKSPSVEISGASGLLNLLWLYITSFVTGHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RPD9</accession>
    <name>A0AAV4RPD9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_322441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008273">
        <property type="protein sequence ID" value="GIY23449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RPD9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY23449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12632" checksum="F674FAF899844D34" modified="2024-11-27" version="1">MDLGKQFCRQHHVQNVHSDYTVVATGETLYMKLHYGVYRSALTATLLERQQKQDSIQGKFPKLNLNGIRSVRFPKHPRKIYRCNSLYIKIFFFLIIFCVTQHTNNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RVW2</accession>
    <name>A0AAV4RVW2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_414821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008375">
        <property type="protein sequence ID" value="GIY24267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RVW2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11143" checksum="E01708C7303D6B65" modified="2024-11-27" version="1">MPLEAEAEKGAAEIRARERADSSVDKTLKHFDKNSNISTDVKENWSGRNRRKGSEREKKIPPFEIDFHPSFYDSIPFTAIRSKASNICGTFPPLFLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RWZ4</accession>
    <name>A0AAV4RWZ4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NHR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">CEXT_418811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008392">
        <property type="protein sequence ID" value="GIY24363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RWZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12887">
        <property type="entry name" value="SPRY_NHR_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.920:FF:000001">
        <property type="entry name" value="neuralized-like protein 4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037962">
        <property type="entry name" value="Neuralized"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006573">
        <property type="entry name" value="NHR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12429">
        <property type="entry name" value="NEURALIZED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12429:SF14">
        <property type="entry name" value="NEURALIZED-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07177">
        <property type="entry name" value="Neuralized"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00588">
        <property type="entry name" value="NEUZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51065">
        <property type="entry name" value="NHR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NHR" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="NHR" evidence="2">
        <location>
            <begin position="97"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="NHR" evidence="2">
        <location>
            <begin position="277"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="NHR" evidence="2">
        <location>
            <begin position="469"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY24363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="637" mass="71510" checksum="79AC9689CEEF2B7C" modified="2024-11-27" version="1">MWNFNKWKGKSREYGEYNLDELHEGDRIGLVRKSNKSLNYYINGFDQGIAAENVPDVLYGVVDLYGMTVKVSITDNYKPTLNKPDQENCTAAVELRNKPYAKELDYDMMICYFITIVDFICLDDFNNAVVITNRPLKHGEIFEVLLEQVVMKWEGTIEVGVTIHSAEELKFPSTMTVVRSGTWMMTRNGVMYNGSTITDDYGYDLDKLKAGDKAVKASIVGSSESPVFYEDVNSPTATNYLEDLQMSQSSSIGGRKNSQAGKETEHANEISKPLEPPFSFYSVRGTNISLDYFGVLATRTRDYDHGLVFSLKYLKKDHLYEVHVYTTNTIWGGTLRFGVTTYEPENQTDLPSSALGLTDCDTWLILDSHLYKNGEVLKRNYALYLPHVTAGDSVGIKIFNDNSLHFFINGVDLGVAELNMPEKLRMVADIYGSVESVMAQNGGAFTNTDSRNQEKNLMCSQFIYAPFAMMAFHENHGKNILLSNENLTACRTAGYNQGIVITYKALLCEEIFQIQLDNLLSDWSGSIQIGVTSQNPGNIMCLPSSALSVKENTWVISEDSVYYNGVKIKSKYGPHLNNLKNRHKIGVKIDSQKNLHLIVNNIDHGIAAENISYPAFAIIDVYGKCKQRRKKISGISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S6Y4</accession>
    <name>A0AAV4S6Y4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">VPS35 endosomal protein-sorting factor-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">vps35l</name>
        <name evidence="7" type="ORF">CEXT_556821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS35L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009120">
        <property type="protein sequence ID" value="GIY29749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S6Y4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029705">
        <property type="entry name" value="VPS35L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13673">
        <property type="entry name" value="ESOPHAGEAL CANCER ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13673:SF0">
        <property type="entry name" value="VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY29749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="874" mass="99220" checksum="313FAB0081018AAE" modified="2024-11-27" version="1">MTHEWQAASKSYDVIKNSWVSKKEEVFDHPLKSSTITVQESKIKRRIGGSNTSSASSSLSGTPKKTISDPLSTFHPLSSALDGIDPLSQFAAGLDPLSQMAEEHERAKEISASRKCRLDDTFEPWSTKKAAILNKYTTSEKLSIATSFLSGGDKVIGKATSSVSDKVKNRLEQLDDFEEGSVKEMLNLSQQEYVNRIEELNQALRESWEQDQRVKALKIGIQCSKLLVDTAVIQFYPSKFVLITDILDNFGNLVYQRIHAKAEHHKPGSKNPTPLPEQFTPDQVPESAKETCRNWEYSKALVRLTKMIRGIGDPLVAAYARCYLCRVGMSVAPEAHEHLRDNFWDFLILYNQLQNNFVKETLTKQNLDFPTYLTFALLLNSVMSAFKPEYIAKRALELVDIMKECDDLGFLSDYMSCAEIWIEYAVKHFTKREVNTFLGDIIKHMSPNRAFEHHYPQLTRIVDRILAHMHDFSIIFSMDKFLPFLDMLQKESVKVDVCKVIMDAFMRYQVETTSDPVIINAAMFICKTIHDSVNALTIDDEKRQIGVLICAFIRKISFGRDFEQQLGFYVEARSTFSNLDSALIQLVQCVNLLAMRTRQIVKGHHTRKTSSFVKACIAYSFITIPSLMDVFSRLDLYLISGQVALLNQCLSQADAFLKSAISLIPDCPAVMEVDSKHKSTEPYLLSYISNLLSTLLIVPDHPEQEPLYLIRGLLNVIQDYTWEQHSDTKVLVYLNVLNLLSALSQETYIWSLDGVDSNDALYGSDPKFITEINKICSTLIDEILAHLKFLGERGNFRKQSYLALELLYHIIAHGDLSCNSLFTLSNNLWLLAHRHGHCDLKSAGNCLTYLKVKASHKWGPYQDLANKLQMPTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S7X8</accession>
    <name>A0AAV4S7X8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Muscle, skeletal receptor tyrosine-protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MUSK</name>
        <name evidence="11" type="ORF">CEXT_25221</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009123">
        <property type="protein sequence ID" value="GIY29755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S7X8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000008">
        <property type="entry name" value="roundabout homolog 2 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="9"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="101"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="195"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="198"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GIY29755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="414" mass="46542" checksum="3F21E55867BA95DF" modified="2024-11-27" version="1">MWRNVGCKPAILEGPRNVTVLSGSSVLFRCAVDGDPEPAVSWQKNGRSLHYAGHANYRVLESGDLKLDNVGLADDGLYHCIARNVKGMDYSAQARLHVEEPAKLKGGRSIYNVSWGSNVRLECSAQGEPPPVITWFQDGEPLDDAYALADPVFTHSELFLNATRTTSFTCKATNSLISLNSSLVTDSKQFQLYVTPKDEDEDEEEEWDDNLPFDVPGSEEDDVKEGEEEEDPLLLNELEEEEEEEKWEEKKEEVSGSGAEKPREESGPFGGGGEVTVGYCAPYTGQICRRYLNGSGHVYYNFTSENHPIPLNEQITTELWSELISSLLEPCRHDMLFLLVTQFLTPEGEYYFDINSIEDKNTFFLSCTFMRKIKEVPSRRSGSWFSIVSGLGLMERRVLGYFGPSADTIFFIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S8K9</accession>
    <name>A0AAV4S8K9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_599221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009114">
        <property type="protein sequence ID" value="GIY29699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S8K9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY29699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="16660" checksum="0203A07A4CB4AD54" modified="2024-11-27" version="1">MITFRGSAKRYKKETAQLLWNIVCKQLAEASGRGLVEGLSDNTKRAIHHISSYRQKRRELNKLGHISVQNKAWYTAKNHTWKILKGQYIILTDYHPRRRKTNKLGHIAVQNIAWFSFGGVELDTPRGLFGHNDEREAQFCSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBM6</accession>
    <name>A0AAV4SBM6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoenolpyruvate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pps_3</name>
        <name evidence="1" type="ORF">CEXT_574311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009250">
        <property type="protein sequence ID" value="GIY30571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBM6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051549">
        <property type="entry name" value="PEP_Utilizing_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615:SF1">
        <property type="entry name" value="PPDK_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY30571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="343" mass="39671" checksum="3E90D967E845456D" modified="2024-11-27" version="1">MISIFWRLLDDPQLLSYAYGKVKPGGKPSVRSILRHYWDLFFYDLGFEKVKKKINNYSLDFLKFKTAEETFTALINSCSDFDEAAEMHIESSESSSEWNMTLLQILSEAKRNDFATLLGTSSNVESAAIPQMIQDISCQIVKDLGNERFRCFSVELGPHGRKPNIGYKRQKLFLDIISENSLKKTWPQMFEGVRCPISYMGYETKLLVKLLQNLAVSTKKEIKKESDSINKIFSQLHITLNFTSRVREAGKSLTIKSFDHWRKGYRRLGKLMVSEGRLPDQDLIFFLTLDEIDDLLKTRSPCIISRARSRRKLFPIVDEYKFPEIMRGVPKPVNDDDKSADMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SE11</accession>
    <name>A0AAV4SE11_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neprilysin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Nep1_6</name>
        <name evidence="2" type="ORF">CEXT_367481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009506">
        <property type="protein sequence ID" value="GIY32415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SE11"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="9675" checksum="58CB2F8636E200A7" modified="2024-11-27" version="1">MVLKATHSPNQSDNLPEYEMLANGNPGKKPAVRIQENPLAEVAVDKPPNDMVQLRIEKGASGASPAPGTASGPPSSCCSASPPSCWGCCAAPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SF34</accession>
    <name>A0AAV4SF34_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fasciculation and elongation protein zeta-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Fez2</name>
        <name evidence="4" type="ORF">CEXT_502491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zygin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009219">
        <property type="protein sequence ID" value="GIY30423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SF34"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011680">
        <property type="entry name" value="FEZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12394:SF12">
        <property type="entry name" value="LD08195P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12394">
        <property type="entry name" value="ZYGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07763">
        <property type="entry name" value="FEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIY30423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24798" checksum="9DA1AD39658D7034" modified="2024-11-27" version="1">MAELKIQAPLARIEDWAEFNDFQCSEDFENSNKDSFSSPEANENSFVDSSFSDAFSTSLEDLVNTFDDKITKCFYNYEENVEKLAPVQVRNQDEIMNECQIWWTLTGNFGSILPIDWTKSCAKGLQHSLINLNQNSDCDSKRDESPNEIDVRSFLIKNLQQEPLFTAEQVLEEIEEMIQQQRSPSLNTCETPDKSPDDLKSKVAAYIGMYKDEVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STL8</accession>
    <name>A0AAV4STL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_603841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010218">
        <property type="protein sequence ID" value="GIY37763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY37763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="81" mass="9020" checksum="3E1AA3EB2FAA00F0" modified="2024-11-27" version="1">MDLLKGRNTHFYEGVGDWGMYPRGTMGSYLEDFPNDLASRLEYLIIIITPSFASPVSPRPEMGFGMGEAICKLKDGESSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SVG3</accession>
    <name>A0AAV4SVG3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mos1 transposase HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_690641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010305">
        <property type="protein sequence ID" value="GIY38453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SVG3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY38453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9365" checksum="802E71DA9F9597E6" modified="2024-11-27" version="1">MALPIVKYNQRYIFFAKDVKAAEILLQISEVYGGNIMSDGFIRKWFRTFKVGNTNIHYGGSRMQSLVVTEDFVQNVEERGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SZR2</accession>
    <name>A0AAV4SZR2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPL14</name>
        <name evidence="8" type="ORF">CEXT_272361</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010314">
        <property type="protein sequence ID" value="GIY38529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SZR2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23702">
        <property type="entry name" value="eL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000022">
        <property type="entry name" value="60S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039660">
        <property type="entry name" value="Ribosomal_eL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002784">
        <property type="entry name" value="Ribosomal_eL14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01929">
        <property type="entry name" value="Ribosomal_L14e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL14" evidence="7">
        <location>
            <begin position="46"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY38529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="18081" checksum="FBA5F7A4D37D1154" modified="2024-11-27" version="1">MAFRHYVQIGRVGFIPFGKDAGKLCTIVDVVDQNRALIDGPCTGVERQAIKFKRLRLTKFRLKFPHSTSSRVVRKAWEEEKITEKWNETSTAKKIAARVKKAEMTDFDRFRVYKAKQQMNRIIKSAYWRLKGKAKKNPAKPRPKRFRGKKVAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T4D4</accession>
    <name>A0AAV4T4D4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_296541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010683">
        <property type="protein sequence ID" value="GIY40975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T4D4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY40975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="77" mass="8775" checksum="5D0D0F602FE1B04E" modified="2024-11-27" version="1">MQLETANQNDDDDDNSHEVCDGDLQSLIPAKSNSNEKHNISHVEKNLELLITEQSDDDMHGISDGEKFIANYSTKWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T533</accession>
    <name>A0AAV4T533_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein Nova-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Nova1</name>
        <name evidence="5" type="ORF">CEXT_435981</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010634">
        <property type="protein sequence ID" value="GIY40611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T533"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22435">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047275">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="7"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY40611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13038" checksum="8F14B78045E235F2" modified="2024-11-27" version="1">MMDGANGTYHFKILVPSVAAGAIIGKGGETIAQLQKEAGARVKMSKATDFYPGTTERVCLITGSIEGIIRIHEFIMEKVKEKPDPNAKIAIDFDNKQPAEREKQVSNKIKPENDAYCLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T6N5</accession>
    <name>A0AAV4T6N5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_181411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010708">
        <property type="protein sequence ID" value="GIY41369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T6N5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="23780" checksum="780B732C9EAB9857" modified="2024-11-27" version="1">MLRNRRLSRTPPVISFLFPQMAASTVGHLISYSSSSRNHRYKSNINECIDRFVINNNSTQNFEYINMLTDSNSNEDYQSDSLHVPLHFLRASPNELEKSTGIPRRANGVHSGTKSSFRVSQRSERSRRNPLGGSFNGSVPLGFANLHPDSAGGVSAQCFLAARVLAIKTSATIRVPMPTPQWPVWKELLGKHSSGLLAKRAWPFVTLCQARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9Z2</accession>
    <name>A0AAV4T9Z2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010918">
        <property type="protein sequence ID" value="GIY43009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9Z2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="103" mass="11902" checksum="763AAED69B7D5ABE" modified="2024-11-27" version="1">MSRKPTRNSILIKISFSACPFKSDCAELLTPIPNAICRTHEIMFKKHNIVTWTIAPQDVIELKKKQVPNVTTTLRKKARDRSSFSSTYYHSILLFSFSRMKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TAP0</accession>
    <name>A0AAV4TAP0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhombotin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LMO1</name>
        <name evidence="7" type="ORF">CEXT_250911</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010964">
        <property type="protein sequence ID" value="GIY43350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TAP0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140297">
        <property type="term" value="F:DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09388">
        <property type="entry name" value="LIM1_LMO1_LMO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09390">
        <property type="entry name" value="LIM2_dLMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000015">
        <property type="entry name" value="LIM domain only 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000016">
        <property type="entry name" value="LIM domain only 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050945">
        <property type="entry name" value="LMO_RBTN_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45787">
        <property type="entry name" value="LD11652P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45787:SF1">
        <property type="entry name" value="LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="100"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="164"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY43350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="272" mass="30532" checksum="FAF737EFA9877474" modified="2024-11-27" version="1">MHIFHLSSVSSFPVINLPEPFIIILCPKVVNWFSQSMELSNFPKCTTLTFCRTLSVVLAGPEIARSLGKNMEIKTEVVPQRKHALSSIVGTTAATRDTLVDCAACRKPIRERYLLKALDQFWHEDCLKCACCDCRLGEVGSTLFTKANLILCKRDYLRLFGTTGLCSACNKTIPAFEMVMRARGNVYHLECFACQQCFHRFCVGDRFYLFENKVLCELDYEERVLIASLPYPTYNSLDQIQRQTDSLIPLSPAVDDASSGYGSPSSLISDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THA1</accession>
    <name>A0AAV4THA1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_790121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011354">
        <property type="protein sequence ID" value="GIY46013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THA1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY46013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8873" checksum="4628446928BD7080" modified="2024-11-27" version="1">MKEGCVEMRVDSKEKGKLKNSTSTQLENVVPWMGGRGTMEFRVQPREPNVEQGEGGAREGEGGGFWSGFLGETFPRAPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THY9</accession>
    <name>A0AAV4THY9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_179531</name>
        <name evidence="1" type="ORF">CEXT_218691</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011349">
        <property type="protein sequence ID" value="GIY45960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="BPLR01016771">
        <property type="protein sequence ID" value="GIY86271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THY9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY45960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY86271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="31" mass="3451" checksum="69C4BB75680E9D9F" modified="2024-11-27" version="1" fragment="single">MLFLPMAEFSDFSLMSESTLKKSLGRRGPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TIN4</accession>
    <name>A0AAV4TIN4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_736032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011353">
        <property type="protein sequence ID" value="GIY45970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TIN4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="232" mass="27372" checksum="149F32CEBB4C6CB2" modified="2024-11-27" version="1">MPFLTEFQNNRFYITAFVPLLLIFISDVAQGYYYSTIERCNLDLKNMSFPRNQKELRVFCGEFKRYYKCVKDLQIPTDELDDWSLILEKSKILVLETCDNRTSRHEGYLRSFPCIFEVMRDSSYREFCKRFTVIALQKFKKYSSLSVAFQTISYDVGWLCIIKSVSVDCLAHFVLHKCGVQDHKVFKDIAENSYFYLLGCQGTWEYLNAKTMISILREPKDLDAFAIVDYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TNR6</accession>
    <name>A0AAV4TNR6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box/LRR-repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_43331</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011427">
        <property type="protein sequence ID" value="GIY46490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TNR6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY46490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10874" checksum="0A4ABDC5EBE02C2E" modified="2024-11-27" version="1">MLFVWTTLCCSKVLRMKSLSKIDTLGVRDCRLSRAGLKELVQKCVNLKKVAFESLDADLKTVAKELKRDIRTTYSHVVSHYFKFQKIYDVHFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TS39</accession>
    <name>A0AAV4TS39_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_25761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011615">
        <property type="protein sequence ID" value="GIY47747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TS39"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY47747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="121" mass="13509" checksum="50799704201ED19E" modified="2024-11-27" version="1">MMLSPGRNQRKGPKYRWHVHRPQWLAVLLGHRWPRAGDVIFCGVLSAYARLCQTRTTTAVEAAVPECDSVTASRHLLAVLKPKTLQMYMSMISSICQFTMSGRCEYGTGFILFVCTAGASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TSL9</accession>
    <name>A0AAV4TSL9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diacylglycerol lipase-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">DAGLA</name>
        <name evidence="5" type="ORF">CEXT_80441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011649">
        <property type="protein sequence ID" value="GIY47927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TSL9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032590">
        <property type="term" value="C:dendrite membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004465">
        <property type="term" value="F:lipoprotein lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF8">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GIY47927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="269" mass="30745" checksum="8CE8491D484CBCEE" modified="2024-11-27" version="1">MVSKLVVLTVVLTVVDFNDDSNCISDLYEHVLGYMVILFGCVVVEAFIAWVSMKGTILIAAPRSSMQYLLYVRLGILVVEVGWLVVGVIWLVNHYPTCPVGLAKDAVLGIVISNWLVLLSVLITTWCTFDAAGRSWVKMKKYQMSMKQRENERGQHVEKPRIRRSGASHRNWRHRKAMREYQDSWNRRCRILFCCLGYNDQKRNNFADIAKLLSDFFPRFGCGPFGCSCRACATPEITANGKRGNSKQARRRYLRISFGRTTYSSNKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TZC1</accession>
    <name>A0AAV4TZC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_464241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012005">
        <property type="protein sequence ID" value="GIY50657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TZC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11568" checksum="DBAC98496810D568" modified="2024-11-27" version="1">MRTPHSESFALPPESPLLLKSKPSPGQELCYTLGLETNRKIRKKKKKENRKFLWIGNQHLYFLVPAENGERKEKNSVFDATKYLLKFRLIKLIDYFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5B6</accession>
    <name>A0AAV4U5B6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_430041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012307">
        <property type="protein sequence ID" value="GIY52925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5B6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="93" mass="10870" checksum="EF374B821A233894" modified="2024-11-27" version="1">MSKIAMWQERPGKFFNDRNQPARVEEVIQNDRRVTLREISLELGLRFGSLQHIISDVLRHFKVCARWVPHALSDEHRANTNHVQSHISSALPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5B8</accession>
    <name>A0AAV4U5B8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-glucuronic acid decarboxylase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">UXS1</name>
        <name evidence="2" type="ORF">CEXT_77621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012318">
        <property type="protein sequence ID" value="GIY53018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5B8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08946">
        <property type="entry name" value="SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF23">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="325" mass="35851" checksum="260B5D845F3FD3A0" modified="2024-11-27" version="1">MDTHSNGQHTEPRNFHHVLVTGGAGYIGSVLVPLLLQEGLEVTVYDTFRFGVSPLLFHAYHPRLKLVKGDIRDKESMTEALRDVDAVVHLAAVVGYPACDQDPVLARSVNVDGTQVLVSCLKPHQKIVYSSTGSCYGAIDGVCSEDTPISPLTLYGSTKADAERIVLDHGGVCLRLATLFGVSPRMRLDLLVNDLTFKALTQGRFSLYQGSFRRTFLHVRDAVRAFLFALDNYDQMKGSAFNIGDETMNMTKTQVAKRIQRFVPSCEIGLGSGEDKDQRDYDVSYARITKLGFRSSIQLDDGIKELVTVLPQMSAAEITFSKNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U6P6</accession>
    <name>A0AAV4U6P6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_634571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012366">
        <property type="protein sequence ID" value="GIY53425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U6P6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY53425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="13473" checksum="1D3869877FDFFC5C" modified="2024-11-27" version="1">MCYERGPGVRRKLLREEQLRSIPSHLTLTNLGGPVSKSPPQRDDYISGKNQGKIDLESTILSVASLKDITVSNSLFLYVAWDVEFKVASNAVSVGTKNFPSSLWLGNFGARKQFISAQPPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U713</accession>
    <name>A0AAV4U713_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_584481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012374">
        <property type="protein sequence ID" value="GIY53522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U713"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY53522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="110" mass="12791" checksum="5AFB9C56249DFFE0" modified="2024-11-27" version="1">MSSQLHRHFTDFKLFLPAVTPPCSYQEGGRGNKIIAIFHLPILFDCDAFEQQSYHLSNCNKIHCCWGCWAYDCNYEFSNCFSPTIEVNFTRADIKLGLLQGVRFIRVEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ULZ4</accession>
    <name>A0AAV4ULZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclin-D-binding Myb-like transcription factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dmtf1</name>
        <name evidence="6" type="ORF">CEXT_489181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013123">
        <property type="protein sequence ID" value="GIY58885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ULZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000139">
        <property type="entry name" value="cyclin-D-binding Myb-like transcription factor 1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051651">
        <property type="entry name" value="DMTF1_DNA-bind_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046775">
        <property type="entry name" value="DMTF1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46380">
        <property type="entry name" value="CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46380:SF2">
        <property type="entry name" value="CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20588">
        <property type="entry name" value="DMTF1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="278"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="315"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="349"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY58885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="480" mass="54658" checksum="648253C35874F2C0" modified="2024-11-27" version="1">MDSPEDDDSLQCDSPDEFTSSKRTVVNAGVQLGFNDECKSILDGAFQNNYSNINMKMPLAIQNCVPSALQVSSELVVITNTGTSFLNEQKVPISSFQPTDVNDSLAKRLCIEQDGQTYILTLQDGMDGFSNIFEMQPKTFQSVDASQLLNFQEPNILQSKEGINQNWFTSKEEKVTLHSKGHIWKTGMWSKEEVELLENNIQLYCKITNPSTVVFEMAKDERKDFYRIIAKGLNRPLFSVYRRVIRMLRSVYGNDWQAIGAAMGRSASSIKDRCRLMKDNCNQGKWLQAEEGRLTDAVYNLANALPGEMVSSGLSWAVVAERVGTRSEKQCRTKWLNYLNWKVAKGTEWTREDDITLINRISNINVTDENEVDWALLSKNWRSVRSPQWLRGKWWNLKRHVPKANVIPFREICDYLYTHLVMKYKVKEETSDSVTNSLELQSIINRPKQTILQSVTLPDTPPPSIVVTAAAQGFPSPLFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UWM3</accession>
    <name>A0AAV4UWM3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_79611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013608">
        <property type="protein sequence ID" value="GIY62316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UWM3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY62316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="163" mass="18165" checksum="B76E80B3848A4D2E" modified="2024-11-27" version="1" fragment="single">ANGFDLKDNLEAWRSLPYAASMYYPYDSAALAGYPFPNGSLSFFSSYLLPFTPVCIFSYLPPETGISGICRTHSISSFDSKTTDTPCYVLPPLFSPQPPTILRIRSNYRDEMLSDVFIISTPLPPPPSTLSLHPLSESWSFVLSNSVLIRERLDGVMLKAVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VCN6</accession>
    <name>A0AAV4VCN6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_606741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014233">
        <property type="protein sequence ID" value="GIY67383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VCN6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY67383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10663" checksum="6BA02E33D802F189" modified="2024-11-27" version="1">MKTYSDKDFRAKLNSSQDIIKLMHTRLQKGMPSKWARIQQKSSNLEKKNHLAFSCTLMPTAFMINKVNLWFDFILCFDKTSTRTIKTGMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VTH6</accession>
    <name>A0AAV4VTH6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein LOC103569155, partial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_4981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015052">
        <property type="protein sequence ID" value="GIY73254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VTH6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="88" mass="9995" checksum="C187C742AED30C61" modified="2024-11-27" version="1">MEVIPENEIDDPANLSFYLPHHAVSNKCGDKFRLVFDGSAKSTTGISLNEKLMVGAELQIDLTTFFIYFRMHKIAMTADIEKYTSKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VV30</accession>
    <name>A0AAV4VV30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ULP_PROTEASE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_240833_1</name>
        <name evidence="2" type="ORF">CEXT_62661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015102">
        <property type="protein sequence ID" value="GIY73574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VV30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="169"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY73574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="282" mass="32519" checksum="EA671A6A85723355" modified="2024-11-27" version="1">MYNYAAMDMHVMQNTMFESSNDVDRQAVYILYPPITIPASLTMTTFAALHTKNINIPKRNCVGGALCFRGHRSFVPSKEAFISRRSIRTYYRRLQNSVRPENDALSVMCNVERLKAEEYNPILLFKPQNSKTLYGPPGLDALLNSDKSFALGIQTETQKEMLIKHSYKIICIDSTHGTNRYGFYLLSIHIQDEYGQGYPVAHFICNYLDYDTLVTLFNSLKCRISNLRVYNVMTDDDNVCYTAFNSVFGPNLNHLLCKWHVFCAWNRQLACKVHSNDLRNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VWJ8</accession>
    <name>A0AAV4VWJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_334661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015212">
        <property type="protein sequence ID" value="GIY74398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VWJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY74398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="119" mass="13653" checksum="2B43528FB96DFF3E" modified="2024-11-27" version="1">MFLNDKRLPGRSTTTGGETQSLKIESEFWTHCKVNEKFPYTVRNPKPQKPEMQSMVFLLGLGDLFVDSKAEPRRPVDPEENDQDERHQVIWIRQVLADCRCVFSLFSTGISSACTWCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W5N8</accession>
    <name>A0AAV4W5N8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_167361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015712">
        <property type="protein sequence ID" value="GIY78051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W5N8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY78051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10093" checksum="B5E19D794A9E9117" modified="2024-11-27" version="1">MYQQLIRNSRAASSRICDRALPNVTQRNWHRYLDGEKIWQRREKTKRVLFVGMEGLRGGGGGGEKMEKWGRRRETAWGVRVERDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WA48</accession>
    <name>A0AAV4WA48_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_4971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015906">
        <property type="protein sequence ID" value="GIY79597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WA48"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9419" checksum="DBC705903BA75EFD" modified="2024-11-27" version="1">MMAQVFRDHMLREVGKSHALIRPLAHRPVPLWTMFHFMVNSPWRHPIWTRLMREADLNNWAERMGLTPESRGRLTPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WAN3</accession>
    <name>A0AAV4WAN3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maturase K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_234741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015849">
        <property type="protein sequence ID" value="GIY79130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WAN3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="11615" checksum="70E352CCB70F99EE" modified="2024-11-27" version="1">MEEPGYLIAWFISSLELKEFVLQFSRYLRYGTKWHQPQSIRRVLSLYRKNEKKNHSLEKWLNGSIKKDFFRRVKMLYFFHLILKSPWFRSAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WBG5</accession>
    <name>A0AAV4WBG5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dual specificity protein phosphatase 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">DUSP19_1</name>
        <name evidence="1" type="ORF">CEXT_659051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015903">
        <property type="protein sequence ID" value="GIY79558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WBG5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008579">
        <property type="term" value="F:JUN kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46377:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01908">
        <property type="entry name" value="ADSPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="152" mass="17438" checksum="B89FB2C9699B4E07" modified="2024-11-27" version="1">MSRDRKSLLLDEVKSYRPTRLRSVETRVTHCGGQQEIERKISTGVIHVGQEPGGRRQWFASDYRPDLQVAVILPGLLLGAQDVAQDLGRLRKLGVTHILNVATGVANCFPADFTYKRLNIRDHPDMEIRRHFDECFKFIDDGRRQGWSVRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WEG0</accession>
    <name>A0AAV4WEG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_346151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015921">
        <property type="protein sequence ID" value="GIY79680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WEG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12653" checksum="9EFD4A4E3D6279C1" modified="2024-11-27" version="1">METYPLNITALLENEKCIQSEQNIQFLFHEIIHRVIKLAKILFGEQSLSKGIRDRTIALSWKDTKPFIILTRAVHRDKRKCLSADWSFVLWKYEDGQHPVRLNVTRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WFK9</accession>
    <name>A0AAV4WFK9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_450791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016120">
        <property type="protein sequence ID" value="GIY81422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WFK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY81422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="70" mass="8165" checksum="312E84F9221C588E" modified="2024-11-27" version="1">MGQKHDGEDDMMGQKHDGEEDRMRQKHDDENHRMGQKHDGEDNRMRQKHDGEDGMMGQKHDGEDNMGSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X376</accession>
    <name>A0AAV4X376_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_103111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017226">
        <property type="protein sequence ID" value="GIY89577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X376"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY89577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="124" mass="14040" checksum="E87815BD16700283" modified="2024-11-27" version="1">MVRYDLEQKVFMNLSFQGQPGVQRTNKDRHNRSRKALGLIQRNERLIFRALGLPSRCKSSVRSFKRQSAKRVYVPSATKCELAGDKETSFRALPLAEFVTQHQGPVGAKMVPNAVQNSPSLLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X436</accession>
    <name>A0AAV4X436_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_805991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017281">
        <property type="protein sequence ID" value="GIY90025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X436"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY90025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="75" mass="8803" checksum="77556EC1CF9AFA84" modified="2024-11-27" version="1">MDSQPRTILNAENVLRLSTAGTDKKIFFLIDTFSRKNPKVGPILFWGVGVEIERCRELHCRRLLLTSRRRVTERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X5B0</accession>
    <name>A0AAV4X5B0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_272297_1</name>
        <name evidence="2" type="ORF">CEXT_816001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017195">
        <property type="protein sequence ID" value="GIY89360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X5B0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043853788" evidence="1">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY89360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="8788" checksum="259E3D241C3AEF05" modified="2024-11-27" version="1">MESSLIILILLLIGEAENEISFVASSDDDKAVYTCATSSIMTPEPMVKSVTLKVLYAPSSVMIKKAQKEAKPGDVISAKNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4X8G5</accession>
    <name>A0AAV4X8G5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_565161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017424">
        <property type="protein sequence ID" value="GIY91512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4X8G5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY91512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="13186" checksum="5A216936709472FA" modified="2024-11-27" version="1">MKGKLHIAAFCTATEHWKEKLEELKKHAWHKFESYSPDFYACLTTKISLMAEAQKRKMVLGEQADILADKALMFYVTVLQYQYSFMLRKKKEVPVEEFYVSSFTINGTSRYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XBD2</accession>
    <name>A0AAV4XBD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_354441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000164">
        <property type="protein sequence ID" value="GIY92571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XBD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY92571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="79" mass="8929" checksum="2DAA69F934014AD5" modified="2024-11-27" version="1" fragment="single">FTEKLEQQYDLFGRQVAILATICFAGVLSLAGQKKMDLRMRLADDDGCRVEAGPKGVDQTNIESPFHSPFRDLHMPKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XF62</accession>
    <name>A0AAV4XF62_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_22971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017713">
        <property type="protein sequence ID" value="GIY93847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XF62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="82" mass="9007" checksum="6C8EDF292F304184" modified="2024-11-27" version="1">MFNTQVCIVRACACHDVDTNMEMPAVDAVMGKHQFSVRIICGQSLMALTLQPWIHGFGGIQNLFRVIVLGCEINLRVSGDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XFR1</accession>
    <name>A0AAV4XFR1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_488281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017596">
        <property type="protein sequence ID" value="GIY92879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XFR1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY92879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9566" checksum="DEFBA45110155D17" modified="2024-11-27" version="1">MPCMIRFSRQAKRLTDSTFPGMVICNGVTDKRGQTFHPPLVGSSAAVLFMYRLLCWMSACAARVRPRKPETVDGNKQMTCTRALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XG16</accession>
    <name>A0AAV4XG16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_247121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01017719">
        <property type="protein sequence ID" value="GIY93896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XG16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY93896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="68" mass="7511" checksum="5D78ABAEEA2B29EF" modified="2024-11-27" version="1">MPEITSVDRMCMCVGWIGAFGIRLPPPYSEGSKLPMRWHEDEFIPSAVAKLHTESQFGVPSPSIAAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XGK8</accession>
    <name>A0AAV4XGK8_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_383471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000360">
        <property type="protein sequence ID" value="GIY94165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XGK8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043461657" description="CUB domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY94165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16633" checksum="293F208192EAC2D1" modified="2024-11-27" version="1">MILFKYLKAILLILAYKFCIVSSDECVIHTGFEGTIAESKYANQFEMCWKIIVPPGSFVQLSLESYTSQYDCPHSTLTVTVLNRDEPYSFCPSGSTEMPIIASDDVIINFKINYGYWFTSSFKMRYKNRQVFLSYHHNKGFAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XLT9</accession>
    <name>A0AAV4XLT9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_62861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000615">
        <property type="protein sequence ID" value="GIY96082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XLT9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY96082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="118" mass="13123" checksum="49BDB6820F7EA4DB" modified="2024-11-27" version="1">MLEVREVYRGRHKSDAPEVKGNNNNGVTEEKVQKYIIMESQQTVAEGREGGVNSKSFRTSERRNAPKPQRSPDGTATISLRRGTDFFRALLIVSVKRSVLSPSLPFTSSTTLQSLLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XS88</accession>
    <name>A0AAV4XS88_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_149551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01000755">
        <property type="protein sequence ID" value="GIY97223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XS88"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="229" mass="25918" checksum="F46B4B7023F762F4" modified="2024-11-27" version="1">MSFKKILTCSRCQRTSSVEDEKFPEDLYALLIKYSLSQILWICKPCYIEDNLTSIEGMHHVEDEIKLLNAKFQKMESDISEIKSVIQKLQFVTNDNFAALFKHEMKMEEGFNFDKNSPKICSLPGYNQNVNSYKGEISGVDSDSSLTSEENQKNLNTFDVIDGCKRTNLHSSSTPKNNRNEGIQAFALSADYQTEDSLSSSFSCSGSFDSNNKILAEANTFQKETKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XT14</accession>
    <name>A0AAV4XT14_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_186311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018266">
        <property type="protein sequence ID" value="GIY98186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XT14"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY98186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9663" checksum="7F4DD2447639215B" modified="2024-11-27" version="1">MNFNDKDYVGNFDGEYGHDDFDGMHNHTVVDGEFDVKYNFVGVFDDKMDYVDYFGFRQSDFDVKYGHAGDFDSDKKGVTDEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XTF2</accession>
    <name>A0AAV4XTF2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_298011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018110">
        <property type="protein sequence ID" value="GIY97023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XTF2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY97023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="155" mass="18368" checksum="0474DBDC07CCA9CE" modified="2024-11-27" version="1">MVPYCHLTENGCILVPYCHLTGNGSMLIPYCHLTEVPYCHRTEEVPYCHRTAVPYCHLTEVPYCHRTEVPYCPLIEISYCHLIEVSYCHLTEVSYCYRTKVPYCPLIEVSYCHLIEVSYCHLTEVSHCYRTKVLYYHRTEVPYCHRTEVSYCHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XU37</accession>
    <name>A0AAV4XU37_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_425791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018323">
        <property type="protein sequence ID" value="GIY98676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XU37"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY98676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="132" mass="14034" checksum="63395EFC2405889F" modified="2024-11-27" version="1">MSTRSGRPARHAPSPPPPSATAAVGCKPLPDFLPADQPVIRRRINFSQSMAAHCKIVISSLKGTAQTADLRHISFAGSQLDERPSLAGHSFDESSHSWTQKVSSTPTVFGVALHSYGTESSPFPCGPLCHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4XX55</accession>
    <name>A0AAV4XX55_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitotriosidase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CHIT1_5</name>
        <name evidence="3" type="ORF">CEXT_345771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018296">
        <property type="protein sequence ID" value="GIY98464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4XX55"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="303"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIY98464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="369" mass="41271" checksum="8EF29E8295A5AD78" modified="2024-11-27" version="1">MELLQLLQQLGANQIQDKLQGKESVEATSTLSPTLPGYRSPNRRRTSAPEATTANTENLFNQYAKPDRSAKSDDKAPVSRVTVRPRGPQYRNSASEAVDAGSDDDNDEEEDISPTSPSGENSRDAFEFPFVYHTPSRHRSKSTTEVEEVLEDYEDDYDPTTTTTSTAKPTPARRVVIKVRPVPGEGKRRNTARPSTNDKENRRNNYVLAQTVGVRRVVRPNVLEEQTTKEEPTPKTTTQRAKPATRPPSPRTTQAQRFRGPPKPKELIVLPTGRPAVPATTRRYTPYRAEPREPALALLPDGRITCLRRGVYPHPKDCSRFLVCVPAEQNEDEYDGFIHDCPKNTLFIDSKGRCVPGDRSTCSNTAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y8M9</accession>
    <name>A0AAV4Y8M9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_237031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018792">
        <property type="protein sequence ID" value="GIZ02286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y8M9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ02286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="177" mass="19901" checksum="BD4B264B3D2C189C" modified="2024-11-27" version="1" fragment="single">VNECLPWNVFCSCKQRARRMRKSNSRTNIRARERQPSDTTPTHKENNSLAQPVITEQKGMYHTAVMQHDNLLVTGKMGSAVAWKSVRKGSDSAFRGLQHTELRNGLMVKNSEYRLMPEQYSLWVGVMACVSAHKLESQPKKGALLMGPSQRDLVPLPATHCLILPHSHPQKQASTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y920</accession>
    <name>A0AAV4Y920_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_374051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019020">
        <property type="protein sequence ID" value="GIZ03976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y920"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="122" mass="14367" checksum="E72F2DA9A9EF0FE6" modified="2024-11-27" version="1">MEICVKNLCFLRRRGIRKGGCRRYGGPRNRDRSMWTPKLWRFYNGWTTPGDLLSALRPSMKPNKSNMKLPTFKQDKKRQKFHKKHALYTSGKPKTKKPYKQAKKSTLPLKNCTLRTNNSKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4Y9B5</accession>
    <name>A0AAV4Y9B5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spidroin_N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_194607_1</name>
        <name evidence="2" type="ORF">CEXT_337961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001637">
        <property type="protein sequence ID" value="GIZ03678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4Y9B5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="378" mass="41680" checksum="1DEA89201ACA445F" modified="2024-11-27" version="1">MQGEPYEMEGRIPGPYSWKYGAVPQSGQQDQQPFMFMTGERQPTENKGGMSLMGARAPTKENYAIDMYPDENEPSSETYAQEAMSPQDTSNFESPTAPEEGQEPTDSSEASSPHLGYGVKPMRHKPLGGAPAQLMGAPTDIDSTNSDQFQDVDGDNKPMDMEYGEPYGMEARIPGPYAWRYEMVPQQESQPFMFRTGERQPALNKERIALMGMRPPQNGNIRINMYPEGNEHLAKITTKDSTSDEKMTTESNEDQNLGQGVNPSEYKPSESSNLLGAAAPKPLTSTTVDIGVGINKGDLITNSDSSYNGIELDEDITVYINGKPVGEKDIKEFFNNQGKLQHFEEHSPQEKSSMGPLTMQAPSSLQQSSSTNKENTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAA4</accession>
    <name>A0AAV4YAA4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_125011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01018935">
        <property type="protein sequence ID" value="GIZ03341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAA4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ03341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12347" checksum="E29DCC2F083456C5" modified="2024-11-27" version="1">MECSTEINVCHPIKYKEDILDLYWTKQFTYKGRWQQQLLEAPSSFTQAANGVVNVIAQESPSPSWKSLEGRHKRARRSRCGHLKVIDSAGIRLRGVFEDHDVPRFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YAL2</accession>
    <name>A0AAV4YAL2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_396571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001695">
        <property type="protein sequence ID" value="GIZ04173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YAL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIZ04173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="15508" checksum="541ACBFE35E03E61" modified="2024-11-27" version="1">MFTRLGLGYNYGYNVYDRRFNDVALGYRGVVGINAPLVGLGGIRGLNVAFSRIPLFPGYPAAVPLVSSVPYSYGVIAPTAVIRDVRDSAYNVQAAGLGYNYGYNVYDRRFNDYALGYRGVLGFNRPLVRVDGFHGFRKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4YBT4</accession>
    <name>A0AAV4YBT4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_318131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019013">
        <property type="protein sequence ID" value="GIZ03929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4YBT4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIZ03929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="355" mass="35552" checksum="268C6470E566A2E6" modified="2024-11-27" version="1">MCRRISLCPARKKKNDGVCQLPPPPPTTAAPQPPVTTAAPQPPVTTAAPEPEPEPEVPASSSAPEVPASTSAPEVPDDSGADSSSGESSESPASEENSSESPESVDDESSSSEESQSGESSSPEGPQSDESSSSAESESGEAASSEKSQSDEVASSEGPQSDESSSGSKSDEAASAEDSQDDGSSSSEGPQSDESSSESKSDEAASAEESQSDEVASSEGPQSDESSSESKSDEAASAEESQSDEVASSEGPQSDESPSESKSDEAASAEESKSDEVASSEGPQSDESPSESKSDEAVSAEESQDDASSSSEGSQSGEVASAEDVQNDDSAASDEKSENSEAEAADQSEPAAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M639</accession>
    <name>A0AAV4M639_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">THAP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">CEXT_741321</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019390">
        <property type="protein sequence ID" value="GIX67310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M639"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.210.20">
        <property type="entry name" value="THAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026516">
        <property type="entry name" value="THAP1/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006612">
        <property type="entry name" value="THAP_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038441">
        <property type="entry name" value="THAP_Znf_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46600">
        <property type="entry name" value="THAP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46600:SF11">
        <property type="entry name" value="THAP DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05485">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00980">
        <property type="entry name" value="THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50950">
        <property type="entry name" value="ZF_THAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="THAP-type" evidence="6">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIX67310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="140" mass="16398" checksum="88024D06FFAB7216" modified="2024-11-27" version="1" fragment="single">QLFYIFIKSDKSGIEFLNIKMVKKCCVPCCRSNYDPTVYISCFQFPKEEDRRNLWLKKINRKDYSPSSKNAIVCIKHFSEKFVITEDHAVRDNGSVLTVKRIYPKLTPDAYSSIFPNQPAYLSSDPVSKEKLHLNEEMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4M870</accession>
    <name>A0AAV4M870_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_657041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01001916">
        <property type="protein sequence ID" value="GIX67977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4M870"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX67977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="85" mass="9932" checksum="EDCA341D15D4EC59" modified="2024-11-27" version="1">MTTPLHLARQSIPTPYPIPIVRMRVKYPFSTWDFTQRSPYLRLEGLLHSGPDELTGELRLKEPEGLPPYRWSIDRLRLKSSEARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MAM5</accession>
    <name>A0AAV4MAM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_810911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019543">
        <property type="protein sequence ID" value="GIX69064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MAM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="184" mass="19895" checksum="3994067A456E3323" modified="2024-11-27" version="1">MDQSLAKRSSRPGVGFPAPDGIVTTTGVIKREQAERAGGPSAGRARHPRDGHPFLAGERPPPLQHRGGHPAAVGGAQADGGAQDLPDTLVMYGAVYCLLQLLPGVRRPVAAQDRHQEGQRPSSSLNQPLFLLYTASFPINCPGPKTRMGHFNSHPPFFLFLLNIQEYIVQLTRICCISFQLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MBN0</accession>
    <name>A0AAV4MBN0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">X975_14759</name>
        <name evidence="2" type="ORF">CEXT_800491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019625">
        <property type="protein sequence ID" value="GIX69853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MBN0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX69853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="135" mass="15783" checksum="6D8183009B81487E" modified="2024-11-27" version="1">MPPPGFEPEAWDTKDQSDNHLAVSWSPCKESLIKKKKNLLAPGREEEEEEEEEEEEEEEEEEKEIKEHVEESVDEVFLLERKRKHSLKYKRSFFVRMVSDPKLYNPKIVRALSTTSSRRHTSDPVDSETGVITPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MDI7</accession>
    <name>A0AAV4MDI7_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_545041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002007">
        <property type="protein sequence ID" value="GIX68879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MDI7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX68879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="22189" checksum="6EC33FD07D458B3A" modified="2024-11-27" version="1">MDINELFGSEGLELEDEFLDFLEKTKENLSRLNQQKVTMVKILQKMKSQIQPFEILLSERVSLCNLALSWSKITPEDNNLGHLVFDYCMQMFKGIALLITINRLTLRQELNDKRIFHTKKTPIILPLLCIILAFFWQWGVGMFPLLALPFLSVGNEGIRIHHLPQLCQRNCPQHDIRPDVARTIPCGATSDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MGC1</accession>
    <name>A0AAV4MGC1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_190621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01019753">
        <property type="protein sequence ID" value="GIX71443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MGC1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX71443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10069" checksum="AD4588C8EFC82200" modified="2024-11-27" version="1">MEVVFDAHGMSDVALNGRFRMETVFCSVLALAVGSLDVEWGSASSAPVNTRRHKILYLVEMKPDNKTLFFFIVGARSQVAQPGRDFGFRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MI04</accession>
    <name>A0AAV4MI04_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase suppressor of Ras 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ksr2</name>
        <name evidence="3" type="ORF">CEXT_384101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002188">
        <property type="protein sequence ID" value="GIX71081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MI04"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF974">
        <property type="entry name" value="RECEPTOR-INTERACTING SERINE_THREONINE-PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="112"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GIX71081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="501" mass="55340" checksum="15A69246AC237FAB" modified="2024-11-27" version="1">MATSSSPFHERDPSAAASRRGRGPPQQSLAPQRGGSDILSPRSSVSSHGSFMSPASTPDIDGARMRRDKLVKQASIKWERDVIKSSLIANVSPSEAPKRPDEHSRLKGASPKAAAAKLGEAGWSSPFCQRRKEAKATTPSFVRPPCLQGQDPERGEQGGAEREPLRHVAPRGKRGTILGKHPLSLIFNTVFNFKTRSFNKEIVDEAETDCIEEADENCFTLSDFRSDSQNGEESLKEWYIPFGDIEFRKEFGTDEKGTSTRAGGTGGADLHHPAELQPGAQPVHGRGGPDGDDTAREHRPLHGRLHRAAQAGRHHQGMGYLHAKGIVHQKLNSKNIILECRVKVCIMDHGMADQQLDRGDYGCIPRGHLSYISPELMSSLQIDPPRIYTTEPCTQESDLFAFGSLLYELLAERFALHDQPPHAIIWQITAGKTAALHNFRFVNGLKTLIKRCWSVRPEQRPPFCEIGHILQENVSHHRRHSCSEPDLLHHAGQASGRILCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MP84</accession>
    <name>A0AAV4MP84_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_152171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020042">
        <property type="protein sequence ID" value="GIX74199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MP84"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7761" checksum="DC6EEF253610F044" modified="2024-11-27" version="1">MKEFKIISVEKIFNGHLTLQQHFTVCGHREANVKQMTVHLMRTVRTQVLTQEDILVSQIEARLNSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MSD6</accession>
    <name>A0AAV4MSD6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioredoxin domain-containing protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TXNDC11</name>
        <name evidence="1" type="ORF">CEXT_580681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020104">
        <property type="protein sequence ID" value="GIX74865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MSD6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052792">
        <property type="entry name" value="Thioredoxin_dom-contain_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46497">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46497:SF1">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX74865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="218" mass="25079" checksum="761EF46819D99BE7" modified="2024-11-27" version="1" fragment="single">AVVVAYFEFKNSSYPRGYKQFYYAAIKALSNDPDRRICFAIVTNKNAAEGFRLRARLQMFLWNRTEIYPGDVKGHAELLKWAYDILEFTSDWVSPPGTKSTMLSEILSENAALVLFTPRSLLLEYTPYYNLLKEVALDYNNCNQSSLVESIKHRLILKRHIMQEEFSKTIRKCHKNDTAHDPDVCRLRPDLCDLACCQTTSLSLNQTKHVPAVLACIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MV10</accession>
    <name>A0AAV4MV10_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_502141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002650">
        <property type="protein sequence ID" value="GIX76133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MV10"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX76133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="255" mass="30611" checksum="E2A861DFA8DCC140" modified="2024-11-27" version="1">MRENVEKLQSQLQKSQEERDTAKRNTKNWLKNRINRIQIYKLQAKMDQVKTDWEKTNLELEKLQLTSTKTKEEYKSTVDELEKLREMHSRTSAQLTISKENEEKIRVDFDRCQMELNVMREQYDKSQESLRKSQTQIDKMHSELDGLRNELNRVQAQVGKTQTSHEKSQEQLSRSQTELEKFKEQVDRLQSELNRVHAEKDRLQTENVSLKAEIERYQSQMLKHHTTQEKAMLEIESLRDELNKFKEKQEKLTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MVS8</accession>
    <name>A0AAV4MVS8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_764571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020271">
        <property type="protein sequence ID" value="GIX76627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MVS8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="83" mass="9035" checksum="84780391BC91F128" modified="2024-11-27" version="1">MKCQIGCSDLKWGKESISQTFAPSRKIQGLVKSTSVEGGGSFPVMRLFTRIESGIQAENGGKRVNLLLDFISCRLTSNLGVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4MWR3</accession>
    <name>A0AAV4MWR3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_220591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020285">
        <property type="protein sequence ID" value="GIX76884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4MWR3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX76884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="489" mass="52540" checksum="A3A6D674630C2449" modified="2024-11-27" version="1">MITGTPIIDCSTPLENSRLSADSLSSFAIQLIFYYIPCALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKILLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLALESVVKSKKVLLAERGFDPRTSGLWAQHASTAPLCLVKRVVIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N3X5</accession>
    <name>A0AAV4N3X5_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">CEXT_720551</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01002846">
        <property type="protein sequence ID" value="GIX78530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N3X5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIX78530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="86" mass="10005" checksum="8BACDE3EDF3D5907" modified="2024-11-27" version="1">MVWIHGGFLQFGNGNEPGISPTAKLAKKMNMVFVSMNYRLYTLGFMALDILTDDILTRFQRKLWLMGSVMCPPVGQRKHQKLWWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4N642</accession>
    <name>A0AAV4N642_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_712911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020574">
        <property type="protein sequence ID" value="GIX80173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4N642"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX80173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="11991" checksum="816023F5077F43AA" modified="2024-11-27" version="1">MIIDRIGLNKSTNGALRNMLLSTFHGYKMKHLEIINLKFSSPPHSFITVKKKTNKTLSIHSNSEAGLNETGTKLPEFLFSQLSLWCCAPPNEGCCIFAADCWAFQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NCV6</accession>
    <name>A0AAV4NCV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane progestin receptor gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PAQR5</name>
        <name evidence="8" type="ORF">CEXT_806292</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020754">
        <property type="protein sequence ID" value="GIX82170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NCV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF141">
        <property type="entry name" value="MEMBRANE PROGESTIN RECEPTOR GAMMA-B-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIX82170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="412" mass="48487" checksum="07B2683BE4E270E4" modified="2024-11-27" version="1">MNKRKKVALSSNSEIESCNWDATMASTYYDKLLGNQFKKVTKLSPVLFRSWIYVQTKFNLFMSKLCLSEETKNFFFFNAYKTKMSQVLNSAPNVSLYKEEEIPPHLREVAILTGYRSPSSSVKECALSVFFATNETLNFWTHFIPTFYFLYQMLLFWDTFKIIDDSYYWPFIVYMCTICLYPLISSLAHTFCSTSDMARHVWFFLDYGGLSLYAYGAGLLIKAYSFPEELAHTLMGEYFLEILVFLTITCCISACFSRFIENLFWIKVFRLGAFFLPWVWDSIPVVYRVSFSIDVQPAVAEHYILQFFFSFCIFFFYASHLPERLAPGKFDFFGNSHQLLHISGIMATHHQMSAVIVDMKDRRAKLEEKYPLPEFWSIHIFSLVLFSITSAILIFIIWARHYEKNRMEKRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4ND16</accession>
    <name>A0AAV4ND16_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_731811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020721">
        <property type="protein sequence ID" value="GIX81861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4ND16"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX81861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="107" mass="12432" checksum="DA81C0D7837C54F2" modified="2024-11-27" version="1">MRIKTHLRLREIETERDRETTKQEKKRFVRERGDVSSGSRFSWSGFPVKGKTNPSSWDKVSFRLLGVLEDGPLFGVTFISLFNGAFIPPERFPGDWWKDRFPVTVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NE29</accession>
    <name>A0AAV4NE29_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_230941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003208">
        <property type="protein sequence ID" value="GIX82128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NE29"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX82128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="14381" checksum="FD20A2EE093E1B5B" modified="2024-11-27" version="1">MESSRQDIGLGKRVIGRLSGRGLNGFTSALVSLLQGGFFLFRRRFRCQFLEFSHPDIELAKLVIGRLSGRRLNGLISALVPPTKRFLLLEGEGFMQNVPAFIGNIPSCKIIYSLSQVLKSVYDFTISND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NG49</accession>
    <name>A0AAV4NG49_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prodigiosin synthesizing transferase PigC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pigC_0</name>
        <name evidence="2" type="ORF">CEXT_302731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01020855">
        <property type="protein sequence ID" value="GIX83295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NG49"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055492">
        <property type="entry name" value="DUF7064"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23212">
        <property type="entry name" value="DUF7064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF7064" evidence="1">
        <location>
            <begin position="139"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX83295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="311" mass="35041" checksum="73EBDEE9564C5160" modified="2024-11-27" version="1">MADSWIYLKLADGKTYTLPDSCGFQQPFEGNCQRFTCGKLQMHYLSPMRRWRIFYCGMLNETSCDKKTTEEVFVKFVFLYSFVGRIRLHVGHESQRICKCHSEAKWKKPCVPPVEEFESRKNPSIVESKCISILGTTPSNGFSFHVSEMSTKHLFKELPIGFTVDPEGELDVLKDLNVSVKKGTSEEYPRSFKARFHTGERYEVVGKLMEPIFIQAYQGVDGSMELSFIEFEVGKRKGYGLLILGEVNSAPNISMTKPIAPTTSFPESIPLTVKFTDEASHFGEISGGKGSSLGKLTQLSQKEKSVCLISM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NSR4</accession>
    <name>A0AAV4NSR4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sorting nexin-14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Snx14</name>
        <name evidence="4" type="ORF">CEXT_314721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021236">
        <property type="protein sequence ID" value="GIX87439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NSR4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF44">
        <property type="entry name" value="SORTING NEXIN-14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="3">
        <location>
            <begin position="5"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="284"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX87439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="441" mass="51555" checksum="59308A46B48DD508" modified="2024-11-27" version="1">MDCAKWKSTRLLEEILEIVIEKHIYTWYRTISKDEDFVQEIRVSLRFLFSSLLRRALQVDIVKLITEKAASALCKHLDCYLQARKYHKSHLRMEETVLCFLGDKLHPALQNRQSELSYLRELTSNLLPFIVQQKYLNCGTATLVKFFVWCQTRDVLTPSVLSNFEKQATLSRCERQLIKEGIRKIPVMCKKKPSLVCAELGQLAHFRSSAHTKTNQFIIVLESDLLVIILSDNKLVDVINHLLILFFDKTPMSDLPDSKLPKVEFLSNFVSSHVSNKRPVLYTDFQTILEDQRLLYVFMQFLKEESSLNVLQFHLSVDEFNTRILNPDLSKEELEALHLQAQQMYNTYFASHALDRINFDDEIVQEIKSIIAGPSENVIKLRTTTPLFRAYDHAYKLLENIYCPMFFFFLCKVIGILVYFVEKGLAILVQKHQERVVKRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NTW3</accession>
    <name>A0AAV4NTW3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosome biogenesis protein BMS1 homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BMS1</name>
        <name evidence="4" type="ORF">CEXT_686381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003714">
        <property type="protein sequence ID" value="GIX87833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NTW3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AARP2CN" evidence="2">
        <location>
            <begin position="93"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome biogenesis protein BMS1/TSR1 C-terminal" evidence="3">
        <location>
            <begin position="539"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GIX87833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="823" mass="94681" checksum="801AE38C65F2C75B" modified="2024-11-27" version="1">MMIDLVKIADLALLLIDAKSGLEMETFEFLNICQIHGMPRLMSVLTHLDLFKNVKAQRSQKVFLKKRIATEIPRCEKMFYLSGMLHGEYLKNEVHNLGRFISVIKYEPSSWKKTHPYVFVDRIEDITDPETMAKDPNCNRQVCLYGYARGGALKRNSHYHIPGCGDYLIRNIHFLPDPCPLPDKLKKRSLNEKERLIYAPMSGVGGIVYDKDAVYIEMKEDPNKDKEEEAETDKLLRSMAAVQHPIDEKIKAAPLQLYPGSEPLADQDGLSSDDEENEDDNDEEDESDDDFFNGNGFENSESEDESSDNESDHDDFGEELNEKGSKRKVRFAEDDNYNSSSDEDISDSDKKLPKKKKKIEADSDQDSDFVEMGEAKWKDNLVKRAADDFYERQKKSVSLQRLVYGQSKPKIQESDDSDSENEIGGLFRIAKHEKEKKNSMSDNALDCSIFEIAVQRDWTNEDELLMIKDCFVTGKWADDEDAEHLLNEDDDELYGDFEDLETGTVHKGKEKISKEDSEGEENSEEIKAEDEKEPETEKAKEQKEMTLKEKRMEKKKKLKELFNQQFDDSKERAYHDDLKMEADAQGELNKTEFEGLDDDVRVQFEGYRPGLYLRIEIDDMPCEFVKNFEPCYPLIVGALLKGEEQMGYLQARIKCHRFYRRQNKQLVLKSGDPLILSIGWRRIQTAPIYYKVEDNLRCSFLKYTIQHRFCMAAFWGPITQQKSGILGVQTVSEITLDFRIAAVGSITEVNHATNIVKKLKLKGYPREIFTKTAFIKDMFTSPLEVAKYEGAAIRTVSGIKGQIKKALRVPPGDFRATFEDKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4NUG0</accession>
    <name>A0AAV4NUG0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Potassium voltage-gated channel protein Shal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Shal_0</name>
        <name evidence="2" type="ORF">CEXT_337801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021319">
        <property type="protein sequence ID" value="GIX88411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4NUG0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX88411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="168" mass="17900" checksum="3125E373C0CD2669" modified="2024-11-27" version="1">MARIRIAKATTGAAFVSKKKAVEARIAARESGQEVEDFPDDIFRTAASPPAQVPRENHAENIILQSCCGRRCSKKSYQHHRGTTVSDHEEELNDVQVRLQNRTSPDGGHFHRPSLGNATVATTVSSSGTATVVTLPHPDSDRNPATISPPGTTTSTTSGGGTVRISTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P0T0</accession>
    <name>A0AAV4P0T0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_305101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01003802">
        <property type="protein sequence ID" value="GIX88857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P0T0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX88857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="123" mass="13938" checksum="552EC307D0CBA15A" modified="2024-11-27" version="1">MSITSKSILCCHFYGPNGFGRPNLTENYLPIHSSIEFLCLGQRSLTIAGIGQEIRKMRFGWSVDEMLLRGLMVFDDFLTPPRPLCRVWLTSIRYTIRFERFGLLLVLGPVLNAASAINIDNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P1C3</accession>
    <name>A0AAV4P1C3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_324511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021384">
        <property type="protein sequence ID" value="GIX89037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P1C3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX89037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="129" mass="15003" checksum="6516884B28BB0424" modified="2024-11-27" version="1">MGLWDCCTTEEEESSLETIPKANIPQSKNRHKSHLRFPLAILIPVQTSMFDTDSRPPKRYPISYLKNVPIRHKARGASYSSVSDMDPNSSSWLPSWPEWSARRAAIKELQWRERMKRLEFFNPPESSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P2R3</accession>
    <name>A0AAV4P2R3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">fut-6</name>
        <name evidence="15" type="ORF">CEXT_618571</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="BPLR01004030">
        <property type="protein sequence ID" value="GIX91502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P2R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031481">
        <property type="entry name" value="Glyco_tran_10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17039">
        <property type="entry name" value="Glyco_tran_10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="5"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="132"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GIX91502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="213" mass="25063" checksum="19D04A29D40B854E" modified="2024-11-27" version="1">MKDFKLILLWTSFFGYWEYLPKENFKYCSRCRNCRVTTDRSRLKESDAVVFHARDMSLSDLPPVRYPHQRWVFYCLESPPYSDFPGLQHMRNMFNWTMTYRTDSDILAQYGSVTRNYPSRKLDMQSLYSSFTNKSKSVVWMSSHCPTDGGRDSYVAELRKYIDVDVYGTCGTSICPEGATEKCLQEFAQKYKFSWHSRTPSAKTTSQRSFSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4P729</accession>
    <name>A0AAV4P729_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_605731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004164">
        <property type="protein sequence ID" value="GIX92818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4P729"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX92818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18993" checksum="A223769CBB2C34D0" modified="2024-11-27" version="1">MLIKGSEFPRKKHAGTCCPRRFSARNIPIFFHQVCVGNFCGKKATCMTGSPDRSRCSRASHHPPTEGKVKAKAAFAEEHPFHFKNKLRRDYLSTFCMRLLSLSYLSIGRNGIVVFILFFLFPPIYRQLLLLSSLQFMLASTFYCDLDNECRCSSSVKERSAVRPLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PAV8</accession>
    <name>A0AAV4PAV8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_23551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01021719">
        <property type="protein sequence ID" value="GIX92831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PAV8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIX92831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7804" checksum="692FD0A6B6EBA9A0" modified="2024-11-27" version="1">MKKKKKKEKKESEREAIQCSLHPPRGFVAAVGRLSLIGGGGSNGSTFLMRTEINVRLMCLKRGARSNGMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PDS1</accession>
    <name>A0AAV4PDS1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_510281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004486">
        <property type="protein sequence ID" value="GIX95266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PDS1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="9014" checksum="2FF0AF5CC7031F30" modified="2024-11-27" version="1">MNGLMPGLRRPRILEKMDWCRTSGNISGKDQLDECRFLLNPTIPPTHSTATSPKAYAYANPTPEGLNMSRAKRKRKKGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PE76</accession>
    <name>A0AAV4PE76_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BTBD3_0</name>
        <name evidence="2" type="ORF">CEXT_495231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004554">
        <property type="protein sequence ID" value="GIX95717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PE76"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022008">
        <property type="term" value="P:neurogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774:SF4">
        <property type="entry name" value="AXUNDEAD, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45774">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX95717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="308" mass="34650" checksum="892FC7C68878E6AE" modified="2024-11-27" version="1">MCDITFEVGPEATVFKAHKVVLADCSPVFDTMFFGSLPETGDKIIIPDITPVGFKMLLGCLYEEAIHFNTEMEAFETWAAAEKYCIKNLKEACETFILNCTLSSSNIWCLLENALVIDQKSVVSKCKEYLEKNTDSCLRAEGFLQLSLDSISCFLEISNSDVSEMILLKSLITWGRCRVKEGKASTLRDSLQTVIGCIRFGTFNKSEIMALFAEAPDLLDAFESTSIIQHLVDPMDYPLPEWCCRITWPRSNFCESDMKIDKASIKLSKRQKINKSCCGSRRIAVRVRDAVHMDKNGNFSCCESSSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PEE7</accession>
    <name>A0AAV4PEE7_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_238681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004332">
        <property type="protein sequence ID" value="GIX94091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PEE7"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF40">
        <property type="entry name" value="REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="1">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX94091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="167" mass="19291" checksum="3FB219D5B3132373" modified="2024-11-27" version="1">MSSSLSDTALEKKFQGATNTQDSIQALSLWLLHHKTHHQKIVAAWMKVLQKDDLDFLKINRLLDNFLCYVKEVIQCSSINRVHAKSVPIVNYINLQFIDFWKLLLLVRDEHIRSSILRVFDIWEQRSIYSPAFIADLRAILANSKVPSTAESKLLADFKPETVINKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PRK9</accession>
    <name>A0AAV4PRK9_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SF1</name>
        <name evidence="21" type="ORF">CEXT_201181</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="16">Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.</text>
    </comment>
    <comment type="function">
        <text evidence="18">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the BBP/SF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005064">
        <property type="protein sequence ID" value="GIX99565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PRK9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22382">
        <property type="entry name" value="KH-I_SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000016">
        <property type="entry name" value="Putative splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.60.10:FF:000031">
        <property type="entry name" value="splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 18" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14 18" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="15 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 18" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9 18" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 17 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="20">
        <location>
            <begin position="341"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="132"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="380"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="602"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="620"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="647"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00055181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="GIX99565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="659" mass="71116" checksum="C22C3F69052C6750" modified="2024-11-27" version="1">MSGRTSGANTTPLGRPSPSMLGSSNKSSSSMLKPSYMTSSENKRSREDDYDYQSAKWPEENSWPSNNHNDKSESEREKERKRKRRSRWGGDEKEKVFIPGLPTVLPNNLNPQQERAYLLQLQIEEISRRLRTGDLGIPPNPEERSPSPEPIYNSEGKRLNTREYRTRKKLEDDRHSLIQEMYSCNPEYKPPPDYKPPLVKVCEKVMIPQEEHPDINFVGLLIGPRGAKIIIRGKGSVKEGKVGRKDGQPLPGEDEPLHAFVTGNSNESVKRAVLKIKDIIRQGVEVPEGQNDLRRMQLRELALLNGTLRENDGPRCTNCGGTTHRSWQCPDKPNVTNNVICSNCGSAGHIAKDCREQKAAGGAGAPDKAKIDQEYMSLMAELGEGPPPPKMSMGNTSQSSITPLQAPPGPPKAIMAPPSSSSSQYQATSSQSIFTSGQNKSSVAQNMPPPTTGMQNAMFVPPPVMSQMPPPPMPPSTVPPMAMPPWSQPPFQVPPGVPQQPMMHNQGAAGMGMLAPPPPPPNFPVGNQMQGNWMAPQAATQAVPWQMPHQVGGPMPVPPPPGIAPIPPPSAMATMYPWGGYMGVPPPPSAAASLQSAAAALKDLQSLVAQPPPPPPPTTAQPTQSTTTSTSQNVSLTAISLPELLAAPPPPPPPPPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PSQ2</accession>
    <name>A0AAV4PSQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase UHRF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">uhrf1</name>
        <name evidence="10" type="ORF">CEXT_114283</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004878">
        <property type="protein sequence ID" value="GIX98232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PSQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF45">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="YDG" evidence="9">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="136"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GIX98232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="215" mass="24469" checksum="FCBF4EFD22D2580D" modified="2024-11-27" version="1">MKERNSNILGVVEEIYQETNDVALSSNCNVAINKNEAEAKDWKAGKLVRVVRNCKGRKHSEFCPEEGNRYDGIYKYPEGYLESLEEKQKAASENGSEKKRKNDDINKKFWDECLEVVSICNGQQEFLKKVENTFSCICCQEVVFIPITTICCHNICKSCLNRSFKAGVFSCPMCCQELQKTCINDTNKNLQNVLLCLFPGYDAGRSLKLCASDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PT24</accession>
    <name>A0AAV4PT24_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_775681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01004894">
        <property type="protein sequence ID" value="GIX98352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PT24"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIX98352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="187" mass="21939" checksum="10886B9E7F643385" modified="2024-11-27" version="1">MVLNPQQQNFINSKLSGSNRSTILLRTLWIKQKHHSAENRYLSNNTSQTNDPEGVPSILGSPEDCPAISRSVRDMSPSHLLQKSYESMFRKQDTILGFFKSNEFEEFSDFFDEFDEKIRCRVIISLRDLFSIFSSIKWISSFRFTSEFDNNGFDLFGTMLWQCVSRNDVTEHKREMKHSIWGKSRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4PW30</accession>
    <name>A0AAV4PW30_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_755391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01005240">
        <property type="protein sequence ID" value="GIY00940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4PW30"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY00940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13381" checksum="2C83CAAC4D9290A3" modified="2024-11-27" version="1">MPSTKFVTTYFFPFPVLQTISILPHLSKSINGATFKTKAKSHNDQSQKNSSTVKTEPKCVINMLSVTSEMCTKRFPRADLTSLLNYHEILMYKPRARFLLTAKHLCFADRRMKLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QE62</accession>
    <name>A0AAV4QE62_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Putative inositol monophosphatase 3</fullName>
            <ecNumber evidence="6">3.1.3.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Inositol-1(or 4)-monophosphatase 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Myo-inositol monophosphatase A3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">bpnt2</name>
        <name evidence="17" type="ORF">CEXT_813031</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="BPLR01006232">
        <property type="protein sequence ID" value="GIY08333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QE62"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008254">
        <property type="term" value="F:3'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052834">
        <property type="term" value="F:inositol monophosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01640">
        <property type="entry name" value="IPPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000012">
        <property type="entry name" value="Blast:Putative inositol monophosphatase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000007">
        <property type="entry name" value="Blast:Putative inositol monophosphatase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050725">
        <property type="entry name" value="CysQ/Inositol_MonoPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028:SF4">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00074068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GIY08333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="298" mass="32476" checksum="A92C87FF40CBC0DF" modified="2024-11-27" version="1">MEVISLKHLLSVCVNAAELGGLKVRDVRLSSNLKQISKGKTKEGANDPMTYGDLLSHRTMLYSLKKSFPHLKIVSEEHDENEIEPHDIGPPVSSWIPVDKFVGDIFIPNDDILVWIDPLDATQEYTENLLEYVTTLVCVAIKGRPTIGVIHQPFENKTIWGWTGKGVSDPSLSLEIKNHNWNQSPTIIVSRSHAGKVKEVARAAFGPETKVVSAGGAGFKSLQVAQGKADAYIHVTLIKKWDICAGNALLHALGGKMTALDGSSIDYGNPLEVKNERGLLATTHDHASFVQKLASLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QJ98</accession>
    <name>A0AAV4QJ98_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Recombination activating protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_298151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006479">
        <property type="protein sequence ID" value="GIY10133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QJ98"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY10133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="50" mass="5810" checksum="CFFACBC3498D1EE6" modified="2024-11-27" version="1" fragment="single">RHGESSKYSLRYEPIAGEHDDQCVNCHLVTMKLCATTHERLARIGRQRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QKQ9</accession>
    <name>A0AAV4QKQ9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_776111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006290">
        <property type="protein sequence ID" value="GIY08787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QKQ9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY08787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="94" mass="10422" checksum="7F5E899C8BF41330" modified="2024-11-27" version="1">MVRGLNTLHEVKPYIGYLGGPLQNPIAKESALKIQSYEWRRFFNRASRLGEELSCPPPSAVWVARARQSVSGHPQPFSMEKGGGSEKRGLIDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QRL6</accession>
    <name>A0AAV4QRL6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_743981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006719">
        <property type="protein sequence ID" value="GIY11902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QRL6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY11902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="120" mass="13392" checksum="CAF1CB303EC7579D" modified="2024-11-27" version="1">MSQRAQDSVENEHSPEVPKIENLQQGSPRIQSAKHKAKLTGTCSKGHSGDSAAFQYQSALPHLRLLAHTFRACLWGIKDLIPRGTHSAFGLNPYFSTKRFTIANWQWTSSIVKTLLCSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QUZ6</accession>
    <name>A0AAV4QUZ6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras association domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Rassf2</name>
        <name evidence="2" type="ORF">CEXT_204281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01006820">
        <property type="protein sequence ID" value="GIY12629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QUZ6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01784">
        <property type="entry name" value="RA_RASSF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033614">
        <property type="entry name" value="RASSF1-6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22738:SF15">
        <property type="entry name" value="LD40758P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22738">
        <property type="entry name" value="RASSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-associating" evidence="1">
        <location>
            <begin position="265"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY12629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="358" mass="40540" checksum="A2C2103B36DB153C" modified="2024-11-27" version="1" fragment="single">MWKCHKCGKPVFLVKSGQHAEHKGVPYCHVPCYSVLFGPTLFGHGSQVEAHTSFGKNVNRQGTPVPRSHLEAKLRLYNNFFEGKAGIIQSRERNGRLILEGSLRIFWGVSNVIHLKEDHDDRIPVRRRKSCLPHLIPESIPSAKTLNNNEKPLTNEEKTALVEKDPNLLNSLLSLPMSDAVPLSDINLEVQNIEKECSEENAITPTHYKTLPAGGLRSSKSDHAHTLTNENTVKDKCNNVVQLRRRPRVQKSKLKRRCSINGHYYNRETSVFTPAYASITGVWVTSLVTAPEVINMLLDKFKVVNNPEDFALFVVKDTGERRCIQDHEYPLLVRVMLGPSEDVAKIFIMNKYLAMEIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4QYA6</accession>
    <name>A0AAV4QYA6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protocadherin-23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DCHS2</name>
        <name evidence="7" type="ORF">CEXT_2291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007052">
        <property type="protein sequence ID" value="GIY14254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4QYA6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050174">
        <property type="entry name" value="Protocadherin/Cadherin-CA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24028">
        <property type="entry name" value="CADHERIN-87A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24028:SF263">
        <property type="entry name" value="CADHERIN-RELATED FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="6">
        <location>
            <begin position="34"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="6">
        <location>
            <begin position="132"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY14254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="281" mass="30902" checksum="D0A55733D0B0484C" modified="2024-11-27" version="1">MTVIAYDQGTPSLSSTAKLSVTVADTNDAVPEFSKAVYTLEVAESRQPGDTVFKLDARKEDFKYALLNSDEIDVFDVDMSTGDMRLVKALDSVQQSHYRLLVEASVDSDPPKSDTAEVNIIVGTGHGVQLFPSRLYEVTVFENRLAPLVVLDLNAIDEIAHKPVLYSIVGHHYNGLFVMEADTGRLTVTASLDREKKGQIFLKVRAENVGRHRFGREISRSGSGILPFLYPRYCGYRPFHKGGDDASIVDIKAREVIGCIGLSIRVSISASLSIKCLGNKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4R9U2</accession>
    <name>A0AAV4R9U2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_153191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007544">
        <property type="protein sequence ID" value="GIY17776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4R9U2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY17776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="161" mass="18373" checksum="9E17E31FBF7A5525" modified="2024-11-27" version="1">MGNVPIYPRRNKQPPGLSISLKGTDPRNFNWQRKQADVNDGRNDSCDSHNDGTHNKSSIERRNDETNSFWHQHLVKGELIPRILIGKENTRTLTMGGMILVTRTTTMDSLRQLRSKTSIEQEECLLNGYSPSLNTVVGETFNWFNKARLLRNSVSKASQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGS6</accession>
    <name>A0AAV4RGS6_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NARS2</name>
        <name evidence="9" type="ORF">CEXT_363851</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="BPLR01007726">
        <property type="protein sequence ID" value="GIY19203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGS6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="8">
        <location>
            <begin position="220"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GIY19203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="457" mass="52792" checksum="DC8C7D4BC4DEBCA2" modified="2024-11-27" version="1">MLRSFITPILFKRFYSTNSLTTVKEALSKKPVNQKKILVRGRVQALRKYKELCFIDLIDGTCFDRLQIVINVQDKEIPSCGNSIKVHGLVVKSSHKGQEIELVADSWETVGTLPENHPLKDNHNYTPEYIRQFPHLRPRTKRFWCISSIRNHASMAVHKFFQEEEFCFYHTPVLTQNDCEGKEKFSLLNLKSYHLKCCQKNEQSRSGQFHLEALISGLPKVYNFGPAFRTEASRSRLHASEFQMIEAEIAYTESIDDLMNVVEKCLKQVTKSVMDRCPKELNFITKDIKKHEQYLENYVSKSFIKMPYKDAISILQKNNSSFRKPIEYGDDIATAHKQFLVKHCNNVPVFLCTFPSSLTPAYMKIGENNKAYCFDLFAAFGGEICGGGLREDDPEKLMKTGSFNHSSLEWYVDLRREEYLPHGGFGIGFDRFLLSILGISNLKDVIPFPRRKRECKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RGZ2</accession>
    <name>A0AAV4RGZ2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps2</name>
        <name evidence="6" type="ORF">CEXT_791901</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007787">
        <property type="protein sequence ID" value="GIY19727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RGZ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000133">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="5">
        <location>
            <begin position="103"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY19727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="193" mass="21094" checksum="CCB2B3101CD1E5D2" modified="2024-11-27" version="1">MSYFPPLLFEQVWSTMADAAPAGGRGGFRGGFGGGGRGGRGRGRGRGRGRGRGRGKEEKEWVPVTKLGRLVKDGKIKSLEDIYLFSLPIKECEIIDFFLGNTLKDDVMKIMPVQKQTRAGQRTRFKAIVAMGDHNGHVGLGVKCSKEVATAIRGAIMLAKLTIIPVRRGYWGNKIGSPHTVPCKVKVVYSNMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RJL2</accession>
    <name>A0AAV4RJL2_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">H2AZ2</name>
        <name evidence="12" type="ORF">CEXT_520971</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="9">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008063">
        <property type="protein sequence ID" value="GIY21885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RJL2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000005">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8 9" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="10"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="11">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GIY21885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="128" mass="13528" checksum="D33B5C25279D81B4" modified="2024-11-27" version="1">MAGGKAGKDSGKAKAKAISRSARAGLQFPVGRIHRHLKHRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGTQKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RK66</accession>
    <name>A0AAV4RK66_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_740261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01007877">
        <property type="protein sequence ID" value="GIY20418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RK66"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY20418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11327" checksum="589D442F8F8720E8" modified="2024-11-27" version="1">MKSFKNPFTEFSVTQSENYGCIRYEMRRQHPYFKRYFSPNGFPNNRPLIMGTISNAQKLKTTKLITMVILRGNLGFIPSAAFKSSSRPFVLHSWKTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RRC5</accession>
    <name>A0AAV4RRC5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LARGE xylosyl- and glucuronyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">large2</name>
        <name evidence="8" type="ORF">CEXT_477421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008337">
        <property type="protein sequence ID" value="GIY24010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RRC5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000229">
        <property type="entry name" value="Glycosyltransferase-like protein LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY24010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="452" mass="53285" checksum="57E33D795D046259" modified="2024-11-27" version="1">MQMWRLIAEKELLSMLSTSLADQDIFNAVLKQHPYLIYKLPCQWNVQLSDNTLSEICYTEVQDLKVIHWNSPKKLKVKNKHVEFFRNLYLTFLEYDGNLLRRELIGCNNSKVTHVQEALNAIDEDDSCYEFRRARVVKHRTHLYYIEYDYEPTPEGNDVTLVAQLSMDRLQMVEALCKHWEGPISLALYMSDSEVQQFLSYTLSSEILSSRKNLGYHIVYRDGVTFYPVNLLRNVALQQVTTPFVFLTDIDFLPMYGLYEYLKKSVASMGLESSTKQQFMIHFNVSGSLIVPAFETQRYRLTFPKSKAELLSMLDMGTLFTFRYHVWTRGHAPTNYAKWRTATTPYRVQWELDFEPYIVVRRDVPEYDRRFVGFGWNKVSHIMELYAQGYEFVVLPNAFIVHMPHAPSFDIAKFRSSSQYRKCLKVLKTEFVRDISRRYGKQFSAEKKKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RTQ2</accession>
    <name>A0AAV4RTQ2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_495741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008454">
        <property type="protein sequence ID" value="GIY24805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RTQ2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY24805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="116" mass="13429" checksum="5F3ED7C3043A2F8E" modified="2024-11-27" version="1">MKNVHWLPGGRRFAVRFYLVLAGYYFGILPSFEFVQQTKAAKRKAFIFSSLSKNHMGTETNMLKAIRFENICKLLSRGNFWFLQRLKEGKSRVLVRLSDTGVRFAVPAYFQITRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RU53</accession>
    <name>A0AAV4RU53_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="6">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">Dpagt1</name>
        <name evidence="23" type="ORF">CEXT_435151</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="19">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="6"/>
    <dbReference type="EMBL" id="BPLR01008271">
        <property type="protein sequence ID" value="GIY23418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RU53"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048439">
        <property type="entry name" value="DPAGT1_ins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21383">
        <property type="entry name" value="DPAGT1_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="DPAGT1 insertion" evidence="22">
        <location>
            <begin position="230"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF21383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="GIY23418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="317" mass="36652" checksum="A81376EB9DD9CE35" modified="2024-11-27" version="1">MCLHFRPEAMGVICGSVFLIIMFIFIPIPFIQYWTTNLEVPFPHHQFVELVAALLSICCMLFLGFADDVLDLKWRPLYYVYMGMLAVFCTNAINIYAGINGLEVGQATVICASIVIFNVIELWGECWNAHLFSLYFMIPFLFTTLALLYYNWYPASVFVGDTFCYFAGMTFAVVGILGHFSKTMMLFFLPQIINFLFSCPQLFHFIPCPRHRLPKFNKEQNILQFSTVIFKENSLPFLGHFSLFIAKTFRLVHIKEITKDGEVYLECSNFTVINYMLKIFGPTHERTLTIYLLAIQVLCSCIAFSIRYGLSRVFYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4RZZ8</accession>
    <name>A0AAV4RZZ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_751771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008655">
        <property type="protein sequence ID" value="GIY26259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4RZZ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY26259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="91" mass="10374" checksum="063E3F686D868D66" modified="2024-11-27" version="1">MWNFVPSILSDVTLSVLENNDRFLACVLVKLAGSDTSSEELPICISEDCACFPELLFDQICVDKIFSGFSLIADLIEKNMERKERYFQMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4S269</accession>
    <name>A0AAV4S269_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EVAR_53829_1</name>
        <name evidence="2" type="ORF">CEXT_296801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01008903">
        <property type="protein sequence ID" value="GIY28084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4S269"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY28084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="109" mass="12556" checksum="317B162CA6372F4D" modified="2024-11-27" version="1">MVHRNTNNRWTIIRVMHYDNKFYFSNSHSCGRKGSRANDSHGKACVIECDTFDEFVRICKRTTGNKNVQFTLDYVDVENFEINDDSKETETHQSTERVAAAAASQMINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SBN5</accession>
    <name>A0AAV4SBN5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G_PROTEIN_RECEP_F2_4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AVEN_121184_1</name>
        <name evidence="2" type="ORF">CEXT_266481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009138">
        <property type="protein sequence ID" value="GIY29840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SBN5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053231">
        <property type="entry name" value="GPCR_LN-TM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902">
        <property type="entry name" value="LATROPHILIN RECEPTOR-LIKE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY29840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="136" mass="15432" checksum="FFA3CDBCF42843A9" modified="2024-11-27" version="1">MVSNFSDKVRYFLYLKLSVVLGLAWTLGLIAGLTRMDAFWYPFIILNGLQGALIFIAFTIKRNILHMLAVKLKIRSEKYSMGKRTGIKAAMYSSLSNLTTLQTSLSSQIPTLSRQQEMLKAVRKINPDSVIDDKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SDL8</accession>
    <name>A0AAV4SDL8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_660821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009448">
        <property type="protein sequence ID" value="GIY32059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SDL8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY32059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13315" checksum="C52F649B80D0C523" modified="2024-11-27" version="1">MIASIVENGGIISFISVIANWGFYIFIQIIGVLLVGIKILINYVGELVATKTVVVGNKDKPNIATRDYVRPNTIDGRHIIYHRNKHTYRSRNYVPNMYFSKRRCDWDFCRTWFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMD5</accession>
    <name>A0AAV4SMD5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_679091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009939">
        <property type="protein sequence ID" value="GIY35603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMD5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="106" mass="12250" checksum="E8079694F480AE43" modified="2024-11-27" version="1">MMSSRKAEYFPHQVRWQNICHENHSLAPMQSRTKNTLQDEQLGDVRFLRGSCGVCFSSGTGGECGLRATVRLDQRPQNREAAFARWKSLDPREMLTGTRSFEQHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SMM5</accession>
    <name>A0AAV4SMM5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_254061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009776">
        <property type="protein sequence ID" value="GIY34501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SMM5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY34501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="173" mass="18288" checksum="9CD5A51DB61B2762" modified="2024-11-27" version="1">MHAAPEDNLPRSVSLAVISTRCEREGQGGSKSPNDVGPSLIAPCDDVNPISISFPPNNPSGGPASVQEVHPLERGHASPSLRSFRNSPNPPFAFKCQSISGPPPPGGFLTSVGTVCAEASVIRYEPSYVTTLREVIERRVIASMTCRCLSSDRAPAPIGSGGRRDKAPPQHCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SRJ5</accession>
    <name>A0AAV4SRJ5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_5563_1</name>
        <name evidence="1" type="ORF">CEXT_704631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009743">
        <property type="protein sequence ID" value="GIY34248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SRJ5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46830:SF1">
        <property type="entry name" value="ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46830">
        <property type="entry name" value="TRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY34248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="198" mass="23901" checksum="0AE3855BA9AF51FE" modified="2024-11-27" version="1">MVKNISILEISFKRKPTHIFEKLLSSVYHSSDIARLEILMEYGGIFLDTDTYVIKSLDYFRKFEMTLGWPPSQNLGTQLLIAHKNARFLKLWYNSYHYYRRERWYYNAGELPTQFILERMPYLVHRKVPYDFGVHNLVHLLYGTCTSEWKDYHAIHLLVRHKNYLLPGDTVEEFNEENIKQYNKTFGEMARLVFIWIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSC9</accession>
    <name>A0AAV4SSC9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_688241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01009977">
        <property type="protein sequence ID" value="GIY35904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSC9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY35904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="111" mass="13136" checksum="2308D8498D745EAA" modified="2024-11-27" version="1">MQNRNQDPVKLHLYNAVTIGPHCTVQNLEIEIQIGQKFMLLQSFVYRPLGLELHTFGNKWDLLDWTKSGSVRITCFEYEYLIYKPSLVNKKYKIRCALLKCIFVITLWQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SSU3</accession>
    <name>A0AAV4SSU3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_727961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010130">
        <property type="protein sequence ID" value="GIY37155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SSU3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="112" mass="11735" checksum="131A0CA70BE7AC22" modified="2024-11-27" version="1">MGIQIGKAVENCKTVNSNLSPTDVSGTEMAEYPLTGLLSTATTRTSRCPSRSSPRWTACPAPCSRAAPPSPSSPASRSRRAGVIIPVSRFGVEAVKSTTRRTKELVGGGEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4STA9</accession>
    <name>A0AAV4STA9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_289131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010155">
        <property type="protein sequence ID" value="GIY37320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4STA9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY37320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="34" mass="3519" checksum="D3A178A0A600A17E" modified="2024-11-27" version="1" fragment="single">MDQLAQAQSVPSGGLSTSTSTADRSHAEEDALTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4SYQ1</accession>
    <name>A0AAV4SYQ1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_648841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010258">
        <property type="protein sequence ID" value="GIY38111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4SYQ1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY38111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="141" mass="16140" checksum="A2B3DF78661FEC81" modified="2024-11-27" version="1">MKESNLSIHTFVDASKTAYAACIFLRSESRVNEIRWKFNPPSTHDGKEGIKKTARKSTGKISRKDGIIRLAKLRTEKENILRPIQRLHPMELTPNYEQVVPETQKVPEVVTEYPELSIDSNETVPVSRSGREIKPVKRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T173</accession>
    <name>A0AAV4T173_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_176978_1</name>
        <name evidence="1" type="ORF">CEXT_152031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010419">
        <property type="protein sequence ID" value="GIY39186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T173"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026120">
        <property type="entry name" value="TMEM11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14972">
        <property type="entry name" value="Mito_morph_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="95" mass="10832" checksum="A27FCDE68A78EF4A" modified="2024-11-27" version="1">MENNKPPKVFTNPRPPHLEEDVMLSYKKFDIKVIEDNPHYSSKTQLNDALRGEKSVIVIRDKKLGNDTIMWLTLGQCIQHLTLATAMGAVFAHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2025-10-08" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T1N5</accession>
    <name>A0AAV4T1N5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Apolipophorin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">APLP_5</name>
        <name evidence="1" type="ORF">CEXT_59561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010439">
        <property type="protein sequence ID" value="GIY39271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY39271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="2183" mass="250394" checksum="149245FE2FF696FB" modified="2024-11-27" version="1">MGEIQWEPTKRIAFNTDGSHGLSGRRRICTVNFEGSSPFRGYESTTAKVTYNNDGVTVNTDVETMWNRNKITSSLSVSKRIQLFNKSLEGKFSFTSPFRNYENVQVSTFFDMNEDSYKVNIDTQLPHRSTASFNSQGKMSNWNDIEVNAVVIGNFPRYMDAQKASIDFVHKLKDAKLRTTVDTSYGNDRLTVVLIGLTESGYNSRNSEFSFTVNTPFRGYEELKADFGHNQRGYEYLTKLQMNKNKLSGSLTHKLNIRDALNFDTVLELASTSSIPNGKISIVQSSNGRQLEHTSFVQWDKNNKIHLNAHYLDKVFLKEILVKLSTPYRDYKELEMKASMECQDWEHKGALSFVWNRRNKMTLSAVARNYRWESLDSTVEFTSPFRGYEYYSATVKYDLTDPQKKAEASFLWDVTNRKSIVAKGNLLYSSRLSSLDLSLTTPFSDFERVAFTTKYEGSDTQQNLNVLYERGWRRINLSGRSIIRTNDAEINVDFSSPYRTLQELSASAKYSKIRYGMTGEASVQWNRNNKYKTNVEYELRGSSGKGSIEVLTPINNFRKVNLDTKGSYSRSAMEYEVSLGWNDNQKIVLNYDLTKNREESEMNIKFLSPFAEYREIIGKSSYKWRSGHYEHDVKLSVNQDKIYEGSFVGKYGGDHLAEIRMKLNSPVRPLRDVQLSLTVDLNSELFQLISTLKCENENADIELLLNKKMGQFYEGKLNVNTPFEGFKSLSFYSSLRNDRNQFIDGQLKIVTPFEMLKNFNAYCEFKSDDEGYKVNLKADTPNKNANILGKLSNSQFKPFLASLEIEAPFTSFKSVSTNVELNMMKWNNMDAKWIMNSGKFSHGLDAKFFQENDMLEVKLSAQSTSLRSKSAVVSVTADYKDLNRISTEASIEVFGNVHYMNGQFKSSGKMSEFETKMESSLLPEREAKITAKLSRRRNDRVLEAEINAMFAGNAHELTAKYENKGNQVSANAKIDSNMLSFSTLESEAKYINSNGRDMEASFSVSTPYTSHTFKSSLKNYEGEKIAQMKIECPMVSFLNPFTITSTFKHEGYSSMDLSLSVSTPGKEIRVTGNMKNNGWQNAEAFFVINTPYDALRMVRVDGRFSNDRYQNIDANFQIGTSYDNFPSLGVTSKLSRTEGSEEMSLMLRLPLRNYRSVQLLGNVHYDPDYSSADSRITFTLPKSKYVVYGQYGLSRSRISGRGEVEFNNQKWSATGRLERNSENKDVSLSISTPSSQTYTFGGAYGSSGNRQNFAMTYSSPSNERYSWNSTLNYENIGSFSLDFQAESPFYNYRTISGIINQQSNSNSFSTNVEYIKNGRKGFVKAFHRKQRDGLKGSVQMGCPYTKDLKLSYSRVKKYTNIEDSVEFDYNRAKQFKMEVILFGEKSSHIVLDVPVLPLTVTADSKKISNGREFNFRSNYFSRVVSFRTSHQWDSRQILHDAAFSWDERAEKRISYDFKLAKTETGRELYGRLDTPLRSLMLKGNFTKTNLASSGGIDFCWDAARSMEKHIAIGVLHADISTDSKTSHKLEIVMEHPKLSKDIVQTNIITYSPNEVHVKSKFQYSRERRHDLLMELTATDVSKNYRDTHYKAEFFLRHPASNMDIRAAGEAMNTRFESTAYLRLNSLDRHQAQNVRELKAKIMKLRQEIEMMVRSNDDQMKVLGKVSGRNGEYDITLDRMTNEQKDLSTRITYSRRNSAVDISVMNTENTGVQISASFPKESASLKIAHSKRGNQMTDASVFLGLEGSKVLKSKINWRPKMLKDLRINFGETLRGVLSSNKARYETWSSNIAEELSTRATIMSRVMSDLLAPFIEDLKNGVSGIGDDLSSAKESAKSMYYRNEFHMRDIVAEVHIMKVVASDVANGLALGFEVLYNITVENVEDLYYTLYYTCVDYCDYMYKVRTEMMWKAEKYLQSARKYLNKAMVICAMKIDEALERASAAFDRWSDVVVLKFDKWLRSYAPCIIDGYYYTKNAADRIRYSINELSDCVVTNRYYIALTNYATSVANTFKVLRDYEYAETTRYIVNRLYDINFLDSIMNHPTVDKISEVANSALRKSVEVYHNLGMDVVLAHAADAASDYLQKLAFSAAQEYFSEFYQTKAGAKYDFEPERGHIALEVTLPVERESLADLFDYESYPEYKQVMNVNHMAMEYYEDFCFWDFYYKFMKYFTPSYWLQPSVLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5R3</accession>
    <name>A0AAV4T5R3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_74561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010716">
        <property type="protein sequence ID" value="GIY41455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5R3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY41455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="84" mass="9263" checksum="99B7507889697B5A" modified="2024-11-27" version="1">MTFNVHHFESPNHLLRPIPQRTGDVPTCLPSRKTSSPPTAKWKGTEPGARESLILMNKDLIPTLHKRSVSRNARMAGACMAGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T5U8</accession>
    <name>A0AAV4T5U8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_257191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01010797">
        <property type="protein sequence ID" value="GIY42083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T5U8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY42083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8225" checksum="26238B8AA3DEEB0E" modified="2024-11-27" version="1">MHSGKKEAIPSVSNCRSNKDKCFLSLFSRGDWSPRGRDTAPFRHLLLDEMPLCCIQRVQLLSRQQIYDRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4T9A3</accession>
    <name>A0AAV4T9A3_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Pola1</name>
        <name evidence="6" type="ORF">CEXT_757461</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="BPLR01010893">
        <property type="protein sequence ID" value="GIY42769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4T9A3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861:SF1">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="5">
        <location>
            <begin position="11"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY42769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="220" mass="24791" checksum="410BC5C3BF88E511" modified="2024-11-27" version="1">MLFLQDKFSCRYIIQEILSNKSKDEIVDNIHSHLISLGEAVTQGKKPLTDYVIYKQLTKNPEDYANEKNLPHVLVALRTNAKGGKKLKMGDTVGYIICLDGSDLPVTQRAYHPDELKSNEALKIDVSYYLTQQIHPVISRLCAPIEGADAAMIAKLLGVFDASKYQSMIKTVEDEEDKFLNPSSLFDDEERFKDCDKLILKCPAPSALKKLSWTVHSERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TG67</accession>
    <name>A0AAV4TG67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AVEN_158128_1</name>
        <name evidence="1" type="ORF">CEXT_486001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011026">
        <property type="protein sequence ID" value="GIY43760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TG67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY43760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="229" mass="27253" checksum="13CD26675D66B1A3" modified="2024-11-27" version="1">MIIRLVEEEHQYQKLETSALEDEALDTYRTVLDEVIAPKLELMFKNIPQKKLDAVNKRLFFFQFAYVMEQNNVPDFRKYGVRSNAFIEGWALYAEYLGHELRLYNDPYMLFGHLSYEIFRACRMVVDTGMHVLGWSRQQAIDYMMNHSASPLNNIEREIDRYITWPGQACSYKYGELKIKAMRKRTEEAMGDAFDIKEFHDIRFHNCNEQRLCTHFKNEKNCSSVEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4THY2</accession>
    <name>A0AAV4THY2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_453731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011222">
        <property type="protein sequence ID" value="GIY45007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4THY2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="180" mass="20707" checksum="32B7FE04590786C0" modified="2024-11-27" version="1">MQQKESAPRFERSSDPCLPYISPAIHKPSNARDDKKSTSGVPRPTTSASAPATRRPTPTRRCLFKNKIKNHSADEVKSYSHLVRSQLLGLDLTLRRCQQSFQLWPLKNPTLFSAPSIRKSAPWERSNVKGSSRNSKLAPWKTPTTWRARSPPSRQIALFKYFQHYDYPRTKFQDRNLAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TJG6</accession>
    <name>A0AAV4TJG6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_498631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011243">
        <property type="protein sequence ID" value="GIY45211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TJG6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY45211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="7746" checksum="355AED28F988A86E" modified="2024-11-27" version="1">MRFAIVESVTVSGGRQTKGRRAAGKLPEHPSRHSPSPSHWKRASSRNTRESTMNGVPSKSPLISLCVDFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TX67</accession>
    <name>A0AAV4TX67_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phospholipid-transporting ATPase ABCA1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Abca1</name>
        <name evidence="7" type="ORF">CEXT_456221</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012020">
        <property type="protein sequence ID" value="GIY50749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TX67"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000933">
        <property type="entry name" value="ABC transporter A family member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1111"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="691"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GIY50749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="1225" mass="138094" checksum="090692FF79B2A959" modified="2024-11-27" version="1">MEANLTLEEQVAVVLDKSSGQVSFCKDSRDDSILCALSAVDKIAITADRLQDLVFQKLLISVFRIPGCEGVLKEAEVDKQEAGKTLEILSSAPAIISRLTNHLESVTTLMHPDIKELFQKLDKGVQWLASPEALSTGGQILCGKPLTSLSRRFMLLSPEDAENKIEEKELLRLPTDFCRHGYKEIMKMRGGAILWGFLKPLFRGKILYAPKNYGPALTIISKINETFNNLEEQVGFVKAAAEGSTGLHYLQRKNETLQSLQKLLSSKAISKFLGSQSWSAALSWLEAPSSSSRSLLHLVELVGNVTECISLDRFIGFDTEEELEAAAATLHDRREFIAAIVFKKDQHVEKRSTEGKRRGHLPRNVLYKIRMDIDNVPTTEYIKYRWWRPYPYDDFFEDLRYFRGFLQLQDTIDSAIIDLQSEIPGSSSEVKKYLQQFPYPCHQRDKFGTLLKGSMPAVMTISWVFIVAFLVRERVLDRELELDETLGVMGMRRSSNWLAWFLTGFSVLLVSVIGIVAVLKWGGITPNSDPVVLFLFVADFAVLLIAYCQLMSTFFNRASTAALLSVLLYVLSFFPFLLFVTWELDFLYEDQGQGVHWSNLWQSPVAEDRMNFGTTLIAMTLCSAVYFFLSWYISRIAAGLKSRKPLAWYVLLKPPTFNESKKENGFETNTKSRSMLEGIKNETDAKRNIGITLNNVHALYSKKGSKEWRALSGLNLDLYEDQITALLGHNGAGKTTTIKILTGRILPTAGTVSLYGFSIPEQLTEARKLIGYSPQNNTLYDKLTVKEHLNLFARLKGILGHKEVKKEVDEMLDRLNLVEKQDECTETLSGGQRRRLCVGIAFVGGSKVVILDEPTSSVDPVARRKIWDLILSYKKRTILFTTHHLDEADILSDRVAILHKGRMLCCGSPLELKGRFGSGYRLSILPAAEKSEHEERDSGRASSIMEYEEPVNVDCDGVMECIQTYVPDATLLENDDSHLVVSLPADPLTSKPLSEFFTHLEKCLHLWGFQSCSLSSATLEEVFLTLCRLEDAKAAHNSDKFTDVSPFRLKKTHETTFIQKEDDFCKKAMVIEMKDNDTSTSKDHCFSNCHLKCNQLIALVKKRFWHTKKNWKALTSSIVMPCIFIALAMGLAVGRPQKAPDPSIELTPSLYSNKDHKAISFFAWDESKTNLGNLLLEVLKTNTSQKEICDEGSPNCHYFNKESRTMNGPLSRCLCEEECPAVIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TXV6</accession>
    <name>A0AAV4TXV6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_121301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01011992">
        <property type="protein sequence ID" value="GIY50535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TXV6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13323" checksum="347EA1C047345AD7" modified="2024-11-27" version="1">MFEITFSRVLTAEWKFVECRKGLLYWSSGDVCWQCGITLKFESICCAQYINSCKNRGDSRDSEIGHMCNLYTTHKCGALTVTYLLVDKDRFLPLILGRRDVGDIQRRIRDMQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4TYJ8</accession>
    <name>A0AAV4TYJ8_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_644151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012013">
        <property type="protein sequence ID" value="GIY50726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4TYJ8"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY50726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="80" mass="8717" checksum="F5A2D835650055CC" modified="2024-11-27" version="1">MSPRRSVFVVEGGLMCDLADRFFCEAKQCGCVSPVVLSAMGFGAAVRSPLAFGQYTVKRVKRGKNGEETLLVQMKLNENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U5C6</accession>
    <name>A0AAV4U5C6_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_290871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012316">
        <property type="protein sequence ID" value="GIY52994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U5C6"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY52994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="114" mass="13049" checksum="35E26AE800EF4FAA" modified="2024-11-27" version="1">MLFHFSLLRHHQTITIYSEETKHGGDDEGYEGKTGLSTWEKLLSGVYVRKIKEAFSYLSHPKDNVTFGTEQAVPLITSATVTGRVGKKDGSEMFWAVNKRTWKQSRNLYDNRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4U8J1</accession>
    <name>A0AAV4U8J1_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein obstructor-E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">obst-E_8</name>
        <name evidence="8" type="ORF">CEXT_82841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012472">
        <property type="protein sequence ID" value="GIY54113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4U8J1"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF108">
        <property type="entry name" value="OBSTRACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="5"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="127"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GIY54113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="202" mass="21601" checksum="107AF1AFB3D03D98" modified="2024-11-27" version="1" fragment="single">SAQRGNVCKKENGLFAHDQYCDYYYECENGVAQEKACPNGLAFAGKGRGLIGGCDYPHRVGCPGGDGAVMGQTQSEPKTANGCTECSPIRPAVPDTGNAGTELLPSSSAHSPFCTTMSSTHFDWLFPAICKDQPNGHIPIEKSCGRFWLCVGGYPRLQRCPAGLAFSQTNLRCELSQNVPGCEPPPPPQLQTMRTMPKSVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UDD2</accession>
    <name>A0AAV4UDD2_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_94311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012684">
        <property type="protein sequence ID" value="GIY55833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UDD2"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY55833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="74" mass="8193" checksum="28EF330C3A80CF58" modified="2024-11-27" version="1">MPNTKTQIPILMVKPVSRSSFARGHVNEEQLMAASDRLPPLPNSCAALCPKGDREELFCKAQPVVWPFSKNPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UFE9</accession>
    <name>A0AAV4UFE9_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_260481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012776">
        <property type="protein sequence ID" value="GIY56522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UFE9"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY56522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="67" mass="7243" checksum="FE184D03E9B0BA54" modified="2024-11-27" version="1">MNPQALNINNEDKSGGITGGKVIFSDAFQINQQCYQQGISDEAPPSHSRQVASYGVNLNKAFETILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UHZ4</accession>
    <name>A0AAV4UHZ4_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_458751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01012896">
        <property type="protein sequence ID" value="GIY57373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UHZ4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY57373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="98" mass="11008" checksum="3D70E1CF16ABA43D" modified="2024-11-27" version="1">MMLWRGVPSESGVYMSECIYAPDLTPNVQTQQGPKLSSIESAIGQSTHEALGPLTSRGLELGRRRKVLTTTDNDWTNFESKAKFGFSFRHHHNVKSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4UMV5</accession>
    <name>A0AAV4UMV5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_473881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013147">
        <property type="protein sequence ID" value="GIY59045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4UMV5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY59045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="230" mass="26331" checksum="6B78FC96C4BFE5F2" modified="2024-11-27" version="1">MTVYESFARNTARIQNNKNKPGGIAKAHLVCDYDIARRDSLSSAIVRFDYPFIRLSIFIRHALKNGLEAVRIMYKEVGYVSPLPKSCDSNLKITEMLCCLTAMPIKLLKGIQSFYSIFCSYACTVRDCCRSPGLKNRMPRQVSKNLLDFPNPITVQREISRPKRRLPEDWEVETELHGPTLDESASCVNCGGDDVPKWRICFPFLLKTQDKFFKINRPSPPIRDLCEVQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V2Z3</accession>
    <name>A0AAV4V2Z3_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_299011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01013899">
        <property type="protein sequence ID" value="GIY64597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V2Z3"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY64597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="90" mass="9928" checksum="EC6133B962F2692C" modified="2024-11-27" version="1">MDWLLCEGTSKGCRQRNLDKNLQENKARELRRCLGESAEKRGGHAVKAEEKPVHLDPEHYGSHVANAAVSSPLGPDVSGAMCAWKFLVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4V934</accession>
    <name>A0AAV4V934_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_798211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01014132">
        <property type="protein sequence ID" value="GIY66563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4V934"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY66563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="78" mass="9192" checksum="C35B5F6328F417C6" modified="2024-11-27" version="1">MDEHTVECLVKYSPGHYSHLLLDLPPQLPLLLKRVEEELIKGIESRLHQRVRVCYSEGQKREIITGDVLSEKRIRNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VT78</accession>
    <name>A0AAV4VT78_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_701371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015081">
        <property type="protein sequence ID" value="GIY73451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VT78"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY73451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="71" mass="8400" checksum="DB6DCEA83FDAA4A4" modified="2024-11-27" version="1">MMSSDNQTESSYRLKNRKDPPLNLKLWIGDVSILDDELVSVHSKLRFSHQGSRNSQKWCFHCELVTRIEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4VZB0</accession>
    <name>A0AAV4VZB0_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">General transcription and DNA repair factor IIH helicase/translocase subunit XPB</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DNA 3'-5' helicase/translocase XPB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">hay</name>
        <name evidence="20" type="ORF">CEXT_106511</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="BPLR01015260">
        <property type="protein sequence ID" value="GIY74793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4VZB0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 20" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="311"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="526"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="GIY74793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="745" mass="85730" checksum="18F2F3391FCFC1E9" modified="2024-11-27" version="1">MGKTSKDWKKGKKKFGKRGFEEEYAEEETEADIIPAAASQQIDTGSQEDEFGAKDYRKLMELRLDHDSRPLWVAPDGHIFLEAFSPVYKHAHDFLIAISEPVCRPEHIHEYRLTAYSLYAAVSVGLQTDDIIEYLRRLSKTSIPDGIVEFIKLCTVSYGKIKLVLKHNRYFIESPFPEVLQKLLKDPVIQECRLKRDADDVGLIAGSDPTKMLYSTSAENASEKAEAVPDDIFNFYEKLEREDEEKEDTQTVAVEINQEKIEVLQKRCIELEYPLLAEYDFKNDTVNPDINMDLRPMAILRPYQEKSLRKMFGNGRARSGIIVLPCGAGKSLVGVTACCTVRKRCLVLCNSGVSVEQWKTQFKMWSTADDSMICRFTSDAKDKPMGCGICVTTYSMITHTQKRSWEADQVMNWLKEQEWGLMLLDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIQDLNFLIGPKLYEANWLELQNGGYIAKVQCAEVWCPMTPEFYREYLIARAAKKLLLFVMNPNKFRACQFLIRYHEVRSDKVIVFSDNVFALKHYAIKMNRPYIYGPTSQAERMQILQNFKYNPKVNTIFVSKVADTSFDLPEANVLIQISSHGGSRRQEAQRLGRILRAFTEEYNAFFYTLVSQDTMEMHYSRKRQRFLVNQGYSYKVITKLMGMDETQLLQQVLAANDADAEDEKIPAEFSGGKQQVSRRVGSMSSLSGADDAVYMEYKLKREKHPLFKRFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W259</accession>
    <name>A0AAV4W259_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sprouty-related, EVH1 domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Spred2</name>
        <name evidence="6" type="ORF">CEXT_772411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015430">
        <property type="protein sequence ID" value="GIY76066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W259"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10574">
        <property type="entry name" value="EVH1_SPRED-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000052">
        <property type="entry name" value="Sprouty-related, EVH1 domain containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041937">
        <property type="entry name" value="SPRE_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007875">
        <property type="entry name" value="Sprouty"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11202:SF3">
        <property type="entry name" value="SPROUTY-RELATED PROTEIN WITH EVH-1 DOMAIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11202">
        <property type="entry name" value="SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05210">
        <property type="entry name" value="Sprouty"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51227">
        <property type="entry name" value="SPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="5">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GIY76066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="444" mass="49616" checksum="5A305F52ED136138" modified="2024-11-27" version="1">MEGSHEDGNYLVRVRAQVMTRDDSTGGWVPMGAGGLSYVSVCKGSVSSEEDKVEYLIYGKRLADQTVVLSCTIKKDFQYNKVMPTFHHWRTGDKKFGLTFQTAADARAFDKGVRMAIEDLSDGIGDFPNFHDSDIGEDDVFMTLELPIDSHSSSGSSSFSGGSFRHPLQNLDPATSPYTHPHANHHHLHRMNFIRSPRFPAGINPSSNNNIGGYVPDPTSRSRHEGAWTNKDPSRVSRKDYLVDLDKIEMTGDLNSYVQLSRDKGSRIEHDYSYPIVDSYGKPGNRDTLGSLKKPNNFDAFNCQTAPQLPVKAKKKNSRWRKDARRSLTVARAQCRHCLEMYSPEDNRPGSCEYGPDAVLKCINGASCVYCAQCMLYHCMSDSEGDFNQHPCSCETSDGHCSKRWTALTLLSFFVPCLWCYLPFRACHRCGIQCGMCGGRHDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W2H0</accession>
    <name>A0AAV4W2H0_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_427901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015436">
        <property type="protein sequence ID" value="GIY76109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W2H0"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY76109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="66" mass="7847" checksum="8BDE14B426EE8CF6" modified="2024-11-27" version="1">MKQLTQGRGIGKASWHPMEQQERVCHRLVPPEAPFGQLERVWQISKFLDRLDQLMAFTELRFFGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4W9S5</accession>
    <name>A0AAV4W9S5_CAEEX</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">CEXT_85711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01015917">
        <property type="protein sequence ID" value="GIY79660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4W9S5"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GIY79660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <sequence length="99" mass="11686" checksum="C73BC5F5F13C87E0" modified="2024-11-27" version="1">MKSVTNLLSPAFFRTIHVNNLSKHYSRGKKECFRPLRGDICSKRSITLAAERVLLSASRRHMAEVERFRNMNNQSIYFWAFFETHLGSQVPLREEVLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WPK4</accession>
    <name>A0AAV4WPK4_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">CEXT_259691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016487">
        <property type="protein sequence ID" value="GIY84218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WPK4"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5043853783" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GIY84218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001054945"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13079" checksum="A5FCA2F09EE3D2B3" modified="2024-11-27" version="1">MGSEALWVLCLSNLSIVLSEAPEKKKGKGPMCMRSSARLACWQKVESCTWYKRRVTDKKWVTCRMPLTIHPYGHVACPFPVGRKPPSFPLKLNLYVWAADTFGKEFLARQFTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-11-27" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAV4WU36</accession>
    <name>A0AAV4WU36_CAEEX</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin E</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Ccne1</name>
        <name evidence="7" type="ORF">CEXT_141411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Caerostris extrusa</name>
        <name type="common">Bark spider</name>
        <name type="synonym">Caerostris bankana</name>
        <dbReference type="NCBI Taxonomy" id="172846"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Chelicerata</taxon>
            <taxon>Arachnida</taxon>
            <taxon>Araneae</taxon>
            <taxon>Araneomorphae</taxon>
            <taxon>Entelegynae</taxon>
            <taxon>Araneoidea</taxon>
            <taxon>Araneidae</taxon>
            <taxon>Caerostris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2021-06" db="EMBL/GenBank/DDBJ databases">
            <title>Caerostris extrusa draft genome.</title>
            <authorList>
                <person name="Kono N."/>
                <person name="Arakawa K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BPLR01016726">
        <property type="protein sequence ID" value="GIY86012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAV4WU36"/>
    <dbReference type="Proteomes" id="UP001054945">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
     
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